BLAST output

CML077C (377 aa)
by blastp 2.2.10 [Oct-19-2004] against nr [Apr-30-2005] (XML result)


		transcription initiation factor IIB [Guillardia theta]
		ENSANGP00000020059 [Anopheles gambiae str. PEST]
		transcription initiation factor IIB [Dictyostelium discoideum]
		general transcription factor II B [Oreochromis mossambicus]
		CG5193-PA [Drosophila melanogaster]
		similar to Transcription initiation factor IIB (General transcription factor TFIIB) [Apis mellifera]
		PREDICTED: similar to kynurenine aminotransferase III [Pan troglodytes]
		General transcription factor IIB [Danio rerio]
		unnamed protein product [Tetraodon nigroviridis]
		PREDICTED: similar to Transcription initiation factor IIB (General transcription factor TFIIB) (S300-II) [Canis familiaris]
		S300-II; TFIIB [Homo sapiens]
		general transcription factor IIB [Rattus norvegicus]
		GA18726-PA [Drosophila pseudoobscura]
		PREDICTED: similar to Transcription initiation factor IIB (General transcription factor TFIIB) (S300-II) [Bos taurus]
		hypothetical protein LOC549031 [Xenopus tropicalis]
		TFIIB [Xenopus laevis]
		PREDICTED: similar to Transcription initiation factor IIB (General transcription factor TFIIB) (RNA polymerase II alpha initiation factor) [Gallus gallus]
		likely transcription factor TFIIB [Candida albicans SC5314]
		Tfii(two)b (general transcription factor) protein 1 [Caenorhabditis elegans]
		unnamed protein product [Debaryomyces hansenii CBS767]
		Hypothetical protein CBG06439 [Caenorhabditis briggsae]
		SPAC16E8.16 [Schizosaccharomyces pombe]
		unnamed protein product [Candida glabrata CBS138]
		YPR086W [Saccharomyces cerevisiae]
		Sua7p: Transcription initiation factor IIB (Swiss Prot. accession number P29055) [Saccharomyces cerevisiae]
		unnamed protein product [Yarrowia lipolytica CLIB99]
		LOC494830 protein [Xenopus laevis]
		TRANSCRIPTION INITIATION FACTOR TFIIB [Encephalitozoon cuniculi GB-M1]
		ADR007Cp [Ashbya gossypii ATCC 10895]
		PREDICTED: similar to Transcription initiation factor IIB (General transcription factor TFIIB) (S300-II), partial [Bos taurus]
		TF2B_KLULA [Kluyveromyces lactis NRRL Y-1140]
		TFIIB1 [Arabidopsis thaliana]
		general transcription factor IIB [Homo sapiens]
		general transcription factor IIB [Homo sapiens]
		transcription initiation factor iib, putative [Cryptococcus neoformans var. neoformans JEC21]
		hypothetical protein CNBF2750 [Cryptococcus neoformans var. neoformans B-3501A]
		transcription initiation factor iib, putative [Cryptococcus neoformans var. neoformans JEC21]
		transcription initiation factor TFIIB [Antonospora locustae]
		transcription factor TFIIB [Glycine max]
		general transcription factor TFIIB [Oryza sativa]
		TFIIB2 [Arabidopsis thaliana]
		Transcription initiation factor IIB (General transcription factor TFIIB)
		AtTFIIB2 [Arabidopsis thaliana]
		hypothetical protein FG00597.1 [Gibberella zeae PH-1]
		hypothetical protein [Neurospora crassa]
		hypothetical protein AN4928.2 [Aspergillus nidulans FGSC A4]
		likely transcription factor TFIIB [Candida albicans SC5314]
		hypothetical protein UM04794.1 [Ustilago maydis 521]
		ENSANGP00000020018 [Anopheles gambiae str. PEST]
		transcription initiation factor IIB related protein [Thermoplasma acidophilum DSM 1728]
		hypothetical protein MG05370.4 [Magnaporthe grisea 70-15]
		COG1405: Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB [Ferroplasma acidarmanus]
		transcription initiation factor IIB [Pyrococcus horikoshii OT3]
		TATA box binding protein TFIIB-BBRE complex, chain B [Pyrococcus abyssi GE5]
		Transcription initiation factor IIB [Thermoplasma volcanium GSS1]
		transcription initiation factor IIB [Picrophilus torridus DSM 9790]
		putative transcription initiation factor IIB (TFIIB) [Oryza sativa (japonica cultivar-group)]
		transcription initiation factor IIB [Archaeoglobus fulgidus DSM 4304]
		putative transcription initiation factor IIB [Acanthamoeba polyphaga mimivirus]
		transcription factor IIB - Pyrococcus woesei
		transcription initiation factor IIB chain b [Pyrococcus furiosus DSM 3638]
		TfbG [Halobacterium sp. NRC-1]
		Chain Q, Crystal Structure Of A Human Tbp Core Domain-Human Tfiib Core Domain Complex Bound To An Extended, Modified Adenoviral Major Late Promoter (Admlp)
		transcription initiation factor IIB [Thermococcus kodakaraensis KOD1]
		transcription initiation factor TFIIB [Methanothermobacter thermautotrophicus str. Delta H]
		Nmr Studies Of Human General Transcription Factor Tfiib: Dynamics And Interaction With Vp16 Activation Domain, 20 Structures
		protein W03F9.5 [imported] - Caenorhabditis elegans
		transcription initiation factor B [Methanococcus maripaludis S2]
		Chain A, Tfiib (Human Core Domain)TBP (A.THALIANA)TATA ELEMENT Ternary Complex
		mutant TFIIB3 [Arabidopsis thaliana]
		archaeal transcription factor B [Methanothermococcus thermolithotrophicus]
		transcription initiation factor IIB (TFIIB)-like protein [Arabidopsis thaliana]
		transcription initiation factor IIB related protein [Thermoplasma acidophilum DSM 1728]
		Putative transcription initiation factor IIB [Oryza sativa (japonica cultivar-group)]
		transcription initiation factor IIB [Picrophilus torridus DSM 9790]
		Transcription initiation factor IIB [Methanopyrus kandleri AV19]
		hypothetical protein NEQ276 [Nanoarchaeum equitans Kin4-M]
		Transcription initiation factor IIB [Methanopyrus kandleri AV19]
		COG1405: Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB [Ferroplasma acidarmanus]
		Transcription initiation factor IIB [Thermoplasma volcanium GSS1]
		hypothetical transcription initiation factor IIB [Sulfolobus tokodaii str. 7]
		transcription initiation factor IIB [Thermococcus kodakaraensis KOD1]
		transcription initiation factor IIB [Haloarcula marismortui ATCC 43049]
		transcription initiation factor IIB [uncultured archaeon GZfos34G5]
		archaeal transcription factor B [Methanosarcina acetivorans C2A]
		COG1405: Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB [Methanosarcina barkeri str. fusaro]
		Transcription initiation factor IIB [Methanosarcina mazei Go1]
		transcription initiation factor TFIIB Sua7p; ZnR+2cyclins [Cryptosporidium parvum]
		transcription initiation factor IIB [Haloarcula marismortui ATCC 43049]
		transcription initiation factor IIB [Haloarcula marismortui ATCC 43049]
		COG1405: Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB [Methanococcoides burtonii DSM 6242]
		TfbB [Halobacterium sp. NRC-1]
		transcription initiation factor IIB [Haloarcula marismortui ATCC 43049]
		Transcription initiation factor IIB (TFIIB) homolog (TFB-1) [Sulfolobus solfataricus P2]
		transcription factor TFIIB homolog TFB [imported] - Sulfolobus shibatae
		TfbC [Halobacterium sp. NRC-1]
		transcription factor B [Haloferax volcanii]
		TfbF [Halobacterium sp. NRC-1]
		TfbD [Halobacterium sp. NRC-1]
		transcription initiation factor IIB (TFIIB) [Methanocaldococcus jannaschii DSM 2661]
		hypothetical transcription initiation factor IIB chain b [Pyrococcus furiosus DSM 3638]
		TfbA [Halobacterium sp. NRC-1]
		transcription initiation factor IIB [Haloarcula marismortui ATCC 43049]
		Transcription initiation factor IIB (TFIIB) homolog (TFB-2) [Sulfolobus solfataricus P2]
		transcription factor IIB [Pyrococcus woesei]
		transcription initiation factor IIB [uncultured archaeon GZfos1C11]
		TfbE [Halobacterium sp. NRC-1]
		transcription initiation factor IIB [Haloarcula marismortui ATCC 43049]
		archaeal transcription factor B [Sulfolobus acidocaldarius]
		transcription factor IIB, TFIIB=sua7-1 variant [Saccharomyces cerevisiae, Peptide Partial Mutant, 68 aa]
		TFIIB6 [Arabidopsis thaliana]
		transcription factor IIB, TFIIB=sua7-3 variant [Saccharomyces cerevisiae, Peptide Partial Mutant, 68 aa]
		transcription initiation factor IIB [Haloarcula marismortui ATCC 43049]
		hypothetical transcription initiation factor IIB [Sulfolobus tokodaii str. 7]
		TFIIB-related protein [Zea mays]
		transcription initiation factor TFIIB, putative [Plasmodium berghei]
		putative transcription initiation factor TFIIB [uncultured crenarchaeote]
		TFIIB-related protein [Spinacia oleracea]
		transcription initiation factor IIB 5 [Haloarcula marismortui ATCC 43049]
		transcription initiation factor TFIIB [Cryptosporidium hominis]
		transcription initiation factor IIB (TFIIB) [Pyrobaculum aerophilum str. IM2]
		BAC19.3 [Lycopersicon esculentum]
		N-Terminal Domain Of Tfiib, Nmr
		Chain A, Rdc-Derived Models Of The Zinc Ribbon Domain Of Human General Transcription Factor Tfiib (Zinc Free Structures)
		Chain A, Solution Structure Of Human Tfiib N-Terminal Domain
		unnamed protein product [Candida glabrata CBS138]
		TFIIB5/pBrp [Arabidopsis thaliana]
		Chain B, Tata-Binding ProteinTRANSCRIPTION FACTOR (II)BBRE+TATA- Box Complex From Pyrococcus Woesei
		transcription initiation factor TFIIB, putative [Plasmodium falciparum 3D7]
		Chain B, Tata-Binding ProteinTRANSCRIPTION FACTOR (II)BTATA-Box Complex From Pyrococcus Woesei
		transcription initiation factor iib [Plasmodium yoelii yoelii]
		TF3B_KLULA [Kluyveromyces lactis NRRL Y-1140]
		transcription initiation factor IIIB chain BRF - yeast (Kluyveromyces marxianus var. lactis)
		TFIIB related subunit of TFIIIB (BRF1) [Kluyveromyces lactis]
		transcription factor B [Pyrodictium occultum]
		transcription initiation factor IIB [Pyrococcus horikoshii OT3]
		likely transcription factor TFIIB fragment [Candida albicans SC5314]
		unnamed protein product [Tetraodon nigroviridis]

gb|AAK39738.1| transcription initiation factor IIB [Guillardia theta]
ref|NP_113167.1| transcription initiation factor IIB [Guillardia theta]
pir||G90130 transcription initiation factor IIB tfIIB [imported] - Guillardia theta nucleomorph
(325 aa)

Score: 210 bits (534), Expect: 6.87733e-53
Length: 316, Idn/Pos/Gap = 112/186/13 (35%/58%/4%)

Query:  12 DVCGECGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSIN  71
           + C  CGS   +ED K GD++C  CG +    +ID G EWR F +D+ + +P R+G   N
Sbjct:   2 NTCINCGSKRFLEDYKQGDIICKNCGFIIESHIIDFGSEWRIFSDDNRSNNPVRIGLPEN  61

Query:  72 PLLDSGLATSISQGPAGANALNERLARAQSRNVLDANDRYVTECYNRISYLCERSGLPQL 131
           PLL +  +T IS+G  G+N +NE+L +AQ++N    +++Y+   ++ IS+        +L
Sbjct:  62 PLLGNSSSTLISKGLKGSNKINEKLLKAQNQNDNCKSEKYLASVFSIISFFLTNGSFSKL 121

Query: 132 VKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRTFNEISV 191
           +K++  EL + YYD+LTL ++G R +   R+ +T SII+A++FI C+NE  PR+F EIS 
Sbjct: 122 IKEKVQELFKNYYDYLTLKSNGSRIKTTLRKKDTFSIIAASIFIICKNESIPRSFKEISE 181

Query: 192 IVSVAKSRVAAYVKAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPNIVRSLVNQVARAA 251
           +  V K  +   V+ ME ++ E  KIS+ R +D+F+SRFCS L + +    +  Q+A   
Sbjct: 182 LTKVKKKDIGNRVRIMEKAL-EGIKISKKRDSDNFISRFCSKLGLSSTSSKIAEQIANFI 240

Query: 252 AEKDGIHGRTLVSIAAGAIYFVLLLWRETCPQSIPATLRVSDEALVNRIAEVSGITEGVV 311
            +K+G++GR  +S+AA +IY V           IP    +S+   + +I E +G++E  +
Sbjct: 241 KDKEGMYGRNYISVAAASIYVV---------SQIP---NLSNNCNLKKIIEATGVSEITL 288

Query: 312 KTVASRIRQYRDRGLL 327
           ++    +  YR   LL
Sbjct: 289 RSAYKAMYPYRKEILL 304

gb|EAA05904.2| ENSANGP00000020059 [Anopheles gambiae str. PEST]
ref|XP_310128.2| ENSANGP00000020059 [Anopheles gambiae str. PEST]
(422 aa)

Score: 177 bits (449), Expect: 4.94007e-43
Length: 253, Idn/Pos/Gap = 96/147/19 (37%/58%/7%)

Query:  22 LVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSINPLLDSG-LAT  80
           L+ED + GD++C++CG+V  + +ID+G EWRTF N+ +  DP+RVGG  NPLL  G L+T
Sbjct: 129 LIEDYRAGDMICSECGLVVGDRVIDVGSEWRTFSNEKAGVDPSRVGGPENPLLSGGDLST 188

Query:  81 SI--SQGPAGANALNERLARAQSRNVLDANDRYVTECYNRISYLCERSGLPQLVKDRACE 138
            I    GPA  +A     A+ Q+R  + ++DR +   +  IS + +R  LP+ + DRA  
Sbjct: 189 MIGPGTGPASFDAFGT--AKYQNRRTMSSSDRALIAAFKEISTMADRINLPKTITDRANN 246

Query: 139 LLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRTFNEISVIVSVAKS 198
           L +  +D   L      A+A           SA L+IACR EG PRTF EI  +  ++K 
Sbjct: 247 LFKQVHDGKNLKGRSNDAKA-----------SACLYIACRQEGVPRTFKEICAVSKISKK 295

Query: 199 RVAAYVKAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPNIVRSLVNQVARAAAEKDGIH 258
            +    +  ++++   A    + TT DF+SRFC+ L++PN+V+     +AR A E D + 
Sbjct: 296 EIG---RCFKLTLKALATSVDLITTADFMSRFCANLDLPNVVQRAATHIARKAVEMDIVP 352

Query: 259 GRTLVSIAAGAIY 271
           GR+ +S+AA AIY
Sbjct: 353 GRSPISVAAAAIY 365

gb|EAL61980.1| transcription initiation factor IIB [Dictyostelium discoideum]
(325 aa)

Score: 172 bits (435), Expect: 2.02421e-41
Length: 312, Idn/Pos/Gap = 106/163/33 (33%/52%/10%)

Query:  21 DLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDS-AYDPNRVGGSINPLL-DSGL  78
           D++ED   GDL+C  CGVV  + ++D   EWRTF N +S   DPNRVGG INPLL DS L
Sbjct:  32 DIIEDYAKGDLICRGCGVVVGDRIVDEHSEWRTFSNSESTGADPNRVGGPINPLLRDSAL  91

Query:  79 ATSISQGPAGANALNERLARAQSRNVLDANDRYVTECYNRISYLCERSGLPQLVKDRACE 138
           +T++ +G   +      L R Q+++ L   DR +   +  I  + +   LPQ V+DRA E
Sbjct:  92 STTVGKGSKDSGT----LTRLQNKSALGTGDRNLLAAFKEIGRMADHMNLPQTVQDRANE 147

Query: 139 LLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRTFNEISVIVSVAKS 198
           L R   D  +     V             +++AAL+IACR E   RTF EI+ + +V K 
Sbjct: 148 LFRFMDDKKSTKGRSVDG-----------MVAAALYIACRQEHLSRTFKEIAALTNVPKK 196

Query: 199 RVAAYVKAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPNIVRSLVNQVARAAAEKDGIH 258
            ++   K M+ +      +  I +++DF SRFCS L++PN V+     V++ A +   + 
Sbjct: 197 EISRCYKIMKETFASVLNLQTI-SSEDFTSRFCSTLKLPNDVKKGAEHVSKMAMDMGIVA 255

Query: 259 GRTLVSIAAGAIYFVLLLWRETCPQSIPATLRVSDEALVNRIAEVSGITEGVVKTVASRI 318
           G++ +S+ A +IY V  L  E   Q               +IA+VSG++E  ++     +
Sbjct: 256 GKSPISVTAASIYMVSQLSPEKRTQ--------------KQIADVSGVSEVTIRNAYKDL 301

Query: 319 RQYRDRGLLPPD 330
              RD+ L+P D
Sbjct: 302 YAKRDQ-LIPSD 312

gb|AAT84346.1| general transcription factor II B [Oreochromis mossambicus]
(318 aa)

Score: 170 bits (430), Expect: 6.50977e-41
Length: 338, Idn/Pos/Gap = 112/176/45 (33%/52%/13%)

Query:  11 PDVCGECGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSI  70
           PD C       LVED + GD++C +CG+V  + +ID+G EWRTF N+ +  DP+RVG + 
Sbjct:  21 PDAC-------LVEDYRAGDMICPECGLVVGDRVIDVGSEWRTFSNEKALKDPSRVGDAQ  73

Query:  71 NPLLDSG-LATSISQGPAGANALNERLARAQSRNVLDANDRYVTECYNRISYLCERSGLP 129
           NPLL+ G L T IS+G   A+      ++ Q+R  + ++DR +   +  IS + +R  LP
Sbjct:  74 NPLLNGGDLTTMISKGTGAASFDEFGNSKYQNRRTMSSSDRAMLNAFKEISTMADRINLP 133

Query: 130 QLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRTFNEI 189
           + + DR   L +  Y+  +L     + RA        +I SA L+IACR EG PRTF EI
Sbjct: 134 RNIVDRTNNLFKQVYEQKSL-----KGRA------NDAIASACLYIACRQEGVPRTFKEI 182

Query: 190 SVIVSVAKSRVAA----YVKAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPNIVRSLVN 245
             +  ++K  +       +KA+E S+        + TT DF+SRFCS L +P  V+    
Sbjct: 183 CAVSRISKKEIGRCFKLILKALETSVD-------LITTGDFMSRFCSNLGLPKQVQMAAT 235

Query: 246 QVARAAAEKDGIHGRTLVSIAAGAIYFVLLLWRETCPQSIPATLRVSDEALVNRIAEVSG 305
            +AR A E D + GR+ +S+AA AIY               A+   +++     I +++G
Sbjct: 236 FIARKAVELDLVPGRSPISVAAAAIYM--------------ASQASAEKKTQKEIGDIAG 281

Query: 306 ITEGVVKTVASRIRQYRDRGLLPPDWVRRFPSRLEPEL 343
           + +  ++  + R+   R   L PPD+    P    P+L
Sbjct: 282 VADVTIRQ-SYRLIYPRAAELFPPDFKFDTPVDKLPQL 318

ref|NP_476888.1| CG5193-PA [Drosophila melanogaster]
gb|AAT94498.1| LD24035p [Drosophila melanogaster]
gb|AAF52951.1| CG5193-PA [Drosophila melanogaster]
gb|AAA68626.1| transcription factor IIB [Drosophila melanogaster]
sp|P29052|TF2B_DROME Transcription initiation factor IIB (General transcription factor TFIIB)
gb|AAA79093.1| transcription factor IIB [Drosophila melanogaster]
gb|AAR99117.1| RE29729p [Drosophila melanogaster]
gb|AAA28930.1| transcription factor IIB
gb|AAA28929.1| RNA polymerase II transcription factor
(315 aa)

Score: 169 bits (428), Expect: 1.26899e-40
Length: 255, Idn/Pos/Gap = 95/144/23 (37%/56%/9%)

Query:  22 LVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSINPLLDSG-LAT  80
           L+ED + GD++C++CG+V  + +ID+G EWRTF N+ S  DP+RVGG  NPLL  G L+T
Sbjct:  22 LIEDYRAGDMICSECGLVVGDRVIDVGSEWRTFSNEKSGVDPSRVGGPENPLLSGGDLST  81

Query:  81 SISQGPAGANALNERLARAQSRNVLDANDRYVTECYNRISYLCERSGLPQLVKDRACELL 140
            I  G   A+       + Q+R  + ++DR +   +  IS + +R  LP+ + DRA  L 
Sbjct:  82 IIGPGTGSASFDAFGAPKYQNRRTMSSSDRSLISAFKEISSMADRINLPKTIVDRANNLF 141

Query: 141 RLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRTFNEISVIVSVAKSRV 200
           +  +D   L      A+A           SA L+IACR EG PRTF EI  +  ++K  +
Sbjct: 142 KQVHDGKNLKGRSNDAKA-----------SACLYIACRQEGVPRTFKEICAVSKISKKEI 190

Query: 201 AA----YVKAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPNIVRSLVNQVARAAAEKDG 256
                  +KA+E S+        + TT DF+ RFC+ L++PN+V+     +A+ A E D 
Sbjct: 191 GRCFKLTLKALETSVD-------LITTADFMCRFCANLDLPNMVQRAATHIAKKAVEMDI 243

Query: 257 IHGRTLVSIAAGAIY 271
           + GR+ +S+AA AIY
Sbjct: 244 VPGRSPISVAAAAIY 258

ref|XP_395432.1| similar to Transcription initiation factor IIB (General transcription factor TFIIB) [Apis mellifera]
(315 aa)

Score: 168 bits (426), Expect: 2.16456e-40
Length: 255, Idn/Pos/Gap = 96/147/23 (37%/57%/9%)

Query:  22 LVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSINPLLD-SGLAT  80
           L+ED + GD +C++CG+V  + +ID+G EWRTF N+ +  DP+RVGG  NPLL+ S L+T
Sbjct:  22 LIEDYRAGDQICSECGLVVGDRVIDVGSEWRTFSNEKAGVDPSRVGGPENPLLNGSDLST  81

Query:  81 SISQGPAGANALNERLARAQSRNVLDANDRYVTECYNRISYLCERSGLPQLVKDRACELL 140
            I  G   A+      ++ Q+R  + ++DR +   +  I+ + +R  LP+ + DRA  L 
Sbjct:  82 MIGPGTGAASFDAFGASKYQNRRTMSSSDRALINAFREINGMADRINLPKTIVDRANNLF 141

Query: 141 RLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRTFNEISVIVSVAKSRV 200
           +  +D        ++ RA        +I SA L+IACR EG PRTF EI  +  ++K  +
Sbjct: 142 KQVHD-----GKNLKGRA------NDAIASACLYIACRQEGVPRTFKEICAVSKISKKEI 190

Query: 201 AA----YVKAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPNIVRSLVNQVARAAAEKDG 256
                  +KA+E S+        + TT DF+SRFCS L +PN+V+     +AR A E D 
Sbjct: 191 GRCFKLILKALETSVD-------LITTGDFMSRFCSNLGLPNMVQRAATHIARKAVEIDI 243

Query: 257 IHGRTLVSIAAGAIY 271
           + GR+ +S+AA AIY
Sbjct: 244 VPGRSPISVAAAAIY 258

ref|XP_513540.1| PREDICTED: similar to kynurenine aminotransferase III [Pan troglodytes]
(1488 aa)

Score: 167 bits (424), Expect: 3.34041e-40
Length: 327, Idn/Pos/Gap = 108/171/38 (33%/52%/11%)

Query:   22 LVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSINPLLDSG-LAT   80
            LVED + GD++C +CG+V  + +ID+G EWRTF ND +  DP+RVG S NPLL  G L+T
Sbjct: 1195 LVEDYRAGDMICPECGLVVGDRVIDVGSEWRTFSNDKATKDPSRVGDSQNPLLSDGDLST 1254

Query:   81 SISQGPAGANALNERLARAQSRNVLDANDRYVTECYNRISYLCERSGLPQLVKDRACELL  140
             I +G   A+      ++ Q+R  + ++DR +   +  I+ + +R  LP+ + DR   L 
Sbjct: 1255 MIGKGTGAASFDEFGNSKYQNRRTMSSSDRAMMNAFKEITTMADRINLPRNIVDRTNNLF 1314

Query:  141 RLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRTFNEISVIVSVAKSRV  200
            +  Y+  +L     + RA        +I SA L+IACR EG PRTF EI  +  ++K  +
Sbjct: 1315 KQVYEQKSL-----KGRA------NDAIASACLYIACRQEGVPRTFKEICAVSRISKKEI 1363

Query:  201 AA----YVKAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPNIVRSLVNQVARAAAEKDG  256
                   +KA+E S+        + TT DF+SRFCS L +P  V+     +AR A E D 
Sbjct: 1364 GRCFKLILKALETSVD-------LITTGDFMSRFCSNLCLPKQVQMAATHIARKAVELDL 1416

Query:  257 IHGRTLVSIAAGAIYFVLLLWRETCPQSIPATLRVSDEALVNRIAEVSGITEGVVKTVAS  316
            + GR+ +S+AA AIY               A+   +++     I +++G+ +  ++  + 
Sbjct: 1417 VPGRSPISVAAAAIYM--------------ASQASAEKRTQKEIGDIAGVADVTIRQ-SY 1461

Query:  317 RIRQYRDRGLLPPDWVRRFPSRLEPEL  343
            R+   R   L P D+    P    P+L
Sbjct: 1462 RLIYPRAPDLFPTDFKFDTPVDKLPQL 1488

gb|AAH55569.1| General transcription factor IIB [Danio rerio]
ref|NP_955991.1| general transcription factor IIB [Danio rerio]
(316 aa)

Score: 167 bits (423), Expect: 5.11217e-40
Length: 327, Idn/Pos/Gap = 107/174/38 (32%/53%/11%)

Query:  22 LVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSINPLLDSG-LAT  80
           LVED + GD++C +CG+V  + +ID+G EWRTF N+ +  DP+RVG + NPLL+ G L T
Sbjct:  23 LVEDYRAGDMICPECGLVVRDRVIDVGSEWRTFSNEKATKDPSRVGDAQNPLLNGGDLTT  82

Query:  81 SISQGPAGANALNERLARAQSRNVLDANDRYVTECYNRISYLCERSGLPQLVKDRACELL 140
            IS+G   A+      ++ Q+R  + ++DR +   +  I+ + +R  LP+ + DR   L 
Sbjct:  83 MISKGTGAASFDEFGNSKYQNRRTMSSSDRAMLNAFKEITTMADRINLPRNIIDRTNNLF 142

Query: 141 RLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRTFNEISVIVSVAKSRV 200
           +  Y+  +L         + R ++  +I SA L+IACR EG PRTF EI  +  ++K  +
Sbjct: 143 KQVYEQKSL---------KGRSND--AIASACLYIACRQEGVPRTFKEICAVSRISKKEI 191

Query: 201 AA----YVKAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPNIVRSLVNQVARAAAEKDG 256
                  +KA+E S+        + TT DF+SRFCS L +P  V+     +AR A E D 
Sbjct: 192 GRCFKLILKALETSVD-------LITTGDFMSRFCSNLGLPKQVQMAATYIARKAVELDL 244

Query: 257 IHGRTLVSIAAGAIYFVLLLWRETCPQSIPATLRVSDEALVNRIAEVSGITEGVVKTVAS 316
           + GR+ +S+AA AIY               A+   +++     I +++G+ +  ++  + 
Sbjct: 245 VPGRSPISVAAAAIYM--------------ASQASAEKKTQKEIGDIAGVADVTIRQ-SY 289

Query: 317 RIRQYRDRGLLPPDWVRRFPSRLEPEL 343
           R+   R   L PPD+    P    P+L
Sbjct: 290 RLIYPRAADLFPPDFKFDTPVDKLPQL 316

emb|CAF96369.1| unnamed protein product [Tetraodon nigroviridis]
(344 aa)

Score: 167 bits (422), Expect: 6.24558e-40
Length: 323, Idn/Pos/Gap = 106/170/38 (32%/52%/11%)

Query:  14 CGECGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSINPL  73
           C     + LVED + GD++C +CG+V  + +ID+G EWRTF N+ +  DP+RVG + NPL
Sbjct:  43 CPNHPDSTLVEDYRAGDMICPECGLVVGDRVIDVGSEWRTFSNEKALKDPSRVGDAQNPL 102

Query:  74 LDSG-LATSISQGPAGANALNERLARAQSRNVLDANDRYVTECYNRISYLCERSGLPQLV 132
           L+ G L T I +G   A+      ++ Q+R  + ++DR +   +  IS + +R  LP+ +
Sbjct: 103 LNGGDLTTMIGKGTGAASFDEFGNSKYQNRRTMSSSDRAMLNAFKEISTMADRINLPRNI 162

Query: 133 KDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRTFNEISVI 192
            DR   L +  Y+  +L     + RA        +I SA L+IACR EG PRTF EI  +
Sbjct: 163 IDRTNNLFKQVYEQKSL-----KGRA------NDAIASACLYIACRQEGVPRTFKEICAV 211

Query: 193 VSVAKSRVAA----YVKAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPNIVRSLVNQVA 248
             ++K  +       +KA+E S+        + TT DF+SRFCS L +P  V+     +A
Sbjct: 212 SRISKKEIGRCFKLILKALETSVD-------LITTGDFMSRFCSNLGLPKQVQMAATFIA 264

Query: 249 RAAAEKDGIHGRTLVSIAAGAIYFVLLLWRETCPQSIPATLRVSDEALVNRIAEVSGITE 308
           R A E D + GR+ +S+AA AIY               A+   +++     I +++G+ +
Sbjct: 265 RKAVELDLVPGRSPISVAAAAIYM--------------ASQASAEKKTQKEIGDIAGVAD 310

Query: 309 GVVKTVASRIRQYRDRGLLPPDW 331
             ++  + R+   R   L PPD+
Sbjct: 311 VTIRQ-SYRLIYPRAAELFPPDF 332

ref|XP_537085.1| PREDICTED: similar to Transcription initiation factor IIB (General transcription factor TFIIB) (S300-II) [Canis familiaris]
emb|CAA41958.1| IIB protein [Homo sapiens]
emb|CAH92024.1| hypothetical protein [Pongo pygmaeus]
emb|CAI41341.1| OTTHUMP00000058838 [Homo sapiens]
gb|AAH21000.1| General transcription factor IIB [Homo sapiens]
gb|AAH20597.1| General transcription factor IIB [Homo sapiens]
sp|Q00403|TF2B_HUMAN Transcription initiation factor IIB (General transcription factor TFIIB) (S300-II)
ref|NP_001505.1| general transcription factor IIB [Homo sapiens]
gb|AAA61149.1| transcription factor
prf||1715332A transcription initiation factor IIB
(316 aa)

Score: 166 bits (421), Expect: 8.43382e-40
Length: 327, Idn/Pos/Gap = 108/171/38 (33%/52%/11%)

Query:  22 LVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSINPLLDSG-LAT  80
           LVED + GD++C +CG+V  + +ID+G EWRTF ND +  DP+RVG S NPLL  G L+T
Sbjct:  23 LVEDYRAGDMICPECGLVVGDRVIDVGSEWRTFSNDKATKDPSRVGDSQNPLLSDGDLST  82

Query:  81 SISQGPAGANALNERLARAQSRNVLDANDRYVTECYNRISYLCERSGLPQLVKDRACELL 140
            I +G   A+      ++ Q+R  + ++DR +   +  I+ + +R  LP+ + DR   L 
Sbjct:  83 MIGKGTGAASFDEFGNSKYQNRRTMSSSDRAMMNAFKEITTMADRINLPRNIVDRTNNLF 142

Query: 141 RLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRTFNEISVIVSVAKSRV 200
           +  Y+  +L     + RA        +I SA L+IACR EG PRTF EI  +  ++K  +
Sbjct: 143 KQVYEQKSL-----KGRA------NDAIASACLYIACRQEGVPRTFKEICAVSRISKKEI 191

Query: 201 AA----YVKAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPNIVRSLVNQVARAAAEKDG 256
                  +KA+E S+        + TT DF+SRFCS L +P  V+     +AR A E D 
Sbjct: 192 GRCFKLILKALETSVD-------LITTGDFMSRFCSNLCLPKQVQMAATHIARKAVELDL 244

Query: 257 IHGRTLVSIAAGAIYFVLLLWRETCPQSIPATLRVSDEALVNRIAEVSGITEGVVKTVAS 316
           + GR+ +S+AA AIY               A+   +++     I +++G+ +  ++  + 
Sbjct: 245 VPGRSPISVAAAAIYM--------------ASQASAEKRTQKEIGDIAGVADVTIRQ-SY 289

Query: 317 RIRQYRDRGLLPPDWVRRFPSRLEPEL 343
           R+   R   L P D+    P    P+L
Sbjct: 290 RLIYPRAPDLFPTDFKFDTPVDKLPQL 316

gb|AAB23144.1| S300-II; TFIIB [Homo sapiens]
(311 aa)

Score: 166 bits (421), Expect: 8.64759e-40
Length: 327, Idn/Pos/Gap = 108/171/38 (33%/52%/11%)

Query:  22 LVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSINPLLDSG-LAT  80
           LVED + GD++C +CG+V  + +ID+G EWRTF ND +  DP+RVG S NPLL  G L+T
Sbjct:  18 LVEDYRAGDMICPECGLVVGDRVIDVGSEWRTFSNDKATKDPSRVGDSQNPLLSDGDLST  77

Query:  81 SISQGPAGANALNERLARAQSRNVLDANDRYVTECYNRISYLCERSGLPQLVKDRACELL 140
            I +G   A+      ++ Q+R  + ++DR +   +  I+ + +R  LP+ + DR   L 
Sbjct:  78 MIGKGTGAASFDEFGNSKYQNRRTMSSSDRAMMNAFKEITTMADRINLPRNIVDRTNNLF 137

Query: 141 RLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRTFNEISVIVSVAKSRV 200
           +  Y+  +L     + RA        +I SA L+IACR EG PRTF EI  +  ++K  +
Sbjct: 138 KQVYEQKSL-----KGRA------NDAIASACLYIACRQEGVPRTFKEICAVSRISKKEI 186

Query: 201 AA----YVKAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPNIVRSLVNQVARAAAEKDG 256
                  +KA+E S+        + TT DF+SRFCS L +P  V+     +AR A E D 
Sbjct: 187 GRCFKLILKALETSVD-------LITTGDFMSRFCSNLCLPKQVQMAATHIARKAVELDL 239

Query: 257 IHGRTLVSIAAGAIYFVLLLWRETCPQSIPATLRVSDEALVNRIAEVSGITEGVVKTVAS 316
           + GR+ +S+AA AIY               A+   +++     I +++G+ +  ++  + 
Sbjct: 240 VPGRSPISVAAAAIYM--------------ASQASAEKRTQKEIGDIAGVADVTIRQ-SY 284

Query: 317 RIRQYRDRGLLPPDWVRRFPSRLEPEL 343
           R+   R   L P D+    P    P+L
Sbjct: 285 RLIYPRAPDLFPTDFKFDTPVDKLPQL 311

ref|NP_112303.1| general transcription factor IIB [Rattus norvegicus]
ref|NP_663521.1| general transcription factor IIB [Mus musculus]
gb|AAH85345.1| General transcription factor IIB [Rattus norvegicus]
gb|AAH16637.1| General transcription factor IIB [Mus musculus]
emb|CAA46766.1| alpha initiation factor [Rattus norvegicus]
sp|P62915|TF2B_MOUSE Transcription initiation factor IIB (General transcription factor TFIIB) (RNA polymerase II alpha initiation factor)
sp|P62916|TF2B_RAT Transcription initiation factor IIB (General transcription factor TFIIB) (RNA polymerase II alpha initiation factor)
(316 aa)

Score: 166 bits (420), Expect: 9.47884e-40
Length: 327, Idn/Pos/Gap = 108/171/38 (33%/52%/11%)

Query:  22 LVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSINPLLDSG-LAT  80
           LVED + GD++C +CG+V  + +ID+G EWRTF ND +  DP+RVG S NPLL  G L+T
Sbjct:  23 LVEDYRAGDMICPECGLVVGDRVIDVGSEWRTFSNDKATKDPSRVGDSQNPLLSDGDLST  82

Query:  81 SISQGPAGANALNERLARAQSRNVLDANDRYVTECYNRISYLCERSGLPQLVKDRACELL 140
            I +G   A+      ++ Q+R  + ++DR +   +  I+ + +R  LP+ + DR   L 
Sbjct:  83 MIGKGTGAASFDEFGNSKYQNRRTMSSSDRAMMNAFKEITTMADRINLPRNIVDRTNNLF 142

Query: 141 RLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRTFNEISVIVSVAKSRV 200
           +  Y+  +L     + RA        +I SA L+IACR EG PRTF EI  +  ++K  +
Sbjct: 143 KQVYEQKSL-----KGRA------NDAIASACLYIACRQEGVPRTFKEICAVSRISKKEI 191

Query: 201 AA----YVKAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPNIVRSLVNQVARAAAEKDG 256
                  +KA+E S+        + TT DF+SRFCS L +P  V+     +AR A E D 
Sbjct: 192 GRCFKLILKALETSVD-------LITTGDFMSRFCSNLCLPKQVQMAATHIARKAVELDL 244

Query: 257 IHGRTLVSIAAGAIYFVLLLWRETCPQSIPATLRVSDEALVNRIAEVSGITEGVVKTVAS 316
           + GR+ +S+AA AIY               A+   +++     I +++G+ +  ++  + 
Sbjct: 245 VPGRSPISVAAAAIYM--------------ASQASAEKRTQKEIGDIAGVADVTIRQ-SY 289

Query: 317 RIRQYRDRGLLPPDWVRRFPSRLEPEL 343
           R+   R   L P D+    P    P+L
Sbjct: 290 RLIYPRAPDLFPSDFKFDTPVDKLPQL 316

gb|EAL34233.1| GA18726-PA [Drosophila pseudoobscura]
(310 aa)

Score: 162 bits (411), Expect: 1.19769e-38
Length: 255, Idn/Pos/Gap = 92/140/23 (36%/54%/9%)

Query:  22 LVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSINPLL-DSGLAT  80
           L+ED + GD++C++CG+V  + +ID+G EWRTF N+ S  DP+RVGG  NPLL       
Sbjct:  17 LIEDYRAGDMICSECGLVVGDRVIDVGSEWRTFSNEKSGVDPSRVGGPENPLLXXXXXXX  76

Query:  81 SISQGPAGANALNERLARAQSRNVLDANDRYVTECYNRISYLCERSGLPQLVKDRACELL 140
            I  G   A+       + Q+R  + ++DR +   +  IS + +R  LP+ + DRA  L 
Sbjct:  77 XIGPGTGSASFDAFGAPKYQNRRTMSSSDRSLISAFKEISSMADRINLPKTIVDRANNLF 136

Query: 141 RLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRTFNEISVIVSVAKSRV 200
           +  +D   L      A+A           SA L+IACR EG PRTF EI  +  ++K  +
Sbjct: 137 KQVHDGKNLKGRSNDAKA-----------SACLYIACRQEGVPRTFKEICAVSKISKKEI 185

Query: 201 AA----YVKAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPNIVRSLVNQVARAAAEKDG 256
                  +KA+E S+        + TT DF+ RFC+ L++PN+V+     +A+ A E D 
Sbjct: 186 GRCFKLTLKALETSVD-------LITTADFMCRFCANLDLPNMVQRAATHIAKKAVEMDI 238

Query: 257 IHGRTLVSIAAGAIY 271
           + GR+ +S+AA AIY
Sbjct: 239 VPGRSPISVAAAAIY 253

ref|XP_613351.1| PREDICTED: similar to Transcription initiation factor IIB (General transcription factor TFIIB) (S300-II) [Bos taurus]
(316 aa)

Score: 162 bits (411), Expect: 1.31281e-38
Length: 327, Idn/Pos/Gap = 107/169/38 (32%/51%/11%)

Query:  22 LVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSINPLLDSG-LAT  80
           LVED +  D++C +CG+V  + +ID+G EWRTF ND +  DP+RVG S NPLL  G L+T
Sbjct:  23 LVEDYRAADMICPECGLVVGDRVIDVGSEWRTFSNDKATKDPSRVGDSQNPLLSDGDLST  82

Query:  81 SISQGPAGANALNERLARAQSRNVLDANDRYVTECYNRISYLCERSGLPQLVKDRACELL 140
            I +G   A+      +  Q+R  + ++DR +   +  I+ + +R  LP+ + DR   L 
Sbjct:  83 MIGKGTGAASFDEFGNSNYQNRRTMSSSDRAMMNAFKEITTMADRINLPRNIVDRTNNLF 142

Query: 141 RLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRTFNEISVIVSVAKSRV 200
           +  Y+  +L     + RA        +I SA L+IACR EG PRTF EI  +  ++K  +
Sbjct: 143 KQVYEQKSL-----KGRA------NDAIASACLYIACRQEGVPRTFKEICAVSRISKKEI 191

Query: 201 AA----YVKAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPNIVRSLVNQVARAAAEKDG 256
                  +KA+E S+        + TT DF+SRFCS L +P  V+     +AR A E D 
Sbjct: 192 GRCFKLILKALETSVD-------LITTGDFMSRFCSNLCLPKQVQMAATHIARKAVELDL 244

Query: 257 IHGRTLVSIAAGAIYFVLLLWRETCPQSIPATLRVSDEALVNRIAEVSGITEGVVKTVAS 316
           + GR+ +S+AA AIY               A+   +++     I +++G+ +  ++  + 
Sbjct: 245 VPGRSPISVAAAAIYM--------------ASQASAEKRTQKEIGDIAGVADVTIRQ-SY 289

Query: 317 RIRQYRDRGLLPPDWVRRFPSRLEPEL 343
           R+   R   L P D+    P    P+L
Sbjct: 290 RLIYPRAPDLFPTDFKFDTPVDKLPQL 316

ref|NP_001016277.1| hypothetical protein LOC549031 [Xenopus tropicalis]
(316 aa)

Score: 162 bits (409), Expect: 1.81771e-38
Length: 327, Idn/Pos/Gap = 105/171/38 (32%/52%/11%)

Query:  22 LVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSINPLLDSG-LAT  80
           LVED + GD++C++CG+V  + +ID+G EWRTF ND +A DP+RVG + NPLL  G L T
Sbjct:  23 LVEDYRAGDMICSECGLVVGDRVIDVGSEWRTFSNDKAAKDPSRVGDAQNPLLSGGDLTT  82

Query:  81 SISQGPAGANALNERLARAQSRNVLDANDRYVTECYNRISYLCERSGLPQLVKDRACELL 140
            I +G   A+       + Q+R  + ++DR +   +  I+ + +R  LP+ + DR   L 
Sbjct:  83 MIGKGTGAASFDEFGNNKYQNRRTMSSSDRAMMNAFKEITNMADRINLPRNIVDRTNNLF 142

Query: 141 RLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRTFNEISVIVSVAKSRV 200
           +  Y+  +L         + R ++  +I SA L+IACR EG PRTF EI  +  ++K  +
Sbjct: 143 KQVYEQKSL---------KGRSND--AIASACLYIACRQEGVPRTFKEICAVSRISKKEI 191

Query: 201 AA----YVKAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPNIVRSLVNQVARAAAEKDG 256
                  +KA+E ++        + TT DF+SRFCS L +   V+     +AR A E D 
Sbjct: 192 GRCFKLILKALETNVD-------LITTGDFMSRFCSNLGLTKQVQMAATHIARKAVELDL 244

Query: 257 IHGRTLVSIAAGAIYFVLLLWRETCPQSIPATLRVSDEALVNRIAEVSGITEGVVKTVAS 316
           + GR+ +S+AA AIY               A+   +++     I +++G+ +  ++  + 
Sbjct: 245 VPGRSPISVAAAAIYM--------------ASQASAEKRTQKEIGDIAGVADVTIRQ-SY 289

Query: 317 RIRQYRDRGLLPPDWVRRFPSRLEPEL 343
           R+   R   L P D+    P    P+L
Sbjct: 290 RLIYPRAPDLFPADFKFDTPVDKLPQL 316

emb|CAA44668.1| TFIIB [Xenopus laevis]
gb|AAH77495.1| Unknown (protein for MGC:82605) [Xenopus laevis]
sp|P29054|TF2B_XENLA Transcription initiation factor IIB (General transcription factor TFIIB)
(316 aa)

Score: 161 bits (408), Expect: 2.51679e-38
Length: 327, Idn/Pos/Gap = 105/172/38 (32%/52%/11%)

Query:  22 LVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSINPLLDSG-LAT  80
           LVED + GD++C++CG+V  + +ID+G EWRTF ND +A DP+RVG + NPLL  G L T
Sbjct:  23 LVEDYRAGDMICSECGLVVGDRVIDVGSEWRTFSNDKAAADPSRVGDAQNPLLSGGDLTT  82

Query:  81 SISQGPAGANALNERLARAQSRNVLDANDRYVTECYNRISYLCERSGLPQLVKDRACELL 140
            I +G   A+      ++ Q+R  + ++DR +   +  I+ + +R  LP+ + DR   L 
Sbjct:  83 MIGKGTGSASFDEFGNSKYQNRRTMSSSDRAMMNAFKEITNMSDRINLPRNIIDRTNNLF 142

Query: 141 RLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRTFNEISVIVSVAKSRV 200
           +  Y+  +L         + R ++  +I SA L+IACR EG PRTF EI  +  ++K  +
Sbjct: 143 KQVYEQKSL---------KGRSND--AIASACLYIACRQEGVPRTFKEICAVSRISKKEI 191

Query: 201 AA----YVKAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPNIVRSLVNQVARAAAEKDG 256
                  +KA+E ++        + TT DF+SRFCS L +   V+     +AR A E D 
Sbjct: 192 GRCFKLILKALETNVD-------LITTGDFMSRFCSNLGLTKQVQMAATHIARKAVELDL 244

Query: 257 IHGRTLVSIAAGAIYFVLLLWRETCPQSIPATLRVSDEALVNRIAEVSGITEGVVKTVAS 316
           + GR+ +S+AA AIY               A+   +++     I +++G+ +  ++  + 
Sbjct: 245 VPGRSPISVAAAAIYM--------------ASQASAEKRTQKEIGDIAGVADVTIRQ-SY 289

Query: 317 RIRQYRDRGLLPPDWVRRFPSRLEPEL 343
           R+   R   L P D+    P    P+L
Sbjct: 290 RLIYPRAPDLFPADFKFDTPVDKLPQL 316

ref|XP_422356.1| PREDICTED: similar to Transcription initiation factor IIB (General transcription factor TFIIB) (RNA polymerase II alpha initiation factor) [Gallus gallus]
(468 aa)

Score: 160 bits (405), Expect: 6.09472e-38
Length: 327, Idn/Pos/Gap = 105/170/38 (32%/51%/11%)

Query:  22 LVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSINPLLDSG-LAT  80
           LVED + GD++C++CG+V  + +ID+G EWRTF ND +  DP+RVG + NPLL  G L+T
Sbjct: 175 LVEDYRAGDMICSECGLVVGDRVIDVGSEWRTFSNDKATKDPSRVGDTQNPLLSDGDLST 234

Query:  81 SISQGPAGANALNERLARAQSRNVLDANDRYVTECYNRISYLCERSGLPQLVKDRACELL 140
            I +G   A+      ++ Q+R  + ++DR +   +  I+ + +R  LP+ + DR   L 
Sbjct: 235 MIGKGTGAASFDEFGNSKYQNRRTMSSSDRAMMNAFKEITNMADRINLPRNIVDRTNNLF 294

Query: 141 RLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRTFNEISVIVSVAKSRV 200
           +  Y+  +L           +     +I SA L+IACR EG PRTF EI  +  ++K  +
Sbjct: 295 KQVYEQKSL-----------KGRSNDAIASACLYIACRQEGVPRTFKEICAVSRISKKEI 343

Query: 201 AA----YVKAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPNIVRSLVNQVARAAAEKDG 256
                  +KA+E S+        + TT DF+SRFCS L +P  V+     +AR A E D 
Sbjct: 344 GRCFKLILKALETSVD-------LITTGDFMSRFCSNLGLPKQVQMAATHIARKAVELDL 396

Query: 257 IHGRTLVSIAAGAIYFVLLLWRETCPQSIPATLRVSDEALVNRIAEVSGITEGVVKTVAS 316
           + GR+ +S+AA AIY               A+   +++     I +++G+ +  ++  + 
Sbjct: 397 VPGRSPISVAAAAIYM--------------ASQASAEKRTQKEIGDIAGVADVTIRQ-SY 441

Query: 317 RIRQYRDRGLLPPDWVRRFPSRLEPEL 343
           R+   R   L P D+    P    P+L
Sbjct: 442 RLIYPRAPDLFPADFKFDTPVDKLPQL 468

gb|EAL02759.1| likely transcription factor TFIIB [Candida albicans SC5314]
gb|EAL02479.1| likely transcription factor TFIIB [Candida albicans SC5314]
(344 aa)

Score: 159 bits (403), Expect: 9.40553e-38
Length: 349, Idn/Pos/Gap = 111/176/44 (31%/50%/12%)

Query:   9 DVPDVCGECG--STDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDD-SAYDPNR  65
           +V   C EC     DLVE    GD+VC  CG+V ++ ++D   EWRTF NDD +  DP+R
Sbjct:  18 NVTLTCPECKIFPPDLVERFSEGDIVCGSCGLVLSDRVVDTRSEWRTFSNDDQNGDDPSR  77

Query:  66 VGGSINPLLDS-GLATSISQGPAGANALNERLARAQSRNVLDANDRYVTECYNRISYLCE 124
           VG + NPLLD+  L+T IS  P    A  E L+RAQS++++D  D  +   Y +IS +C+
Sbjct:  78 VGDAGNPLLDTEDLSTMISYAPDSTKAGRE-LSRAQSKSLVDKKDNALAAAYIKISQMCD 136

Query: 125 RSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPR 184
              LP++V D A E+ ++ YD   L           R     SI++A++FI CR     R
Sbjct: 137 GYQLPKIVSDGAKEVYKMVYDEKPL-----------RGKSQESIMAASIFIGCRKANVAR 185

Query: 185 TFNEISVIVSVAKSRVAAYVKAMEMSIGEAAKIS---------RIRTT----DDFVSRFC 231
           +F EI  + +V +  +    K M+  I E    +          I+TT    +D + RFC
Sbjct: 186 SFKEIWALTNVPRKEIGKVFKIMDKIIREKNAANPNAAYYGQDSIQTTQTSAEDLIRRFC 245

Query: 232 SYLEIPNIVRSLVNQVARAAAEKDGIHGRTLVSIAAGAIYFVLLLWRETCPQSIPATLRV 291
           S+L +   V +    +AR   E   + GR+  +IAA  IY   L++    P S       
Sbjct: 246 SHLGVNTQVTNGAEYIARRCKEVGVLAGRSPTTIAATVIYMASLVFGFDLPPS------- 298

Query: 292 SDEALVNRIAEVSGITEGVVKTVASRIRQYRDRGLLPPDWVRRFPSRLE 340
                  +I++ +G+++G +KT    + + +++ L+ P W+     +LE
Sbjct: 299 -------KISDKTGVSDGTIKTSYKYMYEEKEQ-LIDPSWIESGKVKLE 339

gb|AAG24202.2| Tfii(two)b (general transcription factor) protein 1 [Caenorhabditis elegans]
ref|NP_503146.1| TFII(Two)B general transcription factor (33.1 kD) (ttb-1) [Caenorhabditis elegans]
sp|O16991|TF2B_CAEEL Transcription initiation factor IIB (General transcription factor TFIIB)
(306 aa)

Score: 156 bits (395), Expect: 9.02383e-37
Length: 272, Idn/Pos/Gap = 106/154/24 (38%/56%/8%)

Query:   1 MSAPTMERDVPDVCGECGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSA  60
           MSAP      PDV        L+ED + GDLVC  CG+V  + L+D+G EWR+F N+ S 
Sbjct:   1 MSAPVQCPIHPDV-------HLIEDHRAGDLVCPACGLVVGDRLVDVGTEWRSFSNERSG  53

Query:  61 YDPNRVGGSINPLLDSG-LATSISQGPAGANALNERLARAQSRNVLDANDRYVTECYNRI 119
            DP+RVG   NPLL  G L+T+I+ G  G+++ N  LA AQ R  ++  DR +T   + I
Sbjct:  54 NDPSRVGAPENPLLSGGDLSTTIAVGFGGSDSDNS-LANAQ-RKSMNNTDRQMTAAMSLI 111

Query: 120 SYLCERSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRN 179
             + ER  LP+ ++D A    R++ D L   A     R +  E + A    A L+IACR 
Sbjct: 112 REMSERIHLPRNIQDSAS---RIFKDVLESKA----LRGKNNEAQAA----ACLYIACRK 160

Query: 180 EGFPRTFNEISVIVSVAKSRVAAYVKAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPNI 239
           +G PRTF EI  +  V+K  +    K +  S+     + +I T+ DF+SRFC  L +PN 
Sbjct: 161 DGVPRTFKEICAVSRVSKKEIGRCFKIIVRSL--ETNLEQI-TSADFMSRFCGNLSLPNS 217

Query: 240 VRSLVNQVARAAAEKDGIHGRTLVSIAAGAIY 271
           +++   ++A+ A + D + GRT +SIAA AIY
Sbjct: 218 IQAAATRIAKCAVDMDLVAGRTPISIAAAAIY 249

emb|CAG88192.1| unnamed protein product [Debaryomyces hansenii CBS767]
ref|XP_459946.1| unnamed protein product [Debaryomyces hansenii]
(346 aa)

Score: 155 bits (393), Expect: 1.29184e-36
Length: 344, Idn/Pos/Gap = 109/176/44 (31%/51%/12%)

Query:  14 CGECG--STDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDD-SAYDPNRVGGSI  70
           C EC     DL+E    GD+VC  CG+V ++ ++D   EWRTF NDD +  DP+RVG + 
Sbjct:  25 CPECKIFPPDLIERFSEGDIVCGSCGLVLSDRVVDTRSEWRTFSNDDQNGDDPSRVGDAG  84

Query:  71 NPLLDS-GLATSISQGPAGANALNERLARAQSRNVLDANDRYVTECYNRISYLCERSGLP 129
           NPLLD+  L+T IS  P       E L RAQS++++D  D  +   Y+++S +C+   LP
Sbjct:  85 NPLLDTEDLSTMISYVPENTKVGRE-LNRAQSKSLVDKKDNALAAAYSKLSQMCDGYQLP 143

Query: 130 QLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRTFNEI 189
           ++V+D A E+ +L Y+   L           +     SI++AA+FI CR     R+F EI
Sbjct: 144 KIVQDGAKEVYKLVYEERPL-----------KGKSQESIMAAAIFIGCRKAKVARSFKEI 192

Query: 190 SVIVSVAKSRVAAYVKAMEMSIGEAAKIS---------RIRTT----DDFVSRFCSYLEI 236
             + +V +  +    K M   I E    +          ++TT    +D + RFCS+L +
Sbjct: 193 WALTNVPRKEIGKVFKIMNKIIQEKNAANPNAYSLIQDNMQTTQTSAEDLIRRFCSHLGL 252

Query: 237 PNIVRSLVNQVARAAAEKDGIHGRTLVSIAAGAIYFVLLLWRETCPQSIPATLRVSDEAL 296
              V +    +AR   +   + GR+ ++IAA  IY   L++         A L+ S    
Sbjct: 253 STQVTNAAEHIARRCKDVGVLAGRSPITIAATVIYMAALVF--------GADLQPS---- 300

Query: 297 VNRIAEVSGITEGVVKTVASRIRQYRDRGLLPPDWVRRFPSRLE 340
             +IA+ +G+++G +KT    + + ++R L+ P WV     +LE
Sbjct: 301 --KIADKTGVSDGTIKTSYKVMYEEKER-LIDPYWVESGKVKLE 341

emb|CAE62359.1| Hypothetical protein CBG06439 [Caenorhabditis briggsae]
(306 aa)

Score: 155 bits (392), Expect: 2.02714e-36
Length: 272, Idn/Pos/Gap = 102/151/24 (37%/55%/8%)

Query:   1 MSAPTMERDVPDVCGECGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSA  60
           MSAP      PDV        L+ED + GDLVC  CG+V  + L+D+G EWR+F N+ S 
Sbjct:   1 MSAPVQCPVHPDV-------HLIEDHRAGDLVCPACGLVVGDRLVDVGTEWRSFSNERSG  53

Query:  61 YDPNRVGGSINPLLDSG-LATSISQGPAGANALNERLARAQSRNVLDANDRYVTECYNRI 119
            DP+RVG   NPLL  G L+T+I+ G  G+++ N  LA AQ R  ++  DR +T   + I
Sbjct:  54 NDPSRVGAPENPLLTGGDLSTTIAVGFGGSDSDNS-LANAQ-RKSMNNTDRQMTAAMSLI 111

Query: 120 SYLCERSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRN 179
             + ER  LP+ ++D A  + +   D   L      A+A           +A L+IACR 
Sbjct: 112 REMSERIHLPRNIQDNASRIFKDVLDSRALRGKNNEAQA-----------AACLYIACRK 160

Query: 180 EGFPRTFNEISVIVSVAKSRVAAYVKAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPNI 239
           +G PRTF EI  +  V+K  +    K +  ++     + +I T+ DF+SRFC  L +PN 
Sbjct: 161 DGVPRTFKEICAVSRVSKKEIGRCFKIIIRNL--ETNLEQI-TSADFMSRFCGNLYLPNS 217

Query: 240 VRSLVNQVARAAAEKDGIHGRTLVSIAAGAIY 271
           +++   ++A+ A + D + GRT +SIAA AIY
Sbjct: 218 IQAAATRIAKRAVDMDLVAGRTPISIAAAAIY 249

emb|CAB11044.1| SPAC16E8.16 [Schizosaccharomyces pombe]
ref|NP_594229.1| transcription initiation factor TFIIB [Schizosaccharomyces pombe]
sp|O13749|TF2B_SCHPO Transcription initiation factor IIB (General transcription factor TFIIB)
pir||T37796 probable transcription initiation factor TFIIB subunit - fission yeast (Schizosaccharomyces pombe)
(340 aa)

Score: 154 bits (389), Expect: 4.08574e-36
Length: 359, Idn/Pos/Gap = 111/175/48 (30%/48%/13%)

Query:   4 PTMERDVPDVCGEC--GSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAY  61
           PT    V  +C EC     +LVE+  +GD VC  CG+V  + +ID   EWRTF N D A 
Sbjct:  10 PTSMLSVKMICSECREDPPNLVEEFSSGDTVCGSCGLVLGDRIIDTRSEWRTFSNSDEAS  69

Query:  62 -DPNRVGGSINPLLD-SGLATSISQGPAGANALNERLARAQSRNVLDANDRYVTECYNRI 119
            DP+RVG   NPLL+ S L T+IS    GA A+   LA+AQ R+V    ++ +   Y  I
Sbjct:  70 GDPSRVGKVANPLLNGSQLDTTISSYD-GAGAM---LAKAQGRSVQVRGEKNLLTAYKEI 125

Query: 120 SYLCERSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRN 179
             +C+   LP+++ D A +L +   DH  L           +   + SII+A ++IACR 
Sbjct: 126 GAMCDAISLPKVIADTAKQLYKRVDDHKAL-----------KGKSSQSIIAACIYIACRQ 174

Query: 180 EGFPRTFNEISVIVSVAKSRVAAYVKAMEMSIGEAAKI--------------SRIRTTDD 225
              PRTF EI  + +V K  +    K ++  + E   +              S   + +D
Sbjct: 175 GKVPRTFMEICTLTNVPKKEIGRVYKTLQRMLTEGGALHNSVDALKGHEYIQSSSTSAED 234

Query: 226 FVSRFCSYLEIPNIVRSLVNQVARAAAEKDGIHGRTLVSIAAGAIYFVLLLWRETCPQSI 285
            + RFC+ L +P  V+S   ++AR A  +  + GR+ +SIAA  IY +  L         
Sbjct: 235 LMVRFCNRLMLPMSVQSAAAELARRAGLQGTLAGRSPISIAASGIYMISAL------MGY 288

Query: 286 PATLRVSDEALVNRIAEVSGITEGVVKTVASRIRQYRDRGLLPPDWVRRFPSRLEPELP 344
           P T +         I+EV+G+++  ++ +A ++     + L+ P W+      ++  LP
Sbjct: 289 PKTPK--------EISEVTGVSDSTIR-IAYKLLHAERKELIDPKWIANKAGNMDAMLP 338

emb|CAG61530.1| unnamed protein product [Candida glabrata CBS138]
ref|XP_448567.1| unnamed protein product [Candida glabrata]
(363 aa)

Score: 154 bits (389), Expect: 4.15449e-36
Length: 337, Idn/Pos/Gap = 108/169/49 (32%/50%/14%)

Query:   1 MSAP--TMERDV----PDV-----CGECG--STDLVEDTKNGDLVCAQCGVVAAELLIDL  47
           MSAP  ++ R V    P++     C EC      +VE    GD+VCA CG+V ++ L+D 
Sbjct:   1 MSAPVTSLRRSVGRKGPNLNIVLTCPECKVYPPKIVERFSEGDVVCALCGLVLSDKLVDT  60

Query:  48 GHEWRTFENDD-SAYDPNRVGGSINPLLD-SGLATSISQGPAGANALNERLARAQSRNVL 105
             EWRTF NDD +  DP+RVG + NPLLD + L+T I QG        + L RAQ +NVL
Sbjct:  61 RSEWRTFSNDDQNGDDPSRVGEASNPLLDGNNLSTKIGQGETTDMRFTKELNRAQGKNVL 120

Query: 106 DANDRYVTECYNRISYLCERSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDET 165
           D  D  +   + +I+ LC+ S LP++VKD A E  +L +D   L           +   +
Sbjct: 121 DKKDNEIQAAFAKITMLCDASELPKIVKDCAKEAYKLCHDEKAL-----------KGKSS 169

Query: 166 ASIISAALFIACRNEGFPRTFNEISVIVSVAKSRVAAYVKAMEMSIGEAAKISRIRTTDD 225
            SI++A++ + CR     RTF EI  I+ V        +  M+  + E +    I+   D
Sbjct: 170 ESIMAASILLGCRRAEVARTFKEIQSIIHVKTKEFGKTLGIMKNILREKSADGFIKIDTD 229

Query: 226 ---------FVSRFCSYLEIPNIVRSLVNQVARAAAEKDGIHGRTLVSIAAGAIYFVLLL 276
                    ++ RFCS+L +P  V +     A+   E + I G++ ++IA  +IY  +LL
Sbjct: 230 NMSGAQNLTYIPRFCSHLGLPMQVTTSAEYTAKKCKEIEEIAGKSPITIAVVSIYLNILL 289

Query: 277 WRETCPQSIPATLRVSDEALVNRIAEVSGITEGVVKT 313
           ++      IP +          R+ ++  +TEG +K+
Sbjct: 290 FK------IPVS--------AARVGQILQVTEGTIKS 312

gb|AAT93251.1| YPR086W [Saccharomyces cerevisiae]
(345 aa)

Score: 152 bits (384), Expect: 1.70182e-35
Length: 328, Idn/Pos/Gap = 100/164/38 (30%/50%/11%)

Query:  14 CGECG--STDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDD-SAYDPNRVGGSI  70
           C EC      +VE    GD+VCA CG+V ++ L+D   EWRTF NDD +  DP+RVG + 
Sbjct:  24 CPECKVYPPKIVERFSEGDVVCALCGLVLSDKLVDTRSEWRTFSNDDHNGDDPSRVGEAS  83

Query:  71 NPLLD-SGLATSISQGPAGANALNERLARAQSRNVLDANDRYVTECYNRISYLCERSGLP 129
           NPLLD + L+T I +G        + L +AQ +NV+D  D  V   + +I+ LC+ + LP
Sbjct:  84 NPLLDGNNLSTRIGKGETTDMRFTKELNKAQGKNVMDKKDNEVQAAFAKITMLCDAAELP 143

Query: 130 QLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRTFNEI 189
           ++VKD A E  +L +D  TL    +            SI++A++ I CR     RTF EI
Sbjct: 144 KIVKDCAKEAYKLCHDEKTLKGKSME-----------SIMAASILIGCRRAEVARTFKEI 192

Query: 190 SVIVSVAKSRVAAYVKAMEMSIGEAAKISRIRTTDD---------FVSRFCSYLEIPNIV 240
             ++ V        +  M+  +   ++   ++   D         ++ RFCS+L +P  V
Sbjct: 193 QSLIHVKTKEFGKTLNIMKNILRGKSEDGFLKIDTDNMSGAQNLTYIPRFCSHLGLPMQV 252

Query: 241 RSLVNQVARAAAEKDGIHGRTLVSIAAGAIYFVLLLWRETCPQSIPATLRVSDEALVNRI 300
            +     A+   E   I G++ ++IA  +IY  +LL++      IP T          ++
Sbjct: 253 TTSAEYTAKKCKEIKEIAGKSPITIAVVSIYLNILLFQ------IPIT--------AAKV 298

Query: 301 AEVSGITEGVVKTVASRIRQYRDRGLLP 328
            +   +TEG +K+    + ++RD+ + P
Sbjct: 299 GQTLQVTEGTIKSGYKILYEHRDKLVDP 326

gb|AAB68135.1| Sua7p: Transcription initiation factor IIB (Swiss Prot. accession number P29055) [Saccharomyces cerevisiae]
sp|P29055|TF2B_YEAST Transcription initiation factor IIB (General transcription factor TFIIB) (Transcription factor E)
ref|NP_015411.1| Sua7p [Saccharomyces cerevisiae]
gb|AAA35126.1| Sua7
(345 aa)

Score: 152 bits (384), Expect: 1.77432e-35
Length: 328, Idn/Pos/Gap = 100/164/38 (30%/50%/11%)

Query:  14 CGECG--STDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDD-SAYDPNRVGGSI  70
           C EC      +VE    GD+VCA CG+V ++ L+D   EWRTF NDD +  DP+RVG + 
Sbjct:  24 CPECKVYPPKIVERFSEGDVVCALCGLVLSDKLVDTRSEWRTFSNDDHNGDDPSRVGEAS  83

Query:  71 NPLLD-SGLATSISQGPAGANALNERLARAQSRNVLDANDRYVTECYNRISYLCERSGLP 129
           NPLLD + L+T I +G        + L +AQ +NV+D  D  V   + +I+ LC+ + LP
Sbjct:  84 NPLLDGNNLSTRIGKGETTDMRFTKELNKAQGKNVMDKKDNEVQAAFAKITMLCDAAELP 143

Query: 130 QLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRTFNEI 189
           ++VKD A E  +L +D  TL    +            SI++A++ I CR     RTF EI
Sbjct: 144 KIVKDCAKEAYKLCHDEKTLKGKSME-----------SIMAASILIGCRRAEVARTFKEI 192

Query: 190 SVIVSVAKSRVAAYVKAMEMSIGEAAKISRIRTTDD---------FVSRFCSYLEIPNIV 240
             ++ V        +  M+  +   ++   ++   D         ++ RFCS+L +P  V
Sbjct: 193 QSLIHVKTKEFGKTLNIMKNILRGKSEDGFLKIDTDNMSGAQNLTYIPRFCSHLGLPMQV 252

Query: 241 RSLVNQVARAAAEKDGIHGRTLVSIAAGAIYFVLLLWRETCPQSIPATLRVSDEALVNRI 300
            +     A+   E   I G++ ++IA  +IY  +LL++      IP T          ++
Sbjct: 253 TTSAEYTAKKCKEIKEIAGKSPITIAVVSIYLNILLFQ------IPIT--------AAKV 298

Query: 301 AEVSGITEGVVKTVASRIRQYRDRGLLP 328
            +   +TEG +K+    + ++RD+ + P
Sbjct: 299 GQTLQVTEGTIKSGYKILYEHRDKLVDP 326

emb|CAG81664.1| unnamed protein product [Yarrowia lipolytica CLIB99]
ref|XP_501365.1| hypothetical protein [Yarrowia lipolytica]
(324 aa)

Score: 149 bits (377), Expect: 9.89699e-35
Length: 324, Idn/Pos/Gap = 104/171/35 (32%/52%/10%)

Query:   9 DVPDVCGECG--STDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYD-PNR  65
           +V  +C EC     D+VE    GD+VC QCG+V ++ ++D   EWRTF NDD   D P+R
Sbjct:   8 NVTLMCPECKILPPDIVERFAEGDMVCGQCGLVLSDRVVDTRSEWRTFSNDDQGSDDPSR  67

Query:  66 VGGSINPLLD-SGLATSISQGPAGANALNERLARAQSRNVLDANDRYVTECYNRISYLCE 124
           VG ++NPLL+ S L T IS G  G+ ++   L R QSR++ D  D  ++  Y +IS +C+
Sbjct:  68 VGDAMNPLLEGSQLNTIISFGAPGS-SVGRDLNRTQSRSLQDKKDAALSAVYAKISQICD 126

Query: 125 RSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPR 184
              LP++V D A E+ +L +D             R R     +II+  +FIACR+    R
Sbjct: 127 GISLPRVVSDAAKEVYKLVHDD-----------KRLRGKTPDAIIATVIFIACRHANVQR 175

Query: 185 TFNEISVIVSVAKSRVAAYVKAMEMSIGEAAKISRIRTTDD----FVSRFCSYLEIPNIV 240
           TF EI  + +V+K  +   ++ M+  + E   I   R+T       + R+CS+L + + V
Sbjct: 176 TFQEIGALTNVSKKEIRRTLELMKRLL-EGTNIQAFRSTQTNPGALMPRYCSHLGLNSQV 234

Query: 241 RSLVNQVARAAAEKDGIHGRTLVSIAAGAIYFVLLLWRETCPQSIPATLRVSDEALVNRI 300
            +L   + + A E   + GR+ +S+AA AIY    L+               ++    R+
Sbjct: 235 ANLAEDIVKRAKEIGTLDGRSPISVAAAAIYMAAALY--------------GNDMSAQRV 280

Query: 301 AEVSGITEGVVKTVASRIRQYRDR 324
           +E +G+++G +KT    + + R++
Sbjct: 281 SEKTGVSDGTIKTSYKHLYEAREK 304

gb|AAH82943.1| LOC494830 protein [Xenopus laevis]
(316 aa)

Score: 147 bits (371), Expect: 5.52044e-34
Length: 327, Idn/Pos/Gap = 103/171/38 (31%/52%/11%)

Query:  22 LVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSINPLLDSG-LAT  80
           LVED + GD++C++ G+V  + ++D+G EWRTF ND +A DP+RVG + NPLL  G L T
Sbjct:  23 LVEDYRAGDMICSESGLVVGDRVVDVGSEWRTFSNDKAAKDPSRVGDAQNPLLSGGDLTT  82

Query:  81 SISQGPAGANALNERLARAQSRNVLDANDRYVTECYNRISYLCERSGLPQLVKDRACELL 140
            I +G   A+      ++ Q+R  + ++DR +   +  I+ + +R  LP+ + DR   L 
Sbjct:  83 MIGKGTGAASFDEFGNSKYQNRRAMSSSDRAMMNAFKEITTMADRINLPRNIVDRTNNLF 142

Query: 141 RLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRTFNEISVIVSVAKSRV 200
           +  Y+  +L         + R ++  +I SA L+IACR EG PRTF EI  +  ++K  +
Sbjct: 143 KQVYEQKSL---------KGRSND--AIASACLYIACRQEGVPRTFKEICAVSRISKKEI 191

Query: 201 AA----YVKAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPNIVRSLVNQVARAAAEKDG 256
                  +KA+E ++        + TT DF+SRFCS L +   V+     +AR A E D 
Sbjct: 192 GRCFKLILKALETNVD-------LITTGDFMSRFCSNLGLTKQVQMAATHIARKAVELDL 244

Query: 257 IHGRTLVSIAAGAIYFVLLLWRETCPQSIPATLRVSDEALVNRIAEVSGITEGVVKTVAS 316
           + GR+ +S+AA AIY               A+   +++     I +++G+ +  ++  + 
Sbjct: 245 VPGRSPISVAAAAIYM--------------ASQASAEKRTQKEIGDIAGVADVTIRQ-SY 289

Query: 317 RIRQYRDRGLLPPDWVRRFPSRLEPEL 343
           R+   R   L P D+    P    P+L
Sbjct: 290 RLIYPRAPDLFPADFKFDTPVDKLPQL 316

emb|CAD25470.1| TRANSCRIPTION INITIATION FACTOR TFIIB [Encephalitozoon cuniculi GB-M1]
ref|NP_585866.1| TRANSCRIPTION INITIATION FACTOR TFIIB [Encephalitozoon cuniculi GB-M1]
sp|Q8SRP3|TF2B_ENCCU Transcription initiation factor IIB (General transcription factor TFIIB)
(312 aa)

Score: 147 bits (370), Expect: 6.05109e-34
Length: 268, Idn/Pos/Gap = 92/142/21 (34%/52%/7%)

Query:  14 CGECGST-DLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSINP  72
           C +CG T ++VED KNG  VC +CG +    +ID G EWR+F  D +  DP R+G + NP
Sbjct:  14 CSDCGETQNIVEDYKNGYHVCGRCGCIVGNRIIDEGSEWRSF-GDSNKVDPCRIGSASNP  72

Query:  73 LLDS-GLATSISQGPAGANALNERLARAQSRNVLDANDRYVTECYNRISYLCERSGLPQL 131
            L+S  L T IS G  G N+    L++ Q +N +   +R +    N I+  CERS L + 
Sbjct:  73 YLESEQLDTMISTG-GGMNSY--VLSKIQMKNSMRGPERALKHGMNLITAFCERSNLSRT 129

Query: 132 VKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRTFNEISV 191
           + DRA  + +            +  R   +      I++A ++IACR E  PRTF EISV
Sbjct: 130 IIDRAHYIFK-----------NIEERKLLKGKNVEGIVAACIYIACRQEECPRTFKEISV 178

Query: 192 IVSVAKSRVAAYVKAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPNIVRSLVNQVARAA 251
           + +V K  +    K +   +   A +S    T++ ++RFCS L +   ++ +  ++A+AA
Sbjct: 179 MTAVQKREIGRCFKLISPHLERMATMS----TENIIARFCSDLNLNIKIQKIATEIAKAA 234

Query: 252 AEKDGIHGRTLVSIAAGAIYFVLLLWRE 279
            E   + G++  SIAA  IY V  L+ E
Sbjct: 235 HELGCLAGKSPDSIAAAVIYMVTNLFPE 262

gb|AAS51927.1| ADR007Cp [Ashbya gossypii ATCC 10895]
ref|NP_984103.1| ADR007Cp [Eremothecium gossypii]
(354 aa)

Score: 145 bits (367), Expect: 1.41725e-33
Length: 307, Idn/Pos/Gap = 101/159/32 (32%/51%/10%)

Query:   8 RDVPDV-----CGECG--STDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDD-S  59
           R VP++     C EC      +VE    GD+VCA CG+V ++ ++D   EWRTF NDD +
Sbjct:  17 RKVPNLNIVISCPECKVYPPKVVERFSEGDIVCALCGLVLSDRIVDTRSEWRTFFNDDQN  76

Query:  60 AYDPNRVGGSINPLLDSG-LATSISQGPAGANALNERLARAQSRNVLDANDRYVTECYNR 118
             DP+RVG + NPLLD   L+T I Q       L   L RAQS++++D  D  +   Y +
Sbjct:  77 GDDPSRVGEASNPLLDGNHLSTRIGQVQGSDVKLTRELNRAQSKSIVDKKDNELQAAYAK 136

Query: 119 ISYLCERSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACR 178
           I+ +C+ + LP++VKD A E  +L ++   L           +     SI+++ + + CR
Sbjct: 137 ITMMCDAAELPRIVKDCAKEAYKLCFEERAL-----------KGKSQESIMASVILVGCR 185

Query: 179 NEGFPRTFNEISVIVSVAKSRVAAYVKAMEMSIGE----------AAKISRIRT-TDDFV 227
                RTF EI  + +V K  +      ++  + E           A IS  +T  + F+
Sbjct: 186 RAEVGRTFKEILSLTNVRKKEIGKTFNIIKKILREKNDSGFANVDTANISTGQTNAETFI 245

Query: 228 SRFCSYLEIPNIVRSLVNQVARAAAEKDGIHGRTLVSIAAGAIYFVLLLWR-ETCPQSIP 286
            RFCS+L +   V +    +A+ A + + + GR+ ++IAA AIY   LL+R    P  I 
Sbjct: 246 PRFCSHLGLSVQVANAAEYIAKHAKDINVLAGRSPLTIAASAIYMANLLFRYNITPSQIS 305

Query: 287 ATLRVSD 293
           ATL+V++
Sbjct: 306 ATLQVTE 312

ref|XP_590886.1| PREDICTED: similar to Transcription initiation factor IIB (General transcription factor TFIIB) (S300-II), partial [Bos taurus]
(274 aa)

Score: 141 bits (355), Expect: 3.32035e-32
Length: 305, Idn/Pos/Gap = 98/154/38 (32%/50%/12%)

Query:  44 LIDLGHEWRTFENDDSAYDPNRVGGSINPLLDSG-LATSISQGPAGANALNERLARAQSR 102
           +ID+G EWRTF ND +  DP+RVG S NPLL  G L+T I +G   A+      +  Q+R
Sbjct:   3 VIDVGSEWRTFSNDKATKDPSRVGDSQNPLLSDGDLSTMIGKGTGAASFDEFGNSNYQNR  62

Query: 103 NVLDANDRYVTECYNRISYLCERSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFRE 162
             + ++DR +   +  I+ + +R  LP+ + DR   L +  Y+  +L     + RA    
Sbjct:  63 RTMSSSDRAMMNAFKEITTMADRINLPRNIVDRTNNLFKQVYEQKSL-----KGRA---- 113

Query: 163 DETASIISAALFIACRNEGFPRTFNEISVIVSVAKSRVAA----YVKAMEMSIGEAAKIS 218
               +I SA L+IACR EG PRTF EI  +  ++K  +       +KA+E S+       
Sbjct: 114 --NDAIASACLYIACRQEGVPRTFKEICAVSRISKKEIGRCFKLILKALETSVD------ 165

Query: 219 RIRTTDDFVSRFCSYLEIPNIVRSLVNQVARAAAEKDGIHGRTLVSIAAGAIYFVLLLWR 278
            + TT DF+SRFCS L +P  V+     +AR A E D + GR+ +S+AA AIY       
Sbjct: 166 -LITTGDFMSRFCSNLCLPKQVQMAATHIARKAVELDLVPGRSPISVAAAAIYM------ 218

Query: 279 ETCPQSIPATLRVSDEALVNRIAEVSGITEGVVKTVASRIRQYRDRGLLPPDWVRRFPSR 338
                   A+   +++     I +++G+ +  ++  + R+   R   L P D+    P  
Sbjct: 219 --------ASQASAEKRTQKEIGDIAGVADVTIRQ-SYRLIYPRAPDLFPTDFKFDTPVD 269

Query: 339 LEPEL 343
             P+L
Sbjct: 270 KLPQL 274

emb|CAH00767.1| TF2B_KLULA [Kluyveromyces lactis NRRL Y-1140]
ref|XP_453671.1| TF2B_KLULA [Kluyveromyces lactis]
pir||S34953 transcription initiation factor IIB - yeast (Kluyveromyces marxianus var. lactis)
sp|Q05959|TF2B_KLULA Transcription initiation factor IIB (General transcription factor TFIIB)
gb|AAA35258.1| human TFIIB homologue protein
(357 aa)

Score: 137 bits (345), Expect: 4.87525e-31
Length: 296, Idn/Pos/Gap = 91/153/27 (30%/51%/9%)

Query:  14 CGECG--STDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDD-SAYDPNRVGGSI  70
           C EC      +VE    GD+VCA CG+V ++ ++D   EWRTF NDD +  DP+RVG + 
Sbjct:  28 CPECKVYPPKVVERFSEGDIVCALCGLVLSDRIVDTRSEWRTFSNDDQNGDDPSRVGEAS  87

Query:  71 NPLLDSG-LATSISQGPAGANALNERLARAQSRNVLDANDRYVTECYNRISYLCERSGLP 129
           NPLLD   L T I Q       +   L RAQS++++D  D  +   Y +I+ +C+ + LP
Sbjct:  88 NPLLDGNHLTTRIGQAQGSDARVTRDLNRAQSKSIVDKKDNELQAAYAKITMMCDAAELP 147

Query: 130 QLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRTFNEI 189
           ++VKD A E  +L ++   L           +     SI+++ + + CR     R+F EI
Sbjct: 148 KIVKDCAKEAYKLCFEERVL-----------KGKSQESIMASVILVGCRRAEVGRSFKEI 196

Query: 190 SVIVSVAKSRVAAYVKAMEMSIGE----------AAKISRIRTT-DDFVSRFCSYLEIPN 238
             + +V K  +      ++  + E           + I+  +T+ + F+ RFCS+L +  
Sbjct: 197 LSLTNVRKKEIGKTFTIIKNILREKNDRGFANIDTSNITTGQTSAETFIPRFCSHLGLSV 256

Query: 239 IVRSLVNQVARAAAEKDGIHGRTLVSIAAGAIYFVLLLWR-ETCPQSIPATLRVSD 293
            V +    +A+ + + + + GR+ ++IAA AIY   LL++    P  I  TL+V++
Sbjct: 257 QVANAAEYIAKHSKDVNVLAGRSPITIAAAAIYMATLLFKLNISPTRISQTLQVTE 312

gb|AAR28002.1| TFIIB1 [Arabidopsis thaliana]
gb|AAM63705.1| transcription factor IIB (TFIIB) [Arabidopsis thaliana]
gb|AAM91169.1| transcription factor IIB [Arabidopsis thaliana]
gb|AAM13059.1| transcription factor IIB [Arabidopsis thaliana]
gb|AAB84344.1| transcription factor IIB (TFIIB) [Arabidopsis thaliana]
ref|NP_181694.1| transcription initiation factor IIB-1 / general transcription factor TFIIB-1 (TFIIB1) [Arabidopsis thaliana]
pir||T00819 transcription initiation factor IIB - Arabidopsis thaliana
gb|AAB09755.1| transcription factor TFIIB [Arabidopsis thaliana]
sp|P48512|TF2B1_ARATH Transcription initiation factor IIB-1 (General transcription factor TFIIB-1) (AtTFIIB1)
(312 aa)

Score: 134 bits (338), Expect: 3.21322e-30
Length: 327, Idn/Pos/Gap = 108/160/42 (33%/48%/12%)

Query:  14 CGECG-STDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSINP  72
           C +C   T+LV D   GD +C++CG+V     ID   EWRTF N+ S  DPNRVGG  NP
Sbjct:   6 CTDCKKETELVVDHSAGDTLCSECGLVLESHSIDETSEWRTFANESSNSDPNRVGGPTNP  65

Query:  73 LL-DSGLATSISQGPAGANA--LNERLARAQSRNVLDANDRYVTECYNRISYLCERSGLP 129
           LL DS L T I++ P G++   L+  L R Q+RN    +DR + + +  I+ + ER GL 
Sbjct:  66 LLADSALTTVIAK-PNGSSGDFLSSSLGRWQNRN--SNSDRGLIQAFKTIATMSERLGLV 122

Query: 130 QLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRTFNEI 189
             +KDRA EL +   D  +       +R R ++    ++ +A L+IACR E  PRT  EI
Sbjct: 123 ATIKDRANELYKRLEDQKS-------SRGRNQD----ALYAACLYIACRQEDKPRTIKEI 171

Query: 190 SVIVSVAKS----RVAAY-VKAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPNIVRSLV 244
            VI + A      R   Y VK + +  G++  +  I    DF+ RFCS L + N      
Sbjct: 172 CVIANGATKKEIGRAKDYIVKTLGLEPGQSVDLGTIH-AGDFMRRFCSNLAMSNHAVKAA 230

Query: 245 NQVARAAAEKDGIHGRTLVSIAAGAIYFVLLLWRETCPQSIPATLRVSDEALVNRIAEVS 304
            +  + + E D    R+ +SIAA  IY +  L                D+  +  I+  +
Sbjct: 231 QEAVQKSEEFD--IRRSPISIAAVVIYIITQL--------------SDDKKTLKDISHAT 274

Query: 305 GITEGVVKTVASRIRQYRDRGLLPPDW 331
           G+ EG ++     +  Y     + P W
Sbjct: 275 GVAEGTIRNSYKDL--YPHLSKIAPSW 299

emb|CAI41343.1| general transcription factor IIB [Homo sapiens]
(231 aa)

Score: 134 bits (336), Expect: 5.52685e-30
Length: 232, Idn/Pos/Gap = 83/126/28 (35%/54%/12%)

Query:  22 LVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSINPLLDSG-LAT  80
           LVED + GD++C +C     + +ID+G EWRTF ND +  DP+RVG S NPLL  G L+T
Sbjct:  23 LVEDYRAGDMICPEC-----DRVIDVGSEWRTFSNDKATKDPSRVGDSQNPLLSDGDLST  77

Query:  81 SISQGPAGANALNERLARAQSRNVLDANDRYVTECYNRISYLCERSGLPQLVKDRACELL 140
            I +G   A+      ++ Q+R  + ++DR +   +  I+ + +R  LP+ + DR   L 
Sbjct:  78 MIGKGTGAASFDEFGNSKYQNRRTMSSSDRAMMNAFKEITTMADRINLPRNIVDRTNNLF 137

Query: 141 RLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRTFNEISVIVSVAKSRV 200
           +  Y+  +L     + RA        +I SA L+IACR EG PRTF EI  +  ++K  +
Sbjct: 138 KQVYEQKSL-----KGRA------NDAIASACLYIACRQEGVPRTFKEICAVSRISKKEI 186

Query: 201 AA----YVKAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPNIVRSLVNQVA 248
                  +KA+E S+        + TT DF+SRFCS L +P  V+     +A
Sbjct: 187 GRCFKLILKALETSVD-------LITTGDFMSRFCSNLCLPKQVQMAATHIA 231

emb|CAI41342.1| general transcription factor IIB [Homo sapiens]
(224 aa)

Score: 132 bits (333), Expect: 1.30531e-29
Length: 217, Idn/Pos/Gap = 79/120/23 (36%/55%/10%)

Query:  22 LVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSINPLLDSG-LAT  80
           LVED + GD++C +CG+V  + +ID+G EWRTF ND +  DP+RVG S NPLL  G L+T
Sbjct:  22 LVEDYRAGDMICPECGLVVGDRVIDVGSEWRTFSNDKATKDPSRVGDSQNPLLSDGDLST  81

Query:  81 SISQGPAGANALNERLARAQSRNVLDANDRYVTECYNRISYLCERSGLPQLVKDRACELL 140
            I +G   A+      ++ Q+R  + ++DR +   +  I+ + +R  LP+ + DR   L 
Sbjct:  82 MIGKGTGAASFDEFGNSKYQNRRTMSSSDRAMMNAFKEITTMADRINLPRNIVDRTNNLF 141

Query: 141 RLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRTFNEISVIVSVAKSRV 200
           +  Y+  +L     + RA        +I SA L+IACR EG PRTF EI  +  ++K  +
Sbjct: 142 KQVYEQKSL-----KGRA------NDAIASACLYIACRQEGVPRTFKEICAVSRISKKEI 190

Query: 201 AA----YVKAMEMSIGEAAKISRIRTTDDFVSRFCSY 233
                  +KA+E S+        + TT DF+SR   Y
Sbjct: 191 GRCFKLILKALETSVD-------LITTGDFMSRNWRY 220

gb|AAW44219.1| transcription initiation factor iib, putative [Cryptococcus neoformans var. neoformans JEC21]
ref|XP_571526.1| transcription initiation factor iib, putative [Cryptococcus neoformans var. neoformans JEC21]
(447 aa)

Score: 131 bits (330), Expect: 2.76593e-29
Length: 348, Idn/Pos/Gap = 99/171/47 (28%/49%/13%)

Query:   9 DVPDVCGECGST--DLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRV  66
           ++  +C  C +   ++VE+   GDLVCA CG +  + ++D   EWRTF  D++  DP+RV
Sbjct:  99 NIKQICPNCRTDPPNIVEEYAKGDLVCADCGTILGDRIVDTRSEWRTFAGDENGDDPSRV 158

Query:  67 GGSINPLLDSGLATSISQGPAGANALNERLARAQSRNVLDANDRY-------VTECYNRI 119
           G + NPLL S    ++     G   +   L RAQ+R    +N  Y       ++  ++RI
Sbjct: 159 GDAGNPLLGSNHLDTMISHKDGRTGIARDLNRAQARANTLSNGIYGKSSVAQLSAVFSRI 218

Query: 120 SYLCERSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRN 179
              C+   LP+ V++RA  + ++  +          ARA   ++E A +I+A +  ACR+
Sbjct: 219 GEKCDAMQLPRGVRERAQHVYKIVDE----------ARAIKGKNEPA-VIAACIVYACRD 267

Query: 180 EGFPRTFNEISVIVSVAKS---RVAAYVKAMEMSIGEAAKISRIRTTDD-------FVSR 229
               RTF E+   + ++K    +V  +VK++  S      +  +  +++        + R
Sbjct: 268 AKVHRTFQEVCKALKISKKELGQVFNHVKSVVQSSSAQGSMVSVHGSNNAQESAEGLLGR 327

Query: 230 FCSYLEIPNIVRSLVNQVARAAAEKDGIHGRTLVSIAAGAIYFV-LLLWRETCPQSIPAT 288
           F +YL++ N V ++   +A  A  K  I GR+ VSIAAG +YF  +LL + T  + I A 
Sbjct: 328 FANYLDLGNAVFNVSKHIAGEAVAKSAIDGRSPVSIAAGVLYFTCVLLGKSTTAKDISAM 387

Query: 289 LRVSDEALVNRIAEVSGITEGVVKTVASRIRQYRDRGLLPPDWVRRFP 336
             VS+             T+ + K VAS++       ++ P+W   +P
Sbjct: 388 GGVSEST-----------TKLITKMVASKLDD-----VIRPEWRTEYP 419

gb|EAL19948.1| hypothetical protein CNBF2750 [Cryptococcus neoformans var. neoformans B-3501A]
(371 aa)

Score: 130 bits (327), Expect: 7.10089e-29
Length: 348, Idn/Pos/Gap = 99/171/47 (28%/49%/13%)

Query:   9 DVPDVCGECGST--DLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRV  66
           ++  +C  C +   ++VE+   GDLVCA CG +  + ++D   EWRTF  D++  DP+RV
Sbjct:  23 NIKQICPNCRTDPPNIVEEYAKGDLVCADCGTILGDRIVDTRSEWRTFAGDENGDDPSRV  82

Query:  67 GGSINPLLDSGLATSISQGPAGANALNERLARAQSRNVLDANDRY-------VTECYNRI 119
           G + NPLL S    ++     G   +   L RAQ+R    +N  Y       ++  ++RI
Sbjct:  83 GDAGNPLLGSNHLDTMISHKDGRTGIARDLNRAQARANTLSNGIYGKSSVAQLSAVFSRI 142

Query: 120 SYLCERSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRN 179
              C+   LP+ V++RA  + ++  +          ARA   ++E A +I+A +  ACR+
Sbjct: 143 GEKCDAMQLPRGVRERAQHVYKIVDE----------ARAIKGKNEPA-VIAACIVYACRD 191

Query: 180 EGFPRTFNEISVIVSVAKS---RVAAYVKAMEMSIGEAAKISRIRTTDD-------FVSR 229
               RTF E+   + ++K    +V  +VK++  S      +  +  +++        + R
Sbjct: 192 AKVHRTFQEVCKALKISKKELGQVFNHVKSVVQSSSAQGSMVSVHGSNNAQESAEGLLGR 251

Query: 230 FCSYLEIPNIVRSLVNQVARAAAEKDGIHGRTLVSIAAGAIYFV-LLLWRETCPQSIPAT 288
           F +YL++ N V ++   +A  A  K  I GR+ VSIAAG +YF  +LL + T  + I A 
Sbjct: 252 FANYLDLGNAVFNVSKHIAGEAVAKSAIDGRSPVSIAAGVLYFTCVLLGKSTTAKDISAM 311

Query: 289 LRVSDEALVNRIAEVSGITEGVVKTVASRIRQYRDRGLLPPDWVRRFP 336
             VS+             T+ + K VAS++       ++ P+W   +P
Sbjct: 312 GGVSEST-----------TKLITKMVASKLDD-----VIRPEWRTEYP 343

gb|AAW44220.1| transcription initiation factor iib, putative [Cryptococcus neoformans var. neoformans JEC21]
ref|XP_571527.1| transcription initiation factor iib, putative [Cryptococcus neoformans var. neoformans JEC21]
(371 aa)

Score: 129 bits (325), Expect: 1.06874e-28
Length: 348, Idn/Pos/Gap = 99/171/47 (28%/49%/13%)

Query:   9 DVPDVCGECGST--DLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRV  66
           ++  +C  C +   ++VE+   GDLVCA CG +  + ++D   EWRTF  D++  DP+RV
Sbjct:  23 NIKQICPNCRTDPPNIVEEYAKGDLVCADCGTILGDRIVDTRSEWRTFAGDENGDDPSRV  82

Query:  67 GGSINPLLDSGLATSISQGPAGANALNERLARAQSRNVLDANDRY-------VTECYNRI 119
           G + NPLL S    ++     G   +   L RAQ+R    +N  Y       ++  ++RI
Sbjct:  83 GDAGNPLLGSNHLDTMISHKDGRTGIARDLNRAQARANTLSNGIYGKSSVAQLSAVFSRI 142

Query: 120 SYLCERSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRN 179
              C+   LP+ V++RA  + ++  +          ARA   ++E A +I+A +  ACR+
Sbjct: 143 GEKCDAMQLPRGVRERAQHVYKIVDE----------ARAIKGKNEPA-VIAACIVYACRD 191

Query: 180 EGFPRTFNEISVIVSVAKS---RVAAYVKAMEMSIGEAAKISRIRTTDD-------FVSR 229
               RTF E+   + ++K    +V  +VK++  S      +  +  +++        + R
Sbjct: 192 AKVHRTFQEVCKALKISKKELGQVFNHVKSVVQSSSAQGSMVSVHGSNNAQESAEGLLGR 251

Query: 230 FCSYLEIPNIVRSLVNQVARAAAEKDGIHGRTLVSIAAGAIYFV-LLLWRETCPQSIPAT 288
           F +YL++ N V ++   +A  A  K  I GR+ VSIAAG +YF  +LL + T  + I A 
Sbjct: 252 FANYLDLGNAVFNVSKHIAGEAVAKSAIDGRSPVSIAAGVLYFTCVLLGKSTTAKDISAM 311

Query: 289 LRVSDEALVNRIAEVSGITEGVVKTVASRIRQYRDRGLLPPDWVRRFP 336
             VS+             T+ + K VAS++       ++ P+W   +P
Sbjct: 312 GGVSEST-----------TKLITKMVASKLDD-----VIRPEWRTEYP 343

gb|AAT12348.1| transcription initiation factor TFIIB [Antonospora locustae]
(306 aa)

Score: 128 bits (321), Expect: 3.49485e-28
Length: 312, Idn/Pos/Gap = 93/155/23 (29%/49%/7%)

Query:  14 CGECG-STDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSINP  72
           C +CG S +++ED K G  VC+ CG V    +ID G EWR F +D +A + +RVG + NP
Sbjct:   8 CKDCGESRNIIEDYKAGYNVCSNCGCVIGNRIIDEGSEWRNF-SDANAPNLSRVGSANNP  66

Query:  73 LLDSGLATSISQGPAGANALNERLARAQSRNVLDANDRYVTECYNRISYLCERSGLPQLV 132
           LLD+    +I      +  +N  L++ Q R+ +   ++ +   +N IS LC+R+ + + +
Sbjct:  67 LLDAETYDTIISTERSSFGVN--LSKTQMRSSMRGPEQALINGFNLISALCDRANMTKTI 124

Query: 133 KDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRTFNEISVI 192
            DRA                 V  +   +       ++A ++IACR EG PRTF EISV+
Sbjct: 125 CDRA-----------KFNFKAVEEKKIAKSKSHKGTVAACIYIACRQEGCPRTFKEISVL 173

Query: 193 VSVAKSRVAAYVKAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPNIVRSLVNQVARAAA 252
            +V +  +    K +   + +   +S      D VSRFCS L++ +    L   +A+   
Sbjct: 174 TAVPRKDIGRAYKIIYPHLEKFVAVS----VKDIVSRFCSNLDLGHDAEKLAVAIAQNVQ 229

Query: 253 EKDGIHGRTLVSIAAGAIYFVLLLWRE--TCPQSIPATLRVSDEALVNRIAEVSGITEGV 310
             D + G++  SIAA  +Y V  ++ +  +  + +  T  V+D  + N   E+    E V
Sbjct: 230 RLDILTGKSTDSIAAAIVYLVTNVFSQHKSMQKFLQNTSNVTDVTIKNVYKELVLHKEEV 289

Query: 311 VKTVASRIRQYR 322
           + + A  I QYR
Sbjct: 290 IPSEA--ISQYR 299

gb|AAB09756.1| transcription factor TFIIB [Glycine max]
sp|P48513|TF2B_SOYBN Transcription initiation factor IIB (General transcription factor TFIIB)
pir||T06440 probable transcription initiation factor TFIIB - soybean
(313 aa)

Score: 128 bits (321), Expect: 3.58344e-28
Length: 308, Idn/Pos/Gap = 100/151/39 (32%/49%/12%)

Query:  14 CGECG-STDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSINP  72
           C +C   T++V D   GD VC++CG+V     ID   EWRTF N+    DPNRVGG  NP
Sbjct:   6 CSDCKRQTEVVFDHSAGDTVCSECGLVLESHSIDETSEWRTFANESGDNDPNRVGGPSNP  65

Query:  73 LL-DSGLATSISQ--GPAGANALNERLARAQSRNVLDANDRYVTECYNRISYLCERSGLP 129
           LL D GL+T I++  G  G   L+  L R Q+R      DR + + +  I+ + +R GL 
Sbjct:  66 LLTDGGLSTVIAKPNGGGGGEFLSSSLGRWQNRG--SNPDRALIQAFKTIATMSDRLGLV 123

Query: 130 QLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRTFNEI 189
             +KDRA E+ +   D  +       +R R ++    ++++A L+IACR E  PRT  EI
Sbjct: 124 ATIKDRANEIYKRVEDQKS-------SRGRNQD----ALLAACLYIACRQEDKPRTVKEI 172

Query: 190 SVIVSVAKS----RVAAY-VKAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPNIVRSLV 244
             + + A      R   Y VK + +  G A ++  I    DF+ RFCS L + N      
Sbjct: 173 CSVANGATKKEIGRAKEYIVKQLGLENGNAVEMGTIH-AGDFMRRFCSNLCMNNQAVKAA 231

Query: 245 NQVARAAAEKDGIHGRTLVSIAAGAIYFVLLLWRETCPQSIPATLRVSDEALVNRIAEVS 304
            +  + + E D    R+ +SIAA  IY +  L                D+  +  I+  +
Sbjct: 232 QEAVQKSEEFD--IRRSPISIAAAVIYIITQL--------------SDDKKPLKDISLAT 275

Query: 305 GITEGVVK 312
           G+ EG ++
Sbjct: 276 GVAEGTIR 283

gb|AAL73491.1| general transcription factor TFIIB [Oryza sativa]
dbj|BAD33339.1| Transcription initiation factor IIB [Oryza sativa (japonica cultivar-group)]
dbj|BAD34211.1| Transcription initiation factor IIB [Oryza sativa (japonica cultivar-group)]
sp|Q8W0W3|TF2B_ORYSA Transcription initiation factor IIB (General transcription factor TFIIB)
(312 aa)

Score: 124 bits (312), Expect: 3.67533e-27
Length: 329, Idn/Pos/Gap = 102/157/41 (31%/47%/12%)

Query:  14 CGECGS-TDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSINP  72
           C +C   T++  D   GD VC +CG+V     +D   EWRTF N+ S  DP RVGG  NP
Sbjct:   6 CPDCKKHTEVAFDHSAGDTVCTECGLVLEAHSVDETSEWRTFANESSDNDPVRVGGPTNP  65

Query:  73 LL-DSGLATSISQGPAGANA--LNERLARAQSRNVLDANDRYVTECYNRISYLCERSGLP 129
           LL D GL+T I++ P GA    L+  L R Q+R      DR +   +  I+ + +R GL 
Sbjct:  66 LLTDGGLSTVIAK-PNGAQGEFLSSSLGRWQNRG--SNPDRSLILAFRTIANMADRLGLV 122

Query: 130 QLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRTFNEI 189
             +KDRA E+ +   D        +R R +       +I++A L+IACR E  PRT  EI
Sbjct: 123 ATIKDRANEIYKKVED-----LKSIRGRNQ------DAILAACLYIACRQEDRPRTVKEI 171

Query: 190 SVIVSVAKSRVAA-----YVKAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPNIVRSLV 244
             + + A  +         VK +E+ +G++ ++  I    DF+ RFCS L + N      
Sbjct: 172 CSVANGATKKEIGRAKEFIVKQLEVEMGQSMEMGTIH-AGDFLRRFCSTLGMNNQAVKAA 230

Query: 245 NQVARAAAEKDGIHGRTLVSIAAGAIYFVLLLWRETCPQSIPATLRVSDEALVNRIAEVS 304
            +  + + E D    R+ +SIAA  IY +  L                D+  +  I+  +
Sbjct: 231 QEAVQRSEELD--IRRSPISIAAAVIYMITQL--------------SDDKKPLKDISLAT 274

Query: 305 GITEGVVKTVASRIRQYRDRGLLPPDWVR 333
           G+ EG ++     +  Y  R L+P  + +
Sbjct: 275 GVAEGTIRNSYKDLYPYASR-LIPNTYAK 302

gb|AAR28003.1| TFIIB2 [Arabidopsis thaliana]
gb|AAF02810.1| transcription initiation factor IIB (TFIIB) [Arabidopsis thaliana]
gb|AAM65403.1| transcription initiation factor IIB (TFIIB) [Arabidopsis thaliana]
gb|AAL31139.1| AT3g10330/F14P13_7 [Arabidopsis thaliana]
gb|AAK91437.1| AT3g10330/F14P13_7 [Arabidopsis thaliana]
sp|Q9SS44|TF2B2_ARATH Transcription initiation factor IIB-2 (General transcription factor TFIIB-2) (AtTFIIB2)
ref|NP_187644.1| transcription initiation factor IIB-2 / general transcription factor TFIIB-2 (TFIIB2) [Arabidopsis thaliana]
(312 aa)

Score: 122 bits (307), Expect: 1.22208e-26
Length: 308, Idn/Pos/Gap = 100/150/40 (32%/48%/12%)

Query:  14 CGECGS-TDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSINP  72
           C +C   T++V D   GD VC++CG+V     ID   EWRTF N+    DP RVGG  NP
Sbjct:   6 CSDCKRHTEVVFDHSAGDTVCSECGLVLESHSIDETSEWRTFANESGDNDPVRVGGPTNP  65

Query:  73 LL-DSGLATSISQGPAGANA--LNERLARAQSRNVLDANDRYVTECYNRISYLCERSGLP 129
           LL D GL T IS+ P G++   L+  L R Q+R      DR +   +  I+ + +R GL 
Sbjct:  66 LLADGGLTTVISK-PNGSSGDFLSSSLGRWQNRG--SNPDRGLIVAFKTIATMADRLGLV 122

Query: 130 QLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRTFNEI 189
             +KDRA E+ +   D  +       +R R ++    ++++A L+IACR E  PRT  EI
Sbjct: 123 ATIKDRANEIYKRVEDQKS-------SRGRNQD----ALLAACLYIACRQEDKPRTVKEI 171

Query: 190 SVIVSVAKS----RVAAY-VKAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPNIVRSLV 244
             + + A      R   Y VK + +  G+  ++  I    DF+ RFCS L + N      
Sbjct: 172 CSVANGATKKEIGRAKEYIVKQLGLETGQLVEMGTIH-AGDFMRRFCSNLGMTNQTVKAA 230

Query: 245 NQVARAAAEKDGIHGRTLVSIAAGAIYFVLLLWRETCPQSIPATLRVSDEALVNRIAEVS 304
            +  + + E D    R+ +SIAA  IY +  L  E  P              +  I+  +
Sbjct: 231 QESVQKSEEFD--IRRSPISIAAAVIYIITQLSDEKKP--------------LRDISVAT 274

Query: 305 GITEGVVK 312
           G+ EG ++
Sbjct: 275 GVAEGTIR 282

sp|Q9NHP7|TF2B_DROVI Transcription initiation factor IIB (General transcription factor TFIIB)
gb|AAF71709.1| transcription factor TFIIB [Drosophila virilis]
(293 aa)

Score: 122 bits (307), Expect: 1.31739e-26
Length: 255, Idn/Pos/Gap = 80/125/45 (31%/49%/17%)

Query:  22 LVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSINPLLDSG-LAT  80
           L+ED + GD++C++CG+V  +                        GG  NPLL  G L+T
Sbjct:  22 LIEDYRAGDMICSECGLVVGDAF----------------------GGPENPLLSGGHLST  59

Query:  81 SISQGPAGANALNERLARAQSRNVLDANDRYVTECYNRISYLCERSGLPQLVKDRACELL 140
            I  G   A+       +  +R  + ++DR +   +  IS + +R  LP+ + DRA  L 
Sbjct:  60 IIGPGTGSASFDAFGAPKYPNRRTMRSSDRSLISAFKEISSMADRINLPKTIVDRANTLF 119

Query: 141 RLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRTFNEISVIVSVAKSRV 200
           +  +D   L      A+A           SA L+IACR EG PRTF EI  +  ++K  +
Sbjct: 120 KQVHDGKNLKGRSNDAKA-----------SACLYIACRQEGVPRTFKEICAVSKISKKEI 168

Query: 201 AA----YVKAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPNIVRSLVNQVARAAAEKDG 256
                  +KA+E S+        + TT DF+ RFC+ L++PN+V+     +A+ A E D 
Sbjct: 169 GRCFKLTLKALETSVD-------LITTADFMCRFCANLDLPNMVQRAATHIAKKAVEMDI 221

Query: 257 IHGRTLVSIAAGAIY 271
           + GR+ +S+AA AIY
Sbjct: 222 VPGRSPISVAAAAIY 236

emb|CAA84309.1| AtTFIIB2 [Arabidopsis thaliana]
(301 aa)

Score: 121 bits (303), Expect: 4.0976e-26
Length: 301, Idn/Pos/Gap = 98/147/39 (32%/48%/12%)

Query:  20 TDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSINPLL-DSGL  78
           T++V D   GD VC++CG+V     ID   EWRTF N+    DP RVGG  NPLL D GL
Sbjct:   2 TEVVFDHSAGDTVCSECGLVLESHSIDETSEWRTFANESGDNDPVRVGGPTNPLLADGGL  61

Query:  79 ATSISQGPAGANA--LNERLARAQSRNVLDANDRYVTECYNRISYLCERSGLPQLVKDRA 136
            T IS+ P G++   L+  L R Q+R      DR +   +  I+ + +R GL   +KDRA
Sbjct:  62 TTVISK-PNGSSGDFLSSSLGRWQNRG--SNPDRGLIVAFKTIATMADRLGLVATIKDRA 118

Query: 137 CELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRTFNEISVIVSVA 196
            E+ +   D  +       +R R ++    ++++A L+IACR E  PRT  EI  + + A
Sbjct: 119 NEIYKRVEDQKS-------SRGRNQD----ALLAACLYIACRQEDKPRTVKEICSVANGA 167

Query: 197 KS----RVAAY-VKAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPNIVRSLVNQVARAA 251
                 R   Y VK + +  G+  ++  I    DF+ RFCS L + N       +  + +
Sbjct: 168 TKKEIGRAKEYIVKQLGLETGQLVEMGTIH-AGDFMRRFCSNLGMTNQTVKAAQESVQKS 226

Query: 252 AEKDGIHGRTLVSIAAGAIYFVLLLWRETCPQSIPATLRVSDEALVNRIAEVSGITEGVV 311
            E D    R+ +SIAA  IY +  L  E  P              +  I+  +G+ EG +
Sbjct: 227 EEFD--IRRSPISIAAAVIYIITQLSDEKKP--------------LRDISVATGVAEGTI 270

Query: 312 K 312
           +
Sbjct: 271 R 271

gb|EAA69258.1| hypothetical protein FG00597.1 [Gibberella zeae PH-1]
ref|XP_380773.1| hypothetical protein FG00597.1 [Gibberella zeae PH-1]
(348 aa)

Score: 120 bits (302), Expect: 4.76163e-26
Length: 368, Idn/Pos/Gap = 99/174/56 (26%/47%/15%)

Query:   5 TMERDVPDV--CGECG--STDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSA  60
           T + D+ +V  C EC     +LV++  +GD VC+ CG+V    +ID   EWRTF NDD  
Sbjct:  11 TFQEDLSNVLVCPECNINPPNLVDEWSSGDTVCSDCGLVVGSRIIDTRSEWRTFANDDQG  70

Query:  61 Y-DPNRVGGSINPLLD-SGLATSISQGPAGANALNERLARAQSRNVLDANDRYVTECYNR 118
             DP+RVGG  +  ++   LAT+++     A   ++ L+R Q+    D   + +   Y  
Sbjct:  71 GDDPSRVGGPQDEFVEGQQLATTVAFSDLKA---HKALSRTQNNTTQDKAQKGLMLAYKE 127

Query: 119 ISYLCERSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACR 178
           I  LCE   + Q V + A  + +L   H  L           +     ++I+  +FIACR
Sbjct: 128 IVSLCEAINMGQNVSNAAKHIFKLVDKHKFL-----------KGKPQEAVIAGCIFIACR 176

Query: 179 NEGFPRTFNEISVIVSVAKSRVA-------AYVKAMEMSIGEAAKISRIRT-------TD 224
               PRTF EI  + SV+K  V        ++++ ++ + G+A  ++ +          +
Sbjct: 177 QNNVPRTFREIFNLTSVSKKEVGRVFKQLQSFLQKLQETEGDATGLNTVTNYENTSVGAE 236

Query: 225 DFVSRFCSYLEIPNIVRSLVNQVARAAAEK----DGIHGRTLVSIAAGAIYFVLLLWRET 280
           D   R+ S L + N  +  V +++R  AE+      + GR+ +S+AA  I+    +  E 
Sbjct: 237 DLCGRYVSQLGLLN--QQKVAKISRDLAEQANDIKDLAGRSPLSVAAACIFMACHVVGEA 294

Query: 281 CPQSIPATLRVSDEALVNRIAEVSGITEGVVKTVASRIRQYRDRGLLPPDWVRRFPSRLE 340
           CP  +              IA+ +G+++G VKT    +   R + L+  +W+    + +E
Sbjct: 295 CPSHL--------------IAKQAGVSDGTVKTAYKYLYAAR-KQLIKKEWLVDNGTSME 339

Query: 341 PELPTSSS 348
             LP +++
Sbjct: 340 -SLPQANA 346

ref|XP_327575.1| hypothetical protein [Neurospora crassa]
gb|EAA32907.1| hypothetical protein [Neurospora crassa]
(348 aa)

Score: 120 bits (302), Expect: 5.21934e-26
Length: 340, Idn/Pos/Gap = 107/152/58 (31%/44%/17%)

Query:  13 VCGECGST--DLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAY-DPNRVGGS  69
           +C EC      LVE+  +GD+VC  CG+V  E +ID   EWRTF NDD    DP+RVG  
Sbjct:  24 MCPECKEDPPHLVEEFSSGDMVCGSCGLVLGERIIDTRSEWRTFSNDDQGNDDPSRVGDG  83

Query:  70 INPLLDSG-LATSIS-QGPAGANALNERLARAQSRNVLDANDRYVTECYNRISYLCERSG 127
            N L+D   L T+I+  G  G N     L+  Q++   D N + + + Y  I  L +   
Sbjct:  84 PNQLIDGDQLQTTIAFDGKNGKN-----LSHLQNKITQDKNSKQLMQAYRDIQGLTDSIN 138

Query: 128 LPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRTFN 187
               V + A  + +L  D+  L      A           I +  +FIACR  G PRTF 
Sbjct: 139 AGTQVANAAKHIYKLVEDNKALKGKSQEA-----------ITAGCIFIACRQTGVPRTFR 187

Query: 188 EISVIVSVAKSRVAAYVKAME---MSIG--EAAKISRI------------RTTDDFVSRF 230
           EI  +  V+K  +    K +E     IG  E A  + I             T  +  +R+
Sbjct: 188 EIYSLTKVSKKEIGRVFKQLESFLQKIGGEEHAITTSIPTFNQQYQGKGSTTATELCARY 247

Query: 231 CSYLEIPNIVRSLVNQVARAAAEKDG----IHGRTLVSIAAGAIYFVLLLWRETCPQSIP 286
           CS L   N V   V  VAR  A+K      + GR+ +S+AA  IY    +  E+      
Sbjct: 248 CSNLNFRNSVA--VEDVARQLADKTSTISELAGRSPLSVAAACIYMASHIRNES------ 299

Query: 287 ATLRVSDEALVNRIAEVSGITEGVVKTVASRIRQYRDRGL 326
              R S E     IA V+G+++G VKT    +   +D+ L
Sbjct: 300 ---RTSKE-----IATVAGVSDGTVKTAYRLLYNKKDKLL 331

gb|EAA61006.1| hypothetical protein AN4928.2 [Aspergillus nidulans FGSC A4]
ref|XP_409065.1| hypothetical protein AN4928.2 [Aspergillus nidulans FGSC A4]
(351 aa)

Score: 119 bits (299), Expect: 1.18231e-25
Length: 344, Idn/Pos/Gap = 98/158/52 (28%/45%/15%)

Query:  13 VCGECGSTDL-VEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAY-DPNRVGGSI  70
           +C EC      +E   + + VC  CG+V A+  ID+  EWRTF NDD    DP+RVG + 
Sbjct:  25 ICPECKEMPPNLEFPGSHETVCGSCGLVLADREIDMHSEWRTFSNDDQNNDDPSRVGDAT  84

Query:  71 NPLLDSG-LATSISQGPAGANALNERLARAQSRNVLDANDRYVTECYNRISYLCERSGLP 129
           NPLL+   L T I+ G +G       L RAQ++   D  ++ +   Y  I  LC+  G+P
Sbjct:  85 NPLLNGDQLETQIASGGSGR---VRDLYRAQNKQSSDKANKSLLAAYKEIGALCDGFGIP 141

Query: 130 QLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRTFNEI 189
           + V D A  L ++  D          A+A F+      II+  +FIACR    PRTF EI
Sbjct: 142 KNVADTAKYLFKIVDD----------AKA-FKGKSQDVIIAGCIFIACRKCKVPRTFTEI 190

Query: 190 SVIVSVAKSRVAAYVKAME--------------MSIGEAAKISRIRTT------DDFVSR 229
             +  V++  +    KA+E              +S G     +   T        D  SR
Sbjct: 191 FAVTKVSRKEIGRIYKALEKFFTSQNLERANAVVSNGGVPDPNDTYTATTSTKPSDLCSR 250

Query: 230 FCSYLEIPNIVRSLVNQVARAAAEKDGIHGRTLVSIAAGAIYFVLLLWRETCPQSIPATL 289
           FC+ L++P  V S+ + ++     +  + GR+ +SI A  IY    L     P+S     
Sbjct: 251 FCNLLDLPFQVTSVSSALSDRVTTEGNLAGRSPLSIVAACIYMASYLMGH--PKS----- 303

Query: 290 RVSDEALVNRIAEVSGITEGVVKTVASRIRQYRDRGLLPPDWVR 333
                     I++V+ +++G ++    ++   R+  L+  +W++
Sbjct: 304 -------AKEISQVAHVSDGTIRGAYKQLYTERE-SLVDKEWIK 339

gb|EAK90894.1| likely transcription factor TFIIB [Candida albicans SC5314]
(346 aa)

Score: 117 bits (293), Expect: 5.86776e-25
Length: 342, Idn/Pos/Gap = 92/156/45 (26%/45%/13%)

Query:   9 DVPDVCGECGS--TDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDD-SAYDPNR  65
           +V  +C +C     DL+E    GD++C QCG+V ++ ++D   EWRTF+NDD +  DP+R
Sbjct:  17 NVTLICPDCKQFPPDLIERFSEGDIICGQCGLVLSDRIVDTRSEWRTFQNDDKNTDDPSR  76

Query:  66 VGGSINPLLDS-GLATSISQGP-AGANALNERLARAQSRNVLDANDRYVTECYNRISYLC 123
           VG + N L D+  L T IS  P + + +    L + Q ++++D  +  +   Y +IS LC
Sbjct:  77 VGDASNSLYDTEDLTTMISYAPNSNSGSSKNSLNKIQQKSLVDKKNYALQTAYQKISELC 136

Query: 124 ERSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFP 183
               LP+   D A  L +            VR     +     SI++A + + CR    P
Sbjct: 137 NGYQLPKSASDAAKHLYK-----------AVREDRLLKGKTQDSIMAATILLGCRRADVP 185

Query: 184 RTFNEISVIVSVAKSRVAAYVKAME-------------MSIGEAAKISRIRTTDDFVSRF 230
           RT  EI  + +V   ++A     ++              SI +        + +D + RF
Sbjct: 186 RTLEEIRALTNVPTKQIAKVTGLIKKIIRSHLNNDDASTSIVDETSSLTTHSAEDLIRRF 245

Query: 231 CSYLEIPNIVRSLVNQVARAAAEKDGIHGRTLVSIAAGAIYFVLLLWRETCPQSIPATLR 290
           CS+L +   + S    VAR   +   + GR+  +IAA +I+               A   
Sbjct: 246 CSHLGLSLAITSASEYVARKCHDLGVLAGRSPTTIAATSIFL--------------AAKS 291

Query: 291 VSDEALV-NRIAEVSGITEGVVKTVASRIRQYRDRGLLPPDW 331
           + D  L   +I + +G++ G +K  + +I Q   + L+ P W
Sbjct: 292 LGDTKLTQQQIRDKTGVSIGTIKN-SYKILQENAKDLIDPAW 332

gb|EAK86249.1| hypothetical protein UM04794.1 [Ustilago maydis 521]
ref|XP_402409.1| hypothetical protein UM04794.1 [Ustilago maydis 521]
(375 aa)

Score: 113 bits (282), Expect: 1.01803e-23
Length: 359, Idn/Pos/Gap = 108/164/62 (30%/45%/17%)

Query:   3 APTMERD-VPD-----VCGECGST--DLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTF  54
           AP  E D VPD     +C +C +   +L E+ ++GDLVCA CG+V  E +ID   EWRTF
Sbjct:  30 APKGEDDFVPDLNVRLICRDCKTDPPNLAEEFESGDLVCADCGLVVGENIIDTRSEWRTF  89

Query:  55 ENDDSAYDPNRVGGSINPLLD---SGLATSISQGPAGANALNERLARAQSRNVLDANDRY 111
            N+D   DP+RVG + NPLLD     L + I     G  A +  L R  +R      DR 
Sbjct:  90 ANEDGD-DPSRVGAASNPLLDGINEQLESRIGYRDGGTGA-SRDLQRTMNR-ATGTRDRN 146

Query: 112 VTECYNRISYLCERSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISA 171
           + + +  I   C+   LP+ V D A +  R            V      R  +  +II+A
Sbjct: 147 MLDAFEDIQRKCDSIHLPRTVSDVAKQAYRR-----------VEEEKILRGKKPDAIIAA 195

Query: 172 ALFIACRNEGFPRTFNEISVIVSVAKSRVAAYVKAMEMSIGEAAKI------SRIRTTD- 224
           A+++AC+    PRTF EI  + SV+K  +    K M+ + G  A        SR    + 
Sbjct: 196 AIYVACKMNHVPRTFPEICSLTSVSKKHIGQCFKEMQQAFGLNATGTGSVDGSRASANNS 255

Query: 225 --------------DFVSRFCSYLEIP-NIVRSLVNQVARAAAEKDGIHGRTLVSIAAGA 269
                         D V R+C++L +   I RS  +  AR   E   + GR+ ++IAA  
Sbjct: 256 GTSTPIGIGPTGAADLVGRYCNHLGLEMRITRSTEDITARVR-ELGILAGRSPITIAAAC 314

Query: 270 IYFVLLLWRETCPQSIPATLRVSDEALVNRIAEVSGITEGVVKTVASRIRQYRDRGLLP 328
           IYF  LLW                +    RI++ +G+++  +K     + +++D+   P
Sbjct: 315 IYFSTLLW--------------GVDKGAKRISQAAGVSDVTIKNSFKELLKHKDKIATP 359

gb|EAA05855.2| ENSANGP00000020018 [Anopheles gambiae str. PEST]
ref|XP_310127.2| ENSANGP00000020018 [Anopheles gambiae str. PEST]
(344 aa)

Score: 109 bits (273), Expect: 1.27563e-22
Length: 241, Idn/Pos/Gap = 76/119/21 (31%/49%/8%)

Query:  31 LVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSINPLLDSGLATSISQGPAGAN  90
           ++C+ CG++  + +ID   EWRTF +D S  DP+RV GS +P+L + L+T I     G  
Sbjct:   1 MICSDCGLIVGDRMIDPSSEWRTFSDDPSRPDPSRV-GSTDPVLQN-LSTFIQPSANGFE  58

Query:  91 ALNERLARAQSRNVLDANDRYVTECYNRISYLCERSGLPQLVKDRACELLRLYYDHLTLG 150
             N       S   +D   R +   +  I+ + ER   P  +   A  + +   +   L 
Sbjct:  59 PPNHF-----SFLKMDTTTRKLMFGFAMIATMAERINAPASIVSHAKTIFKQALEPAAL- 112

Query: 151 ADGVRARARFREDETASIISAALFIACRNEGFPRTFNEISVIVSVAKSRVAAYVKAMEMS 210
                     R  E  S+  A L+IACR EG PRTF E+  + S +K  +    K +   
Sbjct: 113 --------THRSLEAVSV--ACLYIACRQEGVPRTFKEMCAVCSASKKEIGRCFKLITKV 162

Query: 211 IGEAAKISRIRTTDDFVSRFCSYLEIPNIVRSLVNQVARAAAEKDGIHGRTLVSIAAGAI 270
           +  A  +  I T++DF+ RFCS L +P+ V+     +A+ A E D +  R+ +S+AA AI
Sbjct: 163 L--ATSLDHI-TSEDFMQRFCSKLFLPHEVQKAATHIAQKAFEADLVPDRSPISVAAAAI 219

Query: 271 Y 271
           Y
Sbjct: 220 Y 220

ref|NP_394398.1| transcription initiation factor IIB related protein [Thermoplasma acidophilum DSM 1728]
emb|CAC12069.1| transcription initiation factor IIB related protein [Thermoplasma acidophilum]
sp|Q9HJM7|TF2B1_THEAC Transcription initiation factor IIB 1 (TFIIB 1)
(312 aa)

Score: 105 bits (263), Expect: 1.55889e-21
Length: 324, Idn/Pos/Gap = 85/145/40 (26%/44%/12%)

Query:   1 MSAPTMERDVPDV--CGECGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDD  58
           M   T ++ V ++  C ECGST+L+ D ++G+LVC +CG V  +  ID G EWR F+++ 
Sbjct:   1 MVENTKKKKVEEIERCPECGSTNLIRDYEHGELVCGECGAVIEDAYIDQGPEWRAFDSEQ  60

Query:  59 SAYDPNRVGGSINPLLDSGLATSISQG---------PAGANALNERLARAQSR-NVLDAN 108
           +             + D GL+T IS           P    A   RL + Q R  V +A 
Sbjct:  61 NESRARAGSPMTYTIHDKGLSTDISWKNKDSYGRSIPTRNRAQLYRLRKWQKRIKVSNAA 120

Query: 109 DRYVTECYNRISYLCERSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASI 168
           +R +++    +  +     +P  VK+ A  + R       +  + +R R+         +
Sbjct: 121 ERNLSQALQELERMASNLSIPDDVKETAAVIYR-----KAVKQNMIRGRS------IEGV 169

Query: 169 ISAALFIACRNEGFPRTFNEISVIVSVAKSRVAAYVKAMEMSIGEAAKISRIRTTDDFVS 228
           ++ AL+ ACR    PRT  EI+ +  V K  +    + M   +      S+    +D++S
Sbjct: 170 VAGALYAACRITNVPRTLGEIASVTRVKKKEIGRTYRIMSRYLKLNIMPSK---AEDYIS 226

Query: 229 RFCSYLEIPNIVRSLVNQVARAAAEKDGIHGRTLVSIAAGAIYFVLLLWRETCPQSIPAT 288
           RFCS L++    R+   ++ R+A       G+    +AA AIY               A+
Sbjct: 227 RFCSKLKLSMDTRNKALEILRSAENAGLTSGKGPTGVAAAAIYI--------------AS 272

Query: 289 LRVSDEALVNRIAEVSGITEGVVK 312
           L   +      +AEV+G+TE  ++
Sbjct: 273 LMTGERRTQRAVAEVAGVTEVTIR 296

gb|EAA54578.1| hypothetical protein MG05370.4 [Magnaporthe grisea 70-15]
ref|XP_359995.1| hypothetical protein MG05370.4 [Magnaporthe grisea 70-15]
(371 aa)

Score: 105 bits (262), Expect: 2.48737e-21
Length: 345, Idn/Pos/Gap = 91/157/86 (26%/45%/24%)

Query:  14 CGECG-STDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSINP  72
           C +CG  T L E+  +GD+VC +CG+V    ++D+G EWRTF ND++  DP+RVG + N 
Sbjct:  24 CNDCGVPTLLQEEVSSGDIVCTECGLVVGARIVDMGSEWRTFANDEAGDDPSRVGDAGNE  83

Query:  73 LLD-SGLATSI----SQGPA-----GANALNERLARAQSRNVLDANDRYVTECYNRISYL 122
           +   S L T +     QG +       NA N+++   + +  ++A    + +  ++I   
Sbjct:  84 IYGPSALETKVDMRRDQGASYKIMKSLNAANKKIQNEKGQAAINAGMAKIKDLVDKI--- 140

Query: 123 CERSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETA---------SIISAAL 173
               G   ++K                     +A++ FRE E A         + ++  +
Sbjct: 141 ---HGGGNVIK---------------------QAQSLFREVEEAKALKGKSADAAVAGCI 176

Query: 174 FIACRNEGFPRTFNEISVIVSVAKSRVAAYVKAMEMSI--------GEAAKI-------- 217
           FIACR E  PRTF EI  + +V+K  +    KA+E  +        G AA +        
Sbjct: 177 FIACRMEKVPRTFREIHALTNVSKKEIGRTYKALEEYVKKVNYENRGGAAAVDHKMPTAD 236

Query: 218 -------SRIRTTDDFVSRFCSYL--EIPNIVRSLVNQVARAAAEKDGIHGRTLVSIAAG 268
                  ++  T +   +R+CS L   + ++   +   +AR ++    + GR+ +S+AA 
Sbjct: 237 DDDDDMATKGTTAESLCTRYCSILGFRVSHLAERVAMHLARKSSSVADLAGRSPLSVAAA 296

Query: 269 AIYFVLLLWRETCPQSIPATLRVSDEALVNRIAEVSGITEGVVKT 313
            IY +  L  E          R S +     IA V+G+++G +KT
Sbjct: 297 CIYMMSHLIGEP---------RTSKD-----IAVVAGVSDGTIKT 327

ref|ZP_00307444.1| COG1405: Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB [Ferroplasma acidarmanus]
(311 aa)

Score: 103 bits (258), Expect: 6.2279e-21
Length: 311, Idn/Pos/Gap = 83/138/38 (26%/44%/12%)

Query:  12 DVCGECGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSIN  71
           D C ECGS+ LV D + G+LVC+ CG+V  +  ID G EWR F+++ S            
Sbjct:  13 DKCPECGSSQLVRDYERGELVCSNCGLVIDDSYIDEGPEWRAFDSEQSESRARTGSPMTY  72

Query:  72 PLLDSGLATSISQG---------PAGANALNERLARAQSR-NVLDANDRYVTECYNRISY 121
            + D GL+T IS           P    A   RL + Q R  V +A +R +++    +  
Sbjct:  73 TIHDKGLSTDISWKNKDSYGKSIPTRNRAQLYRLRKWQKRIKVSNAAERNLSQALQELER 132

Query: 122 LCERSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEG 181
           +     +P  V++ +  + R       +  + +R R+         +++ +++ ACR   
Sbjct: 133 MASNLSIPNDVRETSAVIYR-----KAVKQNMIRGRS------IEGVVAGSIYAACRITN 181

Query: 182 FPRTFNEISVIVSVAKSRVAAYVKAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPNIVR 241
            PRT +EI+ +  V K  +    + M   +      S+    DD+V+RFCS L +    R
Sbjct: 182 VPRTLDEIASVTRVKKKEIGRTYRIMARYLKLNILPSK---PDDYVNRFCSKLRLSMEAR 238

Query: 242 SLVNQVARAAAEKDGIHGRTLVSIAAGAIYFVLLLWRETCPQSIPATLRVSDEALVNRIA 301
               ++ + A + D   G+    +AA AIY   L+  E   Q                IA
Sbjct: 239 KRAEEILKMAIDNDLTSGKGPTGVAAAAIYIASLITGERRTQ--------------RAIA 284

Query: 302 EVSGITEGVVK 312
           EV+G+TE  ++
Sbjct: 285 EVAGVTEVTIR 295

ref|NP_143345.1| transcription initiation factor IIB [Pyrococcus horikoshii OT3]
dbj|BAA30589.1| 300aa long hypothetical transcription initiation factor IIB [Pyrococcus horikoshii OT3]
sp|O59151|TF2B_PYRHO Transcription initiation factor IIB (TFIIB)
(300 aa)

Score: 102 bits (254), Expect: 2.10569e-20
Length: 297, Idn/Pos/Gap = 87/141/19 (29%/47%/6%)

Query:  13 VCGECGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSINP  72
           VC  CGST+ + D + G++VCA+CG V  E +ID+G EWR F+        +R G   + 
Sbjct:   6 VCPVCGSTEFIYDPERGEIVCARCGYVIEENIIDMGPEWRAFDASQRE-KRSRTGAPESI  64

Query:  73 LL-DSGLATSISQGPAGANALNE---RLARAQSR-NVLDANDRYVTECYNRISYLCERSG 127
           LL D GL+T I    +    + E   RL + QSR  V DA +R +    + +  +  +  
Sbjct:  65 LLHDKGLSTDIGIDRSLTGLMREKMYRLRKWQSRLRVSDAAERNLAFALSELDRITAQLK 124

Query: 128 LPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRTFN 187
           LP+ V++ A  L R          + VR +   R     S+I+A ++ ACR    PRT +
Sbjct: 125 LPKHVEEEAARLYR----------EAVR-KGLIRGRSIESVIAACVYAACRLLKVPRTLD 173

Query: 188 EISVIVSVAKSRVAAYVKAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPNIVRSLVNQV 247
           EIS I  V K  +    + +  ++    K   ++ T D+V++F   L +   VR    ++
Sbjct: 174 EISDIARVEKKEIGRSYRFIARNLNLTPKKLFVKPT-DYVNKFADELGLSEKVRRRAIEI 232

Query: 248 ARAAAEKDGIHGRTLVSIAAGAIYFVLLLWRETCPQ-SIPATLRVSDEALVNRIAEV 303
              A  +    G++   + A A+Y   LL  E   Q  +    RV++  + NR  E+
Sbjct: 233 LEEAYRRGLTSGKSPAGLVAAALYIASLLEGEKRTQREVAEVARVTEVTVRNRYKEL 289

emb|CAB49598.1| TATA box binding protein TFIIB-BBRE complex, chain B [Pyrococcus abyssi GE5]
sp|Q9V0V5|TF2B_PYRAB Transcription initiation factor IIB (TFIIB)
ref|NP_126367.1| transcription initiation factor IIB [Pyrococcus abyssi GE5]
(300 aa)

Score: 101 bits (252), Expect: 2.81982e-20
Length: 297, Idn/Pos/Gap = 86/142/19 (28%/47%/6%)

Query:  13 VCGECGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSINP  72
           VC  CGST+ + D + G++VCA+CG V  E ++D+G EWR F+        +R G   + 
Sbjct:   6 VCPVCGSTEFIYDPERGEIVCARCGYVIEENIVDMGPEWRAFDASQRE-KRSRTGAPESI  64

Query:  73 LL-DSGLATSISQGPAGANALNE---RLARAQSR-NVLDANDRYVTECYNRISYLCERSG 127
           LL D GL+T I    +    + E   RL + QSR  V DA +R +    + +  +  +  
Sbjct:  65 LLHDKGLSTDIGIDRSLTGLMREKMYRLRKWQSRLRVSDAAERNLAFALSELDRITAQLK 124

Query: 128 LPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRTFN 187
           LP+ V++ A  L R          + VR +   R     S+I+A ++ ACR    PRT +
Sbjct: 125 LPKHVEEEAARLYR----------EAVR-KGLIRGRSIESVIAACVYAACRLLKVPRTLD 173

Query: 188 EISVIVSVAKSRVAAYVKAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPNIVRSLVNQV 247
           EIS I  V K  +    + +  ++    K   ++ T D+V++F   L +   VR    ++
Sbjct: 174 EISDIARVEKKEIGRSYRFIARNLNLTPKKLFVKPT-DYVNKFADELGLSEKVRRRAIEI 232

Query: 248 ARAAAEKDGIHGRTLVSIAAGAIYFVLLLWRETCPQ-SIPATLRVSDEALVNRIAEV 303
              A ++    G++   + A A+Y   LL  E   Q  +    RV++  + NR  E+
Sbjct: 233 LEEAYKRGLTSGKSPAGLVAAALYIASLLEGEKRTQREVAEVARVTEVTVRNRYKEL 289

ref|NP_111602.1| Transcription initiation factor IIB [Thermoplasma volcanium GSS1]
dbj|BAB60249.1| transcription initiation factor B [TFB] [Thermoplasma volcanium GSS1]
sp|Q979Q3|TF2B1_THEVO Transcription initiation factor IIB 1 (TFIIB 1)
(312 aa)

Score: 101 bits (251), Expect: 3.93701e-20
Length: 310, Idn/Pos/Gap = 84/140/40 (27%/45%/12%)

Query:  14 CGECGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSIN-P  72
           C ECGST+L+ D ++G+LVC +CG V  +  ID G EWR F+++ +     R G  +   
Sbjct:  16 CPECGSTNLIRDYEHGELVCGECGAVIEDSYIDQGPEWRAFDSEQNE-SRARAGSPMTFT  74

Query:  73 LLDSGLATSISQG---------PAGANALNERLARAQSR-NVLDANDRYVTECYNRISYL 122
           + D GL+T IS           P    A   RL + Q R  V +A +R +++    +  +
Sbjct:  75 IHDKGLSTDISWKNKDSYGRSIPTRNRAQLYRLRKWQKRIKVSNAAERNLSQALQELERM 134

Query: 123 CERSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGF 182
                +P  V++ A  + R       +  + +R R+         +++ AL+ ACR    
Sbjct: 135 AFNLSIPNDVRETAAVIYR-----KAVKQNMIRGRS------IEGVVAGALYAACRITNV 183

Query: 183 PRTFNEISVIVSVAKSRVAAYVKAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPNIVRS 242
           PRT  EI+ +  V K  +    + M   +      S+    +D++SRFCS L++    R+
Sbjct: 184 PRTLGEIASVTRVKKKEIGRTYRIMSRYLKLNIMPSK---AEDYISRFCSKLKLSMDTRN 240

Query: 243 LVNQVARAAAEKDGIHGRTLVSIAAGAIYFVLLLWRETCPQSIPATLRVSDEALVNRIAE 302
              ++ R A       G+    +AA AIY   L+  E   Q                +AE
Sbjct: 241 KALEILRDAENVGLTSGKGPTGVAAAAIYIASLITGERRTQ--------------RAVAE 286

Query: 303 VSGITEGVVK 312
           V+G+TE  ++
Sbjct: 287 VAGVTEVTIR 296

ref|YP_024116.1| transcription initiation factor IIB [Picrophilus torridus DSM 9790]
gb|AAT43923.1| transcription initiation factor IIB [Picrophilus torridus DSM 9790]
(310 aa)

Score: 101 bits (251), Expect: 4.4993e-20
Length: 309, Idn/Pos/Gap = 80/137/38 (25%/44%/12%)

Query:  14 CGECGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSINPL  73
           C ECGS+ LV D + G+L+C+ CG+V  +  ID G EWR F+++ +             +
Sbjct:  14 CPECGSSQLVRDYERGELICSNCGLVIDDSYIDEGPEWRAFDSEQNESRARTGSPMTYTI  73

Query:  74 LDSGLATSISQG---------PAGANALNERLARAQSR-NVLDANDRYVTECYNRISYLC 123
            D GL+T IS           P    A   RL + Q R  V +A +R +++    +  + 
Sbjct:  74 HDKGLSTDISWKNKDSYGKSIPTRNRAQLYRLRKWQKRIKVSNAAERNLSQALQELERMT 133

Query: 124 ERSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFP 183
               +P  V++ A  + R       +  + +R R+         +++ +++ ACR    P
Sbjct: 134 SNLSIPNDVRETAAVIYR-----KAVKQNMIRGRS------IEGVVAGSIYAACRITNVP 182

Query: 184 RTFNEISVIVSVAKSRVAAYVKAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPNIVRSL 243
           RT +EI+ +  V K  +    + M   +      S+    +D+V+RFCS L +    R  
Sbjct: 183 RTLDEIASVTRVKKKEIGRTYRIMARYLKLNIMPSK---PEDYVNRFCSKLRLSMEARKR 239

Query: 244 VNQVARAAAEKDGIHGRTLVSIAAGAIYFVLLLWRETCPQSIPATLRVSDEALVNRIAEV 303
             ++ + A + D   G+    +AA AIY   L+  E   Q                IAEV
Sbjct: 240 AEEILKMAVDNDLTSGKGPTGVAAAAIYIASLITGERRTQ--------------RAIAEV 285

Query: 304 SGITEGVVK 312
           +G+TE  ++
Sbjct: 286 AGVTEVTIR 294

ref|XP_475838.1| putative transcription initiation factor IIB (TFIIB) [Oryza sativa (japonica cultivar-group)]
gb|AAT39241.1| putative transcription initiation factor IIB (TFIIB) [Oryza sativa (japonica cultivar-group)]
gb|AAW56898.1| putative transcription initiation factor TFIIB [Oryza sativa (japonica cultivar-group)]
(316 aa)

Score: 98 bits (244), Expect: 2.63851e-19
Length: 312, Idn/Pos/Gap = 88/140/38 (28%/44%/12%)

Query:  14 CGECG-STDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSA--YDPNRVGGSI  70
           C +C  +T +V D   GD +C +C +V     ID   EWRTF ND ++   DPNRVG   
Sbjct:  12 CPDCRRATAVVLDHTTGDTICTECALVLDARYIDETSEWRTFANDGASDDRDPNRVGDRA  71

Query:  71 NPLLDS---GLATSISQGPAGANALNERLARAQSRNVLDANDRYVTECYNRISYLCERSG 127
           +P L     G   + S  P  +      L R +   V  + +  +   +  I+ + +R G
Sbjct:  72 DPFLPDHVGGTTIAYSSAPPKSADAAPLLTRRRVDVVGPSPENALVAAFRGIADMADRLG 131

Query: 128 LPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRTFN 187
           L   ++DRA E+ +   +  T G      R R R+    ++ +A LFIACRNEG PRT+ 
Sbjct: 132 LVATIRDRAKEVFKKLGEAPTKGL----PRGRNRD----AVYAACLFIACRNEGMPRTYK 183

Query: 188 EISVIV---SVAKSRVAAYVKAMEMSIGE-----AAKISRIRTTDDFVSRFCSYLEIPNI 239
           E++ +    + AK  +      ++  +G+     A  I  +R+T D++ RFCS L + + 
Sbjct: 184 ELASVTAEGAAAKKEIGRLTTLIKKHLGDQGEGRAMDIGVVRST-DYLRRFCSRLGLGHQ 242

Query: 240 VRSLVNQVARAAAEKDGIHGRTLVSIAAGAIYFVLLLWRETCPQSIPATLRVSDEALVNR 299
                    R   E+  +  R   SIAA  IY V+               R      V  
Sbjct: 243 DVRAAGDAVRRLEERLDVR-RNPESIAAAIIYMVV--------------QRAGGSKSVRD 287

Query: 300 IAEVSGITEGVV 311
           ++  +G+ EG +
Sbjct: 288 VSTATGVAEGTI 299

ref|NP_070128.1| transcription initiation factor IIB [Archaeoglobus fulgidus DSM 4304]
gb|AAB89947.1| transcription initiation factor IIB [Archaeoglobus fulgidus DSM 4304]
pir||B69412 transcription initiation factor IIB homolog - Archaeoglobus fulgidus
sp|O28970|TF2B_ARCFU Transcription initiation factor IIB (TFIIB)
(326 aa)

Score: 98 bits (244), Expect: 2.7972e-19
Length: 317, Idn/Pos/Gap = 84/147/41 (26%/46%/12%)

Query:   7 ERDVPDVCGECGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRV  66
           E DV +VC ECGS  L+ D + G+ +C  CG+V  +  ID G EWR F+++      +RV
Sbjct:  24 EEDV-EVCPECGSPRLIRDYRRGEFICQDCGLVIEDTYIDAGPEWRAFDSEQRD-KRSRV  81

Query:  67 GGSIN-PLLDSGLATSI--SQGPAGANALNE-------RLARAQSR-NVLDANDRYVTEC 115
           G  +   + D GL+T I  S       A++        RL + Q R  + +A +R +   
Sbjct:  82 GAPVTYTIHDKGLSTIIDWSNKDYYGKAISVRNRAQLFRLRKWQRRIRISNATERNLAFA 141

Query: 116 YNRISYLCERSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFI 175
            + +  +    GLP+ V++ A  + R       +  + +R R+         +++AAL+ 
Sbjct: 142 LSELDRMASALGLPKSVRETAAVIYR-----KAVEKNLIRGRS------IEGVVAAALYA 190

Query: 176 ACRNEGFPRTFNEISVIVSVAKSRVAAYVKAMEMSIGEAAKISRIRTTDDFVSRFCSYLE 235
           ACR  G PRT +EI+    V +  +    + +   +G     +   +  D++ RFC+ L 
Sbjct: 191 ACRQAGVPRTLDEIATYSRVDRKEIGRTYRFITRELGLKLMPT---SPADYIPRFCAALG 247

Query: 236 IPNIVRSLVNQVARAAAEKDGIHGRTLVSIAAGAIYFVLLLWRETCPQSIPATLRVSDEA 295
           +   V+    ++ + A E++   GR    +AA A+Y   +L  E   Q            
Sbjct: 248 LSGEVQKKAIEIIKKAEERELTSGRGPTGVAAAALYVASILLGERRTQ------------ 295

Query: 296 LVNRIAEVSGITEGVVK 312
               +AEV+G+TE  ++
Sbjct: 296 --REVAEVAGVTEVTIR 310

ref|YP_142604.1| putative transcription initiation factor IIB [Acanthamoeba polyphaga mimivirus]
gb|AAV50522.1| putative transcription initiation factor IIB [Acanthamoeba polyphaga mimivirus]
(461 aa)

Score: 96 bits (239), Expect: 1.03666e-18
Length: 326, Idn/Pos/Gap = 89/144/38 (27%/44%/11%)

Query:   3 APTMERDVPDVCGECGST-DLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAY  61
           +PT  R    +C  CGS   L+ED  +  LVC++CG++  +LL D G EWR + NDD   
Sbjct: 138 SPTKSR----ICSGCGSKGTLLEDQSSSVLVCSECGMINDDLL-DHGPEWRQYYNDDGRG 192

Query:  62 DP-NRVGGSINPLLDSGLATSISQGPAGANALNERLARAQSRNVLDANDRYVTECYNRIS 120
           +  NR G   N           SQG   A   + RL R Q  N     +R + + + +IS
Sbjct: 193 EGVNRCGCPSNFFFPKS-----SQGTILAGTGSGRLKRKQKWNSTVYKERSLNDVFEKIS 247

Query: 121 YLCERSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNE 180
            +C +S +P+++ D A  L +   D      + V  +   R     SII+A ++ AC   
Sbjct: 248 TICSKSNIPRIIADTAKILYKKLSDCKHKSGNNVGKQIIIRGHNRISIIAACIYKACEMN 307

Query: 181 GFPRTFNEISVIVSVAKSRVAAYVKAMEMSIGEAAKISRI------RTTDDFVSRFCSYL 234
             PRT  EI+    + + +V    K  E  +        I       +T+D++ R C  L
Sbjct: 308 KNPRTVKEIARFFGIDEKKVTKGNKQFEKIMKNTDDNMIILDPVNSNSTEDYIRRHCPRL 367

Query: 235 EI----PNIVRSLVNQVARAAAEKDGIHGRTLVSIAAGAIYFVLLLWRETCPQSIPATLR 290
           ++     +I   + N   R     D        SIAAGAI  +++     C  +I     
Sbjct: 368 KVNKDHTDIAVKISNNCCRMKLASD----HNPQSIAAGAILVMVVF----CELNI----- 414

Query: 291 VSDEALVNRIAEVSGIT-EGVVKTVA 315
             D+  ++R+  +S +T + + K +A
Sbjct: 415 --DKRKISRLFGISDVTIDKIYKKIA 438

pir||S34116 transcription factor IIB - Pyrococcus woesei
(300 aa)

Score: 96 bits (238), Expect: 1.38824e-18
Length: 297, Idn/Pos/Gap = 84/142/19 (28%/47%/6%)

Query:  13 VCGECGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSINP  72
           VC  C S +L+ D + G++VCA+CG V  E +ID+G EWR F+        +R G   + 
Sbjct:   6 VCPACESAELIYDPERGEIVCAKCGYVIEENIIDMGPEWRAFDASQRERR-SRTGAPESI  64

Query:  73 LL-DSGLATSISQGPAGANALNE---RLARAQSR-NVLDANDRYVTECYNRISYLCERSG 127
           LL D GL+T I    + +  + E   RL + QSR  V DA +R +    + +  +  +  
Sbjct:  65 LLHDKGLSTEIGIDRSLSGLMREKMYRLRKWQSRLRVSDAAERNLAFALSELDRITAQLK 124

Query: 128 LPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRTFN 187
           LP+ V++ A  L R          + VR +   R     S+++A ++ ACR    PRT +
Sbjct: 125 LPRHVEEEAARLYR----------EAVR-KGLIRGRSIESVMAACVYAACRLLKVPRTLD 173

Query: 188 EISVIVSVAKSRVAAYVKAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPNIVRSLVNQV 247
           EI+ I  V K  +    + +  ++    K   ++ T D+V++F   L +   VR    ++
Sbjct: 174 EIADIARVDKKEIGRSYRFIARNLNLTPKKLFVKPT-DYVNKFADELGLSEKVRRRAIEI 232

Query: 248 ARAAAEKDGIHGRTLVSIAAGAIYFVLLLWRETCPQ-SIPATLRVSDEALVNRIAEV 303
              A ++    G++   + A A+Y   LL  E   Q  +    RV++  + NR  E+
Sbjct: 233 LDEAYKRGLTSGKSPAGLVAAALYIASLLEGEKRTQREVAEVARVTEVTVRNRYKEL 289

ref|NP_579106.1| transcription initiation factor IIB chain b [Pyrococcus furiosus DSM 3638]
gb|AAL81501.1| transcription initiation factor IIB chain b; (TFIIB) [Pyrococcus furiosus DSM 3638]
sp|P61999|TF2B_PYRWO Transcription initiation factor IIB (TFIIB)
sp|P61998|TF2B_PYRFU Transcription initiation factor IIB (TFIIB)
gb|AAC43724.1| TFIIB
(300 aa)

Score: 96 bits (238), Expect: 1.44738e-18
Length: 297, Idn/Pos/Gap = 84/142/19 (28%/47%/6%)

Query:  13 VCGECGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSINP  72
           VC  C S +L+ D + G++VCA+CG V  E +ID+G EWR F+        +R G   + 
Sbjct:   6 VCPACESAELIYDPERGEIVCAKCGYVIEENIIDMGPEWRAFDASQRERR-SRTGAPESI  64

Query:  73 LL-DSGLATSISQGPAGANALNE---RLARAQSR-NVLDANDRYVTECYNRISYLCERSG 127
           LL D GL+T I    + +  + E   RL + QSR  V DA +R +    + +  +  +  
Sbjct:  65 LLHDKGLSTEIGIDRSLSGLMREKMYRLRKWQSRLRVSDAAERNLAFALSELDRITAQLK 124

Query: 128 LPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRTFN 187
           LP+ V++ A  L R          + VR +   R     S+++A ++ ACR    PRT +
Sbjct: 125 LPRHVEEEAARLYR----------EAVR-KGLIRGRSIESVMAACVYAACRLLKVPRTLD 173

Query: 188 EISVIVSVAKSRVAAYVKAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPNIVRSLVNQV 247
           EI+ I  V K  +    + +  ++    K   ++ T D+V++F   L +   VR    ++
Sbjct: 174 EIADIARVDKKEIGRSYRFIARNLNLTPKKLFVKPT-DYVNKFADELGLSEKVRRRAIEI 232

Query: 248 ARAAAEKDGIHGRTLVSIAAGAIYFVLLLWRETCPQ-SIPATLRVSDEALVNRIAEV 303
              A ++    G++   + A A+Y   LL  E   Q  +    RV++  + NR  E+
Sbjct: 233 LDEAYKRGLTSGKSPAGLVAAALYIASLLEGEKRTQREVAEVARVTEVTVRNRYKEL 289

ref|NP_279370.1| TfbG [Halobacterium sp. NRC-1]
gb|AAG18850.1| transcription initiation factor IIB; TfbG [Halobacterium sp. NRC-1]
pir||F84185 transcription initiation factor IIB [imported] - Halobacterium sp. NRC-1
sp|Q9HSF7|TF2B7_HALN1 Transcription initiation factor IIB 7 (TFIIB 7)
(323 aa)

Score: 95 bits (237), Expect: 1.85905e-18
Length: 301, Idn/Pos/Gap = 89/138/27 (29%/45%/8%)

Query:  14 CGECGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGG-SINP  72
           C ECGS +LV+ +   +LVC  CG+V  E  ID G EWR F N     + +RVG  +   
Sbjct:  29 CPECGSDNLVKSSDRAELVCNDCGLVVEEEQIDPGPEWRAF-NHQERQEKSRVGAPTTQT  87

Query:  73 LLDSGLATSISQGPAGANALN---------ERLARAQSR-NVLDANDRYVTECYNRISYL 122
           + D GL T+I      A   +          RL + Q R    DA +R +    + I  +
Sbjct:  88 MHDKGLTTTIDWKDKDAYGRSISSKKRSQMHRLRKWQERIRTKDAGERNLQFALSEIDRM 147

Query: 123 CERSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGF 182
               G+P+ V++ A  + R       L  D +R R+         + ++AL+ ACR EG 
Sbjct: 148 ASALGVPRSVREVASVIYR-----RALKEDLIRGRS------IEGVATSALYAACRKEGI 196

Query: 183 PRTFNEISVIVSVAKSRVAAYVKAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPNIVRS 242
           PR+  EIS +  V +  +    + +   +G   K    +    +V RFCS LE+   V+S
Sbjct: 197 PRSLEEISEVSRVERKEIGRTYRYISQELGLEMKPVDPKK---YVPRFCSELELTEEVQS 253

Query: 243 LVNQVARAAAEKDGIHGRTLVSIAAGAIYFVLLLWRETCPQ-SIPATLRVSDEALVNRIA 301
             N++    AE+  + G++    AA AIY   LL  E   Q  +    +V++  + NR  
Sbjct: 254 KANEIIETTAEEGLLSGKSPTGYAAAAIYAASLLCNEKKTQREVADVAQVTEVTIRNRYQ 313

Query: 302 E 302
           E
Sbjct: 314 E 314

pdb|1C9B|Q Chain Q, Crystal Structure Of A Human Tbp Core Domain-Human Tfiib Core Domain Complex Bound To An Extended, Modified Adenoviral Major Late Promoter (Admlp)
pdb|1C9B|M Chain M, Crystal Structure Of A Human Tbp Core Domain-Human Tfiib Core Domain Complex Bound To An Extended, Modified Adenoviral Major Late Promoter (Admlp)
pdb|1C9B|I Chain I, Crystal Structure Of A Human Tbp Core Domain-Human Tfiib Core Domain Complex Bound To An Extended, Modified Adenoviral Major Late Promoter (Admlp)
pdb|1C9B|E Chain E, Crystal Structure Of A Human Tbp Core Domain-Human Tfiib Core Domain Complex Bound To An Extended, Modified Adenoviral Major Late Promoter (Admlp)
pdb|1C9B|A Chain A, Crystal Structure Of A Human Tbp Core Domain-Human Tfiib Core Domain Complex Bound To An Extended, Modified Adenoviral Major Late Promoter (Admlp)
(207 aa)

Score: 93 bits (232), Expect: 6.71942e-18
Length: 240, Idn/Pos/Gap = 70/115/37 (29%/47%/15%)

Query: 108 NDRYVTECYNRISYLCERSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETAS 167
           +DR +   +  I+ + +R  LP+ + DR   L +  Y+  +L     + RA        +
Sbjct:   1 SDRAMMNAFKEITTMADRINLPRNIVDRTNNLFKQVYEQKSL-----KGRA------NDA  49

Query: 168 IISAALFIACRNEGFPRTFNEISVIVSVAKSRVAA----YVKAMEMSIGEAAKISRIRTT 223
           I SA L+IACR EG PRTF EI  +  ++K  +       +KA+E S+        + TT
Sbjct:  50 IASACLYIACRQEGVPRTFKEICAVSRISKKEIGRCFKLILKALETSVD-------LITT 102

Query: 224 DDFVSRFCSYLEIPNIVRSLVNQVARAAAEKDGIHGRTLVSIAAGAIYFVLLLWRETCPQ 283
            DF+SRFCS L +P  V+     +AR A E D + GR+ +S+AA AIY            
Sbjct: 103 GDFMSRFCSNLCLPKQVQMAATHIARKAVELDLVPGRSPISVAAAAIYM----------- 151

Query: 284 SIPATLRVSDEALVNRIAEVSGITEGVVKTVASRIRQYRDRGLLPPDWVRRFPSRLEPEL 343
              A+   +++     I +++G+ +  ++  + R+   R   L P D+    P    P+L
Sbjct: 152 ---ASQASAEKRTQKEIGDIAGVADVTIRQ-SYRLIYPRAPDLFPTDFKFDTPVDKLPQL 207

dbj|BAD85469.1| transcription initiation factor IIB [Thermococcus kodakaraensis KOD1]
ref|YP_183693.1| transcription initiation factor IIB [Thermococcus kodakaraensis KOD1]
(300 aa)

Score: 93 bits (231), Expect: 8.70292e-18
Length: 297, Idn/Pos/Gap = 83/136/19 (27%/45%/6%)

Query:  13 VCGECGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSINP  72
           VC  CGST+ + D   G++VC  CG V  E ++D G EWR F+         RVG   + 
Sbjct:   6 VCPVCGSTEFIYDPSRGEIVCKVCGYVIEENVVDEGPEWRAFDPGQREKRA-RVGAPESI  64

Query:  73 LL-DSGLATSISQGPAGANALNE---RLARAQSR-NVLDANDRYVTECYNRISYLCERSG 127
           LL D GL+T I    +    + E   RL + QSR  V DA +R +    + +  L     
Sbjct:  65 LLHDKGLSTDIGIDRSLTGLMREKMYRLRKWQSRLRVSDAAERNLAFALSELDRLASNLS 124

Query: 128 LPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRTFN 187
           LP+ V++ A  L R          + VR +   R     ++I+A ++ ACR    PRT +
Sbjct: 125 LPKHVEEEAARLYR----------EAVR-KGLIRGRSIEAVIAACVYAACRLLKVPRTLD 173

Query: 188 EISVIVSVAKSRVAAYVKAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPNIVRSLVNQV 247
           EI+ +  V K  +    + +   +    K   ++ T D+V++F   L +   VR    ++
Sbjct: 174 EIADVSRVDKKEIGRSFRFIARHLNLTPKKLFVKPT-DYVNKFADELGLSEKVRRRAIEI 232

Query: 248 ARAAAEKDGIHGRTLVSIAAGAIYFVLLLWRETCPQ-SIPATLRVSDEALVNRIAEV 303
              A ++    G++   + A A+Y   L+  E   Q  +    RV++  + NR  E+
Sbjct: 233 LEEAYQRGLTSGKSPAGLVAAALYIASLMEGEKRTQREVAEVARVTEVTVRNRYKEL 289

gb|AAB85383.1| transcription initiation factor TFIIB [Methanothermobacter thermautotrophicus str. Delta H]
ref|NP_276022.1| transcription initiation factor TFIIB [Methanothermobacter thermautotrophicus str. Delta H]
pir||C69218 transcription initiation factor TFIIB - Methanobacterium thermoautotrophicum (strain Delta H)
sp|O26971|TF2B_METTH Transcription initiation factor IIB (TFIIB)
(310 aa)

Score: 93 bits (230), Expect: 1.05441e-17
Length: 337, Idn/Pos/Gap = 89/149/45 (26%/44%/13%)

Query:   6 MERDVPDV-----CGECGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSA  60
           M  DV ++     C ECGS DL  D +  ++VC +CG+V  + L+D+G EWR F+++   
Sbjct:   1 MRSDVSEIEKETKCPECGSDDLRGDYERAEIVCGKCGLVIDDNLVDMGPEWRAFDHEQRD  60

Query:  61 YDPNRVGGSIN-PLLDSGLATSIS---------QGPAGANALNERLARAQSR-NVLDAND 109
               RVG  I   + D GL+T I            PA   A   RL + Q +  +  A +
Sbjct:  61 -KRTRVGAPITYTIHDKGLSTMIDWRNKDIYGRDIPARNRAQWYRLRKWQRKIRISGATE 119

Query: 110 RYVTECYNRISYLCERSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASII 169
           R +    + +     R GLP+ V++ A  + R   ++       +R R+         ++
Sbjct: 120 RNLAFALSELDRDSSRLGLPRSVREAASMVYRRAVENKL-----IRGRS------IEGVV 168

Query: 170 SAALFIACRNEGFPRTFNEISVIVSVAKSRVAAYVKAMEMSIGEAAKISRIRTTDDFVSR 229
           +A+L+ ACR    PRT +EI+ +  V+K  V    + +   +      +   +  D+V R
Sbjct: 169 AASLYAACRKCNVPRTLDEIAEVSRVSKKEVGRTYRFLTRELNIKLPPT---SPVDYVPR 225

Query: 230 FCSYLEIPNIVRSLVNQVARAAAEKDGIHGRTLVSIAAGAIYFVLLLWRETCPQSIPATL 289
           F S L +   V+S   ++   A E     GR    +AA A+Y   +L  E   Q      
Sbjct: 226 FASELGLSGEVQSKAIEIIEMAMENGLTSGRGPTGVAAAALYIASVLLGEHKTQ------ 279

Query: 290 RVSDEALVNRIAEVSGITEGVVKTVASRIRQYRDRGL 326
                     +AEV+G+TE  ++     + +  D G+
Sbjct: 280 --------RDVAEVAGVTEVTIRNRYKELTEQLDLGV 308

pdb|1TFB| Nmr Studies Of Human General Transcription Factor Tfiib: Dynamics And Interaction With Vp16 Activation Domain, 20 Structures
(208 aa)

Score: 91 bits (226), Expect: 3.44799e-17
Length: 238, Idn/Pos/Gap = 69/113/37 (28%/47%/15%)

Query: 110 RYVTECYNRISYLCERSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASII 169
           R +   +  I+ + +R  LP+ + DR   L +  Y+  +L     + RA        +I 
Sbjct:   4 RAMMNAFKEITTMADRINLPRNIVDRTNNLFKQVYEQKSL-----KGRA------NDAIA  52

Query: 170 SAALFIACRNEGFPRTFNEISVIVSVAKSRVAA----YVKAMEMSIGEAAKISRIRTTDD 225
           SA L+IACR EG PRTF EI  +  ++K  +       +KA+E S+        + TT D
Sbjct:  53 SACLYIACRQEGVPRTFKEICAVSRISKKEIGRCFKLILKALETSVD-------LITTGD 105

Query: 226 FVSRFCSYLEIPNIVRSLVNQVARAAAEKDGIHGRTLVSIAAGAIYFVLLLWRETCPQSI 285
           F+SRFCS L +P  V+     +AR A E D + GR+ +S+AA AIY              
Sbjct: 106 FMSRFCSNLCLPKQVQMAATHIARKAVELDLVPGRSPISVAAAAIYM------------- 152

Query: 286 PATLRVSDEALVNRIAEVSGITEGVVKTVASRIRQYRDRGLLPPDWVRRFPSRLEPEL 343
            A+   +++     I +++G+ +  ++  + R+   R   L P D+    P    P+L
Sbjct: 153 -ASQASAEKRTQKEIGDIAGVADVTIRQ-SYRLIYPRAPDLFPTDFKFDTPVDKLPQL 208

pir||C88922 protein W03F9.5 [imported] - Caenorhabditis elegans
(148 aa)

Score: 90 bits (224), Expect: 5.45591e-17
Length: 134, Idn/Pos/Gap = 56/79/10 (41%/58%/7%)

Query:   1 MSAPTMERDVPDVCGECGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSA  60
           MSAP      PDV        L+ED + GDLVC  CG+V  + L+D+G EWR+F N+ S 
Sbjct:   1 MSAPVQCPIHPDV-------HLIEDHRAGDLVCPACGLVVGDRLVDVGTEWRSFSNERSG  53

Query:  61 YDPNRVGGSINPLLDSG-LATSISQGPAGANALNERLARAQSRNVLDANDRYVTECYNRI 119
            DP+RVG   NPLL  G L+T+I+ G  G+++ N  LA AQ R  ++  DR +T   + I
Sbjct:  54 NDPSRVGAPENPLLSGGDLSTTIAVGFGGSDSDNS-LANAQ-RKSMNNTDRQMTAAMSLI 111

Query: 120 SYLCERSGLPQLVK 133
             + ER  LP+ ++
Sbjct: 112 REMSERIHLPRNIQ 125

emb|CAF29597.1| transcription initiation factor B [Methanococcus maripaludis S2]
ref|NP_987161.1| transcription initiation factor B [Methanococcus maripaludis S2]
(339 aa)

Score: 90 bits (222), Expect: 1.07246e-16
Length: 333, Idn/Pos/Gap = 91/153/48 (27%/45%/14%)

Query:   6 MERDVPDVCGECGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNR  65
           +E++   +C  CGS  +++D +  ++VC  CG V  + L D+G EWR F+++      +R
Sbjct:  35 LEKEEELICPVCGSKSIIKDYERAEIVCEMCGCVLQQNLFDVGPEWRAFDHEQRV-KRSR  93

Query:  66 VGGSIN-PLLDSGLATSI------SQG---PAGANALNERLARAQSR-NVLDANDRYVTE 114
           VG  +   + D GL+T I      S G    A   A   RL + Q R  V DA++R +  
Sbjct:  94 VGAPMTYTIHDKGLSTVIDWRNKDSYGKDISADKRAQLYRLRKWQRRIRVSDASERNLAF 153

Query: 115 CYNRISYLCERSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALF 174
             + +  +  + GLP+ V++ A  L R           G   +   R      + +AAL+
Sbjct: 154 ALSELDRIASKLGLPRNVRENAAVLYR-----------GAVEKGLIRGRSIEGVAAAALY 202

Query: 175 IACRNEGFPRTFNEISVIVSVAKSRVAAYVK--AMEMSIGEAAKISRIRTTD--DFVSRF 230
            ACR    PRT +EI+ +  V +  +    +  + E++I       R+  T+  D+V RF
Sbjct: 203 AACRRCKVPRTLDEIAEVSRVDRKEIGRTYRFISRELNI-------RLAPTNPVDYVPRF 255

Query: 231 CSYLEIPNIVRSLVNQVARAAAEKDGIHGRTLVSIAAGAIYFVLLLWRETCPQSIPATLR 290
            S L++P  V S    + + A E+    GR    +AA AIY   +L           T R
Sbjct: 256 ASELKLPGEVESKAISILQKAGERGLTSGRGPTGVAAAAIYIASVL---------QGTRR 306

Query: 291 VSDEALVNRIAEVSGITEGVVKTVASRIRQYRD 323
              E     +A+V+G+TE  ++     + ++ D
Sbjct: 307 TQRE-----VADVAGVTEVTIRNRYKELTEHLD 334

pdb|1VOL|A Chain A, Tfiib (Human Core Domain)TBP (A.THALIANA)TATA ELEMENT Ternary Complex
(204 aa)

Score: 89 bits (220), Expect: 1.697e-16
Length: 232, Idn/Pos/Gap = 69/110/37 (29%/47%/15%)

Query: 116 YNRISYLCERSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFI 175
           +  I+ + +R  LP+   DR   L R  Y+  +L     + RA        +I SA L+I
Sbjct:   6 FKEITTMADRINLPRNKVDRTNNLFRQAYEQKSL-----KGRA------NDAIASACLYI  54

Query: 176 ACRNEGFPRTFNEISVIVSVAKSRVAA----YVKAMEMSIGEAAKISRIRTTDDFVSRFC 231
           ACR EG PRTF EI  +  ++K  +       +KA+E S+        + TT DF+SRFC
Sbjct:  55 ACRQEGVPRTFKEICAVSRISKKEIGRCFKLILKALETSVD-------LITTGDFMSRFC 107

Query: 232 SYLEIPNIVRSLVNQVARAAAEKDGIHGRTLVSIAAGAIYFVLLLWRETCPQSIPATLRV 291
           S L +P  V+     +AR A E D + GR+ +S+AA AIY               A+   
Sbjct: 108 SNLCLPKQVQMAATHIARKAVELDLVPGRSPISVAAAAIYM--------------ASQAS 153

Query: 292 SDEALVNRIAEVSGITEGVVKTVASRIRQYRDRGLLPPDWVRRFPSRLEPEL 343
           +++     I +++G+ +  ++  + R+   R   L P D+    P    P+L
Sbjct: 154 AEKRTQKEIGDIAGVADVTIRQ-SYRLIYPRAPDLFPTDFKFDTPVDKLPQL 204

gb|AAR28031.1| mutant TFIIB3 [Arabidopsis thaliana]
(336 aa)

Score: 88 bits (219), Expect: 2.27253e-16
Length: 240, Idn/Pos/Gap = 72/114/25 (30%/47%/10%)

Query:  12 DVCGECGS-TDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDD--SAYDPNRVGG  68
           + C +C   T +V D  +GD +C++CG+V    +I+   EWRTF +DD  S  DPNRVG 
Sbjct:   4 ETCLDCKRPTIMVVDHSSGDTICSECGLVLEAHIIEYSQEWRTFASDDNHSDRDPNRVGA  63

Query:  69 SINPLLDSGLATSISQGP--AGANALNE----RLARAQSRNVLDANDRYVTECYNRISYL 122
           + NP L SG   +I + P    ++ L++     L RA ++ V +  +  + + +  I  +
Sbjct:  64 ATNPFLKSGDLVTIIEKPKETASSVLSKDDISTLFRAHNQ-VKNHEEDLIKQAFEEIQRM 122

Query: 123 CERSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAA-LFIACRNEG 181
            +   L  ++  RACE++  Y  H         A  + R  +  + I AA +  ACR   
Sbjct: 123 TDALDLDIVINSRACEIVSKYDGH---------ANTKLRRGKKLNAICAASVSTACRELQ 173

Query: 182 FPRTFNEISVI---VSVAKSRVAAYV--KAMEMSIGEAAKISRIRTTDDFVSRFCSYLEI 236
             RT  EI+ +   V     R  + V  + +E      +    I  T D V RFCS L+I
Sbjct: 174 LSRTLKEIAEVANGVDKKDIRKESLVIKRVLESHQTSVSASQAIINTGDLVRRFCSKLDI 233

emb|CAB69073.1| archaeal transcription factor B [Methanothermococcus thermolithotrophicus]
sp|Q9P9I7|TF2B_METTL Transcription initiation factor IIB (TFIIB)
(339 aa)

Score: 88 bits (218), Expect: 3.12039e-16
Length: 333, Idn/Pos/Gap = 92/153/48 (27%/45%/14%)

Query:   6 MERDVPDVCGECGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNR  65
           +E++   +C  CGS ++++D +  ++VC  CG V  + L D+G EWR F+++      +R
Sbjct:  35 LEKEEELICPMCGSKNIIKDYERAEIVCETCGCVLQQNLFDVGPEWRAFDHEQRV-KRSR  93

Query:  66 VGGSIN-PLLDSGLATSI------SQG---PAGANALNERLARAQSR-NVLDANDRYVTE 114
           VG  +   + D GL+T I      S G    A   A   RL + Q R  V DA++R +  
Sbjct:  94 VGPPMTYTIHDKGLSTVIDWRNKDSYGKDISADKRAQLYRLRKWQRRIRVSDASERNLAF 153

Query: 115 CYNRISYLCERSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALF 174
             + +  +  + GLP+ V++ A  L R           G   +   R      + +AAL+
Sbjct: 154 ALSELDRIASKLGLPRNVRENAAVLYR-----------GAVEKGLIRGRSIEGVAAAALY 202

Query: 175 IACRNEGFPRTFNEISVIVSVAKSRVAAYVK--AMEMSIGEAAKISRIRTTD--DFVSRF 230
            ACR    PRT +EI+    V +  +    +  + E++I       R+  T+  D+V RF
Sbjct: 203 AACRRCKVPRTLDEIAEGSRVDRKEIGRTYRFISRELNI-------RLTPTNPIDYVPRF 255

Query: 231 CSYLEIPNIVRSLVNQVARAAAEKDGIHGRTLVSIAAGAIYFVLLLWRETCPQSIPATLR 290
            S L++P  V S    + + A EK    GR    +AA AIY   +L           T R
Sbjct: 256 ASELKLPGEVESKAISILQKANEKGLTSGRGPTGVAAAAIYIASVL---------HGTRR 306

Query: 291 VSDEALVNRIAEVSGITEGVVKTVASRIRQYRD 323
              E     +A+V+G+TE  ++     + ++ D
Sbjct: 307 TQRE-----VADVAGVTEVTIRNRYKELTEHLD 334

dbj|BAB02583.1| transcription initiation factor IIB (TFIIB)-like protein [Arabidopsis thaliana]
ref|NP_189584.1| transcription factor IIB (TFIIB) family protein [Arabidopsis thaliana]
(336 aa)

Score: 87 bits (214), Expect: 7.68356e-16
Length: 240, Idn/Pos/Gap = 71/114/25 (29%/47%/10%)

Query:  12 DVCGECGS-TDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDD--SAYDPNRVGG  68
           + C +C   T +V D  +GD +C++CG+V    +I+   EWRTF +DD  S  DPNRVG 
Sbjct:   4 ETCLDCKRPTIMVVDHSSGDTICSECGLVLEAHIIEYSQEWRTFASDDNHSDRDPNRVGA  63

Query:  69 SINPLLDSGLATSISQGP--AGANALNE----RLARAQSRNVLDANDRYVTECYNRISYL 122
           + NP L SG   +I + P    ++ L++     L RA ++ V +  +  + + +  I  +
Sbjct:  64 ATNPFLKSGDLVTIIEKPKETASSVLSKDDISTLFRAHNQ-VKNHEEDLIKQAFEEIQRM 122

Query: 123 CERSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAA-LFIACRNEG 181
            +   L  ++  RACE++  Y  H         A  + R  +  + I AA +  ACR   
Sbjct: 123 TDALDLDIVINSRACEIVSKYDGH---------ANTKLRRGKKLNAICAASVSTACRELQ 173

Query: 182 FPRTFNEISVI---VSVAKSRVAAYV--KAMEMSIGEAAKISRIRTTDDFVSRFCSYLEI 236
             RT  EI+ +   V     R  + V  + +E      +    I  T + V RFCS L+I
Sbjct: 174 LSRTLKEIAEVANGVDKKDIRKESLVIKRVLESHQTSVSASQAIINTGELVRRFCSKLDI 233

ref|NP_394404.1| transcription initiation factor IIB related protein [Thermoplasma acidophilum DSM 1728]
emb|CAC12074.1| transcription initiation factor IIB related protein [Thermoplasma acidophilum]
sp|Q9HJM2|TF2B2_THEAC Transcription initiation factor IIB 2 (TFIIB 2)
(307 aa)

Score: 86 bits (213), Expect: 9.70564e-16
Length: 258, Idn/Pos/Gap = 70/119/26 (27%/46%/10%)

Query:   5 TMERDVPDVCGECGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPN  64
           T+E + P  C EC S  L+ D ++G+L+CA CG V  +  ID G EWR F++D       
Sbjct:   2 TVEGETPKRCPECNSEHLIRDYEHGELICADCGAVIEDAYIDQGPEWRAFDSDQDERRA-  60

Query:  65 RVGGSINPLL-DSGLATSISQG---------PAGANALNERLARAQSR-NVLDANDRYVT 113
           R G  +  L  D GLAT IS           P    A   R+ +   R  V +A +R ++
Sbjct:  61 RTGSPMTYLSHDKGLATEISWSNKDYYGKRIPHKNRAQIYRVRKWHQRIRVSNAAERNLS 120

Query: 114 ECYNRISYLCERSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAAL 173
                ++ +  + G+P+ +K+ A  + R       +  + +R R+        SI+ A++
Sbjct: 121 LALQLLNDIGAKLGIPKDIKETAALIYR-----KAVEKNLIRGRS------IESIVCASI 169

Query: 174 FIACRNEGFPRTFNEISVIVSVAKSRVAAYVKAMEMSIGEAAKISRIRTTDDFVSRFCSY 233
           + ACR    PRT +EIS    V K ++    + +   +    K +   T   ++S+FC+ 
Sbjct: 170 YAACRKVNIPRTLDEISKASEVNKKKIGKAYRHLAKELDLNLKPT---TPFSYISQFCNK 226

Query: 234 LEIPNIVRSLVNQVARAA 251
           L++      +   + R A
Sbjct: 227 LDLDKQAIVISEDIVRQA 244

ref|XP_470574.1| Putative transcription initiation factor IIB [Oryza sativa (japonica cultivar-group)]
gb|AAN59779.1| Putative transcription initiation factor IIB [Oryza sativa (japonica cultivar-group)]
(308 aa)

Score: 86 bits (213), Expect: 9.95165e-16
Length: 319, Idn/Pos/Gap = 87/136/36 (27%/42%/11%)

Query:  14 CGECG-STDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSA--YDPNRVGGSI  70
           C EC  +T +V D   GD +C +C +V  E  ID   EWRTF +  S    DPNRVGG  
Sbjct:  12 CPECHRTTVVVVDHATGDTICTECALVLEERYIDETSEWRTFSDAGSGEDRDPNRVGGCS  71

Query:  71 NPLLDSG-LATSISQGPAGANALNERLARAQSRNVLDANDRYVTECYNRISYLCERSGLP 129
           +P L    L T ++  PA   A +         +     D  +   +  IS + +R  L 
Sbjct:  72 DPFLSHAELGTVVA--PAKRQAKDTASPPHVRVDSKSGQDSSLAVAFRAISDMADRLQLV 129

Query: 130 QLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRTFNEI 189
             ++DRA EL +          +  +  AR R  + A   +A L IACRNEG PRT  E+
Sbjct: 130 ATIRDRAKELFK--------KMEEAKLCARVRNRDAA--YAACLHIACRNEGNPRTLKEL 179

Query: 190 SVIVSVA--KSRVAAYVKAMEMSIGEAAKISR---IRTTDDFVSRFCSYLEIPNIVRSLV 244
           + ++     K  +    + +   +GE A  +    +    D++SRF S L +        
Sbjct: 180 ASVMRDCQDKKEIGRMERIIRRHLGEEAGTAMEMGVVRAADYMSRFGSRLGMGKPEVREA 239

Query: 245 NQVARAAAEKDGIHGRTLVSIAAGAIYFVLLLWRETCPQSIPATLRVSDEALVNRIAEVS 304
            + A+   +K  +  R   SIAA  IY V+               R   +     +++ S
Sbjct: 240 QRAAQTLEDKLDVR-RNPESIAAAIIYMVV--------------QRAGAQTSARDVSKAS 284

Query: 305 GITEGVVKTVASRIRQYRD 323
           G+ E  +K     + Q+ +
Sbjct: 285 GVAEATIKEACKELSQHEE 303

ref|YP_024118.1| transcription initiation factor IIB [Picrophilus torridus DSM 9790]
gb|AAT43925.1| transcription initiation factor IIB [Picrophilus torridus DSM 9790]
(304 aa)

Score: 86 bits (212), Expect: 1.51035e-15
Length: 242, Idn/Pos/Gap = 68/111/26 (28%/45%/10%)

Query:   6 MERDVPDVCGECGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNR  65
           ME ++   C ECGS  L+ D + G+++C  CG+V  E  ID G EWR F++D       R
Sbjct:   1 MEENIGQRCPECGSGHLIRDYERGEVLCGDCGIVIEETSIDQGPEWRAFDSDQDEKRA-R  59

Query:  66 VGGSINPLL-DSGLATSISQG---------PAGANALNERLARAQSR-NVLDANDRYVTE 114
            G  ++ L  D GLAT IS           P    A   R+ +   R  V +A++R ++ 
Sbjct:  60 TGSPMSFLSHDKGLATEISWSNRDYYGKRIPHKNRAQIYRVRKWHQRIRVSNASERNLSL 119

Query: 115 CYNRISYLCERSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALF 174
               ++    + G+P+ +K+ A  + R   +           R   R     SI+ AA++
Sbjct: 120 ALQLLNDDGSKLGIPKDIKESAALIYRKAVE-----------RNLIRGRSIESIVCAAIY 168

Query: 175 IACRNEGFPRTFNEISVIVSVAKSRVAAYVKAMEMSIGEAAKISRIRTTDDFVSRFCSYL 234
            ACR    PRT +EIS    + K ++    + +   +    K +   T   +VS+FC+ L
Sbjct: 169 AACRQVNIPRTLDEISKAADINKKKIGKAYRHLAKELKLNLKPT---TPYSYVSQFCNKL 225

Query: 235 EI 236
            +
Sbjct: 226 NL 227

ref|NP_613904.1| Transcription initiation factor IIB [Methanopyrus kandleri AV19]
gb|AAM01834.1| Transcription initiation factor IIB [Methanopyrus kandleri AV19]
(341 aa)

Score: 85 bits (209), Expect: 2.73122e-15
Length: 271, Idn/Pos/Gap = 75/119/25 (27%/43%/9%)

Query:  13 VCGECGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSINP  72
           VC +CGST+L  D K+G+LVC  CG V  + LID G EWR F  D  A    R G  I+ 
Sbjct:  10 VCPKCGSTNLERDEKHGELVCRDCGTV-VDYLIDYGPEWRAFNADQRA-QRERTGAPISE  67

Query:  73 LLDSGLATSI--SQGPAGANALNERLARAQSRNVLDAND---RYVTECYNRISYLCERSG 127
                L  +I   +   G   ++ R  R +  +   +ND   R +      I  +C ++ 
Sbjct:  68 RHPHKLGDTIIDDRDTRGRRLVDWRFRRLKRWDRWISNDPVSRNIRSAVELIERVCSQAN 127

Query: 128 LPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRTFN 187
           +P+ + D A  + R       +  D VR R+        +  +AALF+AC+    PRT  
Sbjct: 128 IPRSIVDEAIRIYR-----KAVEKDLVRGRS------IENTAAAALFMACKKRKHPRTIK 176

Query: 188 EISVIVSVAKSRVAAYVKAMEMSIGEAAKISRIRTTD--DFVSRFCSYLEIPNIVRSLVN 245
           EI+ +  +    +    + +   + E     R+   D   ++SRF + L +   V  L  
Sbjct: 177 EIAKLFGITPKDINRTHRVLLRHLNE-----RMPAPDPKQYLSRFATELGVSEDVEMLAR 231

Query: 246 QVARAAAEKDGIHGRTLVSIAAGAIYFVLLL 276
           ++   A +K     R    +A  A+Y   LL
Sbjct: 232 EILEKAEKKGLTVSRNPAGLAGAALYLAGLL 262

ref|NP_963565.1| hypothetical protein NEQ276 [Nanoarchaeum equitans Kin4-M]
gb|AAR39126.1| NEQ276 [Nanoarchaeum equitans Kin4-M]
(315 aa)

Score: 85 bits (209), Expect: 2.7541e-15
Length: 255, Idn/Pos/Gap = 68/115/24 (26%/45%/9%)

Query:  13 VCGECGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSIN-  71
           VC  CGS +++ D K G+ +C  CG V  ++  DLG EWR F  DD   D  R G  ++ 
Sbjct:  10 VCPNCGSENIIYDPKTGEYICKDCGYV-IKIEFDLGPEWRHF--DDETVDRRRGGAPLSY  66

Query:  72 PLLDSGLATSISQGPAGANALNE------RLARAQSRNVLDANDRYVTECYNRISYLCER 125
             +  GL+T I           E      R+ +  SR  L A DR +    + +  + ++
Sbjct:  67 AKVGRGLSTEIGDTSEIYKLKGELKQKFMRMRKWHSRVALSAIDRNLKIALHELKKMVDK 126

Query: 126 SGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRT 185
             +P+ V++ A    R+Y   +  G     AR R       ++++  L++  R    PRT
Sbjct: 127 LNMPKYVEEEAA---RIYQKVVEKGL----ARGR----NINTLLAGTLYLVIREYNIPRT 175

Query: 186 FNEISVIVSVAKSRVAAYVKAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPNIVRSLVN 245
             E+     ++K  +A   KA  + + E     +  +  DFV R+ S L +P  V +   
Sbjct: 176 LEELEKATGISKKDIA---KAYRLIVRELGIKPKPISPADFVYRYASELNLPPEVTATAI 232

Query: 246 QVARAAAEKDGIHGR 260
           ++   A +K+ + GR
Sbjct: 233 EIIEEAKKKNIVSGR 247

ref|NP_614141.1| Transcription initiation factor IIB [Methanopyrus kandleri AV19]
gb|AAM02071.1| Transcription initiation factor IIB [Methanopyrus kandleri AV19]
sp|Q8TX21|TF2B_METKA Transcription initiation factor IIB (TFIIB)
(307 aa)

Score: 84 bits (207), Expect: 4.58165e-15
Length: 298, Idn/Pos/Gap = 78/136/23 (26%/45%/7%)

Query:  14 CGECGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSIN-P  72
           C  CGS ++V D + G+ VCA CG+V  + +ID G EWR F N D     +R G  +   
Sbjct:  15 CPACGSAEIVFDEERGEYVCANCGLVTEDPVIDPGPEWRHF-NPDQRQRRSRTGEPVKLR  73

Query:  73 LLDSGLATSISQGPAGANA-LNERLARAQSRN----VLDANDRYVTECYNRISYLCERSG 127
           L D G++T I +    +    N R+ R ++ +    V  + +R   + +  +  L  +  
Sbjct:  74 LPDKGISTIIDRELRDSGGKKNPRMRRIRTWDARIKVSGSRERNFFQAFLELENLASKLQ 133

Query: 128 LPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRTFN 187
           LP+ V++ A  + R  Y    +   G+            S++ AA+F AC+    PRT  
Sbjct: 134 LPESVRELAASIYRKAYKEGIVRGRGIE-----------SVLGAAVFAACKEARVPRTAR 182

Query: 188 EISVIVSVA-KSRVAAYVKAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPNIVRSLVNQ 246
           EI+  + V+ ++ +    + ++  +    K +      D + RF S L +   V++   +
Sbjct: 183 EIAEALGVSDENEILRAYRVLQRRLNLKQKPTE---PSDHLPRFASKLGVSENVQAKAQE 239

Query: 247 VARAAAEKDGIHGRTLVSIAAGAIYFVLLLWRETCPQ-SIPATLRVSDEALVNRIAEV 303
           +   A EK    G+    +AA A+Y   +L  E   Q  I    RV++  + NR  E+
Sbjct: 240 IIEKAKEKGITVGKGPAGVAAAALYIASILEGERRTQKEIAEVARVTEVTIRNRYKEI 297

ref|ZP_00307442.1| COG1405: Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB [Ferroplasma acidarmanus]
(305 aa)

Score: 83 bits (206), Expect: 7.12977e-15
Length: 259, Idn/Pos/Gap = 74/119/26 (28%/45%/10%)

Query:   6 MERDVPDVCGECGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNR  65
           M+ D    C ECGS  LV+D   G+L C  CG+V  + LID G EWR F+++      +R
Sbjct:   1 MKTDEVKNCPECGSIHLVKDYDRGELTCYDCGIVIEDSLIDQGPEWRAFDSEQDG-KRSR  59

Query:  66 VGGSINPLL-DSGLATSISQG---------PAGANALNERLARAQSR-NVLDANDRYVTE 114
            G  ++ L  D GLAT IS           P    +   R+ +   R  V +A +R +  
Sbjct:  60 TGSPMSFLSHDKGLATEISWSNKDYYGKRIPHKNRSQIYRVRKWHQRIRVSNAAERNLAL 119

Query: 115 CYNRISYLCERSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALF 174
               ++    + G+P+ +K+ A  + R       +  + +R R+        SI+ A+++
Sbjct: 120 ALQVLNEDGAKLGIPKDIKESAALIYR-----KAVEKNLIRGRS------IESIVCASIY 168

Query: 175 IACRNEGFPRTFNEISVIVSVAKSRVAAYVKAMEMSIGEAAKISRIRTTDDFVSRFCSYL 234
            +CR    PRT +EIS +  V K ++    KA      E A   +  T   +VS+FC+ L
Sbjct: 169 ASCRMINIPRTLDEISKVSEVNKKKIG---KAYRHLAKELALNLQPTTPYSYVSQFCNKL 225

Query: 235 EIPNIVRSLVNQVARAAAE 253
           ++   V      + R A E
Sbjct: 226 DLDKQVIMDSEHIIRLAGE 244

ref|NP_111608.1| Transcription initiation factor IIB [Thermoplasma volcanium GSS1]
dbj|BAB60255.1| transcription initiation factor B [TFB] [Thermoplasma volcanium GSS1]
sp|Q979P7|TF2B2_THEVO Transcription initiation factor IIB 2 (TFIIB 2)
(313 aa)

Score: 82 bits (202), Expect: 2.18094e-14
Length: 257, Idn/Pos/Gap = 69/117/26 (26%/45%/10%)

Query:   6 MERDVPDVCGECGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNR  65
           +E + P  C EC S  L+ D ++G+L+CA CG V  +  ID G EWR F++D       R
Sbjct:   9 IESEAPKRCPECHSEHLIRDYEHGELICADCGAVIEDSFIDQGPEWRAFDSDQDERRA-R  67

Query:  66 VGGSINPLL-DSGLATSISQG---------PAGANALNERLARAQSR-NVLDANDRYVTE 114
            G  +  L  D GLAT IS           P    A   R+ +   R  V +A +R ++ 
Sbjct:  68 TGSPMTYLSHDKGLATEISWSNKDYYGKRIPHKNRAQIYRVRKWHQRIRVSNAAERNLSL 127

Query: 115 CYNRISYLCERSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALF 174
               ++ +  + G+P+ +K+ +  + R       +  + +R R+        SI+ A+++
Sbjct: 128 ALQLLNDIGAKLGIPKDIKETSALIYR-----KAVEKNLIRGRS------IESIVCASIY 176

Query: 175 IACRNEGFPRTFNEISVIVSVAKSRVAAYVKAMEMSIGEAAKISRIRTTDDFVSRFCSYL 234
            ACR    PRT +EI+    V K ++    KA      E     R  T   ++++FC+ L
Sbjct: 177 AACRKVNIPRTLDEIAKASEVNKKKIG---KAYRHLAKELDLNLRPTTPFSYIAQFCNKL 233

Query: 235 EIPNIVRSLVNQVARAA 251
           ++      +   + R A
Sbjct: 234 DLDKQAIVISEDIVRQA 250

ref|NP_377204.1| hypothetical transcription initiation factor IIB [Sulfolobus tokodaii str. 7]
dbj|BAB66313.1| 295aa long hypothetical transcription initiation factor IIB [Sulfolobus tokodaii str. 7]
(295 aa)

Score: 81 bits (200), Expect: 3.28248e-14
Length: 297, Idn/Pos/Gap = 68/130/24 (22%/43%/8%)

Query:  14 CGECGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSINPL  73
           C  CGS  +  D   G  +C  CG V  E +ID G EWR +   D   +  R G  I   
Sbjct:   6 CPNCGSESITLDLNKGTYICTNCGYVIDEFVIDQGPEWRAYTEQDR-LERERTGSPITAK  64

Query:  74 L-DSGLATSISQGPAGANALNERLARAQSRNVLDANDRYVTECYNRISYLCERSGLPQLV 132
           + D G+ T+I    +      E+L   Q++  +   DR +    + ++    +  LP+ V
Sbjct:  65 VHDFGITTTIGYSRSSNKTKIEKLRAIQNKLRVSPKDRKLVTYLSVLNNEAAKLNLPEYV 124

Query: 133 KDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRTFNEISVI 192
           K+ A  L+R   D             + +  +  ++I+A L+ +C+    P++  EI   
Sbjct: 125 KETASLLIRKIID-----------EGKAKRIDIYTLIAAVLYYSCQVNKIPKSLQEIKNN 173

Query: 193 VSVAKSRVAAYVKAMEMSIGEAAKIS-----RIRTTDDFVSRFCSYLEIPNIVRSLVNQV 247
             ++ S +    KA+E  + + AK S      I+ T +F+ +    L +P  + +  +++
Sbjct: 174 YGISSSELW---KALE-RVQKVAKSSLEFKPNIKPT-EFIPKIVEKLNLPPYISTKASEL 228

Query: 248 ARAAAEKDGIHGRTLVSIAAGAIYFV-LLLWRETCPQSIPATLRVSDEALVNRIAEV 303
                +     G+   ++AA ++Y V  L+  +   + I   L +++  + NR  E+
Sbjct: 229 VDLMHKNGLTSGKGYTALAAASVYLVSTLMDAKKTQKDIANALNITEVTIRNRYKEI 285

dbj|BAD86476.1| transcription initiation factor IIB [Thermococcus kodakaraensis KOD1]
ref|YP_184700.1| transcription initiation factor IIB [Thermococcus kodakaraensis KOD1]
sp|P58109|TF2B_PYRKO Transcription initiation factor IIB (TFIIB) (Tk-TFB)
dbj|BAB21262.1| Tk-TFB [Thermococcus kodakaraensis]
(306 aa)

Score: 81 bits (200), Expect: 3.68921e-14
Length: 259, Idn/Pos/Gap = 67/112/26 (25%/43%/10%)

Query:  13 VCGECGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSINP  72
           VC  CGST+ + D + G++VCA+CG V  E ++D G EWR FE         R G  +  
Sbjct:   9 VCPICGSTEFIYDPRRGEIVCAKCGYVIEENVVDEGPEWRAFEPGQREKRA-RTGAPMTL  67

Query:  73 LL-DSGLATSIS------QGPAGANALNERLAR----AQSRNVLDANDRYVTECYNRISY 121
           ++ D GL+T I        G         +L R     +   + DA +R +    + +  
Sbjct:  68 MIHDKGLSTDIDWRDKDIHGNQITGMYRNKLRRLRMWQRRMRINDAAERNLAFALSELDR 127

Query: 122 LCERSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEG 181
           +  +  LP+ +K+ A  L R               +   R      ++SAAL+ ACR EG
Sbjct: 128 MAAQLRLPRHLKEVAASLYR-----------KAVMKKLIRGRSIEGMVSAALYAACRMEG 176

Query: 182 FPRTFNEISVIVSVAKSRVAAYVKAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPNIVR 241
            PRT +EI+ +  V+K  +    + M   +G      R  +  ++V RF   L +    +
Sbjct: 177 IPRTLDEIASVSKVSKKEIGRSYRFMARGLGLNL---RPTSPIEYVDRFGDALGVSARTK 233

Query: 242 SLVNQVARAAAEKDGIHGR 260
               ++   A ++    G+
Sbjct: 234 KRAKEILNEAIKRGITSGK 252

gb|AAV46288.1| transcription initiation factor IIB [Haloarcula marismortui ATCC 43049]
ref|YP_135994.1| transcription initiation factor IIB [Haloarcula marismortui ATCC 43049]
(324 aa)

Score: 80 bits (197), Expect: 8.56883e-14
Length: 308, Idn/Pos/Gap = 85/148/38 (27%/48%/12%)

Query:  13 VCGECGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGG-SIN  71
           VC EC S  L+ D++ G+ VC  CG+V  E  ID G EWR F++ +   + +RVG  + N
Sbjct:  29 VCPEC-SGALLSDSERGETVCEDCGLVVEEDEIDPGPEWRAFDSKEKD-EKSRVGAPTTN  86

Query:  72 PLLDSGLATSI------SQGPAGANALNERLARAQSRN----VLDANDRYVTECYNRISY 121
            + D GL+T+I      + G + ++   E++ R ++ N      D+ +R + +    I  
Sbjct:  87 MMHDKGLSTNIGWQDKDAYGNSLSSRQREKMQRLRTWNERFRTRDSKERNLKQALGEIDR 146

Query: 122 LCERSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEG 181
           +    GLP+ V++ A  + R   D   L    +             + +A+L+ A R  G
Sbjct: 147 MASALGLPENVRETASVIYRRALDEDLLPGRSIEG-----------VSTASLYAAARQAG 195

Query: 182 FPRTFNEISVIVSVAKSRVAA----YVKAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIP 237
            PR+ +EI+ +  V K  +A      V+ + + I  A         + +V RF S L++ 
Sbjct: 196 TPRSLDEIAGVSRVEKDEIARTYRYVVRELSLEIQPA-------DPESYVPRFASDLDLS 248

Query: 238 NIVRSLVNQVARAAAEKDGIH-GRTLVSIAAGAIYFVLLLWRETCPQS-IPATLRVSDEA 295
             V     Q+ +  A+++G+H G++ V +AA A+Y   LL  E   QS +     +S+  
Sbjct: 249 EEVERRARQLLQ-NAKQEGVHSGKSPVGLAAAAVYAASLLTNEKVTQSQVSEVANISEVT 307

Query: 296 LVNRIAEV 303
           + NR  E+
Sbjct: 308 IRNRYHEL 315

gb|AAU83853.1| transcription initiation factor IIB [uncultured archaeon GZfos34G5]
(306 aa)

Score: 79 bits (194), Expect: 1.64273e-13
Length: 233, Idn/Pos/Gap = 66/107/32 (28%/45%/13%)

Query:  14 CGECGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSIN-P  72
           C ECGS +++ D+++ +L CA CG+V AE ++DLG EWR+++ ++ A    R G  ++  
Sbjct:  15 CPECGSKNVITDSRHAELYCADCGIVIAENIVDLGPEWRSYD-EEQASKRIRTGPPMSYR  73

Query:  73 LLDSGLATSISQGPAGANALNERLARAQSRNVLDANDRYVTECYNRISYLCERSGLPQLV 132
           + D GL T     PA       R  R  S   +D++D+ +      I  +    GLP  +
Sbjct:  74 IHDKGLGTPTPGLPA-----RTRRLRGIS---IDSSDKTLAFALVEIDRMACALGLPNNI 125

Query: 133 KDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRTFNEIS-V 191
           K+    L R               R   +      ++SA L+I CR  G PRT  E++ V
Sbjct: 126 KEATSVLYR-----------KAMKRGLIKGRSIEELVSAMLYITCRQYGVPRTLKEMAEV 174

Query: 192 IVSVAKSRVAAYV---KAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPNIVR 241
             S  K    AY+   + +E+ +  A           ++ RFCS L +   +R
Sbjct: 175 SRSPLKKIRRAYIFLLRRLEIKLAPADPAR-------YIPRFCSKLGLSAEIR 220

ref|NP_615574.1| archaeal transcription factor B [Methanosarcina acetivorans C2A]
gb|AAM04054.1| archaeal transcription factor B [Methanosarcina acetivorans str. C2A]
sp|Q8TT29|TF2B_METAC Transcription initiation factor IIB (TFIIB)
(337 aa)

Score: 78 bits (193), Expect: 2.07505e-13
Length: 259, Idn/Pos/Gap = 78/125/26 (30%/48%/10%)

Query:  13 VCGECGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSIN-  71
           VC ECGS +LV D +  +LVC  CG+V     +D G EWR F++D      +RVG  +  
Sbjct:  40 VCPECGSRNLVHDYERAELVCGDCGLVIDADFVDEGPEWRAFDHDQRM-KRSRVGAPMTY  98

Query:  72 PLLDSGLATSI------SQGPAGAN---ALNERLARAQSR-NVLDANDRYVTECYNRISY 121
            + D GL+T I      S G + ++   A   RL + Q R  V +A +R +    + +  
Sbjct:  99 TIHDKGLSTMIDWRNRDSYGKSISSKNRAQLYRLRKWQRRIRVSNATERNLAFALSELDR 158

Query: 122 LCERSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEG 181
           +    GLP+ V++ A  + R   D      + +R R+         + +AAL+ ACR   
Sbjct: 159 MASALGLPRTVRETAAVVYRKAVDK-----NLIRGRS------IEGVAAAALYAACRQCS 207

Query: 182 FPRTFNEISVIVSVAKSRVAAYVKAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPNIVR 241
            PRT +EI  +  V++  +    + +   +  A K+       D+V RFCS L +   V+
Sbjct: 208 VPRTLDEIEEVSRVSRKEIGRTYRFISREL--ALKLMPTSPI-DYVPRFCSGLNLKGEVQ 264

Query: 242 SLVNQVARAAAEKDGIHGR 260
           S   ++ R A+EK+   GR
Sbjct: 265 SKSVEILRQASEKELTSGR 283

ref|ZP_00295754.1| COG1405: Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB [Methanosarcina barkeri str. fusaro]
(337 aa)

Score: 78 bits (193), Expect: 2.10996e-13
Length: 259, Idn/Pos/Gap = 78/125/26 (30%/48%/10%)

Query:  13 VCGECGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSIN-  71
           VC ECGS +LV D +  +LVC  CG+V     +D G EWR F++D      +RVG  +  
Sbjct:  40 VCPECGSRNLVHDYERAELVCGDCGLVIDADFVDEGPEWRAFDHDQRM-KRSRVGAPMTY  98

Query:  72 PLLDSGLATSI------SQGPAGAN---ALNERLARAQSR-NVLDANDRYVTECYNRISY 121
            + D GL+T I      S G + ++   A   RL + Q R  V +A +R +    + +  
Sbjct:  99 TIHDKGLSTMIDWRNRDSYGKSISSKNRAQLYRLRKWQRRIRVSNATERNLAFALSELDR 158

Query: 122 LCERSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEG 181
           +    GLP+ V++ A  + R   D      + +R R+         + +AAL+ ACR   
Sbjct: 159 MASALGLPRTVRETAAVVYRKAVDK-----NLIRGRS------IEGVAAAALYAACRQCS 207

Query: 182 FPRTFNEISVIVSVAKSRVAAYVKAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPNIVR 241
            PRT +EI  +  V++  +    + +   +  A K+       D+V RFCS L +   V+
Sbjct: 208 VPRTLDEIEEVSRVSRKEIGRTYRFISREL--ALKLMPTSPI-DYVPRFCSGLNLKGEVQ 264

Query: 242 SLVNQVARAAAEKDGIHGR 260
           S   ++ R A+EK+   GR
Sbjct: 265 SKSVEILRQASEKELTSGR 283

ref|NP_633796.1| Transcription initiation factor IIB [Methanosarcina mazei Go1]
emb|CAC42919.1| transcription factor B (TFB) [Methanosarcina mazei]
gb|AAM31468.1| Transcription initiation factor IIB [Methanosarcina mazei Goe1]
sp|Q977U3|TF2B_METMA Transcription initiation factor IIB (TFIIB)
(337 aa)

Score: 78 bits (193), Expect: 2.25561e-13
Length: 259, Idn/Pos/Gap = 78/125/26 (30%/48%/10%)

Query:  13 VCGECGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSIN-  71
           VC ECGS +LV D +  +LVC  CG+V     +D G EWR F++D      +RVG  +  
Sbjct:  40 VCPECGSRNLVHDYERAELVCGDCGLVIDADFVDEGPEWRAFDHDQRM-KRSRVGAPMTY  98

Query:  72 PLLDSGLATSI------SQGPAGAN---ALNERLARAQSR-NVLDANDRYVTECYNRISY 121
            + D GL+T I      S G + ++   A   RL + Q R  V +A +R +    + +  
Sbjct:  99 TIHDKGLSTMIDWRNRDSYGKSISSKNRAQLYRLRKWQRRIRVSNATERNLAFALSELDR 158

Query: 122 LCERSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEG 181
           +    GLP+ V++ A  + R   D      + +R R+         + +AAL+ ACR   
Sbjct: 159 MASALGLPRTVRETAAVVYRKAVDK-----NLIRGRS------IEGVAAAALYAACRQCS 207

Query: 182 FPRTFNEISVIVSVAKSRVAAYVKAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPNIVR 241
            PRT +EI  +  V++  +    + +   +  A K+       D+V RFCS L +   V+
Sbjct: 208 VPRTLDEIEEVSRVSRKEIGRTYRFISREL--ALKLMPTSPI-DYVPRFCSGLNLKGEVQ 264

Query: 242 SLVNQVARAAAEKDGIHGR 260
           S   ++ R A+EK+   GR
Sbjct: 265 SKSVEILRQASEKELTSGR 283

gb|EAK89316.1| transcription initiation factor TFIIB Sua7p; ZnR+2cyclins [Cryptosporidium parvum]
(456 aa)

Score: 78 bits (191), Expect: 3.56915e-13
Length: 264, Idn/Pos/Gap = 67/126/25 (25%/47%/9%)

Query:  14 CGECGSTD--LVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSIN  71
           C  CG+ +  +V D+K+G  +C +CGVV  + +I+   EWR+F ND +  +     GS+N
Sbjct: 152 CKRCGAGNSIVVYDSKSGSEICTRCGVVVEDRVINEEQEWRSFSNDGNDGNSKSRIGSVN 211

Query:  72 PL-LDSGLATSISQGPAGANALNERLARAQSRNVLDANDRYVTECYNRISYLCERSGLPQ 130
            + LD G   + SQ   G   L + + +    N   ++DR + E +N++  +     L  
Sbjct: 212 DVWLDDG---TDSQLLVGDKKLMKTMLK---HNTQASSDRMIKEVFNQLRQIANSFSLHD 265

Query: 131 LVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRTFNE-I 189
            + +R  E+++    +L +   G +             + A +++ACR EG  RT  E +
Sbjct: 266 NIIERCKEIVK-EQSNLNILKSGKKH------------VLAIVYLACREEGVSRTVKELL 312

Query: 190 SVIVSVAKSRVAAYVKAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPNIVRSLVNQVAR 249
           S   ++++  +   +  ++  +      +   +  + + RFC YL++ + +  +   V R
Sbjct: 313 SFDRTISERELVRSINKLKKDLPRRGP-TLSSSAAELMPRFCHYLQLSHEIVGIAEYVCR 371

Query: 250 AAAEKDGIHGRTLVSIAAGAIYFV 273
            A +      R   S+AAGAIYFV
Sbjct: 372 TAEQYINKSHRP-NSLAAGAIYFV 394

gb|AAV47530.1| transcription initiation factor IIB [Haloarcula marismortui ATCC 43049]
ref|YP_137236.1| transcription initiation factor IIB [Haloarcula marismortui ATCC 43049]
(286 aa)

Score: 78 bits (191), Expect: 3.91223e-13
Length: 263, Idn/Pos/Gap = 66/110/24 (25%/41%/9%)

Query:  14 CGECGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSIN-P  72
           C EC  +   +  ++   VC  CG+V  E  ID G EWR+FE+DD+  D  R G  +   
Sbjct:   8 CPECNGSVKQQGVES---VCGSCGLVVGEDAIDPGPEWRSFEDDDT--DRARTGAPLTRS  62

Query:  73 LLDSGLATSISQGPAGANALNERLARAQSRN----VLDANDRYVTECYNRISYLCERSGL 128
             D GL+T I +          + AR +  +    +    +R     +  I  +     L
Sbjct:  63 RHDRGLSTKIGRSTRLKGRKRRQFARLRREHNRAQISSKRERNKVYAFTEIRRIISSMAL 122

Query: 129 PQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRTFNE 188
              ++DRAC L     +   L    +   A           +AA++  CR EG  RT +E
Sbjct: 123 SDAIRDRACVLFESAQNEDLLQGRTLEGFA-----------AAAIYATCRTEGVARTVDE 171

Query: 189 ISVIVSVAKSRVAAYVKAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPNIVRSLVNQVA 248
           +  +    ++ + A   A+   +G        R   ++V RF + L++P  VR    Q+ 
Sbjct: 172 LCTVAKATQAELRAAYDALNRELGLPTGPIDPR---EYVPRFATTLDLPTAVRQRAEQLV 228

Query: 249 RAAAEKDGIHGRTLVSIAAGAIY 271
             A ++  + GR    +AA  +Y
Sbjct: 229 DEAQDRGLVSGRNPAGVAAACLY 251

gb|AAV45101.1| transcription initiation factor IIB [Haloarcula marismortui ATCC 43049]
ref|YP_134807.1| transcription initiation factor IIB [Haloarcula marismortui ATCC 43049]
(319 aa)

Score: 77 bits (189), Expect: 7.19367e-13
Length: 331, Idn/Pos/Gap = 91/139/49 (27%/41%/14%)

Query:   1 MSAPTMERDVP-------------DVCGECGSTDLVEDTKNGDLVCAQCGVVAAELLIDL  47
           M  PT +RD                 C EC S  +  D   G+LVC  CG+V  +  ID 
Sbjct:   1 MERPTRQRDSEQEEREEESESTGQQTCPECESESISSD-GGGELVCEDCGLVIEDENIDR  59

Query:  48 GHEWRTFENDDSAYDPNRVGG-SINPLLDSGLATSISQGPAGANALN---------ERLA  97
           G EWR F N       +RVG  +   + D GL T I      A   +          RL 
Sbjct:  60 GPEWRAF-NHSERQSKSRVGAPTTQTMHDKGLTTQIDWKDKDAYGRSLSSEKRSQMHRLR 118

Query:  98 RAQSR-NVLDANDRYVTECYNRISYLCERSGLPQLVKDRACELLRLYYDHLTLGADGVRA 156
           + Q R    DA +R +    + I  +    G+P+ V++ A  + R       L  D +R 
Sbjct: 119 KWQERIRTKDAGERNLQFALSEIDRMASALGVPRSVREVASVIYRR-----ALNEDLIRG 173

Query: 157 RARFREDETASIISAALFIACRNEGFPRTFNEISVIVSVAKSRVAAYVK--AMEMSIGEA 214
           R+         + +A L+ ACR EG PR+  E+S +  V +  +    +  A E+ +   
Sbjct: 174 RS------IEGVATACLYAACRQEGIPRSLEEVSDVSRVEQKEIGRTYRYVAQELEL--- 224

Query: 215 AKISRIRTTD--DFVSRFCSYLEIPNIVRSLVNQVARAAAEKDGIHGRTLVSIAAGAIYF 272
               ++   D   +V RF S LE+   V+S  N++    AE+  + G++    AA AIY 
Sbjct: 225 ----KMEPVDPKQYVPRFASELELSEEVQSKANEIIDTTAEQGLLSGKSPTGYAAAAIYA 280

Query: 273 VLLLWRETCPQ-SIPATLRVSDEALVNRIAE 302
             LL  E   Q  +    +V++  + NR  E
Sbjct: 281 ASLLCNEKKTQREVADVAQVTEVTIRNRYQE 311

ref|ZP_00147699.1| COG1405: Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB [Methanococcoides burtonii DSM 6242]
(337 aa)

Score: 75 bits (185), Expect: 1.65697e-12
Length: 260, Idn/Pos/Gap = 79/127/30 (30%/48%/11%)

Query:  14 CGECGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSIN-P  72
           C ECGS  L +D +  +LVCA CG+V     +D G EWR F++D      +RVG  +   
Sbjct:  41 CPECGSRSLEQDYERAELVCADCGLVVDAEFVDEGPEWRAFDHDQRM-KRSRVGAPMTYT  99

Query:  73 LLDSGLATSI------SQGPAGAN---ALNERLARAQSR-NVLDANDRYVTECYNRISYL 122
           + D GL+T I      S G + ++   A   RL + Q R  V +A +R +    + +  +
Sbjct: 100 IHDKGLSTMIDWRNRDSYGKSISSKNRAQLYRLRKWQRRIRVSNATERNLAFALSELDRM 159

Query: 123 CERSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGF 182
               GLP+ V++ A  + R   D      + +R R+         + +AAL+ ACR    
Sbjct: 160 ASALGLPRTVRETAAVVYRKAVDK-----NLIRGRS------IEGVAAAALYAACRQCSV 208

Query: 183 PRTFNEISVIVSVAKSRVAAYVK--AMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPNIV 240
           PRT +EI  +  V++  +    +  + E+S+ +    S I    D+V RFCS L +   V
Sbjct: 209 PRTLDEIGEVSRVSRKEIGRTYRFISRELSL-KLMPTSPI----DYVPRFCSGLNLKGEV 263

Query: 241 RSLVNQVARAAAEKDGIHGR 260
           +S   ++ R A+EK+   GR
Sbjct: 264 QSRGVEILRQASEKELTSGR 283

ref|NP_279732.1| TfbB [Halobacterium sp. NRC-1]
gb|AAG19212.1| transcription initiation factor IIB; TfbB [Halobacterium sp. NRC-1]
pir||H84230 transcription initiation factor IIB [imported] - Halobacterium sp. NRC-1
sp|Q9HRE6|TF2B2_HALN1 Transcription initiation factor IIB 2 (TFIIB 2)
(325 aa)

Score: 75 bits (185), Expect: 1.97429e-12
Length: 313, Idn/Pos/Gap = 85/145/38 (27%/46%/12%)

Query:  14 CGECGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGG-SINP  72
           C ECG   +++D ++G+ VC  CG+V  E  ID G EWR F N     + +RVG  + N 
Sbjct:  32 CPECGG-QVIDDEEHGESVCVDCGLVVEENGIDRGPEWRAF-NSTEKDEKSRVGAPTTNM  89

Query:  73 LLDSGLATSI--SQGPAGANALN-------ERLARAQSR-NVLDANDRYVTECYNRISYL 122
           + D GL+T+I      A  N+L+       +RL +   R    ++ +R + +    I  +
Sbjct:  90 MHDKGLSTNIGWQDKDAYGNSLSSNQRQKMQRLRKWNERFRTRNSKERNLKQALGEIERM 149

Query: 123 CERSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGF 182
               GLP+ V++ A  + R       L  D +  R+         + +AAL+ + R    
Sbjct: 150 ASALGLPKEVRETASVIYR-----RALSEDLLPGRS------IEGVATAALYASARQLST 198

Query: 183 PRTFNEISVIVSVAK---SRVAAY-VKAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPN 238
           PR+ +E++ +  + +    R   Y V+ + + +  A           +V RF S L++P+
Sbjct: 199 PRSIDEVANVSRIDEMEFKRTYRYIVRELSLEVAPA-------DPAQYVPRFASDLDLPD 251

Query: 239 IVRSLVNQVARAAAEKDGI-HGRTLVSIAAGAIYFVLLLWRETCPQS-IPATLRVSDEAL 296
            V     ++  + A+ DG+  G++ V +AA AIY   LL      QS +     VS+  +
Sbjct: 252 EVERRSRELI-SNAQADGVTSGKSPVGLAAAAIYASSLLTNHKVTQSEVSEVTDVSEVTI 310

Query: 297 VNRIAEVSGITEG 309
            NR  E+   TE 
Sbjct: 311 RNRYQELLEATEA 323

gb|AAV46756.1| transcription initiation factor IIB [Haloarcula marismortui ATCC 43049]
ref|YP_136462.1| transcription initiation factor IIB [Haloarcula marismortui ATCC 43049]
(321 aa)

Score: 75 bits (184), Expect: 2.53584e-12
Length: 256, Idn/Pos/Gap = 71/119/28 (27%/46%/10%)

Query:  14 CGECGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGG-SINP  72
           C EC S  LV D ++G+ VC  CG+V     ID G EWR F++ +   + +RVG  + N 
Sbjct:  26 CPEC-SGSLVIDDEHGETVCEDCGLVVESDEIDRGPEWRAFDSSEKD-EKSRVGAPTTNM  83

Query:  73 LLDSGLATSIS--QGPAGANALN-------ERLARAQSR-NVLDANDRYVTECYNRISYL 122
           + D GL+T+I      A  N+L+       +RL +   R    D+ +R + +    I  +
Sbjct:  84 MHDKGLSTNIDWRDKDAYGNSLSGKQRQKMQRLRKWNERFRTRDSKERNLKQALGEIDRM 143

Query: 123 CERSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGF 182
               GLP+ V++ A  + R   D   L    +             + +A+++ A R  G 
Sbjct: 144 ASALGLPENVRETASVIYRRALDEDLLPGRSIEG-----------VSTASVYAAARQAGV 192

Query: 183 PRTFNEISVIVSVAKSRVAAYVKAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPNIVRS 242
           PR+ +EI+ +  V KS +A   +     + E +   R    + +V RF S LE+ +    
Sbjct: 193 PRSLDEITEVSRVEKSEIA---RTYRYVVRELSLEVRPADPESYVPRFASSLELSDEAEH 249

Query: 243 LVNQVARAAAEKDGIH 258
              Q+ + A E+ G+H
Sbjct: 250 RARQLLQNAKEQ-GVH 264

ref|NP_341982.1| Transcription initiation factor IIB (TFIIB) homolog (TFB-1) [Sulfolobus solfataricus P2]
gb|AAK40772.1| Transcription initiation factor IIB (TFIIB) homolog (TFB-1) [Sulfolobus solfataricus P2]
sp|P58111|TF2B1_SULSO Transcription initiation factor IIB 1 (TFIIB 1)
pir||E90189 hypothetical protein TFB-1 [imported] - Sulfolobus solfataricus
(309 aa)

Score: 75 bits (183), Expect: 3.453e-12
Length: 320, Idn/Pos/Gap = 77/132/42 (24%/41%/13%)

Query:  13 VCGECGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSINP  72
           V   C    ++ D + G+ +C++ G V  + +ID G EWR F  ++     +RVGG +N 
Sbjct:  11 VSTPCPPDKIIFDAERGEYICSETGEVLEDKIIDQGPEWRAFTPEEKE-KRSRVGGPLNN  69

Query:  73 LL-DSGLATSISQGPAGA-----------NALNERLARAQSRNVLDANDRYVTECYNRIS 120
            + D GL+T I      A            AL  R  + ++R +  + DR + +  N + 
Sbjct:  70 TIHDRGLSTLIDWKDKDAMGRTLDPKRRLEALRWRKWQIRAR-IQSSIDRNLAQAMNELE 128

Query: 121 YLCERSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNE 180
            +     LP+ VKD A  + R   +           +   R     S+++AA++ ACR  
Sbjct: 129 RIGNLLNLPKSVKDEAALIYRKAVE-----------KGLVRGRSIESVVAAAIYAACRRM 177

Query: 181 GFPRTFNEISVIVSVAKSRVAAYVKAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPNIV 240
              RT +EI+      +  VA   + +   +  +  +S  +   D+V+R  + L +   V
Sbjct: 178 KLARTLDEIAQYTKANRKEVARCYRLLLRELDVSVPVSDPK---DYVTRIANLLGLSGAV 234

Query: 241 RSLVNQVARAAAEKDGIHGRTLVSIAAGAIYFVLLLWRETCPQSIPATLRVSDEALVNRI 300
                ++   A       G+    +AA AIY   LL  E   Q                I
Sbjct: 235 MKTAAEIIDKAKGSGLTAGKDPAGLAAAAIYIASLLHDERRTQ--------------KEI 280

Query: 301 AEVSGITEGVVKTVASRIRQ 320
           A+V+G+TE  V+     + Q
Sbjct: 281 AQVAGVTEVTVRNRYKELTQ 300

pir||T46894 transcription factor TFIIB homolog TFB [imported] - Sulfolobus shibatae
gb|AAA81380.1| transcription factor TFIIB homolog
sp|P50387|TF2B_SULSH Transcription initiation factor IIB (TFIIB)
(309 aa)

Score: 74 bits (181), Expect: 5.79245e-12
Length: 320, Idn/Pos/Gap = 77/132/42 (24%/41%/13%)

Query:  13 VCGECGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSINP  72
           V   C    ++ D + G+ +C++ G V  + +ID G EWR F  ++     +RVGG +N 
Sbjct:  11 VSTPCPPDKIIFDAERGEYICSETGEVLEDKIIDQGPEWRAFTPEEKE-KRSRVGGPLNN  69

Query:  73 LL-DSGLATSISQGPAGA-----------NALNERLARAQSRNVLDANDRYVTECYNRIS 120
            + D GL+T I      A            AL  R  + ++R +  + DR + +  N + 
Sbjct:  70 TIHDRGLSTLIDWKDKDAMGRTLDPKRRLEALRWRKWQIRAR-IQSSIDRNLAQAMNELE 128

Query: 121 YLCERSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNE 180
            +     LP+ VKD A  + R   +           +   R     S+++AA++ ACR  
Sbjct: 129 RIGNLLNLPKSVKDEAALIYRKAVE-----------KGLVRGRSIESVVAAAIYAACRRM 177

Query: 181 GFPRTFNEISVIVSVAKSRVAAYVKAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPNIV 240
              RT +EI+      +  VA   + +   +  +  +S  +   D+V+R  + L +   V
Sbjct: 178 KLARTLDEIAQYTKANRKEVARCYRLLLRELDVSVPVSDPK---DYVTRIANLLGLSGRV 234

Query: 241 RSLVNQVARAAAEKDGIHGRTLVSIAAGAIYFVLLLWRETCPQSIPATLRVSDEALVNRI 300
                ++   A       G+    +AA AIY   LL  E   Q                I
Sbjct: 235 MKTAAEIIDKAKGSGLTAGKDPAGLAAAAIYIASLLHDERRTQ--------------KEI 280

Query: 301 AEVSGITEGVVKTVASRIRQ 320
           A+V+G+TE  V+     + Q
Sbjct: 281 AQVAGVTEVTVRNRYKELTQ 300

ref|NP_395840.1| TfbC [Halobacterium sp. NRC-1]
gb|AAG20975.1| transcription initiation factor IIB; TfbC [Halobacterium sp. NRC-1]
sp|Q9HHK5|TF2B3_HALN1 Transcription initiation factor IIB 3 (TFIIB 3)
(317 aa)

Score: 73 bits (179), Expect: 9.01395e-12
Length: 269, Idn/Pos/Gap = 73/120/38 (27%/44%/14%)

Query:   9 DVPDVCGECGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGG  68
           D    C EC S +++ D    + VC  CG+V  +  ID G EWR F N       +RVG 
Sbjct:  20 DEAQQCPECNSANVITD--QSERVCEDCGLVLEDDQIDHGPEWRAF-NSSERDQKSRVGA  76

Query:  69 -SINPLLDSGLATSISQGPAGA----------NALNERLARAQSR-NVLDANDRYVTECY 116
            +   + D GL T I      A          N +N RL + Q R    DA +R +    
Sbjct:  77 PTTKTMHDKGLTTQIDWKDKDAYGRSLDAKKRNQMN-RLRKWQERIRTKDAGERNLQFAL 135

Query: 117 NRISYLCERSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIA 176
           + I  +    G+P+ V++ A  + R       L  D +R R+         + +A L+ A
Sbjct: 136 SEIDRMASALGVPRSVREVASVIYRR-----ALKEDLIRGRS------IEGVATACLYAA 184

Query: 177 CRNEGFPRTFNEISVIVSVAKSRVAAYVK--AMEMSIGEAAKISRIRTTD--DFVSRFCS 232
           CR EG PRT  E++ +  + +  +    +  A E+S+        I+ TD  +++ RF S
Sbjct: 185 CRQEGIPRTLEEVTEVARIDQKEIGRTYRYVAQELSL-------EIQPTDPKEYLPRFAS 237

Query: 233 YLEIPNIVRSLVNQVARAAAEKDGIHGRT 261
            LE+   V +   ++   +AE+  + G++
Sbjct: 238 DLELSEEVIAKAREIIDTSAEQGLLSGKS 266

gb|AAD43074.1| transcription factor B [Haloferax volcanii]
sp|Q9YGA5|TFB2_HALVO Transcription initiation factor IIB 2 (TFIIB 2)
pir||T44261 transcription initiation factor IIB [imported] - Haloferax volcanii
(332 aa)

Score: 73 bits (178), Expect: 1.36804e-11
Length: 322, Idn/Pos/Gap = 87/155/38 (27%/48%/11%)

Query:   7 ERDVPDVCGECGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRV  66
           ++D   VC EC S  LV D ++G+ +C  CG+V  + ++D G EWR F++ +     +RV
Sbjct:  30 QQDETQVCPEC-SGHLVTDEEHGETICEDCGLVVEDTVVDRGPEWRAFDSAERD-SKSRV  87

Query:  67 GGSINPLL-DSGLATSI------SQGPAGANALNERLARAQSRN----VLDANDRYVTEC 115
           G     ++ D GL+T+I      + G + +    E++ R ++ N      D+ +R + + 
Sbjct:  88 GAPTTKMMHDKGLSTNIGWQNKDAYGKSLSPRQREQMQRLRTWNERFRTRDSKERNLKQA 147

Query: 116 YNRISYLCERSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFI 175
              I  +    GLP+ V++ A  + R       L  D +  R+         + ++AL+ 
Sbjct: 148 LGEIDRMASALGLPENVRETASVIYR-----RALNDDLLPGRS------IEGVATSALYA 196

Query: 176 ACRNEGFPRTFNEISVIVSVAK---SRVAAY-VKAMEMSIGEAAKISRIRTTDDFVSRFC 231
           + R  G PR+ +E+  +  V K   +R   Y V+ +++ I  A         + +V RF 
Sbjct: 197 SARMAGTPRSLDELEKVSRVDKMELTRTYRYIVRELKLEIKPA-------DPEQYVPRFA 249

Query: 232 SYLEIPNIVRSLVNQVARAAAEKDGIH-GRTLVSIAAGAIYFVLLLWRETCPQSIPATLR 290
           S L + +       Q+ R A E  GIH G++ V +AA A+Y   LL  E   QS  +T+ 
Sbjct: 250 SELGLSDEAERQARQLLRDAKET-GIHSGKSPVGLAAAAVYAAALLTNEKVTQSEVSTVA 308

Query: 291 -VSDEALVNRIAEVSGITEGVV 311
            +S+  + NR  E+  + +G +
Sbjct: 309 DISEVTIRNRYKELLEVQDGTL 330

ref|NP_279414.1| TfbF [Halobacterium sp. NRC-1]
gb|AAG18894.1| transcription initiation factor IIB; TfbF [Halobacterium sp. NRC-1]
pir||B84191 transcription initiation factor IIB [imported] - Halobacterium sp. NRC-1
sp|Q9HSB3|TF2B6_HALN1 Transcription initiation factor IIB 6 (TFIIB 6)
(319 aa)

Score: 72 bits (177), Expect: 1.60305e-11
Length: 264, Idn/Pos/Gap = 72/122/30 (27%/46%/11%)

Query:   7 ERDVPDVCGECGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRV  66
           E +  D C ECG   +V D ++G+ VCA CG+V  E  ID G EWR F++ +   + +RV
Sbjct:  18 ESESTDGCPECGGL-VVNDEEHGESVCADCGLVVEEDGIDRGPEWRAFDSKEKD-EKSRV  75

Query:  67 GG-SINPLLDSGLATSIS--QGPAGANALN-------ERLARAQSR-NVLDANDRYVTEC 115
           G  + N + D GL+T+I      A  N+L+       +RL +   R    DA +R + + 
Sbjct:  76 GAPTTNTMHDKGLSTNIDWRDKDAYGNSLSSNQRQKMQRLRKWNERFRTRDAKERNLKQA 135

Query: 116 YNRISYLCERSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFI 175
              I  +    GLP  V++ A  + R   +   L    +   A           ++ ++ 
Sbjct: 136 LGEIDRMASALGLPDNVRETASVIYRRALEDDLLPGRSIEGVA-----------TSCVYA 184

Query: 176 ACRNEGFPRTFNEISVIVSVAKSRVAAYVKAMEMSIG-EAAKISRIRTTDDFVSRFCSYL 234
           A R  G PR+ +EI+ +  V K+ +A   + +   +G E A        + +V RF S L
Sbjct: 185 AARQAGVPRSLDEIADVSRVEKAEIARTYRYVVRELGLEVAPAD----PESYVPRFASDL 240

Query: 235 EIPNIVRSLVNQVARAAAEKDGIH 258
            + +       ++ + A +K G+H
Sbjct: 241 GLSDEASHRARELLKTAKDK-GVH 263

ref|NP_279833.1| TfbD [Halobacterium sp. NRC-1]
gb|AAG19313.1| transcription initiation factor IIB; TfbD [Halobacterium sp. NRC-1]
pir||E84243 transcription initiation factor IIB [imported] - Halobacterium sp. NRC-1
sp|Q9HR45|TF2B4_HALN1 Transcription initiation factor IIB 4 (TFIIB 4)
(328 aa)

Score: 72 bits (175), Expect: 2.94763e-11
Length: 238, Idn/Pos/Gap = 69/107/35 (28%/44%/14%)

Query:  14 CGECGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGG-SINP  72
           C EC   DLV D   G+  C +CG+V  E  ID G EWR F N     + +RVG  + N 
Sbjct:  32 CPECNG-DLVTDEDRGETTCGECGLVVEEDGIDHGPEWRAF-NAQEQDEKSRVGAPTTNM  89

Query:  73 LLDSGLATSI--SQGPAGANALNERLARAQSR--------NVLDANDRYVTECYNRISYL 122
           + D GL+T+I      A  N L+ R  R   R           ++ +R + +    I  +
Sbjct:  90 MHDKGLSTNIGWQDKDAYGNTLSGRQRRKMQRLRKWNERFRTRNSKERNLKQALGEIERM 149

Query: 123 CERSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGF 182
               GLP  V++ A  + R       LG D +  R+         + ++AL+ A R    
Sbjct: 150 ASAFGLPDSVRETASVIYR-----RALGEDLLPGRS------IEGVATSALYAAARQANT 198

Query: 183 PRTFNEISVIVSVAKSRVAAYVK--AMEMSIGEAAKISRIRTTD--DFVSRFCSYLEI 236
           PR+ +E++ +  V +  +A   +  A E+S+        +  TD   +V RFCS LE+
Sbjct: 199 PRSLDEVASVSRVDRGEIARTYRYVARELSL-------EVAPTDPASYVPRFCSDLEL 249

ref|NP_247767.1| transcription initiation factor IIB (TFIIB) [Methanocaldococcus jannaschii DSM 2661]
gb|AAB98771.1| transcription initiation factor IIB (TFIIB) [Methanocaldococcus jannaschii DSM 2661]
pir||F64397 transcription initiation factor IIB homolog  (intein-containing) - Methanococcus jannaschii
sp|Q58192|TF2B_METJA Transcription initiation factor IIB homolog (TFIIB) [Contains: Endonuclease Mja Tfb (Mja Tfb intein) (Mja TFIIB intein)]
(673 aa)

Score: 69 bits (169), Expect: 1.22777e-10
Length: 269, Idn/Pos/Gap = 74/116/50 (27%/43%/18%)

Query:  71 NPLLDSGLATSI------SQG---PAGANALNERLARAQSR-NVLDANDRYVTECYNRIS 120
           N + D GL+T I      S G    A   A   RL + Q R  V DA +R +    + + 
Sbjct: 434 NTIHDKGLSTVIDWRNKDSYGKDLSANKRAQLYRLRKWQRRIRVSDAAERNLAFALSELD 493

Query: 121 YLCERSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNE 180
            +  + GLP+ V++ A  + R           G   +   R      +++AA++ ACR  
Sbjct: 494 RITSKLGLPRHVRENAAIIYR-----------GAVEKGLIRGRSIEGVVAAAIYAACRRC 542

Query: 181 GFPRTFNEISVIVSVAKSRVAAYVK--AMEMSIGEAAKISRIRTTD--DFVSRFCSYLEI 236
             PRT +EI+    V +  +    +  A E++I       ++  T+  D+V RF S L +
Sbjct: 543 RVPRTLDEIAEASRVDRKEIGRTYRFLARELNI-------KLTPTNPIDYVPRFASELGL 595

Query: 237 PNIVRSLVNQVARAAAEKDGIHGRTLVSIAAGAIYF--VLLLWRETCPQSIPATLRVSDE 294
           P  V S   Q+ + AAEK    GR    +AA AIY   VLL  R T              
Sbjct: 596 PGEVESKAIQILQQAAEKGLTSGRGPTGVAAAAIYIASVLLGCRRT-------------- 641

Query: 295 ALVNRIAEVSGITEGVVKTVASRIRQYRD 323
                +AEV+G+TE  ++     + ++ D
Sbjct: 642 --QREVAEVAGVTEVTIRNRYKELTEHLD 668


Score: 53 bits (127), Expect: 1.09399e-05
Length: 50, Idn/Pos/Gap = 22/34/0 (44%/68%/0%)

Query:  8 RDVPDVCGECGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFEND 57
          R+   VC  CGS ++V+D +  ++VCA+CG V  E L D+G EWR F+++
Sbjct: 36 REEEIVCPICGSKEVVKDYERAEIVCAKCGCVIKEKLFDIGPEWRAFDHE 85

ref|NP_578416.1| hypothetical transcription initiation factor IIB chain b [Pyrococcus furiosus DSM 3638]
gb|AAL80811.1| transcription initiation factor IIB chain b homolog; (TFIIB) [Pyrococcus furiosus DSM 3638]
(283 aa)

Score: 68 bits (166), Expect: 3.31382e-10
Length: 294, Idn/Pos/Gap = 71/116/36 (24%/39%/12%)

Query:  11 PDVCGECGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSI  70
           P  C  C S DLV D ++G++ C +CG + A  L+D     +T  ND   Y   R+G   
Sbjct:  14 PVKCPYCKSRDLVYDRQHGEVFCKKCGSILATNLVDSELSRKTKTNDIPRYT-KRIG---  69

Query:  71 NPLLDSGLATSISQGPAGANALNERLARAQSRNVLDANDRYVTECYNRISYLCERSGLPQ 130
                                  E++ R +      +++R +    + +  L     LP+
Sbjct:  70 -------------------EFTREKIYRLRKWQKKISSERNLVLAMSELRRLSGMLKLPK 110

Query: 131 LVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRTFNEIS 190
            V++ A  L R               R   R     + ++A ++  CR    PRT NEI+
Sbjct: 111 YVEEEAAYLYR-----------EAAKRGLTRRIPIETTVAACIYATCRLFKVPRTLNEIA 159

Query: 191 VIVSVAKSRVAAYVKAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPNIVRSLVNQVARA 250
                 K  +    + +  ++    K+   R T D+V +F   LE+   VR     + R 
Sbjct: 160 SYSKTEKKEIMKAFRVIVRNLNLTPKMLLARPT-DYVDKFADELELSERVRRRTVDILRR 218

Query: 251 AAEKDGIHGRTLVSIAAGAIYFVLLLWRETCPQ-SIPATLRVSDEALVNRIAEV 303
           A E+    G+  +S+ A A+Y   LL  E   Q  I     VS+  + NR  E+
Sbjct: 219 ANEEGITSGKNPLSLVAAALYIASLLEGERRSQKEIARVTGVSEMTVRNRYKEL 272

ref|NP_280839.1| TfbA [Halobacterium sp. NRC-1]
gb|AAG20319.1| transcription initiation factor IIB; TfbA [Halobacterium sp. NRC-1]
pir||C84369 transcription initiation factor IIB [imported] - Halobacterium sp. NRC-1
sp|Q9HNA2|TF2B1_HALN1 Transcription initiation factor IIB 1 (TFIIB 1)
(287 aa)

Score: 67 bits (164), Expect: 4.86426e-10
Length: 302, Idn/Pos/Gap = 78/119/33 (25%/39%/10%)

Query:  11 PDVCGECGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSI  70
           P  C EC  T    DT++   VCA CG+V  +  ID G EWRTF +DD  + P R G  +
Sbjct:   4 PHRCPECDGTIRETDTEH---VCADCGLVVTDAPIDHGPEWRTF-SDDPDHAPERTGAPL  59

Query:  71 N-PLLDSGLATSISQGPAGANALNERLARAQSRN----VLDANDRYVTECYNRISYLCER 125
                D GL+T I            + AR + ++    +    D      +  I  L   
Sbjct:  60 TRSRHDRGLSTEIGYSARLTGRKRRKFARLRRQHKRATIPSKADYNRIYGFTEIRRLIGT 119

Query: 126 SGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRT 185
            G+   ++D+AC    L+    T G    R    F         +A ++  CR  G  RT
Sbjct: 120 FGIGTGLRDQACT---LFASAQTAGLLHGRTIEGF--------AAAGVYATCRTNGVTRT 168

Query: 186 FNEISVIVSVAKSRVAAYVKAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPNIVRSLVN 245
            +EI+      +  +     AM   +G        R   +++ R+   L +P  +     
Sbjct: 169 LDEIAAAARATRPELTTAYDAMNRDLGLPTGPIDPR---EYLPRYADALSLPARIERQAR 225

Query: 246 QVARAAAEKDG-IHGRTLVSIAAGAIYFVLLLWRETCPQS--------IPATLRVSDEAL 296
           ++  AA E DG + GR    +AAG +Y           QS         P TLR + + L
Sbjct: 226 ELV-AALETDGLVAGRNPSGVAAGCLYTAATETDHAVTQSAAAAVADVTPVTLRATYQNL 284

Query: 297 VN 298
            +
Sbjct: 285 TD 286

gb|AAV46081.1| transcription initiation factor IIB [Haloarcula marismortui ATCC 43049]
ref|YP_135787.1| transcription initiation factor IIB [Haloarcula marismortui ATCC 43049]
(322 aa)

Score: 65 bits (159), Expect: 1.74355e-09
Length: 315, Idn/Pos/Gap = 84/149/36 (26%/47%/11%)

Query:   5 TMERDVPDVCGECGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPN  64
           + E++  + C EC S ++V DT++G+ VC  CG+V  E  ID G EWR F N       +
Sbjct:  20 STEQEAVETCPEC-SGNVVTDTEHGETVCEDCGLVVEEDEIDRGPEWRAF-NSAEKDRKS  77

Query:  65 RVGG-SINPLLDSGLATSI------SQGPAGANALNERLARAQSRN----VLDANDRYVT 113
           RVG  + N + D GL+T+I      + G + ++   +++ R ++ N      D+ +R + 
Sbjct:  78 RVGAPTTNMMHDKGLSTNIGWQNKDAYGRSLSSEQRQKMQRLRTWNERFRTRDSKERNLK 137

Query: 114 ECYNRISYLCERSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAAL 173
           +    I  +    GLPQ V++ +  + R       LG D +  R+         + +AAL
Sbjct: 138 QALGEIDRMASALGLPQNVRETSSVIYR-----RALGDDLLPGRS------IEGVATAAL 186

Query: 174 FIACRNEGFPRTFNEISVIVSVAK---SRVAAY-VKAMEMSIGEAAKISRIRTTDDFVSR 229
           + A R  G PR+ +E++ +  V K   +R   Y V+ + + +  A         + ++ R
Sbjct: 187 YAAARMAGNPRSLDEMARVSRVEKMELTRTYRYIVRELSLEVQPA-------DPEHYLPR 239

Query: 230 FCSYLEIPNIVRSLVNQVARAAAEKDGIHGRTLVSIAAGAIYFVLLLWRETCPQS-IPAT 288
           F S L++    +     +   A +   + G++ V IAA A+Y   LL  E   QS +   
Sbjct: 240 FISDLDLSEETQRQARDLVEGARQSGMLSGKSPVGIAAAAVYAAALLTNEKVTQSQVSDV 299

Query: 289 LRVSDEALVNRIAEV 303
             +S+  + NR  E+
Sbjct: 300 ADISEVTIRNRYKEL 314

ref|NP_342431.1| Transcription initiation factor IIB (TFIIB) homolog (TFB-2) [Sulfolobus solfataricus P2]
gb|AAK41221.1| Transcription initiation factor IIB (TFIIB) homolog (TFB-2) [Sulfolobus solfataricus P2]
sp|P58110|TF2B2_SULSO Transcription initiation factor IIB 2 (TFIIB 2)
pir||F90245 hypothetical protein TFB-2 [imported] - Sulfolobus solfataricus
(293 aa)

Score: 63 bits (154), Expect: 6.51584e-09
Length: 293, Idn/Pos/Gap = 57/126/15 (19%/43%/5%)

Query:  14 CGECGSTDLVE-DTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSINP  72
           C  C + + +  D + G  VC  C  V  +  +D G +WR +   D   +  RVG    P
Sbjct:   3 CPYCKTDNAITYDVEKGMYVCTNCASVIEDSAVDPGPDWRAYNAKDRN-EKERVGSPSTP  61

Query:  73 LL-DSGLATSISQGPAGANALNERLARAQSRNVLDANDRYVTECYNRISYLCERSGLPQL 131
            + D G  T I  G A       ++ R Q++  +   D+ +    + ++    +  LP+ 
Sbjct:  62 KVHDWGFHTIIGYGRAKDRLKTLKMQRMQNKIRVSPKDKKLVTLLSILNDESSKLELPEH 121

Query: 132 VKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRTFNEISV 191
           VK+ A  ++R       +   G+  R      +  ++I AAL+ +C+    PR   E  V
Sbjct: 122 VKETASLIIR------KMVETGLTKRI-----DQYTLIVAALYYSCQVNNIPRHLQEFKV 170

Query: 192 IVSVAKSRVAAYVKAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPNIVRSLVNQVARAA 251
             S++ S   + +K ++                +++ +    L +P I+ +  +++    
Sbjct: 171 RYSISSSEFWSALKRVQYVANSIPGFRPKIKPAEYIPKILYKLNLPPIIGTKASELVDLM 230

Query: 252 AEKDGIHGRTLVSIAAGAIYFV-LLLWRETCPQSIPATLRVSDEALVNRIAEV 303
            ++    G+  +S++A ++Y +  L+  +   + +  +L +++  + NR  ++
Sbjct: 231 HKQGLTSGKGYLSLSAASVYLISALMDIKKTQKEVADSLDITEVTIRNRYKDI 283

emb|CAA50006.1| transcription factor IIB [Pyrococcus woesei]
(261 aa)

Score: 62 bits (151), Expect: 1.48837e-08
Length: 263, Idn/Pos/Gap = 68/119/19 (25%/45%/7%)

Query:  47 LGHEWRTFENDDSAYDPNRVGGSINPLL-DSGLATSISQGPAGANALNE---RLARAQSR 102
           +G EWR F+        +R G   + LL D GL+T I    + +  + E   RL + QSR
Sbjct:   1 MGPEWRAFDASQRERR-SRTGAPESILLHDKGLSTEIGIDRSLSGLMREKMYRLRKWQSR  59

Query: 103 -NVLDANDRYVTECYNRISYLCERSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFR 161
             V DA +R +    + +  +  +  LP+ V++ A  L R          + VR +   R
Sbjct:  60 LRVSDAAERNLAFALSELDRITAQLKLPRHVEEEAARLYR----------EAVR-KGLIR 108

Query: 162 EDETASIISAALFIACRNEGFPRTFNEISVIVSVAKSRVAAYVKAMEMSIGEAAKISRIR 221
                S+++A ++ ACR    PRT +EI+ I  V K  +    + +  ++    K   ++
Sbjct: 109 GRSIESVMAACVYAACRLLKVPRTLDEIADIARVDKKEIGRSYRFIARNLNLTPKKLFVK 168

Query: 222 TTDDFVSRFCSYLEIPNIVRSLVNQVARAAAEKDGIHGRTLVSIAAGAIYFVLLLWRETC 281
            T D+V++F   L +   VR    ++   A ++    G++   + A A+Y   LL  E  
Sbjct: 169 PT-DYVNKFADELGLSEKVRRRAIEILDEAYKRGLTSGKSPAGLVAAALYIASLLEGEKR 227

Query: 282 PQ-SIPATLRVSDEALVNRIAEV 303
            Q  +    RV++  + NR  E+
Sbjct: 228 TQREVAEVARVTEVTVRNRYKEL 250

gb|AAU82778.1| transcription initiation factor IIB [uncultured archaeon GZfos1C11]
(227 aa)

Score: 61 bits (148), Expect: 3.48597e-08
Length: 129, Idn/Pos/Gap = 42/67/10 (32%/51%/7%)

Query:  14 CGECGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSIN-P  72
           C ECGS +++ D+++ +L CA CGVV AE ++DLG EWR+++ ++ A    R G  ++  
Sbjct:  11 CPECGSKNVITDSRHAELYCADCGVVIAENIVDLGPEWRSYD-EEQASKRIRTGPPMSYR  69

Query:  73 LLDSGLATSISQGPAGANALNERLARAQSRNVLDANDRYVTECYNRISYLCERSGLPQLV 132
           + D GL T     PA       R  R  S   +D++D+ +      I  +    GLP  +
Sbjct:  70 IHDKGLGTPTPGLPA-----RTRRLRGIS---IDSSDKTLAFALVEIDRMACALGLPNNI 121

Query: 133 KDRACELLR 141
           K+    L R
Sbjct: 122 KEATSVLYR 130

ref|NP_395867.1| TfbE [Halobacterium sp. NRC-1]
gb|AAG21002.1| transcription initiation factor IIB; TfbE [Halobacterium sp. NRC-1]
sp|Q9HHH8|TF2B5_HALN1 Transcription initiation factor IIB 5 (TFIIB 5)
(307 aa)

Score: 61 bits (148), Expect: 3.88535e-08
Length: 276, Idn/Pos/Gap = 71/110/31 (25%/39%/11%)

Query:   6 MERDVPDVCGECGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNR  65
           ++R   + C ECG       T + + VCA CG++  E  ID G EW    + D A    R
Sbjct:  15 IQRGTTEPCPECGGP---VRTNSAETVCADCGLIIDEQSIDRGPEW----HRDDADTAKR  67

Query:  66 VGGSINPLL-DSGLATSISQGP-AGANALNER-------LARAQSRNVL-DANDRYVTEC 115
            G  + P   D GL+T I  G  A   AL+         + R QSR       +R +   
Sbjct:  68 TGAPLTPARHDRGLSTVIGSGQDARGTALSSEKRRRLARMRREQSRGRWRSTKERNLGHG 127

Query: 116 YNRISYLCERSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFI 175
              I  +    GL   V+D+AC+L R   +   L    + A A           +A++F 
Sbjct: 128 LTEIRRIASALGLADSVRDQACQLFRTAQNERLLKGRSIEAMA-----------AASVFG 176

Query: 176 ACRNEGFPRTFNEISVIVSVAKSRVAAYVKAMEMSIGEAAKISRIRTTDDFVSRFCSYLE 235
           ACR  G     ++++ +  V ++RV      +   +G       +   D FV R  S L 
Sbjct: 177 ACRCNGESWLIDDVAPMAQVGQNRVENAYTVLNEELGLPTPPVSL---DQFVPRLASDLG 233

Query: 236 IPNIVRSLVNQVARAAAEKDGIHGRTLVSIAAGAIY 271
             ++VR    ++   A +     G      AA  +Y
Sbjct: 234 CTDVVRRRAEELVVQAVDAGITTGVHPSGFAAACLY 269

ref|YP_134329.1| transcription initiation factor IIB [Haloarcula marismortui ATCC 43049]
gb|AAV44623.1| transcription initiation factor IIB [Haloarcula marismortui ATCC 43049]
(320 aa)

Score: 61 bits (147), Expect: 4.44027e-08
Length: 212, Idn/Pos/Gap = 53/95/24 (25%/44%/11%)

Query:  12 DVCGECGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSIN  71
           ++C EC    +   + +G+  C  CG+V  +  ID G EWR F +++   + +RVG    
Sbjct:  25 NICPEC-QGHITRTSDSGEATCESCGLVFEDNPIDHGPEWRAFTSEERD-EKSRVGAPTT  82

Query:  72 PLL-DSGLATSI------SQGPAGANALNERLARAQSRN----VLDANDRYVTECYNRIS 120
            L+ D GL+T+I      + G A +     +L R ++ +      DA++R + +    IS
Sbjct:  83 QLMHDKGLSTTIGWQDKDAYGQAVSGRKRAQLQRLRTWDERFRTKDAHERNLKQALGEIS 142

Query: 121 YLCERSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNE 180
            +    GLP+ V++ A  L R   +   L    +   +           +A+L+ A R  
Sbjct: 143 RMASALGLPESVRETAGVLYRRAVEQNLLPGRSIEGMS-----------TASLYAAARQH 191

Query: 181 GFPRTFNEISVIVSVAKSRVAAYVKAMEMSIG 212
           G PR   E + +  V K R+    + +   +G
Sbjct: 192 GMPRPLTEFADVSRVEKIRIQRAYRYLSRELG 223

gb|AAF18139.1| archaeal transcription factor B [Sulfolobus acidocaldarius]
sp|Q9UWN6|TF2B_SULAC Transcription initiation factor IIB (TFIIB)
(309 aa)

Score: 60 bits (144), Expect: 1.11176e-07
Length: 234, Idn/Pos/Gap = 56/102/26 (23%/43%/11%)

Query:  17 CGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSINPLL-D  75
           C    ++ D + G+ +C + G V  E +ID G EWR F  ++     +RVGG +N  + D
Sbjct:  13 CPPDKIIFDEERGEYICTETGEVIEERIIDQGPEWRAFTPEEKE-KRSRVGGPLNQTIHD  71

Query:  76 SGLATSI--SQGPAGANALNE-------RLARAQSRNVLDAN-DRYVTECYNRISYLCER 125
            G++T I      A   +L+        R  + Q R  + ++ DR + +  N +  +   
Sbjct:  72 MGISTVIDWKDKDAMGRSLDPKRRLEVLRWRKWQIRTRIQSSIDRNLAQAMNELERIGNL 131

Query: 126 SGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRT 185
             LP+ VKD A  + R   +           +   R     S+++A+++ ACR     RT
Sbjct: 132 LNLPKAVKDEAALIYRKAVE-----------KGLVRGRSIESVVAASIYAACRRMKMART 180

Query: 186 FNEISVIVSVAKSRVAAYVKAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPNI 239
            +EI+      +  VA   + +   +     +S  +   D+V+R  + L +  I
Sbjct: 181 LDEIAQFTKANRKEVARCYRLILRELDIEVPVSDPK---DYVTRIGTLLSLSGI 231

gb|AAB32638.1| transcription factor IIB, TFIIB=sua7-1 variant [Saccharomyces cerevisiae, Peptide Partial Mutant, 68 aa]
(68 aa)

Score: 59 bits (143), Expect: 1.46417e-07
Length: 64, Idn/Pos/Gap = 31/41/3 (48%/64%/4%)

Query: 14 CGECG--STDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDD-SAYDPNRVGGSI 70
          C EC      +VE    GD+VCA CG+V ++ L+D   +WRTF NDD +  DP+RVG + 
Sbjct:  5 CPECKVYPPKIVERFSEGDVVCALCGLVLSDKLVDTRSKWRTFSNDDHNGDDPSRVGEAS 64

Query: 71 NPLL 74
          NPLL
Sbjct: 65 NPLL 68

gb|AAR28006.1| TFIIB6 [Arabidopsis thaliana]
emb|CAB81169.1| putative protein [Arabidopsis thaliana]
emb|CAB40034.1| putative protein [Arabidopsis thaliana]
gb|AAC35529.1| contains similarity to transcription factor TFIIB repeat domains (Pfam: transcript_fac2.hmm, score: 49.16) [Arabidopsis thaliana]
ref|NP_192806.1| transcription factor IIB (TFIIB) family protein [Arabidopsis thaliana]
pir||T01909 transcription initiation factor IIB homolog T12H20.13 - Arabidopsis thaliana
(182 aa)

Score: 59 bits (142), Expect: 1.78878e-07
Length: 203, Idn/Pos/Gap = 55/87/31 (27%/42%/15%)

Query:  13 VCGECGS-TDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSIN  71
           +C EC   T+ V + KNGD +C +CG V    +ID                 +  G S N
Sbjct:   6 ICLECKRPTETVVNYKNGDTICIECGHVIENNIID-----------------DLDGASTN  48

Query:  72 PLLDSG-LATSISQGPAGANALNERLARAQSRNVLDANDRYVTE-CYNRISYLCERSGLP 129
           P L SG L T I +    +++L  +L R Q+  + +  +  V +  Y  I  + E  GL 
Sbjct:  49 PNLKSGHLPTIIFKLSGKSSSLASKLRRTQNEMIKNKQEEDVIKIAYAEIERMTEALGLT 108

Query: 130 QLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRTFNEI 189
             + + AC++L        L    +R     R      + +A++  ACR    P+T  EI
Sbjct: 109 FGISNTACKILS------KLDKKNLRGGKSLR-----GLCAASVSRACRQVNIPKTLKEI 157

Query: 190 SVIVSVAKSRVAAYVKAMEMSIG 212
           S + +V    +   VK +  S G
Sbjct: 158 SAVANVDMKEINKAVKLLGDSFG 180

gb|AAB32639.1| transcription factor IIB, TFIIB=sua7-3 variant [Saccharomyces cerevisiae, Peptide Partial Mutant, 68 aa]
(68 aa)

Score: 58 bits (139), Expect: 4.55413e-07
Length: 64, Idn/Pos/Gap = 31/40/3 (48%/62%/4%)

Query: 14 CGECG--STDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDD-SAYDPNRVGGSI 70
          C EC      +VE    GD+VCA CG+V ++ L+D   EWRTF NDD +  DP+ VG + 
Sbjct:  5 CPECKVYPPKIVERFSEGDVVCALCGLVLSDKLVDTRSEWRTFSNDDHNGDDPSCVGEAS 64

Query: 71 NPLL 74
          NPLL
Sbjct: 65 NPLL 68

gb|AAV46908.1| transcription initiation factor IIB [Haloarcula marismortui ATCC 43049]
ref|YP_136614.1| transcription initiation factor IIB [Haloarcula marismortui ATCC 43049]
(339 aa)

Score: 57 bits (138), Expect: 5.38119e-07
Length: 265, Idn/Pos/Gap = 63/112/35 (23%/42%/13%)

Query:  14 CGECGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSINPL  73
           C +CG + LV D   G+ VC  CG+V  E  ID G EWR F++ +   +  RVG     +
Sbjct:  30 CPDCGGS-LVTDDSRGETVCESCGLVVDEDEIDHGPEWRAFDSQERD-NKRRVGAPTTEM  87

Query:  74 L-DSGLATSI--SQGPAGANALNERLARAQSR--------NVLDANDRYVTECYNRISYL 122
             D GL+T+I      A  N+L+ R      R           D  +R + +    I  +
Sbjct:  88 KHDKGLSTNIGWQDKDAYGNSLSTRQREKMQRLRTWDERFRTRDHAERNLKQALGEIDRM 147

Query: 123 CERSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGF 182
               G+P+  ++ A  + R   D   L    +   A           +AAL+ A R    
Sbjct: 148 GSALGVPESARETASVIYRRALDEGMLPGRSIEGMA-----------TAALYAAVRQANL 196

Query: 183 PRTFNEISVIVSVAK---SRVAAYV-KAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPN 238
           P+T ++++V+  V +   +R   Y+ + + + +G     +       ++S+F S L+  +
Sbjct: 197 PQTLDDMAVVSRVDEMEFTRAYRYLNRELSLQVGPPDPAT-------YLSKFVSKLDADD 249

Query: 239 IVRSLVNQVARAAAEKDGIHGRTLV 263
            +      +  A  E +   G++ V
Sbjct: 250 ALERQARALIEAGKEANVHSGKSPV 274

ref|NP_376220.1| hypothetical transcription initiation factor IIB [Sulfolobus tokodaii str. 7]
dbj|BAB65329.1| 308aa long hypothetical transcription initiation factor IIB [Sulfolobus tokodaii str. 7]
sp|Q975S1|TF2B_SULTO Transcription initiation factor IIB (TFIIB)
(308 aa)

Score: 57 bits (138), Expect: 5.65745e-07
Length: 256, Idn/Pos/Gap = 59/104/28 (23%/40%/10%)

Query:  17 CGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSINPLL-D  75
           C    +V D + G+ +C + G V  E  ID G EWR F  ++     +RVGG +N  + D
Sbjct:  14 CPPDKIVFDEERGEYICTETGEVIEERAIDQGPEWRAFTPEEKE-KRSRVGGPLNQTIHD  72

Query:  76 SGLATSISQGPAGA-----------NALNERLARAQSRNVLDANDRYVTECYNRISYLCE 124
            G++T I      A             L  R  + ++R +  + DR + +  N +  +  
Sbjct:  73 MGISTVIDWKDKDAMGRTLDPKRRLEVLRWRKWQIRAR-IQSSIDRNLAQAMNELERIGN 131

Query: 125 RSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPR 184
              LP+ VKD A  + R   +           +   R     S+++A+++ ACR     R
Sbjct: 132 LLNLPKAVKDEAALIYRKAVE-----------KGLVRGRSIESVVAASIYAACRRMKMAR 180

Query: 185 TFNEISVIVSVAKSRVAAYVKAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPNIVRSLV 244
           T +EI+      +  VA   + +   +     +S  +   D+V+R  S L +      + 
Sbjct: 181 TLDEIAQFTKANRKEVARCYRLILRELDINVPVSDPK---DYVTRIGSLLGLSGSTMKMA 237

Query: 245 NQVARAAAEKDGIHGR 260
             +   A E     G+
Sbjct: 238 IDIIEKAKESGLTAGK 253

emb|CAC82716.1| TFIIB-related protein [Zea mays]
(469 aa)

Score: 57 bits (137), Expect: 6.20127e-07
Length: 217, Idn/Pos/Gap = 54/94/25 (24%/43%/11%)

Query: 160 FREDETASIISAALFIACRNEGFPRTFNEISVIVSVAKSRVAAYVKAMEMSIGEAAKISR 219
            R     ++ +AAL  A R    PRT  EIS   ++ +  +  Y+K +    GE+ K+S+
Sbjct: 120 LRNRSVEALATAALVQAIREAQQPRTLQEISTASNLPQKEIGKYIKIL----GESLKLSQ 175

Query: 220 IRTTDDF---VSRFCSYLEIPNIVRSLVNQVARAAAEKDGIHGRTLVSIAAGAIYFVLLL 276
              ++     + RFCS L++    + L   +    A K     R  +SI+A AIY    L
Sbjct: 176 PLNSNSIAVHMPRFCSLLQLNKSAQELAAHIGEVVANKCFCTRRNPISISAAAIYLACQL 235

Query: 277 WRETCPQSIPATLRVSDEALVNRIAEVSGITEGVVKTVASRIRQYRDRGLLPPDWVRRFP 336
             +   Q+               I +V+G+TE  ++ V   + +  D  LLPPD+    P
Sbjct: 236 EDKRKTQA--------------EICKVTGLTEVTLRKVYKELLENWD-DLLPPDYTPATP 280

Query: 337 SRLEPELP-TSSSERQDPTGNELIHEQSAPTVSSKRP 372
              E   P T+    +  +G ++  ++   ++  K P
Sbjct: 281 P--EKAFPMTNIYSGRSASGKDMYQDKIFESIKQKCP 315

emb|CAH98814.1| transcription initiation factor TFIIB, putative [Plasmodium berghei]
(366 aa)

Score: 56 bits (135), Expect: 1.22919e-06
Length: 181, Idn/Pos/Gap = 43/81/20 (23%/44%/11%)

Query:  12 DVCGECGSTDLVE-DTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAY--DPNRVGG  68
           ++C +C    ++  DT  G  +C  CG+V    ++    EWR F ND  +   D NRVG 
Sbjct:  47 NICPDCKEKGIIICDTSEGTQICNGCGLVVETNILSEEQEWRNFSNDGQSKGNDRNRVGE 106

Query:  69 SINPLLDSGLATSISQGPAGANALNERLARAQSRNVLDANDRYVTECYNRISYLCERSGL 128
           + +  L++ L ++     +      ++L        ++ ND+ +   +N +  +CE   L
Sbjct: 107 TSDIWLENNLTSTTFIKSS------KKLQHLNMMTQINKNDQTLLSAFNILKLICETFFL 160

Query: 129 PQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRTFNE 188
              V +RA E+ +   D      D ++ RA          + A +++ACR  G  ++  E
Sbjct: 161 RSNVIERAKEITKELQD-----MDQLKNRANNLN------MLAVVYLACREAGHIKSIKE 209

Query: 189 I 189
           +
Sbjct: 210 L 210

emb|CAF28768.1| putative transcription initiation factor TFIIB [uncultured crenarchaeote]
(304 aa)

Score: 56 bits (134), Expect: 1.52698e-06
Length: 314, Idn/Pos/Gap = 76/133/44 (24%/42%/14%)

Query:  12 DVCGECGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSIN  71
           D C  CG   +V D  +G++ C  CG V  E + + G EWR F  ++   D +R G   +
Sbjct:  10 DRCPRCGKGPMVTDNSSGEMFCGNCGFVVTERIEETGPEWRAFSKEEHE-DRSRAGIPTS  68

Query:  72 -PLLDSGLATSISQGPAGANALN-----------ERLARAQSRN-VLDANDRYVTECYNR 118
             + D GLAT I  GP   +A             ERL    SR+ V +  DR   + ++ 
Sbjct:  69 LAMHDMGLATII--GPVDKDASGKPLSASMKSTIERLRTWDSRSQVHEPVDRNFRQAFSE 126

Query: 119 ISYLCERSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACR 178
           +  L ++  +   V ++A  + R       L    VR R+       +++++AAL+ ACR
Sbjct: 127 LDRLKDKLAVGDAVIEKAAYVYR-----KALEKGLVRGRS------ISALVAAALYAACR 175

Query: 179 NEGFPRTFNEISVIVSVAKSRVAAYVKAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPN 238
           +   PRT  +I+   ++ K  VA   +   + I E      +      V+R  S   +  
Sbjct: 176 DTETPRTLKDIAHASNIKKKDVA---RCYRLLIRELDLKMPVVDPVKCVARIASKSGLSE 232

Query: 239 IVRSLVNQVARAAAEKDGIHGRTLVSIAAGAIYFVLLLWRETCPQSIPATLRVSDEALVN 298
             +    ++ + A +     G+  + +AA A+Y   ++  E   Q               
Sbjct: 233 KTKRKALEILKKAEQGKISAGKDPMGLAAAALYVACVMNGENKTQ--------------K 278

Query: 299 RIAEVSGITEGVVK 312
            +AE +G+TE  ++
Sbjct: 279 DVAEAAGVTEVTIR 292

emb|CAC82715.1| TFIIB-related protein [Spinacia oleracea]
(414 aa)

Score: 55 bits (133), Expect: 1.91281e-06
Length: 220, Idn/Pos/Gap = 53/92/40 (24%/41%/18%)

Query: 160 FREDETASIISAALFIACRNEGFPRTFNEISVIVSVAKSRVAAYVKAMEMSIGEAAKISR 219
            R     ++ +A L  A R    PRT  EIS+  ++ +  +  Y+K +    GEA ++S+
Sbjct: 160 LRNRSVEALATACLVQAIREAQEPRTLQEISIAANLPQKEIGKYIKIL----GEALQLSQ 215

Query: 220 IRTTDDF---VSRFCSYLEIPNIVRSLVNQVARAAAEKDGIHGRTLVSIAAGAIYFVLLL 276
              ++     + RFC+ L++    + L   +      K     R  +SI+A AIY    L
Sbjct: 216 PINSNSIAVHMPRFCNLLQLNKSAQELATHIGEVVMNKCFCTRRNPISISAAAIYLACQL 275

Query: 277 WRETCPQSIPATLRVSDEALVNRIAEVSGITEGVVKTVASRIRQYRDRGLLPPDWV---- 332
                 Q+               I +V+G+TE  ++ V   + +  D  LLP ++     
Sbjct: 276 EDRRKTQA--------------EICKVTGLTEVTLRKVYKELLENWD-DLLPSNYTPVVP 320

Query: 333 --RRFPS-----------RLE-PELPTSSSERQDPTGNEL 358
             + FP+           R E PE+PT   E + P  N++
Sbjct: 321 PEKAFPTTTIASGRSVTPRAEPPEIPTLDRESKQPKTNQI 360

ref|YP_134372.1| transcription initiation factor IIB 5 [Haloarcula marismortui ATCC 43049]
gb|AAV44666.1| transcription initiation factor IIB 5 [Haloarcula marismortui ATCC 43049]
(310 aa)

Score: 55 bits (132), Expect: 2.69304e-06
Length: 267, Idn/Pos/Gap = 61/105/28 (22%/39%/10%)

Query:  16 ECGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSINPLL-  74
           +C   D    T   + +C  CG+V  E  ID G EWR ++ D+      R G  +     
Sbjct:  27 QCPECDGRVTTNAVETICEDCGLVIEEQRIDHGPEWRAYDADER----ERTGAPLTTARH  82

Query:  75 DSGLATSISQGP-AGANALN-------ERLARAQSRNVLDAN-DRYVTECYNRISYLCER 125
           D G++T I  G  A  N L+        R+ R Q+R    +  +R +      +  L   
Sbjct:  83 DRGISTEIGHGTDAHGNELSGQKRRQLARMRREQTRGRWRSKAERNLAHGLGEVRRLASA 142

Query: 126 SGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRT 185
             L + ++D+AC+L R             ++    R     +I +A+++  CR    P  
Sbjct: 143 LELSESIRDQACQLFR-----------SAQSEDLLRGRSIEAIGAASIYGTCRCNQHPLL 191

Query: 186 FNEISVIVSVAKSRVAAYVKAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIPNIVRSLVN 245
             ++     V  +RV    + +   +   A   R      F+ R  S LE+ + +R   N
Sbjct: 192 LEDVVDAARVESARVTNAYRTLNRELELPAPPMR---PTSFIPRLISALELDHDIRRRAN 248

Query: 246 QVARAAAEKDGIHGRTLVSIAAGAIYF 272
           ++A  A      +G     +AA  +Y 
Sbjct: 249 ELAERAEGTTLTNGCQPSGVAAACVYL 275

gb|EAL36580.1| transcription initiation factor TFIIB [Cryptosporidium hominis]
(269 aa)

Score: 55 bits (131), Expect: 3.48799e-06
Length: 131, Idn/Pos/Gap = 37/68/9 (28%/51%/6%)

Query:  14 CGECGSTD--LVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSIN  71
           C  CG+ +  +V D+K+G  +C +CGVV  + +I+   EWR+F ND +  +     GS+N
Sbjct: 142 CKRCGAGNSIVVYDSKSGSEICTRCGVVVEDRVINEEQEWRSFSNDGNDGNSKSRIGSVN 201

Query:  72 PL-LDSGLATSISQGPAGANALNERLARAQSRNVLDANDRYVTECYNRISYLCERSGLPQ 130
            + LD G   + SQ   G   L + + +    N   ++DR + E +N++  +     L  
Sbjct: 202 DVWLDDG---TDSQLLVGDKKLMKTMLK---HNTQASSDRMIKEVFNQLRQIANSFSLHD 255

Query: 131 LVKDRACELLR 141
            + +R  E+++
Sbjct: 256 NIIERCKEIVK 266

ref|NP_559444.1| transcription initiation factor IIB (TFIIB) [Pyrobaculum aerophilum str. IM2]
gb|AAL63626.1| transcription initiation factor IIB (TFIIB) [Pyrobaculum aerophilum str. IM2]
sp|Q8ZWS3|TF2B_PYRAE Transcription initiation factor IIB (TFIIB)
(333 aa)

Score: 55 bits (131), Expect: 3.76e-06
Length: 275, Idn/Pos/Gap = 68/120/29 (24%/43%/10%)

Query:  14 CGECGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSINPL  73
           C  CG+   V + + G+ VC  CG V  E L+DLG EWR F +++      R G  +  L
Sbjct:  37 CPICGNDKFVYNYERGEAVCIVCGAVVQEQLLDLGPEWRAFTSEEKGQRA-RTGAPLTRL  95

Query:  74 LDSGLATSISQGPAGANALNE---------RLARAQSR-NVLDANDRYVTECYNRISYLC 123
           +   L T I       +             RL + Q+R  V  + +R   +    +  L 
Sbjct:  96 ISEALTTVIDWRDKDVSGKELDIKRKLEVIRLRKWQTRARVQTSYERNFIQAAQELERLR 155

Query: 124 ERSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFP 183
              G+P+   ++A E+ R       L  + VR R+        ++ +AAL++ACR    P
Sbjct: 156 SAMGIPRPCIEQALEIYR-----QALEKELVRGRS------VEAMAAAALYMACRMMKMP 204

Query: 184 RTFNEISVIVSVAKSRVAAYVKAMEMSIGEAAKISRIRTTDDFVSRFCSYLEIP-NIVRS 242
           R  +E+      ++  VA   + +   +     IS       ++SR    L++   +V++
Sbjct: 205 RPLDELVRYTKASRREVARCYRLLLRELNVKVPISDPIL---YISRIAEQLKLSGEVVKT 261

Query: 243 LVNQVARAAAEKDGI-HGRTLVSIAAGAIYFVLLL 276
            ++ + +  A+K GI  G+    +AA A+Y   L+
Sbjct: 262 AIDILQK--AKKAGITAGKDPAGLAAAAVYIASLM 294

gb|AAG01118.1| BAC19.3 [Lycopersicon esculentum]
(425 aa)

Score: 52 bits (125), Expect: 1.83519e-05
Length: 211, Idn/Pos/Gap = 52/88/33 (24%/41%/15%)

Query: 160 FREDETASIISAALFIACRNEGFPRTFNEISVIVSVAKSRVAAYVKAMEMSIGEAAKISR 219
            R     ++ +AAL  A R    PRT  EISV  ++ +  +  Y+K +    GEA ++S+
Sbjct: 167 LRNRSVEALATAALVHAIREAQEPRTLQEISVAANLPQKEIGKYIKIL----GEALQLSQ 222

Query: 220 IRTTDDF---VSRFCSYLEIPNIVRSLVNQVARAAAEKDGIHGRTLVSIAAGAIYFVLLL 276
              ++     + RFC+ L++    + L   +      K     R  +SI+A AIY    L
Sbjct: 223 PINSNSISVHMPRFCTLLQLNKSAQELATHIGEVIINKCFCTRRNPISISAAAIYLACQL 282

Query: 277 WRETCPQSIPATLRVSDEALVNRIAEVSGITEGVVKTVASRIRQYRDRGLLPPDWVRRFP 336
             +   Q+               I +V+G+TE  ++ V      Y++   L  +W    P
Sbjct: 283 EDKRKTQA--------------EICKVTGLTEVTLRKV------YKE---LLENWDDLLP 319

Query: 337 SRLEPELPTSSSERQDPTGNELIHEQSAPTV 367
           S  +P +P    E+  P+        S P V
Sbjct: 320 SSYKPVVP---PEKAFPSATIATGRSSTPRV 347

pdb|1PFT| N-Terminal Domain Of Tfiib, Nmr
(50 aa)

Score: 52 bits (124), Expect: 2.22343e-05
Length: 43, Idn/Pos/Gap = 21/30/0 (48%/69%/0%)

Query: 13 VCGECGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFE 55
          VC  C S +L+ D + G++VCA+CG V  E +ID+G EWR F+
Sbjct:  7 VCPACESAELIYDPERGEIVCAKCGYVIEENIIDMGPEWRAFD 49

pdb|1RO4|A Chain A, Rdc-Derived Models Of The Zinc Ribbon Domain Of Human General Transcription Factor Tfiib (Zinc Free Structures)
pdb|1RLY|A Chain A, Rdc-Derived Models Of The Zinc Ribbon Domain Of Human General Transcription Tfiib (Zinc Bound Structures)
(60 aa)

Score: 51 bits (123), Expect: 3.23659e-05
Length: 38, Idn/Pos/Gap = 20/29/0 (52%/76%/0%)

Query: 22 LVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDS 59
          LVED + GD++C +CG+V  + +ID+G EWRTF ND +
Sbjct: 23 LVEDYRAGDMICPECGLVVGDRVIDVGSEWRTFSNDKA 60

pdb|1DL6|A Chain A, Solution Structure Of Human Tfiib N-Terminal Domain
(58 aa)

Score: 51 bits (122), Expect: 3.9873e-05
Length: 36, Idn/Pos/Gap = 20/28/0 (55%/77%/0%)

Query: 22 LVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFEND 57
          LVED + GD++C +CG+V  + +ID+G EWRTF ND
Sbjct: 22 LVEDYRAGDMICPECGLVVGDRVIDVGSEWRTFSND 57

emb|CAG59247.1| unnamed protein product [Candida glabrata CBS138]
ref|XP_446323.1| unnamed protein product [Candida glabrata]
(598 aa)

Score: 51 bits (121), Expect: 4.33427e-05
Length: 337, Idn/Pos/Gap = 89/134/62 (26%/39%/18%)

Query:  14 CGECGSTDLVED--TKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSIN  71
           C  CG+T+LV D  T N DLVC  CGVV+ E  I       TF    S      V GS  
Sbjct:   5 CKNCGNTELVVDSSTPNNDLVCVACGVVSEENPI---VSEVTFAETSSG--AATVTGS--  57

Query:  72 PLLDSGLATSISQGPAGANALNERLARAQSRNVLDANDRYVTECYNRISYLCERSGLPQL 131
             L +G   S + G  G+NA+  R A   + N      R V    N   Y+ E S     
Sbjct:  58 -FLSAG--QSHTSGGLGSNAMESREA---TLNNAKKKLRAVGHALNIPDYIVEAS----- 106

Query: 132 VKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRTFNEISV 191
                      +Y  L L  + V+ R       + ++I+A L+IACR E       + S 
Sbjct: 107 ---------HQWYK-LALAYNFVQGR------RSQNVIAACLYIACRKEMTHHMLIDFSS 150

Query: 192 IVSVAKSRVAAYVKAMEMSIGEAAKISRIRTTDD--FVSRFCSYLEIP----NIVRSLVN 245
            + V+   + A    M   +    +I+++   D   F+  F   LE+      +VR  V 
Sbjct: 151 RLQVSVYSIGATFLKMVKRL----QITKLPLADPSLFIQHFAEKLELGEKKIKVVRDAV- 205

Query: 246 QVARAAAEKDGIHGRTLVSIAAGAIYFVLLL--WRETCPQSIPATLRVSDEALVNRIAEV 303
           ++A+  +      GR    IA   I     +   R T  + I A   V++E L  R+ E 
Sbjct: 206 KLAQRMSNDWMFEGRRPAGIAGACILLACRMNNLRRTHSE-IVAVSHVAEETLQQRLNEF 264

Query: 304 SGITEGVVKTVASRIRQYR-------DRGLLPPDWVR 333
            G      K  +  ++++R       D G  PP + +
Sbjct: 265 KG-----TKAASLSVKEFRNDDPKKEDSGAAPPSFTK 296

gb|AAR28005.1| TFIIB5/pBrp [Arabidopsis thaliana]
emb|CAB16810.1| transcription initiation factor like protein [Arabidopsis thaliana]
emb|CAB80331.1| transcription initiation factor like protein [Arabidopsis thaliana]
emb|CAC82714.1| TFIIB-related protein [Arabidopsis thaliana]
gb|AAP21278.1| At4g37010 [Arabidopsis thaliana]
ref|NP_195383.1| transcription factor IIB (TFIIB) family protein [Arabidopsis thaliana]
pir||G85432 transcription initiation factor like protein [imported] - Arabidopsis thaliana
(503 aa)

Score: 51 bits (121), Expect: 4.55677e-05
Length: 188, Idn/Pos/Gap = 45/79/30 (23%/42%/15%)

Query: 160 FREDETASIISAALFIACRNEGFPRTFNEISVIVSVAKSRVAAYVKAMEMSIGEAAKISR 219
            R     ++ +A L  A R    PRT  EIS+  +V +  +  Y+K +    GEA ++S+
Sbjct: 167 LRNRSVEALATACLVQAIREAQEPRTLQEISIAANVQQKEIGKYIKIL----GEALQLSQ 222

Query: 220 IRTTDDF---VSRFCSYLEIPNIVRSLVNQVARAAAEKDGIHGRTLVSIAAGAIYFVLLL 276
              ++     + RFC+ L++    + L   +      K     R  +SI+A AIY    L
Sbjct: 223 PINSNSISVHMPRFCTLLQLNKSAQELATHIGEVVINKCFCTRRNPISISAAAIYLACQL 282

Query: 277 WRETCPQSIPATLRVSDEALVNRIAEVSGITEGVVKTVASRIRQYRDRGLLPPDWVRRFP 336
             +   Q+               I +++G+TE  ++ V      Y++   L  +W    P
Sbjct: 283 EDKRKTQA--------------EICKITGLTEVTLRKV------YKE---LLENWDDLLP 319

Query: 337 SRLEPELP 344
           S   P +P
Sbjct: 320 SNYTPAVP 327

pdb|1D3U|B Chain B, Tata-Binding ProteinTRANSCRIPTION FACTOR (II)BBRE+TATA- Box Complex From Pyrococcus Woesei
(201 aa)

Score: 50 bits (118), Expect: 0.000103223
Length: 201, Idn/Pos/Gap = 48/90/13 (23%/44%/6%)

Query: 104 VLDANDRYVTECYNRISYLCERSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFRED 163
           V DA +R +    + +  +  +  LP+ V++ A  L R          + VR +   R  
Sbjct:   2 VSDAAERNLAFALSELDRITAQLKLPRHVEEEAARLYR----------EAVR-KGLIRGR  50

Query: 164 ETASIISAALFIACRNEGFPRTFNEISVIVSVAKSRVAAYVKAMEMSIGEAAKISRIRTT 223
              S+++A ++ ACR    PRT +EI+ I  V K  +    + +  ++    K   ++ T
Sbjct:  51 SIESVMAACVYAACRLLKVPRTLDEIADIARVDKKEIGRSYRFIARNLNLTPKKLFVKPT 110

Query: 224 DDFVSRFCSYLEIPNIVRSLVNQVARAAAEKDGIHGRTLVSIAAGAIYFVLLLWRETCPQ 283
            D+V++F   L +   VR    ++   A ++    G++   + A A+Y   LL  E   Q
Sbjct: 111 -DYVNKFADELGLSEKVRRRAIEILDEAYKRGLTSGKSPAGLVAAALYIASLLEGEKRTQ 169

Query: 284 -SIPATLRVSDEALVNRIAEV 303
             +    RV++  + NR  E+
Sbjct: 170 REVAEVARVTEVTVRNRYKEL 190

ref|NP_703308.1| transcription initiation factor TFIIB, putative [Plasmodium falciparum 3D7]
emb|CAD49065.1| transcription initiation factor TFIIB, putative [Plasmodium falciparum 3D7]
(367 aa)

Score: 50 bits (118), Expect: 0.000109431
Length: 179, Idn/Pos/Gap = 40/77/20 (22%/43%/11%)

Query:  14 CGECGSTDLVE-DTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSA--YDPNRVGGSI  70
           C +C    ++  DT  G  +C  CG+V    ++    EWR F+ND  +   D NRVG   
Sbjct:  50 CPDCKEKGIIICDTSEGTQICNGCGMVVESKILSEEQEWRNFQNDGQSKNTDRNRVGEVS 109

Query:  71 NPLLDSGLATSISQGPAGANALNERLARAQSRNVLDANDRYVTECYNRISYLCERSGLPQ 130
           +  L++ L ++     +      ++L        ++ ND+ +   +N +  +C+   L  
Sbjct: 110 DIWLENNLTSTTFIKSS------KKLQHLNMMTQINKNDQTLISAFNILKLICDTFFLRS 163

Query: 131 LVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRTFNEI 189
            V +RA E+ +   D   L       + R       +++    ++ACR  G  ++  E+
Sbjct: 164 NVIERAKEITKELQDMEQL-------KNRINNLNMLAVV----YLACREAGHIKSIKEL 211

pdb|1AIS|B Chain B, Tata-Binding ProteinTRANSCRIPTION FACTOR (II)BTATA-Box Complex From Pyrococcus Woesei
(200 aa)

Score: 50 bits (118), Expect: 0.000110348
Length: 201, Idn/Pos/Gap = 48/90/13 (23%/44%/6%)

Query: 104 VLDANDRYVTECYNRISYLCERSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFRED 163
           V DA +R +    + +  +  +  LP+ V++ A  L R          + VR +   R  
Sbjct:   1 VSDAAERNLAFALSELDRITAQLKLPRHVEEEAARLYR----------EAVR-KGLIRGR  49

Query: 164 ETASIISAALFIACRNEGFPRTFNEISVIVSVAKSRVAAYVKAMEMSIGEAAKISRIRTT 223
              S+++A ++ ACR    PRT +EI+ I  V K  +    + +  ++    K   ++ T
Sbjct:  50 SIESVMAACVYAACRLLKVPRTLDEIADIARVDKKEIGRSYRFIARNLNLTPKKLFVKPT 109

Query: 224 DDFVSRFCSYLEIPNIVRSLVNQVARAAAEKDGIHGRTLVSIAAGAIYFVLLLWRETCPQ 283
            D+V++F   L +   VR    ++   A ++    G++   + A A+Y   LL  E   Q
Sbjct: 110 -DYVNKFADELGLSEKVRRRAIEILDEAYKRGLTSGKSPAGLVAAALYIASLLEGEKRTQ 168

Query: 284 -SIPATLRVSDEALVNRIAEV 303
             +    RV++  + NR  E+
Sbjct: 169 REVAEVARVTEVTVRNRYKEL 189

gb|EAA18727.1| transcription initiation factor iib [Plasmodium yoelii yoelii]
(183 aa)

Score: 49 bits (116), Expect: 0.000208047
Length: 140, Idn/Pos/Gap = 36/64/10 (25%/45%/7%)

Query:  12 DVCGECGSTDLVE-DTKNGDLVCAQCGVVAAELLIDLGHEWRTFEND--DSAYDPNRVGG  68
           + C +C    ++  DT  G  +C  CG+V    ++    EWR F ND    + D NRVG 
Sbjct:  44 NFCPDCKEKGIIICDTSEGTQICNGCGLVIETNILSEEQEWRNFSNDGQSKSNDRNRVGE 103

Query:  69 SINPLLDSGLATSISQGPAGANALNERLARAQSRNVLDANDRYVTECYNRISYLCERSGL 128
           + +  L++ L ++     +      ++L        ++ ND+ +   +N +  +CE   L
Sbjct: 104 ASDIWLENNLTSTTFIKSS------KKLQHLNMMTHINKNDQTLLSAFNILKLICETFFL 157

Query: 129 PQLVKDRACELLR-LYYDHL 147
              V +RA E+ + L   HL
Sbjct: 158 RSNVIERAKEITKELQVSHL 177

emb|CAH02828.1| TF3B_KLULA [Kluyveromyces lactis NRRL Y-1140]
ref|XP_451240.1| TF3B_KLULA [Kluyveromyces lactis]
sp|P46070|TF3B_KLULA Transcription factor IIIB 70 kDa subunit (TFIIIB) (B-related factor) (BRF1)
(556 aa)

Score: 47 bits (112), Expect: 0.0005431
Length: 321, Idn/Pos/Gap = 71/128/55 (22%/39%/17%)

Query:  14 CGECGSTDLVEDTKN--GDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSIN  71
           C  CGSTD V D  N   +L+C  CG+V  E                     N +   + 
Sbjct:  12 CKNCGSTDFVRDISNTTNELICKVCGLVTEE---------------------NSIVSEVT  50

Query:  72 PLLDSGLATSISQGPAGANALNERLARAQSRNVLDANDRYVTECYNRISYLCERSGLPQL 131
               S  A  I      AN  +        +N L + +  +     ++  +     +P+ 
Sbjct:  51 FGEASNGAAVIQGAFVSANQAHPTFMSHSGQNALMSRETTLNNARRKLKAVSYALNIPEY 110

Query: 132 VKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRTFNEISV 191
           V D A +  R     L L  + V+ R      ++ ++I+A L+IACR E   RT + +  
Sbjct: 111 VTDAAFQWYR-----LALSNNFVQGR------KSQNVIAACLYIACRKE---RTHHML-- 154

Query: 192 IVSVAKSRVAAY-VKAMEMSIGEAAKISRIRTTDD--FVSRFCSYLEIPN----IVRSLV 244
           I   ++ +V+ Y + A  + + +  +I ++   D   F+  F   LE+ +    ++R  V
Sbjct: 155 IDFSSRLQVSVYSIGATFLKLAKKLQIVKLPLADPSLFIQHFAEKLELGDKKIKVIRDAV 214

Query: 245 NQVARAAAEKDGIHGRTLVSIAAGAIYFVLLL--WRETCPQSIPATLRVSDEALVNRIAE 302
            ++A+  +      GR    IA   +     +   R T  + I A   V++E L  R+ E
Sbjct: 215 -KLAQTMSRDWMYEGRRPAGIAGACLLLACRMNNLRRTHSE-IVAISHVAEETLQQRLNE 272

Query: 303 VSGITEGVVKTVASRIRQYRD 323
               T   +      ++++RD
Sbjct: 273 FKNTTSAKLS-----VKEFRD 288

pir||A55483 transcription initiation factor IIIB chain BRF - yeast  (Kluyveromyces marxianus var. lactis)
(556 aa)

Score: 46 bits (110), Expect: 0.000918691
Length: 321, Idn/Pos/Gap = 71/128/55 (22%/39%/17%)

Query:  14 CGECGSTDLVEDTKN--GDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSIN  71
           C  CGSTD V D  N   +L+C  CG+V  E                     N +   + 
Sbjct:  12 CKNCGSTDFVRDISNTTNELICKVCGLVTEE---------------------NSIVSELA  50

Query:  72 PLLDSGLATSISQGPAGANALNERLARAQSRNVLDANDRYVTECYNRISYLCERSGLPQL 131
               S  A  I      AN  +        +N L + +  +     ++  +     +P+ 
Sbjct:  51 FGEASNGAAVIQGAFVSANQAHPTFMSHSGQNALMSRETTLNNARRKLKAVSYALNIPEY 110

Query: 132 VKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRTFNEISV 191
           V D A +  R     L L  + V+ R      ++ ++I+A L+IACR E   RT + +  
Sbjct: 111 VTDAAFQWYR-----LALSNNFVQGR------KSQNVIAACLYIACRKE---RTHHML-- 154

Query: 192 IVSVAKSRVAAY-VKAMEMSIGEAAKISRIRTTDD--FVSRFCSYLEIPN----IVRSLV 244
           I   ++ +V+ Y + A  + + +  +I ++   D   F+  F   LE+ +    ++R  V
Sbjct: 155 IDFSSRLQVSVYSIGATFLKLAKKLQIVKLPLADPSLFIQHFAEKLELGDKKIKVIRDAV 214

Query: 245 NQVARAAAEKDGIHGRTLVSIAAGAIYFVLLL--WRETCPQSIPATLRVSDEALVNRIAE 302
            ++A+  +      GR    IA   +     +   R T  + I A   V++E L  R+ E
Sbjct: 215 -KLAQTMSRDWMYEGRRPAGIAGACLLLACRMNNLRRTHSE-IVAISHVAEETLQQRLNE 272

Query: 303 VSGITEGVVKTVASRIRQYRD 323
               T   +      ++++RD
Sbjct: 273 FKNTTSAKLS-----VKEFRD 288

emb|CAA87399.1| TFIIB related subunit of TFIIIB (BRF1) [Kluyveromyces lactis]
(556 aa)

Score: 46 bits (110), Expect: 0.000918691
Length: 321, Idn/Pos/Gap = 71/128/55 (22%/39%/17%)

Query:  14 CGECGSTDLVEDTKN--GDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRVGGSIN  71
           C  CGSTD V D  N   +L+C  CG+V  E                     N +   + 
Sbjct:  12 CKNCGSTDFVRDISNTTNELICKVCGLVTEE---------------------NSIVSELA  50

Query:  72 PLLDSGLATSISQGPAGANALNERLARAQSRNVLDANDRYVTECYNRISYLCERSGLPQL 131
               S  A  I      AN  +        +N L + +  +     ++  +     +P+ 
Sbjct:  51 FGEASNGAAVIQGAFVSANQAHPTFMSHSGQNALMSRETTLNNARRKLKAVSYALNIPEY 110

Query: 132 VKDRACELLRLYYDHLTLGADGVRARARFREDETASIISAALFIACRNEGFPRTFNEISV 191
           V D A +  R     L L  + V+ R      ++ ++I+A L+IACR E   RT + +  
Sbjct: 111 VTDAAFQWYR-----LALSNNFVQGR------KSQNVIAACLYIACRKE---RTHHML-- 154

Query: 192 IVSVAKSRVAAY-VKAMEMSIGEAAKISRIRTTDD--FVSRFCSYLEIPN----IVRSLV 244
           I   ++ +V+ Y + A  + + +  +I ++   D   F+  F   LE+ +    ++R  V
Sbjct: 155 IDFSSRLQVSVYSIGATFLKLAKKLQIVKLPLADPSLFIQHFAEKLELGDKKIKVIRDAV 214

Query: 245 NQVARAAAEKDGIHGRTLVSIAAGAIYFVLLL--WRETCPQSIPATLRVSDEALVNRIAE 302
            ++A+  +      GR    IA   +     +   R T  + I A   V++E L  R+ E
Sbjct: 215 -KLAQTMSRDWMYEGRRPAGIAGACLLLACRMNNLRRTHSE-IVAISHVAEETLQQRLNE 272

Query: 303 VSGITEGVVKTVASRIRQYRD 323
               T   +      ++++RD
Sbjct: 273 FKNTTSAKLS-----VKEFRD 288

gb|AAK38724.1| transcription factor B [Pyrodictium occultum]
sp|Q977X4|TF2B_PYROC Transcription initiation factor IIB (TFIIB)
(310 aa)

Score: 46 bits (109), Expect: 0.00126144
Length: 210, Idn/Pos/Gap = 58/94/28 (27%/44%/13%)

Query:   7 ERDVPDVCGE----CGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYD  62
           +   P   GE    C    +V D + G+ +C   G V  E +ID G EWR +  ++    
Sbjct:   3 KEQAPRASGEKEEGCPPEYIVFDEERGEYICTLTGEVVEETVIDTGPEWRAYTPEERTRR  62

Query:  63 PNRVGGSI-NPLLDSGLATSISQGPAGANALN---------ERLARAQSR-NVLDANDRY 111
            +RVG  + + L D G+ T+IS G   AN             RL R Q++     + ++ 
Sbjct:  63 -SRVGSPLTHTLPDYGILTTIS-GYRDANGRKLEARLRIEASRLRRLQAKLRATTSIEKN 120

Query: 112 VTECYNRISYLCERSGLPQLVKDRACELLRLYYDHLTLGADGVRARARFREDETASIISA 171
           + +    I+ L E   LP+ + D A  + R         A+    R R  E    S+ +A
Sbjct: 121 IEQAAREITRLVEALNLPRGIIDTAMMIYR-------QAAEKGLVRGRSLE----SMAAA 169

Query: 172 ALFIACRNEGFPRTFNEISVIVSVAKSRVA 201
           A++ ACR  G PR+ ++I+ +V   +  VA
Sbjct: 170 AVYAACRIRGIPRSIDDIAEVVKGGRKEVA 199

ref|NP_142794.1| transcription initiation factor IIB [Pyrococcus horikoshii OT3]
dbj|BAA29958.1| 208aa long hypothetical transcription initiation factor IIB [Pyrococcus horikoshii OT3]
pir||D71137 probable transcription initiation factor IIB - Pyrococcus horikoshii
(208 aa)

Score: 45 bits (107), Expect: 0.0018828
Length: 146, Idn/Pos/Gap = 37/67/15 (25%/45%/10%)

Query: 167 SIISAALFIACRNEGFPRTFNEISVIVSVAKSRVAAYVKAMEMSIGEAAKISRIRTTDDF 226
           S+ +A ++I+CR    PRT +EI+ +    K  +A   + +   +G ++K   IR  + +
Sbjct:  64 SVAAACIYISCRLYKVPRTLDEIAKVAKEDKKVIARVYRLVVKKLGLSSKDMLIR-PEYY 122

Query: 227 VSRFCSYLEIPNIVRSLVNQVARAAAEKDGIHGRTLVSIAAGAIYFVLLLWRETCPQSIP 286
           + +F   LE+   V+    ++   A +K    G+  + +AA  +Y   LL  E   Q   
Sbjct: 123 IDKFADELEVSERVKRRALRLLNEAKDKGITSGKNPLGLAASILYIASLLEGERRTQ--- 179

Query: 287 ATLRVSDEALVNRIAEVSGITEGVVK 312
                        IA V+GITE  ++
Sbjct: 180 -----------KEIARVAGITEVTIR 194

gb|EAK91571.1| likely transcription factor TFIIB fragment [Candida albicans SC5314]
gb|EAK91560.1| likely transcription factor TFIIB fragment [Candida albicans SC5314]
(176 aa)

Score: 45 bits (106), Expect: 0.00267298
Length: 177, Idn/Pos/Gap = 40/74/29 (22%/41%/16%)

Query: 169 ISAALFIACRNEGFPRTFNEISVIVSVAKSRVAAYVKAME-------------MSIGEAA 215
           ++A + + CR     RT  EI  + +VA  ++A     ++              SI +  
Sbjct:   1 MAATILLGCRRADVGRTLEEIRALTNVATKQIAKVTGLIKKIIRSHLNNDDASTSIVDET  60

Query: 216 KISRIRTTDDFVSRFCSYLEIPNIVRSLVNQVARAAAEKDGIHGRTLVSIAAGAIYFVLL 275
                 + +D + RFCS+L +   + S    VAR   +   + GR+  +IAA +I+    
Sbjct:  61 SSLTTHSAEDLIRRFCSHLGLSLAITSASEYVARKCHDLGVLAGRSPTTIAATSIFL--- 117

Query: 276 LWRETCPQSIPATLRVSDEALV-NRIAEVSGITEGVVKTVASRIRQYRDRGLLPPDW 331
                      A   + D  L   +I + +G++ G +K  + +I Q   + L+ P W
Sbjct: 118 -----------AAKSLGDTKLTQQQIRDKTGVSIGTIKN-SYKILQENAKDLIDPAW 162

emb|CAF92977.1| unnamed protein product [Tetraodon nigroviridis]
(165 aa)

Score: 44 bits (104), Expect: 0.00402304
Length: 176, Idn/Pos/Gap = 49/70/37 (27%/39%/21%)

Query:  13 VCGECGSTDLVEDTKNGDLVCAQCGVVAAELLIDLGHEWRTFENDDSAYDPNRV---GGS  69
           VCG CG +D+  D   G  VC  CG V  + +I    ++       S+     V   G  
Sbjct:   5 VCGTCGGSDIDVDQARGSAVCTDCGSVLEDNIIVSEVQFVEGSGGVSSAVGQFVSADGPV  64

Query:  70 INPLLDSGLATSISQGPAGANALNERLARAQSRNVLDANDRYVTECYNRISYLCERSGLP 129
             PLL SG  TS+            + +RAQ+   L    R       +I +L  +  L 
Sbjct:  65 KAPLLGSGFHTSVG-----------KESRAQT---LQGGKR-------QIQHLGSQLQLN 103

Query: 130 QLVKDRACELLRLYYD-HLTLGADGVRARARFREDETASIISAALFIACRNEGFPR 184
           Q   D A    ++    HLT G             +T  +I+A L++ CR EG PR
Sbjct: 104 QHCLDTAFNFFKMVVSKHLTRGR------------KTEHVIAACLYLVCRTEGTPR 147

Cyanidioschyzon merolae Genome Project