BLAST output

CMA009C (372 aa)
by blastp 2.2.10 [Oct-19-2004] against nr [Apr-30-2005] (XML result)


		NAD-dependent sorbitol dehydrogenase 2 [Malus x domestica]
		NAD-dependent sorbitol dehydrogenase [Prunus persica]
		Sorbitol Dehydrogenase [Malus x domestica]
		NAD-dependent sorbitol dehydrogenase 9 [Malus x domestica]
		sorbitol dehydrogenase [Prunus cerasus]
		sorbitol dehydrogenase [Malus x domestica]
		sorbitol dehydrogenase [Malus x domestica]
		putative sorbitol dehydrogenase [Arabidopsis thaliana]
		NAD-dependent sorbitol dehydrogenase 2 [Malus x domestica]
		sorbitol dehydrogenase-like protein [Arabidopsis thaliana]
		sorbitol dehydrogenase-like protein [Arabidopsis thaliana]
		sorbitol dehydrogenase [Malus x domestica]
		sorbitol dehydrogenase [Malus x domestica]
		NAD-dependent sorbitol dehydrogenase 8 [Malus x domestica]
		NAD-dependent sorbitol dehydrogenase 3 [Malus x domestica]
		NAD-dependent sorbitol dehydrogenase 7 [Malus x domestica]
		PREDICTED P0623F08.37 gene product [Oryza sativa (japonica cultivar-group)]
		NAD-dependent sorbitol dehydrogenase 6 [Malus x domestica]
		NAD-dependent sorbitol dehydrogenase [Eriobotrya japonica]
		NAD-dependent sorbitol dehydrogenase [Malus x domestica]
		sorbitol dehydrogenase [Malus x domestica]
		CG1982-PA [Drosophila melanogaster]
		NAD-dependent sorbitol dehydrogenase 1 [Malus x domestica]
		NADP(H)-dependent ketose reductase [Bemisia argentifolii]
		sorbitol dehydrogenase [Malus x domestica]
		PREDICTED: similar to Sorbitol dehydrogenase (L-iditol 2-dehydrogenase) [Gallus gallus]
		LP12301p [Drosophila melanogaster]
		Hypothetical protein R04B5.5 [Caenorhabditis elegans]
		CG4649-PA [Drosophila melanogaster]
		Hypothetical protein CBG08605 [Caenorhabditis briggsae]
		similar to CG4649-PA [Apis mellifera]
		sorbitol dehydrogenase [Bos taurus]
		Sord-prov protein [Xenopus laevis]
		hypothetical protein LOC496715 [Xenopus tropicalis]
		sorbitol dehydrogenase
		Sorbitol dehydrogenase [Homo sapiens]
		Chain D, Human SdhNAD+ COMPLEX
		ENSANGP00000011358 [Anopheles gambiae str. PEST]
		Sorbitol dehydrogenase (L-iditol 2-dehydrogenase)
		Hypothetical protein CBG08607 [Caenorhabditis briggsae]
		L-iditol 2-dehydrogenase (EC 1.1.1.14) - sheep (tentative sequence)
		unnamed protein product [Tetraodon nigroviridis]
		Sorbitol dehydrogenase (L-iditol 2-dehydrogenase)
		hypothetical protein [Pongo pygmaeus]
		sorbitol dehydrogenase [Callithrix sp.]
		L-iditol 2-dehydrogenase [Rattus norvegicus]
		hypothetical protein [Pongo pygmaeus]
		Sorbitol dehydrogenase (L-iditol 2-dehydrogenase)
		Sord protein [Rattus norvegicus]
		Chain D, Human SdhNADHINHIBITOR COMPLEX
		sorbitol dehydrogenase [Rattus norvegicus]
		NAD-dependent sorbitol dehydrogenase 5 [Malus x domestica]
		Unknown (protein for MGC:31355) [Mus musculus]
		Sorbitol dehydrogenase (L-iditol 2-dehydrogenase)
		sorbitol dehydrogenase precursor [Mus musculus domesticus]
		hypothetical protein AN9064.2 [Aspergillus nidulans FGSC A4]
		xylitol dehydrogenase [Aspergillus niger]
		Hypothetical protein R04B5.6 [Caenorhabditis elegans]
		ENSANGP00000011378 [Anopheles gambiae str. PEST]
		hypothetical protein CNBL3030 [Cryptococcus neoformans var. neoformans B-3501A]
		xylitol dehydrogenase [Aspergillus oryzae]
		hypothetical protein MG07936.4 [Magnaporthe grisea 70-15]
		L-arabinitol 4-dehydrogenase, putative [Cryptococcus neoformans var. neoformans JEC21]
		SOR1 [Saccharomyces cerevisiae]
		hypothetical protein CNBG4640 [Cryptococcus neoformans var. neoformans B-3501A]
		zinc-binding dehydrogenase [Haloarcula marismortui ATCC 43049]
		xylitol dehydrogenase; XDH [Candida sp. HA167]
		xylitol dehydrogenase [Aspergillus oryzae]
		unnamed protein product [Saccharomyces cerevisiae]
		hypothetical protein MG01231.4 [Magnaporthe grisea 70-15]
		unnamed protein product [Yarrowia lipolytica CLIB99]
		hypothetical protein [Neurospora crassa]
		LRRGT00071 [Rattus norvegicus]
		hypothetical protein MG01176.4 [Magnaporthe grisea 70-15]
		hypothetical protein [Neurospora crassa]
		L-arabitol dehydrogenase [Aspergillus niger]
		hypothetical protein AN0942.2 [Aspergillus nidulans FGSC A4]
		unnamed protein product [Saccharomyces cerevisiae]
		ENSANGP00000011284 [Anopheles gambiae str. PEST]
		conserved hypothetical protein [Gibberella zeae PH-1]
		xylitol dehydrogenase [Hypocrea jecorina]
		hypothetical protein FG04922.1 [Gibberella zeae PH-1]
		unnamed protein product [Kluyveromyces lactis NRRL Y-1140]
		ABR229Cp [Ashbya gossypii ATCC 10895]
		PREDICTED: hypothetical protein XP_510366 [Pan troglodytes]
		alcohol dehydrogenase [Puccinia triticina]
		L-arabinitol 4-dehydrogenase [Hypocrea jecorina]
		hypothetical protein UM00418.1 [Ustilago maydis 521]
		sorbitol dehydrogenase [Bacillus subtilis subsp. subtilis str. 168]
		hypothetical protein CNBK0610 [Cryptococcus neoformans var. neoformans B-3501A]
		L-iditol 2-dehydrogenase, putative [Cryptococcus neoformans var. neoformans JEC21]
		unnamed protein product [Debaryomyces hansenii CBS767]
		hypothetical protein plu1960 [Photorhabdus luminescens subsp. laumondii TTO1]
		unnamed protein product [Debaryomyces hansenii CBS767]
		hypothetical protein CaO19.7676 [Candida albicans SC5314]
		hypothetical protein AN8109.2 [Aspergillus nidulans FGSC A4]
		L-iditol 2-dehydrogenase (EC 1.1.1.14) - silkworm
		sorbitol dehydrogenase [Bacillus clausii KSM-K16]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Clostridium thermocellum ATCC 27405]
		xylitol dehydrogenase [Arxula adeninivorans]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Burkholderia cepacia R18194]
		PUTATIVE ALCOHOL DEHYDROGENASE PROTEIN [Sinorhizobium meliloti]
		hypothetical protein UM02150.1 [Ustilago maydis 521]
		hypothetical protein FG09599.1 [Gibberella zeae PH-1]
		hypothetical protein CNBJ2380 [Cryptococcus neoformans var. neoformans B-3501A]
		D-xylulose reductase (Xylitol dehydrogenase) (XDH)
		dehydrogenase [Schizosaccharomyces pombe]
		tms1 [Schizosaccharomyces pombe]
		Xylitol dehydrogenase [Pichia stipitis]
		unnamed protein product [Debaryomyces hansenii CBS767]
		unnamed protein product [Debaryomyces hansenii CBS767]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Rhodospirillum rubrum]
		hypothetical protein CNBA1020 [Cryptococcus neoformans var. neoformans B-3501A]
		hypothetical protein FG08942.1 [Gibberella zeae PH-1]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Azotobacter vinelandii]
		hypothetical protein AN2666.2 [Aspergillus nidulans FGSC A4]
		hypothetical protein FG06991.1 [Gibberella zeae PH-1]
		putative zinc-binding xylitol/sorbitol dehydrogenase [Burkholderia pseudomallei K96243]
		oxidoreductase, zinc-binding dehydrogenase family [Burkholderia mallei ATCC 23344]
		xylitol (sorbitol) dehydrogenase [Mesorhizobium loti MAFF303099]
		xylitol dehydrogenase [Agrobacterium tumefaciens str. C58]
		putative dehydrogenase, NAD(P)-binding [Escherichia coli K12]
		hypothetical protein [Neurospora crassa]
		putative oxidoreductase [Escherichia coli O157:H7 EDL933]
		Hypothetical zinc-type alcohol dehydrogenase-like protein ydjJ [Escherichia coli CFT073]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Bifidobacterium longum DJO10A]
		hypothetical protein MG09857.4 [Magnaporthe grisea 70-15]
		Hypothetical zinc-type alcohol dehydrogenase-like [Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67]
		hypothetical protein AN4336.2 [Aspergillus nidulans FGSC A4]
		unnamed protein product [Debaryomyces hansenii CBS767]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Azotobacter vinelandii]
		hypothetical protein AN8552.2 [Aspergillus nidulans FGSC A4]
		hypothetical protein CNBA2420 [Cryptococcus neoformans var. neoformans B-3501A]
		IdnD L-idonate 5-dehydrogenase [Sinorhizobium meliloti 1021]
		zinc-binding dehydrogenase [Agrobacterium tumefaciens str. C58]
		ENSANGP00000011286 [Anopheles gambiae str. PEST]
		IdnD L-idonate 5-dehydrogenase [Bradyrhizobium japonicum USDA 110]
		hypothetical protein [Neurospora crassa]
		Hypothetical protein MGC63674 [Danio rerio]
		PUTATIVE L-IDONATE 5-DEHYDROGENASE OXIDOREDUCTASE PROTEIN [Ralstonia solanacearum GMI1000]
		hypothetical protein FG04247.1 [Gibberella zeae PH-1]
		hypothetical protein AN0774.2 [Aspergillus nidulans FGSC A4]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Burkholderia cepacia R18194]
		alcohol dehydrogenase [Oceanobacillus iheyensis HTE831]
		zinc-dependent alcohol dehydrogenase, putative [Aspergillus fumigatus]
		putative alcohol dehydrogenase protein [Sinorhizobium meliloti 1021]
		zinc-binding dehydrogenase [Agrobacterium tumefaciens str. C58]
		dehydrogenase [Pyrococcus horikoshii OT3]
		tdh threonine 3-dehydrogenase (EC 1.1.1.103) [Pyrococcus abyssi GE5]
		L-idonate 5-dehydrogenase [Silicibacter pomeroyi DSS-3]
		hypothetical protein AGR_C_2601 [Agrobacterium tumefaciens str. C58]
		sorbitol dehydrogenase [Agrobacterium tumefaciens str. C58]
		possible threonine 3-dehydrogenase [Pyrococcus furiosus DSM 3638]
		Sorbitol dehydrogenase (EC 1.1.1.14) (L-iditol 2-dehydrogenase). [Escherichia coli]
		threonine 3-dehydrogenase [Thermus thermophilus HB27]
		probable alcohol dehydrogenase (Zn-dependent) [Rhodopirellula baltica SH 1]
		threonine 3-dehydrogenase [Thermococcus kodakaraensis KOD1]
		PREDICTED: similar to Sorbitol dehydrogenase (L-iditol 2-dehydrogenase) [Canis familiaris]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Pseudomonas aeruginosa UCBPP-PA14]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Burkholderia cepacia R18194]
		L-idonate 5-dehydrogenase [Bradyrhizobium japonicum USDA 110]
		threonine 3-dehydrogenase [Thermus thermophilus HB8]
		probable alcohol dehydrogenase (Zn-dependent) [Pseudomonas aeruginosa PAO1]
		2,3-butanediol dehydrogenase [Pseudomonas putida KT2440]
		PREDICTED: similar to Sorbitol dehydrogenase (L-iditol 2-dehydrogenase), partial [Bos taurus]
		Zinc-containing alcohol dehydrogenase [Bacillus subtilis phage PBSX]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Clostridium thermocellum ATCC 27405]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Burkholderia cepacia R18194]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Burkholderia cepacia R1808]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Azotobacter vinelandii]
		2,3-butanediol dehydrogenase [Pseudomonas putida]
		Tdh protein [Mannheimia succiniciproducens MBEL55E]
		2,3-butanediol dehydrogenase [Pseudomonas aeruginosa PAO1]
		PA4153 [synthetic construct]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Pseudomonas aeruginosa UCBPP-PA14]
		hypothetical protein UM00412.1 [Ustilago maydis 521]
		(R,R)-butanediol dehydrogenase [Bacillus cereus ATCC 14579]
		zinc-containing alcohol dehydrogenase, long-chain [Bacillus cereus ZK]
		acetylacetoin reductase [Bacillus cereus]
		alcohol dehydrogenase, zinc-containing [Bacillus cereus ATCC 10987]
		yjmD [Bacillus subtilis subsp. subtilis str. 168]
		alcohol dehydrogenase, zinc-containing [Bacillus anthracis str. 'Ames Ancestor']
		Starvation sensing protein rspB [Escherichia coli CFT073]
		L-idonate 5-dehydrogenase, NAD-binding [Escherichia coli K12]
		L-idonate 5-dehydrogenase [Escherichia coli CFT073]
		NAD-dependent sorbital dehydrogenase 8 [Malus x domestica]
		hypothetical sorbitol dehydrogenase [Sulfolobus tokodaii str. 7]
		L-idonate 5-dehydrogenase [Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67]
		putative dehydrogenase, NAD(P)-binding, starvation-sensing protein [Escherichia coli K12]
		putative L-idonate 5-dehydrogenase [Streptomyces avermitilis MA-4680]
		sorbitol dehydrogenase [Oceanobacillus iheyensis HTE831]
		L-idonate 5-dehydrogenase [Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150]
		putative starvation sensing zinc-binding dehydrogenase [Erwinia carotovora subsp. atroseptica SCRI1043]
		L-idonate 5-dehydrogenase [Salmonella typhimurium LT2]
		hypothetical protein AN2158.2 [Aspergillus nidulans FGSC A4]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Microbulbifer degradans 2-40]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Exiguobacterium sp. 255-15]
		sorbitol dehydrogenase [Bacillus clausii KSM-K16]
		putative dehydrogenase [Salmonella typhimurium LT2]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Polaromonas sp. JS666]
		galactitol-1-phosphate 5-dehydrogenase [Bacillus clausii KSM-K16]
		putative dehydrogenase [Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Oenococcus oeni PSU-1]
		Zn-dependent alcohol dehydrogenase [Bacillus clausii KSM-K16]
		putative dehydrogenase [Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67]
		putative zinc-binding alcohol dehydrogenase [Streptomyces coelicolor A3(2)]
		benzyl alcohol dehydrogenase [Pseudomonas putida]
		TmbW
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Haemophilus somnus 2336]
		sorbitol dehydrogenase [Bacillus clausii KSM-K16]
		sorbitol dehydrogenase [Bacillus halodurans C-125]
		AGR_L_281p [Agrobacterium tumefaciens str. C58]
		zinc-binding dehydrogenase [Agrobacterium tumefaciens str. C58]
		putative alcohol dehydrogenase NtnW [Pseudomonas sp. TW3]
		CG4836-PC, isoform C [Drosophila melanogaster]
		CG4836-PB, isoform B [Drosophila melanogaster]
		XylW hypothetical protein
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Burkholderia cepacia R18194]
		arabitol-phosphate dehydrogenase [Enterococcus avium]
		Putative zinc-binding alcohol dehydrogenase [Corynebacterium diphtheriae NCTC 13129]
		Sorbitol dehydrogenase [Sulfolobus solfataricus P2]
		YjmD protein [Bacillus amyloliquefaciens]
		hypothetical protein lin0506 [Listeria innocua Clip11262]
		alcohol dehydrogenase, zinc-dependent [Listeria monocytogenes str. 1/2a F6854]
		threonine 3-dehydrogenase [Symbiobacterium thermophilum IAM 14863]
		L-iditol 2-dehydrogenase [Bacillus halodurans C-125]
		xylitol-phosphate dehydrogenase [Lactobacillus rhamnosus]
		alcohol dehydrogenase, zinc-dependent [Listeria monocytogenes str. 4b F2365]
		alcohol dehydrogenase, zinc-dependent [Listeria monocytogenes str. 4b F2365]
		galactitol-1-phosphate dehydrogenase [Salmonella enterica subsp. enterica serovar Typhi Ty2]
		hypothetical protein lin2813 [Listeria innocua Clip11262]
		galactitol-1-phosphate dehydrogenase [Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150]
		alcohol dehydrogenase, zinc-dependent [Listeria monocytogenes str. 1/2a F6854]
		mannitol dehydrogenase [Leuconostoc mesenteroides]
		benzyl alcohol dehydrogenase [Pseudomonas putida]
		hypothetical protein lmo2664 [Listeria monocytogenes EGD-e]
		hypothetical protein lmo0506 [Listeria monocytogenes EGD-e]
		similar to Xylitol dehydrogenase [Apis mellifera]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Haemophilus somnus 2336]
		putative (R,R)-butanediol dehydrogenase [Acinetobacter sp. ADP1]
		mannitol-2-dehydrogenase [Leuconostoc pseudomesenteroides]
		putative dehydrogenase [Nocardia farcinica IFM 10152]
		Tdh protein [Mannheimia succiniciproducens MBEL55E]
		2,3-butanediol dehydrogenase (EC 1.1.1.4) [Lactococcus lactis subsp. lactis Il1403]
		2,3-butanediol dehydrogenase [Lactococcus lactis subsp. lactis Il1403]
		zinc-binding dehydrogenase [Haloarcula marismortui ATCC 43049]
		sorbitol dehydrogenase [Oceanobacillus iheyensis HTE831]
		unnamed protein product [Escherichia coli]
		threonine 3-dehydrogenase [Yersinia pseudotuberculosis IP 32953]
		PREDICTED: hypothetical protein XP_510365 [Pan troglodytes]
		unknown protein [synthetic construct]
		threonine 3-dehydrogenase [Photorhabdus luminescens subsp. laumondii TTO1]
		L-threonine 3-dehydrogenase
		threonine 3-dehydrogenase [Deinococcus radiodurans]
		L-threonine 3-dehydrogenase [Francisella tularensis subsp. tularensis Schu 4]
		threonine dehydrogenase [Shigella flexneri 2a str. 301]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Rubrobacter xylanophilus DSM 9941]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Haemophilus somnus 2336]
		L-threonine 3-dehydrogenase [Erwinia carotovora subsp. atroseptica SCRI1043]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Haemophilus somnus 129PT]
		putative zinc-binding dehydrogenase [Staphylococcus aureus subsp. aureus MRSA252]
		Zn-dependent alcohol dehydrogenase [Bacillus clausii KSM-K16]
		hexitol dehydrogenase [Staphylococcus aureus subsp. aureus COL]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Oenococcus oeni PSU-1]
		L-threonine 3-dehydrogenase [Chromobacterium violaceum ATCC 12472]
		threonine dehydrogenase [Yersinia pestis KIM]
		Threonine 3-dehydrogenase [Escherichia coli CFT073]
		sorbitol dehydrogenase [Staphylococcus aureus subsp. aureus COL]
		putative zinc-binding dehydrogenase [Staphylococcus aureus subsp. aureus MSSA476]
		Zn-dependent alcohol dehydrogenase [Bacillus clausii KSM-K16]
		putative zinc-containing alcohol dehydrogenase [Burkholderia pseudomallei K96243]
		threonine 3-dehydrogenase [Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Brevibacterium linens BL2]
		Galactitol-1-phosphate 5-dehydrogenase [Escherichia coli CFT073]
		sorbitol dehydrogenase [Staphylococcus aureus subsp. aureus Mu50]
		putative zinc-binding dehydrogenase [Staphylococcus aureus subsp. aureus MSSA476]
		sorbitol dehydrogenase [Oceanobacillus iheyensis HTE831]
		putative zinc-binding alcohol dehydrogenase [Neisseria meningitidis Z2491]
		threonine dehydrogenase [Escherichia coli O157:H7 EDL933]
		threonine dehydrogenase [Escherichia coli O157:H7]
		galactitol-1-phosphate dehydrogenase [Shigella flexneri 2a str. 301]
		putative zinc-binding dehydrogenase [Staphylococcus aureus subsp. aureus MRSA252]
		putative zinc-binding dehydrogenase [Salmonella typhimurium LT2]
		PROBABLE THREONINE 3-DEHYDROGENASE PROTEIN [Sinorhizobium meliloti]
		alcohol dehydrogenase, zinc-containing [Neisseria meningitidis MC58]
		zinc-type alcohol dehydrogenase [Haemophilus influenzae Rd KW20]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Haemophilus influenzae R2866]
		sorbitol dehydrogenase [Bacillus halodurans C-125]
		putative zinc-binding alcohol dehydrogenas [Neisseria gonorrhoeae FA 1090]
		galactitol-1-phosphate dehydrogenase [Escherichia coli K12]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Polaromonas sp. JS666]
		Threonine dehydrogenase and related Zn-dependent dehydrogenases [Thermoanaerobacter tengcongensis MB4]
		L-threonine 3-dehydrogenase
		L-threonine 3-dehydrogenase [Coxiella burnetii RSA 493]
		threonine 3-dehydrogenase [Vibrio cholerae O1 biovar eltor str. N16961]
		putative alcohol dehydrogenase [Salmonella enterica subsp. enterica serovar Typhi Ty2]
		NAD dependent sorbitol dehydrogenase [Pyrus communis]
		putative zinc-containing alcohol dehydrogenase [Mycobacterium sp. S65]
		threonine 3-dehydrogenase [Salmonella enterica subsp. enterica serovar Typhi Ty2]
		zinc-dependent dehydrogenase [Mycobacterium vanbaalenii]
		Gat-1-P-DH, NAD dependent [Escherichia coli]
		hypothetical protein AN9288.2 [Aspergillus nidulans FGSC A4]
		Threonine 3-dehydrogenase [Idiomarina loihiensis L2TR]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Azotobacter vinelandii]
		putative sugar-alcohol dehydrogenase, probably galactitol-1-phosphate 5-dehydrogenase protein [Sinorhizobium meliloti 1021]
		hypothetical protein CNBC0530 [Cryptococcus neoformans var. neoformans B-3501A]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Moorella thermoacetica ATCC 39073]
		sorbitol dehydrogenase, putative [Staphylococcus epidermidis RP62A]
		carbohydrate phosphotransferase II
		sorbitol dehydrogenase [Staphylococcus epidermidis ATCC 12228]
		Zn-dependent alcohol dehydrogenase [Bacillus clausii KSM-K16]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Oenococcus oeni PSU-1]
		alcohol dehydrogenase, zinc-dependent [Listeria monocytogenes str. 4b F2365]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Mesorhizobium sp. BNC1]
		hypothetical protein lin2812 [Listeria innocua Clip11262]
		Hypothetical zinc-type alcohol dehydrogenase-like protein yjjN
		alcohol dehydrogenase, zinc-dependent [Listeria monocytogenes str. 4b H7858]
		putative dehydrogenase, NAD(P)-binding [Escherichia coli K12]
		putative oxidoreductase [Escherichia coli O157:H7 EDL933]
		Hypothetical zinc-type alcohol dehydrogenase-like protein yjjN [Escherichia coli CFT073]
		6-hydroxycylohex-1-ene-1-carboxyl-CoA dehydrogenase [uncultured bacterium]
		zinc binding dehydrogenase [Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130]
		putative zinc-containing alcohol dehydrogenase [Mycobacterium sp. S65]
		threonine dehydrogenase [Mesorhizobium loti MAFF303099]
		threonine 3-dehydrogenase [Burkholderia pseudomallei K96243]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Ferroplasma acidarmanus]
		threonine 3-dehydrogenase [Vibrio parahaemolyticus RIMD 2210633]
		Threonine dehydrogenase [Vibrio vulnificus CMCP6]
		sorbitol dehydrogenase [Bacillus cereus ATCC 10987]
		putative zinc-binding dehydrogenase [Erwinia carotovora subsp. atroseptica SCRI1043]
		hypothetical protein AN3700.2 [Aspergillus nidulans FGSC A4]
		threonine 3-dehydrogenase [Bacillus licheniformis ATCC 14580]
		sorbitol dehydrogenase [Bacillus clausii KSM-K16]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Burkholderia cepacia R1808]
		alcohol dehydrogenase, zinc-dependent [Listeria monocytogenes str. 1/2a F6854]
		isopropanol dehydrogenase [Phytomonas sp. ADU-2003]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Burkholderia cepacia R18194]
		threonine dehydrogenase [Vibrio vulnificus YJ016]
		PUTATIVE ZINC-CONTAINING ALCOHOL DEHYDROGENASE PROTEIN [Sinorhizobium meliloti]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Nostoc punctiforme PCC 73102]
		threonine 3-dehydrogenase [Shewanella oneidensis MR-1]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Nostoc punctiforme PCC 73102]
		putative dehydrogenase [Thermosynechococcus elongatus BP-1]
		threonine 3-dehydrogenase [Vibrio fischeri ES114]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Burkholderia fungorum LB400]
		threonine 3-dehydrogenase [Xanthomonas oryzae pv. oryzae KACC10331]
		threonine 3-dehydrogenase [Xanthomonas axonopodis pv. citri str. 306]
		hypothetical protein lmo2663 [Listeria monocytogenes EGD-e]
		zinc-containing alcohol dehydrogenase; possible sorbitol dehydrogenase (L-iditol 2-dehydrogenase) [Bacillus cereus ZK]
		putative dehydrogenase [Yersinia pestis KIM]
		putative Zinc-binding dehydrogenase [Yersinia pseudotuberculosis IP 32953]
		probable threonine 3-dehydrogenase [Parachlamydia sp. UWE25]
		hypothetical protein FG07683.1 [Gibberella zeae PH-1]
		alcohol dehydrogenase [Gordonia sp. TY-5]
		putative zinc-binding dehydrogenase [Burkholderia pseudomallei K96243]
		probable zinc-type alcohol dehydrogenase [Rhodopirellula baltica SH 1]
		threonine 3-dehydrogenase [Xanthomonas campestris pv. campestris str. ATCC 33913]
		putative threonine 3-dehydrogenase [Photobacterium profundum SS9]
		L-iditol 2-dehydrogenase [Lactobacillus plantarum WCFS1]
		oxidoreductase, zinc-binding dehydrogenase family [Burkholderia mallei ATCC 23344]
		hypothetical protein [Legionella pneumophila str. Lens]
		L-threonine 3-dehydrogenase [Silicibacter pomeroyi DSS-3]
		threonine(-3-)dehydrogenase [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
		threonine dehydrogenase [Legionella pneumophila str. Lens]
		putative zinc-binding [Sinorhizobium meliloti 1021]
		putative zinc-binding dehydrogenase [Streptomyces avermitilis MA-4680]
		threonine dehydrogenase [Legionella pneumophila str. Paris]
		putative sorbitol dehydrogenase [Yersinia pseudotuberculosis IP 32953]
		sorbitol dehydrogenase [Bacillus halodurans]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Novosphingobium aromaticivorans DSM 12444]
		mannitol dehydrogenase [Lactobacillus reuteri]
		GatD [Klebsiella oxytoca]
		oxidoreductase, zinc-binding dehydrogenase family [Burkholderia mallei ATCC 23344]
		putative zinc-binding dehydrogenase [Yersinia pestis biovar Medievalis str. 91001]
		putative Zn binding dehydrogenase [Bacillus subtilis phage PBSX]
		putative zinc-binding dehydrogenase [Streptomyces coelicolor A3(2)]
		hypothetical protein y1686 [Yersinia pestis KIM]
		similar to hypothetical protein MG01114.4 [Apis mellifera]
		PREDICTED: similar to Sorbitol dehydrogenase (L-iditol 2-dehydrogenase), partial [Bos taurus]
		hypothetical protein CNBC0940 [Cryptococcus neoformans var. neoformans B-3501A]
		putative dehydrogenase [Streptomyces tenebrarius]
		putative threonine 3-dehydrogenase [Streptomyces avermitilis MA-4680]
		putative zinc-binding dehydrogenase [Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67]
		putative alcohol dehydrogenase [Micromonospora echinospora]
		Hypothetical zinc-type alcohol dehydrogenase-like protein yjjN [Escherichia coli CFT073]
		hypothetical protein FG03061.1 [Gibberella zeae PH-1]
		zinc-type alcohol dehydrogenase [Rhodopirellula baltica SH 1]
		putative dehydrogenase [Burkholderia pseudomallei K96243]
		PROBABLE ZINC-DEPENDENT ALCOHOL DEHYDROGENASE OXIDOREDUCTASE PROTEIN [Ralstonia solanacearum]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Rhodobacter sphaeroides 2.4.1]
		putative zinc-binding dehydrogenase [Salmonella typhimurium LT2]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Rhodobacter sphaeroides 2.4.1]
		putative dehydrogenase [Microscilla sp. PRE1]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293]
		2,3-butanediol dehydrogenase [Mesorhizobium loti MAFF303099]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Rubrobacter xylanophilus DSM 9941]
		sorbitol dehydrogenase [Thermosynechococcus elongatus BP-1]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Burkholderia cepacia R1808]
		zinc-binding dehydrogenase [Burkholderia pseudomallei K96243]
		alr5117 [Nostoc sp. PCC 7120]
		sorbitol dehydrogenase [Gloeobacter violaceus PCC 7421]
		hypothetical protein SMa1417 [Sinorhizobium meliloti 1021]
		putative dehydrogenase [Streptomyces coelicolor A3(2)]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Anabaena variabilis ATCC 29413]
		alcohol dehydrogenase [Mesorhizobium loti MAFF303099]
		BH1951 [Bacillus halodurans C-125]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Silicibacter sp. TM1040]
		putative dehydrogenase [Actinoplanes sp. A40644]
		sorbitol dehydrogenase related protein [Thermoplasma acidophilum DSM 1728]
		alcohol dehydrogenase [Mycoplasma penetrans HF-2]
		YAL061W [Saccharomyces cerevisiae]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Azotobacter vinelandii]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Ralstonia metallidurans CH34]
		threonine 3-dehydrogenase [Bacillus subtilis subsp. subtilis str. 168]
		COG1062: Zn-dependent alcohol dehydrogenases, class III [Brevibacterium linens BL2]
		sorbitol dehydrogenase, putative [Silicibacter pomeroyi DSS-3]
		dehydrogenase [Oceanobacillus iheyensis HTE831]
		putative alcohol dehydrogenase I [Bdellovibrio bacteriovorus HD100]
		threonine 3-dehydrogenase [Propionibacterium acnes KPA171202]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Anabaena variabilis ATCC 29413]
		alcohol dehydrogenase [Propionibacterium acnes KPA171202]
		alcohol dehydrogenase [Bacillus clausii KSM-K16]
		sorbitol dehydrogenase [Nostoc sp. PCC 7120]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Methylobacillus flagellatus KT]
		threonine 3-dehydrogenase. [Streptomyces coelicolor A3(2)]
		alcohol dehydrogenase [Geobacillus stearothermophilus]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Burkholderia cepacia R18194]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Rubrobacter xylanophilus DSM 9941]
		probable dehydrogenase [Gloeobacter violaceus PCC 7421]
		putative zinc-containing dehydrogenase [Streptomyces coelicolor A3(2)]
		COG1062: Zn-dependent alcohol dehydrogenases, class III [Microbulbifer degradans 2-40]
		hypothetical protein AN0599.2 [Aspergillus nidulans FGSC A4]
		hypothetical protein AN0443.2 [Aspergillus nidulans FGSC A4]
		alcohol dehydrogenase, zinc-containing [Neisseria meningitidis MC58]
		unnamed protein product [Kluyveromyces lactis NRRL Y-1140]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Pseudomonas fluorescens PfO-1]
		alcohol dehydrogenase [Geobacillus kaustophilus HTA426]
		hypothetical protein MG01114.4 [Magnaporthe grisea 70-15]
		starvation sensing protein RspB [Salmonella enterica subsp. enterica serovar Typhi Ty2]
		sorbitol dehydrogenase [Bacteroides thetaiotaomicron VPI-5482]
		putative zinc-containing alcohol dehydrogenase [Streptococcus pyogenes MGAS8232]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Ralstonia eutropha JMP134]
		alcohol dehydrogenase [Geobacillus stearothermophilus]
		alcohol dehydrogenase, zinc-containing [Dehalococcoides ethenogenes 195]
		PUTATIVE ZINC-TYPE ALCOHOL DEHYDROGENASE PROTEIN [Sinorhizobium meliloti]
		alcohol dehydrogenase [Geobacillus kaustophilus HTA426]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Rubrobacter xylanophilus DSM 9941]
		thermostable alcohol dehydrogenase [Geobacillus sp. M10EXG]
		putative zinc-containing alcohol dehydrogenase [Streptococcus pyogenes M1 GAS]
		sorbitol dehydrogenase [Paracoccidioides brasiliensis]
		ydjL [Bacillus subtilis subsp. subtilis str. 168]
		hypothetical protein AGR_C_5103 [Agrobacterium tumefaciens str. C58]
		putative zinc-type alcohol dehydrogenase [Bacteroides thetaiotaomicron VPI-5482]
		Putative dehydrogenase [Escherichia coli CFT073]
		putative zinc-containing alcohol dehydrogenase [Streptococcus pyogenes SSI-1]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Burkholderia fungorum LB400]
		probable zinc-containing alcohol dehydrogenase [Chromobacterium violaceum ATCC 12472]
		GntP-like protein [Streptomyces kanamyceticus]
		Hypothetical zinc-type alcohol dehydrogenase-like [Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67]
		YAL060W [Saccharomyces cerevisiae]
		putative zinc-type alcohol dehydrogenase [Bacteroides fragilis YCH46]
		Hypothetical zinc-type alcohol dehydrogenase-like protein ydjL [Escherichia coli CFT073]
		hypothetical zinc-type alcohol dehydrogenase-like protein [Escherichia coli K12]
		(R,R)-butanediol dehydrogenase
		putative zinc-binding alcohol dehydrogenase [Bacteroides fragilis NCTC 9343]
		alcohol dehydrogenase, zinc-containing [Silicibacter pomeroyi DSS-3]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Novosphingobium aromaticivorans DSM 12444]
		putative oxidoreductase [Shigella flexneri 2a str. 301]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Burkholderia cepacia R18194]
		putative 6-hydroxycaproate dehydrogenase [Brachymonas petroleovorans]
		putative oxidoreductase [Shigella flexneri 2a str. 301]
		L-iditol 2-dehydrogenase (EC 1.1.1.14) [Mesorhizobium loti MAFF303099]
		putative oxidoreductase [Streptomyces coelicolor A3(2)]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Psychrobacter sp. 273-4]
		sorbitol dehydrogenase [Rhodopirellula baltica SH 1]
		putative alcohol dehydrogenase I [Streptococcus pyogenes MGAS315]
		putative alcohol dehydrogenase I [Streptococcus pyogenes MGAS8232]
		Alcohol dehydrogenase [Streptococcus pyogenes MGAS10394]
		mixed alcohol dehydrogenase Adh8b [Danio rerio]
		putative zinc-binding sorbitol dehydrogenase [Propionibacterium acnes KPA171202]
		putative alcohol dehydrogenase [Streptomyces avermitilis MA-4680]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Ralstonia eutropha JMP134]
		putative oxidoreductase [Shigella flexneri 2a str. 2457T]
		alcohol dehydrogenase (Zn-dependent) [Pseudomonas aeruginosa PAO1]
		hypothetical protein AGR_C_1112 [Agrobacterium tumefaciens str. C58]
		probable alcohol dehydrogenase (EC 1.1.1.1) - Alcaligenes eutrophus
		putative alcohol dehydrogenase I [Streptococcus pyogenes M1 GAS]
		dehydrogenase [Streptomyces fradiae]
		Adh6-prov protein [Xenopus laevis]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Rhodobacter sphaeroides 2.4.1]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Brevibacterium linens BL2]
		alcohol dehydrogenase [Geobacillus kaustophilus HTA426]
		unnamed protein product [Kluyveromyces lactis NRRL Y-1140]
		glycerol dehydrogenase [Pichia angusta]
		COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Burkholderia fungorum LB400]
		Unknown [Streptococcus agalactiae NEM316]
		alcohol dehydrogenase [Tropheryma whipplei TW08/27]
		zinc-type alcohol dehydrogenase [Tropheryma whipplei str. Twist]
		putative dehydrogenase, NAD(P)-binding [Escherichia coli K12]
		Alcohol dehydrogenase (Zn containing) (adh-9) [Sulfolobus solfataricus P2]

gb|AAP69750.1| NAD-dependent sorbitol dehydrogenase 2 [Malus x domestica]
(368 aa)

Score: 369 bits (947), Expect: 7.04525e-101
Length: 354, Idn/Pos/Gap = 181/248/6 (51%/70%/1%)

Query:  19 EKANPCGVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDP  78
           E+ N    LV    ++++   +PA  P +VR++++ VGICGSD+HY     CG F++ DP
Sbjct:  19 EQENMAAWLVDVNTIKILPFKLPAIGPNDVRIRIKAVGICGSDIHYLKTMKCGDFQVKDP  78

Query:  79 MIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPV 138
           M+IGHE AG+V+ +G+ V  L  GDRVA+EPG+ C  CQ+C+ GRYNLCP++KFFATPPV
Sbjct:  79 MVIGHECAGIVDKVGSEVKHLVPGDRVAVEPGISCAHCQQCKGGRYNLCPDMKFFATPPV 138

Query: 139 DGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIG 198
            GSLA  + HPA  C++LPE+VSLEEGAMCEPLSV VHA RRA     + VL++GAGPIG
Sbjct: 139 HGSLANQIVHPADLCFKLPENVSLEEGAMCEPLSVGVHACRRANVGPETTVLIVGAGPIG 198

Query: 199 LLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAV--INTRDLDEHDAALVVQQALDG 256
           L++ + A+AFGA  IV+ D+DDRRLA A++  GAD    ++T+  D  D    +++A+ G
Sbjct: 199 LVSVLAARAFGAPRIVIVDMDDRRLAMAKS-LGADGTVKVSTKMEDLDDEVAKIKEAM-G 256

Query: 257 AQADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYS 316
           ++ D+  DC G   TM   ++  RPGG++CLVGMG   M VPL  A++RE+D+ GVFRY 
Sbjct: 257 SEVDVTFDCVGFNKTMSTGLNATRPGGKVCLVGMGHGVMTVPLTPAAAREVDVVGVFRYK 316

Query: 317 NTYPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLTI 370
           NT+P C+  L SG+++VKPLITHRF G  E  +E AF T+    N A+KVM T+
Sbjct: 317 NTWPLCLEFLRSGKIDVKPLITHRF-GFTEKEVEEAFATSARGGN-AIKVMFTL 368

dbj|BAA94084.1| NAD-dependent sorbitol dehydrogenase [Prunus persica]
(367 aa)

Score: 363 bits (932), Expect: 4.49233e-99
Length: 353, Idn/Pos/Gap = 178/243/4 (50%/68%/1%)

Query:  19 EKANPCGVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDP  78
           E+ N    LV    LR+    +P   P +VR++++ VGICGSDVHY     C  F + +P
Sbjct:  18 EQENMAAWLVGVNTLRIQPFKLPTVGPNDVRVKIKAVGICGSDVHYLKTMKCADFVVQEP  77

Query:  79 MIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPV 138
           M+IGHE AG+V+ +G+ V +L  GDRVALEPG+ C +C++C+ GRYNLCP++KFFATPPV
Sbjct:  78 MVIGHECAGIVDEVGSLVKNLVPGDRVALEPGISCWRCEQCKGGRYNLCPDMKFFATPPV 137

Query: 139 DGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIG 198
            GSLA  + HPA  C++LPE+VSLEEGAMCEPLSV VHA RRA     + VLV+GAGPIG
Sbjct: 138 HGSLANQIVHPADLCFKLPENVSLEEGAMCEPLSVGVHACRRANIGPETNVLVIGAGPIG 197

Query: 199 LLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAV-INTRDLDEHDAALVVQQALDGA 257
           L++ + A+AFGA+ IV+ D+DD RL+ A++    DAV ++T   D  D    + +A+ G 
Sbjct: 198 LVSVLSARAFGAARIVIVDVDDERLSIAKSLGADDAVKVSTNPQDLEDEVSKISKAMKGG 257

Query: 258 QADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSN 317
             D++ DC G   TM  A+   RPGG++CLVGMG   M VPL  A++RE+D+ G+FRY N
Sbjct: 258 -VDVSFDCVGFNKTMSTALSATRPGGKVCLVGMGHGVMTVPLTPAAAREVDVVGIFRYKN 316

Query: 318 TYPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLTI 370
           T+P C+  L +G+++VKPLITHRF G  +  +E AFET+    N A+KVM  +
Sbjct: 317 TWPLCLEFLRTGKIDVKPLITHRF-GFSQKEIEEAFETSARGGN-AIKVMFNL 367

gb|AAL23440.1| Sorbitol Dehydrogenase [Malus x domestica]
(368 aa)

Score: 360 bits (925), Expect: 2.63442e-98
Length: 353, Idn/Pos/Gap = 175/246/4 (49%/69%/1%)

Query:  19 EKANPCGVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDP  78
           E+ N    LV    ++++   +PA  P +VR++++ VGICGSD+HY     CG F++ DP
Sbjct:  19 EQENMAAWLVDVNTIKILPFKLPAIGPNDVRIRIKAVGICGSDIHYLKTMKCGDFQVKDP  78

Query:  79 MIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPV 138
           M+IGHE AG+V+ +G+ V  L  GDRVA+EPG+ C +CQ+C+ GRYNLCP++KFFATPPV
Sbjct:  79 MVIGHECAGIVDKVGSEVKHLVPGDRVAVEPGISCARCQQCKGGRYNLCPDMKFFATPPV 138

Query: 139 DGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIG 198
            GSLA  + HPA  C++LPE+VSLEEGAMCEPLSV VHA RRA     + VL++GAGPIG
Sbjct: 139 HGSLANQIVHPADLCFKLPENVSLEEGAMCEPLSVGVHACRRANVDPETTVLIIGAGPIG 198

Query: 199 LLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAV-INTRDLDEHDAALVVQQALDGA 257
           L++ + A+AFGA  IV+ D+DD+RLA A++    +AV ++T+  D  D    +++A+  +
Sbjct: 199 LVSVLAARAFGAPRIVIVDMDDKRLAMAKSLGADEAVKVSTKMEDLDDEVAEIKEAMI-S 257

Query: 258 QADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSN 317
           + D+  DC G   T+   ++  RPGG++CLVGMG   M VPL  A++RE+D+ GVFRY  
Sbjct: 258 EVDVTFDCVGFNKTVSTGLNATRPGGKVCLVGMGHGVMTVPLTPAAAREVDVVGVFRYQK 317

Query: 318 TYPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLTI 370
           T+P C+  L SG+++VKPLITHRF G  E  +E AF T+    N A+KVM  +
Sbjct: 318 TWPLCLEFLRSGKIDVKPLITHRF-GFTEKEVEEAFATSARGGN-AIKVMFKL 368

gb|AAP69753.1| NAD-dependent sorbitol dehydrogenase 9 [Malus x domestica]
(368 aa)

Score: 359 bits (922), Expect: 5.67623e-98
Length: 353, Idn/Pos/Gap = 175/245/4 (49%/69%/1%)

Query:  19 EKANPCGVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDP  78
           E+ N    LV    ++++   +P+  P +VR++++ VGICGSDVHY     C  F + +P
Sbjct:  19 EQENMAAWLVDVNTIKILPFKLPSIGPNDVRIRIKAVGICGSDVHYLKTMKCADFEVKEP  78

Query:  79 MIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPV 138
           M+IGHE AG+V+ +G+ V  L  GDRVA+EPG+ C +CQ+C+ GRYNLCP++KFFATPPV
Sbjct:  79 MVIGHECAGIVDKVGSEVKHLVPGDRVAVEPGISCARCQQCKGGRYNLCPDMKFFATPPV 138

Query: 139 DGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIG 198
            GSLA  + HPA  C++LPE+VSLEEGAMCEPLSV VHA RRA     + VL++GAGPIG
Sbjct: 139 HGSLANQIVHPADLCFKLPENVSLEEGAMCEPLSVGVHACRRANVGPETTVLIIGAGPIG 198

Query: 199 LLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAV-INTRDLDEHDAALVVQQALDGA 257
           L++ + A+AFGA  IV+ D+DD+RLA A++    +AV ++T+  D  D    +++A+  +
Sbjct: 199 LVSVLTARAFGAPRIVIVDMDDKRLAMAKSLGADEAVKVSTKMEDLDDEVAEIKKAMI-S 257

Query: 258 QADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSN 317
           + D+  DC G   TM   ++  RPGG++CLVGMG   M VPL  A++RE+D+ GVFRY N
Sbjct: 258 EVDVTFDCVGFNKTMSTGLNATRPGGKVCLVGMGHGVMTVPLTPAAAREVDVVGVFRYQN 317

Query: 318 TYPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLTI 370
           T+P C+  L SG+++VKPLITHRF G  E  +E AF T+    N A+KVM  +
Sbjct: 318 TWPLCLEFLRSGKIDVKPLITHRF-GFTEKEVEEAFATSARGGN-AIKVMFKL 368

gb|AAK71492.1| sorbitol dehydrogenase [Prunus cerasus]
(368 aa)

Score: 359 bits (922), Expect: 5.77174e-98
Length: 371, Idn/Pos/Gap = 180/248/9 (48%/66%/2%)

Query:   1 MSEMETELEESDAGSVLNEKANPCGVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGS  60
           MS     LE  D      E+ N    LV    L++    +P   P +VR++++ VGICGS
Sbjct:   6 MSSQGGALEPMDG-----EQENMAAWLVGVNTLKIQPFKLPTVGPNDVRVKIKAVGICGS  60

Query:  61 DVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCR 120
           DVHY     C  F + +PM+IGHE AG+V+ +G+ V +L  GDRVALEPG+ C +C++C+
Sbjct:  61 DVHYLKTMKCADFIVQEPMVIGHECAGIVDEVGSMVKNLLPGDRVALEPGISCWRCEQCK 120

Query: 121 EGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRR 180
            GRYNLCP++KFFATPPV GSLA  + HPA  C++LPE+VSLEEGAMCEPLSV VHA RR
Sbjct: 121 GGRYNLCPDMKFFATPPVHGSLANQIVHPADLCFKLPENVSLEEGAMCEPLSVGVHACRR 180

Query: 181 AGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAV-INTR 239
           A     + VLV+GAGPIGL++ + A+AFGA+ IV+ D+DD RL+ A++    D+V ++T 
Sbjct: 181 ANIGPETNVLVIGAGPIGLVSVLSARAFGAARIVIVDVDDERLSIAKSLGADDSVKVSTN 240

Query: 240 DLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPL 299
             D  +    + +A+ G   D++ DC G   TM  A+   RPGG++CLVGMG   M VPL
Sbjct: 241 PQDLENEVSKISKAMRGG-VDVSFDCVGFNKTMSTALSATRPGGKVCLVGMGHGVMTVPL 299

Query: 300 VDASSREIDIFGVFRYSNTYPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTA 359
             A++RE+D+ G+FRY NT+P C+  L +G+++VKPLITHRF G  +  +E AFET+   
Sbjct: 300 TPAAAREVDVVGIFRYKNTWPLCLEFLRTGKIDVKPLITHRF-GFTQKEIEEAFETSARG 358

Query: 360 ANGAVKVMLTI 370
            N A+KVM  +
Sbjct: 359 GN-AIKVMFNL 368

gb|AAW33814.1| sorbitol dehydrogenase [Malus x domestica]
(368 aa)

Score: 359 bits (922), Expect: 7.05138e-98
Length: 353, Idn/Pos/Gap = 175/245/4 (49%/69%/1%)

Query:  19 EKANPCGVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDP  78
           E+ N    LV    ++++   +P+  P +VR++++ VGICGSDVHY     C  F + +P
Sbjct:  19 EQENMAAWLVDVNTIKILPFKLPSIGPNDVRIRIKAVGICGSDVHYLKTMKCADFEVKEP  78

Query:  79 MIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPV 138
           M+IGHE AG+V+ +G+ V  L  GDRVA+EPG+ C +CQ+C+ GRYNLCP++KFFATPPV
Sbjct:  79 MVIGHECAGIVDKVGSEVKHLVPGDRVAVEPGISCARCQQCKGGRYNLCPDMKFFATPPV 138

Query: 139 DGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIG 198
            GSLA  + HPA  C++LPE+VSLEEGAMCEPLSV VHA RRA     + VL++GAGPIG
Sbjct: 139 HGSLANQIVHPADLCFKLPENVSLEEGAMCEPLSVGVHACRRANVGPETTVLIIGAGPIG 198

Query: 199 LLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAV-INTRDLDEHDAALVVQQALDGA 257
           L++ + A+AFGA  IV+ D+DD+RLA A++    +AV ++T+  D  D    +++A+  +
Sbjct: 199 LVSVLAARAFGAPRIVIVDMDDKRLAMAKSLGADEAVKVSTKMEDLDDEVAEIKEAMI-S 257

Query: 258 QADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSN 317
           + D+  DC G   TM   ++  RPGG++CLVGMG   M VPL  A++RE+D+ GVFRY N
Sbjct: 258 EVDVTFDCVGFNKTMSTGLNATRPGGKVCLVGMGHGVMTVPLTPAAAREVDVVGVFRYQN 317

Query: 318 TYPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLTI 370
           T+P C+  L SG+++VKPLITHRF G  E  +E AF T+    N A+KVM  +
Sbjct: 318 TWPLCLEFLRSGKIDVKPLITHRF-GFTEKEVEEAFATSARGGN-AIKVMFKL 368

gb|AAL37294.1| sorbitol dehydrogenase [Malus x domestica]
(368 aa)

Score: 356 bits (914), Expect: 4.92701e-97
Length: 354, Idn/Pos/Gap = 176/243/6 (49%/68%/1%)

Query:  19 EKANPCGVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDP  78
           E+ N    LV    ++++   +PA  P +VR++++ VGICGSD+HY     CG F++ DP
Sbjct:  19 EQENMAVWLVDVNTIKILPFKLPAIGPNDVRIRIKAVGICGSDIHYLKTMKCGDFQVKDP  78

Query:  79 MIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPV 138
           M+IGHE AG+V+ +G+ V  L  GDRVA+EPG+ C  CQ+C+ GRYNLC ++KFFATPPV
Sbjct:  79 MVIGHECAGIVDKVGSKVKHLVPGDRVAVEPGISCAHCQQCKGGRYNLCFDMKFFATPPV 138

Query: 139 DGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIG 198
            GSLA  + HPA  C++LPE+VSLEEGAMCEPLSV VH  RRA     + VL++GAGPIG
Sbjct: 139 HGSLANQIVHPADLCFKLPENVSLEEGAMCEPLSVGVHPFRRANVGPETTVLIVGAGPIG 198

Query: 199 LLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAV--INTRDLDEHDAALVVQQALDG 256
           L++ + A+AFGA  IV+ D+DDRRLA A++  G D    ++T+  D  D    +++A+ G
Sbjct: 199 LVSVLAARAFGAPRIVIVDMDDRRLAMAKS-LGPDGTVKVSTKMEDLDDELAKIKEAM-G 256

Query: 257 AQADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYS 316
           ++ D+  DC G   TM   ++  RPGG++CLVGMG     VPL  A++RE+D+ GVF Y 
Sbjct: 257 SEVDVTFDCVGFNKTMSTGLNATRPGGKVCLVGMGHGVTTVPLTPAAAREVDVVGVFAYK 316

Query: 317 NTYPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLTI 370
           NT+P C+  L SG+++VKPLITHRF G  E  +E AF T+    N A+KVM T+
Sbjct: 317 NTWPLCLEFLRSGKIDVKPLITHRF-GFTEKEVEEAFATSARGGN-AIKVMFTL 368

gb|AAM91782.1| putative sorbitol dehydrogenase [Arabidopsis thaliana]
gb|AAK43976.1| putative sorbitol dehydrogenase [Arabidopsis thaliana]
dbj|BAB11045.1| sorbitol dehydrogenase-like protein [Arabidopsis thaliana]
ref|NP_974925.1| sorbitol dehydrogenase, putative / L-iditol 2-dehydrogenase, putative [Arabidopsis thaliana]
ref|NP_200010.1| sorbitol dehydrogenase, putative / L-iditol 2-dehydrogenase, putative [Arabidopsis thaliana]
(364 aa)

Score: 353 bits (907), Expect: 3.03765e-96
Length: 353, Idn/Pos/Gap = 181/238/4 (51%/67%/1%)

Query:  19 EKANPCGVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDP  78
           E+ N    LV    L++    +P+  P +VR++M+ VGICGSDVHY     C  F + +P
Sbjct:  15 EEENMAAWLVGINTLKIQPFLLPSVGPHDVRVRMKAVGICGSDVHYLKTMRCADFVVKEP  74

Query:  79 MIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPV 138
           M+IGHE AG++E +G  V  L VGDRVALEPG+ C +C  CREGRYNLCP +KFFATPPV
Sbjct:  75 MVIGHECAGIIEEVGEEVKHLVVGDRVALEPGISCWRCNLCREGRYNLCPEMKFFATPPV 134

Query: 139 DGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIG 198
            GSLA  V HPA  C++LPE+VSLEEGAMCEPLSV VHA RRA     + VLV+GAGPIG
Sbjct: 135 HGSLANQVVHPADLCFKLPENVSLEEGAMCEPLSVGVHACRRAEVGPETNVLVMGAGPIG 194

Query: 199 LLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVIN-TRDLDEHDAALVVQQALDGA 257
           L+  + A+AF    IV+ D+D+ RLA A+   GAD ++  T +L++  + +   Q   G+
Sbjct: 195 LVTMLAARAFSVPRIVIVDVDENRLAVAK-QLGADEIVQVTTNLEDVGSEVEQIQKAMGS 253

Query: 258 QADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSN 317
             D+  DCAG   TM  A+   R GG++CLVGMG   M VPL  A++RE+D+ GVFRY N
Sbjct: 254 NIDVTFDCAGFNKTMSTALAATRCGGKVCLVGMGHGIMTVPLTPAAAREVDVVGVFRYKN 313

Query: 318 TYPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLTI 370
           T+P C+  L SG+++VKPLITHRF G  +  +E AFET+   +N A+KVM  +
Sbjct: 314 TWPLCLEFLTSGKIDVKPLITHRF-GFSQKEVEDAFETSARGSN-AIKVMFNL 364

gb|AAP69751.1| NAD-dependent sorbitol dehydrogenase 2 [Malus x domestica]
(322 aa)

Score: 353 bits (907), Expect: 3.41404e-96
Length: 317, Idn/Pos/Gap = 170/229/5 (53%/72%/1%)

Query:  40 VPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSL  99
           +PA  P +VR++++ VGICGSD+HY     CG F++ DPM+IGHE AG+V+ +G+ V  L
Sbjct:   6 LPAIGPNDVRIRIKAVGICGSDIHYLKTMKCGDFQVKDPMVIGHECAGIVDKVGSEVKHL  65

Query: 100 QVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPES 159
             GDRVA+EPG+ C  CQ+C+ GRYNLCP++KFFATPPV GSLA  + HPA  C++LPE+
Sbjct:  66 VPGDRVAVEPGISCAHCQQCKGGRYNLCPDMKFFATPPVHGSLANQIVHPADLCFKLPEN 125

Query: 160 VSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDID 219
           VSLEEGAMCEPLSV VHA RRA     + VL++GAGPIGL++ + A+AFGA  IV+ D+D
Sbjct: 126 VSLEEGAMCEPLSVGVHACRRANVGPETTVLIVGAGPIGLVSVLAARAFGAPRIVIVDMD 185

Query: 220 DRRLAFAETHAGADAV--INTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMH 277
           DRRLA A++  GAD    ++T+  D  D    +++A+ G++ D+  DC G   TM   ++
Sbjct: 186 DRRLAMAKS-LGADGTVKVSTKMEDLDDEVAKIKEAM-GSEVDVTFDCVGFNKTMSTGLN 243

Query: 278 VVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASGRVNVKPLI 337
             RPGG++CLVGMG   M VPL  A++RE+D+ GVFRY NT+P C+  L SG+++VKPLI
Sbjct: 244 ATRPGGKVCLVGMGHGVMTVPLTPAAAREVDVVGVFRYKNTWPLCLEFLRSGKIDVKPLI 303

Query: 338 THRFMGLEESSLEAAFE 354
           THRF G  E  +E A E
Sbjct: 304 THRF-GFTEKEVEEALE 319

gb|AAM62446.1| sorbitol dehydrogenase-like protein [Arabidopsis thaliana]
(364 aa)

Score: 353 bits (907), Expect: 3.52991e-96
Length: 353, Idn/Pos/Gap = 181/238/4 (51%/67%/1%)

Query:  19 EKANPCGVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDP  78
           E+ N    LV    L++    +P+  P +VR++M+ VGICGSDVHY     C  F + +P
Sbjct:  15 EEENMAAWLVGINTLKIQPFLLPSVGPHDVRVRMKAVGICGSDVHYLKTMRCADFVVKEP  74

Query:  79 MIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPV 138
           M+IGHE AG++E +G  V  L VGDRVALEPG+ C +C  CREGRYNLCP +KFFATPPV
Sbjct:  75 MVIGHECAGIIEEVGEEVKHLVVGDRVALEPGISCWRCNLCREGRYNLCPEMKFFATPPV 134

Query: 139 DGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIG 198
            GSLA  V HPA  C++LPE+VSLEEGAMCEPLSV VHA RRA     + VLV+GAGPIG
Sbjct: 135 HGSLANQVVHPADLCFKLPENVSLEEGAMCEPLSVGVHACRRAEVGPETNVLVMGAGPIG 194

Query: 199 LLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVIN-TRDLDEHDAALVVQQALDGA 257
           L+  + A+AF    IV+ D+D+ RLA A+   GAD ++  T +L++  + +   Q   G+
Sbjct: 195 LVTMLAAQAFSVPRIVIVDVDENRLAVAK-QLGADEIVQVTTNLEDVGSEVEQIQKAMGS 253

Query: 258 QADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSN 317
             D+  DCAG   TM  A+   R GG++CLVGMG   M VPL  A++RE+D+ GVFRY N
Sbjct: 254 NIDVTFDCAGFNKTMSTALAATRCGGKVCLVGMGHGIMTVPLTPAAAREVDVVGVFRYKN 313

Query: 318 TYPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLTI 370
           T+P C+  L SG+++VKPLITHRF G  +  +E AFET+   +N A+KVM  +
Sbjct: 314 TWPLCLEFLTSGKIDVKPLITHRF-GFSQKEVEDAFETSARGSN-AIKVMFNL 364

dbj|BAD44664.1| sorbitol dehydrogenase-like protein [Arabidopsis thaliana]
(364 aa)

Score: 353 bits (906), Expect: 4.31252e-96
Length: 353, Idn/Pos/Gap = 181/238/4 (51%/67%/1%)

Query:  19 EKANPCGVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDP  78
           E+ N    LV    L++    +P+  P +VR++M+ VGICGSDVHY     C  F + +P
Sbjct:  15 EEENMAAWLVGINTLKIQPFLLPSVGPHDVRVRMKAVGICGSDVHYLKTMICADFVVKEP  74

Query:  79 MIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPV 138
           M+IGHE AG++E +G  V  L VGDRVALEPG+ C +C  CREGRYNLCP +KFFATPPV
Sbjct:  75 MVIGHECAGIIEEVGEEVKHLVVGDRVALEPGISCWRCNLCREGRYNLCPEMKFFATPPV 134

Query: 139 DGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIG 198
            GSLA  V HPA  C++LPE+VSLEEGAMCEPLSV VHA RRA     + VLV+GAGPIG
Sbjct: 135 HGSLANQVVHPADLCFKLPENVSLEEGAMCEPLSVGVHACRRAEVGPETNVLVMGAGPIG 194

Query: 199 LLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVIN-TRDLDEHDAALVVQQALDGA 257
           L+  + A+AF    IV+ D+D+ RLA A+   GAD ++  T +L++  + +   Q   G+
Sbjct: 195 LVTMLAARAFSVPRIVIVDVDENRLAVAK-QLGADEIVQVTTNLEDVGSEVEQIQKAMGS 253

Query: 258 QADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSN 317
             D+  DCAG   TM  A+   R GG++CLVGMG   M VPL  A++RE+D+ GVFRY N
Sbjct: 254 NIDVTFDCAGFNKTMSTALAATRCGGKVCLVGMGHGIMTVPLTPAAAREVDVVGVFRYKN 313

Query: 318 TYPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLTI 370
           T+P C+  L SG+++VKPLITHRF G  +  +E AFET+   +N A+KVM  +
Sbjct: 314 TWPLCLEFLTSGKIDVKPLITHRF-GFSQKEVEDAFETSARGSN-AIKVMFNL 364

gb|AAL37296.1| sorbitol dehydrogenase [Malus x domestica]
(367 aa)

Score: 348 bits (894), Expect: 1.18391e-94
Length: 353, Idn/Pos/Gap = 174/242/5 (49%/68%/1%)

Query:  19 EKANPCGVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDP  78
           E+ N    LV    ++++   +PA  P +VR++++ V ICGSDVHY     C  F + +P
Sbjct:  19 EQENMAVWLVDVNTIKILPFKLPAIGPNDVRIRIKAVVICGSDVHYLKTMKCADFEVKEP  78

Query:  79 MIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPV 138
           M+IGHE AG+V+ +G+ V  L  GDRV  EPG+ C +CQ+C+ GRYNLCP++KFFATPPV
Sbjct:  79 MVIGHECAGIVDTVGSEVKHLVPGDRVG-EPGISCARCQQCKGGRYNLCPDMKFFATPPV 137

Query: 139 DGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIG 198
            GSLA  + HPA  C++LPE+VSLEEGAMCEPLSV VHA RRA     + VL++GAGPIG
Sbjct: 138 HGSLANQIVHPADLCFKLPENVSLEEGAMCEPLSVGVHACRRANVGPETSVLIIGAGPIG 197

Query: 199 LLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAV-INTRDLDEHDAALVVQQALDGA 257
           L++ + A+AFGA  IV+ D+DD+RLA A++    +AV ++T+  D  D    +++A+  +
Sbjct: 198 LVSVLAARAFGAPRIVIVDMDDKRLAMAKSLGADEAVKVSTKMEDLDDRVAEIKKAMI-S 256

Query: 258 QADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSN 317
           + D+  DC G   TM   ++  RPGG++CLVGMG   M VPL  A++RE+D+ GVFRY N
Sbjct: 257 EVDVTFDCVGFNKTMSTGLNATRPGGKVCLVGMGHGVMTVPLTPAAAREVDVVGVFRYQN 316

Query: 318 TYPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLTI 370
           T+P C+  L SG+++VKPLITHRF G  E  +E AF T+    N A+KVM  +
Sbjct: 317 TWPLCLEFLRSGKIDVKPLITHRF-GFTEKEVEEAFATSARGGN-AIKVMFKL 367

gb|AAL37295.1| sorbitol dehydrogenase [Malus x domestica]
(368 aa)

Score: 348 bits (893), Expect: 1.30858e-94
Length: 353, Idn/Pos/Gap = 171/240/4 (48%/67%/1%)

Query:  19 EKANPCGVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDP  78
           EK N    LV    ++++   +P   P +V+++++ VGICGSDVHY     C  F + +P
Sbjct:  19 EKENMAAWLVDVNTIKILPFKLPTIGPNDVQIRIKAVGICGSDVHYLKTMKCADFEVKEP  78

Query:  79 MIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPV 138
           M+IGH+ AG+V+ +G+ V  L  GDRVA+EPG+ C  CQ+C+ GRYNLCP++KFFATPPV
Sbjct:  79 MVIGHQCAGIVDKVGSEVKHLVPGDRVAVEPGISCAHCQQCKGGRYNLCPDMKFFATPPV 138

Query: 139 DGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIG 198
            G+LA  +  PA  C++LPE+VSLEEGAMCEPLSV VHA RRA     + VL++GAGPIG
Sbjct: 139 HGALANQIVDPADLCFKLPENVSLEEGAMCEPLSVGVHACRRANVGPETTVLIVGAGPIG 198

Query: 199 LLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVIN-TRDLDEHDAALVVQQALDGA 257
           L++ + A+AFGA  IV+ D+D +RLA A++  GAD  +  +R +++ D  +   +   GA
Sbjct: 199 LVSVLAARAFGAPRIVIVDMDSKRLAVAKS-LGADGTVKVSRKMEDLDDEVAKIKETMGA 257

Query: 258 QADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSN 317
           + D+  DC G   TM   ++  RPGG++CLVGMG S M VPL  A++RE+D+ GVFR  N
Sbjct: 258 EVDVTFDCVGFNKTMSTGLNATRPGGKVCLVGMGHSMMTVPLTAAAAREVDVVGVFRCKN 317

Query: 318 TYPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLTI 370
           T+P C+  L SG+++VKPLITHRF G  E  +E AF T+    + A+KVM  +
Sbjct: 318 TWPLCLEFLRSGKIDVKPLITHRF-GFTEKEVEEAFATSARGGD-AIKVMFNL 368

gb|AAP69755.1| NAD-dependent sorbitol dehydrogenase 8 [Malus x domestica]
(321 aa)

Score: 344 bits (882), Expect: 2.53044e-93
Length: 316, Idn/Pos/Gap = 162/226/2 (51%/71%/0%)

Query:  40 VPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSL  99
           +PA  P +VR++++ VGICGSDVHY     C  F + +PM+IGHE AG+V+ +G+ V  L
Sbjct:   6 LPAIGPNDVRIRIKAVGICGSDVHYLKTMKCADFEVKEPMVIGHECAGIVDKVGSEVKHL  65

Query: 100 QVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPES 159
             GDRVA+EPG+ C +CQ+C+ GRYNLCP++KFFATPPV GSLA  + HPA  C++LP++
Sbjct:  66 VPGDRVAVEPGISCARCQQCKGGRYNLCPDMKFFATPPVHGSLANQIVHPADLCFKLPKN 125

Query: 160 VSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDID 219
           VSLEEGAMCEPLS+ VHA RRA     + VL+ GAGPIGL++ + A+AFGA  IV+ D+D
Sbjct: 126 VSLEEGAMCEPLSIGVHACRRANVGPETTVLITGAGPIGLVSVLAARAFGAPRIVIVDMD 185

Query: 220 DRRLAFAETHAGADAV-INTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHV 278
           D+RLA A++    + V ++T+  D  D    +++A++ ++ D+  DC G   TM   ++ 
Sbjct: 186 DKRLAMAKSLGADETVKVSTKMEDLDDEVAEIKKAME-SEVDVTFDCVGFNKTMSTGLNA 244

Query: 279 VRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASGRVNVKPLIT 338
            RPGG++CLVGMG   M VPL  A++RE+D+ GVFRY NT+P C+  L SG+++VKPLIT
Sbjct: 245 TRPGGKVCLVGMGHGMMTVPLTPAAAREVDVVGVFRYKNTWPLCLEFLRSGKIDVKPLIT 304

Query: 339 HRFMGLEESSLEAAFE 354
           HRF   E+   EA+ E
Sbjct: 305 HRFGFTEKEVEEASLE 320

gb|AAP69752.1| NAD-dependent sorbitol dehydrogenase 3 [Malus x domestica]
(321 aa)

Score: 342 bits (878), Expect: 7.48634e-93
Length: 319, Idn/Pos/Gap = 167/225/8 (52%/70%/2%)

Query:  40 VPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSL  99
           +PA    +V+++++ VGICGSDVHY  +     F + +PM+IGHE AG+VE +G+ V  L
Sbjct:   6 LPAIGLNDVQIRIKAVGICGSDVHYLKNMKLADFEVKEPMVIGHECAGIVEKVGSDVKHL  65

Query: 100 QVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPES 159
             GDRVA+EPG+ C +CQ+C+ GRYNLCP++KFFATPPV GSLA  + HPA  C++LPE+
Sbjct:  66 VSGDRVAVEPGISCSRCQQCKGGRYNLCPDMKFFATPPVHGSLANQIVHPADLCFKLPEN 125

Query: 160 VSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDID 219
           VSLEEGAMCEPLSV VHA RRA     + VL++GAGPIGL++ + A+AFGA  IV+ D+D
Sbjct: 126 VSLEEGAMCEPLSVGVHACRRANVGPETTVLIVGAGPIGLVSVLAARAFGAPRIVIVDMD 185

Query: 220 DRRLAFAETHAGADAVINT----RDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLA 275
           D+RLA A++  GAD  +       DLD+  A +   +   GA+ D+  DC G   TM   
Sbjct: 186 DKRLAVAKS-LGADGTVKVSAKMEDLDDEVAKI---KETMGAEVDVTFDCVGFNKTMSTG 241

Query: 276 MHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASGRVNVKP 335
           ++  RPGG++CLVGMG S M VPL  A++RE+D+ GVFRY NT+P C+  L SG+++VKP
Sbjct: 242 LNATRPGGKVCLVGMGHSMMTVPLTPAAAREVDVVGVFRYKNTWPLCLEFLRSGKIDVKP 301

Query: 336 LITHRFMGLEESSLEAAFE 354
           LITHRF   E+   EA+ E
Sbjct: 302 LITHRFGFTEKEVEEASLE 320

gb|AAP69756.1| NAD-dependent sorbitol dehydrogenase 7 [Malus x domestica]
(321 aa)

Score: 342 bits (878), Expect: 8.41396e-93
Length: 319, Idn/Pos/Gap = 168/227/8 (52%/71%/2%)

Query:  40 VPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSL  99
           +PA  P +VR++++ VGICGSDVHY     C  F + +PM+IGHE AG+V+ +G+ V  L
Sbjct:   6 LPAIGPNDVRIRIKAVGICGSDVHYLRTMKCADFEVKEPMVIGHECAGIVDKVGSEVKHL  65

Query: 100 QVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPES 159
             GDRVA+EPG+ C + Q+C+ G+YNLCP++KFFATPPV GSLA  + HPA  C++LPE+
Sbjct:  66 VPGDRVAVEPGISCSRRQQCKGGQYNLCPDMKFFATPPVHGSLANQIVHPADLCFKLPEN 125

Query: 160 VSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDID 219
           VSLEEGAMCEPLSV VHA RRA     + VL++GAGPIGL++ + A+AFGA  IV+ D+D
Sbjct: 126 VSLEEGAMCEPLSVGVHACRRANVGPETTVLIVGAGPIGLVSVLAARAFGAPRIVIVDMD 185

Query: 220 DRRLAFAETHAGADAV----INTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLA 275
           DRRLA A++  GAD      I   DLD+  A   +++A+ G++ D+  DC G   TM   
Sbjct: 186 DRRLAMAKS-LGADGTVKVSIKMEDLDDEVAK--IKEAM-GSEVDVTFDCVGFNKTMSTG 241

Query: 276 MHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASGRVNVKP 335
           ++  RPGG++CLVGMG   M VPL  A++RE+D+ GVFRY NT+P C+  L SG+++VKP
Sbjct: 242 LNATRPGGKVCLVGMGHGVMTVPLTPAAAREVDVVGVFRYKNTWPLCLEFLRSGKIDVKP 301

Query: 336 LITHRFMGLEESSLEAAFE 354
           LITHRF   E+   EA+ E
Sbjct: 302 LITHRFGFTEKEVEEASLE 320

ref|XP_507318.1| PREDICTED P0623F08.37 gene product [Oryza sativa (japonica cultivar-group)]
ref|XP_483619.1| putative sorbitol dehydrogenase [Oryza sativa (japonica cultivar-group)]
dbj|BAD09736.1| putative sorbitol dehydrogenase [Oryza sativa (japonica cultivar-group)]
dbj|BAD09222.1| putative sorbitol dehydrogenase [Oryza sativa (japonica cultivar-group)]
(369 aa)

Score: 342 bits (876), Expect: 1.41145e-92
Length: 351, Idn/Pos/Gap = 175/239/6 (49%/68%/1%)

Query:  22 NPCGVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMII  81
           N    LV    L++M   +P   P +VR++M+ VGICGSDVHY        F + +PM+I
Sbjct:  23 NMAAWLVAKNTLKIMPFKLPPVGPYDVRVRMKAVGICGSDVHYLREMRIAHFVVKEPMVI  82

Query:  82 GHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGS 141
           GHE AGV+E +G+GVT L VGDRVALEPG+ C +C+ C+ GRYNLC ++KFFATPPV GS
Sbjct:  83 GHECAGVIEEVGSGVTHLAVGDRVALEPGISCWRCRHCKGGRYNLCEDMKFFATPPVHGS 142

Query: 142 LARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLN 201
           LA  + HP   C++LPE+VSLEEGAMCEPLSV VHA RRA     + VL++GAGPIGL+ 
Sbjct: 143 LANQIVHPGDLCFKLPENVSLEEGAMCEPLSVGVHACRRADVGPETGVLIMGAGPIGLVT 202

Query: 202 CMVAKAFGASIIVVTDIDDRRLAFAETHAGADAV--INTRDLDEHDAALVVQQALDGAQA 259
            + A+AFGA+ +V+ D+D+ RL+ A +  GADA   ++ R  D  +    ++ A+ G   
Sbjct: 203 LLAARAFGATRVVIVDVDEHRLSVARS-LGADAAVRVSARAEDVGEEVERIRAAM-GGDI 260

Query: 260 DIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTY 319
           D++LDCAG   T+  A+   R GG++CLVGMG + M VPL  A+ RE+D+ G+FRY +T+
Sbjct: 261 DVSLDCAGFSKTVATALEATRGGGKVCLVGMGHNEMTVPLTSAAIREVDVVGIFRYKDTW 320

Query: 320 PTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLTI 370
           P CI  L SG+++VKPLITHRF G  +  +E AFE +    + A+KVM  +
Sbjct: 321 PLCIEFLRSGKIDVKPLITHRF-GFSQEDVEEAFEVSARGRD-AIKVMFNL 369

gb|AAP69757.1| NAD-dependent sorbitol dehydrogenase 6 [Malus x domestica]
(319 aa)

Score: 337 bits (865), Expect: 2.72936e-91
Length: 315, Idn/Pos/Gap = 164/225/5 (52%/71%/1%)

Query:  40 VPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSL  99
           +PA  P +VR++++ VGICGSDVHY     C  F + +PM+IGHE AG+V+ +G+ V  L
Sbjct:   6 LPAIGPNDVRIRIKAVGICGSDVHYLRTMKCADFEVKEPMVIGHECAGIVDKVGSEVKHL  65

Query: 100 QVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPES 159
             GDRVA+EPG+ C +CQ+C+ G+YNLCP++KFFATPPV GSLA  + HPA  C++LPE+
Sbjct:  66 VPGDRVAVEPGISCSRCQQCKGGQYNLCPDMKFFATPPVHGSLANQIVHPADLCFKLPEN 125

Query: 160 VSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDID 219
           VSLEEGAMCEPLSV VHA RRA     + VL++GAGPIGL++ + A AFGA  IV+ D+D
Sbjct: 126 VSLEEGAMCEPLSVGVHACRRANVGPETTVLIIGAGPIGLVSVLAALAFGAPRIVIVDMD 185

Query: 220 DRRLAFAETHAGADAV--INTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMH 277
           D+RLA A++  GAD    ++T+  D  D    +++A++ ++ D+  DC G   TM   ++
Sbjct: 186 DKRLAMAKS-LGADGTVKVSTKMEDLDDEVAKIKEAME-SEVDVTFDCVGFNKTMSTGLN 243

Query: 278 VVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASGRVNVKPLI 337
             RPGG++CLVGMG   M VPL  A++RE+D+ GVFR  NT+P C+  L SG+++VKPLI
Sbjct: 244 ATRPGGKVCLVGMGHGMMTVPLTPAAAREVDVVGVFRCKNTWPLCLEFLRSGKIDVKPLI 303

Query: 338 THRFMGLEESSLEAA 352
           THRF G  E  +E A
Sbjct: 304 THRF-GFTEKEVEEA 317

dbj|BAA95897.1| NAD-dependent sorbitol dehydrogenase [Eriobotrya japonica]
(371 aa)

Score: 337 bits (863), Expect: 3.94004e-91
Length: 356, Idn/Pos/Gap = 169/240/13 (47%/67%/3%)

Query:  19 EKANPCGVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDP  78
           ++ N    L+  + L++    +P   P +VR++++ VGICGSDVH++ +  C  F + +P
Sbjct:  25 QQENMAAWLLGVKNLKIQPYKLPNLGPHDVRVRLKAVGICGSDVHHFKNMRCVDFIVKEP  84

Query:  79 MIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPV 138
           M+IGHE AG++E +G+ V  L  GDRVALEPG+ C +C  C++GRYNLC  +KFF +PP 
Sbjct:  85 MVIGHECAGIIEEVGSEVEDLVPGDRVALEPGISCKRCNLCKQGRYNLCRKMKFFGSPPN 144

Query: 139 DGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIG 198
           +G LA  V HP   C++LP++VSLEEGAMCEPLSV +HA RRA     + VLV+GAGPIG
Sbjct: 145 NGCLANQVVHPGDLCFKLPDNVSLEEGAMCEPLSVGIHACRRANVCQETNVLVVGAGPIG 204

Query: 199 LLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVI----NTRDLDEHDAALVVQQAL 254
           L+  + A+AFGA  IV+ D++D RL+ A++  GAD V+    N  DL E  A   +Q+ L
Sbjct: 205 LVTLLAARAFGAPRIVIADVNDERLSIAKS-LGADEVVKVSTNIEDLAEEVA--TIQKVL 261

Query: 255 DGAQADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFR 314
           +    D++ DCAG + T+  A+   RPGG++CLVGMG   M +PL   ++REID+ G+FR
Sbjct: 262 ENG-VDVSFDCAGFDKTITTALSATRPGGKVCLVGMGQREMTLPL---ATREIDVIGIFR 317

Query: 315 YSNTYPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLTI 370
           Y NT+P C+  L SG+++VKPLITHRF G  +  +E AFET+    N A+KVM  +
Sbjct: 318 YQNTWPLCLEFLRSGKIDVKPLITHRF-GFSQKEVEEAFETSARGGN-AIKVMFNL 371

dbj|BAA36481.2| NAD-dependent sorbitol dehydrogenase [Malus x domestica]
(371 aa)

Score: 336 bits (861), Expect: 7.12491e-91
Length: 356, Idn/Pos/Gap = 170/238/13 (47%/66%/3%)

Query:  19 EKANPCGVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDP  78
           ++ N    L+  + L++    +P   P +VR+++R VGICGSDVH++ +  C  F + +P
Sbjct:  25 QQENMAAWLLGVKNLKIQPYKLPNLGPHDVRVRLRAVGICGSDVHHFKNMRCVDFIVKEP  84

Query:  79 MIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPV 138
           M+IGHE AG++E +G+ V  L  GDRVALEPG+ C +C  C++GRYNLC  +KFF +PP 
Sbjct:  85 MVIGHECAGIIEEVGSEVEHLVPGDRVALEPGISCKRCNLCKQGRYNLCRKMKFFGSPPN 144

Query: 139 DGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIG 198
           +G LA  V HP   C++LP++VSLEEGAMCEPLSV +HA RRA     + VLV+GAGPIG
Sbjct: 145 NGCLANQVVHPGDLCFKLPDNVSLEEGAMCEPLSVGIHACRRANVCQETNVLVVGAGPIG 204

Query: 199 LLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVI----NTRDLDEHDAALVVQQAL 254
           L+  + A+AFGA  IV+ D++D RL  A++  GADAV+    N  D+ E  A   +Q+ L
Sbjct: 205 LVTLLAARAFGAPRIVIADVNDERLLIAKS-LGADAVVKVSTNIEDVAEEVAK--IQKVL 261

Query: 255 DGAQADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFR 314
           +    D+  DCAG   T+  A+   RPGG++CLVGMG   M +PL   ++REID+ G+FR
Sbjct: 262 ENG-VDVTFDCAGFNKTITTALSATRPGGKVCLVGMGQREMTLPL---ATREIDVIGIFR 317

Query: 315 YSNTYPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLTI 370
           Y NT+P C+  L SG+++VKPLITHRF G  +  +E AFET+    N A+KVM  +
Sbjct: 318 YQNTWPLCLEFLRSGKIDVKPLITHRF-GFSQKEVEEAFETSARGGN-AIKVMFNL 371

gb|AAW33813.1| sorbitol dehydrogenase [Malus x domestica]
(371 aa)

Score: 335 bits (859), Expect: 1.32108e-90
Length: 356, Idn/Pos/Gap = 169/238/13 (47%/66%/3%)

Query:  19 EKANPCGVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDP  78
           ++ N    L+  + L++    +P   P +VR++++ VGICGSDVH++ +  C  F + +P
Sbjct:  25 QQENMAAWLLGVKNLKIQPYKLPNLGPHDVRVRLKAVGICGSDVHHFKNMRCVDFIVKEP  84

Query:  79 MIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPV 138
           M+IGHE AG++E +G+ V  L  GDRVALEPG+ C +C  C++GRYNLC  +KFF +PP 
Sbjct:  85 MVIGHECAGIIEEVGSEVEDLVPGDRVALEPGISCKRCNLCKQGRYNLCRKMKFFGSPPN 144

Query: 139 DGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIG 198
           +G LA  V HP   C++LP++VSLEEGAMCEPLSV +HA RRA     + VLV+GAGPIG
Sbjct: 145 NGCLANQVVHPGDLCFKLPDNVSLEEGAMCEPLSVGIHACRRANVCQETNVLVVGAGPIG 204

Query: 199 LLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVI----NTRDLDEHDAALVVQQAL 254
           L+  + A+AFGA  IV+ D++D RL  A++  GADAV+    N  D+ E  A   +Q+ L
Sbjct: 205 LVTLLAARAFGAPRIVIADVNDERLLIAKS-LGADAVVKVSTNIEDVAEEVAK--IQKVL 261

Query: 255 DGAQADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFR 314
           +    D+  DCAG   T+  A+   RPGG++CLVGMG   M +PL   ++REID+ G+FR
Sbjct: 262 ENG-VDVTFDCAGFNKTITTALSATRPGGKVCLVGMGQREMTLPL---ATREIDVIGIFR 317

Query: 315 YSNTYPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLTI 370
           Y NT+P C+  L SG+++VKPLITHRF G  +  +E AFET+    N A+KVM  +
Sbjct: 318 YQNTWPLCLEFLRSGKIDVKPLITHRF-GFSQKEVEEAFETSARGGN-AIKVMFNL 371

ref|NP_477348.1| CG1982-PA [Drosophila melanogaster]
gb|AAF54080.1| CG1982-PA [Drosophila melanogaster]
gb|AAD19792.1| sorbitol dehydrogenase [Drosophila melanogaster]
gb|AAD00902.1| sorbitol dehydrogenase [Drosophila melanogaster]
(360 aa)

Score: 335 bits (858), Expect: 1.89124e-90
Length: 351, Idn/Pos/Gap = 180/243/4 (51%/69%/1%)

Query:  20 KANPCGVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPM  79
           K N   VL    ++R+  R +P  A  EV L M  VGICGSDVHY  HG  G F L  PM
Sbjct:   3 KDNLTAVLHGIEDMRLEQRPIPEIADDEVLLAMDSVGICGSDVHYLAHGRIGDFVLTKPM  62

Query:  80 IIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVD 139
           IIGHESAGVV  LG  VT+L+VGDRVA+EPGVPC +C  C++G+YNLCP + F ATPP D
Sbjct:  63 IIGHESAGVVAKLGKKVTTLKVGDRVAIEPGVPCRKCDHCKQGKYNLCPGMVFCATPPYD 122

Query: 140 GSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGL 199
           G+L RY  H A +C++LP+ V++EEGA+ EPLSV VHA +RA  T+GS VL+LGAGPIGL
Sbjct: 123 GNLTRYYKHAADFCFKLPDHVTMEEGALLEPLSVGVHACKRAEVTLGSKVLILGAGPIGL 182

Query: 200 LNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQA 259
           +  M A+A GAS I++TD+  +RL  A+       ++  RD    + A++VQ+ + G Q 
Sbjct: 183 VTLMAAQAMGASEILITDLVQQRLDVAKELGATHTLLLKRDQTAEETAVLVQKTM-GGQP 241

Query: 260 DIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTY 319
           D ++DC G ES+ RLA+   R GG + +VGMG++ + +PL++A +RE+DI GVFRY N Y
Sbjct: 242 DKSIDCCGAESSARLAIFATRSGGIVVVVGMGAAEIKLPLINALAREVDIRGVFRYCNDY 301

Query: 320 PTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLTI 370
              +AL+ASG+VNVK L+TH F  ++E++   AFET+R    GA+KVM+ +
Sbjct: 302 AAALALVASGKVNVKRLVTHHF-DIKETA--KAFETSRKGLGGAIKVMIHV 349

gb|AAP69749.1| NAD-dependent sorbitol dehydrogenase 1 [Malus x domestica]
(371 aa)

Score: 332 bits (852), Expect: 8.01007e-90
Length: 356, Idn/Pos/Gap = 167/236/13 (46%/66%/3%)

Query:  19 EKANPCGVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDP  78
           ++ N    L+  + L++    +P   P +VR++++ VGICGSDVH++ +  C  F + +P
Sbjct:  25 QQENMAAWLLGVKNLKIQPYKLPNLGPHDVRVRLKAVGICGSDVHHFKNMRCVDFIVKEP  84

Query:  79 MIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPV 138
           M+IGHE AG++E +G+ V  L  GDRVALEPG+ C +C  C++GRYNLC  +KFF +PP 
Sbjct:  85 MVIGHECAGIIEEVGSEVEDLVPGDRVALEPGISCKRCNLCKQGRYNLCRKMKFFGSPPN 144

Query: 139 DGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIG 198
           +G LA  V HP   C++LP++VSLEEGAMCEPLSV +HA RRA     +  LV+GAGPIG
Sbjct: 145 NGCLANQVVHPGDLCFKLPDNVSLEEGAMCEPLSVGIHACRRANVCQETNALVVGAGPIG 204

Query: 199 LLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVI----NTRDLDEHDAALVVQQAL 254
           L+  + A+AFGA  IV+ D++D RL  A++  GAD V+    N  D+ E  A   +Q+ L
Sbjct: 205 LVTLLAARAFGAPRIVIADVNDERLLIAKS-LGADEVVKVSTNIEDVAEEVAK--IQKVL 261

Query: 255 DGAQADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFR 314
           +    D+  DCAG   T+  A+   RPGG++CLVGMG   M +PL   ++REID+ G+FR
Sbjct: 262 ENG-VDVTFDCAGFNKTITTALSATRPGGKVCLVGMGQREMTLPL---ATREIDVIGIFR 317

Query: 315 YSNTYPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLTI 370
           Y NT+P C+  L SG+++VKPLITHRF G  +  +E AFET+    N A+KVM  +
Sbjct: 318 YQNTWPLCLEFLRSGKIDVKPLITHRF-GFSQKEVEEAFETSARGGN-AIKVMFNL 371

gb|AAD02817.1| NADP(H)-dependent ketose reductase [Bemisia argentifolii]
pdb|1E3J|A Chain A, Ketose Reductase (Sorbitol Dehydrogenase) From Silverleaf Whitefly
(352 aa)

Score: 332 bits (852), Expect: 8.63474e-90
Length: 350, Idn/Pos/Gap = 174/240/8 (49%/68%/2%)

Query:  22 NPCGVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMII  81
           N   VL +  +LR+  R +P P   EV LQM  VGICGSDVHY+ HG    F + DPM+I
Sbjct:   5 NLSAVLYKQNDLRLEQRPIPEPKEDEVLLQMAYVGICGSDVHYYEHGRIADFIVKDPMVI  64

Query:  82 GHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGS 141
           GHE++G V  +G  V  L+ GDRVA+EPGVPC +CQ C+EG+YNLCP++ F ATPP DG+
Sbjct:  65 GHEASGTVVKVGKNVKHLKKGDRVAVEPGVPCRRCQFCKEGKYNLCPDLTFCATPPDDGN 124

Query: 142 LARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLN 201
           LARY  H A +C++LP++VSLEEGA+ EPLSV VHA RRAG  +G+ VLV+GAGPIGL++
Sbjct: 125 LARYYVHAADFCHKLPDNVSLEEGALLEPLSVGVHACRRAGVQLGTTVLVIGAGPIGLVS 184

Query: 202 CMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALV--VQQALDGAQA 259
            + AKA+GA  +V T    RRL  A+ + GAD  +      E +++++  ++ A+ G   
Sbjct: 185 VLAAKAYGA-FVVCTARSPRRLEVAK-NCGADVTLVVDPAKEEESSIIERIRSAI-GDLP 241

Query: 260 DIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTY 319
           ++ +DC+G E  + + +++ R GG + LVGMGS  + VPLV+A +REIDI  VFRY N Y
Sbjct: 242 NVTIDCSGNEKCITIGINITRTGGTLMLVGMGSQMVTVPLVNACAREIDIKSVFRYCNDY 301

Query: 320 PTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLT 369
           P  + ++ASGR NVK L+TH F  LE++    AFE AR  A+  +KVM++
Sbjct: 302 PIALEMVASGRCNVKQLVTHSFK-LEQTV--DAFEAARKKADNTIKVMIS 348

gb|AAL37293.1| sorbitol dehydrogenase [Malus x domestica]
(371 aa)

Score: 332 bits (852), Expect: 9.15408e-90
Length: 356, Idn/Pos/Gap = 168/237/13 (47%/66%/3%)

Query:  19 EKANPCGVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDP  78
           ++ N    L+  + L++    +P   P +VR++++ VGICGSDVH++ +  C  F + +P
Sbjct:  25 QQENMAAWLLGVKNLKIQPYKLPNLGPHDVRVRLKAVGICGSDVHHFKNMRCVDFIVKEP  84

Query:  79 MIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPV 138
           M+IGHE AG++E +G+ V  L  GDRVALEPG+ C +C  C++GRYNLC  +KFF +PP 
Sbjct:  85 MVIGHECAGIIEEVGSEVEDLVPGDRVALEPGISCKRCNLCKQGRYNLCRKMKFFGSPPN 144

Query: 139 DGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIG 198
           +G LA  V HP   C++LP++VSLEEGAMCEPLSV +HA RRA     + VLV+GAGPIG
Sbjct: 145 NGCLANQVVHPGDLCFKLPDNVSLEEGAMCEPLSVGIHACRRANVCQETNVLVVGAGPIG 204

Query: 199 LLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVI----NTRDLDEHDAALVVQQAL 254
           L+  + A+AFGA  IV+ D++  RL  A++  GADAV+    N  D+ E  A   +Q+ L
Sbjct: 205 LVTLLAARAFGAPRIVIADVNHERLLIAKS-LGADAVVKVSTNIEDVAEEVAK--IQKVL 261

Query: 255 DGAQADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFR 314
           +    D+  DCAG   T+  A+   RPGG++CLVGMG   M +PL   ++REID+ G+FR
Sbjct: 262 ENG-VDVTFDCAGFNKTITTALSATRPGGKVCLVGMGQREMTLPL---ATREIDVIGIFR 317

Query: 315 YSNTYPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLTI 370
           Y NT+P C+  L SG+++VKPLITHRF G  +  +E AFET+    N A+KVM  +
Sbjct: 318 YQNTWPLCLEFLRSGKIDVKPLITHRF-GFSQKEVEEAFETSARGGN-AIKVMFNL 371

ref|XP_413719.1| PREDICTED: similar to Sorbitol dehydrogenase (L-iditol 2-dehydrogenase) [Gallus gallus]
(355 aa)

Score: 332 bits (851), Expect: 1.166e-89
Length: 344, Idn/Pos/Gap = 171/233/9 (49%/67%/2%)

Query:  26 VLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHES  85
           V+ R  +LR+  R +P P P EV L+M  VGICGSDVHYW HG  G F + DPM++GHE+
Sbjct:  11 VVHRAGDLRLENRPIPEPGPNEVLLRMHSVGICGSDVHYWQHGRIGDFVVKDPMVLGHEA  70

Query:  86 AGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARY 145
           +G V  +GAGVT L+ GDRVA+EPGVP    + C+ GRYNL P I F ATPP DG+L RY
Sbjct:  71 SGTVIKVGAGVTHLKPGDRVAIEPGVPRETDEFCKTGRYNLSPTIFFCATPPDDGNLCRY 130

Query: 146 VCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVA 205
             H A++CY+LP+SV+ EEGA+ EPLSV +HA +RAG T+GS V V G+GPIGL+N ++A
Sbjct: 131 YKHSASYCYKLPDSVTFEEGALIEPLSVGIHACKRAGVTLGSRVFVSGSGPIGLVNVIIA 190

Query: 206 KAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDC 265
           K  GA+ +VVTD+   RL  A+   GAD  I  ++    + A  V+  L G   +I ++C
Sbjct: 191 KMMGAAAVVVTDLSASRLQTAK-ELGADFTIQIKNETPQEVAAKVESLL-GCMPEITVEC 248

Query: 266 AGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIAL 325
            G+++ ++ +++  R GG + LVG+G   + VP+V+A+ RE+DI G+FRY NT+P  I+L
Sbjct: 249 TGVQACIQASIYATRSGGTLVLVGLGPEMVTVPIVNAAVREVDIRGIFRYCNTWPVAISL 308

Query: 326 LASGRVNVKPLITHRFMGLEESSLEAAFETARTAANG-AVKVML 368
           LAS R+N+KPL+THRF       LE A E   T   G  VK+ML
Sbjct: 309 LASKRINIKPLVTHRF------PLEKALEAFETTKRGEGVKIML 346

gb|AAK93491.1| LP12301p [Drosophila melanogaster]
(360 aa)

Score: 331 bits (849), Expect: 2.00557e-89
Length: 351, Idn/Pos/Gap = 179/242/4 (50%/68%/1%)

Query:  20 KANPCGVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPM  79
           K N   VL    ++R+  R +P  A  EV L M  VGICGSDVHY  HG  G F L  PM
Sbjct:   3 KDNLTAVLHGIEDMRLEQRPIPEIADDEVLLAMDSVGICGSDVHYLAHGRIGDFVLTKPM  62

Query:  80 IIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVD 139
           IIGHESAGVV  LG  VT+ +VGDRVA+EPGVPC +C  C++G+YNLCP + F ATPP D
Sbjct:  63 IIGHESAGVVAKLGKKVTTPKVGDRVAIEPGVPCRKCDHCKQGKYNLCPGMVFCATPPYD 122

Query: 140 GSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGL 199
           G+L RY  H A +C++LP+ V++EEGA+ EPLSV VHA +RA  T+GS VL+LGAGPIGL
Sbjct: 123 GNLTRYYKHAADFCFKLPDHVTMEEGALLEPLSVGVHACKRAEVTLGSKVLILGAGPIGL 182

Query: 200 LNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQA 259
           +  M A+A GAS I++TD+  +RL  A+       ++  RD    + A++VQ+ + G Q 
Sbjct: 183 VTLMAAQAMGASEILITDLVQQRLDVAKELGATHTLLLKRDQTAEETAVLVQKTM-GGQP 241

Query: 260 DIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTY 319
           D ++DC G ES+ RLA+   R GG + +VGMG++ + +PL++A +RE+DI GVFRY N Y
Sbjct: 242 DKSIDCCGAESSARLAIFATRSGGIVVVVGMGAAEIKLPLINALAREVDIRGVFRYCNDY 301

Query: 320 PTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLTI 370
              +AL+ASG+VNVK L+TH F  ++E++   AFET+R    GA+KVM+ +
Sbjct: 302 AAALALVASGKVNVKRLVTHHF-DIKETA--KAFETSRKGLGGAIKVMIHV 349

emb|CAA94841.1| Hypothetical protein R04B5.5 [Caenorhabditis elegans]
ref|NP_505591.1| sorbitol dehydrogenase (5K569) [Caenorhabditis elegans]
pir||T23889 hypothetical protein R04B5.5 - Caenorhabditis elegans
(347 aa)

Score: 328 bits (842), Expect: 1.12806e-88
Length: 349, Idn/Pos/Gap = 162/239/10 (46%/68%/2%)

Query:  22 NPCGVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMII  81
           N   VL    +LR+    +P P P +V +++  VGICGSDVHYW HG+ GPF + +PMI+
Sbjct:   5 NLSAVLYGVDDLRLEQVPIPKPGPNQVLVKVHTVGICGSDVHYWTHGAIGPFVVKEPMIV  64

Query:  82 GHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGS 141
           GHE++G+V  +G  V  L+VGDR+A+EPG+PC  C+ C+ GRYNLCP ++FFATPPV G+
Sbjct:  65 GHETSGIVSEVGNEVKHLKVGDRIAMEPGLPCKLCEHCKTGRYNLCPEMRFFATPPVHGT 124

Query: 142 LARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLN 201
           L+R+V H A +C++LP+++S E+GA+ EPLSVA+HA RR    +G  VLVLGAGPIG+LN
Sbjct: 125 LSRFVVHDADFCFKLPDNLSFEDGALIEPLSVAIHACRRGNVQMGHRVLVLGAGPIGVLN 184

Query: 202 CMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINT--RDLDEHDAALVVQQALDGAQA 259
            + AKA GA  +V+TD+DD RLA A+   GADA IN   + LD   + ++   AL   Q 
Sbjct: 185 LITAKAVGAGKVVITDLDDGRLALAKK-LGADATINVKGKSLDAVKSEIIT--ALGDQQP 241

Query: 260 DIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTY 319
           D+ ++C G + ++  A+   + GG I LVG+G+  + +P++++++RE+D+ G+FRY N Y
Sbjct: 242 DVCIECTGAQPSIETAITTTKSGGVIVLVGLGADRVEIPIIESATREVDMRGIFRYVNCY 301

Query: 320 PTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVML 368
           PT I L++SG++N+  L T     LEE+  + AF+  RT     +KV +
Sbjct: 302 PTAIELISSGKLNLSGL-TRAHYKLEET--QEAFK--RTQKADVIKVFI 345

ref|NP_524311.1| CG4649-PA [Drosophila melanogaster]
gb|AAF54573.1| CG4649-PA [Drosophila melanogaster]
gb|AAL13960.1| LD47736p [Drosophila melanogaster]
gb|AAD00903.1| sorbitol dehydrogenase [Drosophila melanogaster]
(360 aa)

Score: 327 bits (838), Expect: 3.33738e-88
Length: 349, Idn/Pos/Gap = 178/232/4 (51%/66%/1%)

Query:  22 NPCGVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMII  81
           N   VL    +LR+  R +P  A  EV L M  VGICGSDVHY  HG  G F L  PMII
Sbjct:   5 NLTAVLHGIEDLRLEQRPIPEIADDEVLLAMDSVGICGSDVHYLAHGRIGDFVLTKPMII  64

Query:  82 GHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGS 141
           GHE+AGVV  LG  VT+L+VGDRVA+EPGVPC  C  C++GRYNLC ++ F ATPP DG+
Sbjct:  65 GHEAAGVVAKLGKKVTTLKVGDRVAIEPGVPCRYCDHCKQGRYNLCADMVFCATPPYDGN 124

Query: 142 LARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLN 201
           L RY  H A +C++LP+ VS+EEGA+ EPLSV VHA RRAG  +GS VL+LGAGPIGL+ 
Sbjct: 125 LTRYYKHAADFCFKLPDHVSMEEGALLEPLSVGVHACRRAGVGLGSKVLILGAGPIGLVT 184

Query: 202 CMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADI 261
            + A+A GAS I++TD+  +RL  A+       ++  RD    +   VV Q +     D 
Sbjct: 185 LLAAQAMGASEILITDLVQQRLDVAKELGATHTLLLQRDQSAEETVKVVHQTMSEV-PDK 243

Query: 262 ALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPT 321
           ++DC G ES+ RLA+   R GG + +VGMG+  + +PL++A +REIDI GVFRY N Y  
Sbjct: 244 SIDCCGAESSARLAIFATRSGGVVVVVGMGAPEVKLPLINALAREIDIRGVFRYCNDYSA 303

Query: 322 CIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLTI 370
            +AL+ASG+VNVK L+TH +   E +    AFET+R    GA+KVM+ +
Sbjct: 304 ALALVASGKVNVKRLVTHHYDITETAE---AFETSRRGTGGAIKVMIHV 349

emb|CAE64010.1| Hypothetical protein CBG08605 [Caenorhabditis briggsae]
(347 aa)

Score: 322 bits (826), Expect: 9.08592e-87
Length: 334, Idn/Pos/Gap = 157/231/8 (47%/69%/2%)

Query:  37 LRSVPAPAPG--EVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGA  94
           L  VP P PG  +V +++  VGICGSDVHYW HG+ GPF + +PMI+GHE++GVV  +G+
Sbjct:  18 LEQVPIPKPGSKQVLVRVHTVGICGSDVHYWTHGAIGPFVVKEPMIVGHETSGVVSEIGS  77

Query:  95 GVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCY 154
            V  L+VGDR+A+EPG+PC  C+ C+ GRYNLCP ++FFATPP++G+L+RYV H A +C+
Sbjct:  78 EVQHLKVGDRIAMEPGLPCKLCEHCKTGRYNLCPEMRFFATPPINGTLSRYVVHDADFCF 137

Query: 155 RLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIV 214
           +LP+++S E+GA+ EPLSVA+H+ RR    +G  VLVLGAGPIG+LN + AK+ GA  +V
Sbjct: 138 KLPDNLSFEDGALLEPLSVAIHSCRRGNVQMGHRVLVLGAGPIGVLNLLTAKSVGAGKVV 197

Query: 215 VTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRL 274
           +TD+DD RL+ A+   GADA IN +          +  AL G Q  + ++C G + ++  
Sbjct: 198 ITDLDDGRLSLAKK-LGADATINVKGKSLEAVRAEIISALGGQQPHVCVECTGAQPSIET 256

Query: 275 AMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASGRVNVK 334
           A+   + GG I LVG+G+  + +P++++++RE+DI G+FRY N YPT I LL+SG++++ 
Sbjct: 257 AITTTKSGGVIVLVGLGADRVEIPIIESATREVDIRGIFRYVNCYPTAIELLSSGKLDLS 316

Query: 335 PLITHRFMGLEESSLEAAFETARTAANGAVKVML 368
            L    +  LEE +LEA     RT     +KV +
Sbjct: 317 GLSRAHYK-LEE-TLEA---FKRTQKADVIKVFI 345

ref|XP_392401.1| similar to CG4649-PA [Apis mellifera]
(349 aa)

Score: 319 bits (817), Expect: 8.71719e-86
Length: 350, Idn/Pos/Gap = 173/232/7 (49%/66%/2%)

Query:  20 KANPCGVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPM  79
           K N   +L    ++R+    +  P   EV +QM CVGICGSDVHY  +G  G F + +PM
Sbjct:   3 KDNLTAILYGINDIRLEQTPIEEPNQDEVLIQMGCVGICGSDVHYLVNGRIGDFVVREPM  62

Query:  80 IIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVD 139
           I+GHES+GVV  LG  V +L+VGDRVA+EPGV C  C+ C+EGRYNLC  + F ATPPV 
Sbjct:  63 IMGHESSGVVVKLGKDVKNLKVGDRVAIEPGVSCRYCKFCKEGRYNLCKEMVFCATPPVH 122

Query: 140 GSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGL 199
           GSL R+  H A +C++LP+ VSL EGA+ EPLSV VHA +RA   IGS VL+LGAGPIGL
Sbjct: 123 GSLRRFYKHAADFCFKLPDHVSLAEGALLEPLSVGVHACKRANIGIGSKVLILGAGPIGL 182

Query: 200 LNCMVAKAFGASIIVVTDIDDRRLAFA-ETHAGADAVINTRDLDEHDAALVVQQALDGAQ 258
           ++ +VAKA GAS IV+TD+   RL  A +  A    +I   D++E     +++  L G +
Sbjct: 183 VSLLVAKAMGASKIVITDLMQSRLDLAKQLGANETLLIKKDDVEEKTVQKIIE--LFGEE 240

Query: 259 ADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNT 318
            D  +D  G ES++RLA+   + GG   LVGMG   + VPL++A  RE+DI GVFRY+N 
Sbjct: 241 PDKTIDACGAESSIRLAIFATKSGGVAVLVGMGPPEVRVPLINALIREVDIRGVFRYAND 300

Query: 319 YPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVML 368
           Y   + LLAS +++VKPLITH +  LE++    AFET+++  N  VKVM+
Sbjct: 301 YADALDLLASRKIDVKPLITHNYK-LEDTV--QAFETSKSGQN-VVKVMI 346

gb|AAX46613.1| sorbitol dehydrogenase [Bos taurus]
(356 aa)

Score: 317 bits (812), Expect: 3.84933e-85
Length: 340, Idn/Pos/Gap = 165/228/9 (48%/67%/2%)

Query:  30 PRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVV  89
           P +LR+    +P P P EV L+M  VGICGSDVHYW HG  G F +  PM++GHE++G V
Sbjct:  16 PGDLRLENYPIPEPGPNEVLLKMHSVGICGSDVHYWQHGRIGDFVVKKPMVLGHEASGTV  75

Query:  90 EALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHP 149
             +G+ V  LQ GDRVA+EPG P    + C+ GRYNL P I F ATPP DG+L R+  H 
Sbjct:  76 VKVGSLVRHLQPGDRVAIEPGAPRETDEFCKIGRYNLSPTIFFCATPPDDGNLCRFYKHN 135

Query: 150 AAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFG 209
           A +CY+LP++V+ EEGA+ EPLSV +HA RRAG T+G+ VLV GAGPIGL++ + AKA G
Sbjct: 136 ANFCYKLPDNVTFEEGALIEPLSVGIHACRRAGVTLGNKVLVCGAGPIGLVSLLAAKAMG 195

Query: 210 ASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLE 269
           A+ +VVTD+   RL+ A+   GAD ++   +    + A  V+  L G++ ++ ++C G+E
Sbjct: 196 AAQVVVTDLSASRLSKAK-EVGADFILQISNESPQEIAKKVEGLL-GSKPEVTIECTGVE 253

Query: 270 STMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASG 329
           ++++  ++    GG + LVG+GS    VPLV A++RE+DI GVFRY NT+P  I++LAS 
Sbjct: 254 TSIQAGIYATHSGGTLVLVGLGSEMTSVPLVHAATREVDIKGVFRYCNTWPMAISMLASK 313

Query: 330 RVNVKPLITHRFMGLEESSLEAAFETARTAANG-AVKVML 368
            VNVKPL+THRF       LE A E   T+  G  +KVM+
Sbjct: 314 SVNVKPLVTHRF------PLEKALEAFETSKKGLGLKVMI 347

gb|AAH75202.1| Sord-prov protein [Xenopus laevis]
(360 aa)

Score: 317 bits (812), Expect: 3.88158e-85
Length: 338, Idn/Pos/Gap = 168/225/9 (49%/66%/2%)

Query:  32 ELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEA  91
           +LR+  R VP P P EV L+M  VGICGSDVHYW HG  G F +  PM++GHE++G V  
Sbjct:  22 DLRLENRPVPEPGPNEVLLKMHSVGICGSDVHYWQHGRIGDFIVKKPMVLGHEASGTVVK  81

Query:  92 LGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAA 151
           +GA V+ L+ GDRVA+EPGVP    + C+ GRYNL P I F ATPP DG+L RY  H A 
Sbjct:  82 VGASVSHLKPGDRVAIEPGVPRETDEFCKMGRYNLSPTIFFCATPPDDGNLCRYYTHNAN 141

Query: 152 WCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGAS 211
           +CY+LP++V+ EEGA+ EPLSV +HA RRAG T+GS V + GAGPIGL++ +VAK  GAS
Sbjct: 142 FCYKLPDNVTFEEGALIEPLSVGIHACRRAGVTLGSRVFICGAGPIGLVSLLVAKMMGAS 201

Query: 212 IIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLEST 271
            +V++D+   RL  A+   GAD V+          A  V++ L G   +I ++C G ES 
Sbjct: 202 QVVISDLSLSRLEKAK-ELGADFVVQVATEPPEVIARKVEELL-GTMPEITIECTGAESC 259

Query: 272 MRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASGRV 331
           ++  ++  R GG + LVG+G + ++VP+V+A+ RE+DI G+FRY NT+P  I++L+S RV
Sbjct: 260 IQAGIYATRSGGTLILVGLGPAMVNVPIVNAAVREVDIRGIFRYCNTWPMAISMLSSKRV 319

Query: 332 NVKPLITHRFMGLEESSLEAAFETARTAANG-AVKVML 368
           NV PL+THRF       LE A E   T   G  VKVML
Sbjct: 320 NVAPLVTHRF------PLEKAVEAFETTKKGVGVKVML 351

ref|NP_001011264.1| hypothetical protein LOC496715 [Xenopus tropicalis]
gb|AAH87971.1| Hypothetical LOC496715 [Xenopus tropicalis]
(360 aa)

Score: 316 bits (810), Expect: 6.7888e-85
Length: 338, Idn/Pos/Gap = 168/225/9 (49%/66%/2%)

Query:  32 ELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEA  91
           +LR+  R VP P P EV L+M  VGICGSDVHYW HG  G F +  PM++GHE++G V  
Sbjct:  22 DLRLENRPVPEPGPNEVLLKMHSVGICGSDVHYWQHGRIGDFIVKKPMVLGHEASGTVVK  81

Query:  92 LGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAA 151
           +GA V+ L+ GDRVA+EPGVP    + C+ GRYNL P I F ATPP DG+L RY  H A 
Sbjct:  82 VGASVSHLKPGDRVAIEPGVPRETDEFCKMGRYNLSPTIFFCATPPDDGNLCRYYTHNAN 141

Query: 152 WCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGAS 211
           +CY+LP++V+ EEGA+ EPLSV +HA RRAG T+GS V + GAGPIGL++ +VAK  GAS
Sbjct: 142 FCYKLPDNVTFEEGALIEPLSVGIHACRRAGVTLGSRVFICGAGPIGLVSLLVAKMMGAS 201

Query: 212 IIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLEST 271
            +V++D+   RL  A+   GAD V+          A  V++ L G   +I ++C G ES 
Sbjct: 202 QVVISDLSLPRLEKAK-ELGADFVVQVTTEAPEVIAQKVEKLL-GIMPEITIECTGAESC 259

Query: 272 MRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASGRV 331
           ++  ++  R GG + LVG+G + ++VP+V+A+ RE+DI G+FRY NT+P  I++L+S RV
Sbjct: 260 IQAGIYATRSGGTLILVGLGPAMVNVPIVNAAVREVDIRGIFRYCNTWPMAISMLSSKRV 319

Query: 332 NVKPLITHRFMGLEESSLEAAFETARTAANG-AVKVML 368
           NV PL+THRF       LE A E   T   G  VKVML
Sbjct: 320 NVAPLVTHRF------PLENAAEAFETTKKGMGVKVML 351

prf||2121217A sorbitol dehydrogenase
(357 aa)

Score: 316 bits (809), Expect: 7.75838e-85
Length: 340, Idn/Pos/Gap = 165/226/9 (48%/66%/2%)

Query:  30 PRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVV  89
           P +LR+    +P P P EV L+M  VGICGSDVHYW +G  G F +  PM++GHE++G V
Sbjct:  17 PGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGDFIVKKPMVLGHEASGTV  76

Query:  90 EALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHP 149
           E +G+ V  L+ GDRVA+EPG P    + C+ GRYNL P+I F ATPP DG+L R+  H 
Sbjct:  77 EKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRFYKHN 136

Query: 150 AAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFG 209
           AA+CY+LP++V+ EEGA+ EPLSV +HA RR G T+G  VLV GAGPIG++  +VAKA G
Sbjct: 137 AAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMG 196

Query: 210 ASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLE 269
           A+ +VVTD+   RL+ A+   GAD V+        + A +V+  L G + ++ ++C G E
Sbjct: 197 AAQVVVTDLSATRLSKAK-EIGADLVLQISKESPQEIARLVEGQL-GCKPEVTIECTGAE 254

Query: 270 STMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASG 329
           ++++  ++  R GG + LVG+GS    VPL+ A+ RE+DI GVFRY NT+P  I++LAS 
Sbjct: 255 ASIQAGIYATRSGGTLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYCNTWPVAISMLASK 314

Query: 330 RVNVKPLITHRFMGLEESSLEAAFETARTAANG-AVKVML 368
            VNVKPL+THRF       LE A E   T   G  +K+ML
Sbjct: 315 SVNVKPLVTHRF------PLEKALEAFETFKKGLGLKIML 348

gb|AAH25295.1| Sorbitol dehydrogenase [Homo sapiens]
gb|AAH21085.1| Sorbitol dehydrogenase [Homo sapiens]
gb|AAB61898.1| sorbitol dehydrogenase [Homo sapiens]
gb|AAA66064.1| sorbitol dehydrogenase
ref|NP_003095.1| sorbitol dehydrogenase [Homo sapiens]
(357 aa)

Score: 315 bits (806), Expect: 1.78705e-84
Length: 340, Idn/Pos/Gap = 165/225/9 (48%/66%/2%)

Query:  30 PRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVV  89
           P +LR+    +P P P EV L+M  VGICGSDVHYW +G  G F +  PM++GHE++G V
Sbjct:  17 PGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTV  76

Query:  90 EALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHP 149
           E +G+ V  L+ GDRVA+EPG P    + C+ GRYNL P+I F ATPP DG+L R+  H 
Sbjct:  77 EKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRFYKHN 136

Query: 150 AAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFG 209
           AA+CY+LP++V+ EEGA+ EPLSV +HA RR G T+G  VLV GAGPIG++  +VAKA G
Sbjct: 137 AAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMG 196

Query: 210 ASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLE 269
           A+ +VVTD+   RL+ A+   GAD V+        + A  V+  L G + ++ ++C G E
Sbjct: 197 AAQVVVTDLSATRLSKAK-EIGADLVLQISKESPQEIARKVEGQL-GCKPEVTIECTGAE 254

Query: 270 STMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASG 329
           ++++  ++  R GG + LVG+GS    VPL+ A+ RE+DI GVFRY NT+P  I++LAS 
Sbjct: 255 ASIQAGIYATRSGGTLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYCNTWPVAISMLASK 314

Query: 330 RVNVKPLITHRFMGLEESSLEAAFETARTAANG-AVKVML 368
            VNVKPL+THRF       LE A E   T   G  +K+ML
Sbjct: 315 SVNVKPLVTHRF------PLEKALEAFETFKKGLGLKIML 348

pdb|1PL8|D Chain D, Human SdhNAD+ COMPLEX
pdb|1PL8|C Chain C, Human SdhNAD+ COMPLEX
pdb|1PL8|B Chain B, Human SdhNAD+ COMPLEX
pdb|1PL8|A Chain A, Human SdhNAD+ COMPLEX
pdb|1PL7|D Chain D, Human Sorbitol Dehydrogenase (Apo)
pdb|1PL7|C Chain C, Human Sorbitol Dehydrogenase (Apo)
pdb|1PL7|B Chain B, Human Sorbitol Dehydrogenase (Apo)
pdb|1PL7|A Chain A, Human Sorbitol Dehydrogenase (Apo)
(356 aa)

Score: 315 bits (806), Expect: 1.84769e-84
Length: 340, Idn/Pos/Gap = 165/225/9 (48%/66%/2%)

Query:  30 PRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVV  89
           P +LR+    +P P P EV L+M  VGICGSDVHYW +G  G F +  PM++GHE++G V
Sbjct:  16 PGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTV  75

Query:  90 EALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHP 149
           E +G+ V  L+ GDRVA+EPG P    + C+ GRYNL P+I F ATPP DG+L R+  H 
Sbjct:  76 EKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRFYKHN 135

Query: 150 AAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFG 209
           AA+CY+LP++V+ EEGA+ EPLSV +HA RR G T+G  VLV GAGPIG++  +VAKA G
Sbjct: 136 AAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMG 195

Query: 210 ASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLE 269
           A+ +VVTD+   RL+ A+   GAD V+        + A  V+  L G + ++ ++C G E
Sbjct: 196 AAQVVVTDLSATRLSKAK-EIGADLVLQISKESPQEIARKVEGQL-GCKPEVTIECTGAE 253

Query: 270 STMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASG 329
           ++++  ++  R GG + LVG+GS    VPL+ A+ RE+DI GVFRY NT+P  I++LAS 
Sbjct: 254 ASIQAGIYATRSGGTLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYCNTWPVAISMLASK 313

Query: 330 RVNVKPLITHRFMGLEESSLEAAFETARTAANG-AVKVML 368
            VNVKPL+THRF       LE A E   T   G  +K+ML
Sbjct: 314 SVNVKPLVTHRF------PLEKALEAFETFKKGLGLKIML 347

gb|EAA08770.2| ENSANGP00000011358 [Anopheles gambiae str. PEST]
ref|XP_313338.2| ENSANGP00000011358 [Anopheles gambiae str. PEST]
(357 aa)

Score: 315 bits (806), Expect: 1.99179e-84
Length: 349, Idn/Pos/Gap = 170/230/4 (48%/65%/1%)

Query:  22 NPCGVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMII  81
           N   VL    +LR+  R +P P   EV L+M  VGICGSDVHY   G  G F +  PM+I
Sbjct:   4 NLTAVLYGIEDLRLEQRPIPVPKDDEVLLEMDVVGICGSDVHYLVKGRIGDFIVKKPMVI  63

Query:  82 GHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGS 141
           GHE++GVV  +G+ V  LQVGDRVA+EPG  C  C+ C+ G YNLC  + F ATPP DG+
Sbjct:  64 GHEASGVVSKVGSKVKHLQVGDRVAIEPGYGCRTCEYCKGGSYNLCAEMIFCATPPYDGN 123

Query: 142 LARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLN 201
           L RY  HPA +CY+LP+ V++EEGA+ EPLSV VHA RRA   +GS VL+LGAGPIGL+ 
Sbjct: 124 LTRYFAHPADFCYKLPDHVTMEEGALLEPLSVGVHACRRANVGLGSQVLILGAGPIGLVT 183

Query: 202 CMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADI 261
            +VAKA GA  ++VTD+   RL  A+     + +   +D  E +   ++ + + GA  D 
Sbjct: 184 LIVAKAMGAGKVLVTDLLQNRLDVAKELGADETLAIPKDATEAELVTIIHERMGGA-PDK 242

Query: 262 ALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPT 321
            +DC+G EST RL +   + GG   +VGMG+  + +PLV+A +RE+DI GVFRY N YP 
Sbjct: 243 TIDCSGAESTARLMILATKSGGVGVMVGMGAPEVKLPLVNALAREVDIRGVFRYCNDYPV 302

Query: 322 CIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLTI 370
            ++L+ASG+VNVK LITH F  +E+++   AF T R   +GA+KVM+ +
Sbjct: 303 ALSLVASGKVNVKRLITHHF-NIEDTA--KAFHTTRHGVDGAIKVMIHV 348

sp|Q00796|DHSO_HUMAN Sorbitol dehydrogenase (L-iditol 2-dehydrogenase)
gb|AAA80566.1| L-iditol-2 dehydrogenase
gb|AAA80565.1| L-iditol-2 dehydrogenase
(357 aa)

Score: 314 bits (805), Expect: 2.11159e-84
Length: 340, Idn/Pos/Gap = 165/225/9 (48%/66%/2%)

Query:  30 PRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVV  89
           P +LR+    +P P P EV L+M  VGICGSDVHYW +G  G F +  PM++GHE++G V
Sbjct:  17 PGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTV  76

Query:  90 EALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHP 149
           E +G+ V  L+ GDRVA+EPG P    + C+ GRYNL P+I F ATPP DG+L R+  H 
Sbjct:  77 EKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRFYKHN 136

Query: 150 AAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFG 209
           AA+CY+LP++V+ EEGA+ EPLSV +HA RR G T+G  VLV GAGPIG++  +VAKA G
Sbjct: 137 AAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMG 196

Query: 210 ASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLE 269
           A+ +VVTD+   RL+ A+   GAD V+        + A  V+  L G + ++ ++C G E
Sbjct: 197 AAQVVVTDLSATRLSKAK-EIGADLVLQISKESPQEIARKVEGLL-GCKPEVTIECTGAE 254

Query: 270 STMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASG 329
           ++++  ++  R GG + LVG+GS    VPL+ A+ RE+DI GVFRY NT+P  I++LAS 
Sbjct: 255 ASIQAGIYATRSGGTLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYCNTWPVAISMLASK 314

Query: 330 RVNVKPLITHRFMGLEESSLEAAFETARTAANG-AVKVML 368
            VNVKPL+THRF       LE A E   T   G  +K+ML
Sbjct: 315 SVNVKPLVTHRF------PLEKALEAFETFKKGLGLKIML 348

emb|CAE64012.1| Hypothetical protein CBG08607 [Caenorhabditis briggsae]
(347 aa)

Score: 314 bits (804), Expect: 2.80422e-84
Length: 330, Idn/Pos/Gap = 150/224/3 (45%/67%/0%)

Query:  22 NPCGVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMII  81
           N   VL    +LR+    +P P P +V +++  VGICGSDVH+W  G+ GPF + +PMI+
Sbjct:   5 NLSAVLHGVDDLRLEQVPIPKPGPKQVLVRVHTVGICGSDVHFWTRGAIGPFIVKEPMIV  64

Query:  82 GHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGS 141
           GHE++GVV  +G+ V  L+VGDR+A+EPG+ C  C+ C+ GRYNLCP  +FFATPP++G+
Sbjct:  65 GHETSGVVSEIGSEVQHLKVGDRIAMEPGLSCKLCEHCKTGRYNLCPESRFFATPPINGA 124

Query: 142 LARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLN 201
           L+RYV H   +C++LP+++S E+GA+ EPLSVA+HA RR    +G  VLVLGAGPIG+LN
Sbjct: 125 LSRYVVHDDDFCFKLPDNLSFEDGALIEPLSVAIHACRRGNVRMGHRVLVLGAGPIGVLN 184

Query: 202 CMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADI 261
            + AK+ GA  +V+TD+DD RL+ A+   GADA IN +          +  AL G Q  +
Sbjct: 185 LLTAKSVGAGKVVITDLDDGRLSLAKK-LGADATINVKGKSLEAVRAEIISALGGQQPHV 243

Query: 262 ALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPT 321
            ++C G + ++  A+   + GG I LVG+G+  + +P++++++RE+DI G FRY+N YPT
Sbjct: 244 CVECTGAQPSIETAITTTKSGGVIVLVGLGADRVEIPIIESATREVDIRGTFRYANCYPT 303

Query: 322 CIALLASGRVNVKPLITHRFMGLEESSLEA 351
            I LL+SG++++  L    +    E +LEA
Sbjct: 304 AIELLSSGKLDLSGLTRAHYK--LEDTLEA 331

pir||S10065 L-iditol 2-dehydrogenase (EC 1.1.1.14) - sheep (tentative sequence)
(354 aa)

Score: 313 bits (801), Expect: 6.19525e-84
Length: 340, Idn/Pos/Gap = 164/227/10 (48%/66%/2%)

Query:  30 PRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVV  89
           P +LR+    +P P P EV L+M  VGICGSDVHYW  G  G F +  PM++GHE++G V
Sbjct:  15 PGDLRLENYPIPEPGPNEVLLKMHSVGICGSDVHYW-QGRIGBFVVKKPMVLGHEASGTV  73

Query:  90 EALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHP 149
             +G+ V  LQ GDRVA++PG P    + C+ GRYNL P I F ATPP DG+L R+  H 
Sbjct:  74 VKVGSLVRHLQPGDRVAIQPGAPRQTDEFCKIGRYNLSPTIFFCATPPDDGNLCRFYKHN 133

Query: 150 AAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFG 209
           A +CY+LP++V+ EEGA+ EPLSV +HA RRAG T+G+ VLV GAGPIGL+N + AKA G
Sbjct: 134 ANFCYKLPDNVTFEEGALIEPLSVGIHACRRAGVTLGNKVLVCGAGPIGLVNLLAAKAMG 193

Query: 210 ASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLE 269
           A+ +VVTD+   RL+ A+   GAD ++   +    + A  V+  L G++ ++ ++C G+E
Sbjct: 194 AAQVVVTDLSASRLSKAK-EVGADFILEISNESPEEIAKKVEGLL-GSKPEVTIECTGVE 251

Query: 270 STMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASG 329
           ++++  ++    GG + LVG+GS    VPLV A++RE+DI GVFRY NT+P  I++LAS 
Sbjct: 252 TSIQAGIYATHSGGTLVLVGLGSEMTSVPLVHAATREVDIKGVFRYCNTWPMAISMLASK 311

Query: 330 RVNVKPLITHRFMGLEESSLEAAFETARTAANG-AVKVML 368
            VNVKPL+THRF       LE A E   T+  G  +KVM+
Sbjct: 312 SVNVKPLVTHRF------PLEKALEAFETSKKGLGLKVMI 345

emb|CAF99680.1| unnamed protein product [Tetraodon nigroviridis]
(367 aa)

Score: 311 bits (797), Expect: 2.1122e-83
Length: 361, Idn/Pos/Gap = 173/241/21 (47%/66%/5%)

Query:  22 NPCGVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMII  81
           N   VL  P +LR++   VP P P +V LQM  VGICGSDVHYW HG    F + DPM++
Sbjct:   5 NLSAVLYSPGDLRLVHLPVPEPGPNDVLLQMHSVGICGSDVHYWQHGRIADFVVKDPMVL  64

Query:  82 GHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGS 141
           GHE++G V  +G  V  L+VGDRVA+EPGVP    +  + G+YNL P I   ATPP DG+
Sbjct:  65 GHEASGRVVKVGPAVKHLKVGDRVAIEPGVPREMDEYFKTGKYNLSPTIFLCATPPDDGN 124

Query: 142 LARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLN 201
           L RY  H A +CY+LP++V+ EEGA+ EPLSV +HA +RAG T+GS VL+ GAGPIGL+ 
Sbjct: 125 LCRYYKHNANFCYKLPDNVTFEEGALIEPLSVGIHACQRAGVTLGSTVLICGAGPIGLVC 184

Query: 202 CMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVIN-TRDLDEHDAALVVQQALDGAQAD 260
            +VAKA GAS +++TD+   RLA A+   GAD  +  T++++    A  V+ +L G Q  
Sbjct: 185 LIVAKAMGASQVIITDLFPERLALAK-ELGADFQLKVTKEVEPKQLAKNVEDSL-GVQPH 242

Query: 261 IALDCAGLESTMRLAMHV-------------VRPGGRICLVGMGSSAMHVPLVDASSREI 307
           + ++C G+ES+++ A++V              R GG + +VG+G+  + +PL++A++RE+
Sbjct: 243 VTIECTGVESSIQTAIYVREGHSNDYFSFQATRSGGVVVVVGLGNQMVTLPLINAATREV 302

Query: 308 DIFGVFRYSNTYPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVM 367
           DI GVFRY NT+P  IA+LASG+V+VKPL+THRF  LE+  +  AFET R      +KVM
Sbjct: 303 DIRGVFRYRNTWPMAIAMLASGKVDVKPLVTHRF-PLEQ--VVQAFETTRQGI--GIKVM 357

Query: 368 L 368
           L
Sbjct: 358 L 358

sp|P07846|DHSO_SHEEP Sorbitol dehydrogenase (L-iditol 2-dehydrogenase)
(354 aa)

Score: 311 bits (796), Expect: 2.43409e-83
Length: 340, Idn/Pos/Gap = 164/227/10 (48%/66%/2%)

Query:  30 PRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVV  89
           P +LR+    +P P P EV L+M  VGICGSDVHYW  G  G F +  PM++GHE++G V
Sbjct:  15 PGDLRLENYPIPEPGPNEVLLKMHSVGICGSDVHYW-QGRIGDFVVKKPMVLGHEASGTV  73

Query:  90 EALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHP 149
             +G+ V  LQ GDRVA++PG P    + C+ GRYNL P I F ATPP DG+L R+  H 
Sbjct:  74 VKVGSLVRHLQPGDRVAIQPGAPRQTDEFCKIGRYNLSPTIFFCATPPDDGNLCRFYKHN 133

Query: 150 AAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFG 209
           A +CY+LP++V+ EEGA+ EPLSV +HA RRAG T+G+ VLV GAGPIGL+N + AKA G
Sbjct: 134 ANFCYKLPDNVTFEEGALIEPLSVGIHACRRAGVTLGNKVLVCGAGPIGLVNLLAAKAMG 193

Query: 210 ASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLE 269
           A+ +VVTD+   RL+ A+   GAD ++   +    + A  V+  L G++ ++ ++C G+E
Sbjct: 194 AAQVVVTDLSASRLSKAK-EVGADFILEISNESPEEIAKKVEGLL-GSKPEVTIECTGVE 251

Query: 270 STMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASG 329
           ++++  ++    GG + LVG+GS    VPLV A++RE+DI GVFRY NT+P  I++LAS 
Sbjct: 252 TSIQAGIYATHSGGTLVLVGLGSEMTSVPLVHAATREVDIKGVFRYCNTWPMAISMLASK 311

Query: 330 RVNVKPLITHRFMGLEESSLEAAFETARTAANG-AVKVML 368
            VNVKPL+THRF       LE A E   T+  G  +KVM+
Sbjct: 312 SVNVKPLVTHRF------PLEKALEAFETSKKGLGLKVMI 345

emb|CAH89506.1| hypothetical protein [Pongo pygmaeus]
(357 aa)

Score: 310 bits (795), Expect: 2.99866e-83
Length: 340, Idn/Pos/Gap = 165/223/9 (48%/65%/2%)

Query:  30 PRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVV  89
           P +LR+    +P P P EV L+M  VGICGSDVHYW  G  G F +  PM++GHE++G V
Sbjct:  17 PGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEDGRIGNFIVKKPMVLGHEASGTV  76

Query:  90 EALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHP 149
           E +G+ V  L+ GDRVA+EPG P    + C+ GRYNL P+I F ATPP DG+L R+  H 
Sbjct:  77 EKVGSLVKHLKPGDRVAIEPGAPRENDEFCKIGRYNLSPSIFFCATPPDDGNLCRFYKHN 136

Query: 150 AAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFG 209
           AA+CY+LP++V+ EEGAM EPLSV +HA RR G T+G  VLV GAGPIG++  +VAKA G
Sbjct: 137 AAFCYKLPDNVTFEEGAMIEPLSVGIHACRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMG 196

Query: 210 ASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLE 269
           A+ +VVTD+   RL+ A+   GAD V+        + A  V+  L G + ++ ++C G E
Sbjct: 197 AAQVVVTDLSATRLSKAK-EIGADLVLQISKESPQEIARKVEGLL-GCKPEVTIECTGAE 254

Query: 270 STMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASG 329
           ++++  ++    GG + LVG+GS    +PL+ A+ RE+DI GVFRY NT+P  I++LAS 
Sbjct: 255 ASIQAGIYATHSGGTLVLVGLGSEMTTIPLLHAAIREVDIKGVFRYCNTWPVAISMLASK 314

Query: 330 RVNVKPLITHRFMGLEESSLEAAFETARTAANG-AVKVML 368
            VNVKPLITHRF       LE A E   T   G  +K+ML
Sbjct: 315 SVNVKPLITHRF------PLEKALEAFETFKKGLGLKIML 348

gb|AAB69288.1| sorbitol dehydrogenase [Callithrix sp.]
(357 aa)

Score: 310 bits (793), Expect: 5.60662e-83
Length: 344, Idn/Pos/Gap = 165/226/9 (47%/65%/2%)

Query:  26 VLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHES  85
           V++ P +LR+    +P P P EV L++  VGICGSDVHYW HG  G F +  PM++GHE+
Sbjct:  13 VVLGPGDLRLENYPIPEPGPNEVLLRIHSVGICGSDVHYWQHGRIGDFIVKKPMVLGHEA  72

Query:  86 AGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARY 145
           +G V  +G+ V  L+ GDRVA+EPG P    + C+ GRYNL P I F ATPP DG+L R+
Sbjct:  73 SGRVVKVGSLVKHLKPGDRVAIEPGAPRETDEFCKTGRYNLSPTIFFCATPPDDGNLCRF 132

Query: 146 VCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVA 205
             H AA+CY+LP++V+ EEGA+ EPLSV +HA RR G  +G+ VLV GAGPIGL+  +VA
Sbjct: 133 YKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVALGNKVLVCGAGPIGLVTLLVA 192

Query: 206 KAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDC 265
           KA GAS +VVTD+   RL+ A+   GAD  +        + A  V+  L G + ++ ++C
Sbjct: 193 KAMGASQVVVTDLSAPRLSKAK-EIGADFSLQISKESPQEIASKVEGLL-GCKPEVTIEC 250

Query: 266 AGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIAL 325
            G E++++  ++  R GG + LVG+GS    VPLV A++RE+DI GVFRYSNT+P  I++
Sbjct: 251 TGAEASIQAGIYATRSGGTLVLVGLGSEMTTVPLVHATTREVDIKGVFRYSNTWPMAISM 310

Query: 326 LASGRVNVKPLITHRFMGLEESSLEAAFETARTAANG-AVKVML 368
           L S  VN+ PL+THRF       LE A E   T+  G  +KVML
Sbjct: 311 LESKSVNLMPLVTHRF------PLEKALEAFETSKKGLGLKVML 348

emb|CAA52670.1| L-iditol 2-dehydrogenase [Rattus norvegicus]
pir||S16132 L-iditol 2-dehydrogenase (EC 1.1.1.14), long form - rat
(399 aa)

Score: 308 bits (788), Expect: 1.95996e-82
Length: 365, Idn/Pos/Gap = 168/234/10 (46%/64%/2%)

Query:   5 ETELEESDAGSVLNEKANPCGVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHY  64
           +T  +ESD  +    + N   V+  P ++R+    +P   P +V L+M  VGICGSDVHY
Sbjct:  35 DTSKQESDMAAPAKGE-NLSLVVHGPGDIRLENYPIPELGPNDVLLKMHSVGICGSDVHY  93

Query:  65 WWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRY 124
           W HG  G F +  PM++GHE+AG V  +G  V  L+ GDRVA+EPGVP    + C+ GRY
Sbjct:  94 WEHGRIGDFVVKKPMVLGHEAAGTVTKVGPMVKHLKPGDRVAIEPGVPREIDEFCKIGRY 153

Query: 125 NLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTT 184
           NL P+I F ATPP DG+L R+  H A +CY+LP+SV+ EEGA+ EPLSV ++A RR   +
Sbjct: 154 NLTPSIFFCATPPDDGNLCRFYKHSADFCYKLPDSVTFEEGALIEPLSVGIYACRRGSVS 213

Query: 185 IGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEH 244
           +G+ VLV GAGPIG++  +VAKA GAS +VV D+   RLA A+   GAD  I       H
Sbjct: 214 LGNKVLVCGAGPIGIVTLLVAKAMGASQVVVIDLSASRLAKAK-EVGADFTIQVAKETPH 272

Query: 245 DAALVVQQALDGAQADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASS 304
           D A  V+  L G++ ++ ++C G ES+++  ++    GG + +VGMG   +++PLV A+ 
Sbjct: 273 DIAKKVESVL-GSKPEVTIECTGAESSVQTGIYATHSGGTLVVVGMGPEMINLPLVHAAV 331

Query: 305 REIDIFGVFRYSNTYPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANG-A 363
           RE+DI GVFRY NT+P  +++LAS  +NVKPL+THRF       LE A E   TA  G  
Sbjct: 332 REVDIKGVFRYCNTWPMAVSMLASKTLNVKPLVTHRF------PLEKAVEAFETAKKGLG 385

Query: 364 VKVML 368
           +KVM+
Sbjct: 386 LKVMI 390

emb|CAH93013.1| hypothetical protein [Pongo pygmaeus]
(357 aa)

Score: 308 bits (788), Expect: 2.04346e-82
Length: 340, Idn/Pos/Gap = 164/222/9 (48%/65%/2%)

Query:  30 PRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVV  89
           P +LR+    +P P P EV L+M  VGICGSDVHYW  G  G F +  PM++GHE++G V
Sbjct:  17 PGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEDGRIGNFIVKKPMVLGHEASGTV  76

Query:  90 EALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHP 149
           E +G+ V  L+ GDRVA+EPG P    + C+ GRYNL P+I F ATPP DG+L R+  H 
Sbjct:  77 EKVGSLVKHLKPGDRVAIEPGAPRENDEFCKIGRYNLSPSIFFCATPPDDGNLCRFYKHN 136

Query: 150 AAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFG 209
           AA+CY+LP++V+ EEGAM EPLSV +HA RR G T+G  VLV GAGPIG++  +VAKA G
Sbjct: 137 AAFCYKLPDNVTFEEGAMIEPLSVGIHACRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMG 196

Query: 210 ASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLE 269
           A+ +VVTD+   RL+ A+   GAD V+        + A  V+  L G + ++ ++C G  
Sbjct: 197 AAQVVVTDLSATRLSKAK-EIGADLVLQISKESPQEIARKVEGLL-GCKPEVTIECTGAG 254

Query: 270 STMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASG 329
           ++++  ++    GG + LVG+GS    +PL+ A+ RE+DI GVFRY NT+P  I++LAS 
Sbjct: 255 ASIQAGIYATHSGGTLVLVGLGSEMTTIPLLHAAIREVDIKGVFRYCNTWPVAISMLASK 314

Query: 330 RVNVKPLITHRFMGLEESSLEAAFETARTAANG-AVKVML 368
            VNVKPLITHRF       LE A E   T   G  +K+ML
Sbjct: 315 SVNVKPLITHRF------PLEKALEAFETFKKGLGLKIML 348

sp|P27867|DHSO_RAT Sorbitol dehydrogenase (L-iditol 2-dehydrogenase)
(399 aa)

Score: 307 bits (786), Expect: 3.45665e-82
Length: 365, Idn/Pos/Gap = 168/234/10 (46%/64%/2%)

Query:   5 ETELEESDAGSVLNEKANPCGVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHY  64
           +T  +ESD  +    + N   V+  P ++R+    +P   P +V L+M  VGICGSDVHY
Sbjct:  35 DTSKQESDMAAPAKGE-NLSLVVHGPGDIRLENYPIPELGPNDVLLKMHSVGICGSDVHY  93

Query:  65 WWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRY 124
           W HG  G F +  PM++GHE+AG V  +G  V  L+ GDRVA+EPGVP    + C+ GRY
Sbjct:  94 WEHGRIGDFVVKKPMVLGHEAAGTVTKVGPMVKHLKPGDRVAIEPGVPREIDEFCKIGRY 153

Query: 125 NLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTT 184
           NL P+I F ATPP DG+L R+  H A +CY+LP+SV+ EEGA+ EPLSV ++A RR   +
Sbjct: 154 NLTPSIFFCATPPDDGNLCRFYKHSADFCYKLPDSVTFEEGALIEPLSVGIYACRRGSVS 213

Query: 185 IGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEH 244
           +G+ VLV GAGPIG++  +VAKA GAS +VV D+   RLA A+   GAD  I       H
Sbjct: 214 LGNKVLVCGAGPIGIVTLLVAKAMGASQVVVIDLSASRLAKAK-EVGADFTIQVAKETPH 272

Query: 245 DAALVVQQALDGAQADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASS 304
           D A  V+  L G++ ++ ++C G ES+++  ++    GG + +VGMG   +++PLV A+ 
Sbjct: 273 DIAKKVESVL-GSKPEVTIECTGAESSVQDGIYATHSGGTLVVVGMGPEMINLPLVHAAV 331

Query: 305 REIDIFGVFRYSNTYPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANG-A 363
           RE+DI GVFRY NT+P  +++LAS  +NVKPL+THRF       LE A E   TA  G  
Sbjct: 332 REVDIKGVFRYCNTWPMAVSMLASKTLNVKPLVTHRF------PLEKAVEAFETAKKGLG 385

Query: 364 VKVML 368
           +KVM+
Sbjct: 386 LKVMI 390

gb|AAH88398.1| Sord protein [Rattus norvegicus]
(384 aa)

Score: 306 bits (785), Expect: 5.07391e-82
Length: 365, Idn/Pos/Gap = 168/234/10 (46%/64%/2%)

Query:   5 ETELEESDAGSVLNEKANPCGVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHY  64
           +T  +ESD  +    + N   V+  P ++R+    +P   P +V L+M  VGICGSDVHY
Sbjct:  20 DTSKQESDMAAPAKGE-NLSLVVHGPGDIRLENYPIPELGPNDVLLKMHSVGICGSDVHY  78

Query:  65 WWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRY 124
           W HG  G F +  PM++GHE+AG V  +G  V  L+ GDRVA+EPGVP    + C+ GRY
Sbjct:  79 WEHGRIGDFVVKKPMVLGHEAAGTVTKVGPMVKHLKPGDRVAIEPGVPREIDEFCKIGRY 138

Query: 125 NLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTT 184
           NL P+I F ATPP DG+L R+  H A +CY+LP+SV+ EEGA+ EPLSV ++A RR   +
Sbjct: 139 NLTPSIFFCATPPDDGNLCRFYKHSADFCYKLPDSVTFEEGALIEPLSVGIYACRRGSVS 198

Query: 185 IGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEH 244
           +G+ VLV GAGPIG++  +VAKA GAS +VV D+   RLA A+   GAD  I       H
Sbjct: 199 LGNKVLVCGAGPIGIVTLLVAKAMGASQVVVIDLSASRLAKAK-EVGADFTIQVAKETPH 257

Query: 245 DAALVVQQALDGAQADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASS 304
           D A  V+  L G++ ++ ++C G ES+++  ++    GG + +VGMG   +++PLV A+ 
Sbjct: 258 DIAKKVESVL-GSKPEVTIECTGAESSVQTGIYATHSGGTLVVVGMGPEMINLPLVHAAV 316

Query: 305 REIDIFGVFRYSNTYPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANG-A 363
           RE+DI GVFRY NT+P  +++LAS  +NVKPL+THRF       LE A E   TA  G  
Sbjct: 317 REVDIKGVFRYCNTWPMAVSMLASKTLNVKPLVTHRF------PLEKAVEAFETAKKGLG 370

Query: 364 VKVML 368
           +KVM+
Sbjct: 371 LKVMI 375

pdb|1PL6|D Chain D, Human SdhNADHINHIBITOR COMPLEX
pdb|1PL6|C Chain C, Human SdhNADHINHIBITOR COMPLEX
pdb|1PL6|B Chain B, Human SdhNADHINHIBITOR COMPLEX
pdb|1PL6|A Chain A, Human SdhNADHINHIBITOR COMPLEX
(356 aa)

Score: 305 bits (782), Expect: 1.12096e-81
Length: 333, Idn/Pos/Gap = 160/216/8 (48%/64%/2%)

Query:  30 PRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVV  89
           P +LR+    +P P P EV L+   VGICGSDVHYW +G  G F +  P ++GHE++G V
Sbjct:  16 PGDLRLENYPIPEPGPNEVLLRXHSVGICGSDVHYWEYGRIGNFIVKKPXVLGHEASGTV  75

Query:  90 EALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHP 149
           E +G+ V  L+ GDRVA+EPG P    + C+ GRYNL P+I F ATPP DG+L R+  H 
Sbjct:  76 EKVGSSVKHLKPGDRVAIEPGAPRENDEFCKXGRYNLSPSIFFCATPPDDGNLCRFYKHN 135

Query: 150 AAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFG 209
           AA+CY+LP++V+ EEGA+ EPLSV +HA RR G T+G  VLV GAGPIG +  +VAKA G
Sbjct: 136 AAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGAGPIGXVTLLVAKAXG 195

Query: 210 ASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLE 269
           A+ +VVTD+   RL+ A+   GAD V+        + A  V+  L G + ++ ++C G E
Sbjct: 196 AAQVVVTDLSATRLSKAK-EIGADLVLQISKESPQEIARKVEGQL-GCKPEVTIECTGAE 253

Query: 270 STMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASG 329
           ++++  ++  R GG + LVG+GS    VPL+ A+ RE+DI GVFRY NT+P  I+ LAS 
Sbjct: 254 ASIQAGIYATRSGGTLVLVGLGSEXTTVPLLHAAIREVDIKGVFRYCNTWPVAISXLASK 313

Query: 330 RVNVKPLITHRFMGLEESSLEAAFETARTAANG 362
            VNVKPL+THRF       LE A E   T   G
Sbjct: 314 SVNVKPLVTHRF------PLEKALEAFETFKKG 340

ref|NP_058748.1| sorbitol dehydrogenase [Rattus norvegicus]
emb|CAA41761.1| sorbitol dehydrogenase [Rattus norvegicus]
(357 aa)

Score: 305 bits (782), Expect: 1.18838e-81
Length: 340, Idn/Pos/Gap = 162/223/9 (47%/65%/2%)

Query:  30 PRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVV  89
           P ++R+    +P   P +V L+M  VGICGSDVHYW HG  G F +  PM++GHE+AG V
Sbjct:  17 PGDIRLENYPIPELGPNDVLLKMHSVGICGSDVHYWEHGRIGDFVVKKPMVLGHEAAGTV  76

Query:  90 EALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHP 149
             +G  V  L+ GDRVA+EPGVP    + C+ GRYNL P+I F ATPP DG+L R+  H 
Sbjct:  77 TKVGPMVKHLKPGDRVAIEPGVPREIDEFCKIGRYNLTPSIFFCATPPDDGNLCRFYKHS 136

Query: 150 AAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFG 209
           A +CY+LP+SV+ EEGA+ EPLSV ++A RR   ++G+ VLV GAGPIG++  +VAKA G
Sbjct: 137 ADFCYKLPDSVTFEEGALIEPLSVGIYACRRGSVSLGNKVLVCGAGPIGIVTLLVAKAMG 196

Query: 210 ASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLE 269
           AS +VV D+   RLA A+   GAD  I       HD A  V+  L G++ ++ ++C G E
Sbjct: 197 ASQVVVIDLSASRLAKAK-EVGADFTIQVAKETPHDIAKKVESVL-GSKPEVTIECTGAE 254

Query: 270 STMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASG 329
           S+++  ++    GG + +VGMG   +++PLV A+ RE+DI GVFRY NT+P  +++LAS 
Sbjct: 255 SSVQDGIYATHSGGTLVVVGMGPEMINLPLVHAAVREVDIKGVFRYCNTWPMAVSMLASK 314

Query: 330 RVNVKPLITHRFMGLEESSLEAAFETARTAANG-AVKVML 368
            +NVKPL+THRF       LE A E   TA  G  +KVM+
Sbjct: 315 TLNVKPLVTHRF------PLEKAVEAFETAKKGLGLKVMI 348

gb|AAP69754.1| NAD-dependent sorbitol dehydrogenase 5 [Malus x domestica]
(284 aa)

Score: 303 bits (777), Expect: 3.98459e-81
Length: 280, Idn/Pos/Gap = 145/200/2 (51%/71%/0%)

Query:  40 VPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSL  99
           +PA  P +V+++++ VGICGSDVHY     C  F + +PM+IGHE AG+V+ +G+ V  L
Sbjct:   6 LPAIGPNDVQIRIKAVGICGSDVHYLKTMKCADFEVKEPMVIGHECAGIVDKVGSEVKHL  65

Query: 100 QVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPES 159
             GDRVA+EPG+ C  CQ+C+ GRYNLCP++KFFATPPV G+LA  + HPA  C++LPE+
Sbjct:  66 VPGDRVAVEPGISCAHCQQCKGGRYNLCPDMKFFATPPVHGALANQIVHPADLCFKLPEN 125

Query: 160 VSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDID 219
           VSLEEGAMCEPLSV VHA RRA     + VL++GAGPIGL++ + A+AFGA  IV+ D+D
Sbjct: 126 VSLEEGAMCEPLSVGVHACRRANVGPETTVLIIGAGPIGLVSVLAARAFGAPRIVIVDMD 185

Query: 220 DRRLAFAETHAGADAV-INTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHV 278
           D+RLA A++    D V ++T+  D  D    +++A+  ++ D+  DC G   TM   ++ 
Sbjct: 186 DKRLAMAKSLGADDTVKVSTKMEDLDDEVAEIKKAMI-SEVDVTFDCVGFNKTMATGLNA 244

Query: 279 VRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNT 318
            RPGG++CLVGMG   M VPL  A++RE+D+ GVFRY NT
Sbjct: 245 TRPGGKVCLVGMGHGLMTVPLTPAAAREVDVVGVFRYKNT 284

gb|AAH30875.1| Unknown (protein for MGC:31355) [Mus musculus]
gb|AAH92291.1| Sorbitol dehydrogenase 1 [Mus musculus]
ref|NP_666238.1| sorbitol dehydrogenase 1 [Mus musculus]
gb|AAH24124.1| Sorbitol dehydrogenase 1 [Mus musculus]
dbj|BAB29695.1| unnamed protein product [Mus musculus]
dbj|BAB23478.1| unnamed protein product [Mus musculus]
(357 aa)

Score: 301 bits (772), Expect: 1.59187e-80
Length: 340, Idn/Pos/Gap = 159/222/9 (46%/65%/2%)

Query:  30 PRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVV  89
           P ++R+    +P   P +V L+M  VGICGSDVHYW HG  G F +  PM++GHE+AG V
Sbjct:  17 PGDIRLENYPIPELGPNDVLLKMHSVGICGSDVHYWEHGRIGDFVVKKPMVLGHEAAGTV  76

Query:  90 EALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHP 149
             +G  V  L+ GDRVA+EPGVP    + C+ GRYNL P I F ATPP DG+L R+  H 
Sbjct:  77 TKVGELVKHLKPGDRVAIEPGVPREVDEYCKIGRYNLTPTIFFCATPPDDGNLCRFYKHN 136

Query: 150 AAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFG 209
           A +CY+LP+SV+ EEGA+ EPLSV ++A RR   ++G+ VLV GAGP+G++  +VAKA G
Sbjct: 137 ADFCYKLPDSVTFEEGALIEPLSVGIYACRRGSVSLGNKVLVCGAGPVGMVTLLVAKAMG 196

Query: 210 ASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLE 269
           A+ +VVTD+   RL  A+   GAD  I        + A  V+  L G++ ++ ++C G E
Sbjct: 197 AAQVVVTDLSASRLTKAK-EVGADFTIQVGKETPQEIASKVESLL-GSKPEVTIECTGAE 254

Query: 270 STMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASG 329
           S+++  ++    GG + +VGMG+  +++PLV A+ RE+DI GVFRY NT+P  I++LAS 
Sbjct: 255 SSVQTGIYATHSGGTLVIVGMGAEMVNLPLVHAAIREVDIKGVFRYCNTWPMAISMLASK 314

Query: 330 RVNVKPLITHRFMGLEESSLEAAFETARTAANG-AVKVML 368
            +NVKPL+THRF       LE A E   TA  G  +KVM+
Sbjct: 315 TLNVKPLVTHRF------PLEKAVEAFETAKKGVGLKVMI 348

sp|Q64442|DHSO_MOUSE Sorbitol dehydrogenase (L-iditol 2-dehydrogenase)
(375 aa)

Score: 300 bits (769), Expect: 3.20844e-80
Length: 340, Idn/Pos/Gap = 159/222/9 (46%/65%/2%)

Query:  30 PRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVV  89
           P ++R+    +P   P +V L+M  VGICGSDVHYW HG  G F +  PM++GHE+AG V
Sbjct:  35 PGDIRLENYPIPELGPNDVLLKMHSVGICGSDVHYWEHGRIGDFVVKKPMVLGHEAAGTV  94

Query:  90 EALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHP 149
             +G  V  L+ GDRVA+EPGVP    + C+ GRYNL P I F ATPP DG+L R+  H 
Sbjct:  95 TKVGELVKHLKPGDRVAIEPGVPREVDEYCKIGRYNLTPTIFFCATPPDDGNLCRFYKHN 154

Query: 150 AAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFG 209
           A +CY+LP+SV+ EEGA+ EPLSV ++A RR   ++G+ VLV GAGP+G++  +VAKA G
Sbjct: 155 ADFCYKLPDSVTFEEGALIEPLSVGIYACRRGSVSLGNKVLVCGAGPVGMVTLLVAKAMG 214

Query: 210 ASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLE 269
           A+ +VVTD+   RL  A+   GAD  I        + A  V+  L G++ ++ ++C G E
Sbjct: 215 AAQVVVTDLSASRLTKAK-EVGADFTIQVGKETPQEIASKVESLL-GSKPEVTIECTGAE 272

Query: 270 STMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASG 329
           S+++  ++    GG + +VGMG+  +++PLV A+ RE+DI GVFRY NT+P  I++LAS 
Sbjct: 273 SSVQTGIYATHSGGTLVIVGMGAEMVNLPLVHAAIREVDIKGVFRYCNTWPMAISMLASK 332

Query: 330 RVNVKPLITHRFMGLEESSLEAAFETARTAANG-AVKVML 368
            +NVKPL+THRF       LE A E   TA  G  +KVM+
Sbjct: 333 TLNVKPLVTHRF------PLEKAVEAFETAKKGVGLKVMI 366

gb|AAA79043.1| sorbitol dehydrogenase precursor [Mus musculus domesticus]
(375 aa)

Score: 299 bits (765), Expect: 1.04047e-79
Length: 340, Idn/Pos/Gap = 158/222/9 (46%/65%/2%)

Query:  30 PRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVV  89
           P ++R+    +P   P +V L+M  VGICGSD+HYW HG  G F +  PM++GHE+AG V
Sbjct:  35 PGDIRLENYPIPELGPNDVLLKMHSVGICGSDLHYWEHGRIGDFVVKKPMVLGHEAAGTV  94

Query:  90 EALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHP 149
             +G  V  L+ GDRVA+EPGVP    + C+ GRYNL P I F ATPP DG+L R+  H 
Sbjct:  95 TKVGELVKHLKPGDRVAIEPGVPREVDEYCKIGRYNLTPTIFFCATPPDDGNLCRFYKHN 154

Query: 150 AAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFG 209
           A +CY+LP+SV+ EEGA+ EPLSV ++A RR   ++G+ VLV GAGP+G++  +VAKA G
Sbjct: 155 ADFCYKLPDSVTFEEGALIEPLSVGIYACRRGSVSLGNKVLVCGAGPVGMVTLLVAKAMG 214

Query: 210 ASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLE 269
           A+ +VVTD+   RL  A+   GAD  I        + A  V+  L G++ ++ ++C G E
Sbjct: 215 AAQVVVTDLSASRLTKAK-EVGADFTIQVGKETPQEIASKVESLL-GSKPEVTIECTGAE 272

Query: 270 STMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASG 329
           S+++  ++    GG + +VGMG+  +++PLV A+ RE+DI GVFRY NT+P  I++LAS 
Sbjct: 273 SSVQSGIYATHSGGTLVIVGMGAEMVNLPLVHAAIREVDIKGVFRYCNTWPMAISMLASK 332

Query: 330 RVNVKPLITHRFMGLEESSLEAAFETARTAANG-AVKVML 368
            +NVKPL+THRF       LE A E   TA  G  +KVM+
Sbjct: 333 TLNVKPLVTHRF------PLEKAVEAFETAKKGVGLKVMI 366

gb|EAA61897.1| hypothetical protein AN9064.2 [Aspergillus nidulans FGSC A4]
ref|XP_413201.1| hypothetical protein AN9064.2 [Aspergillus nidulans FGSC A4]
(359 aa)

Score: 295 bits (756), Expect: 1.27152e-78
Length: 342, Idn/Pos/Gap = 154/220/9 (45%/64%/2%)

Query:  34 RVMLRSVPAP---APGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVE  90
           RV     P P   +P +V + ++  GICGSDVHYW HG+ G F + +PM++GHES+G+V 
Sbjct:  20 RVKFEDRPIPKLKSPHDVIVNVKYTGICGSDVHYWDHGAIGQFVVKEPMVLGHESSGIVT  79

Query:  91 ALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPA 150
            +G+ VTSL+VGD VA+EPG+PC +C+ C+ G+YNLC  + F ATPP DG+LA+Y   P 
Sbjct:  80 QIGSAVTSLKVGDHVAMEPGIPCRRCEPCKAGKYNLCEKMAFAATPPYDGTLAKYYTLPE 139

Query: 151 AWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGA 210
            +CY+LPES+SL EGA+ EPL VAVH  R+A  T G  V+V GAGP+GLL C VAKAFGA
Sbjct: 140 DFCYKLPESISLPEGALMEPLGVAVHIVRQANVTPGQTVVVFGAGPVGLLCCAVAKAFGA 199

Query: 211 SIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLES 270
             I+  DI   RL FA+  A       ++     +A  ++ +   G  AD+A+D +G+E 
Sbjct: 200 IRIIAVDIQKPRLDFAKKFAATATFEPSKAPATENATRMIAENDLGRGADVAIDASGVEP 259

Query: 271 TMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRY-SNTYPTCIALLASG 329
           ++   +HV+RPGG     GMG S M+ P++ A ++E++I G FRY S  Y   + L+ASG
Sbjct: 260 SVHTGIHVLRPGGTYVQGGMGRSEMNFPIMAACTKELNIKGSFRYGSGDYKLAVQLVASG 319

Query: 330 RVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLTIP 371
           ++NVK LIT   +  E++  E AF+  +T     +K ++  P
Sbjct: 320 QINVKELITG-IVKFEDA--EQAFKDVKTGK--GIKTLIAGP 356

emb|CAH69384.1| xylitol dehydrogenase [Aspergillus niger]
(358 aa)

Score: 293 bits (750), Expect: 5.0798e-78
Length: 339, Idn/Pos/Gap = 153/220/9 (45%/64%/2%)

Query:  34 RVMLRSVPAPA---PGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVE  90
           RV     P P    P +V + +R  GICGSDVHYW HGS G F + DPM++GHES+GVV 
Sbjct:  20 RVKFEDRPIPEINNPHDVLVNVRFTGICGSDVHYWEHGSIGQFIVKDPMVLGHESSGVVS  79

Query:  91 ALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPA 150
            +G+ VTSL+VGD VA+EPG+PC +C+ C+ G+YNLC  + F ATPP DG+LA+Y   P 
Sbjct:  80 KVGSAVTSLKVGDCVAMEPGIPCRRCEPCKAGKYNLCVKMAFAATPPYDGTLAKYYVLPE 139

Query: 151 AWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGA 210
            +CY+LPES++L+EGA+ EPLSVAVH  ++AG   G  V+V GAGP+GLL C VAKA+GA
Sbjct: 140 DFCYKLPESITLQEGAIMEPLSVAVHIVKQAGINPGQSVVVFGAGPVGLLCCAVAKAYGA 199

Query: 211 SIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLES 270
           S ++  DI   RL FA+ +A        +     +A  ++ +   G+ AD+A+D +G E 
Sbjct: 200 SKVIAVDIQKGRLDFAKKYAATATFEPAKAAALENAQRIITENDLGSGADVAIDASGAEP 259

Query: 271 TMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRY-SNTYPTCIALLASG 329
           ++   +HV+R GG     GMG S +  P++ A ++E+++ G FRY S  Y   ++L+++G
Sbjct: 260 SVHTGIHVLRAGGTYVQGGMGRSEITFPIMAACTKELNVKGSFRYGSGDYKLAVSLVSAG 319

Query: 330 RVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVML 368
           +VNVK LIT   +  E++  E AFE  R  A   +K ++
Sbjct: 320 KVNVKELITG-VVKFEDA--ERAFEEVR--AGKGIKTLI 353

emb|CAA94842.1| Hypothetical protein R04B5.6 [Caenorhabditis elegans]
ref|NP_505590.1| sorbitol dehydrogenase (5K567) [Caenorhabditis elegans]
pir||T23890 hypothetical protein R04B5.6 - Caenorhabditis elegans
(347 aa)

Score: 288 bits (737), Expect: 1.70373e-76
Length: 347, Idn/Pos/Gap = 152/228/6 (43%/65%/1%)

Query:  22 NPCGVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMII  81
           N   VL    +LR+    +  P P +V +++  VGICGSDVH+  HG+ G F + +PM++
Sbjct:   5 NLSAVLYGINDLRLEQAPISKPGPRQVLVKINTVGICGSDVHFLTHGAIGSFVVKEPMVL  64

Query:  82 GHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGS 141
           GHES+GVV  +G+ V   +VGDR+A+EPG+PC  C+ C+ GRYNLCP+++FFATPPV+G+
Sbjct:  65 GHESSGVVSEIGSEVKGFKVGDRIAMEPGLPCKLCEHCKIGRYNLCPDMRFFATPPVNGA 124

Query: 142 LARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLN 201
           L+R+V H A +C++LP+++S E+GA+ EPLSVA+ A RR    +G  +LVLGAGPIG+LN
Sbjct: 125 LSRFVVHDADFCFKLPDNLSFEDGALLEPLSVAIQACRRGTVQMGQKILVLGAGPIGVLN 184

Query: 202 CMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADI 261
            + AKA GAS +V+TD++D RLA A    GADA IN       +    + +A    Q  +
Sbjct: 185 LLTAKAIGASKVVITDLNDERLALARL-LGADATINVMGKRSDEVRSEIIKAFGDQQPHV 243

Query: 262 ALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPT 321
           +++C G++  +  A+   R GG + LVG+G+  + +PL+ + +RE+D+ G FR +N Y T
Sbjct: 244 SIECTGVQPCVETAIMTTRSGGVVVLVGLGAERVEIPLIQSPTREVDLRGTFRSANCYST 303

Query: 322 CIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVML 368
            I L++SG++++  L T     LEE SLEA     RT     +KV +
Sbjct: 304 AIELISSGKLDLSGL-TRAHYKLEE-SLEA---FKRTQNGDVIKVFI 345

gb|EAA08811.2| ENSANGP00000011378 [Anopheles gambiae str. PEST]
ref|XP_313337.2| ENSANGP00000011378 [Anopheles gambiae str. PEST]
(358 aa)

Score: 286 bits (731), Expect: 8.11003e-76
Length: 347, Idn/Pos/Gap = 166/222/5 (47%/63%/1%)

Query:  22 NPCGVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMII  81
           N  GV+    + RV    +P P   EV L+M CVGICGSDVHY  HG  G ++L D M++
Sbjct:   4 NLAGVVHGVEDFRVEEIPMPRPRDHEVLLEMDCVGICGSDVHYVSHGGFGDYKLKDKMVL  63

Query:  82 GHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGS 141
           GHES+GVV A+GA VTSLQVGDRVA+EP + C  C+ C+ GRYN+CP   +  T    G+
Sbjct:  64 GHESSGVVVAVGADVTSLQVGDRVAIEPAIGCRTCRHCKAGRYNICPQGVYCVTTG-HGN 122

Query: 142 LARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLN 201
           L  Y  H A  C++LP +V++EEGA+ EPL+V VH  RR G  IGS VLVLGAGPIGL+ 
Sbjct: 123 LCNYYTHAADCCFKLPANVTMEEGALLEPLAVGVHCCRRGGVGIGSTVLVLGAGPIGLVT 182

Query: 202 CMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADI 261
            +VAKA GA+ + V D+ +R+L  A+T  GADA +     D  D  +    AL G   DI
Sbjct: 183 LLVAKAMGAAKVCVIDLVERKLELAKT-LGADATLAVSGHDTQDEIVKRIHALLGTAPDI 241

Query: 262 ALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPT 321
           +++C G E+ ++L +    PGG + LVG+G+    VP+  A  REIDI   FRY+N YP 
Sbjct: 242 SIECTGAEACVQLGIEATVPGGVVTLVGIGAIQQRVPITTALVREIDIRTAFRYANCYPA 301

Query: 322 CIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVML 368
            +A++A+G ++   LITH +  L+ES  + AF TAR    GAVKVM+
Sbjct: 302 ALAMVANGTIDALKLITHHYE-LQES--DQAFNTARYGLGGAVKVMI 345

gb|EAL17790.1| hypothetical protein CNBL3030 [Cryptococcus neoformans var. neoformans B-3501A]
gb|AAW45159.1| L-arabinitol 4-dehydrogenase, putative [Cryptococcus neoformans var. neoformans JEC21]
ref|XP_572466.1| L-arabinitol 4-dehydrogenase, putative [Cryptococcus neoformans var. neoformans JEC21]
(392 aa)

Score: 283 bits (724), Expect: 6.21143e-75
Length: 329, Idn/Pos/Gap = 150/207/6 (45%/62%/1%)

Query:  43 PAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRL-HDPMIIGHESAGVVEALGAGVTSLQV 101
           P PGEV + +R  GICGSDVH+W HG  GP  +  D    GHESAG + A+G GVT  QV
Sbjct:  65 PGPGEVTIHVRATGICGSDVHFWKHGHIGPTMIVTDECGAGHESAGEIVAIGEGVTQWQV 124

Query: 102 GDRVALEPGVPC--LQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPES 159
           GDRVA+E GVPC    C+ CR GRYN CP   FF+TPP  G+L RY  HPAAWC+RL ++
Sbjct: 125 GDRVAIEAGVPCGLASCEPCRTGRYNACPADVFFSTPPYHGTLTRYHNHPAAWCHRLADN 184

Query: 160 VSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDID 219
           +S EEG++CEPL+VA+    RAG  +G  +++ GAGPIGL+  + A A G + IV+TD+ 
Sbjct: 185 MSYEEGSLCEPLTVALAGIDRAGVRLGDPIVICGAGPIGLVTLLAAHAAGCTPIVITDLF 244

Query: 220 DRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVV 279
             RL FA+        +      + +      + + G Q  IALDC G+ES++R A+  V
Sbjct: 245 ASRLEFAKKLLPTVKTVLIEKTAKPEEVAKQIKDVAGMQLSIALDCTGVESSIRSAIFSV 304

Query: 280 RPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASGRVNVKPLITH 339
           + GG++ ++G+G S    P    S+REID+   +RY+N YP  I L++ G V++KPL+TH
Sbjct: 305 KFGGKVFVIGVGPSEQSYPFGYCSAREIDLQFQYRYNNQYPKAIRLISGGLVDLKPLVTH 364

Query: 340 RFMGLEESSLEAAFETARTAANGAVKVML 368
           RF  L+E+    AF  A   + GA+KV +
Sbjct: 365 RFT-LKEAV--KAFHVAADPSQGAIKVQI 390

dbj|BAC75870.2| xylitol dehydrogenase [Aspergillus oryzae]
(358 aa)

Score: 281 bits (719), Expect: 2.2639e-74
Length: 293, Idn/Pos/Gap = 136/198/1 (46%/67%/0%)

Query:  47 EVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGDRVA 106
           +V + +R  GICGSDVHYW HGS G F + DPM++GHES+GV+  +G+ VT+L+VGD VA
Sbjct:  36 DVLVDVRFTGICGSDVHYWEHGSIGQFVVKDPMVLGHESSGVISKVGSAVTTLKVGDHVA  95

Query: 107 LEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPESVSLEEGA 166
           +EPG+PC +C+ C+EG+YNLC  + F ATPP DG+LA+Y   P  +CY+LPE+++L+E A
Sbjct:  96 MEPGIPCRRCEPCKEGKYNLCEKMAFAATPPYDGTLAKYYVLPEDFCYKLPENINLQEAA 155

Query: 167 MCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFA 226
           + EPLSVAVH  ++A    G  V+V GAGP+GLL C VA+AFG+  ++  DI   RL FA
Sbjct: 156 VMEPLSVAVHIVKQANVAPGQSVVVFGAGPVGLLCCAVARAFGSPKVIAVDIQKGRLEFA 215

Query: 227 ETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVVRPGGRIC 286
           + +A       ++     +A  +V +   G  ADI +D +G E ++   +HV+RPGG   
Sbjct: 216 KKYAATAIFEPSKVSALENAERIVNENDLGRGADIVIDASGAEPSVHTGIHVLRPGGTYV 275

Query: 287 LVGMGSSAMHVPLVDASSREIDIFGVFRY-SNTYPTCIALLASGRVNVKPLIT 338
             GMG + +  P++ A ++E+++ G FRY S  Y   + L+ASG+V+VK LIT
Sbjct: 276 QGGMGRNEITFPIMAACTKELNVRGSFRYGSGDYKLAVNLVASGKVSVKELIT 328

gb|EAA53659.1| hypothetical protein MG07936.4 [Magnaporthe grisea 70-15]
ref|XP_368032.1| hypothetical protein MG07936.4 [Magnaporthe grisea 70-15]
(664 aa)

Score: 279 bits (714), Expect: 8.53132e-74
Length: 367, Idn/Pos/Gap = 156/217/24 (42%/59%/6%)

Query:  26 VLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHES  85
           +L  P++LRV  R++PAPA GEV++ +R  GICGSD+HY+ HG+ G F++ +P+ +GHES
Sbjct: 296 LLYGPKDLRVEERTIPAPAAGEVQVSIRATGICGSDMHYYVHGANGDFKVREPLSLGHES 355

Query:  86 AGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFAT----PPVDGS 141
           AGVVEA+G  VT L+VGDRVA+E G+ C  C  C+ GRYNLC  +KF ++    P   G+
Sbjct: 356 AGVVEAVGPDVTDLKVGDRVAVEVGIACDDCALCKSGRYNLCKGMKFRSSAKIFPHFQGT 415

Query: 142 LARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLN 201
           L   + HPA   Y+LP+S SL EGA+ EPL VA+H  +RAG   G   LVLGAG +GLL 
Sbjct: 416 LQDRINHPARLTYKLPDSASLAEGALLEPLGVAIHGVKRAGEQKGKTALVLGAGAVGLLT 475

Query: 202 CMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVI--------NTRDLDE------HDAA 247
             V +  G   I + DI   R+ FA  H  AD  +         T   DE        AA
Sbjct: 476 AAVLRVEGIESIAIADIVPERVQFAVAHGFADKAVVVPSKRLPPTASADEKLALARETAA 535

Query: 248 LVVQQALDGAQADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREI 307
           L+ ++   G + D   +C G+ES ++ A++   PGGR+ ++GMG+    +PL  A+ RE+
Sbjct: 536 LLTREGNGGDEYDTTFECTGVESCVQAAIYATGPGGRVMMIGMGTPVQTLPLGAAALREV 595

Query: 308 DIFGVFRYSNTYPTCIALLASGRVNVKP----LITHRFMGLEESSLEAAFETARTAANGA 363
           D+ GVFRY+NTYP  I LLA    N  P    L T    GL+ +  E AF  A    +  
Sbjct: 596 DLLGVFRYANTYPRGIELLAGRESNGMPDIGLLATQNVKGLDRA--EDAFAIAAKPVDAD 653

Query: 364 VKVMLTI 370
            K++L +
Sbjct: 654 GKLVLKV 660

gb|AAW44418.1| L-arabinitol 4-dehydrogenase, putative [Cryptococcus neoformans var. neoformans JEC21]
ref|XP_571725.1| L-arabinitol 4-dehydrogenase, putative [Cryptococcus neoformans var. neoformans JEC21]
(392 aa)

Score: 279 bits (713), Expect: 1.13297e-73
Length: 367, Idn/Pos/Gap = 154/215/6 (41%/58%/1%)

Query:   5 ETELEESDAGSVLNEKANPCGVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHY  64
           E +    DA  + + K N         E+ ++ +    P PGEV + +R  GICGSDVH+
Sbjct:  27 EFQTLSEDAPELSDPKLNIACAYNPAHEIHMVKKPRFEPGPGEVTIHVRATGICGSDVHF  86

Query:  65 WWHGSCGPFRL-HDPMIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPC--LQCQRCRE 121
           W HG  GP  +  D    GHESAG + A+G GV   QVGDRVA+E GVPC    C  CR 
Sbjct:  87 WKHGHIGPTMIVTDECGAGHESAGEIVAVGEGVAQWQVGDRVAVEAGVPCGLASCDPCRT 146

Query: 122 GRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRA 181
           GRYN CP + FF+TPP  G+L RY  HPAAWC+RL ++VS EEG++CEPL+VA+    RA
Sbjct: 147 GRYNACPAVVFFSTPPYHGTLTRYHNHPAAWCHRLADNVSYEEGSLCEPLAVALAGLDRA 206

Query: 182 GTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDL 241
           G  +G  + + GAGPIGL+  + A A G + IV+TD+   RL FA+        +     
Sbjct: 207 GVRLGDPIAICGAGPIGLVTLLAAHAAGCTPIVITDLFPSRLEFAKKLLPTVKTVQIEKT 266

Query: 242 DEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVD 301
            + +      +   G Q  +A DC G+ES++R A+  V+ GG++ ++G+G S    P   
Sbjct: 267 AKPEEVAKQIKGAAGMQLSLAFDCTGVESSIRSAIFSVKFGGKVFVIGVGPSEQSYPFGY 326

Query: 302 ASSREIDIFGVFRYSNTYPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAAN 361
            S+ EID+   +RY+N YP  I L+A G V++KPL+THRF  L+E+    AF  A   + 
Sbjct: 327 CSANEIDLQFQYRYNNQYPKAIRLVAGGLVDLKPLVTHRF-ALKEAV--KAFHVAADPSQ 383

Query: 362 GAVKVML 368
           GA+KV +
Sbjct: 384 GAIKVQI 390

emb|CAA89692.1| SOR1 [Saccharomyces cerevisiae]
gb|AAT93031.1| YJR159W [Saccharomyces cerevisiae]
sp|P35497|DHSO1_YEAST Sorbitol dehydrogenase 1 (L-iditol 2-dehydrogenase 1)
ref|NP_012693.1| Sor1p [Saccharomyces cerevisiae]
gb|AAA35027.1| sorbitol dehydrogenase
(357 aa)

Score: 278 bits (712), Expect: 1.24188e-73
Length: 330, Idn/Pos/Gap = 141/205/6 (42%/62%/1%)

Query:  17 LNEKANPCGVLVRPRELRVMLRSVPA-PAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRL  75
           +++ +NP  VL +  ++ +  R +P    P  V+L ++  GICGSD+HY+  G  G + L
Sbjct:   1 MSQNSNPAVVLEKVGDIAIEQRPIPTIKDPHYVKLAIKATGICGSDIHYYRSGGIGKYIL  60

Query:  76 HDPMIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFAT 135
             PM++GHES+G V  +G  VT ++VGDRVA+EPGVP       +EGRYNLCP++ F AT
Sbjct:  61 KAPMVLGHESSGQVVEVGDAVTRVKVGDRVAIEPGVPSRYSDETKEGRYNLCPHMAFAAT 120

Query: 136 PPVDGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAG 195
           PP+DG+L +Y   P  +  +LPE VS EEGA  EPLSV VH+N+ AG   G+ V+V GAG
Sbjct: 121 PPIDGTLVKYYLSPEDFLVKLPEGVSYEEGACVEPLSVGVHSNKLAGVRFGTKVVVFGAG 180

Query: 196 PIGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLD---EHDAALVVQQ 252
           P+GLL   VA+AFGA+ ++  D+ D +L  A+   GA    N+         D A  VQ+
Sbjct: 181 PVGLLTGAVARAFGATDVIFVDVFDNKLQRAKDF-GATNTFNSSQFSTDKAQDLADGVQK 239

Query: 253 ALDGAQADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGV 312
            L G  AD+  +C+G +  +  A+   + GG +  VGMG +  + P+ + S +E+ + G 
Sbjct: 240 LLGGNHADVVFECSGADVCIDAAVKTTKVGGTMVQVGMGKNYTNFPIAEVSGKEMKLIGC 299

Query: 313 FRYS-NTYPTCIALLASGRVNVKPLITHRF 341
           FRYS   Y   + L+A+G+VNVKPLITH+F
Sbjct: 300 FRYSFGDYRDAVNLVATGKVNVKPLITHKF 329

gb|EAL19517.1| hypothetical protein CNBG4640 [Cryptococcus neoformans var. neoformans B-3501A]
(392 aa)

Score: 278 bits (712), Expect: 1.37266e-73
Length: 367, Idn/Pos/Gap = 154/215/6 (41%/58%/1%)

Query:   5 ETELEESDAGSVLNEKANPCGVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHY  64
           E +    DA  + + K N         E+ ++ +    P PGEV + +R  GICGSDVH+
Sbjct:  27 EFQTLSEDAPELSDPKLNIACAYNPAHEIHMVKKPRFEPGPGEVTIHVRATGICGSDVHF  86

Query:  65 WWHGSCGPFRL-HDPMIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPC--LQCQRCRE 121
           W HG  GP  +  D    GHESAG + A+G GV   QVGDRVA+E GVPC    C  CR 
Sbjct:  87 WKHGHIGPTMIVTDECGAGHESAGEIVAVGEGVAQWQVGDRVAVEAGVPCGLASCDPCRT 146

Query: 122 GRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRA 181
           GRYN CP + FF+TPP  G+L RY  HPAAWC+RL ++VS EEG++CEPL+VA+    RA
Sbjct: 147 GRYNACPAVVFFSTPPYHGTLTRYHNHPAAWCHRLADNVSYEEGSLCEPLAVALAGLDRA 206

Query: 182 GTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDL 241
           G  +G  + + GAGPIGL+  + A A G + IV+TD+   RL FA+        +     
Sbjct: 207 GVRLGDPIAICGAGPIGLVTLLAAHAAGCTPIVITDLFPSRLEFAKKLLPTVKTVQIEKT 266

Query: 242 DEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVD 301
            + +      +   G Q  +A DC G+ES++R A+  V+ GG++ ++G+G S    P   
Sbjct: 267 AKPEEVAKQIKGAAGMQLSLAFDCTGVESSIRSAIFSVKFGGKVFVIGVGPSEQSYPFGY 326

Query: 302 ASSREIDIFGVFRYSNTYPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAAN 361
            S+ EID+   +RY+N YP  I L+A G V++KPL+THRF  L+E+    AF  A   + 
Sbjct: 327 CSANEIDLQFQYRYNNQYPKAIRLVAGGLVDLKPLVTHRF-ALKEAV--KAFHVAADPSQ 383

Query: 362 GAVKVML 368
           GA+KV +
Sbjct: 384 GAIKVQI 390

ref|YP_134460.1| zinc-binding dehydrogenase [Haloarcula marismortui ATCC 43049]
gb|AAV44754.1| zinc-binding dehydrogenase [Haloarcula marismortui ATCC 43049]
(343 aa)

Score: 278 bits (712), Expect: 1.51722e-73
Length: 315, Idn/Pos/Gap = 148/200/7 (46%/63%/2%)

Query:  25 GVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHE  84
            VLV P E  +  R  P+P P EV + +R VGICGSDVHY+ HG  G + + DP+++GHE
Sbjct:   4 AVLVEPTEFELEDRPRPSPGPDEVLVAVRDVGICGSDVHYYEHGRIGDYVVEDPLVLGHE  63

Query:  85 SAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLAR 144
           SAG V  +G  VT  + GDRVALEPGVPC +C  C+ G Y+LC +++F ATPP DG+   
Sbjct:  64 SAGKVVEVGENVTDHEPGDRVALEPGVPCRRCAHCKRGDYHLCESVRFMATPPHDGAFTE 123

Query: 145 YVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMV 204
           YV  PA + Y LPESVS  EGA+CEPLSV +HA RR     G  VL+ GAGPIGL+    
Sbjct: 124 YVSWPADFAYTLPESVSTAEGALCEPLSVGIHACRRGSVGTGDTVLITGAGPIGLMVLEA 183

Query: 205 AKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALD 264
           A+A GA+ I++TD+   +L FAE   GAD  +   D+ E D    V +  DG  AD+ ++
Sbjct: 184 ARAAGATDIILTDVVKEKLEFAEKR-GADLTV---DVTETDLDTAVAEYTDGVGADVVVE 239

Query: 265 CAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVP--LVDASSREIDIFGVFRYSNTYPTC 322
            +G E +++  + VVR GG + LVG+ S A  VP  +++    E+D+ G FRY NTY   
Sbjct: 240 ASGAEPSIKSTIDVVRRGGTVVLVGLASEA-EVPFDVLELIDNEVDVHGSFRYKNTYDAA 298

Query: 323 IALLASGRVNVKPLI 337
           + LLA G V+V+ +I
Sbjct: 299 VDLLADGEVDVEGII 313

gb|AAC24597.1| xylitol dehydrogenase; XDH [Candida sp. HA167]
(353 aa)

Score: 278 bits (710), Expect: 2.11833e-73
Length: 351, Idn/Pos/Gap = 154/218/11 (43%/62%/3%)

Query:  26 VLVRPRELRVMLRSVPAPA-PGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHE  84
           VL +P +++   R +P  + P  V++Q++  GICGSDVHY+ HG+ G F +  PM++GHE
Sbjct:  10 VLQKPFDVKFEDRPIPKLSDPYSVKIQVKKTGICGSDVHYFTHGAIGDFVVKAPMVLGHE  69

Query:  85 SAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLAR 144
           S+GVV  +G+ V SL+VGDRVA+EPGVP       + GRYNLCP++ F ATPP DG+L +
Sbjct:  70 SSGVVLEVGSEVKSLKVGDRVAMEPGVPSRHSDEYKSGRYNLCPHMAFAATPPYDGTLCK 129

Query: 145 YVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMV 204
           Y   P  +C +LPE VSLEEGA+ EPLSVAVH+++      GS V + GAGP+GLL   V
Sbjct: 130 YYILPEDFCVKLPEHVSLEEGALVEPLSVAVHSSKLGNIKPGSHVAIYGAGPVGLLVAAV 189

Query: 205 AKAFGASIIVVTDIDDRRLAFA-ETHAGADAVINTRDLDEHDAALVVQQALDGAQADIAL 263
           A AFGA  + + D+ + RL  A E  A A   ++ +D  +  AA VV  A +G   D+ +
Sbjct: 190 ASAFGAESVTIIDLVESRLNLAKELGATATVQVDFKDTPKESAAKVV-AANNGIAPDVVI 248

Query: 264 DCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYS-NTYPTC 322
           D +G E+++  A++ +RPGG    VGMG   +  P+     +E+ + G FRY    YP  
Sbjct: 249 DASGAEASINSAINAIRPGGTYVQVGMGKPDVSFPIATLIGKELTVKGSFRYGYGDYPLA 308

Query: 323 IALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANG-AVKVMLTIPE 372
           ++LLASG+VNVK LITH      E   E A E  +   +G A+K ++  PE
Sbjct: 309 VSLLASGKVNVKKLITH------EVKFEDAAEAFQLVRDGKAIKCIINGPE 353

dbj|BAC81768.1| xylitol dehydrogenase [Aspergillus oryzae]
(382 aa)

Score: 277 bits (709), Expect: 3.21496e-73
Length: 342, Idn/Pos/Gap = 152/223/15 (44%/65%/4%)

Query:  37 LRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGV  96
           ++S  +  PGEV +Q+R  GICGSDVH+W  G  GP  +    I+GHESAG V A+ + V
Sbjct:  34 VKSGESLKPGEVTVQVRSTGICGSDVHFWHAGCIGPMIVTGDHILGHESAGEVIAVASDV  93

Query:  97 TSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRL 156
           T L+ GDRVA+EP +PC  C+ C  GRYN C  + F +TPPVDG L RYV HPA WC+++
Sbjct:  94 THLKPGDRVAVEPNIPCHACEPCLTGRYNGCEKVLFLSTPPVDGLLRRYVNHPAVWCHKI 153

Query: 157 PESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVT 216
            + +S E+GA+ EPLSV++ A  R+G  +G  VLV GAGPIGL+  + A+A GA+ IV+T
Sbjct: 154 GD-MSYEDGALLEPLSVSLAAIERSGLRLGDPVLVTGAGPIGLITLLSARAAGATPIVIT 212

Query: 217 DIDDRRLAFAETHAGADAV---INTRDLDEHDAALVVQ-------QALDGAQADIALDCA 266
           DID+ RLAFA++    D +   + T    E +AA ++         A D  +  +AL+C 
Sbjct: 213 DIDEGRLAFAKSLV-PDVITYKVQTNLSAEDNAAGIIDAFNDGQGSAPDALKPKLALECT 271

Query: 267 GLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALL 326
           G+ES++  A+  V+ GG++ ++G+G + M +P +  S++EID+   +RY NT+P  I L+
Sbjct: 272 GVESSVASAIWSVKFGGKVFVIGVGKNEMKIPFMRLSTQEIDLQYQYRYCNTWPRAIRLV 331

Query: 327 ASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVML 368
            +G +++K L+THRF  L E +L+ AFETA     GA+KV +
Sbjct: 332 RNGVISLKKLVTHRF--LLEDALK-AFETAADPKTGAIKVQI 370

emb|CAA98826.1| unnamed protein product [Saccharomyces cerevisiae]
sp|Q07786|DHSO2_YEAST Sorbitol dehydrogenase 2 (L-iditol 2-dehydrogenase 2)
ref|NP_010035.1| Protein of unknown function, computational analysis of large-scale protein-protein interaction data suggests a possible role in fructose or mannose metabolism [Saccharomyces cerevisiae]
(357 aa)

Score: 276 bits (706), Expect: 7.40526e-73
Length: 330, Idn/Pos/Gap = 140/204/6 (42%/61%/1%)

Query:  17 LNEKANPCGVLVRPRELRVMLRSVPA-PAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRL  75
           +++ +NP  VL +  ++ +  R +P    P  V+L ++  GICGSD+HY+  G  G + L
Sbjct:   1 MSQNSNPAVVLEKVGDIAIEQRPIPTIKDPHYVKLAIKATGICGSDIHYYRSGGIGKYIL  60

Query:  76 HDPMIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFAT 135
             PM++GHES+G V  +G  VT ++VGDRVA+EPGVP       +EG YNLCP++ F AT
Sbjct:  61 KAPMVLGHESSGQVVEVGDAVTRVKVGDRVAIEPGVPSRYSDETKEGSYNLCPHMAFAAT 120

Query: 136 PPVDGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAG 195
           PP+DG+L +Y   P  +  +LPE VS EEGA  EPLSV VH+N+ AG   G+ V+V GAG
Sbjct: 121 PPIDGTLVKYYLSPEDFLVKLPEGVSYEEGACVEPLSVGVHSNKLAGVRFGTKVVVFGAG 180

Query: 196 PIGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLD---EHDAALVVQQ 252
           P+GLL   VA+AFGA+ ++  D+ D +L  A+   GA    N+         D A  VQ+
Sbjct: 181 PVGLLTGAVARAFGATDVIFVDVFDNKLQRAKDF-GATNTFNSSQFSTDKAQDLADGVQK 239

Query: 253 ALDGAQADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGV 312
            L G  AD+  +C+G +  +  A+   + GG +  VGMG +  + P+ + S +E+ + G 
Sbjct: 240 LLGGNHADVVFECSGADVCIDAAVKTTKVGGTMVQVGMGKNYTNFPIAEVSGKEMKLIGC 299

Query: 313 FRYS-NTYPTCIALLASGRVNVKPLITHRF 341
           FRYS   Y   + L+A+G+VNVKPLITH+F
Sbjct: 300 FRYSFGDYRDAVNLVATGKVNVKPLITHKF 329

gb|EAA55580.1| hypothetical protein MG01231.4 [Magnaporthe grisea 70-15]
ref|XP_363305.1| hypothetical protein MG01231.4 [Magnaporthe grisea 70-15]
(372 aa)

Score: 275 bits (702), Expect: 1.82345e-72
Length: 326, Idn/Pos/Gap = 149/214/9 (45%/65%/2%)

Query:  46 GEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGDRV 105
           G+V + +R  GICGSDVH+W HG  GP  + +  I+GHESAG + A+   VTSL+VGDRV
Sbjct:  49 GQVTIAIRSTGICGSDVHFWHHGCIGPMIVREDHILGHESAGEIIAVHPSVTSLKVGDRV 108

Query: 106 ALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPESVSLEEG 165
           A+EP V C +C+ C  GRYN C  + F +TPPV G L RYV HPA WC+++ + +S E+G
Sbjct: 109 AVEPQVICYECEPCLTGRYNGCEKVDFLSTPPVPGLLRRYVNHPAVWCHKIGD-MSWEDG 167

Query: 166 AMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAF 225
           AM EPLSVA+   +RAG T+G  VLV GAGPIGL+  + AKA GA  +V+TDIDD RL F
Sbjct: 168 AMLEPLSVALAGIQRAGITLGDPVLVCGAGPIGLITLLCAKAAGACPLVITDIDDGRLKF 227

Query: 226 AETHAGADAV---INTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVVRPG 282
           A+     D +   +  R   E DAA  + +A  G +  +A++C G+ES++  A+  V+ G
Sbjct: 228 AKELV-PDVITFKVEGRPTAE-DAAKSIVEAFGGVEPTLAIECTGVESSIASAIWAVKFG 285

Query: 283 GRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASGRVNVKPLITHRFM 342
           G++ ++G+G + + +P + AS RE+D+   +RY NT+P  I L+ +  +++  L+THRF 
Sbjct: 286 GKVFVIGVGRNEISLPFMRASVREVDLQFQYRYCNTWPRAIRLIQNKVIDLTKLVTHRF- 344

Query: 343 GLEESSLEAAFETARTAANGAVKVML 368
            LE++    AFETA     GA+KV +
Sbjct: 345 PLEDAL--KAFETAADPKTGAIKVQI 368

emb|CAG79457.1| unnamed protein product [Yarrowia lipolytica CLIB99]
ref|XP_503864.1| hypothetical protein [Yarrowia lipolytica]
(357 aa)

Score: 275 bits (702), Expect: 2.22772e-72
Length: 359, Idn/Pos/Gap = 152/220/13 (42%/61%/3%)

Query:  21 ANPCGVLVRPRELRVMLRSVPA-PAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPM  79
           +NP  VL +P +L    R  P    P  V++ ++  G+CGSDVHY+ HG  G F +  PM
Sbjct:   3 SNPSFVLRKPLDLVFEDRPDPKIQDPHSVKVAVKKTGVCGSDVHYYLHGGIGDFIVKAPM  62

Query:  80 IIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVD 139
           ++GHESAG V  +G  V  L+VGDRVALEPGVP    Q  +EGRYNLCP + F ATPP D
Sbjct:  63 VLGHESAGEVVEVGPEVKDLKVGDRVALEPGVPSRLSQEYKEGRYNLCPCMVFAATPPYD 122

Query: 140 GSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGL 199
           G+L R+   P  +C +LP+ VSLEEGA+ EPLSVAVH N+ A TT   +V+V GAGP+GL
Sbjct: 123 GTLCRHYIIPEDFCVKLPDHVSLEEGALVEPLSVAVHCNKLAKTTAQDVVIVFGAGPVGL 182

Query: 200 LNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGA-- 257
           L   VA AFG+S IV  D+   +L  A+        + T+    +++A  ++  + GA  
Sbjct: 183 LAVGVANAFGSSTIVCVDLVPEKLELAKKFGATHTFVPTKGDSPNESADKIRALIKGAGL 242

Query: 258 --QADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRY 315
               ++AL+C G E +++ A+ V+   GR+  VGMG   ++ P+     +EI + G FRY
Sbjct: 243 SDSPNVALECTGAEPSIQTAVSVLATSGRLVQVGMGKDDVNFPITKCIVKEITVLGSFRY 302

Query: 316 SN-TYPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANG-AVKVMLTIPE 372
            +  YP  + L+ASG+++VK L+T+RF      + + A +  +TAA G A+K+++  PE
Sbjct: 303 CHGDYPLAVQLVASGKIDVKKLVTNRF------TFKEAEQAYKTAAEGKAIKIIIDGPE 355

ref|XP_325071.1| hypothetical protein [Neurospora crassa]
gb|EAA35571.1| hypothetical protein [Neurospora crassa]
(383 aa)

Score: 273 bits (698), Expect: 5.26134e-72
Length: 322, Idn/Pos/Gap = 146/201/6 (45%/62%/1%)

Query:  20 KANPCGVLVRPRELRVMLRSVPAP---APGEVRLQMRCVGICGSDVHYWWHGSCGPFRLH  76
           K+N   VL +P  L V  +  P P   +P +V + +   GICGSDVHYW HG+ G F + 
Sbjct:   6 KSNLSFVLNKP--LDVCFQDKPVPKINSPHDVLVAVNYTGICGSDVHYWLHGAIGHFVVK  63

Query:  77 DPMIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATP 136
           DPM++GHESAG + A+G  V +L VGDRVALEPG PC +C  C  G YNLCP ++F ATP
Sbjct:  64 DPMVLGHESAGTIVAVGDAVKTLSVGDRVALEPGYPCRRCVHCLSGHYNLCPEMRFAATP 123

Query: 137 PVDGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGP 196
           P DG+L  +   PA +CY+LPE+VSL+EGA+ EPL+VAVH  ++A    G  V+V+GAGP
Sbjct: 124 PYDGTLTGFWTAPADFCYKLPETVSLQEGALIEPLAVAVHITKQAKIQPGQTVVVMGAGP 183

Query: 197 IGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDG 256
           +GLL   VAKA+GAS +V  DI   +L FA++ A     ++ R   E +A  ++  A  G
Sbjct: 184 VGLLCAAVAKAYGASKVVSVDIVPSKLEFAKSFAATHTYLSQRVSPEENARNIIAAADLG 243

Query: 257 AQADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRY- 315
             AD  +D +G E +++ A+HVVR GG     GMG   +  P++    +E+   G FRY 
Sbjct: 244 EGADAVIDASGAEPSIQAALHVVRQGGHYVQGGMGKDNITFPIMALCIKEVTASGSFRYG 303

Query: 316 SNTYPTCIALLASGRVNVKPLI 337
           S  Y   I L+  G+V+VK L+
Sbjct: 304 SGDYRLAIQLVEQGKVDVKKLV 325

gb|AAQ91027.1| LRRGT00071 [Rattus norvegicus]
(810 aa)

Score: 268 bits (685), Expect: 2.13794e-70
Length: 308, Idn/Pos/Gap = 140/194/8 (45%/62%/2%)

Query:  55 VGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCL 114
           VGICGSDVHYW HG  G F +  PM++G+E+ G V  +G  V  L+ GDRVA+EPGVP  
Sbjct:  24 VGICGSDVHYWEHGRIGDFVVKKPMVLGYEATGTVTKVGPMVKHLKPGDRVAIEPGVPRE  83

Query: 115 QCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVA 174
             + C+ GRYNL P+I F ATPP  G+L R+  H A +CY+LP+ V+ EEGA+ EPLSV 
Sbjct:  84 INEFCKIGRYNLTPSIFFCATPPDGGNLCRFYKHSADFCYKLPDGVTFEEGALIEPLSVG 143

Query: 175 VHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADA 234
           ++A  R   ++G+ VLV GAGP+G++  +VAKA GAS +VVTD+    L  A+   GAD 
Sbjct: 144 IYACHRRSVSLGNKVLVCGAGPVGIVTLLVAKAMGASQVVVTDLSASWLTKAK-EVGADF 202

Query: 235 VINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSA 294
            I        + A  V+  L G++ ++ +DC+G E +++  ++    G    +VGMG   
Sbjct: 203 TIQVAKETPQEIASKVESLL-GSKPEVTIDCSGAEPSIQSGIYATHSGRTSVIVGMGPEM 261

Query: 295 MHVPLVDASSREIDIFGVFRYSNTYPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFE 354
           + +PLV A+ RE+DI GVFRY NT+   +++LAS  +NVK L+THRF       LE A E
Sbjct: 262 ISLPLVHAAVREVDIKGVFRYCNTWLMAVSMLASKTLNVKHLVTHRF------PLEKAVE 315

Query: 355 TARTAANG 362
              TA  G
Sbjct: 316 AFETAKKG 323

gb|EAA55525.1| hypothetical protein MG01176.4 [Magnaporthe grisea 70-15]
ref|XP_363250.1| hypothetical protein MG01176.4 [Magnaporthe grisea 70-15]
(353 aa)

Score: 268 bits (684), Expect: 2.48439e-70
Length: 329, Idn/Pos/Gap = 150/205/10 (45%/62%/3%)

Query:  47 EVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGDRVA 106
           +V + +   GICGSDVHYW HGS G F + DPM++GHESAG V  +G+ V +LQVGDRVA
Sbjct:  28 DVLVAVNYTGICGSDVHYWHHGSIGDFVVKDPMVLGHESAGTVVEVGSAVKTLQVGDRVA  87

Query: 107 LEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPESVSLEEGA 166
           LEPG PC +C+ C  GRYNLCP ++F ATPP DG+LA +   PA +CY+LPESVSL+EGA
Sbjct:  88 LEPGYPCRRCRDCLAGRYNLCPEMRFAATPPYDGTLAGFWTAPADFCYKLPESVSLQEGA 147

Query: 167 MCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFA 226
           M EPL+V VH  R+A  + G  V+V+GAGP+GLL   VA+AFGA+ +V  DI + +L  A
Sbjct: 148 MIEPLAVGVHIVRQAKVSPGQSVVVMGAGPVGLLCAAVARAFGATTVVSVDIVESKLEVA 207

Query: 227 ETHAGADAVINTRDLDEHDA-ALVVQQAL-DGAQADIALDCAGLESTMRLAMHVVRPGGR 284
           +  A     ++ R   + +A AL+    L D   AD+ +D  G E +++ ++H VR GG 
Sbjct: 208 KQIAATHTYLSQRISPQDNAKALIAAAGLEDNGGADVVIDATGAEPSIQTSIHAVRVGGS 267

Query: 285 ICLVGMGSSAMHVPLVDASSREIDIFGVFRYS-NTYPTCIALLASGRVNVKPLITHRFMG 343
               GMG   +  P++    +E+   G FRYS   Y   I L+A+G+VN+K LIT     
Sbjct: 268 YVQGGMGKPDITFPILAFCCKEVTASGSFRYSAGDYRLAIDLVANGKVNLKALIT----- 322

Query: 344 LEESSLEAAFETARTAANGAV-KVMLTIP 371
            E    + A E     + G V KV++  P
Sbjct: 323 -ETVPFDKAQEAFTKVSEGQVIKVLIAGP 350

ref|XP_324823.1| hypothetical protein [Neurospora crassa]
gb|EAA36547.1| hypothetical protein [Neurospora crassa]
(363 aa)

Score: 268 bits (684), Expect: 2.79223e-70
Length: 323, Idn/Pos/Gap = 143/206/4 (44%/63%/1%)

Query:  46 GEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGDRV 105
           GEV + +R  GICGSDVH+W HG  GP  +    ++GHESAG V A+   V S++VGDRV
Sbjct:  41 GEVTVAVRSTGICGSDVHFWKHGCIGPMIVECDHVLGHESAGEVIAVHPSVKSIKVGDRV 100

Query: 106 ALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPESVSLEEG 165
           A+EP V C  C+ C  GRYN C  + F +TPPV G L RYV HPA WC+++  ++S E G
Sbjct: 101 AIEPQVICNACEPCLTGRYNGCERVDFLSTPPVPGLLRRYVNHPAVWCHKI-GNMSYENG 159

Query: 166 AMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAF 225
           AM EPLSVA+   +RAG  +G  VL+ GAGPIGL+  + AKA GA  +V+TDID+ RL F
Sbjct: 160 AMLEPLSVALAGLQRAGVRLGDPVLICGAGPIGLITMLCAKAAGACPLVITDIDEGRLKF 219

Query: 226 AETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVVRPGGRI 285
           A+             L   ++A  + ++  G +  +AL+C G+ES++  A+  V+ GG++
Sbjct: 220 AKEICPEVVTHKVERLSAEESAKKIVESFGGIEPAVALECTGVESSIAAAIWAVKFGGKV 279

Query: 286 CLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASGRVNVKPLITHRFMGLE 345
            ++G+G + + +P + AS RE+D+   +RY NT+P  I L+ +G V++  L+THRF  LE
Sbjct: 280 FVIGVGKNEIQIPFMRASVREVDLQFQYRYCNTWPRAIRLVENGLVDLTRLVTHRF-PLE 338

Query: 346 ESSLEAAFETARTAANGAVKVML 368
           ++    AFETA     GA+KV +
Sbjct: 339 DAL--KAFETASDPKTGAIKVQI 359

emb|CAH69383.1| L-arabitol dehydrogenase [Aspergillus niger]
(386 aa)

Score: 267 bits (682), Expect: 4.53026e-70
Length: 342, Idn/Pos/Gap = 149/215/23 (43%/62%/6%)

Query:  45 PGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGDR 104
           PGEV +++R  GICGSDVH+W  G  GP  +    I+GHESAG V A+   VTSL+ GDR
Sbjct:  42 PGEVTIEVRSTGICGSDVHFWHAGCIGPMIVTGDHILGHESAGQVVAVAPDVTSLKPGDR 101

Query: 105 VALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPESVSLEE 164
           VA+EP + C  C+ C  GRYN C N++F +TPPVDG L RYV HPA WC+++ + +S E+
Sbjct: 102 VAVEPNIICNACEPCLTGRYNGCENVQFLSTPPVDGLLRRYVNHPAIWCHKIGD-MSYED 160

Query: 165 GAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLA 224
           GA+ EPLSV++    R+G  +G   LV GAGPIGL+  + A+A GAS IV+TDID+ RL 
Sbjct: 161 GALLEPLSVSLAGIERSGLRLGDPCLVTGAGPIGLITLLSARAAGASPIVITDIDEGRLE 220

Query: 225 FAETHAGADAVINTRDLD-------EHDAALVVQQALDGA-------QADIALDCAGLES 270
           FA++      V + R          E +A  ++    DG        +  IA++C G+ES
Sbjct: 221 FAKS-----LVPDVRTYKVQIGLSAEQNAEGIINVFNDGQGSGPGALRPRIAMECTGVES 275

Query: 271 TMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASGR 330
           ++  A+  V+ GG++ ++G+G + M VP +  S+ EID+   +RY NT+P  I L+ +G 
Sbjct: 276 SVASAIWSVKFGGKVFVIGVGKNEMTVPFMRLSTWEIDLQYQYRYCNTWPRAIRLVRNGV 335

Query: 331 VNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLTIPE 372
           +++K L+THRF+ LE++    AFETA     GA+KV +   E
Sbjct: 336 IDLKKLVTHRFL-LEDAI--KAFETAANPKTGAIKVQIMSSE 374

gb|EAA65971.1| hypothetical protein AN0942.2 [Aspergillus nidulans FGSC A4]
ref|XP_405079.1| hypothetical protein AN0942.2 [Aspergillus nidulans FGSC A4]
(386 aa)

Score: 266 bits (679), Expect: 1.06994e-69
Length: 379, Idn/Pos/Gap = 155/227/29 (40%/59%/7%)

Query:   6 TELEESDAGSVLNEKANPCGVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYW  65
           T LE+ + G   N K +      +P    V  +S  +  PGEV +++R  GICGSDVH+W
Sbjct:   5 TVLEKPNIGVFTNPKHDLWVAESKPTLEEV--KSGESLKPGEVTIEVRSTGICGSDVHFW  62

Query:  66 WHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYN 125
             G  GP  +    I+GHESAG V A+   VTSL+VGDRVA+EP V C  C+ C  GRYN
Sbjct:  63 HAGCIGPMIVTGDHILGHESAGDVIAVAPDVTSLKVGDRVAIEPNVICNACEPCLTGRYN 122

Query: 126 LCPNIKFFATPPVDGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTI 185
            C  + F +TPPVDG L RYV HPA WC+++ + +S E+GA+ EPLSV++ A  R+G  +
Sbjct: 123 GCEKVAFLSTPPVDGLLRRYVNHPAVWCHKIGD-MSYEDGALLEPLSVSLAAVERSGLRL 181

Query: 186 GSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFAE----------------TH 229
           G   L+ GAGPIGL+  + A+A GA+ +V+TDID+ RL FA+                  
Sbjct: 182 GDPCLITGAGPIGLITLLSARAAGATPLVITDIDEGRLKFAKELVPEVRTYKVEIGFSAE 241

Query: 230 AGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVVRPGGRICLVG 289
             A+ +IN  + D   A        D  +  IAL+C G+ES++  A+  V+ GG++ ++G
Sbjct: 242 ETAEGIINAFN-DGQGA------GPDALRPRIALECTGVESSVASAIWSVKFGGKVFVIG 294

Query: 290 MGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASGRVNVKPLITHRFMGLEESSL 349
           +G + M +P +  S++EID+   +RY NT+P  I L+ +G +N++ L+THR+  LE++  
Sbjct: 295 VGKNEMKIPFMRLSTQEIDLQYQYRYCNTWPRAIRLVKNGVINLQKLVTHRY-ALEDAL- 352

Query: 350 EAAFETARTAANGAVKVML 368
             AFETA     GA+KV +
Sbjct: 353 -KAFETAANPKTGAIKVQI 370

emb|CAA97627.1| unnamed protein product [Saccharomyces cerevisiae]
pir||S64902 probable sugar reductase (EC 1.1.1.-) YLR070c - yeast  (Saccharomyces cerevisiae)
ref|NP_013171.1| XYLitol Dehydrogenase; YLR070c [Saccharomyces cerevisiae]
(356 aa)

Score: 265 bits (676), Expect: 2.21114e-69
Length: 351, Idn/Pos/Gap = 144/214/9 (41%/60%/2%)

Query:  26 VLVRPRELRVMLRSVPAPA-PGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHE  84
           VL RP ++ +   S+P  + P EV +Q++  GICGSD+HY+ HG    + +  PM++GHE
Sbjct:  11 VLERPGKITLTNVSIPKISDPNEVIIQIKATGICGSDIHYYTHGRIANYVVESPMVLGHE  70

Query:  85 SAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLAR 144
           S+G+V  +G  V +L+VGDRVALEPG+P       +EGRYNL PN+KF ATPP DG+L +
Sbjct:  71 SSGIVALIGENVKTLKVGDRVALEPGIPDRFSPEMKEGRYNLDPNLKFAATPPFDGTLTK 130

Query: 145 YVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMV 204
           Y      + Y+LP+ VS EEGA+ EPLSVA+HAN+ A    G+  +V GAGPIGLL   V
Sbjct: 131 YYKTMKDFVYKLPDDVSFEEGALIEPLSVAIHANKLAKIKFGARCVVFGAGPIGLLAGKV 190

Query: 205 AKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAAL--VVQQALDGAQADIA 262
           A  FGA+ +V  D+ + +L  A    GA  ++N+ DL  H   +  V+++A+    AD+ 
Sbjct: 191 ASVFGAADVVFVDLLENKLETAR-QFGATHIVNSGDL-PHGVTVDSVIKKAIGKKGADVV 248

Query: 263 LDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRY-SNTYPT 321
            +C+G E  +R  + V + GG I  VGMG   +  P+    ++E+   G FRY    Y  
Sbjct: 249 FECSGAEPCVRAGIEVCKAGGTIVQVGMGQEEIQFPISIIPTKELTFQGCFRYCQGDYSD 308

Query: 322 CIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLTIPE 372
            I L++S ++++KP ITHR+    + ++EA  ET+    N  +K ++  PE
Sbjct: 309 SIELVSSRKLSLKPFITHRYSF--KDAVEAFEETSHHPLNN-IKTIIEGPE 356

gb|EAA08890.2| ENSANGP00000011284 [Anopheles gambiae str. PEST]
ref|XP_313335.2| ENSANGP00000011284 [Anopheles gambiae str. PEST]
(351 aa)

Score: 264 bits (675), Expect: 2.48511e-69
Length: 343, Idn/Pos/Gap = 146/211/12 (42%/61%/3%)

Query:  30 PRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVV  89
           P +LR+  R +P PA  EV +++   GICG+D+H+   G  G  RL  P+++GHESAGVV
Sbjct:   8 PNDLRLDERPIPEPAFNEVVVEVDTCGICGTDIHFLKDGGFGAQRLVKPIVLGHESAGVV  67

Query:  90 EALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHP 149
             +G+ VT L+VGDRVA+EP   C  C  C+ G+YN+C + K   T   DG+ + Y    
Sbjct:  68 RKVGSAVTHLKVGDRVAIEPAAGCRTCDLCKVGKYNICLDGKHCTTQKHDGNCSNYYAQY 127

Query: 150 AAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFG 209
           A  C++LP+ V++EEGA+ EPL+VAV+A RRA   +G  V++ GAGPIGL+  + AKA G
Sbjct: 128 ADCCFKLPDHVTMEEGALLEPLAVAVYAGRRADIRLGQRVIIFGAGPIGLVCLIAAKAMG 187

Query: 210 ASIIVVTDID--DRRLAFAETHAGADAVINTRDLD-EHDAALVVQQALDGAQADIALDCA 266
           A+  V+ D++    RL  A+   G   VI  R  D E D    + + L G  AD  L+C+
Sbjct: 188 ATRTVILDLEHAKHRLEVAKK-LGVTGVIGIRKEDTEEDLVKRIHEIL-GGPADRVLECS 245

Query: 267 GLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALL 326
           G +  MR+A+   R  GRICLVG+G+    +P+VDA SREI+I    RY++ YP  + ++
Sbjct: 246 GSQPGMRVAIKATRNAGRICLVGLGNKDAQLPMVDAISREIEITTAMRYNHDYPAALEIV 305

Query: 327 ASGRVNVKPLITHRFMGLEESSLEAAFETARTAANG-AVKVML 368
           ASG V+VKPL++H F       L+   E  R A+ G  +K+M+
Sbjct: 306 ASGYVDVKPLVSHHF------DLQDVHEAFRVASQGEGIKIMI 342

gb|EAA68385.1| conserved hypothetical protein [Gibberella zeae PH-1]
ref|XP_380831.1| conserved hypothetical protein [Gibberella zeae PH-1]
(375 aa)

Score: 264 bits (675), Expect: 2.67892e-69
Length: 323, Idn/Pos/Gap = 139/205/4 (43%/63%/1%)

Query:  46 GEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGDRV 105
           GEV + +R  GICGSDVH+W  G  GP  +    I+GHESAG V A+   V+ L+VGDRV
Sbjct:  53 GEVSVAIRSTGICGSDVHFWHAGCIGPMIVEGDHILGHESAGEVIAVHPSVSHLKVGDRV 112

Query: 106 ALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPESVSLEEG 165
           A+EP +PC  C+ C  GRYN C  ++F +TPPV G L RY+ HPA WC+++  ++S E G
Sbjct: 113 AIEPNIPCGTCEPCLTGRYNGCETVQFLSTPPVPGMLRRYINHPAVWCHKI-GNMSYENG 171

Query: 166 AMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAF 225
           A+ EPLSVA+   +RA   +G  VL+ GAGPIGL+      A GAS IV+TDI + RLAF
Sbjct: 172 ALLEPLSVALAGMQRAEVRLGDPVLICGAGPIGLITLQCCAAAGASPIVITDISESRLAF 231

Query: 226 AETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVVRPGGRI 285
           A+             L   D+A  + ++  G +  +A++C G+ES++  A+  V+ GG++
Sbjct: 232 AKELCPRVITHKVERLSAEDSAKAIVKSFGGVEPTVAMECTGVESSIAAAVWSVKFGGKV 291

Query: 286 CLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASGRVNVKPLITHRFMGLE 345
            ++G+G + +++P + AS RE+DI   +RY NT+P  I L+ +  V++  L+TH+F  LE
Sbjct: 292 FIIGVGKNEINIPFMRASVREVDIQLQYRYCNTWPRAIRLVENNVVDLSKLVTHKFK-LE 350

Query: 346 ESSLEAAFETARTAANGAVKVML 368
           ++    AFET+     GA+KVM+
Sbjct: 351 DAI--KAFETSADPKTGAIKVMI 371

gb|AAO42466.1| xylitol dehydrogenase [Hypocrea jecorina]
(363 aa)

Score: 264 bits (675), Expect: 2.88783e-69
Length: 348, Idn/Pos/Gap = 147/209/7 (42%/60%/2%)

Query:  26 VLVRPRELRVMLRSVPAPA-PGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHE  84
           VL +P ++    R  P    P +V + +   GICGSDVHYW HG+ G F + DPM++GHE
Sbjct:  17 VLNKPGDVTFEERPKPTITDPNDVLVAVNYTGICGSDVHYWVHGAIGHFVVKDPMVLGHE  76

Query:  85 SAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLAR 144
           SAG V  +G  V SL+ GDRVALEPG PC +C  CR G+YNLCP++ F ATPP  G+L  
Sbjct:  77 SAGTVVEVGPAVKSLKPGDRVALEPGYPCRRCSFCRAGKYNLCPDMVFAATPPYHGTLTG 136

Query: 145 YVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMV 204
               PA +CY+LP+ VSL+EGA+ EPL+VAVH  ++A    G  V+V+GAGP+GLL   V
Sbjct: 137 LWAAPADFCYKLPDGVSLQEGALIEPLAVAVHIVKQARVQPGQSVVVMGAGPVGLLCAAV 196

Query: 205 AKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALD 264
           AKA+GAS IV  DI   +L FA         ++ R   E +A  + + A     AD+ +D
Sbjct: 197 AKAYGASTIVSVDIVQSKLDFARGFCSTHTYVSQRISAEDNAKAIKELAGLPGGADVVID 256

Query: 265 CAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRY-SNTYPTCI 323
            +G E +++ ++HVVR GG     GMG S +  P++    +E+ + G FRY +  Y   +
Sbjct: 257 ASGAEPSIQTSIHVVRMGGTYVQGGMGKSDITFPIMAMCLKEVTVRGSFRYGAGDYELAV 316

Query: 324 ALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLTIP 371
            L+ +GRV+VK LIT     +     E AF+  ++    A+K+++  P
Sbjct: 317 ELVRTGRVDVKKLITGT---VSFKQAEEAFQKVKSGE--AIKILIAGP 359

gb|EAA74287.1| hypothetical protein FG04922.1 [Gibberella zeae PH-1]
ref|XP_385098.1| hypothetical protein FG04922.1 [Gibberella zeae PH-1]
(353 aa)

Score: 264 bits (674), Expect: 3.61752e-69
Length: 348, Idn/Pos/Gap = 147/213/7 (42%/61%/2%)

Query:  26 VLVRPRELRVMLRSVPAPA-PGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHE  84
           VL +P ++    R  P+ A P +V + +   GICGSDVHYW HGS G F + DPM++GHE
Sbjct:   8 VLNKPGDVSFEERPKPSLASPHDVLVAVNYTGICGSDVHYWVHGSIGKFVVEDPMVLGHE  67

Query:  85 SAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLAR 144
           SAG V  +G  V +L+ GDRVALEPG PC +CQ C  G+YNLCP++ F ATPP  G+L  
Sbjct:  68 SAGTVVEVGDKVKTLKAGDRVALEPGYPCRRCQNCLAGKYNLCPDMVFAATPPYHGTLTG 127

Query: 145 YVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMV 204
           +   PA +C++LP++VSL+EGA+ EPL+VAVH  ++A    G  V+V+GAGP+GLL   V
Sbjct: 128 FWSAPADFCFKLPDNVSLQEGALIEPLAVAVHIVKQARVKPGDSVVVMGAGPVGLLCAAV 187

Query: 205 AKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALD 264
           AKA+GAS IV  DI   +L FA+  A      + R   E +A  +   A     AD+ +D
Sbjct: 188 AKAYGASKIVSVDIVQSKLDFAKDFASTHVYASQRIAPEENAKNICDLAGLPDGADVVID 247

Query: 265 CAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRY-SNTYPTCI 323
            +G E +++ ++HV++ GG     GMG + +  P++    +E    G FRY +  YP  +
Sbjct: 248 ASGAEPSIQASIHVLKNGGSYVQGGMGKADITFPIMAFCIKEATASGSFRYGAGDYPLAV 307

Query: 324 ALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLTIP 371
            L+A+G+V+VK LIT     ++    E AF+  +     A+KV++  P
Sbjct: 308 ELVATGKVDVKKLITGI---VDFKQAEEAFKKVKEGE--AIKVLIKGP 350

emb|CAH00402.1| unnamed protein product [Kluyveromyces lactis NRRL Y-1140]
ref|XP_453306.1| unnamed protein product [Kluyveromyces lactis]
(354 aa)

Score: 264 bits (674), Expect: 3.80323e-69
Length: 346, Idn/Pos/Gap = 142/210/11 (41%/60%/3%)

Query:  27 LVRPRELRVMLRSVPAPAPGE---VRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGH  83
           +V  ++  +    +PAP   +   V++ ++  GICGSD+HY+ HGS G F +  PM++GH
Sbjct:   8 VVLQKKGEITFEDIPAPEITDSHYVKIHVKKTGICGSDIHYYTHGSIGEFVVKKPMVLGH  67

Query:  84 ESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLA 143
           ES+GVV  +G  VT +QVGDRVA+EPGVP       + G YNLCP++ F ATPP DG+L 
Sbjct:  68 ESSGVVVEVGKDVTLVQVGDRVAIEPGVPSRYSDETKSGHYNLCPHMAFAATPPYDGTLV 127

Query: 144 RYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCM 203
           +Y   P  +  +LP+ VS EEGA  EPL+V VHANR A T+ G  V+V GAGP+GL+   
Sbjct: 128 KYYLAPEDFLVKLPDHVSFEEGACAEPLAVGVHANRLAETSFGKNVVVFGAGPVGLVTGA 187

Query: 204 VAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIAL 263
           VA AFGAS +V  D+ + +L  ++     + + +T+   E +   V++  L G Q +IA+
Sbjct: 188 VAAAFGASAVVYVDVFENKLERSKDFGATNTINSTKYKSEDELTEVIKSELKGEQPEIAI 247

Query: 264 DCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYS-NTYPTC 322
           DC+G E  +R A+ V++ GG    VGMG   ++ P+    ++E+ + G FRY  N Y   
Sbjct: 248 DCSGAEICIRTAIKVLKAGGSYVQVGMGKDNINFPIAMIGAKELRVLGSFRYYFNDYKIA 307

Query: 323 IALLASGRVNVKPLITHRFMGLEES------SLEAAFETARTAANG 362
           + L++ G+VNVK +ITH F   EE+      +LE   E  +T  +G
Sbjct: 308 VKLISEGKVNVKKMITHTFK-FEEAIDAYNFNLEHGSEVVKTMIDG 352

gb|AAS51002.1| ABR229Cp [Ashbya gossypii ATCC 10895]
ref|NP_983178.1| ABR229Cp [Eremothecium gossypii]
(353 aa)

Score: 263 bits (672), Expect: 5.91842e-69
Length: 306, Idn/Pos/Gap = 140/192/3 (45%/62%/0%)

Query:  38 RSVPA-PAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGV  96
           R VP    P  V++++   GICGSDVHY+ HGS GPF +  PM++GHES+G V  +G+ V
Sbjct:  22 RPVPVIEDPHYVKVKIEKTGICGSDVHYYLHGSIGPFVVRSPMVLGHESSGTVVEVGSDV  81

Query:  97 TSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRL 156
           T +++GDRVA+EPGVP    +  + G YNLC  ++F ATPP DG+L +Y   P  +  +L
Sbjct:  82 TRVRIGDRVAIEPGVPSRYSEETKSGHYNLCREMRFAATPPYDGTLVKYYISPEDFLVKL 141

Query: 157 PESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVT 216
           P+SVSLEEGA+CEPL+VAVHANR AGT   S V+V GAGP+GLL   VAKAFGA+ + + 
Sbjct: 142 PDSVSLEEGALCEPLAVAVHANRLAGTQFPSRVVVFGAGPVGLLTASVAKAFGATTVAIV 201

Query: 217 DIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAM 276
           DI   +L  A    G    +++ D    +A     +A   +  DIA DC+G E  +  A+
Sbjct: 202 DISKHKLCVAPA-LGVTHPVDSSDCSSPEALANKLRAELRSDVDIAFDCSGAEICIAAAV 260

Query: 277 HVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRY-SNTYPTCIALLASGRVNVKP 335
            + RPGG    VG     +  PL +A+ +++ I G FRY +  Y T + LLAS RV+   
Sbjct: 261 LICRPGGTHVQVGSSRDYVSFPLAEATVKQLRILGSFRYAAGDYATAVELLASKRVDAAR 320

Query: 336 LITHRF 341
           L+THRF
Sbjct: 321 LVTHRF 326

ref|XP_510366.1| PREDICTED: hypothetical protein XP_510366 [Pan troglodytes]
(428 aa)

Score: 262 bits (670), Expect: 1.00114e-68
Length: 385, Idn/Pos/Gap = 157/215/52 (40%/55%/13%)

Query:  29 RPRELRVMLRSVPAPAPG---EVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHES  85
           +P   +  L    +  PG   EV L+M  VGICGSDVHYW +G  G F +  PM++GHE+
Sbjct:  42 QPSHAKAPLTKSLSDGPGMAVEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEA 101

Query:  86 AGVVEALGAGVTSLQV----------------------GDRVALEPGVPCLQCQRCREGR 123
           +G VE +G+ V   +                       GDRVA+EPG P    + C+ GR
Sbjct: 102 SGTVEKVGSSVGKQRTRPKSGQTLLPPSDMVPSLFSSPGDRVAIEPGAPRENDEFCKMGR 161

Query: 124 YNLCPNIKFFATPPVDGSLARYVCHPAAWCYRL----------------PESVSLEEGAM 167
           YNL P+I F ATPP DG+L R+  H AA+CY +                P++V+ EEGA+
Sbjct: 162 YNLSPSIFFCATPPDDGNLCRFYKHNAAFCYNIVVNSEDLCVSIDSSGFPDNVTFEEGAL 221

Query: 168 CEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRL---A 224
            EPLSV +HA RR G T+G  VLV GAGPIG++  +VAKA GA+ +VVT      L    
Sbjct: 222 IEPLSVGIHACRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTGKTLSVLLPDC 281

Query: 225 FAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVVRPGGR 284
                 GAD V+        + A  V+  L G + ++ ++C G E++++  ++  R GG 
Sbjct: 282 PKPKEIGADLVLQISKESPQEIARKVEGLL-GCKPEVTMECTGAETSIQAGIYATRSGGT 340

Query: 285 ICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASGRVNVKPLITHRFMGL 344
           + LVG+GS    VPL+ A+ RE+DI GVFRY NT+P  I++LAS  VNVKPL+THRF   
Sbjct: 341 LVLVGLGSEMTTVPLLHAAVREVDIKGVFRYCNTWPVAISMLASKSVNVKPLVTHRF--- 397

Query: 345 EESSLEAAFETARTAANG-AVKVML 368
               LE A E   T   G  +K+M+
Sbjct: 398 ---PLEKALEAFETFKKGLGLKIMI 419

gb|AAP42830.1| alcohol dehydrogenase [Puccinia triticina]
(398 aa)

Score: 260 bits (664), Expect: 5.82216e-68
Length: 347, Idn/Pos/Gap = 141/216/18 (40%/62%/5%)

Query:  31 RELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMII------GHE  84
           ++L ++ + +P   PG+V +++R  GICGSD+H+W H      R+ + M++      GHE
Sbjct:  58 QQLNMVKKPMPEVHPGQVLVRVRATGICGSDIHFWKHS-----RVGEKMVVKHECGAGHE 112

Query:  85 SAGVVEALGAGVTSLQVGDRVALEPGVPCLQ--CQRCREGRYNLCPNIKFFATPPVDGSL 142
           SAG V ALG GVT L+VGDRVA+E G+PC +  C+ CR G+YN CP I F+ T P  G +
Sbjct: 113 SAGEVIALGEGVTDLEVGDRVAIETGIPCSKPTCEMCRTGQYNACPEIMFWFTSPYHGLM 172

Query: 143 ARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNC 202
            RY  HP+ W ++LP +VS EEG++ EPL+VA+    RAG  +G  VL+ GAGPIGL+  
Sbjct: 173 TRYHAHPSCWLHKLPPNVSYEEGSLLEPLAVALAGIERAGVRLGDPVLICGAGPIGLVTL 232

Query: 203 MVAKAFGASIIVVTDIDDRRLAFAETHAGADAVIN-TRDLDEHDAALVVQQALDGAQADI 261
           +   A GA  I +TD+ + RL  A+    + +    +    E D A  +Q A+ G +  +
Sbjct: 233 LACHAAGACPIAITDLSEGRLDCAKRLVPSVSTFKISLGESETDVAGQIQAAM-GCKPRV 291

Query: 262 ALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPT 321
           A++C G ES++  A+  V+ GG++ ++G+G     +P +  +  EID+   FRY+N YP 
Sbjct: 292 AMECTGFESSIATAIFSVKFGGKVFVIGVGKDKQTLPFMHMAENEIDLQFQFRYANQYPK 351

Query: 322 CIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVML 368
            I L+++G ++VKPLITHRF  + E ++E AF TA    +G++KV +
Sbjct: 352 AIRLVSTGLIDVKPLITHRF--VLEKAIE-AFNTAADPKSGSMKVQV 395

gb|AAP57209.1| L-arabinitol 4-dehydrogenase [Hypocrea jecorina]
gb|AAL08944.1| L-arabinitol 4-dehydrogenase [Hypocrea jecorina]
(377 aa)

Score: 258 bits (658), Expect: 2.44541e-67
Length: 328, Idn/Pos/Gap = 141/208/11 (42%/63%/3%)

Query:  45 PGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGDR 104
           PGEV + +R  GICGSDVH+W  G  GP  +    I+GHESAG V A+   V+SLQ+GDR
Sbjct:  53 PGEVTIAVRSTGICGSDVHFWHAGCIGPMIVEGDHILGHESAGEVIAVHPTVSSLQIGDR 112

Query: 105 VALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPESVSLEE 164
           VA+EP + C  C+ C  GRYN C  ++F +TPPV G L RYV HPA WC+++  ++S E 
Sbjct: 113 VAIEPNIICNACEPCLTGRYNGCEKVEFLSTPPVPGLLRRYVNHPAVWCHKI-GNMSWEN 171

Query: 165 GAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLA 224
           GA+ EPLSVA+   +RA   +G  VLV GAGPIGL++ + A A GA  +V+TDI + RLA
Sbjct: 172 GALLEPLSVALAGMQRAKVQLGDPVLVCGAGPIGLVSMLCAAAAGACPLVITDISESRLA 231

Query: 225 FAETHAGADAVINTRDLD----EHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVVR 280
           FA+        + T  ++      + A  +  +  G +  + L+C G+ES++  A+   +
Sbjct: 232 FAKEIC---PRVTTHRIEIGKSAEETAKSIVSSFGGVEPAVTLECTGVESSIAAAIWASK 288

Query: 281 PGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASGRVNVKPLITHR 340
            GG++ ++G+G + + +P + AS RE+DI   +RYSNT+P  I L+ SG +++   +THR
Sbjct: 289 FGGKVFVIGVGKNEISIPFMRASVREVDIQLQYRYSNTWPRAIRLIESGVIDLSKFVTHR 348

Query: 341 FMGLEESSLEAAFETARTAANGAVKVML 368
           F  LE++    AFET+    +GA+KVM+
Sbjct: 349 F-PLEDAV--KAFETSADPKSGAIKVMI 373

gb|EAK81329.1| hypothetical protein UM00418.1 [Ustilago maydis 521]
ref|XP_398033.1| hypothetical protein UM00418.1 [Ustilago maydis 521]
(382 aa)

Score: 255 bits (652), Expect: 1.3303e-66
Length: 349, Idn/Pos/Gap = 131/205/27 (37%/58%/7%)

Query:  31 RELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVE  90
           +EL ++  +  AP PG   + +R  G+CGSDVH+W H   GP+++     +GHES G+V 
Sbjct:  28 KELELIKSTPAAPGPGMALVHVRATGVCGSDVHFWKHAGLGPWKIESQCALGHESGGIVI  87

Query:  91 ALGAGVTSLQVGDRVALEPGVPCLQ--CQRCREGRYNLCPNIKFFATPPVDGSLARYVCH 148
           A+G GV ++  GDRVA+EPGVPC +  C  CR G+YNLCP + F++ PP DG+L RY  H
Sbjct:  88 AVGEGVDNVVPGDRVAIEPGVPCFKATCDFCRTGKYNLCPTVDFYSVPPKDGTLKRYHEH 147

Query: 149 PAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAF 208
           PA W +++P+++S EE A+ EPLSV + A  +A  ++G+ VL+ GAGPIG++  + A A 
Sbjct: 148 PAGWLHKVPDNMSYEEIALLEPLSVTLQATLQAEISLGTPVLITGAGPIGIVQLLCASAA 207

Query: 209 GASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALV----------------VQQ 252
           GA+ IV+TD+   RL FA+          T  +D   + L                 + Q
Sbjct: 208 GATPIVITDVVKDRLDFAQKIVPGTF---TYQIDPKKSPLESATEICKVFSKASGKHIAQ 264

Query: 253 ALDGAQADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGV 312
                Q  I ++C G+ES+++ A +     G + ++G+G++   +P +  S+ EI +  +
Sbjct: 265 GERDVQPAITMECTGIESSIQTASYATAASGLVFVIGVGANLQQIPFMHLSTNEITLKFL 324

Query: 313 FRYSNTYPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAAN 361
           FRY +T+P  I L++SG+++VK ++T RF       LE A E    AA+
Sbjct: 325 FRYRDTWPRAIRLVSSGKIDVKQIVTSRF------PLEKAKEAVEHAAD 367

emb|CAB12434.1| sorbitol dehydrogenase [Bacillus subtilis subsp. subtilis str. 168]
ref|NP_388496.1| sorbitol dehydrogenase [Bacillus subtilis subsp. subtilis str. 168]
pir||A45052 L-iditol 2-dehydrogenase (EC 1.1.1.14) - Bacillus subtilis
sp|Q06004|DHSO_BACSU Sorbitol dehydrogenase (L-iditol 2-dehydrogenase) (Glucitol dehydrogenase)
gb|AAA22508.1| sorbitol dehydrogenase
(353 aa)

Score: 255 bits (651), Expect: 1.66644e-66
Length: 347, Idn/Pos/Gap = 143/216/12 (41%/62%/3%)

Query:  25 GVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHE  84
            V+   RE+++    VP     EV +++  VGICGSD+HY+ +G  G + +  P I+GHE
Sbjct:  12 AVMHNTREIKIETLPVPDINHDEVLIKVMAVGICGSDLHYYTNGRIGNYVVEKPFILGHE  71

Query:  85 SAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLAR 144
            AG + A+G+ V   +VGDRVA+EPGV C +C+ C+EGRYNLCP+++F ATPPVDG+  +
Sbjct:  72 CAGEIAAVGSSVDQFKVGDRVAVEPGVTCGRCEACKEGRYNLCPDVQFLATPPVDGAFVQ 131

Query: 145 YVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMV 204
           Y+     + + +P+S+S EE A+ EP SV +HA  R     GS + ++G GP+GL+    
Sbjct: 132 YIKMRQDFVFLIPDSLSYEEAALIEPFSVGIHAAARTKLQPGSTIAIMGMGPVGLMAVAA 191

Query: 205 AKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALD 264
           AKAFGA  I+VTD++  RL  A+   GA  +IN R   E DA   ++   +    D+A +
Sbjct: 192 AKAFGAGTIIVTDLEPLRLEAAKK-MGATHIINIR---EQDALEEIKTITNDRGVDVAWE 247

Query: 265 CAGLESTMRLAMHVVRPGGRICLVGMGSS---AMHVPLVDASSREIDIFGVFRYSNTYPT 321
            AG  + ++ A+  VR GG++ +VG+ S     ++VP +  +  EIDI+G+FRY+NTYP 
Sbjct: 248 TAGNPAALQSALASVRRGGKLAIVGLPSQNEIPLNVPFI--ADNEIDIYGIFRYANTYPK 305

Query: 322 CIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVML 368
            I  LASG V+ K L+T ++  LE++  + A E A    N  +KVM+
Sbjct: 306 GIEFLASGIVDTKHLVTDQY-SLEQT--QDAMERALQFKNECLKVMV 349

gb|EAL18040.1| hypothetical protein CNBK0610 [Cryptococcus neoformans var. neoformans B-3501A]
(400 aa)

Score: 252 bits (643), Expect: 1.48315e-65
Length: 366, Idn/Pos/Gap = 142/211/9 (38%/57%/2%)

Query:   7 ELEESDAGSVLNEKANPCGVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWW  66
           EL++ D   + + KAN          ++++ + +P     EV + ++  GICGSDVH+W 
Sbjct:  38 ELKQGDK-ELEDPKANLACAYDEKHNVKMINKPIPKARQDEVVVHIKATGICGSDVHFWK  96

Query:  67 HGSCGPFRL-HDPMIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQ--CQRCREGR 123
           HG  GP  +  D    GHESAG V  +G GV   +VGDRVA+E GVPC Q  C  C  GR
Sbjct:  97 HGQIGPTMIVTDTCGAGHESAGEVVEVGPGVEQWKVGDRVAIECGVPCGQASCGPCVTGR 156

Query: 124 YNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGT 183
           YN CP + FF+TPP  G+L RY  HPA+W +RLP+++S EEGA+CEPL+VA+ A  RAG 
Sbjct: 157 YNACPQVVFFSTPPYHGTLTRYHAHPASWLHRLPDNLSYEEGALCEPLAVALAALERAGN 216

Query: 184 TIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINT-RDLD 242
            +G  VL+ GAGPIGL+  + + A G + IV+TD+   RL  A+        +   R   
Sbjct: 217 RLGDPVLICGAGPIGLVTLLASHAAGCTPIVITDLQASRLEVAKKLIPTVKTVQIERSWT 276

Query: 243 EHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDA 302
             + +  +++A  G    +A+D  G ES++  A++ V  GG++ ++G G S    P    
Sbjct: 277 SKETSEAIKEAA-GTGIRVAIDATGFESSITAAIYSVVFGGKVFVIGAGPSEQKYPFGYC 335

Query: 303 SSREIDIFGVFRYSNTYPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANG 362
           S+ EID+   +RY++ YP  + +++ G +N+KPL+TH F     +    AF  A     G
Sbjct: 336 SANEIDLQFQYRYAHQYPKALRIVSGGLINLKPLLTHTF---PLNKAVEAFHVAADPTKG 392

Query: 363 AVKVML 368
           A+KV +
Sbjct: 393 AIKVQI 398

gb|AAW46366.1| L-iditol 2-dehydrogenase, putative [Cryptococcus neoformans var. neoformans JEC21]
ref|XP_567883.1| L-iditol 2-dehydrogenase, putative [Cryptococcus neoformans var. neoformans JEC21]
(400 aa)

Score: 251 bits (642), Expect: 2.10561e-65
Length: 366, Idn/Pos/Gap = 141/210/9 (38%/57%/2%)

Query:   7 ELEESDAGSVLNEKANPCGVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWW  66
           EL++ D   + + KAN          ++++ + +P     EV + ++  GICGSDVH+W 
Sbjct:  38 ELKQGDK-ELEDPKANLACAYDEKHNVKMINKPIPKARQDEVVVHIKATGICGSDVHFWK  96

Query:  67 HGSCGPFRL-HDPMIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQ--CQRCREGR 123
           HG  GP  +  D    GHESAG V  +G GV   +VGDRVA+E GVPC Q  C  C  GR
Sbjct:  97 HGQIGPTMIVTDTCGAGHESAGEVVEVGPGVEQWKVGDRVAIECGVPCGQASCGPCVTGR 156

Query: 124 YNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGT 183
           YN CP + FF+TPP  G+L RY  HPA+W +RLP+++S EEGA+CEP +VA+ A  RAG 
Sbjct: 157 YNACPQVVFFSTPPYHGTLTRYHAHPASWLHRLPDNLSYEEGALCEPFAVALAALERAGN 216

Query: 184 TIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINT-RDLD 242
            +G  VL+ GAGPIGL+  + + A G + IV+TD+   RL  A+        +   R   
Sbjct: 217 RLGDPVLICGAGPIGLVTLLASHAAGCTPIVITDLQASRLEVAKKLIPTVKTVQIERSWT 276

Query: 243 EHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDA 302
             + +  +++A  G    +A+D  G ES++  A++ V  GG++ ++G G S    P    
Sbjct: 277 SKETSEAIKEAA-GTGIRVAIDATGFESSITAAIYSVVFGGKVFVIGAGPSEQKYPFGYC 335

Query: 303 SSREIDIFGVFRYSNTYPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANG 362
           S+ EID+   +RY++ YP  + +++ G +N+KPL+TH F     +    AF  A     G
Sbjct: 336 SANEIDLQFQYRYAHQYPKALRIVSGGLINLKPLLTHTF---PLNKAVEAFHVAADPTKG 392

Query: 363 AVKVML 368
           A+KV +
Sbjct: 393 AIKVQI 398

emb|CAG84975.1| unnamed protein product [Debaryomyces hansenii CBS767]
ref|XP_456993.1| unnamed protein product [Debaryomyces hansenii]
(357 aa)

Score: 249 bits (637), Expect: 7.93481e-65
Length: 347, Idn/Pos/Gap = 134/212/14 (38%/61%/4%)

Query:  31 RELRVMLRSVPAPAP--GEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGV  88
           ++ R+ L+  P   P  G+V + +R  GICGSD+H+W  GS G  ++ D  I+GHE+AG 
Sbjct:  14 KDHRIELKEAPVKPPLKGQVLIHVRATGICGSDIHFWKSGSIGDLKVLDNCILGHEAAGD  73

Query:  89 VEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCH 148
           V  +G GVT++ VGDRVA+EPGVPC  C  C +G YNLC +++F    P  GS+ RY+ H
Sbjct:  74 VVEIGEGVTNVSVGDRVAIEPGVPCGNCFLCSQGDYNLCEDVQFIGVFPYHGSMQRYITH 133

Query: 149 PAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAF 208
            + + YRLP++++  +GA+ EP+SVA H   RA   +G  VL+ GAGPIGL+  ++AKA 
Sbjct: 134 NSRYVYRLPDNMTYSQGALVEPISVAYHGIERANLKLGEGVLIAGAGPIGLVALLLAKAS 193

Query: 209 GASIIVVTDIDDRRLAFAETHAGADAV--INTRDLDEHDAALVVQQALDGAQ----ADIA 262
           G + + +TD+   +L FA+T         +NT+   + +A  V  +++ G Q      + 
Sbjct: 194 GCTPLCITDLSKEKLEFAKTLVPQVRTYKVNTKLSPQENAKEV--RSIFGDQECNFPHVT 251

Query: 263 LDCAGLESTMRLAMHVVRPGGRICLVGMGSSAM-HVPLVDASSREIDIFGVFRYSNTYPT 321
           L+C G+ES++    +V R  G + ++G+G   + + P +  S  EID+  + RY +++PT
Sbjct: 252 LECTGVESSIITCAYVTRRSGTLMVIGVGKDIINNFPFMRLSLAEIDVKFINRYHDSWPT 311

Query: 322 CIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVML 368
            I LL+ G +N   LITHRF    E+++E A   +  A NG++KV++
Sbjct: 312 VIRLLSHGIINADLLITHRFT--LENAIE-ALTLSSDACNGSIKVII 355

ref|NP_929227.1| hypothetical protein plu1960 [Photorhabdus luminescens subsp. laumondii TTO1]
emb|CAE14253.1| unnamed protein product [Photorhabdus luminescens subsp. laumondii TTO1]
(342 aa)

Score: 244 bits (623), Expect: 3.25131e-63
Length: 326, Idn/Pos/Gap = 131/200/13 (40%/61%/3%)

Query:  47 EVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGDRVA 106
           +V +++  VGICGSDVHY+ +G  GPF +  PMI+GHE++GV+ A+G  VT L++GDRV 
Sbjct:  27 DVEIKIHSVGICGSDVHYYQYGRIGPFIVEKPMILGHEASGVITAVGKNVTHLKIGDRVC  86

Query: 107 LEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPESVSLEEGA 166
           +EPG+P LQ  + R G YNL P ++F+ATPP+DG L   V HPAA+ ++LP++VS  EGA
Sbjct:  87 MEPGIPNLQSPQSRAGIYNLDPEVRFWATPPIDGCLRERVIHPAAFTFKLPDNVSFAEGA 146

Query: 167 MCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFA 226
           M EPL++ + A  +A    G + LV+GAG IG++  + A A G S +++ D+ D +L  A
Sbjct: 147 MVEPLAIGMQAATKAEIKPGDIALVIGAGTIGIVTALAALAGGCSDVIICDVFDEKLEIA 206

Query: 227 ETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVVRPGGRIC 286
           + + G   V N++ L E   AL      +G   +I  +C+G +  +      + PGG   
Sbjct: 207 KQYPGLHPV-NSKVLTEKVNALT-----EGNGVNILFECSGAKPVIATISEHIAPGGIAV 260

Query: 287 LVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASGRVNVKPLI--THRFMGL 344
           LVGM        +V A ++EI    +FRY+N YP  I LL+SG++ V PL+  T++F   
Sbjct: 261 LVGMPIDPAPFDVVSAQAKEITFKTIFRYANMYPRTIRLLSSGKLKVTPLLSATYKF--- 317

Query: 345 EESSLEAAFETARTAANGAVKVMLTI 370
            + S++ A+E A       +K+ML +
Sbjct: 318 -KDSVQ-AYERAAEGRPTDIKIMLEM 341

emb|CAG85752.1| unnamed protein product [Debaryomyces hansenii CBS767]
ref|XP_457724.1| unnamed protein product [Debaryomyces hansenii]
(352 aa)

Score: 244 bits (622), Expect: 3.7468e-63
Length: 350, Idn/Pos/Gap = 139/207/14 (39%/59%/4%)

Query:  25 GVLVRPR-ELRVMLRSVPAPA---PGEVRLQMRCVGICGSDVHYWWHGSCGP-FRLHDPM  79
           GV   P+ EL V     P  A     EV + ++C GICGSD+H+  HG  GP   +    
Sbjct:   8 GVFTNPKHELYVTEIDTPQAADLTEDEVLVHVKCTGICGSDIHFQKHGCIGPTMVVEGEH  67

Query:  80 IIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVD 139
           I+GHES+G + A+G  VT+L+ GD+VALEPGVPC  C+ C  G+YN C  + F +TPPV 
Sbjct:  68 ILGHESSGEILAVGNKVTNLKTGDKVALEPGVPCKSCKACLTGKYNGCEKVLFSSTPPVA 127

Query: 140 GSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGL 199
           G L RY+ HPA +C+++  S++ ++GA+ EPLSV     R  G  +G  VLV GAGPIG 
Sbjct: 128 GFLRRYIKHPAQFCHKI-NSLTYQQGALLEPLSVLYCGVRHIGLQLGQSVLVCGAGPIGY 186

Query: 200 LNCMVAKAFGASIIVVTDIDDRRLAFAETH-AGADAVINTRDLDEHDAALVVQQALDGAQ 258
           +    A+  GA  IVVTDI+  +L F +        V+ T  L E+    + + A     
Sbjct: 187 VTAKCAELAGAFPIVVTDIEQSKLDFIKKEIPSVTTVLVTGSLQEN----LKKVASATES 242

Query: 259 ADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNT 318
            D+A+DC G+E ++ LA H +  GG++ ++G+G      P +  S +EI +   +RY+NT
Sbjct: 243 FDVAIDCTGVEPSLELATHALDFGGKLHIIGVGREFQKFPFMILSVKEIHVTFQYRYANT 302

Query: 319 YPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVML 368
           +PT + L+ +G +N+  LITH F  LE++  E AF+ A    +GA+K+++
Sbjct: 303 WPTVVKLMQAGIINLDKLITHSF-ALEDA--EEAFKLAADPKSGAMKIII 349

gb|EAL00550.1| hypothetical protein CaO19.7676 [Candida albicans SC5314]
(360 aa)

Score: 244 bits (622), Expect: 4.00543e-63
Length: 345, Idn/Pos/Gap = 141/203/26 (40%/58%/7%)

Query:  44 APGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGD 103
           +P +V ++++  GICGSD+HY+ HGS GPF L  PM++GHESAGVV A+G  VT+L+VGD
Sbjct:  26 SPRDVIVEVKKTGICGSDIHYYAHGSIGPFVLRKPMVLGHESAGVVVAVGDDVTNLKVGD  85

Query: 104 RVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVD-------GSLARYVCHPAAWCYRL 156
           +VA+EPGVP       + G Y+LCP++ F ATPPV+       G+L +Y   PA + ++L
Sbjct:  86 KVAIEPGVPSRYSDEYKSGNYHLCPHMAFAATPPVNPDEPNPPGTLCKYYKAPADFLFKL 145

Query: 157 PESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVT 216
           P+ VSLE GAM EPL+V VHA + A    G  V+V GAGP+GLL   VAK  GA  I+V 
Sbjct: 146 PDHVSLELGAMVEPLTVGVHACKLANLKFGENVVVFGAGPVGLLTAAVAKTIGAKNIMVV 205

Query: 217 DIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAM 276
           DI D +L  A+    A    N++  D+      + +A DG +  + L+C+G +  +   +
Sbjct: 206 DIFDNKLQMAKDMGAATHTFNSKTGDD------LVKAFDGIEPSVVLECSGAKQCIYTGV 259

Query: 277 HVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYS-NTYPTCIALLASGRVNVKP 335
            +++ GGR   VG     ++ P+ D S+RE+ ++G FRY    Y T I +L    +N K 
Sbjct: 260 KILKAGGRFVQVGNAGGDVNFPIADFSTRELTLYGSFRYGYGDYQTSIDILDKNYINGKE 319

Query: 336 --------LITHRFMGLEESSLEAAFETARTAANGAVKVMLTIPE 372
                   LITHRF   +      A++  R   NGAVK ++  PE
Sbjct: 320 NAPINFELLITHRF---KFKDAIKAYDLVR-GGNGAVKCLIDGPE 360

gb|EAA59731.1| hypothetical protein AN8109.2 [Aspergillus nidulans FGSC A4]
ref|XP_412246.1| hypothetical protein AN8109.2 [Aspergillus nidulans FGSC A4]
(583 aa)

Score: 242 bits (618), Expect: 1.0632e-62
Length: 327, Idn/Pos/Gap = 131/187/12 (40%/57%/3%)

Query:  19 EKANPCGVLVRPRELRVMLRSVPA-PAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHD  77
           ++ NP  VL   +++    R +P    P +VR+Q+   GICGSDVHYW  G  G F L  
Sbjct: 252 KETNPSFVLRAVKDVAFEDRVIPPLKDPWDVRVQVAQTGICGSDVHYWQRGRIGDFILES 311

Query:  78 PMIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPP 137
           P+++GHES+G+V  +G+ V +L+VG +VA+EPGVPC  C  CR G YNLCP+  F ATPP
Sbjct: 312 PIVLGHESSGIVTEIGSAVKNLKVGQKVAIEPGVPCRHCDYCRSGSYNLCPDTVFAATPP 371

Query: 138 VDGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPI 197
            DG+L +Y    A +CY LP  + LEEGAM EP++VAV   +         V+V G GPI
Sbjct: 372 HDGTLQKYYITQADYCYPLPYHMGLEEGAMVEPVAVAVQITKVGNVRPNQTVVVFGCGPI 431

Query: 198 GLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAV---------INTRDLDEHDAAL 248
           GLL   V+KA+    ++  DI   RL FA+   GAD V         +      E  AAL
Sbjct: 432 GLLCQAVSKAYACKKVIGVDISQSRLDFAQAF-GADGVFLPPPRPEGVEETAWSEKVAAL 490

Query: 249 VVQQALDGAQADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREID 308
           + ++   G   D+ L+  G +S ++  +H+V+ GG     GMG   +  P+  A  R++ 
Sbjct: 491 IKEKFGLGEGPDVVLEATGAQSCIQTGVHLVKKGGTYVQAGMGKENVVFPITTACIRDLT 550

Query: 309 IFGVFRYSN-TYPTCIALLASGRVNVK 334
           I G  RYS   YP  + L+ASG+++V+
Sbjct: 551 IRGSIRYSTGCYPVAVDLIASGKIDVR 577

pir||S32484 L-iditol 2-dehydrogenase (EC 1.1.1.14) - silkworm
sp|Q02912|DHSO_BOMMO Sorbitol dehydrogenase (L-iditol 2-dehydrogenase)
dbj|BAA02634.1| mammalian sorbitol dehydrogenase homolog [Bombyx mori]
dbj|BAA11030.1| sorbitol dehydrogenase [Bombyx mori]
(348 aa)

Score: 242 bits (618), Expect: 1.14612e-62
Length: 351, Idn/Pos/Gap = 137/212/10 (39%/60%/2%)

Query:  22 NPCGVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMII  81
           N   VL    ++R+    VP     EV +++ CVGICGSDV  +  G+CG   +  P++I
Sbjct:   4 NYAAVLHGANDVRIEKIPVPEINDDEVLIKIDCVGICGSDVKLYSTGTCGADVIDKPIVI  63

Query:  82 GHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGS 141
           GHE AG V  +G  V+SL+VGDRVA+EP  PC  C+ C+ G+YNLC   ++ ++    G+
Sbjct:  64 GHEGAGTVVKVGDKVSSLRVGDRVAIEPTQPCRSCELCKRGKYNLCVEPRYCSSMGAPGN 123

Query: 142 LARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLN 201
           L RY  H A +C++LP+++++EEGA  +PL++ +HA  RA  T+GS +++LGAGPIG+L 
Sbjct: 124 LCRYYKHVADFCHKLPDNLTMEEGAAVQPLAIVIHACNRAKITLGSKIVILGAGPIGILC 183

Query: 202 CMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRD--LDEHDAALVVQQALDGAQA 259
            M AKA GAS I++TD+   RL  A    GAD V+  R    DE     +V+  L G + 
Sbjct: 184 AMSAKAMGASKIILTDVVQSRLD-AALELGADNVLLVRREYTDEEVVEKIVK--LLGDRP 240

Query: 260 DIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTY 319
           D+++D  G  S  R+A+ V +  G + +VG+    + +PL  A  RE+D+ G FR  NTY
Sbjct: 241 DVSIDACGYGSAQRVALLVTKTAGLVLVVGIADKTVELPLSQALLREVDVVGSFRIMNTY 300

Query: 320 PTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLTI 370
              +A ++SG + +   ITHRF     +  + A + A++ A  A+K+++ +
Sbjct: 301 QPALAAVSSGAIPLDKFITHRF---PLNKTKEALDLAKSGA--AMKILIHV 346

ref|YP_174539.1| sorbitol dehydrogenase [Bacillus clausii KSM-K16]
dbj|BAD63578.1| sorbitol dehydrogenase [Bacillus clausii KSM-K16]
(346 aa)

Score: 242 bits (617), Expect: 1.6002e-62
Length: 333, Idn/Pos/Gap = 128/197/9 (38%/59%/2%)

Query:  38 RSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVT  97
           R+ P P  GEV +QM+ VGICGSD+HY+ HG  G      P ++GHE AGVV  +G  V 
Sbjct:  17 RTKPKPGAGEVLIQMKAVGICGSDLHYYEHGRIGERVAKPPFVLGHECAGVVTKVGPEVA  76

Query:  98 SLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLP 157
            L VGD V +EPG+PC +C  CR G YNLCP + F ++PP DG L  Y+CHPA + Y++P
Sbjct:  77 DLNVGDHVVIEPGLPCGECSSCRVGHYNLCPKVLFLSSPPNDGVLMEYICHPAKFTYKMP 136

Query: 158 ESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTD 217
           E +S E  ++ EPLSV ++  ++     GS ++++G GP+GL   + AK +GAS IVVTD
Sbjct: 137 EGLSFELASLAEPLSVGLYTAQKTSIQPGSNIVIMGMGPVGLCMILAAKWYGASNIVVTD 196

Query: 218 IDDRRLAFAETHAGADAV-INTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAM 276
           I+  RL  A+     D + +N     E D A ++ +A      D+ +D +G E+   +A+
Sbjct: 197 IEPYRLEIAKKIGAMDTIQVN----HEADRAGLLAEADRLGGFDMVIDTSGAEAAFDMAV 252

Query: 277 HVVRPGGRICLVGM-GSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASGRVNVKP 335
           ++++ GG I  +G  G +   +PL+    REI    ++RY +T+   +ALL   +   + 
Sbjct: 253 NLLKRGGTIGGIGFPGGAKSTIPLLKMMQREIVYQPIYRYRHTFKHALALLEKEQEAAQL 312

Query: 336 LITHRFMGLEESSLEAAFETARTAANGAVKVML 368
           L+T  F     S + AAF+ A +  + ++KV++
Sbjct: 313 LLTDFF---PMSQISAAFDYAASNKDKSIKVII 342

ref|ZP_00312171.1| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Clostridium thermocellum ATCC 27405]
(347 aa)

Score: 241 bits (614), Expect: 3.25225e-62
Length: 318, Idn/Pos/Gap = 127/188/7 (39%/59%/2%)

Query:  26 VLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHES  85
           VL    +L  + R +P P  GE++++++ VG+CGSD+H++  G    + L  P+ +GHE 
Sbjct:   9 VLTGKEKLEWVERDIPQPGRGELQIKLKHVGVCGSDLHFYKEGRLANWELDGPLALGHEP  68

Query:  86 AGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATP-PVDGSLAR 144
            G+V A+G GV   ++GD+VALEPGVPC +C+ CR+G YNLC +IKF A P   DG  A 
Sbjct:  69 GGIVSAIGEGVEGFEIGDKVALEPGVPCGECEDCRKGHYNLCKHIKFMAIPHEKDGVFAE 128

Query: 145 YVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMV 204
           Y  H A+ CY+LPE+V   EG + EPLSVA+HA   +   IG   +VLG+G IGL   M 
Sbjct: 129 YCVHSASMCYKLPENVDTMEGGLMEPLSVALHATELSNAKIGETAIVLGSGCIGLCTVMA 188

Query: 205 AKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALD 264
            KA G S I VTD+ D+RL  A    GA  V N++  D  + A    + L G  AD   +
Sbjct: 189 LKARGVSEIYVTDVVDKRLEKA-LEVGATRVFNSQREDIVEFA----KTLPGGGADQVYE 243

Query: 265 CAGLESTMRLAMHVVRPGGRICLVGMG-SSAMHVPLVDASSREIDIFGVFRYSNTYPTCI 323
           CAG   T      +++  G++ LVG+     + + +   ++ E  ++ V+RY N YP  I
Sbjct: 244 CAGSRVTTLQTCKLIKRAGKVTLVGVSPEPVLELDIATLNAMEGTVYSVYRYRNMYPIAI 303

Query: 324 ALLASGRVNVKPLITHRF 341
           A ++SG + +K +++H F
Sbjct: 304 AAVSSGVIPLKKIVSHVF 321

emb|CAG34729.1| xylitol dehydrogenase [Arxula adeninivorans]
(368 aa)

Score: 240 bits (613), Expect: 4.0066e-62
Length: 377, Idn/Pos/Gap = 152/221/17 (40%/58%/4%)

Query:   4 METELEESDAGSVLNEKA----NPCGVLVRPRELRVMLRSVPA-PAPGEVRLQMRCVGIC  58
           M  ++EE     VLN +A    NP  VL +P EL    R VP    P +V++Q++  GIC
Sbjct:   1 MAAQVEEQ----VLNLRAQADHNPSFVLKKPLELGFEERPVPVITDPRDVKIQVKKTGIC  56

Query:  59 GSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQR 118
           GSDVH+W HG  G + +  PM++GHES+GVV  +G+ VTSL+VGDRVA+EPGVP  + + 
Sbjct:  57 GSDVHFWQHGRIGDYVVEKPMVLGHESSGVVVEVGSEVTSLKVGDRVAMEPGVPDRRSKE 116

Query: 119 CREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHAN 178
            + GRY+LCP+++F A PP DG+L +Y   P  +C +LPE+V  EEGA+ EPLSVAVH  
Sbjct: 117 YKMGRYHLCPHVRFAACPPTDGTLCKYYTLPEDFCVKLPENVDFEEGALVEPLSVAVHTA 176

Query: 179 RRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINT 238
           R  G   GS V+V GAGPIG L   V KAFGASII   D+ +++L  A+    +   +  
Sbjct: 177 RLLGIYPGSKVVVFGAGPIGQLCIGVCKAFGASIIGAVDLFEQKLETAKEFGASHTYVPQ 236

Query: 239 RDLDEHDAALVVQQALDGAQA-DIALDCAGLESTMRLAMHVVRPGGRICLVGMG-SSAMH 296
           +     + A  + + L   QA D+ +D +G E ++   + ++  GG    V MG +  + 
Sbjct: 237 KGDSHDETAHKILELLPNKQAPDVVIDASGAEQSINAGIELLERGGTFGQVAMGRTDYIQ 296

Query: 297 VPLVDASSREIDIFGVFRYS-NTYPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFET 355
             +   + +EI   GVFRY+   Y     L+  G++ VK L+THR    E++  E A+E 
Sbjct: 297 FAVSRMAMKEIRFQGVFRYTYGDYELATQLIGDGKIPVKKLVTHR-RPFEKA--EEAYEL 353

Query: 356 ARTAANGAVKVMLTIPE 372
            ++    AVK ++  PE
Sbjct: 354 VKSGV--AVKCIIDGPE 368

ref|ZP_00218145.1| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Burkholderia cepacia R18194]
(345 aa)

Score: 240 bits (612), Expect: 6.23489e-62
Length: 349, Idn/Pos/Gap = 145/211/14 (41%/60%/4%)

Query:  26 VLVRPRELRVMLRSVPAP---APGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIG  82
           VL R REL   LR +  P    PG+VR+++  VG+CGSDVHY+ HG  GPFR+  PM++G
Sbjct:   6 VLERTREL--ALRDIDLPQEVGPGDVRIKVHTVGVCGSDVHYYVHGGIGPFRVDAPMVLG  63

Query:  83 HESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSL 142
           HE++G V   GAGVT L+VGDRV +EPGVP         G YNL P+++F+ATPP+ G L
Sbjct:  64 HEASGTVVETGAGVTHLRVGDRVCMEPGVPRFDSPATLRGLYNLDPDVRFWATPPIHGCL 123

Query: 143 ARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNC 202
             YV HPAA+ YRLP++VS  EGA+ EPLS+ + A ++A    G L +V+GAG IG +  
Sbjct: 124 TPYVVHPAAFTYRLPDTVSFAEGAIVEPLSIGLQAAKKAAMKPGDLAVVIGAGTIGAMTA 183

Query: 203 MVAKAFGASIIVVTDIDDRRLA-FAETHAGADAVINTRDLDEHDAALVVQQALDGAQADI 261
           + A A GA+ +++ D+   +LA FA+  A     + T D+     A VV +A DG  AD+
Sbjct: 184 LAALAGGAARVILADVVPDKLALFADNPA-----VTTVDVRTQPLADVVAEATDGWGADV 238

Query: 262 ALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPT 321
             + +G  +     + ++ PGG   L+GM  + + + +V   ++E  I  VFRY+N +P 
Sbjct: 239 VFEASGSANAYAGLVDLMCPGGCAVLIGMPVAPVPLDVVALQAKEGRIESVFRYANIFPR 298

Query: 322 CIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLTI 370
            +AL+ASG ++VKP I+  F   E      AFE A +     VK+ + +
Sbjct: 299 ALALIASGAIDVKPFISRTFPFSEGVR---AFEEAASGHPRDVKIQIEM 344

emb|CAC47105.1| PUTATIVE ALCOHOL DEHYDROGENASE PROTEIN [Sinorhizobium meliloti]
ref|NP_386632.1| PUTATIVE ALCOHOL DEHYDROGENASE PROTEIN [Sinorhizobium meliloti 1021]
sp|Q92MT4|XYLD_RHIME Putative D-xylulose reductase (Xylitol dehydrogenase) (XDH)
(346 aa)

Score: 240 bits (612), Expect: 6.33981e-62
Length: 348, Idn/Pos/Gap = 139/208/10 (39%/59%/2%)

Query:  27 LVRPRELRVMLRSVPAP---APGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGH  83
           LV  ++ ++ LR +P     +P +V + +R VG+CGSDVHY+ HG  GPF +++PMI+GH
Sbjct:   5 LVLEKKGQLSLRDIPVRRDLSPTDVLIGIRTVGVCGSDVHYYTHGKIGPFVVNEPMILGH  64

Query:  84 ESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLA 143
           E+AGVV  +G+ V  L+ GDRV +EPG+P L  +  + G YN+ P+++F+ATPPV G L 
Sbjct:  65 EAAGVVLEVGSQVRHLKKGDRVCMEPGIPDLSSRSSKLGIYNVDPSVRFWATPPVHGCLT 124

Query: 144 RYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCM 203
             V HPAA+ YRLP+ VS  EGAM EP ++ V A  RAG   G +  V+GAGPIG++  +
Sbjct: 125 PEVVHPAAFTYRLPDHVSFAEGAMVEPFAIGVQAALRAGIRPGDVGAVMGAGPIGMMTAL 184

Query: 204 VAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIAL 263
            A A G S + V D+   +L     + G    I T ++ +   +  +  A  G  AD+  
Sbjct: 185 AALAGGCSKVYVADLAQPKLDVIGAYEG----IETINVRQQAVSEALAGATGGWGADVVF 240

Query: 264 DCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCI 323
           +C+G    +     + RPGG + LVGM    +   +V   ++E+ I  VFRY+N Y   I
Sbjct: 241 ECSGAAPAILALPSLARPGGTVVLVGMPVEPVPFDIVGMQAKELRIETVFRYANVYDRAI 300

Query: 324 ALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLTIP 371
            L+ASG+V++KPLI+   +  +ES   AAF+ A  A    VK+ + +P
Sbjct: 301 ELIASGKVDLKPLISAT-IPFDESI--AAFDRAVEARPTDVKIQIEMP 345

gb|EAK83272.1| hypothetical protein UM02150.1 [Ustilago maydis 521]
ref|XP_399765.1| hypothetical protein UM02150.1 [Ustilago maydis 521]
(387 aa)

Score: 239 bits (610), Expect: 9.86573e-62
Length: 319, Idn/Pos/Gap = 132/190/14 (41%/59%/4%)

Query:  38 RSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVT  97
           R + AP PG+V++ +R  G+C SD HY  HG  G F +  PM++GHES+G+V A+G GVT
Sbjct:  35 RPIVAPKPGQVQVNIRQTGLCASDCHYLHHGRIGDFVVRKPMVLGHESSGIVTAVGEGVT  94

Query:  98 SLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLP 157
           + +VGDRVALEPGVPC  CQ C  G YN C +++F ATPP DG+L  Y    +++ + +P
Sbjct:  95 THKVGDRVALEPGVPCRSCQVCLNGMYNQCAHLEFAATPPYDGTLCTYYNIQSSFAHHVP 154

Query: 158 ESVSLEEGAMCEPLSVAVH-ANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVT 216
           + +SLEE ++ EPLSVAV+ A  R        VLV GAGPIGLLN  V KA+ A  +VV 
Sbjct: 155 DHMSLEEASLMEPLSVAVYSAGMRGQVKAMENVLVFGAGPIGLLNAAVCKAYSAKRVVVV 214

Query: 217 DIDDRRLAFAE----THAGADAVINTRDLDEHDAALVVQQALDGAQADIA--------LD 264
           D+ + +L FA+    T     ++    +     AA   Q  +     D+A        L+
Sbjct: 215 DVVESKLEFAKEWCATSTFKPSLPQEGETKAETAARNAQHLISSLGDDVAAREGFDLVLE 274

Query: 265 CAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRY-SNTYPTCI 323
           C G E  + + +  +RP GR   VGMG S +  P+     +EI++ G FRY + TY T I
Sbjct: 275 CTGAEPCINMGIQALRPQGRFVQVGMGRSEVEFPITRVCVKEINVTGSFRYGAGTYKTSI 334

Query: 324 ALLASGRVNVKPLITHRFM 342
            L+++G ++V  ++THRF+
Sbjct: 335 NLVSTGAIDVTKMVTHRFL 353

gb|EAA76150.1| hypothetical protein FG09599.1 [Gibberella zeae PH-1]
ref|XP_389775.1| hypothetical protein FG09599.1 [Gibberella zeae PH-1]
(428 aa)

Score: 239 bits (609), Expect: 1.38899e-61
Length: 399, Idn/Pos/Gap = 146/214/56 (36%/53%/14%)

Query:  26 VLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHES  85
           VL  PR+LR+  R + APA GE+++ ++  GICGSDV Y+   + G      P+ +GHES
Sbjct:  28 VLHGPRDLRMETRIIEAPAAGELQIAVKATGICGSDVSYYKKFANGDLCACHPLSLGHES  87

Query:  86 AGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFAT----PPVDGS 141
           +G V A+G  V   ++GDRVALE GV C  C  CR+GRYNLC  ++F ++    P   G+
Sbjct:  88 SGEVVAIGPQVNGFKLGDRVALEVGVACGNCGTCRKGRYNLCKKLRFRSSAKTYPHYQGT 147

Query: 142 LARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLN 201
           L   + HPA WC++LP++VS E  A+ EPLSVA+HA  RA    GS  +V+GAG +GLL 
Sbjct: 148 LQERINHPAVWCHKLPDNVSYEAAALLEPLSVAIHAVNRARPEPGSTAIVIGAGTVGLLT 207

Query: 202 CMVAKAFGASIIVVTDIDDRRLAFA-----ETHAGADAV--INTRDLDEH---------- 244
             +A+  G + + +TDID  R+ +A      TH     +  +N+ +              
Sbjct: 208 AAMARQSGCTSVTITDIDAGRVNYAVSQGFATHGFVTPISRLNSSNYSSGISTPATGALT 267

Query: 245 -DAALVVQQALDGAQA------------------------DIALDCAGLESTMRLAMHVV 279
             +        DGA++                        D+  +C G E  M  +++  
Sbjct: 268 PASTFSTASRFDGAKSLAADILASSNSPGSFILEEDEDGVDVTFECTGKEVCMHTSLYTT 327

Query: 280 RPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASGRVN------- 332
           + GG++ +VGMG+    +PL  A  REIDI GVFRYSNTYPT I LL S   N       
Sbjct: 328 KAGGKVIMVGMGTPIQTLPLSVAHLREIDILGVFRYSNTYPTGIRLLCSQAANPSGCGLP 387

Query: 333 -VKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLTI 370
            +  ++THRF GL+++  +AAFE A   ++    ++L I
Sbjct: 388 SLDGMVTHRFKGLDKA--QAAFELATRTSDDEGNLVLKI 424

gb|EAL18315.1| hypothetical protein CNBJ2380 [Cryptococcus neoformans var. neoformans B-3501A]
gb|AAW45971.1| xylitol dehydrogenase, putative [Cryptococcus neoformans var. neoformans JEC21]
ref|XP_567488.1| xylitol dehydrogenase, putative [Cryptococcus neoformans var. neoformans JEC21]
(375 aa)

Score: 238 bits (608), Expect: 1.69694e-61
Length: 342, Idn/Pos/Gap = 132/206/28 (38%/60%/8%)

Query:  38 RSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVT  97
           R +P P   EV++++   G+CGSD+HY+ HG+ G F++ +P+++GHES GV+ A+G+ V 
Sbjct:   9 RDIPEPKADEVQIKVAMTGMCGSDLHYYLHGANGTFKIREPLVLGHESCGVITAVGSNVN  68

Query:  98 S---LQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFAT----PPVDGSLARYVCHPA 150
           S   L+VGDRVA+E GV C  C+ CR GRYNLC N++F ++    P +DG+L   +  PA
Sbjct:  69 SGFNLKVGDRVAMEVGVYCKTCKMCRRGRYNLCANMRFASSAKTYPHLDGTLREVMTWPA 128

Query: 151 AWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGA 210
              Y+LP ++ L   A+ EPLSV +HA RRA  + GS +LV+GAG +GLL C +A+A G 
Sbjct: 129 ELVYKLPPNLELPLAALAEPLSVVLHAYRRAHLSPGSRILVIGAGAVGLLTCALARASGC 188

Query: 211 SIIVVTDIDDRRLAFAETH---------------AGADAV-INTRDLDEHDAALVVQQAL 254
           + +V  DI+  +L FA                  +GA+A+ +  +  D   A+  V Q++
Sbjct: 189 TTVVAVDIEQGKLDFAAQQSWTTNTFCLPKGPRVSGAEALEVAGKQWDALKASDAV-QSV 247

Query: 255 DGAQA--DIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGV 312
           +G +   D   +C G+ES M++A      G ++  VGMG+  + +P   +   E+D+ GV
Sbjct: 248 EGLEDGFDAVFECTGVESCMQMAPMAAAIGTKVLFVGMGTKVLALPCGPSLLSEVDLIGV 307

Query: 313 FRYSNTYPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFE 354
           FRY NTYP  +ALLASG++     +   +  L++++   AFE
Sbjct: 308 FRYCNTYPDALALLASGKLGDVSKMASHYYSLDQAA--EAFE 347

sp|Q59545|XYLD_MORMO D-xylulose reductase (Xylitol dehydrogenase) (XDH)
gb|AAA25324.1| xylitol dehydrogenase
(338 aa)

Score: 236 bits (603), Expect: 6.28895e-61
Length: 308, Idn/Pos/Gap = 125/192/6 (40%/62%/1%)

Query:  47 EVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGDRVA 106
           +V +++  VGICGSDVHY+ HG  GPF + +PM++GHE++GV+ A G  V  L+VGDRV 
Sbjct:  29 DVEIKIHTVGICGSDVHYYQHGRIGPFVVDEPMVLGHEASGVITAAGKNVKHLKVGDRVC  88

Query: 107 LEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPESVSLEEGA 166
           +EPG+P LQ  + R G YNL P ++F+ATPP+DG L   V HPAA+ ++LP++VS  +GA
Sbjct:  89 MEPGIPDLQSPQSRAGIYNLDPAVRFWATPPIDGCLRESVIHPAAFTFKLPDNVSFAQGA 148

Query: 167 MCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFA 226
           M EPL++ + +  +AG   G + LV+GAG IG++    A A G S +++ D+ D +L  A
Sbjct: 149 MVEPLAIGMQSATKAGIKPGDIGLVIGAGTIGIIT-QSALAGGCSDVIICDVFDEKLKVA 207

Query: 227 ETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVVRPGGRIC 286
           E + G  AV N++  D+   A  V++   G   ++  +C+G +  +      + PGG   
Sbjct: 208 EKYQGLHAV-NSK--DQQALADKVRELTGGEGVNVLFECSGAKPVIASISDHIAPGGTAV 264

Query: 287 LVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASGRVNVKPLI--THRFMGL 344
           LVGM      + +V A ++E+    + RY+N YP  I LL+SG++NV PL+  T++F   
Sbjct: 265 LVGMPIDPAPLDIVAAQAKEVTFKTILRYANMYPRTIRLLSSGKLNVAPLLSATYKFKDS 324

Query: 345 EESSLEAA 352
            E+   AA
Sbjct: 325 VEAYERAA 332

emb|CAA52443.1| dehydrogenase [Schizosaccharomyces pombe]
(347 aa)

Score: 236 bits (602), Expect: 8.56353e-61
Length: 332, Idn/Pos/Gap = 140/199/9 (42%/59%/2%)

Query:  47 EVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGDRVA 106
           +V++ ++  GICGSDVHYW  G  G F L  PMI+GHESAGVV  +G GV+SL+ GD VA
Sbjct:  18 QVKVAIKATGICGSDVHYWKEGGIGDFILKKPMILGHESAGVVVEVGKGVSSLKPGDPVA  77

Query: 107 LEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPESVSLEEGA 166
           +EPG  C  C  CR GRYNLCP+++F ATPP DG+L  Y      +C +LP+ +S+EEGA
Sbjct:  78 VEPGCVCRLCDYCRSGRYNLCPHMEFAATPPYDGTLRTYYITTEDFCTKLPKQISVEEGA 137

Query: 167 MCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFA 226
           + EP+SVAVHA  R     GS VLV+G G +GLL   VAKA+GA  IV  D    R+ FA
Sbjct: 138 LFEPMSVAVHAMTRGNLKCGSRVLVMGCGTVGLLMMAVAKAYGAIDIVAVDASPSRVEFA 197

Query: 227 ETHAGAD---AVINTRDLDEHDAALVVQQAL--DGAQADIALDCAGLESTMRLAMHVVRP 281
           + + GA     +    +    D A   +QA+     + D A+D  G+   +  A+  ++ 
Sbjct: 198 QKYVGAKPFTPIAAKENESLPDYAQRYKQAIIEKYGEFDFAVDATGVGICIHTAVLALKR 257

Query: 282 GGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSN-TYPTCIALLASGRVNVKPLITHR 340
           GG     G G   +  P+    + EI++ G FRY++  Y   + L+++G V+VKPLITHR
Sbjct: 258 GGTFVQAGNGKPVIDFPINHIINYEINVLGSFRYAHGCYKQSLFLVSNGLVDVKPLITHR 317

Query: 341 FMGLEESSLEAAFETARTAANGAVKVMLTIPE 372
           F    + +L+ A+ET  +   G +KV++  P+
Sbjct: 318 FAF--KDALK-AYETVASGEEGVLKVIIGGPD 346

emb|CAA21910.1| tms1 [Schizosaccharomyces pombe]
pir||S35981 L-iditol 2-dehydrogenase (EC 1.1.1.14) - fission yeast  (Schizosaccharomyces pombe)
ref|NP_595120.1| putative sorbitol dehydrogenase [Schizosaccharomyces pombe]
sp|P36624|DHSO_SCHPO Putative sorbitol dehydrogenase (L-iditol 2-dehydrogenase) (Protein tms1)
(360 aa)

Score: 236 bits (602), Expect: 8.7806e-61
Length: 332, Idn/Pos/Gap = 140/199/9 (42%/59%/2%)

Query:  47 EVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGDRVA 106
           +V++ ++  GICGSDVHYW  G  G F L  PMI+GHESAGVV  +G GV+SL+ GD VA
Sbjct:  31 QVKVAIKATGICGSDVHYWKEGGIGDFILKKPMILGHESAGVVVEVGKGVSSLKPGDPVA  90

Query: 107 LEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPESVSLEEGA 166
           +EPG  C  C  CR GRYNLCP+++F ATPP DG+L  Y      +C +LP+ +S+EEGA
Sbjct:  91 VEPGCVCRLCDYCRSGRYNLCPHMEFAATPPYDGTLRTYYITTEDFCTKLPKQISVEEGA 150

Query: 167 MCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFA 226
           + EP+SVAVHA  R     GS VLV+G G +GLL   VAKA+GA  IV  D    R+ FA
Sbjct: 151 LFEPMSVAVHAMTRGNLKCGSRVLVMGCGTVGLLMMAVAKAYGAIDIVAVDASPSRVEFA 210

Query: 227 ETHAGAD---AVINTRDLDEHDAALVVQQAL--DGAQADIALDCAGLESTMRLAMHVVRP 281
           + + GA     +    +    D A   +QA+     + D A+D  G+   +  A+  ++ 
Sbjct: 211 QKYVGAKPFTPIAAKENESLPDYAQRYKQAIIEKYGEFDFAVDATGVGICIHTAVLALKR 270

Query: 282 GGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSN-TYPTCIALLASGRVNVKPLITHR 340
           GG     G G   +  P+    + EI++ G FRY++  Y   + L+++G V+VKPLITHR
Sbjct: 271 GGTFVQAGNGKPVIDFPINHIINYEINVLGSFRYAHGCYKQSLFLVSNGLVDVKPLITHR 330

Query: 341 FMGLEESSLEAAFETARTAANGAVKVMLTIPE 372
           F    + +L+ A+ET  +   G +KV++  P+
Sbjct: 331 FAF--KDALK-AYETVASGEEGVLKVIIGGPD 359

emb|CAA39066.1| Xylitol dehydrogenase [Pichia stipitis]
gb|AAD28251.1| xylitol dehydrogenase [Pichia stipitis]
pir||S13529 D-xylulose reductase (EC 1.1.1.9) - yeast (Pichia stipitis)
sp|P22144|XYL2_PICST D-xylulose reductase (Xylitol dehydrogenase) (XDH)
(363 aa)

Score: 236 bits (601), Expect: 9.46535e-61
Length: 369, Idn/Pos/Gap = 139/205/25 (37%/55%/6%)

Query:  21 ANPCGVLVRPRELRVMLRSVPAPA-PGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPM  79
           ANP  VL +  ++       P  + P +V +Q++  GICGSD+H++ HG  G F L  PM
Sbjct:   3 ANPSLVLNKIDDISFETYDAPEISEPTDVLVQVKKTGICGSDIHFYAHGRIGNFVLTKPM  62

Query:  80 IIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVD 139
           ++GHESAG V  +G GVTSL+VGD VA+EPG+P       + G YNLCP++ F ATP   
Sbjct:  63 VLGHESAGTVVQVGKGVTSLKVGDNVAIEPGIPSRFSDEYKSGHYNLCPHMAFAATPNSK 122

Query: 140 -------GSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVL 192
                  G+L +Y   P  +  +LP+ VSLE GA+ EPLSV VHA++      G  V V 
Sbjct: 123 EGEPNPPGTLCKYFKSPEDFLVKLPDHVSLELGALVEPLSVGVHASKLGSVAFGDYVAVF 182

Query: 193 GAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQ 252
           GAGP+GLL   VAK FGA  ++V DI D +L  A+    A    N++     +    + +
Sbjct: 183 GAGPVGLLAAAVAKTFGAKGVIVVDIFDNKLKMAKDIGAATHTFNSKTGGSEE----LIK 238

Query: 253 ALDGAQADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGV 312
           A  G   ++ L+C G E  ++L +  + PGGR   VG  +  +  P+   + +E+ +FG 
Sbjct: 239 AFGGNVPNVVLECTGAEPCIKLGVDAIAPGGRFVQVGNAAGPVSFPITVFAMKELTLFGS 298

Query: 313 FRYS-NTYPTCIALL----ASGR----VNVKPLITHRFMGLEESSLEAAFETARTAANGA 363
           FRY  N Y T + +      +GR    ++ + LITHR+    + ++E A++  R A  GA
Sbjct: 299 FRYGFNDYKTAVGIFDTNYQNGRENAPIDFEQLITHRYKF--KDAIE-AYDLVR-AGKGA 354

Query: 364 VKVMLTIPE 372
           VK ++  PE
Sbjct: 355 VKCLIDGPE 363

emb|CAG88650.1| unnamed protein product [Debaryomyces hansenii CBS767]
ref|XP_460359.1| unnamed protein product [Debaryomyces hansenii]
(353 aa)

Score: 236 bits (601), Expect: 9.86859e-61
Length: 352, Idn/Pos/Gap = 140/209/17 (39%/59%/4%)

Query:  25 GVLVRPRELRVMLRSVPAPAPG-----EVRLQMRCVGICGSDVHYWWHGSCGP-FRLHDP  78
           GV   P+   + +  +  P  G     EV + +R  GICGSDVH+  HG  GP   + D 
Sbjct:   8 GVFTNPKH-DLYVSEIETPDVGDLSEEEVLVHVRSTGICGSDVHFQKHGCIGPTMVVEDE  66

Query:  79 MIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPV 138
            I+GHESAG V A+G  V  L+VGD+VALEPGVPC  C+ C  G+YN C N++F++TPPV
Sbjct:  67 HILGHESAGEVLAVGNKVKILKVGDKVALEPGVPCHTCKPCLTGKYNGCENVEFYSTPPV 126

Query: 139 DGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIG 198
            G L RY+ HPAA+C+++   ++  +GA+ EPLSV     R     +G  VLV GAGPIG
Sbjct: 127 HGFLRRYIKHPAAFCHKI-NLLTYAQGALLEPLSVVFCGIRHINLILGQSVLVFGAGPIG 185

Query: 199 LLNCMVAKAFGASIIVVTDIDDRRLAF--AETHAGADAVINTRDLDEHDAALVVQQALDG 256
                 A+A GA  I+VTDI+  +L F   E  +   A++N   L E + A V    ++ 
Sbjct: 186 FATAKAAEAAGAYPIMVTDIEQSKLDFIKKEIPSAITALVNG-SLKE-NVAKVTDDGIN- 242

Query: 257 AQADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYS 316
              D+A++C G+E ++ LA H +  G ++ ++G+G      P +  S +EI+I   +RY+
Sbjct: 243 -NFDVAIECTGVEQSLELATHALDFGAKLHIIGVGKDHQKFPFMLLSVKEINITFQYRYA 301

Query: 317 NTYPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVML 368
           NT+PT I L+ +G + +  L+THRF  LE++    AF+ A    +GA+K+++
Sbjct: 302 NTWPTIIKLVEAGIIKLDNLVTHRFK-LEDAV--DAFKLAGNPKSGAMKILI 350

emb|CAG84916.1| unnamed protein product [Debaryomyces hansenii CBS767]
ref|XP_456938.1| unnamed protein product [Debaryomyces hansenii]
(363 aa)

Score: 235 bits (600), Expect: 1.23621e-60
Length: 368, Idn/Pos/Gap = 132/208/25 (35%/56%/6%)

Query:  22 NPCGVLVRPRELRVMLRSVPA-PAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMI  80
           NP  VL +  ++       P    P +V ++++  GICGSD+HY+ HG+ G F L  PM+
Sbjct:   4 NPSLVLNKINDISFEKYDAPEITEPNDVIVEVKKTGICGSDIHYYTHGAIGGFILKSPMV  63

Query:  81 IGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVD- 139
           +GHES+G+V A+G GVTSL+VGD+VA+EPGVP       + G YNLCP++ F ATP  + 
Sbjct:  64 LGHESSGIVSAVGKGVTSLKVGDKVAIEPGVPSRHSDAYKGGHYNLCPHMVFAATPNSED 123

Query: 140 ------GSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLG 193
                 G+L +Y   P  +  +LP+ VSLE GA+ EPL+V VHA +      G +V+V G
Sbjct: 124 GGVNPPGTLCKYYKSPEDFLVKLPDHVSLELGALVEPLTVGVHAAKLGSIKFGDVVVVFG 183

Query: 194 AGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQA 253
           AGP+GLL   VA  FGA+ ++V D+ + +L  A+    A    N +     D    +  A
Sbjct: 184 AGPVGLLAAAVATKFGATKVMVVDVFESKLEMAKQIGVATHTFNPKLGSNKD----LVAA 239

Query: 254 LDGAQADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVF 313
            D  +  + ++C+G E  ++ A+ ++R GGR   +G  +  +  P+ + +++E+ +FG F
Sbjct: 240 FDNTEPSVVMECSGAEPCIKSAVDILRVGGRYIQIGNSAKPVSFPMTEFATKELTLFGSF 299

Query: 314 RYS-NTYPTCIALL--------ASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAV 364
           RY  N Y T +A+L         +  ++ + LITHRF   +      A++  +   NG V
Sbjct: 300 RYGFNDYKTSVAILDENYRNGKENAAIDFESLITHRF---KFDDAIDAYDLVK-GGNGCV 355

Query: 365 KVMLTIPE 372
           K +++ PE
Sbjct: 356 KCIISGPE 363

ref|ZP_00268260.1| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Rhodospirillum rubrum]
(323 aa)

Score: 235 bits (600), Expect: 1.51029e-60
Length: 300, Idn/Pos/Gap = 125/178/4 (41%/59%/1%)

Query:  42 APAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQV 101
           AP   EVR+ ++ VGICGSDVHY+ HG  G F + +PMI+GHE++GVVE +G+ VT L+V
Sbjct:   2 APGANEVRIAIKSVGICGSDVHYFKHGRIGDFIVTEPMILGHEASGVVEEIGSAVTHLRV  61

Query: 102 GDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPESVS 161
           GDRV +EPGVP         G YNL P+++F+ATPP  G L   V HPA+  YRLP+SVS
Sbjct:  62 GDRVCMEPGVPDFSSIETLRGMYNLDPSVRFWATPPYHGCLTAEVVHPASLTYRLPDSVS 121

Query: 162 LEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDR 221
             EGAM EPL++ V+A  +A    G + +V GAG IG++    A A G + ++V+D+   
Sbjct: 122 FAEGAMVEPLAIGVYAAAKAQIRPGDIAVVTGAGTIGMMVVFAALAAGCAEVIVSDVAAE 181

Query: 222 RLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVVRP 281
           +LA   +H      + T DL     A  V    DG   D+  + +G        + ++  
Sbjct: 182 KLALLASHPE----VTTVDLTRESLADAVAARTDGRGVDVFFEASGSTRPYETMIDLIGR 237

Query: 282 GGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASGRVNVKPLITHRF 341
           GGRI LVGM      + +V    +EI + G FRY+N +   + LL SG++++KPLI+  F
Sbjct: 238 GGRIVLVGMPQEKPQLDVVALQVKEISLTGTFRYANVWDRTLKLLGSGKIDLKPLISATF 297

gb|EAL23452.1| hypothetical protein CNBA1020 [Cryptococcus neoformans var. neoformans B-3501A]
gb|AAW40720.1| sorbitol dehydrogenase, putative [Cryptococcus neoformans var. neoformans JEC21]
ref|XP_566539.1| sorbitol dehydrogenase, putative [Cryptococcus neoformans var. neoformans JEC21]
(379 aa)

Score: 235 bits (599), Expect: 1.74046e-60
Length: 393, Idn/Pos/Gap = 154/215/38 (39%/54%/9%)

Query:   4 METELEESDAGSVLNEKANPCGVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVH  63
           M TEL   +   VL+      GV     ++R   R +P     +V +++   GICGSDVH
Sbjct:   1 MSTELNPDNTSFVLH------GV----EDVRFDQRPIPEVHNDQVLIKVVKTGICGSDVH  50

Query:  64 YWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTS---LQVGDRVALEPGVPCLQCQRCR 120
           Y  HG  G F L +PM +GHESAGVV  LG  V     ++VG RVA+EPGV C  C  C+
Sbjct:  51 YLQHGRIGSFVLEEPMCLGHESAGVVVKLGPNVREDLGVEVGTRVAMEPGVCCRSCANCK 110

Query: 121 EGRYNLCPNIKFFATPP-VDGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHA-N 178
            G Y LCP + F ATPP + G+L RY   PA   + LPESVS E+GAM EPLSV VH+  
Sbjct: 111 AGLYELCPYMSFAATPPTIFGTLCRYYVLPADLVHPLPESVSFEDGAMMEPLSVGVHSVA 170

Query: 179 RRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINT 238
              G      V+V GAGP+GLL   VAKA GA  I+  DI+  RL FA+++A  D  I  
Sbjct: 171 TLGGCKSDQTVIVFGAGPVGLLCMAVAKALGARRIIAVDINKERLEFAKSYAATDVCIPG 230

Query: 239 RDLDEHDA-------------ALVVQQALDGAQADIALDCAGLESTMRLAMHVVRPGGRI 285
             LD  D               L + +   GA  D+A++ +G  + +++ + V++P G  
Sbjct: 231 SKLDGEDGEAYTARIAGELRQELGIPERGKGA-IDLAIEASGAPTCVQIGLAVLKPAGTY 289

Query: 286 CLVGMGSS-AMHVPLVDASSREIDIFGVFRY-SNTYPTCIALLASGRVNVKPLITHRFMG 343
             VGMG+   + VPL    S+++ + G FRY S  YP  I+L+  G +++KPL+T RF  
Sbjct: 290 VQVGMGAKMTVPVPLFHIISKQLHVVGSFRYGSGDYPLAISLVERGLIDLKPLVTQRF-- 347

Query: 344 LEESSLEAAFETARTAAN----GAVKVMLTIPE 372
            +  + + AFET +   +    G +K ++  PE
Sbjct: 348 -KFENAKEAFETTKVGKDKNGKGVIKCIIDGPE 379

gb|EAA70822.1| hypothetical protein FG08942.1 [Gibberella zeae PH-1]
ref|XP_389118.1| hypothetical protein FG08942.1 [Gibberella zeae PH-1]
(380 aa)

Score: 234 bits (598), Expect: 2.43001e-60
Length: 352, Idn/Pos/Gap = 143/216/23 (40%/61%/6%)

Query:  26 VLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHES  85
           VL   ++LR+  R +P P+  EV++ ++  G+CGSD+HY+ H   G   + +P+ +GHES
Sbjct:  10 VLHGEKDLRLEERELPKPSSNEVQVAVQSTGLCGSDLHYYNHFRNGDIIVREPLTLGHES  69

Query:  86 AGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFF----ATPPVDGS 141
           AG V A+G+ VT L+ GD VALE G+PC  C+ C EGRYN+C  +KF     A P   G+
Sbjct:  70 AGTVVAVGSEVTHLKPGDHVALEVGLPCETCELCDEGRYNICRGMKFRSSAKANPHAQGT 129

Query: 142 LARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLN 201
           L   + HPA WC+++PE V+L+ GA+ EPLSVA+HA  RA    GS VLVLGAG +GLL 
Sbjct: 130 LQERINHPAKWCHKMPEHVTLDLGALVEPLSVAMHARDRASLPKGSTVLVLGAGAVGLLA 189

Query: 202 CMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVI-----------NTRDLDEHDAALVV 250
             VAKA  A  +++ DI   RL FA ++  ADA +           +     +  AA+V 
Sbjct: 190 AAVAKADQAKTVIIADILKDRLDFATSNGFADASVVVPMERPQTIEDKLAFAQKVAAMVK 249

Query: 251 QQALDG---AQADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREI 307
           +  +DG    +     +C G+E+ ++ A++  +PGG++ ++GMG+  + +P+  A+ RE+
Sbjct: 250 ETQIDGEAIGEVTAVYECTGVETCVQTAIYATKPGGKVMIIGMGTPVLTIPMSAAALREV 309

Query: 308 DIFGVFRYSNTYPTCIALLASGRVN---VKPLITHRFMGLEESSLEAAFETA 356
           DI GVFRY+NTY   I LL++   N   V  L+T R+ G+++  +E AF+ A
Sbjct: 310 DIVGVFRYANTYKEIIELLSNPPANMPDVSRLVTQRYSGMDK--IEEAFKMA 359

ref|ZP_00342324.1| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Azotobacter vinelandii]
(347 aa)

Score: 234 bits (597), Expect: 3.1737e-60
Length: 349, Idn/Pos/Gap = 141/212/15 (40%/60%/4%)

Query:  26 VLVRPRELRVMLRSVPAP--APGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGH  83
           VL +  +L++    +P P   P +VR+++  VG+CGSDVHY+ HG  G F +  P+++GH
Sbjct:   5 VLEKQHDLKIRDIDLPTPPVGPDDVRIRIHTVGVCGSDVHYYTHGRIGHFIVDRPLVLGH  64

Query:  84 ESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLA 143
           E+AG V  +G+GVT L VGDRV +EPG+P  + +  R G YN+ P++ F+ATPPV G L 
Sbjct:  65 EAAGTVVEVGSGVTRLAVGDRVCMEPGIPDPKSKASRLGLYNVDPSVVFWATPPVHGCLT 124

Query: 144 RYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCM 203
             V HPAA+ Y+LP++V   EGA+ EP ++ + A  +A    G + +V+GAG IG++  +
Sbjct: 125 PEVVHPAAFVYKLPDNVGFAEGALVEPFAIGMQAAVKARIKPGDVAVVIGAGTIGMMTAL 184

Query: 204 VAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIAL 263
            A A GAS ++V+D+   +LA A+ + G  AV N R+    DA   V +  DG  AD+  
Sbjct: 185 AALAGGASRVLVSDLMVEKLAIAQRYEGITAV-NVRERSLRDA---VAEVTDGWGADVVF 240

Query: 264 DCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCI 323
           + +G       A+  V PGG + LVGM    +   +V A ++EI I  VFRY+N Y   +
Sbjct: 241 EASGSARAYGDALAAVCPGGALVLVGMPVEPVPFDVVAAQAKEIRIETVFRYANVYERAV 300

Query: 324 ALLASGRVNVKPLITHRF---MGLEESSLEAAFETARTAANGAVKVMLT 369
            L+ASG+V++KPL++  +    G+E      AFE A +A  G VKV +T
Sbjct: 301 NLIASGKVDLKPLVSATYPFERGVE------AFERAASARPGDVKVQIT 343

gb|EAA63068.1| hypothetical protein AN2666.2 [Aspergillus nidulans FGSC A4]
ref|XP_406803.1| hypothetical protein AN2666.2 [Aspergillus nidulans FGSC A4]
(373 aa)

Score: 234 bits (597), Expect: 3.25414e-60
Length: 336, Idn/Pos/Gap = 143/192/8 (42%/57%/2%)

Query:  38 RSVPA-PAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGV  96
           R +P   A  +V +++   G+CGSDVHYW HG  G + + DP+++GHES+G+V   G+  
Sbjct:  32 RDIPTLQAERDVLVRVVATGLCGSDVHYWQHGRIGRYVVEDPIVLGHESSGIVVQCGSQ-  90

Query:  97 TSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRL 156
           + L VGDRV LEPG+ C  C  CR GRYNLC  ++F ATPP +G+LA Y   PA  CY+L
Sbjct:  91 SGLTVGDRVVLEPGIACNTCHFCRAGRYNLCREMRFAATPPYNGTLATYYRVPAECCYKL 150

Query: 157 PESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVT 216
           P  VSL +GA+ EPLSVAVH+ R AG      V+V GAGP+GLL   VA+AFGAS +VV 
Sbjct: 151 PSHVSLRDGALIEPLSVAVHSCRLAGDMQEKSVVVFGAGPVGLLCAGVARAFGASTVVVV 210

Query: 217 DIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAM 276
           D+   RL  A  +        T +  E +A  ++  A  G  ADI LD  G E  M   +
Sbjct: 211 DVVMSRLQSAVKYGATHTHQATSESAEENAIAILGTAGLGLGADIVLDATGAEPCMNSGI 270

Query: 277 HVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYS-NTYPTCIALLASGRVNVKP 335
           H + PGG    VG+G     +P+     +EI   G FRY    Y T I L++S R+ ++ 
Sbjct: 271 HALAPGGTFVQVGLGRPNPSLPVGQICDKEIVFKGSFRYGPGDYKTAIGLVSSHRIRLEG 330

Query: 336 LITHRFMGLEESSLEAAFETARTAANGAVKVMLTIP 371
           L+TH F     S  E AF     A+   VK ++  P
Sbjct: 331 LVTHEF---SFSQAEEAFHN--VASRAGVKSVIYGP 361

gb|EAA76186.1| hypothetical protein FG06991.1 [Gibberella zeae PH-1]
ref|XP_387167.1| hypothetical protein FG06991.1 [Gibberella zeae PH-1]
(396 aa)

Score: 232 bits (591), Expect: 1.36679e-59
Length: 355, Idn/Pos/Gap = 142/204/14 (40%/57%/3%)

Query:  22 NPCGVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMII  81
           NP   +     L+ +   V AP  GEV L ++  GICGSDVH+W  G  G        II
Sbjct:  39 NPSLQVTADHNLKRVDAPVYAPQAGEVLLHIKATGICGSDVHFWKTGRIGSLVFEGDCII  98

Query:  82 GHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGS 141
           GHE+AGVV  +G  V + + GDRVA+EPGVPC  C  C++GRYNLC +++F    P  G+
Sbjct:  99 GHEAAGVVIQVGEDVDNFKPGDRVAVEPGVPCGHCFLCKDGRYNLCEDVQFSGVYPYAGT 158

Query: 142 LARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLN 201
           L RY  HP+ W ++LP++VS  EGA+ EPLSV +H    A  T+G+ V++ GAGPIGLL 
Sbjct: 159 LQRYKVHPSKWLHKLPDNVSFAEGALLEPLSVVLHGINSAPITLGTPVVICGAGPIGLLA 218

Query: 202 CMVAKAFGASIIVVTDIDDRRLAFAETHAGADAV--INTRDLDEHDAALVVQ--QALDGA 257
              A+A GA  +V+TD++ +RLAFA+          ++T   +E +   V +     +  
Sbjct: 219 LASARASGAHPLVITDVEPKRLAFAKEMVPTVKTYQVDTTKSNEENGKNVRRLFGETEYV 278

Query: 258 QADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAM-HVPLVDASSREIDIFGVFRYS 316
           Q  +  +C G+ES++  A  +VR GG + +VG+G S M ++P +  S  EI I  + RY 
Sbjct: 279 QPRVVFECTGIESSVCSAAFMVRRGGVLMVVGVGRSIMNNLPFMHLSLAEIQIRFINRYK 338

Query: 317 NTYPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAA---NGAVKVML 368
           +T+P  IA L  G V+ K L+TH F       LE A E    ++   NG +KV +
Sbjct: 339 DTWPAGIACLEGGLVDAKKLVTHVF------PLEQALEGLTLSSDPKNGCIKVQI 387

ref|YP_111243.1| putative zinc-binding xylitol/sorbitol dehydrogenase [Burkholderia pseudomallei K96243]
emb|CAH38702.1| putative zinc-binding xylitol/sorbitol dehydrogenase [Burkholderia pseudomallei K96243]
(344 aa)

Score: 231 bits (588), Expect: 3.22804e-59
Length: 348, Idn/Pos/Gap = 137/205/12 (39%/58%/3%)

Query:  26 VLVRPRELRVMLRSVPAP---APGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIG  82
           VL + REL   LR +  P    P +V++++  VG+CGSDVHY+ HG  GPFR+  PM++G
Sbjct:   5 VLEKAREL--ALRDIDLPLEVGPADVKIRVHTVGVCGSDVHYYMHGGIGPFRVDAPMVLG  62

Query:  83 HESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSL 142
           HE++G V  +G  VT L+VG+RV +EPGVP    +    G YNL P+++F+ATPPV G L
Sbjct:  63 HEASGTVVEVGRDVTYLRVGERVCMEPGVPRFDSKATLHGLYNLDPSVRFWATPPVHGCL 122

Query: 143 ARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNC 202
           A YV HPAA+ YRLP +VS  EGA+ EPL++ + A ++A    G + +V+GAG IG +  
Sbjct: 123 APYVVHPAAFTYRLPPNVSFAEGAIVEPLAIGLQAAKKAAMKPGDIAVVVGAGTIGAMTA 182

Query: 203 MVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIA 262
           + A A GA+ +++ D+   +LA       A+  + T D      A  V  A DG  AD+ 
Sbjct: 183 LAALAGGAARVILADVVKEKLAL----FAANRAVTTVDASTQSLADAVAHATDGWGADVV 238

Query: 263 LDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTC 322
            + +G  S     + ++ P G + LVGM  + + + +V   ++E  I  VFRY+N +P  
Sbjct: 239 FEASGNASAYAGIVDLLCPNGCLVLVGMPLAPVPLDVVSLQAKEARIESVFRYANVFPRA 298

Query: 323 IALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLTI 370
           +AL+ASG ++VKP I+  F     S    AFE A +     VK+ + +
Sbjct: 299 LALIASGAIDVKPFISRTF---PFSDGLRAFEAAASGQPHDVKIQIEM 343

ref|YP_105739.1| oxidoreductase, zinc-binding dehydrogenase family [Burkholderia mallei ATCC 23344]
gb|AAU46223.1| oxidoreductase, zinc-binding dehydrogenase family [Burkholderia mallei ATCC 23344]
(344 aa)

Score: 229 bits (585), Expect: 6.67107e-59
Length: 348, Idn/Pos/Gap = 136/205/12 (39%/58%/3%)

Query:  26 VLVRPRELRVMLRSVPAP---APGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIG  82
           VL + REL   LR +  P    P +V++++  VG+CGSDVHY+ HG  GPFR+  PM++G
Sbjct:   5 VLEKAREL--ALRDIDLPLEVGPADVKIRVHTVGVCGSDVHYYMHGGIGPFRVDAPMVLG  62

Query:  83 HESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSL 142
           HE++G V  +G  VT L+VG+RV +EPGVP    +    G YNL P+++F+ATPPV G L
Sbjct:  63 HEASGTVVEVGRDVTYLRVGERVCMEPGVPRFDSKATLHGLYNLDPSVRFWATPPVHGCL 122

Query: 143 ARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNC 202
           A YV HPAA+ YRLP +VS  EGA+ EPL++ + A ++A    G + +V+GAG IG +  
Sbjct: 123 APYVVHPAAFTYRLPPNVSFAEGAIVEPLAIGLQAAKKAAMKPGDIAVVVGAGTIGAMTA 182

Query: 203 MVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIA 262
           + A A GA+ +++ D+   +LA       A+  + T D      A  V  A DG  AD+ 
Sbjct: 183 LAALAGGAARVILADVVKEKLAL----FAANRAVTTVDASTQSLADAVAHATDGWGADVV 238

Query: 263 LDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTC 322
            + +G  +     + ++ P G + LVGM  + + + +V   ++E  I  VFRY+N +P  
Sbjct: 239 FEASGNANAYAGIVDLLCPNGCLVLVGMPLAPVPLDVVSLQAKEARIESVFRYANVFPRA 298

Query: 323 IALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLTI 370
           +AL+ASG ++VKP I+  F     S    AFE A +     VK+ + +
Sbjct: 299 LALIASGAIDVKPFISRTF---PFSDGLRAFEAAASGQPHDVKIQIEM 343

ref|NP_105675.1| xylitol (sorbitol) dehydrogenase [Mesorhizobium loti MAFF303099]
sp|Q98D10|XYLD_RHILO Putative D-xylulose reductase (Xylitol dehydrogenase) (XDH)
dbj|BAB51461.1| xylitol (sorbitol) dehydrogenase [Mesorhizobium loti MAFF303099]
(348 aa)

Score: 229 bits (585), Expect: 6.78333e-59
Length: 315, Idn/Pos/Gap = 125/187/7 (39%/59%/2%)

Query:  27 LVRPRELRVMLRSVPAP---APGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGH  83
           LV  ++  + LR +  P    P +V++ +  VG+CGSDVHY+ HG+ G + +  PM++GH
Sbjct:   4 LVLEKKGELSLREIALPLDVGPDDVKIAIHTVGVCGSDVHYYTHGAIGSYVVRAPMVLGH  63

Query:  84 ESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLA 143
           E+AG V   GA V + + GDRV +EPGVP L  +  + G YN+ P++ F+ATPPV G LA
Sbjct:  64 EAAGTVVETGANVETFKAGDRVCMEPGVPNLSSRATKLGIYNVDPDVSFWATPPVHGVLA 123

Query: 144 RYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCM 203
            Y  HPAA+ Y+LP++VS  EGAM EP ++ + A  RA    G + +V+G GPIG++  +
Sbjct: 124 PYAVHPAAFTYKLPDNVSFAEGAMVEPFAIGMQAASRARIVPGDVAVVVGCGPIGIMIAL 183

Query: 204 VAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIAL 263
            A A G S ++++D    +L  A  +AG   V    ++ E      V  A D   ADI  
Sbjct: 184 AALAGGCSKVLISDFSAPKLKIAAQYAGIVPV----NIGERSLVDAVAAATDKWGADIVF 239

Query: 264 DCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCI 323
           + +G          VVRPGG + LVG+    + + +  A S+E+ I  VFRY+N +   +
Sbjct: 240 EASGSPKAFADLFDVVRPGGAVVLVGLPVEPVALNVPAAISKEVRIETVFRYANIFDRAL 299

Query: 324 ALLASGRVNVKPLIT 338
            L+ASG+V++KPLIT
Sbjct: 300 QLIASGKVDLKPLIT 314

ref|NP_534796.1| xylitol dehydrogenase [Agrobacterium tumefaciens str. C58]
gb|AAL45112.1| xylitol dehydrogenase [Agrobacterium tumefaciens str. C58]
gb|AAK89121.1| AGR_L_1091p [Agrobacterium tumefaciens str. C58]
sp|Q8U7Y1|XYLD_AGRT5 Putative D-xylulose reductase (Xylitol dehydrogenase) (XDH)
pir||G98199 xylitol dehydrogenase [imported] - Agrobacterium tumefaciens (strain C58, Cereon)
pir||AB3087 xylitol dehydrogenase Atu4318 [imported] - Agrobacterium tumefaciens (strain C58, Dupont)
ref|NP_356336.1| hypothetical protein AGR_L_1091 [Agrobacterium tumefaciens str. C58]
(350 aa)

Score: 229 bits (584), Expect: 9.39215e-59
Length: 329, Idn/Pos/Gap = 130/197/7 (39%/59%/2%)

Query:  44 APGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGD 103
            P +VR++   VGICGSDVHY+ HG  G F ++ PM++GHE++G V   G+ VT L++GD
Sbjct:  29 GPKDVRIRTHTVGICGSDVHYYTHGKIGHFVVNAPMVLGHEASGTVIETGSDVTHLKIGD  88

Query: 104 RVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPESVSLE 163
           RV +EPG+P    +  + G YN+ P ++F+ATPP+ G L   V HPAA+ Y+LP++VS  
Sbjct:  89 RVCMEPGIPDPTSRASKLGIYNVDPAVRFWATPPIHGCLTPEVIHPAAFTYKLPDNVSFA 148

Query: 164 EGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRL 223
           EGAM EP ++ + A  RA    G + +V GAGPIG++  + A A G + ++V D+   +L
Sbjct: 149 EGAMVEPFAIGMQAALRARIQPGDIAVVTGAGPIGMMVALAALAGGCAKVIVADLAQPKL 208

Query: 224 AFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVVRPGG 283
                + G    I T ++ E + A  V  A DG   DI  +C+G    +     + RPGG
Sbjct: 209 DIIAAYDG----IETINIRERNLAEAVSAATDGWGCDIVFECSGAAPAILGMAKLARPGG 264

Query: 284 RICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASGRVNVKPLITHRFMG 343
            I LVGM    + V +V   ++E+ +  VFRY+N Y   +AL+ASG+V++KPLI+   + 
Sbjct: 265 AIVLVGMPVDPVPVDIVGLQAKELRVETVFRYANVYDRAVALIASGKVDLKPLISAT-IP 323

Query: 344 LEESSLEAAFETARTAANGAVKVMLTIPE 372
            E+S   A F+ A  A    VK+ + +P+
Sbjct: 324 FEDSI--AGFDRAVEARETDVKLQIVMPQ 350

ref|NP_416288.1| putative dehydrogenase, NAD(P)-binding [Escherichia coli K12]
gb|AAC74844.1| putative oxidoreductase; putative dehydrogenase, NAD(P)-binding [Escherichia coli K12]
pir||F64937 probable L-iditol 2-dehydrogenase (EC 1.1.1.14) b1774 - Escherichia coli (strain K-12)
sp|P77280|YDJJ_ECOLI Hypothetical zinc-type alcohol dehydrogenase-like protein ydjJ
dbj|BAA15572.1| Sorbitol dehydrogenase (EC 1.1.1.14) (L-iditol 2-dehydrogenase). [Escherichia coli]
(347 aa)

Score: 229 bits (583), Expect: 1.16676e-58
Length: 352, Idn/Pos/Gap = 134/202/16 (38%/57%/4%)

Query:  22 NPCGVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDP---  78
           N   +L  P  ++++   +P P   EV +++  VGICGSDVH +  G   P +  DP   
Sbjct:   3 NSKAILQVPGTMKIISAEIPVPKEDEVLIKVEYVGICGSDVHGFESGPFIPPK--DPNQE  60

Query:  79 MIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPP- 137
           + +GHE AG V A+G+ V   + GDRV +EPGVPC  C+ C EG+YN+CP++ F AT P 
Sbjct:  61 IGLGHECAGTVVAVGSRVRKFKPGDRVNIEPGVPCGHCRYCLEGKYNICPDVDFMATQPN 120

Query: 138 VDGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPI 197
             G+L  Y+CHP ++ Y+LP+++   EGA+ EP +V +HA   A    G  +++LGAG I
Sbjct: 121 YRGALTHYLCHPESFTYKLPDNMDTMEGALVEPAAVGMHAAMLADVKPGKKIIILGAGCI 180

Query: 198 GLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGA 257
           GL+     K  GA+ I V D+ ++RLA AE   GA  VIN     + D     QQ  +  
Sbjct: 181 GLMTLQACKCLGATEIAVVDVLEKRLAMAE-QLGATVVINGA---KEDTIARCQQFTEDM 236

Query: 258 QADIALDCAGLESTMRLAMHVVRPGGRICLVGM--GSSAMHVPLVDASSREIDIFGVFRY 315
            ADI  + AG   T++ A ++V  GG+I +VG   G SA++   ++   RE+ I  VFRY
Sbjct: 237 GADIVFETAGSAVTVKQAPYLVMRGGKIMIVGTVPGDSAINFLKIN---REVTIQTVFRY 293

Query: 316 SNTYPTCIALLASGRVNVKPLITHRFMGLE-ESSLEAAFETARTAANGAVKV 366
           +N YP  I  ++SGR +VK ++TH +   + + + E +    R    G +K+
Sbjct: 294 ANRYPVTIEAISSGRFDVKSMVTHIYDYRDVQQAFEESVNNKRDIIKGVIKI 345

ref|XP_327308.1| hypothetical protein [Neurospora crassa]
gb|EAA32925.1| hypothetical protein [Neurospora crassa]
(437 aa)

Score: 228 bits (581), Expect: 2.07497e-58
Length: 409, Idn/Pos/Gap = 143/211/66 (34%/51%/16%)

Query:  26 VLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHES  85
           VL  PR+LR+  R++  P  GE+++ ++  GICGSDV Y+   + G      P+ +GHES
Sbjct:  27 VLHGPRDLRLERRTIEEPELGELQVAVKTTGICGSDVSYYKKFANGDLCACMPLSLGHES  86

Query:  86 AGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFAT----PPVDGS 141
           +GVV A+G  V+   +GDRVALE GV C QC  CR+GRYNLC  ++F ++    P   G+
Sbjct:  87 SGVVVAIGPQVSGFSLGDRVALEVGVACGQCTICRKGRYNLCKKMRFRSSAKSVPHYQGT 146

Query: 142 LARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLN 201
           L   + HPA WC+ LP+ +S +  A+ EPLSV +HA  RA    GS  LVLGAG +GLL 
Sbjct: 147 LQERINHPAIWCHILPDHISFDAAALLEPLSVGIHAVNRASPAPGSTALVLGAGTVGLLT 206

Query: 202 CMVAKAFGASIIVVTDIDDRRLAFA-----ETHA------------------------GA 232
             +A+  G + + +TD+D  R+  A      TH                          +
Sbjct: 207 AAMARQAGCTQVTITDVDQGRVDHAIFKGFATHGYLVPRSHHISSSSSSMFPNSNSNSSS 266

Query: 233 DAVINTRDLDEHDAALVVQQALDGAQA-----------------------DIALDCAGLE 269
            +   +  +    + L  + +LD A+A                       D+  +C G E
Sbjct: 267 GSSTPSDGIATPPSTLSFRSSLDSAKALAADVLTQTQNPVLDRDDEDIGVDVTFECTGKE 326

Query: 270 STMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASG 329
             M  A++  RPGG++ +VGMG+    +PL  A  REIDI GVFRY+NTY T I +L + 
Sbjct: 327 VCMHTALYATRPGGKVIMVGMGTPIQTLPLSVAHLREIDILGVFRYANTYATGIRMLCNQ 386

Query: 330 R--------VNVKPLITHRFMGLEES--SLEAAFETARTAANGAVKVML 368
           +         ++  ++THRF GLE +  + E A  T     N  +KV++
Sbjct: 387 KGSGAGFTLPSLDDMVTHRFKGLENAKGAFELASRTMDNEGNLVLKVVI 435

gb|AAG56763.1| putative oxidoreductase [Escherichia coli O157:H7 EDL933]
dbj|BAB35906.1| putative oxidoreductase [Escherichia coli O157:H7]
ref|NP_310510.1| putative oxidoreductase [Escherichia coli O157:H7]
pir||C90939 probable oxidoreductase ECs2483 [imported] - Escherichia coli (strain O157:H7, substrain RIMD 0509952)
pir||G85787 probable oxidoreductase ydjJ [imported] - Escherichia coli  (strain O157:H7, substrain EDL933)
ref|NP_288210.1| putative oxidoreductase [Escherichia coli O157:H7 EDL933]
(347 aa)

Score: 228 bits (580), Expect: 2.70999e-58
Length: 352, Idn/Pos/Gap = 133/202/16 (37%/57%/4%)

Query:  22 NPCGVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDP---  78
           N   +L  P  ++++   +P P   EV +++  VGICGSDVH +  G   P +  DP   
Sbjct:   3 NSKAILQVPGTMKIISAEIPVPKEDEVLIKVEYVGICGSDVHGFESGPFIPPK--DPNQE  60

Query:  79 MIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPP- 137
           + +GHE AG V A+G+ V   + GDRV +EPGVPC  C+ C EG+YN+CP++ F AT P 
Sbjct:  61 IGLGHECAGTVVAVGSRVRKFKPGDRVNIEPGVPCGHCRYCLEGKYNICPDVDFMATQPN 120

Query: 138 VDGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPI 197
             G+L  Y+CHP ++ Y+LP+++   EG + EP +V +HA   A    G  +++LGAG I
Sbjct: 121 YRGALTHYLCHPESFTYKLPDNMDTMEGTLVEPAAVGMHAAMLADVKPGKKIIILGAGCI 180

Query: 198 GLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGA 257
           GL+     K  GA+ I V D+ ++RLA AE   GA  VIN     + D     QQ  +  
Sbjct: 181 GLMTLQACKCLGATEIAVVDVLEKRLAMAE-QLGATVVINGA---KEDTIARCQQFTEDM 236

Query: 258 QADIALDCAGLESTMRLAMHVVRPGGRICLVGM--GSSAMHVPLVDASSREIDIFGVFRY 315
            ADI  + AG   T++ A ++V  GG+I +VG   G+SA++   ++   RE+ I  VFRY
Sbjct: 237 GADIVFETAGSAVTVKQAPYLVMRGGKIMIVGTVPGASAINFLKIN---REVTIQTVFRY 293

Query: 316 SNTYPTCIALLASGRVNVKPLITHRFMGLE-ESSLEAAFETARTAANGAVKV 366
           +N YP  I  ++SGR +VK ++TH +   + + + E +    R    G +K+
Sbjct: 294 ANRYPVTIEAISSGRFDVKSMVTHIYDYRDVQQAFEESVNNKRDIIKGVIKI 345

ref|NP_754072.1| Hypothetical zinc-type alcohol dehydrogenase-like protein ydjJ [Escherichia coli CFT073]
gb|AAN80637.1| Hypothetical zinc-type alcohol dehydrogenase-like protein ydjJ [Escherichia coli CFT073]
(347 aa)

Score: 228 bits (580), Expect: 2.87298e-58
Length: 352, Idn/Pos/Gap = 133/201/16 (37%/57%/4%)

Query:  22 NPCGVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDP---  78
           N   +L  P  ++++   +P P   EV +++  VGICGSDVH +  G   P +  DP   
Sbjct:   3 NSKAILQVPGTMKIISAEIPVPKEDEVLIKVEYVGICGSDVHGFESGPFIPPK--DPNQE  60

Query:  79 MIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPP- 137
           + +GHE AG V A+G+ V   + GDRV +EPGVPC  C+ C EG+YN+CP++ F AT P 
Sbjct:  61 IGLGHECAGTVVAVGSRVRKFKPGDRVNIEPGVPCGHCRYCLEGKYNICPDVDFMATQPN 120

Query: 138 VDGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPI 197
             G+L  Y+CHP ++ Y+LP+++   EGA+ EP +V +HA   A    G  +++LGAG I
Sbjct: 121 YRGALTHYLCHPESFTYKLPDNMDTMEGALVEPAAVGMHAAMLADVKPGKKIIILGAGCI 180

Query: 198 GLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGA 257
           GL+     K  GA+ I V D+ ++RL  AE   GA  VIN     + D     QQ  +  
Sbjct: 181 GLMTLQACKCLGATEIAVVDVLEKRLTMAE-QLGATVVINGA---KEDTIARCQQFTEDM 236

Query: 258 QADIALDCAGLESTMRLAMHVVRPGGRICLVGM--GSSAMHVPLVDASSREIDIFGVFRY 315
            ADI  + AG   T++ A ++V  GG+I +VG   G SA++   ++   RE+ I  VFRY
Sbjct: 237 GADIVFETAGSAVTVKQAPYLVMRGGKIMIVGTVPGDSAINFLKIN---REVTIQTVFRY 293

Query: 316 SNTYPTCIALLASGRVNVKPLITHRFMGLE-ESSLEAAFETARTAANGAVKV 366
           +N YP  I  ++SGR +VK ++TH +   + + + E +    R    G +K+
Sbjct: 294 ANRYPVTIEAISSGRFDVKSMVTHIYDYRDVQQAFEESVNNKRDIIKGVIKI 345

ref|ZP_00121711.2| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Bifidobacterium longum DJO10A]
(346 aa)

Score: 227 bits (579), Expect: 3.45186e-58
Length: 339, Idn/Pos/Gap = 130/193/10 (38%/56%/2%)

Query:  35 VMLRSVPA---PAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEA  91
           + +R VP    P PGE+R+    VG+CGSD+HY+ HG  G + +  PMI+GHE+AG V  
Sbjct:  12 INVREVPDVKDPGPGELRIAPHTVGVCGSDLHYYTHGRVGKYVVEQPMILGHEAAGTVLE  71

Query:  92 LGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAA 151
           +G GVT  + GDRVALEPG+P +  +  R G YN+ P ++FFATPP+DG L   V HPAA
Sbjct:  72 VGPGVTDFKPGDRVALEPGIPDMTSRASRLGMYNVDPAVRFFATPPIDGCLCEEVIHPAA 131

Query: 152 WCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGAS 211
           + Y LP+S+S  EGA+ EP +V + A  +A    G + +V G+G +G+L    A A GAS
Sbjct: 132 FTYHLPDSMSFGEGALLEPTAVGMWAATKARIKPGDVCVVTGSGTVGMLTASAALAGGAS 191

Query: 212 IIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLEST 271
            ++V+D+   +L       G   V    DL   D    V++   G  AD+A +C+G    
Sbjct: 192 KVLVSDVSSIKLGIIGQIPGVIPV----DLTTEDLVERVREETAGWGADVAFECSGAPKA 247

Query: 272 MRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASGRV 331
                 ++ PGG   LVG+  + + + + +  + E+ I  +FRY+N Y   I L+ SGR+
Sbjct: 248 YETFWKLIAPGGCAVLVGIPVNPVPIDVTELQATEVRIENIFRYANVYQKAIDLVDSGRL 307

Query: 332 NVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLTI 370
           N+KP IT  F        +AAF+       G +K+ +T+
Sbjct: 308 NLKPFITDTF---AMKDAKAAFDRMDEGRPGDIKLQITV 343

gb|EAA53894.1| hypothetical protein MG09857.4 [Magnaporthe grisea 70-15]
ref|XP_365012.1| hypothetical protein MG09857.4 [Magnaporthe grisea 70-15]
(371 aa)

Score: 226 bits (575), Expect: 9.55296e-58
Length: 364, Idn/Pos/Gap = 145/213/23 (39%/58%/6%)

Query:  22 NPCGVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMII  81
           NP   +    +L+ +  S+ +P PGEV L ++C G+CGSDVH+W  G+ G   +    I+
Sbjct:   6 NPSLQVTADHQLKQVEASILSPGPGEVLLHVKCTGVCGSDVHFWKTGAIGTLVVEGDCIL  65

Query:  82 GHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGS 141
           GHE+AG+V + G  VT+L+ GDRVA+EPGVPC +C  C EGRYNLC  ++F    P  G+
Sbjct:  66 GHEAAGIVLSTGQDVTTLKPGDRVAIEPGVPCNKCFLCSEGRYNLCQEVQFAGVWPYHGT 125

Query: 142 LARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLN 201
           L RY  HPA W ++LP+S+S  EGA+ EPLSV +H  R AG ++G   ++ GAGPIGL+ 
Sbjct: 126 LQRYKVHPARWLHKLPDSLSYAEGALLEPLSVVLHGIRVAGLSLGRGAVICGAGPIGLIA 185

Query: 202 CMVAKAFGASIIVVTDIDDRRLAFAETHAGADA---VINTRDLDEHDAALVVQQALDG-- 256
              A+A GA  IV+TD++ RRL FA     +     V  T+  +E+   +     L G  
Sbjct: 186 LAAARASGAHPIVITDVEPRRLEFAREFVPSCQTYRVDPTQSPEENARGIRALFGLKGGA 245

Query: 257 -------AQADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAM-HVPLVDASSREID 308
                  +   + L+C G+ES++  A    R GG + ++G+G S M ++P +  S  EID
Sbjct: 246 VPDPDEYSAPPVVLECTGVESSVCTAAFTARRGGIVVVIGVGKSTMNNLPFMHLSLAEID 305

Query: 309 IFGVFRYSNTYPTCIALLASGRV-NVKPLITHRFMGLEESSLEAAFETARTAA---NGAV 364
           +  + RY +T+P  IA L SG + ++K L+TH F       LE A E    A+   NG++
Sbjct: 306 LRFINRYRDTWPAGIACLESGILPDLKKLVTHVF------PLEKAIEGLTLASDPRNGSI 359

Query: 365 KVML 368
           KV +
Sbjct: 360 KVQI 363

ref|YP_216296.1| Hypothetical zinc-type alcohol dehydrogenase-like [Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67]
gb|AAX65215.1| Hypothetical zinc-type alcohol dehydrogenase-like [Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67]
(347 aa)

Score: 225 bits (574), Expect: 1.37905e-57
Length: 355, Idn/Pos/Gap = 136/201/22 (38%/56%/6%)

Query:  22 NPCGVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDP---  78
           N   +L  P  ++++   +P P   EV +++  VGICGSDVH +  G   P +  DP   
Sbjct:   3 NSKAILKTPGTMKIIAADIPVPKDNEVLIKVEYVGICGSDVHGFESGPFIPPK--DPNQE  60

Query:  79 MIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPP- 137
           + +GHE AG V A+G  V+  +  DRV +EPGVPC  C+ C EG+YN+CP++ F  T P 
Sbjct:  61 IGLGHECAGTVIAVGNRVSKFKPVDRVNIEPGVPCGHCRYCLEGKYNICPDVDFMETQPN 120

Query: 138 VDGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPI 197
             G+L  Y+CHP ++ Y+LP+++   EGA+ EP +V +HA   A    G  +++LGAG I
Sbjct: 121 YRGALTHYLCHPESFTYKLPDNMDTMEGALVEPAAVGMHAAMLADVKPGKKIVILGAGCI 180

Query: 198 GLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGA 257
           GL+     K  GA+ I V D+ ++RLA AE   GA  VIN     + D     QQ  D  
Sbjct: 181 GLMTLQACKCLGATNIAVVDVLEKRLAMAE-RLGATTVINGA---KEDTVARCQQFTDDM 236

Query: 258 QADIALDCAGLESTMRLAMHVVRPGGRICLVGM--GSSAMHVPLVDASSREIDIFGVFRY 315
            ADI  + AG   T + A ++V  GG+I +VG   G SA++   ++   RE+ I  VFRY
Sbjct: 237 GADIVFETAGSAVTTQQAPYLVMRGGKIMIVGTVAGDSAINFLKIN---REVSIQTVFRY 293

Query: 316 SNTYPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETA----RTAANGAVKV 366
           +N YP  I  ++SGR +VK ++TH +   +   ++ AFE +    R    G +KV
Sbjct: 294 ANRYPVTIDAISSGRFDVKSMVTHIY---DYKDVQRAFEESVNNKRDIIKGVIKV 345

gb|EAA60497.1| hypothetical protein AN4336.2 [Aspergillus nidulans FGSC A4]
ref|XP_408473.1| hypothetical protein AN4336.2 [Aspergillus nidulans FGSC A4]
(427 aa)

Score: 221 bits (564), Expect: 2.25683e-56
Length: 355, Idn/Pos/Gap = 132/202/31 (37%/56%/8%)

Query:  16 VLNEKANPCGVLVRP-RELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFR  74
           +L +K     +   P  +LRV+   +P  AP    + +R  GICGSDVH+W HG  GP  
Sbjct:   3 ILQKKPKNIAIHTSPVHDLRVVDCEIPRLAPDGCLIHVRATGICGSDVHFWKHGRIGPMV  62

Query:  75 LHDPMIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFA 134
           +     +GHESAGVV         LQVGD V            R + G+Y+ CP++ FF+
Sbjct:  63 VTGDNGLGHESAGVV---------LQVGDAVT-----------RFKPGKYHACPDVVFFS 102

Query: 135 TPPVDGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGA 194
           TPP  G+L RY  HP AW +RLP+ VS EEGA+ EPL+VA+    R+G  +   +++ GA
Sbjct: 103 TPPHHGTLRRYHAHPEAWLHRLPDHVSFEEGALLEPLTVALAGIDRSGLRLADPLVICGA 162

Query: 195 GPIGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAG--ADAVINTRDLDEHDAALVVQQ 252
           GPIGL+  + A A GA+ IV+TDID  RLA A+         ++  ++  +  A  +VQ+
Sbjct: 163 GPIGLVTLLAANAAGAAPIVITDIDSNRLAKAKELVPRVQPVLVQKQESPQELAGRIVQR 222

Query: 253 ALDGAQADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGV 312
              G +A + L+C G+ES++   ++  R GG + ++ +G    ++P +  S++EID+   
Sbjct: 223 L--GQEARLVLECTGVESSVHAGIYATRFGGTVFVIRVGKDFQNIPFMHMSAKEIDLRFQ 280

Query: 313 FRYSNTYPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVM 367
           +RY + YP  I+L+ +G V++KPL++HR+       LE   E   TA+N A K +
Sbjct: 281 YRYHDIYPKAISLVNAGLVDLKPLVSHRY------KLEDGLEAFATASNTAAKAI 329

emb|CAG85513.1| unnamed protein product [Debaryomyces hansenii CBS767]
ref|XP_457507.1| unnamed protein product [Debaryomyces hansenii]
(371 aa)

Score: 220 bits (560), Expect: 5.99054e-56
Length: 356, Idn/Pos/Gap = 124/203/11 (34%/57%/3%)

Query:  21 ANPCGVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMI  80
           +NPC ++    +L      +P   P +V++ ++C GICGSD+H W  G  G   + + ++
Sbjct:  16 SNPCLIVTPDHKLIAGNAPIPQCQPNQVKIHIKCTGICGSDIHLWKEGGIGDLVVTENLV  75

Query:  81 IGHESAGVVEALGAGVTS-LQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVD 139
           +GHE+AG V  +G  VT+ ++VGDRVA+EP  PC++C  C +G YNLC ++ F   PP +
Sbjct:  76 LGHETAGQVIEVGREVTNDIKVGDRVAIEPQAPCMKCYLCLDGHYNLCEDVAFLGVPPTN 135

Query: 140 GSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRA-GTTIGSLVLVLGAGPIG 198
           GS+ RY+C    + ++LP+++S E+GA+ E +SVA H  R+A G   G   ++ G GPIG
Sbjct: 136 GSMQRYLCTDPNFVHKLPDNMSYEQGALSEIVSVAFHGIRKAGGLNPGEPCMIAGCGPIG 195

Query: 199 LLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVI-NTRDLDEHDAALVVQQALDGA 257
           L   ++A   GA  IVV+DI D RL FA+T   +     N   +     A  +++     
Sbjct: 196 LATLLLADVSGAYPIVVSDISDERLEFAKTLVPSVMTYKNDTSISPKKNAKNIRKMFGTT 255

Query: 258 Q---ADIALDCAGLESTMRLAMHVVRPGGRICLVGM-GSSAMH-VPLVDASSREIDIFGV 312
           +     + L+C G  S++    +VVR  G + ++G+ G + +   P +  S  E+D+  +
Sbjct: 256 EYVMPPVVLECTGFASSINSCCYVVRRNGVLTILGVSGKNELDGFPFMPLSLGEVDVRFI 315

Query: 313 FRYSNTYPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVML 368
            RY++T+P  I L++SG++NV   +TH F  LEE++   A E         +KVM+
Sbjct: 316 NRYTDTWPAVINLISSGKINVDKFVTHVFQ-LEEAA--KALECVVDRNVPTIKVMI 368

ref|ZP_00092045.2| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Azotobacter vinelandii]
(312 aa)

Score: 219 bits (557), Expect: 1.22772e-55
Length: 318, Idn/Pos/Gap = 133/192/13 (41%/60%/4%)

Query:  55 VGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCL 114
           +G+CGSDVHY+ HG  G F +  PM++GHE+AG V  +G+ VT L  GDRV +EPG+P  
Sbjct:   1 MGVCGSDVHYYTHGRIGHFIVDQPMVLGHEAAGTVIEVGSNVTHLAKGDRVCMEPGIPNP  60

Query: 115 QCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVA 174
           + +  R G YN+ P++ F+ATPPV G L   V HPAA+ Y+LP+ VS  EGA+ EP ++ 
Sbjct:  61 RSKASRLGLYNVDPSVVFWATPPVHGCLTPEVVHPAAFAYKLPDHVSFAEGALVEPFAIG 120

Query: 175 VHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADA 234
           + A  +A    G + +V+GAG IG++  + A A GAS ++V+D+   +LA A+ + G  A
Sbjct: 121 MQAAVKARIKPGDVAVVIGAGTIGMMTALAALAGGASQVLVSDLMVEKLAIAQRYEGITA 180

Query: 235 VINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSA 294
           V N R+    D    V +A  G  AD+  + +G       A+  V PGG + LVGM    
Sbjct: 181 V-NVREQSLQDK---VAEATGGWGADVVFEASGSARAYGDALAAVCPGGALVLVGMPVEP 236

Query: 295 MHVPLVDASSREIDIFGVFRYSNTYPTCIALLASGRVNVKPLITHRF---MGLEESSLEA 351
           +   +V A ++EI I  VFRY+N Y   + L+ASG+V++KPLI+  F    G+E      
Sbjct: 237 VLFDVVAAQAKEIRIETVFRYANVYERAVNLIASGKVDLKPLISATFPFERGVE------ 290

Query: 352 AFETARTAANGAVKVMLT 369
           AFE A +A  G VKV +T
Sbjct: 291 AFERAASAQPGDVKVQIT 308

gb|EAA66977.1| hypothetical protein AN8552.2 [Aspergillus nidulans FGSC A4]
ref|XP_412689.1| hypothetical protein AN8552.2 [Aspergillus nidulans FGSC A4]
(363 aa)

Score: 216 bits (549), Expect: 1.11107e-54
Length: 327, Idn/Pos/Gap = 132/190/6 (40%/58%/1%)

Query:  21 ANPCGVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMI  80
           ANP   +    +++++   V  P  GEV + ++  G+CGSD+H+W  G  G    H   I
Sbjct:   5 ANPSLQVTADHQIKLVEAPVHEPGKGEVLVHIKATGVCGSDIHFWKTGRIGELIFHGDCI  64

Query:  81 IGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDG 140
           IGHE+AGVV   G GVT LQ GDRVA+EPGVPC  C  C EGRYNLC ++ F    P  G
Sbjct:  65 IGHEAAGVVLKCGEGVTDLQPGDRVAIEPGVPCENCFLCDEGRYNLCEDVAFAGVYPYAG 124

Query: 141 SLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLL 200
           ++ RY  HPA W ++LP S+S  +GA+ EPLSV +   + A   +G  V++ GAGPIGL+
Sbjct: 125 TIQRYKVHPAKWLHKLPPSLSYLDGALLEPLSVVMRGIQVAQLELGRGVVICGAGPIGLI 184

Query: 201 NCMVAKAFGASIIVVTDIDDRRLAFAETHAGA-DAVINTRDLDEHDAALVVQQALDGAQ- 258
               A+A GA  +V+TDID  RL+FA           N   LD    A  ++      + 
Sbjct: 185 AAAAARASGAHPVVITDIDPSRLSFARRFLPTIQTYQNNPTLDAQGNAKAIRALFGDNEY 244

Query: 259 --ADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAM-HVPLVDASSREIDIFGVFRY 315
              D  L+C G+ES++  A +  R GG + +VG+G   + +VP +  S  EID+  + RY
Sbjct: 245 NAPDRVLECTGVESSICTAAYTARRGGLVVVVGVGKEIINNVPFMHLSLAEIDLKFINRY 304

Query: 316 SNTYPTCIALLASGRV-NVKPLITHRF 341
            +T+P  I+ +A+G + ++KPLI+H F
Sbjct: 305 RDTWPRAISCMAAGIITDLKPLISHTF 331

gb|EAL23595.1| hypothetical protein CNBA2420 [Cryptococcus neoformans var. neoformans B-3501A]
gb|AAW40827.1| sorbitol dehydrogenase, putative [Cryptococcus neoformans var. neoformans JEC21]
ref|XP_566646.1| sorbitol dehydrogenase, putative [Cryptococcus neoformans var. neoformans JEC21]
(416 aa)

Score: 214 bits (546), Expect: 2.73587e-54
Length: 417, Idn/Pos/Gap = 148/210/49 (35%/50%/11%)

Query:   2 SEMETELEESDAGSVLNEKANPCGVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSD  61
           + +  E ++     V   K+N   +L  P +     +SVP   P EV ++++  GICGSD
Sbjct:   3 TSLPLESKQPPKPEVFEAKSNLGFMLHSPLKTSFEEQSVPEIGPDEVLVEIKKTGICGSD  62

Query:  62 VHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTS-----------------------  98
           VH++  G  G   L + M +GHES+G+V  LG+ +                         
Sbjct:  63 VHFYNTGKMGLAALTESMCLGHESSGIVVQLGSNIVQQAARSNVMATARGEAEESNKGTV 122

Query:  99 ----LQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPP-VDGSLARYVCHPAAWC 153
               LQVGD+VALEPGV C  C  C+ G+Y +C ++ F A PP   G+L RY   PA   
Sbjct: 123 SNRPLQVGDKVALEPGVTCRMCVDCKGGKYQICEHMIFAAYPPSTGGTLQRYYALPADLV 182

Query: 154 YRLPESVSLEEGAMCEPLSVAVHANRR-AGTTIGSLVLVLGAGPIGLLNCMVAKAFGASI 212
           Y LP++V L  GAM EPLSVA HA     G   G  VL+ GAGP+GLL   VAK  GA  
Sbjct: 183 YPLPDNVDLSFGAMMEPLSVATHAVANIGGMRTGWNVLITGAGPVGLLAMAVAKGLGAGK 242

Query: 213 IVVTDIDDRRLAFAETHAGADAVINT-RDLDEHDAALVVQQALD-----GAQA------D 260
           ++  DI++ RL FA+ +A  D  I    +  E      V+ A D     G  A      D
Sbjct: 243 VIAVDINEERLHFAKQYAATDTYIPIPPNEGESRGDHAVRAAEDLLRSTGTPARGPGSID 302

Query: 261 IALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRY-SNTY 319
           + +D  G E+ + + ++ ++PGG    +G G   + VP+    + EI I G +RY S  Y
Sbjct: 303 LVVDATGAETCVLMGLNAIKPGGIYVQIGFGPPNVSVPMFRIVTNEITIRGAWRYGSGDY 362

Query: 320 PTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTA----ANGAVKVMLTIPE 372
           P  I ++A G VN+KPL+TH F    E +LE AFE  +        G +K ++  PE
Sbjct: 363 PLAIDMVARGLVNLKPLLTHTFKF--EDALE-AFEITKNGRDKNGKGVIKCVIDGPE 416

ref|NP_435515.1| IdnD L-idonate 5-dehydrogenase [Sinorhizobium meliloti 1021]
gb|AAK64927.1| IdnD L-idonate 5-dehydrogenase [Sinorhizobium meliloti 1021]
pir||E95295 IdnD L-idonate 5-dehydrogenase [imported] - Sinorhizobium meliloti (strain 1021) magaplasmid pSymA
(343 aa)

Score: 214 bits (545), Expect: 3.69442e-54
Length: 318, Idn/Pos/Gap = 122/185/11 (38%/58%/3%)

Query:  26 VLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHES  85
           V+   ++LRV   +V  P PGEV +++   GICGSD+HY+ HG  G  RL +PMI+GHE 
Sbjct:   5 VIHTAKDLRVEECAVEKPGPGEVEIRLAAGGICGSDLHYYNHGGFGTVRLKEPMILGHEV  64

Query:  86 AGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFAT----PPVDGS 141
           +G V ALG GV+ L +GD VA+ P  PC  C  C +G  N C +++F+ +    P + G+
Sbjct:  65 SGHVAALGEGVSDLAIGDLVAVSPSRPCGACDYCLKGLPNHCFHMRFYGSAMPFPHIQGA 124

Query: 142 LARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLN 201
               +   A+ C +  E +S  E AM EPLSV +HA RRAG  +G  VLV G GPIG L+
Sbjct: 125 FRERLVAKASQCVK-AEGLSAGEAAMAEPLSVTLHATRRAGEMLGKRVLVTGCGPIGTLS 183

Query: 202 CMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADI 261
            + A+  GA+ IV  D+ +R L FA    GAD  +N  +    D   +V  + +    D+
Sbjct: 184 ILAARRAGAAEIVAADLSERALGFARA-VGADRTVNLSE----DRDGLVPFSENKGTFDV 238

Query: 262 ALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPT 321
             +C+G +  +   +  +RP G I  +G+G   M +P++  +++E+D+ G FR+   + T
Sbjct: 239 LYECSGAQPALVAGIQALRPRGVIVQLGLGGD-MALPMMAITAKELDLRGSFRFHEEFAT 297

Query: 322 CIALLASGRVNVKPLITH 339
            + L+  G ++VKPLITH
Sbjct: 298 AVKLMQGGLIDVKPLITH 315

ref|NP_534572.1| zinc-binding dehydrogenase [Agrobacterium tumefaciens str. C58]
gb|AAL44888.1| zinc-binding dehydrogenase [Agrobacterium tumefaciens str. C58]
gb|AAK89344.1| AGR_L_1538p [Agrobacterium tumefaciens str. C58]
pir||AB3059 zinc-binding dehydrogenase Atu4087 [imported] - Agrobacterium tumefaciens (strain C58, Dupont)
pir||F98227 L-idonate 5-dehydrogenase [imported] - Agrobacterium tumefaciens (strain C58, Cereon)
ref|NP_356559.1| hypothetical protein AGR_L_1538 [Agrobacterium tumefaciens str. C58]
(343 aa)

Score: 213 bits (543), Expect: 4.94736e-54
Length: 313, Idn/Pos/Gap = 122/184/11 (38%/58%/3%)

Query:  31 RELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVE  90
           +++R+  R    P PGEVRL++   GICGSD+HY+ HG  G  RL +PM++GHE + V+E
Sbjct:  10 KDVRIEDRPEEKPGPGEVRLRLARGGICGSDLHYYNHGGFGAVRLREPMVLGHEVSAVIE  69

Query:  91 ALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFAT----PPVDGSLARYV 146
            LG GV  L++G  VA+ P  PC  C+ C+EG +N C N++F+ +    P + G+    +
Sbjct:  70 ELGEGVEGLKIGGLVAVSPSRPCRTCRFCQEGLHNQCLNMRFYGSAMPFPHIQGAFREIL 129

Query: 147 CHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAK 206
              A  C    + +S  E AM EPL+V +HA RRAG  +G  VLV G GPIG+L+ + A+
Sbjct: 130 VADALQCVP-ADGLSAGEAAMAEPLAVTLHATRRAGDLLGKRVLVTGCGPIGILSILAAR 188

Query: 207 AFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCA 266
             GA+ IV TD+ D  L  A   AGAD VIN++  DE DA  +     +    DI  +C+
Sbjct: 189 RAGAAEIVATDLSDFTLGKAR-EAGADRVINSK--DEPDA--LAAYGANKGTFDILYECS 243

Query: 267 GLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALL 326
           G    +   +  +RP G I  +G+G   M +P++  +++E+D+ G FR+   + T + L+
Sbjct: 244 GAAVALAGGITALRPRGIIVQLGLGGD-MSLPMMAITAKELDLRGSFRFHEEFATGVELM 302

Query: 327 ASGRVNVKPLITH 339
             G ++VKP IT 
Sbjct: 303 RKGLIDVKPFITQ 315

gb|EAA08893.2| ENSANGP00000011286 [Anopheles gambiae str. PEST]
ref|XP_313336.2| ENSANGP00000011286 [Anopheles gambiae str. PEST]
(261 aa)

Score: 212 bits (540), Expect: 1.23872e-53
Length: 260, Idn/Pos/Gap = 114/164/1 (43%/63%/0%)

Query:  74 RLHDPMIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFF 133
           +L  P+++GHESAGVV  +G+ VT L+VGDRVA+EP   C  C  C+ G+YN+C N K  
Sbjct:   2 KLIRPLVLGHESAGVVRKVGSAVTHLKVGDRVAIEPAAGCRTCDLCKVGKYNICLNGKHC  61

Query: 134 ATPPVDGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLG 193
            T   DG+ + +  H A  C++LP+ V++EEGA+ EPL+V V+A RRA   +GS V++ G
Sbjct:  62 PTKNHDGNCSNFFSHYADCCFKLPDHVTMEEGALLEPLAVGVYAGRRADIRLGSRVVIFG 121

Query: 194 AGPIGLLNCMVAKAFGASIIVVTDIDDRRLAF-AETHAGADAVINTRDLDEHDAALVVQQ 252
           AGPIGL++ +VAKA GA+  VV D+    +   A    GA AVI   + D  D  +   Q
Sbjct: 122 AGPIGLISLVVAKAMGATRTVVLDLARAGVRLEAAKKLGATAVIPIGEQDSEDELVKRIQ 181

Query: 253 ALDGAQADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGV 312
              G  AD AL+C G E  MR ++   R  G +CLVG+G+  + +P+VDA SRE+ I  V
Sbjct: 182 EALGGPADRALECTGSEPGMRTSIRATRNAGIVCLVGLGNEEVRLPMVDAISREVQIITV 241

Query: 313 FRYSNTYPTCIALLASGRVN 332
            RY++ YP  + +++SG V+
Sbjct: 242 MRYNHDYPAALEIVSSGYVD 261

ref|NP_771918.1| IdnD L-idonate 5-dehydrogenase [Bradyrhizobium japonicum USDA 110]
dbj|BAC50543.1| IdnD L-idonate 5-dehydrogenase [Bradyrhizobium japonicum USDA 110]
(343 aa)

Score: 211 bits (538), Expect: 2.20296e-53
Length: 348, Idn/Pos/Gap = 131/199/14 (37%/57%/4%)

Query:  26 VLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHES  85
           V+  P++LR+     PAP PGEVR+++   GICGSD+HY+ HG  G  R+  PM +GHE 
Sbjct:   5 VIHAPKDLRIDSYPDPAPGPGEVRVKIANGGICGSDLHYYHHGGFGVVRIQQPMALGHEI  64

Query:  86 AGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFAT----PPVDGS 141
           AGVV A+G GVTS++ G RVA+ P  PC +C  C+EG  N C +++F  +    P V G 
Sbjct:  65 AGVVAAVGDGVTSVKPGTRVAVNPSKPCGKCLHCQEGMRNQCLDMRFLGSAMRFPHVQGG 124

Query: 142 LARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLN 201
              ++   A     + + +SL E A+ EPL+V +HA ++AG  +G  VL+ G GPIG L 
Sbjct: 125 FREFLTIDATQAVPIADELSLAEAAVAEPLAVCLHAGKQAGPLLGKRVLITGCGPIGALM 184

Query: 202 CMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADI 261
            +V++  GAS IVVTD+ D  LA A       A+    ++  H  AL   +A  G   D 
Sbjct: 185 ILVSRFGGASEIVVTDVADAPLAVARKLGATHAI----NVATHATALDPWRAGKGV-FDT 239

Query: 262 ALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPT 321
             + +G ++ +R A+ V+RPG  +  +G+G   M +P+    ++E+ + G FR+   +  
Sbjct: 240 LFEASGNQAALRTALDVLRPGATLVQLGLGGE-MTLPINSIVAKELQLRGTFRFDPEFEL 298

Query: 322 CIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLT 369
            + L+  G ++VKPLIT   M  E +   AAFE A   +  ++KV L+
Sbjct: 299 AVRLMGEGLIDVKPLITAT-MPFENAV--AAFELASDRSQ-SMKVQLS 342

ref|XP_329095.1| hypothetical protein [Neurospora crassa]
gb|EAA36300.1| hypothetical protein [Neurospora crassa]
(412 aa)

Score: 206 bits (525), Expect: 6.96939e-52
Length: 409, Idn/Pos/Gap = 141/208/69 (34%/50%/16%)

Query:  26 VLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHES  85
           VL   R+L V  R +P  +P +V + ++  G+CGSD+HY+ H   G  ++H+P+ +GHES
Sbjct:   9 VLHGARDLSVESRPLPTLSPTDVLISIKSTGLCGSDLHYYTHFRNGDIQVHEPLTLGHES  68

Query:  86 AGVVEALGAGVTS----LQVGDRVALEPGVPCLQCQRC---------------------- 119
           +G++ A+G+   S    L VGDRVALE G PC  C+ C                      
Sbjct:  69 SGIITAIGSPSVSSEYGLNVGDRVALEVGQPCEACELCCPPGTGPIGNYSGGHGEESGGK 128

Query: 120 ------REGRYNLCPNIKFFAT-------PPVDGSLARYVCHPAAWCYRLPESVSLEEGA 166
                    RYN+C  ++F ++       P   G+L   V HPA WC++LPESV    GA
Sbjct: 129 GGESTTTTSRYNICRAMRFRSSAKGWPQFPHAQGTLQEVVAHPAKWCHKLPESVDYTLGA 188

Query: 167 MCEPLSVAVHANRRAGT----------------TIGSLVLVLGAGPIGLLNCMVAKAF-- 208
           + EPL+VA+HA  RAG                      VLV GAG +GLL   V K+   
Sbjct: 189 LAEPLAVAMHAAGRAGIPSCVPHSSSSMTSSRGAARVKVLVFGAGAVGLLCAAVCKSITK 248

Query: 209 GASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGL 268
           G +I+V+ DI   R+ FA  +  ADA +     D+      +++ L+ A++ +A    G 
Sbjct: 249 GDAIVVIADIQADRVKFAVENGFADAAVVVPISDKRPET--IEEKLEYAKS-VAERVKGA 305

Query: 269 ESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLAS 328
           E    L      PGG+I ++GMG+    +P+  AS +E+D+ GVFRY+N YP  I LLA 
Sbjct: 306 ELVKGLGGQATAPGGKIMIIGMGNPIQTLPISAASLKEVDLLGVFRYANAYPKVIELLAR 365

Query: 329 GR---VNVKPLITHRFMGLEESSLEAAFETAR----TAANGAVKVMLTI 370
           G     ++  L+T R+ GLE  S+  AF+ A        N  +KVM+ +
Sbjct: 366 GDPHLPDLSKLVTQRYSGLE--SIPMAFDMAARVKDNEGNLVLKVMIDM 412

gb|AAH56799.1| Hypothetical protein MGC63674 [Danio rerio]
ref|NP_956910.1| hypothetical protein MGC63674 [Danio rerio]
(594 aa)

Score: 204 bits (520), Expect: 2.29814e-51
Length: 188, Idn/Pos/Gap = 100/131/0 (53%/69%/0%)

Query:  19 EKANPCGVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDP  78
           +K N   VL    +LR+  R +P P P +V LQM  VGICGSDVHYW +G  G F +  P
Sbjct:   2 DKDNLSVVLHAKGDLRLEQRPIPEPGPNDVLLQMHSVGICGSDVHYWQNGRIGDFVVKQP  61

Query:  79 MIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPV 138
           MI+GHE++G V  +G+ VT L+ GDRVA+EPGVP    +  + G YNL P+I F ATPP 
Sbjct:  62 MILGHEASGRVVKVGSAVTHLKPGDRVAVEPGVPREVDEFVKSGHYNLSPSIFFCATPPD 121

Query: 139 DGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIG 198
           DG+L RY  H A++CY+LP++V+ EEGA+ EPLSV +HA RRAG T+GS V V GAGPIG
Sbjct: 122 DGNLCRYYKHSASFCYKLPDNVTYEEGALIEPLSVGIHACRRAGVTLGSSVFVCGAGPIG 181

Query: 199 LLNCMVAK 206
           L++ +  +
Sbjct: 182 LVSLLAVQ 189

ref|NP_522509.1| PUTATIVE L-IDONATE 5-DEHYDROGENASE OXIDOREDUCTASE PROTEIN [Ralstonia solanacearum GMI1000]
emb|CAD18099.1| PUTATIVE L-IDONATE 5-DEHYDROGENASE OXIDOREDUCTASE PROTEIN [Ralstonia solanacearum]
(344 aa)

Score: 203 bits (517), Expect: 5.20587e-51
Length: 311, Idn/Pos/Gap = 123/180/10 (39%/57%/3%)

Query:  32 ELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEA  91
           +LR+     P   P ++R+Q+R  GICGSD+HY+ HG  G  R+ +PM++GHE AG VE 
Sbjct:  11 DLRIEDIDTPEVQPDQLRVQVRFGGICGSDLHYYNHGGFGTVRVKEPMVLGHEVAGRVEE  70

Query:  92 LGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFA----TPPVDGSLARYVC 147
           +G GV     GDRVA+ P  PC QC  C++G  N C +++++     TP V G+  R + 
Sbjct:  71 IGPGVHRHAKGDRVAISPSRPCGQCHYCQQGLQNHCLDMRYYGSAMRTPHVQGAFRREIV 130

Query: 148 HPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKA 207
              +  +RL +++S +EGAM EPLSVA+HA RRAG  +G  VLV G GPIG L  + A+ 
Sbjct: 131 IDESQAHRLADTLSDQEGAMAEPLSVALHAVRRAGPLLGKRVLVTGCGPIGALIVVAARR 190

Query: 208 FGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAG 267
            GA+ I+VTD+    L  A    GAD  IN  +  +     +     D  Q D+  + +G
Sbjct: 191 AGAAEIIVTDMGAYPLK-AAVAVGADVTINVAEQPDG----LKPYTTDKGQIDVLFEASG 245

Query: 268 LESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLA 327
            E  +R A+  +RP G I  VG+G   M +PL    ++E+++ G FR+   +   + LL 
Sbjct: 246 NERALRGAIDALRPRGIIVQVGLGGE-MTLPLNAIVAKELELRGAFRFHEEFAMAVELLN 304

Query: 328 SGRVNVKPLIT 338
            G V+VKPLI+
Sbjct: 305 KGLVDVKPLIS 315

gb|EAA73573.1| hypothetical protein FG04247.1 [Gibberella zeae PH-1]
ref|XP_384423.1| hypothetical protein FG04247.1 [Gibberella zeae PH-1]
(356 aa)

Score: 201 bits (512), Expect: 1.92933e-50
Length: 303, Idn/Pos/Gap = 113/167/10 (37%/55%/3%)

Query:  20 KANPCGVLVRPRELRVMLRSVPA-PAPGEVRLQMRCVGICGSDVHYWWHGSCG-PFRLHD  77
           + NP  +L  P + R   R  P    P +V +++   G+CGSDVH+W  G          
Sbjct:   3 ETNPSCLLYGPGDARFEDRPFPQIEDPHDVIVKIAYTGVCGSDVHFWTEGGFARKVSQQQ  62

Query:  78 PMIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPP 137
           P+++GHE++G++  +G  V+ L+ GDRVA+EPG PC  C  C+ GRYNLC  +KF A PP
Sbjct:  63 PLVMGHEASGIIYKVGPAVSQLKPGDRVAIEPGFPCKSCNYCKSGRYNLCRKMKFAADPP 122

Query: 138 -VDGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGP 196
              G+L+R+   P  + Y++P S+SLEE  + EPL VAVH  R A    G  V+V GAG 
Sbjct: 123 FTHGTLSRFFKIPEDFTYKVPHSISLEEAVLVEPLGVAVHGVRLADIRPGQNVIVQGAGT 182

Query: 197 IGLLNCMVAKAFGASIIVVTDIDDRRLAFA----ETHAGADAVINTRDLDEHDAALVVQQ 252
           +G L    AKA+GA  +V+TDI+  +L+FA    E +     +  T    E +AA + Q+
Sbjct: 183 VGCLTAATAKAYGAKTVVITDINPEKLSFAKGVVECYTFQPRLYAT---PEQEAARLKQE 239

Query: 253 ALDGAQADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGV 312
           A     AD  L+C G+E +    +  + PGG    +G+G     +PL     +E+ +   
Sbjct: 240 AGFDLGADTVLECTGVEISAHTGILALAPGGVFVQIGLGKPIQSLPLHSMCEKEMTMKTC 299

Query: 313 FRY 315
           FRY
Sbjct: 300 FRY 302

gb|EAA65416.1| hypothetical protein AN0774.2 [Aspergillus nidulans FGSC A4]
ref|XP_404911.1| hypothetical protein AN0774.2 [Aspergillus nidulans FGSC A4]
(400 aa)

Score: 201 bits (510), Expect: 3.48887e-50
Length: 366, Idn/Pos/Gap = 135/201/47 (36%/54%/12%)

Query:  26 VLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHES  85
           VL   ++LR+  R V +P+ GEV++ +R  GICGSD+HY+ HG  G F + +PM +GHES
Sbjct:   8 VLHGAKDLRLEPRPVSSPSDGEVQIAIRSTGICGSDLHYYSHGRNGDFVVREPMCLGHES  67

Query:  86 AGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRC--REGRYNLCPNIKFFAT----PPVD 139
           +G+V A+G  V +L+VGDRVALE G+PC +C  C     RYNLCP +KF ++    P +D
Sbjct:  68 SGIVTAIGPNVHNLKVGDRVALEVGLPCRKCALCLSNPSRYNLCPEMKFRSSAKIFPHLD 127

Query: 140 GSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGS----------LV 189
           G+L +   HP   C++LP++VS   GA+ EPL+V +HA RR+     S          L+
Sbjct: 128 GTLMQLTTHPENMCHKLPDTVSYAGGALVEPLAVCLHAIRRSNPPAQSSLPPNYKSTALI 187

Query: 190 LVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGAD-----AVINTRDLDEH 244
              GA  + L   + A+   A  IV+ DIDD RL  A T +  +         +      
Sbjct: 188 FGAGAIGLLLAGALAAQETFAH-IVIADIDDSRLKIASTMSLPNLSTFQIPKPSTPPPPR 246

Query: 245 DAALVVQQ--ALDGAQADIA-------------------LDCAGLESTMRLAMHVVRPGG 283
           DA    Q   AL  AQA  +                    DC G+ + ++  ++   PG 
Sbjct: 247 DAPHAEQTAFALSNAQATASSLKSAISSLDPSGLGFTRVYDCTGVPACVQTGIYAASPGS 306

Query: 284 RICLVGMGSSAMHVPLVDASSREIDIFGVFRYS-NTYPTCIALLASGRVNV--KPLITHR 340
            +  +GMG+    +P+  A+ RE+DI GVFRY  + YP  I L+ASG+++V  K ++THR
Sbjct: 307 VLVQIGMGNPVQTLPVGAAALREVDIIGVFRYDGHAYPAAIELMASGKMDVVEKSVVTHR 366

Query: 341 FMGLEE 346
            +GL++
Sbjct: 367 -LGLQD 371

ref|ZP_00216616.1| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Burkholderia cepacia R18194]
(347 aa)

Score: 198 bits (503), Expect: 2.4788e-49
Length: 337, Idn/Pos/Gap = 124/186/13 (36%/55%/3%)

Query:  24 CGVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGH  83
           C V+  P +LRV  +      PG+VR+ +   GICGSD+HY+ HG  G  RL  PM++GH
Sbjct:   2 CVVIHGPNDLRVEEQDAGEIGPGQVRVDVAMGGICGSDLHYFRHGGFGAIRLQQPMVLGH  61

Query:  84 ESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFAT----PPVD 139
           E AG V  +   VTS++VGDRVA+ P  PC  C+ C EG  N C +++F+ +    P V 
Sbjct:  62 EVAGTVAEVAPDVTSVKVGDRVAVNPSRPCGACRYCLEGLPNQCLDMRFYGSAMRMPHVQ 121

Query: 140 GSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGL 199
           G+    +   A  C ++ + V L   A+ EP +V +HA  RAG  IG  VLV G GPIG+
Sbjct: 122 GAFRNALVCDAVQCVKVADHVPLSLAALAEPFAVGLHAVSRAGPLIGKRVLVSGCGPIGV 181

Query: 200 LNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQA 259
           L    A+  GA+ IV TD+ +  L  A    GAD  IN       DA  V + A D    
Sbjct: 182 LAVAAARVHGAAEIVATDVVEAPLEVASA-LGADRTINAAT----DAGWVERYAADKGTF 236

Query: 260 DIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTY 319
           D+ ++C+G    +R  + V+RP G +  +G+G   + +P     ++E+ I G FR+   +
Sbjct: 237 DVMIECSGNARALRDGLDVMRPRGVVVQLGLGGD-VSLPQNVVVAKELSICGSFRFHAEF 295

Query: 320 PTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETA 356
              + L+ +GRV+++P +T R   + +++L  AFE A
Sbjct: 296 ALAVQLINAGRVDLRPAVT-RVFPMRDANL--AFELA 329

ref|NP_694275.1| alcohol dehydrogenase [Oceanobacillus iheyensis HTE831]
dbj|BAC15309.1| alcohol dehydrogenase [Oceanobacillus iheyensis HTE831]
(351 aa)

Score: 198 bits (503), Expect: 2.52051e-49
Length: 324, Idn/Pos/Gap = 115/185/17 (35%/57%/5%)

Query:  32 ELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDP---------MIIG  82
           ++RV  +  P   PG+V++++   GICGSD+H + HG+ G  ++ +P         + +G
Sbjct:  11 DIRVENKEEPIIKPGKVKIKVAWTGICGSDLHAY-HGAEGVVQVGEPHPVTGEMAPLTLG  69

Query:  83 HESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSL 142
           HE +GV+  +G GV+ L VGDRVA+EP + C +C+ C  G YNLC +  F      DG+ 
Sbjct:  70 HEFSGVIHEIGEGVSGLSVGDRVAIEPAIKCGKCENCVRGNYNLCEHNGFVGLQS-DGAF 128

Query: 143 ARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNC 202
           A Y        ++LP+++S EE    EP +V+ HA + +    G  V V G GPIGL   
Sbjct: 129 AEYAIVDPHMVHKLPDNISFEEATAIEPTAVSFHALKLSNMKAGDTVAVFGVGPIGLTAI 188

Query: 203 MVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIA 262
           + AKA GAS I   D+ + RL  A+   GA  VIN   ++E+ A  +  +   G+   IA
Sbjct: 189 LCAKAAGASRIYAIDVSNERLEMAQK-LGATTVINA--IEENAAEKIYAET--GSGVTIA 243

Query: 263 LDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTC 322
            DCAG E+T+  A+  +  GG++ +V +    + V L+ A+ +EI+I     Y + Y   
Sbjct: 244 FDCAGAEATVNSAIDSLAKGGQLVIVSIIPEPIKVNLLQANLKEINILATIGYRDVYKDV 303

Query: 323 IALLASGRVNVKPLITHRFMGLEE 346
           IA++ SG++++KP+IT + +GL++
Sbjct: 304 IAMVESGQLDLKPIITKK-IGLDD 326

emb|CAF32153.1| zinc-dependent alcohol dehydrogenase, putative [Aspergillus fumigatus]
(400 aa)

Score: 194 bits (493), Expect: 3.34825e-48
Length: 368, Idn/Pos/Gap = 133/195/47 (36%/52%/12%)

Query:  26 VLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHES  85
           VL   ++LR+  R +  P   EV++ +R  G+CGSD+HY+ HG  G F + +PM +GHES
Sbjct:  11 VLHGAKDLRLESRPISPPTGSEVQVAIRATGLCGSDLHYYNHGRNGDFVVREPMCLGHES  70

Query:  86 AGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFAT----PPVDGS 141
           +G V A+G  VT+LQVGDRVALE G+PC  C  CR GRYN+CP++KF ++    P +DG+
Sbjct:  71 SGTVTAVGPDVTTLQVGDRVALEVGLPCRTCTLCRTGRYNICPDMKFRSSAKLFPHLDGT 130

Query: 142 LARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRA--------------GTTIGS 187
           L     HPA  C++LPESVS   GA+ EPL+V +HA RR+              G    +
Sbjct: 131 LMELTNHPADLCHKLPESVSYAGGALVEPLAVCLHAIRRSHPPTPAEVDLATEQGDQTAA 190

Query: 188 LVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFA-------ETH---AGADAVIN 237
           L+   GA  + L   +       S IV+ DID  RL  A       +TH    G +A   
Sbjct: 191 LIFGAGAIGLLLAAALATSQPFTS-IVIADIDPARLEIAKSLNLGLKTHLLPKGGNAANP 249

Query: 238 TRDLDEHDAALVVQQALDGAQADIAL--------------DCAGLESTMRLAMHVVRPGG 283
               D   A        +  +   AL              +C G+ + ++  ++   PG 
Sbjct: 250 PPAPDASAAEHAAYAMQNAQRTAAALKEANGVASGFVRVYECTGVPACVQAGIYAASPGA 309

Query: 284 RICLVGMGSSAMHVPLVDASSREIDIFGVFRY-SNTYPTCIALLASGRVN--VKPLITHR 340
            +  +GMG+    +P+  A+ RE+DI G FRY  + YP  I L+ASG+++   K ++THR
Sbjct: 310 VLVQIGMGNPIQTLPVSAAALREVDIIGTFRYDGHAYPAAIELMASGKLDHVEKQVVTHR 369

Query: 341 FMGLEESS 348
            + LE+ S
Sbjct: 370 -VRLEDGS 376

emb|CAC48827.1| putative alcohol dehydrogenase protein [Sinorhizobium meliloti 1021]
ref|NP_436967.1| putative alcohol dehydrogenase protein [Sinorhizobium meliloti 1021]
pir||C95895 probable alcohol dehydrogenase protein [imported] - Sinorhizobium meliloti (strain 1021) magaplasmid pSymB
(352 aa)

Score: 193 bits (491), Expect: 6.05476e-48
Length: 347, Idn/Pos/Gap = 131/187/14 (37%/53%/4%)

Query:  27 LVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESA  86
           L  PR+LR+ +  VPAP  GEV L+M   GICGSD+HY+  G  GP R+ +P+I GHE++
Sbjct:  13 LYGPRDLRLEVADVPAPGDGEVLLKMAAGGICGSDLHYYQDGGFGPVRVREPIIPGHEAS  72

Query:  87 GVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFAT----PPVDGSL 142
           G V  LGAGV+ L + D VA+ P  PC  C+ C EG    C +++F  +    P   G  
Sbjct:  73 GRVAVLGAGVSGLAIDDLVAVNPSQPCGTCRFCGEGLPVHCLDMRFLGSAMRLPHTQGMF 132

Query: 143 ARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNC 202
             ++  PA  C+     VS  E A  EPL+V +HA  +AG   G  VLV GAGPIG L  
Sbjct: 133 RDWLVVPAVQCHPAGSQVSPGEAACAEPLAVCLHAAAQAGEIRGKKVLVTGAGPIGALVV 192

Query: 203 MVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIA 262
             A+  GA  IVVTD+ D  L  A+   GA  ++N       D A +     D  +  +A
Sbjct: 193 AAARHAGADEIVVTDLADAALDRAKA-MGATRIVNV----HRDPAGLAAYEADKGKFHVA 247

Query: 263 LDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTC 322
            +C+  E  +R A+  VRP G I  VG+ +  + +PL     +E+ + G  R+   +   
Sbjct: 248 FECSAAEPALRGAVAAVRPRGTIVQVGV-TGEITLPLHALVGKELRLVGSQRFDGEFALA 306

Query: 323 IALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLT 369
           +AL++  R++V+P+I+H+F   E      AFE A   +  A KV LT
Sbjct: 307 VALISDRRIDVRPIISHQFPVDEAVR---AFEQAGDRS-AACKVQLT 349

ref|NP_533756.1| zinc-binding dehydrogenase [Agrobacterium tumefaciens str. C58]
gb|AAL44072.1| zinc-binding dehydrogenase [Agrobacterium tumefaciens str. C58]
gb|AAK90134.1| AGR_L_3122p [Agrobacterium tumefaciens str. C58]
pir||D98326 probable zinc-binding alcohol dehydrogenase (D-mannonate hydrolase) [imported] - Agrobacterium tumefaciens (strain C58, Cereon)
pir||AB2957 zinc-binding dehydrogenase Atu3256 [imported] - Agrobacterium tumefaciens (strain C58, Dupont)
ref|NP_357349.1| hypothetical protein AGR_L_3122 [Agrobacterium tumefaciens str. C58]
(348 aa)

Score: 191 bits (486), Expect: 2.45963e-47
Length: 342, Idn/Pos/Gap = 130/182/14 (38%/53%/4%)

Query:  32 ELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEA  91
           ++RV  + V  P PGEV L M   GICGSD+HY+  G  GP R+ +P+I GHE++G + A
Sbjct:  13 DIRVETQDVAPPGPGEVLLAMAAGGICGSDLHYYQDGGFGPVRVREPIICGHEASGHIAA  72

Query:  92 LGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFAT----PPVDGSLARYVC 147
           LGAGV+ L +G  VA+ P  PC  CQ C +G+   C +++F  +    P   G     + 
Sbjct:  73 LGAGVSGLAIGQLVAVNPSQPCGHCQFCLKGQPIHCLDMRFMGSAMRLPHEQGMFRDRLV 132

Query: 148 HPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKA 207
            PA  C    ++ S  E A  EPL+V +HA  +AG   G+ VLV GAGPIGLL    A+ 
Sbjct: 133 VPAKQCATFSDATSPAEAACTEPLAVCLHAVAQAGDLAGAKVLVTGAGPIGLLTIAAARQ 192

Query: 208 FGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAG 267
            GA IIV TD+ D  L  A    GAD  IN     + DA L  Q   +    D+  DC+ 
Sbjct: 193 AGAGIIVATDLTDAALERAPA-MGADRTINVA--KDADALLPYQD--NKGYFDVIFDCSA 247

Query: 268 LESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLA 327
               +R A   VRP G I  VG+ +  + +PL     +EI   G  R+ + +     L++
Sbjct: 248 AGPALRSAFACVRPRGTIVQVGV-TGDVTIPLNALVGKEIVWRGSQRFHDEFAIAAGLIS 306

Query: 328 SGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLT 369
           S +++V+P+I+H F        +AAFE A   +  A KV LT
Sbjct: 307 SRKIDVRPIISHSF---PLGDAKAAFEQAGDRS-AACKVQLT 344

ref|NP_142610.1| dehydrogenase [Pyrococcus horikoshii OT3]
dbj|BAA29746.1| 348aa long hypothetical dehydrogenase [Pyrococcus horikoshii OT3]
sp|O58389|TDH_PYRHO Probable L-threonine 3-dehydrogenase
(348 aa)

Score: 188 bits (478), Expect: 2.15286e-46
Length: 332, Idn/Pos/Gap = 118/172/11 (35%/51%/3%)

Query:  40 VPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSL  99
           VP P PGEV +++    ICG+D+H +        R+  P I+GHE AG V  +G GV  +
Sbjct:  24 VPKPGPGEVLIKVLATSICGTDLHIYEWNEWAQSRIKPPQIMGHEVAGEVVEIGPGVEGI  83

Query: 100 QVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPES 159
           +VGD V++E  + C +C  CR G+Y++C N K F     DG  A Y   PA   ++ P+S
Sbjct:  84 EVGDYVSVETHIVCGKCYACRRGQYHVCQNTKIFGV-DTDGVFAEYAVVPAQNIWKNPKS 142

Query: 160 VSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDID 219
           +  E   + EPL  AV     AG   G  VL+ GAGP+GLL   VAKA GA  ++V++  
Sbjct: 143 IPPEYATLQEPLGNAVD-TVLAGPISGKSVLITGAGPLGLLGIAVAKASGAYPVIVSEPS 201

Query: 220 DRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVV 279
           D R   A+   GAD VIN     E D    V    DG   D+ L+ +G    +   +  V
Sbjct: 202 DFRRELAKK-VGADYVINPF---EEDVVKEVMDITDGNGVDVFLEFSGAPKALEQGLQAV 257

Query: 280 RPGGRICLVGMGSSAMHVPLVD-ASSREIDIFGVF--RYSNTYPTCIALLASGRVNVKPL 336
            P GR+ L+G+    + +   +    + + I+G+       T+ T   LL SG++N+ P+
Sbjct: 258 TPAGRVSLLGLYPGKVTIDFNNLIIFKALTIYGITGRHLWETWYTVSRLLQSGKLNLDPI 317

Query: 337 ITHRFMGLEESSLEAAFETARTAANGAVKVML 368
           ITH++ G ++   E AFE  R    G V  ML
Sbjct: 318 ITHKYKGFDK--YEEAFELMRAGKTGKVVFML 347

emb|CAB50292.1| tdh threonine 3-dehydrogenase (EC 1.1.1.103) [Pyrococcus abyssi GE5]
ref|NP_127062.1| threonine 3-dehydrogenase [Pyrococcus abyssi GE5]
sp|Q9UYX0|TDH_PYRAB Probable L-threonine 3-dehydrogenase
pir||G75049 L-threonine 3-dehydrogenase (EC 1.1.1.103) PAB2382 - Pyrococcus abyssi (strain Orsay)
(348 aa)

Score: 187 bits (474), Expect: 5.2571e-46
Length: 332, Idn/Pos/Gap = 117/172/11 (35%/51%/3%)

Query:  40 VPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSL  99
           VP P PGEV +++    ICG+D+H +        R+  P I+GHE AG V  +G GV  +
Sbjct:  24 VPKPGPGEVLIKVIATSICGTDLHIYEWNEWAQSRIKPPQIMGHEVAGEVVEVGPGVEGI  83

Query: 100 QVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPES 159
           +VGD V++E  + C +C  CR G+Y++C N K F     DG  A Y   PA   ++ P+S
Sbjct:  84 EVGDYVSVETHIVCGKCYACRRGQYHVCQNTKIFGV-DTDGVFAEYAVVPAQNVWKNPKS 142

Query: 160 VSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDID 219
           +  E   + EPL  AV     AG   G  VL+ GAGP+GLL   VAKA GA  ++V++  
Sbjct: 143 IPPEYATLQEPLGNAVD-TVLAGPISGKSVLITGAGPLGLLGIAVAKASGAYPVIVSEPS 201

Query: 220 DRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVV 279
           D R   A+   GAD VIN     E D    V    DG   D+ L+ +G    +   +  V
Sbjct: 202 DFRRELAKK-VGADYVINPF---EEDVVKEVMDITDGNGVDVFLEFSGAPKALEQGLQAV 257

Query: 280 RPGGRICLVGMGSSAMHVPLVD-ASSREIDIFGVF--RYSNTYPTCIALLASGRVNVKPL 336
            P GR+ L+G+    + +   +    + + ++G+       T+ T   LL SG++N+ P+
Sbjct: 258 TPAGRVSLLGLYPGKVSIDFNNLIIFKALTVYGITGRHLWETWYTVSRLLQSGKLNLDPI 317

Query: 337 ITHRFMGLEESSLEAAFETARTAANGAVKVML 368
           ITH++ G ++   E AFE  R    G V  ML
Sbjct: 318 ITHKYKGFDK--YEEAFELMRAGKTGKVVFML 347

gb|AAV95678.1| L-idonate 5-dehydrogenase [Silicibacter pomeroyi DSS-3]
ref|YP_167641.1| L-idonate 5-dehydrogenase [Silicibacter pomeroyi DSS-3]
(349 aa)

Score: 186 bits (472), Expect: 9.0424e-46
Length: 349, Idn/Pos/Gap = 128/187/19 (36%/53%/5%)

Query:  31 RELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVE  90
           R++RV    +P P P +V + M   GICGSD+HY+  G  GP R+ +PMI+GHE AGVV 
Sbjct:  12 RDIRVETDPLPEPGPAQVIVAMAAAGICGSDLHYYHDGGFGPIRVREPMILGHEGAGVVA  71

Query:  91 ALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFAT----PPVDGSLARYV 146
           ALG GVT L VGDRVA+ P  PC  C  C EG    C N++F+ +    P   G     +
Sbjct:  72 ALGPGVTGLAVGDRVAVNPSRPCGTCSYCVEGLTTHCLNMRFYGSAMRFPHEQGLFRDKL 131

Query: 147 CHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAK 206
              AA C++L + V++ EGA  EPL+V +HA   AG   G  VLV G+GPIG+L   VA 
Sbjct: 132 LTDAAQCHKLSDHVTISEGACAEPLAVCLHARHMAGEVRGKRVLVTGSGPIGVLCAAVAA 191

Query: 207 AFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCA 266
             GA+ IVVTD+ D  L  A        V   R+++   A      A+D    D+  +C+
Sbjct: 192 EAGAAEIVVTDLQDAPLEVARRMGATRTVNIAREVEAMAA-----YAVDKGHFDLVFECS 246

Query: 267 GLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRY-SNTYPTCIAL 325
                +  A+  +RP G    VG+ +  + +P+     +E+ + G  R+ +  +   + L
Sbjct: 247 AAAPAIHSAIAALRPQGTYVQVGV-TGDVPLPVNLIVGKELCLQGTQRFRAEEFAEAVRL 305

Query: 326 LASGRVNVKPLITHRFMGLEESSLEAAFETARTAAN--GAVKVMLTIPE 372
           ++S R++++ +I+  F       LE A E  R AA+   AVKV LT  +
Sbjct: 306 ISSRRIDLRAMISGSF------PLEQAEEAFRMAADRSRAVKVHLTFAD 348

ref|NP_354415.1| hypothetical protein AGR_C_2601 [Agrobacterium tumefaciens str. C58]
gb|AAK87200.1| AGR_C_2601p [Agrobacterium tumefaciens str. C58]
pir||G97530 probable zinc-binding alcohol dehydrogenase [imported] - Agrobacterium tumefaciens (strain C58, Cereon)
(371 aa)

Score: 186 bits (472), Expect: 9.99464e-46
Length: 332, Idn/Pos/Gap = 115/187/11 (34%/56%/3%)

Query:  12 DAGSVLNEKANPCGVLVRP-RELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSC  70
           DA     E+    GV++   ++LRV   +    A  EVR+ +   GICGSD+HY+ HG  
Sbjct:  14 DANRNWREETRMRGVVIHAAKDLRVEDVAGQPLAADEVRVAVAVGGICGSDLHYYNHGGF  73

Query:  71 GPFRLHDPMIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNI 130
           G  R+ +PM +GHE AG V  +G+ V+ L  G RVA+ P +PC  C+ C +GR N C ++
Sbjct:  74 GTVRVREPMALGHEFAGTVVEVGSSVSHLVPGMRVAVNPSLPCGTCRYCAQGRQNQCLDM 133

Query: 131 KFFA----TPPVDGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIG 186
           +F      +P V G     V   +    ++ + +S+ E AM EPL+V +HA R+AG+ +G
Sbjct: 134 RFMGSAMRSPHVQGGFREVVTVHSTQPVQIADGLSMGEAAMAEPLAVCLHAARQAGSLLG 193

Query: 187 SLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDA 246
             VL+ GAGPIG+L+ +VA+  GA+ IVVTD+ D  L  A    GAD  +N       DA
Sbjct: 194 KTVLITGAGPIGMLSLLVARLAGAAHIVVTDVADAPLDLAR-RIGADEAVNIL----RDA 248

Query: 247 ALVVQQALDGAQADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSRE 306
            ++ +   +    D+  + +G ++ +  A+ ++RPGG I  +G+G     +P+    ++E
Sbjct: 249 DMLEKYRFEKGVFDVLFEASGNQAALLPALDLLRPGGIIVQLGLGGD-FTIPMNLIVAKE 307

Query: 307 IDIFGVFRYSNTYPTCIALLASGRVNVKPLIT 338
           + + G FR+   +   + ++  G ++VKPLI+
Sbjct: 308 LQLRGTFRFHEEFAQAVNMMGRGLIDVKPLIS 339

ref|NP_532098.1| sorbitol dehydrogenase [Agrobacterium tumefaciens str. C58]
gb|AAL42414.1| sorbitol dehydrogenase [Agrobacterium tumefaciens str. C58]
pir||AH2749 sorbitol dehydrogenase gutB [imported] - Agrobacterium tumefaciens (strain C58, Dupont)
(347 aa)

Score: 184 bits (468), Expect: 2.52343e-45
Length: 312, Idn/Pos/Gap = 110/179/10 (35%/57%/3%)

Query:  31 RELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVE  90
           ++LRV   +    A  EVR+ +   GICGSD+HY+ HG  G  R+ +PM +GHE AG V 
Sbjct:  10 KDLRVEDVAGQPLAADEVRVAVAVGGICGSDLHYYNHGGFGTVRVREPMALGHEFAGTVV  69

Query:  91 ALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFA----TPPVDGSLARYV 146
            +G+ V+ L  G RVA+ P +PC  C+ C +GR N C +++F      +P V G     V
Sbjct:  70 EVGSSVSHLVPGMRVAVNPSLPCGTCRYCAQGRQNQCLDMRFMGSAMRSPHVQGGFREVV 129

Query: 147 CHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAK 206
              +    ++ + +S+ E AM EPL+V +HA R+AG+ +G  VL+ GAGPIG+L+ +VA+
Sbjct: 130 TVHSTQPVQIADGLSMGEAAMAEPLAVCLHAARQAGSLLGKTVLITGAGPIGMLSLLVAR 189

Query: 207 AFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCA 266
             GA+ IVVTD+ D  L  A    GAD  +N       DA ++ +   +    D+  + +
Sbjct: 190 LAGAAHIVVTDVADAPLDLAR-RIGADEAVNIL----RDADMLEKYRFEKGVFDVLFEAS 244

Query: 267 GLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALL 326
           G ++ +  A+ ++RPGG I  +G+G     +P+    ++E+ + G FR+   +   + ++
Sbjct: 245 GNQAALLPALDLLRPGGIIVQLGLGGD-FTIPMNLIVAKELQLRGTFRFHEEFAQAVNMM 303

Query: 327 ASGRVNVKPLIT 338
             G ++VKPLI+
Sbjct: 304 GRGLIDVKPLIS 315

ref|NP_578720.1| possible threonine 3-dehydrogenase [Pyrococcus furiosus DSM 3638]
gb|AAL81115.1| possible threonine 3-dehydrogenase [Pyrococcus furiosus DSM 3638]
sp|Q8U259|TDH_PYRFU Probable L-threonine 3-dehydrogenase
(348 aa)

Score: 184 bits (468), Expect: 2.58739e-45
Length: 332, Idn/Pos/Gap = 114/172/11 (34%/51%/3%)

Query:  40 VPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSL  99
           VP P PGEV +++    ICG+D+H +        R+  P I+GHE AG V  +G GV  +
Sbjct:  24 VPKPGPGEVLIKILATSICGTDLHIYEWNEWAQTRIRPPQIMGHEVAGEVVEVGPGVEGI  83

Query: 100 QVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPES 159
           +VGD V++E  + C +C  C+ G+Y++C N K F     DG  A Y   PA   ++ P++
Sbjct:  84 EVGDYVSVETHIVCGKCYACKRGQYHVCQNTKIFGV-DTDGVFAEYAVVPAQNVWKNPKN 142

Query: 160 VSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDID 219
           +  E   + EPL  AV     AG   G  VL+ GAGP+GLL   VAKA GA  ++V++  
Sbjct: 143 IPPEYATLQEPLGNAVD-TVLAGPIAGKSVLITGAGPLGLLGIAVAKASGAYPVIVSEPS 201

Query: 220 DRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVV 279
           + R   A+   GAD VIN     E D    V    DG   D+ L+ +G    +   +  V
Sbjct: 202 EFRRNLAKK-VGADYVINPF---EEDVVKEVMDITDGNGVDVFLEFSGAPKALEQGLQAV 257

Query: 280 RPGGRICLVGMGSSAMHVPLVD-ASSREIDIFGVF--RYSNTYPTCIALLASGRVNVKPL 336
            P GR+ L+G+    + +   +    + + ++G+       T+ T   LL SG++N+ P+
Sbjct: 258 TPAGRVSLLGLFPGKVSIDFNNLIIFKALTVYGITGRHLWETWYTVSRLLQSGKLNIDPI 317

Query: 337 ITHRFMGLEESSLEAAFETARTAANGAVKVML 368
           ITH++ G ++   E AFE  R    G V  ML
Sbjct: 318 ITHKYKGFDK--YEEAFELMRAGKTGKVVFML 347

dbj|BAA15565.1| Sorbitol dehydrogenase (EC 1.1.1.14) (L-iditol 2-dehydrogenase). [Escherichia coli]
(263 aa)

Score: 184 bits (468), Expect: 2.69762e-45
Length: 268, Idn/Pos/Gap = 104/156/11 (38%/58%/4%)

Query: 103 DRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPP-VDGSLARYVCHPAAWCYRLPESVS 161
           DRV +EPGVPC  C+ C EG+YN+CP++ F AT P   G+L  Y+CHP ++ Y+LP+++ 
Sbjct:   1 DRVNIEPGVPCGHCRYCLEGKYNICPDVDFMATQPNYRGALTHYLCHPESFTYKLPDNMD  60

Query: 162 LEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDR 221
             EGA+ EP +V +HA   A    G  +++LGAG IGL+     K  GA+ I V D+ ++
Sbjct:  61 TMEGALVEPAAVGMHAAMLADVKPGKKIIILGAGCIGLMTLQACKCLGATEIAVVDVLEK 120

Query: 222 RLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVVRP 281
           RLA AE   GA  VIN     + D     QQ  +   ADI  + AG   T++ A ++V  
Sbjct: 121 RLAMAE-QLGATVVINGA---KEDTIARCQQFTEDMGADIVFETAGSAVTVKQAPYLVMR 176

Query: 282 GGRICLVGM--GSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASGRVNVKPLITH 339
           GG+I +VG   G SA++   ++   RE+ I  VFRY+N YP  I  ++SGR +VK ++TH
Sbjct: 177 GGKIMIVGTVPGDSAINFLKIN---REVTIQTVFRYANRYPVTIEAISSGRFDVKSMVTH 233

Query: 340 RFMGLE-ESSLEAAFETARTAANGAVKV 366
            +   + + + E +    R    G +K+
Sbjct: 234 IYDYRDVQQAFEESVNNKRDIIKGVIKI 261

ref|YP_004176.1| threonine 3-dehydrogenase [Thermus thermophilus HB27]
gb|AAS80549.1| threonine 3-dehydrogenase [Thermus thermophilus HB27]
(343 aa)

Score: 184 bits (467), Expect: 3.89423e-45
Length: 343, Idn/Pos/Gap = 129/183/16 (37%/53%/4%)

Query:  30 PRE-LRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGV  88
           P E L ++ R VP P PGE+ +++    ICG+D+H W   +    R+  P++ GHE +GV
Sbjct:   9 PEEGLTLVDRPVPEPGPGEILVRVEAASICGTDLHIWKWDAWARGRIRPPLVTGHEFSGV  68

Query:  89 VEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCH 148
           VEA+G GV   QVGD V+LE  V C  C  CR G Y++C N K       DG  A YV  
Sbjct:  69 VEAVGPGVKRPQVGDHVSLESHVVCHACPACRTGNYHVCLNTKILGVDR-DGGFAEYVVV 127

Query: 149 PAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAF 208
           PA   +  P+ +  E  A+ EP   AVH         G  VL+ GAGPIGL+  MVA+A 
Sbjct: 128 PAENAWVNPKDLPFEVAAILEPFGNAVHTVYAGSGVSGKSVLITGAGPIGLMAAMVARAS 187

Query: 209 GASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGL 268
           GA  I+V+D +  RLAFA  +  AD ++N  + D     L V + + G+  ++ L+ +G 
Sbjct: 188 GAGPILVSDPNPYRLAFARPY--ADRLVNPLEED----LLEVVRRVTGSGVEVLLEFSGN 241

Query: 269 ESTMRLAMHVVRPGGRICLVGMGSSAMHVPLV-DASSREIDIFGVF--RYSNTYPTCIAL 325
           E+ +   +  + PGG   ++G+ S  +   L  +   R I  FG+   R   T+    AL
Sbjct: 242 EAAIHQGLMALIPGGEARILGIPSDPIRFDLAGELVMRGITAFGIAGRRLWQTWMQGTAL 301

Query: 326 LASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVML 368
           + SGRV++ PLITHR   L  S    AF     A+  AVKV+L
Sbjct: 302 VYSGRVDLSPLITHR---LPLSRYREAF--GLLASGQAVKVIL 339

emb|CAD74526.1| probable alcohol dehydrogenase (Zn-dependent) [Rhodopirellula baltica SH 1]
ref|NP_866984.1| probable alcohol dehydrogenase (Zn-dependent) [Rhodopirellula baltica SH 1]
(346 aa)

Score: 183 bits (465), Expect: 6.31819e-45
Length: 319, Idn/Pos/Gap = 117/172/11 (36%/53%/3%)

Query:  26 VLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHES  85
           +L   + ++V     P   P +V +Q+   GICGSD+H  + GS G  R   P+++GHE+
Sbjct:   5 LLTEYKNMQVTDVDEPEVGPDDVLVQVEACGICGSDIH-GYDGSTG--RRIPPLVMGHEA  61

Query:  86 AGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVD----GS 141
           AGVV  +G  V  L++G RV  +  V C  C+ CREG  NLC N         D    G+
Sbjct:  62 AGVVVQVGENVRDLELGARVTFDSMVSCGNCEFCREGHGNLCDNRMVLGVSCGDYRRHGA 121

Query: 142 LARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLN 201
            A  +  P    YRLP+++  E  A+ E +SVAVHA       +G   +V+GAG IGLL 
Sbjct: 122 FAERISVPRRIVYRLPDTLPFEHAALVEAVSVAVHAAEVTPIKLGDTAVVVGAGMIGLLA 181

Query: 202 CMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADI 261
               +A GA+ ++  D++D+RL  A T  GAD ++     D+ D    V++   G  AD+
Sbjct: 182 VQAVRAAGATQVIAVDLNDKRLETAGT-LGADVLLRA---DQVDVPEKVRELTGGRGADV 237

Query: 262 ALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPT 321
           AL+  G   T++ A+  VR GG + LVG  S  + +PL    +REI + G    +  YP 
Sbjct: 238 ALEVVGATPTVKTAIESVRKGGAVTLVGNVSPTIELPLQSVVTREIRLQGTCGCNGEYPQ 297

Query: 322 CIALLASGRVNVKPLITHR 340
           CI L+  G +NV+PLIT +
Sbjct: 298 CIDLMNRGVINVEPLITAK 316

dbj|BAD85105.1| threonine 3-dehydrogenase [Thermococcus kodakaraensis KOD1]
ref|YP_183329.1| threonine 3-dehydrogenase [Thermococcus kodakaraensis KOD1]
(350 aa)

Score: 182 bits (463), Expect: 1.16177e-44
Length: 328, Idn/Pos/Gap = 113/170/11 (34%/51%/3%)

Query:  40 VPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSL  99
           VP P PGEV +++    ICG+D+H +        R+  P I+GHE AG V  +G GV  L
Sbjct:  24 VPKPGPGEVLIKVLATSICGTDLHIYEWNEWAQSRIKPPQIMGHEVAGEVVEVGPGVEDL  83

Query: 100 QVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPES 159
           QVGD +++E  + C +C  C+  RY++C N K F    +DG  A Y   PA   ++ P+ 
Sbjct:  84 QVGDYISVETHIVCGKCYACKHNRYHVCQNTKIFGV-DMDGVFAHYAIVPAKNAWKNPKD 142

Query: 160 VSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDID 219
           +  E  A+ EPL  AV     AG   G   L+ GAGP+GLL   VAKA GA  ++V++  
Sbjct: 143 MPPEYAALQEPLGNAVD-TVLAGPIAGRSTLITGAGPLGLLGIAVAKASGAYPVIVSEPS 201

Query: 220 DRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVV 279
           + R   A+   GAD V+N     E D    V    DGA  ++ L+ +G    +   +  V
Sbjct: 202 EFRRKLAKK-VGADYVVNPF---EEDPVKFVMDITDGAGVEVFLEFSGAPKALEQGLKAV 257

Query: 280 RPGGRICLVGMGSSAMHVP---LVDASSREIDIFGVFRYSNTYPTCIALLASGRVNVKPL 336
            PGGR+ L+G+    + +    L+   + E+          T+ T  +L+ SG++N+ P+
Sbjct: 258 TPGGRVSLLGLFPREVTIDFNNLIIFKALEVHGITGRHLWETWYTVSSLIQSGKLNLDPI 317

Query: 337 ITHRFMGLEESSLEAAFETARTAANGAV 364
           ITH++ G ++   E AFE  R    G V
Sbjct: 318 ITHKYKGFDK--FEEAFELMRAGKTGKV 343

ref|XP_544659.1| PREDICTED: similar to Sorbitol dehydrogenase (L-iditol 2-dehydrogenase) [Canis familiaris]
(557 aa)

Score: 182 bits (462), Expect: 1.36134e-44
Length: 214, Idn/Pos/Gap = 106/143/7 (49%/66%/3%)

Query: 155 RLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIV 214
           +LP++V+ EEGA+ EPLSV +HA RRAG T+G+ VLV GAGPIGL+  +VAKA GA  ++
Sbjct: 342 KLPDNVTYEEGALIEPLSVGIHACRRAGITLGNKVLVCGAGPIGLVTLIVAKAMGAGQVL 401

Query: 215 VTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRL 274
           VTD+   RL+ A+   GAD V+        + A  V+  L G + +  ++C G+ES ++ 
Sbjct: 402 VTDLSASRLSKAK-EVGADIVLQISKESPKEIASKVEDML-GCKPEATIECTGVESAIQS 459

Query: 275 AMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASGRVNVK 334
            ++  R GG + LVG+GS    VPL  AS+RE+DI GVFRY NT+P  I++LAS  VNVK
Sbjct: 460 GIYATRAGGTLVLVGLGSEMTTVPLTHASTREVDIKGVFRYCNTWPMAISMLASKAVNVK 519

Query: 335 PLITHRFMGLEESSLEAAFETARTAANGAVKVML 368
           PL+THRF    E +LE AFETAR      +KVML
Sbjct: 520 PLVTHRFP--LEKALE-AFETARKGT--GLKVML 548


Score: 128 bits (322), Expect: 2.57857e-28
Length: 117, Idn/Pos/Gap = 60/80/0 (51%/68%/0%)

Query:  40 VPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSL  99
           +P P P EV L+M  VGICGSDVHYW HG  G F +  PM++GHE++G V  +G+ V  L
Sbjct: 167 IPEPGPNEVLLKMHSVGICGSDVHYWQHGRIGDFIVKKPMVLGHEASGTVVKVGSLVKHL 226

Query: 100 QVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRL 156
           + GDRVA+EPG      + C+ GRYNL P+I F ATPP DG+L ++  H A +CY++
Sbjct: 227 KSGDRVAIEPGALREMDEFCKIGRYNLSPSIFFCATPPDDGNLCQFYKHNADFCYKV 283

ref|ZP_00137552.1| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Pseudomonas aeruginosa UCBPP-PA14]
(352 aa)

Score: 182 bits (462), Expect: 1.56881e-44
Length: 332, Idn/Pos/Gap = 125/178/19 (37%/53%/5%)

Query:  31 RELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHG--SCGPFRLHD------PMIIG  82
           R+LR+      AP PGEV L++   GICGSD+H +  G  S      H       P+ +G
Sbjct:  10 RDLRLSELERQAPRPGEVELEVAYCGICGSDLHEYQSGPHSIPQAEAHPLSGCRAPLTLG  69

Query:  83 HESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSL 142
           HE  GVV ALG GV  L++GDRVA+EP   C +C+ CREGRYNLC ++ F      DG  
Sbjct:  70 HEFCGVVAALGPGVEGLRIGDRVAVEPEYRCGECRYCREGRYNLCESMGFIGLMG-DGGF 128

Query: 143 ARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNC 202
           A     PA   +RLP++V   + A+ EP +VA+HA RR+    G    V G GPIGLL  
Sbjct: 129 AERARVPAYMLHRLPDAVGFRQAAVLEPAAVALHALRRSSLAPGQRCAVFGLGPIGLLLV 188

Query: 203 MVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIA 262
           M+A+  G   I   D+   RLA A    GA   ++ RD D         +  +G   D A
Sbjct: 189 MLARLRGIEDIAAVDVSPERLALA-GEFGASRALDARDGD------TAARLREGGALDCA 241

Query: 263 LDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTC 322
            + AG ++++  A+  +R GG + LV +    + +   D  +RE+ + G   Y + YP  
Sbjct: 242 FEAAGSQASLDAALASLRKGGELVLVSL-MGEVRLDAFDLVNRELRLLGSVGYRDAYPEL 300

Query: 323 IALLASGRVNVKPLITHRFMGLEESSLEAAFE 354
           IALLA GR+++   +T R + LE+ ++E  FE
Sbjct: 301 IALLADGRLDLARAVT-RSVPLEQ-AVEHGFE 330

ref|ZP_00218217.1| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Burkholderia cepacia R18194]
(359 aa)

Score: 182 bits (461), Expect: 1.64935e-44
Length: 315, Idn/Pos/Gap = 121/171/12 (38%/54%/3%)

Query:  41 PAPAPGEVRLQMRCVGICGSDVHYWWHG-------SCGPF-RLHDPMIIGHESAGVVEAL  92
           P   PG+VR+ +   GICGSD+H +  G       +  P  R   P+ +GHE  G V  +
Sbjct:   6 PRVGPGDVRIAVAYCGICGSDLHEYADGPHAIPVDTPHPLSRRTAPLTLGHEFCGTVVEV  65

Query:  93 GAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAW 152
           G GVT+L+ GDRVA+EP   C QC  CR G YNLC ++ F A    DG +A +   PA  
Sbjct:  66 GEGVTALRAGDRVAVEPEYRCSQCAYCRSGSYNLCVSMGF-AGLMGDGGMADFAVVPAYM 124

Query: 153 CYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASI 212
            +RLP+ VSLE+ A+ EP +VA+HA RR    +G    V G GPIGLL  M+AK  GA+ 
Sbjct: 125 LHRLPDGVSLEQAAVMEPAAVALHALRRGELRLGETCAVFGLGPIGLLLIMLAKLQGATT 184

Query: 213 IVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTM 272
           IV  D+   RLA A T  GA    + R L        ++ A  G   D + + AGL++T 
Sbjct: 185 IVAVDVSPERLA-AATRFGATHTFDARALGASALQDAIRAATGGLGVDASFEAAGLQTTF 243

Query: 273 RLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASGRVN 332
             AMH +R GGRI +VG+   A       A + E+       Y + Y   + ++ASG ++
Sbjct: 244 ESAMHALRKGGRIVMVGLMPHA-GFDAFRAVNDELTFTASVGYRHAYEDLLRIVASGALD 302

Query: 333 VKPLITHRFMGLEES 347
           +  ++T R + LE++
Sbjct: 303 LTSIVT-RTVSLEDA 316

ref|NP_773471.1| L-idonate 5-dehydrogenase [Bradyrhizobium japonicum USDA 110]
dbj|BAC52096.1| L-idonate 5-dehydrogenase [Bradyrhizobium japonicum USDA 110]
(349 aa)

Score: 181 bits (460), Expect: 2.3221e-44
Length: 352, Idn/Pos/Gap = 126/183/19 (35%/51%/5%)

Query:  25 GVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHE  84
             L  P +LR++   +   A G VR++    GICGSD+HY+ H   G F +  P+++GHE
Sbjct:   8 ATLFGPEDLRMIEHPLDKLASGMVRIRFGAGGICGSDMHYFRHARTGDFVVKSPLVLGHE  67

Query:  85 SAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFA----TPPVDG 140
            +G V  +     +L+VGDRVA+ P   C  C  CREGR NLC NI F      TP + G
Sbjct:  68 ISGEVVEISGSAANLKVGDRVAVNPSRWCGHCVACREGRPNLCENIYFMGSASKTPHMQG 127

Query: 141 SLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLL 200
             A Y     A C ++P+ VS +  A+ EPL+V +HA  RAG   G   ++ GAGPIGLL
Sbjct: 128 GFANYFDAIPAQCVKIPDHVSYQAAALAEPLAVCLHAVARAGNIEGKRGIIFGAGPIGLL 187

Query: 201 NCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQAD 260
             + A   G + I V DI    LAFA +  GA  V N    +E    L  Q A      D
Sbjct: 188 TMLAAHRAGMADITVADIAPAPLAFA-SRLGASHVENVSGGEE---GLKAQAA--ARPYD 241

Query: 261 IALDCAGLESTMRLAMHVVRPGGRICLVG-MGSSAMHVPLVDASSREIDIFGVFRYSNTY 319
           +A + +G  + +  A+ +VR GG +  +G +    +  P     ++EID+ G FR+   +
Sbjct: 242 VAFEVSGTAAGLASAIGIVRRGGVVVQIGNLPGGQIPTPSNAVMAKEIDLRGSFRFGFEF 301

Query: 320 PTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAAN--GAVKVMLT 369
            T + L+++G V+V  L+T       E  L  A +  R A +   +VKV+LT
Sbjct: 302 MTAVELISAGSVDVLSLVT------AERPLSTAPDALRLALDRSQSVKVVLT 347

ref|YP_143835.1| threonine 3-dehydrogenase [Thermus thermophilus HB8]
dbj|BAD70392.1| threonine 3-dehydrogenase [Thermus thermophilus HB8]
(343 aa)

Score: 179 bits (455), Expect: 9.43308e-44
Length: 343, Idn/Pos/Gap = 125/182/16 (36%/53%/4%)

Query:  30 PRE-LRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGV  88
           P E L ++ R VP P PGE+ +++    ICG+D+H W   +    R+  P++ GHE +GV
Sbjct:   9 PEEGLTLVDRPVPEPGPGEILVRVEAASICGTDLHIWKWDAWARGRIRPPLVTGHEFSGV  68

Query:  89 VEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCH 148
           VEA+G GV   QVGD V+LE  + C  C  CR G Y++C N +       DG  A YV  
Sbjct:  69 VEAVGPGVRRPQVGDHVSLESHIVCHACPACRTGNYHVCLNTQILGVDR-DGGFAEYVVV 127

Query: 149 PAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAF 208
           PA   +  P+ +  E  A+ EP   AVH         G  VL+ GAGPIGL+  MV +A 
Sbjct: 128 PAENAWVNPKDLPFEVAAILEPFGNAVHTVYAGSGVSGKSVLITGAGPIGLMAAMVVRAS 187

Query: 209 GASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGL 268
           GA  I+V+D +  RLAFA  +  AD ++N  + D     L V + + G+  ++ L+ +G 
Sbjct: 188 GAGPILVSDPNPYRLAFARPY--ADRLVNPLEED----LLEVVRRVTGSGVEVLLEFSGN 241

Query: 269 ESTMRLAMHVVRPGGRICLVGMGSSAMHVPLV-DASSREIDIFGVF--RYSNTYPTCIAL 325
           E+ +   +  + PGG   ++G+ S  +   L  +   R I  FG+   R   T+    AL
Sbjct: 242 EAAIHQGLMALIPGGEARILGIPSDPIRFDLAGELVMRGITAFGIAGRRLWQTWMQGTAL 301

Query: 326 LASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVML 368
           + SGRV++ PL+THR   L  S    AF     A+  AVKV+L
Sbjct: 302 VYSGRVDLSPLLTHR---LPLSRYREAF--GLLASGQAVKVIL 339

ref|NP_252786.1| probable alcohol dehydrogenase (Zn-dependent) [Pseudomonas aeruginosa PAO1]
gb|AAG07484.1| probable alcohol dehydrogenase (Zn-dependent) [Pseudomonas aeruginosa PAO1]
pir||B83133 probable alcohol dehydrogenase (Zn-dependent) PA4097 [imported] - Pseudomonas aeruginosa (strain PAO1)
(352 aa)

Score: 179 bits (455), Expect: 9.67218e-44
Length: 332, Idn/Pos/Gap = 124/177/19 (37%/53%/5%)

Query:  31 RELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHG--SCGPFRLHD------PMIIG  82
           R+LR+      AP PGEV L++   GICGSD+H +  G  S      H       P+ +G
Sbjct:  10 RDLRLSELERQAPRPGEVELEVAYCGICGSDLHEYQSGPHSIPQAEAHPLSGCRAPLTLG  69

Query:  83 HESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSL 142
           HE  GVV ALG GV   ++GDRVA+EP   C +C+ CREGRYNLC ++ F      DG  
Sbjct:  70 HEFCGVVAALGPGVEGPRIGDRVAVEPEYRCGECRYCREGRYNLCESMGFIGLMG-DGGF 128

Query: 143 ARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNC 202
           A     PA   +RLP++V   + A+ EP +VA+HA RR+    G    V G GPIGLL  
Sbjct: 129 AERARVPAYMLHRLPDAVGFRQAAVLEPAAVALHALRRSSLAPGQRCAVFGLGPIGLLLV 188

Query: 203 MVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIA 262
           M+A+  G   I   D+   RLA A    GA   ++ RD D         +  +G   D A
Sbjct: 189 MLARLRGIEDIAAVDVSPERLALA-GEFGASRALDARDGD------TAARLREGGALDCA 241

Query: 263 LDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTC 322
            + AG ++++  A+  +R GG + LV +    + +   D  +RE+ + G   Y + YP  
Sbjct: 242 FEAAGSQASLDAALASLRKGGELVLVSL-MGEVRLDAFDLVNRELRLLGSVGYRDAYPEL 300

Query: 323 IALLASGRVNVKPLITHRFMGLEESSLEAAFE 354
           IALLA GR+++   +T R + LE+ ++E  FE
Sbjct: 301 IALLADGRLDLARAVT-RSVPLEQ-AVEHGFE 330

ref|NP_742715.1| 2,3-butanediol dehydrogenase [Pseudomonas putida KT2440]
gb|AAN66179.1| 2,3-butanediol dehydrogenase [Pseudomonas putida KT2440]
(362 aa)

Score: 178 bits (452), Expect: 2.26535e-43
Length: 347, Idn/Pos/Gap = 120/184/16 (34%/53%/4%)

Query:  32 ELRVMLRSVPA-PAPGEVRLQMRCVGICGSDVHYWWHGSCG-PFRLHDPM-------IIG  82
           ++RV    +PA PAPG V++++   GICGSD+H +  G    P     P+       I+G
Sbjct:  19 DIRVEQVPLPADPAPGWVQIKVDWCGICGSDLHEYVAGPVFIPVEAPHPLTGIQGQCILG  78

Query:  83 HESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSL 142
           HE  G +  LG GV    VGD VA +    C  C  C  G YN+C  + F      +G+ 
Sbjct:  79 HEFCGHIAKLGEGVEGYAVGDPVAADACQHCGTCYYCTHGLYNICERLAFTGLMN-NGAF 137

Query: 143 ARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNC 202
           A  V  PA   YRLP+    E GA+ EPL+V +HA ++AG+ +G  V+V+GAG IGL   
Sbjct: 138 AELVNVPANLLYRLPQGFPAEAGALIEPLAVGMHAVKKAGSLLGQTVVVVGAGTIGLCTI 197

Query: 203 MVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIA 262
           M AKA GA+ ++  ++   R A A+  AGA+ V+   D  + DA   ++    G  AD++
Sbjct: 198 MCAKAAGAAQVIALEMSSARKAKAK-EAGANVVL---DPSQCDALAEIRALTAGLGADVS 253

Query: 263 LDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTC 322
            +C G + T +LA+  +R  G+  LVG+          +  S E  + G   Y+  +   
Sbjct: 254 FECIGNKHTAKLAIDTIRKAGKCVLVGIFEEPSEFNFFELVSTEKQVLGALAYNGEFADV 313

Query: 323 IALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLT 369
           IA +A GR++++PL+T R +GLE+  +E  FE         VK++++
Sbjct: 314 IAFIADGRLDIRPLVTGR-IGLEQ-IVELGFEELVNNKEENVKIIVS 358

ref|XP_614110.1| PREDICTED: similar to Sorbitol dehydrogenase (L-iditol 2-dehydrogenase), partial [Bos taurus]
(154 aa)

Score: 178 bits (451), Expect: 2.48311e-43
Length: 148, Idn/Pos/Gap = 85/107/0 (57%/72%/0%)

Query:  48 VRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGDRVAL 107
           V L+M  VGICGSDVHYW HG  G F +  PM++GHE++G V  +G+ V  LQ GDRVA+
Sbjct:   1 VLLKMHSVGICGSDVHYWQHGRIGDFVVKKPMVLGHEASGTVVKVGSLVRHLQPGDRVAI  60

Query: 108 EPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPESVSLEEGAM 167
           EPG P    + C+ GRYNL P I F ATPP DG+L R+  H A +CY+LP++V+ EEGA+
Sbjct:  61 EPGAPRETDEFCKIGRYNLSPTIFFCATPPDDGNLCRFYKHNANFCYKLPDNVTFEEGAL 120

Query: 168 CEPLSVAVHANRRAGTTIGSLVLVLGAG 195
            EPLSV +HA RRAG T+G+ VLV GAG
Sbjct: 121 IEPLSVGIHACRRAGVTLGNKVLVCGAG 148

gb|AAU22906.1| Zinc-containing alcohol dehydrogenase [Bacillus subtilis phage PBSX]
ref|YP_090952.1| YjmD [Bacillus licheniformis ATCC 14580]
ref|YP_078544.1| Zinc-containing alcohol dehydrogenase [Bacillus licheniformis ATCC 14580]
gb|AAU40259.1| YjmD [Bacillus licheniformis DSM 13]
(338 aa)

Score: 177 bits (450), Expect: 2.98343e-43
Length: 348, Idn/Pos/Gap = 115/177/17 (33%/50%/4%)

Query:  25 GVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHE  84
            V+ +P  +       P PA GEV ++++  GICGSDVH++  GS  P+  + P I GHE
Sbjct:   4 AVMTKPYSIEFHDIPRPEPASGEVLVKIKAAGICGSDVHFY-DGS-NPYAQY-PQIFGHE  60

Query:  85 SAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLAR 144
            AG++E  GAGV     G+RV +EP +PC  C  CR+GR N C NI    +    G  A 
Sbjct:  61 LAGIIEKTGAGVRGRSAGERVVIEPAIPCGGCYPCRKGRTNACMNIDMIGSVR-RGGFAD 119

Query: 145 YVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGL-LNCM 203
           ++  P    + +PE +     A+CEP S+   A RRA    G  +++LG GPIGL +   
Sbjct: 120 FIIVPETHVHPIPEQMDFATAALCEPFSIGAQAVRRADIQTGETIVILGMGPIGLTILAQ 179

Query: 204 VAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIAL 263
           V K F   +I V  + + RL  AE   GADAVI      E DA  ++ +   G  A I  
Sbjct: 180 VKKRFDVRVIAVDPVRE-RLELAEAF-GADAVIQP---GEEDAEQMILKLTGGEGAGIVF 234

Query: 264 DCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCI 323
           + AG+ +T+  ++ +    GRI +VG+    + +P +  + ++I+I+G     N +P  I
Sbjct: 235 EAAGIPATIEQSVRLAAAAGRIVIVGLTGRNVTIPGLLLTKKDIEIYGTKHSVNQFPGVI 294

Query: 324 ALLASGRVNVKPLITH--RFMGLEESSLEAAFETARTAANGAVKVMLT 369
             L       +  +T    FM +EE     A + A+   +   K++L+
Sbjct: 295 QFLNENPEIARAFVTEIMPFMEIEE-----ALKKAKNCPHQVTKIILS 337

ref|ZP_00311521.1| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Clostridium thermocellum ATCC 27405]
(339 aa)

Score: 177 bits (449), Expect: 4.13084e-43
Length: 316, Idn/Pos/Gap = 112/166/9 (35%/52%/2%)

Query:  27 LVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESA  86
           +V P ++       P   PG+V +++  +GICGSD+H   HG   PF  + P+  GHE +
Sbjct:   1 MVSPGKIEFHEVEKPELKPGQVLIKIMRIGICGSDIHVN-HGK-HPFTKY-PVTQGHEVS  57

Query:  87 GVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYV 146
           G +  +   V  L+VG +V +EP V C +C  CR G+YNLC  +K      V G+ + Y 
Sbjct:  58 GKIVEVAEDVEHLKVGQKVTIEPQVVCGKCHPCRTGKYNLCEELKVMGFQTV-GAGSEYF 116

Query: 147 CHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAK 206
              A     +P+ +S +E AM EPL+V VHA  R G      ++V+GAGPIG+L     K
Sbjct: 117 AVDAKNVTTVPDHLSYDEAAMIEPLAVTVHAANRVGDVKDKDIVVIGAGPIGILLVQTLK 176

Query: 207 AFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCA 266
           A GA  ++VTD+ D RL  A    GAD  +NT+  D  +A L   +     +AD+  DCA
Sbjct: 177 AKGARKVMVTDVSDYRLELA-LKCGADFAVNTKKEDFGEAML---RCFGPDKADVIYDCA 232

Query: 267 GLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNT-YPTCIAL 325
           G  +TM  A+   R G  I LV +      V L   + +E+D+     Y +  Y   I L
Sbjct: 233 GNNTTMEQAIKHSRKGSIIVLVAVFEGMATVDLATLNDKELDLNTTMMYRHEDYVEAIEL 292

Query: 326 LASGRVNVKPLITHRF 341
           + +G+V + PL++  F
Sbjct: 293 VEAGKVKLTPLMSKHF 308

ref|ZP_00215235.1| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Burkholderia cepacia R18194]
(354 aa)

Score: 177 bits (449), Expect: 4.52792e-43
Length: 318, Idn/Pos/Gap = 114/166/14 (35%/52%/4%)

Query:  32 ELRVMLRSVPA-PAPGEVRLQMRCVGICGSDVHYWWHGSCG-PFRLHDPM-------IIG  82
           ++RV    VP  P  G V +++   GICGSD+H +  G    P     P+       I+G
Sbjct:  11 DIRVEQVPVPERPPAGWVTIRVHWCGICGSDLHEYVAGPVFIPVDAPHPLTGLKGQCILG  70

Query:  83 HESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSL 142
           HE +G +  LGAGVT   VGDRV  +    C  C  C+ G YN+C N+ F      +G+ 
Sbjct:  71 HEFSGEIAELGAGVTGFAVGDRVTADACQHCGTCWYCKHGLYNICENLAFTGLMN-NGAF 129

Query: 143 ARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNC 202
           A YV  PA   Y+LP+    E GA+ EPL+V +HA ++AG  +G  V+V+GAG IGL   
Sbjct: 130 AEYVNVPAELLYKLPDDFPTEAGALIEPLAVGLHAVKKAGNIVGQTVVVVGAGTIGLCTI 189

Query: 203 MVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIA 262
           M AKA GA  ++  ++   R   A    GA  VI+ +     DA   V+    G  AD++
Sbjct: 190 MCAKAAGAGRVIALEMSAARKQKA-LEVGASVVIDPK---TSDAIAEVKALTGGYGADVS 245

Query: 263 LDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTC 322
            +C G  +T +LA+ V+R  G+  +VG+          D  S E ++ G   Y+  +   
Sbjct: 246 FECIGHTTTAKLAIDVIRKAGKSVMVGIFEEPAPFNFFDIVSTEKEVIGSLAYNGEFADV 305

Query: 323 IALLASGRVNVKPLITHR 340
           I  +A GR++V+PLIT R
Sbjct: 306 IRFIADGRIDVQPLITGR 323

ref|ZP_00221639.1| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Burkholderia cepacia R1808]
(354 aa)

Score: 177 bits (448), Expect: 5.30576e-43
Length: 318, Idn/Pos/Gap = 113/169/14 (35%/53%/4%)

Query:  32 ELRVMLRSVPA-PAPGEVRLQMRCVGICGSDVHYWWHGSCG-PFRLHDPM-------IIG  82
           ++RV    VP  P  G V++++   GICGSD+H +  G    P     P+       I+G
Sbjct:  11 DIRVEEVPVPGHPPAGWVQIRVHWCGICGSDLHEYVAGPVFIPVDAPHPLTGLKGQCILG  70

Query:  83 HESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSL 142
           HE +G + ALGAGVT   +G+RV  +    C  C  CR G YN+C N+ F      +G+ 
Sbjct:  71 HEFSGEIAALGAGVTGFALGERVTADACQHCGTCWYCRHGMYNICENLAFTGLMN-NGAF 129

Query: 143 ARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNC 202
           A YV  PA   Y+LP++   E GA+ EPL+V ++A ++AG  +G  V+V+GAG IGL   
Sbjct: 130 AEYVNVPAELLYKLPDNFPTEAGALIEPLAVGMYAVKKAGNIVGQTVVVVGAGTIGLCTI 189

Query: 203 MVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIA 262
           M AKA GA  ++  ++   R   A    GA  VI+ +     DA   V+    G  AD++
Sbjct: 190 MCAKAAGAGRVIALEMSAARKQKA-LEVGATVVIDPK---ASDAIAEVKALTGGYGADVS 245

Query: 263 LDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTC 322
            +C G  +T +LA+ V+R  G+  +VG+          D  S E ++ G   Y+  +   
Sbjct: 246 FECIGHTATAKLAIDVIRKAGKSVMVGIFEEPTSFNFFDIVSTEKEVIGSLAYNGEFADV 305

Query: 323 IALLASGRVNVKPLITHR 340
           I  +A GR++V+PLIT R
Sbjct: 306 IRFIADGRIDVQPLITGR 323

ref|ZP_00088750.2| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Azotobacter vinelandii]
(352 aa)

Score: 176 bits (446), Expect: 8.7532e-43
Length: 324, Idn/Pos/Gap = 116/175/15 (35%/54%/4%)

Query:  32 ELRVMLRSVPA-PAPGEVRLQMRCVGICGSDVHYWWHGSCG-PFRLHDPM-------IIG  82
           ++RV    +PA P PG V++++   GICGSD+H +  G    P     P+       I+G
Sbjct:  11 DIRVENVPLPANPPPGWVQIRVDWCGICGSDLHEYVAGPVFIPVEKPHPLTGIQGQCILG  70

Query:  83 HESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSL 142
           HE +G +  LG GV+    G+R+A +    C  C  CR G YNLC  + F      +G+ 
Sbjct:  71 HEFSGEIVKLGTGVSGFAPGERIAADACQHCGTCYYCRSGLYNLCEKLAFTGLMN-NGAF 129

Query: 143 ARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNC 202
           A  V  PA   Y+LP    +E GA+ EPL+V +HA ++AG  +G  V+V+GAG IGL   
Sbjct: 130 AELVNVPAELLYKLPADFPVEAGALIEPLAVGMHAVKKAGNLLGRNVVVVGAGTIGLCTI 189

Query: 203 MVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIA 262
           M AKA GA+ ++  ++   R A A    GA  V++ +   E DA   ++   +G  AD++
Sbjct: 190 MCAKAAGAAQVIALEMSSARKAKA-LEVGASLVLDPK---ECDALAEIRARTNGLGADVS 245

Query: 263 LDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTC 322
            +C G + T +LA+ V+R  G+  LVG+          +  S E  + G   Y+  +   
Sbjct: 246 FECIGNKHTAKLAIDVIRNAGKSVLVGIFEEPSSFNFFELVSTEKQVIGALAYNGEFADV 305

Query: 323 IALLASGRVNVKPLITHRFMGLEE 346
           IA +A GR++V+PLIT R +GLEE
Sbjct: 306 IAFIADGRLDVEPLITGR-IGLEE 328

gb|AAB58982.1| 2,3-butanediol dehydrogenase [Pseudomonas putida]
prf||2104227E 2,3-butanediol dehydrogenase
(362 aa)

Score: 176 bits (446), Expect: 9.20256e-43
Length: 347, Idn/Pos/Gap = 119/182/16 (34%/52%/4%)

Query:  32 ELRVMLRSVPA-PAPGEVRLQMRCVGICGSDVHYWWHGSCG-PFRLHDPM-------IIG  82
           ++RV    +PA PAPG V++++   GICGSD+H +  G    P     P+       I+G
Sbjct:  19 DIRVEQVPLPADPAPGWVQIKVDWCGICGSDLHEYVAGPVFIPVEAPHPLTGIQGQCILG  78

Query:  83 HESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSL 142
           HE  G +  LG GV    VGD VA +    C  C  C  G YN+C  + F      +G+ 
Sbjct:  79 HEFCGQIAKLGEGVEGFAVGDPVAADACQHCGTCYYCTHGLYNICERLAFTGLMN-NGAF 137

Query: 143 ARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNC 202
           A  V  PA   YRLP+    E GA+ EPL+V +HA ++AG+ +G  V+V+GAG IGL   
Sbjct: 138 AELVNVPANLLYRLPQGFPPEAGALIEPLAVGMHAVKKAGSLLGQTVVVVGAGTIGLCTI 197

Query: 203 MVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIA 262
           M AKA GA+ ++  ++   R A A+   GA  V+   D  + DA   ++    G  AD++
Sbjct: 198 MCAKAAGAAQVIALEMSSARKAKAK-EVGATVVL---DPSQCDALAQIRALTFGLGADVS 253

Query: 263 LDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTC 322
            +C G + T +LA+  +R  G+  LVG+          +  S E  + G   Y+  +   
Sbjct: 254 FECIGNKHTAKLAIDTIRKAGKCVLVGIFEEPSEFNFFELVSTEKQVLGALAYNGEFADV 313

Query: 323 IALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLT 369
           IA +A GR++++PL+T R +GLE+  +E  FE         VK++++
Sbjct: 314 IAFIADGRLDIRPLVTGR-IGLEQ-IVELGFEELVNNKEENVKIIVS 358

ref|YP_088148.1| Tdh protein [Mannheimia succiniciproducens MBEL55E]
gb|AAU37563.1| Tdh protein [Mannheimia succiniciproducens MBEL55E]
(347 aa)

Score: 175 bits (443), Expect: 2.26601e-42
Length: 319, Idn/Pos/Gap = 107/164/18 (33%/51%/5%)

Query:  30 PRELRVMLRSVPAPAPGEVRLQMRCV--GICGSDVHYWWHGSCGPFRLHDPMIIGHESAG  87
           P+++ VM +S+      + +  ++    GICGSD+HY+ +G  G + +  PMI+GHE  G
Sbjct:  14 PKDVGVMEQSINYDESSKEQTLVKITRGGICGSDLHYYQYGKVGNYEIKHPMILGHEVIG  73

Query:  88 VVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFAT----PPVDGSLA 143
            V    A    L VG +VA+ P  PCL C+ C  G  N C  ++FF +    P VDG   
Sbjct:  74 TVVKTNA--PDLYVGQKVAINPSKPCLTCKYCLSGDTNQCETMRFFGSAMYNPHVDGGFT 131

Query: 144 RYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCM 203
           +Y     + C   P+ VS +  A  EPL+V +HA ++AG   G  V V G GPIG L   
Sbjct: 132 QYKVVDNSQCIDYPQDVSDDIMAFAEPLAVTIHAAKQAGDLAGKRVFVSGVGPIGCLAVA 191

Query: 204 VAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTR-DLDEHDAALVVQQALDGAQADIA 262
             KA GA  IVV+D+  R L  A    GA   +N + D  E+ A           + D++
Sbjct: 192 AIKASGAKEIVVSDLSRRCLDLA-LEMGATKALNAKDDFSEYMA--------HKGEFDVS 242

Query: 263 LDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTC 322
            + +G  S++   + V +  G I  +GMG +    P++   ++EI + G FR+   + T 
Sbjct: 243 FEASGHPSSIERCLAVTKARGTIIQIGMGGAIPEFPIMTLIAKEICLKGSFRFIEEFNTS 302

Query: 323 IALLASGRVNVKPLITHRF 341
           +  L+SG+VN  PL++  F
Sbjct: 303 VEWLSSGKVNPLPLLSATF 321

ref|NP_252842.1| 2,3-butanediol dehydrogenase [Pseudomonas aeruginosa PAO1]
gb|AAG07540.1| 2,3-butanediol dehydrogenase [Pseudomonas aeruginosa PAO1]
pir||C83128 2,3-butanediol dehydrogenase PA4153 [imported] - Pseudomonas aeruginosa (strain PAO1)
(363 aa)

Score: 174 bits (441), Expect: 3.86523e-42
Length: 347, Idn/Pos/Gap = 121/180/16 (34%/51%/4%)

Query:  32 ELRVMLRSVPA-PAPGEVRLQMRCVGICGSDVHYWWHGSC-------GPFR-LHDPMIIG  82
           ++RV    +PA P PG V++++   GICGSD+H +  G          P   L D  I+G
Sbjct:  21 DIRVEDVPLPAEPPPGWVQIRVHWCGICGSDLHEYLAGPVFIPVEAPHPLTGLKDQCILG  80

Query:  83 HESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSL 142
           HE +G +  LG GVT   VG  VA +    C  C  CR G YN+C N+ F      +G+ 
Sbjct:  81 HEFSGEIVRLGNGVTGFAVGQAVAADACQHCGTCYYCRHGLYNICENLAFTGLMN-NGAF 139

Query: 143 ARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNC 202
           A YV  PA   Y LP     E GA+ EPL+V +HA ++AG+ +G  V+V+GAG IGL   
Sbjct: 140 AEYVNVPANLLYALPAGFPSEAGALIEPLAVGMHAVKKAGSLLGQNVVVVGAGTIGLSTI 199

Query: 203 MVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIA 262
           M A+A GA+ ++  ++   R A A    GA  V+   D    DA   ++    G  AD++
Sbjct: 200 MCARAAGAAQVIALEMSSARKAKA-LEVGASQVL---DPSRCDALGEIRALTGGLGADVS 255

Query: 263 LDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTC 322
            +C G + T +LA+  +R  G+  LVG+          +  S E  + G   Y+  +   
Sbjct: 256 FECIGNKHTAKLAIDAIRKAGKCVLVGIFEEPSEFNFFELVSTEKQLLGALAYNGEFADV 315

Query: 323 IALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLT 369
           IA +A GR+++ PL+T R +GLEE  +E  FE         VK++++
Sbjct: 316 IAFIADGRLDIAPLVTGR-IGLEE-IVERGFEELVNNKEHNVKIIVS 360

gb|AAT51354.1| PA4153 [synthetic construct]
(364 aa)

Score: 174 bits (441), Expect: 3.99641e-42
Length: 347, Idn/Pos/Gap = 121/180/16 (34%/51%/4%)

Query:  32 ELRVMLRSVPA-PAPGEVRLQMRCVGICGSDVHYWWHGSC-------GPFR-LHDPMIIG  82
           ++RV    +PA P PG V++++   GICGSD+H +  G          P   L D  I+G
Sbjct:  21 DIRVEDVPLPAEPPPGWVQIRVHWCGICGSDLHEYLAGPVFIPVEAPHPLTGLKDQCILG  80

Query:  83 HESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSL 142
           HE +G +  LG GVT   VG  VA +    C  C  CR G YN+C N+ F      +G+ 
Sbjct:  81 HEFSGEIVRLGNGVTGFAVGQAVAADACQHCGTCYYCRHGLYNICENLAFTGLMN-NGAF 139

Query: 143 ARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNC 202
           A YV  PA   Y LP     E GA+ EPL+V +HA ++AG+ +G  V+V+GAG IGL   
Sbjct: 140 AEYVNVPANLLYALPAGFPSEAGALIEPLAVGMHAVKKAGSLLGQNVVVVGAGTIGLSTI 199

Query: 203 MVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIA 262
           M A+A GA+ ++  ++   R A A    GA  V+   D    DA   ++    G  AD++
Sbjct: 200 MCARAAGAAQVIALEMSSARKAKA-LEVGASQVL---DPSRCDALGEIRALTGGLGADVS 255

Query: 263 LDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTC 322
            +C G + T +LA+  +R  G+  LVG+          +  S E  + G   Y+  +   
Sbjct: 256 FECIGNKHTAKLAIDAIRKAGKCVLVGIFEEPSEFNFFELVSTEKQLLGALAYNGEFADV 315

Query: 323 IALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLT 369
           IA +A GR+++ PL+T R +GLEE  +E  FE         VK++++
Sbjct: 316 IAFIADGRLDIAPLVTGR-IGLEE-IVERGFEELVNNKEHNVKIIVS 360

ref|ZP_00137632.1| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Pseudomonas aeruginosa UCBPP-PA14]
(363 aa)

Score: 173 bits (438), Expect: 7.8557e-42
Length: 347, Idn/Pos/Gap = 120/180/16 (34%/51%/4%)

Query:  32 ELRVMLRSVPA-PAPGEVRLQMRCVGICGSDVHYWWHGSC-------GPFR-LHDPMIIG  82
           ++RV    +PA P PG V++++   GICGSD+H +  G          P   L D  I+G
Sbjct:  21 DIRVEDVPLPAEPPPGWVQIRVHWCGICGSDLHEYLAGPVFIPVEAPHPLTGLKDQCILG  80

Query:  83 HESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSL 142
           HE +G +  LG GVT   +G  VA +    C  C  CR G YN+C N+ F      +G+ 
Sbjct:  81 HEFSGEIVRLGNGVTGFALGQAVAADACQHCGTCYYCRHGLYNICENLAFTGLMN-NGAF 139

Query: 143 ARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNC 202
           A YV  PA   Y LP     E GA+ EPL+V +HA ++AG+ +G  V+V+GAG IGL   
Sbjct: 140 AEYVNVPANLLYALPAGFPSEAGALIEPLAVGMHAVKKAGSLLGQNVVVVGAGTIGLCTI 199

Query: 203 MVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIA 262
           M A+A GA+ ++  ++   R A A    GA  V+   D    DA   ++    G  AD++
Sbjct: 200 MCARAAGAAQVIALEMSSARKAKA-LEVGASQVL---DPSRCDALGEIRALTGGLGADVS 255

Query: 263 LDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTC 322
            +C G + T +LA+  +R  G+  LVG+          +  S E  + G   Y+  +   
Sbjct: 256 FECIGNKHTAKLAIDAIRKAGKCVLVGIFEEPSEFNFFELVSTEKQLLGALAYNGEFADV 315

Query: 323 IALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLT 369
           IA +A GR+++ PL+T R +GLEE  +E  FE         VK++++
Sbjct: 316 IAFIADGRLDIAPLVTGR-IGLEE-IVERGFEELVNNKEHNVKIIVS 360

gb|EAK80794.1| hypothetical protein UM00412.1 [Ustilago maydis 521]
ref|XP_398027.1| hypothetical protein UM00412.1 [Ustilago maydis 521]
(483 aa)

Score: 173 bits (438), Expect: 8.39797e-42
Length: 221, Idn/Pos/Gap = 101/137/7 (45%/61%/3%)

Query:  21 ANPCGVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMI  80
           +N   VL   ++LR+  R   AP   EV++++R  G+CGSD+HY+ HG  G F L   M 
Sbjct:  44 SNTSAVLHGAKDLRIEERPYAAPIGDEVQIRVRATGLCGSDLHYYLHGRNGDFALQHSMC 103

Query:  81 IGHESAGVVEALGAGVTS---LQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFAT-- 135
           +GHESAG + A+G  V +   L VGDRVA+E G  C  C +CR+GRYNLC  ++F ++  
Sbjct: 104 LGHESAGEIVAVGPNVPASLGLAVGDRVAIEAGRFCGSCLKCRDGRYNLCKQMRFASSAK 163

Query: 136 --PPVDGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLG 193
             P +DG+L +Y+  P+   ++LP +VSL   A+CEPLSV +   RR+    G  VLV G
Sbjct: 164 THPHLDGTLQKYMNWPSWLVHKLPANVSLTSAALCEPLSVVLQGIRRSQLQPGQSVLVYG 223

Query: 194 AGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADA 234
           AG +GLL C  AKA GAS +   DID  RLAFA  +  ADA
Sbjct: 224 AGAVGLLACAAAKASGASFVAAVDIDQGRLAFAAANGWADA 264

ref|NP_830481.1| (R,R)-butanediol dehydrogenase [Bacillus cereus ATCC 14579]
gb|AAP07682.1| (R,R)-butanediol dehydrogenase [Bacillus cereus ATCC 14579]
(350 aa)

Score: 172 bits (435), Expect: 1.91829e-41
Length: 346, Idn/Pos/Gap = 106/178/14 (30%/51%/4%)

Query:  31 RELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCG-PFRLHD------PMIIGH  83
           R++RV     P   PG V+++++  GICG+D+H +  G    P   H       P+I+GH
Sbjct:  10 RDVRVEEVPEPTVKPGTVKIKVKWCGICGTDLHEYLAGPIFIPTEEHPLTHVKAPVILGH  69

Query:  84 ESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLA 143
           E +G V  +G GVTS +VGDRV +EP   C +C+ C+ G YN+C  + F       G  +
Sbjct:  70 EFSGEVIEIGEGVTSHKVGDRVVVEPIYSCGKCEACKHGHYNVCEQLVFHGLGGEGGGFS 129

Query: 144 RYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCM 203
            Y   P    + +P+ ++ E+GA+ EP +VAVHA R++    G  V V G GPIGLL   
Sbjct: 130 EYTVVPEDMVHHIPDEMTYEQGALVEPAAVAVHAVRQSKLKEGEAVAVFGCGPIGLLVIQ 189

Query: 204 VAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIAL 263
            AKA GA+ ++  ++   R   A+  AGAD V+N       D    ++   +G   +++ 
Sbjct: 190 AAKAAGATPVIAVELSKERQELAKL-AGADYVLNPA---TQDVLAEIRNLTNGLGVNVSF 245

Query: 264 DCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCI 323
           +  G+E  +R A+      G+  +V +      +   +   +E ++ G+  Y + +P  I
Sbjct: 246 EVTGVEVVLRQAIESTSFEGQTVIVSVWEKDATITPNNLVLKEKEVIGILGYRHIFPAVI 305

Query: 324 ALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLT 369
            L++SG++  + LIT +     +  +E  FE A       VK++++
Sbjct: 306 KLISSGQIQAEKLITKKIT--VDQVVEEGFE-ALVKDKTQVKILVS 348

ref|YP_082190.1| zinc-containing alcohol dehydrogenase, long-chain [Bacillus cereus ZK]
gb|AAU19657.1| zinc-containing alcohol dehydrogenase, long-chain [Bacillus cereus ZK]
ref|YP_034931.1| zinc-containing alcohol dehydrogenase, long-chain [Bacillus thuringiensis serovar konkukian str. 97-27]
gb|AAT63972.1| zinc-containing alcohol dehydrogenase, long-chain [Bacillus thuringiensis serovar konkukian str. 97-27]
(350 aa)

Score: 171 bits (434), Expect: 2.56887e-41
Length: 346, Idn/Pos/Gap = 106/178/14 (30%/51%/4%)

Query:  31 RELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCG-PFRLHD------PMIIGH  83
           R++RV     P   PG V+++++  GICG+D+H +  G    P   H       P+I+GH
Sbjct:  10 RDVRVEEVPEPTVKPGAVKIKVKWCGICGTDLHEYLAGPIFIPTEEHPLTHVKAPVILGH  69

Query:  84 ESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLA 143
           E +G V  +G GVTS +VGDRV +EP   C +C+ C+ G YN+C  + F       G  +
Sbjct:  70 EFSGEVVEIGEGVTSHKVGDRVVVEPIYSCGKCEACKHGHYNVCEQLVFHGLGGEGGGFS 129

Query: 144 RYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCM 203
            Y   P    + +P+ ++ E+GA+ EP +VAVHA R++    G  V V G GPIGLL   
Sbjct: 130 EYTVVPEDMVHHIPDEMTYEQGALVEPAAVAVHAVRQSKLKEGEAVAVFGCGPIGLLVIQ 189

Query: 204 VAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIAL 263
            AKA GA+ ++  ++   R   A+  AGAD V+N       D    ++   +G   +++ 
Sbjct: 190 AAKAAGATPVIAVELSKERQELAKL-AGADYVLNPA---TQDVLAEIRNLTNGLGVNVSF 245

Query: 264 DCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCI 323
           +  G+E  +R A+      G+  +V +      +   +   +E ++ G+  Y + +P  I
Sbjct: 246 EVTGVEVVLRQAIESTSFEGQTVIVSVWEKDATITPNNLVLKEKEVVGILGYRHIFPAVI 305

Query: 324 ALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLT 369
            L++SG++  + LIT +     +  +E  FE A       VK++++
Sbjct: 306 KLISSGQIQAEKLITKKIT--VDQVVEEGFE-ALVKDKTQVKILVS 348

dbj|BAB60856.1| acetylacetoin reductase [Bacillus cereus]
(349 aa)

Score: 171 bits (433), Expect: 3.01018e-41
Length: 331, Idn/Pos/Gap = 103/171/13 (31%/51%/3%)

Query:  31 RELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCG-PFRLHD------PMIIGH  83
           R++RV     P   PG V+++++  GICG+D+H +  G    P   H       P+I+GH
Sbjct:  10 RDVRVEEVPEPTVKPGAVKIKVKWCGICGTDLHEYLAGPIFIPTEEHPLTHVKAPVILGH  69

Query:  84 ESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLA 143
           E +G V  +G GVTS +VGDRV +EP   C +C+ C+ G YN+C  + F       G  +
Sbjct:  70 EFSGEVVEIGEGVTSHKVGDRVVVEPIYSCGKCEACKHGHYNVCEQLVFHGLGGEGGGFS 129

Query: 144 RYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCM 203
            Y   P    + +P+ ++ E+GA+ EP +VAVHA R++    G  V V G GPIGLL   
Sbjct: 130 EYTVVPEDMVHHIPDEMTYEQGALVEPAAVAVHAVRQSKLKEGEAVAVFGCGPIGLLVIQ 189

Query: 204 VAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIAL 263
            AKA GA+ ++  ++   R   A+  AGAD V+N       D    ++   +G   +++ 
Sbjct: 190 AAKAAGATPVIAVELSKERQELAKL-AGADYVLNPA---TQDVLAEIRNLTNGLGVNVSF 245

Query: 264 DCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCI 323
           +  G+E  +R A+      G+  +V +      +   +   +E ++ G+  Y + +P  I
Sbjct: 246 EVTGVEVVLRQAIESTSFEGQTVIVSVWEKDATITPNNLVLKEKEVVGILGYRHIFPAVI 305

Query: 324 ALLASGRVNVKPLITHRFMGLEESSLEAAFE 354
            L++SG++  + LIT +     +  +E  FE
Sbjct: 306 KLISSGQIQAEKLITKKIT--VDQVVEEGFE 334

ref|NP_977067.1| alcohol dehydrogenase, zinc-containing [Bacillus cereus ATCC 10987]
gb|AAS39675.1| alcohol dehydrogenase, zinc-containing [Bacillus cereus ATCC 10987]
(350 aa)

Score: 171 bits (433), Expect: 3.21796e-41
Length: 346, Idn/Pos/Gap = 106/178/14 (30%/51%/4%)

Query:  31 RELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCG-PFRLHD------PMIIGH  83
           R++RV     P   PG V+++++  GICG+D+H +  G    P   H       P+I+GH
Sbjct:  10 RDVRVEEVPEPTVKPGAVKIKVKWCGICGTDLHEYLAGPIFIPKEEHPLTHVKAPVILGH  69

Query:  84 ESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLA 143
           E +G V  +G GVTS +VGDRV +EP   C +C+ C+ G YN+C  + F       G  +
Sbjct:  70 EFSGEVVEIGEGVTSHKVGDRVVVEPIYSCGKCEACKHGHYNVCEQLVFHGLGGEGGGFS 129

Query: 144 RYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCM 203
            Y   P    + +P+ ++ E+GA+ EP +VAVHA R++    G  V V G GPIGLL   
Sbjct: 130 EYTVVPEDMVHHIPDEMTYEQGALVEPAAVAVHAVRQSKLKEGEAVAVFGCGPIGLLVIQ 189

Query: 204 VAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIAL 263
            AKA GA+ ++  ++   R   A+  AGAD V+N       D    ++   +G   +++ 
Sbjct: 190 AAKAAGATPVIAVELSKERQELAKL-AGADYVLNPA---TQDVLAEIRNLTNGLGVNVSF 245

Query: 264 DCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCI 323
           +  G+E  +R A+      G+  +V +      +   +   +E ++ G+  Y + +P  I
Sbjct: 246 EVTGVEVVLRQAIESTSFEGQTVIVSVWEKDATITPNNLVLKEKEVVGILGYRHIFPAVI 305

Query: 324 ALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLT 369
            L++SG++  + LIT +     +  +E  FE A       VK++++
Sbjct: 306 KLISSGQIQAEKLITKKIT--VDQVVEEGFE-ALVKDKTQVKILVS 348

emb|CAB13090.1| yjmD [Bacillus subtilis subsp. subtilis str. 168]
ref|NP_389115.1| hypothetical protein BSU12330 [Bacillus subtilis subsp. subtilis str. 168]
gb|AAC46329.1| zinc-containing alcohol dehydrogenase [Bacillus subtilis]
pir||F69852 L-iditol 2-dehydrogenase (EC 1.1.1.14) homolog yjmD - Bacillus subtilis
(339 aa)

Score: 169 bits (427), Expect: 1.43289e-40
Length: 295, Idn/Pos/Gap = 105/162/9 (35%/54%/3%)

Query:  47 EVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGDRVA 106
           EV ++++ VGICGSD+H + HG+     L  P +IGHE  G VEA+GA V SL+ GD V 
Sbjct:  27 EVLVKVKRVGICGSDMHIY-HGTNPLATL--PRVIGHEVTGQVEAVGANVQSLKPGDHVV  83

Query: 107 LEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPESVSLEEGA 166
           +EP   C  C  CR+GR N+C  +  F     DG +  Y+  P    + + + +  EE  
Sbjct:  84 IEPISYCGSCYACRKGRPNVCAKLSVFGVHE-DGGMREYIVLPERQLHAVSKDLPWEEAV 142

Query: 167 MCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFA 226
           M EP ++   A  R     G  VL+ GAGPIG+    +AK  GA+++ +TD+++ RLAFA
Sbjct: 143 MAEPYTIGAQAVWRGQVEKGDTVLIQGAGPIGICVLKMAKLAGAAVM-MTDLNNERLAFA 201

Query: 227 ETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVVRPGGRIC 286
           + + GADAV+N +   EH A  V++   +   A++ +D   L  T  L++  V P G + 
Sbjct: 202 KEN-GADAVVNVQ--AEHVAERVLEWTGNEG-ANVVIDAVCLPETFALSIEAVSPAGHVV 257

Query: 287 LVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASGRVNVKPLITHRF 341
           ++G    A  +  +  + +E+ I G    +N +P  + LL  GR+    L+TH F
Sbjct: 258 VLGFDERAAQISQLPITKKEVTITGSRLQTNQFPKVVELLNGGRLMHNGLVTHTF 312

ref|YP_017304.1| alcohol dehydrogenase, zinc-containing [Bacillus anthracis str. 'Ames Ancestor']
ref|NP_843202.1| alcohol dehydrogenase, zinc-containing [Bacillus anthracis str. Ames]
ref|YP_026918.1| alcohol dehydrogenase, zinc-containing [Bacillus anthracis str. Sterne]
ref|NP_654622.1| adh_zinc, Zinc-binding dehydrogenases [Bacillus anthracis str. A2012]
gb|AAP24688.1| alcohol dehydrogenase, zinc-containing [Bacillus anthracis str. Ames]
gb|AAT29779.1| alcohol dehydrogenase, zinc-containing [Bacillus anthracis str. 'Ames Ancestor']
gb|AAT52969.1| alcohol dehydrogenase, zinc-containing [Bacillus anthracis str. Sterne]
(350 aa)

Score: 169 bits (427), Expect: 1.4449e-40
Length: 346, Idn/Pos/Gap = 105/177/14 (30%/51%/4%)

Query:  31 RELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCG-PFRLHD------PMIIGH  83
           R++RV     P   PG V+++++  GICG+D+H +  G    P   H       P+I+GH
Sbjct:  10 RDVRVEEVPEPTVKPGAVKIKVKWCGICGTDLHEYLAGPIFIPTEEHPLTHVKAPVILGH  69

Query:  84 ESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLA 143
           E +G V  +G GVTS +VGDRV +EP   C +C+ C+ G YN+C  + F       G  +
Sbjct:  70 EFSGEVVEIGEGVTSHKVGDRVVVEPIYSCGKCEACKHGHYNVCEQLVFHGLGGEGGGFS 129

Query: 144 RYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCM 203
            Y   P    + +P+ ++ E+GA+ EP +VAVHA R++    G  V V G GPIGLL   
Sbjct: 130 EYTVVPEDMVHHIPDEMTYEQGALVEPAAVAVHAVRQSKLKEGEAVAVFGCGPIGLLVIQ 189

Query: 204 VAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIAL 263
            AKA GA+ ++  ++   R   A+  AGAD V+N       D    ++   +    +++ 
Sbjct: 190 AAKAAGATPVIAVELSKERQELAKL-AGADYVLNPA---TQDVLAEIRNLTNSLGVNVSF 245

Query: 264 DCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCI 323
           +  G+E  +R A+      G+  +V +      +   +   +E ++ G+  Y + +P  I
Sbjct: 246 EVTGVEVVLRQAIESTSFEGQTVIVSVWEKDATITPNNLVLKEKEVVGILGYRHIFPAVI 305

Query: 324 ALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLT 369
            L++SG++  + LIT +     +  +E  FE A       VK++++
Sbjct: 306 KLISSGQIQAEKLITKKIT--VDQVVEEGFE-ALVKDKTQVKILVS 348

ref|NP_753865.1| Starvation sensing protein rspB [Escherichia coli CFT073]
gb|AAN80430.1| Starvation sensing protein rspB [Escherichia coli CFT073]
(347 aa)

Score: 169 bits (427), Expect: 1.54464e-40
Length: 315, Idn/Pos/Gap = 108/161/13 (34%/51%/4%)

Query:  29 RPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVH-YWWHGSCGPFRLHDPMIIGHESAG  87
           +P +L ++ R +P P+ GEVR++++  GICGSD H Y  H    PF  + P +IGHE  G
Sbjct:  16 KPNQLSIIEREIPTPSAGEVRVKVKLAGICGSDSHIYRGHN---PFAKY-PRVIGHEFFG  71

Query:  88 VVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVC 147
           V++A+G GV S +VG+RVA++P V C  C  C  G+ N+C  +        DG  + Y  
Sbjct:  72 VIDAVGEGVESARVGERVAVDPVVSCGHCYPCSIGKPNVCTTLAVLGV-HADGGFSEYAV 130

Query: 148 HPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKA 207
            PA   +++PE+V+ +   M EP ++A +       T    VLV GAGPIGL    V K 
Sbjct: 131 VPAKNAWKIPEAVADQYAVMIEPFTIAANVTGHGQPTENDTVLVYGAGPIGLTIVQVLKG 190

Query: 208 -FGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCA 266
            +    ++V D  D RL  A+  +GAD  IN          L    A  G +  + +D A
Sbjct: 191 VYNVKNVIVADRIDERLEKAK-ESGADWAINNS-----QTPLGESFAEKGIKPTLIIDAA 244

Query: 267 GLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALL 326
              S ++ A+ +  P  RI L+G  S    V     + +E+ IF     +N +P  I  L
Sbjct: 245 CHPSILKEAVTLASPAARIVLMGFSSEPSEVIQQGITGKELSIFSSRLNANKFPVVIDWL 304

Query: 327 ASGRVNVKPLITHRF 341
           + G +  + LITH F
Sbjct: 305 SKGLIKPEKLITHTF 319

ref|NP_418688.1| L-idonate 5-dehydrogenase, NAD-binding [Escherichia coli K12]
gb|AAC77224.1| L-idonate dehydrogenase; L-idonate 5-dehydrogenase, NAD-binding [Escherichia coli K12]
gb|AAA97164.1| ORF_f343a [Escherichia coli]
pir||S56493 probable alcohol dehydrogenase (EC 1.1.1.-) yjgV - Escherichia coli (strain K-12)
sp|P39346|IDND_ECOLI L-idonate 5-dehydrogenase
(343 aa)

Score: 169 bits (427), Expect: 1.75058e-40
Length: 300, Idn/Pos/Gap = 100/154/19 (33%/51%/6%)

Query:  56 GICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQ 115
           GICGSD+HY+  G  G F +  PM++GHE  G V  + +  + L  G  VA+ P  PC  
Sbjct:  38 GICGSDLHYYQEGKVGNFMIKAPMVLGHEVIGKV--IHSDSSELHEGQTVAINPSKPCGH  95

Query: 116 CQRCREGRYNLCPNIKFFAT----PPVDGSLARYVCHPAAWCYRLPESVSLEEGAMCEPL 171
           C+ C E   N C +++FF +    P VDG   RY     + C   P     +  A  EPL
Sbjct:  96 CKYCIEHNENQCTDMRFFGSAMYFPHVDGGFTRYKMVETSQCVPYPAKADEKVMAFAEPL 155

Query: 172 SVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAG 231
           +VA+HA  +AG   G  V + G GPIG L     K  GA+ IV  D+  R L+  +   G
Sbjct: 156 AVAIHAAHQAGELQGKRVFISGVGPIGCLIVSAVKTLGAAEIVCADVSPRSLSLGK-EMG 214

Query: 232 ADAVINTR--DLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVVRPGGRICLVG 289
           AD ++N +  D+D   A        +    D++ + +G  S++   + V R  G +  VG
Sbjct: 215 ADVLVNPQNDDMDHWKA--------EKGYFDVSFEVSGHPSSVNTCLEVTRARGVMVQVG 266

Query: 290 MGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASGRVNVKPLIT--HRFMGLEES 347
           MG +    P++    +EI + G FR+++ + T ++ LA+G +N  PL++  + F  LEE+
Sbjct: 267 MGGAMAEFPMMTLIGKEISLRGSFRFTSEFNTAVSWLANGVINPLPLLSAEYPFTDLEEA 326

ref|NP_757216.1| L-idonate 5-dehydrogenase [Escherichia coli CFT073]
gb|AAN83790.1| L-idonate 5-dehydrogenase [Escherichia coli CFT073]
(343 aa)

Score: 168 bits (425), Expect: 3.06172e-40
Length: 300, Idn/Pos/Gap = 100/153/19 (33%/51%/6%)

Query:  56 GICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQ 115
           GICGSD+HY+  G  G F +  PM++GHE  G V  + +  + L  G  VA+ P  PC  
Sbjct:  38 GICGSDLHYYQEGKVGNFMIKAPMVLGHEVIGKV--IHSDSSKLHEGQTVAINPSKPCGH  95

Query: 116 CQRCREGRYNLCPNIKFFAT----PPVDGSLARYVCHPAAWCYRLPESVSLEEGAMCEPL 171
           C+ C E   N C  ++FF +    P VDG   RY     + C   P     +  A  EPL
Sbjct:  96 CKYCIEHNENQCTEMRFFGSAMYFPHVDGGFTRYKMVETSQCVPYPAKADEKVMAFAEPL 155

Query: 172 SVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAG 231
           +VA+HA  +AG   G  V + G GPIG L     K  GA+ IV  D+  R L+  +   G
Sbjct: 156 AVAIHAAHQAGELQGKRVFISGVGPIGCLIVSAVKTLGAAEIVCADVSPRSLSLGK-EMG 214

Query: 232 ADAVINTR--DLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVVRPGGRICLVG 289
           AD ++N +  D+D   A        +    D++ + +G  S++   + V R  G +  VG
Sbjct: 215 ADVLVNPQNDDMDHWKA--------EKGYFDVSFEVSGHPSSVNTCLEVTRARGVMVQVG 266

Query: 290 MGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASGRVNVKPLIT--HRFMGLEES 347
           MG +    P++    +EI + G FR+++ + T ++ LA+G +N  PL++  + F  LEE+
Sbjct: 267 MGGAMAEFPMMTLIGKEISLKGSFRFTSEFNTAVSWLANGVINPLPLLSAEYPFTDLEEA 326

gb|AAU20816.1| NAD-dependent sorbital dehydrogenase 8 [Malus x domestica]
(126 aa)

Score: 166 bits (421), Expect: 6.99368e-40
Length: 125, Idn/Pos/Gap = 79/100/0 (63%/80%/0%)

Query:  77 DPMIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATP 136
           +PM+IGHE AG+V+ +G+ V  L  GDRVA+EPG+ C  CQ+C+ GRYNLCP++KFFATP
Sbjct:   1 EPMVIGHECAGIVDKVGSEVKHLVPGDRVAVEPGISCAHCQQCKGGRYNLCPDMKFFATP  60

Query: 137 PVDGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGP 196
           PV GSLA  + HPA  C++LPE+VSLEEGAMCEPLSV VHA RRA     + VL++GAGP
Sbjct:  61 PVHGSLANQIVHPADLCFKLPENVSLEEGAMCEPLSVGVHACRRANVGPETTVLIVGAGP 120

Query: 197 IGLLN 201
           IGL++
Sbjct: 121 IGLVS 125

ref|NP_378341.1| hypothetical sorbitol dehydrogenase [Sulfolobus tokodaii str. 7]
dbj|BAB67450.1| 339aa long hypothetical sorbitol dehydrogenase [Sulfolobus tokodaii str. 7]
(339 aa)

Score: 166 bits (421), Expect: 7.92612e-40
Length: 347, Idn/Pos/Gap = 119/178/31 (34%/51%/8%)

Query:  34 RVMLRSVPAPA---PGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVE  90
           +V+++ +P P     G+V ++M+  G+CG+DV       CG +    P I+GHE AG+++
Sbjct:  10 KVVIKEIPKPIIKDKGDVIVKMKACGLCGTDVE----KICGQYTASQP-ILGHEPAGIID  64

Query:  91 ALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPA 150
              + V  L+ G RV     VPC +C  C  G   +CP  +     P  G  A Y   PA
Sbjct:  65 E--SSVDFLKSGQRVFAHHHVPCYECYYCTHGSPTMCPYYRKTNLDP--GGFAEYFRVPA 120

Query: 151 AWCYR-----LPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVA 205
               R     LP+SVS +EGA  EPL+  V A RR     G  VLV+GAGP+GLL+ M+A
Sbjct: 121 WNVIRGGILILPDSVSFDEGAFIEPLATVVRAQRRVKINKGDSVLVVGAGPMGLLHVMMA 180

Query: 206 KAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDC 265
           KA GAS ++ +D+ D R+ +A T  GAD  +N R   + D    V++  DG  AD+A+  
Sbjct: 181 KANGASTVITSDVSDFRIEYA-TKVGADYSLNAR---KTDIPSEVKKLTDGRGADVAIIA 236

Query: 266 AGLESTMRLAMHVVRPGGRICLVGM--GSSAMHVPLVDASSREIDIFGV-FRYSNTYPTC 322
           +G  S +   +  VR GG + L G+    + ++  + +  + EI I              
Sbjct: 237 SGSPSAILSGLLSVRKGGYVLLFGVPYKGTVLNYDISELLNNEISIISSNAAVEEDTKEA 296

Query: 323 IALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANG-AVKVML 368
           + L+   +V+VK LITHRF       L+   E  R A  G A+KV++
Sbjct: 297 LKLIYERKVDVKKLITHRF------PLDEFNEAVRVAKQGEAIKVII 337

ref|YP_219327.1| L-idonate 5-dehydrogenase [Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67]
gb|AAX68246.1| L-idonate 5-dehydrogenase [Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67]
(343 aa)

Score: 166 bits (420), Expect: 9.84635e-40
Length: 311, Idn/Pos/Gap = 106/159/25 (34%/51%/8%)

Query:  56 GICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQ 115
           GICGSD+HY+  G  G F +  PMI+GHE  G +  + +    L+ G  VA+ P  PC  
Sbjct:  38 GICGSDLHYYQEGKVGNFTVKAPMILGHEVIGKI--VRSDSDLLREGQPVAINPSKPCGH  95

Query: 116 CQRCREGRYNLCPNIKFFAT----PPVDGSLARYVCHPAAWCYRLPESVSLEEGAMCEPL 171
           C+ C +   N C  ++FF +    P VDG   R+     A C   PE    +  A  EPL
Sbjct:  96 CKYCLQHEENHCIEMRFFGSAMYFPHVDGGFTRFKAVDTAQCIPWPEQADEKAMAFAEPL 155

Query: 172 SVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAG 231
           +VA+HA   AG   G  V + G GPIG L     K  GA+ +V  DI  R L+ A    G
Sbjct: 156 AVAIHAAHEAGDLQGKRVFISGVGPIGCLIVSAVKTLGAAEVVCADISTRSLSLAR-QMG 214

Query: 232 ADAVINTRDLDEHDAALVVQQALDGAQA-----DIALDCAGLESTMRLAMHVVRPGGRIC 286
           AD ++N     +HD       +LDG +A     DI+ + +G  S++   + V R  G + 
Sbjct: 215 ADTLVNP----QHD-------SLDGWKAEKGYFDISFEVSGHPSSISTCLEVTRAKGVMV 263

Query: 287 LVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASGRVNVKPLIT--HRFMGL 344
            VGMG +  + P++   S+EI + G FR++  + T ++ LA+  +N  PL++  + F  L
Sbjct: 264 QVGMGGAVPNFPMMMVISKEISLKGSFRFTTEFNTAVSWLANRVINPLPLLSAEYPFTDL 323

Query: 345 EESSLEAAFET 355
           E + + A  +T
Sbjct: 324 EAALIFAGDKT 334

ref|NP_416097.1| putative dehydrogenase, NAD(P)-binding, starvation-sensing protein [Escherichia coli K12]
gb|AAC74652.1| starvation sensing protein; putative dehydrogenase, NAD(P)-binding, starvation-sensing protein [Escherichia coli K12]
pir||I81185 starvation-sensing protein rspB (EC 1.1.1.-) - Escherichia coli (strain K-12)
sp|P38105|RSPB_ECOLI Starvation sensing protein rspB
dbj|BAA15306.1| Starvation sensing protein RspB (EC 1.1.1.-). [Escherichia coli]
dbj|BAA15284.1| Starvation sensing protein RspB (EC 1.1.1.-). [Escherichia coli]
gb|AAA21686.1| putative
(339 aa)

Score: 166 bits (419), Expect: 1.27529e-39
Length: 346, Idn/Pos/Gap = 114/171/16 (32%/49%/4%)

Query:  29 RPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVH-YWWHGSCGPFRLHDPMIIGHESAG  87
           +P +L ++ R +P P+ GEVR++++  GICGSD H Y  H    PF  + P +IGHE  G
Sbjct:   8 KPNQLAIVEREIPTPSAGEVRVKVKLAGICGSDSHIYRGHN---PFAKY-PRVIGHEFFG  63

Query:  88 VVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVC 147
           V++A+G GV S +VG+RVA++P V C  C  C  G+ N+C  +        DG  + Y  
Sbjct:  64 VIDAVGEGVESARVGERVAVDPVVSCGHCYPCSIGKPNVCTTLAVLGV-HADGGFSEYAV 122

Query: 148 HPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKA 207
            PA   +++PE+V+ +   M EP ++A +       T    VLV GAGPIGL    V K 
Sbjct: 123 VPAKNAWKIPEAVADQYAVMIEPFTIAANVTGHGQPTENDTVLVYGAGPIGLTIVQVLKG 182

Query: 208 -FGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCA 266
            +    ++V D  D RL  A+  +GAD  IN          L       G +  + +D A
Sbjct: 183 VYNVKNVIVADRIDERLEKAK-ESGADWAINNS-----QTPLGEIFTEKGIKPTLIIDAA 236

Query: 267 GLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALL 326
              S ++ A+ +  P  RI L+G  S    V     + +E+ IF     +N +P  I  L
Sbjct: 237 CHPSILKEAVTLASPAARIVLMGFSSEPSEVIQQGITGKELSIFSSRLNANKFPIVIDWL 296

Query: 327 ASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLTIPE 372
           + G +  + LITH F     +   + FE  +       KV+LT  E
Sbjct: 297 SKGLIKPEKLITHTFDFQHVADAISLFEQDQ---KHCCKVLLTFSE 339

dbj|BAC74337.1| putative L-idonate 5-dehydrogenase [Streptomyces avermitilis MA-4680]
ref|NP_827802.1| putative L-idonate 5-dehydrogenase [Streptomyces avermitilis MA-4680]
(341 aa)

Score: 165 bits (418), Expect: 1.55803e-39
Length: 303, Idn/Pos/Gap = 120/164/19 (39%/54%/6%)

Query:  32 ELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEA  91
           +LRV     PA  PG+  + +R  G+CGSD+HYW HG  G FRL +PM++GHE  G V +
Sbjct:  11 DLRVDELPEPAAGPGQALVAVRYGGVCGSDLHYWRHGGVGDFRLREPMVLGHEVVGTVLS  70

Query:  92 LGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFAT----PPVDGSLARYVC 147
            G G      G  VA+ P  PC  C  C +GR N+C + ++  +    P V G  A  V 
Sbjct:  71 YGPGAAGPAPGTAVAVHPATPCGVCPECADGRANVCRDTRYLGSAARMPHVQGGFAARVV 130

Query: 148 HPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKA 207
            PAA    LPE + L   A+ EPLSVA+HA RRAG   G  VLV GAGPIG L    AKA
Sbjct: 131 VPAAQVRALPEGLDLRRAALAEPLSVALHAVRRAGPVAGRPVLVTGAGPIGCLVVAAAKA 190

Query: 208 FGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAG 267
            GA  + VTD+  R L++A    GAD V+  R  D  DA             D+A++ +G
Sbjct: 191 AGAGRVTVTDLLPRALSYA-AGVGADDVV--RADDPADAGW-------PDSVDVAVEASG 240

Query: 268 LESTMRLAMHVVRPGGRICLVGM---GSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIA 324
           + + +   + +VR GG +  +GM   G +     LV   SREI++ G FR+++ +   + 
Sbjct: 241 VAAGLDTCLRLVRRGGVVVQLGMLPPGQTPFAGNLV--VSREIELRGAFRFADEFDEALT 298

Query: 325 LLA 327
           LLA
Sbjct: 299 LLA 301

ref|NP_694180.1| sorbitol dehydrogenase [Oceanobacillus iheyensis HTE831]
dbj|BAC15214.1| sorbitol dehydrogenase (L-iditol 2-dehydrogenase) [Oceanobacillus iheyensis HTE831]
(342 aa)

Score: 165 bits (418), Expect: 1.6244e-39
Length: 310, Idn/Pos/Gap = 107/161/21 (34%/51%/6%)

Query:  40 VPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSL  99
           VP   P EV++++   GICGSD+H +      PFR   P++IGHE AG V  +G+ VT  
Sbjct:  19 VPELKPNEVQIKVNVAGICGSDIHTY--KGLHPFR-KPPVVIGHEVAGEVVEVGSSVTKF  75

Query: 100 QVGDRVALEPGVPCLQCQRCREGRYN-----LCPNIKFFATPPVDGSLARYVCHPAAWCY 154
           +VGDRV +EP +   + +    G  N     L P +  +      G++A Y   P     
Sbjct:  76 KVGDRVTVEPQIGTGESEGVMTGNVNYSDTRLAPGMGDWL-----GTMAEYFASPEEQVI 130

Query: 155 RLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIV 214
           +LP+SVS ++G + EPL+V VHA  +        V +LGAGPIGLL  +  KA G   IV
Sbjct: 131 KLPDSVSYDQGVLVEPLAVGVHAAFKGDVQPTDRVAILGAGPIGLLTLIAVKAKGVKDIV 190

Query: 215 VTDIDDRRLAFAETHAGADAVINTRDLDE--HDAALVVQQALDGAQADIALDCAGLESTM 272
           VTD+ D  L  A+   GA  VIN +D     HDA    +Q+LD    D     AG+   +
Sbjct: 191 VTDVLDYSLQVAK-EMGASEVINIKDNSNWIHDA----KQSLDKGSFDKVFITAGVPGIV 245

Query: 273 RLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSN-TYPTCIALLASGRV 331
             +++++R GGR+  V M      V +      E +I G   Y+       + ++ASG++
Sbjct: 246 NDSLNLLRKGGRVVTVAMFHGQQSVDIEQLQQNEKEIIGCMTYNRPDTEEALEIIASGKL 305

Query: 332 NVKPLITHRF 341
           +V+ +I+H+ 
Sbjct: 306 DVEKVISHKL 315

ref|YP_153330.1| L-idonate 5-dehydrogenase [Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150]
gb|AAV80018.1| L-idonate 5-dehydrogenase [Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150]
(343 aa)

Score: 165 bits (418), Expect: 1.78055e-39
Length: 311, Idn/Pos/Gap = 105/158/25 (33%/50%/8%)

Query:  56 GICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQ 115
           GICGSD+HY+  G  G F +  PMI+GHE  G +  + +    L+ G  VA+ P  PC  
Sbjct:  38 GICGSDLHYYQEGKVGNFTVKAPMILGHEVIGKI--VHSDSDLLREGQPVAINPSKPCGH  95

Query: 116 CQRCREGRYNLCPNIKFFAT----PPVDGSLARYVCHPAAWCYRLPESVSLEEGAMCEPL 171
           C+ C +   N C  ++FF +    P VDG   R+     A C   PE    +  A  EPL
Sbjct:  96 CKYCLQHEENHCTEMRFFGSAMYFPHVDGGFTRFKAVDTAQCIPWPEQADEKAMAFAEPL 155

Query: 172 SVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAG 231
           +VA+HA   AG   G  V + G GPIG L     K  GA+ +V  DI  R L+ A    G
Sbjct: 156 AVAIHAAHEAGDLQGKRVFISGVGPIGCLIVSAVKTLGAAEVVCADISTRSLSLAR-QMG 214

Query: 232 ADAVINTRDLDEHDAALVVQQALDGAQA-----DIALDCAGLESTMRLAMHVVRPGGRIC 286
           AD ++N     +HD       +LDG +A     DI+ + +G  S++   + V R  G + 
Sbjct: 215 ADTLVNP----QHD-------SLDGWKAEKGYFDISFEVSGHPSSISTCLEVTRAKGVMV 263

Query: 287 LVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASGRVNVKPLIT--HRFMGL 344
            VGMG +  + P++   S+EI + G FR++  + T ++  A+  +N  PL++  + F  L
Sbjct: 264 QVGMGGAVPNFPMMMLISKEISLKGSFRFTTEFNTAVSWFANRVINPLPLLSAEYPFTDL 323

Query: 345 EESSLEAAFET 355
           E + + A  +T
Sbjct: 324 EAALIFAGDKT 334

ref|YP_049027.1| putative starvation sensing zinc-binding dehydrogenase [Erwinia carotovora subsp. atroseptica SCRI1043]
emb|CAG73830.1| putative starvation sensing zinc-binding dehydrogenase [Erwinia carotovora subsp. atroseptica SCRI1043]
(340 aa)

Score: 164 bits (414), Expect: 4.53317e-39
Length: 351, Idn/Pos/Gap = 112/176/20 (31%/50%/5%)

Query:  26 VLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVH-YWWHGSCGPFRLHDPMIIGHE  84
           V+ +P  L +  RS+P PA GEVR++++  GICGSD H Y  H    PF  + P +IGHE
Sbjct:   5 VIQQPNSLVIEERSIPQPAAGEVRVKVKLAGICGSDSHIYRGHN---PFAKY-PRVIGHE  60

Query:  85 SAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLAR 144
             GV+EA+G GV + ++G+RV+++P V C  C  C  G+ N+C ++        DG  + 
Sbjct:  61 FFGVIEAVGDGVDAARLGERVSVDPVVSCGHCYPCSIGKPNVCTSLVVLGVHR-DGGFSE 119

Query: 145 YVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMV 204
           Y    A   + +P+ +  E   M EP +++ +   +   T   + L+ GAGP+GL +  V
Sbjct: 120 YAAVSAKNAHVIPDEIPDEFAVMVEPFTISANVTAQVKPTEQDIALIYGAGPMGLTSVQV 179

Query: 205 AKA-FGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALD--GAQADI 261
            K  F    ++V D    RL  A   +GAD VIN       +A+L ++  L+    +  +
Sbjct: 180 LKGVFKVKEVIVVDRIPERLEMA-LRSGADRVIN-------NASLSLKDELETLNIKPTL 231

Query: 262 ALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPT 321
            +D A   S ++ A+ +  P  RI ++G  S    +     +S+EI IF     +N +P 
Sbjct: 232 IIDAACHPSILQEAITIASPAARIAIMGFSSEPCQISQQGITSKEISIFSSRLNANKFPI 291

Query: 322 CIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLTIPE 372
            I  L   R++   LITHRF   +   +  A E          KV+LT  E
Sbjct: 292 VIEWLKEKRIDPAKLITHRF---DYQQVVQAIEVFEKDQKRCCKVLLTFNE 339

gb|AAL23303.1| L-idonate 5-dehydrogenase [Salmonella typhimurium LT2]
ref|NP_463344.1| L-idonate 5-dehydrogenase [Salmonella typhimurium LT2]
(343 aa)

Score: 163 bits (413), Expect: 5.82253e-39
Length: 311, Idn/Pos/Gap = 104/158/25 (33%/50%/8%)

Query:  56 GICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQ 115
           GICGSD+HY+  G  G F +  PMI+GHE  G +  + +    L+ G  VA+ P  PC  
Sbjct:  38 GICGSDLHYYQEGKVGNFTVKAPMILGHEVIGKI--VHSDSDLLREGQPVAINPSEPCGH  95

Query: 116 CQRCREGRYNLCPNIKFFAT----PPVDGSLARYVCHPAAWCYRLPESVSLEEGAMCEPL 171
           C+ C +   N C  ++FF +    P VDG   R+     A C   PE    +  A  EPL
Sbjct:  96 CKYCLQHEENHCTEMRFFGSAMYFPHVDGGFTRFKAVDTAQCIPWPEQADEKAMAFAEPL 155

Query: 172 SVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAG 231
           +VA+HA   AG   G  + + G GPIG L     K  GA+ +V  DI  R L+ A    G
Sbjct: 156 AVAIHAAHEAGDLQGKRIFISGVGPIGCLIVSAVKTLGAAEVVCADISTRSLSLAR-QMG 214

Query: 232 ADAVINTRDLDEHDAALVVQQALDGAQA-----DIALDCAGLESTMRLAMHVVRPGGRIC 286
           AD ++N     +HD       +LD  +A     DI+ + +G  S++   + V R  G + 
Sbjct: 215 ADTLVNP----QHD-------SLDDWKAEKGYFDISFEVSGHPSSISTCLEVTRAKGVMV 263

Query: 287 LVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASGRVNVKPLIT--HRFMGL 344
            VGMG +  + P++   S+EI + G FR++  + T ++ LA+  +N  PL++  + F  L
Sbjct: 264 QVGMGGAVPNFPMMMVISKEISLKGSFRFTTEFNTAVSWLANRVINPLPLLSAEYPFTDL 323

Query: 345 EESSLEAAFET 355
           E + + A  +T
Sbjct: 324 EAALIFAGDKT 334

gb|EAA64202.1| hypothetical protein AN2158.2 [Aspergillus nidulans FGSC A4]
ref|XP_406295.1| hypothetical protein AN2158.2 [Aspergillus nidulans FGSC A4]
(353 aa)

Score: 163 bits (412), Expect: 9.06076e-39
Length: 348, Idn/Pos/Gap = 115/171/14 (33%/49%/4%)

Query:  31 RELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCG-PFRLHD------PMIIGH  83
           R++RV     P+ A G+V+++   VGICGSD+H +  G    P   H       P+ +GH
Sbjct:  10 RDIRVDQIDEPSCAEGQVKIRPAFVGICGSDLHEYLSGPIAIPTTPHPLTGAQLPVTLGH  69

Query:  84 ESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLA 143
           E +G +E +G GVT  +VGDRVA+ P +    C  C  GR N C ++ F       G L+
Sbjct:  70 EFSGTIEEVGQGVTGFKVGDRVAVRPNLSDGTCASCVYGRPNCCRSLGFIGFSSNSGGLS 129

Query: 144 RYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCM 203
            YV  PA     LPESV L+ GA+ EPL+VA HA  R+        LV+G GPIGL    
Sbjct: 130 DYVTVPAKHAILLPESVPLDLGALVEPLTVAWHAVARSPHETARTALVVGGGPIGLAVVQ 189

Query: 204 VAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIAL 263
           V KA G   +VV ++  +R  +A T  GA  V N       D    V+   D A ADI+ 
Sbjct: 190 VLKARGVQTVVVAEVSTQRREYALT-LGATHVFNPL---TDDVVARVRSLTDNAGADISF 245

Query: 264 DCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSN-TYPTC 322
           +C+G+++    AM+ +R  G   +V +      +   D  S E  + G     +  +   
Sbjct: 246 ECSGVQAGFDTAMNGIRVRGTTTIVSLWEKKPMIDAFDVVSYEKHVIGAAICDDGDFEAV 305

Query: 323 IALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLTI 370
           I  +  G++N +P+IT +     E   E  F+      +  VK+++ I
Sbjct: 306 IGAIKDGKLNPRPMITSKIR--MEDVEEKGFKALVDEKDKHVKILIDI 351

ref|ZP_00315363.1| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Microbulbifer degradans 2-40]
(338 aa)

Score: 162 bits (410), Expect: 1.44574e-38
Length: 297, Idn/Pos/Gap = 109/158/10 (36%/53%/3%)

Query:  43 PAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVG 102
           PA GEV LQ+   GICG+D+H + HG     R+  P IIGHE +G V  +GAGVT   VG
Sbjct:  22 PAEGEVCLQVGYTGICGTDMHIY-HGVMDQ-RVSIPQIIGHEMSGTVVEVGAGVTDYTVG  79

Query: 103 DRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPESVSL 162
           DRV + P   C  C  C  G  ++C N+KF       G+   Y    A   + LP++VSL
Sbjct:  80 DRVVVRPLDYCGDCPACNAGHSHVCHNLKFMGIDS-PGAFQSYWTVKARTLHALPDNVSL 138

Query: 163 EEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRR 222
           ++GA+ EPLSVA H   R     G   LV+G GPIG L  +VAK+ GA ++ ++++ + R
Sbjct: 139 KQGALIEPLSVACHDVARTRLQAGEKALVIGGGPIGQLVALVAKSVGAEVM-ISEVSEAR 197

Query: 223 LAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVVRPG 282
           L FA     A+  I T +    D   VV++   G  AD   + +G+ + +     V    
Sbjct: 198 LKFA-----AERGIKTVNPVTDDIEAVVKEWTGGKGADAVFEVSGVAAAVETMTKVAAVR 252

Query: 283 GRICLVGMGSSAMHVPLVDASSREIDIFGVFRY-SNTYPTCIALLASGRVNVKPLIT 338
           GRIC+V + S    V L     +E+++ G   Y S  +   I L+ASG+++V   I+
Sbjct: 253 GRICMVAIHSQKPQVDLFQFFWKELELLGARVYESADFEHAIELVASGKIDVDSFIS 309

ref|ZP_00200739.1| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Exiguobacterium sp. 255-15]
(363 aa)

Score: 161 bits (408), Expect: 2.46605e-38
Length: 329, Idn/Pos/Gap = 107/166/12 (32%/50%/3%)

Query:  39 SVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTS  98
           +VP+P  GEV +++    ICG+DVH +   +    R++ P + GHE +G V  LG G   
Sbjct:  36 AVPSPKRGEVLIRVEATSICGTDVHIYEWDAWAASRVNPPYVFGHEFSGEVVELGEGTKR  95

Query:  99 LQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPE 158
           L++GDRV+ E  + C QC++C  G+Y++C N K        G  A YV  P    +  PE
Sbjct:  96 LKLGDRVSAETHIVCHQCKQCLRGQYHICKNTKIIGV-DTQGCFAEYVVMPEENLWVNPE 154

Query: 159 SVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDI 218
            +     ++ EP+  AVH    A       V ++G GPIGL+   VAKA GA+ ++  D+
Sbjct: 155 DMPAAIASIQEPMGNAVH-TVLASDVSAKTVAIVGCGPIGLMAVSVAKAAGAAEVIAIDV 213

Query: 219 DDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHV 278
           +  RL  A+T  GAD VI++R     D    V+   DG   D+  + +G    +R A  +
Sbjct: 214 NPYRLELAKT-MGADVVIDSR---HEDVLERVRMMTDGDGIDVVCEMSGHPVAIRQAFEM 269

Query: 279 VRPGGRICLVGMGSSAMHVPLVD-ASSREIDIFGVF--RYSNTYPTCIALLASGRVNVKP 335
           V  GG + ++ +    + + L +    + + + G+   +   T+    A L+SG+V+VKP
Sbjct: 270 VTAGGDVNILSLPVKPVEIDLTNHVVFKGVRVQGITGRKMYETWSQVSAFLSSGKVDVKP 329

Query: 336 LITHRFMGLEESSLEAAFETARTAANGAV 364
           LITH    L     E  FE  R    G V
Sbjct: 330 LITHT---LPLERFEEGFELMRQGKCGKV 355

ref|YP_176838.1| sorbitol dehydrogenase [Bacillus clausii KSM-K16]
dbj|BAD65877.1| sorbitol dehydrogenase [Bacillus clausii KSM-K16]
(342 aa)

Score: 161 bits (408), Expect: 2.48671e-38
Length: 344, Idn/Pos/Gap = 114/177/21 (33%/51%/6%)

Query:  35 VMLRSVPAPAPGE--VRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEAL  92
           V L++ P PAPGE  V+++++  GICGSD+H +     G +++  P+ +GHE AG +  +
Sbjct:  14 VELQNKPEPAPGEKQVKIKVKYAGICGSDIHTYE----GHYKVAFPVTLGHEFAGEIVEV  69

Query:  93 GAGVTSLQVGDRVALEPGVP-CLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAA 151
           G GV S +VGDRV  E     C QC  C+   YNLC   K   T   DG  A YV     
Sbjct:  70 GPGVQSFKVGDRVTSETTFSICGQCPYCQTKDYNLCSERKGLGTQQ-DGGFAEYVLAREE 128

Query: 152 WCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGAS 211
             + LP++V     AM EPL+   HA  +     G L +V+G GPIGLL    AK+ GA 
Sbjct: 129 SLHLLPDNVDFRSAAMTEPLACTHHALAKTTINAGDLCVVIGPGPIGLLAAQAAKSKGAK 188

Query: 212 IIVVTDIDDRRLAFAETHA-GADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLES 270
           ++ +T ++  ++   +  A G D V+N    +E D   VV +  +G  AD+ L+C+G   
Sbjct: 189 VM-ITGLNHDKVRLEKARALGIDYVVNG---EETDVGEVVNELTNGYGADVVLECSGAVK 244

Query: 271 TMRLAMHVVRPGGRICLVGM-GSSAMHVPLVDASSREIDIFGV-FRYSNTYPTCIALLAS 328
                + ++R  G+   VG+  +S +   L     +EI + G   +    +   + LL +
Sbjct: 245 AANQGLKLLRKKGQYSQVGIFAASEIPFDLETIIQKEIHVIGSRSQKPADWEPSLMLLKT 304

Query: 329 GRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLTIPE 372
           G VN + L+TH +   E    E A++  ++    A+KV+L  PE
Sbjct: 305 GNVNARALVTHEY---ELHQWEEAYQAIKSGE--AIKVLLK-PE 342

gb|AAL20425.1| putative dehydrogenase [Salmonella typhimurium LT2]
ref|NP_460466.1| putative dehydrogenase [Salmonella typhimurium LT2]
(339 aa)

Score: 161 bits (407), Expect: 3.08916e-38
Length: 346, Idn/Pos/Gap = 104/173/16 (30%/50%/4%)

Query:  26 VLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVH-YWWHGSCGPFRLHDPMIIGHE  84
           V+ +P  L +  R++P PAPGEVR++++  GICGSD H Y  H    PF  + P +IGHE
Sbjct:   5 VIEKPNTLTIETRALPQPAPGEVRIKVKLAGICGSDSHIYRGHN---PFAKY-PRVIGHE  60

Query:  85 SAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLAR 144
             GV++A+G  V   ++G+RV+++P + C  C  C  G+ N+C ++        DG  + 
Sbjct:  61 FFGVIDAVGDNVNHDRIGERVSVDPVISCGHCYPCSVGKPNVCTSLVVLGVHR-DGGFSE 119

Query: 145 YVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMV 204
           Y   PA   +R+P++++     M EP ++A +   +   T   + L+ GAGP+GL     
Sbjct: 120 YAVAPARNAHRIPDNIADHHAVMVEPFTIAANVTGQVNPTEQDVALIYGAGPMGLTTVQA 179

Query: 205 AKA-FGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIAL 263
            K  +    ++V D  + RLA A+  +GAD  +N     +H  A  +QQ     +  + +
Sbjct: 180 LKGVYQVKTVIVVDRIEERLAMAK-QSGADWTLNN---GQHSLAEFLQQ--KALKPTLIV 233

Query: 264 DCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCI 323
           D A   + ++ A+ +  P  RI L+G  S    +     + +E+ I+     +N +P  I
Sbjct: 234 DAACHPAILQEAITLASPAARIVLMGFSSDPCEIVQQGITGKELAIYSSRLNANKFPVVI 293

Query: 324 ALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLT 369
             L  G ++   LITH F   +   +  A E          KV+LT
Sbjct: 294 DWLNKGLIDPDKLITHTF---DYQHVTDAIELFEKDQRQCCKVLLT 336

ref|ZP_00361018.1| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Polaromonas sp. JS666]
(349 aa)

Score: 160 bits (405), Expect: 6.17452e-38
Length: 314, Idn/Pos/Gap = 109/171/10 (34%/54%/3%)

Query:  30 PRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVV  89
           P +LR        P P E+ +++   GICGSD+HY+ HG  G  R+ +PM++GHE +G +
Sbjct:   9 PLDLRFDTFVSDQPGPTELGVRIAYGGICGSDLHYFQHGGFGTVRIREPMVLGHEVSGAI  68

Query:  90 EALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFAT----PPVDGSLARY 145
           E++G+ VT  QVG R+A+ P  PC  C+ C  G  N C  ++F+ +    P V G+   +
Sbjct:  69 ESVGSAVTQFQVGQRIAVSPSRPCGTCRYCNLGLQNHCMEMRFYGSAMRFPHVQGAFREH 128

Query: 146 VCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVA 205
           +   A+  + + + + L E A+ EPLSV +HA  RAG+  G  VLV G GPIGLL     
Sbjct: 129 LVIDASQAHLVADELPLAEAALAEPLSVGLHAITRAGSVFGKRVLVTGCGPIGLLLIAGL 188

Query: 206 KAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDC 265
           +  GA+ I+  DI D  L  A T  GAD  IN   L  H   L    AL+    ++  + 
Sbjct: 189 RRAGAAHIIAADIADVPLVCAAT-LGADETIN---LARHPGGL-APYALNKGMIEVMFEA 243

Query: 266 AGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIAL 325
           +G +  +R  + V+ P G + +VG+G   + VP+    ++E+D+ G FR+   +   +  
Sbjct: 244 SGSDKALRGGLDVMAPRGVVVIVGLGGD-ISVPMNLLVAKELDVRGTFRFHQEFAVAVRF 302

Query: 326 LASGRVNVKPLITH 339
           L    ++ +P+ITH
Sbjct: 303 LNQRLIDGRPVITH 316

ref|YP_177063.1| galactitol-1-phosphate 5-dehydrogenase [Bacillus clausii KSM-K16]
dbj|BAD66102.1| galactitol-1-phosphate 5-dehydrogenase [Bacillus clausii KSM-K16]
(352 aa)

Score: 159 bits (403), Expect: 1.01018e-37
Length: 342, Idn/Pos/Gap = 115/178/26 (33%/52%/7%)

Query:  41 PAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHD-PMIIGHESAGVVEALGAGVTSL  99
           P P   E  +++   GICGSD+  ++ G     ++H+ P+++GHE +G VEA+GA V S+
Sbjct:  20 PVPKEDEALIKVAYCGICGSDLARYFDG-----KVHNYPIVLGHEFSGTVEAVGASVDSV  74

Query: 100 QVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPES 159
            VGDRV + P +P       ++G   L  +  F  +   +G++A YV   A     LPE+
Sbjct:  75 AVGDRVVVAPLLPNKDDPFMQKGSPALSSSYSFLGSRE-NGAMAEYVVVKAENLLVLPET 133

Query: 160 VSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDID 219
           V+L E A+ EPL+VA+H   R     G  V VLGAG IG++  +  KA GA  +   DI+
Sbjct: 134 VTLAEAALIEPLTVAIHGIERIVLPAGEHVCVLGAGTIGIMTILALKARGAGKVTAIDIN 193

Query: 220 DRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVV 279
           D +LAFA+   GAD  IN+  L E   +   +    GA     ++ AG+ S+   A+ +V
Sbjct: 194 DEKLAFAKK-IGADDTINS--LKEDPVSYASKHGKPGA----VIETAGVPSSQEQAVALV 246

Query: 280 RPGGRICLVGMGSSAMHVPLVDASS---REIDIFGVF-RYSNTYP-----TCIALLASGR 330
              G+I  VG  S  +  P          E++I G +  YS  +P       I  +ASG+
Sbjct: 247 EKKGKIVFVGTASGDVTFPAATFEKILREELEITGSWMSYSGPFPGYEWQAAIDYIASGK 306

Query: 331 VNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLTIPE 372
           ++VKPLI H    LE+   +  F+  +   N ++K++  I E
Sbjct: 307 IDVKPLI-HDVFKLEDG--DKPFQAMKDPDNHSIKLLYQIAE 345

ref|YP_150606.1| putative dehydrogenase [Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150]
gb|AAV77294.1| putative dehydrogenase [Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150]
(339 aa)

Score: 159 bits (402), Expect: 1.22389e-37
Length: 318, Idn/Pos/Gap = 98/163/13 (30%/51%/4%)

Query:  26 VLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVH-YWWHGSCGPFRLHDPMIIGHE  84
           V+ +P  L +  R++P PAPGEVR++++  GICGSD H Y  H    PF  + P +IGHE
Sbjct:   5 VIEKPNTLTIETRALPQPAPGEVRIKVKLAGICGSDSHIYRGHN---PFAKY-PRVIGHE  60

Query:  85 SAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLAR 144
             GV++A+G  V   ++G+RV+++P + C  C  C  G+ N+C ++        DG  + 
Sbjct:  61 FFGVIDAVGDNVNRDRIGERVSVDPVISCGHCYPCSVGKPNVCTSLVVLGVHR-DGGFSE 119

Query: 145 YVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMV 204
           Y   PA   +R+P++++     M EP ++A +   +   T   + L+ GAGP+GL     
Sbjct: 120 YAVAPARNAHRIPDNIADHHAVMVEPFTIAANVTGQVNPTEQDVALIYGAGPMGLTTVQA 179

Query: 205 AKA-FGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIAL 263
            K  +    ++V D  + RLA A+  +GAD  +N     +H  A  +QQ     +  + +
Sbjct: 180 LKGVYQVKTVIVVDRIEERLAMAK-QSGADWSLNN---GQHSLAEFLQQ--KALKPTLIV 233

Query: 264 DCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCI 323
           D A   + ++ A+ +  P  RI L+G  S    +     + +E+ I+      N +P  I
Sbjct: 234 DAACHPAILQEAITLASPAARIVLMGFSSDPCEIVQQGITGKELAIYSSRLNVNKFPVVI 293

Query: 324 ALLASGRVNVKPLITHRF 341
             L  G ++   LITH F
Sbjct: 294 DWLNKGLIDPDKLITHTF 311

ref|ZP_00320055.1| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Oenococcus oeni PSU-1]
(360 aa)

Score: 159 bits (401), Expect: 1.55893e-37
Length: 331, Idn/Pos/Gap = 98/169/21 (29%/51%/6%)

Query:  25 GVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHG---SCGPF---RLHDP  78
            V+  P+++R   R++P PAP EV++++   GICGSD+H +  G   +  P     +  P
Sbjct:   7 AVIYGPKDIRFEKRNIPDPAPDEVQIEVAFNGICGSDIHEYLEGMDLATMPHPLTHMQAP  66

Query:  79 MIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNI------KF 132
           +I GHE +G +  +G  V+ L++GD+VA+EP + C +C  C  G YN C +         
Sbjct:  67 LIPGHEFSGTISKIGKQVSKLRIGDKVAVEPMIACGKCPECLSGHYNWCEHAIGSDQSAG 126

Query: 133 FATPPVDGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVL 192
           F     +G LA      + + + LP    L+ GA+ EP+SVA  A   +  + G  VL+ 
Sbjct: 127 FLGFSANGGLAEKCNVKSTFAHLLPTDFPLDLGALVEPVSVAAQAVMASRVSPGDDVLIQ 186

Query: 193 GAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQ 252
           GAGPIGL   ++A+  GA  +++ D+ + RL  A    G    I  R   +   A  +  
Sbjct: 187 GAGPIGLFTALIAQISGAHHVIINDMSEERLDLA-NELGVQYPI--RADSQKSLAHAIST 243

Query: 253 ALDGAQADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASS---REIDI 309
             +    D+A DCAG++ T+  A+  ++ GG++ ++ +     H P+VD  +   +   +
Sbjct: 244 ITENQGVDVAFDCAGVQPTLTGAIQALKNGGKVTVIAL---FQHPPVVDVRALLKKGGSL 300

Query: 310 FGVFRYSNTYPTCIALLASGRVNVKPLITHR 340
              + Y+N +   I ++ + R   K +IT +
Sbjct: 301 LTSYGYANIFDRVIKIIDTYRSLFKRVITKK 331

ref|YP_174130.1| Zn-dependent alcohol dehydrogenase [Bacillus clausii KSM-K16]
dbj|BAD63169.1| Zn-dependent alcohol dehydrogenase [Bacillus clausii KSM-K16]
(345 aa)

Score: 158 bits (400), Expect: 2.14055e-37
Length: 295, Idn/Pos/Gap = 94/160/9 (31%/54%/3%)

Query:  47 EVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGDRVA 106
           +V ++++ VGICGSD+H + HGS  PF ++ P IIGHE  G+VE +G+GV  L+ GDRVA
Sbjct:  27 DVLVKVQAVGICGSDMHIY-HGS-NPFTVY-PRIIGHEVGGIVEEVGSGVHGLRRGDRVA  83

Query: 107 LEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPESVSLEEGA 166
           LEP   C  C  C++GR N+C  ++ F     DG +  ++  P A  +++   +  E  A
Sbjct:  84 LEPISSCGVCYACKKGRPNVCAKLEVFGVHR-DGGMREWMVAPEANWHKVNGDLPFEAAA 142

Query: 167 MCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFA 226
           + EP+++   A  R     G  V ++GAGP G+   ++AK  GA++  ++D+   RL +A
Sbjct: 143 LVEPMTIGAQAAYRGNIEPGDTVFIMGAGPTGIACLIMAKQKGATVF-ISDLQANRLDYA 201

Query: 227 ETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVVRPGGRIC 286
           +   GAD  I+   L       V+ +  DG  A++ +D  G  +T   A+ +    G + 
Sbjct: 202 K-QVGADFTIH---LPHEKPEAVLFEKTDGEFANVVIDAVGTSTTFAEAVKLASVAGTVV 257

Query: 287 LVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASGRVNVKPLITHRF 341
            +G   +   +P +  + +E+ + G    +N +P  I  +   +V+   +I+HRF
Sbjct: 258 TLGFNETPSDIPSLLLTKKELTVAGSRLQTNQFPDVIRQVNEQKVDPASIISHRF 312

ref|YP_216510.1| putative dehydrogenase [Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67]
gb|AAX65429.1| putative dehydrogenase [Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67]
(339 aa)

Score: 158 bits (400), Expect: 2.36597e-37
Length: 346, Idn/Pos/Gap = 103/172/16 (29%/49%/4%)

Query:  26 VLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVH-YWWHGSCGPFRLHDPMIIGHE  84
           V+ +P  L +  R++P PAPGEVR++++  GICGSD H Y  H    PF  + P +IGHE
Sbjct:   5 VIEKPNTLTIETRALPQPAPGEVRIKVKLAGICGSDSHIYRGHN---PFAKY-PRVIGHE  60

Query:  85 SAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLAR 144
             GV++A+G  V   ++G+RV+++P + C  C  C  G+ N+C ++        DG  + 
Sbjct:  61 FFGVIDAVGDNVNHDRIGERVSVDPVISCGHCYPCSVGKPNVCTSLVVLGVHR-DGGFSE 119

Query: 145 YVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMV 204
           Y   PA   +R+P++++     M EP ++A +   +   T   + L+ GAGP+GL     
Sbjct: 120 YAVAPARNAHRIPDNIADHHAVMVEPFTIAANVTGQVNPTEQDVALIYGAGPMGLTTVQA 179

Query: 205 AKA-FGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIAL 263
            K  +    ++V D  + RLA A+  +GAD  +N     +H  A  +QQ     +  + +
Sbjct: 180 LKGVYQVKTVIVVDRIEERLAMAK-QSGADWTLNN---GQHSLAEFLQQ--KALKPTLIV 233

Query: 264 DCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCI 323
           D A   + ++ A+ +     RI L+   S    +   D + +E+ I+     +N +P  I
Sbjct: 234 DAACHPAILQEAITLASSAARIVLMRFSSDPCEIVQQDITGKELAIYSSRLNANKFPVVI 293

Query: 324 ALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLT 369
             L  G ++   LITH F   +   +  A E          KV+LT
Sbjct: 294 DWLNKGLIDPDKLITHTF---DYQHVTDAIELFEKDQRQCCKVLLT 336

emb|CAB46780.1| putative zinc-binding alcohol dehydrogenase [Streptomyces coelicolor A3(2)]
ref|NP_625956.1| putative zinc-binding alcohol dehydrogenase [Streptomyces coelicolor A3(2)]
pir||T36783 probable zinc-binding alcohol dehydrogenase - Streptomyces coelicolor
(358 aa)

Score: 158 bits (399), Expect: 3.03892e-37
Length: 324, Idn/Pos/Gap = 121/168/20 (37%/51%/6%)

Query:  13 AGSVLNEKANPCGVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGP  72
           AG  + E+  P  V+    +LRV    V  P PGE  + +R  G+CGSD+HYW HG  G 
Sbjct:   3 AGERVPEEFVPGCVIHGAGDLRVTDVPVRPPGPGEALVAVRYGGVCGSDLHYWRHGGVGD  62

Query:  73 FRLHDPMIIGHESAGVVEALGAGVT-SLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIK 131
           F L +PM++GHE  G V A G+  T     G  VA+ P  PC  C  C + R N+C + +
Sbjct:  63 FHLREPMLLGHEVVGTVVAYGSPDTPGPAAGTSVAVHPATPCGVCPECVDRRRNVCRDTR 122

Query: 132 FFAT----PPVDGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGS 187
           +  +    P V G  A  +  PA     LP  +     A+ EPLSVA+HA RRAG   G 
Sbjct: 123 YLGSAARFPHVQGGFAARIVVPAGQLRPLPAGLDPRRAALAEPLSVALHAVRRAGDPAGR 182

Query: 188 LVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAA 247
            VLV GAGPIG L    AKA GA+ + VTD+    L +A   AGAD ++   D D  DA 
Sbjct: 183 HVLVTGAGPIGCLVVAAAKAAGAAHVTVTDLLPAALEYARA-AGADTLVRADDPD--DAG 239

Query: 248 LVVQQALDGAQADIALDCAGLESTMRLAMHVVRPGGRICLVGM---GSSAMHVPLVDASS 304
             V       + D A++ +G+ + +   + +VR GG +  +GM   G S     L+   S
Sbjct: 240 WPV-------EVDTAVEASGVAAGLDTCLRLVRRGGVVVQLGMLPPGQSPFAGNLL--VS 290

Query: 305 REIDIFGVFRYSNTYPTCIALLAS 328
           REI++ G FR+   +   + LLA+
Sbjct: 291 REIELRGAFRFDGEFDDALRLLAA 314

gb|AAB70823.1| benzyl alcohol dehydrogenase [Pseudomonas putida]
(348 aa)

Score: 157 bits (398), Expect: 3.77515e-37
Length: 314, Idn/Pos/Gap = 109/167/15 (34%/53%/4%)

Query:  47 EVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGDRVA 106
           +V +++   GICG+D+  +  G     R+  P I+GHE +GV+E +G+ V  L+ G RV+
Sbjct:  29 DVLVKVEAAGICGTDLLIYKWGEFAK-RMKLPTILGHEVSGVIEQVGSDVKGLRPGMRVS  87

Query: 107 LEPGVPCLQCQRCREGRYNLCPNIKFFATPPVD--GSLARYVCHPAAWCYRLPESVSLEE 164
           LE  +PC  C  CR G  ++CPN ++   P VD  G  A +V  P + C+ +P  +   +
Sbjct:  88 LESHLPCGTCYTCRRGWAHVCPNTRY---PGVDFDGGFASFVVVPESVCWPVPCGIPPLQ 144

Query: 165 GAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLA 224
            AM EP  +AVHA+       G  VLV G GPIGL+N   AKA GAS ++ TDI   RL 
Sbjct: 145 AAMMEPFGLAVHASLEGSGVSGLNVLVSGCGPIGLMNIAAAKALGASKVIATDIHPLRLT 204

Query: 225 FAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVVRPGGR 284
            A    GAD  IN     E      V+  L     D+A+D +G  + ++  +  +  GG 
Sbjct: 205 -AAAKMGADECINA---TEESVYKTVRSLLGERGVDVAIDYSGQAAALKELIQSITHGGE 260

Query: 285 ICLVGMGSSAMHVPLVDASSREIDIFGVF--RYSNTYPTCIALLASGRVNVKPLITHRFM 342
           + L+G+ S  + + L +   + + + G+   R   T+    +LL +GRV++  L++HR  
Sbjct: 261 LRLMGVPSHDILLNLEEWLFKGLIVRGLHGRRLFETWERSTSLLVTGRVDLSSLVSHR-- 318

Query: 343 GLEESSLEAAFETA 356
            L  S+ E AFE A
Sbjct: 319 -LPLSAAEDAFEMA 331

gb|AAA84986.1| TmbW
(348 aa)

Score: 157 bits (398), Expect: 4.10365e-37
Length: 314, Idn/Pos/Gap = 109/167/15 (34%/53%/4%)

Query:  47 EVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGDRVA 106
           +V +++   GICG+D+  +  G     R+  P I+GHE +GV+E +G+ V  L+ G RV+
Sbjct:  29 DVLVKVEAAGICGTDLLIYKWGEFAK-RMKLPTILGHEVSGVIEQVGSDVKGLRPGMRVS  87

Query: 107 LEPGVPCLQCQRCREGRYNLCPNIKFFATPPVD--GSLARYVCHPAAWCYRLPESVSLEE 164
           LE  +PC  C  CR G  ++CPN ++   P VD  G  A +V  P + C+ +P  +   +
Sbjct:  88 LESHLPCGTCYTCRRGWAHVCPNTRY---PGVDFDGGFASFVVVPESVCWPVPCGIPPLQ 144

Query: 165 GAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLA 224
            AM EP  +AVHA+       G  VLV G GPIGL+N   AKA GAS ++ TDI   RL 
Sbjct: 145 AAMMEPFGLAVHASLEGSGVSGLNVLVSGCGPIGLMNIAAAKALGASKVIATDIHPLRLT 204

Query: 225 FAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVVRPGGR 284
            A    GAD  IN     E      V+  L     D+A+D +G  + ++  +  +  GG 
Sbjct: 205 -AAAKMGADECINA---TEESVYKTVRSLLGERGVDVAIDYSGQAAALKELIQSITHGGE 260

Query: 285 ICLVGMGSSAMHVPLVDASSREIDIFGVF--RYSNTYPTCIALLASGRVNVKPLITHRFM 342
           + L+G+ S  + + L +   + + + G+   R   T+    +LL +GRV++  L++HR  
Sbjct: 261 LRLMGVPSHDILLNLEEWLFKGLIVRGLHGRRLFETWERSTSLLVTGRVDLSSLVSHR-- 318

Query: 343 GLEESSLEAAFETA 356
            L  S+ E AFE A
Sbjct: 319 -LPLSAAEDAFEMA 331

ref|ZP_00132850.2| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Haemophilus somnus 2336]
(359 aa)

Score: 157 bits (396), Expect: 5.44972e-37
Length: 304, Idn/Pos/Gap = 99/150/16 (32%/49%/5%)

Query:  57 ICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQC 116
           ICGSD+HY+ HG  G F +  PMI+GHE  G +    A   +L  G +VA+ P  PCL C
Sbjct:  54 ICGSDLHYYEHGKVGNFAIKHPMILGHEIIGKIVKTNA--PNLFEGQKVAINPSKPCLSC 111

Query: 117 QRCREGRYNLCPNIKFFAT----PPVDGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLS 172
             C  G  N C  ++FF +    P VDG   +Y       C    + VS E     EPL+
Sbjct: 112 AYCLSGYSNQCETMRFFGSAMYNPHVDGGFTQYKIVDNNQCIPYSQEVSDEVMVFAEPLA 171

Query: 173 VAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGA 232
           V +HA ++ G   G  V + G GPIG L     KA GA+ I+ +DI  R L  A    GA
Sbjct: 172 VTIHAAKQGGDLQGKKVFISGVGPIGCLAVAAVKALGAAEIICSDISQRCLDLA-LEMGA 230

Query: 233 DAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVVRPGGRICLVGMGS 292
             V++     E + +  +Q   +  + D++ + +G  S++   + V +  G I  +GMG 
Sbjct: 231 TKVLHA---TEGNFSEYLQ---NKGEFDVSFEASGHISSIERCLAVTKAKGTIVQIGMGG 284

Query: 293 SAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASGRVNVKPLITHRFMGLEESSLEAA 352
           S     ++   S+EI+  G FR+   + T +  L+ G++N  PL++  +       LE A
Sbjct: 285 SIPQFNMMPLISKEINWKGSFRFVEEFNTAVKWLSLGKINPLPLLSEIY---PFEQLETA 341

Query: 353 FETA 356
            + A
Sbjct: 342 LQRA 345

ref|YP_177572.1| sorbitol dehydrogenase [Bacillus clausii KSM-K16]
dbj|BAD66611.1| sorbitol dehydrogenase [Bacillus clausii KSM-K16]
(344 aa)

Score: 157 bits (396), Expect: 5.87472e-37
Length: 339, Idn/Pos/Gap = 113/171/21 (33%/50%/6%)

Query:  40 VPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSL  99
           +P     +V +++   GICGSD+H +      PFR   P++IGHE AG V ++G  V  +
Sbjct:  19 IPVVKDNDVLIKVAVAGICGSDIHTY--KGLHPFR-KPPVVIGHEVAGEVVSVGQAVKRV  75

Query: 100 QVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVD--GSLARYVCHPAAWCYRLP 157
           QVGDRV +EP +   + +    G+ NL    K  A    D  G++A Y   P A   +LP
Sbjct:  76 QVGDRVTVEPQIGTGESEGVMTGQANLSD--KRLAPGMGDWLGTMAEYFVSPEAQVIKLP 133

Query: 158 ESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTD 217
           ++VS E+G + EPL+V VHA R+ G   G  V +LGAGPIGLL  M  KA GAS +VVTD
Sbjct: 134 DAVSYEKGVLVEPLAVGVHAARKGGIQPGDRVAILGAGPIGLLTLMAVKAKGASHVVVTD 193

Query: 218 IDDRRLAFAETHAGADAVINTR---DLDEHDAALVVQQALDGAQADIALDCAGLESTMRL 274
           + D  L  A+   GA A IN +   D  E   + V      G   D  L  AG+   +  
Sbjct: 194 VLDYSLDVAK-QMGATAAINIKGKPDWIEEAKSKV------GRSFDKVLITAGVPGIIND 246

Query: 275 AMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSN-TYPTCIALLASGRVNV 333
           ++++++ GGR   V M        +      E +I G   Y+       + ++A G + V
Sbjct: 247 SLNLLKKGGRAVTVAMFHGQQDFDVEQLQQNEKEIVGCMTYNRPDTEEALDIIAKGALPV 306

Query: 334 KPLITHRFMGLEESSLEAAFETARTAANGAVKVMLTIPE 372
           + +I+H+   L     +  FE      + +VKV+++  +
Sbjct: 307 EKVISHQ---LSYEQADKGFEMVDKKQDNSVKVIVSFEQ 342

dbj|BAB03908.1| sorbitol dehydrogenase [Bacillus halodurans C-125]
sp|Q9Z9U1|DHSO_BACHD Sorbitol dehydrogenase (L-iditol 2-dehydrogenase) (Glucitol dehydrogenase)
ref|NP_241055.1| sorbitol dehydrogenase [Bacillus halodurans C-125]
dbj|BAA75341.1| sorbitol dehydrogenase [Bacillus halodurans]
(343 aa)

Score: 157 bits (396), Expect: 6.17631e-37
Length: 334, Idn/Pos/Gap = 105/165/18 (31%/49%/5%)

Query:  41 PAPAPG--EVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTS  98
           P P PG  +V+++++  G+CGSD+H +     G + +  P+ +GHE +G +  LG GVT 
Sbjct:  20 PEPTPGKHQVKIKVKYTGVCGSDIHTYE----GHYPVAAPVTLGHEFSGEIVELGEGVTG  75

Query:  99 LQVGDRVALEPGVP-CLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLP 157
             VGDRV  E     C +C  C  G YNLC + K       DGS A+YV       + LP
Sbjct:  76 FNVGDRVTSETTYSICGKCSYCTSGDYNLCSHRKGLGNQQ-DGSFAKYVIARQESLHHLP 134

Query: 158 ESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTD 217
             V     AM EPL+   HA  +     G LV+V G GPIGLL   VAK+ G ++I+   
Sbjct: 135 AGVDDRSAAMTEPLACTHHAIAKTSINKGDLVVVTGPGPIGLLAAQVAKSHGGTVIITGL 194

Query: 218 IDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMH 277
            +D+         G D  I+T+++D  +   +V +  DG  AD+ L+C+G     +  + 
Sbjct: 195 SNDQVRLKKAKEVGIDYAIDTQEVDIKE---LVSELTDGYGADVVLECSGAVPAAKQGID 251

Query: 278 VVRPGGRICLVGM-GSSAMHVPLVDASSREIDIFGV-FRYSNTYPTCIALLASGRVNVKP 335
           ++R  G+   VG+     +         +EI + G   +    +   ++LL   +VN K 
Sbjct: 252 LLRKKGQYAQVGLFAQPEIQFNFEKIIQKEISVVGSRSQKPADWEPALSLLNEKKVNAKT 311

Query: 336 LITHRFMGLEESSLEAAFETARTAANGAVKVMLT 369
           L+TH +     S  + A+   ++    A+KV+LT
Sbjct: 312 LVTHEYT---ISEWDKAYHAIKSGE--AIKVLLT 340

gb|AAK88710.1| AGR_L_281p [Agrobacterium tumefaciens str. C58]
pir||D98148 (R,R)-butanediol dehydrogenase (EC 1.1.1.4) [imported] - Agrobacterium tumefaciens (strain C58, Cereon)
ref|NP_355925.1| hypothetical protein AGR_L_281 [Agrobacterium tumefaciens str. C58]
(397 aa)

Score: 156 bits (395), Expect: 7.11756e-37
Length: 351, Idn/Pos/Gap = 111/182/16 (31%/51%/4%)

Query:  31 RELRVMLRSVPA-PAPGEVRLQMRCVGICGSDVHYWWHGSC------GPFR-LHDPMIIG  82
           ++LR+   + P  P PG+V ++ R VGICG+D+H + +G         PF   H P I+G
Sbjct:  50 KDLRIEDIAEPKRPGPGQVLVRNRFVGICGTDLHEYSYGPIFIPTEPHPFTGAHGPQILG 109

Query:  83 HESAGVVEALGAGVTSLQVGDRVALEPGV-PCLQCQRCREGRYNLCPNIKFFATPPVDGS 141
           HE  GVVEA+G GVTS+ VGDRV+++P + P         G ++L   +         G 
Sbjct: 110 HEFGGVVEAIGDGVTSVNVGDRVSIQPLIMPRSGDYFADRGLFHLSTQLALVGLSWDGGG 169

Query: 142 LARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLN 201
           +A           ++P+ ++ EE A+ EP +VAV+A  R G T G+ VLV GAGPIG+L 
Sbjct: 170 MAEAALVNEYNVQKIPDEMTDEEAALVEPSAVAVYACDRGGVTAGNSVLVTGAGPIGMLT 229

Query: 202 CMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDG-AQAD 260
            + A+A GA+ + V+D++D RL  A         IN +  +  D   VV+ A +G    D
Sbjct: 230 LLAARAAGATQLFVSDLNDARLELARNVIRDVITINPKRDNVGD---VVRSATEGKVGCD 286

Query: 261 IALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTY- 319
           +A++C G E  ++  +  VR  G +   G+      +     + R+++I G + Y   Y 
Sbjct: 287 VAIECVGNEHALKACVDAVRKQGVVVQTGLHPHENPIDWFQVTFRDLEIKGSWAYPTHYW 346

Query: 320 PTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLTI 370
           P  I L+ASG +    ++T R     ++++   F+     A   +K+++ +
Sbjct: 347 PRVIRLIASGLLPATKIVTKRIT--LDTAVTEGFDALLDPAGTHLKILIDL 395

ref|NP_535218.1| zinc-binding dehydrogenase [Agrobacterium tumefaciens str. C58]
gb|AAL45534.1| zinc-binding dehydrogenase [Agrobacterium tumefaciens str. C58]
pir||AH3139 zinc-binding dehydrogenase Atu4740 [imported] - Agrobacterium tumefaciens (strain C58, Dupont)
(357 aa)

Score: 156 bits (394), Expect: 1.03608e-36
Length: 351, Idn/Pos/Gap = 111/182/16 (31%/51%/4%)

Query:  31 RELRVMLRSVPA-PAPGEVRLQMRCVGICGSDVHYWWHGSC------GPFR-LHDPMIIG  82
           ++LR+   + P  P PG+V ++ R VGICG+D+H + +G         PF   H P I+G
Sbjct:  10 KDLRIEDIAEPKRPGPGQVLVRNRFVGICGTDLHEYSYGPIFIPTEPHPFTGAHGPQILG  69

Query:  83 HESAGVVEALGAGVTSLQVGDRVALEPGV-PCLQCQRCREGRYNLCPNIKFFATPPVDGS 141
           HE  GVVEA+G GVTS+ VGDRV+++P + P         G ++L   +         G 
Sbjct:  70 HEFGGVVEAIGDGVTSVNVGDRVSIQPLIMPRSGDYFADRGLFHLSTQLALVGLSWDGGG 129

Query: 142 LARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLN 201
           +A           ++P+ ++ EE A+ EP +VAV+A  R G T G+ VLV GAGPIG+L 
Sbjct: 130 MAEAALVNEYNVQKIPDEMTDEEAALVEPSAVAVYACDRGGVTAGNSVLVTGAGPIGMLT 189

Query: 202 CMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDG-AQAD 260
            + A+A GA+ + V+D++D RL  A         IN +  +  D   VV+ A +G    D
Sbjct: 190 LLAARAAGATQLFVSDLNDARLELARNVIRDVITINPKRDNVGD---VVRSATEGKVGCD 246

Query: 261 IALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTY- 319
           +A++C G E  ++  +  VR  G +   G+      +     + R+++I G + Y   Y 
Sbjct: 247 VAIECVGNEHALKACVDAVRKQGVVVQTGLHPHENPIDWFQVTFRDLEIKGSWAYPTHYW 306

Query: 320 PTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLTI 370
           P  I L+ASG +    ++T R     ++++   F+     A   +K+++ +
Sbjct: 307 PRVIRLIASGLLPATKIVTKRIT--LDTAVTEGFDALLDPAGTHLKILIDL 355

gb|AAC38358.1| putative alcohol dehydrogenase NtnW [Pseudomonas sp. TW3]
(348 aa)

Score: 155 bits (392), Expect: 1.92108e-36
Length: 314, Idn/Pos/Gap = 108/166/15 (34%/52%/4%)

Query:  47 EVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGDRVA 106
           +V +++   GICG+D+  +  G     R+  P I+GHE +GV+E +G+ V  L+ G RV+
Sbjct:  29 DVLVKVEAAGICGTDLLIYKWGEFAK-RMKLPTILGHEVSGVIEQVGSDVKGLRPGMRVS  87

Query: 107 LEPGVPCLQCQRCREGRYNLCPNIKFFATPPVD--GSLARYVCHPAAWCYRLPESVSLEE 164
           LE  +PC  C  CR G  ++CP  ++   P VD  G  A +V  P + C+ +P  +   +
Sbjct:  88 LESHLPCGTCYTCRRGWAHVCPKTRY---PGVDFDGGFASFVVVPESVCWPVPCGIPPLQ 144

Query: 165 GAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLA 224
            AM EP  +AVHA+       G  VLV G GPIGL+N   AKA GAS ++ TDI   RL 
Sbjct: 145 AAMMEPFGLAVHASLEGSGVSGLNVLVSGCGPIGLMNIAAAKALGASKVIATDIHPLRLT 204

Query: 225 FAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVVRPGGR 284
            A    GAD  IN     E      V+  L     D+A+D +G  + ++  +  +  GG 
Sbjct: 205 -AAAKMGADECINAA---EESVYKTVRSLLGERGVDVAIDYSGQAAALKELIQSITHGGE 260

Query: 285 ICLVGMGSSAMHVPLVDASSREIDIFGVF--RYSNTYPTCIALLASGRVNVKPLITHRFM 342
           + L+G+ S  + + L +   + + + G+   R   T+    +LL +GRV++  L++HR  
Sbjct: 261 LRLMGVPSHDILLNLEEWLFKGLIVRGLHGRRLYETWERSTSLLVTGRVDLSSLVSHR-- 318

Query: 343 GLEESSLEAAFETA 356
            L  S+ E AFE A
Sbjct: 319 -LPLSAAEDAFEMA 331

ref|NP_650856.2| CG4836-PC, isoform C [Drosophila melanogaster]
gb|AAF55731.2| CG4836-PC, isoform C [Drosophila melanogaster]
(1217 aa)

Score: 154 bits (389), Expect: 3.83979e-36
Length: 357, Idn/Pos/Gap = 112/177/35 (31%/49%/9%)

Query:   27 LVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESA   86
            +  P E+ V+  S P P   +V ++   V +  SD+H + +G+    R  + M +GH++ 
Sbjct:  881 ITNPYEISVVPFSKPRPKDFDVLIRTGSVAVSNSDIHVYENGN----RDMEAMSLGHDAT  936

Query:   87 GVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYV  146
            G+VE LG  V  L VGDRV +E  + C  C  C++G YN+C  + +      +G L+ Y 
Sbjct:  937 GIVEELGRCVQHLHVGDRVVMESALSCGICDLCKKGLYNMCSGLVY------NGFLSTYQ  990

Query:  147 CHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAK  206
             HPA  C+RLPES+S+E GA+ + L++   A  +A  T  S VL+LGA P  +   + AK
Sbjct:  991 THPADLCHRLPESISMEAGALTQTLALGCQACFKANVTPTSNVLILGACPTAVAAGICAK 1050

Query:  207 AFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLD----EHDAALVVQQALDGAQA---  259
            A GA          +R+A A   A A  V+  RD      E D+  +  + L+   +   
Sbjct: 1051 AIGA----------KRVAIAGCMAPALDVV-ARDFGFQAVEFDSNALFGEVLEAIYSKFR 1099

Query:  260 ---DIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYS  316
               D  ++C+    TM LA+  ++P G   L    S       +D   + I +   FR +
Sbjct: 1100 DWPDCVINCSISAMTMNLAVMALQPCGVCVLAECDSECASFNALDVLMKNIRLVPSFRSA 1159

Query:  317 NTYPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAAN-GAVKVMLTIPE  372
            N YPT + L+ SGR +++  IT  +     S  + AF  A+  +N G  KV++   E
Sbjct: 1160 NMYPTALQLMQSGRAHMQKFITATY---PLSKADEAFRAAQHESNIGLGKVIVNCAE 1213

ref|NP_732476.2| CG4836-PB, isoform B [Drosophila melanogaster]
gb|AAN13816.2| CG4836-PB, isoform B [Drosophila melanogaster]
(1214 aa)

Score: 154 bits (389), Expect: 3.93711e-36
Length: 357, Idn/Pos/Gap = 112/177/35 (31%/49%/9%)

Query:   27 LVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESA   86
            +  P E+ V+  S P P   +V ++   V +  SD+H + +G+    R  + M +GH++ 
Sbjct:  878 ITNPYEISVVPFSKPRPKDFDVLIRTGSVAVSNSDIHVYENGN----RDMEAMSLGHDAT  933

Query:   87 GVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYV  146
            G+VE LG  V  L VGDRV +E  + C  C  C++G YN+C  + +      +G L+ Y 
Sbjct:  934 GIVEELGRCVQHLHVGDRVVMESALSCGICDLCKKGLYNMCSGLVY------NGFLSTYQ  987

Query:  147 CHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAK  206
             HPA  C+RLPES+S+E GA+ + L++   A  +A  T  S VL+LGA P  +   + AK
Sbjct:  988 THPADLCHRLPESISMEAGALTQTLALGCQACFKANVTPTSNVLILGACPTAVAAGICAK 1047

Query:  207 AFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLD----EHDAALVVQQALDGAQA---  259
            A GA          +R+A A   A A  V+  RD      E D+  +  + L+   +   
Sbjct: 1048 AIGA----------KRVAIAGCMAPALDVV-ARDFGFQAVEFDSNALFGEVLEAIYSKFR 1096

Query:  260 ---DIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYS  316
               D  ++C+    TM LA+  ++P G   L    S       +D   + I +   FR +
Sbjct: 1097 DWPDCVINCSISAMTMNLAVMALQPCGVCVLAECDSECASFNALDVLMKNIRLVPSFRSA 1156

Query:  317 NTYPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAAN-GAVKVMLTIPE  372
            N YPT + L+ SGR +++  IT  +     S  + AF  A+  +N G  KV++   E
Sbjct: 1157 NMYPTALQLMQSGRAHMQKFITATY---PLSKADEAFRAAQHESNIGLGKVIVNCAE 1210

gb|AAC44788.1| XylW hypothetical protein
(348 aa)

Score: 154 bits (388), Expect: 4.61347e-36
Length: 314, Idn/Pos/Gap = 107/165/15 (34%/52%/4%)

Query:  47 EVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGDRVA 106
           +V +++   GICG+D+  +  G     R+  P I+GHE +GV+E +G+ V  L+ G RV+
Sbjct:  29 DVLVKVEAAGICGTDLLIYKWGEFAK-RMKLPTILGHEVSGVIEQVGSDVKGLRPGMRVS  87

Query: 107 LEPGVPCLQCQRCREGRYNLCPNIKFFATPPVD--GSLARYVCHPAAWCYRLPESVSLEE 164
           LE  +PC  C  CR G  ++CP  ++   P VD  G  A +V  P + C+ +P  +   +
Sbjct:  88 LESHLPCGTCYTCRRGWAHVCPKTRY---PGVDFDGGFASFVVVPESVCWPVPCGIPPLQ 144

Query: 165 GAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLA 224
             M EP  +AVHA+       G  VLV G GPIGL+N   AKA GAS ++ TDI   RL 
Sbjct: 145 ATMMEPFGLAVHASLEGSGVSGLNVLVSGCGPIGLMNIAAAKALGASKVIATDIHPLRLT 204

Query: 225 FAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVVRPGGR 284
            A    GAD  IN     E      V+  L     D+A+D +G  + ++  +  +  GG 
Sbjct: 205 -AAAKMGADECINA---TEESVYKTVRSLLGERGVDVAIDYSGQAAALKELIQSITHGGE 260

Query: 285 ICLVGMGSSAMHVPLVDASSREIDIFGVF--RYSNTYPTCIALLASGRVNVKPLITHRFM 342
           + L+G+ S  + + L +   + + + G+   R   T+    +LL +GRV++  L++HR  
Sbjct: 261 LRLMGVPSHDILLNLEEWLFKGLIVRGLHGRRLYETWERSTSLLVTGRVDLSSLVSHR-- 318

Query: 343 GLEESSLEAAFETA 356
            L  S+ E AFE A
Sbjct: 319 -LPLSAAEDAFEMA 331

ref|ZP_00214737.1| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Burkholderia cepacia R18194]
(353 aa)

Score: 154 bits (388), Expect: 5.40601e-36
Length: 326, Idn/Pos/Gap = 111/160/21 (34%/49%/6%)

Query:  30 PRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVH-------YWWHGSCGPFRLHDPMIIG  82
           P + RV   + P P   E+ +++   GIC SD         +W  G   P+ +  P+I G
Sbjct:   9 PEDYRVEQVAKPRPGANELVIRIAACGICASDCKCYTGAKMFW--GGPSPW-VKAPVIPG  65

Query:  83 HESAGVVEALGAGVTS---LQVGDRVALEPGVPCLQCQRCREGRYNLCP--NIKFFATPP 137
           HE  G VEALG G      + VGDRV  E  VPC +C+ C+ G+Y +C   NI  F    
Sbjct:  66 HEFFGYVEALGDGAAEHFGVAVGDRVIAEQIVPCGKCRYCKSGQYWMCEVHNIFGFQREV 125

Query: 138 VDGSLARYV-CHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGP 196
            DG +A Y+   P A  +R+P  VSLE+ A+ EPLS A+H   R    +  +V++ GAGP
Sbjct: 126 ADGGMAEYMRIPPTAIVHRIPLGVSLEDAAIIEPLSCAIHTVNRGDVQLDDVVVIAGAGP 185

Query: 197 IGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDG 256
           +GL+   VA       +VV D+ D RL  A  + GAD  IN +     DA  +V+   DG
Sbjct: 186 LGLMMTQVAHLKTPKKLVVIDLIDERLELAREY-GADVTINPK---RDDAREIVRSLTDG 241

Query: 257 AQADIALDCAGLESTMRLAMHVVRPGGRICLVGM-GSSAMHVPLVDASSREIDIFGVFRY 315
              D+ ++  G    +   + ++R  GR     + G  A     +    +E+D+ G    
Sbjct: 242 YGCDVYIETTGAPVGVSQGLDLIRKLGRFVEFSVFGEDATVDWSIIGDRKELDVRGAHLG 301

Query: 316 SNTYPTCIALLASGRVNVKPLITHRF 341
              YP  I LLA G V  K ++TH F
Sbjct: 302 PYCYPIAIDLLARGLVTSKGIVTHDF 327

gb|AAL78068.1| arabitol-phosphate dehydrogenase [Enterococcus avium]
(352 aa)

Score: 154 bits (388), Expect: 5.40601e-36
Length: 311, Idn/Pos/Gap = 109/166/19 (35%/53%/6%)

Query:  39 SVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTS  98
           SVP     +V +++   GICGSD+H +      P     P+++GHE +G V  +GA V  
Sbjct:  24 SVPEATDDKVLIKVAYTGICGSDIHTFKGEYKNP---TTPVVLGHEFSGQVVEVGANVPK  80

Query:  99 LQVGDRVALEPGV-PCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLP 157
           ++VGDRV  E     C +C  C+E +YNLCP+ K   T   +GS+A YV       + LP
Sbjct:  81 VKVGDRVTSETTFYVCGECDYCKEKQYNLCPHRKGIGTQQ-NGSMANYVLAREESIHLLP 139

Query: 158 ESVSLEEGAMCEPLSVAVHA-NRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVT 216
           + +S E  AM EPL+  VHA  +++   +   ++++G GPIGL    +AK  GA  +++T
Sbjct: 140 DHLSYEGAAMSEPLACCVHAMYQKSHLELKDTIIIMGPGPIGLYLLQIAKEIGA-FVIMT 198

Query: 217 DI--DDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRL 274
            I  D  RLA A+   GAD +++T    + D A VV +  DG   D   D +G    +  
Sbjct: 199 GITKDAHRLALAKK-LGADVIVDTM---KEDLAKVVNEITDGYGVDKVYDASGAVPAVNA 254

Query: 275 AMHVVRPGGRICLVGMGSSAMHVPLVDAS--SREIDIFGVFRYSNTY--PTCIALLASGR 330
           ++ ++R  G+   VG+ ++ M V L   S   REI+  G  R  N Y  P  I LLA G 
Sbjct: 255 SLPLIRKQGQFIQVGLFANKM-VDLDTESIIQREIEYIGS-RSQNPYDWPIAIHLLAKGA 312

Query: 331 VNVKPLITHRF 341
           +N+  +IT ++
Sbjct: 313 INIDEMITKKY 323

ref|NP_940451.1| Putative zinc-binding alcohol dehydrogenase [Corynebacterium diphtheriae NCTC 13129]
emb|CAE50665.1| Putative zinc-binding alcohol dehydrogenase [Corynebacterium diphtheriae]
(363 aa)

Score: 153 bits (387), Expect: 7.54783e-36
Length: 354, Idn/Pos/Gap = 108/177/21 (30%/50%/5%)

Query:  31 RELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSC--------GPFRLHD-PMII  81
           +++R+   S     PG  R+++   GICG+D+H +  G           P    D P+ +
Sbjct:  10 KDIRIEEISEQPLLPGTARIKVAWCGICGTDLHEFLEGPLFVPEHHHPHPVSGEDSPVTL  69

Query:  82 GHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGR-YNLCPNIKFFATPPVDG 140
           GHE +GV+  +   VT L VGD V +EP +             Y+L  ++ F       G
Sbjct:  70 GHEMSGVITEVAEDVTDLAVGDHVVVEPYLIHDDVDTSEANPFYHLSRDMNFIGLAGGGG 129

Query: 141 SLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAG-----TTIGSLVLVLGAG 195
            L+  +     W +++   + L+E A+ EPLSV  HA  RAG        G + LV GAG
Sbjct: 130 GLSENIVVKRRWIHKISPDLPLDEAALIEPLSVGYHAVERAGFASEEAAKGKVALVGGAG 189

Query: 196 PIGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALD 255
           PIGLL   V KAFGA++ V++++   R   A     AD  +N  ++D  +    + +  D
Sbjct: 190 PIGLLTASVLKAFGATV-VISELSPLRRKKALDSGAADYALNPAEVDVVEE---IAKLTD 245

Query: 256 GAQADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRY 315
           G  AD+A +C  ++  +   M  VRPG  I +V + S   +  +     +EID+ G   Y
Sbjct: 246 GKGADVAFECTSVQVVLDTLMDAVRPGAVIVVVSIWSKRSNFDIHKLVMKEIDLRGTIAY 305

Query: 316 SNTYPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLT 369
           S+ +P  I L+ SG++N+KP IT + + L++  ++  F+T       AVK++++
Sbjct: 306 SHAHPNTIKLVESGKINLKPFITGK-IALQD-IVDKGFDTLINHNETAVKILVS 357

ref|NP_344540.1| Sorbitol dehydrogenase [Sulfolobus solfataricus P2]
gb|AAK43330.1| Sorbitol dehydrogenase [Sulfolobus solfataricus P2]
pir||C90509 sorbitol dehydrogenase [imported] - Sulfolobus solfataricus
(345 aa)

Score: 152 bits (385), Expect: 1.26616e-35
Length: 347, Idn/Pos/Gap = 104/175/32 (29%/50%/9%)

Query:  34 RVMLRSVPAPA--PGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEA  91
           + +++ +P P    G+V ++M+  G+CG+D+       CG +    P I+GHE  G+++ 
Sbjct:  17 KAVIKELPLPKLQQGDVLVKMKACGLCGTDIE----KICGQYTASQP-ILGHEPTGIIQE  71

Query:  92 LGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAA 151
             + V  L+ GDRV     VPC +C  C++G   +CP  +     P  G  + Y   PA 
Sbjct:  72 --STVDWLKPGDRVFAHHHVPCYECYYCKKGSPTMCPYYRKTNLDP--GGFSEYFRVPA- 126

Query: 152 W------CYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVA 205
           W        +LP++VS EEGA  EPL+  + A +R     G  V ++G GP+GLL+ M+A
Sbjct: 127 WNVARGGVLKLPDNVSFEEGAFIEPLATVIRAQKRVAIDNGDTVFIVGIGPMGLLHAMMA 186

Query: 206 KAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDC 265
           K   A +I+ +D+ D R  F     G +  +N + ++  D    V++  DG  AD+ +  
Sbjct: 187 KVNKAGVIIASDVSDFRTEFG-YKVGINYSLNAKKVNVVDE---VKRLTDGRGADVTIIA 242

Query: 266 AGLESTMRLAMHVVRPGGRICLVGM--GSSAMHVPLVDASSREIDIF-GVFRYSNTYPTC 322
           +G  S +   ++  R GGR+ L G+    + ++  + D  + EI I              
Sbjct: 243 SGSPSAIVSGLNATRKGGRVLLFGVPYKGTILNYDISDLLNNEISIIPSNAAVEEDTKEA 302

Query: 323 IALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANG-AVKVML 368
           +A++A+ +++V  LITHRF      SL+   E  R    G A+KV++
Sbjct: 303 LAIIANKKIDVTKLITHRF------SLDEFNEAVRIGKEGNAIKVII 343

emb|CAE11232.1| YjmD protein [Bacillus amyloliquefaciens]
(327 aa)

Score: 152 bits (383), Expect: 1.75312e-35
Length: 295, Idn/Pos/Gap = 98/150/9 (33%/50%/3%)

Query:  47 EVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGDRVA 106
           +V ++++ VGICGSD+H + HG+     L  P +IGHE  G V   G+ V   + GDRV 
Sbjct:  15 DVLVKVKRVGICGSDLHIY-HGTNPLASL--PRVIGHEVTGEVANTGSHVRRFKPGDRVV  71

Query: 107 LEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPESVSLEEGA 166
           +EP   C  C  CR+GR N+C  +  F     DG +  Y+  P    + +   +  EE  
Sbjct:  72 VEPISYCGTCYACRKGRPNVCKALSVFGVHE-DGGMREYIVVPEKQLHAVSPDLPWEEAV 130

Query: 167 MCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFA 226
           M EP ++   A  R        VL+ GAGPIG+    +AK  GAS++ +TD++D RLAFA
Sbjct: 131 MAEPYTIGAQAVWRGRVEKEDTVLIHGAGPIGICILKMAKFKGASVM-ITDLNDERLAFA 189

Query: 227 ETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVVRPGGRIC 286
           E + GAD  +N +   + D  L V +      A++ +D   L ST   ++  V P G + 
Sbjct: 190 EKN-GADVTVNAQ---KEDPVLRVNEWTKKEGANVVIDAVCLPSTFETSIDAVSPAGHVV 245

Query: 287 LVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASGRVNVKPLITHRF 341
           ++G     + +  +  + +E+ I G    +N +P    LL  G +    LITH F
Sbjct: 246 VLGFDERTVGISQLPITKKEVTITGSRLQTNQFPYITDLLNKGLLTHGGLITHTF 300

ref|NP_469849.1| hypothetical protein lin0506 [Listeria innocua Clip11262]
emb|CAC95738.1| lin0506 [Listeria innocua]
pir||AB1496 polyol (sorbitol) dehydrogenase homolog lin0506 [imported] - Listeria innocua (strain Clip11262)
(348 aa)

Score: 152 bits (383), Expect: 1.79755e-35
Length: 329, Idn/Pos/Gap = 105/166/35 (31%/50%/10%)

Query:  31 RELRVMLRSVPA-PAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVV  89
           R+LR     +P    P +V L+++ VGICGSD+  +     GP+     M+ GHE +G V
Sbjct:  10 RDLRYEDADMPTIEQPDDVILKVKTVGICGSDISRY--SKLGPYV--PGMVWGHEFSGEV  65

Query:  90 EALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFF-ATPPVDGSLARYVCH 148
             +G+ VT +++GDR A  P + C +C+ C++G +  C  +    A  P  G+ A Y+  
Sbjct:  66 IEVGSAVTDIEIGDRAAGCPALYCGECEYCKKGEFARCRKLTVIGARHP--GAYAEYIKL 123

Query: 149 PAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAF 208
           PA    ++P+ +  E  A+ EP +V VH         G  V+V+G+G IGLL    AK F
Sbjct: 124 PAENVVKIPDELDYEAAALVEPSAVVVHGFYHTKLQAGDDVVVVGSGNIGLLAIQWAKVF 183

Query: 209 GASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGL 268
           GA  ++  D+DD++LA A+   GAD VIN+    + D   VV    DG  AD+ ++ AG 
Sbjct: 184 GARRVIAIDVDDKKLALAK-EVGADVVINSL---KEDPLEVVAAHTDGLNADLVVEAAGS 239

Query: 269 ESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDAS----------SREIDIFGVFR-YSN 317
             T        + GG +  +G       +P  D +            E+ ++G +   S 
Sbjct: 240 PITSAQVFAYAKKGGGVVFLG-------IPYADVTIERFYFEKIVRSELTVWGSWNAISA 292

Query: 318 TYP-----TCIALLASGRVNVKPLITHRF 341
            +P     T I  LA+ ++N++P+ITHR 
Sbjct: 293 PFPGKEWQTTIHFLANKQINIEPMITHRL 321

ref|ZP_00233077.1| alcohol dehydrogenase, zinc-dependent [Listeria monocytogenes str. 1/2a F6854]
ref|ZP_00230077.1| alcohol dehydrogenase, zinc-dependent [Listeria monocytogenes str. 4b H7858]
gb|EAL10007.1| alcohol dehydrogenase, zinc-dependent [Listeria monocytogenes str. 4b H7858]
gb|EAL07002.1| alcohol dehydrogenase, zinc-dependent [Listeria monocytogenes str. 1/2a F6854]
(350 aa)

Score: 152 bits (383), Expect: 1.88983e-35
Length: 331, Idn/Pos/Gap = 107/169/22 (32%/51%/6%)

Query:  47 EVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGDRVA 106
           +VR++++ VGICGSD+H        P     P ++GHE AGVV  +G+ VT++ +GDRVA
Sbjct:  26 QVRVEVKAVGICGSDIHKMQTRWKYPL----PAVMGHEFAGVVTEIGSEVTNVAIGDRVA  81

Query: 107 LEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPESVSLEEGA 166
             P  PC++C  C+ G + LC N +   +    G  A  V   A     + + +  EEGA
Sbjct:  82 GIPLEPCMECNYCKAGDFALCDNYRMVGS-HFHGGFAENVVMKADNVISIGD-LDFEEGA 139

Query: 167 MCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFA 226
           M EPL+V++H        +G  V+V G G IG+L        G   I+  DI D++LA A
Sbjct: 140 MIEPLAVSMHGVLGIQPRLGDTVIVFGIGTIGILVVQCLLLAGVKDIIAVDISDKKLADA 199

Query: 227 ETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVVRPGGRIC 286
               G    IN ++ D  +         +G  ADIAL+CAG + T    + V +  G++ 
Sbjct: 200 REF-GCKYTINPKNEDLKERVFAYT---NGLGADIALECAGSKITQEQCLLVTKKKGKVG 255

Query: 287 LVGMGSSAMHV---PLVDASSREIDIFGVFR-YSNTYP-----TCIALLASGRVNVKPLI 337
            +G+  + + +      +   RE+ + G +  YS  +P     T I  +  GR+ +KPLI
Sbjct: 256 FLGIAYADVLLHEEAFENIFRRELTLKGFWNSYSAPFPGEEWRTSIEFVKQGRIKLKPLI 315

Query: 338 THRFMGLEESSLEAAFETARTAANGAVKVML 368
           +HR+  LEE+  + AF+   +  +   KVM+
Sbjct: 316 SHRYK-LEET--KEAFDMILSREHDYNKVMI 343

ref|YP_075702.1| threonine 3-dehydrogenase [Symbiobacterium thermophilum IAM 14863]
dbj|BAD40858.1| threonine 3-dehydrogenase [Symbiobacterium thermophilum IAM 14863]
(351 aa)

Score: 152 bits (383), Expect: 1.92163e-35
Length: 334, Idn/Pos/Gap = 113/171/15 (33%/51%/4%)

Query:  37 LRSVPAP--APGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGA  94
           L+ VP P   P +V +++R   ICG+D H +        R+  P+ IGHE AG V A+G 
Sbjct:  19 LQEVPIPTIGPRDVLVKVRAASICGTDYHIYTWDPWSAGRVKPPLTIGHELAGEVVAVGR  78

Query:  95 GVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCY 154
            VT+ +VGD V+ E  + C +C RC  G Y+LC N K       DG+ A YV  P    +
Sbjct:  79 EVTACKVGDYVSAETHIVCNRCPRCHMGEYHLCENTKILGV-DTDGAFAEYVAVPEQNIW 137

Query: 155 RLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIV 214
              + +  E  ++ EPL  AVH       T  S VL+ G GPIG+++  VAK  GA I++
Sbjct: 138 VNDKDIPFELQSIQEPLGNAVHTALNGDLTARS-VLITGCGPIGIMSVPVAKMAGAEIVM 196

Query: 215 VTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRL 274
             DI++ RL  A    GAD +IN     + D   VV+    G  AD+ L+ +G  + +R 
Sbjct: 197 AMDINEYRLQLA-GQLGADVLINP---TKQDPVEVVRSYTRGYGADVVLEMSGNPTAIRQ 252

Query: 275 AMHVVRPGGRICLVGMGSSAMHVPL-VDASSREIDIFGVF--RYSNTYPTCIALLASGRV 331
            +   R G RI L+G+    + + L  D   R + + G+   R   T+    +L  +G  
Sbjct: 253 GLKAARNGARISLLGLPGRPLELDLAADVIMRGLVLQGITGRRMWQTWYQVRSLYRAGLA 312

Query: 332 N-VKPLITHRFMGLEESSLEAAFETARTAANGAV 364
             ++PL+THR M LE+  ++AA E   +  +G +
Sbjct: 313 ERLRPLVTHR-MPLEQ--IDAAMELMGSGQSGKI 343

dbj|BAB07668.1| L-iditol 2-dehydrogenase [Bacillus halodurans C-125]
ref|NP_244817.1| L-iditol 2-dehydrogenase [Bacillus halodurans C-125]
pir||E84143 L-iditol 2-dehydrogenase BH3949 [imported] - Bacillus halodurans (strain C-125)
(348 aa)

Score: 152 bits (383), Expect: 1.98685e-35
Length: 336, Idn/Pos/Gap = 105/172/18 (31%/51%/5%)

Query:  31 RELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSC-----GPFRLHD---PMIIG  82
           +++RV   + PA   G+V+++++  GICGSD+H +  G        P  L +   P+++G
Sbjct:  10 KDVRVDDIAEPATLKGKVKIKVKWCGICGSDLHEYAAGPIFIPQNSPHSLTEEKAPIVMG  69

Query:  83 HESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSL 142
           HE +G V  +G GVT  + GDRV +EP   C  C  C++G+YNLC  + F       G  
Sbjct:  70 HEFSGQVVEVGDGVTKCEEGDRVVVEPIFACGTCTACKQGKYNLCEQLGFLGLAGGGGGF 129

Query: 143 ARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNC 202
           + YV       +++P++VS E+GA+ EP +VA++A R++   +G   +V G GPIGLL  
Sbjct: 130 SEYVTVDEHMVHKIPDTVSFEQGALVEPAAVALYAVRQSQFNVGDQAVVFGTGPIGLLVI 189

Query: 203 MVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIA 262
              KA GAS I   ++   R   AE   GA A+    +  E +    +Q+  DG  AD++
Sbjct: 190 EALKASGASKIYAVELSTERRQRAE-QLGAIAL----NPAEVNVVEEIQRLTDGG-ADVS 243

Query: 263 LDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTC 322
            +  G+   +  A+   +  G+  +V +              RE +I G+  Y + +P  
Sbjct: 244 FEVTGVPIVLTQAIESTKLNGQTMIVSIFEKEASFQPNLVVMRERNIAGIIGYRDIFPAV 303

Query: 323 IALLASGRVNVKPLITHRFMGLE---ESSLEAAFET 355
           I+L+  G  + + L+T R +GL    E   EA  +T
Sbjct: 304 ISLMNQGYFSAETLVTKR-IGLHDIVEQGFEALMKT 338

gb|AAT02414.1| xylitol-phosphate dehydrogenase [Lactobacillus rhamnosus]
(349 aa)

Score: 152 bits (383), Expect: 2.21448e-35
Length: 340, Idn/Pos/Gap = 106/167/26 (31%/49%/7%)

Query:  40 VPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSL  99
           +P+P   EV +++   G CGSD H    G    ++   P ++GHE +G+V  LG  V+++
Sbjct:  19 IPSPKKDEVVVKVMAAGTCGSDSHKMISG----WKYGYPAVMGHEFSGIVTQLGENVSNV  74

Query: 100 QVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPES 159
            VG  VA+ P +PC +C  C+ G + +C N          G   +YV  PA     + + 
Sbjct:  75 SVGQHVAVAPFIPCFKCHYCQIGLFQMCENYSMLGQQKF-GGFEQYVSVPARNVLDIGK- 132

Query: 160 VSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDID 219
           +S EEGA+ EP++VA HA       +G  V V G G +G L   +  + GA+ ++  DID
Sbjct: 133 MSFEEGALIEPMAVAAHAVMGIKPELGDTVAVFGLGTVGDLVVRLLISSGATNVIGIDID 192

Query: 220 DRRLAFAETHAGADAVINT--RDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMH 277
           D++L       G   VIN+    L+E      + +  DG   DI+++CAG + T    + 
Sbjct: 193 DQKLE-KGLDEGCTHVINSAKESLEEK-----IMEYTDGLGVDISMECAGSKITEEQTLL 246

Query: 278 VVRPGGRICLVGMGSS--AMHVPLVDASSR-EIDIFGVFR-YSNTYP-----TCIALLAS 328
           V +  G++  VG+  S   +H    +   R E+ + G +  YS  +P       I L+  
Sbjct: 247 VTKRRGKVGFVGIAYSDVLLHQKAFENIFRHELTVTGFWNSYSAPFPGREWTNSIQLVNR 306

Query: 329 GRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVML 368
           GR+ +K LITHRF   E   ++ AF    T +    KVM 
Sbjct: 307 GRIKIKDLITHRF---ELEDMQKAFNMITTRSESFNKVMF 343

ref|YP_013140.1| alcohol dehydrogenase, zinc-dependent [Listeria monocytogenes str. 4b F2365]
ref|ZP_00230906.1| alcohol dehydrogenase, zinc-dependent [Listeria monocytogenes str. 4b H7858]
gb|EAL09260.1| alcohol dehydrogenase, zinc-dependent [Listeria monocytogenes str. 4b H7858]
gb|AAT03317.1| alcohol dehydrogenase, zinc-dependent [Listeria monocytogenes str. 4b F2365]
(348 aa)

Score: 152 bits (383), Expect: 2.23304e-35
Length: 329, Idn/Pos/Gap = 105/166/35 (31%/50%/10%)

Query:  31 RELRVMLRSVPA-PAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVV  89
           R+LR     +P    P +V L+++ VGICGSD+  +     GP+     M+ GHE +G V
Sbjct:  10 RDLRYEEADMPTIEQPDDVILKVKTVGICGSDISRY--SKLGPYV--PGMVWGHEFSGEV  65

Query:  90 EALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFF-ATPPVDGSLARYVCH 148
             +G+ VT +++GDR A  P + C +C+ C++G +  C  +    A  P  G+ A Y+  
Sbjct:  66 IEVGSEVTDIEIGDRAAGCPALYCGECEYCKKGEFARCRKLTVIGARHP--GAYAEYIKL 123

Query: 149 PAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAF 208
           PA    ++P+ +  E  A+ EP +V VH         G  V+V+G+G IGLL    AK F
Sbjct: 124 PAENVVKIPDELDYEAAALVEPSAVVVHGFYHTKLQAGDDVVVVGSGNIGLLAIQWAKVF 183

Query: 209 GASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGL 268
           GA  ++  D+DD++LA A+   GAD VIN+    + D   VV    DG  AD+ ++ AG 
Sbjct: 184 GAKRVIAIDVDDKKLALAK-EVGADVVINSL---KEDPLEVVAAHTDGLNADLVVEAAGS 239

Query: 269 ESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDAS----------SREIDIFGVFR-YSN 317
             T        + GG +  +G       +P  D +            E+ ++G +   S 
Sbjct: 240 PITSAQVFAYAKKGGGVVFLG-------IPYADVTIERFYFEKIVRSELTVWGSWNAISA 292

Query: 318 TYP-----TCIALLASGRVNVKPLITHRF 341
            +P     T I  LA+ ++N++P+ITHR 
Sbjct: 293 PFPGKEWQTTIHFLANKQINIEPMITHRL 321

ref|YP_015232.1| alcohol dehydrogenase, zinc-dependent [Listeria monocytogenes str. 4b F2365]
gb|AAT05409.1| alcohol dehydrogenase, zinc-dependent [Listeria monocytogenes str. 4b F2365]
(350 aa)

Score: 151 bits (382), Expect: 2.89221e-35
Length: 331, Idn/Pos/Gap = 107/169/22 (32%/51%/6%)

Query:  47 EVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGDRVA 106
           +VR++++ VGICGSD+H        P     P ++GHE AGVV  +G+ VT++ +GDRVA
Sbjct:  26 QVRVEVKAVGICGSDIHKMQTRWKYPL----PAVMGHEFAGVVTEIGSEVTNVAIGDRVA  81

Query: 107 LEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPESVSLEEGA 166
             P  PC++C  C+ G + LC N +   +    G  A  V   A     + + +  EEGA
Sbjct:  82 GIPLEPCMECNYCKAGDFALCDNYRMVGS-HFHGGFAENVVMKADNVISIGD-LDFEEGA 139

Query: 167 MCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFA 226
           M EPL+V++H        +G  V+V G G IG+L        G   I+  DI D++LA A
Sbjct: 140 MIEPLAVSMHGVLGIQPRLGDTVIVFGIGTIGILVVQCLLLAGVKDIIAVDISDKKLADA 199

Query: 227 ETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVVRPGGRIC 286
               G    IN ++ D  +         +G  ADIAL+CAG + T    + V +  G++ 
Sbjct: 200 REF-GCKYTINPKNEDLKERVFAYT---NGLGADIALECAGSKITQEQCLLVTKKKGKVG 255

Query: 287 LVGMGSSAMHV---PLVDASSREIDIFGVFR-YSNTYP-----TCIALLASGRVNVKPLI 337
            +G+  + + +      +   RE+ + G +  YS  +P     T I  +  GR+ +KPLI
Sbjct: 256 YLGIAYADVLLHEEAFENIFRRELTLKGFWNSYSAPFPGEEWRTSIEFVKQGRIKLKPLI 315

Query: 338 THRFMGLEESSLEAAFETARTAANGAVKVML 368
           +HR+  LEE+  + AF+   +  +   KVM+
Sbjct: 316 SHRYK-LEET--KEAFDMILSREHDYNKVMI 343

ref|NP_806859.1| galactitol-1-phosphate dehydrogenase [Salmonella enterica subsp. enterica serovar Typhi Ty2]
ref|NP_457645.1| galactitol-1-phosphate dehydrogenase [Salmonella enterica subsp. enterica serovar Typhi str. CT18]
emb|CAD07783.1| galactitol-1-phosphate dehydrogenase [Salmonella enterica subsp. enterica serovar Typhi]
gb|AAO70719.1| galactitol-1-phosphate dehydrogenase [Salmonella enterica subsp. enterica serovar Typhi Ty2]
pir||AI0898 galactitol-1-phosphate dehydrogenase [imported] - Salmonella enterica subsp. enterica serovar Typhi (strain CT18)
(347 aa)

Score: 151 bits (382), Expect: 2.91644e-35
Length: 355, Idn/Pos/Gap = 117/175/52 (32%/49%/14%)

Query:  32 ELRVMLRSVPA-PAPGEVRLQMRCVGICGSDV--------HYWWHGSCGPFRLHDPMIIG  82
           ++RV  R +P   A  +V +++   G+CGSD+        HY+            P+ +G
Sbjct:  11 DVRVEERPLPQLQAEDDVLVKVVSSGLCGSDIPRIFAQGAHYY------------PITLG  58

Query:  83 HESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSL 142
           HE +G VE+ G GVT +Q GD VA  P +PC  C +C  G ++LC   +F  +   +G  
Sbjct:  59 HEFSGYVESYGTGVTDMQPGDAVACVPLLPCFHCPQCERGYFSLCKQYQFVGSRS-EGGN 117

Query: 143 ARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNC 202
           A YV    A  +RLP  + +E+GA  EP++V +HA   A    G  V+++GAG IGLL  
Sbjct: 118 AEYVVVKRANLFRLPSDMPIEDGAFIEPITVGLHAFHLAQGCEGKNVIIVGAGTIGLLAL 177

Query: 203 MVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQAD-I 261
             A+  GA  +   DI+ ++L  A+   GA    N+R++   D    +Q AL   Q D +
Sbjct: 178 QCARELGARSVTAIDINPQKLELAKA-LGATHTCNSREMTADD----IQTALSDIQFDQL 232

Query: 262 ALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDAS-------SREIDIFGVF- 313
            L+ AG   T+ LA+ +  P  ++ LVG     +H  L   +        +E+ + G + 
Sbjct: 233 VLETAGTPQTVSLAIDITGPRAQLALVG----TLHHDLTLTTRTFGLILRKELTLLGSWM 288

Query: 314 RYSNTYP-----TCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGA 363
            YS  +P     T   LLA  R+ + PLI HR  G  ES     F  A  A NGA
Sbjct: 289 NYSAPWPGEEWETAARLLAEKRLQLTPLIAHR--GDAES-----FAEAVKALNGA 336

ref|NP_472142.1| hypothetical protein lin2813 [Listeria innocua Clip11262]
emb|CAC98039.1| lin2813 [Listeria innocua]
pir||AG1783 sorbitol dehydrogenase homolog lin2813 [imported] - Listeria innocua (strain Clip11262)
(350 aa)

Score: 151 bits (381), Expect: 3.09185e-35
Length: 331, Idn/Pos/Gap = 107/169/22 (32%/51%/6%)

Query:  47 EVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGDRVA 106
           +VR++++ VGICGSD+H        P     P ++GHE AGVV  +G+ VT++ +GDRVA
Sbjct:  26 QVRVEVKAVGICGSDIHKMQTRWKYPL----PAVMGHEFAGVVTEIGSEVTNVAIGDRVA  81

Query: 107 LEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPESVSLEEGA 166
             P  PC++C  C+ G + LC N +   +    G  A  V   A     + + +  EEGA
Sbjct:  82 GIPLEPCMECNYCKAGDFALCDNYRMVGS-HFHGGFAENVVMKADNVISIGD-LDFEEGA 139

Query: 167 MCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFA 226
           M EPL+V++H        +G  V+V G G IG+L        G   I+  DI D++LA A
Sbjct: 140 MIEPLAVSMHGVLGIEPRLGDTVIVFGIGTIGILVVQCLLLAGVKDIIAVDISDKKLADA 199

Query: 227 ETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVVRPGGRIC 286
               G    IN ++ D  +         +G  ADIAL+CAG + T    + V +  G++ 
Sbjct: 200 REF-GCKYTINPKNEDLKERVFAYT---NGLGADIALECAGSKITQEQCLLVTKKKGKVG 255

Query: 287 LVGMGSSAMHV---PLVDASSREIDIFGVFR-YSNTYP-----TCIALLASGRVNVKPLI 337
            +G+  + + +      +   RE+ + G +  YS  +P     T I  +  GR+ +KPLI
Sbjct: 256 YLGIAYADVLLHEEAFENIFRRELTLKGFWNSYSAPFPGEEWRTSIEFVKQGRIKLKPLI 315

Query: 338 THRFMGLEESSLEAAFETARTAANGAVKVML 368
           +HR+  LEE+  + AF+   +  +   KVM+
Sbjct: 316 SHRYK-LEET--KEAFDMILSREHDYNKVMI 343

ref|YP_152271.1| galactitol-1-phosphate dehydrogenase [Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150]
gb|AAV78959.1| galactitol-1-phosphate dehydrogenase [Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150]
ref|YP_218189.1| galactitol-1-phosphate dehydrogenase [Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67]
gb|AAX67108.1| galactitol-1-phosphate dehydrogenase [Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67]
gb|AAL22133.1| galactitol-1-phosphate dehydrogenase [Salmonella typhimurium LT2]
ref|NP_462174.1| galactitol-1-phosphate dehydrogenase [Salmonella typhimurium LT2]
(347 aa)

Score: 151 bits (381), Expect: 3.22357e-35
Length: 355, Idn/Pos/Gap = 117/175/52 (32%/49%/14%)

Query:  32 ELRVMLRSVPA-PAPGEVRLQMRCVGICGSDV--------HYWWHGSCGPFRLHDPMIIG  82
           ++RV  R +P   A  +V +++   G+CGSD+        HY+            P+ +G
Sbjct:  11 DVRVEERPLPQLQAEDDVLVKVVSSGLCGSDIPRIFAQGAHYY------------PITLG  58

Query:  83 HESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSL 142
           HE +G VE+ G GVT +Q GD VA  P +PC  C +C  G ++LC   +F  +   +G  
Sbjct:  59 HEFSGYVESYGTGVTDMQPGDAVACVPLLPCFHCPQCERGYFSLCKQYQFVGSRS-EGGN 117

Query: 143 ARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNC 202
           A YV    A  +RLP  + +E+GA  EP++V +HA   A    G  V+++GAG IGLL  
Sbjct: 118 AEYVVVKRANLFRLPSDMPIEDGAFIEPITVGLHAFHLAQGCEGKNVIIVGAGTIGLLAL 177

Query: 203 MVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQAD-I 261
             A+  GA  +   DI+ ++L  A+   GA    N+R++   D    +Q AL   Q D +
Sbjct: 178 QCARELGARSVTAIDINPQKLELAKA-LGATHTCNSREMTADD----IQTALSDIQFDQL 232

Query: 262 ALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDAS-------SREIDIFGVF- 313
            L+ AG   T+ LA+ +  P  ++ LVG     +H  L   +        +E+ + G + 
Sbjct: 233 VLETAGTPQTVSLAIDIAGPRAQLALVG----TLHHDLTLTTRTFGLILRKELTLLGSWM 288

Query: 314 RYSNTYP-----TCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGA 363
            YS  +P     T   LLA  R+ + PLI HR  G  ES     F  A  A NGA
Sbjct: 289 NYSAPWPGEEWETAARLLAEKRLQLTPLIAHR--GDAES-----FAEAVKALNGA 336

ref|ZP_00232347.1| alcohol dehydrogenase, zinc-dependent [Listeria monocytogenes str. 1/2a F6854]
gb|EAL07790.1| alcohol dehydrogenase, zinc-dependent [Listeria monocytogenes str. 1/2a F6854]
(348 aa)

Score: 151 bits (381), Expect: 3.33297e-35
Length: 329, Idn/Pos/Gap = 105/166/35 (31%/50%/10%)

Query:  31 RELRVMLRSVPA-PAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVV  89
           R+LR     +P    P +V L+++ VGICGSD+  +     GP+     M+ GHE +G V
Sbjct:  10 RDLRYEEADMPTIEEPDDVILKVKTVGICGSDISRY--SKLGPYV--PGMVWGHEFSGEV  65

Query:  90 EALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFF-ATPPVDGSLARYVCH 148
             +G+ VT +++GDR A  P + C +C+ C++G +  C  +    A  P  G+ A Y+  
Sbjct:  66 IEVGSEVTDIEIGDRAAGCPALYCGECEYCKKGEFARCRKLTVIGARHP--GAYAEYIKL 123

Query: 149 PAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAF 208
           PA    ++P+ +  E  A+ EP +V VH         G  V+V+G+G IGLL    AK F
Sbjct: 124 PAENVVKIPDELDYEAAALVEPSAVVVHGFYHTKLQAGDDVVVVGSGNIGLLAIQWAKVF 183

Query: 209 GASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGL 268
           GA  ++  D+DD++LA A+   GAD VIN+    + D   VV    DG  AD+ ++ AG 
Sbjct: 184 GARRVIAIDVDDKKLALAK-EVGADVVINSL---KEDPLEVVAAHTDGLNADLVVEAAGS 239

Query: 269 ESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDAS----------SREIDIFGVFR-YSN 317
             T        + GG +  +G       +P  D +            E+ ++G +   S 
Sbjct: 240 PITSAQVFAYAKKGGGVVFLG-------IPYADVTIERFYFEKIVRSELTVWGSWNAISA 292

Query: 318 TYP-----TCIALLASGRVNVKPLITHRF 341
            +P     T I  LA+ ++N++P+ITHR 
Sbjct: 293 PFPGKEWQTTIHFLANKQINIEPMITHRL 321

gb|AAM09029.1| mannitol dehydrogenase [Leuconostoc mesenteroides]
(338 aa)

Score: 151 bits (381), Expect: 3.47496e-35
Length: 318, Idn/Pos/Gap = 95/158/14 (29%/49%/4%)

Query:  26 VLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHES  85
           VL   ++L V     P   P EV +     GICG+D H  + G  G      P+++GHE+
Sbjct:   5 VLTGTKKLEVKDIDRPKVLPNEVLIHTAFAGICGTD-HALYAGLPGSADAVPPIVLGHEN  63

Query:  86 AGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARY 145
           +GVV  +G+ VT+++VGDRV ++P + C QC+ CR  R  LC N+        DG    +
Sbjct:  64 SGVVAEIGSAVTNVKVGDRVTVDPNIYCGQCKYCRTARPELCENLSAVGVTR-DGGFEEF 122

Query: 146 VCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVA 205
              PA+  Y +P++VSL+  A+ EP+S AVH  +    T     LV+G G +G L   + 
Sbjct: 123 FTAPASVVYPIPDNVSLKSAAVVEPISCAVHGIQLLKVTPYQKALVIGDGFMGELFVQIL 182

Query: 206 KAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDC 265
           +A+G   + +  I D +LA  +   G     NT   D+          +   + D+ ++ 
Sbjct: 183 QAYGIHQVDLAGIVDEKLAMNKEKFGVKNTYNTMKGDK----------IPEGEYDVIIEA 232

Query: 266 AGLESTMRLAMHVVRPGGRICLVGMG--SSAMHVPLVDASSREIDIFGVFRYSNTYPTCI 323
            GL  T   A+     G ++ + G+G   +   +   +   +++ I G F   N +   +
Sbjct: 233 VGLPQTQEAAIEASARGAQVLMFGVGGPDAKFQMNTYEVFQKQLTIQGSFINPNAFEDSL 292

Query: 324 ALLASGRVNVKPLITHRF 341
           ALL+SG++NV+ L++H  
Sbjct: 293 ALLSSGKLNVEALMSHEL 310

ref|NP_542889.1| benzyl alcohol dehydrogenase [Pseudomonas putida]
emb|CAC86829.1| xylW [Pseudomonas putida]
dbj|BAA09660.1| benzyl alcohol dehydrogenase II [Pseudomonas putida]
(348 aa)

Score: 151 bits (381), Expect: 3.80899e-35
Length: 314, Idn/Pos/Gap = 106/164/15 (33%/52%/4%)

Query:  47 EVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGDRVA 106
           +V +++   GICG+D+  +  G     R+  P I+GHE +GV+E +G+ V  L+ G RV+
Sbjct:  29 DVLVKVEAAGICGTDLLIYKWGEFAK-RMKLPTILGHEVSGVIEQVGSDVKGLRPGMRVS  87

Query: 107 LEPGVPCLQCQRCREGRYNLCPNIKFFATPPVD--GSLARYVCHPAAWCYRLPESVSLEE 164
           LE  +PC  C  CR G  ++CP  ++   P VD  G  A +V  P + C+ +P  +   +
Sbjct:  88 LESHLPCGTCYTCRRGWAHVCPKTRY---PGVDFDGGFASFVVVPESVCWPVPCGIPPLQ 144

Query: 165 GAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLA 224
            AM EP  +AVHA+       G  VLV G GPIGL+N   AKA GAS ++  DI   RL 
Sbjct: 145 AAMMEPFGLAVHASLEGSGVSGLNVLVSGCGPIGLMNIAAAKALGASKVIAPDIHPLRLT 204

Query: 225 FAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVVRPGGR 284
            A    GAD  IN     E      V+  L     D+A+D +G  + ++  +  +  GG 
Sbjct: 205 -AAAKMGADECINA---TEESVYKTVRSLLGERGVDVAIDYSGQAAALKELIQSITHGGE 260

Query: 285 ICLVGMGSSAMHVPLVDASSREIDIFGVF--RYSNTYPTCIALLASGRVNVKPLITHRFM 342
           + L+G+ S  + + L +   + + + G+   R    +    +LL +GRV++  L++HR  
Sbjct: 261 LRLMGVPSHDILLNLEEWLFKGLIVRGLHGRRLYERWERSTSLLVTGRVDLSSLVSHR-- 318

Query: 343 GLEESSLEAAFETA 356
            L  S+ E AFE A
Sbjct: 319 -LPLSAAEDAFEMA 331

ref|NP_466186.1| hypothetical protein lmo2664 [Listeria monocytogenes EGD-e]
emb|CAD00877.1| lmo2664 [Listeria monocytogenes]
pir||AG1407 sorbitol dehydrogenase homolog lmo2664 [imported] - Listeria monocytogenes (strain EGD-e)
(350 aa)

Score: 150 bits (380), Expect: 3.97125e-35
Length: 331, Idn/Pos/Gap = 106/169/22 (32%/51%/6%)

Query:  47 EVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGDRVA 106
           +VR++++ VGICGSD+H        P     P ++GHE AGV+  +G+ VT++ +GDRVA
Sbjct:  26 QVRVEVKAVGICGSDIHKMQTRWKYPL----PAVMGHEFAGVITEIGSEVTNVAMGDRVA  81

Query: 107 LEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPESVSLEEGA 166
             P  PC++C  C+ G + LC N +   +    G  A  V   A     + + +  EEGA
Sbjct:  82 GIPLEPCMECNYCKAGDFALCDNYRMVGS-HFHGGFAENVVMKADNVISIGD-LDFEEGA 139

Query: 167 MCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFA 226
           M EPL+V++H        +G  V+V G G IG+L        G   I+  DI D++LA A
Sbjct: 140 MIEPLAVSMHGVLGIQPRLGDTVIVFGIGTIGILVVQCLLLAGVKDIIAVDISDKKLADA 199

Query: 227 ETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVVRPGGRIC 286
               G    IN ++ D  +         +G  ADIAL+CAG + T    + V +  G++ 
Sbjct: 200 REF-GCKYTINPKNEDLKERVFAYT---NGLGADIALECAGSKITQEQCLLVTKKKGKVG 255

Query: 287 LVGMGSSAMHV---PLVDASSREIDIFGVFR-YSNTYP-----TCIALLASGRVNVKPLI 337
            +G+  + + +      +   RE+ + G +  YS  +P     T I  +  GR+ +KPLI
Sbjct: 256 FLGIAYADVLLHEEAFENIFRRELTLKGFWNSYSAPFPGEEWRTSIEFVKQGRIKLKPLI 315

Query: 338 THRFMGLEESSLEAAFETARTAANGAVKVML 368
           +HR+  LEE+  + AF+   +  +   KVM+
Sbjct: 316 SHRYK-LEET--KEAFDMILSREHDYNKVMI 343

ref|NP_464034.1| hypothetical protein lmo0506 [Listeria monocytogenes EGD-e]
emb|CAC98585.1| lmo0506 [Listeria monocytogenes]
pir||AC1138 polyol (sorbitol) dehydrogenase homolog lmo0506 [imported] - Listeria monocytogenes (strain EGD-e)
(348 aa)

Score: 150 bits (380), Expect: 4.69246e-35
Length: 329, Idn/Pos/Gap = 105/165/35 (31%/50%/10%)

Query:  31 RELRVMLRSVPA-PAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVV  89
           R+LR     +P    P +V L+++ VGICGSD+  +     GP+     M+ GHE +G V
Sbjct:  10 RDLRYEEADMPTIEEPDDVILKVKTVGICGSDISRY--SKLGPYV--PGMVWGHEFSGEV  65

Query:  90 EALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFF-ATPPVDGSLARYVCH 148
             +G+ VT +++GDR A  P + C +C+ C++G +  C  +    A  P  G+ A Y+  
Sbjct:  66 IEVGSEVTDIEIGDRAAGCPALYCGECEYCKKGEFARCRKLTVIGARHP--GAYAEYIKL 123

Query: 149 PAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAF 208
           PA    ++P  +  E  A+ EP +V VH         G  V+V+G+G IGLL    AK F
Sbjct: 124 PAENVVKIPNELDYEAAALVEPSAVVVHGFYHTKLQAGDDVVVVGSGNIGLLAIQWAKVF 183

Query: 209 GASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGL 268
           GA  ++  D+DD++LA A+   GAD VIN+    + D   VV    DG  AD+ ++ AG 
Sbjct: 184 GARRVIAIDVDDKKLALAK-EVGADVVINSL---KEDPLEVVAAHTDGLNADLVVEAAGS 239

Query: 269 ESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDAS----------SREIDIFGVFR-YSN 317
             T        + GG +  +G       +P  D +            E+ ++G +   S 
Sbjct: 240 PITSAQVFAYAKKGGGVVFLG-------IPYADVTIERFYFEKIVRSELTVWGSWNAISA 292

Query: 318 TYP-----TCIALLASGRVNVKPLITHRF 341
            +P     T I  LA+ ++N++P+ITHR 
Sbjct: 293 PFPGKEWQTTIHFLANKQINIEPMITHRL 321

ref|XP_396440.1| similar to Xylitol dehydrogenase [Apis mellifera]
(304 aa)

Score: 150 bits (378), Expect: 7.24153e-35
Length: 247, Idn/Pos/Gap = 88/137/11 (35%/55%/4%)

Query:  44 APGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGD 103
           +P ++ +++   G+CGSD+   +H     +    P+ +GHE +G V  +G  VT   +GD
Sbjct:  24 SPDQILVKVAYCGLCGSDIPRIFHHGAHFY----PITLGHEFSGTVIEIGDDVTEFDIGD  79

Query: 104 RVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPESVSLE 163
            ++  P +PC +C  C++  Y+LC N  F  +  + G  A Y+       ++LP+ VS  
Sbjct:  80 LISCVPLLPCFKCDECQKHYYSLCKNYTFVGSR-ITGGFAEYIVLNKKNAFKLPKQVSAL 138

Query: 164 EGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRL 223
           EGA  EP++V +HA   AG      V+++G G IGLL  + AKA GAS I V DI+D RL
Sbjct: 139 EGAFFEPMTVGMHALLLAGGCQNKHVVIVGGGTIGLLAMLCAKAMGASSITVLDINDERL 198

Query: 224 AFAETHAGADAVINTRDLDEHDAALVVQQALDGAQAD-IALDCAGLESTMRLAMHVVRPG 282
             A+   GADA  N+++L   +    + QAL   + D I L+ AG   T+RLA+ +  P 
Sbjct: 199 NLAK-RLGADATYNSKNLSSDE----IYQALSYNRFDQIVLETAGSPITVRLAIEIAGPR 253

Query: 283 GRICLVG 289
            ++ LVG
Sbjct: 254 SKVGLVG 260

ref|ZP_00132353.2| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Haemophilus somnus 2336]
ref|ZP_00122447.1| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Haemophilus somnus 129PT]
(347 aa)

Score: 150 bits (378), Expect: 7.42508e-35
Length: 312, Idn/Pos/Gap = 97/162/23 (31%/51%/7%)

Query:  40 VPAPA---PGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGV  96
           +P P    P +V +++   G+CGSD+   +H     +    P+++GHE +  VE +G+ V
Sbjct:  17 IPKPLVEDPDDVLVKVHYSGLCGSDIPRIFHHGTHFY----PIVLGHEFSATVEEVGSDV  72

Query:  97 TSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRL 156
           T L  GD V+  P  PC +C  C  G Y+LC N  F  +    G+ + Y+C   +   +L
Sbjct:  73 TELDKGDLVSCAPLQPCFKCDECNRGFYSLCKNYNFIGSRRF-GANSEYLCVKKSNLVKL 131

Query: 157 PESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVT 216
           P+     + +  EP++V +HA   AG   G  V+++GAG IGLL     KA GA+ + V 
Sbjct: 132 PQGSDTLQASFIEPITVGLHAIHLAGGCKGKNVVIVGAGTIGLLAAQSTKALGANSVSVI 191

Query: 217 DIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQAD-IALDCAGLESTMRLA 275
           DI+  +L  A+T  GAD V N+ DL   +    +   LDG + D + L+ AG+  T+ L+
Sbjct: 192 DINQEKLVLAKT-LGADYVFNSMDLKADE----ILACLDGNRFDQLILETAGVPKTVELS 246

Query: 276 MHVVRPGGRICLVGMGSSAMHVPLVDAS---SREIDIFGVF-RYSNTYP-----TCIALL 326
           + +  P  ++ LVG     +++   +      +E+ IFG +  YS  +P       + L+
Sbjct: 247 IQIAGPRAQVVLVGTLHHDLNLDQKEFGLILRKELIIFGSWMNYSKPWPGVEWREAVNLI 306

Query: 327 ASGRVNVKPLIT 338
           A  ++  +PLI+
Sbjct: 307 AENKICFEPLIS 318

ref|YP_045733.1| putative (R,R)-butanediol dehydrogenase [Acinetobacter sp. ADP1]
emb|CAG67911.1| putative (R,R)-butanediol dehydrogenase [Acinetobacter sp. ADP1]
(371 aa)

Score: 149 bits (377), Expect: 9.45772e-35
Length: 345, Idn/Pos/Gap = 104/168/17 (30%/48%/4%)

Query:  35 VMLRSVPAP--APGEVRLQMRCVGICGSDVHYWWHGS-----CG-PFRLHD---PMIIGH  83
           + +  +P P    G V +Q+   GICG+D+H +  G      CG P  +     P+ +GH
Sbjct:  31 IRIEDIPEPEVTAGTVGIQVAWCGICGTDLHEFMEGPIFIPPCGHPHPISGESAPITMGH  90

Query:  84 ESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLA 143
           E +GVV A+G GV  +QVG  V +EP +            Y+L  N+ F       G L+
Sbjct:  91 EFSGVVYAVGEGVDDIQVGQHVVVEPYIVADDVPTGPGENYHLSKNMNFIGLGGRGGGLS 150

Query: 144 RYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCM 203
             +     W + + E++ L++ A+ EPLSV  HA  R+G   G + LV GAGPIGLL   
Sbjct: 151 EKIAVQRRWVHPISENIPLDQAALIEPLSVGHHAYVRSGAKAGDVALVGGAGPIGLLLSA 210

Query: 204 VAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIAL 263
           + KA G ++I +T++  +R   A+    AD +++   +D     + + Q      ADIA 
Sbjct: 211 ILKAKGLTVI-ITELSSKRKEKAKESGVADYILDPTQVDVIAEVMKITQ---DKGADIAF 266

Query: 264 DCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCI 323
           +C+ +   +   +   +P G I +V + S    V +     +E+DI G   Y N +   I
Sbjct: 267 ECSSVNKVLDTLVASTKPTGVIVIVSIWSHPATVNVHSVVMKELDIRGTIAYVNDHQETI 326

Query: 324 ALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVML 368
            L+  G++N+ P IT R     +  +   FET       AVK+++
Sbjct: 327 KLVEQGKINLAPFITQRIK--LDDLISQGFETLIHNNESAVKIIV 369

emb|CAD31644.1| mannitol-2-dehydrogenase [Leuconostoc pseudomesenteroides]
(338 aa)

Score: 149 bits (377), Expect: 1.01106e-34
Length: 318, Idn/Pos/Gap = 94/158/14 (29%/49%/4%)

Query:  26 VLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHES  85
           VL   ++L V     P   P EV +     GICG+D H  + G  G      P+++GHE+
Sbjct:   5 VLTGTKKLEVENIEQPEVKPNEVLIHTAFAGICGTD-HALYAGLPGSADAVPPIVLGHEN  63

Query:  86 AGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARY 145
           +GVV  +G+ VT++ VGDRV ++P + C QC+ CR  R  LC N+        +G    Y
Sbjct:  64 SGVVAEIGSDVTNVAVGDRVTIDPNIYCGQCKYCRTARPELCENLSAVGVTR-NGGFEEY 122

Query: 146 VCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVA 205
              PA+  Y++P++VSL+  A+ EP+S AVH  +    T     LV+G G +G L   + 
Sbjct: 123 FTAPASVVYQIPDNVSLKSAAVVEPISCAVHGIQLLKVTPYQKALVIGDGFMGELFVQIL 182

Query: 206 KAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDC 265
           +A+G   + +  I   +LA  +   G     NT+D D+          +     D+ ++ 
Sbjct: 183 QAYGIHQVDLAGIVPEKLAMNKEKFGVKNTYNTKDGDK----------IPEGTYDVVVEA 232

Query: 266 AGLESTMRLAMHVVRPGGRICLVGMG--SSAMHVPLVDASSREIDIFGVFRYSNTYPTCI 323
            GL  T   A+     G ++ + G+G   +   +   +   +++ I G F   N +   +
Sbjct: 233 VGLPQTQEAAIEASARGAQVLMFGVGGPDAKFQMNTYEVFQKQLTIQGSFINPNAFEDSL 292

Query: 324 ALLASGRVNVKPLITHRF 341
           ALL+SG+++V+ L++H  
Sbjct: 293 ALLSSGKLDVESLMSHEL 310

ref|YP_119286.1| putative dehydrogenase [Nocardia farcinica IFM 10152]
dbj|BAD57922.1| putative dehydrogenase [Nocardia farcinica IFM 10152]
(351 aa)

Score: 149 bits (377), Expect: 1.07187e-34
Length: 311, Idn/Pos/Gap = 107/149/14 (34%/47%/4%)

Query:  30 PRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCG-PFRLHD------PMIIG  82
           P ++ V+    P P PGEV+L++   GICG+D+H ++ G    P   H       P+++G
Sbjct:   9 PNKVDVVDVPEPEPGPGEVKLRVGFNGICGTDLHEYYAGPIFVPTEPHPLTHRQLPLVLG  68

Query:  83 HESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSL 142
           HE +G V  +G+GVT ++ GDRVA+EP   C  C  CR G YN+C  I F      DG +
Sbjct:  69 HEFSGTVTEVGSGVTGIEPGDRVAVEPLYTCGHCGPCRAGTYNICRRIGFHGLMS-DGGM 127

Query: 143 ARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNC 202
           A Y   PA   +RLP+SV LE GA+ EP+SVA HA            +V GAGPIG+   
Sbjct: 128 AEYTVVPAHMIHRLPDSVPLELGALVEPMSVAYHAATLGDPKPEDTAMVFGAGPIGIGLW 187

Query: 203 MVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIA 262
              +A G   I V +    R A  E          T D    D    +  A DGA AD  
Sbjct: 188 FALRAKGLDDIYVVEPSPTRRAAIEALGA-----TTLDPTAVDVPAFIDNATDGAGADAT 242

Query: 263 LDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNT-YPT 321
            D AG++  +  A+  +     +  V +    +  PL      E  I G   Y++  Y  
Sbjct: 243 YDAAGVQPAVETALACLGARRPLISVAIYEKPLTTPLQRLVMNESRIQGSLCYTSADYRA 302

Query: 322 CIALLASGRVN 332
            I L+A GR +
Sbjct: 303 VIDLMAQGRYD 313

ref|YP_087717.1| Tdh protein [Mannheimia succiniciproducens MBEL55E]
gb|AAU37132.1| Tdh protein [Mannheimia succiniciproducens MBEL55E]
(335 aa)

Score: 149 bits (376), Expect: 1.21478e-34
Length: 318, Idn/Pos/Gap = 99/160/16 (31%/50%/5%)

Query:  26 VLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHES  85
           V   P  L +  R+ P P   EV+L++  +GICG+D+H +      PF    P ++GHE+
Sbjct:   6 VCKEPFHLILEERAKPQPKDEEVQLKVAAIGICGTDIHAY--AGNQPF-FEYPRVLGHEA  62

Query:  86 AGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARY 145
           +GV+  LG  V   +VG RVAL P V C +C  C  G+ N C NI        DG+ + Y
Sbjct:  63 SGVITELGKNVDKFKVGQRVALIPYVSCGKCGACLSGKTNCCENISVIGVHQ-DGAFSEY 121

Query: 146 VCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVA 205
           +  PA     + +SV     A+ EP +++ HA RRA  T G  VL++GAGPIGL    +A
Sbjct: 122 LTAPAKNILPIADSVDFTTAALIEPFAISAHAVRRAQITKGDDVLIVGAGPIGLGAAAIA 181

Query: 206 KAFGASIIVVTDIDDRRLAFAETHAGADAVINTRD-LDEHDAALVVQQALDGAQADIALD 264
            A GA++++    ++RR      H  A+  + T + ++E      V+   +G    I +D
Sbjct: 182 HADGANVVIADTSEERR-----KHIQANIPVPTVNPINEK-----VEDYFNGRLPQIVID 231

Query: 265 CAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYS-NTYPTCI 323
             G +  M  A++++R GGRI  VG+    +     D   +E  + G    +   +    
Sbjct: 232 ATGNQKAMNNAVNLIRHGGRIVFVGLHKGTIEFSDPDFHKKETTLMGSRNATLEDFEKVQ 291

Query: 324 ALLASGRVNVKPLITHRF 341
            L++  +++   ++TH F
Sbjct: 292 HLMSERKISANMMLTHTF 309

gb|AAK04995.1| 2,3-butanediol dehydrogenase (EC 1.1.1.4) [Lactococcus lactis subsp. lactis Il1403]
pir||A86737 (R,R)-butanediol dehydrogenase (EC 1.1.1.4) [imported] - Lactococcus lactis subsp. lactis (strain IL1403)
(370 aa)

Score: 149 bits (376), Expect: 1.28784e-34
Length: 348, Idn/Pos/Gap = 106/172/18 (30%/49%/5%)

Query:  32 ELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGS--CGPFRLHD--------PMII  81
           ++R+   + P    G+V + +   GICG+D+H +  G   C P   H         P+ +
Sbjct:  25 DIRIDEINEPIVKAGQVGIDVAWCGICGTDLHEFLDGPIFC-PSAEHPNPITGEVPPVTL  83

Query:  82 GHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGS 141
           GHE +GVV  +G GV+ L+VGD V +EP +          G YNL     F       G 
Sbjct:  84 GHEMSGVVNFIGEGVSGLKVGDHVVVEPYIVPEGTDTSETGHYNLSEGSNFIGLGGNGGG 143

Query: 142 LARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLN 201
           LA  +     W +++P+++ L+E A+ EPLSV  HA  RA  +  S VLV+GAGPIGLL 
Sbjct: 144 LAEKISVDERWVHKIPDNLPLDEAALIEPLSVGYHAVERANLSEKSTVLVVGAGPIGLLT 203

Query: 202 CMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADI 261
             VAKA G ++I+      RR    E    AD   N     E D    V + ++    D 
Sbjct: 204 AAVAKAQGHTVIISEPSGLRRKKAQEAQV-ADYFFNPI---EDDIQAKVHE-INEKGVDA 258

Query: 262 ALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPT 321
           A +C  ++      +  +R GG + +V +      V +     +E ++ G   Y+NT+P 
Sbjct: 259 AFECTSVQPGFDACLDAIRMGGTVVIVAIWGKPASVDMAKLVIKEANLLGTIAYNNTHPK 318

Query: 322 CIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLT 369
            I L+++G++ +   IT + +GL++  ++  F+T       AVK++++
Sbjct: 319 TIDLVSTGKIKLDQFITAK-IGLDD-LIDKGFDTLIHHNETAVKILVS 364

ref|NP_267053.2| 2,3-butanediol dehydrogenase [Lactococcus lactis subsp. lactis Il1403]
(356 aa)

Score: 149 bits (376), Expect: 1.38827e-34
Length: 348, Idn/Pos/Gap = 106/172/18 (30%/49%/5%)

Query:  32 ELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGS--CGPFRLHD--------PMII  81
           ++R+   + P    G+V + +   GICG+D+H +  G   C P   H         P+ +
Sbjct:  11 DIRIDEINEPIVKAGQVGIDVAWCGICGTDLHEFLDGPIFC-PSAEHPNPITGEVPPVTL  69

Query:  82 GHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGS 141
           GHE +GVV  +G GV+ L+VGD V +EP +          G YNL     F       G 
Sbjct:  70 GHEMSGVVNFIGEGVSGLKVGDHVVVEPYIVPEGTDTSETGHYNLSEGSNFIGLGGNGGG 129

Query: 142 LARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLN 201
           LA  +     W +++P+++ L+E A+ EPLSV  HA  RA  +  S VLV+GAGPIGLL 
Sbjct: 130 LAEKISVDERWVHKIPDNLPLDEAALIEPLSVGYHAVERANLSEKSTVLVVGAGPIGLLT 189

Query: 202 CMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADI 261
             VAKA G ++I+      RR    E    AD   N     E D    V + ++    D 
Sbjct: 190 AAVAKAQGHTVIISEPSGLRRKKAQEAQV-ADYFFNPI---EDDIQAKVHE-INEKGVDA 244

Query: 262 ALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPT 321
           A +C  ++      +  +R GG + +V +      V +     +E ++ G   Y+NT+P 
Sbjct: 245 AFECTSVQPGFDACLDAIRMGGTVVIVAIWGKPASVDMAKLVIKEANLLGTIAYNNTHPK 304

Query: 322 CIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLT 369
            I L+++G++ +   IT + +GL++  ++  F+T       AVK++++
Sbjct: 305 TIDLVSTGKIKLDQFITAK-IGLDD-LIDKGFDTLIHHNETAVKILVS 350

ref|YP_134451.1| zinc-binding dehydrogenase [Haloarcula marismortui ATCC 43049]
gb|AAV44745.1| zinc-binding dehydrogenase [Haloarcula marismortui ATCC 43049]
(344 aa)

Score: 149 bits (375), Expect: 1.50907e-34
Length: 314, Idn/Pos/Gap = 113/161/19 (35%/51%/6%)

Query:  47 EVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGDRVA 106
           EV +Q+    +C +D H + HG+   F    P+++GHE AG V  +GA V    VGDRVA
Sbjct:  26 EVLVQVGACSVCMTDYHMY-HGT---FAAETPLVLGHEGAGTVAEVGADVDRFAVGDRVA  81

Query: 107 LEPGVPCLQCQRCREGRYNLCPN---IKFFATPPVDGSLARYVCHPAAWCYRLPESVSLE 163
           + P VPC  C  C++G  +LC N   I       +DG+ A YV  PA     + E +S E
Sbjct:  82 INPTVPCNACSYCKKGETHLCENNTSIGGAGDTILDGAFAEYVRVPAINVEDIGE-MSFE 140

Query: 164 EGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRL 223
             A+ EPL+  VH   +A    G  V ++GAGPIGLL     +  GA+ IVV+++DD R 
Sbjct: 141 RAALAEPLACCVHGVEQADIKPGDSVGIIGAGPIGLLLLQAFRNAGAAPIVVSELDDERR 200

Query: 224 AFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVVRPGG 283
             A    GADAVI+  + D  +A      A  G   ++  +  GL  T++ A  V  PGG
Sbjct: 201 ELA-ADLGADAVIDPNEEDPEEAI----PAAAGGPVNVGAEAIGLVPTIKQANAVTAPGG 255

Query: 284 RICLVGM--GSSAMHVPLVDASSREIDIFGVFRYSNT-YPTCIALLASGRVNVKPLITHR 340
              + G+    + M V   D    E+D  G F  +   +   I LL   R++ + LIT R
Sbjct: 256 STLIFGVPDQEATMEVSPFDVFFDEVDYRGSFSLTTEDFERAITLLRHERIDAETLITER 315

Query: 341 FMGLEESSLEAAFE 354
            +GL++  L AAFE
Sbjct: 316 -IGLDD--LPAAFE 326

ref|NP_693674.1| sorbitol dehydrogenase [Oceanobacillus iheyensis HTE831]
dbj|BAC14708.1| sorbitol dehydrogenase (L-iditol 2-dehydrogenase) [Oceanobacillus iheyensis HTE831]
(344 aa)

Score: 149 bits (375), Expect: 1.8591e-34
Length: 335, Idn/Pos/Gap = 106/171/24 (31%/51%/7%)

Query:  41 PAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQ 100
           P+ +  +V++++   GICGSD+H +     G +++  P+ +GHE +G +  +G GVT  +
Sbjct:  22 PSVSSHQVKIKVAYAGICGSDIHTYE----GHYKVAAPVTLGHEFSGRIVEVGEGVTDFK  77

Query: 101 VGDRVALEPGVP-CLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPES 159
           VGDRV  E     C +C+ C+ G YNLC + K   T   +G    Y+       + LP+ 
Sbjct:  78 VGDRVTSETTFSICGECRYCQTGDYNLCNHRKGLGTQQ-NGGFTNYLIAREESLHHLPDE 136

Query: 160 VSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVV-TDI 218
           V     +M EPL+   HA ++     G LV+VLG GPIGLL   VAK++GA++++   D 
Sbjct: 137 VDDRSASMTEPLACTYHAIQKINIKPGDLVVVLGPGPIGLLAAQVAKSYGATVMMSGLDN 196

Query: 219 DDRRLAFAETHAGADAVINTR--DLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAM 276
           D  RL  A+   G D VIN +  D+ E  AAL      DG   D+ L+C+G        +
Sbjct: 197 DKIRLDKAK-EVGIDYVINIQEEDIKEKIAALT-----DGYGVDVVLECSGSIHAANQGL 250

Query: 277 HVVRPGGRICLVGM-GSSAMHVPLVDASSREIDIFGV-FRYSNTYPTCIALLASGRVNVK 334
            ++R  G    VG+   S +   +     +EI + G   + S  +   + L+   +V+ K
Sbjct: 251 DLLRKKGSYAQVGIFPDSHVKFDMEKVIQKEIHVVGSRSQKSADWEPSLQLMKEKKVDAK 310

Query: 335 PLITHRFMGLEESSLEAAFETARTAANG-AVKVML 368
            L+TH F      +++   E  +   +G A+KV+L
Sbjct: 311 ALVTHEF------TIDQWDEAYQAIKDGEAIKVLL 339

emb|CAA29884.1| unnamed protein product [Escherichia coli]
gb|AAB18593.1| threonine dehydrogenase [Escherichia coli]
ref|NP_418073.1| threonine 3-dehydrogenase, NAD(P)-binding [Escherichia coli K12]
gb|AAC76640.1| threonine dehydrogenase; threonine 3-dehydrogenase, NAD(P)-binding [Escherichia coli K12]
pir||DEECTH L-threonine 3-dehydrogenase (EC 1.1.1.103) - Escherichia coli (strain K-12)
sp|P07913|TDH_ECOLI L-threonine 3-dehydrogenase
(341 aa)

Score: 148 bits (374), Expect: 2.16037e-34
Length: 340, Idn/Pos/Gap = 104/170/26 (30%/50%/7%)

Query:  35 VMLRSVPAPAPG--EVRLQMRCVGICGSDVHYW----WHGSCGPFRLHDPMIIGHESAGV  88
           + +  VP P  G  ++ +++R   ICG+DVH +    W     P     PM++GHE  G 
Sbjct:  13 IWMTDVPVPELGHNDLLIKIRKTAICGTDVHIYNWDEWSQKTIPV----PMVVGHEYVGE  68

Query:  89 VEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPN-IKFFATPPVDGSLARYVC 147
           V  +G  V   ++GDRV+ E  + C  C+ CR GR +LC N I      P  G  A Y+ 
Sbjct:  69 VVGIGQEVKGFKIGDRVSGEGHITCGHCRNCRGGRTHLCRNTIGVGVNRP--GCFAEYLV 126

Query: 148 HPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKA 207
            PA   +++P+++S +  A+ +P   AVH    +   +G  VLV GAGPIG++   VAK 
Sbjct: 127 IPAFNAFKIPDNISDDLAAIFDPFGNAVH-TALSFDLVGEDVLVSGAGPIGIMAAAVAKH 185

Query: 208 FGASIIVVTDIDDRRLAFAETHAGADAV-INTRDLDEHDAALVVQQALDGAQADIALDCA 266
            GA  +V+TD+++ RL  A       AV +   +L++  A L + +       D+ L+ +
Sbjct: 186 VGARNVVITDVNEYRLELARKMGITRAVNVAKENLNDVMAELGMTEGF-----DVGLEMS 240

Query: 267 GLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVF--RYSNTYPTCIA 324
           G     R  +  +  GGRI ++G+  S M +       + + I G++      T+    A
Sbjct: 241 GAPPAFRTMLDTMNHGGRIAMLGIPPSDMSIDWTKVIFKGLFIKGIYGREMFETWYKMAA 300

Query: 325 LLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAV 364
           L+ SG +++ P+ITHRF        +  F+  R+  +G V
Sbjct: 301 LIQSG-LDLSPIITHRF---SIDDFQKGFDAMRSGQSGKV 336

ref|YP_068606.1| threonine 3-dehydrogenase [Yersinia pseudotuberculosis IP 32953]
emb|CAH19297.1| threonine 3-dehydrogenase [Yersinia pseudotuberculosis IP 32953]
(341 aa)

Score: 148 bits (373), Expect: 2.70624e-34
Length: 340, Idn/Pos/Gap = 105/174/26 (30%/51%/7%)

Query:  35 VMLRSVPAPAPG--EVRLQMRCVGICGSDVHYW----WHGSCGPFRLHDPMIIGHESAGV  88
           + +  VP P  G  ++ +++R   ICG+DVH +    W     P     PM++GHE  G 
Sbjct:  13 IWMTDVPQPELGHNDIMIKIRKTAICGTDVHIYNWDEWSQKTIPV----PMVVGHEYVGE  68

Query:  89 VEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPN-IKFFATPPVDGSLARYVC 147
           V A+G  V    +GDRV+ E  + C  C+ CR GR +LC N +      P  GS A Y+ 
Sbjct:  69 VVAIGQEVKGFNIGDRVSGEGHITCGHCRNCRGGRTHLCRNTVGVGVNRP--GSFAEYLV 126

Query: 148 HPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKA 207
            PA   +++P+++S E  A+ +P   AVH    +   +G  VLV GAGPIG++   V K 
Sbjct: 127 IPAFNAFKIPDNISDELAAIFDPFGNAVH-TALSFDLVGEDVLVSGAGPIGIMAAAVCKH 185

Query: 208 FGASIIVVTDIDDRRLAFAETHAGADAV-INTRDLDEHDAALVVQQALDGAQADIALDCA 266
            GA  +V+TD+++ RL  A       AV ++  +L++    L + +       D+ L+ +
Sbjct: 186 VGARHVVITDVNEYRLDLARKMGVTRAVNVSKENLNDVMTELGMTEGF-----DVGLEMS 240

Query: 267 GLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVF--RYSNTYPTCIA 324
           G     R  ++ +  GGRI ++G+  S M +       + + I G++      T+    A
Sbjct: 241 GAPPAFRSLLNSMNHGGRIAMLGIPPSDMSIDWNQVIFKGLFIKGIYGREMFETWYKMAA 300

Query: 325 LLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAV 364
           L+ SG +++ P+ITHRF  ++E   +  F+  R+  +G V
Sbjct: 301 LIQSG-LDLTPIITHRF-PIDE--FQQGFDAMRSGKSGKV 336

ref|XP_510365.1| PREDICTED: hypothetical protein XP_510365 [Pan troglodytes]
(513 aa)

Score: 148 bits (373), Expect: 2.94173e-34
Length: 225, Idn/Pos/Gap = 90/127/25 (40%/56%/11%)

Query: 156 LPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVV 215
           LP++V+ EEGA+ +PLSV +HA RR G T+G  VLV GAG IG++  +VAKA GA+ +VV
Sbjct: 287 LPDNVTFEEGALIDPLSVGIHACRRGGVTLGHKVLVCGAGAIGVVTLLVAKAMGAAQVVV 346

Query: 216 TDIDDRRLAFAET------------------HAGADAVINTRDLDEHDAALVVQQALDGA 257
           T      ++  ET                    GAD V         + A  ++  L G 
Sbjct: 347 TGKTLFFISPLETGKQLVLLICLLPDCPKPRSIGADLVPQISKESPQEIARKIEGLL-GC 405

Query: 258 QADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSN 317
           + ++ ++C G E++++  ++  R GG + LVG+GS    VPL+ A+  E+DI GVFRY N
Sbjct: 406 KPEVTIECTGAETSIQAGIYATRSGGTLVLVGLGSEMTTVPLLHAAVWEVDIKGVFRYCN 465

Query: 318 TYPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANG 362
           T+P  I++LAS  VNVKPL+THRF       LE A E   T   G
Sbjct: 466 TWPVAISMLASKSVNVKPLVTHRF------PLEKALEAFETFKKG 504


Score: 121 bits (304), Expect: 2.66763e-26
Length: 148, Idn/Pos/Gap = 63/84/22 (42%/56%/14%)

Query:  30 PRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVV  89
           P +LR+    +P P P EV L+M  VGICGSDVH+W  G  G F +  PM++GHE++G V
Sbjct:  58 PGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHFWEDGRIGNFIVKKPMVLGHEASGTV 117

Query:  90 EALGAGVTSLQV----------------------GDRVALEPGVPCLQCQRCREGRYNLC 127
           E +G+ V   +                       GDRVA+EPG P    + C+ GRYNL 
Sbjct: 118 EKVGSSVGKQRTGPKRRQTLLPPSDMVPSLFSSPGDRVAIEPGAPRENDEFCKMGRYNLS 177

Query: 128 PNIKFFATPPVDGSLARYVCHPAAWCYR 155
           P+I F ATPP D +L R+  H AA+CY+
Sbjct: 178 PSIFFCATPPDDRNLCRFYKHNAAFCYK 205

gb|AAX77890.1| unknown protein [synthetic construct]
(386 aa)

Score: 148 bits (373), Expect: 3.25152e-34
Length: 342, Idn/Pos/Gap = 102/172/24 (29%/50%/7%)

Query:  36 MLRSVPAPAPG--EVRLQMRCVGICGSDVHYW----WHGSCGPFRLHDPMIIGHESAGVV  89
           ++   P P  G  +V ++++   ICG+D+H +    W  +  P     PMI GHE AG V
Sbjct:  41 IINDAPIPEYGYNDVLIKIKKTAICGTDLHIYNWDKWSQNTIPV----PMITGHEFAGEV  96

Query:  90 EALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHP 149
            A G GVTS+ +GDRV+ E  + C QC+ CR G+ +LC          V G+ A Y+  P
Sbjct:  97 VAKGDGVTSVDIGDRVSGEGHLVCGQCRNCRAGKRHLCRKTIGIGV-NVQGAFAEYLVMP 155

Query: 150 AAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFG 209
           A   +++P+S+S +  +  +P+  A+H       T G  VL+ GAGPIGL+   +A+  G
Sbjct: 156 AVNVFKIPDSISDDIASTFDPMGNAIHTALSFNLT-GEDVLITGAGPIGLMAVKIARFCG 214

Query: 210 ASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAAL-----VVQQALDGAQADIALD 264
           A  IV+TDI++ RL  A    GA   +N       D  +     V+         D+ L+
Sbjct: 215 ARRIVITDINEYRLQMARDF-GATVALNVAPFKNQDELVKQMRKVMSDIGMTEGFDVGLE 273

Query: 265 CAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVF--RYSNTYPTC 322
            +G+ S + + + V+  GG++ L+G+ +  + V       + + + G++      T+   
Sbjct: 274 MSGINSAISMMLDVMNHGGKLSLLGISAGDISVDWGAILFKGLTLKGIYGREMFETWYLM 333

Query: 323 IALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAV 364
            ++L +G +++ P+ITHR   L     +  FE  ++   G V
Sbjct: 334 TSMLQAG-MDMNPIITHR---LHIDEFQKGFEIMKSGQCGKV 371

ref|NP_931999.1| threonine 3-dehydrogenase [Photorhabdus luminescens subsp. laumondii TTO1]
emb|CAE17217.1| threonine 3-dehydrogenase [Photorhabdus luminescens subsp. laumondii TTO1]
(341 aa)

Score: 147 bits (372), Expect: 4.17634e-34
Length: 334, Idn/Pos/Gap = 103/168/24 (30%/50%/7%)

Query:  40 VPAPAPG--EVRLQMRCVGICGSDVHYW----WHGSCGPFRLHDPMIIGHESAGVVEALG  93
           VP P  G  +V +++R   ICG+DVH +    W     P     PM++GHE  G V A+G
Sbjct:  18 VPEPELGHNDVMIKIRKTAICGTDVHIYNWDDWSQKTIPV----PMVVGHEYVGEVVAIG  73

Query:  94 AGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWC 153
             V   ++GDRV+ E  + C  C+ CR GR +LC N          G  A+Y+  PA   
Sbjct:  74 QEVKGFKIGDRVSGEGHITCGYCRNCRGGRTHLCRNTIGVGVNRA-GCFAQYLVIPAFNA 132

Query: 154 YRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASII 213
           +++P+++S E  A+ +P   AVH    +   +G  VLV GAGPIG++   V K  GA  +
Sbjct: 133 FKIPDNISDELAAIFDPFGNAVH-TALSFDLVGEDVLVSGAGPIGIMAAAVCKHVGARHV 191

Query: 214 VVTDIDDRRLAFAETHAGADAV-INTRDLDEHDAALVVQQALDGAQADIALDCAGLESTM 272
           V+TD+++ RL  A       AV ++  +L +  A L + +       D+ L+ +G  +  
Sbjct: 192 VITDVNEYRLELARKMGVTRAVNVSQENLTDVMAELGMTEGF-----DVGLEMSGAPAAF 246

Query: 273 RLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVF--RYSNTYPTCIALLASGR 330
           R  ++ +  GGR+ L+G+  S M +       + + I G++      T+     L+ SG 
Sbjct: 247 RTLLNTMNHGGRVALLGIPPSDMAIDWNQVIFKGLFIKGIYGREMFETWYKMATLIQSG- 305

Query: 331 VNVKPLITHRFMGLEESSLEAAFETARTAANGAV 364
           +++ P+ITHRF        +  F+  R+  +G V
Sbjct: 306 LDLTPIITHRF---SIDDFQKGFDIMRSGQSGKV 336

sp|Q9RTU4|TDH_DEIRA L-threonine 3-dehydrogenase
(348 aa)

Score: 147 bits (371), Expect: 4.50203e-34
Length: 309, Idn/Pos/Gap = 98/157/18 (31%/50%/5%)

Query:  40 VPAPAPGEVRLQMRCVGICGSDVHYW----WHGSCGPFRLHDPMIIGHESAGVVEALGAG  95
           VP P P ++ +++R   ICG+DVH +    W     P     PM++GHE  GVV  +G+ 
Sbjct:  20 VPTPGPNDLLIRIRKGSICGTDVHIYKWDDWASQTVPV----PMVVGHEYVGVVAGMGSE  75

Query:  96 VTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYR 155
           V   ++GDRV+ E  V C  C+ CR GR +LC N +        GS A Y+  PA   ++
Sbjct:  76 VRGFEIGDRVSGEGHVTCGHCRNCRAGRRHLCRNTQGVGVNR-PGSFAEYLVLPAFNAFK 134

Query: 156 LPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVV 215
           LP+ +  +  A+ +P   AVH    +   +G  VL+ GAGPIG +   VA+  GA  +V+
Sbjct: 135 LPDDIPDDVAAIFDPFGNAVH-TALSFDLVGEDVLITGAGPIGCMAAAVARHVGARNVVI 193

Query: 216 TDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQA-DIALDCAGLESTMRL 274
           TD++D RL  A       AV   R+    D   V  Q LD  +  D+ ++ +G       
Sbjct: 194 TDVNDYRLDLARQMGVTRAVNVARE----DLWTVATQELDMHEGFDVGMEMSGSGPAFAQ 249

Query: 275 AMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVF--RYSNTYPTCIALLASGRVN 332
            + V+  GG++ L+G+ S  + +       + + I G++      T+    AL+ SG ++
Sbjct: 250 MVSVMNNGGKVALLGIPSGEVQIDWNAVIFKMLTIKGIYGREMFETWYKMAALIQSG-LD 308

Query: 333 VKPLITHRF 341
           + P+ITH +
Sbjct: 309 LTPVITHHY 317

gb|AAF11215.1| threonine 3-dehydrogenase [Deinococcus radiodurans]
pir||A75371 threonine 3-dehydrogenase - Deinococcus radiodurans (strain R1)
ref|NP_295385.1| threonine 3-dehydrogenase [Deinococcus radiodurans R1]
(370 aa)

Score: 147 bits (371), Expect: 5.01783e-34
Length: 309, Idn/Pos/Gap = 98/157/18 (31%/50%/5%)

Query:  40 VPAPAPGEVRLQMRCVGICGSDVHYW----WHGSCGPFRLHDPMIIGHESAGVVEALGAG  95
           VP P P ++ +++R   ICG+DVH +    W     P     PM++GHE  GVV  +G+ 
Sbjct:  42 VPTPGPNDLLIRIRKGSICGTDVHIYKWDDWASQTVPV----PMVVGHEYVGVVAGMGSE  97

Query:  96 VTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYR 155
           V   ++GDRV+ E  V C  C+ CR GR +LC N +        GS A Y+  PA   ++
Sbjct:  98 VRGFEIGDRVSGEGHVTCGHCRNCRAGRRHLCRNTQGVGVNR-PGSFAEYLVLPAFNAFK 156

Query: 156 LPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVV 215
           LP+ +  +  A+ +P   AVH    +   +G  VL+ GAGPIG +   VA+  GA  +V+
Sbjct: 157 LPDDIPDDVAAIFDPFGNAVH-TALSFDLVGEDVLITGAGPIGCMAAAVARHVGARNVVI 215

Query: 216 TDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQA-DIALDCAGLESTMRL 274
           TD++D RL  A       AV   R+    D   V  Q LD  +  D+ ++ +G       
Sbjct: 216 TDVNDYRLDLARQMGVTRAVNVARE----DLWTVATQELDMHEGFDVGMEMSGSGPAFAQ 271

Query: 275 AMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVF--RYSNTYPTCIALLASGRVN 332
            + V+  GG++ L+G+ S  + +       + + I G++      T+    AL+ SG ++
Sbjct: 272 MVSVMNNGGKVALLGIPSGEVQIDWNAVIFKMLTIKGIYGREMFETWYKMAALIQSG-LD 330

Query: 333 VKPLITHRF 341
           + P+ITH +
Sbjct: 331 LTPVITHHY 339

ref|YP_169728.1| L-threonine 3-dehydrogenase [Francisella tularensis subsp. tularensis Schu 4]
emb|CAG45346.1| L-threonine 3-dehydrogenase [Francisella tularensis subsp. tularensis SCHU S4]
(351 aa)

Score: 147 bits (371), Expect: 5.01783e-34
Length: 342, Idn/Pos/Gap = 102/172/24 (29%/50%/7%)

Query:  36 MLRSVPAPAPG--EVRLQMRCVGICGSDVHYW----WHGSCGPFRLHDPMIIGHESAGVV  89
           ++   P P  G  +V ++++   ICG+D+H +    W  +  P     PMI GHE AG V
Sbjct:  15 IINDAPIPEYGYNDVLIKIKKTAICGTDLHIYNWDKWSQNTIPV----PMITGHEFAGEV  70

Query:  90 EALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHP 149
            A G GVTS+ +GDRV+ E  + C QC+ CR G+ +LC          V G+ A Y+  P
Sbjct:  71 VAKGDGVTSVDIGDRVSGEGHLVCGQCRNCRAGKRHLCRKTIGIGV-NVQGAFAEYLVMP 129

Query: 150 AAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFG 209
           A   +++P+S+S +  +  +P+  A+H       T G  VL+ GAGPIGL+   +A+  G
Sbjct: 130 AVNVFKIPDSISDDIASTFDPMGNAIHTALSFNLT-GEDVLITGAGPIGLMAVKIARFCG 188

Query: 210 ASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAAL-----VVQQALDGAQADIALD 264
           A  IV+TDI++ RL  A    GA   +N       D  +     V+         D+ L+
Sbjct: 189 ARRIVITDINEYRLQMARDF-GATVALNVAPFKNQDELVKQMRKVMSDIGMTEGFDVGLE 247

Query: 265 CAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVF--RYSNTYPTC 322
            +G+ S + + + V+  GG++ L+G+ +  + V       + + + G++      T+   
Sbjct: 248 MSGINSAISMMLDVMNHGGKLSLLGISAGDISVDWGAILFKGLTLKGIYGREMFETWYLM 307

Query: 323 IALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAV 364
            ++L +G +++ P+ITHR   L     +  FE  ++   G V
Sbjct: 308 TSMLQAG-MDMNPIITHR---LHIDEFQKGFEIMKSGQCGKV 345

ref|NP_709396.1| threonine dehydrogenase [Shigella flexneri 2a str. 301]
gb|AAN45103.1| threonine dehydrogenase [Shigella flexneri 2a str. 301]
ref|NP_839277.1| threonine dehydrogenase [Shigella flexneri 2a str. 2457T]
gb|AAP19088.1| threonine dehydrogenase [Shigella flexneri 2a str. 2457T]
sp|P59409|TDH_SHIFL L-threonine 3-dehydrogenase
(341 aa)

Score: 147 bits (371), Expect: 5.10226e-34
Length: 340, Idn/Pos/Gap = 103/170/26 (30%/50%/7%)

Query:  35 VMLRSVPAPAPG--EVRLQMRCVGICGSDVHYW----WHGSCGPFRLHDPMIIGHESAGV  88
           + +  VP P  G  ++ +++R   ICG+DVH +    W     P     PM++GHE  G 
Sbjct:  13 IWMTDVPVPELGHNDLLIKIRKTAICGTDVHIYNWDEWSQKTIPV----PMVVGHEYVGE  68

Query:  89 VEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPN-IKFFATPPVDGSLARYVC 147
           V  +G  V   ++GDRV+ E  + C  C+ CR GR +LC N I      P  G  A Y+ 
Sbjct:  69 VVGIGQEVKGFKIGDRVSGEGHITCGHCRNCRGGRTHLCRNTIGVGVNRP--GCFAEYLV 126

Query: 148 HPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKA 207
            PA   +++P+++S +  ++ +P   AVH    +   +G  VLV GAGPIG++   VAK 
Sbjct: 127 IPAFNAFKIPDNISDDLASIFDPFGNAVH-TALSFDLVGEDVLVSGAGPIGIMAAAVAKH 185

Query: 208 FGASIIVVTDIDDRRLAFAETHAGADAV-INTRDLDEHDAALVVQQALDGAQADIALDCA 266
            GA  +V+TD+++ RL  A       AV +   +L++  A L + +       D+ L+ +
Sbjct: 186 VGARNVVITDVNEYRLELARKMGITRAVNVAKENLNDVMAELGMTEGF-----DVGLEMS 240

Query: 267 GLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVF--RYSNTYPTCIA 324
           G     R  +  +  GGRI ++G+  S M +       + + I G++      T+    A
Sbjct: 241 GAPPAFRTMLDTMNHGGRIAMLGIPPSDMSIDWTKVIFKGLFIKGIYGREMFETWYKMAA 300

Query: 325 LLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAV 364
           L+ SG +++ P+ITHRF        +  F+  R+  +G V
Sbjct: 301 LIQSG-LDLSPIITHRF---SIDDFQKGFDAMRSGQSGKV 336

ref|ZP_00200044.1| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Rubrobacter xylanophilus DSM 9941]
(341 aa)

Score: 147 bits (371), Expect: 5.18812e-34
Length: 349, Idn/Pos/Gap = 128/179/28 (36%/51%/8%)

Query:  29 RPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGV  88
           RP E  V     P P PGEV L++   G+CGSDVH +     G   +  P+ +GHE AG 
Sbjct:  10 RPGEAGVAELPAPRPGPGEVLLRVAACGVCGSDVHAF-RSDPGFEWISTPVTLGHEFAGT  68

Query:  89 VEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCH 148
           VEALG GV  +  GDRV       C +C+ C  G   LCP+ +       DG +A Y   
Sbjct:  69 VEALGPGVERVAPGDRVVAVAIQGCGRCELCLAGLTQLCPD-RVAVGLSRDGGMAEYAVM 127

Query: 149 PAAWCYRLPESVSLEEGAMCEPLSVAVHA-NRRAGTTIGSLVLVLGAGPIGLLNCMVAKA 207
           P      +PE + L   A+CEPLSVAV A + RAG      V+V G GPIG+L  MVA+ 
Sbjct: 128 PEGHLVSVPEGLDLTLAALCEPLSVAVRAVDARAGIAPEGKVVVSGPGPIGILCAMVARL 187

Query: 208 FGASIIVVTDIDDR--RLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDC 265
            GA +++     D   RL  AE      A ++   L+EH     ++ A  G   D+ ++ 
Sbjct: 188 RGADVLLTGIGQDAEVRLPAAERAGIRAANLSEASLEEH-----LRDAF-GRPPDVWIES 241

Query: 266 AGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYS---NTYPTC 322
           +G    +  A+  VR GG + +VG+ +  +++   DA  RE+ +  +F YS     Y T 
Sbjct: 242 SGSVRALESALESVRAGGTVVVVGIYAERLNLFPTDAVRRELSL--LFSYSCNLADYRTA 299

Query: 323 IALLASGRVNVKPLI-THRFMGLEES--SLEAAFETARTAANGAVKVML 368
           + LLASG +++ PLI THR   LEE+  +LEA       AA   VK +L
Sbjct: 300 LELLASGDLDLGPLISTHR---LEEAPDALEA------VAAGRTVKAVL 339

ref|ZP_00132861.2| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Haemophilus somnus 2336]
(352 aa)

Score: 147 bits (370), Expect: 5.83098e-34
Length: 320, Idn/Pos/Gap = 99/170/25 (30%/53%/7%)

Query:  27 LVRPRELRVMLRSVPAPAPGE--VRLQMRCVGICGSDVHYWWHGSCGPFRLHDPM-----  79
           LV P+  +V +++V  P  GE  V +++  +GICGSD+        G FR  +P+     
Sbjct:  21 LVEPK--KVDIKTVLYPKKGECDVLIKVESIGICGSDI--------GAFRGTNPLVTYPR  70

Query:  80 IIGHESAGVVEALGAGV-TSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPV 138
           I+GHE  G V   G G+  ++ +GDRV LEP + C  C  C   R N C  +K      +
Sbjct:  71 ILGHEIVGTVIEAGVGMPKNINIGDRVILEPYIYCGHCYPCSISRTNCCEALKVLGVH-I 129

Query: 139 DGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIG 198
           DG++   V HPA    + P+ + + E A+ EPL++++HA RR     G  V ++GAG IG
Sbjct: 130 DGAMQEIVRHPAHMLIKAPD-IPIHELALAEPLTISLHAIRRTKVKAGEHVAIIGAGAIG 188

Query: 199 LLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQ 258
           L+  +VAKA+GA+ I++ DI D+RL +A++  G   +IN    ++ +A   ++   +G  
Sbjct: 189 LMAALVAKAYGATPILI-DILDKRLDYAKS-IGIPNIINPAKENDLEA---IKSITNGRM 243

Query: 259 ADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNT 318
           A++ ++ +G    ++  +      GRI L G   +   +P    + +E++I+G       
Sbjct: 244 AEVVIEASGANIAVQNTLKYTSFAGRIALTGWPKNETPLPTNLITFKELNIYGARTSKGE 303

Query: 319 YPTCIALLASGRVNVKPLIT 338
           +   + LL S ++  K +I+
Sbjct: 304 FEEALKLLESRKIEPKNIIS 323

ref|YP_048295.1| L-threonine 3-dehydrogenase [Erwinia carotovora subsp. atroseptica SCRI1043]
emb|CAG73087.1| L-threonine 3-dehydrogenase [Erwinia carotovora subsp. atroseptica SCRI1043]
(361 aa)

Score: 147 bits (370), Expect: 5.87983e-34
Length: 346, Idn/Pos/Gap = 106/171/25 (30%/49%/7%)

Query:  28 VRPRELRVMLRSVPAPAPG--EVRLQMRCVGICGSDVHYW----WHGSCGPFRLHDPMII  81
           +RP E  + +   P P  G  ++ +++R   ICG+DVH +    W     P     PM++
Sbjct:   7 LRPEE-GIWMMDAPMPELGHNDIMIKIRKSAICGTDVHIYNWDEWSQKTIPV----PMVV  61

Query:  82 GHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPN-IKFFATPPVDG 140
           GHE  G + A+G  V    +GDRV+ E  + C  C+ CR GR +LC N I      P  G
Sbjct:  62 GHEYVGEIVAIGQEVNGFHIGDRVSGEGHITCGYCRNCRAGRRHLCRNAIGVGVNRP--G 119

Query: 141 SLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLL 200
           S A Y+  PA   +R+P+++S E  A+ +P   AVH    +   +G  VL+ GAGPIG++
Sbjct: 120 SFAEYLVIPAYNAFRIPDNISDELAAIFDPFGNAVH-TALSFDLVGEDVLITGAGPIGMM 178

Query: 201 NCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQAD 260
              V +  GA  +V+TD++  RL  A +  GA   +N  +    D  + +         D
Sbjct: 179 AAAVCRHVGARNVVITDVNAYRLELA-SKMGATRAVNVAEEKLTDVMIELGMT---EGFD 234

Query: 261 IALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVF--RYSNT 318
           I L+ +G  S  R  +  +  GGRI ++G+    M +   +   + + I G++      T
Sbjct: 235 IGLEMSGAPSAFRAMLKAMNHGGRIAMLGIPHEPMSIDWGEVIFKGLFIKGIYGREMFET 294

Query: 319 YPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAV 364
           +    AL+ SG +++ P+ITHRF        +  F+  R+  +G V
Sbjct: 295 WYKMSALIQSG-LDLSPIITHRF---HIDEFQKGFDAMRSGQSGKV 336

ref|ZP_00123079.1| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Haemophilus somnus 129PT]
(352 aa)

Score: 147 bits (370), Expect: 6.66376e-34
Length: 320, Idn/Pos/Gap = 99/170/25 (30%/53%/7%)

Query:  27 LVRPRELRVMLRSVPAPAPGE--VRLQMRCVGICGSDVHYWWHGSCGPFRLHDPM-----  79
           LV P+  +V +++V  P  GE  V +++  +GICGSD+        G FR  +P+     
Sbjct:  21 LVEPK--KVDIKTVLYPKKGECDVLIKVESIGICGSDI--------GAFRGTNPLVTYPR  70

Query:  80 IIGHESAGVVEALGAGV-TSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPV 138
           I+GHE  G V   G G+  ++ +GDRV LEP + C  C  C   R N C  +K      +
Sbjct:  71 ILGHEIVGTVIESGVGMPKNINIGDRVILEPYIYCGHCYPCSISRTNCCEALKVLGVH-I 129

Query: 139 DGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIG 198
           DG++   V HPA    + P+ + + E A+ EPL++++HA RR     G  V ++GAG IG
Sbjct: 130 DGAMQEIVRHPAHMLIKAPD-IPIHELALAEPLTISLHAIRRTKVKAGEHVAIIGAGAIG 188

Query: 199 LLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQ 258
           L+  +VAKA+GA+ I++ DI D+RL +A++  G   +IN    ++ +A   ++   +G  
Sbjct: 189 LMAALVAKAYGATPILI-DILDKRLDYAKS-IGIPNIINPAKENDLEA---IKSITNGRM 243

Query: 259 ADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNT 318
           A++ ++ +G    ++  +      GRI L G   +   +P    + +E++I+G       
Sbjct: 244 AEVVIEASGANIAVQNTLKYTSFAGRIALTGWPKNETPLPTNLITFKELNIYGARTSKGE 303

Query: 319 YPTCIALLASGRVNVKPLIT 338
           +   + LL S ++  K +I+
Sbjct: 304 FEEALKLLESRKIEPKNIIS 323

ref|YP_039708.1| putative zinc-binding dehydrogenase [Staphylococcus aureus subsp. aureus MRSA252]
emb|CAG39271.1| putative zinc-binding dehydrogenase [Staphylococcus aureus subsp. aureus MRSA252]
(347 aa)

Score: 147 bits (370), Expect: 6.83267e-34
Length: 333, Idn/Pos/Gap = 106/167/22 (31%/50%/6%)

Query:  47 EVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGDRVA 106
           +V +++R  GICGSD   +     GP+    P   GHE +GVV+A+G+ VT + VGD+V 
Sbjct:  27 DVIVKVRATGICGSDTSRY--KKMGPYIQGMPF--GHEFSGVVDAIGSDVTHVNVGDKVT  82

Query: 107 LEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPESVSLEEGA 166
             P +PC QC+ C +G Y  C  + F       GS A YV  PA    ++P++V   E A
Sbjct:  83 GCPAIPCYQCEYCLKGEYARCEKL-FVIGSYEPGSFAEYVKLPAQNVLKVPDNVDYIEAA 141

Query: 167 MCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFA 226
           M EP +V  H   ++    G  V V+G G IGLL    A+ FGA+ I+  DID  +L  A
Sbjct: 142 MVEPSAVVAHGFYKSNIQPGMTVAVMGCGSIGLLAIQWARIFGAAHIIAIDIDAHKLDIA 201

Query: 227 ETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVVRPGGRIC 286
            T  GA   IN++  +E+    +     +  Q DIA++ +G + T+   + + + GG + 
Sbjct: 202 -TSLGAHQTINSK--EENLEKFIENHYAN--QIDIAIESSGAKVTIGQILTLPKKGGEVV 256

Query: 287 LVGMGSSAMHVPLVDASS---REIDIFGVFR-YSNTYP-----TCIALLASGRVNVKPLI 337
           L+G+    + +  V        E+ + G +   S+ +P       +  + +  +NVKP+I
Sbjct: 257 LLGIPYDDIEIDRVHFEKILRNELTVCGSWNCLSSNFPGKEWTATLHYMKTKDINVKPII 316

Query: 338 THRFMGLEESSLEAAFETARTAANGAVKVMLTI 370
           +H F+ LE+      F+          KVM TI
Sbjct: 317 SH-FLPLEKGP--ETFDKLVNKKERFDKVMFTI 346

ref|YP_173739.1| Zn-dependent alcohol dehydrogenase [Bacillus clausii KSM-K16]
dbj|BAD62778.1| Zn-dependent alcohol dehydrogenase [Bacillus clausii KSM-K16]
(349 aa)

Score: 146 bits (369), Expect: 7.87395e-34
Length: 339, Idn/Pos/Gap = 108/167/21 (31%/49%/6%)

Query:  25 GVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSC-----GPFRL---H  76
            V  + +++RV  R        +V++++   GICGSD+H + HG        P  +    
Sbjct:   4 AVWYKEKDIRVEEREPAKLGARDVKVRVAWAGICGSDLHEYLHGPVIIPKGEPDPITGGE  63

Query:  77 DPMIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATP 136
            P+ +GHE AGV+E +G  V S Q GDRV + P    L     +    +L     F A  
Sbjct:  64 SPLTLGHEFAGVIEEVGTEVKSFQKGDRVVINP----LFTYGNKPASVDLYDGFSF-AGL 118

Query: 137 PVDGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGP 196
             DG  A +   P    Y+LP++++LEEGA+ EP++VAV A + A    G  V V GAGP
Sbjct: 119 ATDGGFADFAVLPEKNVYKLPDNLTLEEGALVEPMAVAVQAVKEADFKFGQSVAVFGAGP 178

Query: 197 IGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDG 256
           IGL   + AKA GAS I+V D+ + RL  A    GA    N+  +D  +   V     DG
Sbjct: 179 IGLFTIIAAKAAGASKIIVFDLSEERLEKARL-VGATHTFNSGAVDPVEK--VKSLVPDG 235

Query: 257 AQADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYS 316
              D++ + AG+ +T   ++ V +  G + +V + +  +    +D +   + I     Y 
Sbjct: 236 --VDVSFEVAGVNATFNQSIQVAKSRGVVVVVSIFAKPIEFNPMDLTGSGVKITSTLAYE 293

Query: 317 -NTYPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFE 354
              + T I L+A G +N K +IT R     E+ +E+ FE
Sbjct: 294 PEVFQTTIDLMAEGALNPKGVITDRIE--LENIVESGFE 330

ref|YP_185131.1| hexitol dehydrogenase [Staphylococcus aureus subsp. aureus COL]
gb|AAW38790.1| hexitol dehydrogenase [Staphylococcus aureus subsp. aureus COL]
(347 aa)

Score: 146 bits (369), Expect: 9.07391e-34
Length: 333, Idn/Pos/Gap = 105/166/22 (31%/49%/6%)

Query:  47 EVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGDRVA 106
           +V +++R  GICGSD   +     GP+    P   GHE +GVV+A+G+ VT + VGD+V 
Sbjct:  27 DVIIKVRATGICGSDTSRY--KKMGPYIKGMPF--GHEFSGVVDAIGSDVTHVNVGDKVT  82

Query: 107 LEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPESVSLEEGA 166
             P +PC QC+ C +G Y  C  + F       GS A YV  PA    ++P++V   E A
Sbjct:  83 GCPAIPCYQCEYCLKGEYARCEKL-FVIGSYEPGSFAEYVKLPAQNVLKVPDNVDYIEAA 141

Query: 167 MCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFA 226
           M EP +V  H   ++    G  V V+G G IGLL    A+ FGA+ I+  DID  +L  A
Sbjct: 142 MVEPSAVVAHGFYKSNIQPGMTVAVMGCGSIGLLAIQWARIFGAAHIIAIDIDAHKLDIA 201

Query: 227 ETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVVRPGGRIC 286
            T  GA   IN++   E +    ++      Q D+A++ +G + T+   + + + GG + 
Sbjct: 202 -TSLGAHQTINSK---EENLEKFIENHY-ANQIDLAIESSGAKVTIGQILTLPKKGGEVV 256

Query: 287 LVGMGSSAMHVPLVDASS---REIDIFGVFR-YSNTYP-----TCIALLASGRVNVKPLI 337
           L+G+    + +  V        E+ + G +   S+ +P       +  + +  +NVKP+I
Sbjct: 257 LLGIPYDDIEIDRVHFEKILRNELTVCGSWNCLSSNFPGKEWTATLHYMKTKDINVKPII 316

Query: 338 THRFMGLEESSLEAAFETARTAANGAVKVMLTI 370
           +H F+ LE+      F+          KVM TI
Sbjct: 317 SH-FLPLEKGP--ETFDKLVNKKERFDKVMFTI 346

ref|ZP_00319511.1| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Oenococcus oeni PSU-1]
(336 aa)

Score: 146 bits (368), Expect: 9.78154e-34
Length: 317, Idn/Pos/Gap = 94/157/18 (29%/49%/5%)

Query:  26 VLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHES  85
           VL   +++++     P     EV ++ +  GICG+D H  ++G  G      P+++GHE+
Sbjct:   8 VLTAVKDMKIEQVDKPQVKANEVLIETKYAGICGTD-HALYNGLPGSAAAVPPIVLGHEN  66

Query:  86 AGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARY 145
           +GVV  +G  VTS++VGDRV ++P + C  C  CR GR  LC N+        +G L +Y
Sbjct:  67 SGVVSEVGEKVTSVKVGDRVTVDPNIYCGHCFYCRTGRPELCDNLSAVGVTR-NGGLEQY 125

Query: 146 VCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVA 205
              P+   Y++P++VSL+  A  EP+S AVH  +    T     LV+G G +G L   + 
Sbjct: 126 FTAPSTQVYKVPDNVSLKAAATTEPISCAVHGVKLLKLTPYQKALVIGDGFMGQLFVQLL 185

Query: 206 KAFGASIIVVTDIDDRRLAFAETHAGADAVIN-TRDLDEHDAALVVQQALDGAQADIALD 264
           +A+G   +    I D +LA  +   G     N TRD    D              D+ ++
Sbjct: 186 RAYGVHQVDFAGIIDEKLALNKEKFGVTNTYNTTRDKIPAD-------------YDVVIE 232

Query: 265 CAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPL--VDASSREIDIFGVFRYSNTYPTC 322
             GL  T   A++    G ++ + G+G       +   +   +++ I G F   N +   
Sbjct: 233 AVGLPETQEQAVNATVKGAQVLMFGVGKPNQEFKMNTYEVYQKQLTIQGSFINPNAFEDS 292

Query: 323 IALLASGRVNVKPLITH 339
           +ALL+SG+++V  LI++
Sbjct: 293 LALLSSGKLDVLSLISN 309

gb|AAQ59327.1| L-threonine 3-dehydrogenase [Chromobacterium violaceum ATCC 12472]
ref|NP_901321.1| L-threonine 3-dehydrogenase [Chromobacterium violaceum ATCC 12472]
(341 aa)

Score: 146 bits (368), Expect: 1.03699e-33
Length: 336, Idn/Pos/Gap = 99/163/22 (29%/48%/6%)

Query:  37 LRSVPAPAPGEVRLQMRCV--GICGSDVHYW----WHGSCGPFRLHDPMIIGHESAGVVE  90
           +  VP P  G   L ++ V   ICG+D+H W    W     P     PM +GHE  GVV 
Sbjct:  15 MTDVPLPEVGHNDLLIKIVKTAICGTDIHIWNWDEWSQKTIPV----PMHVGHEYVGVVA  70

Query:  91 ALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPA 150
            +G+ V   ++G RV+ E  + C  C+ CR GR +LC N         +G+ A Y+  PA
Sbjct:  71 GMGSEVQGFKIGQRVSGEGHITCGYCRNCRAGRRHLCRNTTGVGVNR-EGAFAEYLVIPA 129

Query: 151 AWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGA 210
              + +P+ +S +  ++ +P   AVH    +   +G  VL+ GAGPIG++   +AK  GA
Sbjct: 130 FNAFPIPDDISDDLASIFDPFGNAVH-TALSFNLVGEDVLITGAGPIGIMAVAIAKHVGA 188

Query: 211 SIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLES 270
             +V+TD++D RL  A+      AV   R+    D   V+Q+       D+ L+ +G   
Sbjct: 189 RHVVITDVNDYRLELAKKMGATRAVNVARE----DLKAVMQELHMSEGFDVGLEMSGNPQ 244

Query: 271 TMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVF--RYSNTYPTCIALLAS 328
             R  +  +  GG++ L+G+  S   +       + ++I G++      T+   +AL+ S
Sbjct: 245 AFRQMLETMNHGGKVALLGIPPSNTAIDWNQVIFKGLEIKGIYGREMFETWYKMVALIQS 304

Query: 329 GRVNVKPLITHRFMGLEESSLEAAFETARTAANGAV 364
           G +++ P+ITH F   +    E  F    +  +G V
Sbjct: 305 G-LDISPIITHHF---KVDEFEQGFAAMLSGQSGKV 336

ref|NP_667423.1| threonine dehydrogenase [Yersinia pestis KIM]
gb|AAS60342.1| threonine 3-dehydrogenase [Yersinia pestis biovar Medievalis str. 91001]
ref|NP_991465.1| threonine 3-dehydrogenase [Yersinia pestis biovar Medievalis str. 91001]
emb|CAC88927.1| threonine 3-dehydrogenase [Yersinia pestis CO92]
gb|AAM83674.1| threonine dehydrogenase [Yersinia pestis KIM]
ref|NP_403726.1| threonine 3-dehydrogenase [Yersinia pestis CO92]
pir||AE0008 L-threonine 3-dehydrogenase (EC 1.1.1.103) [imported] - Yersinia pestis (strain CO92)
sp|Q8ZJN2|TDH_YERPE L-threonine 3-dehydrogenase
(341 aa)

Score: 146 bits (368), Expect: 1.07218e-33
Length: 340, Idn/Pos/Gap = 104/173/26 (30%/50%/7%)

Query:  35 VMLRSVPAPAPG--EVRLQMRCVGICGSDVHYW----WHGSCGPFRLHDPMIIGHESAGV  88
           + +  VP P  G  ++ +++R   ICG+DVH +    W     P     PM++GHE  G 
Sbjct:  13 IWMTDVPQPELGHNDIMIKIRKTAICGTDVHIYNWDEWSQKTIPV----PMVVGHEYVGE  68

Query:  89 VEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPN-IKFFATPPVDGSLARYVC 147
           V A+G  V    +GDRV+ E  + C  C+ CR GR +LC N +      P  GS A Y+ 
Sbjct:  69 VVAIGQEVKGFNIGDRVSGEGHITCGHCRNCRGGRTHLCRNTVGVGVNRP--GSFAEYLV 126

Query: 148 HPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKA 207
            PA   +++P+++S E  A+ +P   AVH    +   +G  VLV GAGPIG++   V K 
Sbjct: 127 IPAFNAFKIPDNISDELAAIFDPFGNAVH-TALSFDLVGEDVLVSGAGPIGIMAAAVCKH 185

Query: 208 FGASIIVVTDIDDRRLAFAETHAGADAV-INTRDLDEHDAALVVQQALDGAQADIALDCA 266
            GA  +V+ D+++ RL  A       AV ++  +L++    L + +       D+ L+ +
Sbjct: 186 VGARHVVIADVNEYRLDLARKMGVTRAVNVSKENLNDVMTELGMTEGF-----DVGLEMS 240

Query: 267 GLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVF--RYSNTYPTCIA 324
           G     R  ++ +  GGRI ++G+  S M +       + + I G++      T+    A
Sbjct: 241 GAPPAFRSLLNSMNHGGRIAMLGIPPSDMSIDWNQVIFKGLFIKGIYGREMFETWYKMAA 300

Query: 325 LLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAV 364
           L+ SG +++ P+ITHRF  ++E   +  F+  R+  +G V
Sbjct: 301 LIQSG-LDLTPIITHRF-PIDE--FQQGFDAMRSGKSGKV 336

ref|NP_756305.1| Threonine 3-dehydrogenase [Escherichia coli CFT073]
gb|AAN82879.1| Threonine 3-dehydrogenase [Escherichia coli CFT073]
sp|Q8FCA2|TDH_ECOL6 L-threonine 3-dehydrogenase
(341 aa)

Score: 146 bits (368), Expect: 1.13667e-33
Length: 340, Idn/Pos/Gap = 102/169/26 (30%/49%/7%)

Query:  35 VMLRSVPAPAPG--EVRLQMRCVGICGSDVHYW----WHGSCGPFRLHDPMIIGHESAGV  88
           + +  VP P  G  ++ +++R   ICG+DVH +    W     P     PM++GHE  G 
Sbjct:  13 IWMTDVPVPELGHNDLLIKIRKTAICGTDVHIYNWDEWSQKTIPV----PMVVGHEYVGE  68

Query:  89 VEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPN-IKFFATPPVDGSLARYVC 147
           V  +G  V   ++GDRV+ E  + C  C+ CR GR +LC N I      P  G  A Y+ 
Sbjct:  69 VVGIGQEVKGFKIGDRVSGEGHITCGHCRNCRGGRTHLCRNTIGVGVNRP--GCFAEYLV 126

Query: 148 HPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKA 207
            PA   +++P+++S +  ++ +P   AVH    +   +G  VLV GAGPIG++   VAK 
Sbjct: 127 IPAFNAFKIPDNISDDLASIFDPFGNAVH-TALSFDLVGEDVLVSGAGPIGIMAAAVAKH 185

Query: 208 FGASIIVVTDIDDRRLAFAETHAGADAV-INTRDLDEHDAALVVQQALDGAQADIALDCA 266
            GA  +V+TD+++ RL  A       AV +   +L++    L + +       D+ L+ +
Sbjct: 186 VGARNVVITDVNEYRLELARKMGITRAVNVAKENLNDVMTELGMTEGF-----DVGLEMS 240

Query: 267 GLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVF--RYSNTYPTCIA 324
           G     R  +  +  GGRI ++G+  S M +       + + I G++      T+    A
Sbjct: 241 GAPPAFRTMLDTMNHGGRIAMLGIPPSDMSIDWTKVIFKGLFIKGIYGREMFETWYKMAA 300

Query: 325 LLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAV 364
           L+ SG +++ P+ITHRF        +  F+  R+  +G V
Sbjct: 301 LIQSG-LDLSPIITHRF---SIDDFQKGFDAMRSGQSGKV 336

ref|YP_185129.1| sorbitol dehydrogenase [Staphylococcus aureus subsp. aureus COL]
gb|AAW38788.1| sorbitol dehydrogenase [Staphylococcus aureus subsp. aureus COL]
(351 aa)

Score: 145 bits (367), Expect: 1.42387e-33
Length: 351, Idn/Pos/Gap = 103/178/24 (29%/50%/6%)

Query:  27 LVRPRE----LRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIG  82
           LV+ RE    L ++ + V  P   +V++++   GICG+D+H +     G ++++ P+ +G
Sbjct:   4 LVKTREGHGNLELLDKEVATPLDDKVKIKVHYAGICGTDIHTYE----GHYKVNFPVTLG  59

Query:  83 HESAGVVEALGAGVTSLQVGDRVALEPGV-PCLQCQRCREGRYNLCPNIKFFATPPVDGS 141
           HE +G +  +GA V   +VGDRV  E     C +C+ C+   YNLC + K   T  VDG+
Sbjct:  60 HEFSGEIVEVGADVKDFKVGDRVTSETTFYVCNECEYCKSKDYNLCNHRKGIGTQ-VDGA 118

Query: 142 LARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLN 201
              YV       + +P+ VS +  AM EPL+ A H   +     G + +V+G GPIGLL 
Sbjct: 119 FTNYVIAREESLHHIPDEVSYQSAAMTEPLACAHHGVSKIQVNSGDVAVVMGPGPIGLLV 178

Query: 202 CMVAKAFGASIIVVTDIDDRRLAFAETHA-GADAVINTRDLDEHDAALVVQQALDGAQAD 260
             V K+ GA+ +VVT +D+ ++   +  A   D V+N   L + D    +    DG  AD
Sbjct: 179 AQVLKSKGAT-VVVTGLDNDKVRLDKAEALHMDYVVN---LQQTDLKTYINGITDGYGAD 234

Query: 261 IALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVP--LVDASSREIDIFGV-FRYSN 317
           + ++C+G     R  + ++R  G    +G+   A  +P  +     +EI + G   +   
Sbjct: 235 VVVECSGAVPAARQGLDILRKKGFYSQIGIFKDA-EIPFDMEKVIQKEITVVGSRSQKPA 293

Query: 318 TYPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVML 368
            +   + L+A G VN + L+T  +   + S  + A++  ++     +KV+L
Sbjct: 294 DWEPSLQLMADGLVNAEALVTKIY---DISKWDEAYQHLKSGE--GIKVLL 339

emb|CAG41995.1| putative zinc-binding dehydrogenase [Staphylococcus aureus subsp. aureus MSSA476]
dbj|BAB56412.1| sorbitol dehydrogenase homologue [Staphylococcus aureus subsp. aureus Mu50]
dbj|BAB94091.1| MW0226 [Staphylococcus aureus subsp. aureus MW2]
ref|NP_373486.1| hypothetical protein SA0240 [Staphylococcus aureus subsp. aureus N315]
dbj|BAB41464.1| SA0240 [Staphylococcus aureus subsp. aureus N315]
ref|YP_042349.1| putative zinc-binding dehydrogenase [Staphylococcus aureus subsp. aureus MSSA476]
ref|NP_645041.1| hypothetical protein MW0226 [Staphylococcus aureus subsp. aureus MW2]
pir||E89788 hypothetical protein SA0240 [imported] - Staphylococcus aureus (strain N315)
ref|NP_370774.1| sorbitol dehydrogenase homolog [Staphylococcus aureus subsp. aureus Mu50]
(347 aa)

Score: 145 bits (367), Expect: 1.42387e-33
Length: 333, Idn/Pos/Gap = 105/167/22 (31%/50%/6%)

Query:  47 EVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGDRVA 106
           +V +++R  GICGSD   +     GP+    P   GHE +GVV+A+G+ VT + VGD+V 
Sbjct:  27 DVIVKVRATGICGSDTSRY--KKMGPYIKGMPF--GHEFSGVVDAIGSDVTHVNVGDKVT  82

Query: 107 LEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPESVSLEEGA 166
             P +PC QC+ C +G Y  C  + F       GS A YV  PA    ++P++V   E A
Sbjct:  83 GCPAIPCYQCEYCLKGEYARCEKL-FVIGSYEPGSFAEYVKLPAQNVLKVPDNVDYIEAA 141

Query: 167 MCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFA 226
           M EP +V  H   ++    G  V V+G G IGLL    A+ FGA+ I+  DID  +L  A
Sbjct: 142 MVEPSAVVAHGFYKSNIQPGMTVAVMGCGSIGLLAIQWARIFGAAHIIAIDIDAHKLDIA 201

Query: 227 ETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVVRPGGRIC 286
            T  GA   IN++  +E+    +     +  Q D+A++ +G + T+   + + + GG + 
Sbjct: 202 -TSLGAHQTINSK--EENLEKFIENHYAN--QIDLAIESSGAKVTIGQILTLPKKGGEVV 256

Query: 287 LVGMGSSAMHVPLVDASS---REIDIFGVFR-YSNTYP-----TCIALLASGRVNVKPLI 337
           L+G+    + +  V        E+ + G +   S+ +P       +  + +  +NVKP+I
Sbjct: 257 LLGIPYDDIEIDRVHFEKILRNELTVCGSWNCLSSNFPGKEWTATLHYMKTKDINVKPII 316

Query: 338 THRFMGLEESSLEAAFETARTAANGAVKVMLTI 370
           +H F+ LE+      F+          KVM TI
Sbjct: 317 SH-FLPLEKGP--ETFDKLVNKKERFDKVMFTI 346

ref|YP_173941.1| Zn-dependent alcohol dehydrogenase [Bacillus clausii KSM-K16]
dbj|BAD62980.1| Zn-dependent alcohol dehydrogenase [Bacillus clausii KSM-K16]
(337 aa)

Score: 145 bits (367), Expect: 1.6003e-33
Length: 318, Idn/Pos/Gap = 98/155/15 (30%/48%/4%)

Query:  26 VLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHES  85
           V  RP   ++     P+  PGE  ++++ +GICG+D+H +      PF  + P ++GHE 
Sbjct:   5 VCERPNVFKMTKEKAPSIRPGEALVRIKRIGICGTDLHAYKGNQ--PFFSY-PRVLGHEL  61

Query:  86 AGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARY 145
           +GV+E +      LQ GDRVA+ P + C  C  CR G+ N C  +       +DG +   
Sbjct:  62 SGVIEEVEHNPEGLQAGDRVAIIPYLSCGNCHACRNGKTNCCTKVNVLGV-HIDGGMREL 120

Query: 146 VCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVA 205
           V  P     +   S+S +E A+ EPL++  HA  RA       VLV+GAGPIGL   + A
Sbjct: 121 VAVPTKQLMK-TTSLSYDEAALIEPLAIGAHAVNRAKPRRNEQVLVIGAGPIGLGVMLFA 179

Query: 206 KAFGASIIVVTDIDDRRLAFAETHAGADAVINTRD--LDEHDAALVVQQALDGAQADIAL 263
           K  GA +I + D+++ RL F +  A  DAV++  D  L E      +   L+     I  
Sbjct: 180 KEQGARVIAM-DVNEERLEFCQQWAKVDAVVHALDNPLSE------LNDRLNDELPTIVF 232

Query: 264 DCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNT-YPTC 322
           D  G   +M  A + V  GG++  VG+ +  +     +   RE+ +      +   +   
Sbjct: 233 DATGNNDSMTEAFNYVAHGGKLVYVGLVNGMIQFDDPEFHKREMTLMASRNATKEDFNYV 292

Query: 323 IALLASGRVNVKPLITHR 340
           I +L +G + +   ITHR
Sbjct: 293 IQVLETGSIQLDSYITHR 310

ref|YP_111486.1| putative zinc-containing alcohol dehydrogenase [Burkholderia pseudomallei K96243]
emb|CAH38951.1| putative zinc-containing alcohol dehydrogenase [Burkholderia pseudomallei K96243]
ref|YP_105484.1| oxidoreductase, zinc-binding dehydrogenase family [Burkholderia mallei ATCC 23344]
gb|AAU46941.1| oxidoreductase, zinc-binding dehydrogenase family [Burkholderia mallei ATCC 23344]
(343 aa)

Score: 145 bits (366), Expect: 1.78365e-33
Length: 344, Idn/Pos/Gap = 108/172/11 (31%/50%/3%)

Query:  26 VLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHES  85
           V+ +P  + V     P PA GEVR+++R  GICGSD+H + HG   PF +  P +IGHE 
Sbjct:   5 VVDQPHSMGVREMPTPEPAAGEVRVRVRYAGICGSDLHIF-HGK-NPF-VSYPRVIGHEF  61

Query:  86 AGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARY 145
            G +E++GAGV + ++G+ VA++P + C +C  C  GR N+C ++        DG  + Y
Sbjct:  62 VGRIESVGAGVDASRIGEIVAVDPVISCGRCHACAIGRRNVCRSLTVLGVHR-DGGFSEY 120

Query: 146 VCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVA 205
            C PAA  +R+   ++    A+ EP +VA +A  R G     + L+ GAG +GL    V 
Sbjct: 121 ACVPAANAHRIAPEIADTCAAIVEPFAVAANATARTGVLPSDVALIYGAGTVGLTLLQVL 180

Query: 206 KAFGASIIVVTDIDDRRLAFA-ETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALD 264
           K        + D  D RLA A +  A AD VI+       DA  + ++ +DG    I  D
Sbjct: 181 KHVYGIRAFIADRLDERLALARKCGAAADEVIHAATETVPDA--LERRGVDGGPTLI-FD 237

Query: 265 CAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIA 324
                S +  A+ +  P  RI ++G  S    +   + + +E+ +         +P  I 
Sbjct: 238 AVCHPSILEEAVRLAAPAARIGVLGFSSEPSSIVQAELTKKELTLCASRLNCAMFPQVIE 297

Query: 325 LLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVML 368
            +A GRV+ + ++TH    L+   +  AFE A      + K++L
Sbjct: 298 WIADGRVHPEHIVTHT---LDFRDVARAFELAERNPRESCKILL 338

ref|YP_152673.1| threonine 3-dehydrogenase [Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150]
gb|AAV79361.1| threonine 3-dehydrogenase [Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150]
ref|YP_218618.1| threonine 3-dehydrogenase [Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67]
gb|AAX67537.1| threonine 3-dehydrogenase [Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67]
gb|AAL22567.1| threonine 3-dehydrogenase [Salmonella typhimurium LT2]
ref|NP_462608.1| threonine 3-dehydrogenase [Salmonella typhimurium LT2]
sp|Q8ZL52|TDH_SALTY L-threonine 3-dehydrogenase
(341 aa)

Score: 145 bits (366), Expect: 1.78365e-33
Length: 339, Idn/Pos/Gap = 101/167/24 (29%/49%/7%)

Query:  35 VMLRSVPAPAPG--EVRLQMRCVGICGSDVHYW----WHGSCGPFRLHDPMIIGHESAGV  88
           + +  VP P  G  ++ +++R   ICG+DVH +    W     P     PM++GHE  G 
Sbjct:  13 IWMTDVPEPEVGHNDLLIKIRKTAICGTDVHIYNWDDWSQKTIPV----PMVVGHEYVGE  68

Query:  89 VEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCH 148
           V  +G  V   ++GDRV+ E  + C  C+ CR GR +LC N          G  A Y+  
Sbjct:  69 VVGIGQEVKGFKIGDRVSGEGHITCGHCRNCRGGRTHLCRNTTGVGVNR-PGCFAEYLVI 127

Query: 149 PAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAF 208
           PA   +++P+++S +  ++ +P   AVH    +   +G  VLV GAGPIG++   VAK  
Sbjct: 128 PAFNAFKIPDNISDDLASIFDPFGNAVH-TALSFDLVGEDVLVSGAGPIGVMAAAVAKHV 186

Query: 209 GASIIVVTDIDDRRLAFAETHAGADAV-INTRDLDEHDAALVVQQALDGAQADIALDCAG 267
           GA  +V+TD+++ RL  A       AV +    L++  A L + +       D+ L+ +G
Sbjct: 187 GARHVVITDVNEYRLELARKMGVTRAVNVAKESLNDVMAELGMTEGF-----DVGLEMSG 241

Query: 268 LESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVF--RYSNTYPTCIAL 325
                R  +  +  GGRI ++G+  S M +       + + I G++      T+    AL
Sbjct: 242 APPAFRTMLDTMNHGGRIAMLGIPPSDMSIDWTKVIFKGLFIKGIYGREMFETWYKMAAL 301

Query: 326 LASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAV 364
           + SG +++ P+ITHRF        +  F+  R+  +G V
Sbjct: 302 IQSG-LDLSPIITHRF---SIDDFQKGFDAMRSGQSGKV 336

ref|ZP_00378454.1| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Brevibacterium linens BL2]
(353 aa)

Score: 145 bits (366), Expect: 1.79859e-33
Length: 323, Idn/Pos/Gap = 101/163/17 (31%/50%/5%)

Query:  35 VMLRSVPAP--APGEVRLQMRCVGICGSDVHYWWHGSCG-PFRLHD--------PMIIGH  83
           + +  +P P   PG V + +   GICG+D+H +  G    P   H         P+ +GH
Sbjct:  12 IRIEDIPEPELKPGTVAIDVAWCGICGTDLHEYLEGPIFVPPEGHPHPISGESAPVTMGH  71

Query:  84 ESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLA 143
           E +G + +LG GV+ L+VG  V +EP +            Y L  ++ F       G L+
Sbjct:  72 EFSGTITSLGEGVSDLEVGQNVVVEPYIIGDDVDTSIGQSYQLSQDMNFIGLGGGGGGLS 131

Query: 144 RYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCM 203
             +     W + + E + L++ A+ EPLSVA HA  R+G   G + +V GAGPIGLL   
Sbjct: 132 EKIVVQRRWVHPIGE-IPLDQAALIEPLSVAHHAVVRSGAKSGQVAIVGGAGPIGLLTAA 190

Query: 204 VAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIAL 263
           V KA G ++ + +++ + R   A +   AD V++ R   E D A  V+Q  +G  AD+  
Sbjct: 191 VLKAEGLTVFI-SELSEARKKMALSTGVADEVLDPR---EGDVAETVRQRTNGQGADVGF 246

Query: 264 DCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCI 323
           +C+ +   + + +  VRPG  I  V +      V +     +EID+ G   YS  +P+ I
Sbjct: 247 ECSSVPVVLDMLLDAVRPGAVIVNVSIWGHKPEVDMPKLVLKEIDLRGTIGYSGDHPSTI 306

Query: 324 ALLASGRVNVKPLITHRFMGLEE 346
            L+ SG++++   IT R +GL+E
Sbjct: 307 ELVRSGKIDLSSFITGR-IGLDE 328

ref|NP_754504.1| Galactitol-1-phosphate 5-dehydrogenase [Escherichia coli CFT073]
gb|AAN81072.1| Galactitol-1-phosphate 5-dehydrogenase [Escherichia coli CFT073]
(346 aa)

Score: 145 bits (366), Expect: 1.92275e-33
Length: 345, Idn/Pos/Gap = 111/171/45 (32%/49%/13%)

Query:  47 EVRLQMRCVGICGSDV--------HYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTS  98
           EVR+++   G+CGSD+        HY+            P+ +GHE +G ++A+G+GV  
Sbjct:  27 EVRVKIASSGLCGSDLPRIFKNGAHYY------------PITLGHEFSGYIDAVGSGVDD  74

Query:  99 LQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPE 158
           L  GD VA  P +PC  C  C +G Y+ C    F  +   DG  A Y+       + LP 
Sbjct:  75 LHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRR-DGGFAEYIVVKRNNVFALPA 133

Query: 159 SVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDI 218
            + +E+GA  EP++V +HA   A       V+++GAG IGLL    A A GA  +   DI
Sbjct: 134 DMPIEDGAFIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDI 193

Query: 219 DDRRLAFAETHAGADAVINTRDLDEHDAALVVQQAL-DGAQADIALDCAGLESTMRLAMH 277
              +LA A++  GA    N+R++    +A  +Q  L D     + L+ AG+  T+ LA+ 
Sbjct: 194 SSEKLALAKSF-GAMQTFNSREM----SAPQIQGVLRDLRFNQLILETAGVPQTVELAVE 248

Query: 278 VVRPGGRICLVGMGSSAMHVPLVDAS-----SREIDIFGVF-RYSNTYP-----TCIALL 326
           +  P  ++ LVG     +H  L  A+      +E+ + G +  YS+ +P     T   LL
Sbjct: 249 IAGPHAQLALVGTLHQDLH--LTSATFGKILRKELTVIGSWMNYSSPWPGQEWETASRLL 306

Query: 327 ASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLTIP 371
              +++++PLI HR  G  ES  +A  + AR A  G V   L IP
Sbjct: 307 TERKLSLEPLIAHR--GSFESFAQAVRDIARNAMPGKV---LLIP 346

dbj|BAB56410.1| sorbitol dehydrogenase [Staphylococcus aureus subsp. aureus Mu50]
ref|NP_373484.1| sorbitol dehydrogenase [Staphylococcus aureus subsp. aureus N315]
dbj|BAB41462.1| sorbitol dehydrogenase [Staphylococcus aureus subsp. aureus N315]
pir||C89788 sorbitol dehydrogenase [imported] - Staphylococcus aureus  (strain N315)
ref|NP_370772.1| sorbitol dehydrogenase [Staphylococcus aureus subsp. aureus Mu50]
(351 aa)

Score: 145 bits (365), Expect: 2.42876e-33
Length: 321, Idn/Pos/Gap = 98/163/19 (30%/50%/5%)

Query:  27 LVRPRE----LRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIG  82
           LV+ RE    L ++ + V  P   +V++++   GICG+D+H +     G ++++ P+ +G
Sbjct:   4 LVKTREGHGNLELLDKEVATPLDDKVKIKVHYAGICGTDIHTYE----GHYKVNFPVTLG  59

Query:  83 HESAGVVEALGAGVTSLQVGDRVALEPGV-PCLQCQRCREGRYNLCPNIKFFATPPVDGS 141
           HE +G +  +GA V   +VGDRV  E     C +C+ C+   YNLC + K   T  VDG 
Sbjct:  60 HEFSGEIVEVGADVKDFKVGDRVTSETTFYVCNECEYCKSKDYNLCNHRKGIGTQ-VDGV 118

Query: 142 LARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLN 201
              YV       + +P+ VS +  AM EPL+ A H   +     G + +V+G GPIGLL 
Sbjct: 119 FTNYVIAREESLHHIPDEVSYQSAAMTEPLACAHHGVSKIQVNSGDVAVVMGPGPIGLLV 178

Query: 202 CMVAKAFGASIIVVTDIDDRRLAFAETHA-GADAVINTRDLDEHDAALVVQQALDGAQAD 260
             V K+ GA+ +VVT +D+ ++   +  A   D V+N   L + D    +    DG  AD
Sbjct: 179 AQVLKSKGAT-VVVTGLDNDKVRLDKAEALHMDYVVN---LQQTDLKTYINGITDGYGAD 234

Query: 261 IALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVP--LVDASSREIDIFGV-FRYSN 317
           + ++C+G     R  + ++R  G    +G+   A  +P  +     +EI + G   +   
Sbjct: 235 VVVECSGAVPAARQGLDIIRKKGFYSQIGIFKDA-EIPFDMEKVIQKEITVVGSRSQKPA 293

Query: 318 TYPTCIALLASGRVNVKPLIT 338
            +   + L+A G VN + L+T
Sbjct: 294 DWEPSLQLMADGLVNAEALVT 314

emb|CAG41993.1| putative zinc-binding dehydrogenase [Staphylococcus aureus subsp. aureus MSSA476]
dbj|BAB94089.1| sorbitol dehydrogenase [Staphylococcus aureus subsp. aureus MW2]
ref|YP_042347.1| putative zinc-binding dehydrogenase [Staphylococcus aureus subsp. aureus MSSA476]
ref|NP_645039.1| sorbitol dehydrogenase [Staphylococcus aureus subsp. aureus MW2]
(351 aa)

Score: 145 bits (365), Expect: 2.46963e-33
Length: 321, Idn/Pos/Gap = 98/164/19 (30%/51%/5%)

Query:  27 LVRPRE----LRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIG  82
           LV+ RE    L ++ + V  P   +V++++   GICG+D+H +     G ++++ P+ +G
Sbjct:   4 LVKTREGHGNLELLDKEVATPLDDKVKIKVHYAGICGTDIHTYE----GHYKVNFPVTLG  59

Query:  83 HESAGVVEALGAGVTSLQVGDRVALEPGV-PCLQCQRCREGRYNLCPNIKFFATPPVDGS 141
           HE +G +  +GA V   +VGDRV  E     C +C+ C+   YNLC + K   T  VDG+
Sbjct:  60 HEFSGEIVEVGADVKDFKVGDRVTSETTFYVCNECEYCKSKDYNLCNHRKGIGTQ-VDGA 118

Query: 142 LARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLN 201
              YV       + +P+ VS +  AM EPL+ A H   +     G + +V+G GPIGLL 
Sbjct: 119 FTNYVIAREESLHHIPDEVSYQSAAMTEPLACAHHGVSKIQVNSGDVAVVMGPGPIGLLV 178

Query: 202 CMVAKAFGASIIVVTDIDDRRLAFAETHA-GADAVINTRDLDEHDAALVVQQALDGAQAD 260
             V K+ GA+ +VVT +D+ ++   +  A   D V+N   L + D    +    DG  AD
Sbjct: 179 AQVLKSKGAT-VVVTGLDNDKVRLDKAEALHMDYVVN---LQQTDLKTYINGITDGYGAD 234

Query: 261 IALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVP--LVDASSREIDIFGV-FRYSN 317
           + ++C+G     R  + ++R  G    +G+   A  +P  +     +EI + G   +   
Sbjct: 235 VVVECSGAVPAARQGLDILRKKGFYSQIGIFKDA-EIPFDMEKVIQKEITVVGSRSQKPA 293

Query: 318 TYPTCIALLASGRVNVKPLIT 338
            +   + L+A G VN + L+T
Sbjct: 294 DWEPSLQLMADGLVNAEALVT 314

ref|NP_693672.1| sorbitol dehydrogenase [Oceanobacillus iheyensis HTE831]
dbj|BAC14706.1| sorbitol dehydrogenase (L-iditol 2-dehydrogenase) [Oceanobacillus iheyensis HTE831]
(349 aa)

Score: 144 bits (364), Expect: 2.91813e-33
Length: 347, Idn/Pos/Gap = 112/168/28 (32%/48%/8%)

Query:  37 LRSVPAPAP-----GEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEA  91
           LR    P P      +V ++++ VGICGSD   +     GP+   + M  GHE AG V  
Sbjct:  12 LRYEDTPKPMIEKDDDVIIKVKSVGICGSDTSRY--KKLGPYV--EGMTFGHEFAGEVIE  67

Query:  92 LGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFF-ATPPVDGSLARYVCHPA 150
           +G  VT+ + GDRV   P   C  C  CREG    C  +    A  P  G+ A Y   P 
Sbjct:  68 VGKSVTNFKSGDRVVACPTFSCGNCHYCREGHPTRCVELTVIGARNP--GAYAEYTKLPE 125

Query: 151 AWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGA 210
                LP+S+  +  A+ EP +V  H   RA  T GS V ++G G IGLL    AK FGA
Sbjct: 126 GHVKILPDSIDDDTAALVEPSAVVAHGFYRASITPGSSVAIMGVGSIGLLAVQWAKIFGA 185

Query: 211 SIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLES 270
           S ++  DIDD +L  A+   GAD V+N     + +A  +V+Q  D    D+A++ AG   
Sbjct: 186 SKVIAIDIDDHKLKIAQ-ELGADIVVNPM---KENAEGIVKQHTDELGVDLAVESAGSPI 241

Query: 271 TMRLAMHVVRPGGRICLVGM--GSSAMHVPLVDASSR-EIDIFGVFR-YSNTYP-----T 321
           T    + + + GG +  +G+  G   +     +   R E+ I G +   S  +P      
Sbjct: 242 TSEQVLALPKKGGEVVFLGIPYGDITLKRYYFEKIVRNELRILGSWNALSAPFPGKEWNA 301

Query: 322 CIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVML 368
            +  +++G++N+KP+I+HR +GL+       F       + AVKV+ 
Sbjct: 302 TLHYMSTGQLNIKPMISHR-LGLQAGP--EIFHQITNKLSDAVKVIF 345

emb|CAB84091.1| putative zinc-binding alcohol dehydrogenase [Neisseria meningitidis Z2491]
ref|NP_283604.1| zinc-binding alcohol dehydrogenase [Neisseria meningitidis Z2491]
pir||H81925 probable alcohol dehydrogenase (EC 1.1.1.-) NMA0808 [similarity] - Neisseria meningitidis (strain Z2491 serogroup A)
(354 aa)

Score: 144 bits (364), Expect: 3.17206e-33
Length: 346, Idn/Pos/Gap = 103/168/17 (29%/48%/4%)

Query:  35 VMLRSVPAP--APGEVRLQMRCVGICGSDVHYWWHGS-----CG-PFRLHD---PMIIGH  83
           + +  +P P  APG V + +   GICG+D+H +  G      CG P  +     P+ +GH
Sbjct:  12 IRIEDIPEPTVAPGTVGINVAWCGICGTDLHEFMEGPIFIPPCGHPHPISGESAPVTMGH  71

Query:  84 ESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLA 143
           E +GVV A+G GV  ++VG  V +EP +            Y+L  ++ F       G L+
Sbjct:  72 EFSGVVYAVGEGVDDIKVGQHVVVEPYIIHDDVPTGEGSNYHLSKDMNFIGLGGCGGGLS 131

Query: 144 RYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCM 203
             +     W + + + + L++ A+ EPLSV  HA  R+G   G + LV GAGPIGLL   
Sbjct: 132 EKIAVKRRWVHPISDKIPLDQAALIEPLSVGHHAYVRSGAKAGDVALVGGAGPIGLLLAA 191

Query: 204 VAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIAL 263
           V KA G  +I +T++   R   A     AD ++   D  E D    V++  +G   D+A 
Sbjct: 192 VLKAKGIKVI-ITELSKARKDKARESGVADYIL---DPSEVDVVEEVKKLTNGEGVDVAF 247

Query: 264 DCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCI 323
           +C  +   +   +   +P   + +V + S    V +     +E+D+ G   Y N +   I
Sbjct: 248 ECTSVNKVLDTLVEACKPAANLVIVSIWSHPATVNVHSVVMKELDVRGTIAYCNDHAETI 307

Query: 324 ALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLT 369
            L+  G++N++P IT R + L+E   E  FE        AVK++++
Sbjct: 308 KLVEEGKINLEPFITQR-IKLDELVSE-GFERLIHNNESAVKIIVS 351

gb|AAG58763.1| threonine dehydrogenase [Escherichia coli O157:H7 EDL933]
sp|Q8XEJ1|TDH_ECO57 L-threonine 3-dehydrogenase
pir||G86037 threonine dehydrogenase [imported] - Escherichia coli  (strain O157:H7, substrain EDL933)
ref|NP_290199.1| threonine dehydrogenase [Escherichia coli O157:H7 EDL933]
(341 aa)

Score: 144 bits (364), Expect: 3.44808e-33
Length: 317, Idn/Pos/Gap = 99/162/23 (31%/51%/7%)

Query:  35 VMLRSVPAPAPG--EVRLQMRCVGICGSDVHYW----WHGSCGPFRLHDPMIIGHESAGV  88
           + +  VP P  G  ++ +++R   ICG+DVH +    W     P     PM++GHE  G 
Sbjct:  13 IWMTDVPVPELGHNDLLIKIRKTAICGTDVHIYNWDEWSQKTIPV----PMVVGHEYVGE  68

Query:  89 VEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPN-IKFFATPPVDGSLARYVC 147
           V  +G  V   ++GDRV+ E  + C  C+ CR GR +LC N I      P  G  A Y+ 
Sbjct:  69 VVGIGQEVKGFKIGDRVSGEGHITCGHCRNCRGGRTHLCRNTIGVGVNRP--GCFAEYLV 126

Query: 148 HPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKA 207
            PA   +++P+++S +  ++ +P   AVH    +   +G  VLV GAGPIG++   VAK 
Sbjct: 127 IPAFNAFKIPDNISDDLASIFDPFGNAVH-TALSFDLVGEDVLVSGAGPIGIMAAAVAKH 185

Query: 208 FGASIIVVTDIDDRRLAFAETHAGADAV-INTRDLDEHDAALVVQQALDGAQADIALDCA 266
            GA  +V+TD+++ RL  A       AV +   +L++  A L + +       D+ L+ +
Sbjct: 186 VGARNVVITDVNEYRLELARKMGITRAVNVAKENLNDVMAELGMTEGF-----DVGLEMS 240

Query: 267 GLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVF--RYSNTYPTCIA 324
           G     R  +  +  GGRI ++G+  S M +       + + I G++      T+    A
Sbjct: 241 GAPPAFRTMLDTMNHGGRIAMLGIPPSDMSIDWTKVIFKGLFIKGIYGREMFETWYKMAA 300

Query: 325 LLASGRVNVKPLITHRF 341
           L+ SG +++ P+ITHRF
Sbjct: 301 LIQSG-LDLSPIITHRF 316

dbj|BAB37917.1| threonine dehydrogenase [Escherichia coli O157:H7]
ref|NP_312521.1| threonine dehydrogenase [Escherichia coli O157:H7]
pir||F91190 threonine dehydrogenase [imported] - Escherichia coli  (strain O157:H7, substrain RIMD 0509952)
(341 aa)

Score: 144 bits (363), Expect: 3.65547e-33
Length: 313, Idn/Pos/Gap = 97/161/15 (30%/51%/4%)

Query:  35 VMLRSVPAPAPG--EVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEAL  92
           + +  VP P  G  ++ +++R   ICG+DVH +         +  PM++GHE  G V  +
Sbjct:  13 IWMTDVPVPELGHNDLLIKIRKTAICGTDVHIYNWDEWSQKNIPVPMVVGHEYVGEVVGI  72

Query:  93 GAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPN-IKFFATPPVDGSLARYVCHPAA 151
           G  V   ++GDRV+ E  + C  C+ CR GR +LC N I      P  G  A Y+  PA 
Sbjct:  73 GQEVKGFKIGDRVSGEGHITCGHCRNCRGGRTHLCRNTIGVGVNRP--GCFAEYLVIPAF 130

Query: 152 WCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGAS 211
             +++P+++S +  ++ +P   AVH    +   +G  VLV GAGPIG++   VAK  GA 
Sbjct: 131 NAFKIPDNISDDLASIFDPFGNAVH-TALSFDLVGEDVLVSGAGPIGIMAAAVAKHVGAR 189

Query: 212 IIVVTDIDDRRLAFAETHAGADAV-INTRDLDEHDAALVVQQALDGAQADIALDCAGLES 270
            +V+TD+++ RL  A       AV +   +L++  A L + +       D+ L+ +G   
Sbjct: 190 NVVITDVNEYRLELARKMGITRAVNVAKENLNDVMAELGMTEGF-----DVGLEMSGAPP 244

Query: 271 TMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVF--RYSNTYPTCIALLAS 328
             R  +  +  GGRI ++G+  S M +       + + I G++      T+    AL+ S
Sbjct: 245 AFRTMLDTMNHGGRIAMLGIPPSDMSIDWTKVIFKGLFIKGIYGREMFETWYKMAALIQS 304

Query: 329 GRVNVKPLITHRF 341
           G +++ P+ITHRF
Sbjct: 305 G-LDLSPIITHRF 316

ref|NP_707977.1| galactitol-1-phosphate dehydrogenase [Shigella flexneri 2a str. 301]
gb|AAN43684.1| galactitol-1-phosphate dehydrogenase [Shigella flexneri 2a str. 301]
ref|NP_837701.1| galactitol-1-phosphate dehydrogenase [Shigella flexneri 2a str. 2457T]
gb|AAP17510.1| galactitol-1-phosphate dehydrogenase [Shigella flexneri 2a str. 2457T]
(346 aa)

Score: 144 bits (363), Expect: 3.8112e-33
Length: 344, Idn/Pos/Gap = 109/170/43 (31%/49%/12%)

Query:  47 EVRLQMRCVGICGSDV--------HYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTS  98
           EVR+++   G+CGSD+        HY+            P+ +GHE +G ++A+G+GV  
Sbjct:  27 EVRVKIASSGLCGSDLPRIFKNGAHYY------------PITLGHEFSGYIDAVGSGVDD  74

Query:  99 LQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPE 158
           L  GD VA  P +PC  C  C +G Y+ C    F  +   DG  A Y+       + LP 
Sbjct:  75 LHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRR-DGGFAEYIVVKRKNVFALPT 133

Query: 159 SVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDI 218
            + +E+GA  EP++V +HA   A       V+++GAG IGLL    A A GA  +   DI
Sbjct: 134 DMPIEDGAFIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDI 193

Query: 219 DDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHV 278
              +LA A++  GA    N+ ++       V+++ L   Q  + L+ AG+  T+ LA+ +
Sbjct: 194 SSEKLALAKSF-GAMQTFNSSEMSAPQMQSVLRE-LRFNQ--LILETAGVPQTVELAVEI 249

Query: 279 VRPGGRICLVGMGSSAMHVPLVDAS-----SREIDIFGVF-RYSNTYP-----TCIALLA 327
             P  ++ LVG     +H  L  A+      +E+ + G +  YS+ +P     T   LL 
Sbjct: 250 AGPHAQLALVGTLHQDLH--LTSATFGKILRKELTVIGSWMNYSSPWPGQEWETASRLLT 307

Query: 328 SGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLTIP 371
             +++++PLI HR  G  ES  +A  + AR A  G V   L IP
Sbjct: 308 ERKLSLEPLIAHR--GSFESFTQAVRDIARNAMQGKV---LLIP 346

ref|YP_039706.1| putative zinc-binding dehydrogenase [Staphylococcus aureus subsp. aureus MRSA252]
emb|CAG39269.1| putative zinc-binding dehydrogenase [Staphylococcus aureus subsp. aureus MRSA252]
(351 aa)

Score: 144 bits (363), Expect: 4.24784e-33
Length: 320, Idn/Pos/Gap = 97/162/17 (30%/50%/5%)

Query:  27 LVRPRE----LRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIG  82
           LV+ RE    L ++ + V  P   +V++++   GICG+D+H +     G ++++ P+ +G
Sbjct:   4 LVKTREGHGNLELLDKEVATPLDDKVKIKVHYAGICGTDIHTYE----GHYKVNFPVTLG  59

Query:  83 HESAGVVEALGAGVTSLQVGDRVALEPGV-PCLQCQRCREGRYNLCPNIKFFATPPVDGS 141
           HE +G +  +GA V   +VGDRV  E     C +C+ C    YNLC + K   T  VDG+
Sbjct:  60 HEFSGEIVEVGADVKDFKVGDRVTSETTFYVCNECEYCESKDYNLCNHRKGIGTQ-VDGA 118

Query: 142 LARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLN 201
              YV       + +P+ VS +  AM EPL+ A H   +     G + +V+G GPIGLL 
Sbjct: 119 FTNYVIAREESLHHIPDEVSYQSAAMTEPLACAHHGVSKIQVNSGDVAVVMGPGPIGLLV 178

Query: 202 CMVAKAFGASIIVVTDIDDRRLAFAETHA-GADAVINTRDLDEHDAALVVQQALDGAQAD 260
             V K+ GA+ +VVT +D+ ++   +  A   D V+N   L + D    +    DG  AD
Sbjct: 179 AQVLKSKGAT-VVVTGLDNDKVRLDKAEALHMDYVVN---LQQTDLKTYINGITDGYGAD 234

Query: 261 IALDCAGLESTMRLAMHVVRPGGRICLVGMGSSA-MHVPLVDASSREIDIFGV-FRYSNT 318
           + ++C+G     R  + ++R  G    +G+   A +   +     +EI + G   +    
Sbjct: 235 VVVECSGAVPAARQGLDILRKKGFYSQIGIFKDAEITFDMEKVIQKEITVVGSRSQKPAD 294

Query: 319 YPTCIALLASGRVNVKPLIT 338
           +   + L+A G VN + L+T
Sbjct: 295 WEPSLQLMADGLVNAEALVT 314

gb|AAL20461.1| putative zinc-binding dehydrogenase [Salmonella typhimurium LT2]
ref|NP_460502.1| putative zinc-binding dehydrogenase [Salmonella typhimurium LT2]
(341 aa)

Score: 144 bits (362), Expect: 6.08114e-33
Length: 324, Idn/Pos/Gap = 95/164/21 (29%/50%/6%)

Query:  29 RPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPM-----IIGH  83
           +P E+       P     EV +++   GICGSD+        G FR  +P+     IIGH
Sbjct:  10 KPGEVETRWVDYPHKKENEVLIKVDAAGICGSDI--------GAFRGTNPLVTYPRIIGH  61

Query:  84 ESAGVVEALGAGVT-SLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSL 142
           E  G+V   GAG+  +++ GDRV ++P + C  C  C  GR N C N+       VDG++
Sbjct:  62 EVTGIVLQEGAGMPDNIKEGDRVIVDPYIYCGHCYPCSVGRTNCCENLNVIGVH-VDGAM 120

Query: 143 ARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNC 202
              V HPA   +++P++V  E   + EPL++A+HA  RA    G  V ++GAG IGL+  
Sbjct: 121 QEVVTHPAHLIHKIPDNVPSEMAPLAEPLTIALHALHRANVKAGEYVAIIGAGAIGLMAA 180

Query: 203 MVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIA 262
           + A+ + A+ I++ DI + RL +A+   G   V+N  D    DA   ++    G  A + 
Sbjct: 181 LSARHYKATPILI-DIVEERLRYAQK-LGVPYVLNAADDQVIDA---IKNITHGTMAQVV 235

Query: 263 LDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTC 322
           ++ +G  S +R  + +    GRI   G       +P    + +E+D+ G    +  +   
Sbjct: 236 IEASGANSAIRNTLDLASFAGRISFTGWPKQETSLPTNLITYKELDLRGSRTSAGEFDEA 295

Query: 323 IALLASGRVNVKPLITHRFMGLEE 346
           + +L++  +N + +++ + + L+E
Sbjct: 296 LRMLSTLEINPQDVVS-KVVNLDE 318

emb|CAC46894.1| PROBABLE THREONINE 3-DEHYDROGENASE PROTEIN [Sinorhizobium meliloti]
ref|NP_386421.1| PROBABLE THREONINE 3-DEHYDROGENASE PROTEIN [Sinorhizobium meliloti 1021]
sp|Q52998|TDH_RHIME L-threonine 3-dehydrogenase
(344 aa)

Score: 144 bits (362), Expect: 6.18347e-33
Length: 338, Idn/Pos/Gap = 104/168/16 (30%/49%/4%)

Query:  32 ELRVMLRSVPAP--APGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVV  89
           E+ + +  VP P   P +V +++R   ICG+DVH W         +  PM++GHE  G V
Sbjct:  14 EVGLWMERVPVPEIGPNDVLIRVRKSAICGTDVHIWNWDQWAEKTIPVPMVVGHEFMGEV  73

Query:  90 EALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPN-IKFFATPPVDGSLARYVCH 148
             +G  V+   VG+RV+ E  + C +C+ CR GR +LC N +      P  GS A +VC 
Sbjct:  74 VEVGPAVSKHHVGERVSGEGHIVCGKCRNCRAGRGHLCRNTLGVGVNRP--GSFAEFVCL 131

Query: 149 PAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAF 208
           P      +P+ V  E  A+ +P   AVH    +   +G  VLV GAGPIG++  MVAK  
Sbjct: 132 PEYNVVSIPDDVPDEIAAIFDPFGNAVH-TALSFDLVGEDVLVTGAGPIGIMGAMVAKRC 190

Query: 209 GASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGL 268
           GA  +V+TDI+  RL  A    G D V++       D   V+         D+ L+ +G 
Sbjct: 191 GARKVVITDINPVRLDLARK-LGIDHVVDASKEKLADVMRVIGMT---EGFDVGLEMSGA 246

Query: 269 ESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVF--RYSNTYPTCIALL 326
               R  +  +  GG+I ++G+  +   +       + +++ G++      T+   IA +
Sbjct: 247 APAFRDMIDKMNNGGKIAILGIAPAGFEIDWNKVIFKMLNLKGIYGREMFETWYKMIAFV 306

Query: 327 ASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAV 364
             G +++ P+ITHR +G+++      FE  R+  +G V
Sbjct: 307 QGG-LDLSPIITHR-IGIDD--FRDGFEAMRSGNSGKV 340

gb|AAF41031.1| alcohol dehydrogenase, zinc-containing [Neisseria meningitidis MC58]
pir||E81178 probable alcohol dehydrogenase (EC 1.1.1.-) NMB0604 [similarity] - Neisseria meningitidis (strain MC58 serogroup B)
ref|NP_273648.1| alcohol dehydrogenase, zinc-containing [Neisseria meningitidis MC58]
(354 aa)

Score: 143 bits (361), Expect: 6.39333e-33
Length: 346, Idn/Pos/Gap = 101/168/17 (29%/48%/4%)

Query:  35 VMLRSVPAP--APGEVRLQMRCVGICGSDVHYWWHGS-----CG-PFRLHD---PMIIGH  83
           + +  +P P  APG V + +   GICG+D+H +  G      CG P  +     P+ +GH
Sbjct:  12 IRIEDIPEPTVAPGTVGINVAWCGICGTDLHEFMEGPIFIPPCGHPHPISGESAPVTMGH  71

Query:  84 ESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLA 143
           E +GVV A+G GV  ++VG  V +EP +            Y+L  ++ F       G L+
Sbjct:  72 EFSGVVYAVGEGVDDIKVGQHVVVEPYIIRDDVPTGEGSNYHLSKDMNFIGLGGCGGGLS 131

Query: 144 RYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCM 203
             +     W + + + + L++ A+ EPLSV  HA  R+G   G + LV GAGPIGLL   
Sbjct: 132 EKIAVKRRWVHPISDKIPLDQAALIEPLSVGHHAYVRSGAKEGDVALVGGAGPIGLLLAA 191

Query: 204 VAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIAL 263
           V KA G  +I +T++   R   A     AD ++   D  E D    V++  +G   D+A 
Sbjct: 192 VLKAKGIKVI-ITELSKARKDKARESGVADYIL---DPSEVDVVAEVKKLTNGEGVDVAF 247

Query: 264 DCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCI 323
           +C  +   +   +   +P   + +V + S    + +     +E+D+ G   Y N +   I
Sbjct: 248 ECTSVNKVLDTLVEACKPAANLVIVSIWSHPATINVHSVVMKELDVRGTIAYCNDHAETI 307

Query: 324 ALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLT 369
            L+  G++N++P IT R + L+E  +   FE        AVK++++
Sbjct: 308 KLVEEGKINLEPFITQR-IKLDE-LVSKGFERLIHNNESAVKIIVS 351

ref|NP_438226.1| zinc-type alcohol dehydrogenase [Haemophilus influenzae Rd KW20]
gb|AAC21731.1| zinc-type alcohol dehydrogenase [Haemophilus influenzae Rd KW20]
pir||F64141 probable L-iditol 2-dehydrogenase (EC 1.1.1.14) HI0053 - Haemophilus influenzae (strain Rd KW20)
sp|Q57517|Y053_HAEIN Hypothetical zinc-type alcohol dehydrogenase-like protein HI0053
(342 aa)

Score: 143 bits (361), Expect: 6.39333e-33
Length: 312, Idn/Pos/Gap = 89/168/22 (28%/53%/7%)

Query:  35 VMLRSVPAP--APGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPM-----IIGHESAG  87
           V+++ VP P  +  +V +Q+  +GICGSD+        G +R  +P+     I+GHE  G
Sbjct:  16 VVVKEVPYPEKSDNDVLIQVESMGICGSDI--------GAYRGTNPLVTYPRILGHEIVG  67

Query:  88 VVEALGAGVTS-LQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYV 146
            V   G G++  ++VGDRV ++P V C QC  C  GR N C ++K      +DG +   +
Sbjct:  68 RVIESGIGMSDGVRVGDRVIVDPYVCCGQCYPCSIGRTNCCESLKVIGV-HIDGGMQEVI 126

Query: 147 CHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAK 206
            HPA    ++P+++ + +  + EPL++A+HA  R     G  ++++GAG IGL+  + A 
Sbjct: 127 RHPAHLLTKVPDNLPIHQLPLAEPLTIALHALHRTTLKSGEHIVIIGAGAIGLMAALAAV 186

Query: 207 AFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCA 266
            +GA I ++ DI ++RL +A++  G + ++N     + D    +++   G  A++ ++ +
Sbjct: 187 QYGA-IPILVDILEQRLEYAKS-LGIEHIVNPH---KEDDIKRIKEITSGRMAEVVMEAS 241

Query: 267 GLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALL 326
           G   +++  +H     GRI L G   +   +P    + +E++I+G       +   + +L
Sbjct: 242 GANISIKNTLHYASFAGRIALTGWPKTETPLPTNLITFKELNIYGSRTSKGEFEEALDML 301

Query: 327 ASGRVNVKPLIT 338
           A+ ++N   +IT
Sbjct: 302 ATNKINASHIIT 313

ref|ZP_00157560.2| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Haemophilus influenzae R2866]
ref|ZP_00154783.2| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Haemophilus influenzae R2846]
(342 aa)

Score: 143 bits (361), Expect: 7.87623e-33
Length: 312, Idn/Pos/Gap = 89/167/22 (28%/53%/7%)

Query:  35 VMLRSVPAP--APGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPM-----IIGHESAG  87
           V+++ VP P  +  +V +Q+  +GICGSD+        G +R  +P+     I+GHE  G
Sbjct:  16 VVVKEVPYPEKSDNDVLIQVESMGICGSDI--------GAYRGTNPLVTYPRILGHEIVG  67

Query:  88 VVEALGAGVTS-LQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYV 146
            V   G G+   ++VGDRV ++P V C QC  C  GR N C ++K      +DG +   +
Sbjct:  68 RVIESGIGMPDRVRVGDRVIVDPYVFCGQCYPCSIGRTNCCESLKVIGV-HIDGGMQEVI 126

Query: 147 CHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAK 206
            HPA    ++P+++ + +  + EPL++A+HA  R     G  ++++GAG IGL+  + A 
Sbjct: 127 RHPAHLLTKVPDNLPIHQLPLAEPLTIALHALHRTTLKSGEHIVIIGAGAIGLMAALAAV 186

Query: 207 AFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCA 266
            +GA I ++ DI ++RL +A++  G + ++N     + D    +++   G  A++ ++ +
Sbjct: 187 QYGA-IPILVDILEQRLEYAKS-LGIEHIVNPH---KEDDIKRIKEITSGRMAEVVMEAS 241

Query: 267 GLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALL 326
           G   +++  +H     GRI L G   +   +P    + +E++I+G       +   + +L
Sbjct: 242 GANISIKNTLHYTSFAGRIALTGWPKTETPLPTNLITFKELNIYGSRTSKGEFEEALDML 301

Query: 327 ASGRVNVKPLIT 338
           A+ ++N   +IT
Sbjct: 302 ATNKINASHIIT 313

dbj|BAB03906.1| sorbitol dehydrogenase [Bacillus halodurans C-125]
ref|NP_241053.1| sorbitol dehydrogenase [Bacillus halodurans C-125]
pir||C83673 sorbitol dehydrogenase gutB [imported] - Bacillus halodurans (strain C-125)
(354 aa)

Score: 143 bits (361), Expect: 8.00877e-33
Length: 344, Idn/Pos/Gap = 108/165/31 (31%/47%/9%)

Query:  37 LRSVPAPAPG-----EVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEA  91
           LR    PAP      ++ ++++ VGICGSD+  +     GP+     M  GHE AG V  
Sbjct:  12 LRFEETPAPSIEHDDDIIIKVKAVGICGSDLSRY--KKLGPYV--PGMTFGHEFAGEVVK  67

Query:  92 LGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFF-ATPPVDGSLARYVCHPA 150
           +G  VT   +GDRVA  P   C QC+ C+ G    C  +    A  P  G+ A YV  PA
Sbjct:  68 IGRSVTGFSIGDRVAACPTYTCGQCRYCQLGEPTRCERLSVIGARHP--GAYAEYVKLPA 125

Query: 151 AWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGA 210
                LP  V+ +E A+ EP SV  H   R     G+ V ++G G IGLL    AK FGA
Sbjct: 126 KHVIPLPNVVNYDEAALIEPASVVAHGFYRTNIKPGASVAIMGVGSIGLLAVQWAKIFGA 185

Query: 211 SIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLES 270
           + +   DID+++L  A    GAD +I++     H   L   +  +G   D+A++ AG  S
Sbjct: 186 TTVFAIDIDEQKLNVA-NQLGADVLISSLQRPAHKQIL---EYTNGIGVDVAVESAGTPS 241

Query: 271 TMRLAMHVVRPGGRICLVGMGSSAMHVP---LVDASSREIDIFGVFR-YSNTYP-----T 321
           T      + + GG +  +G+  + + +           E+ ++G +   S+ +P     T
Sbjct: 242 TSAQVFALPKKGGEVVFLGIPYADVQIERFYFEKIVRNELHVYGSWNALSSPFPGKEWAT 301

Query: 322 CIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVK 365
            I  ++SG++NV P+I++R        L    ET +  A G +K
Sbjct: 302 TIHYMSSGQLNVAPMISYRL------PLAKGPETFQQIAKGELK 339

ref|YP_207353.1| putative zinc-binding alcohol dehydrogenas [Neisseria gonorrhoeae FA 1090]
gb|AAW88941.1| putative zinc-binding alcohol dehydrogenas [Neisseria gonorrhoeae FA 1090]
(354 aa)

Score: 143 bits (360), Expect: 9.15259e-33
Length: 317, Idn/Pos/Gap = 95/154/15 (29%/48%/4%)

Query:  35 VMLRSVPAP--APGEVRLQMRCVGICGSDVHYWWHGS-----CG-PFRLHD---PMIIGH  83
           + +  +P P  APG V + +   GICG+D+H +  G      CG P  +     P+ +GH
Sbjct:  12 IRIEDIPEPTVAPGTVGINVAWCGICGTDLHEFMEGPIFIPPCGHPHPISGESAPVTMGH  71

Query:  84 ESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLA 143
           E +GVV A+G GV  ++VG  V +EP +            Y+L  ++ F       G L+
Sbjct:  72 EFSGVVYAVGEGVDDIKVGQHVVVEPYIIRDDVPTGEGSNYHLSKDMNFIGLGGCGGGLS 131

Query: 144 RYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCM 203
             +     W + + + + L++ A+ EPLSV  HA  R+G   G + LV GAGPIGLL   
Sbjct: 132 EKIAVKRRWVHPISDKIPLDQAALIEPLSVGHHAYVRSGAKAGDVALVGGAGPIGLLLAA 191

Query: 204 VAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIAL 263
           V KA G  +I +T++   R   A     AD ++   D  E D    V++  +G   D+A 
Sbjct: 192 VLKAKGIKVI-ITELSKARKDKARESGVADYIL---DPSEVDVVEEVKKLTNGEGVDVAF 247

Query: 264 DCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCI 323
           +C  +   +   +   +P   + +V + S    V +     +E+D+ G   Y N +   I
Sbjct: 248 ECTSVNKVLDTLVEACKPAANLVIVSIWSHPATVNVHSVVMKELDVRGTIAYCNDHAETI 307

Query: 324 ALLASGRVNVKPLITHR 340
            L+  G++N++P IT R
Sbjct: 308 KLVEEGKINLEPFITQR 324

ref|NP_416594.1| galactitol-1-phosphate dehydrogenase [Escherichia coli K12]
gb|AAC75152.1| galactitol-1-phosphate dehydrogenase; galactitol-1-phosphate dehydrogenase, NAD-binding [Escherichia coli K12]
gb|AAG57148.1| galactitol-1-phosphate dehydrogenase [Escherichia coli O157:H7 EDL933]
pir||B64976 galactitol-1-phosphate dehydrogenase (EC 1.1.1.-) - Escherichia coli (strain K-12)
dbj|BAB36317.1| galactitol-1-phosphate dehydrogenase [Escherichia coli O157:H7]
ref|NP_310921.1| galactitol-1-phosphate dehydrogenase [Escherichia coli O157:H7]
pir||H85835 galactitol-1-phosphate dehydrogenase [imported] - Escherichia coli (strain O157:H7, substrain EDL933)
pir||F90990 galactitol-1-phosphate dehydrogenase [imported] - Escherichia coli (strain O157:H7, substrain RIMD 0509952)
ref|NP_288593.1| galactitol-1-phosphate dehydrogenase [Escherichia coli O157:H7 EDL933]
sp|P37190|GATD_ECOLI Galactitol-1-phosphate 5-dehydrogenase
dbj|BAA15954.1| Galactitol-1-phosphate dehydrogenase (EC 1.1.1.-). [Escherichia coli]
(346 aa)

Score: 143 bits (360), Expect: 9.5425e-33
Length: 345, Idn/Pos/Gap = 109/171/45 (31%/49%/13%)

Query:  47 EVRLQMRCVGICGSDV--------HYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTS  98
           EVR+++   G+CGSD+        HY+            P+ +GHE +G ++A+G+GV  
Sbjct:  27 EVRVKIASSGLCGSDLPRIFKNGAHYY------------PITLGHEFSGYIDAVGSGVDD  74

Query:  99 LQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPE 158
           L  GD VA  P +PC  C  C +G Y+ C    F  +   DG  A Y+       + LP 
Sbjct:  75 LHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRR-DGGFAEYIVVKRKNVFALPT 133

Query: 159 SVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDI 218
            + +E+GA  EP++V +HA   A       V+++GAG IGLL    A A GA  +   DI
Sbjct: 134 DMPIEDGAFIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDI 193

Query: 219 DDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQAD-IALDCAGLESTMRLAMH 277
              +LA A++  GA    N+ ++    +A  +Q  L   + + + L+ AG+  T+ LA+ 
Sbjct: 194 SSEKLALAKSF-GAMQTFNSSEM----SAPQMQSVLRELRFNQLILETAGVPQTVELAVE 248

Query: 278 VVRPGGRICLVGMGSSAMHVPLVDAS-----SREIDIFGVF-RYSNTYP-----TCIALL 326
           +  P  ++ LVG     +H  L  A+      +E+ + G +  YS+ +P     T   LL
Sbjct: 249 IAGPHAQLALVGTLHQDLH--LTSATFGKILRKELTVIGSWMNYSSPWPGQEWETASRLL 306

Query: 327 ASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLTIP 371
              +++++PLI HR  G  ES  +A  + AR A  G V   L IP
Sbjct: 307 TERKLSLEPLIAHR--GSFESFAQAVRDIARNAMPGKV---LLIP 346

ref|ZP_00361900.1| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Polaromonas sp. JS666]
(346 aa)

Score: 143 bits (360), Expect: 1.04598e-32
Length: 342, Idn/Pos/Gap = 106/169/22 (30%/49%/6%)

Query:  25 GVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHE  84
            VL  P+ L++   + P  APGE+ L++R   +CG+D+           R   P +IGHE
Sbjct:   4 AVLRAPKVLQLSDIATPEAAPGELVLRVRAAMVCGTDLRILTGRKTKGVRF--PSVIGHE  61

Query:  85 SAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLAR 144
            AG V  +G GVT  + GDRV ++P +PC  C  C+ G  N+C + +       DG+ A 
Sbjct:  62 FAGEVVQVGDGVTQFKTGDRVCMDPVIPCRACAYCKTGHENVCLHRQAMGYE-FDGAFAE 120

Query: 145 YVCHPA-----AWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGL 199
           Y+  PA        + +P  +S E  A+ EPL+  ++  R AG  +G  V+VLGAGPIGL
Sbjct: 121 YIRIPAIALTAGNVFMMPAQMSFESAALAEPLACCINGQRNAGVQVGDTVVVLGAGPIGL 180

Query: 200 LNCMVAKAFGASIIVVTDIDDRRLAFAETHAGAD-AVINTRDLDEHDAALVVQQALDGAQ 258
           ++  +A+  GA  ++V++ +  R       A  D  V +  D         V+   DG  
Sbjct: 181 MHAALARLSGARQVIVSEPNAAR-----RQAAVDRGVEHMCDPSTESVMEFVKARTDGLG 235

Query: 259 ADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDAS---SREIDIFGVFRY 315
           AD+ +   G+      ++++VR GG + L   G SA     +D +     EI + G    
Sbjct: 236 ADVVILAIGVPQLANESLNLVRKGGHVNLFA-GFSAGETSNIDVNLIHYNEIVVTGASAL 294

Query: 316 -SNTYPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETA 356
               Y   + +L++G+++   LITHR+   E +   AAF+ A
Sbjct: 295 RRRDYELALNMLSAGQIDANSLITHRY---EVADSLAAFDEA 333

ref|NP_623939.1| Threonine dehydrogenase and related Zn-dependent dehydrogenases [Thermoanaerobacter tengcongensis MB4]
gb|AAM25543.1| Threonine dehydrogenase and related Zn-dependent dehydrogenases [Thermoanaerobacter tengcongensis MB4]
(350 aa)

Score: 142 bits (359), Expect: 1.07249e-32
Length: 311, Idn/Pos/Gap = 95/159/10 (30%/51%/3%)

Query:  35 VMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGA  94
           ++ + +P   P EV ++++   ICG+DVH +        R+  P  +GHE  G V  +G 
Sbjct:  22 IVKKEIPKIGPDEVLIKVKATSICGTDVHIYVWNEWAKSRIKPPKTMGHEFVGEVVEIGE  81

Query:  95 GVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCY 154
            VTS++VGD V+ E  + C +C+ CR G  ++C N         DG+ A Y+  P +  +
Sbjct:  82 NVTSVKVGDLVSAETHIVCGKCRACRTGNAHICENTLILGV-DTDGAFAEYIKVPESNVW 140

Query: 155 RLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIV 214
              +++ LE  ++ EPL  AVH    +G  +G  V V+G GPIG++   + K  GA+ I 
Sbjct: 141 INDKNIPLEILSIQEPLGNAVH-TVFSGDVVGKSVAVIGCGPIGMMAIPLLKRTGAAAIF 199

Query: 215 VTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRL 274
             +  D R   A    GA  VIN       D   +++   +G  AD+ LD +G  + +R 
Sbjct: 200 AIEPADYRRELAHK-LGATRVINPL---REDVVSIIKSETEGYGADVVLDFSGNPTAIRQ 255

Query: 275 AMHVVRPGGRICLVGMGSSAMHVPLV-DASSREIDIFGVF--RYSNTYPTCIALLASGRV 331
            +  +  GGR+ ++G+  + + + +  +   + I I G+   R  +T+ T   LL SG  
Sbjct: 256 GLEYIAKGGRMSILGLPDNEVPIDITNNVVFKGITIQGITGRRMYDTWYTVKGLLKSGLA 315

Query: 332 -NVKPLITHRF 341
            ++KP+ITH F
Sbjct: 316 EDLKPIITHTF 326

sp|Q8R7K0|TDH_THETN L-threonine 3-dehydrogenase
(347 aa)

Score: 142 bits (359), Expect: 1.08148e-32
Length: 311, Idn/Pos/Gap = 95/159/10 (30%/51%/3%)

Query:  35 VMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGA  94
           ++ + +P   P EV ++++   ICG+DVH +        R+  P  +GHE  G V  +G 
Sbjct:  19 IVKKEIPKIGPDEVLIKVKATSICGTDVHIYVWNEWAKSRIKPPKTMGHEFVGEVVEIGE  78

Query:  95 GVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCY 154
            VTS++VGD V+ E  + C +C+ CR G  ++C N         DG+ A Y+  P +  +
Sbjct:  79 NVTSVKVGDLVSAETHIVCGKCRACRTGNAHICENTLILGV-DTDGAFAEYIKVPESNVW 137

Query: 155 RLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIV 214
              +++ LE  ++ EPL  AVH    +G  +G  V V+G GPIG++   + K  GA+ I 
Sbjct: 138 INDKNIPLEILSIQEPLGNAVH-TVFSGDVVGKSVAVIGCGPIGMMAIPLLKRTGAAAIF 196

Query: 215 VTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRL 274
             +  D R   A    GA  VIN       D   +++   +G  AD+ LD +G  + +R 
Sbjct: 197 AIEPADYRRELAHK-LGATRVINPL---REDVVSIIKSETEGYGADVVLDFSGNPTAIRQ 252

Query: 275 AMHVVRPGGRICLVGMGSSAMHVPLV-DASSREIDIFGVF--RYSNTYPTCIALLASGRV 331
            +  +  GGR+ ++G+  + + + +  +   + I I G+   R  +T+ T   LL SG  
Sbjct: 253 GLEYIAKGGRMSILGLPDNEVPIDITNNVVFKGITIQGITGRRMYDTWYTVKGLLKSGLA 312

Query: 332 -NVKPLITHRF 341
            ++KP+ITH F
Sbjct: 313 EDLKPIITHTF 323

ref|NP_819162.1| L-threonine 3-dehydrogenase [Coxiella burnetii RSA 493]
gb|AAO89676.1| L-threonine 3-dehydrogenase [Coxiella burnetii RSA 493]
(342 aa)

Score: 142 bits (359), Expect: 1.23593e-32
Length: 335, Idn/Pos/Gap = 99/163/20 (29%/48%/5%)

Query:  37 LRSVPAPAPG--EVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGA  94
           L   P P PG  EV ++++   ICG+D+H +         +  PM +GHE  G +  +G 
Sbjct:  15 LHKAPTPKPGRDEVLIKIKKTAICGTDLHIYKWDEWAQKTIPVPMHVGHEFVGEIVEVGE  74

Query:  95 GVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCP-NIKFFATPPVDGSLARYVCHPAAWC 153
             ++L VGDRV+ E  + C  C+ CR G+ +LC   +      P  G+ A Y+  PA   
Sbjct:  75 AASALAVGDRVSGEGHITCGDCRNCRAGKRHLCRYTVGVGVNRP--GAFAEYLVIPAKNA 132

Query: 154 YRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASII 213
           Y++P  +S +  A+ +P   A H+       +G  VL+ GAGP+GL++  +A+  GA  +
Sbjct: 133 YKIPAKISDDIAAILDPFGNAAHSALEF-DLVGEDVLITGAGPVGLMSAAIARHVGARHV 191

Query: 214 VVTDIDDRRLAFAETHAGADAVINTRD--LDEHDAALVVQQALDGAQADIALDCAGLEST 271
           V+TD++D RLA AE   G  A +N+    L E    L + +       D+ L+ +G    
Sbjct: 192 VITDVNDYRLALAEK-VGVTAAVNSTKTPLTETMKNLGMTEGF-----DVGLEMSGNAEA 245

Query: 272 MRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVF--RYSNTYPTCIALLASG 329
            R  + V+  GG+I  +G+      +       + + I G++  R   T+     LL SG
Sbjct: 246 FRSMLTVMNNGGKIAFLGIPPEPFAIDWNQVVFKSLLIKGIYGRRMFETWYKMTNLLLSG 305

Query: 330 RVNVKPLITHRFMGLEESSLEAAFETARTAANGAV 364
            +++ P+ITH F        + AF+   +   G V
Sbjct: 306 -LDISPIITHEF---PMKDFQQAFDVMLSGKTGKV 336

gb|AAF96783.1| threonine 3-dehydrogenase [Vibrio cholerae O1 biovar eltor str. N16961]
ref|NP_233271.1| threonine 3-dehydrogenase [Vibrio cholerae O1 biovar eltor str. N16961]
pir||B82405 threonine 3-dehydrogenase VCA0885 [imported] - Vibrio cholerae (strain N16961 serogroup O1)
sp|Q9KL62|TDH_VIBCH L-threonine 3-dehydrogenase
(343 aa)

Score: 142 bits (359), Expect: 1.37753e-32
Length: 331, Idn/Pos/Gap = 95/165/20 (28%/49%/6%)

Query:  40 VPAPAPGEVRLQMRCVGICGSDVHYW----WHGSCGPFRLHDPMIIGHESAGVVEALGAG  95
           +P     ++ ++++   ICG+DVH +    W     P     PM++GHE  G V  +G  
Sbjct:  22 MPELGHNDLLIKIKKTAICGTDVHIYNWDEWSQKTIPV----PMVVGHEYVGEVVGIGQE  77

Query:  96 VTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYR 155
           V   Q+GDRV+ E  + C  C+ CR GR +LC N          G  + Y+  PA   ++
Sbjct:  78 VRGFQIGDRVSGEGHITCGHCRNCRGGRTHLCRNTIGVGVNRT-GCFSEYLVIPAFNAFK 136

Query: 156 LPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVV 215
           +P+ +S +  ++ +P   AVH    +   +G  VL+ GAGPIG++   VAK  GA  +V+
Sbjct: 137 IPDGISDDLASIFDPFGNAVH-TALSFDLVGEDVLITGAGPIGIMAAAVAKHVGARHVVI 195

Query: 216 TDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLA 275
           TD+++ RL  A       AV    ++ E +   V+++       D+ L+ +G+ S     
Sbjct: 196 TDVNEYRLDLARKMGVTRAV----NVAEQNLEDVMKELGMTEGFDVGLEMSGVPSAFSAM 251

Query: 276 MHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVF--RYSNTYPTCIALLASGRVNV 333
           +  +  GGRI L+G+  S+M +       + + I G++      T+    +L+ SG +++
Sbjct: 252 LKTMNHGGRIALLGIPPSSMAIDWNQVIFKGLVIKGIYGREMFETWYKMASLIQSG-LDI 310

Query: 334 KPLITHRFMGLEESSLEAAFETARTAANGAV 364
            P+ITH F   +    +  F+  R+ A+G V
Sbjct: 311 SPIITHHF---KVDDFQKGFDIMRSGASGKV 338

ref|NP_805252.1| putative alcohol dehydrogenase [Salmonella enterica subsp. enterica serovar Typhi Ty2]
ref|NP_455943.1| putative alcohol dehydrogenase [Salmonella enterica subsp. enterica serovar Typhi str. CT18]
emb|CAD01774.1| putative alcohol dehydrogenase [Salmonella enterica subsp. enterica serovar Typhi]
gb|AAO69101.1| putative alcohol dehydrogenase [Salmonella enterica subsp. enterica serovar Typhi Ty2]
pir||AE0675 probable alcohol dehydrogenase STY1520 [imported] - Salmonella enterica subsp. enterica serovar Typhi (strain CT18)
(341 aa)

Score: 142 bits (358), Expect: 1.38908e-32
Length: 324, Idn/Pos/Gap = 93/163/21 (28%/50%/6%)

Query:  29 RPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPM-----IIGH  83
           +P E+       P     EV +++   GICGSD+        G FR  +P+     IIGH
Sbjct:  10 KPGEVETRWVDYPHKKENEVLIKVDAAGICGSDI--------GAFRGTNPLVTYPRIIGH  61

Query:  84 ESAGVVEALGAGVT-SLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSL 142
           E  G+V   G G+  +++ GDRV ++P + C  C  C  GR N C N+       +DG++
Sbjct:  62 EVTGIVLQEGTGMPDNIKKGDRVIVDPYIYCGHCYPCSVGRTNCCENLNVIGVH-IDGAM 120

Query: 143 ARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNC 202
              V HPA   +++P++V  E   + EPL++A+HA  RA    G  V ++GAG IGL+  
Sbjct: 121 QEVVTHPAHLIHKIPDNVPSEMAPLAEPLTIALHALHRANVKAGEYVAIIGAGAIGLMAA 180

Query: 203 MVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIA 262
           + A+ + A+ I++ DI + RL +A+   G   V+N  D    DA   ++    G  A + 
Sbjct: 181 LSARHYKATPILI-DIVEERLRYAQK-LGVPYVLNAADDQVIDA---IKNITHGTMAQVV 235

Query: 263 LDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTC 322
           ++ +G  S +R  + +    GRI   G       +P    + +E+D+ G    +  +   
Sbjct: 236 IEASGANSAIRNTLDLASFAGRISFTGWPKQETSLPTNLITYKELDLRGSRTSAGEFDEA 295

Query: 323 IALLASGRVNVKPLITHRFMGLEE 346
           + +L++  +N + +++ + + L+E
Sbjct: 296 LRMLSTLEINPQDVVS-KVVNLDE 318

dbj|BAD91189.1| NAD dependent sorbitol dehydrogenase [Pyrus communis]
(147 aa)

Score: 142 bits (358), Expect: 1.40071e-32
Length: 154, Idn/Pos/Gap = 74/103/11 (48%/66%/7%)

Query: 191 VLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVI----NTRDLDEHDA 246
           V+GAGPIGL+  + A+AFGA  IV+ D++D RL+ A++  GAD V+    N  D+ E  A
Sbjct:   1 VVGAGPIGLVTLLAARAFGAPRIVIADVNDERLSIAKS-LGADEVVRVSTNIEDVAEEVA  59

Query: 247 ALVVQQALDGAQADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSRE 306
              +Q+ L+    DI+ DCAG   T+  A+   RPGG +CLVGMG   M +PL   ++RE
Sbjct:  60 K--IQKVLENG-VDISFDCAGFNKTITTALSATRPGGTVCLVGMGQREMTLPL---ATRE 113

Query: 307 IDIFGVFRYSNTYPTCIALLASGRVNVKPLITHR 340
           +DI G+FRY NT+P C+  L SG+++VKPLITHR
Sbjct: 114 VDIIGIFRYQNTWPLCLEFLRSGKIDVKPLITHR 147

gb|AAQ12025.1| putative zinc-containing alcohol dehydrogenase [Mycobacterium sp. S65]
(341 aa)

Score: 142 bits (358), Expect: 1.48496e-32
Length: 312, Idn/Pos/Gap = 105/155/16 (33%/49%/5%)

Query:  35 VMLRSVPAPAP--GEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEAL  92
           V L SVP PAP  GEV +++   G+CG+D+H +     GP     P+++GHE +G +  +
Sbjct:  12 VGLTSVPDPAPQDGEVIIEVAATGLCGTDLHEY---VAGPTFSQPPVVLGHEVSGRIVEV  68

Query:  93 GAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAW 152
           GAGV   ++G+  A+ P   C  C  C    Y+LC    +      +G LA YV  P+  
Sbjct:  69 GAGVDQSRIGEGAAVIPMDFCGSCHYCHRSLYHLCQRPGWIGFTR-NGGLANYVAVPSRL 127

Query: 153 CYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASI 212
             R+P+ V LEE A+ EP +VA HA RRA   +G  V+VLGAG +GL     A+A GA+ 
Sbjct: 128 AVRVPDVVDLEEAALTEPTAVAFHAVRRAELLLGETVMVLGAGALGLTVIQCARAAGAAR 187

Query: 213 IVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALV--VQQALDGAQADIALDCAGLES 270
           I VT+    R + A    GA  V     LD HD      + +   G   D+    AG   
Sbjct: 188 IFVTEPSGVRASLARD-LGATLV-----LDPHDPGTTACILEETRGVGVDVVFHVAGSAE 241

Query: 271 TMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYS--NTYPTCIALLAS 328
                +  +R  GR   +   + A  + +     +EI +  VF Y   + +P  +AL+A 
Sbjct: 242 AFTQGLDCLRKQGRFMEMSSWAGAASLDVNRHLLKEIQLRMVFGYDMFDDFPAVLALIAD 301

Query: 329 GRVNVKPLITHR 340
           G++ + P IT R
Sbjct: 302 GKLALAPQITAR 313

ref|NP_807433.1| threonine 3-dehydrogenase [Salmonella enterica subsp. enterica serovar Typhi Ty2]
ref|NP_458219.1| threonine 3-dehydrogenase [Salmonella enterica subsp. enterica serovar Typhi str. CT18]
emb|CAD03286.1| threonine 3-dehydrogenase [Salmonella enterica subsp. enterica serovar Typhi]
gb|AAO71293.1| threonine 3-dehydrogenase [Salmonella enterica subsp. enterica serovar Typhi Ty2]
pir||AB0974 L-threonine 3-dehydrogenase (EC 1.1.1.103) - Salmonella enterica subsp. enterica serovar Typhi (strain CT18)
sp|Q8Z2F4|TDH_SALTI L-threonine 3-dehydrogenase
(341 aa)

Score: 142 bits (357), Expect: 1.81419e-32
Length: 316, Idn/Pos/Gap = 97/159/21 (30%/50%/6%)

Query:  35 VMLRSVPAPAPG--EVRLQMRCVGICGSDVHYW----WHGSCGPFRLHDPMIIGHESAGV  88
           + +  VP P  G  ++ +++R   ICG+DVH +    W     P     PM++GHE  G 
Sbjct:  13 IWMTDVPEPEVGHNDLLIKIRKTAICGTDVHIYNWDEWSQKTIPV----PMVVGHEYVGE  68

Query:  89 VEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCH 148
           V  +G  V   ++GDRV+ E  + C  C+ CR GR +LC N          G  A Y+  
Sbjct:  69 VVGIGQEVKGFKIGDRVSGEGHITCGHCRNCRGGRTHLCRNTTGVGVNR-PGCFAEYLVI 127

Query: 149 PAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAF 208
           PA   +++P+++S +  ++ +P   AVH    +   +G  VLV GAGPIG++   VAK  
Sbjct: 128 PAFNAFKIPDNISDDLASIFDPFGNAVH-TALSFDLVGEDVLVSGAGPIGVMAAAVAKHV 186

Query: 209 GASIIVVTDIDDRRLAFAETHAGADAV-INTRDLDEHDAALVVQQALDGAQADIALDCAG 267
           GA  +V+TD+++ RL  A       AV +    L++  A L + +       D+ L+ +G
Sbjct: 187 GARHVVITDVNEYRLELARKMGVTRAVNVAKESLNDVMAELGMTEGF-----DVGLEMSG 241

Query: 268 LESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVF--RYSNTYPTCIAL 325
                R  +  +  GGRI ++G+  S M +       + + I G++      T+    AL
Sbjct: 242 APPAFRTMLDTMNHGGRIAMLGIPPSDMSIDWTKVIFKGLFIKGIYGREMFETWYKMAAL 301

Query: 326 LASGRVNVKPLITHRF 341
           + SG +++ P+ITHRF
Sbjct: 302 IQSG-LDLSPIITHRF 316

gb|AAT51753.1| zinc-dependent dehydrogenase [Mycobacterium vanbaalenii]
(341 aa)

Score: 141 bits (356), Expect: 2.36941e-32
Length: 312, Idn/Pos/Gap = 105/154/16 (33%/49%/5%)

Query:  35 VMLRSVPAPAP--GEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEAL  92
           V L SVP PAP  GEV +++   G+CG+D+H +     GP     P+++GHE +G +  +
Sbjct:  12 VGLTSVPDPAPQDGEVIIEVAATGLCGTDLHEY---VAGPTFSQPPVVLGHEVSGRIVEV  68

Query:  93 GAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAW 152
           GAGV   ++G   A+ P   C  C  C    Y+LC    +      +G LA YV  P+  
Sbjct:  69 GAGVDQSRIGQGAAVIPMDFCGSCHYCHRSLYHLCQRPGWIGFTR-NGGLANYVAVPSRL 127

Query: 153 CYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASI 212
             R+P+ V LEE A+ EP +VA HA RRA   +G  V+VLGAG +GL     A+A GA+ 
Sbjct: 128 AVRVPDVVDLEEAALTEPTAVAFHAVRRAELLLGETVMVLGAGALGLTVIQCARAAGAAR 187

Query: 213 IVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALV--VQQALDGAQADIALDCAGLES 270
           I VT+    R + A    GA  V     LD HD      + +   G   D+    AG   
Sbjct: 188 IFVTEPSGVRASLARD-LGATLV-----LDPHDPGTTACILEETRGVGVDVVFHVAGSAE 241

Query: 271 TMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYS--NTYPTCIALLAS 328
                +  +R  GR   +   + A  + +     +EI +  VF Y   + +P  +AL+A 
Sbjct: 242 AFTQGLDCLRKQGRFMEMSSWAGAASLDVNRHLLKEIQLRMVFGYDMFDDFPAVLALIAD 301

Query: 329 GRVNVKPLITHR 340
           G++ + P IT R
Sbjct: 302 GKLALAPQITAR 313

emb|CAA56231.1| Gat-1-P-DH, NAD dependent [Escherichia coli]
(346 aa)

Score: 141 bits (355), Expect: 3.42042e-32
Length: 342, Idn/Pos/Gap = 105/165/39 (30%/48%/11%)

Query:  47 EVRLQMRCVGICGSDV--------HYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTS  98
           EVR+++   G+CGSD+        HY+            P+ +GHE +G ++A+G+GV  
Sbjct:  27 EVRVKIASSGLCGSDLPRIFKNGAHYY------------PITLGHEFSGYIDAVGSGVDD  74

Query:  99 LQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPE 158
           L  GD VA  P +PC  C  C +G Y+ C    F  +   DG  A Y+       + LP 
Sbjct:  75 LHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRR-DGGFAEYIVVKRKNVFALPT 133

Query: 159 SVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDI 218
            + +E+GA  EP++V +HA   A       V+++GAG IGLL    A A GA  +   DI
Sbjct: 134 DMPIEDGAFIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDI 193

Query: 219 DDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHV 278
              +LA A++  GA    N+ ++       V++   D     + L+ AG+  T+ LA+ +
Sbjct: 194 SSEKLALAKSF-GAMQTFNSLEMSAPQMQGVLR---DVRFNQLILETAGVPQTVELAVEI 249

Query: 279 VRPGGRICLVGMGSSAMHVPLVDASS---REIDIFGVF-RYSNTYP-----TCIALLASG 329
             P  ++ LVG     +H+          +E+ + G +  YS+ +P     T   LL   
Sbjct: 250 AGPHAQLALVGTLHQDLHLTSTTFGKILRKELTVIGSWMNYSSPWPGQEWETASRLLTER 309

Query: 330 RVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLTIP 371
           +++++PLI HR  G  ES  +   + AR A  G V   L IP
Sbjct: 310 KLSLEPLIAHR--GSFESFTQVVRDIARNAMPGKV---LLIP 346

gb|EAA66355.1| hypothetical protein AN9288.2 [Aspergillus nidulans FGSC A4]
ref|XP_413425.1| hypothetical protein AN9288.2 [Aspergillus nidulans FGSC A4]
(382 aa)

Score: 140 bits (354), Expect: 4.21377e-32
Length: 316, Idn/Pos/Gap = 102/161/25 (32%/50%/7%)

Query:  47 EVRLQMRCVGICGSDVHYWWHGSC--------GPFRLHD-PMIIGHESAGVVEALGAGVT  97
           EVR+Q+   GICGSD+H +  G           P+   + P+ +GHE +G +  LG+ V 
Sbjct:  30 EVRIQIAYCGICGSDIHEYLGGPVFSPPPGKKNPYTGAELPVTLGHEISGTIVELGSSVP  89

Query:  98 S----LQVGDRVALEPGVP-----CLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCH 148
           +    L++G RVA+ P +        +C  C+ G  N+C     +      G LA  +  
Sbjct:  90 ASDPNLKLGMRVAVNPAMNDRHHGVEKCTACQLGLPNICKRYTSYGFSAAGGGLASEIVV 149

Query: 149 PAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAF 208
               C  LP+S+SL+ GA+ EPL+VA H  R +G      VL+LGAGPIGL   M+ + +
Sbjct: 150 KHYACIPLPDSISLKVGALLEPLAVAWHCIRISGFQRDQTVLILGAGPIGLAILMILRVW 209

Query: 209 GASIIVVTDIDDRRLAFAETHAGADAVINTRDL----DEHDAALV-VQQALDGAQADIAL 263
           G   +V++++   R   A    GAD V++  +L    D  D  +V  Q+A+    AD+  
Sbjct: 210 GVKTVVISEVAASRKRMAR-ELGADLVLDPTELGSSKDGLDPVVVATQKAMKADGADVTF 268

Query: 264 DCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNT-YPTC 322
           DC GL+ST+  A+   RPGG +  V +    + V L + +  E  + G   Y++  +   
Sbjct: 269 DCTGLQSTLDTAIAATRPGGTVFNVAIHEKPLMVNLNELTLGERRLTGGICYTDVDFQEL 328

Query: 323 IALLASGRVNVKPLIT 338
           IA L +G++  + LIT
Sbjct: 329 IAALEAGKIQAERLIT 344

ref|YP_154661.1| Threonine 3-dehydrogenase [Idiomarina loihiensis L2TR]
gb|AAV81112.1| Threonine 3-dehydrogenase [Idiomarina loihiensis L2TR]
(341 aa)

Score: 140 bits (353), Expect: 5.45763e-32
Length: 338, Idn/Pos/Gap = 99/170/22 (29%/50%/6%)

Query:  35 VMLRSVPAPAPG--EVRLQMRCVGICGSDVHYW----WHGSCGPFRLHDPMIIGHESAGV  88
           + +  V  P  G  ++ ++++   ICG+DVH +    W     P     PM++GHE  G 
Sbjct:  13 IWMTDVEKPECGYNDLLIKIKKTAICGTDVHIYKWDDWSQKTIPV----PMVVGHEYVGE  68

Query:  89 VEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCH 148
           V A+G GV   ++GDRV+ E  + C  C+ CR GR +LC N  +       G+ A Y+  
Sbjct:  69 VAAMGDGVRGFEIGDRVSGEGHITCGHCRNCRAGRRHLCRN-TYGVGVNRPGAFAEYLAL 127

Query: 149 PAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAF 208
           PA   ++LP+ V+ E  A+ +P   AVH    A   +G  VL+ GAGPIG++   VA+  
Sbjct: 128 PAENAFKLPDDVTDEMAAVFDPFGNAVH-TALAFDLVGEDVLITGAGPIGIMAAAVARHV 186

Query: 209 GASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGL 268
           GA  +V+TD+++ RL  A       AV    D+ +   + V+ +       D+ L+ +G+
Sbjct: 187 GARHVVITDVNEYRLDLARKMGVTRAV----DVSKEKLSDVMTELGMKEGFDVGLEMSGV 242

Query: 269 ESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVF--RYSNTYPTCIALL 326
            S     +  +  GG+I ++G+    + +       + + I G++      T+    +LL
Sbjct: 243 PSAFSQMLETMNHGGKIAMLGIPPENIAIDWNQVIFKGLVIKGIYGREMFETWYKMASLL 302

Query: 327 ASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAV 364
            SG +++ P++TH  M +++   E  FET  +  +G V
Sbjct: 303 QSG-LDISPILTHE-MPIDD--FEKGFETMISGQSGKV 336

ref|ZP_00092612.2| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Azotobacter vinelandii]
(350 aa)

Score: 140 bits (353), Expect: 5.7378e-32
Length: 351, Idn/Pos/Gap = 101/167/21 (28%/47%/5%)

Query:  30 PRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYW------WHGSCGPFRLHDPMIIGH  83
           P + R+   +VP   PGE+  ++   GIC  D+  +      W     P  +  PMI GH
Sbjct:   9 PGDYRLEEVAVPKAGPGEIIAKVEACGICAGDIKSFGGAPSFWGDETQPAYIKAPMIPGH  68

Query:  84 ESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFA-TPPVDGSL 142
           E    +  LG GV   ++GDRV  E  VPC  C+ C+ G Y +C     +     V+G++
Sbjct:  69 EFIAHIVELGKGVEGYELGDRVISEQIVPCWNCRFCKRGHYWMCQKHDLYGFQNNVNGAM 128

Query: 143 ARYV-CHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLN 201
           A Y+     +  Y++P  + +E+  + EP + ++HA +RA    G +V++ GAG +GL  
Sbjct: 129 AEYIRFTKESINYKVPRDLPIEKAVLIEPYACSMHAVQRAQIQFGDVVVLAGAGTLGLGM 188

Query: 202 CMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADI 261
              AK  G   +VV D+ + RL  A+   GAD VIN     + D    +++  DG   D+
Sbjct: 189 IGAAKKAGPGKLVVMDLFEDRLELAKKF-GADLVINPA---KEDPVARIKEITDGYGCDV 244

Query: 262 ALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSR-EIDIFGVFRYSNTYP 320
            ++  G   ++   + ++R  GR     +    + V     S R E+D+ G       YP
Sbjct: 245 YIEATGHPKSVEQGLSMIRNLGRFVEFSVFKDPVTVDWSIISDRKELDVLGAHLGPYCYP 304

Query: 321 TCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANG--AVKVMLT 369
             I  +A G +  + ++TH F       LE   +  + A +G  ++KV+LT
Sbjct: 305 LVIEGIADGSLPTEGVVTHNF------PLERFMDGFKLAMSGKDSLKVILT 349

emb|CAC49546.1| putative sugar-alcohol dehydrogenase, probably galactitol-1-phosphate 5-dehydrogenase protein [Sinorhizobium meliloti 1021]
ref|NP_437686.1| putative sugar-alcohol dehydrogenase, probably galactitol-1-phosphate 5-dehydrogenase protein [Sinorhizobium meliloti 1021]
pir||B95985 probable sugar-alcohol dehydrogenase, probably galactitol-1-phosphate 5-dehydrogenase protein (EC 1.1.1.-) [imported] - Sinorhizobium meliloti (strain 1021) magaplasmid pSymB
(339 aa)

Score: 140 bits (353), Expect: 6.44877e-32
Length: 266, Idn/Pos/Gap = 87/140/18 (32%/52%/6%)

Query:  26 VLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHES  85
           VL  P ++R+  R  P   PGEV L++  VG+CGSD+        G +++  P+I GHE 
Sbjct:   5 VLHAPGDIRLETRPKPVAGPGEVLLRVASVGVCGSDLPRMLVK--GAWKM--PLITGHEF  60

Query:  86 AGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARY 145
           +G + ALG  V   ++G+  A+ P +PC QC  C+ G ++ C +  +F +   DG+ A +
Sbjct:  61 SGHIHALGENVEGWEIGELTAIAPLMPCNQCIECKTGNFSRCRDYDYFGSRR-DGAYAEF 119

Query: 146 VCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRA-GTTIGSLVLVLGAGPIGLLNCMV 204
           V  P     + P+ V     AM +P S+A+HA  +A G T G    V+G GPIGL     
Sbjct: 120 VAVPVENLIKTPQHVDPRAIAMTDPASIALHAIWKAGGITAGQTGAVVGCGPIGLFAIQW 179

Query: 205 AKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALD 264
            +  G S ++  D+ + +LA A   AGAD  I + D            A +  +AD+ ++
Sbjct: 180 MRIMGTSRVIAVDVTEEKLALAR-QAGADLCILSADF-----------ADNKERADLVIE 227

Query: 265 CAGLESTMRLAMHVVRPGGRICLVGM 290
             G++ST+  A+ +  PGG +  +G+
Sbjct: 228 AVGIDSTINAAVMLAAPGGHVTFIGI 253

gb|EAL21912.1| hypothetical protein CNBC0530 [Cryptococcus neoformans var. neoformans B-3501A]
gb|AAW42610.1| xylitol dehydrogenase, putative [Cryptococcus neoformans var. neoformans JEC21]
ref|XP_569917.1| xylitol dehydrogenase, putative [Cryptococcus neoformans var. neoformans JEC21]
(469 aa)

Score: 140 bits (353), Expect: 6.44877e-32
Length: 173, Idn/Pos/Gap = 68/105/0 (39%/60%/0%)

Query:  57 ICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQC 116
           ICGSD+H +  G  G   + +P+++GHES+G V A+G  V + +VGDRVA+EPG+PC +C
Sbjct:  81 ICGSDLHNYLAGGVGGRPVTEPIVMGHESSGEVIAVGDLVKTHKVGDRVAIEPGLPCRRC 140

Query: 117 QRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVH 176
             C+EG+ N+C N+ +   P   GSL+RY   PA     +P+ +S EE    +PL+V + 
Sbjct: 141 INCKEGKVNICLNMHYCGAPGSVGSLSRYFALPADMAPHIPDHLSWEEAGCIQPLAVGIQ 200

Query: 177 ANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFAETH 229
             +R        V + G GPIGL++  VA A+ A  I+  D + +R+ FA+ +
Sbjct: 201 VGKRVDLRPHKTVAIFGCGPIGLISAAVAHAYSARKIIAFDNNPQRVEFAKKY 253


Score: 48 bits (114), Expect: 0.000272988
Length: 111, Idn/Pos/Gap = 35/62/7 (31%/55%/6%)

Query: 260 DIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHV-PLVDASSREIDIFGVFRYSNT 318
           D  ++  G E  M + + + + GG    VG+G    +  P +  +++EI++ G+ RY+ +
Sbjct: 356 DRVVEATGAEDCMLMGIAIAKQGGNYLAVGLGHIQTNCFPTLAVTNKEINVMGITRYTAS 415

Query: 319 -YPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVML 368
            +P+ + LL+ G V+VK LIT  F  L +S+   AFE    AA   +KV++
Sbjct: 416 CFPSALDLLSRGVVDVKQLITKTF-PLTQST--EAFEA--VAAGQDMKVVI 461

ref|ZP_00330709.1| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Moorella thermoacetica ATCC 39073]
(350 aa)

Score: 140 bits (353), Expect: 6.83663e-32
Length: 353, Idn/Pos/Gap = 106/162/19 (30%/45%/5%)

Query:  26 VLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHG--SCGPFRLHDPMIIGH  83
           VL  P ++R++ + VP P PGEV +++   GICG+DV     G     P+        GH
Sbjct:   5 VLFGPNDVRLVEKPVPKPGPGEVLVRVAACGICGTDVKIITKGMPKMPPY---GEFTFGH  61

Query:  84 ESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFF------ATPP 137
           E AG + ALG  V   QVGDRVA+E    C +C+ C +G+Y  C N          A   
Sbjct:  62 EWAGTIVALGETVDEFQVGDRVAIEAHKGCGRCENCIDGKYTACLNYGRLDKGHRAAGMT 121

Query: 138 VDGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTI-GSLVLVLGAGP 196
           VDG  A Y        Y++P++++  E         A++A  ++G  I G  VLV+G GP
Sbjct: 122 VDGGFAEYAVQHVNSVYKIPDNITFNEATYVTTAGCALYAIDKSGGYIAGDTVLVIGPGP 181

Query: 197 IGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDG 256
           IGL     A++ GA  I++    + RL       GA   IN R++   D    V     G
Sbjct: 182 IGLSVVQGARSLGAEKIILMGTREDRLVKGR-ELGATHTINIREV--ADPVAEVMAITGG 238

Query: 257 AQADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYS 316
                  +CAG   +    +   + GG + LV      +   L      +I +  V    
Sbjct: 239 KGCKRVFECAGNSQSFEYGIKAAKKGGVMVLVSFYKEPVMANLDYVVLNQISLLTVRGEG 298

Query: 317 N-TYPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVML 368
           N      ++L+A G+++ KP++TH F  LEE   +   +      +GA+KV++
Sbjct: 299 NQNCKRALSLMAQGKIDAKPIMTHAF-PLEE--FQKGLDYFVNRKDGAMKVVI 348

ref|YP_189588.1| sorbitol dehydrogenase, putative [Staphylococcus epidermidis RP62A]
gb|AAW52858.1| sorbitol dehydrogenase, putative [Staphylococcus epidermidis RP62A]
(350 aa)

Score: 140 bits (352), Expect: 6.89391e-32
Length: 319, Idn/Pos/Gap = 104/160/23 (32%/50%/7%)

Query:  31 RELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHD----------PMI  80
           +++RV  R   A    EV++++   GICG+D+H +  G    F   D          P+ 
Sbjct:  10 KDVRVEDREPKAIKDNEVQVKVSWAGICGTDLHEYLEGPI--FISTDQPDPLLGQTAPVT  67

Query:  81 IGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDG 140
           +GHE +GVVE +G  V+  + GDRV + P V     +R +    +L     F      DG
Sbjct:  68 LGHEFSGVVENVGKDVSRFKKGDRVVVNPTVS----KREKPENVDLYDGYSFIGLGS-DG 122

Query: 141 SLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLL 200
           + A +   P    Y LP++VS  EGA+ EP +VAV A +      G  V V GAGPIGLL
Sbjct: 123 AFAEFTNAPETNVYHLPDNVSAREGALVEPTAVAVQAVKEGELLFGDTVAVFGAGPIGLL 182

Query: 201 NCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQAD 260
             + AKA GAS I V D+ + RLA A++  GA  V N+ ++D      V +   +G   D
Sbjct: 183 TIVAAKAAGASKIFVFDLSEERLAKAKS-VGATHVYNSGNVDP--VQTVYEHTDNG--VD 237

Query: 261 IALDCAGLESTMRLAMHVVRPGGRICLVGM-GSSAMHVPLVDASSREIDIFGVFRYSNTY 319
           ++ + AG+  T++ ++ V RP G   +V + G      PL+  +        +     T+
Sbjct: 238 VSFEVAGVGITLQQSIEVTRPRGTAVIVSIFGHPVEFNPLLQMNKGVKLTTTIAYTPTTF 297

Query: 320 PTCIALLASGRVNVKPLIT 338
              I L+A+G +NVK ++T
Sbjct: 298 QQTIDLIANGSLNVKDVVT 316

prf||2113201F carbohydrate phosphotransferase II
(346 aa)

Score: 140 bits (352), Expect: 7.68375e-32
Length: 342, Idn/Pos/Gap = 105/164/39 (30%/47%/11%)

Query:  47 EVRLQMRCVGICGSDV--------HYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTS  98
           EVR+++   G+CGSD+        HY+            P+ +GHE +G ++A+G+GV  
Sbjct:  27 EVRVKIASSGLCGSDLPRIFKNGAHYY------------PITLGHEFSGYIDAVGSGVDD  74

Query:  99 LQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPE 158
           L  GD VA  P +PC  C  C  G Y+ C    F  +   DG  A Y+       + LP 
Sbjct:  75 LHPGDAVACVPLLPCFTCPECLYGFYSQCAKYDFIGSRR-DGGFAEYIVVKRKNVFALPT 133

Query: 159 SVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDI 218
            + +E+GA  EP++V +HA   A       V+++GAG IGLL    A A GA  +   DI
Sbjct: 134 DMPIEDGAFIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDI 193

Query: 219 DDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHV 278
              +LA A++  GA    N+ ++       V++   D     + L+ AG+  T+ LA+ +
Sbjct: 194 SSEKLALAKSF-GAMQTFNSLEMSAPQMQGVLR---DVRFNQLILETAGVPQTVELAVEI 249

Query: 279 VRPGGRICLVGMGSSAMHVPLVDASS---REIDIFGVF-RYSNTYP-----TCIALLASG 329
             P  ++ LVG     +H+          +E+ + G +  YS+ +P     T   LL   
Sbjct: 250 AGPHAQLALVGTLHQDLHLTSTTFGKILRKELTVIGSWMNYSSPWPGQEWETASRLLTER 309

Query: 330 RVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLTIP 371
           +++++PLI HR  G  ES  +   + AR A  G V   L IP
Sbjct: 310 KLSLEPLIAHR--GSFESFTQVVRDIARNAMPGKV---LLIP 346

ref|NP_765574.1| sorbitol dehydrogenase [Staphylococcus epidermidis ATCC 12228]
gb|AAO05660.1| sorbitol dehydrogenase [Staphylococcus epidermidis ATCC 12228]
(350 aa)

Score: 139 bits (351), Expect: 9.78721e-32
Length: 319, Idn/Pos/Gap = 103/160/23 (32%/50%/7%)

Query:  31 RELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHD----------PMI  80
           +++RV  R   A    EV++++   GICG+D+H +  G    F   D          P+ 
Sbjct:  10 KDVRVEDREPKAIKDNEVQVKVSWAGICGTDLHEYLEGPI--FISTDQPDPLLGQTAPVT  67

Query:  81 IGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDG 140
           +GHE +GV+E +G  V+  + GDRV + P V     +R +    +L     F      DG
Sbjct:  68 LGHEFSGVIENVGKDVSRFKKGDRVVVNPTVS----KREKPENVDLYDGYSFIGLGS-DG 122

Query: 141 SLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLL 200
           + A +   P    Y LP++VS  EGA+ EP +VAV A +      G  V V GAGPIGLL
Sbjct: 123 AFAEFTNAPETNVYHLPDNVSAREGALVEPTAVAVQAVKEGELLFGDTVAVFGAGPIGLL 182

Query: 201 NCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQAD 260
             + AKA GAS I V D+ + RLA A++  GA  V N+ ++D      V +   +G   D
Sbjct: 183 TIVAAKAAGASKIFVFDLSEERLAKAKS-VGATHVYNSGNVDP--VQTVYEHTDNG--VD 237

Query: 261 IALDCAGLESTMRLAMHVVRPGGRICLVGM-GSSAMHVPLVDASSREIDIFGVFRYSNTY 319
           ++ + AG+  T++ ++ V RP G   +V + G      PL+  +        +     T+
Sbjct: 238 VSFEVAGVGITLQQSIEVTRPRGTAVIVSIFGHPVEFNPLLQMNKGVKLTTTIAYTPTTF 297

Query: 320 PTCIALLASGRVNVKPLIT 338
              I L+A+G +NVK ++T
Sbjct: 298 QQTIDLIANGSLNVKDVVT 316

ref|YP_177108.1| Zn-dependent alcohol dehydrogenase [Bacillus clausii KSM-K16]
dbj|BAD66147.1| Zn-dependent alcohol dehydrogenase [Bacillus clausii KSM-K16]
(362 aa)

Score: 139 bits (350), Expect: 1.19571e-31
Length: 349, Idn/Pos/Gap = 100/168/18 (28%/48%/5%)

Query:  30 PRELRVMLRSVPA-PAPGEVRLQMRCVGICGSDVH------YWWHGSCGPFRLHDPMIIG  82
           P++ R+    VP      E+ +++   GIC  D+        +W     P  +  PMI G
Sbjct:  17 PKDYRLEEVDVPVIEHDKEIIVKVEATGICAGDIKAFDGAPSFWGDDTQPAYIKAPMIPG  76

Query:  83 HESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFA-TPPVDGS 141
           HE  G V A G GV   ++GDR+  E  VPC +C+ C  G+Y +C     +     V+GS
Sbjct:  77 HEFIGHVVAKGDGVGDFEIGDRIISEQIVPCWECRFCNRGQYWMCEKHDLYGFQNNVNGS 136

Query: 142 LARYV-CHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLL 200
           +A Y+     A  Y++P  + +E+  + EP + ++HA +RA   +G +V++ GAG +GL 
Sbjct: 137 MAEYMKFTKEAINYKVPADLPIEQAILIEPYACSMHAVQRARIELGDIVVLSGAGTLGLG 196

Query: 201 NCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQAD 260
                K  GA  +VV D+ D RLA A+   GAD V+N     + +    V+   DG   D
Sbjct: 197 MIGAVKKSGAKTLVVLDLKDERLALAQ-QFGADVVLNPA---KDNVVEKVKDMTDGYGCD 252

Query: 261 IALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSR-EIDIFGVFRYSNTY 319
           + ++  G  +++   + ++R  GR     +    + V     S R E+D+ G       Y
Sbjct: 253 VYIEATGHPASVEQGLSMIRKLGRFVEFSVFKDPVTVDWSIISDRKELDVLGSHLGPYCY 312

Query: 320 PTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVML 368
           P  I  +A+G +  + ++TH    L        FE  +  +N ++K++L
Sbjct: 313 PLVIEGIANGDLPTEGVVTHE---LPLERFAEGFELMKNGSN-SLKIIL 357

ref|ZP_00319582.1| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Oenococcus oeni PSU-1]
(337 aa)

Score: 139 bits (350), Expect: 1.41286e-31
Length: 304, Idn/Pos/Gap = 91/151/21 (29%/49%/6%)

Query:  41 PAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQ 100
           P P   EV +++  VG+CG+D    + G  G      P+++GHE +G V  +G  VT+ +
Sbjct:  20 PTPKNNEVLIKVAYVGVCGTD-KALYQGLPGSADAVPPIVLGHEDSGTVVEIGESVTNFE  78

Query: 101 VGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPESV 160
           VGDRVA++P + C +C  CR  R  LC N+        +G L  YV  P    Y+LP++V
Sbjct:  79 VGDRVAIDPNIYCHKCDFCRTNRPELCTNLSAVGVTR-NGGLEEYVAVPEEVAYKLPDNV 137

Query: 161 SLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDI-- 218
           S ++ A+ EPLS  VH             +VLG G  G L     KA+G S + ++    
Sbjct: 138 SFKQAALTEPLSCVVHGVDLLAIKPFQEAIVLGDGFTGQLFVKTLKAYGVSKVTISTRHL 197

Query: 219 -DDRRLAFAETHAGADAVINTRDLD-EHDAALVVQQALDGAQADIALDCAGLESTMRLAM 276
            D++ + F +   GAD V++ R  D + D  +VV+       AD+       E  ++ A 
Sbjct: 198 DDEKHVDFLKKVVGADEVVDARSNDFDKDYDVVVEAV---GSADVQ------EQAVKAAA 248

Query: 277 HVVRPGGRICLVGMG--SSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASGRVNVK 334
           H    GG++ + G+G       V   +   +++ + G F    T+   IA++A+G+++  
Sbjct: 249 H----GGQVLMFGVGKPEQKFSVSSYEIFQKQLTVQGSFINPYTFKAAIAMIAAGKIDPS 304

Query: 335 PLIT 338
            L++
Sbjct: 305 ELVS 308

ref|YP_015231.1| alcohol dehydrogenase, zinc-dependent [Listeria monocytogenes str. 4b F2365]
gb|AAT05408.1| alcohol dehydrogenase, zinc-dependent [Listeria monocytogenes str. 4b F2365]
(343 aa)

Score: 139 bits (349), Expect: 1.7261e-31
Length: 344, Idn/Pos/Gap = 117/172/30 (34%/50%/8%)

Query:  37 LRSVPAPA--PGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGA  94
           LR V  P     +V++++   GICGSD+H +      P     P+ +GHE +GVV  +G 
Sbjct:  16 LRDVEEPQVYGDKVKIKVAFTGICGSDIHTFKGEYKNP---TTPVTLGHEFSGVVVEVGP  72

Query:  95 GVTSLQVGDRVALEPGV-PCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWC 153
            VTS++VGDRV  E     C +C  C+E  YNLC N +   T   +GS A +V      C
Sbjct:  73 DVTSIKVGDRVTSETTFETCGECIYCKERDYNLCSNRRGIGT-QANGSFAEFVLSREESC 131

Query: 154 YRLPESVSLEEGAMCEPLSVAVHANRRAGTTI--GSLVLVLGAGPIGLLNCMVAKAFGAS 211
           + L E +SLE  A+ EPL+  VH+     TTI     VLV G GPIGLL   V KA GA+
Sbjct: 132 HVLDERISLEAAALTEPLACCVHSALEK-TTIRPDDTVLVFGPGPIGLLLAQVVKAQGAT 190

Query: 212 II---VVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGL 268
           +I   +  D D  RLA      G D +++T    + D A VV    DG  A+   DC+G 
Sbjct: 191 VIMAGITKDSDRLRLA---KELGMDRIVDTL---KEDLAEVVLGMTDGYGAERVFDCSGA 244

Query: 269 ESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASS---REIDIFGV-FRYSNTYPTCIA 324
              +   + + +  G    VG+ +   +   +D  S   REI   G   +  +++   + 
Sbjct: 245 VPAVNQGLPLTKKKGDFVQVGLFAEKKNA--IDEESIIQREIAYIGSRSQKPSSWILALD 302

Query: 325 LLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVML 368
           LLA+G++N   +IT +  GL++     AFE     A   +KV++
Sbjct: 303 LLANGKINTDKMIT-KVYGLDD--WREAFEA--VMAGNEIKVLV 341

ref|ZP_00193847.1| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Mesorhizobium sp. BNC1]
(344 aa)

Score: 139 bits (349), Expect: 1.92386e-31
Length: 348, Idn/Pos/Gap = 109/168/25 (31%/48%/7%)

Query:  26 VLVRPRELRVMLRSVPAP--APGEVRLQMRCVGICGSDVHYW----WHGSCGPFRLHDPM  79
           V  +P E   M R VP P   P +V +++R   ICG+DVH W    W     P     P+
Sbjct:   9 VKAKPEEGLWMER-VPLPEIGPNDVLIKVRKAAICGTDVHIWNWDEWARKTVPV----PL  63

Query:  80 IIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVD 139
           + GHE  G V  +G+ VT  ++G RV+ E  + C  C+ CR GR +LC N          
Sbjct:  64 VTGHEFVGEVVDVGSAVTEYRIGQRVSGEGHIVCGHCRNCRAGRGHLCRNTLGVGVHR-P 122

Query: 140 GSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGL 199
           G+ A Y+  P      +P+ V  E  A+ +PL  AVH    +   +G  VLV GAGPIG+
Sbjct: 123 GAFAEYISLPQHNVVAIPDDVPDEIAAIFDPLGNAVH-TALSFDLVGEDVLVTGAGPIGI 181

Query: 200 LNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQA 259
           +  +VA+  GA  +V+TDI+  RLA A+   G   V+N R+    D    V + L   + 
Sbjct: 182 MGALVAQCVGARKVVITDINPGRLALAKK-LGVRHVVNAREEKLTD----VMRKLGMTEG 236

Query: 260 -DIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVF--RYS 316
            D+ L+ +G  S  R  + V+  GG+I ++G+  +   +       + + + G++     
Sbjct: 237 FDVGLEMSGSASAFRDMIDVMNNGGKIAILGIAPTGFEIDWNKVIFKMLHLKGIYGREMF 296

Query: 317 NTYPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAV 364
            T+   IAL+  G +++  LITHR   +        F   R+   G V
Sbjct: 297 ETWYKMIALV-QGPLDISGLITHR---ISADDYREGFAAMRSGEAGKV 340

ref|NP_472141.1| hypothetical protein lin2812 [Listeria innocua Clip11262]
emb|CAC98038.1| lin2812 [Listeria innocua]
pir||AF1783 polyol dehydrogenase homolog lin2812 [imported] - Listeria innocua (strain Clip11262)
(343 aa)

Score: 138 bits (348), Expect: 2.25436e-31
Length: 343, Idn/Pos/Gap = 115/170/28 (33%/49%/8%)

Query:  37 LRSVPAPA--PGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGA  94
           LR V  P     +V++++   GICGSD+H +      P     P+ +GHE +GVV  +G 
Sbjct:  16 LRDVEEPQVYGDKVKIKVAFTGICGSDIHTFKGEYKNP---TTPVTLGHEFSGVVVEVGP  72

Query:  95 GVTSLQVGDRVALEPGV-PCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWC 153
            VTS++VGDRV  E     C +C  C+E  YNLC N +   T   +GS A +V      C
Sbjct:  73 DVTSIKVGDRVTSETTFETCGECIYCKERDYNLCSNRRGIGT-QANGSFAEFVLSREESC 131

Query: 154 YRLPESVSLEEGAMCEPLSVAVHANRRAGTTI-GSLVLVLGAGPIGLLNCMVAKAFGASI 212
           + L E +SLE  A+ EPL+  VH+     T      VLV G GPIGLL   V KA GA++
Sbjct: 132 HVLDERISLEAAALTEPLACCVHSALEKTTICPDDTVLVFGPGPIGLLLAQVVKAQGATV 191

Query: 213 I---VVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLE 269
           I   +  D D  RLA      G D +++T    + D A VV    DG  A+   DC+G  
Sbjct: 192 IMAGITKDSDRLRLA---KELGMDRIVDTL---KEDLAEVVLGMTDGYGAERVFDCSGAV 245

Query: 270 STMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASS---REIDIFGV-FRYSNTYPTCIAL 325
             +   + + +  G    VG+ +   +   +D  S   REI   G   +  +++   + L
Sbjct: 246 PAVNQGLPLTKKKGDFIQVGLFAEKKNA--IDEESIIQREIAYIGSRSQKPSSWILALDL 303

Query: 326 LASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVML 368
           LA+G++N   +IT +  GL++     AFE     A   +KV++
Sbjct: 304 LANGKINTDKMIT-KVYGLDD--WREAFEA--VMAGNEIKVLV 341

sp|P39400|YJJN_ECOLI Hypothetical zinc-type alcohol dehydrogenase-like protein yjjN
(337 aa)

Score: 138 bits (348), Expect: 2.38995e-31
Length: 318, Idn/Pos/Gap = 98/151/19 (30%/47%/5%)

Query:  29 RPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGV  88
           +P+EL    R +P P   E  ++++ VGICG+D+H W  G   PF  + P ++GHE  G 
Sbjct:   8 QPKELVWKQREIPIPGDNEALIKIKSVGICGTDIHAW--GGNQPFFSY-PRVLGHEICGE  64

Query:  89 VEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCH 148
           +  LG  +  L+ G +VA+ P V C QC  C+ GR N C  I        DG  + Y+  
Sbjct:  65 IVGLGKNIADLKNGQQVAVIPYVACQQCPACKSGRTNCCEKISVIGVHQ-DGGFSEYLSV 123

Query: 149 PAAWCYRLP-ESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKA 207
           P A    LP + +  +  A+ EP +++ HA RRA    G  VLV+GAGPIGL    +AKA
Sbjct: 124 PVANI--LPADGIDPQAAALIEPFAISAHAVRRAAIAPGEQVLVVGAGPIGLGAAAIAKA 181

Query: 208 FGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAG 267
            GA ++V      RR      H      +   D    D    ++    G+ A   +D  G
Sbjct: 182 DGAQVVVADTSPARR-----EHVATRLELPLLDPSAEDFDAQLRAQFGGSLAQKVIDATG 236

Query: 268 LESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIA--- 324
            +  M   ++++R GG +  VG+    +     +   +E  + G     N  P   A   
Sbjct: 237 NQHAMNNTVNLIRHGGTVVFVGLFKGELQFSDPEFHKKETTMMGS---RNATPEDFAKVG 293

Query: 325 -LLASGRVNVKPLITHRF 341
            L+A G++    ++THR+
Sbjct: 294 RLMAEGKITADMMLTHRY 311

ref|ZP_00230076.1| alcohol dehydrogenase, zinc-dependent [Listeria monocytogenes str. 4b H7858]
gb|EAL10006.1| alcohol dehydrogenase, zinc-dependent [Listeria monocytogenes str. 4b H7858]
(330 aa)

Score: 138 bits (348), Expect: 2.45053e-31
Length: 344, Idn/Pos/Gap = 117/172/30 (34%/50%/8%)

Query:  37 LRSVPAPA--PGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGA  94
           LR V  P     +V++++   GICGSD+H +      P     P+ +GHE +GVV  +G 
Sbjct:   3 LRDVEEPQVYGDKVKIKVAFTGICGSDIHTFKGEYKNP---TTPVTLGHEFSGVVVEVGP  59

Query:  95 GVTSLQVGDRVALEPGV-PCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWC 153
            VTS++VGDRV  E     C +C  C+E  YNLC N +   T   +GS A +V      C
Sbjct:  60 DVTSIKVGDRVTSETTFETCGECIYCKERDYNLCSNRRGIGT-QANGSFAEFVLSREESC 118

Query: 154 YRLPESVSLEEGAMCEPLSVAVHANRRAGTTI--GSLVLVLGAGPIGLLNCMVAKAFGAS 211
           + L E +SLE  A+ EPL+  VH+     TTI     VLV G GPIGLL   V KA GA+
Sbjct: 119 HVLDERISLEAAALTEPLACCVHSALEK-TTIRPDDTVLVFGPGPIGLLLAQVVKAQGAT 177

Query: 212 II---VVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGL 268
           +I   +  D D  RLA      G D +++T    + D A VV    DG  A+   DC+G 
Sbjct: 178 VIMAGITKDSDRLRLA---KELGMDRIVDTL---KEDLAEVVLGMTDGYGAERVFDCSGA 231

Query: 269 ESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASS---REIDIFGV-FRYSNTYPTCIA 324
              +   + + +  G    VG+ +   +   +D  S   REI   G   +  +++   + 
Sbjct: 232 VPAVNQGLPLTKKKGDFVQVGLFAEKKNA--IDEESIIQREIAYIGSRSQKPSSWILALD 289

Query: 325 LLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVML 368
           LLA+G++N   +IT +  GL++     AFE     A   +KV++
Sbjct: 290 LLANGKINTDKMIT-KVYGLDD--WREAFEA--VMAGNEIKVLV 328

ref|NP_418778.1| putative dehydrogenase, NAD(P)-binding [Escherichia coli K12]
gb|AAC77314.1| putative oxidoreductase; putative dehydrogenase, NAD(P)-binding [Escherichia coli K12]
gb|AAA97256.1| ORF_o345 [Escherichia coli]
pir||S56585 L-iditol 2-dehydrogenase (EC 1.1.1.14) homolog yjjN - Escherichia coli (strain K-12)
(345 aa)

Score: 138 bits (347), Expect: 2.68609e-31
Length: 318, Idn/Pos/Gap = 98/151/19 (30%/47%/5%)

Query:  29 RPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGV  88
           +P+EL    R +P P   E  ++++ VGICG+D+H W  G   PF  + P ++GHE  G 
Sbjct:  16 QPKELVWKQREIPIPGDNEALIKIKSVGICGTDIHAW--GGNQPFFSY-PRVLGHEICGE  72

Query:  89 VEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCH 148
           +  LG  +  L+ G +VA+ P V C QC  C+ GR N C  I        DG  + Y+  
Sbjct:  73 IVGLGKNIADLKNGQQVAVIPYVACQQCPACKSGRTNCCEKISVIGVHQ-DGGFSEYLSV 131

Query: 149 PAAWCYRLP-ESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKA 207
           P A    LP + +  +  A+ EP +++ HA RRA    G  VLV+GAGPIGL    +AKA
Sbjct: 132 PVANI--LPADGIDPQAAALIEPFAISAHAVRRAAIAPGEQVLVVGAGPIGLGAAAIAKA 189

Query: 208 FGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAG 267
            GA ++V      RR      H      +   D    D    ++    G+ A   +D  G
Sbjct: 190 DGAQVVVADTSPARR-----EHVATRLELPLLDPSAEDFDAQLRAQFGGSLAQKVIDATG 244

Query: 268 LESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIA--- 324
            +  M   ++++R GG +  VG+    +     +   +E  + G     N  P   A   
Sbjct: 245 NQHAMNNTVNLIRHGGTVVFVGLFKGELQFSDPEFHKKETTMMGS---RNATPEDFAKVG 301

Query: 325 -LLASGRVNVKPLITHRF 341
            L+A G++    ++THR+
Sbjct: 302 RLMAEGKITADMMLTHRY 319

gb|AAG59541.1| putative oxidoreductase [Escherichia coli O157:H7 EDL933]
dbj|BAB38741.1| putative oxidoreductase [Escherichia coli O157:H7]
ref|NP_313345.1| putative oxidoreductase [Escherichia coli O157:H7]
pir||A86135 probable oxidoreductase yjjN [imported] - Escherichia coli  (strain O157:H7, substrain EDL933)
pir||F91293 probable oxidoreductase ECs5318 [imported] - Escherichia coli (strain O157:H7, substrain RIMD 0509952)
ref|NP_290974.1| putative oxidoreductase [Escherichia coli O157:H7 EDL933]
(345 aa)

Score: 138 bits (347), Expect: 3.04421e-31
Length: 318, Idn/Pos/Gap = 98/151/19 (30%/47%/5%)

Query:  29 RPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGV  88
           +P+EL    R +P P   E  ++++ VGICG+D+H W  G   PF  + P ++GHE  G 
Sbjct:  16 QPKELVWKQREIPIPGDNEALIKIKSVGICGTDIHAW--GGNQPFFSY-PRVLGHEICGE  72

Query:  89 VEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCH 148
           +  LG  +  L+ G +VA+ P V C QC  C+ GR N C  I        DG  + Y+  
Sbjct:  73 IVGLGKNIADLKNGQQVAVIPYVACQQCPACKSGRTNCCEKISVIGVHQ-DGGFSEYLSV 131

Query: 149 PAAWCYRLP-ESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKA 207
           P A    LP + +  +  A+ EP +++ HA RRA    G  VLV+GAGPIGL    +AKA
Sbjct: 132 PVANI--LPADGIDPQAAALIEPFAISAHAVRRAAIAPGEQVLVVGAGPIGLGAAAIAKA 189

Query: 208 FGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAG 267
            GA ++V      RR      H      +   D    D    ++    G+ A   +D  G
Sbjct: 190 DGAQVVVADTSPARR-----EHVATRLELPVLDPSAEDFDAQLRAQFGGSLAQKVIDATG 244

Query: 268 LESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIA--- 324
            +  M   ++++R GG +  VG+    +     +   +E  + G     N  P   A   
Sbjct: 245 NQHAMNNTVNLIRHGGTVVFVGLFKGELQFSDPEFHKKETTMMGS---RNATPEDFAKVG 301

Query: 325 -LLASGRVNVKPLITHRF 341
            L+A G++    ++THR+
Sbjct: 302 RLMAEGKITAGMMLTHRY 319

ref|NP_755623.1| Hypothetical zinc-type alcohol dehydrogenase-like protein yjjN [Escherichia coli CFT073]
gb|AAN82196.1| Hypothetical zinc-type alcohol dehydrogenase-like protein yjjN [Escherichia coli CFT073]
(338 aa)

Score: 138 bits (347), Expect: 3.33683e-31
Length: 262, Idn/Pos/Gap = 84/136/9 (32%/51%/3%)

Query:  29 RPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGV  88
           +P  +  + + +P PA  EV L+++ VGICG+D+H +      PF  + P ++GHE    
Sbjct:   8 QPGVMEYVEKDIPTPADNEVLLKIKAVGICGTDIHAF--AGRQPFFSY-PRVLGHEICAE  64

Query:  89 VEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCH 148
             + G+   + Q+G R ++ P +PC +C  CRE + N C  +  +     DG  + Y+  
Sbjct:  65 AVSRGSQCQTAQLGQRYSVIPCIPCGECAACREEKTNCCERVSLYGVHQ-DGGFSEYLAV 123

Query: 149 PAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAF 208
                  LP+ VS   GA+ E  ++  HA RRA       VLV+GAGPIGL    +A+A 
Sbjct: 124 REDNLVPLPDEVSDSAGALVECFAIGAHAVRRAEIKAEQNVLVIGAGPIGLATAAIARAK 183

Query: 209 GASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGL 268
           GA  +VV DID +R      H      IN  +  + D    +++A  G  A + LD  G 
Sbjct: 184 GAH-VVVADIDCQR----RQHVVDHLAINAFNPTQEDFIAALREAFGGELACVVLDATGN 238

Query: 269 ESTMRLAMHVVRPGGRICLVGM 290
           +++M   ++++R GG+I  +G+
Sbjct: 239 KASMSHDVNLIRHGGKIVFIGL 260

emb|CAI78859.1| 6-hydroxycylohex-1-ene-1-carboxyl-CoA dehydrogenase [uncultured bacterium]
(340 aa)

Score: 137 bits (346), Expect: 3.47899e-31
Length: 321, Idn/Pos/Gap = 106/165/14 (33%/51%/4%)

Query:  40 VPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSL  99
           VP     ++ +++   G+C +D+HY  HG   P     P+++GHE++G+VE  GA VT++
Sbjct:  20 VPQIKGDQILVKVAACGVCHTDLHYIEHGV--PTFKKPPIVLGHEASGIVEKAGANVTNV  77

Query: 100 QVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPES 159
           + G RV +   + C  C  CR+GR N+C N+        DG+ A YV  PA     LPE+
Sbjct:  78 KPGQRVLIPAVLTCGHCPACRQGRENICSNMTMLGN-HFDGAYAEYVAVPAKDVLGLPEA 136

Query: 160 VSLEEGA-MCEPLSVAVHA-NRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTD 217
           + L+E + + + +S   HA   RA    G  V+V G G +G+    +A A G  +I V D
Sbjct: 137 IPLQEASIIADAISTPYHAVKNRAQVKPGDTVVVFGCGGVGINAVQMASAAGGYVIAV-D 195

Query: 218 IDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMH 277
           I+ R+L +A     A  V    D  + D      + L G  ADIA++  G   T+  A  
Sbjct: 196 INPRKLEWAREFGAAKTV----DASKVDRVSKEIKKLTGGGADIAMEVIGNPRTIEQAFE 251

Query: 278 VVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNT-YPTCIALLASGRVNVKPL 336
            VR GGR+C+VG    A+ +       +E++I G        Y   I ++  G++++K  
Sbjct: 252 CVRVGGRLCVVGYTHEAISIVAGKIMFKELEIVGSLGCRPVDYVPLIRMVEQGKIDLKRQ 311

Query: 337 ITHRFMGLEESSLEAAFETAR 357
           +THRF GL+E  L  AFE  +
Sbjct: 312 VTHRF-GLDE--LGQAFEVMK 329

ref|YP_000786.1| zinc binding dehydrogenase [Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130]
ref|NP_713534.1| probable Zinc-binding dehydrogenases [Leptospira interrogans serovar Lai str. 56601]
gb|AAN50552.1| probable Zinc-binding dehydrogenases [Leptospira interrogans serovar lai str. 56601]
gb|AAS69423.1| zinc binding dehydrogenase [Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130]
(348 aa)

Score: 137 bits (346), Expect: 3.56717e-31
Length: 307, Idn/Pos/Gap = 95/155/18 (30%/50%/5%)

Query:  39 SVPAPAPGEVRLQMRCVGICGSDVHYWWHGS--CGPFRLHDPMIIGHESAGVVEALGAGV  96
           SVP     +V+++++  GICGSDVH   HG+  C     H P + GHES+G++E +G  V
Sbjct:  24 SVPQLRAEQVKVRIKACGICGSDVHLVVHGTLKCK----HFPRVPGHESSGIIEEVGENV  79

Query:  97 TSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRL 156
              + GDRV +  G  C  C  C+EG+ NLC ++  F     DGS A +      + Y L
Sbjct:  80 RRFRKGDRVVIAAGTSCGVCSYCKEGKENLCKDLGVFGFDR-DGSFAEFNIVEERYLYSL 138

Query: 157 PESVSLEEGA-MCEPLSVAVHANRRAGTTIGS-LVLVLGAGPIGLLNCMVAKAFGASIIV 214
           P+ +  ++GA + + +S   HA R  G    S  V + G G +G+    +A+A     ++
Sbjct: 139 PDEIPFDQGAILADAVSTPYHAIRYRGNIQESDTVAIFGCGGLGIHAVAIARAMTKGKVI 198

Query: 215 VTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRL 274
             D+D   L  A T  GAD V+N +++   ++  V+++   G   D+  D +G  S +  
Sbjct: 199 ALDVDSGALENA-TKYGADEVVNLKEV--RNSGKVLKEVSKG--VDLLADFSGYMSNVED 253

Query: 275 AMHVVRPGGRICLVGMGSSAM--HVPLVDASSREIDIFGVFRYS-NTYPTCIALLASGRV 331
           ++  + PGGRI LVG+G   +   +P +    + I + G +       P  I L   G++
Sbjct: 254 SIRAMNPGGRIVLVGIGRQPLKFQIPFI-LIEKMISVSGSYGSDRRAIPELIELYLKGKI 312

Query: 332 NVKPLIT 338
           N+   IT
Sbjct: 313 NLSHSIT 319

gb|AAQ12031.1| putative zinc-containing alcohol dehydrogenase [Mycobacterium sp. S65]
(341 aa)

Score: 137 bits (346), Expect: 4.25031e-31
Length: 332, Idn/Pos/Gap = 102/161/16 (30%/48%/4%)

Query:  41 PAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQ 100
           PAP PGEV +++   G+CG+D+H +     GP     P+++GHE +G +  +GAG+   +
Sbjct:  20 PAPQPGEVIIEVAATGLCGTDLHEY---VAGPTFSQPPVVLGHEVSGRIVEVGAGIDRCR  76

Query: 101 VGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPESV 160
           +G+  A+ P   C  C  C    Y+LC    +      +G LA +V  P+    R+P++V
Sbjct:  77 IGEGAAVIPMDFCGSCHYCHRSLYHLCQRPGWIGLTR-NGGLASHVAVPSRLAVRVPDAV 135

Query: 161 SLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDD 220
            L+E A+ EP +VA HA RRA   +G  VLVLGAG +GL     A+A GA+ I VT+   
Sbjct: 136 DLQEAALTEPTAVAFHAVRRAELLLGETVLVLGAGALGLTVIQCARAAGAARIYVTEPSR 195

Query: 221 RRLAFAETHAGADAVINTRDLDEHDAALVVQ--QALDGAQADIALDCAGLESTMRLAMHV 278
            R   A    GA  V     LD H+     +  +   G   D+    AG        +  
Sbjct: 196 VRGNLARD-LGATLV-----LDPHEPGTTARILEETRGVGVDVVFHVAGSVEAFTQGLDC 249

Query: 279 VRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYS--NTYPTCIALLASGRVNVKPL 336
           +R  GR   +   +    + +     +E  +  VF Y   + +P  +AL+A G++ + P 
Sbjct: 250 LRKQGRFMEMSSWAGPASLDVNRHLLKETQLRMVFGYDMFDDFPAVLALMADGKIALTPQ 309

Query: 337 ITHRFMGLEESSLEAAFETARTAANGAVKVML 368
           IT R     +S++E        A  G +KV++
Sbjct: 310 ITTRIP--LDSAVEEGLNGLLEAREGLIKVLV 339

ref|NP_108423.1| threonine dehydrogenase [Mesorhizobium loti MAFF303099]
sp|Q983J7|TDH_RHILO L-threonine 3-dehydrogenase
dbj|BAB53884.1| threonine dehydrogenase [Mesorhizobium loti MAFF303099]
(344 aa)

Score: 137 bits (345), Expect: 4.77696e-31
Length: 354, Idn/Pos/Gap = 107/173/25 (30%/48%/7%)

Query:  21 ANPCGVLVRPR-ELRVMLRSVPAP--APGEVRLQMRCVGICGSDVHYW----WHGSCGPF  73
           +N    LV+ + E  + +  VP P   P +V +++R   ICG+DVH +    W     P 
Sbjct:   2 SNMMKALVKAKAEPGIWMEEVPVPEIGPNDVLIKIRKTAICGTDVHIYNWDQWAQKTVPV  61

Query:  74 RLHDPMIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPN-IKF 132
               PM+ GHE  G V   GA VT  +VG RV+ E  + C  C+ CR GR +LC N +  
Sbjct:  62 ----PMVTGHEFVGTVADFGAAVTEYKVGQRVSGEGHIVCGHCRNCRAGRGHLCRNTLGV 117

Query: 133 FATPPVDGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVL 192
               P  G+   Y+  P      +P+ V  E  A+ +PL  AVH    +   +G  VLV 
Sbjct: 118 GVNRP--GAFGEYLAIPQHNVVPIPDDVPDEIAAIFDPLGNAVH-TALSFDLVGEDVLVT 174

Query: 193 GAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQ 252
           GAGPIG++  +VA+  GA  +V+TDI+  RLA A+   G   V++       D   V+  
Sbjct: 175 GAGPIGIMGALVAQCVGARKVVITDINPVRLALAKK-LGVQHVVDASKEKLRDVMPVLGM 233

Query: 253 ALDGAQADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGV 312
                  D+ L+ +G     R  +  +  GG+I ++G+  +   +       + + + G+
Sbjct: 234 T---EGFDVGLEMSGAAPAFRDMIDTMNNGGKIAILGIAPTGFEIDWNKVIFKMLHLKGI 290

Query: 313 F--RYSNTYPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAV 364
           +      T+   IAL+  G ++V  LITHR +G+++   +  F+  R+ ++G V
Sbjct: 291 YGREMFETWYKMIALV-QGPLDVSGLITHR-IGIDD--FQEGFDAMRSGSSGKV 340

ref|YP_110030.1| threonine 3-dehydrogenase [Burkholderia pseudomallei K96243]
emb|CAH37449.1| threonine 3-dehydrogenase [Burkholderia pseudomallei K96243]
ref|YP_104863.1| threonine 3-dehydrogenase [Burkholderia mallei ATCC 23344]
gb|AAU45574.1| threonine 3-dehydrogenase [Burkholderia mallei ATCC 23344]
(343 aa)

Score: 137 bits (345), Expect: 4.93908e-31
Length: 304, Idn/Pos/Gap = 90/153/11 (29%/50%/3%)

Query:  41 PAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQ 100
           P     +V +++R   ICG+D+H W         +  PM +GHE  G +  +G  V    
Sbjct:  21 PEVGHNDVLIKIRRTAICGTDIHIWKWDDWAQKTIPVPMHVGHEYVGEIVEMGQEVRGFS  80

Query: 101 VGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPESV 160
           +GDRV+ E  + C  C+ CR GR +LC N         +G+ A Y+  PA   +++P  +
Sbjct:  81 IGDRVSGEGHITCGFCRNCRAGRRHLCRNTVGVGVNR-EGAFAEYLAIPAFNAFKIPPEI 139

Query: 161 SLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDD 220
           S +  A+ +P   A H    +   +G  VL+ GAGPIG++   +AK  GA  +V+TDI+D
Sbjct: 140 SDDLAAIFDPFGNATH-TALSFNLVGEDVLITGAGPIGVMAVAIAKHVGARNVVITDIND 198

Query: 221 RRLAFAETHAGADAVINTRD-LDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVV 279
            RL  A       AV  +R+ L +  A L + +       D+ L+ +G+ S     +  +
Sbjct: 199 YRLELARKMGATRAVNVSRESLRDVMADLHMTEGF-----DVGLEMSGVPSAFTSLLESM 253

Query: 280 RPGGRICLVGMGSSAMHVPLVDASSREIDIFGVF--RYSNTYPTCIALLASGRVNVKPLI 337
             GG++ L+G+  +   +       + ++I G++      T+   +A+L SG +++ P+I
Sbjct: 254 NHGGKVALLGIPPAQTAIDWNQVIFKGLEIKGIYGREMFETWYKMVAMLQSG-LDLSPII 312

Query: 338 THRF 341
           THRF
Sbjct: 313 THRF 316

ref|ZP_00306568.1| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Ferroplasma acidarmanus]
(333 aa)

Score: 137 bits (345), Expect: 5.14949e-31
Length: 309, Idn/Pos/Gap = 86/141/15 (27%/45%/4%)

Query:  26 VLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHES  85
           VL  P  L ++      P  GEV+++ R  GICG+D H +   +     +  P+I GHE 
Sbjct:   5 VLKEPGVLELINTEARKPDTGEVQIKTRACGICGTDFHAY---NGKHLAVKYPVIPGHEF  61

Query:  86 AGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARY 145
           +GV+ ++G GV S   GDRV ++P + C QC+ C+ G+ N C NIK        G    Y
Sbjct:  62 SGVITSIGEGVKSFMPGDRVVVDPNITCGQCEYCKGGKENFCENIKTVGI-NYPGGYGEY 120

Query: 146 VCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVA 205
           V  P    Y++P+++S E  A+ EP++  +HA       +G   ++ G G IGL    + 
Sbjct: 121 VTVPEKVVYKIPDTMSFEAAAIVEPVACIIHAFDNTHVPLGGSAIISGTGFIGLAFLQIL 180

Query: 206 KAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDC 265
           K  G   +   D +  R   A+ +          DL E D            +A++ ++ 
Sbjct: 181 KGMGYYPVYTMDTNPTRNLLAKKYGSDKIYTGIDDLMESDII---------GKANVVVEA 231

Query: 266 AGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDAS--SREIDIFGVFRYSNTYPTCI 323
            G  S +   + +  P G+I    +      + +      S+EI IFG F    T    I
Sbjct: 232 TGSNSILSKTIDMASPSGKIFAFSVYPPGEKIEIESNKIYSKEISIFGDFVNPYTMRKAI 291

Query: 324 ALLASGRVN 332
            +++SG ++
Sbjct: 292 NMISSGLID 300

ref|NP_801019.1| threonine 3-dehydrogenase [Vibrio parahaemolyticus RIMD 2210633]
dbj|BAC62852.1| threonine 3-dehydrogenase [Vibrio parahaemolyticus RIMD 2210633]
sp|P59410|TDH_VIBPA L-threonine 3-dehydrogenase
(343 aa)

Score: 137 bits (345), Expect: 5.41385e-31
Length: 331, Idn/Pos/Gap = 94/164/22 (28%/49%/6%)

Query:  41 PAPAPGEVRLQMRCVGICGSDVHYW----WHGSCGPFRLHDPMIIGHESAGVVEALGAGV  96
           P     ++ ++++   ICG+DVH +    W     P     PM++GHE  G V A+G  V
Sbjct:  23 PEVGHNDILIKIKKTAICGTDVHIYNWDEWSQKTIPV----PMVVGHEYVGEVVAIGQEV  78

Query:  97 TSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRL 156
              ++GDRV+ E  + C  C+ CR GR +LC N         +G+ A Y+  PA   +++
Sbjct:  79 RGFEIGDRVSGEGHITCGHCRNCRGGRTHLCRNTIGVGVNR-EGAFAEYLVIPAFNAFKI 137

Query: 157 PESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVT 216
           P+ +S +  ++ +P   AVH    +   +G  VL+ GAGPIG++   VAK  GA  +V+T
Sbjct: 138 PDEISDDLASIFDPFGNAVH-TALSFDLVGEDVLITGAGPIGIMAAAVAKHVGARHVVIT 196

Query: 217 DIDDRRLAFAETHAGADAV-INTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLA 275
           D+++ RL  A       AV +    L++  A L + +       D+ L+ +G  +     
Sbjct: 197 DVNEYRLELARKMGVTRAVNVAEEKLEDVMAELGMTEGF-----DVGLEMSGNPAAFNSM 251

Query: 276 MHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVF--RYSNTYPTCIALLASGRVNV 333
           +  +  GGRI L+G+  S M +       + + I G++      T+    +L+ SG +++
Sbjct: 252 LTTMNHGGRIALLGIPPSDMGIDWNQVIFKGLVIKGIYGREMFETWYKMASLIQSG-LDL 310

Query: 334 KPLITHRFMGLEESSLEAAFETARTAANGAV 364
            P+ITH +   +    +  F+  R+  +G V
Sbjct: 311 SPIITHHY---KIDDFQEGFDVMRSGMSGKV 338

gb|AAO08354.1| Threonine dehydrogenase [Vibrio vulnificus CMCP6]
ref|NP_763364.1| Threonine dehydrogenase [Vibrio vulnificus CMCP6]
sp|Q8D442|TDH_VIBVU L-threonine 3-dehydrogenase
(343 aa)

Score: 137 bits (344), Expect: 6.13565e-31
Length: 346, Idn/Pos/Gap = 99/170/25 (28%/49%/7%)

Query:  28 VRPRELRVMLRSVPAPAPG--EVRLQMRCVGICGSDVHYW----WHGSCGPFRLHDPMII  81
           ++P E  + +  V  P  G  ++ ++++   ICG+DVH +    W     P     PM++
Sbjct:   9 LKPEE-GIWMTEVDKPVLGHNDLLIKIKKTAICGTDVHIYNWDEWSQKTIPV----PMVV  63

Query:  82 GHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGS 141
           GHE  G V  +G  V   ++GDRV+ E  + C  C+ CR GR +LC N          G 
Sbjct:  64 GHEYVGEVVGIGQEVRGFEIGDRVSGEGHITCGHCRNCRGGRTHLCRNTIGVGVNRT-GC 122

Query: 142 LARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLN 201
            + Y+  PA   +++P ++S +  ++ +P   AVH    +   +G  VL+ GAGPIG++ 
Sbjct: 123 FSEYLVIPAFNAFKIPANISDDLASIFDPFGNAVH-TALSFDLVGEDVLITGAGPIGIMA 181

Query: 202 CMVAKAFGASIIVVTDIDDRRLAFAETHAGADAV-INTRDLDEHDAALVVQQALDGAQAD 260
             VAK  GA  +V+TD+++ RL  A       AV +  + LD+  A L + +       D
Sbjct: 182 AAVAKHVGARHVVITDVNEYRLDLARKMGVTRAVNVAEQKLDDVMAELGMTEGF-----D 236

Query: 261 IALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVF--RYSNT 318
           + L+ +G  S     +  +  GGRI L+G+  S M +       + + I G++      T
Sbjct: 237 VGLEMSGNPSAFNSMLKTMNHGGRIALLGIPPSDMGIDWNQVIFKGLVIKGIYGREMFET 296

Query: 319 YPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAV 364
           +    +L+ SG +++ P+ITH F   +    +  F+  R+  +G V
Sbjct: 297 WYKMASLIQSG-LDLTPIITHHF---KVDDFQQGFDIMRSGMSGKV 338

ref|NP_979550.1| sorbitol dehydrogenase [Bacillus cereus ATCC 10987]
gb|AAS42158.1| sorbitol dehydrogenase [Bacillus cereus ATCC 10987]
(340 aa)

Score: 137 bits (344), Expect: 6.78179e-31
Length: 320, Idn/Pos/Gap = 100/168/30 (31%/52%/9%)

Query:  31 RELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVE  90
           R++R+  R      P +V++++   GICGSD+H + H    P  ++   ++GHE +G + 
Sbjct:  10 RDIRIEERETKELQPNDVKVKVAWAGICGSDLHAYLHPGSVPINMN--TVMGHEFSGEIA  67

Query:  91 ALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFAT-----PPVDGSLARY 145
            +G+ VT  + GDRV + P +  L+     E        I+ F T       +DG  A Y
Sbjct:  68 EVGSHVTKFKKGDRVCIYPMM--LKDPSNAE--------IERFITLDAVGAQIDGGFAEY 117

Query: 146 VCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVA 205
           V  P    +++P+ + LE  AM EP +V+  + + +    G  V+V GAGPIGL   + A
Sbjct: 118 VILPQKTIFKIPDHLPLELAAMVEPAAVSFQSIKDSNVREGDTVVVYGAGPIGLFAVLGA 177

Query: 206 KAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDC 265
           KA GAS I+V D+ D RL  A T  GA  V N ++++  +    +++   G  AD+A++ 
Sbjct: 178 KAAGASNIIVIDLFDSRLDKA-TEMGATHVFNAKEVNPVEE---IRKLFPGG-ADVAIEA 232

Query: 266 AGLESTMRLAMHVVRPGGRICLVGMGSSAM--HVP--LVDASSREIDIFGVFRYSN-TYP 320
           AG+EST   A+   +  G + ++   +  +  +VP  L+ + ++   + G   YSN TY 
Sbjct: 233 AGVESTFNQAIQSTKVRGTMMVISFHTQDIQFNVPASLIFSGAK---LMGSVGYSNETYN 289

Query: 321 TCIALLASGRVNVKPLITHR 340
             I L A+GR+  + +IT +
Sbjct: 290 EVIELFANGRLPAQSIITSK 309

ref|YP_052467.1| putative zinc-binding dehydrogenase [Erwinia carotovora subsp. atroseptica SCRI1043]
emb|CAG77278.1| putative zinc-binding dehydrogenase [Erwinia carotovora subsp. atroseptica SCRI1043]
(340 aa)

Score: 137 bits (344), Expect: 7.37193e-31
Length: 316, Idn/Pos/Gap = 94/143/17 (29%/45%/5%)

Query:  30 PRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVV  89
           P++L    R +P P  GE  ++++ VGICG+D+H W  G   PF    P ++GHE  G V
Sbjct:  12 PKKLVWKKREIPIPGEGEALIKIKSVGICGTDIHAW--GGNQPF-FSYPRVLGHEICGEV  68

Query:  90 EALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHP 149
              G  V   + G +V + P V C QC  C+ GR N C  I        DG  + Y+  P
Sbjct:  69 VDTGKNVDRFKKGQQVTVIPYVACQQCPACKSGRTNCCEKISVIGVHQ-DGGFSEYLAVP 127

Query: 150 AAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFG 209
                 L E +  +  A+ EP +++ HA RRA    G  VLV+GAGPIG L         
Sbjct: 128 TT-NLLLAEGIDPQAAALIEPYAISAHAVRRAKVLQGEQVLVVGAGPIG-LGAAAIAKAE 185

Query: 210 ASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLE 269
            + +VV D    R      H G   V    D    D    ++    G+ A+  +D  G +
Sbjct: 186 GAHVVVADTSAARREHVIAHLGLSVV----DPSAEDFEAQLRAEFGGSLAEKVIDATGNQ 241

Query: 270 STMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIA----L 325
             M   ++++R GG I  VG+    +     +   +E  + G     N  P   A    L
Sbjct: 242 HAMNNTINLIRHGGSIVFVGLFKGDLQFSDPEFHKKETTMMGS---RNATPEDFAKVGHL 298

Query: 326 LASGRVNVKPLITHRF 341
           ++ G++  + ++THR+
Sbjct: 299 MSEGKLTAEMMLTHRY 314

gb|EAA59908.1| hypothetical protein AN3700.2 [Aspergillus nidulans FGSC A4]
ref|XP_407837.1| hypothetical protein AN3700.2 [Aspergillus nidulans FGSC A4]
(351 aa)

Score: 136 bits (343), Expect: 7.94683e-31
Length: 291, Idn/Pos/Gap = 96/147/27 (32%/50%/9%)

Query:  22 NPCGVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMII  81
           N   V V    L +  R V  P P EV +Q+   GICGSD H W + +     +   +I+
Sbjct:   4 NNAAVRVSHLTLAIQDRPVTPPGPNEVLVQVISTGICGSDTHNWNNPN-----VSRELIL  58

Query:  82 GHESAGV---VEALGAGVTSLQVGDRVALEPGVPCL--QCQR------CREGRYNLCPNI 130
           GHESAG+   +  + + V    VG R+A+EPG  C   +C        C  G  N C N+
Sbjct:  59 GHESAGLRGLIVEIDSEVKDRHVGQRMAVEPGFACATRKCPDNQEDAFCLRGNPNTCANL 118

Query: 131 KFFATPPVDGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAG-TTIGSLV 189
           K+    P DG+L +Y    A     +PE +S EE    +PL++AV   RRA  +    +V
Sbjct: 119 KYCGLDPTDGTLQQYFTCKAHMAIPIPEEISWEEAGAIQPLAIAVQLARRAALSATAKVV 178

Query: 190 LVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAAL- 248
              G GP+GLL   +AKA+G   IVV DI+  RL FA ++ G D  + +  + E+   L 
Sbjct: 179 GDGGCGPLGLLVIAIAKAYGVCKIVVFDIEQSRLDFALSY-GEDIGVLSPKISENVEPLK 237

Query: 249 --------VVQQALDGAQADIALDCAGLESTMRLAMHVVRPGGRICLVGMG 291
                   VV++   G   DI+++ +G +S+ ++A+ +++P G     G+G
Sbjct: 238 FVFEFTSSVVREHNLGHGVDISVEASGADSSAQMALTILKPRGTCIQAGLG 288

gb|AAU23458.1| threonine 3-dehydrogenase [Bacillus licheniformis ATCC 14580]
ref|YP_091510.1| Tdh [Bacillus licheniformis ATCC 14580]
ref|YP_079096.1| threonine 3-dehydrogenase [Bacillus licheniformis ATCC 14580]
gb|AAU40817.1| Tdh [Bacillus licheniformis DSM 13]
(346 aa)

Score: 136 bits (343), Expect: 8.49538e-31
Length: 349, Idn/Pos/Gap = 101/167/14 (28%/47%/4%)

Query:  21 ANPCGVLVRPRELRVMLRSVPAPA--PGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDP  78
            N   ++ +P E       VP P     EV ++++   ICG+DVH +        R+  P
Sbjct:   3 GNMKALIKKPGEPGASFELVPIPKIDKHEVLIKVKAASICGTDVHIYNWDEWAKSRVKPP  62

Query:  79 MIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPV 138
            + GHE +G V  +G  VT+++ G+ V+ E  + C +C  C  G+ ++C           
Sbjct:  63 YVFGHEFSGEVVQVGENVTTVKEGEYVSAETHIVCGKCLPCLTGKEHVCKKTLILGV-DT 121

Query: 139 DGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIG 198
           DG  A YV  PAA  ++ P  +  +  ++ EPL  AVH     G T G  V V+G GPIG
Sbjct: 122 DGCFAEYVKMPAANIWKNPAGMPEDLASIQEPLGNAVH-TVLTGMTAGVKVAVVGCGPIG 180

Query: 199 LLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQ 258
           L+   VAKA GA+ ++  D ++ RL  A      D +     +++ D    V    +G  
Sbjct: 181 LMAVAVAKASGAAQVIAIDKNEYRLDLALQMGATDII----SVEKEDPLKNVSALTNGEG 236

Query: 259 ADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLV-DASSREIDIFGVF--RY 315
           AD+  + +G  + +R ++ +   GGR+ ++ +    + + +  D   + + + G+   + 
Sbjct: 237 ADLVCEMSGHPTAIRQSLKMAANGGRVHVLSLPEHPVCIDMTNDIVFKGLTVQGITGRKM 296

Query: 316 SNTYPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAV 364
             T+     LL SG + +KP+ITHRF  +EE   E  FE  R    G V
Sbjct: 297 FETWRQVSGLLQSGTIQIKPVITHRF-PMEE--FEKGFELMRKGQCGKV 342

ref|YP_176836.1| sorbitol dehydrogenase [Bacillus clausii KSM-K16]
dbj|BAD65875.1| sorbitol dehydrogenase [Bacillus clausii KSM-K16]
(361 aa)

Score: 135 bits (341), Expect: 1.34426e-30
Length: 347, Idn/Pos/Gap = 106/166/28 (30%/47%/8%)

Query:  37 LRSVPAPAP-----GEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEA  91
           +R   +P P      EV +++   GICGSD+  +     GP+        GHE +G +E 
Sbjct:  12 IRFEQSPKPTIMNDNEVIVRVETAGICGSDLSRY--KKLGPYI--SGTTFGHECSGTIEE  67

Query:  92 LGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFF-ATPPVDGSLARYVCHPA 150
           +G+ V+ L+ G RVA+ P +PC  C +CR+G ++ CP++    A  P  G+ A YV  PA
Sbjct:  68 VGSNVSHLKEGMRVAVCPALPCGDCTQCRQGAFSRCPSLTVIGAVQP--GAFAEYVKLPA 125

Query: 151 AWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGA 210
                LP  +  +  A  EP +V  H   +     G+ V ++G G IGLL    AK FGA
Sbjct: 126 ENVLPLPNEIDADTAAFIEPAAVVAHGFYKTAIEPGADVAIIGCGSIGLLAIQWAKLFGA 185

Query: 211 SIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLES 270
             +   DID+++L  A+   GAD  +N  D   H+    +     G   D+A++ AG   
Sbjct: 186 RYVYAIDIDEQKLKVAK-ELGADQRVNPLDGPVHEQ---IHDLTAGEGVDVAIEAAGTPI 241

Query: 271 TMRLAMHVVRPGGRICLVGM--GSSAMHVPLVDASSR-EIDIFGVFR-YSNTYP-----T 321
           T   A+ + + GG +  +G+  G   +     +   R E+ + G +   S  +P     T
Sbjct: 242 TSAQALALPKKGGEVVFLGIPYGDVTIERFYFEKIVRNELRVHGSWNGLSAPFPGKEWKT 301

Query: 322 CIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVML 368
            I  L +G + V PLITHR   L  S     F+   + + G +K +L
Sbjct: 302 AIHSLQTGALQVNPLITHR---LPLSDGPFVFKEMASGSPGYIKTLL 345

ref|ZP_00221546.1| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Burkholderia cepacia R1808]
(342 aa)

Score: 135 bits (341), Expect: 1.38988e-30
Length: 304, Idn/Pos/Gap = 88/152/11 (28%/50%/3%)

Query:  41 PAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQ 100
           P     +V +++R   ICG+D+H W         +  PM +GHE  G +  +G  V    
Sbjct:  21 PEVGHNDVLIKIRRTAICGTDIHIWKWDDWAQKTIPVPMHVGHEYVGEIVEMGQEVRGFA  80

Query: 101 VGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPESV 160
           +GDRV+ E  + C  C+ CR GR +LC N         +G+ A Y+  PA   +++P  +
Sbjct:  81 IGDRVSGEGHITCGFCRNCRAGRRHLCRNTVGVGVNR-EGAFAEYLAIPAFNAFKIPPEI 139

Query: 161 SLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDD 220
           S +  ++ +P   A H    +   +G  VL+ GAGPIG++   +AK  GA  +V+TDI+D
Sbjct: 140 SDDLASIFDPFGNATH-TALSFNLVGEDVLITGAGPIGIMAVAIAKHVGARNVVITDIND 198

Query: 221 RRLAFAETHAGADAVINTRD-LDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVV 279
            RL  A       AV   R+ L +  A L + +       D+ L+ +G+ S     +  +
Sbjct: 199 YRLELARKMGATRAVNVARESLRDVMAELRMTEGF-----DVGLEMSGVPSAFTSLLEAM 253

Query: 280 RPGGRICLVGMGSSAMHVPLVDASSREIDIFGVF--RYSNTYPTCIALLASGRVNVKPLI 337
             GG++ L+G+  +   +       + ++I G++      T+   +A+L SG +++ P++
Sbjct: 254 NHGGKVALLGIPPAQTAIDWNQVIFKGLEIKGIYGREMFETWYKMVAMLQSG-LDLSPIV 312

Query: 338 THRF 341
           THRF
Sbjct: 313 THRF 316

ref|ZP_00233076.1| alcohol dehydrogenase, zinc-dependent [Listeria monocytogenes str. 1/2a F6854]
gb|EAL07001.1| alcohol dehydrogenase, zinc-dependent [Listeria monocytogenes str. 1/2a F6854]
(343 aa)

Score: 135 bits (341), Expect: 1.68392e-30
Length: 332, Idn/Pos/Gap = 112/167/28 (33%/50%/8%)

Query:  47 EVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGDRVA 106
           +V++++   GICGSD+H +      P     P+ +GHE +GVV  +G  VTS++VGDRV 
Sbjct:  28 KVKIKVAFTGICGSDIHTFKGEYKNP---TTPVTLGHEFSGVVVEVGPDVTSIKVGDRVT  84

Query: 107 LEPGV-PCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPESVSLEEG 165
            E     C +C  C+E  YNLC N +   T   +GS A +V      C+ L E +SLE  
Sbjct:  85 SETTFETCGECIYCKEHDYNLCSNRRGIGT-QANGSFAEFVLSREESCHVLDERISLEAA 143

Query: 166 AMCEPLSVAVHANRRAGTTI--GSLVLVLGAGPIGLLNCMVAKAFGASII---VVTDIDD 220
           A+ EPL+  VH+     TTI     VLV G GPIGLL   V KA GA++I   +  D D 
Sbjct: 144 ALTEPLACCVHSALEK-TTIRPDDTVLVFGPGPIGLLLAQVVKAQGATVIMAGITKDSDR 202

Query: 221 RRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVVR 280
            RLA      G D +++T    + D A VV     G  A+   DC+G    +   + + +
Sbjct: 203 LRLA---KELGMDRIVDTL---KEDLAEVVLGMTGGYGAERVFDCSGAVPAVNQGLPLTK 256

Query: 281 PGGRICLVGMGSSAMHVPLVDASS---REIDIFGV-FRYSNTYPTCIALLASGRVNVKPL 336
             G    VG+ +   +   +D  S   REI   G   +  +++   + LLA+G++N   +
Sbjct: 257 KKGDFVQVGLFAEKKNA--IDEESIIQREIAYIGSRSQKPSSWILALDLLANGKINTDKM 314

Query: 337 ITHRFMGLEESSLEAAFETARTAANGAVKVML 368
           IT +  GL++     AFE     A   +KV++
Sbjct: 315 IT-KVYGLDD--WREAFEA--VMAGNEIKVLV 341

gb|AAP39869.1| isopropanol dehydrogenase [Phytomonas sp. ADU-2003]
(361 aa)

Score: 135 bits (340), Expect: 1.7266e-30
Length: 350, Idn/Pos/Gap = 106/173/29 (30%/49%/8%)

Query:  34 RVMLRSVPAPAP--GEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEA  91
           R++L   P P P   E  +++    ICG+D+H       G + + + + IGHE  GV+E+
Sbjct:  24 RIVLDEKPVPVPKHSEALIKITTTTICGTDIHILK----GEYPVAEGLTIGHEPIGVIES  79

Query:  92 LGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPN-----IKFFATPPVDGSLARYV 146
            G GVT  + G RV +    PC  C  C EG  + C +      KF  T  +DGS A Y+
Sbjct:  80 FGDGVTGFKKGQRVVIGAITPCSSCSSCMEGIRSQCGSKLMGGWKFGNT--IDGSQAEYL 137

Query: 147 CHP--AAWCYRLPESVSLEEGAMC-EPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCM 203
             P  AA  Y +P+ ++ E+  MC + +S        AG  +G  V++   GPIGL    
Sbjct: 138 IVPDAAANMYPIPDGITDEQVLMCPDIMSTGFSGPESAGVKVGDTVVIYAQGPIGLGATA 197

Query: 204 VAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIAL 263
            AK  GA+ ++V D    RLA A+   GAD    T D  + +    V +   G   D+A+
Sbjct: 198 GAKMMGATKVIVVDRFPERLALAKK-LGADY---TLDFTKCNPIEEVMRLTGGRGVDVAI 253

Query: 264 DCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRY-----SNT 318
           +  GL+ST    +  ++PGG +  +G+ S  + +P  DA +  +  F +           
Sbjct: 254 EALGLQSTFESCLRCLKPGGVLSSLGVYSDDLRLP-NDAFAAGLGDFKIVTTLCPGGKER 312

Query: 319 YPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVML 368
               ++++ SGRV+++P++TH F  L+E  +E A++      +G +KV +
Sbjct: 313 MRRLLSVIESGRVDMRPMVTHTFK-LDE--IEKAYDLFGNQRDGVLKVAI 359

ref|ZP_00218247.1| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Burkholderia cepacia R18194]
(342 aa)

Score: 135 bits (340), Expect: 1.86125e-30
Length: 327, Idn/Pos/Gap = 92/158/14 (28%/48%/4%)

Query:  41 PAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQ 100
           P     +V +++R   ICG+D+H W         +  PM +GHE  G +  +G  V    
Sbjct:  21 PEVGHNDVLIKIRRTAICGTDIHIWKWDDWAQKTIPVPMHVGHEYVGEIVEMGQEVRGFA  80

Query: 101 VGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPESV 160
           +GDRV+ E  + C  C+ CR GR +LC N         +G+ A Y+  PA   +++P  +
Sbjct:  81 IGDRVSGEGHITCGFCRNCRAGRRHLCRNTVGVGVNR-EGAFAEYLAIPAFNAFKIPPEI 139

Query: 161 SLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDD 220
           S +  ++ +P   A H    +   +G  VL+ GAGPIG++   +AK  GA  +V+TDI+D
Sbjct: 140 SDDLASIFDPFGNATH-TALSFNLVGEDVLITGAGPIGIMAVAIAKHVGARNVVITDIND 198

Query: 221 RRLAFAETHAGADAVINTRD-LDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVV 279
            RL  A       AV   R+ L +  + L + +       D+ L+ +G+ S     +  +
Sbjct: 199 YRLELARKMGATRAVNVARESLRDVMSDLHMTEGF-----DVGLEMSGVPSAFTSMLEAM 253

Query: 280 RPGGRICLVGMGSSAMHVPLVDASSREIDIFGVF--RYSNTYPTCIALLASGRVNVKPLI 337
             GG++ L+G+  +   +       + ++I G++      T+   +A+L SG +++ P+I
Sbjct: 254 NHGGKVALLGIPPAQTAIDWNQVIFKGLEIKGIYGREMFETWYKMVAMLQSG-LDLSPII 312

Query: 338 THRFMGLEESSLEAAFETARTAANGAV 364
           THRF        E  F    +  +G V
Sbjct: 313 THRFAA---DDYEKGFAAMLSGESGKV 336

ref|NP_936361.1| threonine dehydrogenase [Vibrio vulnificus YJ016]
dbj|BAC96331.1| threonine dehydrogenase [Vibrio vulnificus YJ016]
(343 aa)

Score: 135 bits (340), Expect: 2.04017e-30
Length: 346, Idn/Pos/Gap = 98/169/25 (28%/48%/7%)

Query:  28 VRPRELRVMLRSVPAPAPG--EVRLQMRCVGICGSDVHYW----WHGSCGPFRLHDPMII  81
           ++P E  + +  V  P  G  ++ ++++   ICG+DVH +    W     P     PM++
Sbjct:   9 LKPEE-GIWMTEVDKPVLGHNDLLIKIKKTAICGTDVHIYNWDEWSQKTIPV----PMVV  63

Query:  82 GHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGS 141
           GHE  G V  +G  V   ++GDRV+ E  + C  C+ CR GR +LC N          G 
Sbjct:  64 GHEYVGEVVGIGQEVRGFEIGDRVSGEGHITCGHCRNCRGGRTHLCRNTIGVGVNRT-GC 122

Query: 142 LARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLN 201
            + Y+  PA   +++P ++S +  ++ +P   AVH    +   +G  VL+ GAGPIG++ 
Sbjct: 123 FSEYLVIPAFNAFKIPANISDDLASIFDPFGNAVH-TALSFDLVGEDVLITGAGPIGIMA 181

Query: 202 CMVAKAFGASIIVVTDIDDRRLAFAETHAGADAV-INTRDLDEHDAALVVQQALDGAQAD 260
             VAK  GA  +V+TD+++ RL  A       AV +  + LD+    L + +       D
Sbjct: 182 AAVAKHVGARHVVITDVNEYRLDLARKMGVTRAVNVAEQKLDDVMVELGMTEGF-----D 236

Query: 261 IALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVF--RYSNT 318
           + L+ +G  S     +  +  GGRI L+G+  S M +       + + I G++      T
Sbjct: 237 VGLEMSGNPSAFNSMLKTMNHGGRIALLGIPPSDMGIDWNQVIFKGLVIKGIYGREMFET 296

Query: 319 YPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAV 364
           +    +L+ SG +++ P+ITH F   +    +  F+  R+  +G V
Sbjct: 297 WYKMASLIQSG-LDLTPIITHHF---KVDDFQQGFDIMRSGMSGKV 338

emb|CAC46156.1| PUTATIVE ZINC-CONTAINING ALCOHOL DEHYDROGENASE PROTEIN [Sinorhizobium meliloti]
ref|NP_385683.1| PUTATIVE ZINC-CONTAINING ALCOHOL DEHYDROGENASE PROTEIN [Sinorhizobium meliloti 1021]
(347 aa)

Score: 135 bits (339), Expect: 2.39064e-30
Length: 334, Idn/Pos/Gap = 98/162/15 (29%/48%/4%)

Query:  40 VPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSL  99
           +P P P ++ +++   GICG+D H       G F    P+ +GHE  G+V   G+ V  +
Sbjct:  19 IPEPGPDDLLVKVEACGICGTDRHLLH----GEFPSTPPVTLGHEFCGIVVEAGSAVRDI  74

Query: 100 QVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPES 159
             G R+  +P + C +C +C+ GR NLC N++       DG  A YV  P    + +P +
Sbjct:  75 APGARITGDPNISCGRCPQCQAGRVNLCRNLRAIGIHR-DGGFAEYVLVPRKQAFEIPLT 133

Query: 160 VSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDID 219
           +    GA CEPL+  +H    +G   GS V +LG G IGLL   +A+  GA+ ++++   
Sbjct: 134 LDPVHGAFCEPLACCLHGVDLSGIKAGSTVAILGGGVIGLLTVQLARLAGATTVILSTRQ 193

Query: 220 DRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVV 279
             +   AE   GA A ++    D  + A+     L     D+ ++CAG+  T++ +  + 
Sbjct: 194 ATKRRLAE-EVGATATVDPSAGDVVE-AIAGPVGLVPGGVDVVIECAGVAETVKQSTRLA 251

Query: 280 RPGGRICLVGMGSSAMHVPL--VDASSREIDIFGVFRYSNTYPTCIALLASGRVNVKPLI 337
           + GG + ++G+      V +   D   RE+ + G F     +     L+A+G + +  +I
Sbjct: 252 KAGGTVVILGVLPQGEKVEIEPFDILFRELRVLGSFINPFVHRRAADLVATGAIEIDRMI 311

Query: 338 THRFMGLEESSLEAAFETARTAANGAVKVMLTIP 371
           + R      S  EA    +  AA G VKV L IP
Sbjct: 312 SRRI-----SLDEAPDVISNPAAAGEVKV-LVIP 339

ref|ZP_00109233.1| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Nostoc punctiforme PCC 73102]
(349 aa)

Score: 135 bits (339), Expect: 2.6424e-30
Length: 328, Idn/Pos/Gap = 101/160/18 (30%/48%/5%)

Query:  20 KANPCGVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPM  79
           KA    +L    +LR+   + P PA GEV +Q+     CG+D+  W  G      L  P 
Sbjct:   8 KALLAALLYGQEDLRLEQVADPTPAAGEVVIQVGAATTCGTDLKVWRRGGHAKM-LKPPT  66

Query:  80 IIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVD 139
           + GHE AG + ALGAGVT+ QVGDR+      PC++C  C+   Y+LCPN+ +      +
Sbjct:  67 LFGHEGAGRIVALGAGVTNWQVGDRIVANNSAPCMKCFFCQRQEYSLCPNLTW-----NN 121

Query: 140 GSLARYVCHPAAWC----YRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAG 195
           G+ A Y+  PA        ++P+ +  E  AM EPL+  +H   R+       V+VLG G
Sbjct: 122 GTFAEYLKIPAPIVEHNLLQIPDELPWELAAMTEPLACVLHGVARSNIKPKDRVVVLGDG 181

Query: 196 PIGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALD 255
            IGL+   VA     + +++   ++ RL   +   GA    N   +   D   +V++   
Sbjct: 182 AIGLM--FVAALSEKAEVLLWGGNNHRLEIGQK-LGATQTFNYHQIP--DIPNLVKELTQ 236

Query: 256 GAQADIALDCAGLESTMRLAMHVVRPGGRICLVG--MGSSAMHVPLVDASSREIDIFGVF 313
           G  AD+A++  G+ S    A+   RPG  + L G     +++ V        E+ I GVF
Sbjct: 237 GWGADVAIEATGVPSVWETAIACARPGATVNLFGGCPRDTSITVNTEQLHYSELTIKGVF 296

Query: 314 RYSNTY-PTCIALLASGRVNVKPLITHR 340
             +  Y    +AL+AS ++  + LI+ +
Sbjct: 297 HNTPEYVREALALIASRKIPFELLISEQ 324

ref|NP_720188.1| threonine 3-dehydrogenase [Shewanella oneidensis MR-1]
gb|AAN57632.1| threonine 3-dehydrogenase [Shewanella oneidensis MR-1]
sp|Q8E8J1|TDH_SHEON L-threonine 3-dehydrogenase
(341 aa)

Score: 135 bits (339), Expect: 2.68687e-30
Length: 342, Idn/Pos/Gap = 94/166/24 (27%/48%/7%)

Query:  32 ELRVMLRSVPAPAPG--EVRLQMRCVGICGSDVHYW----WHGSCGPFRLHDPMIIGHES  85
           E  + L   P P  G  ++ ++++   ICG+D+H +    W     P     PM++GHE 
Sbjct:  10 EKGIWLVDAPKPEMGHNDLLIKIKKTAICGTDMHIYNWDEWSQKTIPV----PMVVGHEY  65

Query:  86 AGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARY 145
            G V  +G  V    +GDRV+ E  + C  C+ CR GR +LC N         +GS A Y
Sbjct:  66 VGEVVDIGQEVRGFNIGDRVSGEGHITCGHCRNCRAGRTHLCRNTSGVGVNR-EGSFAEY 124

Query: 146 VCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVA 205
           +  PA   +++P+ +S +  ++ +P   AVH    +   +G  VL+ GAGPIG++   V 
Sbjct: 125 LVIPAFNAFKIPDDISDDLASIFDPFGNAVH-TALSFDLVGEDVLITGAGPIGIMAAAVC 183

Query: 206 KAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQA-DIALD 264
           +  GA  +V+TD+++ RL  A    GA   +N    +  D    V + L   +  D+ L+
Sbjct: 184 RHVGARHVVITDVNEYRLELARK-MGATRAVNVAQENLKD----VMKELGMTEGFDVGLE 238

Query: 265 CAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVF--RYSNTYPTC 322
            +G+ S  R  +  +  GG+I ++G+    M +       + + I G++      T+   
Sbjct: 239 MSGVPSAFRAMLDTMNHGGKIAMLGIPGGEMAIDWSKVIFKGLVIKGIYGREMFETWYKM 298

Query: 323 IALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAV 364
            +L+ SG +++ P+ITH +   +    +  F+   +  +G V
Sbjct: 299 ASLIQSG-LDISPIITHHY---KIDDFQKGFDAMGSGQSGKV 336

ref|ZP_00108852.2| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Nostoc punctiforme PCC 73102]
(368 aa)

Score: 135 bits (339), Expect: 2.75497e-30
Length: 341, Idn/Pos/Gap = 106/156/25 (31%/45%/7%)

Query:  40 VPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSL  99
           VP   P EV +Q+R VG+C SD+    +    P     P I GHE+AG + A+G  V   
Sbjct:  35 VPTVEPDEVLVQVRVVGLCQSDIKKIRYPLYEP-----PRIFGHETAGTIAAIGNNVKGW  89

Query: 100 QVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATP----PVDGSLARYVCHPA----- 150
           QVG RVA+   +PC++C  C    +++C   K  +T        G  A YV  P      
Sbjct:  90 QVGQRVAVMHHIPCMRCAYCLNDNFSMCDVYKNISTTAGFNASGGGFADYVKVPGHIVEN 149

Query: 151 AWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGA 210
                +P+++S EE +  EP +  + A R+A    G  VLV GAGPIGL+  M+ K FGA
Sbjct: 150 GGLIPIPDNISFEEASFVEPTNCCLKAVRKAQIAPGQTVLVTGAGPIGLMFIMLVKYFGA 209

Query: 211 SIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLES 270
             I  TD+   R+  A +  GA+A  + RD    D    +     G   D+ L     E 
Sbjct: 210 KAI-ATDLLPSRIDKALS-VGAEAAFDARD---PDLPAKISALTGGLGVDVTLLAVPSEK 264

Query: 271 TMRLAMHVVRPGGRICLVGMGSSAMHVPLVD--ASSREIDIFGVFRYSNTYPTCIA-LLA 327
               A+   R GG+I         + +P+       REID+ G +  S       A ++ 
Sbjct: 265 AFFQALDSTRKGGKILFFAEFPDEVEIPINPNILYRREIDLIGSYSSSYRLQNLSADIVF 324

Query: 328 SGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVML 368
           + R++VK LI+ R+       L AA E A        K+++
Sbjct: 325 NQRIDVKALISDRY---PLKDLSAAVEQAIAPTPDTYKILI 362

ref|NP_681760.1| putative dehydrogenase [Thermosynechococcus elongatus BP-1]
dbj|BAC08522.1| tll0970 [Thermosynechococcus elongatus BP-1]
(373 aa)

Score: 134 bits (338), Expect: 3.3378e-30
Length: 361, Idn/Pos/Gap = 113/174/32 (31%/48%/8%)

Query:  13 AGSVLNEKANPCG------VLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWW  66
           + S  N   NP G      VL    ++R+     P P PGEV +++R    CG+D+  W 
Sbjct:  10 SASSCNGWPNPWGSAMKAAVLYGKEDVRIETVPDPTPGPGEVVIRVRAATTCGTDLKVWR  69

Query:  67 HGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNL 126
            G      L  P++ GHE+AG + ALGAGVT  QVGDRV      PC QC  C+   ++L
Sbjct:  70 RGGHARM-LTPPILFGHEAAGEIVALGAGVTGWQVGDRVVANNSAPCGQCFYCQRQAFSL 128

Query: 127 CPNIKFFATPPVDGSLARYVCHPAAWCYR----LPESVSLEEGAMCEPLSVAVHANRRAG 182
           CP+++F      +G+ A Y+  PA+   +    +PES+     A+ EPL+  +H   R+G
Sbjct: 129 CPHLEF-----NNGTFAEYLKLPASIVRQNLLPIPESLPFALAALTEPLACVLHGVARSG 183

Query: 183 TTIGSL--------VLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADA 234
                +        ++VLG G IGL+   V    GA ++      ++RLA A T  GA+ 
Sbjct: 184 FDPAMVATWPSPPQIVVLGDGAIGLMFVGVLAQQGARVLAFGG-SNQRLAIATTF-GAEQ 241

Query: 235 VINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVVRPGGRICLVG--MGS 292
            IN       D   VV+   +G  ADI ++  G+      A+   RPG  I L G     
Sbjct: 242 TINHHQCG--DIPAVVKDWTEGRGADIVIEATGVPEVWETAIACGRPGATINLFGGCPRE 299

Query: 293 SAMHVPLVDASSREIDIFGVFRYSNTY-PTCIALLASGRVNVKPLITHRFMGLE-ESSLE 350
           + + V        E+ + GVF  + ++    + L+ASG +  + LI+ +   +E E+ L+
Sbjct: 300 TTIRVDTERLHYEELTLKGVFHNTPSFVRQALQLIASGTLPFEKLISGQAPLMEIETVLQ 359

Query: 351 A 351
           A
Sbjct: 360 A 360

ref|YP_206375.1| threonine 3-dehydrogenase [Vibrio fischeri ES114]
gb|AAW87487.1| threonine 3-dehydrogenase [Vibrio fischeri ES114]
(343 aa)

Score: 134 bits (337), Expect: 4.66022e-30
Length: 346, Idn/Pos/Gap = 98/171/25 (28%/49%/7%)

Query:  28 VRPRELRVMLRSVPAPAPG--EVRLQMRCVGICGSDVHYW----WHGSCGPFRLHDPMII  81
           ++P E  + L  V  P  G  ++ ++++   ICG+DVH +    W     P     PM++
Sbjct:   9 LKPEE-GIWLTEVEKPEMGHNDLLIRIKKTAICGTDVHIYNWDEWSQKTIPV----PMVV  63

Query:  82 GHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGS 141
           GHE  G V  +G  V   ++GDRV+ E  + C  C+ CR GR +LC N          G+
Sbjct:  64 GHEYVGEVVGIGQEVRGFEIGDRVSGEGHITCGHCRNCRGGRTHLCRNTTGVGVNRT-GA 122

Query: 142 LARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLN 201
            + Y+  PA   +++P  +S +  ++ +P   AVH    +   +G  VL+ GAGPIG++ 
Sbjct: 123 FSEYLVIPAFNAFKIPAGISDDLASIFDPFGNAVH-TALSFDLVGEDVLITGAGPIGIMA 181

Query: 202 CMVAKAFGASIIVVTDIDDRRLAFAETHAGADAV-INTRDLDEHDAALVVQQALDGAQAD 260
             VAK  GA  +V+TD+++ RL  A+      AV +    L++  + L + +       D
Sbjct: 182 AAVAKHVGARHVVITDVNEYRLDLAKKMGVTRAVNVMNEKLEDVMSELGMTEGF-----D 236

Query: 261 IALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVF--RYSNT 318
           + L+ +G  S     +  +  GG+I L+G+  S M V       + + I G++      T
Sbjct: 237 VGLEMSGNPSAFNSMLTNMNHGGKISLLGIPPSDMTVDWNQVIFKGLVIKGIYGREMFET 296

Query: 319 YPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAV 364
           +    +L+ SG +++ P+ITH +   +    +A F+  R+  +G V
Sbjct: 297 WYKMASLIQSG-LDLTPIITHHY---KIDDFQAGFDMMRSGMSGKV 338

ref|ZP_00279164.1| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Burkholderia fungorum LB400]
(343 aa)

Score: 134 bits (336), Expect: 5.78923e-30
Length: 335, Idn/Pos/Gap = 95/163/16 (28%/48%/4%)

Query:  35 VMLRSVPAPAPG--EVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEAL  92
           + L  V  P  G  +V +++    ICG+D+H W         +  PM +GHE  G +  +
Sbjct:  13 LTLTDVKKPEVGHNDVMIRITRTAICGTDIHIWKWDDWAQKTIPVPMHVGHEYVGEIVEM  72

Query:  93 GAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAW 152
           G  V    +GDRV+ E  + C  C+ CR GR +LC N         +G+ A Y+  PA  
Sbjct:  73 GQEVRGFAIGDRVSGEGHITCGFCRNCRAGRRHLCRNTVGVGVNR-EGAFAEYLVIPAFN 131

Query: 153 CYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASI 212
            +++P  +S +  A+ +P   A H    +   +G  VL+ GAGPIG++   +AK  GA  
Sbjct: 132 AFKIPPEISDDLAAIFDPFGNATH-TALSFNLVGEDVLITGAGPIGIMAVAIAKHVGARN 190

Query: 213 IVVTDIDDRRLAFAETHAGADAVINTRD-LDEHDAALVVQQALDGAQADIALDCAGLEST 271
           +V+TD++D RL  A       AV  +R+ L +  A L + +       D+ L+ +G+ S 
Sbjct: 191 VVITDVNDYRLELARKMGATRAVNVSRESLRDVMADLHMAEGF-----DVGLEMSGVPSA 245

Query: 272 MRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVF--RYSNTYPTCIALLASG 329
               +  +  GG+I L+G+  +   +       + ++I G++      T+   +A+L SG
Sbjct: 246 FTGMLEAMNHGGKIALLGIPPAQTAIDWTQVIFKGLEIKGIYGREMFETWYKMVAMLQSG 305

Query: 330 RVNVKPLITHRFMGLEESSLEAAFETARTAANGAV 364
            +++ P++TH F   +      AF T  +  +G V
Sbjct: 306 -LDLSPILTHHF---KVDDYREAFATMLSGESGKV 336

ref|YP_202323.1| threonine 3-dehydrogenase [Xanthomonas oryzae pv. oryzae KACC10331]
gb|AAW76938.1| threonine 3-dehydrogenase [Xanthomonas oryzae pv. oryzae KACC10331]
(344 aa)

Score: 134 bits (336), Expect: 6.03586e-30
Length: 251, Idn/Pos/Gap = 84/123/7 (33%/49%/2%)

Query:  40 VPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSL  99
           VP P P EV +++    ICG+D+H +         +   + IGHE  G V  LG+ VT  
Sbjct:  24 VPTPGPNEVLIKLEKTAICGTDLHIYLWDEWSQRTIKPGLTIGHEFVGRVAELGSAVTGY  83

Query: 100 QVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPES 159
           QVG RV+ E  + C  C+ CR GR +LCPN        V+G+ A Y+  PA+  + +P+ 
Sbjct:  84 QVGQRVSAEGHIVCGHCRNCRGGRPHLCPNTMGIGV-NVNGAFAEYMVMPASNLWPIPDQ 142

Query: 160 VSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDID 219
           +  E  A  +P   A H        IG  VL+ GAGPIG++   + K  GA  +VVTD++
Sbjct: 143 IPSELAAFFDPYGNAAHCALEF-DVIGEDVLITGAGPIGIIAAGICKHIGARNVVVTDVN 201

Query: 220 DRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVV 279
           D RL  A    GA  V+N       D    V   L     D+ L+ +G        +  +
Sbjct: 202 DFRLKLA-ADMGATRVVNVSKTSLKD----VMADLHMEGFDVGLEMSGNPRAFNDMLDCM 256

Query: 280 RPGGRICLVGM 290
             GG+I ++G+
Sbjct: 257 YHGGKIAMLGI 267

gb|AAM35905.1| threonine 3-dehydrogenase [Xanthomonas axonopodis pv. citri str. 306]
ref|NP_641369.1| threonine 3-dehydrogenase [Xanthomonas axonopodis pv. citri str. 306]
sp|Q8PNN2|TDH_XANAC L-threonine 3-dehydrogenase
(340 aa)

Score: 133 bits (335), Expect: 6.56109e-30
Length: 251, Idn/Pos/Gap = 83/123/7 (33%/49%/2%)

Query:  40 VPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSL  99
           VP P P EV +++    ICG+D+H +         +   + IGHE  G V  LG+ VT  
Sbjct:  20 VPTPGPNEVLIKLEKTAICGTDLHIYLWDEWSQRTIEPGLTIGHEFVGRVAELGSAVTGY  79

Query: 100 QVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPES 159
           Q+G RV+ E  + C  C+ CR GR +LCPN        V+G+ A Y+  PA+  + +P+ 
Sbjct:  80 QIGQRVSAEGHIVCGHCRNCRGGRPHLCPNTVGIGV-NVNGAFAEYMVMPASNLWPIPDQ 138

Query: 160 VSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDID 219
           +  E  A  +P   A H        IG  VL+ GAGPIG++   + K  GA  +VVTD++
Sbjct: 139 IPSELAAFFDPYGNAAHCALEF-DVIGEDVLITGAGPIGIIAAGICKHIGARNVVVTDVN 197

Query: 220 DRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVV 279
           D RL  A    GA  V+N       D    V   L     D+ L+ +G        +  +
Sbjct: 198 DFRLKLA-ADMGATRVVNVSKTSLKD----VMADLHMEGFDVGLEMSGNSRAFNDMLDCM 252

Query: 280 RPGGRICLVGM 290
             GG+I ++G+
Sbjct: 253 YHGGKIAMLGI 263

ref|NP_466185.1| hypothetical protein lmo2663 [Listeria monocytogenes EGD-e]
emb|CAD00876.1| lmo2663 [Listeria monocytogenes]
pir||AF1407 polyol dehydrogenase homolog lmo2663 [imported] - Listeria monocytogenes (strain EGD-e)
(343 aa)

Score: 133 bits (335), Expect: 7.07276e-30
Length: 332, Idn/Pos/Gap = 111/167/28 (33%/50%/8%)

Query:  47 EVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGDRVA 106
           +V++++   GICGSD+H +      P     P+ +GHE +GVV  +G  VTS++VGDRV 
Sbjct:  28 KVKIKVAFTGICGSDIHTFKGEYKNP---TTPVTLGHEFSGVVVEVGPDVTSIKVGDRVT  84

Query: 107 LEPGV-PCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPESVSLEEG 165
            E     C +C  C+E  YNLC N +   T   +GS A +V      C+ L E +SLE  
Sbjct:  85 SETTFETCGECIYCKEHDYNLCSNRRGIGT-QANGSFAEFVLSREESCHVLDERISLEAA 143

Query: 166 AMCEPLSVAVHANRRAGTTI--GSLVLVLGAGPIGLLNCMVAKAFGASII---VVTDIDD 220
           A+ EPL+  VH+     TTI     VLV G GPIGLL   V KA GA++I   +  D D 
Sbjct: 144 ALTEPLACCVHSALEK-TTIRPDDTVLVFGPGPIGLLLAQVVKAQGATVIMAGITKDSDR 202

Query: 221 RRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVVR 280
            RLA      G D +++T    + D A VV     G  A+   DC+G    +   + + +
Sbjct: 203 LRLA---KELGMDRIVDTL---KEDLAEVVLGMTGGYGAERVFDCSGAVPAVNQGLPLTK 256

Query: 281 PGGRICLVGMGSSAMHVPLVDASS---REIDIFGV-FRYSNTYPTCIALLASGRVNVKPL 336
             G    VG+ +   +   +D  S   REI   G   +  +++   + LLA+G+++   +
Sbjct: 257 KKGDFVQVGLFAEKKNA--IDEESIIQREIAYIGSRSQKPSSWILALDLLANGKIDTDKM 314

Query: 337 ITHRFMGLEESSLEAAFETARTAANGAVKVML 368
           IT +  GL++     AFE     A   +KV++
Sbjct: 315 IT-KVYGLDD--WREAFEA--VMAGNEIKVLV 341

ref|YP_082343.1| zinc-containing alcohol dehydrogenase; possible sorbitol dehydrogenase (L-iditol 2-dehydrogenase) [Bacillus cereus ZK]
gb|AAU19504.1| zinc-containing alcohol dehydrogenase; possible sorbitol dehydrogenase (L-iditol 2-dehydrogenase) [Bacillus cereus ZK]
(340 aa)

Score: 133 bits (335), Expect: 7.56097e-30
Length: 313, Idn/Pos/Gap = 95/161/16 (30%/51%/5%)

Query:  31 RELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVE  90
           +++R+  R      P +V++++   GICGSD+H + H    P  ++   ++GHE +G + 
Sbjct:  10 KDIRIEERETKELQPNDVKVKVAWAGICGSDLHAYLHPDSVP--MNKNTVLGHEFSGEIV  67

Query:  91 ALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPA 150
            +G+ VT  + GDRV + P +           R+     +       +DG  A YV  P 
Sbjct:  68 EVGSHVTKFKEGDRVCIYP-MMLKDPSNAETERFITLDAVG----AQIDGGFAEYVILPQ 122

Query: 151 AWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGA 210
              +++P+++SLE  AM EP +V+  + + +    G  V+V GAGPIGL   + AKA GA
Sbjct: 123 KTIFKIPDNLSLEVAAMVEPAAVSFQSIKDSNVEEGDTVVVYGAGPIGLFAVLGAKAAGA 182

Query: 211 SIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLES 270
           S I+V D+ D RL  A T  GA    N ++++  +   + +   DG  AD+ ++ AG+ES
Sbjct: 183 SNIIVVDLFDSRLGKA-TEVGATHTFNAKEVNPVEE--IRKLFPDG--ADVTIEAAGVES 237

Query: 271 TMRLAMHVVRPGGRICLVGMGSSAM--HVPLVDASSREIDIFGVFRYSN-TYPTCIALLA 327
           T   A+   +  G + ++   +  +  + P     S  + + G   YSN TY   I LLA
Sbjct: 238 TFNQAIQSTKVRGTMMVISFHTQDIQFNAPASLLFS-GVKLMGSVGYSNETYNEVIQLLA 296

Query: 328 SGRVNVKPLITHR 340
           +GR+  + +IT +
Sbjct: 297 NGRLPAQSIITSK 309

ref|NP_668172.1| putative dehydrogenase [Yersinia pestis KIM]
gb|AAS60608.1| putative Zinc-binding dehydrogenase [Yersinia pestis biovar Medievalis str. 91001]
ref|NP_991731.1| putative Zinc-binding dehydrogenase [Yersinia pestis biovar Medievalis str. 91001]
gb|AAM84423.1| putative dehydrogenase [Yersinia pestis KIM]
(382 aa)

Score: 133 bits (335), Expect: 7.62433e-30
Length: 320, Idn/Pos/Gap = 95/154/15 (29%/48%/4%)

Query:  30 PRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVH------YWWHGSCGPFRLHDPMIIGH  83
           PR+ R     VP     E+ +++   GIC  D         +W     P  +  PMI GH
Sbjct:  38 PRDYRFERVPVPTIDAKEILVKVEGCGICAGDTKAFEGAPSFWGDDKQPAYIKAPMIPGH  97

Query:  84 ESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFA-TPPVDGSL 142
           E  G V  LGA V   ++GDRV  E  VPC  C+ C  G+Y +C     +     V+G++
Sbjct:  98 EFIGHVVGLGADVEGFELGDRVTSEQIVPCWGCRFCNHGQYWMCEKHDLYGFQSNVNGAM 157

Query: 143 ARYV-CHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLN 201
           A Y+     A  Y +P+ + LE+  + EP + A HA +RA   +G +V++ G+G +GL  
Sbjct: 158 AEYLKFTKEAINYHVPDHLPLEKAILIEPYACAFHAVQRAKIKLGDVVVLAGSGTLGLGM 217

Query: 202 CMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVIN-TRDLDEHDAALVVQQALDGAQAD 260
               K  GA+ ++V D+ D RLA A+   GAD V+N +RD    D   ++++   G   D
Sbjct: 218 IGAIKKSGAAKLIVLDLSDDRLALAKKF-GADLVLNPSRD----DVNTLIKEMTGGYGCD 272

Query: 261 IALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSR-EIDIFGVFRYSNTY 319
           I +D  G +  +   + ++R  G      +    + V     S R E+D+ G       +
Sbjct: 273 IYIDATGAQKAVEQGLTLLRKLGTFVEFSVFKDPVTVDWSIISDRKELDVLGSHLGPYCF 332

Query: 320 PTCIALLASGRVNVKPLITH 339
           P  I  +++G +  + ++TH
Sbjct: 333 PLVIEGISNGDLPTEGVVTH 352

ref|YP_069321.1| putative Zinc-binding dehydrogenase [Yersinia pseudotuberculosis IP 32953]
emb|CAH20020.1| putative Zinc-binding dehydrogenase [Yersinia pseudotuberculosis IP 32953]
emb|CAC92582.1| putative Zinc-binding dehydrogenase [Yersinia pestis CO92]
ref|NP_406815.1| putative Zinc-binding dehydrogenase [Yersinia pestis CO92]
pir||AB0407 probable Zinc-binding dehydrogenase YPO3352 [imported] - Yersinia pestis (strain CO92)
(371 aa)

Score: 133 bits (335), Expect: 7.62433e-30
Length: 320, Idn/Pos/Gap = 95/154/15 (29%/48%/4%)

Query:  30 PRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVH------YWWHGSCGPFRLHDPMIIGH  83
           PR+ R     VP     E+ +++   GIC  D         +W     P  +  PMI GH
Sbjct:  27 PRDYRFERVPVPTIDAKEILVKVEGCGICAGDTKAFEGAPSFWGDDKQPAYIKAPMIPGH  86

Query:  84 ESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFA-TPPVDGSL 142
           E  G V  LGA V   ++GDRV  E  VPC  C+ C  G+Y +C     +     V+G++
Sbjct:  87 EFIGHVVGLGADVEGFELGDRVTSEQIVPCWGCRFCNHGQYWMCEKHDLYGFQSNVNGAM 146

Query: 143 ARYV-CHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLN 201
           A Y+     A  Y +P+ + LE+  + EP + A HA +RA   +G +V++ G+G +GL  
Sbjct: 147 AEYLKFTKEAINYHVPDHLPLEKAILIEPYACAFHAVQRAKIKLGDVVVLAGSGTLGLGM 206

Query: 202 CMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVIN-TRDLDEHDAALVVQQALDGAQAD 260
               K  GA+ ++V D+ D RLA A+   GAD V+N +RD    D   ++++   G   D
Sbjct: 207 IGAIKKSGAAKLIVLDLSDDRLALAKKF-GADLVLNPSRD----DVNTLIKEMTGGYGCD 261

Query: 261 IALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSR-EIDIFGVFRYSNTY 319
           I +D  G +  +   + ++R  G      +    + V     S R E+D+ G       +
Sbjct: 262 IYIDATGAQKAVEQGLTLLRKLGTFVEFSVFKDPVTVDWSIISDRKELDVLGSHLGPYCF 321

Query: 320 PTCIALLASGRVNVKPLITH 339
           P  I  +++G +  + ++TH
Sbjct: 322 PLVIEGISNGDLPTEGVVTH 341

ref|YP_007809.1| probable threonine 3-dehydrogenase [Parachlamydia sp. UWE25]
emb|CAF23534.1| probable threonine 3-dehydrogenase [Parachlamydia sp. UWE25]
(342 aa)

Score: 133 bits (334), Expect: 8.56905e-30
Length: 334, Idn/Pos/Gap = 100/162/17 (29%/48%/5%)

Query:  37 LRSVPAPA---PGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALG  93
           + ++P P+     EV ++     ICG+DVH +   +     +  P++IGHE  G +   G
Sbjct:  15 MENLPIPSHVKDDEVLIKTIKTSICGTDVHIYKWDAWAQKNVPVPLVIGHEFIGEIAEFG  74

Query:  94 AGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWC 153
             V   ++G+RV  E  + C QC  CR GR ++C + K      + G  A Y   PA   
Sbjct:  75 KNVKGFKIGERVCGEGHIVCNQCPNCRMGRKHVCMHTKGLGY-HISGCFAEYFVLPAENV 133

Query: 154 YRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASII 213
           + LP S+S + GA+ +P   AVH    A   IG  VL+ GAGPIG++   +AK  GA  I
Sbjct: 134 FSLPPSISDDLGAIFDPYGNAVHTT-LAFNLIGEDVLITGAGPIGIMAAAIAKQAGARHI 192

Query: 214 VVTDIDDRRLAFAETHAGADAV-INTRDLDEHDAALVVQQALDGAQADIALDCAGLESTM 272
           V+TD++D RL  A T   + A+ +N   LD    +L ++         + L+ +G    +
Sbjct: 193 VITDVNDYRLDLARTMGVSHAINVNRESLDNFMQSLGIKYGF-----TVGLEMSGHPDGL 247

Query: 273 RLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVF--RYSNTYPTCIALLASGR 330
           +     +R GG I L+G+   A  +       + + + G++     +T+   + LL  G 
Sbjct: 248 KTLTEKIRHGGNIALLGILPPATSIDWNLVIFKMLTLKGIYGREIFSTWYQMVHLLEIG- 306

Query: 331 VNVKPLITHRFMGLEESSLEAAFETARTAANGAV 364
           +N+ P+ITH F      + E  FE   +  +G V
Sbjct: 307 LNLAPIITHHF---SVDNFEKGFEVMLSGQSGKV 337

gb|EAA77877.1| hypothetical protein FG07683.1 [Gibberella zeae PH-1]
ref|XP_387859.1| hypothetical protein FG07683.1 [Gibberella zeae PH-1]
(363 aa)

Score: 133 bits (334), Expect: 8.56905e-30
Length: 348, Idn/Pos/Gap = 97/165/18 (27%/47%/5%)

Query:  35 VMLRSVPAPA--PGEVRLQMRCVGICGSDVHYWWHGSC---GPFRLH------DPMIIGH  83
           + L SVP     P  VR+  +  GICG+DVH +  G+     P   H       P+ +GH
Sbjct:  18 IRLESVPVKPLDPTTVRIAPKFCGICGTDVHEYLGGNNLIPKPGTPHGITGETSPLTLGH  77

Query:  84 ESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLA 143
           E +G+VE +G+ VT LQ GDRV ++P +   +C+ C+ G  N C    F       G LA
Sbjct:  78 EFSGIVEEVGSEVTRLQKGDRVCVQPIIYDNECRSCKRGLQNCCDQNGFIGLSGWGGGLA 137

Query: 144 RYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCM 203
                P     +LP++VSLE GA+ EPL+V  HA + +    G+   V+G GPIGL    
Sbjct: 138 ESTVVPQDAVKKLPDNVSLEVGALVEPLAVGWHATKISPYEDGNSAFVVGGGPIGLAVVQ 197

Query: 204 VAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIAL 263
                G   I++T++  +R  FA+          T+D    D   +V++   G  AD+  
Sbjct: 198 ALVGRGCKNIMLTEVSSKRREFAKKFGAHHVFDPTKD----DVVAMVKKLTGGLGADVGF 253

Query: 264 DCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYS-NTYPTC 322
           D AG +  + +A   ++    +  + +      + +     RE    G   Y+   +   
Sbjct: 254 DAAGSQHAIDVAFDCLKARAVLVNIAVWEKRAQLNMNQIVFRERSYVGCATYALGDFEEV 313

Query: 323 IALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLTI 370
           I  L++G++  + +IT + + +++  +E  F+T     +  VK+++ +
Sbjct: 314 IDALSNGKIKPEGMIT-KVIKMDK-VVEEGFQTLINDKDNHVKILVDV 359

dbj|BAD03964.1| alcohol dehydrogenase [Gordonia sp. TY-5]
(351 aa)

Score: 133 bits (334), Expect: 9.16055e-30
Length: 345, Idn/Pos/Gap = 103/166/26 (29%/48%/7%)

Query:  40 VPAPA---PGEVRLQMRCVGICGSDVHYWWHG--SCGPFRLHDPMIIGHESAGVVEALGA  94
           VP P    P +V ++M    ICG+D+H       +  P R     I+GHE  G +  +G 
Sbjct:  17 VPDPKLSEPTDVIVKMDTTTICGTDLHILKGDVPAVTPGR-----ILGHEGVGTITEVGD  71

Query:  95 GVTSLQVGDRVALEPGVPCLQCQRCREGRYNLC------PNIKFFATPPVDGSLARYVCH 148
            VT+L VGD+V L     C +C  C++G Y+ C        I +     +DG+ A YV  
Sbjct:  72 AVTTLAVGDQVILSCISSCGKCSFCKQGVYSHCLGSEGTSGIGWIFGHLIDGTQAEYVRV 131

Query: 149 PAA--WCYRLPESVSLEEGAMCEPLSVAVH--ANRRAGTTIGSLVLVLGAGPIGLLNCMV 204
           P A    ++LP +VS E+G +   +    H    R      G +V V+G GP+GL     
Sbjct: 132 PYAENSVHKLPSAVSPEQGTLLSDILPTGHEIGVRHGAVKPGDVVAVIGTGPVGLAAIAT 191

Query: 205 AKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALD 264
           A  +G S ++  DID  R+  A      D V++T      +    +    DG   D+A++
Sbjct: 192 AGLYGPSRVIAVDIDANRVEQARRFGATDGVVSTSSGWREE----ILAMTDGLGVDVAIE 247

Query: 265 CAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIA 324
             G+  T ++ + +VRP G +  VG+    + +P+ D     I +      +NT  T + 
Sbjct: 248 AVGIPDTFQMCLDIVRPAGHVANVGVHGKPVELPIQDLWISNIVMSMGLVNTNTLGTLLK 307

Query: 325 LLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLT 369
           L+A  R++ +P I+HRF GL E  ++A    +R A   A+KV+++
Sbjct: 308 LVAQRRIDPEPFISHRF-GLGE-IIDAYDVFSRAAETKALKVIMS 350

ref|YP_108389.1| putative zinc-binding dehydrogenase [Burkholderia pseudomallei K96243]
emb|CAH35789.1| putative zinc-binding dehydrogenase [Burkholderia pseudomallei K96243]
(363 aa)

Score: 133 bits (334), Expect: 1.0645e-29
Length: 355, Idn/Pos/Gap = 111/173/30 (31%/48%/8%)

Query:  30 PRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVH-------YWWHGSCGPFRLHDPMIIG  82
           P + RV   + P     E+ +++   GIC SD         +W  G   P+ +  P+I G
Sbjct:  19 PEDYRVERVAKPRANARELVIRIGACGICASDCKCHAGAKMFW--GGPSPW-VKAPVIPG  75

Query:  83 HESAGVVEALGAGVTS---LQVGDRVALEPGVPCLQCQRCREGRYNLCP--NIKFFATPP 137
           HE  G VEALG G      + +GDRV  E  VPC  C+ C+ G+Y +C   +I  F    
Sbjct:  76 HEFFGYVEALGEGAAEHFGVALGDRVIAEQIVPCGTCRYCKSGQYWMCEVHHIFGFQREV 135

Query: 138 VDGSLARYVCHPA-AWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGP 196
            DG +A Y+  P+ A  + +P  +SLE+ A+ EPL+ A+H   R    +  +V++ GAGP
Sbjct: 136 ADGGMAEYMRIPSGAIVHPVPLGISLEDAAIIEPLACAIHTVNRGDIQLDDVVVIAGAGP 195

Query: 197 IGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDG 256
           +GL+   VAK      +VV D  + R A A  + GAD  I   D    DA  +V+    G
Sbjct: 196 LGLMMTQVAKLKTPRRLVVVDPVEARRALARAY-GADVTI---DPAREDAPAIVRALTGG 251

Query: 257 AQADIALDCAGLESTMRLAMHVVRPGGRICLVGM--GSSAMHVPLVDASSREIDIFGVFR 314
              D+ ++  G+ + +   M ++R  GR     +    +A+   ++    +E+D+ G   
Sbjct: 252 YGCDVYIETTGVPAGVTQGMALIRKLGRFVEFSVFGKDTALDWSII-GDRKELDVRGAHL 310

Query: 315 YSNTYPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAAN-GAVKVML 368
               YP  I LLA G V  K ++TH F      SL+   E  R A +  ++KV++
Sbjct: 311 GPYCYPVAIDLLARGLVTSKGIVTHGF------SLDEWDEAIRVANSLDSIKVLM 359

emb|CAD74171.1| probable zinc-type alcohol dehydrogenase [Rhodopirellula baltica SH 1]
ref|NP_866632.1| probable zinc-type alcohol dehydrogenase [Rhodopirellula baltica SH 1]
(396 aa)

Score: 132 bits (333), Expect: 1.16683e-29
Length: 316, Idn/Pos/Gap = 107/156/21 (33%/49%/6%)

Query:  30 PRELRVMLRSVPAPAPG--EVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAG  87
           P    V +R +  P  G  +V L++  VG+CGSD+H W      P  ++ P+++GHE  G
Sbjct:  65 PEPGSVEIREIDRPEIGSQDVLLEVSHVGVCGSDLHQWTAHHSWP--VNYPVVLGHEFGG 122

Query:  88 VVEALGAGVTSLQVGDRVALE-PGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYV 146
            +  LG+ V   + GDRV  E   +        R G YNL P  K F    V+G++ RYV
Sbjct: 123 HIVQLGSDVEGWKEGDRVVSETAAIIDSNNPMSRRGLYNLDPTRKGFGYG-VNGAMTRYV 181

Query: 147 CHPAAWCYRLPESVSLEEGAMCEPLSVAVHAN-RRAGTTIGSLVLVLGAGPIGLLNCMVA 205
             P+   + +P S++ E   + EP  VA +A  R A    G  V+V+G G IG+L   +A
Sbjct: 182 RVPSRILHEVPHSLAFEHACLTEPCCVAYNAVVRNARIEPGDRVIVMGPGTIGILCAAMA 241

Query: 206 KAFGASIIVVTDIDDR-RLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALD 264
           +  GA + +V    DR RL  AE + G   ++     D  D A       DG   D  +D
Sbjct: 242 RLCGAEVALVGLESDRHRLNIAEENYGCQGIVG----DPTDWA----NQRDGLGCDGVID 293

Query: 265 CAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPT--- 321
            AG   T+ +AM VVRP G I  VG G   +   L     + + + G F  S+ +P    
Sbjct: 294 AAGSSVTLEIAMQVVRPAGWISKVGWGPQPLGYNLDPLVQKNVTLQGSF--SHNWPIWER 351

Query: 322 CIALLASGRVNVKPLI 337
            +ALL SG++NV P+I
Sbjct: 352 VLALLTSGQLNVAPII 367

ref|NP_636331.1| threonine 3-dehydrogenase [Xanthomonas campestris pv. campestris str. ATCC 33913]
gb|AAM40255.1| threonine 3-dehydrogenase [Xanthomonas campestris pv. campestris str. ATCC 33913]
pir||JC5524 L-threonine 3-dehydrogenase (EC 1.1.1.103) - Xanthomonas campestris pv. campestris
gb|AAC45449.1| threonine dehydrogenase [Xanthomonas campestris pv. campestris]
sp|O34268|TDH_XANCP L-threonine 3-dehydrogenase
(340 aa)

Score: 132 bits (333), Expect: 1.28971e-29
Length: 251, Idn/Pos/Gap = 84/123/7 (33%/49%/2%)

Query:  40 VPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSL  99
           VP P P EV +++    ICG+D+H +         +   + IGHE  G V  LG+ VT  
Sbjct:  20 VPTPGPNEVLIKLEKTAICGTDLHIYLWDEWSQRTITPGLTIGHEFVGRVAELGSAVTGY  79

Query: 100 QVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPES 159
           QVG RV+ E  + C  C+ CR GR +LCPN        V+G+ A Y+  PA+  + +P+ 
Sbjct:  80 QVGQRVSAEGHIVCGHCRNCRGGRPHLCPNTVGIGV-NVNGAFAEYMVMPASNLWPIPDQ 138

Query: 160 VSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDID 219
           +  E  A  +P   A H        IG  VL+ GAGPIG++   + K  GA  +VVTD++
Sbjct: 139 IPSELAAFFDPYGNAAHCALEF-DVIGEDVLITGAGPIGIIAAGICKHIGARNVVVTDVN 197

Query: 220 DRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVV 279
           D RL  A    GA  V+N       D    V   L     D+ L+ +G        +  +
Sbjct: 198 DFRLKLA-ADLGATRVVNVSKTSLKD----VMADLHMEGFDVGLEMSGNPRAFNDMLDCM 252

Query: 280 RPGGRICLVGM 290
             GG+I ++G+
Sbjct: 253 YHGGKIAMLGI 263

ref|YP_129939.1| putative threonine 3-dehydrogenase [Photobacterium profundum SS9]
emb|CAG20137.1| putative threonine 3-dehydrogenase [Photobacterium profundum SS9]
(327 aa)

Score: 132 bits (333), Expect: 1.34465e-29
Length: 331, Idn/Pos/Gap = 92/162/22 (27%/48%/6%)

Query:  41 PAPAPGEVRLQMRCVGICGSDVHYW----WHGSCGPFRLHDPMIIGHESAGVVEALGAGV  96
           P     ++ ++++   ICG+DVH +    W     P     PM++GHE  G V  +G  V
Sbjct:   7 PEMGHNDLLIRIKKTAICGTDVHIYNWDEWSQKTIPV----PMVVGHEYVGEVVGIGQEV  62

Query:  97 TSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRL 156
               +GDRV+ E  + C  C+ CR GR +LC N         DG+ A ++  PA   +++
Sbjct:  63 RGFTIGDRVSGEGHITCGHCRNCRGGRTHLCRNTTGVGVNR-DGAFAEFLVIPAFNAFKI 121

Query: 157 PESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVT 216
           P  +S +  ++ +P   AVH    +   +G  VL+ GAGPIG++   VAK  GA  +V+T
Sbjct: 122 PAGISDDLASIFDPFGNAVH-TALSFDLVGEDVLITGAGPIGIMAAAVAKHVGARHVVIT 180

Query: 217 DIDDRRLAFAETHAGADAV-INTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLA 275
           D+++ RL  A       AV +    L++  + L + +       D+ L+ +G+ S     
Sbjct: 181 DVNEYRLDLARKMGVTRAVNVANEKLEDVMSELGMTEGF-----DVGLEMSGVPSAFNGM 235

Query: 276 MHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVF--RYSNTYPTCIALLASGRVNV 333
           +  +  GG++ L+G+  S M V       + + I G++      T+    +L+ SG +++
Sbjct: 236 LASMNHGGKVALLGIPPSDMAVDWTQVIFKGLVIKGIYGREMFETWYKMASLIQSG-LDL 294

Query: 334 KPLITHRFMGLEESSLEAAFETARTAANGAV 364
            P+ITH +   +    +  F+  R+  +G V
Sbjct: 295 TPIITHHY---KIDDFQKGFDMMRSGMSGKV 322

emb|CAD65626.1| L-iditol 2-dehydrogenase [Lactobacillus plantarum WCFS1]
ref|NP_786748.1| L-iditol 2-dehydrogenase [Lactobacillus plantarum WCFS1]
(352 aa)

Score: 132 bits (332), Expect: 1.48625e-29
Length: 316, Idn/Pos/Gap = 107/160/23 (33%/50%/7%)

Query:  37 LRSVPAP--APGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGA  94
           L+ +P P     +V L++   GICG+D+H +            P+++GHE +G V  +G 
Sbjct:  16 LKQIPIPEVTGDKVLLKVAYTGICGTDIHTFKGQYANAV---TPLVLGHEFSGEVVEVGP  72

Query:  95 GVTSLQVGDRVALEPGVPCL-QCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWC 153
            V +L+ GDRV  E        C  C++  YNLCPN     T   +GS+A YV       
Sbjct:  73 DVKTLKPGDRVTSETTFATDGTCVYCQDKEYNLCPNRVGIGTK-ANGSMANYVLTREESA 131

Query: 154 YRLPESVSLEEGAMCEPLSVAVHA-NRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASI 212
           + LP++VS +  AM EPL+  VHA  ++   T+   +L++G GP+GLL+  +AK  GA +
Sbjct: 132 HILPDNVSYKMAAMSEPLASCVHAMYQKTPFTLHDTLLIMGPGPMGLLSLQIAKEIGAFV 191

Query: 213 IV--VTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLES 270
           IV  +T  D  RL  A+   GAD +++T+   + D A VV  A DG       DC+G   
Sbjct: 192 IVSGITK-DADRLQIAK-ELGADIIVDTQ---KEDLAKVVMDATDGVGVTKVYDCSGATP 246

Query: 271 TMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASS---REIDIFGVFRYSNTYPTCIALL- 326
            +  A+ ++R GG    VG+ +  M+   +D  S    EI   G  R  N Y   IAL  
Sbjct: 247 AVNSALPLIRKGGTFQQVGLFAKPMNE--LDERSIIQHEITYRGS-RSQNPYDWAIALHL 303

Query: 327 -ASGRVNVKPLITHRF 341
            + G +N   +IT  F
Sbjct: 304 ESKGAINQDAMITKVF 319

ref|YP_102876.1| oxidoreductase, zinc-binding dehydrogenase family [Burkholderia mallei ATCC 23344]
gb|AAU47447.1| oxidoreductase, zinc-binding dehydrogenase family [Burkholderia mallei ATCC 23344]
(353 aa)

Score: 132 bits (332), Expect: 1.71275e-29
Length: 355, Idn/Pos/Gap = 111/173/30 (31%/48%/8%)

Query:  30 PRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVH-------YWWHGSCGPFRLHDPMIIG  82
           P + RV   + P     E+ +++   GIC SD         +W  G   P+ +  P+I G
Sbjct:   9 PEDYRVERVAKPRANARELVIRIGACGICASDCKCHAGAKMFW--GGPSPW-VKAPVIPG  65

Query:  83 HESAGVVEALGAGVTS---LQVGDRVALEPGVPCLQCQRCREGRYNLCP--NIKFFATPP 137
           HE  G VEALG G      + +GDRV  E  VPC  C+ C+ G+Y +C   +I  F    
Sbjct:  66 HEFFGYVEALGEGAAEHFGVALGDRVIAEQIVPCGTCRYCKSGQYWMCEVHHIFGFQREV 125

Query: 138 VDGSLARYVCHPA-AWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGP 196
            DG +A Y+  P+ A  + +P  +SLE+ A+ EPL+ A+H   R    +  +V++ GAGP
Sbjct: 126 ADGGMAEYMRIPSGAIVHPIPLGISLEDAAIIEPLACAIHTVNRGDIQLDDVVVIAGAGP 185

Query: 197 IGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDG 256
           +GL+   VAK      +VV D  + R A A  + GAD  I   D    DA  +V+    G
Sbjct: 186 LGLMMTQVAKLKTPRRLVVVDPVEARRALARAY-GADVTI---DPAREDAPAIVRALTGG 241

Query: 257 AQADIALDCAGLESTMRLAMHVVRPGGRICLVGM--GSSAMHVPLVDASSREIDIFGVFR 314
              D+ ++  G+ + +   M ++R  GR     +    +A+   ++    +E+D+ G   
Sbjct: 242 YGCDVYIETTGVPAGVTQGMALIRKLGRFVEFSVFGKDTALDWSII-GDRKELDVRGAHL 300

Query: 315 YSNTYPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAAN-GAVKVML 368
               YP  I LLA G V  K ++TH F      SL+   E  R A +  ++KV++
Sbjct: 301 GPYCYPVAIDLLARGLVTSKGIVTHGF------SLDEWDEAIRVANSLDSIKVLM 349

emb|CAH16274.1| hypothetical protein [Legionella pneumophila str. Lens]
ref|YP_127370.1| hypothetical protein lpl2034 [Legionella pneumophila str. Lens]
(346 aa)

Score: 131 bits (330), Expect: 2.92152e-29
Length: 340, Idn/Pos/Gap = 102/166/22 (30%/48%/6%)

Query:  41 PAPA---PGEVRLQMRCVGICGSDVHYWWHG--SCGPFRLHDPMIIGHESAGVVEALGAG  95
           P P    P +  +++    ICG+D+H       +C P R     I+GHE  GVV+ +G G
Sbjct:  18 PTPIITNPTDAIIKVTKTTICGTDLHILKGDVVTCVPGR-----ILGHEGIGVVDKVGQG  72

Query:  96 VTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAA--WC 153
           VT  Q GD V +     C +C+ CR+G Y+ C    +     +DG+ A YV  P A    
Sbjct:  73 VTEFQKGDLVLISCITSCSKCEYCRKGMYSHCAKGGWILGNTIDGTQAEYVRIPYADTSL 132

Query: 154 YRLPESVSLEEGAM-CEPLSVAVHANRRAG-TTIGSLVLVLGAGPIGLLNCMVAKAFGAS 211
           Y++PE +  +   M  + L        + G    G+ V ++GAGPIGL   + A+ +  +
Sbjct: 133 YKIPEGIDEDVLVMLSDILPTGFECGVQNGKVQPGNTVAIVGAGPIGLSTLLTAQFYSPA 192

Query: 212 IIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLEST 271
            I+V D+DD RL  A+   GA A +N+ D    D    + Q  +G   D A++  G+ +T
Sbjct: 193 EIIVIDLDDNRLEVAKRF-GATATVNSSDGKAVDK---IMQMTNGRGVDTAIEAVGIPAT 248

Query: 272 MRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASGRV 331
             +   +V PGG I  +G+      + L    S+ I I      + T P  +  +++ ++
Sbjct: 249 FVMCEDIVAPGGTIANIGVHGVKADLHLERLWSQNISITTRLVDTVTTPMLLKTVSAKKI 308

Query: 332 NVKPLITHRFMGLEESSLEAAFET-ARTAANGAVKVMLTI 370
           N   LI+HRF   + + +  A+ET A  A   A+KV++ +
Sbjct: 309 NPMLLISHRF---KFAKILDAYETFAHAADTHALKVIINV 345

gb|AAV96586.1| L-threonine 3-dehydrogenase [Silicibacter pomeroyi DSS-3]
ref|YP_168555.1| L-threonine 3-dehydrogenase [Silicibacter pomeroyi DSS-3]
(347 aa)

Score: 131 bits (330), Expect: 2.97068e-29
Length: 339, Idn/Pos/Gap = 109/173/12 (32%/51%/3%)

Query:  29 RPRELRVMLRS-VPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAG  87
           +P E   M+++ VP   P +V ++++  GICG+D+H W         +  PMI GHE AG
Sbjct:  13 KPEEGLWMVQAPVPEIGPDDVLIKIKKTGICGTDIHIWNWDEWAAHTVPVPMITGHEFAG  72

Query:  88 VVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVC 147
            +  LG  VT L +G RV+ E  +   + ++ R G+++L P  +      V G+ A+Y+ 
Sbjct:  73 EIVELGRDVTGLSIGQRVSGEGHLIGTESRQSRAGKFHLDPGTRGIGVN-VQGAFAQYLR 131

Query: 148 HPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKA 207
            PA     LPE +  E GA+ +PL  AVH    +   +G  VL+ GAGPIG++   VAK 
Sbjct: 132 LPAFNVVPLPEDIPDEIGAILDPLGNAVHT-ALSFDLLGEDVLITGAGPIGIMAAAVAKH 190

Query: 208 FGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAG 267
            GA  +V+TDI+  RL  A+ H    A   T D+   D   VV +       D+ L+ +G
Sbjct: 191 AGARHVVITDINADRLKLAQ-HVVPRA--RTVDVTREDLGDVVHELGLKQGFDVGLEMSG 247

Query: 268 LESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVF--RYSNTYPTCIAL 325
            ++ +   +  +  GG+I L+G+      V       + I I GV+      T+   IA+
Sbjct: 248 SQAALDQMVEALVMGGKIALLGIPPGKSPVDWSRIVFKAITIKGVYGREMFETWYKMIAM 307

Query: 326 LASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAV 364
           L +G ++V  +ITHRF G++E      F   ++  +G V
Sbjct: 308 LQNG-LDVSRVITHRF-GVDE--FREGFAAMKSGLSGKV 342

ref|YP_094738.1| threonine(-3-)dehydrogenase [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
gb|AAU26791.1| threonine(-3-)dehydrogenase [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
(342 aa)

Score: 131 bits (329), Expect: 3.48101e-29
Length: 339, Idn/Pos/Gap = 96/164/16 (28%/48%/4%)

Query:  31 RELRVMLRSVPAPAPG--EVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGV  88
           +E  + ++ +P P  G  +V ++++   ICG+D+H +         +  PM +GHE  G 
Sbjct:  11 KEPGIWMQDIPVPEYGVNDVLIKIKRTAICGTDIHIYSWDEWAQATIPVPMTVGHEFYGE  70

Query:  89 VEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPN-IKFFATPPVDGSLARYVC 147
           +  +G  V  L+VG RV+ E  + C  C+ CR G+ +LC N +      P  G  A Y+ 
Sbjct:  71 IVEVGKEVQGLKVGQRVSGEGHITCGFCRNCRAGKRHLCRNTLGVGVNRP--GCFAEYLA 128

Query: 148 HPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKA 207
            PA     LP++++ E+ A+ +P   A H    A   +G  VL+ GAGPIG++   + + 
Sbjct: 129 LPATNVIALPDNITEEQAAILDPFGNAAHC-ALAFDVVGEDVLITGAGPIGIMAAAIVRH 187

Query: 208 FGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAG 267
            GA  +V+TD++D RL  A    G    +N +     D A  +   L+G   D+ L+ +G
Sbjct: 188 IGARHVVITDVNDHRLELAR-QMGVSRAVNVKYQKLSDVANELGM-LEG--FDVGLEMSG 243

Query: 268 LESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVF--RYSNTYPTCIAL 325
               +   M  +  GG + L+G+      +       + + I G++      T+   IA+
Sbjct: 244 NPMALNDMMKAMNHGGHVALLGIPPQETPIDWNQVIFKGLVIKGIYGREMFETWYKMIAM 303

Query: 326 LASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAV 364
           L SG +N+ P+ITH F        + AF+   +  +G V
Sbjct: 304 LQSG-LNISPVITHNF---PVDEYQHAFQIMASGQSGKV 338

emb|CAH14973.1| threonine dehydrogenase [Legionella pneumophila str. Lens]
ref|YP_126101.1| threonine dehydrogenase [Legionella pneumophila str. Lens]
(340 aa)

Score: 130 bits (328), Expect: 4.66157e-29
Length: 339, Idn/Pos/Gap = 96/164/16 (28%/48%/4%)

Query:  31 RELRVMLRSVPAPAPG--EVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGV  88
           +E  + ++ +P P  G  +V ++++   ICG+D+H +         +  PM +GHE  G 
Sbjct:   9 KEPGIWMQDIPVPEYGVNDVLIKIKRTAICGTDIHIYSWDEWAQATIPVPMTVGHEFYGE  68

Query:  89 VEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPN-IKFFATPPVDGSLARYVC 147
           +  +G  V  L+VG RV+ E  + C  C+ CR G+ +LC N +      P  G  A Y+ 
Sbjct:  69 IVEVGKEVQGLKVGQRVSGEGHITCGFCRNCRAGKRHLCRNTLGVGVNRP--GCFAEYLA 126

Query: 148 HPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKA 207
            PA     LP++++ E+ A+ +P   A H    A   +G  VL+ GAGPIG++   + + 
Sbjct: 127 LPATNVIALPDNITEEQAAILDPFGNAAHC-ALAFDVVGEDVLITGAGPIGIMAAAIVRH 185

Query: 208 FGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAG 267
            GA  +V+TD++D RL  A    G    +N +     D A  +   L+G   D+ L+ +G
Sbjct: 186 IGARHVVITDVNDHRLELARK-MGVSRAVNVKYQKLSDVANELGM-LEG--FDVGLEMSG 241

Query: 268 LESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVF--RYSNTYPTCIAL 325
               +   M  +  GG + L+G+      +       + + I G++      T+   IA+
Sbjct: 242 NPMALNDMMKAMNHGGHVALLGIPPQETPIDWNQVIFKGLVIKGIYGREMFETWYKMIAM 301

Query: 326 LASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAV 364
           L SG +N+ P+ITH F        + AF+   +  +G V
Sbjct: 302 LQSG-LNISPVITHNF---PVDEYQHAFQIMASGQSGKV 336

ref|NP_435459.1| putative zinc-binding [Sinorhizobium meliloti 1021]
gb|AAK64871.1| putative zinc-binding [Sinorhizobium meliloti 1021]
pir||E95288 probable zinc-binding [imported] - Sinorhizobium meliloti  (strain 1021) magaplasmid pSymA
(337 aa)

Score: 130 bits (327), Expect: 5.50814e-29
Length: 299, Idn/Pos/Gap = 98/145/15 (32%/48%/5%)

Query:  31 RELRVM-LRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVV  89
           R+LRV  +  + AP PG V L++R  GICGSD+H +  G     R   P   GHE  G V
Sbjct:  10 RDLRVEEVAELAAPPPGFVNLEVRAAGICGSDLHNYRTGQWISRR---PSTAGHEFCGRV  66

Query:  90 EALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHP 149
            A+G GV+ L  GD V+ +  + C  C  C  GR N+C  + F      DG  A  V  P
Sbjct:  67 TAIGEGVSHLVRGDVVSADSRMWCGTCPACASGRSNVCETLGFLGEV-CDGGFAEAVQLP 125

Query: 150 AAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFG 209
           +   +R    +S    AM EPL+VA+HA RR     G+ VLV+G G IG L+ ++     
Sbjct: 126 SRLVFRHDPKLSPHVAAMAEPLAVALHAVRRLAVPDGAPVLVMGCGTIGGLSALLLSRLH 185

Query: 210 ASIIVVTDID-DRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGL 268
              +++TD++ D+    AE   G    ++            +++AL G +   ALD  G 
Sbjct: 186 QGPLLLTDLNADKAALVAEVTGGVVVALD---------GAAIEEALPGTRLRHALDATGS 236

Query: 269 ESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLA 327
              +  A+ ++  GG + LVG+G   + +       REI + G   ++   P  I LLA
Sbjct: 237 IQAIARALDILSGGGALALVGIGHGKLDLDPNILVEREISLVGCHAFAGELPEAIELLA 295

dbj|BAC74065.1| putative zinc-binding dehydrogenase [Streptomyces avermitilis MA-4680]
ref|NP_827530.1| putative zinc-binding dehydrogenase [Streptomyces avermitilis MA-4680]
(329 aa)

Score: 130 bits (327), Expect: 6.45438e-29
Length: 302, Idn/Pos/Gap = 93/142/19 (30%/47%/6%)

Query:  41 PAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQ 100
           P P P EV +++   G+CG+D+H       G F    P++ GHE AG V  LG  VT + 
Sbjct:  20 PTPGPREVVVEVAACGLCGTDLHILQ----GEFAPKLPIVPGHEFAGEVVGLGTQVTEVS  75

Query: 101 VGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPESV 160
           VGDRVA++P + C +C+ CR G  NLC            G+ ARY   P A C +LPE V
Sbjct:  76 VGDRVAVDPSLYCYECRYCRTGHNNLCERWAAIGVTTAGGA-ARYAVAPVANCVKLPEHV 134

Query: 161 SLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDD 220
             ++ A+ EPLS AV       + +G+ VLV G+G +GL+   +AK  GA+ + V D++ 
Sbjct: 135 RTQDAALIEPLSCAVRGYDVLRSRLGAHVLVYGSGTMGLMMLELAKRTGAASVDVVDVNP 194

Query: 221 RRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVVR 280
            RL  A     + +  N  +LD                 D+ +D  G  + ++  +  V 
Sbjct: 195 ARLTTARQLGVSGSAANADELDRPQG------------WDVVVDATGNAAAIQDGLGRVA 242

Query: 281 PGGRICLVGMGSSAMHVPL--VDASSREIDIFGVFRYSNTYPTCIALLASGRVNVKPLIT 338
             G     G+   A  V +      ++EI I G     +++     L A G ++    I+
Sbjct: 243 KAGTFLQFGVADYATRVTIDPYRIYNQEITITGSMAVLHSFERAAELFAGGVLDPDVFIS 302

Query: 339 HR 340
            R
Sbjct: 303 DR 304

emb|CAH11905.1| threonine dehydrogenase [Legionella pneumophila str. Paris]
ref|YP_123095.1| threonine dehydrogenase [Legionella pneumophila str. Paris]
(340 aa)

Score: 130 bits (327), Expect: 6.61798e-29
Length: 339, Idn/Pos/Gap = 96/164/16 (28%/48%/4%)

Query:  31 RELRVMLRSVPAPAPG--EVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGV  88
           +E  + ++ +P P  G  +V ++++   ICG+D+H +         +  PM +GHE  G 
Sbjct:   9 KEPGIWMQDIPVPEYGVNDVLIKIKRTAICGTDIHIYSWDEWAQATIPVPMTVGHEFYGE  68

Query:  89 VEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPN-IKFFATPPVDGSLARYVC 147
           +  +G  V  L+VG RV+ E  + C  C+ CR G+ +LC N +      P  G  A Y+ 
Sbjct:  69 IVEVGKEVQGLKVGQRVSGEGHITCGFCRNCRAGKRHLCRNTLGVGVNRP--GCFAEYLA 126

Query: 148 HPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKA 207
            PA     LP++++ E+ A+ +P   A H    A   +G  VL+ GAGPIG++   + + 
Sbjct: 127 LPATNVIALPDNITEEQAAILDPFGNAAHC-ALAFDVVGEDVLITGAGPIGIMAAAIVRH 185

Query: 208 FGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAG 267
            GA  +V+TD++D RL  A    G    +N +     D A  +   L+G   D+ L+ +G
Sbjct: 186 IGARHVVITDVNDHRLELAR-QMGVSRAVNVKYQKLIDVANELGM-LEG--FDVGLEMSG 241

Query: 268 LESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVF--RYSNTYPTCIAL 325
               +   M  +  GG + L+G+      +       + + I G++      T+   IA+
Sbjct: 242 NPMALNDMMKAMNHGGHVALLGIPPQETPIDWNQVIFKGLVIKGIYGREMFETWYKMIAM 301

Query: 326 LASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAV 364
           L SG +N+ P+ITH F        + AF+   +  +G V
Sbjct: 302 LQSG-LNISPVITHNF---PVDEYQHAFQIMASGQSGKV 336

ref|YP_071048.1| putative sorbitol dehydrogenase [Yersinia pseudotuberculosis IP 32953]
emb|CAH21776.1| putative sorbitol dehydrogenase [Yersinia pseudotuberculosis IP 32953]
(408 aa)

Score: 129 bits (325), Expect: 1.19675e-28
Length: 350, Idn/Pos/Gap = 100/164/23 (28%/46%/6%)

Query:  30 PRELRVMLRSVPAPAPGEVRLQMRCVGICGSD------VHYWWHGSCGPFRLHDPMIIGH  83
           P++ R+     P P   E+ ++++  GIC  D         +W  +  P+ +  P++ GH
Sbjct:  69 PQDYRLEHVPTPVPKAKELVIKVKGCGICAGDCKCKNGAKMFWGET--PW-VKPPVVPGH 125

Query:  84 ESAGVVEALGAGVTS-LQVGDRVALEPGVPCLQCQRCREGRYNLCP--NIKFFATPPVDG 140
           E  G + ALG G  S  ++G+RV  E  VPC  C+ C  G Y +C   NI  F     +G
Sbjct: 126 EFYGHIVALGEGTESKYKIGERVIAEQIVPCWDCRYCNSGSYWMCETHNIYGFQKDVAEG 185

Query: 141 SLARYV-CHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGL 199
            +A Y+     A  +++PES+S E+  + EP++ A+H   R    +  +V++ GAGP+GL
Sbjct: 186 GMAEYMRFSENAIVHKIPESLSHEDAVLIEPMACAIHTVARGDIQLDDVVVLAGAGPLGL 245

Query: 200 LNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQA 259
               VA+      ++V D  + RLA A+   GAD VIN     + DA  +V+    G   
Sbjct: 246 CMVQVARLKTPKKLIVIDTIEERLALAKAF-GADVVINPL---KEDADKIVKSLTGGYGC 301

Query: 260 DIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPL-VDASSREIDIFGVFRYSNT 318
           D+ ++  G    +   + ++R  GR     +      V   +    +E+DI G      +
Sbjct: 302 DVYIEATGAPIGVTQGLQMIRKLGRFVEFSVFGQETTVDWSIIGDRKELDIRGAHLAPYS 361

Query: 319 YPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVML 368
           Y     L   G V  K ++TH +        E AFE A +    ++KV+L
Sbjct: 362 YEIATDLFERGLVTSKGIVTHSY---SLDDWEKAFELADS--TNSIKVIL 406

dbj|BAA75343.1| sorbitol dehydrogenase [Bacillus halodurans]
(306 aa)

Score: 129 bits (324), Expect: 1.21689e-28
Length: 260, Idn/Pos/Gap = 89/128/16 (34%/49%/6%)

Query:  37 LRSVPAPAPG-----EVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEA  91
           LR    PAP      ++ ++++ VGICGSD+  +     GP+     M  GHE AG V  
Sbjct:  12 LRFEETPAPSIEHDDDIIIKVKAVGICGSDLSRY--KKLGPYV--PGMTFGHEFAGEVVK  67

Query:  92 LGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFF-ATPPVDGSLARYVCHPA 150
           +G  VT   +GDRVA  P   C QC+ C+ G    C  +    A  P  G+ A YV  PA
Sbjct:  68 IGRSVTGFSIGDRVAACPTYTCGQCRYCQLGEPTRCERLSVIGARHP--GAYAEYVKLPA 125

Query: 151 AWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGA 210
                LP  V+ +E A+ EP SV  H   R     G+ V ++G G IGLL    AK FGA
Sbjct: 126 KHVIPLPNVVNYDEAALIEPASVVAHGFYRTNIKPGASVAIMGVGSIGLLAVQWAKIFGA 185

Query: 211 SIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLES 270
           + +   DID+++L  A    GAD +I++     H   L   +  +G   D+A++ AG  S
Sbjct: 186 TTVFAIDIDEQKLNVA-NQLGADVLISSLQRPAHKQIL---EYTNGIGVDVAVESAGTPS 241

Query: 271 TMRLAMHVVRPGGRICLVGM 290
           T      + + GG +  +G+
Sbjct: 242 TSAQVFALPKKGGEVVFLGI 261

ref|ZP_00303607.1| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Novosphingobium aromaticivorans DSM 12444]
(335 aa)

Score: 128 bits (322), Expect: 2.16413e-28
Length: 303, Idn/Pos/Gap = 101/142/17 (33%/46%/5%)

Query:  39 SVPAPAPGE--VRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGV  96
           ++P P PGE  V +++   GICGSD+H     + G        ++GHE AG V ALG GV
Sbjct:  17 TIPDPTPGEGDVVVKVGRCGICGSDLHMTEDPAYGQ---GAGSVLGHEFAGEVVALGKGV  73

Query:  97 TSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRL 156
             L+ GD V++ P   C QC  CR G    C            G  A +       C RL
Sbjct:  74 EGLRTGDLVSVIPLQSCGQCHSCRTGEVQWCERFGLQG-----GGYAEFALTRPNQCVRL 128

Query: 157 PESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVT 216
           P S S+ +GA+ EPL+VA+H    +   IG  VLVLGAGPIGL     A+ FGA  +VV 
Sbjct: 129 PASASMADGAIVEPLAVALHGLALSRMKIGDKVLVLGAGPIGLAVAFWARRFGAGRVVVQ 188

Query: 217 DIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAM 276
           D+ + +   A      D V+     D  D      +AL G +ADI  +C G+   +  A+
Sbjct: 189 DLAEWQRDRALQMGAHDFVV-----DAADPVGSAGRAL-GGKADIVFECVGVPGLIAQAV 242

Query: 277 HVVRPGGRICLVGMGSSAMHVPLVDASSREIDIF-GVFRYSNTYPTCIALLASGRVNVKP 335
             VR  G I L+G+ +           S+++ +    F     Y   +  L  G V  + 
Sbjct: 243 EQVRNDGTITLLGLCTRPDTFNSFAMLSKQVKLVTSAFFTRQEYEAALDALVRGAVEPRL 302

Query: 336 LIT 338
           L+T
Sbjct: 303 LVT 305

gb|AAS55855.1| mannitol dehydrogenase [Lactobacillus reuteri]
(336 aa)

Score: 128 bits (322), Expect: 2.45266e-28
Length: 318, Idn/Pos/Gap = 95/147/16 (29%/46%/5%)

Query:  26 VLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHES  85
           VL   ++L +     P   P EV +     GICG+D    + G  G      P+++GHE+
Sbjct:   5 VLTGKKQLEIEDIKEPEIKPDEVLIHTAYAGICGTD-KALYAGLPGSASAVPPIVLGHEN  63

Query:  86 AGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARY 145
           +GVV  +G+ VT+++ GDRV ++P + C QC+ CR  R  LC ++        +G    Y
Sbjct:  64 SGVVTKVGSEVTNVKPGDRVTVDPNIYCGQCKYCRTQRPELCEHLDAVGVTR-NGGFEEY 122

Query: 146 VCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVA 205
              PA   Y +P+ VSL+  A+ EP+S A+H      T      LVLG G  G L   + 
Sbjct: 123 FTAPAKVVYPIPDDVSLKAAAVVEPISCAMHGVDLLETHPYQKALVLGDGFEGQLFAQIL 182

Query: 206 KAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDC 265
           KA G   + +    D +L     H G   +  T++    DA             DI ++ 
Sbjct: 183 KARGIHEVTLAGRSDEKLENNRKHFGVKTIDTTKEEIPADA------------YDIVVEA 230

Query: 266 AGLESTMRLAMHVVRPGGRICLVGMGS--SAMHVPLVDASSREIDIFGVFRYSNTYPTCI 323
            GL +T   A+     G ++ + G+G+      V   D   +++ I G F    T+   I
Sbjct: 231 VGLPATQEQALAAAARGAQVLMFGVGNPDDKFSVNTYDVFQKQLTIQGAFVNPYTFEDSI 290

Query: 324 ALLASGRVNVKPLITHRF 341
           ALL+SG V+  PL +H  
Sbjct: 291 ALLSSGVVDPLPLFSHEL 308

gb|AAL60173.1| GatD [Klebsiella oxytoca]
(346 aa)

Score: 128 bits (322), Expect: 2.62196e-28
Length: 354, Idn/Pos/Gap = 109/172/53 (30%/48%/14%)

Query:  33 LRVMLRSVPA-PAPGEVRLQMRCVGICGSDV--------HYWWHGSCGPFRLHDPMIIGH  83
           +RV  R +P      +V +++   G+CGSD+        HY+            P+ +GH
Sbjct:  12 VRVEERPIPTLQTENDVLVKVVSSGLCGSDIPRTFAKGAHYY------------PITLGH  59

Query:  84 ESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLA 143
           E +G VE+ G+ VT LQ GD VA  P +PCL C    +G Y+     +F  +   DG+  
Sbjct:  60 EFSGYVESYGSAVTDLQPGDGVACVPLLPCLICPDWLKGFYSQWAKYEFVGSRG-DGAFT 118

Query: 144 RYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCM 203
            Y+       +   + + +++GA+ EP++V +HA   A     + V+++GAG +GLL   
Sbjct: 119 EYIVVNRKNVFVCADRMPIDDGALIEPMTVGLHAFHLAQAAKEN-VIIIGAGTMGLLALQ 177

Query: 204 VAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQAD-IA 262
            A+  GA  I   DI+ +RLA A+T  GA  V N++++   +    +Q AL+  Q D + 
Sbjct: 178 CARELGAKSITAIDINPQRLALAKT-LGATYVFNSKEMSSKE----IQTALEEIQFDQLV 232

Query: 263 LDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASS-------REIDIFGVF-R 314
           L+ AG   T+ L + V  P  ++ LVG     +H  L   S+       +E+ I G +  
Sbjct: 233 LETAGTPQTVALGIEVAGPRAQLALVG----TLHHDLTLLSATFGQILRKELTIVGSWMN 288

Query: 315 YSNTYP-----TCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGA 363
           YS  +P     T + LL   R+ + PLI H  +G  ES     F     A NGA
Sbjct: 289 YSGPWPGEEWQTAVRLLTEKRIQLVPLIAH--IGNAES-----FAREVQALNGA 335

ref|YP_106361.1| oxidoreductase, zinc-binding dehydrogenase family [Burkholderia mallei ATCC 23344]
gb|AAU45824.1| oxidoreductase, zinc-binding dehydrogenase family [Burkholderia mallei ATCC 23344]
(378 aa)

Score: 128 bits (321), Expect: 2.874e-28
Length: 323, Idn/Pos/Gap = 97/151/15 (30%/46%/4%)

Query:  30 PRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYW------WHGSCGPFRLHDPMIIGH  83
           P++ R+    VP P P E+  Q+  VGIC  D+  +      W  +  P  +  PMI GH
Sbjct:  33 PQDYRLEQVPVPKPGPDEILTQVERVGICMGDIKTFRGAPSFWGDAVQPRYVKPPMIPGH  92

Query:  84 ESAGVVEALGAGVT--SLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFA-TPPVDG 140
           E    V ALG G     ++VGDRV  E  VPC  C+ C  G+Y +C     +     V G
Sbjct:  93 EFVCRVVALGPGAERRGVKVGDRVISEQIVPCWSCRFCGHGQYWMCQKHDLYGFQNNVHG 152

Query: 141 SLARY-VCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGL 199
           ++A Y +    A  +R+P+S+  +E  + EPLS ++HA  RA      +V+V GAG +GL
Sbjct: 153 AMAEYMIFTKEAIVHRVPDSIPTDEAILIEPLSCSLHAADRANVGFDDVVVVAGAGTLGL 212

Query: 200 LNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQA 259
                A+      ++V D+   R A A    GAD V N     E +    ++    G   
Sbjct: 213 GIIGAARLRHPKQLIVLDMKPERAALAR-RMGADDVWNPA---EENVIEKIRAITGGYGC 268

Query: 260 DIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPL-VDASSREIDIFGVFRYSNT 318
           DI ++  G    +   + ++R  GR     + +    V   +    +E+D+ G       
Sbjct: 269 DIYIEATGHHRAVGQGLAMLRKLGRFVEFSVFNDEASVDWSIIGDRKELDVLGSHLGPYM 328

Query: 319 YPTCIALLASGRVNVKPLITHRF 341
           YP  I  +AS R++V+ ++TH F
Sbjct: 329 YPRAIEFIASRRIDVRGIVTHTF 351

gb|AAS62523.1| putative zinc-binding dehydrogenase [Yersinia pestis biovar Medievalis str. 91001]
ref|NP_993646.1| putative zinc-binding dehydrogenase [Yersinia pestis biovar Medievalis str. 91001]
(395 aa)

Score: 128 bits (321), Expect: 3.25718e-28
Length: 350, Idn/Pos/Gap = 100/164/23 (28%/46%/6%)

Query:  30 PRELRVMLRSVPAPAPGEVRLQMRCVGICGSD------VHYWWHGSCGPFRLHDPMIIGH  83
           P++ R+     P P   E+ ++++  GIC  D         +W  +  P+ +  P++ GH
Sbjct:  56 PQDYRLEHVPTPVPKAKELVIKVKGCGICAGDCKCKNGAKMFWGET--PW-VKPPVVPGH 112

Query:  84 ESAGVVEALGAGVTS-LQVGDRVALEPGVPCLQCQRCREGRYNLCP--NIKFFATPPVDG 140
           E  G + ALG G  S  ++G+RV  E  VPC  C+ C  G Y +C   NI  F     +G
Sbjct: 113 EFYGHIVALGEGTESKYKLGERVIAEQIVPCWDCRYCNSGSYWMCETHNIYGFQKDVAEG 172

Query: 141 SLARYV-CHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGL 199
            +A Y+     A  +++PES+S E+  + EP++ A+H   R    +  +V++ GAGP+GL
Sbjct: 173 GMAEYMRFSENAIVHKIPESLSHEDAVLIEPMACAIHTVARGDIQLDDVVVLAGAGPLGL 232

Query: 200 LNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQA 259
               VA+      ++V D  + RLA A+   GAD VIN     + DA  +V+    G   
Sbjct: 233 CMVQVARLKTPKKLIVIDTIEERLALAKAF-GADVVINPL---KEDADKIVKSLTGGYGC 288

Query: 260 DIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPL-VDASSREIDIFGVFRYSNT 318
           D+ ++  G    +   + ++R  GR     +      V   +    +E+DI G      +
Sbjct: 289 DVYIEATGAPIGVTQGLQMIRKLGRFVEFSVFGQETTVDWSIIGDRKELDIRGAHLAPYS 348

Query: 319 YPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVML 368
           Y     L   G V  K ++TH +        E AFE A +    ++KV+L
Sbjct: 349 YEIATDLFERGLVTSKGIVTHSY---SLDDWEKAFELADS--TNSIKVIL 393

gb|AAU22909.1| putative Zn binding dehydrogenase [Bacillus subtilis phage PBSX]
ref|YP_090955.1| hypothetical protein BLi01358 [Bacillus licheniformis ATCC 14580]
ref|YP_078547.1| putative Zn binding dehydrogenase [Bacillus licheniformis ATCC 14580]
gb|AAU40262.1| putative protein [Bacillus licheniformis DSM 13]
(337 aa)

Score: 127 bits (320), Expect: 4.21866e-28
Length: 287, Idn/Pos/Gap = 91/142/14 (31%/49%/4%)

Query:  26 VLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCG--PFRLHDPMIIGH  83
           V  +P   ++    +P    GE  ++++ +GICG+D H +    CG  PF  + P ++GH
Sbjct:   5 VCEKPYRFKMTDVKMPELKDGEALVRIKRIGICGTDFHAY----CGRQPFFSY-PRVLGH  59

Query:  84 ESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLA 143
           E +G + ++     +L+ GD+V++ P + C  C  CR GR N C N+        DG + 
Sbjct:  60 ELSGEIVSIDNSGGTLKPGDQVSIIPYLECGACIACRNGRPNCCVNLNVLGVH-TDGGMR 118

Query: 144 RYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCM 203
            Y+  PA    +  E ++L E A+ E LS+  HA  RA    G  VLV+GAGPIGL    
Sbjct: 119 EYINVPADHLLK-TEGLTLSEAAVVECLSIGAHAAERANIKKGETVLVVGAGPIGLSVMK 177

Query: 204 VAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIAL 263
            AK  GA +I + D+   RL F+   A AD V+    L    AA  +++  +G       
Sbjct: 178 FAKLKGAKVIAM-DVRKERLTFSRRWAEADEVV----LGGEHAADEIKRLTNGDFPTAVF 232

Query: 264 DCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIF 310
           D  G  ++M  A      GGR+  VG+ +  + +P  +   RE+ I 
Sbjct: 233 DATGHPASMNSAYQYAAHGGRLIYVGLVNDHLAMPDPEIHMRELTIL 279

emb|CAB46402.1| putative zinc-binding dehydrogenase [Streptomyces coelicolor A3(2)]
ref|NP_626167.1| putative zinc-binding dehydrogenase [Streptomyces coelicolor A3(2)]
pir||T36915 probable zinc-binding dehydrogenase - Streptomyces coelicolor
(329 aa)

Score: 127 bits (319), Expect: 4.62418e-28
Length: 312, Idn/Pos/Gap = 97/151/23 (31%/48%/7%)

Query:  34 RVMLRSVPAPAPG--EVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEA  91
           R ++  VP P PG  EV +++   G+CG+D+H       G F    P++ GHE AG V  
Sbjct:  11 RAVVTEVPDPTPGPREVVVEVAACGLCGTDLHILQ----GEFAPKLPIVPGHEFAGAVVG  66

Query:  92 LGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAA 151
           +GA VT + VGD+VA++P + C +C+ CR G  NLC            G+ A+Y   P A
Sbjct:  67 VGAQVTEVAVGDQVAVDPSLYCYECRYCRTGHNNLCERWAAIGVTTAGGA-AQYAVAPVA 125

Query: 152 WCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGAS 211
            C +LPE V  ++ A+ EPLS AV       + +G+ VL+ G+G +GL+   +AK  GA+
Sbjct: 126 NCVKLPEHVRTQDAALIEPLSCAVRGYDVLQSRLGAHVLIYGSGTMGLMMLELAKRTGAA 185

Query: 212 IIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQA-DIALDCAGLES 270
            + + D++  RL   ET  G     +    DE          LD  Q  D+ +D  G  +
Sbjct: 186 SVDMVDLNPARL---ETARGLGVSASAATPDE----------LDRPQGWDLVIDATGNAA 232

Query: 271 TMRLAMHVVRPGGRICLVGMGSSAMHVPL--VDASSREIDIFGVFRYSNTYPTCIALLAS 328
            ++  +  V   G     G+   A  V +      ++EI I G     ++Y     L A+
Sbjct: 233 AIQDGLDRVAKAGTFLQFGVADYATRVQIDPYRIYNQEITITGSMAVLHSYERAAELFAN 292

Query: 329 GRVNVKPLITHR 340
           G ++    I+ R
Sbjct: 293 GVLDPDVFISDR 304

ref|NP_669004.1| hypothetical protein y1686 [Yersinia pestis KIM]
emb|CAC91307.1| putative zinc-binding dehydrogenase [Yersinia pestis CO92]
gb|AAM85255.1| hypothetical [Yersinia pestis KIM]
ref|NP_406036.1| putative zinc-binding dehydrogenase [Yersinia pestis CO92]
pir||AG0305 probable L-iditol 2-dehydrogenase (EC 1.1.1.14) [imported] - Yersinia pestis (strain CO92)
(408 aa)

Score: 127 bits (319), Expect: 5.11115e-28
Length: 350, Idn/Pos/Gap = 100/164/23 (28%/46%/6%)

Query:  30 PRELRVMLRSVPAPAPGEVRLQMRCVGICGSD------VHYWWHGSCGPFRLHDPMIIGH  83
           P++ R+     P P   E+ ++++  GIC  D         +W  +  P+ +  P++ GH
Sbjct:  69 PQDYRLEHVPTPVPKAKELVIKVKGCGICAGDCKCKNGAKMFWGET--PW-VKPPVVPGH 125

Query:  84 ESAGVVEALGAGVTS-LQVGDRVALEPGVPCLQCQRCREGRYNLCP--NIKFFATPPVDG 140
           E  G + ALG G  S  ++G+RV  E  VPC  C+ C  G Y +C   NI  F     +G
Sbjct: 126 EFYGHIVALGEGTESKYKLGERVIAEQIVPCWDCRYCNSGSYWMCETHNIYGFQKDVAEG 185

Query: 141 SLARYV-CHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGL 199
            +A Y+     A  +++PES+S E+  + EP++ A+H   R    +  +V++ GAGP+GL
Sbjct: 186 GMAEYMRFSENAIVHKIPESLSHEDAVLIEPMACAIHTVARGDIQLDDVVVLAGAGPLGL 245

Query: 200 LNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQA 259
               VA+      ++V D  + RLA A+   GAD VIN     + DA  +V+    G   
Sbjct: 246 CMVPVARLKTPKKLIVIDTIEERLALAKAF-GADVVINPL---KEDADKIVKSLTGGYGC 301

Query: 260 DIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPL-VDASSREIDIFGVFRYSNT 318
           D+ ++  G    +   + ++R  GR     +      V   +    +E+DI G      +
Sbjct: 302 DVYIEATGAPIGVTQGLQMIRKLGRFVEFSVFGQETTVDWSIIGDRKELDIRGAHLAPYS 361

Query: 319 YPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVML 368
           Y     L   G V  K ++TH +        E AFE A +    ++KV+L
Sbjct: 362 YEIATDLFERGLVTSKGIVTHSY---SLDDWEKAFELADS--TNSIKVIL 406

ref|XP_393651.1| similar to hypothetical protein MG01114.4 [Apis mellifera]
(338 aa)

Score: 126 bits (317), Expect: 1.01311e-27
Length: 307, Idn/Pos/Gap = 89/151/26 (28%/49%/8%)

Query:  28 VRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAG  87
           V+   L +    VP P P +VR+++   GICG+D+H    GS  P +    + +GHE AG
Sbjct:   8 VKNHTLALRRADVPNPGPNDVRIRVAYSGICGTDLHIL-EGSF-PCKKDGFLTLGHEFAG  65

Query:  88 VVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPV--DGSLARY 145
            V+A+G+ V + +VG RVA++P   C  C  C +G Y  C      +T  +  DG  + +
Sbjct:  66 TVDAIGSSVKNFKVGQRVAVDPNSGCNTCNYCHDGSYQHCSAGGINSTIGIYKDGGFSTH 125

Query: 146 VCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGT-TIGSLVLVLGAGPIGLL-NCM 203
              P +  Y +P+ V L +  + EPLS   H  ++  +  +GS VLV+GAG IGLL  CM
Sbjct: 126 AIVPESQVYLIPDDVELHQAVLVEPLSCLAHGWKKLNSVNVGSNVLVIGAGIIGLLWACM 185

Query: 204 V-AKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLD-EHDAALVVQQALDGAQADI 261
           +       S+ +    + RR            ++   DLD E  +   ++ +      D+
Sbjct: 186 LHLHGLRKSVTISEPQEKRR-----------KLVTKLDLDFEAKSPEQLKNSY-----DV 229

Query: 262 ALDCAGLESTMRLAMHVVRPGGRICLVGMGS--SAMHVPLVDASSREIDIFGVFRYSNTY 319
            +DC+G    +  ++ ++ PGGR+C+ G+ +  +   +       +E+ I GV     ++
Sbjct: 230 VVDCSGSAPAIEASIPLLAPGGRLCIFGVANPKAKFSIEPFQVYLKELTILGVNINPFSF 289

Query: 320 PTCIALL 326
           P  + LL
Sbjct: 290 PRGLGLL 296

ref|XP_589947.1| PREDICTED: similar to Sorbitol dehydrogenase (L-iditol 2-dehydrogenase), partial [Bos taurus]
(107 aa)

Score: 126 bits (316), Expect: 1.25855e-27
Length: 107, Idn/Pos/Gap = 59/73/0 (55%/68%/0%)

Query:  48 VRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGDRVAL 107
           V L+M  VGICGSDVHYW HG  G F +  PM++GHE++G V  +G+ V  LQ GDRVA+
Sbjct:   1 VLLKMHSVGICGSDVHYWQHGRIGDFVVKKPMVLGHEASGTVVKVGSLVRHLQPGDRVAI  60

Query: 108 EPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCY 154
           EPG P    + C+ GRYNL P I F ATPP DG+L R+  H A +CY
Sbjct:  61 EPGAPRETDEFCKIGRYNLSPTIFFCATPPDDGNLCRFYKHNANFCY 107

gb|EAL21954.1| hypothetical protein CNBC0940 [Cryptococcus neoformans var. neoformans B-3501A]
gb|AAW42578.1| zinc-binding dehydrogenase, putative [Cryptococcus neoformans var. neoformans JEC21]
ref|XP_569885.1| zinc-binding dehydrogenase, putative [Cryptococcus neoformans var. neoformans JEC21]
(349 aa)

Score: 125 bits (315), Expect: 1.47476e-27
Length: 319, Idn/Pos/Gap = 93/147/18 (29%/46%/5%)

Query:  30 PRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVV  89
           PR  ++    VP   P E+ L++   G+CG+D H       G F    P++ GHE+ G +
Sbjct:  14 PRNFKITKVPVPEIGPEEILLKVDICGVCGTDQHI----HEGEFIAKFPLVPGHEAVGRI  69

Query:  90 EALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPV--DGSLARYVC 147
            ++G  V    +GDR+A + G  C  C  CR+G    C N   FA   V  DG  A Y+ 
Sbjct:  70 VSMGDKVKGFDIGDRIAADVGETCGYCHYCRKGTDLFCEN---FAPAGVARDGGFADYIK 126

Query: 148 HPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKA 207
           +  A CY++ ++++ EE  + EP S A+H         G+ VL++GAGP GL+   + K 
Sbjct: 127 YHFAKCYKI-KNLTDEEATLLEPASCAIHGMDVLKMPFGARVLLIGAGPTGLILAQLMKM 185

Query: 208 FGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQA--DIALDC 265
            GAS I +      ++  A     AD  I   DLD  +      +  +      D+  + 
Sbjct: 186 GGASHITIAANTGIKMEIARKVEAADEYI---DLDRSNPGPQWAKLKEDNPYGFDVVAEA 242

Query: 266 AGLESTMRLAMHVVRPGGRICLVGMGSSAMHV---PLVDASSREIDIFGVFRYSNTYPTC 322
            G+ES +  A++ V  GG + + G+      +      D    E  I G F  +  +P  
Sbjct: 243 TGVESLVNDAINYVTRGGTLLVYGVYEDKARLSGWSPTDIFVNEKRIIGSFSQTYCFPRA 302

Query: 323 IALLASGRVNVKPLITHRF 341
           I LL SG++    ++T  F
Sbjct: 303 IDLLDSGKIKTTGMVTDVF 321

emb|CAE22477.1| putative dehydrogenase [Streptomyces tenebrarius]
(339 aa)

Score: 125 bits (315), Expect: 1.51214e-27
Length: 321, Idn/Pos/Gap = 113/149/27 (35%/46%/8%)

Query:  30 PRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYW---WHGSCGPFRLHDPMIIGHESA  86
           P E     R VP PAPGE  + +    ICGSD+  +   WHG         P++ GHE +
Sbjct:   9 PGEAVFGTREVPVPAPGEALIHLGYNSICGSDLSLYRGVWHG------FSYPVVPGHEWS  62

Query:  87 G-VVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARY 145
           G VVE  G G     VG  V  +    C  C  C  G   LC N++       DG+ A Y
Sbjct:  63 GTVVEVNGPGAE--LVGRDVVGDLTCACGSCAACGRGTPVLCENLQELGFTR-DGACAEY 119

Query: 146 VCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVA 205
           +  P    + LPE +SL      EP++VA+HA    G   G  V VLGAG IGL+   VA
Sbjct: 120 MTIPTGNLHVLPEGLSLRAACQVEPVAVALHAVSTVGVEPGERVAVLGAGGIGLMLMQVA 179

Query: 206 KAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDC 265
           +  G  I  V +    R A A    GA  V   R     + A +V +  D    D+ L+ 
Sbjct: 180 RQRGGVITTVGEPVAERRAVA-AQLGARTVTTGR---PGELAELVAKHPD-LTPDVVLEA 234

Query: 266 AGLESTMRLAMHVVRPGGRICLVG-----MGSSAMHVPLVDASSREIDIFGVFRYSNTYP 320
           +G    ++ A+ VVRPGGRI LVG     +G  A H   V A    + I G       +P
Sbjct: 235 SGYPVAVQEAIEVVRPGGRIGLVGYRVEEVGPMATHHVAVKA----LTIRGSLGPGGRFP 290

Query: 321 TCIALLASGRVNVKPLITHRF 341
             I LLA G + V+PL++H F
Sbjct: 291 EAIDLLARGEIEVEPLLSHEF 311

dbj|BAC69339.1| putative threonine 3-dehydrogenase [Streptomyces avermitilis MA-4680]
ref|NP_822804.1| putative threonine 3-dehydrogenase [Streptomyces avermitilis MA-4680]
(342 aa)

Score: 125 bits (315), Expect: 1.58977e-27
Length: 334, Idn/Pos/Gap = 108/165/18 (32%/49%/5%)

Query:  37 LRSVPAP--APGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGA  94
           L  VP P   PG+V +++   GICG+D+H           +  P+++GHE  G V   G 
Sbjct:  15 LMDVPEPEIGPGDVLIKVLRTGICGTDLHIRSWDGWAQQAVRTPLVLGHEFVGEVVETGR  74

Query:  95 GVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAA--W 152
            V  ++ GDRV+ E  + C +C+ C+ GR +LC           DG+ A YV  PAA  W
Sbjct:  75 DVVDIKAGDRVSGEGHLVCGKCRNCQAGRRHLCRATVGLGVGR-DGAFAEYVALPAANVW 133

Query: 153 CYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASI 212
            +R+P  V L+  A+ +P   AVH    +   +G  VL+ GAGPIGL+   VA+  GA  
Sbjct: 134 VHRVP--VDLDVAAIFDPFGNAVH-TALSFPLVGEDVLITGAGPIGLMAAAVARHAGARN 190

Query: 213 IVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQA-DIALDCAGLEST 271
           +++TD+ + RL  A    G    +N  D    D     Q+AL   +  DI L+ +G    
Sbjct: 191 VMITDVSEERLELARK-IGVSLALNVADTTIADG----QRALGLREGFDIGLEMSGRPEA 245

Query: 272 MRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVF-RYSNTYPTCIALLASGR 330
           MR  +  +  GGRI ++G+ S    V      +  I I G++ R        +++L  G 
Sbjct: 246 MRDMIANMTHGGRIAMLGLPSQEFPVDWARIVTSMITIKGIYGREMFETWYAMSVLLEGG 305

Query: 331 VNVKPLITHRFMGLEESSLEAAFETARTAANGAV 364
           +++ P+IT R+ G  +   EAAF  A +   G V
Sbjct: 306 LDLAPVITGRY-GYRD--YEAAFADAASGRGGKV 336

ref|YP_218010.1| putative zinc-binding dehydrogenase [Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67]
gb|AAX66929.1| putative zinc-binding dehydrogenase [Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67]
(338 aa)

Score: 125 bits (315), Expect: 1.67138e-27
Length: 261, Idn/Pos/Gap = 86/132/9 (32%/50%/3%)

Query:  30 PRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVV  89
           P  +  + R +P     EV L+++ VGICG+D+H +      PF  + P ++GHE  GV 
Sbjct:   9 PGNIEYIERDIPHLKDDEVLLKIKAVGICGTDIHAF--AGRQPFFAY-PRVLGHEICGVA  65

Query:  90 EALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHP 149
           E LG   ++ +VG R ++ P +PC  C  CREG+ N C N+  +     DG  + Y+   
Sbjct:  66 EMLGKSCSTAKVGQRYSVIPCIPCGACAACREGKTNCCENVSLYGVHQ-DGGFSEYLAVR 124

Query: 150 AAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFG 209
                 L ++++   GA+ E  +++ HA RRA       +LV+GAGPIGL    +AKA G
Sbjct: 125 EQNLVELSDNLTDSAGALVECFAISAHAVRRADVKPQQNILVVGAGPIGLAAAAIAKAKG 184

Query: 210 ASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLE 269
           A  + V DID  R        G    + T D    D    ++    G  A   LD  G +
Sbjct: 185 AR-VAVADIDAERRRLVAEKVG----VATLDPSSDDYIDALKACFSGELAGTVLDATGNK 239

Query: 270 STMRLAMHVVRPGGRICLVGM 290
           S+M  A+ ++R GG+I  +G+
Sbjct: 240 SSMSRAVDLIRHGGKIVFIGL 260

emb|CAF34032.1| putative alcohol dehydrogenase [Micromonospora echinospora]
gb|AAR98562.1| GntP [Micromonospora echinospora]
(340 aa)

Score: 125 bits (315), Expect: 1.68539e-27
Length: 339, Idn/Pos/Gap = 108/164/34 (31%/48%/10%)

Query:  41 PAPAPGEVRLQMRCVGICGSDVHYW---WHGSCGPFRLHDPMIIGHESAGVVEALGAGVT  97
           P   PG   +++    +CGSD+  +   WHG+        P++ GHE AGVV++   G  
Sbjct:  24 PEAPPGWAVVKVHYCCLCGSDLWLYRGKWHGN------RYPIVPGHEWAGVVDSAPEGYE  77

Query:  98 SLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLP 157
           S  VG  V  +  V C  C  CR+G   +C N+       VDG  A YV  P    Y LP
Sbjct:  78 SW-VGRPVTGDLIVGCQGCGPCRDGLPVMCENLIEIGFT-VDGGCAGYVAVPITNLYLLP 135

Query: 158 ESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTD 217
           E + L   +  EPL+VA+HA  R        V VLGAG IG L    A+A GA++ + TD
Sbjct: 136 EGMDLAAASQTEPLAVALHAVDRINLRPAERVAVLGAGGIGQLILQSARATGATVTLATD 195

Query: 218 IDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMH 277
           +   R   AE  +GA A ++  +L E  +           + D+  + +G   ++  A+ 
Sbjct: 196 LVAERRKIAE-ESGAAAAVHPSELPELTSY--------ADKVDVVFEASGDPESVVRALD 246

Query: 278 VVRPGGRICLVGMGSSAMH------VPLVDASSREIDIFGVFRYSNTYPTCIALLASGRV 331
           +VRPGGR+CLVG    A H      +PL  AS     + GV      Y   + LLA+G +
Sbjct: 247 LVRPGGRVCLVGYQVGAEHALETARLPLSYAS-----LVGVMGPGGKYREAVDLLANGAI 301

Query: 332 NVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLTI 370
           + +P++T   + L++ +   A + A    +G V+V+  +
Sbjct: 302 DTQPILTD-IVTLDDYA--PAIDRAINRTDGTVRVVFDL 337

ref|NP_757283.1| Hypothetical zinc-type alcohol dehydrogenase-like protein yjjN [Escherichia coli CFT073]
gb|AAN83857.1| Hypothetical zinc-type alcohol dehydrogenase-like protein yjjN [Escherichia coli CFT073]
(340 aa)

Score: 125 bits (315), Expect: 1.72811e-27
Length: 310, Idn/Pos/Gap = 90/143/19 (29%/46%/6%)

Query:  37 LRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGV  96
           +R  P P   E  ++++ VGICG+D+H W      PF  + P ++GHE  G +   G  +
Sbjct:  19 VRERPVPGDNEALIKIKTVGICGTDIHAW--AGNQPFFSY-PRVLGHEICGEIIESGKNI  75

Query:  97 TSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRL 156
            +  +G +VA+ P + C QC  C+ GR N C  I        DG  + Y+  P A    L
Sbjct:  76 HNFNIGQQVAVIPYISCQQCPACKSGRTNCCEKISVIGVHQ-DGGFSEYLSVPVANI--L 132

Query: 157 P-ESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVV 215
           P + +  +  A+ EP +++ HA RRA       VLV+GAGPIGL    +AKA GA ++V 
Sbjct: 133 PADGIDPQAAALIEPFAISAHAVRRAAIAPSEQVLVVGAGPIGLGAAAIAKADGAQVVVA 192

Query: 216 TDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLA 275
                RR      H      +   D    D    ++    G+ A   +D  G +  M   
Sbjct: 193 DTSPARR-----EHVATRLELPVLDPSAEDFDAQLRAQFGGSLAQKVIDATGNQHAMNNT 247

Query: 276 MHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIA----LLASGRV 331
           ++++R GG +  VG+    +     +   +E  + G     N  P   A    L+A G++
Sbjct: 248 VNLIRHGGTVVFVGLFKGELQFSDPEFHKKETTMMGS---RNATPEDFAKVGRLMAEGKI 304

Query: 332 NVKPLITHRF 341
               ++THR+
Sbjct: 305 TADMMLTHRY 314

gb|EAA71750.1| hypothetical protein FG03061.1 [Gibberella zeae PH-1]
ref|XP_383237.1| hypothetical protein FG03061.1 [Gibberella zeae PH-1]
(387 aa)

Score: 125 bits (314), Expect: 2.0763e-27
Length: 349, Idn/Pos/Gap = 103/169/17 (29%/48%/4%)

Query:  35 VMLRSVPAPA--PGEVRLQMRCVGICGSDVHYWWHG-SCGPFRLHD------PMIIGHES  85
           + +  VP P+   G+V++    VGICG+D+H +  G +  P   H       P+ +GHE 
Sbjct:  44 IRVEQVPQPSVKAGQVKVAPAFVGICGTDLHEYLGGPNFCPTTPHPITKESIPVTLGHEF 103

Query:  86 AGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARY 145
           +G++  +G  V   +VG   A++P + C  C  C     N+C +  F       G L+  
Sbjct: 104 SGIITEVGPDVEGFEVGQPCAIQPTLFCGHCAACHNHAENVCHSGGFIGLSGSGGGLSES 163

Query: 146 VCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRA-GTTIGSLVLVLGAGPIGLLNCMV 204
           VC  A   + LP+ + LE GA+ EPLSV+ HA   A      S V++LG GPIGL   + 
Sbjct: 164 VCVNATHVHPLPQDLPLEIGALVEPLSVSWHAMTAAPDINPDSRVVILGGGPIGLAMILC 223

Query: 205 AKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALD 264
            KA G   I+V+++   R  FA    GA  V+N  + + ++  L + +   G  AD+  D
Sbjct: 224 LKAKGVDEIIVSEVATSRQKFAR-ELGATWVVNPIEENLNEIVLALTE---GKGADVVFD 279

Query: 265 CAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNT-YPTCI 323
           CAG+  +++ A  VVRP G +  + +    +       + +E     V  Y++  +   I
Sbjct: 280 CAGVPMSIKSACEVVRPKGTVVNLAIWEKEIPFNPNWITMKESSYKSVLGYTHKDFQAVI 339

Query: 324 ALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLTIPE 372
           A LASG +    +IT +     E+ +E   +      N  VKV++ + +
Sbjct: 340 ANLASGAIKPSQMITRKIK--LENIVEDGIKALIHDKNNQVKVLVDMSD 386

emb|CAD73603.1| zinc-type alcohol dehydrogenase [Rhodopirellula baltica SH 1]
ref|NP_865917.1| zinc-type alcohol dehydrogenase [Rhodopirellula baltica SH 1]
(342 aa)

Score: 125 bits (314), Expect: 2.11124e-27
Length: 303, Idn/Pos/Gap = 100/150/18 (33%/49%/5%)

Query:  43 PAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHD-PMIIGHESAGVVEALGAGVTSLQV 101
           P PGE  +++  VG+CG+D+     G  G F     P I GHE    V A+G GV +++V
Sbjct:  23 PGPGEALVRIHRVGVCGTDLG----GYLGKFPFFSYPRIPGHELGVEVVAVGEGVENVKV  78

Query: 102 GDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPESVS 161
           GDR ++EP + C +C  C  G  N C + +       DG L   +  PA   +    ++S
Sbjct:  79 GDRCSVEPYINCQKCYSCERGLTNCCESHQTLGV-MCDGGLTEKMILPARKLHP-ANNLS 136

Query: 162 LEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDR 221
            E+ A+ E L++  HA  RA  T    VLV+G+GPIGL     A+  GA +I V D+   
Sbjct: 137 YEQSALVETLAIGCHAIDRAHVTEKDTVLVIGSGPIGLSAIEFARVAGARVI-VADLSQT 195

Query: 222 RLAFAETHAGADAVINTRDLDEHDAALVVQQAL-DGAQADIALDCAGLESTMRLAMHVVR 280
           RL F     G   + +T   D  +A +   +A+ DG +AD+ +D  G   +MR AM +  
Sbjct: 196 RLDFVTEKMG---MTDTIQFDGSEADIEKLEAMTDGRRADVVVDATGNHHSMRRAMEMAA 252

Query: 281 PGGRICLVGMGSSAM---HVPLVDASSREIDIFGVFR-YSNTYPTCIALLASGRVNVKPL 336
            GGR+  VG+    +   H P +    RE+ I       +  +   I L+ SG ++  P 
Sbjct: 253 FGGRVVYVGITQQDLQFPHAPFL--HRRELTILASRNALTGDFARIIQLIESGVIDTDPW 310

Query: 337 ITH 339
           ITH
Sbjct: 311 ITH 313

ref|YP_110278.1| putative dehydrogenase [Burkholderia pseudomallei K96243]
emb|CAH37705.1| putative dehydrogenase [Burkholderia pseudomallei K96243]
(378 aa)

Score: 125 bits (313), Expect: 2.87483e-27
Length: 323, Idn/Pos/Gap = 95/149/15 (29%/46%/4%)

Query:  30 PRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYW------WHGSCGPFRLHDPMIIGH  83
           P++ R+    VP P P E+  Q+  VGIC  D+  +      W  +  P  +  PMI GH
Sbjct:  33 PQDYRLEQVPVPKPGPDEILTQVERVGICMGDIKTFRGAPSFWGDAVQPRYVKPPMIPGH  92

Query:  84 ESAGVVEALGAGVT--SLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFA-TPPVDG 140
           E    V ALG G     ++ GDRV  E  VPC  C+ C  G+Y +C     +     V G
Sbjct:  93 EFVCRVVALGPGAERRGVKAGDRVISEQIVPCWSCRFCGHGQYWMCQKHDLYGFQNNVHG 152

Query: 141 SLARY-VCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGL 199
           ++A Y +    A  +R+P+S+  +E  + EPLS ++HA  RA      +V+V GAG +GL
Sbjct: 153 AMAEYMIFTKEAIVHRVPDSIPTDEAILIEPLSCSLHAADRANVGFDDVVVVAGAGTLGL 212

Query: 200 LNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQA 259
                 +      ++V D+   R A A    GAD V N     E +    ++    G   
Sbjct: 213 GIIGAVRLRHPKQLIVLDMKPERAALAR-RMGADDVWNPA---EENVIEKIRAITGGYGC 268

Query: 260 DIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPL-VDASSREIDIFGVFRYSNT 318
           DI ++  G    +   + ++R  GR     + +    V   +    +E+D+ G       
Sbjct: 269 DIYIEATGHHRAVGQGLAMLRKLGRFVEFSVFNDEASVDWSIIGDRKELDVLGSHLGPYM 328

Query: 319 YPTCIALLASGRVNVKPLITHRF 341
           YP  I  +AS R++V+ ++TH F
Sbjct: 329 YPRAIEFIASRRIDVRGIVTHTF 351

emb|CAD13722.1| PROBABLE ZINC-DEPENDENT ALCOHOL DEHYDROGENASE OXIDOREDUCTASE PROTEIN [Ralstonia solanacearum]
ref|NP_518315.1| PROBABLE ZINC-DEPENDENT ALCOHOL DEHYDROGENASE OXIDOREDUCTASE PROTEIN [Ralstonia solanacearum GMI1000]
(345 aa)

Score: 124 bits (312), Expect: 3.57131e-27
Length: 348, Idn/Pos/Gap = 105/167/28 (30%/47%/8%)

Query:  34 RVMLRSVPAP---APGEVRLQMRCVGICGSDVHYWWHG--SCGPFRLHDPMIIGHESAGV  88
           ++ L + P P   APG+  +++    ICG+D+H       +C P R      +GHE  GV
Sbjct:  11 KISLENKPKPELQAPGDAVVRVTLTTICGTDLHIIKGDVPTCEPGR-----TLGHEGVGV  65

Query:  89 VEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCH 148
           +E++GA VTSL+ GD V +     C +C  CR G Y+ C    +     +DG  A YV  
Sbjct:  66 IESVGAAVTSLKPGDHVLISCISSCGKCANCRRGMYSHCETGGWILGHRIDGVQAEYVRV 125

Query: 149 PAAWC--YRLPESVSLEEGAMCEPL-----SVAVHANRRAGTTIGSLVLVLGAGPIGLLN 201
           P A    Y++P  V  E   M   +        V   R      GS V ++GAGPIGL +
Sbjct: 126 PHAETSLYKVPPGVDEEALVMLSDIFPTGFECGVLNGR---VQPGSTVAIVGAGPIGLAS 182

Query: 202 CMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADI 261
            + A+ +  + I++ D +  RL  A     +D +  TR+    +AA  V++  DG   D 
Sbjct: 183 LLTAQFYSPARIIMIDTNVARLEVASGLGASDCINVTRE----NAAAAVKRLTDGMGVDC 238

Query: 262 ALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPT 321
           A++  G+ +T  L   +V PGG I  +G+      + L    S+ I I      + + P 
Sbjct: 239 AIEAVGVPATFELCQELVAPGGVIANIGVHGVKADLHLETLWSQNIAITTRLVDTVSTPM 298

Query: 322 CIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANG-AVKVML 368
            +  + +G++    LITHRF   +   + AA++T R A    A+KV++
Sbjct: 299 LLKTVRAGKLLPGQLITHRF---KLDDILAAYDTFRNAGETHALKVII 343

ref|ZP_00006710.1| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Rhodobacter sphaeroides 2.4.1]
(337 aa)

Score: 124 bits (311), Expect: 3.9474e-27
Length: 311, Idn/Pos/Gap = 93/150/13 (29%/48%/4%)

Query:  33 LRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEAL  92
           LR+    +  P P EV +++    ICG+D H       G F    P+++GHE AG VE +
Sbjct:  12 LRLTDLPIQEPGPDEVLIRIDSATICGTDQHILE----GKFWAKPPVVLGHEFAGYVERV  67

Query:  93 GAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAW 152
           G  V + + GD V++EP V C  C+ CR G+ +LC + +      ++G   +Y       
Sbjct:  68 GERVQNCRPGDLVSVEPHVYCGCCKPCRLGKPHLCLD-RLAWGINLNGGFEQYATVRMDT 126

Query: 153 CYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASI 212
            Y++PE +  EE A+ E     +H   R G  +G LV++LG G  GL+   +A+  GA+ 
Sbjct: 127 VYQVPEGIGPEEAALGEITGCCMHGIDRVGVELGDLVVILGGGAAGLILARLAELRGAAR 186

Query: 213 IVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTM 272
           IV+++ +  R          D V    D    D A  +    DG  AD+ ++ AG   T 
Sbjct: 187 IVISEPNAARREQIRAFGYPDVV----DPLNEDLAARIGALTDGLGADVVIEAAGRAETA 242

Query: 273 RLAMHVVRPGGRICLVGMGSSAMHVPLVDAS--SREIDIFGVFRYSNTYPTCIALLASGR 330
             A+ +V  GGR+   G+ +      +      +REI + G  R   T+   + +L   R
Sbjct: 243 AQAVELVCHGGRVLFFGVAAPGTMAAIEPNRIFAREITVVGSIRNPYTHHRVMEILP--R 300

Query: 331 VNVKPLITHRF 341
           + +K ++THRF
Sbjct: 301 LRLKDIVTHRF 311

gb|AAL21957.1| putative zinc-binding dehydrogenase [Salmonella typhimurium LT2]
ref|NP_461998.1| putative zinc-binding dehydrogenase [Salmonella typhimurium LT2]
(338 aa)

Score: 124 bits (311), Expect: 3.98047e-27
Length: 261, Idn/Pos/Gap = 85/132/9 (32%/50%/3%)

Query:  30 PRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVV  89
           P  +  + R +P     EV L+++ VGICG+D+H +      PF  + P ++GHE  GV 
Sbjct:   9 PGNIEYIERDIPHLKDDEVLLKIKAVGICGTDIHAF--AGRQPFFAY-PRVLGHEICGVA  65

Query:  90 EALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHP 149
           E LG   ++ +VG R ++ P +PC  C  CREG+ N C N+  +     DG  + Y+   
Sbjct:  66 EMLGKSCSTAKVGQRYSVIPCIPCGACAACREGKTNCCENVSLYGVHQ-DGGFSEYLAVR 124

Query: 150 AAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFG 209
                 L ++++   GA+ E  +++ HA RRA       ++V+GAGPIGL    +AKA G
Sbjct: 125 EQNLVELSDNLTDSAGALVECFAISAHAVRRADVKPQQNIVVVGAGPIGLAAAAIAKAKG 184

Query: 210 ASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLE 269
           A  + V DID  R        G    + T D    D    ++    G  A   LD  G +
Sbjct: 185 AR-VAVADIDAERRRLVAEKVG----VATLDPSSDDYIDALKACFSGELAGTVLDATGNK 239

Query: 270 STMRLAMHVVRPGGRICLVGM 290
           S+M  A+ ++R GG+I  +G+
Sbjct: 240 SSMSRAVDLIRHGGKIVFIGL 260

ref|ZP_00006223.1| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Rhodobacter sphaeroides 2.4.1]
(341 aa)

Score: 124 bits (311), Expect: 4.18482e-27
Length: 334, Idn/Pos/Gap = 102/160/22 (30%/47%/6%)

Query:  38 RSVPAPAPGEVRLQMRCVGICGSDVHYW----WHGSCGPFRLHDPMIIGHESAGVVEALG  93
           R VP   P EV +++R  GICG+DVH W    W     P     P++ GHE AG +  +G
Sbjct:  18 RPVPEIGPDEVLIRVRKTGICGTDVHIWNWDDWAAKTVPV----PLVTGHEFAGEIVEVG  73

Query:  94 AGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWC 153
             V  L  G R + E  +     ++ R GR++L P  +      V G+ A Y+  PA   
Sbjct:  74 RDVRDLSPGQRCSGEGHLIGHHSRQVRAGRFHLDPETRGIGVN-VPGAFADYLRLPAFNV 132

Query: 154 YRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASII 213
             LP+++  E GA+ +PL  AVH    +   +G  VLV GAGPIG++   VA+  GA  +
Sbjct: 133 VPLPDAIDDEVGAILDPLGNAVHT-ALSFDLVGEDVLVTGAGPIGIMAAAVARHVGARHV 191

Query: 214 VVTDIDDRRLAFAETHAGADAV-INTRDLDEHDAALVVQQALDGAQADIALDCAGLESTM 272
           V+TD++  RL  +   A    V + T DL      L + Q       D+ ++ +G  +  
Sbjct: 192 VITDVNADRLRLSTEVADVVPVNVATEDLRSVMGRLKIVQGF-----DVGMEMSGAPAGF 246

Query: 273 RLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVF--RYSNTYPTCIALLASGR 330
              +  +  GGRI ++G+      V       + + I GV+      T+   IA+L +G 
Sbjct: 247 DQMVEAMVMGGRIAMLGIPPGRSPVDWSRIVFKALTIKGVYGREIFETWYKMIAMLENG- 305

Query: 331 VNVKPLITHRFMGLEESSLEAAFETARTAANGAV 364
           ++++ +ITHRF     +     F   R+ A+G V
Sbjct: 306 LDIRRVITHRF---PVADFAEGFAAMRSGASGKV 336

ref|NP_116829.1| putative dehydrogenase [Microscilla sp. PRE1]
gb|AAK62863.1| MS141, putative dehydrogenase [Microscilla sp. PRE1]
(339 aa)

Score: 124 bits (311), Expect: 4.21988e-27
Length: 306, Idn/Pos/Gap = 97/151/18 (31%/49%/5%)

Query:  40 VPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSL  99
           V  P PGEVRL +   G+CG+DVH + HG     R++ P  IGHE++ VV  +G GVT++
Sbjct:  19 VVVPGPGEVRLDVAYCGVCGTDVHIF-HGVMDK-RVNPPQTIGHEASAVVAEVGEGVTNV  76

Query: 100 QVGDRVALEP---GVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRL 156
           +VG +VA+ P   G P        +G  ++  N+KF      +G+       PA   ++L
Sbjct:  77 KVGYKVAVRPLRFGEP----HPFDKGHAHVGKNLKFIGIDS-EGAFQNSWTVPAYTLHQL 131

Query: 157 PESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVT 216
           P+ +SLE GA  EPL+VA H  +      G   LV+G GPIG L   V K  GA++I V+
Sbjct: 132 PDGLSLEHGAFIEPLAVACHDVKIGRVKSGENTLVIGGGPIGTLIAYVLKEKGANVI-VS 190

Query: 217 DIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAM 276
           ++++ RL        ++    T +  + +    + +  +    D A + +G    ++   
Sbjct: 191 EVNEARLKML-----SELGFQTINPLKENLVDRISELTEEKMIDCAFEVSGSAPGVKTMT 245

Query: 277 HVVRPGGRICLVGM-GSSAMHVPLVDASSREIDIFGVFRY-SNTYPTCIALLASGRVNVK 334
            VV   GRI +V + G     V L      EI++ G   Y  + Y   I + ASG +   
Sbjct: 246 EVVNVRGRIVMVAIHGGEPKPVDLFKFFWSEIELLGARLYEEDDYEEAIRIAASGNIPFS 305

Query: 335 PLITHR 340
            LIT +
Sbjct: 306 KLITSK 311

ref|ZP_00063188.1| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293]
(499 aa)

Score: 124 bits (311), Expect: 4.39965e-27
Length: 317, Idn/Pos/Gap = 99/156/18 (31%/49%/5%)

Query:  31 RELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSC-----GPFRL---HDPMIIG  82
           +++RV    +      EV +++   GICGSD+H +  G        P  L     P+ +G
Sbjct:  10 KDVRVEDVELKPTKSNEVVVRVAYAGICGSDLHEYLEGPVFIPVDQPDELTGGQAPLTMG  69

Query:  83 HESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSL 142
           HE +GV+E +G  V + +VGD V++ P V     +       ++     F      DG  
Sbjct:  70 HEFSGVIEKVGPDVANFKVGDHVSINPTV----TKGISSDDLDVYDGYSFIGLS-TDGGF 124

Query: 143 ARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNC 202
             YV  P    Y LPE  SL+  A  EP +VAV A + A    G  V++ GAGPIG+L  
Sbjct: 125 TSYVNVPEDNLYHLPEEFSLKLAATIEPTAVAVQAIKEADLRFGEKVVIFGAGPIGVLVA 184

Query: 203 MVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIA 262
             AKA GA+ IV  D+ + RL  A    GA  VIN   + +  AA  ++  + G  AD +
Sbjct: 185 AAAKAAGATKIVAVDLSEIRLRKA-LEMGATDVINPSQVPDTVAA--IKNIIPGG-ADAS 240

Query: 263 LDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSN-TYPT 321
            + AG++ T   A+   RP G + +V + +  +    +   +  + +     YS  T+  
Sbjct: 241 FEVAGVQPTFEQAIDATRPRGSVVIVSIFAKPISFNPMQLMNAGVKLTTTIAYSKETFQQ 300

Query: 322 CIALLASGRVNVKPLIT 338
            +AL++SG++NV+P+IT
Sbjct: 301 TVALVSSGQINVEPVIT 317

ref|NP_105878.1| 2,3-butanediol dehydrogenase [Mesorhizobium loti MAFF303099]
dbj|BAB51664.1| 2,3-butanediol dehydrogenase [Mesorhizobium loti MAFF303099]
(289 aa)

Score: 124 bits (311), Expect: 4.98624e-27
Length: 292, Idn/Pos/Gap = 104/144/10 (35%/49%/3%)

Query:  79 MIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPV 138
           M  GHE +G+VEA+G  V+   VGDRV  +P + C +C  C  GR NLC N+        
Sbjct:   1 MTPGHEFSGIVEAIGKAVSGFAVGDRVTGDPNIACGRCPHCHAGRVNLCRNLNAIGIHR-  59

Query: 139 DGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIG 198
           DG  A YV  P    + LP  +    GA CEPL   +H    A    GS V+VLG G IG
Sbjct:  60 DGGFAEYVVLPQKQAFILPADLPPTHGAFCEPLGCCLHGVDLAQIKPGSSVVVLGGGVIG 119

Query: 199 LLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQ 258
           LL   +AK  GA+ I+++     R   AE   GA A ++    D  DA    +  + G  
Sbjct: 120 LLTVQLAKLAGATTIILSTRQASRRVLAE-ELGATATVDPTAGDVIDAIAGSEGLMPGG- 177

Query: 259 ADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPL--VDASSREIDIFGVFRYS 316
           AD+  +CAG+  T+  +M + R GG + +VG+    M       D   RE+ + G F   
Sbjct: 178 ADVVFECAGVRDTVEQSMRLARAGGTVVIVGVTPQGMKAEFEPFDLLFRELKVVGSFLNP 237

Query: 317 NTYPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVML 368
            T+     L+ASG + +  LI+ R + LE    EAA   A   A G VKV++
Sbjct: 238 YTHRRAAELIASGAIEIDRLIS-RQVPLE----EAADVIANPPAPGEVKVLV 284

ref|ZP_00188536.2| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Rubrobacter xylanophilus DSM 9941]
(357 aa)

Score: 124 bits (310), Expect: 5.24222e-27
Length: 360, Idn/Pos/Gap = 121/167/43 (33%/46%/11%)

Query:  30 PRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVV  89
           PRELRV    VP   P +V +++   GICGSD+H +  G      +    I+GHE  G V
Sbjct:  15 PRELRVEPVPVPEIGPSDVLVRVHSCGICGSDLHSYKAG----MYIRPGQIMGHEFMGTV  70

Query:  90 EALGAGVTSLQVGDRV-ALEPGVPCLQCQRCREGRYNLCPNI-----------KFFATPP 137
            A G  V  ++ GDRV     GV C  C  C   +Y LCP +            F    P
Sbjct:  71 AAAGEDVEGVEEGDRVTGFSIGV-CGSCYWCSRQQYILCPELFRNSTGYGLPGGFAEYVP 129

Query: 138 VDGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPI 197
           +  ++     HP      +P  +  E  A  EP+SV V A   AG   G  V+VLGAG I
Sbjct: 130 IRNAVVGQSIHP------VPSELDDETAATTEPVSVGVGAIEAAGVRPGDRVVVLGAGMI 183

Query: 198 GLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQAL--- 254
           G      A+A GA  + V D+   RL  A +  GADAV + R  D    AL   + L   
Sbjct: 184 GNACMQAARAAGAGQVAVIDVSPVRLEAARS-LGADAVFDARTGD----ALSWVKELWGV 238

Query: 255 ------DGAQADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREID 308
                 +G  AD+ ++ AG   T++ A  +VR GG I  VG+      + +     ++  
Sbjct: 239 GRYHFNEGGMADVVVEAAGAPVTVQQAFEMVRSGGAIVFVGLPEEPAPIDVTKIVHKQPR 298

Query: 309 IFGVFRYSNTYPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVML 368
           I G       +   I L+ASG +  K LITHRF  LE+++   AFET +     A+KVM+
Sbjct: 299 IVGSL--GGDFARAIELMASGSIRTKELITHRF-PLEDAA--EAFET-QLRTGEAMKVMI 352

ref|NP_682226.1| sorbitol dehydrogenase [Thermosynechococcus elongatus BP-1]
dbj|BAC08988.1| sorbitol dehydrogenase [Thermosynechococcus elongatus BP-1]
(366 aa)

Score: 123 bits (309), Expect: 7.25834e-27
Length: 335, Idn/Pos/Gap = 107/157/28 (31%/46%/8%)

Query:  40 VPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSL  99
           +P  A  EV +++R VG+C SD+    +    P     P I GHE+AG + A+G  VT  
Sbjct:  35 IPEIAADEVLVRVRVVGLCQSDIKKIRYPLYEP-----PRIFGHETAGEIAAVGDAVTGW  89

Query: 100 QVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATP----PVDGSLARYVCHPA----- 150
           QVG RV +   +PC+ C  C    Y++C   K   T     P  G  A YV  P      
Sbjct:  90 QVGQRVVVMHHIPCMHCAYCLNENYSMCHVYKTVTTTAGFIPSGGGFAEYVKVPGHIVEH 149

Query: 151 AWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGA 210
                +P+ +S EE +  EP +  + A ++AG   G  VL+ GAGPIGL+  M+   FGA
Sbjct: 150 GGLIPIPDPISDEEASFVEPTNCCLKAVKKAGIAPGQTVLITGAGPIGLMFIMLVNLFGA 209

Query: 211 SIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLES 270
             I  TD+   R+A A+   GA A  + RD    D +  VQ    G   D++L     E 
Sbjct: 210 RAI-ATDLLPSRIAKAK-EVGAAAAFDARD---PDLSAKVQALTHGLGVDVSLLAVPSEK 264

Query: 271 TMRLAMHVVRPGGRICLVGMGSSAMHVPLVD--ASSREIDIFGVFRYSNTY---PTCIAL 325
               A+   R GG+I         + +PL       REID+ G   YS++Y        +
Sbjct: 265 AFFQALECTRKGGKILFFAEFPDEVEIPLNPNILYRREIDLMG--SYSSSYRLQSLACDI 322

Query: 326 LASGRVNVKPLITHRF--MGLEESSLEAAFETART 358
           + + R++VK L++ R+    L E+  +A   T  T
Sbjct: 323 IFNRRIDVKTLVSDRYPLSKLAEAVEQAVHPTPET 357

ref|ZP_00222362.1| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Burkholderia cepacia R1808]
(335 aa)

Score: 123 bits (308), Expect: 8.86757e-27
Length: 345, Idn/Pos/Gap = 105/161/24 (30%/46%/6%)

Query:  37 LRSVPAP---APGEVRLQMRCVGICGSDVHYWWHG--SCGPFRLHDPMIIGHESAGVVEA  91
           L   P P   +P +  +++    ICG+D+H       +C P R     ++GHE  GVVE 
Sbjct:   3 LEQRPKPELQSPTDAIVRVTRTTICGTDLHILKGDVPTCEPGR-----VLGHEGVGVVEQ  57

Query:  92 LGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAA 151
           +GA V +L+ GDRV +     C +C+ CR G Y+ C    +     +DG+ A YV  P A
Sbjct:  58 VGAAVDALKPGDRVLISCISSCGRCEYCRRGLYSHCTTGGWILGNRIDGTQAEYVRIPHA 117

Query: 152 WCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSL-----VLVLGAGPIGLLNCMVAK 206
                P     +E A+   LS  +      G   G +     V ++GAGPIGL   + A+
Sbjct: 118 QTSLYPIPAGADEDALVM-LSDILPTGFECGVLNGKVQPGCSVAIVGAGPIGLAALLTAQ 176

Query: 207 AFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCA 266
            +    I++ D D  RL  A      D V    D    DAA  V +  DG   D A++  
Sbjct: 177 FYSPGQIIMIDPDSNRLDIARRFGATDCV----DGRSGDAAADVMKLTDGIGVDCAIEAV 232

Query: 267 GLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALL 326
           G+ +T  L   +V PGG +  VG+      + L     R I I      + + P  +  +
Sbjct: 233 GIPATFELCTSIVAPGGVVANVGVHGVKADLHLEKLWDRNIAITTRLVDTVSTPMLLKTV 292

Query: 327 ASGRVNVKPLITHRFMGLEESSLEAAFET-ARTAANGAVKVMLTI 370
            +GR++   LITHRF  L++  +E A++T  R A   A+KV++ +
Sbjct: 293 RAGRLDPAQLITHRF-ALDD--VEGAYDTFGRAAQTHALKVIIEV 334

ref|YP_110851.1| zinc-binding dehydrogenase [Burkholderia pseudomallei K96243]
emb|CAH38302.1| zinc-binding dehydrogenase [Burkholderia pseudomallei K96243]
ref|YP_105447.1| alcohol dehydrogenase, zinc-containing [Burkholderia mallei ATCC 23344]
gb|AAU46874.1| alcohol dehydrogenase, zinc-containing [Burkholderia mallei ATCC 23344]
(346 aa)

Score: 123 bits (308), Expect: 9.47968e-27
Length: 349, Idn/Pos/Gap = 109/164/23 (31%/46%/6%)

Query:  34 RVMLRSVPAP---APGEVRLQMRCVGICGSDVHYWWHG--SCGPFRLHDPMIIGHESAGV  88
           R  L   P P   AP +V +++    ICG+D+H       SC P R     ++GHE  GV
Sbjct:  11 RKSLDERPMPELAAPTDVIVRVTRTTICGTDLHILKGDVPSCEPGR-----VLGHEGVGV  65

Query:  89 VEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCH 148
           V   G  V++ + GDRV +     C QC+ CR G Y+ C    +     +DG+ A YV  
Sbjct:  66 VHRAGGAVSTFKEGDRVLISCISSCGQCEYCRRGMYSHCATGGWILGNRIDGTQAEYVRI 125

Query: 149 PAAWC--YRLPESVSLEEGAM-CEPLSVAVHANRRAG-TTIGSLVLVLGAGPIGLLNCMV 204
           P A    YR+      E   M  + L          G    G  V ++GAGPIGL   + 
Sbjct: 126 PHAQTSLYRIAPGADEEALVMLSDILPTGFECGVLNGRVQPGGTVAIIGAGPIGLAALLT 185

Query: 205 AKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALD 264
           A+ +  + IV+ D D  RLA A    GA A I+   +D    A+   +AL G   D A++
Sbjct: 186 AQFYSPAQIVMIDPDPNRLALARRF-GATACIDNGQVD----AVAGVKALTGDGVDCAIE 240

Query: 265 CAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIA 324
             G+ ++  L   ++ PGG I  VG+      + L     R I I      +++ P  + 
Sbjct: 241 AVGIPASFELCQRIIAPGGVIANVGVHGMKADLHLETLWDRNITITTRLVDTSSTPMLLK 300

Query: 325 LLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANG-AVKVMLTIPE 372
            + +GR++ K LITHRF     + +  A+ET   AA+  A+KV++ + E
Sbjct: 301 TVGAGRLDPKQLITHRF---SLADIGQAYETFGHAAHTRALKVIVEVSE 346

dbj|BAB76816.1| alr5117 [Nostoc sp. PCC 7120]
ref|NP_489157.1| hypothetical protein alr5117 [Nostoc sp. PCC 7120]
pir||AE2445 hypothetical protein alr5117 [imported] - Nostoc sp. (strain PCC 7120)
(341 aa)

Score: 123 bits (308), Expect: 1.03046e-26
Length: 316, Idn/Pos/Gap = 94/152/18 (29%/48%/5%)

Query:  32 ELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEA  91
           +LR+   + P+P  GEV +++     CG+D+  W  G      L  P + GHE+AG + A
Sbjct:  11 DLRLEQVADPSPDVGEVVIKVGAATTCGTDLKVWRRGGHAKM-LKLPTLFGHEAAGEIVA  69

Query:  92 LGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAA 151
           +GA VT  Q+GDRV      PC++C  C+   Y+LCPN+ +      +G+ A Y+  PA 
Sbjct:  70 VGADVTGWQIGDRVVANNSAPCMKCFFCQRQEYSLCPNLTW-----NNGTFAEYLKIPAP 124

Query: 152 WC----YRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKA 207
                  ++P+ + L   AM EPL+  +H   R+       V+VLG G IGL+   VA  
Sbjct: 125 IVQHNLLQVPDELPLSLAAMTEPLACVLHGVARSHIKPQDRVVVLGDGAIGLM--FVAVL 182

Query: 208 FGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAG 267
                +++   +D+RL   +   GA    N       D   VV++   G  AD+ ++  G
Sbjct: 183 ADKVEVLLWGGNDQRLEIGQK-LGATKTFNYH--QNPDIPHVVKELTQGWGADVVIEATG 239

Query: 268 LESTMRLAMHVVRPGGRICLVG--MGSSAMHVPLVDASSREIDIFGVFRYSNTY-PTCIA 324
           + S    A+   RPG  + L G     + + V        E+ + GVF  +  Y    +A
Sbjct: 240 VPSVWETAIACARPGAIVNLFGGCPRDTTITVNTEQLHYSELTLKGVFHNTPEYVRAALA 299

Query: 325 LLASGRVNVKPLITHR 340
           L+AS ++  + LI+ +
Sbjct: 300 LIASRKIPFELLISEQ 315

ref|NP_923886.1| sorbitol dehydrogenase [Gloeobacter violaceus PCC 7421]
dbj|BAC88881.1| sorbitol dehydrogenase [Gloeobacter violaceus PCC 7421]
(360 aa)

Score: 122 bits (307), Expect: 1.2801e-26
Length: 350, Idn/Pos/Gap = 108/158/27 (30%/45%/7%)

Query:  32 ELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEA  91
           +LR     VP  A  EV +Q+R  G+C SD+    +    P     P I GHE++G +  
Sbjct:  23 DLRYEQVPVPEVAADEVLVQVRACGLCQSDIKKLRYPLLDP-----PRIFGHETSGTIVR  77

Query:  92 LGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFAT----PPVDGSLARYVC 147
            G  V   +VG+RV +   +PC  C  C    Y++C   K   T     P  G  A YV 
Sbjct:  78 AGEAVEHWRVGERVVVLHHIPCFHCPYCLNENYSMCRVYKEVTTTAGFAPAGGGFAEYVK 137

Query: 148 HP-----AAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNC 202
            P     +     +P+ VS EE +  EP +  + A ++A    G  VL+ GAGPIGL+  
Sbjct: 138 VPGHIVRSGGLMAIPDGVSFEEASFVEPTNCCLKAVKKAQVQPGQWVLITGAGPIGLMFA 197

Query: 203 MVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIA 262
           M+ + FGA  I VTD+   R+  A    GA+A ++ R     D    +     G   D+A
Sbjct: 198 MLCRQFGAKPI-VTDLLASRVERARA-LGAEAALDARSA---DLTARIHALTGGLGVDVA 252

Query: 263 LDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDAS---SREIDIFGVFRYSNTY 319
           L           A+   R GG+I      + ++ +PL D +    REID+ G +  S   
Sbjct: 253 LLAVPSVQAFSQALDATRKGGKILFFAEFAESVQIPL-DPNVLYRREIDLMGSYSSSFKV 311

Query: 320 PTCIALLASG-RVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVML 368
               A L  G R++V+ LI+  F  L E  L AA E A        K+++
Sbjct: 312 QHLAADLVFGRRIDVQALISD-FYPLAE--LAAAVEQAVHPTPETCKILI 358

ref|NP_436021.1| hypothetical protein SMa1417 [Sinorhizobium meliloti 1021]
gb|AAK65433.1| Putative [Sinorhizobium meliloti 1021]
pir||G95358 probable [imported] - Sinorhizobium meliloti (strain 1021) magaplasmid pSymA
(341 aa)

Score: 122 bits (307), Expect: 1.41491e-26
Length: 278, Idn/Pos/Gap = 87/133/15 (31%/47%/5%)

Query:  25 GVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHE  84
            VLV PR   V    +P   P +V +++   GICG+D+H + +G     RL  P++ GHE
Sbjct:   4 AVLVEPRRFEVREVGIPEIGPADVLIRVTRAGICGTDLHIF-NGHYAADRL--PIVPGHE  60

Query:  85 SAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLAR 144
             G +  +GA VT L+ G RV  +  + C  C  CR      C  ++       DG+ A+
Sbjct:  61 FCGTIAEIGASVTHLKTGMRVVADINIGCGNCYWCRRNEVLNCGEVEQIGIGR-DGAFAQ 119

Query: 145 YVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMV 204
           YV  P      +P+ V     A+ EP++  V A R+AG   G   +VLGAGPIG L+  +
Sbjct: 120 YVALPGRLVLPVPDGVPEAVLALVEPVACVVRAARKAGAAFGRSGVVLGAGPIGNLHVQM 179

Query: 205 AKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALD---GAQADI 261
            +  G + I+V D+   R   A   AGADA ++       + A +  + L+   G  AD 
Sbjct: 180 MRLVGMAPIIVADLSSERCRMA-VEAGADAAVS-------EPATLRSKVLEMTGGRGADF 231

Query: 262 ALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPL 299
            ++  G     R A  +VR GG +   G+      +P+
Sbjct: 232 VVESVGSSKLYRQAFDLVRKGGHVAFFGITPPGETIPI 269

emb|CAB61801.1| putative dehydrogenase [Streptomyces coelicolor A3(2)]
ref|NP_627680.1| putative dehydrogenase [Streptomyces coelicolor A3(2)]
(344 aa)

Score: 122 bits (307), Expect: 1.47519e-26
Length: 341, Idn/Pos/Gap = 107/166/21 (31%/48%/6%)

Query:  32 ELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEA  91
           ++RV    +P   PG   +++ C GICG+D+    HG     R    +I+GHE +G VE 
Sbjct:  15 DVRVEEVPMPEVPPGWALVRVACTGICGTDLGI-VHGKHP--RARQGLILGHEISGWVEV  71

Query:  92 LGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAA 151
              G      G  V  EP + C  C+ CREG  ++C  +  F      G+ A++V  P +
Sbjct:  72 TAPG--GPPEGALVVAEPLISCKDCRACREGHSHVCARLGLFGIDAPGGA-AQFVALPTS 128

Query: 152 WCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGAS 211
             +++P  V   + A+ EPL+VAVHA  R+G   G +V V GAGPIG+L  +VA+  GAS
Sbjct: 129 TLHQVPSRVEPTQAALTEPLAVAVHAVSRSGMEAGDVVAVFGAGPIGILTALVARHEGAS 188

Query: 212 IIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLEST 271
            +VV + + RR A A +  G  AV +   L +     +V +   G  AD   D A   + 
Sbjct: 189 HVVVAEPNARRRAVA-SDMGLIAVPDGAQLRD-----MVAELSQGDGADTTFDSAAHPAV 242

Query: 272 MRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNT-YPTCIALLASGR 330
                 V R  GR+ +VG+      V L     +E  + GV  Y+   + T I L+A   
Sbjct: 243 AAELADVTRVLGRVVIVGVYKEPAAVDLQAVCFKEQSVVGVRVYTREDFRTAIDLVAQNA 302

Query: 331 VNVK--PLITHRFMGLEESSLEAAFETARTAANGAVKVMLT 369
           + +   P+  + F       +  AF+ A T + G +KV+++
Sbjct: 303 LGLDRFPVSVYGF-----DRISDAFDAAATGS-GGLKVLIS 337

ref|ZP_00159385.1| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Anabaena variabilis ATCC 29413]
(341 aa)

Score: 122 bits (306), Expect: 1.52525e-26
Length: 316, Idn/Pos/Gap = 93/150/18 (29%/47%/5%)

Query:  32 ELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEA  91
           +LR+   + P+P  GEV +++     CG+D+  W  G      L  P + GHE+AG + A
Sbjct:  11 DLRLEQLADPSPEVGEVVIKVGAATTCGTDLKVWRRGGHAKM-LKLPTLFGHEAAGEIVA  69

Query:  92 LGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAA 151
           +GAGVT  Q+GDRV      PC++C  C+   Y+LCPN+ +      +G+ A Y+  PA 
Sbjct:  70 VGAGVTGWQIGDRVVANNSAPCMKCFFCQRQEYSLCPNLTW-----NNGTFAEYLKIPAP 124

Query: 152 WC----YRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKA 207
                  ++P+ + L   AM EPL+  +H   R+       V+VLG G IGL+   VA  
Sbjct: 125 IVQHNLLQIPDELPLPLAAMTEPLACVLHGVARSQIKPQDKVVVLGDGAIGLM--FVATL 182

Query: 208 FGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAG 267
                +++   +D+RL   +   GA    N       D    V+    G  AD+ ++  G
Sbjct: 183 ADNVEVLLWGGNDQRLEIGQK-LGAAKTFNYH--QNPDIPGTVKDLTQGWGADVVIEATG 239

Query: 268 LESTMRLAMHVVRPGGRICLVG--MGSSAMHVPLVDASSREIDIFGVFRYSNTY-PTCIA 324
           +      A+   RPG  + L G     + + V        E+ + GVF  +  Y    +A
Sbjct: 240 VPKVWETALACARPGAIVNLFGGCPRDTTITVNTEQMHYSELTLKGVFHNTPEYVRAALA 299

Query: 325 LLASGRVNVKPLITHR 340
           L+AS ++  + LI+ +
Sbjct: 300 LIASRKIPFELLISEQ 315

ref|NP_107492.1| alcohol dehydrogenase [Mesorhizobium loti MAFF303099]
dbj|BAB53278.1| alcohol dehydrogenase [Mesorhizobium loti MAFF303099]
(341 aa)

Score: 122 bits (306), Expect: 1.68588e-26
Length: 343, Idn/Pos/Gap = 106/161/17 (30%/46%/4%)

Query:  27 LVRPRELRVMLRSVPA-PAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHES  85
           L  P +LRV   + P  P PG V+L++   GICGSD+H +     G +    P   GHE 
Sbjct:   6 LYGPGDLRVEDVAPPGIPDPGWVKLRVDAAGICGSDLHNF---RTGQWISRSPSTAGHEL  62

Query:  86 AGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARY 145
            G V ALG GV ++ VGDRV  +    C +C +CR GR +LC ++ F      DG  A  
Sbjct:  63 TGTVTALGEGVDTVAVGDRVVADSRFWCEECVQCRAGRRHLCASLGFVGE-VCDGGFAEQ 121

Query: 146 VCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVA 205
           V  PA   + +  ++     AM EPL+VA+HA RR   T GS VLV+G GPIG L  ++ 
Sbjct: 122 VVLPARLLHVVDAALDERVAAMAEPLAVALHAVRRLPKTAGS-VLVVGCGPIGGLAALLL 180

Query: 206 KAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDC 265
               A  ++V D +  R A      GA  V   RD         +  A   A    A++ 
Sbjct: 181 SRSFAGTVLVADRNQARCARVARVTGATIVDLDRD--------AIAAATGYAPLLAAVEA 232

Query: 266 AGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIAL 325
            G  +     + V+  G  + +VG+    + +       REI + G   +++  P  + +
Sbjct: 233 TGSIAAFNQLLGVLDSGSAVAMVGIFHGRLDIDPNLLVEREIALLGCHAFADELPDAVRM 292

Query: 326 LASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVML 368
           L      +  LI  R +GL++  + AA+E      +  +K ++
Sbjct: 293 LGELSEPLLALID-REIGLDD--IPAAYERLLAGQSDGLKTII 332

dbj|BAB05670.1| BH1951 [Bacillus halodurans C-125]
ref|NP_242817.1| hypothetical protein BH1951 [Bacillus halodurans C-125]
pir||G83893 hypothetical protein BH1951 [imported] - Bacillus halodurans (strain C-125)
(408 aa)

Score: 122 bits (305), Expect: 2.29562e-26
Length: 368, Idn/Pos/Gap = 102/159/48 (27%/43%/13%)

Query:  35 VMLRSVPAPA-PGE--VRLQMRCVGICGSDVHYWW---HGSCGPFRLHDPMIIGHESAGV  88
           + LR V  PA P +  V ++++  GICGSD++  +     +  PF +  P  +GHE  G 
Sbjct:  35 LQLRDVEKPALPNDHWVEIKVKYGGICGSDLNLIFLNDSPATSPF-VSFPFTLGHEMVGT  93

Query:  89 VEALGAGVTSLQVGDRVALEPGVPCLQ------CQRCREGRYNLC---------PNIKFF 133
           +      VT+LQVG RV ++P + C        C  C  G YNLC         P +   
Sbjct:  94 ISKARKSVTNLQVGQRVVIDPLLSCEVRGITPVCSECANGNYNLCHHMNDGDIAPGLLTG 153

Query: 134 ATPPVDGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLG 193
                 GS  RY+    +    LP SV  + G + EP + A+HA  +        V V+G
Sbjct: 154 TCKDTGGSWGRYLVAHQSQVISLPSSVDDDNGVLVEPFACALHAVLQNRPKPSDTVFVIG 213

Query: 194 AGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAAL----- 248
           +G IG+      +A      +VT       A      GAD ++      ++  A+     
Sbjct: 214 SGVIGICVIAAIRALEIPCKIVTLAKHPFQAELAKQFGADEIVFLSRKRDYVTAVAESFN 273

Query: 249 ------VVQQALDGAQADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDA 302
                 V  + +    ADI  +C G   ++  ++   R GG++ L+G+ S   ++ +   
Sbjct: 274 ANVLHPVFGEPIVHGGADIVYECVGNRKSLHDSLRFARKGGKVVLIGLASFIDNLDMTMI 333

Query: 303 SSREIDIFGVFRY---------SNTYPTCIALLASGRVNVKPLITHRFMGLEESSLEAAF 353
              E+++ G F Y           T    + L+A G+V++ PLITHRF       LEA  
Sbjct: 334 WLNELEVKGSFTYGMEDWQGGKKRTLQIAVDLIADGKVDLSPLITHRF------PLEAYR 387

Query: 354 ETARTAAN 361
           E   TAAN
Sbjct: 388 EALATAAN 395

ref|ZP_00337079.1| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Silicibacter sp. TM1040]
(329 aa)

Score: 122 bits (305), Expect: 2.45408e-26
Length: 328, Idn/Pos/Gap = 100/161/14 (30%/49%/4%)

Query:  40 VPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSL  99
           VP   P EV +++   GICG+D+H W         +  PMI GHE AG +  LG  VT L
Sbjct:   6 VPEIGPDEVLIKINKTGICGTDIHIWNWDDWAAHTVPVPMITGHEFAGEIVELGRNVTGL  65

Query: 100 QVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPES 159
            VG R + E  +   + ++ R G+++L P  +        G+ A+Y+  PA     LP+ 
Sbjct:  66 TVGQRCSGEGHLIGTESRQSRSGKFHLDPGTRGIGVNE-QGAFAQYLRLPAFNVVPLPDD 124

Query: 160 VSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDID 219
           +  + GA+ +PL  AVH    +   +G  VL+ GAGPIG++   VA+  GA  +V+TD++
Sbjct: 125 IPDDIGAILDPLGNAVHT-ALSFDLLGEDVLITGAGPIGIMAAAVARHAGARHVVITDVN 183

Query: 220 DRRLAFAETHAGADAV-INTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHV 278
             RLA A        V +   DL++    L +++       D+ L+ +G +  +   +  
Sbjct: 184 ADRLALASEVTRVRTVNVAVEDLNDVMHELGLREGF-----DVGLEMSGNQQALDQMVEA 238

Query: 279 VRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVF--RYSNTYPTCIALLASGRVNVKPL 336
           +  GG+I L+G+      V       + I I GV+      T+   IA+L +G ++V  +
Sbjct: 239 LVMGGKIALLGIPPGKSPVDWSRIVFKAITIKGVYGREMFETWYKMIAMLQNG-LDVSGV 297

Query: 337 ITHRFMGLEESSLEAAFETARTAANGAV 364
           ITHRF   E    E  F   ++  +G V
Sbjct: 298 ITHRFAVDE---FEQGFAAMKSGQSGKV 322

dbj|BAD07386.1| putative dehydrogenase [Actinoplanes sp. A40644]
(340 aa)

Score: 121 bits (304), Expect: 2.58007e-26
Length: 350, Idn/Pos/Gap = 109/156/24 (31%/44%/6%)

Query:  27 LVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPF---RLHDPMIIGH  83
           +V P  L+     VP P PG V +  R  GICG+D+  + HG+       R   P+I GH
Sbjct:   6 IVGPGRLKTASVPVPEPLPGTVLVAPRYAGICGTDLELF-HGTSSYLADGRAATPLIFGH  64

Query:  84 ESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLA 143
           E  G V +   G T  + GDRVA +  VPC  C RCR GR  LC  ++      +DG+ A
Sbjct:  65 EWCGRVVSADPG-TGWRPGDRVAGQTMVPCGGCARCRAGRRGLCRRMREVGLYGLDGAAA 123

Query: 144 RYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCM 203
           +Y+  P     RLP++V     A+ EP    V +  R G      V VLG G IGLL   
Sbjct: 124 QYIRVPGHALARLPDTVPDRTAALVEPAVTVVESFARTGCGFDDRVAVLGTGTIGLLAVQ 183

Query: 204 VAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIAL 263
            A+     +  V  +D   LA A    GAD  I   +      +LVV+            
Sbjct: 184 FARRVAGRVDAV-GVDPAGLALA-VRCGADRAIPVGETTAGSYSLVVE------------ 229

Query: 264 DCAGLESTMRLAMHVVRPGGRICLVGMGSS-AMHVPLVDASSREIDIFGVFRYSNTYPTC 322
             +G       A+ +V PGGR+ ++G+ +     V     + R + + G+    + Y   
Sbjct: 230 -ASGAPEAFAHALDLVEPGGRVGVIGVANEPTAGVVAGSVALRGVSVLGIQHGLDHYDRT 288

Query: 323 IALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLTIPE 372
           I L A+G +   PLI   F     +   A  E+AR+   G  KV+L + E
Sbjct: 289 IELFATGALTADPLIGATFPAGAAAEAFAFMESARS---GPPKVLLDLTE 335

ref|NP_394213.1| sorbitol dehydrogenase related protein [Thermoplasma acidophilum DSM 1728]
emb|CAC11883.1| sorbitol dehydrogenase related protein [Thermoplasma acidophilum]
(250 aa)

Score: 121 bits (304), Expect: 3.09993e-26
Length: 263, Idn/Pos/Gap = 85/125/21 (32%/47%/7%)

Query:  38 RSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDP-MIIGHESAGVVEALGAGV  96
           R +  P PG V +++   GICGS++  +     G   L  P  I+GHE  G V  +G+  
Sbjct:   6 RPLEEPQPGWVTVRVNYAGICGSELSAF----VGQNELRKPPSIMGHEFTGKVVKVGSSS  61

Query:  97 TSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRL 156
            S  +G  VA+ P V C +C+ C+ G   LCP  K        G    YV  P+  CY +
Sbjct:  62 DSNLLGKNVAVNPLVTCGKCRYCKTGNRQLCPERKLIGVD-YPGGFEEYVNVPSYSCYEI 120

Query: 157 PESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVT 216
            E     EG++ EPL+ A  A   A   +    LV+GAG IGLL+  + + +G    VVT
Sbjct: 121 TEK---PEGSLAEPLATAFRAINHAKPEMDDRALVIGAGTIGLLSAKLLELYGTVERVVT 177

Query: 217 DIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAM 276
           DI+D RL  A  H GA   IN +           ++       DI +D  G + T  +A+
Sbjct: 178 DINDYRLEHA-LHWGATRTINNK-----------KEKSIPKDFDIVIDAVGTQETRTMAI 225

Query: 277 HVVRPGGRICLVGMGSSAMHVPL 299
           + +  GGR+  VG+      +P+
Sbjct: 226 NSIARGGRVVFVGLHEPNAEMPV 248

ref|NP_757848.1| alcohol dehydrogenase [Mycoplasma penetrans HF-2]
dbj|BAC44252.1| alcohol dehydrogenase [Mycoplasma penetrans HF-2]
(364 aa)

Score: 121 bits (303), Expect: 3.54266e-26
Length: 336, Idn/Pos/Gap = 96/164/36 (28%/48%/10%)

Query:  26 VLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHES  85
           V V   +++++ + +P   P +  +++    ICG+D+H       G + +   + IGHE+
Sbjct:  14 VFVEKNKIQIVNKPIPTVGPNDALIKVTTTTICGTDIHI----VKGEYPVKPGLTIGHEA  69

Query:  86 AGVVEALGAGVTSLQVGDRV---ALEPG---VPCLQCQRCREG---RYNLCPNIKFFATP 136
            G++ A+G  VT  ++G+RV   A+ P      C   Q  ++G   +Y   P   +    
Sbjct:  70 VGILAAVGDEVTGFELGERVLAGAITPSGYTAACQSGQSSQDGIGTKYGYKPTAGWKFGN 129

Query: 137 PVDGSLARYVC--HPAAWCYRLPESVSLEEGAMC-EPLSVAVHANRRAGTTIGSLVLVLG 193
            +DG  A YV   +  A   R+P +++ E+  MC + +S        A   +G  V V+ 
Sbjct: 130 IMDGCQAEYVLVKNAMANLARVPNALTDEQVLMCPDIMSTGFSGPENANIKLGDYVGVIA 189

Query: 194 AGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQA 253
            GPIGL     AK  GASII+  D +DRRL  A+   GA   IN R++   D    V + 
Sbjct: 190 QGPIGLCATTGAKLMGASIIIAIDGNDRRLEIAK-ELGATHTINFRNV---DVVQEVNRI 245

Query: 254 LDGAQADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVF 313
            DG   D A++C G +ST      ++R GG +  +G+ SS + +PL DA +      G+ 
Sbjct: 246 TDGRMLDSAIECLGSQSTFEQGFRLLRAGGTLSSLGVYSSDIKLPL-DALAA-----GLG 299

Query: 314 RYSNTYPTC----------IALLASGRVNVKPLITH 339
            +  ++  C          ++L+ + RV+++ L+TH
Sbjct: 300 DHKISFALCPGGSERMRRLMSLIENKRVDLRSLVTH 335

gb|AAT92749.1| YAL061W [Saccharomyces cerevisiae]
sp|P39713|YAG1_YEAST Hypothetical zinc-type alcohol dehydrogenase-like protein in GDH3-CNE1 intergenic region
gb|AAC04973.1| Yal061wp [Saccharomyces cerevisiae]
ref|NP_009340.1| Yal061wp [Saccharomyces cerevisiae]
(417 aa)

Score: 121 bits (303), Expect: 3.81894e-26
Length: 357, Idn/Pos/Gap = 102/156/37 (28%/43%/10%)

Query:  44 APGEVRLQMRCVGICGSDVHYWWHGSCGPFRL----------HDPM--IIGHESAGVVEA  91
           AP E+ + +   GICG+D+H +   + GP             H+P+   +GHE AG V  
Sbjct:  25 APDELVIDIEWCGICGTDLHEY---TDGPIFFPEDGHTHEISHNPLPQAMGHEMAGTVLE  81

Query:  92 LGAGVTSLQVGDRVALEPGVPCLQ--------------CQRCREGRYNLCPNIKFFATPP 137
           +G GV +L+VGD+V +EP   C                C  C++G YN+C  +       
Sbjct:  82 VGPGVKNLKVGDKVVVEPTGTCRDRYRWPLSPNVDKEWCAACKKGYYNICSYLGLCGAGV 141

Query: 138 VDGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPI 197
             G  A  V    + CY++P+ V L+  A+ +PL+V  HA R      GS  L++GAGPI
Sbjct: 142 QSGGFAERVVMNESHCYKVPDFVPLDVAALIQPLAVCWHAIRVCEFKAGSTALIIGAGPI 201

Query: 198 GLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGA 257
           GL   +   A G   IVV++    R   AE   GA     T    +     +   A  G 
Sbjct: 202 GLGTILALNAAGCKDIVVSEPAKVRRELAEK-MGARVYDPTAHAAKESIDYLRSIADGGD 260

Query: 258 QADIALDCAGLESTMRLAMHVVR-PGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYS 316
             D   DC+GLE T+  A+  +   G  + L   G   +    +D +  E    G   Y+
Sbjct: 261 GFDYTFDCSGLEVTLNAAIQCLTFRGTAVNLAMWGHHKIQFSPMDITLHERKYTGSMCYT 320

Query: 317 -NTYPTCIALLASGRVNV---KPLITHRFMGLEESSLEAAFETARTAANGAVKVMLT 369
            + +   I  L  GR+++   + +IT R     E  L+ A           +K++LT
Sbjct: 321 HHDFEAVIEALEEGRIDIDRARHMITGRVN--IEDGLDGAIMKLINEKESTIKIILT 375

ref|ZP_00091009.2| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Azotobacter vinelandii]
(355 aa)

Score: 121 bits (303), Expect: 4.04863e-26
Length: 360, Idn/Pos/Gap = 104/160/27 (28%/44%/7%)

Query:  25 GVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHE  84
            + V P  + +  + +P   P +  +++    ICG+DVH       G + +   + IGHE
Sbjct:   5 AMFVEPGRIELQDKPIPDVGPDDALVRITTTTICGTDVHILK----GEYPVASGLTIGHE  60

Query:  85 SAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPP------- 137
             G+VE LG+ V     G RV      P      C++G  +           P       
Sbjct:  61 PVGIVEKLGSNVKGYSEGQRVIAGAICPSFTSYACQDGYPSQDGGCACHGYKPMGGWRFG 120

Query: 138 --VDGSLARYVCHPAAWC--YRLPESVSLEEGAMC-EPLSVAVHANRRAGTTIGSLVLVL 192
             +DG+ A YV  P A      +P+ +S EE  MC + +S        A   IG +V V 
Sbjct: 121 NSIDGTQAEYVLVPDAQANLAPVPDGLSDEEVLMCPDIMSTGFAGAEAANIRIGDIVAVF 180

Query: 193 GAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQ 252
             GPIGL     AK  GAS I+  D  D RL  A    GAD  +N R +D  D  L   +
Sbjct: 181 AQGPIGLCATAGAKLRGASTIIAIDGVDERLEIAR-RLGADVTLNFRKVDVVDEIL---R 236

Query: 253 ALDGAQADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPL----VDASSREID 308
              G   D +++  GL+ST   A+ V++PGG +  +G+ SS + +PL           I 
Sbjct: 237 LTGGRGVDASIEALGLQSTFESALRVLKPGGALSSLGVYSSDLTIPLGAFHAGLGDNRIV 296

Query: 309 IFGVFRYSNTYPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVML 368
                         + ++ASGRV++KPL+TH++       +EAA++      +G +KV +
Sbjct: 297 TSLCPGGKERMRRLLNVVASGRVDLKPLVTHQY---RLDDIEAAYDLFAHQRDGVLKVAI 353

ref|ZP_00276487.1| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Ralstonia metallidurans CH34]
(357 aa)

Score: 120 bits (302), Expect: 4.86439e-26
Length: 362, Idn/Pos/Gap = 101/170/39 (27%/46%/10%)

Query:  30 PRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVV  89
           P ++ +  + +PA  P +  +++    ICG+D+H       G + +   + IGHE  G++
Sbjct:  12 PGKIVLQEKPIPAVGPTDALIRITTTTICGTDIHILK----GEYPVERGLTIGHEPVGII  67

Query:  90 EALGAGVTSLQVGDRVALEPGVPCLQCQRCREG-----------RYNLCPNIKFFATPPV 138
           E LG+GVT    G RV      P      C++G            Y      +F  T  +
Sbjct:  68 EKLGSGVTGYHEGQRVIAGAICPSFYSYACQDGCASQDGQGHSHGYKPMGGWRFGNT--I 125

Query: 139 DGSLARYVCHPAAWC--YRLPESVSLEEGAMC-EPLSVAVHANRRAGTTIGSLVLVLGAG 195
           DG+ A YV  P A      +P+ ++ E+  MC + +S        A   IG +V V   G
Sbjct: 126 DGTQAEYVLVPDAQANLAPIPDGLTDEQVLMCPDIMSTGFSGAEHANIKIGDIVAVFAQG 185

Query: 196 PIGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQAL- 254
           PIGL     A+  GAS+I+  D  D RL  +    GAD  +N R+ D      VVQ+ L 
Sbjct: 186 PIGLCATAGARLRGASLIIAVDGIDDRLNISR-QMGADVTLNFRNTD------VVQEILR 238

Query: 255 --DGAQADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGV 312
              G   D +++  G ++T   A+ V++PGG +  +G+ SS + +PL DA +  +    +
Sbjct: 239 ITGGRGVDASIEALGTQATFESALRVLKPGGTLSSLGVYSSDLKIPL-DAFAAGLGDHRI 297

Query: 313 FRY-----SNTYPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVM 367
                          + ++ + R+++ PL+THRF   + + +EAA++      +G +KV 
Sbjct: 298 ITSLCPGGKERMRRLMNVIETQRIDLGPLVTHRF---KLADIEAAYDLFGHQRDGVLKVA 354

Query: 368 LT 369
           +T
Sbjct: 355 IT 356

emb|CAB13572.1| threonine 3-dehydrogenase [Bacillus subtilis subsp. subtilis str. 168]
ref|NP_389581.1| threonine 3-dehydrogenase [Bacillus subtilis subsp. subtilis str. 168]
pir||C69721 L-threonine 3-dehydrogenase (EC 1.1.1.103) - Bacillus subtilis
sp|O31776|TDH_BACSU L-threonine 3-dehydrogenase
(347 aa)

Score: 120 bits (302), Expect: 5.15696e-26
Length: 334, Idn/Pos/Gap = 98/164/14 (29%/49%/4%)

Query:  36 MLRSVPAPA--PGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALG  93
           +L  VP P     EV ++++   ICG+DVH +        R+  P + GHE +G+VE +G
Sbjct:  19 VLTEVPIPEIDKHEVLIKVKAASICGTDVHIYNWDQWARQRIKTPYVFGHEFSGIVEGVG  78

Query:  94 AGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWC 153
             V+S++VG+ V+ E  + C +C  C  G+ ++C N          G  A YV  PA   
Sbjct:  79 ENVSSVKVGEYVSAETHIVCGECVPCLTGKSHVCTNTAIIGVDTA-GCFAEYVKVPADNI 137

Query: 154 YRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASII 213
           +R P  +     ++ EPL  AVH    +    G    V+G GPIGL+   VAKA GAS +
Sbjct: 138 WRNPADMDPSIASIQEPLGNAVHTVLESQPA-GGTTAVIGCGPIGLMAVAVAKAAGASQV 196

Query: 214 VVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMR 273
           +  D ++ RL  A+   GA   ++   +++ D   +V     G  AD+  + +G  S + 
Sbjct: 197 IAIDKNEYRLRLAK-QMGATCTVS---IEKEDPLKIVSALTSGEGADLVCEMSGHPSAIA 252

Query: 274 LAMHVVRPGGRICLVGMGSSAMHVPLVDASS-REIDIFGVF--RYSNTYPTCIALLASGR 330
             + +   GGR  ++ +    + + L +    + + I G+   +  +T+     L++S  
Sbjct: 253 QGLAMAANGGRFHILSLPEHPVTIDLTNKVVFKGLTIQGITGRKMFSTWRQVSQLISSNM 312

Query: 331 VNVKPLITHRFMGLEESSLEAAFETARTAANGAV 364
           +++ P+ITH+F  LEE   E  FE  R+   G V
Sbjct: 313 IDLAPVITHQF-PLEE--FEKGFELMRSGQCGKV 343

ref|ZP_00378765.1| COG1062: Zn-dependent alcohol dehydrogenases, class III [Brevibacterium linens BL2]
(363 aa)

Score: 120 bits (301), Expect: 5.99266e-26
Length: 351, Idn/Pos/Gap = 103/157/29 (29%/44%/8%)

Query:  25 GVLVRPRELRVMLRSV--PAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIG  82
           GV+ R +   V L  +  P P PGEV + ++  G+C +D HY   G    +    P ++G
Sbjct:   7 GVISRSKGAPVELTDIVIPDPGPGEVIVDVKSCGVCHTDFHYREGGISDDY----PFLLG  62

Query:  83 HESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLC------------PNI 130
           HESAG V  +G GVT ++VGD V L     C +C+ C+ G    C            P+ 
Sbjct:  63 HESAGTVSEIGEGVTDVEVGDFVILNWRAICGECRACKRGEPWYCFDTHNASQKMTLPDG 122

Query: 131 KFFATPPVDGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAG-TTIGSLV 189
                    GS A      A  C ++PE+     G +   +   + A    G  T G  V
Sbjct: 123 TELEAALGIGSFAEKTLVAAGQCTKVPEADPAVVGLLGCGVMAGIGAAINTGEVTRGKSV 182

Query: 190 LVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALV 249
            V+G G +G      +   GA  I+  D+DD++L +A+   GA   +NTR   E +    
Sbjct: 183 AVIGCGGVGCSAIAGSALAGAGTIIALDLDDKKLDWAKD-LGATHTVNTRGKSEDEVVEA 241

Query: 250 VQQALDGAQADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMH--VPLVDASSR-- 305
           +Q+   G  AD+ +D  G   T R A +     G + LVG+ +  M   VPL+D   R  
Sbjct: 242 IQELTGGFGADVVIDAVGRPETWRQAFYGRDLAGTVVLVGVPTPEMELSVPLLDVFGRGG 301

Query: 306 --EIDIFGVFRYSNTYPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFE 354
             +   +G       +P  + L   GRV ++  ++ R +GL    +E AFE
Sbjct: 302 RLKSSWYGDCLPERDFPMLVDLYQQGRVPLEKFVSER-IGL--GDVEEAFE 349

gb|AAV93911.1| sorbitol dehydrogenase, putative [Silicibacter pomeroyi DSS-3]
ref|YP_165856.1| sorbitol dehydrogenase, putative [Silicibacter pomeroyi DSS-3]
(332 aa)

Score: 120 bits (301), Expect: 6.5687e-26
Length: 352, Idn/Pos/Gap = 114/161/51 (32%/45%/14%)

Query:  37 LRSVPAP--APGEVRLQMRCVGICGSDVH-YWWHGSCGPFRLHDPMIIGHESAGVVEALG  93
           LR +P P   PGE  +++  VGICGSD+H Y  H +  P     P+I+GHE AGV+    
Sbjct:  14 LREMPNPVAGPGEQLIRIARVGICGSDMHAYLGHDARRP----APLILGHEVAGVI----  65

Query:  94 AGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWC 153
             V   + G+RV + P V C  C  CREGR NLCP  +  + PP +G  A YV  P    
Sbjct:  66 --VGGPRDGERVTVNPLVTCGACPACREGRDNLCPTRQIISMPPREGGFAEYVAMPEGNL 123

Query: 154 YRLPESVSLEEGAMCEPLSVAVHANR-----RAGTTIGSLVLVLGAGPIGLLNCMVAKAF 208
             +P+SV L + A+ EPL+   H  R      +G    +LVL  GA  +G   C+ A+  
Sbjct: 124 VTVPDSVPLAQAALAEPLACGWHTVRLSLAALSGARDTALVLGGGAIGLGAALCLTAQ-- 181

Query: 209 GASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALD----GAQADIALD 264
           G   + V + +  R A+     G                   Q ALD    G+Q D+ +D
Sbjct: 182 GVPQVTVVEPNPARRAYLSDRCG-------------------QHALDTPPAGSQYDLVID 222

Query: 265 CAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRY-SNTYPTCI 323
             G  +T   A   VRPGG I  +G+G     + +   + +EI   G + Y S  +    
Sbjct: 223 GVGYAATRATASAHVRPGGVIGHIGLGEDTGGLDIRRMTLQEITFIGTYTYTSEDFRQTA 282

Query: 324 ALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVML---TIPE 372
             +  GR+   PL       L++ +  AAF   R     A KV+L   T PE
Sbjct: 283 QAIFDGRLG--PLDWTEARPLDQGA--AAFADIRAGRVAAPKVLLVPDTAPE 330

ref|NP_693737.1| dehydrogenase [Oceanobacillus iheyensis HTE831]
dbj|BAC14771.1| dehydrogenase [Oceanobacillus iheyensis HTE831]
(338 aa)

Score: 120 bits (300), Expect: 9.01941e-26
Length: 338, Idn/Pos/Gap = 93/153/16 (27%/45%/4%)

Query:  30 PRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVV  89
           P+ +       P    G   ++    GICGSD+  +      P R   P+++GHE +G +
Sbjct:   9 PKNILFQNNRKPTITKGWAIIKTSYAGICGSDLSIF--AGVHP-RAEAPLVMGHEFSGTI  65

Query:  90 EALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHP 149
           E    G  +L+ G RV + P + C +C  C+ G  ++C N+K       DG +  YV  P
Sbjct:  66 EE---GHPTLKKGTRVTVNPLLRCGECYPCQNGYSHVCENLKLVGID-CDGGMGEYVKVP 121

Query: 150 AAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFG 209
                 L +++S++ GA+ EP++VAVHA R+     G  V++ GAG IGL   +  +++G
Sbjct: 122 IHSIVPLKDNISMKLGALIEPVAVAVHAIRQGNYMPGDSVVIFGAGTIGLCVALTLRSYG 181

Query: 210 ASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLE 269
           A  +++ + +  RL  A+          T D    +    + +  D   AD   DCAG  
Sbjct: 182 AKNLIIVEPNKLRLEKAKQLG-----FQTLDPLSENVTEKIVEGTDNIGADYVFDCAGHP 236

Query: 270 STMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASG 329
           S +     VVR  G I +V M      + +     +E++I  V  Y++        L   
Sbjct: 237 SVVEAITEVVRVRGNIVIVAMYKQPPTLDMRQGMFKELNIQFVRVYTDKDFQIAIDLVDN 296

Query: 330 RVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVM 367
               + +ITH    L+    +  F+   T  + AVKVM
Sbjct: 297 HKEYEDIITHV---LQPEEAQKGFDLLTTHTD-AVKVM 330

ref|NP_969603.1| putative alcohol dehydrogenase I [Bdellovibrio bacteriovorus HD100]
emb|CAE80596.1| putative alcohol dehydrogenase I [Bdellovibrio bacteriovorus HD100]
(332 aa)

Score: 120 bits (300), Expect: 9.48243e-26
Length: 282, Idn/Pos/Gap = 94/144/26 (33%/51%/9%)

Query:  30 PRELRVMLRSVPAPAPG--EVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAG  87
           P +  + L  VP P PG  +V L++R  GIC SD+H   HG   P++  +   +GHE+ G
Sbjct:   8 PGKKELSLVEVPKPTPGPLDVILKIRAAGICHSDLHVL-HGEV-PYK--ESFTMGHEACG  63

Query:  88 VVEALGAGV-TSLQVGDRVALEPGVPCLQCQRCREGRYNLC--PNIKFFATPPVDGSLAR 144
            V   G+ V  +   GD  A+    PC  C  CR G  NLC  P+  F      DG+ A 
Sbjct:  64 EVVEKGSEVFGTFNPGDLYAVHGPNPCGHCNYCRTGHDNLCNDPSRTFIGLGQ-DGAYAE 122

Query: 145 YVCHPAAWCYRLPESVSLEEGAMC-EPLSVAVHANR-RAGTTIGSLVLVLGAGPIGLLNC 202
           Y+  PA    ++P+ +S E  A+  + +    HA + + G  +GS VL +G G +G+   
Sbjct: 123 YLKVPARNIVKVPKGISPEVAAVATDAVLTPYHAIKTKGGVGLGSKVLAIGLGGLGMNGV 182

Query: 203 MVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIA 262
            +A A GA +  V D+ D  L  A++  G   V+N++ +           +L     D+ 
Sbjct: 183 QIALALGAEVTAV-DLKDANLETAKSF-GVQKVLNSKQI----------SSLTPLSFDVV 230

Query: 263 LDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASS 304
           +D  GLEST + A + V+PGG I L+G+GS+   VPL  A++
Sbjct: 231 VDFVGLESTFKDAQNFVKPGGTILLIGLGSA--QVPLTTATA 270

ref|YP_055111.1| threonine 3-dehydrogenase [Propionibacterium acnes KPA171202]
gb|AAT82153.1| threonine 3-dehydrogenase [Propionibacterium acnes KPA171202]
(345 aa)

Score: 119 bits (299), Expect: 1.03939e-25
Length: 347, Idn/Pos/Gap = 108/172/22 (31%/49%/6%)

Query:  27 LVRPR-ELRVMLRSVPAP--APGEVRLQMRCVGICGSDVHY-WWHGSCGPFRLHDPMIIG  82
           LV+ R E  + L  VP P   P +V +++   GICG+DVH   W G      +H P+++G
Sbjct:   4 LVKTRPEPGLELVEVPDPVAGPNDVIVKVMRTGICGTDVHIDKWDGWAAK-TVHTPLVLG  62

Query:  83 HESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSL 142
           HE  G +  LG+ V  L+VG  V+ E    C +C+ C  G+ +LC N +      V+G+ 
Sbjct:  63 HEFCGEIVELGSEVNDLEVGQFVSGEGHYVCGRCRACLAGKRHLCRNTQGIGY-AVNGAY 121

Query: 143 ARYVCHPAA--WCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLL 200
            +Y   PA   W + +P+ +  +  A+ +P   AVH   +    +   VLV GAGPIG++
Sbjct: 122 CQYFVMPAGNVWVHHIPD-LDPDVAAIFDPFGNAVHTALQF-PCLAEDVLVSGAGPIGIM 179

Query: 201 NCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQA- 259
             +VA+  GA  +VVTD+ D RL  A+     +AV  +R+  E      V    D  +  
Sbjct: 180 AALVAQFQGARNVVVTDLSDERLELAQQLGLKNAVNVSREGLE-----TVWDRFDMKEGF 234

Query: 260 DIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVF--RYSN 317
           DI L+ +G  + +   +  +  GGRI L+G  S+ + +         I I GV   +   
Sbjct: 235 DIGLEMSGSGTALTSMIDNMTHGGRIALLGTPSTDITLDFSKIIFNMITIQGVTGRQIFE 294

Query: 318 TYPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAV 364
           T+ T  +L+ SG +++  +IT R+   E      AF+ A +   G V
Sbjct: 295 TWYTMASLIRSG-LDISGIITDRYPITE---FREAFDVAGSGHGGKV 337

ref|ZP_00159058.2| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Anabaena variabilis ATCC 29413]
(356 aa)

Score: 119 bits (299), Expect: 1.19779e-25
Length: 314, Idn/Pos/Gap = 96/148/22 (30%/47%/7%)

Query:  40 VPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSL  99
           +P   P EV +Q++ VG+C SD+    +    P     P I GHE+AG + A+G+ V   
Sbjct:  23 LPTLEPDEVLVQVQVVGLCQSDIKKIRYPLYEP-----PRIFGHETAGTIAAVGSQVKGW  77

Query: 100 QVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATP----PVDGSLARYVCHPA----- 150
           QVG RVA+   +PC++C  C    +++C   K  +T        G  A YV  P      
Sbjct:  78 QVGQRVAVMHHIPCMRCAYCMNDNFSMCDVYKNISTTAGFNASGGGFAEYVKVPGHIVEN 137

Query: 151 AWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGA 210
                +P+ +S EE +  EP +  + A ++A    G  VLV GAGPIGL+  M+ K FGA
Sbjct: 138 GGLIPIPDEISFEEASFVEPTNCCLKAVKKAQIAPGQTVLVTGAGPIGLMFVMLVKYFGA 197

Query: 211 SIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLES 270
             I  TD+   R+  A  + GA+A  + RD    D    +    +G   D+ L     E 
Sbjct: 198 KAI-ATDLLPSRIEKA-LNVGAEAAFDARD---PDLPAKIHALTNGLGVDVTLLAVPSEK 252

Query: 271 TMRLAMHVVRPGGRICLVGMGSSAMHVPLVD--ASSREIDIFGVFRYSNTYPTCIA-LLA 327
               A+   R GG+I         + +P+       REID+ G +  S       A ++ 
Sbjct: 253 AFFQALDCTRKGGKILFFAEFPDELEIPINPNILYRREIDLMGSYSSSYRLQNLSADIVF 312

Query: 328 SGRVNVKPLITHRF 341
           + R++V+ LI+ R+
Sbjct: 313 NRRIDVQALISDRY 326

ref|YP_055250.1| alcohol dehydrogenase [Propionibacterium acnes KPA171202]
gb|AAT82292.1| alcohol dehydrogenase [Propionibacterium acnes KPA171202]
(351 aa)

Score: 119 bits (298), Expect: 1.26984e-25
Length: 290, Idn/Pos/Gap = 98/146/23 (33%/50%/7%)

Query:  37 LRSVPAPAPGE--VRLQMRCVGICGSDVHYW---WHGSCGPFRLHDPMIIGHESAGVVEA  91
           +R +P PA     V ++++  G+C SD H W   W G  G      P I GHE  G+V  
Sbjct:  15 IRDIPEPAHDSDGVVVEVKACGVCRSDWHGWQGEWPGFTGG---SLPHIFGHEFVGLVSD  71

Query:  92 LGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAA 151
           +G  V+  +VGDRV +   + C  C+ CR G  N+CP +        DG  A+YV  P A
Sbjct:  72 IGNNVSRYRVGDRVIVPFTLGCGHCEYCRSGHSNVCPTVSMPGF-SYDGGFAQYVTVPDA 130

Query: 152 WC--YRLPESVSLEEGA-MCEPLSVAVHANRRAGTT-IGSLVLVLGAGPIGLLNCMVAKA 207
                +LP++V   + A M   L  A H     G    G  ++V GAG +GL   +VA +
Sbjct: 131 DANLVKLPDAVDFTDAAGMGCRLMTAYHGIVEVGQIHPGDWLVVYGAGGVGLSATLVATS 190

Query: 208 FGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAG 267
            GA++I V DI D +LA A    GA A IN+R+ D  +A   V++  DG  AD ++D  G
Sbjct: 191 AGANVIAV-DIADDKLALARK-VGAIATINSRETDPVEA---VRELTDGG-ADKSVDALG 244

Query: 268 LESTMRLAMHVVRPGGRICLVGMGSSA----MHVPLVDASSREIDIFGVF 313
           +  T+  A++ +R  G    +GM +      + + + D  ++EID  G F
Sbjct: 245 ISETLHNAVNSLRSRGTHIQIGMTAEGPVGDVALTINDLIAKEIDFRGSF 294

ref|YP_173550.1| alcohol dehydrogenase [Bacillus clausii KSM-K16]
dbj|BAD62589.1| alcohol dehydrogenase [Bacillus clausii KSM-K16]
(349 aa)

Score: 119 bits (298), Expect: 1.2912e-25
Length: 347, Idn/Pos/Gap = 102/164/34 (29%/47%/9%)

Query:  37 LRSVPAPAP--GEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGA  94
           ++ VP P    GEV ++++  G+C +D+H   HG   P +   P+I GHE  G+VE +G 
Sbjct:  24 IKEVPVPTVEYGEVLVKIKACGVCHTDLHAA-HGDW-PVKPKLPLIPGHEGVGIVEEIGE  81

Query:  95 GVTSLQVGDRVALEPGVP-----CLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHP 149
           GVTS++VGDRV    G+P     C +C+ C  GR  LCP+ +  A   VDG  A Y   P
Sbjct:  82 GVTSIKVGDRV----GIPWLYSACGECEYCLTGRETLCPD-QLNAGYSVDGGYAEYCKAP 136

Query: 150 AAWCYRLPESVSLEEGAMCEPLSVAVH-ANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAF 208
           A +  ++PE++   E +      V  + A + A    G  V + G G +G +    AKA 
Sbjct: 137 ANYIVKIPENLDFAEVSPIFCAGVTTYKALKVADAKAGDWVAIYGIGGLGHVALQYAKAM 196

Query: 209 GASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGL 268
           G +++ V DI + +L  A+   GAD  +N   +D       +++ + G QA  A+  A  
Sbjct: 197 GYNVVAV-DIMEDKLELAK-RLGADLTVNGLQVDPVQE---IKEKVGGVQA--AISVAVT 249

Query: 269 ESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFG-VFRYSNTYPTCIALLA 327
           +     A   V+ GG + +VG+ +  + +P+ D     + + G +          I   A
Sbjct: 250 KKAFEQAYGSVKRGGTLVVVGLPNDELPIPIFDTVLNGVTVKGSIVGTRKDLQESIEFAA 309

Query: 328 SGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAV--KVMLTIPE 372
            G+V            +E   L+   E      NG +  +V+LTI E
Sbjct: 310 QGKVRTN---------IETQPLDKINEVFERMENGKINGRVVLTIDE 347

dbj|BAB74034.1| sorbitol dehydrogenase [Nostoc sp. PCC 7120]
ref|NP_486375.1| sorbitol dehydrogenase [Nostoc sp. PCC 7120]
pir||AH2097 sorbitol dehydrogenase [imported] - Nostoc sp. (strain PCC 7120)
(352 aa)

Score: 119 bits (298), Expect: 1.47561e-25
Length: 314, Idn/Pos/Gap = 97/148/22 (30%/47%/7%)

Query:  40 VPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSL  99
           +P   P EV +Q++ VG+C SD+    +    P     P I GHE+AG + A+G+ V   
Sbjct:  19 LPILEPDEVLVQVQVVGLCQSDIKKIRYPLYEP-----PRIFGHETAGTIAAVGSQVQGW  73

Query: 100 QVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATP----PVDGSLARYVCHPA----- 150
           QVG RVA+   +PC++C  C    +++C   K  +T        G  A YV  P      
Sbjct:  74 QVGQRVAVMHHIPCMRCAYCMNENFSMCDVYKNISTTAGFNASGGGFAEYVKVPGHIVEN 133

Query: 151 AWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGA 210
                +P+ +S EE +  EP +  + A ++A    G  VLV GAGPIGL+  M+ K FGA
Sbjct: 134 GGLIPIPDGISFEEASFVEPTNCCLKAVKKAQIAPGQTVLVTGAGPIGLMFVMLVKYFGA 193

Query: 211 SIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLES 270
             I  TD+   R+  A  + GA+A  + RD    D    V    +G   D+ L     E 
Sbjct: 194 KAI-ATDLLPSRIEKA-LNVGAEAAFDARD---PDLPAKVHALTNGLGVDVTLLAVPSEK 248

Query: 271 TMRLAMHVVRPGGRICLVGMGSSAMHVPLVD--ASSREIDIFGVFRYSNTYPTCIA-LLA 327
               A+   R GG+I         + +P+       REID+ G +  S       A ++ 
Sbjct: 249 AFFQALECTRKGGKILFFAEFPDELEIPINPNILYRREIDLMGSYSSSYRLQNLSADIVF 308

Query: 328 SGRVNVKPLITHRF 341
           + R++V+ LI+ R+
Sbjct: 309 NRRIDVQALISDRY 322

ref|ZP_00350330.1| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Methylobacillus flagellatus KT]
(357 aa)

Score: 119 bits (298), Expect: 1.55137e-25
Length: 366, Idn/Pos/Gap = 105/167/37 (28%/45%/10%)

Query:  25 GVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHE  84
            V V P ++ +  + VP   P +  +++    ICG+DVH       G + +   + +GHE
Sbjct:   7 AVFVSPGKIALRDKPVPEIGPLDALIRITTTTICGTDVHILK----GEYPVAAGLTVGHE  62

Query:  85 SAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREG-----------RYNLCPNIKFF 133
             G++E LG+ V   +VG RV      P      C  G            + +    KF 
Sbjct:  63 PVGIIEKLGSEVHGFKVGQRVIAGAITPSGHSNACLCGIGAQDGPDSPHGFKVAGGWKFG 122

Query: 134 ATPPVDGSLARYVCHPAAWC--YRLPESVSLEEGAMC-EPLSVAVHANRRAGTTIGSLVL 190
            T  +DGS A ++  P A      +P+ +S E+  MC + +S       R    IG  V+
Sbjct: 123 NT--IDGSQAEFLRVPDAMANLSPIPDHLSDEQVLMCPDIMSTGFSGAERGNIKIGDTVV 180

Query: 191 VLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVV 250
           +   GPIGL     AK  GA+ I+  D    RL  A    GAD VIN +    HD    +
Sbjct: 181 IFALGPIGLSAVAGAKLLGATKIIGVDSIPDRLNIARA-LGADHVINFK---THDPVQEI 236

Query: 251 QQALDGAQADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIF 310
            +  DG   D+A++  G++ T   ++ V+RPGG +  +G+ SS + +PL DA    +  F
Sbjct: 237 LKLTDGRGVDVAIEALGVQQTFESSLRVLRPGGTLSSLGVYSSDLRLPL-DAFGAGLGDF 295

Query: 311 GVFRYSNTYP-------TCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGA 363
            +   S   P         +  + SGR ++  L+THRF   + S +E A++      +G 
Sbjct: 296 TIV--STLCPGGKERMRRLMEAVGSGRADLSNLVTHRF---KLSEIEEAYDLFANQRDGV 350

Query: 364 VKVMLT 369
           +KV +T
Sbjct: 351 IKVAIT 356

emb|CAB71246.1| threonine 3-dehydrogenase. [Streptomyces coelicolor A3(2)]
ref|NP_630871.1| threonine 3-dehydrogenase. [Streptomyces coelicolor A3(2)]
sp|Q9L233|TDH_STRCO L-threonine 3-dehydrogenase
(342 aa)

Score: 118 bits (296), Expect: 2.75897e-25
Length: 311, Idn/Pos/Gap = 98/154/15 (31%/49%/4%)

Query:  37 LRSVPAP--APGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGA  94
           L  VP P    G+V +++   GICG+D+H           +  P+++GHE  G V   G 
Sbjct:  15 LADVPEPTIGSGDVLIKVLRTGICGTDLHIRAWDGWAQQAIRTPLVVGHEFVGEVVDTGR  74

Query:  95 GVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAA--W 152
            VT ++ GDRV+ E  + C +C+ C  GR +LC           DG+ A YV  PA+  W
Sbjct:  75 DVTDIKAGDRVSGEGHLVCGKCRNCLAGRRHLCRATVGLGVGR-DGAFAEYVALPASNVW 133

Query: 153 CYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASI 212
            +R+P  V L+  A+ +P   AVH    +   +G  VL+ GAGPIGL+   VA+  GA  
Sbjct: 134 VHRVP--VDLDVAAIFDPFGNAVH-TALSFPLVGEDVLITGAGPIGLMAAAVARHAGARN 190

Query: 213 IVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQA-DIALDCAGLEST 271
           +V+TD+ + RL  A    GA   +N  D    D     Q+ L   +  DI L+ +G    
Sbjct: 191 VVITDVSEERLELARK-VGATLALNVSDATIADG----QRELGLREGFDIGLEMSGRPEA 245

Query: 272 MRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVF-RYSNTYPTCIALLASGR 330
           MR  +  +  GGRI ++G+ +    V      +  I + G++ R        +++L  G 
Sbjct: 246 MRDMIANMTHGGRIAMLGLPAEEFPVDWARVVTSMITVKGIYGREMFETWYAMSVLLEGG 305

Query: 331 VNVKPLITHRF 341
           +++ P+IT R+
Sbjct: 306 LDLAPVITGRY 316

emb|CAA81612.1| alcohol dehydrogenase [Geobacillus stearothermophilus]
sp|P42328|ADH3_BACST Alcohol dehydrogenase (ADH-HT)
pdb|1RJW|D Chain D, Crystal Structure Of Nad(+)-Dependent Alcohol Dehydrogenase From Bacillus Stearothermophilus Strain Lld-R
pdb|1RJW|C Chain C, Crystal Structure Of Nad(+)-Dependent Alcohol Dehydrogenase From Bacillus Stearothermophilus Strain Lld-R
pdb|1RJW|B Chain B, Crystal Structure Of Nad(+)-Dependent Alcohol Dehydrogenase From Bacillus Stearothermophilus Strain Lld-R
pdb|1RJW|A Chain A, Crystal Structure Of Nad(+)-Dependent Alcohol Dehydrogenase From Bacillus Stearothermophilus Strain Lld-R
(339 aa)

Score: 118 bits (295), Expect: 3.34264e-25
Length: 277, Idn/Pos/Gap = 93/139/20 (33%/50%/7%)

Query:  41 PAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQ 100
           P  + GEV ++++  G+C +D+H   HG   P +   P+I GHE  G+VE +G GVT L+
Sbjct:  21 PTISYGEVLVRIKACGVCHTDLHAA-HGDW-PVKPKLPLIPGHEGVGIVEEVGPGVTHLK  78

Query: 101 VGDRVALEPGVP-----CLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYR 155
           VGDRV    G+P     C  C  C  G+  LC + K  A   VDG  A Y    A +  +
Sbjct:  79 VGDRV----GIPWLYSACGHCDYCLSGQETLCEHQK-NAGYSVDGGYAEYCRAAADYVVK 133

Query: 156 LPESVSLEEGAMCEPLSVAVH-ANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIV 214
           +P+++S EE A      V  + A +  G   G  V + G G +G +    AKA G +++ 
Sbjct: 134 IPDNLSFEEAAPIFCAGVTTYKALKVTGAKPGEWVAIYGIGGLGHVAVQYAKAMGLNVVA 193

Query: 215 VTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRL 274
           V DI D +L  A+   GAD V+N     + DAA  +++ + G  A  A+  A  +   + 
Sbjct: 194 V-DIGDEKLELAK-ELGADLVVNPL---KEDAAKFMKEKVGGVHA--AVVTAVSKPAFQS 246

Query: 275 AMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFG 311
           A + +R GG   LVG+    M +P+ D     I I G
Sbjct: 247 AYNSIRRGGACVLVGLPPEEMPIPIFDTVLNGIKIIG 283

ref|ZP_00215019.1| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Burkholderia cepacia R18194]
(356 aa)

Score: 118 bits (295), Expect: 3.39889e-25
Length: 332, Idn/Pos/Gap = 106/150/23 (31%/45%/6%)

Query:  25 GVLVR-PRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRL--------  75
           GV+ R  R+L ++    P P PGE  ++M+  G+CGSD+H++ +      R         
Sbjct:   3 GVVFRGERKLEILDFEDPVPGPGEAVIEMKASGMCGSDLHFYRNKPADVIRSLGFKDLAS  62

Query:  76 -----HDPMIIGHESAGVVEALGAGVT--SLQVGDRVALEPGVPCLQCQRCREGRYNLCP 128
                  P+I GHE  G + A+GAGV   + +VGDRVA+     CL C  CR G   +C 
Sbjct:  63 RGMSEDTPVIGGHEPCGQIVAVGAGVDPRAFKVGDRVAVFHYEGCLHCDHCRTGWTQMCS 122

Query: 129 NIKFFATPPVDGSLARYVCHPAAWCYRLPESVSLEEGAMCE-PLSVAVHANRRAGTTIGS 187
           +          G  A Y+  PA     LP+ VS   GA        A  A  R   +   
Sbjct: 123 HGADIHGVIKHGGHAHYMKVPATSLVHLPDEVSFAAGAAISCGTGTAWGALLRLDISARD 182

Query: 188 LVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAA 247
            + V G GP+GL    +A A G  +I V DI   R+A A    GA  VI   D  + D  
Sbjct: 183 TLAVFGLGPVGLSAVQLAAAMGVEVIGV-DIAADRVARARAF-GATHVI---DGSKQDPI 237

Query: 248 LVVQQALDGAQADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREI 307
             +Q+   G     A+DCAG E   + A+   RP GRI LV +G +     + D   ++ 
Sbjct: 238 EEIQKLTGGLGVTCAMDCAGGEVPRQQAVRSTRPWGRIALVAVGGNLNVDGMKDVIGKQR 297

Query: 308 DIFGVFRYSN-TYPTCIALLASGRVNVKPLIT 338
            I G + +S  +   CI  +A   V+V  L T
Sbjct: 298 TIIGSYTFSEVSMKQCIHFVADHGVDVDQLFT 329

ref|ZP_00188765.1| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Rubrobacter xylanophilus DSM 9941]
(347 aa)

Score: 117 bits (294), Expect: 3.85205e-25
Length: 331, Idn/Pos/Gap = 100/158/16 (30%/47%/4%)

Query:  45 PGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGDR 104
           P +  +++    ICG+D+H    G      + +   +GHE+ G V   G GV + + GDR
Sbjct:  25 PTDAVVRIDTTTICGTDLHIL-KGDVP--EVAEGRTLGHEAVGTVVDAGPGVENFEEGDR  81

Query: 105 VALEPGVPCLQCQRCREGRYNLC-PNIKFFATPPVDGSLARYVCHPAA--WCYRLPESVS 161
           V +     C +C  CR G Y  C     +     VDG+ A +   P A    Y +PE +S
Sbjct:  82 VLVSCISACGRCAYCRRGMYGQCLQGGGWILGHLVDGTQAEFARIPFADNSLYEVPEGLS 141

Query: 162 LEEGA-MCEPLSVAVHANRRAGTT-IGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDID 219
            E+   + + L          G    G  V ++GAGPIGL + + A+ +G S I+  D+ 
Sbjct: 142 DEQVVFISDILPTGYEVGVLNGKVEPGDTVAIVGAGPIGLASMLTARLYGPSRIIAIDLA 201

Query: 220 DRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVV 279
           D RL  A    GAD  IN       DA  +V +   G  AD+ ++  G+ +T  L   +V
Sbjct: 202 DSRLEQARRF-GADTTINN---SAQDAVEMVMELTGGLGADVVMEAVGVPATFELCTGLV 257

Query: 280 RPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASGRVNVKPLITH 339
           RPGG +  +G+  +   + L    +R++ I      + + PT + L+A GR++  P  TH
Sbjct: 258 RPGGHVANIGVHGAPATLHLERLWARDVTITTGLVDTYSTPTLLRLVAEGRLDPTPFATH 317

Query: 340 RF-MGLEESSLEAAFETARTAANGAVKVMLT 369
           RF +G    + E   + ART    A+KV+L+
Sbjct: 318 RFALGEILDAYETFADAARTQ---ALKVVLS 345

ref|NP_923315.1| probable dehydrogenase [Gloeobacter violaceus PCC 7421]
dbj|BAC88310.1| glr0369 [Gloeobacter violaceus PCC 7421]
(344 aa)

Score: 117 bits (294), Expect: 3.88433e-25
Length: 307, Idn/Pos/Gap = 99/145/20 (32%/47%/6%)

Query:  41 PAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQ 100
           P P PGEV +++     CG+D+  W  G      L  P   GHE AG + ALG GV+  +
Sbjct:  20 PEPGPGEVLVRVAVAPTCGTDLKVWLRGGHARM-LVPPTPFGHEFAGEIAALGEGVSGWR  78

Query: 101 VGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYR----L 156
            G+RV      PC  C  CR  R++LC N+ F      +G+ A Y+  PAA        +
Sbjct:  79 SGERVVANNSAPCFDCFYCRRERFSLCENLLF-----NNGTFAEYLRIPAAIVRHNLLAV 133

Query: 157 PESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVT 216
           P  + LE  AM EPL+  +H    AG   G  V+V+G G IGL+   V    GA++I+  
Sbjct: 134 PPGLPLELAAMSEPLACVLHGVEEAGVRAGDTVVVMGDGAIGLMLVAVCAVRGAAVILAG 193

Query: 217 DIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALD--GAQADIALDCAGLESTMRL 274
                RLA AE   GA   +N R   +    L   +AL   G  ADI ++  G  +    
Sbjct: 194 G-QSARLAVAE-QLGAQVTLNYRQAGDPVGRL---RALTEGGRGADIVIEATGKPAAWEA 248

Query: 275 AMHVVRPGGRICLVG--MGSSAMHVPLVDASSREIDIFGVFRYSNTY-PTCIALLASGRV 331
           A+   RPG  + L G     +A+ V   +    E+ + GVF  +  +    +AL+A  R+
Sbjct: 249 AIATARPGATVLLFGGCPRGTAVSVDTENLHYNELTLKGVFHNTPRHVREALALIACRRI 308

Query: 332 NVKPLIT 338
             + L++
Sbjct: 309 AFELLVS 315

emb|CAB53146.1| putative zinc-containing dehydrogenase [Streptomyces coelicolor A3(2)]
ref|NP_624515.1| putative zinc-containing dehydrogenase [Streptomyces coelicolor A3(2)]
pir||T36961 probable zinc-containing dehydrogenase - Streptomyces coelicolor
(356 aa)

Score: 117 bits (293), Expect: 5.15846e-25
Length: 351, Idn/Pos/Gap = 108/168/26 (30%/47%/7%)

Query:  34 RVMLRSVPAPA---PGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVE  90
           R     +P P    P +  +++  V ICG+D+H    G     R     ++GHE+ G + 
Sbjct:  11 RSAWEDIPDPELKEPTDAIVRVDAVTICGTDLHIL-KGDVPEVR--PGTVLGHEAVGEIV  67

Query:  91 ALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLC-PNIKFFATPPVDGSLARYVCHP 149
            +G  V +++ GDRV +     C +C+ CREG Y  C     +     ++G+ A YV  P
Sbjct:  68 EVGTDVRTVRPGDRVLVSCITACGRCRYCREGVYGQCLGGGGWILGHLINGTQAEYVRVP 127

Query: 150 AA--WCYRLPESVSLEEGAMCEPL-----SVAVHANRRAGTTIGSLVLVLGAGPIGLLNC 202
            A    + LP +V+ E+  +   +      V V   R    + G  V+V+GAGPIGL   
Sbjct: 128 YADLSVHSLPGAVTDEDAVLLADIFPTAYEVGVLNGR---VSPGDTVVVVGAGPIGLAAV 184

Query: 203 MVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIA 262
             A+ F    IVV D+   RL  A    GA+AV + R+    D   +V     G  AD+ 
Sbjct: 185 ATARLFAPERIVVVDLATARLE-AARKLGAEAVADARE----DPEQLVADLTGGLGADVV 239

Query: 263 LDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTC 322
           ++  G+  T  +   VVRPGG +  VG+      + L D  S+ + +      + + PT 
Sbjct: 240 IEAVGVPETFEMCTRVVRPGGHVANVGVHGRPATLHLEDLWSKNVTVTTGLVDTRSTPTL 299

Query: 323 IALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAAN-GAVKVMLTIPE 372
           + + ASGR+    L+TH F  LE   +E A+E    AA+ GA+KV+L  P+
Sbjct: 300 LRMAASGRLPTGQLVTHTF-PLER--MEEAYEVFSAAADTGALKVVLGGPK 347

ref|ZP_00316104.1| COG1062: Zn-dependent alcohol dehydrogenases, class III [Microbulbifer degradans 2-40]
(368 aa)

Score: 117 bits (293), Expect: 5.28921e-25
Length: 340, Idn/Pos/Gap = 97/148/54 (28%/43%/15%)

Query:  39 SVPAPAPGEVRLQMRCVGICGSD---VHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAG  95
           +V  PA  EVR++++  G+C +D   +  W          + P I+GHE AG+V+A+G G
Sbjct:  21 TVGEPAANEVRVKIKAAGLCHTDWDSIQNW----------NKPFIVGHEGAGIVDAVGEG  70

Query:  96 VTSLQVGDRVALEPGVPCLQCQRCREGRYNLC----------------PNIKFFATPPVD 139
           VT +  GD+V L   +PC QCQ+C  G  ++C                 N   +   P++
Sbjct:  71 VTKVAPGDKVILNWAIPCGQCQQCLTGYPHICEINSPVCGKGLCGHAHANATLYNNAPLE 130

Query: 140 -----GSLARYVCHPAAWCYRLPESVSLEE------GAMCEPLSVAVHANRRAGTTIGSL 188
                G++A Y     A   +L   +S         G M    SV   AN +AG+T    
Sbjct: 131 RSFHLGTMAEYTVVKEAAVVKLETDISFSAASIVGCGVMTGWGSVVNAANVKAGST---- 186

Query: 189 VLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAAL 248
           V V+G G +GL     A+  GA+ I+  DI+D RLA A+       VI  R     D  L
Sbjct: 187 VCVIGCGGVGLNVIQAARLSGAAKIIAIDINDERLAQAKQFGATHGVIANRADSHFDEVL 246

Query: 249 V-VQQALDGAQADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREI 307
             V+Q  +   AD A +C  + +     + ++R  G    V   S        D    E 
Sbjct: 247 TQVKQINNNRAADYAFECTAVPALGSAPLKLIRSAGTAVQV---SGIEQRIDFDCELFEW 303

Query: 308 D------IFGVFRYSNTYPTCIALLASGRVNVKPLITHRF 341
           D      ++G       +P  +AL ASG++ +  LIT  +
Sbjct: 304 DKIYINPLYGQCNPERDFPRILALYASGKLKLDELITKTY 343

gb|EAA66698.1| hypothetical protein AN0599.2 [Aspergillus nidulans FGSC A4]
ref|XP_404736.1| hypothetical protein AN0599.2 [Aspergillus nidulans FGSC A4]
(391 aa)

Score: 117 bits (292), Expect: 6.35493e-25
Length: 369, Idn/Pos/Gap = 105/169/36 (28%/45%/9%)

Query:  30 PRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCG-PFRLHD------PMIIG  82
           PR++RV     P    G+V+L+    GICGSD+H +  G    P   H       P+++G
Sbjct:  25 PRDVRVEQIEEPVCGKGQVKLRNTYCGICGSDLHEYTSGPVLIPKGAHSITKATAPVVMG  84

Query:  83 HESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFF--------- 133
           HE  GVVE +G G+T L+ G +  + P +   +C  C+ G    C NI F          
Sbjct:  85 HEFGGVVEEVGEGITHLKPGQKAVVRPTIFDRKCPPCKIGYEYCCENIGFIGLSGMLFFR 144

Query: 134 ---------ATPPV----DGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRR 180
                    A  P+     G  A  +  PA   Y +P++V+ E  AM EPL+VA HA   
Sbjct: 145 IKQAVRSGQANVPMRTGYGGGFAEKIVAPAEHFYPIPDNVTPESMAMIEPLAVAWHAVNL 204

Query: 181 AGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRD 240
           +    G  VLV+G GP+GL    V K  GA+  ++ ++ + R   A+ + GA  +++ R+
Sbjct: 205 SPFKEGDNVLVVGGGPLGLCILQVLKMRGANFTIIAELTETRKKSAK-YFGATHILDPRE 263

Query: 241 LDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLV 300
           +D  D    V+   DG  AD+  D AG+E  +  A+   R  G I  V +      + + 
Sbjct: 264 VDIPDN---VRGLTDGVGADVVFDTAGVEKALDGAIGACRVHGTIVNVAVWEKKPQIKVN 320

Query: 301 DASSREIDIFGVFRY-SNTYPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTA 359
           +    E+   G   Y   ++   I  ++ G +  + +IT +     E  +E  F+T    
Sbjct: 321 EMMYHEVKYLGSALYDEKSFQDTIDAISKGLLKPESMITDKIK--LEDVVEKGFKTLLQD 378

Query: 360 ANGAVKVML 368
            N   K+++
Sbjct: 379 RNTHCKILV 387

gb|EAA66542.1| hypothetical protein AN0443.2 [Aspergillus nidulans FGSC A4]
ref|XP_404580.1| hypothetical protein AN0443.2 [Aspergillus nidulans FGSC A4]
(367 aa)

Score: 117 bits (292), Expect: 6.90792e-25
Length: 292, Idn/Pos/Gap = 80/139/9 (27%/47%/3%)

Query:  48 VRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGDRVAL 107
           ++++++  G+CG+D+H       G F    P++ GHE+ GVV A+G  V   ++GDRV  
Sbjct:  54 IQIKVKACGVCGTDLHI----HEGEFIAQFPLVPGHETVGVVAAVGPKVKGFEIGDRVVA 109

Query: 108 EPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPESVSLEEGAM 167
           +    C +C  CR G    C N +      ++G  A Y  +PA   +++ +++S  +  +
Sbjct: 110 DNSELCGECFYCRRGDELFCENFQAHGV-TMNGGFAEYCAYPAGRVFKI-QNLSDVDATL 167

Query: 168 CEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFAE 227
            EP S A H   +    +GS VL+ GAGP GL+   + +  G   +VV   +  ++  A+
Sbjct: 168 LEPASCAAHGLDKIAPKMGSRVLLFGAGPTGLILAQLLRLNGGCHVVVCAPEGLKMELAK 227

Query: 228 THAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVVRPGGRICL 287
           +    D  I     D   A     +A +    DI ++  G    +  +++ VR GG++ +
Sbjct: 228 SLGAGDEYIGLSRQDP-SAQFNKLKADNPYGFDIVVEATGNVKILEDSINYVRRGGKLVV 286

Query: 288 VGMGSSAMHV--PLVDASSREIDIFGVFRYSNTYPTCIALLASGRVNVKPLI 337
            G+ ++   V  P       EI I G F     +P  I  L SG+V V  ++
Sbjct: 287 YGVYANKDRVSWPPSKIFGDEIQIIGSFSEVYKFPAAIDYLDSGKVKVSGIV 338

gb|AAF41759.1| alcohol dehydrogenase, zinc-containing [Neisseria meningitidis MC58]
pir||C81088 alcohol dehydrogenase, zinc-containing NMB1395 [imported] - Neisseria meningitidis (strain MC58 serogroup B)
ref|NP_274409.1| alcohol dehydrogenase, zinc-containing [Neisseria meningitidis MC58]
(346 aa)

Score: 117 bits (292), Expect: 8.02736e-25
Length: 334, Idn/Pos/Gap = 97/167/25 (29%/50%/7%)

Query:  45 PGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGDR 104
           P +  +++    ICG+D+  W      P  + D  I+GHE  G+VE +G  V +++VGD+
Sbjct:  25 PTDAVVKIVKTTICGTDLGIW--KGKNP-EVADGRILGHEGIGIVEEVGEAVKNIKVGDK  81

Query: 105 VALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAA--WCYRLPESVSL 162
           V +     C  C  C+   Y+ C N  +     +DG+ A YV  P A      LP++V+ 
Sbjct:  82 VIISCVSKCCTCDNCKTQLYSHCRNGGWILGYMIDGTQAEYVRTPYADNSLVPLPDNVN- 140

Query: 163 EEGAMCEPLSVAVHANRRAGTTIGSL-----VLVLGAGPIGLLNCMVAKAFGASIIVVTD 217
           EE A+   LS A+      G   G +     V + GAGP+G+   + A+ +  + I+V D
Sbjct: 141 EEIALL--LSDALPTAHEIGVQYGDVKPGDTVFIAGAGPVGMSALLTAQLYSPAAIIVCD 198

Query: 218 IDDRRLAFAETHAGADAVIN--TRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLA 275
           +D+ RL  A+   GA   IN  + ++ +   A+V +   DG   D A++  G+ +T  + 
Sbjct: 199 MDENRLKLAK-ELGATHTINPASGEVSKQVFAIVGE---DG--VDCAIEAVGIPATWNMC 252

Query: 276 MHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASGRVNVKP 335
             +V+PGG I +VG+   ++   L     +++ I      +NT    +  ++S  V+   
Sbjct: 253 QDIVKPGGHIAVVGVHGQSVDFKLEKLWIKKLAITTGLVNANTTEMLMKAISSSSVDYTK 312

Query: 336 LITHRFMGLEESSLEAAFETARTAA-NGAVKVML 368
           ++TH F   + S LE A++  + AA N  +KV+L
Sbjct: 313 MLTHHF---KFSELEKAYDVFKHAAENQVMKVVL 343

emb|CAG97809.1| unnamed protein product [Kluyveromyces lactis NRRL Y-1140]
ref|XP_455102.1| unnamed protein product [Kluyveromyces lactis]
(385 aa)

Score: 116 bits (291), Expect: 8.16244e-25
Length: 356, Idn/Pos/Gap = 96/159/44 (26%/44%/12%)

Query:  48 VRLQMRCVGICGSDVHYWWHGSCGPF------RLHD------PMIIGHESAGVVEALGAG  95
           + +++   GICGSD+H +  G   P       ++HD      P  +GHE +G+V  +G  
Sbjct:  29 IEIEVSWCGICGSDLHEYLDG---PIFFPEDGKVHDVSGLGLPQAMGHEMSGIVSKVGPK  85

Query:  96 VTSLQVGDRVALEPGVPCL--------------QCQRCREGRYNLCPNIKFFATPPVDGS 141
           VT+++ GD V +E    CL              +C  C+ G YN C ++ F       G 
Sbjct:  86 VTNIKAGDHVVVEATGTCLDHYTWPNAAHAKDAECAACQRGFYNCCAHLGFMGLGVHSGG 145

Query: 142 LARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLN 201
            A  V        ++P ++ L+  A+ EP+SV+ HA R +    G   LVLGAGPIGL  
Sbjct: 146 FAEKVVVSEKHVVKIPNTLPLDVAALVEPISVSWHAVRISKLQKGQSALVLGAGPIGLAT 205

Query: 202 CMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEH--DAALVVQQALDGAQA 259
            +  +  GAS IVV++  + R      +  A   + T D  EH  DA  ++++   G + 
Sbjct: 206 ILALQGHGASKIVVSEPAEIR-----RNQAAKLGVETFDPSEHKEDAVNILKKLAPGGEG 260

Query: 260 -DIALDCAGLESTMRLAMHVVRPGGRICLVGM-GSSAMHVPLVDASSREIDIFGVFRYS- 316
            D A DC+G++ T    +H     G    + + G   +    +D + +E  + G   Y+ 
Sbjct: 261 FDFAYDCSGVKPTFDTGVHATTFRGMYVNIAIWGHKPIDFKPMDVTLQEKFVTGSMCYTI 320

Query: 317 NTYPTCIALLASGRVNV---KPLITHRFMGLEESSLEAAFETARTAANGAVKVMLT 369
             +   +  L +G + +   + LIT R     E      F+         +K++LT
Sbjct: 321 KDFEDVVQALGNGSIAIDKARHLITGR--QKIEDGFTKGFDELMNHKEKNIKILLT 374

ref|ZP_00267302.1| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Pseudomonas fluorescens PfO-1]
(359 aa)

Score: 116 bits (291), Expect: 1.00557e-24
Length: 366, Idn/Pos/Gap = 112/168/53 (30%/45%/14%)

Query:  34 RVMLRSVPAP--APGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEA  91
           R++L   P P   P +  +++    ICG+DVH       G + +   + +GHE  G++E 
Sbjct:  16 RIVLDDKPIPEVGPLDALIRITTTTICGTDVHILR----GEYPVAKGLTVGHEPVGIIER  71

Query:  92 LGAGVTSLQVGDRVALEPGVPCLQCQRC------------REGRYNLCPNIKFFATPPVD 139
           LG+ V     G RV      P  Q   C            R G +      KF  T  +D
Sbjct:  72 LGSQVRGFVEGQRVIAGAITPSGQSYACLCGCGSQDGPDTRHG-FRAIGGWKFGNT--ID 128

Query: 140 GSLARYVCHPAAWCY--RLPESVSLEEGAMC-EPLSVAVHANRRAGTTIGSLVLVLGAGP 196
           G  A YV  P A      +P+ +S E+  MC + +S       R   +IG  V V   GP
Sbjct: 129 GCQAEYVLVPDALANLCPIPDGLSDEQVLMCPDIMSTGFSGAERGEVSIGDSVAVFALGP 188

Query: 197 IGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQAL-- 254
           IGL     A+  GAS I+  D    R+  A    GA  V+N R+ D      VV+Q +  
Sbjct: 189 IGLCAVAGARLKGASTIIGVDAVAERMTVAR-RLGATHVVNFREGD------VVEQIMAL 241

Query: 255 -DGAQADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVF 313
            DG   D+A++  G + T   A+ V+RPGGR+  +G+ SS + +PL DA +      G+ 
Sbjct: 242 TDGRGVDVAIEALGTQGTFESALRVLRPGGRLSSLGVYSSDLRIPL-DAFAA-----GLG 295

Query: 314 RYSNTYPTC----------IALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGA 363
            YS     C          +A++ SG V++ PL+THRF   +   +EAA++      +G 
Sbjct: 296 DYSIVTTLCPGGKERMRRLMAVVQSGMVDLSPLVTHRF---KLDDIEAAYDLFAHQRDGV 352

Query: 364 VKVMLT 369
           +KV +T
Sbjct: 353 MKVAIT 358

ref|YP_148627.1| alcohol dehydrogenase [Geobacillus kaustophilus HTA426]
dbj|BAD77059.1| alcohol dehydrogenase [Geobacillus kaustophilus HTA426]
(368 aa)

Score: 116 bits (291), Expect: 1.01399e-24
Length: 325, Idn/Pos/Gap = 99/145/36 (30%/44%/11%)

Query:  42 APAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQV 101
           +P  GEV+++M+  G+C SD    WH   G   L  P+++GHE AG+VE +G GVTS++ 
Sbjct:  23 SPKRGEVKVKMKAAGLCHSD----WHVVQGQLPLPLPIVLGHEGAGIVEEVGEGVTSVKQ  78

Query: 102 GDRVALEPGVPCLQCQRCREGRYNLCPN-IKFFAT--------------PPV-----DGS 141
           GD V L     C  C  CR GR +LC    +  AT               PV      G+
Sbjct:  79 GDHVVLNWVPSCGTCSYCRTGRPDLCEEAARLMATGTLPDGTTRFSLHGKPVYQFLTAGA 138

Query: 142 LARYVCHPAAWCYRLPESVSLEEGAM--CEPLSVAVHANRRAGTTIGSLVLVLGAGPIGL 199
            + Y   P      +   V  E  A+  C  ++    A   A    GS V V+GAG +G 
Sbjct: 139 FSEYTIVPEQAAIPIRRDVPFELAALISCSVMTGVGAAIHTAQVRPGSTVAVIGAGGVGF 198

Query: 200 LNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQA 259
                A   GA  I+  DI + +LA  +T  GA   +N R   E DA   V    DG   
Sbjct: 199 NIIQGAALAGAKQIIAVDIVEEKLAMTKTF-GATHTVNAR---EDDAVSAVLDLTDGIGV 254

Query: 260 DIALDCAGLESTMRLAMHVVRPGGRICLVGMGS--SAMHVPLVDASSREIDIFGVFRYSN 317
           D A +  G   TM  A ++ R  G   +VG+ +   A+ +      S+   + G +    
Sbjct: 255 DYAFEAIGRPETMADAYNMTRKAGTTVIVGIAAPHEAVEINAFSLPSQSKALTGSWLGQG 314

Query: 318 T----YPTCIALLASGRVNVKPLIT 338
                YP  + L A+G++ ++PLI+
Sbjct: 315 NPPIDYPKLLDLYAAGKLKLEPLIS 339

gb|EAA49456.1| hypothetical protein MG01114.4 [Magnaporthe grisea 70-15]
ref|XP_368130.1| hypothetical protein MG01114.4 [Magnaporthe grisea 70-15]
(347 aa)

Score: 116 bits (290), Expect: 1.12078e-24
Length: 317, Idn/Pos/Gap = 87/140/13 (27%/44%/4%)

Query:  29 RPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGV  88
           +P+E  V+   +P     +V ++++  G+CG+D+H       G F    P+I GHE+ GV
Sbjct:  15 KPKEFAVVDVPLPELRDDDVLVKVKACGVCGTDLHI----HEGEFIAKFPLIPGHETVGV  70

Query:  89 VEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCH 148
           V A+G  V   +VGDRV+ +    C  C  CR G   LC N     T  + G  A Y  +
Sbjct:  71 VAAVGKDVKDFKVGDRVSADNAELCGHCFYCRRGESLLCENWAGHGT-TLSGGFAEYCAY 129

Query: 149 PAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAF 208
           P    ++      + E  + EP S A H   +    +GS VL+ GAGP GL+   + +  
Sbjct: 130 PQGKVFKFNNMTDV-EATLIEPASCACHGLDKIKPRLGSSVLMFGAGPTGLMLAQLLRQN 188

Query: 209 GASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQ-ALDGAQA-DIALDCA 266
           G S + +      ++  A +   AD  +   DL   D+   ++Q   D     DI ++  
Sbjct: 189 GCSQVTIAAPAGLKMDLARSLDAADTYV---DLSREDSGPQLEQLKKDNPYGFDIVIEAT 245

Query: 267 GLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDAS--SREIDIFGVFRYSNTYPTCIA 324
           G    +  +++  R GG + + G+      V          EI I G F     +P  I 
Sbjct: 246 GSVKILEDSINYCRRGGTLVVYGVYGDQDKVSWKPTKIFGDEIRIIGSFSEVFMFPQTID 305

Query: 325 LLASGRVNVKPLITHRF 341
            L +G+V  K ++   F
Sbjct: 306 YLDNGKVKTKGIVNKTF 322

ref|NP_805221.1| starvation sensing protein RspB [Salmonella enterica subsp. enterica serovar Typhi Ty2]
ref|NP_455974.1| starvation sensing protein RspB [Salmonella enterica subsp. enterica serovar Typhi str. CT18]
emb|CAD01807.1| starvation sensing protein RspB [Salmonella enterica subsp. enterica serovar Typhi]
gb|AAO69070.1| starvation sensing protein RspB [Salmonella enterica subsp. enterica serovar Typhi Ty2]
pir||AF0679 starvation sensing protein RspB [imported] - Salmonella enterica subsp. enterica serovar Typhi (strain CT18)
(287 aa)

Score: 116 bits (290), Expect: 1.24918e-24
Length: 194, Idn/Pos/Gap = 63/105/7 (32%/54%/3%)

Query:  26 VLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVH-YWWHGSCGPFRLHDPMIIGHE  84
           V+ +P  L +  R++  PA GEVR++++  GICGSD H Y  H    PF  + P +IGHE
Sbjct:   5 VIEKPNTLTIETRALLQPASGEVRIKVKLAGICGSDSHIYRGHN---PFAKY-PRVIGHE  60

Query:  85 SAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLAR 144
             GV++A+G  V   ++G+RV+++P + C  C  C  G+ N+C ++        DG  + 
Sbjct:  61 FFGVIDAVGDNVNRDRIGERVSVDPVISCGHCYPCSVGKPNVCTSLVVLGVHR-DGGFSE 119

Query: 145 YVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMV 204
           Y   PA   +R+P++++     M EP ++A +   +   T   + L+ GAGP+GL     
Sbjct: 120 YAVAPARNAHRIPDNIADHHAVMVEPFTIAANVTGQVNPTEQDVALIYGAGPMGLTTVQA 179

Query: 205 AKA-FGASIIVVTD 217
            K  +    ++V D
Sbjct: 180 LKGVYQVKTVIVVD 193

gb|AAO78722.1| sorbitol dehydrogenase [Bacteroides thetaiotaomicron VPI-5482]
ref|NP_812528.1| sorbitol dehydrogenase [Bacteroides thetaiotaomicron VPI-5482]
(338 aa)

Score: 115 bits (289), Expect: 1.41573e-24
Length: 336, Idn/Pos/Gap = 100/160/22 (29%/47%/6%)

Query:  27 LVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESA  86
           +V P E++V+    P    GEV ++++ VG CGSD++ +  G     +L  P+I GHE  
Sbjct:   6 IVNPSEMKVVELEKPTVGAGEVLVRIKYVGFCGSDLNTFL-GRNPMVKL--PVIPGHEVG  62

Query:  87 GVVEALGAGVTS-LQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARY 145
            V+E +G  V +  + G  V L P   C +C  CR GR N C + +       +G +  Y
Sbjct:  63 AVIEEIGPDVPAGFEKGMNVTLNPYTNCGKCASCRNGRVNACEHNETLGVQR-NGVMCEY 121

Query: 146 VCHPAAWCYRLPE-SVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMV 204
              P  W   +P  ++S  + A+ EP+SV  HA  RA       V+V+G G IG+   + 
Sbjct: 122 AVLP--WTKIIPAGNISSRDCALIEPMSVGFHAVSRAQVIDNEYVMVIGCGMIGIGAIVR 179

Query: 205 AKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALD 264
           A   GA++I V D+DD +L  A+   GA   +N++  + H+    +Q+   G  AD+ ++
Sbjct: 180 AALRGATVIAV-DLDDEKLVLAK-RVGASYAVNSKTENVHER---IQEITAGFGADVVIE 234

Query: 265 CAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYP---- 320
             G   T  +A+  V   GR+  +G     +         +E+DI G     N  P    
Sbjct: 235 AVGSPVTYVMAVDEVGFTGRVVCIGYAKKEVAFQTKYFVQKELDIRGS---RNALPADFR 291

Query: 321 TCIALLASGRVNVKPLITHRFMGLEESSLEAAFETA 356
             I  +  G+  V+ LI+   +   E +LEA  E A
Sbjct: 292 AVINYMKEGKCPVEELISK--IAKPEDALEAMKEWA 325

gb|AAL97696.1| putative zinc-containing alcohol dehydrogenase [Streptococcus pyogenes MGAS8232]
ref|NP_607197.1| putative zinc-containing alcohol dehydrogenase [Streptococcus pyogenes MGAS8232]
(349 aa)

Score: 115 bits (289), Expect: 1.45162e-24
Length: 337, Idn/Pos/Gap = 93/161/19 (27%/47%/5%)

Query:  41 PAPA---PGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVT  97
           P P    P +  +Q+    ICG+D+H    G   P    +  I+GHE  G+V+ +G  VT
Sbjct:  18 PKPVIIKPTDAIVQLVKTTICGTDLHIL--GGDVP-ACKEGTILGHEGIGIVKEIGDAVT  74

Query:  98 SLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAA--WCYR 155
           + ++GD+V +     C  C  C+ G  + C +  +     ++G+ A YV  P A    Y 
Sbjct:  75 NFKIGDKVIISCVTSCHTCYYCKRGLSSHCEDGGWILGHLINGTQAEYVHIPHADGSLYH 134

Query: 156 LPESVSLEEGAMCE---PLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASI 212
            P+++  E   M     P S  +     +    G  V ++GAGP+GL   + A+ F  + 
Sbjct: 135 APDTIDDEALVMLSDILPTSYEIGV-LPSHVKPGDNVCIVGAGPVGLAALLTAQFFSPAN 193

Query: 213 IVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTM 272
           I++ D+   RL  A+T  GA   I +   +E     ++    +G   DI+++C G  +T 
Sbjct: 194 IIMVDLSQNRLEAAKTF-GATHTICSGSSEE--VKTIIDDITNGRGVDISMECVGYPATF 250

Query: 273 RLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASGRVN 332
            +   ++  GG I  VG+    +   L +   + I +      +NT    + +L +G+++
Sbjct: 251 DICQKIISVGGHIANVGVHGKPVDFNLDELWIKNITLNTGLVNANTTEMLLNVLKTGKID 310

Query: 333 VKPLITHRFMGLEESSLEAAFETARTA-ANGAVKVML 368
              LITH F   + S +E A+ET + A AN A+KV++
Sbjct: 311 ATRLITHHF---KLSEVEKAYETFKHAGANNALKVII 344

ref|ZP_00166772.1| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Ralstonia eutropha JMP134]
(348 aa)

Score: 115 bits (289), Expect: 1.80329e-24
Length: 320, Idn/Pos/Gap = 96/139/17 (30%/43%/5%)

Query:  31 RELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRL--------HDPMIIG  82
           RE+ +     P P PGE  ++M+  G+CG+D+HY+ HG      +         D +I G
Sbjct:   7 REVELAHFDDPTPGPGEAVIEMKASGMCGTDLHYYRHGMAASLEMLGLKDRITSDRIIGG  66

Query:  83 HESAGVVEALGAGVTS--LQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDG 140
           HE  GVV ALG GV S   +VGDRV +     C  C  CR G   LC +          G
Sbjct:  67 HEPCGVVAALGPGVDSKAFRVGDRVMVFHYEGCRHCDHCRTGWTQLCDHGARIHGVLAHG 126

Query: 141 SLARYVCHPAAWCYRLPESVSLEEGAMCE-PLSVAVHANRRAGTTIGSLVLVLGAGPIGL 199
             A Y+  P +    LP+ +S   GA        A  A  R   +    + V G GP+GL
Sbjct: 127 GHADYMKVPVSSLVHLPQEMSFAGGAAVACGTGTAYGALLRLDISARDTLAVYGLGPVGL 186

Query: 200 LNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQA 259
               +A A G  +  V DI   R+    T A    V +  D  + D    + +   G  A
Sbjct: 187 SVAQLAAAMGVEVFGV-DISAARV----TRAKDFGVTHAIDATQSDPVAEILKLTGGKGA 241

Query: 260 DIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNT- 318
             A++CAG E     A+   R  GRI LV +G + +   + D   ++  + G F +S   
Sbjct: 242 SCAVECAGGELARAQAVRSTRVWGRIALVAVGGNLVLDAMKDLIGKQRQLLGSFTFSEVD 301

Query: 319 YPTCIALLASGRVNVKPLIT 338
              C + +A+  + V  L T
Sbjct: 302 MKACASFIATRGIEVDRLFT 321

dbj|BAA14411.1| alcohol dehydrogenase [Geobacillus stearothermophilus]
sp|P12311|ADH1_BACST Alcohol dehydrogenase (ADH-T)
(337 aa)

Score: 115 bits (289), Expect: 1.80329e-24
Length: 289, Idn/Pos/Gap = 93/142/24 (32%/49%/8%)

Query:  31 RELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVE  90
           + L+V     P  + GEV ++++  G+C +D+H   HG   P +   P+I GHE  GV+E
Sbjct:  11 KPLQVKEVEKPKISYGEVLVRIKACGVCHTDLHAA-HGDW-PVKPKLPLIPGHEGVGVIE  68

Query:  91 ALGAGVTSLQVGDRVALEPGVP-----CLQCQRCREGRYNLCPNIKFFATPPVDGSLARY 145
            +G GVT L+VGDRV    G+P     C  C  C  G+  LC   +  A   VDG  A Y
Sbjct:  69 EVGPGVTHLKVGDRV----GIPWLYSACGHCDYCLSGQETLCERQQ-NAGYSVDGGYAEY 123

Query: 146 VCHPAAWCYRLPESVSLEEGAMCEPLSVAVH-ANRRAGTTIGSLVLVLGAGPIGLLNCMV 204
               A +  ++P+++S EE A      V  + A +  G   G  V + G G +G +    
Sbjct: 124 CRAAADYVVKIPDNLSFEEAAPIFCAGVTTYKALKVTGAKPGEWVAIYGIGGLGHVAVQY 183

Query: 205 AKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADI--A 262
           AKA G +++ V D+ D +L  A+   GAD V+N +     DAA  +++ + G  A +  A
Sbjct: 184 AKAMGLNVVAV-DLGDEKLELAK-QLGADLVVNPK---HDDAAQWIKEKVGGVHATVVTA 238

Query: 263 LDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFG 311
           +  A  ES    A   +R GG   LVG+    + +P+ D     + I G
Sbjct: 239 VSKAAFES----AYKSIRRGGACVLVGLPPEEIPIPIFDTVLNGVKIIG 283

ref|YP_180875.1| alcohol dehydrogenase, zinc-containing [Dehalococcoides ethenogenes 195]
gb|AAW40552.1| alcohol dehydrogenase, zinc-containing [Dehalococcoides ethenogenes 195]
(341 aa)

Score: 115 bits (288), Expect: 1.8184e-24
Length: 336, Idn/Pos/Gap = 109/161/22 (32%/47%/6%)

Query:  26 VLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHES  85
           +L  P +L +     P+   G V L++ C  ICG+DV  +  G      L  P I+GHE 
Sbjct:   5 LLEEPAKLSLAEVDTPSCPKGGVLLEVACCAICGTDVKMFRRGH---RDLKYPRILGHEI  61

Query:  86 AGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARY 145
           A VV    +     + GDRV + PG+ C  C  C +GR NLC  +K       DG LA Y
Sbjct:  62 AAVVAC--SEHPDFKAGDRVQVYPGIACGVCPLCLQGRENLCGQVKIIGFN-YDGGLAEY 118

Query: 146 VCHPA----AWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLN 201
           +  P          +PE+VS EE ++ EPL+  +H+   +    G  VLVLGAGP+GLL 
Sbjct: 119 MALPPESLPGGLNIIPENVSDEEASLAEPLASCIHSQSVSRVGDGDRVLVLGAGPLGLLQ 178

Query: 202 CMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADI 261
            M+A+  GA  +++ ++   R+  AE  A  D VI   DL +      V +   GA  D+
Sbjct: 179 AMLARHNGAEKVLMAEVLPDRVCGAEL-ACPDGVI---DLAKTSLRQGVFEQTGGAGVDV 234

Query: 262 ALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASS---REIDIFGVFRYSNT 318
            L  +       L   V+ PGGRI              +DA++   RE+ + G +  +  
Sbjct: 235 ILIASSGVEVGELP-SVLSPGGRINFFSGLPKDRSEFSLDANTIHYRELALSGSYGSTPA 293

Query: 319 YPT-CIALLASGRVNVKPLITHRFMGLEESSLEAAF 353
             T  ++L+  G + VK LI+ R  G+  S +E AF
Sbjct: 294 DNTRALSLITDGIIPVKRLIS-RVTGI--SDIEEAF 326

emb|CAC41410.1| PUTATIVE ZINC-TYPE ALCOHOL DEHYDROGENASE PROTEIN [Sinorhizobium meliloti]
ref|NP_384129.1| PUTATIVE ZINC-TYPE ALCOHOL DEHYDROGENASE PROTEIN [Sinorhizobium meliloti 1021]
(338 aa)

Score: 115 bits (288), Expect: 1.83364e-24
Length: 318, Idn/Pos/Gap = 106/148/17 (33%/46%/5%)

Query:  26 VLVRPRELRVMLRSVP-APAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHE  84
           V   P  L ++ RS P AP PG VRL +  VGICG+D H +      PF L  P ++GHE
Sbjct:   5 VCSEPGRLALVARSGPEAPPPGSVRLAVSRVGICGTDYHIFEGKH--PF-LEYPRVMGHE  61

Query:  85 -SAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLA 143
            SA V+E  G   T L  G  V + P + C +C  CR+G+ N C  I+       DG+  
Sbjct:  62 ISARVIE--GGPGTRLAPGTLVVVNPYLSCGECIACRKGKPNCCTAIRVLGVH-TDGAFC 118

Query: 144 RYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCM 203
             +  P    Y   E +S E  A  E L++  HA RR+    G   LV+GAGPIGL   +
Sbjct: 119 EEIVMPEQNLYP-AEGLSPEAAAAVEFLAIGAHAVRRSAAGRGVRSLVIGAGPIGLGTAV 177

Query: 204 VAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIAL 263
            ++  G  + ++ D  + RLAFA    G    I   D    DAAL   QA  G   D+  
Sbjct: 178 FSRIAGHDVRLL-DTSEERLAFATEKLGFSPGILAGD----DAALA--QATGGDGFDVVF 230

Query: 264 DCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNT-YPTC 322
           D  G   +M  A   V  GG +  V +    +     +   RE+ +      +   +   
Sbjct: 231 DATGNAQSMERAFGHVAHGGTLVFVSVVKEEIRFSDPEFHKREMTLVASRNATREDFDHV 290

Query: 323 IALLASGRVNVKPLITHR 340
           I  LA+G V ++ L+THR
Sbjct: 291 IQSLAAGLVPIEALVTHR 308

ref|YP_146791.1| alcohol dehydrogenase [Geobacillus kaustophilus HTA426]
dbj|BAD75223.1| alcohol dehydrogenase [Geobacillus kaustophilus HTA426]
(378 aa)

Score: 115 bits (288), Expect: 2.18479e-24
Length: 377, Idn/Pos/Gap = 108/167/55 (28%/44%/14%)

Query:  35 VMLRSVPAPA---PGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEA  91
           V ++ +P P      ++ +++    ICGSD+H   HG      + +  IIGHE  G+VE 
Sbjct:  12 VAVKQMPDPKILKDDDIIVKITSTAICGSDLHLV-HGMIP--NMPEDFIIGHEPMGIVEE  68

Query:  92 LGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLC----PN---------IKFFATPPV 138
           +G  VT ++ GDRV +   + C QC  C+ G  + C    PN          + F   P 
Sbjct:  69 VGPAVTKVKKGDRVIVPFTIACGQCWYCQHGLESQCDASNPNGESGGYFGYSETFGGYP- 127

Query: 139 DGSLARYVCHPAA--WCYRLPESVSLEEGA---MCEPLSVAVHANRRAGTTIGSLVLVLG 193
            G  A Y+  P A    + +PE+  LE+     + + +  A      AG   G  V+VLG
Sbjct: 128 -GGQAEYLRVPFANFTPFVVPENCELEDEKLLFLSDIIPTAFWGVDEAGVKDGDTVVVLG 186

Query: 194 AGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQA 253
            GP+GLL    A   GA  ++  D  D R+     HA     + T +  E++      + 
Sbjct: 187 CGPVGLLTQKFAWMKGAKRVIAVDYIDYRI----EHAKKTNKVETLNFTEYENVGEYIKE 242

Query: 254 LDGAQADIALDCAGLESTMR--------------------LAMHVVRPGGRICLVGM-GS 292
           + G  AD+ +DC GL+  M                     +A   VR GG I LVG+ G+
Sbjct: 243 MTGGGADVVIDCVGLDGKMTPLELIGSALKLQGGAMGAIVIASQAVRKGGTIQLVGVYGA 302

Query: 293 SAMHVPLVDASSREIDI-FGVFRYSNTYPTCIALLASGRVNVKPLITHRFMGLEESSLEA 351
                PL D  SR I +  G     +  PT    +  G+ +   +ITHR + L+E+  + 
Sbjct: 303 RYNQFPLGDLFSRNITLKMGQAPVIHYIPTLYEWIVEGKFDPTDIITHR-LPLDEA--QY 359

Query: 352 AFETARTAANGAVKVML 368
           A+E      +G +KV+L
Sbjct: 360 AYEIFDEKKDGCIKVVL 376

ref|ZP_00187339.2| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Rubrobacter xylanophilus DSM 9941]
(364 aa)

Score: 115 bits (288), Expect: 2.29695e-24
Length: 322, Idn/Pos/Gap = 104/153/45 (32%/47%/13%)

Query:  27 LVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMI----IG  82
           L  P  + V    VP P PG V  ++R   +CGS+VH         +  H P+I    +G
Sbjct:   8 LAGPERVEVRSFDVPEPEPGAVVARVRRANVCGSEVHI--------YHFHHPLIRECVLG  59

Query:  83 HESAGVVEALGAGVTS------LQVGDRVALEPGVPCLQCQRCREGRYNLCPNI-KFFAT 135
           HE  G + ALG GVT+      ++ GDRV     + C +C  C  G +NLC     F++ 
Sbjct:  60 HEFVGEIVALGEGVTTDYAGQPVREGDRVTAPYYLTCRRCPACLRGDFNLCQRAYAFWSR 119

Query: 136 PP-----VDGSLA-RYVCHPAAWCYRLPESVSLE--EGAMCEPLSVAVHANRRAGTTIGS 187
           PP       G+ A  Y  HP  + YR+PE +  E   GA C  LS  +    RAG + G 
Sbjct: 120 PPEVEPHFHGAFATHYYIHPDQYFYRVPEGLPDEVVAGANCG-LSQVLFGLHRAGLSAGD 178

Query: 188 LVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEH--- 244
            ++V GAG +GL    V +  GA ++ V  I + RL  A    GA+ V+   D+ EH   
Sbjct: 179 TLVVQGAGGLGLYAAAVGRHMGARVVAVEGIPE-RLELARRF-GAEEVV---DMAEHPTP 233

Query: 245 -DAALVVQQALDGAQADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAM----HVPL 299
            + A  V++   G  AD+ L+  G+ +    A+ + RPGG  C+V +G+  +     VPL
Sbjct: 234 GERAGRVRELTGGYGADVVLEVTGVPAAFVEALELARPGG--CVVEIGNVNVGREHEVPL 291

Query: 300 VDA--SSREIDIFGVFRYSNTY 319
                + + + I G  RY   Y
Sbjct: 292 APGLITRKMLRIQGFVRYQPWY 313

gb|AAR91477.1| thermostable alcohol dehydrogenase [Geobacillus sp. M10EXG]
(340 aa)

Score: 115 bits (288), Expect: 2.3162e-24
Length: 277, Idn/Pos/Gap = 91/140/20 (32%/50%/7%)

Query:  41 PAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQ 100
           P+ + GEV ++++  G+C +D+H   HG   P +   P+I GHE  G+VE +G GVT L+
Sbjct:  21 PSISYGEVLVRIKACGVCHTDLHAA-HGDW-PVKPKLPLIPGHEGVGIVEEVGPGVTHLK  78

Query: 101 VGDRVALEPGVP-----CLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYR 155
           VGDRV    G+P     C  C+ C  G+  LC + +  A   VDG  A Y      +  +
Sbjct:  79 VGDRV----GIPWLYSACGHCEYCLSGQEALCEHQQ-NAGYSVDGGYAEYCRAAPDYVVK 133

Query: 156 LPESVSLEEGAMCEPLSVAVH-ANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIV 214
           +P+++S EE A      V  + A +  GT  G  V + G G +G +    AKA G  ++ 
Sbjct: 134 IPDNLSFEEAAPIFCAGVTTYKALKVTGTKPGEWVAIYGIGGLGHVAVQYAKAMGLHVVA 193

Query: 215 VTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRL 274
           V DI D +L  A+   GAD V+N     + +AA  +++ + G  A  A+  A  +   + 
Sbjct: 194 V-DIGDEKLELAK-ELGADLVVNPA---KENAAQFMKEKVGGVHA--AVVTAVSKPAFQS 246

Query: 275 AMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFG 311
           A + +R GG   LVG+    M +P+ D     I I G
Sbjct: 247 AYNSIRRGGTCVLVGLPPEEMPIPIFDTVLNGIKIIG 283

gb|AAK33988.1| putative zinc-containing alcohol dehydrogenase [Streptococcus pyogenes M1 GAS]
ref|NP_269267.1| putative zinc-containing alcohol dehydrogenase [Streptococcus pyogenes M1 GAS]
(349 aa)

Score: 114 bits (286), Expect: 3.15392e-24
Length: 337, Idn/Pos/Gap = 93/161/19 (27%/47%/5%)

Query:  41 PAPA---PGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVT  97
           P P    P +  +Q+    ICG+D+H    G   P    +  I+GHE  G+V+ +G  VT
Sbjct:  18 PKPVIIKPTDAIVQLVKTTICGTDLHIL--GGDVP-ACKEGTILGHEGIGIVKEVGDAVT  74

Query:  98 SLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAA--WCYR 155
           + ++GD+V +     C  C  C+ G  + C +  +     ++G+ A YV  P A    Y 
Sbjct:  75 NFKIGDKVIISCVTSCHTCYYCKRGLSSHCQDGGWILGHLINGTQAEYVHIPHADGSLYH 134

Query: 156 LPESVSLEEGAMCE---PLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASI 212
            P+++  E   M     P S  +     +    G  V ++GAGP+GL   +  + F  + 
Sbjct: 135 APDTIDDEALVMLSDILPTSYEIGV-LPSHVKPGDNVCIVGAGPVGLAALLTVQFFSPAN 193

Query: 213 IVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTM 272
           I++ D+   RL  A+T  GA   I +   +E  A  ++    +G   DI+++C G  +T 
Sbjct: 194 IIMVDLSQNRLEAAKTF-GATHTICSGSSEEVKA--IIDDITNGRGVDISMECVGYPATF 250

Query: 273 RLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASGRVN 332
            +   ++  GG I  VG+    +   L +   + I +      +NT    + +L +G+++
Sbjct: 251 DICQKIISVGGHIANVGVHGKPVDFNLDELWIKNITLNTGLVNANTTEMLLNVLKTGKID 310

Query: 333 VKPLITHRFMGLEESSLEAAFETARTA-ANGAVKVML 368
              LITH F   + S +E A+ET + A AN A+KV++
Sbjct: 311 ATRLITHHF---KLSEVEKAYETFKHAGANNALKVII 344

gb|AAQ04630.1| sorbitol dehydrogenase [Paracoccidioides brasiliensis]
(124 aa)

Score: 114 bits (286), Expect: 3.15392e-24
Length: 115, Idn/Pos/Gap = 53/76/1 (46%/66%/0%)

Query:  19 EKANPCGVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDP  78
           EK     VL  PR+LR+  R  PAP  GE+++ +R  G+CGSD+HY+ HG  G F +  P
Sbjct:   7 EKLTHALVLHAPRDLRLESRLTPAPKHGELQIAIRATGLCGSDLHYYNHGRNGDFIVQSP  66

Query:  79 MIIGHESAGVVEALGAGVT-SLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKF 132
           + +GHES+G++ A+G  V  +  +GDRVALE G+PC  C  C +GRYN+C  ++F
Sbjct:  67 LCLGHESSGIITAIGPDVADTFHIGDRVALEVGLPCHSCPLCLQGRYNICRKLRF 121

emb|CAB12443.1| ydjL [Bacillus subtilis subsp. subtilis str. 168]
ref|NP_388505.1| hypothetical protein BSU06240 [Bacillus subtilis subsp. subtilis str. 168]
pir||H69789 probable alcohol dehydrogenase (EC 1.1.1.-) ydjL [similarity] - Bacillus subtilis
dbj|BAA22767.1| dehydrogenase [Bacillus subtilis]
(346 aa)

Score: 114 bits (285), Expect: 4.08492e-24
Length: 320, Idn/Pos/Gap = 90/149/17 (28%/46%/5%)

Query:  31 RELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSC-----GPFRLHD---PMIIG  82
           +++R+     P   PG+V+++++  GICGSD+H +  G        P  L +   P+ +G
Sbjct:  10 KDIRIEHIEEPKTEPGKVKIKVKWCGICGSDLHEYLGGPIFIPVDKPHPLTNETAPVTMG  69

Query:  83 HESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSL 142
           HE +G V  +G GV + +VGDRV +EP    +      +G YNL   + F       G  
Sbjct:  70 HEFSGEVVEVGEGVENYKVGDRVVVEP----IFATHGHQGAYNLDEQMGFLGLAGGGGGF 125

Query: 143 ARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNC 202
           + YV       ++LP+ +S E+GA+ EP +VA++A R +    G    V G GPIGLL  
Sbjct: 126 SEYVSVDEELLFKLPDELSYEQGALVEPSAVALYAVRSSKLKAGDKAAVFGCGPIGLLVI 185

Query: 203 MVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIA 262
              KA GA+ I   ++   R   AE   GA  V    D  + D  +       G   D+A
Sbjct: 186 EALKAAGATDIYAVELSPERQQKAE-ELGAIIV----DPSKTDDVVAEIAERTGGGVDVA 240

Query: 263 LDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTC 322
            +  G+   +R A+      G   +V +      +   D   +E  + G+  Y + +P  
Sbjct: 241 FEVTGVPVVLRQAIQSTTIAGETVIVSIWEKGAEIHPNDIVIKERTVKGIIGYRDIFPAV 300

Query: 323 IALLASGRVNVKPLITHRFM 342
           ++L+  G  +   L+T + +
Sbjct: 301 LSLMKEGYFSADKLVTKKIV 320

ref|NP_355742.1| hypothetical protein AGR_C_5103 [Agrobacterium tumefaciens str. C58]
ref|NP_533479.1| zinc-binding dehydrogenase [Agrobacterium tumefaciens str. C58]
gb|AAL43795.1| zinc-binding dehydrogenase [Agrobacterium tumefaciens str. C58]
gb|AAK88527.1| AGR_C_5103p [Agrobacterium tumefaciens str. C58]
pir||F97696 hypothetical zinc-type alcohol dehydrogenase-like protein in tsr-mdoB intergenic region [imported] - Agrobacterium tumefaciens (strain C58, Cereon)
pir||AE2922 zinc-binding dehydrogenase Atu2814 [imported] - Agrobacterium tumefaciens (strain C58, Dupont)
(336 aa)

Score: 114 bits (285), Expect: 4.08492e-24
Length: 303, Idn/Pos/Gap = 95/141/17 (31%/46%/5%)

Query:  41 PAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQ 100
           P    GEV +++R +G+CG+D+H +      P+ L  P I+GHE +G VE   AG + L 
Sbjct:  20 PVRGEGEVLVRIRRIGVCGTDLHIFTGNQ--PY-LSYPRIMGHELSGTVEEAPAG-SHLS  75

Query: 101 VGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPESV 160
            GD V + P + C +C  C +G+ N C NI        DG +  Y+  P  +  +  E +
Sbjct:  76 AGDVVTIIPYMSCGKCNACLKGKSNCCRNIGVLGVHR-DGGMVEYLSVPQQFVLK-AEGL 133

Query: 161 SLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDD 220
           SL++ AM E L++  HA RR     G  VL++GAGPIG+   + A   G     VT ID 
Sbjct: 134 SLDQAAMTEFLAIGAHAVRRGAVEKGQKVLIVGAGPIGMAVAVFAVLDGTE---VTMIDG 190

Query: 221 R--RLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHV 278
           R  RL F + H G    +   D D+   + +      G   D   D  G    M      
Sbjct: 191 RTDRLDFCKDHLGVAHTVALGDGDKDRLSDIT----GGNFFDAVFDATGNPKAMERGFSF 246

Query: 279 VRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYS-NTYPTCIALLASGRVNVKPLI 337
           V  GG   LV + +S +     +   RE  + G    + + +   +  L  G+V  + LI
Sbjct: 247 VGHGGSYVLVSIVASDISFNDPEFHKRETTLLGSRNATADDFERVLRALREGKVP-EALI 305

Query: 338 THR 340
           THR
Sbjct: 306 THR 308

gb|AAO79617.1| putative zinc-type alcohol dehydrogenase [Bacteroides thetaiotaomicron VPI-5482]
ref|NP_813423.1| putative zinc-type alcohol dehydrogenase [Bacteroides thetaiotaomicron VPI-5482]
(350 aa)

Score: 114 bits (285), Expect: 4.94911e-24
Length: 340, Idn/Pos/Gap = 100/157/19 (29%/46%/5%)

Query:  37 LRSVPAPAPGEVR---LQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALG  93
           LR  P P   + R   +++    IC SD+H   HGS    R    + +GHE  GVVE +G
Sbjct:  14 LREKPEPKITDARDAIVRVTLGSICTSDLHIK-HGSVP--RAVPGITVGHEMVGVVEEVG  70

Query:  94 AGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLC--PNIKFFATPPVDGSLARYVCHPAA 151
           A VTS++ GDRV +     C +C  C  G  N C  PN  +     +DG  A YV  P A
Sbjct:  71 AEVTSVRPGDRVTVNVETFCGECFFCHHGYVNNCTDPNGGWALGCRIDGGQAEYVRVPYA 130

Query: 152 --WCYRLPESVSLEEGAMC-EPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAF 208
                R+P++VS E+     + L+    A R +  T    +L++GAGP G+   + +   
Sbjct: 131 DQGLNRIPDTVSDEQALFVGDVLATGFWATRISEITEKDTILLIGAGPTGICTLLCSMLK 190

Query: 209 GASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGL 268
               I+V +    R+ F   H   D +I T    E+    V+Q + D + AD+ L+ AG 
Sbjct: 191 NPKRIIVCEKSPERIQFVREHY-PDVLITT---PENCKEFVLQNS-DHSGADVVLEVAGT 245

Query: 269 ESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLAS 328
           E + R+A    RP   + +V +    +  PL +   + +               ++L+  
Sbjct: 246 EDSFRMAWDCARPNAIVTIVALYDKPLLFPLPEMYGKNLTFKTGGVDGCDCAEILSLIEE 305

Query: 329 GRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVML 368
           G+++  PLITHR   L E  +E A+       +G +KV +
Sbjct: 306 GKIDTTPLITHR-CSLNE--IEEAYRIFENKLDGVIKVAI 342

ref|NP_756683.1| Putative dehydrogenase [Escherichia coli CFT073]
gb|AAN83257.1| Putative dehydrogenase [Escherichia coli CFT073]
(336 aa)

Score: 114 bits (284), Expect: 5.51613e-24
Length: 331, Idn/Pos/Gap = 105/155/35 (31%/46%/10%)

Query:  45 PGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGDR 104
           P EVR+     GICGSD+H    G   PF    P++ GHE A  V  +G+ V ++Q GD 
Sbjct:  29 PHEVRIAPVFYGICGSDLHVLKGGH--PFA-KPPVVPGHEIAARVTEVGSDVKNVQPGDH  85

Query: 105 VALEPGVPCLQCQRCREGRYNLC--PNIKFFATPPVDGSLARYVCHPAAWCYRLPESVSL 162
           V ++P + C++C+ C+ GR+NLC  P +  F  P    + ++++  PA  C+  P S+ L
Sbjct:  86 VVVDPIMACMECRACKAGRFNLCEPPQVAGFRAPGF--ARSQHIV-PARNCHVAPASLPL 142

Query: 163 EEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRR 222
           +  A  EP + A H   R        VLV+GAG IGL      +  GA  I V + D  +
Sbjct: 143 KVLAFAEPAACARHCVNRMPKASLESVLVIGAGTIGLSIVQALRIMGAGKITVIEPDAAK 202

Query: 223 LAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADI----ALDCAGLESTMRLAMHV 278
            A A    GA  V    +L                 AD+    A+D    ++T+  A   
Sbjct: 203 RALA-LKLGAAEVWAPGEL----------------AADVRFTGAIDVVAAQATLNDACTR 245

Query: 279 VRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRY-SNTYPTCIALLASGRVNVKPLI 337
           V  GG +  +G+ S    +PL      E D+     Y    +   I  LA GR +   L+
Sbjct: 246 VYAGGTVVCMGVPSGPREIPLPMMQRFERDLLNSGMYIPEDFDAVIEWLADGRFDTSELV 305

Query: 338 THRFMGLEESSLEAAFETARTAANGAVKVML 368
           T  F  +E+++  AAFE  R   N ++KVML
Sbjct: 306 TDLF-AIEDAA--AAFE--RAQQNDSIKVML 331

ref|NP_802234.1| putative zinc-containing alcohol dehydrogenase [Streptococcus pyogenes SSI-1]
ref|NP_664576.1| putative zinc-containing alcohol dehydrogenase [Streptococcus pyogenes MGAS315]
gb|AAM79379.1| putative zinc-containing alcohol dehydrogenase [Streptococcus pyogenes MGAS315]
dbj|BAC64067.1| putative zinc-containing alcohol dehydrogenase [Streptococcus pyogenes SSI-1]
(349 aa)

Score: 114 bits (284), Expect: 5.8479e-24
Length: 337, Idn/Pos/Gap = 92/160/19 (27%/47%/5%)

Query:  41 PAPA---PGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVT  97
           P P    P +  +Q+    ICG+D+H    G   P    +  I+GHE  G+V+ +G  VT
Sbjct:  18 PKPVIIKPTDAIVQLVKTTICGTDLHIL--GGDVP-ACKEGTILGHEGIGIVKEVGDAVT  74

Query:  98 SLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAA--WCYR 155
           + ++GD+V +     C  C  C+ G  + C +  +     ++G+ A YV  P A    Y 
Sbjct:  75 NFKIGDKVIISCVTSCHTCYYCKRGLSSHCEDGGWILGHLINGTQAEYVHIPHADGSLYH 134

Query: 156 LPESVSLEEGAMCE---PLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASI 212
            P+++  E   M     P S  +     +    G  V ++GAGP+GL   +  + F  + 
Sbjct: 135 APDTIDDEALVMLSDILPTSYEIGV-LPSHVKPGDNVCIVGAGPVGLAALLTVQFFSPAN 193

Query: 213 IVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTM 272
           I++ D+   RL  A+T  GA   I +   +E     ++    +G   DI+++C G  +T 
Sbjct: 194 IIMVDLSQNRLEAAKTF-GATHTICSGSSEE--VKTIIDDITNGRGVDISMECVGYPATF 250

Query: 273 RLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASGRVN 332
            +   ++  GG I  VG+    +   L +   + I +      +NT    + +L +G+++
Sbjct: 251 DICQKIISVGGHIANVGVHGKPVDFNLDELWIKNITLNTGLVNANTTEMLLNVLKTGKID 310

Query: 333 VKPLITHRFMGLEESSLEAAFETARTA-ANGAVKVML 368
              LITH F   + S +E A+ET + A AN A+KV++
Sbjct: 311 ATRLITHHF---KLSEVEKAYETFKHAGANNALKVII 344

ref|ZP_00284346.1| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Burkholderia fungorum LB400]
(346 aa)

Score: 113 bits (283), Expect: 8.58396e-24
Length: 321, Idn/Pos/Gap = 97/150/19 (30%/46%/5%)

Query:  57 ICGSDVHYWWHG--SCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCL 114
           ICG+D+H       +C P R     I+GHE  G+V+ +GA V+SL+ GD V +     C 
Sbjct:  37 ICGTDLHILKGDVPTCQPGR-----ILGHEGVGIVQQVGAAVSSLKEGDHVLISCISACG  91

Query: 115 QCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVA 174
           +C  CR G Y+ C    +     +DG+ A YV  P A     P     +E A+   LS  
Sbjct:  92 KCDYCRRGMYSHCTTGGWILGNRIDGTQAEYVRIPHAETSLYPIPAGADEEALVM-LSDI 150

Query: 175 VHANRRAG-----TTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFAETH 229
           +      G        GS V ++GAGPIGL + + A+ +  + I++ D D+RRL  A + 
Sbjct: 151 LPTGFECGVLNGKVQPGSAVAIVGAGPIGLASLLTAQFYSPAQIIMIDRDERRLEVA-SR 209

Query: 230 AGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVVRPGGRICLVG 289
            GA A I++R     +  + V +       D A++  G+  T  L   +V PGG I  +G
Sbjct: 210 FGATACIDSR---VAEPVVEVMKLTGHVGVDCAIEAVGVPDTFELCQALVAPGGVIANIG 266

Query: 290 MGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASGRVNVKPLITHRFMGLEESSL 349
           +      + L     R I I      + + P  +  + SGR++   LITH F    +  L
Sbjct: 267 VHGVKADLHLESLWDRNISITTRLVDTVSTPMLLKTVQSGRIDPARLITHHFQ--LDDVL 324

Query: 350 EAAFETARTAANGAVKVMLTI 370
            A     R A + A+KV++ +
Sbjct: 325 NAYDTFGRAADSHALKVIIEM 345

gb|AAQ59723.1| probable zinc-containing alcohol dehydrogenase [Chromobacterium violaceum ATCC 12472]
ref|NP_901721.1| probable zinc-containing alcohol dehydrogenase [Chromobacterium violaceum ATCC 12472]
(358 aa)

Score: 113 bits (283), Expect: 8.65589e-24
Length: 337, Idn/Pos/Gap = 97/155/34 (28%/45%/10%)

Query:  26 VLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHES  85
           V V P  + +  + +PA  PG+  +++    ICG+DVH       G + +   + IGHE 
Sbjct:   8 VFVGPGRIELREKPIPAVGPGDALVKITTTTICGTDVHILK----GEYPVASGLTIGHEP  63

Query:  86 AGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGR-----------YNLCPNIKFFA 134
            GV+E LGA V   + G RV      P      C++G            Y      +F  
Sbjct:  64 VGVIEKLGADVKGYREGQRVIAGAICPSFTSYGCQDGHPAQDGGCECHGYKPMGGWRFGN 123

Query: 135 TPPVDGSLARYVCHPAAWC--YRLPESVSLEEGAMC-EPLSVAVHANRRAGTTIGSLVLV 191
           T  +DG+ A YV  P A      +P+ +S E+  MC + +S        A   IG +V+V
Sbjct: 124 T--IDGTQAEYVLVPDAQANLAPIPDGLSDEQVLMCPDIMSTGFAGAEAANIRIGDVVVV 181

Query: 192 LGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQ 251
              GPIGL     A+  GAS I+  D  D RL  +    GAD  +N + +D       + 
Sbjct: 182 FAQGPIGLCAVAGARLRGASCIIAVDGLDERLGISR-RLGADVTLNFKQVD---VIAEIM 237

Query: 252 QALDGAQADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFG 311
           +   G   D +++  G + T   A+ V++PGG +  +G+ SS + +PL DA +  +    
Sbjct: 238 KLTGGRGVDASIEALGTQGTFESALRVLKPGGTLSSLGVYSSDLRIPL-DAFNAGLGDKR 296

Query: 312 VFRYSNTYP-------TCIALLASGRVNVKPLITHRF 341
           +   S+  P         + +L S R+++ PL+THR+
Sbjct: 297 IV--SSLCPGGKERMRRLMNVLESDRLDLSPLVTHRY 331

emb|CAF60530.1| GntP-like protein [Streptomyces kanamyceticus]
dbj|BAD20754.1| dehydrogenase [Streptomyces kanamyceticus]
(343 aa)

Score: 113 bits (283), Expect: 8.72841e-24
Length: 357, Idn/Pos/Gap = 110/164/32 (30%/45%/8%)

Query:  26 VLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYW---WHGSCGPFRLHDPMIIG  82
           V   P +     R VP P PGE  + +    ICGSD+  +   WHG         P++ G
Sbjct:   5 VFHSPEKATFEQRDVPTPRPGEALVHIAYNSICGSDLSLYRGVWHG------FGYPVVPG  58

Query:  83 HESAG-VVEALGA-GVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDG 140
           HE +G VVE  GA G     VG  V  +    C  C  C  G   LC N++       DG
Sbjct:  59 HEWSGTVVEINGANGHDQSLVGKNVVGDLTCACGNCAACGRGTPVLCENLQELGFTK-DG 117

Query: 141 SLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLL 200
           + A Y+  P      LP+++SL      EPL+VA++A   AG   G  V V+GAG IGL+
Sbjct: 118 ACAEYMTIPVDNLRPLPDALSLRSACQVEPLAVALNAVSIAGVAPGDRVAVMGAGGIGLM 177

Query: 201 NCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQAD 260
              VA+  G  + VV++    R A A    GA  + +        A LV ++       D
Sbjct: 178 LMQVARHLGGEVTVVSEPVAERRAVA-GQLGATELCSAE--PGQLAELVARRP--ELTPD 232

Query: 261 IALDCAGLESTMRLAMHVVRPGGRICLVGM------GSSAMHVPLVDASSREIDIFGVFR 314
           + L+ +G  + ++ A+ VVRPGGRI L+G         S  H+ +     + + + G   
Sbjct: 233 VVLEASGYPAALQEAIEVVRPGGRIGLIGYRVEETGPMSPQHIAV-----KALTLRGSLG 287

Query: 315 YSNTYPTCIALLASG-RVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLTI 370
               +   + LLA G  + V+PL++H F GL + +   A + A +  NG V+    +
Sbjct: 288 PGGRFDDAVELLAKGDDIAVEPLLSHEF-GLADYA--TALDLALSRTNGNVRSFFNL 341

ref|YP_216294.1| Hypothetical zinc-type alcohol dehydrogenase-like [Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67]
gb|AAX65213.1| Hypothetical zinc-type alcohol dehydrogenase-like [Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67]
(358 aa)

Score: 113 bits (283), Expect: 8.87529e-24
Length: 351, Idn/Pos/Gap = 104/160/37 (29%/45%/10%)

Query:  40 VPAP--APGEVRLQMRCVGICGSDV-HYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGV  96
           VP P   P +V ++++   ICG+D+ HY        F      + GHE AG +  +G  V
Sbjct:  19 VPEPVCGPEDVIIEIKAAAICGADMKHYNVDSGSDEFN----SVRGHEFAGRIARVGEKV  74

Query:  97 TSLQVGDRVALE-PGVPCLQCQRCREGRYNLCPNIKF---FATPPVDGSLARYVCHP--- 149
              +VG RV  +  G  C  C  C +G + LC   K           G  ++Y   P   
Sbjct:  75 KDWKVGQRVVSDNSGHVCGVCPACEQGDF-LCCTEKVNLGLDNNTWGGGFSKYCLVPGEI 133

Query: 150 ------AAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTI-GSLVLVLGAGPIGLLNC 202
                 A W   +PE V  EE A+ +P+  A  +  +    + G  V+V+G GP+GL + 
Sbjct: 134 LKIHRHALW--EIPEGVDYEEAAVLDPICNAYKSIAQQSKFLPGQDVVVIGTGPLGLFSV 191

Query: 203 MVAKAFGASIIVVTDIDDR---RLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQA 259
            +A+  GA  IVV  +D+    R   A+   GA A +N       D     Q+       
Sbjct: 192 QMARIMGAVNIVVVGLDEDVPVRFPVAK-ELGATAFVNG---STEDVVARCQEICGKDNL 247

Query: 260 DIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRY-SNT 318
            + ++C+G    ++ A+ ++RP G +  VGMG   +   + D +S    I G   Y S +
Sbjct: 248 GLVIECSGANIALKQAIDMLRPNGEVVRVGMGFKPLDFSINDITSWNKSIIGHMAYDSTS 307

Query: 319 YPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLT 369
           +   I LLASG + VKP+ITHR +GL  S     F+        A+KV++T
Sbjct: 308 WRNAIRLLASGAIKVKPMITHR-IGL--SQWREGFDA--MVDKTAIKVIMT 353

gb|AAT92941.1| YAL060W [Saccharomyces cerevisiae]
(382 aa)

Score: 112 bits (281), Expect: 1.42801e-23
Length: 257, Idn/Pos/Gap = 81/122/33 (31%/47%/12%)

Query:  47 EVRLQMRCVGICGSDVHYWWHGSCGPFRLHD-----------PMIIGHESAGVVEALGAG  95
           EV + +   GICGSD+H +  G    F   D           P+ +GHE +G+V  +G  
Sbjct:  28 EVIIDVSWCGICGSDLHEYLDGPI--FMPKDGECHKLSNAALPLAMGHEMSGIVSKVGPK  85

Query:  96 VTSLQVGDRVALEPGVPCLQ--------------CQRCREGRYNLCPNIKFFATPPVDGS 141
           VT ++VGD V ++    C                C  C+ G  NLC +  F     + G 
Sbjct:  86 VTKVKVGDHVVVDAASSCADLHCWPHSKFYNSKPCDACQRGSENLCTHAGFVGLGVISGG 145

Query: 142 LARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLN 201
            A  V         +P+ + L+  A+ EPLSV  HA + +G   GS  LVLGAGPIGL  
Sbjct: 146 FAEQVVVSQHHIIPVPKEIPLDVAALVEPLSVTWHAVKISGFKKGSSALVLGAGPIGLCT 205

Query: 202 CMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALV--VQQALDGAQA 259
            +V K  GAS IVV++I +RR+  A+   G + V N          ++  + ++ DG   
Sbjct: 206 ILVLKGMGASKIVVSEIAERRIEMAKK-LGVE-VFNPSKHGHKSIEILRGLTKSHDG--F 261

Query: 260 DIALDCAGLESTMRLAM 276
           D + DC+G++ T   ++
Sbjct: 262 DYSYDCSGIQVTFETSL 278

ref|YP_098574.1| putative zinc-type alcohol dehydrogenase [Bacteroides fragilis YCH46]
dbj|BAD48040.1| putative zinc-type alcohol dehydrogenase [Bacteroides fragilis YCH46]
(346 aa)

Score: 112 bits (281), Expect: 1.43997e-23
Length: 326, Idn/Pos/Gap = 96/147/32 (29%/45%/9%)

Query:  57 ICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQC 116
           IC SD+H   HGS    R    + +GHE  G+VE +G+GV S++ GDRV +     C +C
Sbjct:  37 ICTSDLHIK-HGSVP--RAVPGITVGHEMVGIVEEVGSGVISVRPGDRVTVNVETFCGEC  93

Query: 117 QRCREGRYNLC--PNIKFFATPPVDGSLARYVCHPAA--WCYRLPESVSLEEGAMC-EPL 171
             CR G  N C  P+  +     +DG  A YV  P A     R+P++VS E+     + L
Sbjct:  94 FFCRHGYVNNCTDPDGGWALGCRIDGGQAEYVRVPYAEQGLNRIPDNVSDEQALFVGDVL 153

Query: 172 SVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAG 231
           +    A R +  +    VL++GAGP G+   +         I+V +    R+ F   H  
Sbjct: 154 ATGFWATRISEISEDDTVLIIGAGPTGICTLLCVMLKKPRRIIVCERSAERIRFVREHY- 212

Query: 232 ADAVI----NTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVVRPGGRICL 287
            D ++    N RD         V    D   AD+ L+ AG E T RLA    RP   + +
Sbjct: 213 PDVLVTEPENCRDF--------VLCNSDHGGADVVLEVAGSEETFRLAWECARPNAIVTI 264

Query: 288 VGMGSSAMHVPLVDASSREIDIFGVFRYSNT----YPTCIALLASGRVNVKPLITHRFMG 343
           V +      +PL D   + +    +F+            ++L+  GR++  PLITHRF  
Sbjct: 265 VALYDKPQFLPLPDMYGKNL----IFKTGGVDGCDCAEILSLIEQGRIDTTPLITHRF-- 318

Query: 344 LEESSLEAAFETARTAANGAVKVMLT 369
              + +E A+        G +K+ +T
Sbjct: 319 -PLNEIEEAYRIFENKLEGVIKIAIT 343

ref|NP_754075.1| Hypothetical zinc-type alcohol dehydrogenase-like protein ydjL [Escherichia coli CFT073]
gb|AAN80640.1| Hypothetical zinc-type alcohol dehydrogenase-like protein ydjL [Escherichia coli CFT073]
gb|AAG56765.1| putative oxidoreductase [Escherichia coli O157:H7 EDL933]
dbj|BAB35908.1| putative oxidoreductase [Escherichia coli O157:H7]
ref|NP_310512.1| putative oxidoreductase [Escherichia coli O157:H7]
pir||E90939 probable oxidoreductase ECs2485 [imported] - Escherichia coli (strain O157:H7, substrain RIMD 0509952)
pir||A85788 probable oxidoreductase Z2815 [imported] - Escherichia coli  (strain O157:H7, substrain EDL933)
ref|NP_288212.1| putative oxidoreductase [Escherichia coli O157:H7 EDL933]
(358 aa)

Score: 112 bits (281), Expect: 1.4642e-23
Length: 350, Idn/Pos/Gap = 103/160/35 (29%/45%/10%)

Query:  40 VPAP--APGEVRLQMRCVGICGSDV-HYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGV  96
           VP P   P +V ++++   ICG+D+ HY        F      I GHE AG +  +G  V
Sbjct:  19 VPQPICGPEDVVIEIKAAAICGADMKHYNVDSGSDEFN----SIRGHEFAGCIAQVGEKV  74

Query:  97 TSLQVGDRVALE-PGVPCLQCQRCREGRYNLCPNIKF---FATPPVDGSLARYVCHP--- 149
              +VG RV  +  G  C  C  C +G + LC   K           G  ++Y   P   
Sbjct:  75 KDWKVGQRVVSDNSGHVCGVCPACEQGDF-LCCTEKVNLGLDNNTWGGGFSKYCLVPGEI 133

Query: 150 ------AAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTI-GSLVLVLGAGPIGLLNC 202
                 A W   +P+ V  E+ A+ +P+  A  +  +    + G  V+V+G GP+GL + 
Sbjct: 134 LKIHRHALW--EIPDGVDYEDAAVLDPICNAYKSIAQQSKFLPGQDVVVIGTGPLGLFSV 191

Query: 203 MVAKAFGASIIVVTDI-DDRRLAF-AETHAGADAVINTRDLDEHDAALVVQQALDGAQAD 260
            +A+  GA  IVV  + +D  + F      GA AV+N       D     QQ        
Sbjct: 192 QMARIMGAVNIVVVGLQEDVAVRFPVAKELGATAVVNG---STEDVVARCQQICGKDNLG 248

Query: 261 IALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRY-SNTY 319
           + ++C+G    ++ A+ ++RP G +  VGMG   +   + D ++    I G   Y S ++
Sbjct: 249 LVIECSGANIALKQAIEMLRPNGEVVRVGMGFKPLDFSINDITAWNKSIIGHMAYDSTSW 308

Query: 320 PTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLT 369
              I LLASG + VKP+ITHR +GL  S     F+        A+KV++T
Sbjct: 309 RNAIRLLASGAIKVKPMITHR-IGL--SQWREGFDA--MVDKTAIKVIMT 353

ref|NP_416290.1| hypothetical zinc-type alcohol dehydrogenase-like protein [Escherichia coli K12]
gb|AAC74846.1| hypothetical zinc-type alcohol dehydrogenase-like protein; putative dehydrogenase, NAD(P)-binding [Escherichia coli K12]
pir||H64937 probable alcohol dehydrogenase (EC 1.1.1.-) - Escherichia coli (strain K-12)
sp|P77539|YDJL_ECOLI Hypothetical zinc-type alcohol dehydrogenase-like protein ydjL
dbj|BAA15574.1| Threonine 3-dehydrogenase (EC 1.1.1.103). [Escherichia coli]
(358 aa)

Score: 112 bits (281), Expect: 1.52658e-23
Length: 350, Idn/Pos/Gap = 103/160/35 (29%/45%/10%)

Query:  40 VPAP--APGEVRLQMRCVGICGSDV-HYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGV  96
           VP P   P +V ++++   ICG+D+ HY        F      I GHE AG +  +G  V
Sbjct:  19 VPQPMCGPEDVVIEIKAAAICGADMKHYNVDSGSDEFN----SIRGHEFAGCIAQVGEKV  74

Query:  97 TSLQVGDRVALE-PGVPCLQCQRCREGRYNLCPNIKF---FATPPVDGSLARYVCHP--- 149
              +VG RV  +  G  C  C  C +G + LC   K           G  ++Y   P   
Sbjct:  75 KDWKVGQRVVSDNSGHVCGVCPACEQGDF-LCCTEKVNLGLDNNTWGGGFSKYCLVPGEI 133

Query: 150 ------AAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTI-GSLVLVLGAGPIGLLNC 202
                 A W   +P+ V  E+ A+ +P+  A  +  +    + G  V+V+G GP+GL + 
Sbjct: 134 LKIHRHALW--EIPDGVDYEDAAVLDPICNAYKSIAQQSKFLPGQDVVVIGTGPLGLFSV 191

Query: 203 MVAKAFGASIIVVTDI-DDRRLAF-AETHAGADAVINTRDLDEHDAALVVQQALDGAQAD 260
            +A+  GA  IVV  + +D  + F      GA AV+N       D     QQ        
Sbjct: 192 QMARIMGAVNIVVVGLQEDVAVRFPVAKELGATAVVNG---STEDVVARCQQICGKDNLG 248

Query: 261 IALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRY-SNTY 319
           + ++C+G    ++ A+ ++RP G +  VGMG   +   + D ++    I G   Y S ++
Sbjct: 249 LVIECSGANIALKQAIEMLRPNGEVVRVGMGFKPLDFSINDITAWNKSIIGHMAYDSTSW 308

Query: 320 PTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLT 369
              I LLASG + VKP+ITHR +GL  S     F+        A+KV++T
Sbjct: 309 RNAIRLLASGAIKVKPMITHR-IGL--SQWREGFDA--MVDKTAIKVIMT 353

sp|P39714|BDH1_YEAST (R,R)-butanediol dehydrogenase
gb|AAC04974.1| Yal060wp [Saccharomyces cerevisiae]
ref|NP_009341.1| Bdh1p [Saccharomyces cerevisiae]
(382 aa)

Score: 112 bits (280), Expect: 1.56527e-23
Length: 257, Idn/Pos/Gap = 81/122/33 (31%/47%/12%)

Query:  47 EVRLQMRCVGICGSDVHYWWHGSCGPFRLHD-----------PMIIGHESAGVVEALGAG  95
           EV + +   GICGSD+H +  G    F   D           P+ +GHE +G+V  +G  
Sbjct:  28 EVIIDVSWCGICGSDLHEYLDGPI--FMPKDGECHKLSNAALPLAMGHEMSGIVSKVGPK  85

Query:  96 VTSLQVGDRVALEPGVPCLQ--------------CQRCREGRYNLCPNIKFFATPPVDGS 141
           VT ++VGD V ++    C                C  C+ G  NLC +  F     + G 
Sbjct:  86 VTKVKVGDHVVVDAASSCADLHCWPHSKFYNSKPCDACQRGSENLCTHAGFVGLGVISGG 145

Query: 142 LARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLN 201
            A  V         +P+ + L+  A+ EPLSV  HA + +G   GS  LVLGAGPIGL  
Sbjct: 146 FAEQVVVSQHHIIPVPKEIPLDVAALVEPLSVTWHAVKISGFKKGSSALVLGAGPIGLCT 205

Query: 202 CMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALV--VQQALDGAQA 259
            +V K  GAS IVV++I +RR+  A+   G + V N          ++  + ++ DG   
Sbjct: 206 ILVLKGMGASKIVVSEIAERRIEMAKK-LGVE-VFNPSKHGHKSIEILRGLTKSHDG--F 261

Query: 260 DIALDCAGLESTMRLAM 276
           D + DC+G++ T   ++
Sbjct: 262 DYSYDCSGIQVTFETSL 278

emb|CAH06994.1| putative zinc-binding alcohol dehydrogenase [Bacteroides fragilis NCTC 9343]
ref|YP_210939.1| putative zinc-binding alcohol dehydrogenase [Bacteroides fragilis NCTC 9343]
(346 aa)

Score: 112 bits (280), Expect: 1.56527e-23
Length: 326, Idn/Pos/Gap = 96/147/32 (29%/45%/9%)

Query:  57 ICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQC 116
           IC SD+H   HGS    R    + +GHE  G+VE +G+GV S++ GDRV +     C +C
Sbjct:  37 ICTSDLHIK-HGSVP--RAVPGITVGHEMVGIVEEVGSGVISVRPGDRVTVNVETFCGEC  93

Query: 117 QRCREGRYNLC--PNIKFFATPPVDGSLARYVCHPAA--WCYRLPESVSLEEGAMC-EPL 171
             CR G  N C  P+  +     +DG  A YV  P A     R+P++VS E+     + L
Sbjct:  94 FFCRHGYVNNCTDPDGGWALGCRIDGGQAEYVRVPYAEQGLNRIPDNVSDEQALFVGDVL 153

Query: 172 SVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAG 231
           +    A R +  +    VL++GAGP G+   +         I+V +    R+ F   H  
Sbjct: 154 ATGFWATRISEISEDDTVLIIGAGPTGICTLLCVMLKKPRRIIVCERSAERIRFVREHY- 212

Query: 232 ADAVI----NTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVVRPGGRICL 287
            D ++    N RD         V    D   AD+ L+ AG E T RLA    RP   + +
Sbjct: 213 PDVLVTEPENCRDF--------VLCNSDHGGADVVLEVAGSEETFRLAWECARPNAIVTI 264

Query: 288 VGMGSSAMHVPLVDASSREIDIFGVFRYSNT----YPTCIALLASGRVNVKPLITHRFMG 343
           V +      +PL D   + +    +F+            ++L+  GR++  PLITHRF  
Sbjct: 265 VALYDKPQFLPLPDMYGKNL----IFKTGGVDGCDCAEILSLIEQGRIDTTPLITHRF-- 318

Query: 344 LEESSLEAAFETARTAANGAVKVMLT 369
              + +E A+        G +K+ +T
Sbjct: 319 -PLNEIEEAYRIFENKLEGVIKIAIT 343

gb|AAV95168.1| alcohol dehydrogenase, zinc-containing [Silicibacter pomeroyi DSS-3]
ref|YP_167126.1| alcohol dehydrogenase, zinc-containing [Silicibacter pomeroyi DSS-3]
(347 aa)

Score: 112 bits (280), Expect: 1.60495e-23
Length: 326, Idn/Pos/Gap = 105/165/26 (32%/50%/7%)

Query:  41 PAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQ 100
           P P PGEV L++   G+C SD H W  G+     L  P++ GHE  G V ALG GV+  +
Sbjct:  21 PTPGPGEVVLRVLACGVCRSDWHAW-TGADPDVEL--PLVPGHEFCGEVVALGTGVSRWR  77

Query: 101 VGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAA--WCYRLPE 158
           +GDRV     + C +C  C  G   +C N +       +G+ A  +  P A      LP+
Sbjct:  78 LGDRVIAPFILACGRCGDCAAGHQTICANQQVPGFTR-NGAFAELIAVPFADTNLTALPD 136

Query: 159 SVS--LEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVT 216
           S+   +  G  C   +       RA    G  + V G G +GL   ++ +A GA ++VV 
Sbjct: 137 SLPPHVAAGLGCRVTTAWQALVGRAELRPGEWLAVFGGGGVGLSALLLGRALGARVVVVD 196

Query: 217 DIDDRRLAFAETHA---GADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMR 273
            ++D+      THA   GADAV+N  D D  +A     + L G  A +A++  G+ +TM 
Sbjct: 197 VVEDKL-----THAKSLGADAVVNAADTDAAEAV----RELTGGGAHVAVEALGIAATMT 247

Query: 274 LAMHVVRPGGRICLVGMGS---SAMHVPLVDASSREIDIFGVFRYSN-TYPTCIALLASG 329
            AM  +R  GR+ ++GM +   +AM +P+    S ++ + G        YP+ ++L+  G
Sbjct: 248 GAMRSLRKLGRLVMIGMPAGEHTAMTLPMDVLYSGQLTLQGTRGMPAWRYPSLLSLIDGG 307

Query: 330 RVNVKPLITHRFMGLEESSLE-AAFE 354
            V++ PL+T R + L ++S E AAF+
Sbjct: 308 HVDLSPLVT-RTIALSQASDELAAFD 332

ref|ZP_00302195.1| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Novosphingobium aromaticivorans DSM 12444]
(347 aa)

Score: 112 bits (279), Expect: 2.58231e-23
Length: 354, Idn/Pos/Gap = 106/158/34 (29%/44%/9%)

Query:  30 PRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFR-LHDPMIIGHESAGV  88
           P ++R+    VP   PGE  +Q+   G+CGSD+ Y   G  G    L  P+ IGHE AG 
Sbjct:  15 PGDVRLDEVPVPHCGPGEALVQVAACGVCGSDLGYIAQGGLGGVEPLSAPLPIGHEFAGT  74

Query:  89 VEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCH 148
           V A+G  VTS+  G RVA+                    P+  +      DG++A ++  
Sbjct:  75 VVAVGQCVTSVAPGMRVAVN-------------------PDRAYIGGGGPDGAMAAFIRV 115

Query: 149 PAA----WCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMV 204
             A      + LP+ +   E ++ EPLSV +H  R AG      + +LGAGPIGL   ++
Sbjct: 116 AGAEIGETLFPLPDHLPFAEASLAEPLSVGLHGLRVAGAKTEDRIAILGAGPIGLCALVM 175

Query: 205 AKAFGASIIVVTDIDDRRLAFAETHAGADAV-INTRDLDEHDAALVVQQALDGAQ---AD 260
           A+  GA  + + D    RL  A       AV +    L E  A         GA+    D
Sbjct: 176 ARHLGARDVAIFDRVPERLERARALGAGLAVDVTQESLTEALARFHGSGERFGAKFVGTD 235

Query: 261 IALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVF--RYSNT 318
           + +DCAG  + +   + V +   RI +V +    + + L    + EI + G      S  
Sbjct: 236 VFVDCAGSAAALEEVVAVAKYRARIAVVALHHKPLALDLWRMMANEISLAGSIADARSEE 295

Query: 319 YPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLTIPE 372
           +   +A+LA+G   + PLI+HRF   + S    A          A KV+LT PE
Sbjct: 296 FGEAVAMLAAGGQALSPLISHRF---DFSRFHEAL-AVAADGARAAKVILTFPE 345

ref|NP_708383.1| putative oxidoreductase [Shigella flexneri 2a str. 301]
gb|AAN44090.1| putative oxidoreductase [Shigella flexneri 2a str. 301]
(364 aa)

Score: 111 bits (278), Expect: 2.71488e-23
Length: 351, Idn/Pos/Gap = 108/156/25 (30%/44%/7%)

Query:  35 VMLRSVPAPAPG--EVRLQMRCVGICGSDVHYWWHGSC----GPFR-LHDPMIIGHESAG  87
           V LR V  P PG  +V ++M+  GICGSDVHY +H  C     P + L+   I GHE  G
Sbjct:  26 VDLREVAVPTPGINQVLIKMKSSGICGSDVHYIYHQHCATAAAPDKPLYQGFINGHEPCG  85

Query:  88 VVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATP-PVDGSLARYV 146
            + A+G G    + GDRV +     C  C  CR G    C      A     DG  A Y+
Sbjct:  86 QIVAMGQGCRHFKEGDRVLVYHISGCGFCPNCRRGFPISCTGKGKAAYGWQRDGGHAEYL 145

Query: 147 CHPAAWCYRLPESVSLEEGAMCE-PLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVA 205
                    LP+++S E+GA     +  A     R   +    VLV+G GP+G++  M+A
Sbjct: 146 LAEEKDLILLPDALSYEDGAFISCGVGTAYEGILRGEVSGSDNVLVVGLGPVGMMAMMLA 205

Query: 206 KAFGASIIVVTDIDDRRLAFAETHAGADA--VINTRDLDEHDAALVVQQALDGAQADIAL 263
           K  GA  I+  D+   RLA A+   G D   +  T  L +     ++ +   G  AD+AL
Sbjct: 206 KGRGAKRIIGVDMLPERLAMAKQLGGMDHGYLATTEGLPQ-----IIAELTHGG-ADVAL 259

Query: 264 DCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTY-PTC 322
           DC+G  +   LA+      GR+  +G           D    +  I G +  S  +   C
Sbjct: 260 DCSGNAAGRLLALQSTADWGRVVYIGETGKVEFEVSADLMHHQRRIIGSWVTSLFHMEKC 319

Query: 323 IALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAV-KVMLTIPE 372
              L   ++  +  ITHRF      SLE A +     A+G   KV++  P+
Sbjct: 320 AHDLTDWKLWPRNAITHRF------SLEQAGDAYVLMASGKCGKVVINFPD 364

ref|ZP_00215044.1| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Burkholderia cepacia R18194]
(351 aa)

Score: 111 bits (278), Expect: 2.80702e-23
Length: 336, Idn/Pos/Gap = 101/147/18 (30%/43%/5%)

Query:  41 PAPAPGEVRLQMRCVGICGSDVHYWWHG---SCGPFRLHDPM-----IIGHESAGVVEAL  92
           P P  GE  ++M+  G+CG+D+HY+ HG   S G   L D M     I GHE  GVV AL
Sbjct:  20 PVPGYGEAVIEMKASGMCGTDLHYYRHGMAESLGMLGLRDRMESAHVIGGHEPCGVVAAL  79

Query:  93 GAGV--TSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPA 150
           G GV   S +VGDRV +     C  C  CR G   LC +          G  A Y+  P 
Sbjct:  80 GPGVDPKSFRVGDRVMVFHYAGCSCCDPCRTGWTQLCDHGARIYGVLSHGGHANYMKVPV 139

Query: 151 AWCYRLPESVSLEEG-AMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFG 209
           +    LP+ VS + G A+      A  A  R   +    + V G GP+GL    +A A G
Sbjct: 140 SSLVHLPQEVSFKGGAAIACGTGTAYGALLRLDISARDTLAVYGLGPVGLSTAQLAAAMG 199

Query: 210 ASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLE 269
             +I V DI+  R+  A+    A  +    D  + D    + +   G     A++CAG E
Sbjct: 200 VEVIGV-DINPHRVERAKAFGVAHGI----DASQCDPVDTIHRLTGGQGVSCAVECAGGE 254

Query: 270 STMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNT-YPTCIALLAS 328
                A+   +  GR+ LV +G +     + D   ++  + G F +S      C   +A 
Sbjct: 255 LPRAQAIRSTKVWGRVVLVAVGGNVTVDAMKDLIGKQRTLIGSFTFSEPGMKECAHFIAD 314

Query: 329 GRVNVKPLITHRFMGLEESSLEAAFETARTAANGAV 364
             V V  L T  +  LE++    A    +T+  G +
Sbjct: 315 HGVEVDRLFTDEWR-LEQAGDAYAHFNRQTSGKGVI 349

gb|AAR99066.1| putative 6-hydroxycaproate dehydrogenase [Brachymonas petroleovorans]
(369 aa)

Score: 111 bits (278), Expect: 3.05128e-23
Length: 282, Idn/Pos/Gap = 91/125/29 (32%/44%/10%)

Query:  29 RPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHD-----PMIIGH  83
           +P   R M   VP P PG   +++    ICGSD+H W HG    F+L       P ++GH
Sbjct:  15 QPFTFREM--PVPDPKPGAAVVRVTMANICGSDLHAW-HGD---FKLAGLGGKLPTVLGH  68

Query:  84 ESAGVVEALGAGVTS------LQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPP 137
           E  G + ALG G  +      L  GD V       C  C  C  G    C  +    T P
Sbjct:  69 EMTGQIVALGEGKHTDGNGQPLHEGDHVVYTYFTGCGHCPMCLRGHRVSCDELTMAMTEP 128

Query: 138 -------VDGSLARYVCHPAAWCYRLPESVSLE--EGAMCEPLSVAVHANRRAGTTIGSL 188
                  V G    Y   P A  Y++P+ +  E   GA C  LS  +    RA  T    
Sbjct: 129 ALEWPYFVGGYADYYYVKPGATIYKVPQGLPDEVVAGANC-ALSQVISGWERAQLTFDET 187

Query: 189 VLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDL-DEHDAA 247
           VL+ GAG +GL  C VAKAFGA +++  D   +RL  A    GADA IN  +L DE    
Sbjct: 188 VLIQGAGGLGLYACAVAKAFGARLVIAIDAVQQRLDMARRF-GADATINLTELPDEKARV 246

Query: 248 LVVQQALDGAQADIALDCAGLESTMRLAMHVVRPGGRICLVG 289
            +V++  DG   D+ ++  G    +   + ++   GR   +G
Sbjct: 247 NLVKKLTDGRGVDVVMELVGRADVVPEGLRMLGQFGRYVTIG 288

ref|NP_707338.1| putative oxidoreductase [Shigella flexneri 2a str. 301]
gb|AAN43045.1| putative oxidoreductase [Shigella flexneri 2a str. 301]
ref|NP_837133.1| putative oxidoreductase [Shigella flexneri 2a str. 2457T]
gb|AAP16940.1| putative oxidoreductase [Shigella flexneri 2a str. 2457T]
(358 aa)

Score: 111 bits (278), Expect: 3.40086e-23
Length: 350, Idn/Pos/Gap = 103/159/35 (29%/45%/10%)

Query:  40 VPAP--APGEVRLQMRCVGICGSDV-HYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGV  96
           VP P   P +V  +++   ICG+D+ HY        F      I GHE AG +  +G  V
Sbjct:  19 VPQPICGPEDVVTEIKAAAICGADMKHYNVDSGSDEFN----SIRGHEFAGCIAQVGEKV  74

Query:  97 TSLQVGDRVALE-PGVPCLQCQRCREGRYNLCPNIKF---FATPPVDGSLARYVCHP--- 149
              +VG RV  +  G  C  C  C +G + LC   K           G  ++Y   P   
Sbjct:  75 KDWKVGQRVVSDNSGHVCGVCPACEQGDF-LCCTEKVNLGLDNNTWGGGFSKYCLVPGEI 133

Query: 150 ------AAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTI-GSLVLVLGAGPIGLLNC 202
                 A W   +P+ V  E+ A+ +P+  A  +  +    + G  V+V+G GP+GL + 
Sbjct: 134 LKIHRHALW--EIPDGVDYEDAAVLDPICNAYKSIAQQSKFLPGQDVVVIGTGPLGLFSV 191

Query: 203 MVAKAFGASIIVVTDI-DDRRLAF-AETHAGADAVINTRDLDEHDAALVVQQALDGAQAD 260
            +A+  GA  IVV  + +D  + F      GA AV+N       D     QQ        
Sbjct: 192 QMARIMGAVNIVVVGLQEDVAVRFPVAKELGATAVVNG---STEDVVARCQQICGKDNLG 248

Query: 261 IALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRY-SNTY 319
           + ++C+G    ++ A+ ++RP G +  VGMG   +   + D ++    I G   Y S ++
Sbjct: 249 LVIECSGANIALKQAIEMLRPNGEVVRVGMGFKPLDFSINDITAWNKSIIGHMAYDSTSW 308

Query: 320 PTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAVKVMLT 369
              I LLASG + VKP+ITHR +GL  S     F+        A+KV++T
Sbjct: 309 RNAIRLLASGAIKVKPMITHR-IGL--SQWREGFDA--MVDKTAIKVIMT 353

ref|NP_104464.1| L-iditol 2-dehydrogenase (EC 1.1.1.14) [Mesorhizobium loti MAFF303099]
dbj|BAB50250.1| L-iditol 2-dehydrogenase [Mesorhizobium loti MAFF303099]
(338 aa)

Score: 111 bits (277), Expect: 3.60541e-23
Length: 313, Idn/Pos/Gap = 98/146/13 (31%/46%/4%)

Query:  30 PRELRVMLRSVP-APAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGV  88
           P EL +  R  P AP  G   + +  VGICG+D H +      PF L  P I+GHE +G 
Sbjct:   9 PGELVLEDRPAPGAPPAGWALVAVSHVGICGTDYHIFEGKH--PF-LAYPRIMGHEVSGT  65

Query:  89 VEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCH 148
           V   G G   L +G+ V + P + C +C  CR G+ N C  I+       DG++   +  
Sbjct:  66 VIETGEG-PDLAIGEPVVINPYLSCGKCIACRHGKPNCCVKIEVLGVHR-DGAMCERILV 123

Query: 149 PAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAF 208
           PA   Y     +SL + A  E L++  HA RRA    G+  LV+GAGPIGL N + A+  
Sbjct: 124 PAQNLYP-ANGLSLADAAAVEFLAIGAHAVRRARADSGARALVIGAGPIGLGNAIFARIA 182

Query: 209 GASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGL 268
           G  + ++ D+   RLAFAE   G   +  +R         +V+ A  G   D+  D  G 
Sbjct: 183 GLDVTLL-DMSSERLAFAENELGFSILDGSRGA----VPDLVKDATSGEGFDVVFDATGN 237

Query: 269 ESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFR-YSNTYPTCIALLA 327
             +++ A   V  GG + LV +    +     +   RE+ + G        +    A + 
Sbjct: 238 TRSVQSAFAHVAHGGTLVLVSVVKDDIVFSDPEFHKREMTLVGSRNALRADFDHVAASIR 297

Query: 328 SGRVNVKPLITHR 340
           +G V +  L+THR
Sbjct: 298 NGAVPLAKLVTHR 310

emb|CAC14943.1| putative oxidoreductase [Streptomyces coelicolor A3(2)]
ref|NP_625045.1| putative oxidoreductase [Streptomyces coelicolor A3(2)]
(362 aa)

Score: 110 bits (276), Expect: 4.78805e-23
Length: 327, Idn/Pos/Gap = 95/152/29 (29%/46%/8%)

Query:  33 LRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEAL  92
           +R+    VP P PGE  ++++  G+C +D+HY   G    F    P ++GHE+AGVVE++
Sbjct:  17 VRIETIVVPDPGPGEAVVKIQACGVCHTDLHYKQGGINDEF----PFLLGHEAAGVVESV  72

Query:  93 GAGVTSLQVGDRVALEPGVPCLQCQRCREGR-------YNLCPNIKFFAT-----PPVD- 139
           GAGVT +  GD V L     C +C+ CR GR       +N    +   +T     P +  
Sbjct:  73 GAGVTDVAPGDFVILNWRAVCGKCRACRRGRPWYCFDTHNAEQRMTLASTGQELSPALGI 132

Query: 140 GSLARYVCHPAAWCYRLPESVSLEEGAM--CEPLSVAVHANRRAGTTIGSLVLVLGAGPI 197
           G+ A      A  C ++  +V  E   +  C  ++    A        G  V V+G G +
Sbjct: 133 GAFAEKTLVAAGQCTKVDPAVPAEVAGLLGCGVMAGIGAAINTGNVGRGDTVAVIGCGGV 192

Query: 198 GLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGA 257
           G      +   GAS ++  DIDDR+L  A T  GA   +N+R  D  +A   +++   G 
Sbjct: 193 GDAAIAGSYLAGASKVIAVDIDDRKLETART-MGATHTVNSRGTDPVEA---IRELTGGF 248

Query: 258 QADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAM--HVPLVDASSR----EIDIFG 311
            AD+ ++  G   T R A +     G + LVG+ +  M   +PL+D   R    +   +G
Sbjct: 249 GADVVIEAVGRPETYRQAFYARDLAGTVVLVGVPTPEMKLELPLLDVFGRGGSLKSSWYG 308

Query: 312 VFRYSNTYPTCIALLASGRVNVKPLIT 338
               S  +P  + L   GR+++   +T
Sbjct: 309 DCLPSRDFPMLVDLHLQGRLDLGKFVT 335

ref|ZP_00147045.2| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Psychrobacter sp. 273-4]
(364 aa)

Score: 110 bits (276), Expect: 5.61058e-23
Length: 345, Idn/Pos/Gap = 90/160/43 (26%/46%/12%)

Query:  26 VLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHES  85
           + + P ++ V  + +P   P +  +++    ICG+D+H +     G + +   + IGHE 
Sbjct:   8 IFIEPGKIEVAEKKIPDVGPNDALIKITTTTICGTDIHIFK----GEYPVAKGLTIGHEP  63

Query:  86 AGVVEALGAGVTSLQVGDRV---ALEPGVPCLQCQR---CREGRY----NLCPNIKFFAT 135
            G++E LG+ V   Q G RV   A+ P       Q     ++G Y      C    + AT
Sbjct:  64 VGIIEKLGSAVMGYQEGQRVIAGAICPSFTSYASQDGFPSQDGGYIQPDGTCACHGYKAT 123

Query: 136 PP------VDGSLARYVCHPAAWC--YRLPESVSLEEGAMC-EPLSVAVHANRRAGTTIG 186
                   +DG+ A YV  P A      +P+ ++ E+  MC + +S        A   IG
Sbjct: 124 GGWRFGNIIDGTQAEYVLVPDAQANLAPVPDGLTDEQVLMCPDIMSTGFKGAENANIKIG 183

Query: 187 SLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDA 246
            +V +   GPIGL     AK  GAS I+  D ++ RLA ++   GAD  +N +++D  D 
Sbjct: 184 DIVAIFAQGPIGLCATAGAKLRGASTIIAIDGNNERLAMSKK-LGADITLNFKEVDVVDE 242

Query: 247 ALVVQQALDGAQADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSRE 306
              + +   G   D +++  GL+ST    + V++PGG +  +G+ S+ + +P+   +S  
Sbjct: 243 ---IMKITGGRGVDSSIEALGLQSTFEQGIKVLKPGGTLSSLGVYSADLKIPMAYFAS-- 297

Query: 307 IDIFGVFRYSNTYPTC----------IALLASGRVNVKPLITHRF 341
               G+  ++     C          + ++ SGRV+   ++TH +
Sbjct: 298 ----GLGDHTIRTALCPGGKERMRRLLNVVESGRVDFSEMVTHTY 338

emb|CAD73222.1| sorbitol dehydrogenase [Rhodopirellula baltica SH 1]
ref|NP_865538.1| sorbitol dehydrogenase [Rhodopirellula baltica SH 1]
(414 aa)

Score: 110 bits (275), Expect: 5.89861e-23
Length: 370, Idn/Pos/Gap = 104/161/57 (28%/43%/15%)

Query:  27 LVRPRELRVMLRSVPAPAPGEVR-------------LQMRCVGICGSDVHYWWHGSCGPF  73
           + +P  +R +  ++ AP   E+R             L++   GICG+D H +  G     
Sbjct:  28 VAKPESVRAV--AMTAPGATEMRTYPYPTVDHDSAILKVDMSGICGTDRHIF-KGEASEL  84

Query:  74 RLHD--PMIIGHESAGVVEALGAGVTS--------LQVGDRVALEPGVPCLQCQRCRE-- 121
           R     P + GHE  G +  +G             LQVGDRVA+   V C  C  CR+  
Sbjct:  85 RGKSIFPYVGGHEVIGTIVEIGDNAAKVMDYDKQPLQVGDRVAIAVEVNCGHCFYCRKHY 144

Query: 122 ---------GRYNLCPNIKFFATPPVDGSLARYV-CHPAAWCYRLPESVSLEEGAMCEPL 171
                      Y L PN      P + G  A Y+   P    +++P+ +S +     E +
Sbjct: 145 NNTTCLNQIQAYGLHPNAD--TLPYLRGGFAEYIFIRPGTHLFKVPDEMSTDVAVFVEEM 202

Query: 172 SVAVHANRRA---------GTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRR 222
           +VA H+  RA         G   G+ V VLG GP+G+L+ ++A   GA + + TD+ D R
Sbjct: 203 AVAYHSLARAAGPFAPVNEGFGPGNSVAVLGNGPLGILHGIMASIHGAGLRIATDLSDLR 262

Query: 223 LAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVVRPG 282
           L  A+ +  AD  IN   +   +    V+   +G   D+ ++ AG       A+ +VR G
Sbjct: 263 LEKAK-NLYADVTINAAKVSTDERIEQVKDMTEGVGPDLVIESAGEPEAFIEALRMVRKG 321

Query: 283 GRICLVG----MGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALL--ASGRVNVKPL 336
           G +  VG    +G       +   SS+ + I  VF     +   + +L   S R +   L
Sbjct: 322 GTVIEVGNWVDLGKPVALDVMRHISSKNLHIHSVFHCGTDWRPVLNILHQQSDRYDFPSL 381

Query: 337 ITHRFMGLEE 346
           ITHRF GL+E
Sbjct: 382 ITHRF-GLDE 390

ref|NP_663841.1| putative alcohol dehydrogenase I [Streptococcus pyogenes MGAS315]
gb|AAM78644.1| putative alcohol dehydrogenase I [Streptococcus pyogenes MGAS315]
(338 aa)

Score: 110 bits (275), Expect: 6.68505e-23
Length: 283, Idn/Pos/Gap = 86/139/16 (30%/49%/5%)

Query:  33 LRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCG--PFRLHDPMIIGHESAGVVE  90
           + V+   +P    GE  +++   G+C +D+H   HG  G  P R     I+GHE  G+VE
Sbjct:  13 VEVVEHDLPNVGHGEALVKVEYCGVCHTDLHVA-HGDFGQVPGR-----ILGHEGIGIVE  66

Query:  91 ALGAGVTSLQVGDRVALEPGVP-CLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHP 149
            +G GVTSL+VGDRV++      C  C+ C  GR  LC ++K  A   VDG ++ Y    
Sbjct:  67 EIGEGVTSLKVGDRVSIAWFFEGCGHCEYCTTGRETLCRSVK-NAGYSVDGGMSEYAVVT 125

Query: 150 AAWCYRLPESVSLEEGAMCEPLSVAVH-ANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAF 208
           A +  ++PE +   + +      V  + A + AG   G  +++ GAG +G L    AK  
Sbjct: 126 ADYAVKVPEGLDPAQASSITCAGVTTYKAIKEAGAAPGQWIVIFGAGGLGNLAVQYAKKV 185

Query: 209 GASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGL 268
             + +V  DI++ +L  A+   GAD V+N ++++  D    +Q+   GA   +    A  
Sbjct: 186 FNAHVVAVDINNDKLELAK-EVGADIVVNGKEIE--DVPGYIQEKTGGAHGVVV--TAVS 240

Query: 269 ESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFG 311
           +     A+  VR GG +  VG+ S  M + +V      I + G
Sbjct: 241 KVAFNQAIDSVRAGGTVVAVGLPSEYMELSIVKTVLDGIKVVG 283

gb|AAL96873.1| putative alcohol dehydrogenase I [Streptococcus pyogenes MGAS8232]
ref|NP_606374.1| putative alcohol dehydrogenase I [Streptococcus pyogenes MGAS8232]
(338 aa)

Score: 110 bits (274), Expect: 7.70383e-23
Length: 283, Idn/Pos/Gap = 84/140/16 (29%/49%/5%)

Query:  33 LRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCG--PFRLHDPMIIGHESAGVVE  90
           + V+   +P    GE  +++   G+C +D+H   HG  G  P R     I+GHE  G+VE
Sbjct:  13 VEVVEHDLPNVGHGEALVKVEYCGVCHTDLHVA-HGDFGQVPGR-----ILGHEGIGIVE  66

Query:  91 ALGAGVTSLQVGDRVALEPGVP-CLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHP 149
            +G GVTSL+VGDRV++      C  C+ C  GR  LC ++K  A   VDG ++ Y    
Sbjct:  67 EIGEGVTSLKVGDRVSIAWFFEGCGHCEYCTTGRETLCRSVK-NAGYSVDGGMSEYAVVT 125

Query: 150 AAWCYRLPESVSLEEGAMCEPLSVAVH-ANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAF 208
           A +  ++PE +   + +      V  + A + AG   G  +++ GAG +G L    AK  
Sbjct: 126 ADYAVKVPEGLDPAQASSITCAGVTTYKAIKEAGVAPGQWIVIFGAGGLGNLAVQYAKKV 185

Query: 209 GASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGL 268
             + +V  DI++ +L  A+   GAD ++N ++++  D    +Q+ + GA   +    + +
Sbjct: 186 FNAHVVAVDINNDKLELAK-EVGADILVNGKEIE--DVPGYIQEKIGGAHGVVVTAVSKV 242

Query: 269 ESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFG 311
                 A+  VR GG +  VG+ S  M + +V      I + G
Sbjct: 243 --AFNQAIDSVRAGGTVVAVGLPSEYMELSIVKTVLDGIKVVG 283

ref|YP_059408.1| Alcohol dehydrogenase [Streptococcus pyogenes MGAS10394]
gb|AAT86225.1| Alcohol dehydrogenase [Streptococcus pyogenes MGAS10394]
(338 aa)

Score: 110 bits (274), Expect: 8.09931e-23
Length: 283, Idn/Pos/Gap = 85/140/16 (30%/49%/5%)

Query:  33 LRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCG--PFRLHDPMIIGHESAGVVE  90
           + V+   +P    GE  +++   G+C +D+H   HG  G  P R     I+GHE  G+VE
Sbjct:  13 VEVVEHDLPNVGHGEALVKVEYCGVCHTDLHVA-HGDFGQVPGR-----ILGHEGIGIVE  66

Query:  91 ALGAGVTSLQVGDRVALEPGVP-CLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHP 149
            +G GVTSL+VGDRV++      C  C+ C  GR  LC ++K  A   VDG ++ Y    
Sbjct:  67 EIGEGVTSLKVGDRVSIAWFFEGCGHCEYCTTGRETLCRSVK-NAGYSVDGGMSEYAVVT 125

Query: 150 AAWCYRLPESVSLEEGAMCEPLSVAVH-ANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAF 208
           A +  ++PE +   + +      V  + A + AG   G  +++ GAG +G L    AK  
Sbjct: 126 ADYAVKVPEGLDPAQASSITCAGVTTYKAIKEAGAAPGQWIVIFGAGGLGNLAVQYAKKV 185

Query: 209 GASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGL 268
             + +V  DI++ +L  A+   GAD ++N ++++  D    +Q+ + GA   +    A  
Sbjct: 186 FNAHVVAVDINNDKLELAK-EVGADILVNGKEIE--DVPGYIQEKIGGAHGVVV--TAVS 240

Query: 269 ESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFG 311
           +     A+  VR GG +  VG+ S  M + +V      I + G
Sbjct: 241 KVAFNQAIDSVRAGGTVVAVGLPSEYMELSIVKTVLDGIKVVG 283

gb|AAP74382.1| mixed alcohol dehydrogenase Adh8b [Danio rerio]
gb|AAH71367.1| Alcohol dehydrogenase 8b [Danio rerio]
ref|NP_982285.1| alcohol dehydrogenase 8b [Danio rerio]
(376 aa)

Score: 110 bits (274), Expect: 8.73094e-23
Length: 363, Idn/Pos/Gap = 98/165/37 (26%/45%/10%)

Query:  11 SDAGSVLNEKANPCGVLVRPRELRVMLR-SVPAPAPGEVRLQMRCVGICGSDVHYWWHGS  69
           + AG V+  +A    V   P+   VM    V  P  GEVR+++    +C +D+ +    +
Sbjct:   2 ATAGKVIKCRA---AVAWEPKAPLVMEEIEVAPPQEGEVRIKILYTSLCHTDLFHLLEST  58

Query:  70 CGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCP- 128
                   P I+GHE+AGVVE++G GVT  + GD+V    G  C +C+ C+  R NLC  
Sbjct:  59 DNK---GFPTILGHEAAGVVESVGPGVTEFKPGDKVIPNSGCQCRECKFCKSPRTNLCER 115

Query: 129 -----NIKFFATPPVD--------------GSLARYVCHPAAWCYRLPESVSLEEGAM-- 167
                +I++ + P                 G+LA Y+     +  ++ +   L+   +  
Sbjct: 116 SWVNDHIEYMSYPKTSFTCRGKPILQFTNTGTLAEYIVIRQIYVVKIDDDAPLDRVCLLG 175

Query: 168 CEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFAE 227
           C   +    A   AG T GS+  V G G +GL   M  K  GAS I   DI++++   A+
Sbjct: 176 CGVTTGYGAAVNSAGVTPGSVCAVFGLGAVGLAAVMGCKNAGASRIFAVDINEKKFEKAK 235

Query: 228 THAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVVRPG-GRIC 286
              GA   +N +  ++  + ++++    G   D +L+C G     RLA+     G G   
Sbjct: 236 VF-GATDFLNPKAYNKPISEVLIEMTNGG--VDFSLECVGNTEVSRLALESCAKGWGLSV 292

Query: 287 LVGMGS---SAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASGRVNVKPLITHRFMG 343
           LVG  +   S+  + L+   + +  + G F+  +  P  +    SG++ +   IT R M 
Sbjct: 293 LVGYTNTDFSSKPIQLIYGKTWKGTLLGGFKIKDGVPKLVLDYMSGKIMLDEFITQR-MK 351

Query: 344 LEE 346
           LE+
Sbjct: 352 LEQ 354

ref|YP_055629.1| putative zinc-binding sorbitol dehydrogenase [Propionibacterium acnes KPA171202]
gb|AAT82671.1| putative zinc-binding sorbitol dehydrogenase [Propionibacterium acnes KPA171202]
(348 aa)

Score: 110 bits (274), Expect: 9.41183e-23
Length: 322, Idn/Pos/Gap = 91/144/22 (28%/44%/6%)

Query:  30 PRELRVMLRSVPAP--APGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAG  87
           P ++R  L  VP P     E+++++R    CG+DV    +G      +    I+GHE AG
Sbjct:   9 PEDVR--LEDVPEPECKSDEIKIKVRNCSTCGTDVKILHNGHQN---ITGVTIMGHEVAG  63

Query:  88 VVEALGAGVT-SLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLARYV 146
            +  +G+ V    ++GDRV     VPC QC  CR+G   +C N +       DG  A Y+
Sbjct:  64 EIVEIGSEVAGDWKIGDRVQSIAAVPCGQCHECRKGWMQVCQN-QTSVGYQYDGGFAEYM 122

Query: 147 CHPAA-----WCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLN 201
             P          R+P+ V  +E +  EP + A++A  + G   G  + + GAGPIG ++
Sbjct: 123 IVPPQVLKVDGLNRIPDDVDFDEASAAEPFACAINAQEQLGIEKGDFLAIFGAGPIGCMH 182

Query: 202 CMVAKAF-GASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQAD 260
             +A+       IV+ DI+  RLA +      D  I   D  + D    V +  +G  AD
Sbjct: 183 TRIARGVHKVGTIVMIDINAERLALSAAAVKPDITI---DGSQEDVVAKVMELTNGRGAD 239

Query: 261 IALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDAS---SREIDIFGVFRYSN 317
           + +       T   A+ +    GRI   G           D++    R++ I G    + 
Sbjct: 240 VIITATPANITQEQALSMAARNGRISFFGGLPKTNPTITCDSNLIHYRQLHIHGANGSAP 299

Query: 318 TY-PTCIALLASGRVNVKPLIT 338
            +    +  +ASG+V VK LIT
Sbjct: 300 EHNKRALQYIASGQVPVKDLIT 321

dbj|BAC74664.1| putative alcohol dehydrogenase [Streptomyces avermitilis MA-4680]
ref|NP_828129.1| putative alcohol dehydrogenase [Streptomyces avermitilis MA-4680]
(363 aa)

Score: 109 bits (273), Expect: 1.1692e-22
Length: 297, Idn/Pos/Gap = 96/138/36 (32%/46%/12%)

Query:  30 PRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVV  89
           P E++ ++  VP P PGEV + ++  G+C +D+HY        F    P ++GHE+AG V
Sbjct:  18 PVEVQTIV--VPDPGPGEVLVAVQACGVCHTDLHYREGAITDDF----PFLLGHEAAGTV  71

Query:  90 EALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLC--------PNIKFFATPPVD-- 139
           EA+GAGVT L  GD V L    PC  C+ CR GR   C        P      TP  +  
Sbjct:  72 EAVGAGVTDLAPGDYVVLAWRAPCGSCRSCRRGRPWYCFDSRNATQPMTLLDGTPLSNAL 131

Query: 140 --GSLARYVCHPAAWCYRL-----PESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVL 192
             G+ A      A    ++     PE+  L    +      AV+  +      G  V V+
Sbjct: 132 GIGAFAEKTLVAAGQAVKIDPAARPEAAGLIGCGVMAGYGAAVNTGK---VGRGDTVAVI 188

Query: 193 GAGPIGLLNCMVAKAF--GASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVV 250
           G G +G  N  +A A   GA  ++  DIDD++L  AE   GA   +N+R  D  +A   V
Sbjct: 189 GCGGVG--NAAIAGACLNGAMKVIAVDIDDKKLDQAEKF-GATHTVNSRGTDPVEA---V 242

Query: 251 QQALDGAQADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHV--PLVDASSR 305
           +   DG   DIA+D  G   T + A ++    G +  VG+    M +  PL+D  SR
Sbjct: 243 RALTDGFGVDIAIDAVGRPETYKQAFYMRDHAGTLVQVGVPDPEMKIDLPLIDLFSR 299

ref|ZP_00170327.2| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Ralstonia eutropha JMP134]
(337 aa)

Score: 109 bits (272), Expect: 1.32508e-22
Length: 301, Idn/Pos/Gap = 83/136/32 (27%/45%/10%)

Query:  26 VLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDP-----MI  80
           V  +P  + V+ R +P   PGE+ L++   GICGSD+H  +HG       HDP     ++
Sbjct:   5 VYTQPDAVEVLDRDMPDLEPGEILLRIDASGICGSDLHA-YHG-------HDPRRKPGLV  56

Query:  81 IGHESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDG 140
           +GHE AG V A  +    + VG RV   P V C  C  C +GR NLC N +        G
Sbjct:  57 LGHEFAGTVIA-SSDEARMPVGQRVTANPLVTCGHCDYCLQGRDNLCAN-RGMVGMNRPG 114

Query: 141 SLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGS-----LVLVLGAG 195
           +L+ Y+  P      +P+++     A+ EP + A+HA       +        VL++G G
Sbjct: 115 ALSEYLAIPIRCAIPIPDTLPSVSAALTEPAATALHAVNLTMRAMSRPLPEVSVLIIGGG 174

Query: 196 PIGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALD 255
            IG+L   +  ++G   + V + +  R A    H G + +  T       A         
Sbjct: 175 AIGMLTAALVTSYGCKRVCVAETNALRQASVSRHLGCEVIDPTVSPPPESA--------- 225

Query: 256 GAQADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRY 315
               D+ +D  G   T  LA+   RPGG +  +G+ + +  + +   +  E+ + G + Y
Sbjct: 226 ---FDVVIDAVGAAPTRNLAIAATRPGGVVMHIGLQAWSSEIDMRKLTLAELTLLGTYTY 282

Query: 316 S 316
           +
Sbjct: 283 T 283

ref|NP_838105.1| putative oxidoreductase [Shigella flexneri 2a str. 2457T]
gb|AAP17915.1| putative oxidoreductase [Shigella flexneri 2a str. 2457T]
(364 aa)

Score: 109 bits (272), Expect: 1.41655e-22
Length: 351, Idn/Pos/Gap = 107/156/25 (30%/44%/7%)

Query:  35 VMLRSVPAPAPG--EVRLQMRCVGICGSDVHYWWH----GSCGPFR-LHDPMIIGHESAG  87
           V LR V  P PG  +V ++M+  GICGSDVHY +H     +  P + L+   I GHE  G
Sbjct:  26 VDLREVAVPTPGINQVLIKMKSSGICGSDVHYIYHQHRATAAAPDKPLYQGFINGHEPCG  85

Query:  88 VVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATP-PVDGSLARYV 146
            + A+G G    + GDRV +     C  C  CR G    C      A     DG  A Y+
Sbjct:  86 QIVAMGQGCRHFKEGDRVLVYHISGCGFCPNCRRGFPISCTGKGKAAYGWQRDGGHAEYL 145

Query: 147 CHPAAWCYRLPESVSLEEGAMCE-PLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVA 205
                    LP+++S E+GA     +  A     R   +    VLV+G GP+G++  M+A
Sbjct: 146 LAEEKDLILLPDALSYEDGAFISCGVGTAYEGILRGEVSGSDNVLVVGLGPVGMMAMMLA 205

Query: 206 KAFGASIIVVTDIDDRRLAFAETHAGADA--VINTRDLDEHDAALVVQQALDGAQADIAL 263
           K  GA  I+  D+   RLA A+   G D   +  T  L +     ++ +   G  AD+AL
Sbjct: 206 KGRGAKRIIGVDMLPERLAMAKQLGGMDHGYLATTEGLPQ-----IIAELTHGG-ADVAL 259

Query: 264 DCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTY-PTC 322
           DC+G  +   LA+      GR+  +G           D    +  I G +  S  +   C
Sbjct: 260 DCSGNAAGRLLALQSTADWGRVVYIGETGKVEFEVSADLMHHQRRIIGSWVTSLFHMEKC 319

Query: 323 IALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAV-KVMLTIPE 372
              L   ++  +  ITHRF      SLE A +     A+G   KV++  P+
Sbjct: 320 AHDLTDWKLWPRNAITHRF------SLEQAGDAYVLMASGKCGKVVINFPD 364

ref|NP_250809.1| alcohol dehydrogenase (Zn-dependent) [Pseudomonas aeruginosa PAO1]
gb|AAG05507.1| alcohol dehydrogenase (Zn-dependent) [Pseudomonas aeruginosa PAO1]
pir||A83381 alcohol dehydrogenase (Zn-dependent) PA2119 [imported] - Pseudomonas aeruginosa (strain PAO1)
(366 aa)

Score: 109 bits (272), Expect: 1.64611e-22
Length: 351, Idn/Pos/Gap = 93/158/53 (26%/45%/15%)

Query:  25 GVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHE  84
            V ++P  + ++ + +P   P +  +++    +CG+DVH       G + +   + +GHE
Sbjct:   8 AVFIQPGRIELVDKPIPDVGPNDALVRITTTTLCGTDVHILK----GEYPVAPGLTVGHE  63

Query:  85 SAGVVEALGAGVTSLQVGDRV------------ALEPGVPC------LQCQRCREGRYNL 126
             G++E LG+ V   + G RV            A + GVP       ++  RC    Y  
Sbjct:  64 PVGIIEKLGSAVVGYREGQRVIAGAICPNFNSYAAQDGVPSQDGSYLVESGRCACHGYKA 123

Query: 127 CPNIKFFATPPVDGSLARYVCHPAAWC--YRLPESVSLEEGAMC-EPLSVAVHANRRAGT 183
               +F     +DG+ A YV  P A      +P+ +S E+  MC + +S        A  
Sbjct: 124 TAGWRFGNL--IDGTQAEYVLVPDAQANLAPIPDGLSDEQVLMCPDIMSTGFKGAENANI 181

Query: 184 TIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDE 243
            IG  V +   GPIGL     A+  GAS I+  D +  RL  A    GAD  +N R+ D 
Sbjct: 182 RIGDSVAIFAQGPIGLCATAGARLLGASTIIAIDGNAHRLDIARG-MGADVTLNFRECD- 239

Query: 244 HDAALVVQQALD---GAQADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLV 300
                V+++ L    G   D +++  G +ST   A+ V++PGG +  +G+ S  + +PL 
Sbjct: 240 -----VIEEILKLTGGRGVDASIEALGTQSTFETALRVLKPGGTLSSLGVYSEDLTIPLS 294

Query: 301 DASSREIDIFGVFRYSNTYPTC----------IALLASGRVNVKPLITHRF 341
             ++      G+  +      C          + ++ASGRVN+ PL++H +
Sbjct: 295 AFAA------GLGDHRINTALCPGGKERMRRLLNIVASGRVNLGPLVSHEY 339

ref|NP_353648.1| hypothetical protein AGR_C_1112 [Agrobacterium tumefaciens str. C58]
ref|NP_531326.1| alcohol dehydrogenase [Agrobacterium tumefaciens str. C58]
gb|AAL41642.1| alcohol dehydrogenase [Agrobacterium tumefaciens str. C58]
gb|AAK86433.1| AGR_C_1112p [Agrobacterium tumefaciens str. C58]
pir||AD2653 alcohol dehydrogenase adhP [imported] - Agrobacterium tumefaciens (strain C58, Dupont)
pir||H97434 alcohol dehydrogenase [imported] - Agrobacterium tumefaciens (strain C58, Cereon)
(342 aa)

Score: 108 bits (271), Expect: 1.71623e-22
Length: 281, Idn/Pos/Gap = 91/131/24 (32%/46%/8%)

Query:  39 SVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCG--PFRLHDPMIIGHESAGVVEALGAGV  96
           ++P P PGE+ +  +  G+C +D+H     + G  P + + P I GHE AG V  +GAGV
Sbjct:  23 AIPDPGPGEILINYKATGVCHTDLH----AATGDWPVKPNPPFIPGHEGAGYVAKIGAGV  78

Query:  97 TSLQVGDRVALEPGVP-----CLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAA 151
           T ++ GDR     G P     C  C  CR G   LCP+ K  +   V+GS A Y      
Sbjct:  79 TGIKEGDRA----GTPWLYTACGCCIPCRTGWETLCPSQK-NSGYSVNGSFAEYGLADPK 133

Query: 152 WCYRLPESVSLEEGAMCEPLSVAVHAN-RRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGA 210
           +  RLP+++     A      V V+   +      G  V++ G G +G +    AKA G 
Sbjct: 134 FVGRLPDNLDFGPAAPVLCAGVTVYKGLKETEVRPGEWVVISGIGGLGHMAVQYAKAMGM 193

Query: 211 SIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLES 270
             +V  DI D +LA A+   GAD V+N R     DA   VQ+A  G     AL  A    
Sbjct: 194 H-VVAADIFDDKLALAKK-LGADVVVNGR---APDAVEQVQKATGGVHG--ALVTAVSPK 246

Query: 271 TMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFG 311
            M  A   +R  G + LVG+    + +P+ D   + I + G
Sbjct: 247 AMEQAYGFLRSKGTMALVGLPPGFISIPVFDTVLKRITVRG 287

pir||A30196 probable alcohol dehydrogenase (EC 1.1.1.1) - Alcaligenes eutrophus
sp|P14940|ADH_ALCEU Alcohol dehydrogenase
gb|AAA21953.1| alcohol dehydrogenase (EC 1.1.1.1)
(366 aa)

Score: 108 bits (271), Expect: 1.77448e-22
Length: 373, Idn/Pos/Gap = 99/169/46 (26%/45%/12%)

Query:  25 GVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHE  84
            V V P  + +  + +P   P +  +++    ICG+DVH       G + +   + +GHE
Sbjct:   8 AVFVEPGRIELADKPIPDIGPNDALVRITTTTICGTDVHILK----GEYPVAKGLTVGHE  63

Query:  85 SAGVVEALGAGVTSLQVGDRV---ALEPGVPCLQCQ---RCREGRYNL----CPNIKFFA 134
             G++E LG+ VT  + G RV   A+ P       Q     ++G Y +    C    + A
Sbjct:  64 PVGIIEKLGSAVTGYREGQRVIAGAICPNFNSYAAQDGVASQDGSYLMASGQCGCHGYKA 123

Query: 135 TPP------VDGSLARYVCHPAAWC--YRLPESVSLEEGAMC-EPLSVAVHANRRAGTTI 185
           T        +DG+ A YV  P A      +P+ ++ E+  MC + +S        A   I
Sbjct: 124 TAGWRFGNMIDGTQAEYVLVPDAQANLTPIPDGLTDEQVLMCPDIMSTGFKGAENANIRI 183

Query: 186 GSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHD 245
           G  V V   GPIGL     A+  GA+ I+  D +D RL  A    GAD V+N R+ D  D
Sbjct: 184 GHTVAVFAQGPIGLCATAGARLCGATTIIAIDGNDHRLEIARK-MGADVVLNFRNCDVVD 242

Query: 246 AALVVQQALDGAQADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSR 305
               V +   G   D +++  G ++T   ++ V++PGG +  +G+ SS + +PL   ++ 
Sbjct: 243 E---VMKLTGGRGVDASIEALGTQATFEQSLRVLKPGGTLSSLGVYSSDLTIPLSAFAA- 298

Query: 306 EIDIFGVFRYSNTYPTC----------IALLASGRVNVKPLITHRFMGLEESSLEAAFET 355
                G+  +      C          I ++ SGRV++  L+TH++       + AA++ 
Sbjct: 299 -----GLGDHKINTALCPGGKERMRRLINVIESGRVDLGALVTHQY---RLDDIVAAYDL 350

Query: 356 ARTAANGAVKVML 368
                +G +K+ +
Sbjct: 351 FANQRDGVLKIAI 363

gb|AAK33179.1| putative alcohol dehydrogenase I [Streptococcus pyogenes M1 GAS]
ref|NP_268457.1| putative alcohol dehydrogenase I [Streptococcus pyogenes M1 GAS]
(338 aa)

Score: 108 bits (271), Expect: 1.89697e-22
Length: 283, Idn/Pos/Gap = 84/139/16 (29%/49%/5%)

Query:  33 LRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCG--PFRLHDPMIIGHESAGVVE  90
           + V+   +P    GE  +++   G+C +D+H   HG  G  P R     I+GHE  G+VE
Sbjct:  13 VEVVEHDLPNIGHGEALVKVEYCGVCHTDLHVA-HGDFGQVPGR-----ILGHEGIGIVE  66

Query:  91 ALGAGVTSLQVGDRVALEPGVP-CLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHP 149
            +G GVTSL+VGDRV++      C  C+ C  GR  LC ++K  A   VDG ++ Y    
Sbjct:  67 EIGEGVTSLKVGDRVSIAWFFEGCGHCEYCTTGRETLCRSVK-NAGYSVDGGMSEYAVVT 125

Query: 150 AAWCYRLPESVSLEEGAMCEPLSVAVH-ANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAF 208
           A +  ++PE +   + +      V  + A + AG   G  +++ GAG +G L    AK  
Sbjct: 126 ADYAVKVPEGLDPAQASSITCAGVTTYKAIKEAGAAPGQWIVIFGAGGLGNLAVQYAKKV 185

Query: 209 GASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGL 268
             + +V  DI++ +L  A+   GAD ++N ++++  D    +Q+   GA   +    + +
Sbjct: 186 FNAHVVAVDINNDKLELAK-EVGADILVNGKEIE--DVPGYIQEKTGGAHGVVVTAVSKV 242

Query: 269 ESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFG 311
                 A+  VR GG +  VG+ S  M + +V      I + G
Sbjct: 243 --AFNQAIDSVRAGGTVVAVGLPSEYMELSIVKTVLDGIKVVG 283

dbj|BAD95818.1| dehydrogenase [Streptomyces fradiae]
(340 aa)

Score: 108 bits (270), Expect: 2.6931e-22
Length: 321, Idn/Pos/Gap = 93/149/18 (28%/46%/5%)

Query:  26 VLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYW---WHGSCGPFRLHDPMIIG  82
           V   P    +  R +PAPAPGE  +++    +CGSD+ ++   WHG         P++ G
Sbjct:   5 VFEAPERAVLTHRDIPAPAPGEALVRVAYNSVCGSDLSFYKGVWHG------FTYPVVPG  58

Query:  83 HESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSL 142
           HE +G V  +     +  VG  V  +    C  C  C  G   LC ++        DG+ 
Sbjct:  59 HEWSGSVVDVNGPRGADLVGRNVVGDLTCSCGTCAHCAAGTPTLCEDLGELGFTR-DGAC 117

Query: 143 ARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNC 202
           A Y+  P A    LP+++ L      EPL+VA++A  R G T G  V V+GAG IGLL  
Sbjct: 118 AEYMTVPVANLRPLPDTLPLRTACQVEPLAVALNAVDRLGVTPGEKVAVMGAGGIGLLLV 177

Query: 203 MVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIA 262
              +  G ++  V +    R A A    G  A +      +  A + + ++   A  D+ 
Sbjct: 178 QAVRLRGGTVTAVAEPVPERRA-AALALGVPAAVG----GDPGALVELTRSDPAAVPDVV 232

Query: 263 LDCAGLESTMRLAMHVVRPGGRICLVG--MGSSAMHVPLVDASSREIDIFGVFRYSNTYP 320
           L+ +G  + ++ A+  VRPGGR+ LVG  +  +A+  P      + + +         + 
Sbjct: 233 LEASGYPTAVQEAVEAVRPGGRVGLVGYRIEEAAVMAPH-HIVLKVLTVRASMGPGTRFE 291

Query: 321 TCIALLASGRVNVKPLITHRF 341
             + +LASG V+V  L++H F
Sbjct: 292 EAVDVLASGAVDVDALLSHEF 312

gb|AAH77635.1| Adh6-prov protein [Xenopus laevis]
(378 aa)

Score: 108 bits (269), Expect: 3.05216e-22
Length: 330, Idn/Pos/Gap = 92/152/36 (27%/46%/10%)

Query:  40 VPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSL  99
           V  P   EVR++M   GIC SD H+   G     +   P+I+GHE  G+VE++G GV  +
Sbjct:  29 VAPPKAHEVRIKMIATGICRSD-HHSIEGKFSSVKF--PVIVGHEGVGIVESIGEGVKDI  85

Query: 100 QVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPV--DGSLARYVCHPAAWCYRLP 157
           + GD+V       C QCQ C++ R N C  IK      +  DG+ +R+ C      Y   
Sbjct:  86 KPGDKVIPLVTPQCGQCQCCKDPRANRCLTIKLERQYGLMADGT-SRFTCR-GKQIYHFL 143

Query: 158 ESVSLEEGAMCEPLSVAVHANRRA---------------GTTI-------GSLVLVLGAG 195
            + +  E  + E ++VA   +                  G+ I       GS  ++ G G
Sbjct: 144 NTSTFTEYTVVEEIAVAKIDDTATMDSVCLIGCAFSTGYGSVINTAKVHPGSTCVIFGLG 203

Query: 196 PIGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALD 255
            IGL   M  K  GA  I+  D++  +   A+   GA   IN +D D+  A ++V+Q   
Sbjct: 204 GIGLAVIMGCKIAGAGRIIGVDVNPDKFDKAK-ELGATECINPKDYDKPVAQVIVEQT-- 260

Query: 256 GAQADIALDCAGLESTMRLAMHVVRPG-GRICLVGMGSSAMHV-PLVDASSREI--DIFG 311
           G   D A +C G   TM  A+H      G   ++G+ +S +   P++  S R +   + G
Sbjct: 261 GGGVDYAFECVGHAETMLAALHSSHFAYGTTVIIGVSASTLSFDPMILLSGRTLKSSMLG 320

Query: 312 VFRYSNTYPTCIALLASGRVNVKPLITHRF 341
            ++  ++ P  ++   + + +++ L+THR 
Sbjct: 321 GWKSKDSVPKLVSDYLAKKFDLEKLVTHRL 350

ref|ZP_00207596.1| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Rhodobacter sphaeroides 2.4.1]
(330 aa)

Score: 108 bits (269), Expect: 3.12953e-22
Length: 316, Idn/Pos/Gap = 97/139/23 (30%/43%/7%)

Query:  26 VLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHES  85
           V V P       R  P   PG +R+++  VGICG+D H +  G   PF L  P I+GHE 
Sbjct:   8 VCVEPGRFEQQDRPRPEAKPGHIRIRILQVGICGTDYHIY--GGHQPF-LAYPRIMGHEL  64

Query:  86 AG-VVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLAR 144
           +G  +EA   G   +  GD V + P + C  C+ CR G+ N C NI        DG +  
Sbjct:  65 SGRAMEASADG--RIAEGDLVVINPYLTCGTCRACRAGKPNCCENIAVLGVH-TDGGMCE 121

Query: 145 YVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMV 204
            +  P    Y   E ++ +  AM E L++  H  RR G   GS  LV+GAGPIG+   + 
Sbjct: 122 EIVVPEGNVYG-AEGLTEQSAAMVEFLAIGAHGVRRGGVRAGSAALVVGAGPIGIGAALF 180

Query: 205 AKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALD 264
           A   GA+ + + D    RLA A+           + L E    LV ++A +    D   D
Sbjct: 181 AAIEGAA-VTLRDTSASRLALAQ-----------KVLLEARIELVGEEAAE--VYDTVFD 226

Query: 265 CAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFR-YSNTYPTCI 323
             G    M   +  V  GG   L+ +    +     +   RE  +F         +   I
Sbjct: 227 ATGNIRAMNAGLQYVGHGGAYVLLSVVKGDLSFADPEFHKREATLFASRNALKKDFEHVI 286

Query: 324 ALLASGRVNVKPLITH 339
           A + +GRV V+ L TH
Sbjct: 287 AQIRNGRVPVEALATH 302

ref|ZP_00380936.1| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Brevibacterium linens BL2]
(328 aa)

Score: 108 bits (269), Expect: 3.40185e-22
Length: 296, Idn/Pos/Gap = 90/130/29 (30%/43%/9%)

Query:  27 LVRPRELRVMLRSVPAP--APGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHE  84
           +  P  + ++ RS+P      G++R++M  VGICG+D      G   P +L  P  +GHE
Sbjct:   6 ITAPGRVEIVDRSLPQGLVGRGDLRIRMLAVGICGTD-QTLATGRRTPPQL--PWRLGHE  62

Query:  85 SAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATPPVDGSLAR 144
             G +  +G G     VGDRVALEP + C +C+ CR G  + C +          G LA 
Sbjct:  63 GIGEIAEVGPGACGFAVGDRVALEPNITCGRCEYCRRGMTSACTSRLSAGVLTQPGFLAE 122

Query: 145 YVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMV 204
            V HP+ +C+RL   +SLE     EPL+VA  A RR        VLVLGAG  GLL+ + 
Sbjct: 123 VVDHPSEFCHRLDAHMSLERAVCAEPLAVAASAIRRTDLQGSETVLVLGAGAQGLLSILT 182

Query: 205 AKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQA---DI 261
             A G    V    D+RR    E  A                     Q     Q+   ++
Sbjct: 183 LVAQGHHPYVSEPDDERRQLAVELGA---------------------QVFTPGQSPAPEV 221

Query: 262 ALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSN 317
            +D AG+   +   +  + P   + LVG     +         R++ I G F Y +
Sbjct: 222 VIDAAGVPEALGAVVDHLAPFAAVTLVGEDHHHLGASSFSIVQRQLRIKGSFIYEH 277

ref|YP_146584.1| alcohol dehydrogenase [Geobacillus kaustophilus HTA426]
dbj|BAD75016.1| alcohol dehydrogenase [Geobacillus kaustophilus HTA426]
(336 aa)

Score: 107 bits (268), Expect: 4.71018e-22
Length: 278, Idn/Pos/Gap = 85/135/22 (30%/48%/7%)

Query:  41 PAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQ 100
           P    GEV +++   G+C +D+H   HG   P +   P+I GHE  G+V  +G GV S+Q
Sbjct:  21 PKLGYGEVLVKIEACGVCHTDLHAA-HGDW-PVKPKLPLIPGHEGVGIVVEIGEGVKSIQ  78

Query: 101 VGDRVALEPGVP-----CLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHPAAWCYR 155
           +GDRV    G+P     C +C+ C  G+  LCP+ +      VDGS A Y   PA +  R
Sbjct:  79 IGDRV----GIPWLYSACGECEYCLSGQETLCPH-QLNGGYSVDGSYAEYCKAPANYVAR 133

Query: 156 LPESVSLEEGA--MCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASII 213
           +P+++   + A  +C  ++    A + +    G  V + G G +G +    AKA G +++
Sbjct: 134 IPKNLDPVQVAPILCAGVT-TYKALKVSNAKPGEWVAIYGIGGLGHIALQYAKAMGLNVV 192

Query: 214 VVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMR 273
            V DI D +   A    GAD  IN     + D    +++ + G QA  A+  A  +    
Sbjct: 193 AV-DISDEKAELA-AKLGADITINGL---QEDPVAAIREKVGGVQA--AISVAVTKKAFE 245

Query: 274 LAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFG 311
            A   VR GG + +VG+    + +P+ D     + I G
Sbjct: 246 QAYQSVRRGGCLVIVGLPHDELPIPIFDTVLNGVTIKG 283

emb|CAH01943.1| unnamed protein product [Kluyveromyces lactis NRRL Y-1140]
ref|XP_451550.1| unnamed protein product [Kluyveromyces lactis]
(386 aa)

Score: 107 bits (268), Expect: 4.82957e-22
Length: 308, Idn/Pos/Gap = 83/142/28 (26%/46%/9%)

Query:  50 LQMRCVGICGSDVHYWWHGSC----------GPFRLHDPMIIGHESAGVVEALGAGVTSL  99
           ++M    ICG+DV  W   S           G F   +  ++GHE  G+V  +G  V ++
Sbjct:  60 IKMTNTSICGTDVGIWKGKSPEIEEIAVKNEGSF---NGRVLGHEGTGIVTEVGDAVRNI 116

Query: 100 QVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATP-PVDGSLARYVCHPAA--WCYRL 156
           + GD+V +     C  C+ C  G Y  C N   +A    +DG+ A YV  P A    Y L
Sbjct: 117 KKGDKVIISCITRCGTCENCARGMYAHCMNDGGWALGYSIDGTQAEYVRTPFADTSLYAL 176

Query: 157 PESVSLEEGAMCEPLSVAVHANRRAGTTIGSL-----VLVLGAGPIGLLNCMVAKAFGAS 211
           PE +S E   +   LS A+      G  +G++     V +LGAGP+G+   + ++ +  S
Sbjct: 177 PEGLSDENAVL---LSDALPTAHEIGVQMGNVKPGDSVAILGAGPVGMGCVLTSQLYSPS 233

Query: 212 IIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLEST 271
           +++V D+DD RL  A+   GA   IN+    + DA   + +  +G   D A++  G + T
Sbjct: 234 LLIVVDMDDNRLEMAK-EMGATHTINS---GKEDAVAKILEITNGRGVDCAMEAVGAQPT 289

Query: 272 MRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASGRV 331
             +   +++ GG +  VG+    +   +     + + I      +NT    +    SG++
Sbjct: 290 WDICQQIIKEGGHLANVGVHGKPVDFAIDKLWIKNLTITSGLVNTNTTSMLMKNCCSGKL 349

Query: 332 NVKPLITH 339
               L++H
Sbjct: 350 QSDKLVSH 357

dbj|BAD32688.1| glycerol dehydrogenase [Pichia angusta]
(380 aa)

Score: 107 bits (267), Expect: 4.95198e-22
Length: 275, Idn/Pos/Gap = 86/128/35 (31%/46%/12%)

Query:  39 SVPAPA---PGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHD------------PMIIGH  83
           +VP P    P +V++++   GICG+D+  + + S GP                 P+  GH
Sbjct:  17 TVPEPEIKNPNDVKIKVSYCGICGTDLKEFTY-SGGPVFFPKQGTKDKISGYELPLCPGH  75

Query:  84 ESAGVVEALGAGVTSLQVGDRVALEPGVPCLQ--------------CQRCREGRYNLCPN 129
           E +G V  +G+GVTS++ GDRVA+E    C                C  C+ G  N C +
Sbjct:  76 EFSGTVVEVGSGVTSVKPGDRVAVEATSHCSDRSRYKDTVAQDLGLCMACQSGSPNCCAS 135

Query: 130 IKFFATPPVDGSLARYVCHPAAWCYRLPESVSLEEGAMCEPLSVAVHANRRAGTTIGSLV 189
           + F       G  A YV +      +LP+S+  + GA+ EP+SVA HA  RA    G   
Sbjct: 136 LSFCGLGGASGGFAEYVVYGEDHMVKLPDSIPDDIGALVEPISVAWHAVERARFQPGQTA 195

Query: 190 LVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAAL- 248
           LVLG GPIGL   +  +   A  IV ++    R  FA+   GA+ V +    D+ +A L 
Sbjct: 196 LVLGGGPIGLATILALQGHHAGKIVCSEPALIRRQFAK-ELGAE-VFDPSTCDDANAVLK 253

Query: 249 VVQQALDGAQADIALDCAGLESTMRLAMHVVRPGG 283
            +    +G  A  A DC+G+  T   ++    P G
Sbjct: 254 AMVPENEGFHA--AFDCSGVPQTFTTSIVATGPSG 286

ref|ZP_00281764.1| COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Burkholderia fungorum LB400]
(366 aa)

Score: 107 bits (267), Expect: 5.33816e-22
Length: 373, Idn/Pos/Gap = 100/164/46 (26%/43%/12%)

Query:  25 GVLVRPRELRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHE  84
            V + P  + +  + VP     +  +++    ICG+DVH       G + +   + +GHE
Sbjct:   8 AVFIEPGRIELADKPVPDVGANDALVRITTTTICGTDVHILK----GEYPVAKGLTVGHE  63

Query:  85 SAGVVEALGAGVTSLQVGDRV------------ALEPGVPCLQCQRCREGRY----NLCP 128
             GV+E LG+ V   Q G RV            A + GVP       ++G Y     LC 
Sbjct:  64 PVGVIEKLGSAVLGYQEGQRVVAGAICPNFNSYAAQDGVPS------QDGSYLIARGLCG 117

Query: 129 NIKFFATPP------VDGSLARYVCHPAAWC--YRLPESVSLEEGAMC-EPLSVAVHANR 179
              + AT        +DG+ A YV  P A      +P+ ++ E+  MC + +S       
Sbjct: 118 CHGYKATAGWRFGNMIDGTQAEYVLVPDAQANLAPVPDGLTDEQVLMCPDIMSTGFKGAE 177

Query: 180 RAGTTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTR 239
            A   IG  V V   GPIGL     A+  GAS I+  D +D RL  A    GAD  +N +
Sbjct: 178 NANIRIGDTVAVFAQGPIGLCATAGARLLGASTIIAVDGNDHRLEIARK-MGADVTLNFK 236

Query: 240 DLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPL 299
           + D  D  L   +   G   D +++  G +ST   A+ +++PGG +  +G+ SS + +PL
Sbjct: 237 NCDVVDEIL---KLTGGRGVDSSIEALGTQSTFESALRILKPGGTLSSLGVYSSDLTIPL 293

Query: 300 ----VDASSREIDIFGVFRYSNTYPTCIALLASGRVNVKPLITHRFMGLEESSLEAAFET 355
                     +I+              + ++ SGRV++  L+TH +   +   + AA++ 
Sbjct: 294 GAFAAGLGDHKINTALCPGGKERMRRLLNVVESGRVDLGALVTHHY---KLDDIVAAYDL 350

Query: 356 ARTAANGAVKVML 368
                +G +KV +
Sbjct: 351 FANQRDGVLKVAI 363

emb|CAD45699.1| Unknown [Streptococcus agalactiae NEM316]
ref|NP_734524.1| hypothetical protein gbs0054 [Streptococcus agalactiae NEM316]
(338 aa)

Score: 106 bits (265), Expect: 9.9808e-22
Length: 283, Idn/Pos/Gap = 85/135/16 (30%/47%/5%)

Query:  33 LRVMLRSVPAPAPGEVRLQMRCVGICGSDVHYWWHGSCG--PFRLHDPMIIGHESAGVVE  90
           + V+   +P    GE  +++   G+C +D+H   HG  G  P R     I+GHE  G+VE
Sbjct:  13 VEVVEHDLPKVGHGEALVKVEYCGVCHTDLHVA-HGDFGQVPGR-----ILGHEGIGIVE  66

Query:  91 ALGAGVTSLQVGDRVALEPGVP-CLQCQRCREGRYNLCPNIKFFATPPVDGSLARYVCHP 149
            +G GVTSL+VGDRV++      C  C+ C  GR  LC ++K  A   VDG ++ Y    
Sbjct:  67 EIGEGVTSLRVGDRVSIAWFFEGCGHCEYCTTGRETLCRSVK-NAGYSVDGGMSEYAVVT 125

Query: 150 AAWCYRLPESVSLEEGAMCEPLSVAVH-ANRRAGTTIGSLVLVLGAGPIGLLNCMVAKAF 208
           A +  ++PE +   + +      V  + A + AG   G  + V GAG +G L    AK  
Sbjct: 126 ADYAVKVPEGLDPAQASSITCAGVTTYKAIKEAGAAPGQWIAVYGAGGLGNLAVQYAKKV 185

Query: 209 GASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGL 268
             + +V  DI+  +L  A+   GAD  +N +++   D A  +Q+   G    +    + +
Sbjct: 186 FNAHVVAVDINADKLQLAK-EVGADLTVNGKEIK--DVAAYIQEKTGGCHGVVVTAVSKV 242

Query: 269 ESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFG 311
                 A+  VR GG +  VG+ S  M + +V      I + G
Sbjct: 243 --AFNQAIDSVRAGGTVVAVGLPSEYMELSIVKTVLDGIRVVG 283

ref|NP_789376.1| alcohol dehydrogenase [Tropheryma whipplei TW08/27]
emb|CAD67114.1| alcohol dehydrogenase [Tropheryma whipplei TW08/27]
(356 aa)

Score: 106 bits (265), Expect: 1.00644e-21
Length: 332, Idn/Pos/Gap = 90/150/16 (27%/45%/4%)

Query:  47 EVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGDRVA 106
           +V L+M    ICGSD+H    G     +     ++GHE  G +  +G  V S  VGDRV 
Sbjct:  29 DVILEMETTTICGSDLHIL-KGDVAAVK--PGTVLGHEGIGKIVEVGKDVKSHSVGDRVI  85

Query: 107 LEPGVPCLQCQRCREGRYNLCPNIK-----FFATPPVDGSLARYVCHPAA--WCYRLPES 159
           + P   C  C+ CR      C         +     ++G  A++   P A    ++LP  
Sbjct:  86 VSPMSSCGVCRFCRANNNGHCLGDSEGPGGWRLGGLINGVQAQFARIPLADNSLHKLPSG 145

Query: 160 VSLEEGAMC-EPLSVAVHANRRAG-TTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTD 217
           +  + G +  + L        +AG  T+GS+V V+G GP+GL   + +  +  S ++  D
Sbjct: 146 LDPKVGILVSDVLPTGHEVGAQAGQVTLGSVVAVIGCGPVGLGAIVTSLLYSPSKVIAVD 205

Query: 218 IDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMH 277
            D  RL  A      D V   R+        V +    G   D+A++  G+  T  +A+ 
Sbjct: 206 ADSNRLELARKLGATDTVRVNRERPLDAIEDVKKLTEGGFGVDVAIEAVGVPVTFSMALG 265

Query: 278 VVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASGRVNVKPLI 337
           +  PGGR+  +G+  + +  PL D   + I +      ++T P  +A L+ G+++    +
Sbjct: 266 IAAPGGRVANIGVHGAPVDFPLQDLWDKNIAVTLGIVSTHTIPLLLAALSEGKIDASQFV 325

Query: 338 THRFMGLEESSLEAAFETARTAA-NGAVKVML 368
           TH F   + S LE A++    AA +  VKV +
Sbjct: 326 THEF---DLSDLERAYDVFSAAAQHNVVKVAI 354

gb|AAO44423.1| zinc-type alcohol dehydrogenase [Tropheryma whipplei str. Twist]
ref|NP_787454.1| zinc-type alcohol dehydrogenase [Tropheryma whipplei str. Twist]
(357 aa)

Score: 106 bits (265), Expect: 1.00644e-21
Length: 332, Idn/Pos/Gap = 90/150/16 (27%/45%/4%)

Query:  47 EVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVEALGAGVTSLQVGDRVA 106
           +V L+M    ICGSD+H    G     +     ++GHE  G +  +G  V S  VGDRV 
Sbjct:  30 DVILEMETTTICGSDLHIL-KGDVAAVK--PGTVLGHEGIGKIVEVGKDVKSHSVGDRVI  86

Query: 107 LEPGVPCLQCQRCREGRYNLCPNIK-----FFATPPVDGSLARYVCHPAA--WCYRLPES 159
           + P   C  C+ CR      C         +     ++G  A++   P A    ++LP  
Sbjct:  87 VSPMSSCGVCRFCRANNNGHCLGDSEGPGGWRLGGLINGVQAQFARIPLADNSLHKLPSG 146

Query: 160 VSLEEGAMC-EPLSVAVHANRRAG-TTIGSLVLVLGAGPIGLLNCMVAKAFGASIIVVTD 217
           +  + G +  + L        +AG  T+GS+V V+G GP+GL   + +  +  S ++  D
Sbjct: 147 LDPKVGILVSDVLPTGHEVGAQAGQVTLGSVVAVIGCGPVGLGAIVTSLLYSPSKVIAVD 206

Query: 218 IDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALDCAGLESTMRLAMH 277
            D  RL  A      D V   R+        V +    G   D+A++  G+  T  +A+ 
Sbjct: 207 ADSNRLELARKLGATDTVRVNRERPLDAIEDVKKLTEGGFGVDVAIEAVGVPVTFSMALG 266

Query: 278 VVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTYPTCIALLASGRVNVKPLI 337
           +  PGGR+  +G+  + +  PL D   + I +      ++T P  +A L+ G+++    +
Sbjct: 267 IAAPGGRVANIGVHGAPVDFPLQDLWDKNIAVTLGIVSTHTIPLLLAALSEGKIDASQFV 326

Query: 338 THRFMGLEESSLEAAFETARTAA-NGAVKVML 368
           TH F   + S LE A++    AA +  VKV +
Sbjct: 327 THEF---DLSDLERAYDVFSAAAQHNVVKVAI 355

ref|NP_417040.1| putative dehydrogenase, NAD(P)-binding [Escherichia coli K12]
gb|AAC75598.1| putative oxidoreductase; putative dehydrogenase, NAD(P)-binding [Escherichia coli K12]
pir||H65031 hypothetical protein b2545 - Escherichia coli (strain K-12)
dbj|BAA16454.1| SORBITOL DEHYDROGENASE (EC 1.1.1.14) (L-IDITOL 2-DEHYDROGENASE). [Escherichia coli]
dbj|BAA16447.1| SORBITOL DEHYDROGENASE (EC 1.1.1.14) (L-IDITOL 2-DEHYDROGENASE). [Escherichia coli]
(364 aa)

Score: 106 bits (265), Expect: 1.07592e-21
Length: 354, Idn/Pos/Gap = 106/154/21 (29%/43%/5%)

Query:  30 PRELRVMLRSVPAPAPG--EVRLQMRCVGICGSDVHYWWH----GSCGPFR-LHDPMIIG  82
           P    V LR V  P PG  +V ++M+  GICGSDVHY +H     +  P + L+   I G
Sbjct:  21 PGNSTVDLREVAVPTPGINQVLIKMKSSGICGSDVHYIYHQHRATAAAPDKPLYQGFING  80

Query:  83 HESAGVVEALGAGVTSLQVGDRVALEPGVPCLQCQRCREGRYNLCPNIKFFATP-PVDGS 141
           HE  G + A+G G    + GDRV +     C  C  CR G    C      A     DG 
Sbjct:  81 HEPCGQIVAMGQGCRHFKEGDRVLVYHISGCGFCPNCRRGFPISCTGEGKAAYGWQRDGG 140

Query: 142 LARYVCHPAAWCYRLPESVSLEEGAMCE-PLSVAVHANRRAGTTIGSLVLVLGAGPIGLL 200
            A Y+         LP+++S E+GA     +  A     R   +    VLV+G GP+G++
Sbjct: 141 HAEYLLAEEKDLILLPDALSYEDGAFISCGVGTAYEGILRGEVSGSDNVLVVGLGPVGMM 200

Query: 201 NCMVAKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQAD 260
             M+AK  GA  I+  D+   RLA A+       V++   L   +    +   L    AD
Sbjct: 201 AMMLAKGRGAKRIIGVDMLPERLAMAKQL----GVMDHGYLATTEGLPQIIAELTHGGAD 256

Query: 261 IALDCAGLESTMRLAMHVVRPGGRICLVGMGSSAMHVPLVDASSREIDIFGVFRYSNTY- 319
           +ALDC+G  +   LA+      GR+  +G           D    +  I G +  S  + 
Sbjct: 257 VALDCSGNAAGRLLALQSTADWGRVVYIGETGKVEFEVSADLMHHQRRIIGSWVTSLFHM 316

Query: 320 PTCIALLASGRVNVKPLITHRFMGLEESSLEAAFETARTAANGAV-KVMLTIPE 372
             C   L   ++  +  ITHRF      SLE A +     A+G   KV++  P+
Sbjct: 317 EKCAHDLTDWKLWPRNAITHRF------SLEQAGDAYALMASGKCGKVVINFPD 364

ref|NP_343845.1| Alcohol dehydrogenase (Zn containing) (adh-9) [Sulfolobus solfataricus P2]
gb|AAK42635.1| Alcohol dehydrogenase (Zn containing) (adh-9) [Sulfolobus solfataricus P2]
pir||D90422 alcohol dehydrogenase (Zn containing) (adh-9) [imported] - Sulfolobus solfataricus
(348 aa)

Score: 106 bits (265), Expect: 1.09402e-21
Length: 319, Idn/Pos/Gap = 100/159/20 (31%/49%/6%)

Query:  33 LRVMLRSVPAPAP--GEVRLQMRCVGICGSDVHYWWHGSCGPFRLHDPMIIGHESAGVVE  90
           L + +  VP PAP  GEV +++   GIC SD+H       GP  L +  IIGHE AG VE
Sbjct:  11 LPLEIEEVPNPAPKEGEVLVKVASTGICHSDLHLLSGELVGP--LPNGFIIGHEIAGWVE  68

Query:  91 ALGAGVTS---LQVGDRVALEPGVPCLQCQRCREGRYNLCPN--IKFFATPPVDGSLARY 145
            +G  V +   L+ GD V +   VPC  C+ C  G+ N C +   +      ++G  A Y
Sbjct:  69 KIGENVKNPYGLKEGDPVLVSWIVPCGICRYCANGKENYCKDNAKRLVGLIGINGGHAEY 128

Query: 146 VCHPAAWCYRLPESVS-LEEGAMCEPLSVAVHANRRAGTTIGSLVLVLGAGPIGLLNCMV 204
           +  P      L +++       +      A +A + A  T G  V+++GAG +G     +
Sbjct: 129 LTVPEIAVIPLAKNLDPYYSSPIACAYGTAYNALKSANATSGKSVVIVGAGGVGSAAIQL 188

Query: 205 AKAFGASIIVVTDIDDRRLAFAETHAGADAVINTRDLDEHDAALVVQQALDGAQADIALD 264
           A + G + IV  DID+ +L  A+   GA  +IN    +E+DA   V +AL+   ADI  +
Sbjct: 189 ANSIGLNPIVAVDIDENKLKSAKL-LGATHIINA---NENDARAKVLEALEDG-ADIVYE 243

Query: 265 CAGLESTMRLAMHVVRPGGRICLVGMG--SSAMHVPLVDASSREIDIFGVFRYSN--TYP 320
                   +L++ VV+ GG I + G+G  S+   +P+    SR I + G   Y      P
Sbjct: 244 TKPYPD-FKLSLEVVKSGGTIVVTGLGGFSTLAQIPVTLFVSRGITLIGSLGYRPRIDLP 302

Query: 321 TCIALLASGRVNVKPLITH 339
             ++L +SG++++K L++H
Sbjct: 303 DLVSLASSGKIDIKKLVSH 321

Cyanidioschyzon merolae Genome Project