BLAST output

CMM044C (425 aa)
by blastp 2.2.10 [Oct-19-2004] against nr [Apr-30-2005] (XML result)


		hypothetical protein CNBD3420 [Cryptococcus neoformans var. neoformans B-3501A]
		putative centromere/microtubule binding protein [Oryza sativa]
		ENSANGP00000017710 [Anopheles gambiae str. PEST]
		nucleolar protein AfCbf5p
		putative centromere/microtubule binding protein [Oryza sativa (japonica cultivar-group)]
		Dyskerin (Nucleolar protein NAP57)
		Centromere/microtubule binding protein CBF5 (Centromere-binding factor 5) (Small nucleolar RNP protein CBF5) (H/ACA snoRNP protein CBF5) (p64')
		unnamed protein product [Yarrowia lipolytica CLIB99]
		CG3333-PA, isoform A [Drosophila melanogaster]
		rRNA pseudouridine synthase [Emericella nidulans]
		AT23018p [Drosophila melanogaster]
		Dkc1 protein [Danio rerio]
		AAL007Cp [Ashbya gossypii ATCC 10895]
		minifly protein [Drosophila melanogaster]
		similar to DYSKERIN [Mus musculus]
		hypothetical protein [Gallus gallus]
		CBF5_EMENI Centromere/microtubule binding protein CBF5 (Centromere-binding factor 5) (Nucleolar protein CBF5) [Aspergillus nidulans FGSC A4]
		likely snoRNP-associated pseudouridylate synthase [Candida albicans SC5314]
		dyskeratosis congenita 1, dyskerin [Rattus norvegicus]
		dyskerin [Homo sapiens]
		Cbf5p homolog
		dyskerin [Homo sapiens]
		hypothetical protein DDB0204297 [Dictyostelium discoideum]
		Hypothetical protein K01G5.5 [Caenorhabditis elegans]
		nuclear protein NAP57
		Hypothetical protein CBG18316 [Caenorhabditis briggsae]
		Dyskerin [Homo sapiens]
		putative protein [Arabidopsis thaliana]
		Cbf5p [Euglena gracilis]
		probable CENTROMERE/MICROTUBULE BINDING PROTEIN CBF5 [Neurospora crassa]
		unnamed protein product [Debaryomyces hansenii CBS767]
		hypothetical protein UM00685.1 [Ustilago maydis 521]
		unnamed protein product [Candida glabrata CBS138]
		CBF5_KLULA [Kluyveromyces lactis NRRL Y-1140]
		hypothetical protein Chro.30435 [Cryptosporidium hominis]
		Cbf5p; centromere-binding factor 5 like PUA domain containing protein with a type I pseudouridine synthase domain, transcript identified by EST [Cryptosporidium parvum]
		SPAC29A4.04c [Schizosaccharomyces pombe]
		putative kinetochore protein [Hordeum vulgare subsp. vulgare]
		hypothetical protein FG07206.1 [Gibberella zeae PH-1]
		probable dyskerin [Leishmania major]
		hypothetical protein PF14_0174 [Plasmodium falciparum 3D7]
		unknown protein-related [Plasmodium yoelii yoelii]
		PREDICTED: similar to Dyskerin (Nucleolar protein NAP57) (CBF5 homolog) [Canis familiaris]
		conserved hypothetical protein [Plasmodium berghei]
		centromere/microtubule binding protein cbf5, putative [Entamoeba histolytica HM-1:IMSS]
		unknown [Schistosoma japonicum]
		similar to CG3333-PA [Apis mellifera]
		CENTROMERE/MICROTUBULE BINDING PROTEIN [Encephalitozoon cuniculi GB-M1]
		GLP_576_9913_8648 [Giardia lamblia ATCC 50803]
		PREDICTED: similar to Dyskerin (Nucleolar protein NAP57) (CBF5 homolog) [Pan troglodytes]
		unnamed protein product [Tetraodon nigroviridis]
		truB tRNA pseudouridine synthase II [Pyrococcus abyssi GE5]
		COG0130: Pseudouridine synthase [Methanosarcina barkeri str. fusaro]
		Pseudouridine synthase of the TruB family [Methanopyrus kandleri AV19]
		centromere/microtubule binding protein [Pyrococcus horikoshii OT3]
		centromere/microtubule-binding protein (cbf5) [Archaeoglobus fulgidus DSM 4304]
		rRNA pseudouridine synthase [Methanosarcina acetivorans C2A]
		hypothetical centromere binding protein/pseudouridine synthase [Pyrococcus furiosus DSM 3638]
		COG0130: Pseudouridine synthase [Methanococcoides burtonii DSM 6242]
		tRNA pseudouridine synthase B [Thermococcus kodakaraensis KOD1]
		tRNA pseudouridine synthase [Methanosarcina mazei Go1]
		centromere/microtubule-binding protein [Methanothermobacter thermautotrophicus str. Delta H]
		centromere/microtubule-binding protein (cbf5) [Methanocaldococcus jannaschii DSM 2661]
		PREDICTED: similar to Dyskerin (Nucleolar protein NAP57) (CBF5 homolog) [Gallus gallus]
		conserved hypothetical protein [Plasmodium chabaudi]
		PREDICTED: similar to DYSKERIN [Bos taurus]
		tRNA pseudouridine synthase B [Pyrobaculum aerophilum str. IM2]
		pseudouridine syntase related protein [Methanococcus maripaludis S2]
		hypothetical protein NEQ454 [Nanoarchaeum equitans Kin4-M]
		tRNA pseudouridine synthase subunit B (truB) [Sulfolobus solfataricus P2]
		nucleolar protein [Aeropyrum pernix K1]
		Pseudouridine synthase (dyskerin-related) [Thermoplasma volcanium GSS1]
		Sus [Halobacterium sp. NRC-1]
		tRNA pseudouridine 55 synthase [Picrophilus torridus DSM 9790]
		centromere/microtubule binding protein-like protein [Antonospora locustae]
		Probable tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
		tRNA pseudouridine synthase B [Haloarcula marismortui ATCC 43049]
		hypothetical centromere/microtubule binding protein cbf5 [Sulfolobus tokodaii str. 7]
		dyskerin (nucleolar protein Nap57) related protein [Thermoplasma acidophilum DSM 1728]
		unknown [Schistosoma japonicum]
		COG0130: Pseudouridine synthase [Ferroplasma acidarmanus]
		hypothetical protein PC300741.00.0 [Plasmodium chabaudi]
		hypothetical protein MG07518.4 [Magnaporthe grisea 70-15]
		tRNA pseudouridine 55 synthase [Bacillus subtilis subsp. subtilis str. 168]
		COG0130: Pseudouridine synthase [Exiguobacterium sp. 255-15]
		TruB [Bacillus licheniformis ATCC 14580]
		tRNA pseudouridine 55 synthase [Bacillus licheniformis ATCC 14580]
		tRNA pseudouridine 5S synthase [Geobacillus kaustophilus HTA426]
		tRNA pseudouridine synthase B [Streptococcus pneumoniae TIGR4]
		COG0130: Pseudouridine synthase [Pediococcus pentosaceus ATCC 25745]
		tRNA pseudouridine synthase B [Streptococcus thermophilus CNRZ1066]
		COG0130: Pseudouridine synthase [Streptococcus thermophilus LMD-9]
		tRNA pseudouridine synthase B [Streptococcus thermophilus LMG 18311]
		tRNA pseudouridine synthase B [Neisseria meningitidis Z2491]
		tRNA pseudouridine 5S synthase [Streptococcus pneumoniae R6]
		Unknown [Streptococcus agalactiae NEM316]
		tRNA pseudouridine 55 synthase [Symbiobacterium thermophilum IAM 14863]
		unknown protein [synthetic construct]
		tRNA pseudouridine synthetase B [Francisella tularensis subsp. tularensis Schu 4]
		tRNA pseudouridine synthase B [Listeria monocytogenes str. 4b F2365]
		tRNA pseudouridine synthase B [Listeria monocytogenes str. 4b H7858]
		truB [Listeria innocua Clip11262]
		tRNA pseudouridine synthase B [Listeria monocytogenes str. 1/2a F6854]
		tRNA pseudouridine synthase B [Neisseria meningitidis MC58]
		putative tRNA pseudouridine synthase B [Corynebacterium efficiens YS-314]
		hypothetical protein lmo1328 [Listeria monocytogenes EGD-e]
		tRNA-pseudouridine 5S synthase [Oceanobacillus iheyensis HTE831]
		tRNA pseudouridine synthase B [Bacillus anthracis str. Sterne]
		putative tRNA pseudouridine synthase B [Neisseria gonorrhoeae FA 1090]
		pseudouridylate synthase [Lactobacillus plantarum WCFS1]
		tRNA pseudouridine synthase B (tRNA-pseudouridine synthase I) [Bacillus cereus ZK]
		tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
		COG0130: Pseudouridine synthase [Thermobifida fusca]
		tRNA pseudouridine 55 synthase [Azoarcus sp. EbN1]
		tRNA pseudouridine 55 synthase [Thermotoga maritima MSB8]
		COG0130: Pseudouridine synthase [Cytophaga hutchinsonii]
		COG0130: Pseudouridine synthase [Microbulbifer degradans 2-40]
		COG0130: Pseudouridine synthase [Lactococcus lactis subsp. cremoris SK11]
		COG0130: Pseudouridine synthase [Clostridium thermocellum ATCC 27405]
		tRNA synthase-like protein [Arabidopsis thaliana]
		tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
		tRNA pseudouridine synthase B [Bacillus thuringiensis serovar konkukian str. 97-27]
		COG0130: Pseudouridine synthase [Streptococcus suis 89/1591]
		tRNA pseudouridine synthase B [Buchnera aphidicola str. Bp (Baizongia pistaciae)]
		tRNA pseudouridine synthase B [Bacillus cereus G9241]
		PROBABLE TRNA PSEUDOURIDINE SYNTHASE B TRUB (TRNA PSEUDOURIDINE 55 SYNTHASE) (PSI55 SYNTHASE) (PSEUDOURIDYLATE SYNTHASE) (URACIL HYDROLYASE) [Mycobacterium tuberculosis H37Rv]
		Chain B, Structure Of Trna Psi55 Pseudouridine Synthase (Trub)
		tRNA pseudouridine synthase B [Bacillus cereus ATCC 10987]
		tRNA pseudouridine synthase B [Clostridium tetani E88]
		tRNA pseudouridine synthase B [Streptococcus pyogenes MGAS10394]
		TRNA PSEUDOURIDINE SYNTHASE B [Corynebacterium glutamicum ATCC 13032]
		tRNA pseudouridine synthase B [Corynebacterium diphtheriae NCTC 13129]
		putative tRNA pseudouridine 5S synthase [Streptococcus mutans UA159]
		putative tRNA pseudouridine 55 synthase [Streptococcus pyogenes SSI-1]
		tRNA pseudouridine synthase B [Propionibacterium acnes KPA171202]
		COG0130: Pseudouridine synthase [Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365]
		probable tRNA pseudouridine synthase B [Desulfotalea psychrophila LSv54]
		tRNA pseudouridine synthase B [Leifsonia xyli subsp. xyli str. CTCB07]
		TruB [Mycobacterium avium subsp. paratuberculosis str. k10]
		tRNA pseudouridine 55 synthase [Mycobacterium leprae TN]
		tRNA pseudouridine synthase B [Lactococcus lactis subsp. lactis Il1403]
		tRNA pseudouridine synthase B [Burkholderia pseudomallei K96243]
		putative tRNA synthase [Oryza sativa (japonica cultivar-group)]
		probable tRNA pseudouridine synthase [Streptomyces coelicolor A3(2)]
		COG0130: Pseudouridine synthase [Ralstonia metallidurans CH34]
		COG0130: Pseudouridine synthase [Burkholderia cepacia R18194]
		putative tRNA synthase [Oryza sativa]
		tRNA pseudouridine synthase B [Bacillus clausii KSM-K16]
		tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
		tRNA pseudouridine synthase B [Geobacter sulfurreducens PCA]
		putative tRNA pseudouridine 55 synthase [Synechococcus sp. WH 8102]
		Pseudouridine synthase [Clostridium acetobutylicum ATCC 824]
		putative tRNA pseudouridine synthase B [Staphylococcus aureus subsp. aureus MRSA252]
		putative tRNA pseudouridine synthase [Streptomyces avermitilis MA-4680]
		tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
		COG0130: Pseudouridine synthase [Burkholderia fungorum LB400]
		tRNA pseudouridine 55 synthase [Staphylococcus aureus subsp. aureus COL]
		COG0130: Pseudouridine synthase [Polaromonas sp. JS666]
		COG0130: Pseudouridine synthase [Haemophilus somnus 2336]
		tRNA pseudouridine 5S synthase [Staphylococcus aureus subsp. aureus Mu50]
		putative tRNA pseudouridine synthase B [Staphylococcus aureus subsp. aureus MSSA476]
		tRNA pseudouridine synthase B [Silicibacter pomeroyi DSS-3]
		COG0130: Pseudouridine synthase [Rubrobacter xylanophilus DSM 9941]
		COG0130: Pseudouridine synthase [Geobacter metallireducens GS-15]
		tRNA pseudouridine 55 synthase [Haemophilus influenzae Rd KW20]
		COG0130: Pseudouridine synthase [Ehrlichia canis str. Jake]
		tRNA pseudouridine synthase B [Synechococcus elongatus PCC 6301]
		COG0130: Pseudouridine synthase [Ralstonia eutropha JMP134]
		tRNA pseudouridine 5S synthase [Staphylococcus epidermidis ATCC 12228]
		COG0130: Pseudouridine synthase [Rubrivivax gelatinosus PM1]
		tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
		Putative tRNA pseudouridine synthase [Prochlorococcus marinus str. MIT 9313]
		COG0130: Pseudouridine synthase [Actinobacillus pleuropneumoniae serovar 1 str. 4074]
		COG0130: Pseudouridine synthase [Haemophilus influenzae 86-028NP]
		COG0130: Pseudouridine synthase [Enterococcus faecium]
		PROBABLE TRNA PSEUDOURIDINE SYNTHASE B PROTEIN [Ralstonia solanacearum]
		COG0130: Pseudouridine synthase [Pseudomonas aeruginosa UCBPP-PA14]
		tRNA pseudouridine 55 synthase [Pseudomonas aeruginosa PAO1]
		COG0130: Pseudouridine synthase [Haemophilus influenzae R2846]
		COG0130: Pseudouridine synthase [Haemophilus influenzae R2866]
		tRNA pseudouridine synthase B [Haemophilus ducreyi 35000HP]
		tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (pseudouridylate synthase) (uracil hydrolyase) (P35 protein) [Photorhabdus luminescens subsp. laumondii TTO1]
		tRNA pseudouridine 55 synthase [Acinetobacter sp. ADP1]
		Pseudouridine synthase [Vibrio vulnificus CMCP6]
		tRNA pseudouridine synthase B [Bordetella parapertussis 12822]
		tRNA pseudouridine synthase B [Yersinia pseudotuberculosis IP 32953]
		tRNA pseudouridine 55 synthase [Chlamydophila pneumoniae TW-183]
		putative tRNA pseudouridine synthase B [Ehrlichia ruminantium str. Welgevonden]
		COG0130: Pseudouridine synthase [Burkholderia cepacia R1808]
		tRNA pseudouridine synthase B [Bordetella bronchiseptica RB50]
		COG0130: Pseudouridine synthase [Streptococcus pyogenes M49 591]
		COG0130: Pseudouridine synthase [Moorella thermoacetica ATCC 39073]
		tRNA pseudouridine 55 synthase [Vibrio cholerae O1 biovar eltor str. N16961]
		tRNA pseudouridine synthase B [Xanthomonas campestris pv. campestris str. ATCC 33913]
		putative tRNA pseudouridine synthase [Oryza sativa (indica cultivar-group)]
		tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
		tRNA pseudouridine 55 synthase [Aquifex aeolicus VF5]
		tRNA pseudouridine 5S synthase [Idiomarina loihiensis L2TR]
		COG0130: Pseudouridine synthase [Trichodesmium erythraeum IMS101]
		yhbA [Yersinia enterocolitica]
		putative tRNA pseudouridine synthase [Nocardia farcinica IFM 10152]
		COG0130: Pseudouridine synthase [Oenococcus oeni PSU-1]
		tRNA Pseudouridine Synthase [Chlamydia trachomatis D/UW-3/CX]
		TruB [Pasteurella multocida subsp. multocida str. Pm70]
		tRNA pseudouridine synthase B [Chlamydophila abortus S26/3]
		putative tRNA pseudouridine 55 synthase [Streptococcus pyogenes MGAS315]
		tRNA pseudouridine synthase B [Gloeobacter violaceus PCC 7421]
		COG0130: Pseudouridine synthase [Methylobacillus flagellatus KT]
		COG0130: Pseudouridine synthase [Brevibacterium linens BL2]
		tRNA pseudouridine synthase B [Dehalococcoides ethenogenes 195]
		tRNA pseudouridine synthase B [Xanthomonas oryzae pv. oryzae KACC10331]
		COG0130: Pseudouridine synthase [Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293]
		tRNA pseudouridine 55 synthase [Vibrio parahaemolyticus RIMD 2210633]
		tRNA pseudouridine synthase B [Buchnera aphidicola str. Sg (Schizaphis graminum)]
		TruB protein [Mannheimia succiniciproducens MBEL55E]
		TruB [Flavobacterium johnsoniae]
		tRNA pseudouridine synthase B [Erwinia carotovora subsp. atroseptica SCRI1043]
		COG0130: Pseudouridine synthase [Nostoc punctiforme PCC 73102]
		tRNA pseudouridine synthase B [Xanthomonas axonopodis pv. citri str. 306]
		COG0130: Pseudouridine synthase [Crocosphaera watsonii WH 8501]
		tRNA pseudouridine 55 synthase [Salmonella enterica subsp. enterica serovar Typhi Ty2]
		tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
		COG0130: Pseudouridine synthase [Silicibacter sp. TM1040]
		COG0130: Pseudouridine synthase [Azotobacter vinelandii]
		tRNA pseudouridine synthase B [Tropheryma whipplei TW08/27]
		Pseudouridine synthase [Thermoanaerobacter tengcongensis MB4]
		tRNA pseudouridine 55 synthase (psi55 synthase) (p35 protein) [Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150]
		tRNA pseudouridine synthase B [Chlorobium tepidum TLS]
		tRNA pseudouridine synthase B [Heliobacillus mobilis]
		tRNA pseudouridine 55 synthase [Buchnera aphidicola str. APS (Acyrthosiphon pisum)]
		tRNA pseudouridine 55 synthase [Synechocystis sp. PCC 6803]
		tRNA pseudouridine 5S synthase [Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67]
		tRNA pseudouridine synthase B [Tropheryma whipplei str. Twist]
		COG0130: Pseudouridine synthase [Rickettsia rickettsii]
		tRNA pseudouridine synthase B [Thermosynechococcus elongatus BP-1]
		probable tRNA pseudouridine synthase B [Parachlamydia sp. UWE25]
		COG0130: Pseudouridine synthase [Anabaena variabilis ATCC 29413]
		tRNA pseudouridine synthase B [Lactobacillus johnsonii NCC 533]
		tRNA pseudouridine synthase B [Mycoplasma mycoides subsp. mycoides SC str. PG1]
		tRNA pseudouridine synthase B [Bacillus cereus ATCC 14579]
		tRNA pseudouridine synthase B [Xylella fastidiosa Temecula1]
		putative tRNA pseudouridine 5S synthase [Photobacterium profundum SS9]
		Putative tRNA pseudouridine 55 synthase [Prochlorococcus marinus subsp. pastoris str. CCMP1986]
		Pseudouridine synthase.; Uracil hydrolyase.; tRNA pseudouridylate synthase B [Rickettsia typhi str. Wilmington]
		tRNA pseudouridine 55 synthase [Rickettsia conorii str. Malish 7]
		COG0130: Pseudouridine synthase [Lactobacillus gasseri]
		COG0130: Pseudouridine synthase [Pseudomonas fluorescens PfO-1]
		Pseudouridine synthase [Prochlorococcus marinus subsp. marinus str. CCMP1375]
		tRNA pseudouridine 55 synthase [Rickettsia sibirica 246]
		COG0130: Pseudouridine synthase [Psychrobacter sp. 273-4]
		COG0130: Pseudouridine synthase [Kineococcus radiotolerans SRS30216]
		tRNA pseudouridine 55 synthase [Chromobacterium violaceum ATCC 12472]
		tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
		COG0130: Pseudouridine synthase [Pseudomonas syringae pv. syringae B728a]
		tRNA pseudouridine synthase B [Xylella fastidiosa 9a5c]
		Chain A, Crystal Structure Of The E. Coli Pseudouridine Synthase Trub Bound To A T Stem-Loop Rna
		COG0130: Pseudouridine synthase [Xylella fastidiosa Ann-1]
		COG0130: Pseudouridine synthase [Chloroflexus aurantiacus]
		COG0130: Pseudouridine synthase [Xylella fastidiosa Dixon]
		COG0130: Pseudouridine synthase [Thiobacillus denitrificans ATCC 25259]
		COG0130: Pseudouridine synthase [Rickettsia akari str. Hartford]
		tRNA pseudouridine 5S synthase [Shigella flexneri 2a str. 301]
		tRNA pseudouridine 55 synthase [Mesorhizobium loti MAFF303099]
		tRNA pseudouridine synthase B [Escherichia coli CFT073]
		tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
		tRNA pseudouridine synthase B [Vibrio fischeri ES114]
		tRNA pseudouridine synthase B [Lactobacillus acidophilus NCFM]
		tRNA pseudouridine synthase B [Nitrosomonas europaea ATCC 19718]
		COG0130: Pseudouridine synthase [Lactobacillus casei ATCC 334]
		tRNA pseudouridine synthase B [Bacteroides thetaiotaomicron VPI-5482]
		tRNA pseudouridine 55 synthase, putative [Deinococcus radiodurans]
		tRNA pseudouridine synthase B [Bacteroides fragilis YCH46]
		COG0130: Pseudouridine synthase [Magnetospirillum magnetotacticum MS-1]
		tRNA pseudouridine synthase B [Bartonella henselae str. Houston-1]
		P35 [Escherichia coli]
		pseudouridine synthase [Onion yellows phytoplasma OY-M]
		hypothetical protein AGR_C_127 [Agrobacterium tumefaciens str. C58]
		tRNA pseudouridine 5S synthase [Candidatus Blochmannia floridanus]
		tRNA pseudouridine synthase B [Bartonella quintana str. Toulouse]
		PROBABLE TRNA PSEUDOURIDINE SYNTHASE B PROTEIN [Sinorhizobium meliloti]
		tRNA pseudouridine 5S synthase [Mesoplasma florum L1]
		COG0130: Pseudouridine synthase [Rhodobacter sphaeroides 2.4.1]
		tRNA pseudouridine synthase B [Legionella pneumophila str. Paris]
		putative tRNA pseudouridine 55 synthase [Rhodopseudomonas palustris CGA009]
		tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
		tRNA pseudouridine synthase B [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
		tRNA pseudouridine synthase subunit A (truB) [Sulfolobus solfataricus P2]
		COG0130: Pseudouridine synthase [Dechloromonas aromatica RCB]
		TRNA PSEUDOURIDINE SYNTHASE B [Brucella melitensis 16M]
		tRNA pseudouridine synthase B [Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough]
		tRNA pseudouridine synthase B [Brucella abortus biovar 1 str. 9-941]
		tRNA pseudouridine synthase B [Legionella pneumophila str. Lens]
		COG0130: Pseudouridine synthase [Magnetospirillum magnetotacticum MS-1]
		tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
		COG0130: Pseudouridine synthase [Mesorhizobium sp. BNC1]
		tRNA pseudouridine synthase B [Caulobacter crescentus CB15]
		tRNA pseudouridine synthase B [Bdellovibrio bacteriovorus HD100]
		tRNA pseudouridine 5S synthase [Mycoplasma penetrans HF-2]
		nucleolar protein [Aeropyrum pernix K1]
		TruB pseudouridine (psi) synthase homolog 1 [Mus musculus]
		hypothetical protein [Lactococcus lactis]
		tRNA pseudouridine synthase B [Fusobacterium nucleatum subsp. vincentii ATCC 49256]
		PREDICTED: TruB pseudouridine (psi) synthase homolog 1 (E. coli) (predicted) [Rattus norvegicus]
		COG0130: Pseudouridine synthase [Desulfovibrio desulfuricans G20]
		TruB [Mycoplasma gallisepticum R]
		tRNA pseudouridine 55 synthase [Bradyrhizobium japonicum USDA 110]
		TruB pseudouridine (psi) synthase homolog 1 variant [Homo sapiens]
		hypothetical protein [Homo sapiens]
		TRNA PSEUDOURIDINE SYNTHASE B (TRNA PSEUDOURIDINE 55 SYNTHASE) (PSI55 SYNTHASE) (PSEUDOURIDYLATE SYNTHASE) (URACIL HYDROLYASE) [Mycoplasma pulmonis UAB CTIP]
		hypothetical centromere/microtubule binding protein cbf5 [Sulfolobus tokodaii str. 7]
		PREDICTED: similar to TruB pseudouridine (psi) synthase homolog 1 [Gallus gallus]
		tRNA pseudoridine 55 synthase [Synechococcus sp. PCC 7942]
		RIKEN cDNA 2610009I02 [Mus musculus]
		tRNA pseudoridine 55 synthase [Synechococcus sp.]
		tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
		tRNA pseudouridine synthase B [Gluconobacter oxydans 621H]
		tRNA pseudouridine synthase B [Fusobacterium nucleatum subsp. nucleatum ATCC 25586]
		PREDICTED: similar to Cadherin-13 precursor (Truncated-cadherin) (T-cadherin) (T-cad) (Heart-cadherin) (H-cadherin) (P105) [Canis familiaris]
		2610009I02Rik protein [Mus musculus]
		PREDICTED: similar to TruB pseudouridine (psi) synthase homolog 1 [Canis familiaris]
		tRNA pseudouridine synthase B, interruption-N [Methylococcus capsulatus str. Bath]
		PREDICTED: similar to TruB pseudouridine (psi) synthase homolog 1 [Pan troglodytes]
		tRNA pseudouridine 55 synthase [Borrelia garinii PBi]
		tRNA pseudouridine 55 synthase [Ureaplasma parvum serovar 3 str. ATCC 700970]
		COG0130: Pseudouridine synthase [Bifidobacterium longum DJO10A]
		tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
		COG0130: Pseudouridine synthase [Rhodospirillum rubrum]
		tRNA pseudouridine synthase B [Mycoplasma mobile 163K]
		tRNA pseudouridine synthase B [Rhodopirellula baltica SH 1]
		Orp [Pseudomonas aeruginosa]
		ORF7 [Bacillus subtilis]
		putative pseudouridylate synthase [Guillardia theta]
		COG0130: Pseudouridine synthase [Novosphingobium aromaticivorans DSM 12444]
		tRNA-pseudouridine synthase (EC 5.4.99.-) - Acinetobacter calcoaceticus (fragment)
		TruB pseudouridine (psi) synthase homolog 1 [Mus musculus]
		tRNA pseudouridine synthase B, putative [Campylobacter coli RM2228]
		tRNA pseudouridine synthase B [Helicobacter hepaticus ATCC 51449]
		tRNA pseudouridine 55 synthase [Thermus thermophilus HB27]
		tRNA pseudouridine synthase B [Mycoplasma hyopneumoniae 232]
		TRNA PSEUDOURIDINE 55 SYNTHASE (truB) [Rickettsia prowazekii str. Madrid E]
		tRNA pseudouridine synthase B [Campylobacter jejuni RM1221]
		tRNA pseudouridine synthase, putative [Plasmodium berghei]
		tRNA pseudouridine synthase B [Campylobacter jejuni subsp. jejuni NCTC 11168]
		tRNA pseudouridine 55 synthase (truB) [Borrelia burgdorferi B31]
		tRNA pseudouridine 55 synthase (truB) [Treponema pallidum subsp. pallidum str. Nichols]
		hypothetical protein PB301155.00.0 [Plasmodium berghei]
		tRNA pseudouridine synthase, putative [Plasmodium falciparum 3D7]
		tRNA pseudouridine synthase B, putative [Campylobacter upsaliensis RM3195]
		tRNA pseudouridine synthase B [Treponema denticola ATCC 35405]
		COG0130: Pseudouridine synthase [Magnetococcus sp. MC-1]
		tRNA pseudouridine synthase B [Erythrobacter litoralis HTCC2594]
		tRNA pseudouridine synthase, putative [Plasmodium chabaudi]
		COG0130: Pseudouridine synthase [Geobacter metallireducens GS-15]
		TRNA PSEUDOURIDINE SYNTHASE B [Wolinella succinogenes DSM 1740]
		hypothetical protein [Pongo pygmaeus]
		Maa2 protein [Chlamydomonas reinhardtii]
		iron-sulfur protein [Pyrococcus furiosus DSM 3638]
		hypothetical protein AN0072.2 [Aspergillus nidulans FGSC A4]
		TruB family pseudouridylate synthase, putative [Plasmodium yoelii yoelii]

gb|EAL21288.1| hypothetical protein CNBD3420 [Cryptococcus neoformans var. neoformans B-3501A]
gb|AAW42892.1| centromere/microtubule binding protein cbf5, putative [Cryptococcus neoformans var. neoformans JEC21]
ref|XP_570199.1| centromere/microtubule binding protein cbf5, putative [Cryptococcus neoformans var. neoformans JEC21]
(503 aa)

Score: 579 bits (1493), Expect: 4.69973e-164
Length: 403, Idn/Pos/Gap = 286/336/9 (70%/83%/2%)

Query:   1 MTPKSSASLAEQQRS-----LSFQIPSDAGENGLSTDSWPLLLKNYDRLNVRTTHYTPIP  55
           M   SS++L + Q S       F I S++    L T  WPLLLKNYD+L VR++H+TPIP
Sbjct:   1 MAVASSSTLTDSQVSKIQQDSDFSIKSESVTPKLDTSQWPLLLKNYDKLLVRSSHFTPIP  60

Query:  56 DAGYSPLKRPIQEYIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCL 115
            +G SPLKR +Q Y++SGVINLDKP+NPSSHEVVAW+KRILRVEKTGHSGTLDP+VTGCL
Sbjct:  61 -SGISPLKRDLQTYVKSGVINLDKPSNPSSHEVVAWLKRILRVEKTGHSGTLDPKVTGCL 119

Query: 116 IVCIERATRLVKSQQSAGKEYVAVLRLHGMRPELDEATVRRAIETLTGPLYQRPPLISAV 175
           IVCI+RATRLVKSQQ AGKEYV V+R H      DE  + RA+ETLTG L+QRPPLISAV
Sbjct: 120 IVCIDRATRLVKSQQGAGKEYVCVVRFHDKLQ--DEKALPRALETLTGALFQRPPLISAV 177

Query: 176 KRQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVR 235
           KRQLR+RTIYESKL+EYD +R L +FWVSCEAGTYIRTLCVHLGLLLGVG HMQELRRVR
Sbjct: 178 KRQLRVRTIYESKLIEYDNERNLGVFWVSCEAGTYIRTLCVHLGLLLGVGAHMQELRRVR 237

Query: 236 SGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPLESLLVHHKRIVIKDSCVNAVC 295
           SG+  E D +V+MHDVLDAQWL+D T+DESYLRRVI+PLESLLV++KRIV+KDS VNA+C
Sbjct: 238 SGITGENDDIVSMHDVLDAQWLYDNTRDESYLRRVIRPLESLLVNYKRIVVKDSAVNAIC 297

Query: 296 YGAKLMLPGVLRYENDIECGEEVVIMTTKGEAVALAIAHMSTSEIASCDHGVVARIKRVV 355
           YGAKLM+PG+LRYE DIE  EEVV+MTTKGEA+A+ IA MST ++ASCDHGVVA++KR +
Sbjct: 298 YGAKLMIPGLLRYEADIEVNEEVVLMTTKGEAIAIGIAQMSTVDLASCDHGVVAKVKRCI 357

Query: 356 MERDLYPRRWGLGPVASRKKAMIQRGELDKHGRPNEH-TPSDW 397
           M RDLYPR+WGLGP A  KK MI++GELDK+G+P E  TP  W
Sbjct: 358 MNRDLYPRKWGLGPKAQEKKKMIKKGELDKYGKPIEGVTPQQW 400

ref|NP_909483.1| putative centromere/microtubule binding protein [Oryza sativa]
gb|AAG46137.1| putative centromere/microtubule binding protein [Oryza sativa]
(591 aa)

Score: 576 bits (1485), Expect: 3.66007e-163
Length: 371, Idn/Pos/Gap = 274/318/3 (73%/85%/0%)

Query:  29 LSTDSWPLLLKNYDRLNVRTTHYTPIPDAGYSPLKRPIQEYIRSGVINLDKPANPSSHEV  88
           L T +WPLLLKNYDRLNVRT HYTP+P AG+SPLKRPI EY+R GVINLDKP+NPSSHEV
Sbjct:  65 LDTSAWPLLLKNYDRLNVRTGHYTPLP-AGHSPLKRPIAEYLRYGVINLDKPSNPSSHEV 123

Query:  89 VAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAGKEYVAVLRLHGMRPE 148
           VAWIKR+LRVEKTGHSGTLDP+VTG LIVC++RATRLVKSQQ AGKEYV V R H   P 
Sbjct: 124 VAWIKRLLRVEKTGHSGTLDPKVTGNLIVCVDRATRLVKSQQGAGKEYVCVARFHAAVP- 182

Query: 149 LDEATVRRAIETLTGPLYQRPPLISAVKRQLRIRTIYESKLLEYDPKRRLVLFWVSCEAG 208
            D A V RA+E LTG ++QRPPLISAVKRQLR+RTIYESKLLE+D  R L +FW+SCEAG
Sbjct: 183 -DTARVARALEALTGAVFQRPPLISAVKRQLRVRTIYESKLLEHDADRHLAVFWISCEAG 241

Query: 209 TYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLR 268
           TY+RTLCVHLGLLLGVG HMQELRRVRSG+  E D MVTMHDV+DA+W  D   DESYLR
Sbjct: 242 TYVRTLCVHLGLLLGVGAHMQELRRVRSGILGETDNMVTMHDVMDARWAMDNFNDESYLR 301

Query: 269 RVIKPLESLLVHHKRIVIKDSCVNAVCYGAKLMLPGVLRYENDIECGEEVVIMTTKGEAV 328
           R++ PLE LL  +KR+V+KDS VNA+CYGAKLM+PG+LR+EN+IE GEEVV+MTTKGEA+
Sbjct: 302 RIVMPLEVLLTSYKRLVVKDSAVNAICYGAKLMIPGLLRFENEIEVGEEVVLMTTKGEAI 361

Query: 329 ALAIAHMSTSEIASCDHGVVARIKRVVMERDLYPRRWGLGPVASRKKAMIQRGELDKHGR 388
           A+ IA M+T+ +A+CDHG VA+IKRVVM+RD YPR+WGLGPVA +KK M+  G LDKHG+
Sbjct: 362 AIGIAEMTTAVMATCDHGAVAKIKRVVMDRDTYPRKWGLGPVALKKKKMVAEGLLDKHGK 421

Query: 389 PNEHTPSDWRR 399
           PNE TPS+W R
Sbjct: 422 PNEKTPSEWLR 432

gb|EAA13199.3| ENSANGP00000017710 [Anopheles gambiae str. PEST]
ref|XP_318082.2| ENSANGP00000017710 [Anopheles gambiae str. PEST]
(443 aa)

Score: 575 bits (1481), Expect: 1.04729e-162
Length: 390, Idn/Pos/Gap = 272/325/3 (69%/83%/0%)

Query:   8 SLAEQQRSLSFQIPSDAGENGLSTDSWPLLLKNYDRLNVRTTHYTPIPDAGYSPLKRPIQ  67
           +L E Q+S  FQ+   +    L T  WPLLLKN+DRLNVRT HYTP+P  G SPL R I 
Sbjct:  11 NLGEIQKSGDFQLKPSSAIASLDTSKWPLLLKNFDRLNVRTNHYTPLP-FGSSPLNRKIN  69

Query:  68 EYIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVK 127
           +Y+ +G INLDKP+NPSSHEVVAWIKRIL+V KTGHSGTLDP+VTGCLIVCI RATRLVK
Sbjct:  70 DYVSAGFINLDKPSNPSSHEVVAWIKRILKVNKTGHSGTLDPKVTGCLIVCINRATRLVK 129

Query: 128 SQQSAGKEYVAVLRLHGMRPELDEATVRRAIETLTGPLYQRPPLISAVKRQLRIRTIYES 187
           SQQSAGKEYVAV +LH    ++  A V + +E L G L+QRPPLISAVKRQLR+RT+Y+S
Sbjct: 130 SQQSAGKEYVAVFKLHSAVEKI--AKVTQGLEKLRGALFQRPPLISAVKRQLRVRTVYDS 187

Query: 188 KLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVT 247
           KLL+Y+ +R + +FWVSCEAG+YIRT+CVHLGL+LGVGG M ELRRVRSG+ SE DGMVT
Sbjct: 188 KLLDYNDQRNIGVFWVSCEAGSYIRTMCVHLGLVLGVGGQMLELRRVRSGIQSEKDGMVT 247

Query: 248 MHDVLDAQWLFDTTKDESYLRRVIKPLESLLVHHKRIVIKDSCVNAVCYGAKLMLPGVLR 307
           MHDVLDAQ+L++  KDES LRRVIKPLE LLV HKRI++KDS VNAVCYGAK++LPGVLR
Sbjct: 248 MHDVLDAQYLYENHKDESMLRRVIKPLEGLLVGHKRIIMKDSSVNAVCYGAKILLPGVLR 307

Query: 308 YENDIECGEEVVIMTTKGEAVALAIAHMSTSEIASCDHGVVARIKRVVMERDLYPRRWGL 367
           YE+ IE  +E+VI+TTKGEA+AL IA M+T+ +A CDHGVVA+IKRV+MERD YPR+WGL
Sbjct: 308 YEDGIEIDQEIVIVTTKGEAIALGIALMTTATMAGCDHGVVAKIKRVIMERDTYPRKWGL 367

Query: 368 GPVASRKKAMIQRGELDKHGRPNEHTPSDW 397
           GP AS KK +I  G+LDK+G+PNE+TP DW
Sbjct: 368 GPKASMKKQLIASGKLDKYGKPNENTPKDW 397

gb|AAB94298.1| nucleolar protein AfCbf5p
sp|O43102|CBF5_ASPFU Centromere/microtubule binding protein CBF5 (Centromere-binding factor 5) (Small nucleolar RNP protein CBF5) (H/ACA snoRNP protein CBF5)
(487 aa)

Score: 574 bits (1480), Expect: 1.64341e-162
Length: 408, Idn/Pos/Gap = 284/333/7 (69%/81%/1%)

Query:  13 QRSLSFQIPSDAGENGLSTDSWPLLLKNYDRLNVRTTHYTPIPDAGYSPLKRPIQEYIRS  72
           +  + + I  +AG + +ST+ WPLLLKNYD+L VRT H+TPIP AG SPLKR ++ YI S
Sbjct:   7 KEEMDYTIKPEAGASNISTEDWPLLLKNYDKLMVRTGHFTPIP-AGCSPLKRDLKSYISS  65

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           GVINLDKP+NPSSHEVVAW+KRILR EKTGHSGTLDP+VTGCLIVCI+RATRLVKSQQ A
Sbjct:  66 GVINLDKPSNPSSHEVVAWMKRILRAEKTGHSGTLDPKVTGCLIVCIDRATRLVKSQQGA 125

Query: 133 GKEYVAVLRLHGMRPELDEATVRRAIETLTGPLYQRPPLISAVKRQLRIRTIYESKLLEY 192
           GKEYV V+RLH   P   EA  +RA+ETLTG L+QRPPLISAVKRQLRIRTI+ESKL E+
Sbjct: 126 GKEYVCVIRLHDKIPG-GEAQFKRALETLTGALFQRPPLISAVKRQLRIRTIHESKLYEF 184

Query: 193 DPKRRLVLFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVL 252
           D  R L +FWVSCEAGTYIRTLCVHLGLLLGVG HMQELRRVRSG   E +G+VT+HDVL
Sbjct: 185 DNDRHLGVFWVSCEAGTYIRTLCVHLGLLLGVGAHMQELRRVRSGAMDENNGLVTLHDVL 244

Query: 253 DAQWLFDTTKDESYLRRVIKPLESLLVHHKRIVIKDSCVNAVCYGAKLMLPGVLRYENDI 312
           DAQW++D  +DESYLRRVI+PLESLL  +KRIV+KDS VNAVCYGAKLM+PG+LR+E  I
Sbjct: 245 DAQWMYDNQRDESYLRRVIQPLESLLTTYKRIVVKDSAVNAVCYGAKLMIPGLLRFEAGI 304

Query: 313 ECGEEVVIMTTKGEAVALAIAHMSTSEIASCDHGVVARIKRVVMERDLYPRRWGLGPVAS 372
           E  EEVV+MTTKGEA+A+ IA MST E+++CDHGVVA++KR +MERDLYPRRWGLGPVA 
Sbjct: 305 EVNEEVVLMTTKGEAIAIGIAQMSTVELSTCDHGVVAKVKRCIMERDLYPRRWGLGPVAL 364

Query: 373 RKKAMIQRGELDKHGRPNEHTPSDWRR-----VQPELESAPSRMERQA 415
            KK +   G+LDK+GR NE TP+ W+        PE  SA +  E  A
Sbjct: 365 EKKKLKSAGKLDKYGRANEDTPAKWKTEYKDYSAPEEASAHAASESTA 412

ref|XP_479248.1| putative centromere/microtubule binding protein [Oryza sativa (japonica cultivar-group)]
dbj|BAC16386.1| putative centromere/microtubule binding protein [Oryza sativa (japonica cultivar-group)]
(600 aa)

Score: 572 bits (1475), Expect: 6.29727e-162
Length: 393, Idn/Pos/Gap = 275/328/4 (69%/83%/1%)

Query:   8 SLAEQQ-RSLSFQIPSDAGENGLSTDSWPLLLKNYDRLNVRTTHYTPIPDAGYSPLKRPI  66
           SLAE + ++  + I   +    L T +WPLLLKNYDRLNVRT HYTP+P +G+SPLKRPI
Sbjct:  39 SLAEAEAKTDGYLIKPQSLVPSLDTSTWPLLLKNYDRLNVRTGHYTPLP-SGHSPLKRPI  97

Query:  67 QEYIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLV 126
            EY+R GVINLDKP+NPSSHEVVAWIKR+LRV+KTGHSGTLDP+VTG LIVC++RATRLV
Sbjct:  98 AEYLRYGVINLDKPSNPSSHEVVAWIKRLLRVDKTGHSGTLDPKVTGNLIVCVDRATRLV 157

Query: 127 KSQQSAGKEYVAVLRLHGMRPELDEATVRRAIETLTGPLYQRPPLISAVKRQLRIRTIYE 186
           KSQQ AGKEYV V R H   P  D A V RA+E LTG ++QRPPLISAVKRQLR+RTIYE
Sbjct: 158 KSQQGAGKEYVCVARFHAAVP--DTARVARALEALTGAVFQRPPLISAVKRQLRVRTIYE 215

Query: 187 SKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMV 246
           SKLLE+D  R L +FW+SCEAGTY+RTLCVHLGLLLGVG HMQELRRVRSG+  E D MV
Sbjct: 216 SKLLEHDADRHLAVFWISCEAGTYVRTLCVHLGLLLGVGAHMQELRRVRSGILGEQDNMV 275

Query: 247 TMHDVLDAQWLFDTTKDESYLRRVIKPLESLLVHHKRIVIKDSCVNAVCYGAKLMLPGVL 306
           TMHDV+DA+W  D   DE+YLRR++ PLE LL  +KR+V+KDS VNA+CYGAKLM+PG+L
Sbjct: 276 TMHDVMDARWAMDNYNDETYLRRIVMPLEVLLTSYKRLVVKDSAVNAICYGAKLMIPGLL 335

Query: 307 RYENDIECGEEVVIMTTKGEAVALAIAHMSTSEIASCDHGVVARIKRVVMERDLYPRRWG 366
           R+ENDI+ GEEVV+MTTKGEA+A+ IA M+T+ +A+CDHG VA+IKRVVM+RD YPR+WG
Sbjct: 336 RFENDIDVGEEVVLMTTKGEAIAIGIAEMTTAVMATCDHGAVAKIKRVVMDRDTYPRKWG 395

Query: 367 LGPVASRKKAMIQRGELDKHGRPNEHTPSDWRR 399
           LGPVA +KK M+  G LDKHG+PNE TP++W R
Sbjct: 396 LGPVALKKKKMVAEGLLDKHGKPNEKTPAEWIR 428

sp|Q9ESX5|DKC1_MOUSE Dyskerin (Nucleolar protein NAP57)
emb|CAC04528.1| DYSKERIN [Mus musculus]
(509 aa)

Score: 572 bits (1474), Expect: 6.73195e-162
Length: 398, Idn/Pos/Gap = 275/333/5 (69%/83%/1%)

Query:   3 PKSSASLAEQQRSLSFQIPSDAGENGLSTDSWPLLLKNYDRLNVRTTHYTPIPDAGYSPL  62
           P     +AE Q +  F I  ++    L T  WPLLLKN+D+LNVRT HYTP+P  G +PL
Sbjct:  21 PLQEDDVAEIQHAEEFLIKPESKVAQLDTSQWPLLLKNFDKLNVRTAHYTPLP-CGSNPL  79

Query:  63 KRPIQEYIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERA 122
           KR I +YIR+G INLDKP+NPSSHEVVAWI+RILRVEKTGHSGTLDP+VTGCLIVCIERA
Sbjct:  80 KREIGDYIRTGFINLDKPSNPSSHEVVAWIRRILRVEKTGHSGTLDPKVTGCLIVCIERA 139

Query: 123 TRLVKSQQSAGKEYVAVLRLHGMRPELDEAT-VRRAIETLTGPLYQRPPLISAVKRQLRI 181
           TRLVKSQQSAGKEYV ++RLH     ++  T + RA+ETLTG L+QRPPLI+AVKRQLR+
Sbjct: 140 TRLVKSQQSAGKEYVGIVRLHN---AIEGGTQLSRALETLTGALFQRPPLIAAVKRQLRV 196

Query: 182 RTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSE 241
           RTIYESK++EYDP+RRL +FWVSCEAGTYIRTLCVHL  +LG G  MQELRRVRSGV SE
Sbjct: 197 RTIYESKMIEYDPERRLGIFWVSCEAGTYIRTLCVHLCFVLGSGCQMQELRRVRSGVMSE 256

Query: 242 YDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPLESLLVHHKRIVIKDSCVNAVCYGAKLM 301
            D MVTMHDVLDAQWL+D  KDESYLRRV+ PLE LL  HKR+V+KDS VNA+CYGAK+M
Sbjct: 257 KDHMVTMHDVLDAQWLYDNHKDESYLRRVVYPLEKLLTSHKRLVMKDSAVNAICYGAKIM 316

Query: 302 LPGVLRYENDIECGEEVVIMTTKGEAVALAIAHMSTSEIASCDHGVVARIKRVVMERDLY 361
           LPG+LRYE+ IE  +E+V++TTKGEA+ +AIA M+T+ I++CDHG+VA+IKRV+MERD Y
Sbjct: 317 LPGLLRYEDGIEVNQEIVVITTKGEAICMAIALMTTAVISTCDHGIVAKIKRVIMERDTY 376

Query: 362 PRRWGLGPVASRKKAMIQRGELDKHGRPNEHTPSDWRR 399
           PR+WGLGP AS+KK MI++G LDKHG+P ++TP+ W++
Sbjct: 377 PRKWGLGPKASQKKMMIKQGLLDKHGKPTDNTPATWKQ 414

sp|P33322|CBF5_YEAST Centromere/microtubule binding protein CBF5 (Centromere-binding factor 5) (Small nucleolar RNP protein CBF5) (H/ACA snoRNP protein CBF5) (p64')
gb|AAB67463.1| Cbf5p: centromere/microtubule binding protein [Saccharomyces cerevisiae]
ref|NP_013276.1| Cbf5p [Saccharomyces cerevisiae]
gb|AAA34473.1| centromere/microtubule binding protein
(483 aa)

Score: 571 bits (1471), Expect: 1.89441e-161
Length: 390, Idn/Pos/Gap = 274/325/3 (70%/83%/0%)

Query:  18 FQIPSDAGENGLSTDSWPLLLKNYDRLNVRTTHYTPIPDAGYSPLKRPIQEYIRSGVINL  77
           F I  +A      T  WPLLLKN+D+L VR+ HYTPIP AG SPLKR ++ YI SGVINL
Sbjct:   6 FVIKPEAAGASTDTSEWPLLLKNFDKLLVRSGHYTPIP-AGSSPLKRDLKSYISSGVINL  64

Query:  78 DKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAGKEYV 137
           DKP+NPSSHEVVAWIKRILR EKTGHSGTLDP+VTGCLIVCI+RATRLVKSQQ AGKEYV
Sbjct:  65 DKPSNPSSHEVVAWIKRILRCEKTGHSGTLDPKVTGCLIVCIDRATRLVKSQQGAGKEYV 124

Query: 138 AVLRLHGMRPELDEATVRRAIETLTGPLYQRPPLISAVKRQLRIRTIYESKLLEYDPKRR 197
            ++RLH      DE  + R++E LTG L+QRPPLISAVKRQLR+RTIYES L+E+D KR 
Sbjct: 125 CIVRLHDALK--DEKDLGRSLENLTGALFQRPPLISAVKRQLRVRTIYESNLIEFDNKRN 182

Query: 198 LVLFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWL 257
           L +FW SCEAGTY+RTLCVHLG+LLGVGGHMQELRRVRSG  SE D MVT+HDV+DAQW+
Sbjct: 183 LGVFWASCEAGTYMRTLCVHLGMLLGVGGHMQELRRVRSGALSENDNMVTLHDVMDAQWV 242

Query: 258 FDTTKDESYLRRVIKPLESLLVHHKRIVIKDSCVNAVCYGAKLMLPGVLRYENDIECGEE 317
           +D T+DESYLR +I+PLE+LLV +KRIV+KDS VNAVCYGAKLM+PG+LRYE  IE  +E
Sbjct: 243 YDNTRDESYLRSIIQPLETLLVGYKRIVVKDSAVNAVCYGAKLMIPGLLRYEEGIELYDE 302

Query: 318 VVIMTTKGEAVALAIAHMSTSEIASCDHGVVARIKRVVMERDLYPRRWGLGPVASRKKAM 377
           +V++TTKGEA+A+AIA MST ++ASCDHGVVA +KR +MERDLYPRRWGLGPVA +KK M
Sbjct: 303 IVLITTKGEAIAVAIAQMSTVDLASCDHGVVASVKRCIMERDLYPRRWGLGPVAQKKKQM 362

Query: 378 IQRGELDKHGRPNEHTPSDWRRVQPELESA 407
              G+LDK+GR NE+TP  W++    L++A
Sbjct: 363 KADGKLDKYGRVNENTPEQWKKEYVPLDNA 392

emb|CAG79496.1| unnamed protein product [Yarrowia lipolytica CLIB99]
ref|XP_503903.1| hypothetical protein [Yarrowia lipolytica]
(485 aa)

Score: 568 bits (1464), Expect: 1.16796e-160
Length: 379, Idn/Pos/Gap = 274/320/4 (72%/84%/1%)

Query:  21 PSDAGENGLSTDSWPLLLKNYDRLNVRTTHYTPIPDAGYSPLKRPIQEYIRSGVINLDKP  80
           P + G +   T  WPLLLKNYD+L VR+ HYTPIP  G SPLKR ++ YI SGVINLDKP
Sbjct:  15 PENVGPSA-DTSEWPLLLKNYDKLLVRSGHYTPIP-TGCSPLKRDLKSYIASGVINLDKP  72

Query:  81 ANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAGKEYVAVL 140
           +NPSSHEVVAWIKRILR EKTGHSGTLDP+VTGCLIVCI+RATRLVKSQQ AGKEYV ++
Sbjct:  73 SNPSSHEVVAWIKRILRCEKTGHSGTLDPKVTGCLIVCIDRATRLVKSQQGAGKEYVCIV 132

Query: 141 RLHGMRPELDEATVRRAIETLTGPLYQRPPLISAVKRQLRIRTIYESKLLEYDPKRRLVL 200
           RLH      DE  + R +E LTG L+QRPPLISAVKRQLR+RTIY+SKLLE+D  R L +
Sbjct: 133 RLHDALE--DEKEMARGLENLTGALFQRPPLISAVKRQLRVRTIYDSKLLEFDNDRHLGV 190

Query: 201 FWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDT 260
           FW SCEAGTY+RTLCVHLG+LLGVGGHMQELRRVRSG   E DGMVT+HD+LDAQWL+D 
Sbjct: 191 FWASCEAGTYMRTLCVHLGMLLGVGGHMQELRRVRSGALDESDGMVTLHDILDAQWLYDN 250

Query: 261 TKDESYLRRVIKPLESLLVHHKRIVIKDSCVNAVCYGAKLMLPGVLRYENDIECGEEVVI 320
           TKDESYLRR I+PLESLL+ +KRIV+KDS VN++CYGAKLMLPGVLRYE  IE  +E+V+
Sbjct: 251 TKDESYLRRCIRPLESLLLGYKRIVVKDSAVNSICYGAKLMLPGVLRYEEGIELEDEIVL 310

Query: 321 MTTKGEAVALAIAHMSTSEIASCDHGVVARIKRVVMERDLYPRRWGLGPVASRKKAMIQR 380
           +TTKGEA+AL IA M+T ++ASCDHGVV+RIKR +MERD YPRRWGLGPVA+ KK +   
Sbjct: 311 ITTKGEAIALGIAQMTTVDLASCDHGVVSRIKRCIMERDTYPRRWGLGPVATEKKKLKAD 370

Query: 381 GELDKHGRPNEHTPSDWRR 399
           G+LDK+GRPNE TP+DW++
Sbjct: 371 GKLDKYGRPNESTPADWKK 389

ref|NP_525120.1| CG3333-PA, isoform A [Drosophila melanogaster]
ref|NP_001014547.1| CG3333-PB, isoform B [Drosophila melanogaster]
gb|AAX52682.1| CG3333-PB, isoform B [Drosophila melanogaster]
gb|AAF47178.1| CG3333-PA, isoform A [Drosophila melanogaster]
sp|O44081|NOP60_DROME Nucleolar protein AT band 60B (Minifly protein)
gb|AAD16092.1| minifly protein [Drosophila melanogaster]
gb|AAC97117.1| nucleolar protein at band 60B [Drosophila melanogaster]
(508 aa)

Score: 567 bits (1460), Expect: 3.5727e-160
Length: 395, Idn/Pos/Gap = 272/326/3 (68%/82%/0%)

Query:   3 PKSSASLAEQQRSLSFQIPSDAGENGLSTDSWPLLLKNYDRLNVRTTHYTPIPDAGYSPL  62
           P     +   Q+  +FQI   +    L T  WPLLLKN+D+LN+R+ HYTP+   G SPL
Sbjct:  19 PLDGDDIGTLQKQGNFQIKPSSKIAELDTSQWPLLLKNFDKLNIRSNHYTPLAH-GSSPL  77

Query:  63 KRPIQEYIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERA 122
            R I+EY+++G INLDKP+NPSSHEVVAWIK+IL+VEKTGHSGTLDP+VTGCLIVCI+RA
Sbjct:  78 NRDIKEYMKTGFINLDKPSNPSSHEVVAWIKKILKVEKTGHSGTLDPKVTGCLIVCIDRA 137

Query: 123 TRLVKSQQSAGKEYVAVLRLHGMRPELDEATVRRAIETLTGPLYQRPPLISAVKRQLRIR 182
           TRLVKSQQSAGKEYVA+ +LHG    +  A VR+ +E L G L+QRPPLISAVKRQLR+R
Sbjct: 138 TRLVKSQQSAGKEYVAIFKLHGAVESV--AKVRQGLEKLRGALFQRPPLISAVKRQLRVR 195

Query: 183 TIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEY 242
           T+Y+SKLL+YD  R + +FWVSCEAG+YIRT+CVHLGL+LGVGG M ELRRVRSG+ SE 
Sbjct: 196 TVYDSKLLDYDETRNMGVFWVSCEAGSYIRTMCVHLGLVLGVGGQMLELRRVRSGIQSER 255

Query: 243 DGMVTMHDVLDAQWLFDTTKDESYLRRVIKPLESLLVHHKRIVIKDSCVNAVCYGAKLML 302
           DGMVTMHDVLDA WL++  KDES LRRVIKPLE LLV+HKRI++KDS VNAVCYGAK+ L
Sbjct: 256 DGMVTMHDVLDAMWLYENHKDESMLRRVIKPLEGLLVNHKRIIMKDSSVNAVCYGAKITL 315

Query: 303 PGVLRYENDIECGEEVVIMTTKGEAVALAIAHMSTSEIASCDHGVVARIKRVVMERDLYP 362
           PGVLRYE+ IE  +E+VI TTKGEA+ LAIA M+T+ +ASCDHGVVA+IKRV+MERD YP
Sbjct: 316 PGVLRYEDGIEIDQEIVICTTKGEAICLAIALMTTATMASCDHGVVAKIKRVIMERDTYP 375

Query: 363 RRWGLGPVASRKKAMIQRGELDKHGRPNEHTPSDW 397
           R+WGLGP AS KKA+I  G+LDK GRPNE+TP +W
Sbjct: 376 RKWGLGPKASAKKALIAAGKLDKFGRPNENTPKEW 410

gb|AAL23694.1| rRNA pseudouridine synthase [Emericella nidulans]
gb|AAB94296.1| nucleolar protein AnCbf5p
sp|O43100|CBF5_EMENI Centromere/microtubule binding protein CBF5 (Centromere-binding factor 5) (Small nucleolar RNP protein CBF5) (H/ACA snoRNP protein CBF5)
(481 aa)

Score: 566 bits (1459), Expect: 3.94893e-160
Length: 402, Idn/Pos/Gap = 282/333/2 (70%/82%/0%)

Query:  14 RSLSFQIPSDAGENGLSTDSWPLLLKNYDRLNVRTTHYTPIPDAGYSPLKRPIQEYIRSG  73
           + + + I  +A  + ++T+ WPLLLKNYD+L VRT H+TPIP AG SPLKR ++ YI SG
Sbjct:   3 KEVDYTIKPEATASNINTEDWPLLLKNYDKLMVRTGHFTPIP-AGSSPLKRDLKSYINSG  61

Query:  74 VINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAG 133
           VINLDKP+NPSSHEVVAW+KRILR EKTGHSGTLDP+VTGCLIVCI+RATRLVKSQQ AG
Sbjct:  62 VINLDKPSNPSSHEVVAWMKRILRAEKTGHSGTLDPKVTGCLIVCIDRATRLVKSQQGAG 121

Query: 134 KEYVAVLRLHGMRPELDEATVRRAIETLTGPLYQRPPLISAVKRQLRIRTIYESKLLEYD 193
           KEYV V+RLH   P   EA  +RA+ETLTG L+QRPPLISAVKRQLRIRTI+ESKL E+D
Sbjct: 122 KEYVCVIRLHDKIPG-GEAQFKRALETLTGALFQRPPLISAVKRQLRIRTIHESKLYEFD 180

Query: 194 PKRRLVLFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLD 253
            +R L +FWVSCEAGTYIRTLCVHLGLLLGVG HMQELRRVRSG  SE +GMVT+HDVLD
Sbjct: 181 NERHLGVFWVSCEAGTYIRTLCVHLGLLLGVGAHMQELRRVRSGAMSENEGMVTLHDVLD 240

Query: 254 AQWLFDTTKDESYLRRVIKPLESLLVHHKRIVIKDSCVNAVCYGAKLMLPGVLRYENDIE 313
           AQWL+D  +DESYLR+VIKPLESLL  +KRIV+KDS VNAVCYGAKLM+PG+LR+E  IE
Sbjct: 241 AQWLYDNQRDESYLRKVIKPLESLLTTYKRIVVKDSAVNAVCYGAKLMIPGLLRFEAGIE 300

Query: 314 CGEEVVIMTTKGEAVALAIAHMSTSEIASCDHGVVARIKRVVMERDLYPRRWGLGPVASR 373
            GEEVV+MTTKGEA+A+ IA MST E+++CDHGVVA++KR +MERDLYPRRWGLGPVA  
Sbjct: 301 LGEEVVLMTTKGEAIAIGIAQMSTVELSTCDHGVVAKVKRCIMERDLYPRRWGLGPVALE 360

Query: 374 KKAMIQRGELDKHGRPNEHTPSDWRRVQPELESAPSRMERQA 415
           KK +   G+LDK+GR NE TP+ W+    +  +      +QA
Sbjct: 361 KKKLKSSGKLDKYGRANEATPAKWKSEYKDYSAPDGDSSQQA 402

gb|AAL90146.1| AT23018p [Drosophila melanogaster]
(468 aa)

Score: 566 bits (1458), Expect: 5.20068e-160
Length: 395, Idn/Pos/Gap = 272/326/3 (68%/82%/0%)

Query:   3 PKSSASLAEQQRSLSFQIPSDAGENGLSTDSWPLLLKNYDRLNVRTTHYTPIPDAGYSPL  62
           P     +   Q+  +FQI   +    L T  WPLLLKN+D+LN+R+ HYTP+   G SPL
Sbjct:  19 PLDGDDIGTLQKQGNFQIKPSSKIAELDTSQWPLLLKNFDKLNIRSNHYTPLAH-GSSPL  77

Query:  63 KRPIQEYIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERA 122
            R I+EY+++G INLDKP+NPSSHEVVAWIK+IL+VEKTGHSGTLDP+VTGCLIVCI+RA
Sbjct:  78 NRDIKEYMKTGFINLDKPSNPSSHEVVAWIKKILKVEKTGHSGTLDPKVTGCLIVCIDRA 137

Query: 123 TRLVKSQQSAGKEYVAVLRLHGMRPELDEATVRRAIETLTGPLYQRPPLISAVKRQLRIR 182
           TRLVKSQQSAGKEYVA+ +LHG    +  A VR+ +E L G L+QRPPLISAVKRQLR+R
Sbjct: 138 TRLVKSQQSAGKEYVAIFKLHGAVESV--AKVRQGLEKLRGALFQRPPLISAVKRQLRVR 195

Query: 183 TIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEY 242
           T+Y+SKLL+YD  R + +FWVSCEAG+YIRT+CVHLGL+LGVGG M ELRRVRSG+ SE 
Sbjct: 196 TVYDSKLLDYDETRNMGVFWVSCEAGSYIRTMCVHLGLVLGVGGQMLELRRVRSGIQSER 255

Query: 243 DGMVTMHDVLDAQWLFDTTKDESYLRRVIKPLESLLVHHKRIVIKDSCVNAVCYGAKLML 302
           DGMVTMHDVLDA WL++  KDES LRRVIKPLE LLV+HKRI++KDS VNAVCYGAK+ L
Sbjct: 256 DGMVTMHDVLDAMWLYENHKDESMLRRVIKPLEGLLVNHKRIIMKDSSVNAVCYGAKITL 315

Query: 303 PGVLRYENDIECGEEVVIMTTKGEAVALAIAHMSTSEIASCDHGVVARIKRVVMERDLYP 362
           PGVLRYE+ IE  +E+VI TTKGEA+ LAIA M+T+ +ASCDHGVVA+IKRV+MERD YP
Sbjct: 316 PGVLRYEDGIEIDQEIVICTTKGEAICLAIALMTTATMASCDHGVVAKIKRVIMERDTYP 375

Query: 363 RRWGLGPVASRKKAMIQRGELDKHGRPNEHTPSDW 397
           R+WGLGP AS KKA+I  G+LDK GRPNE+TP +W
Sbjct: 376 RKWGLGPKASAKKALIAAGKLDKFGRPNENTPKEW 410

gb|AAH47840.1| Dkc1 protein [Danio rerio]
(497 aa)

Score: 564 bits (1453), Expect: 2.07771e-159
Length: 394, Idn/Pos/Gap = 281/330/3 (71%/83%/0%)

Query:   5 SSASLAEQQRSLSFQIPSDAGENGLSTDSWPLLLKNYDRLNVRTTHYTPIPDAGYSPLKR  64
           S   + + Q S  F I  ++    L T  WPLLLKN+D+LN+RT HYTP+P  G +PLKR
Sbjct:  18 SDEEVGDIQESGDFLIKPESKVASLDTSQWPLLLKNFDKLNIRTAHYTPLPH-GSNPLKR  76

Query:  65 PIQEYIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATR 124
            I +Y+RSG INLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDP+VTGCLIV +ERATR
Sbjct:  77 GIHDYVRSGFINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPKVTGCLIVYVERATR 136

Query: 125 LVKSQQSAGKEYVAVLRLHGMRPELDEATVRRAIETLTGPLYQRPPLISAVKRQLRIRTI 184
           LVKSQQSAGKEYV ++RLH      +E  + RA+E LTG L+QRPPLI+AVKRQLR+RTI
Sbjct: 137 LVKSQQSAGKEYVGIVRLHNALE--NEHQLARALECLTGALFQRPPLIAAVKRQLRVRTI 194

Query: 185 YESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDG 244
           YESKL+EYDP+RRL +FWVSCEAGTYIRTLCVHLGLLLGVGG MQELRRVRSGV  E D 
Sbjct: 195 YESKLIEYDPERRLGIFWVSCEAGTYIRTLCVHLGLLLGVGGQMQELRRVRSGVLGEKDN 254

Query: 245 MVTMHDVLDAQWLFDTTKDESYLRRVIKPLESLLVHHKRIVIKDSCVNAVCYGAKLMLPG 304
           +VTMHDVLDAQW FD  KDE+YLRRVI PLE LL+ HKRIV+KDS VNA+CYGAK+MLPG
Sbjct: 255 LVTMHDVLDAQWQFDHNKDETYLRRVIFPLEKLLISHKRIVMKDSAVNAICYGAKIMLPG 314

Query: 305 VLRYENDIECGEEVVIMTTKGEAVALAIAHMSTSEIASCDHGVVARIKRVVMERDLYPRR 364
           VLRYE+ IE  +++V++TTKGEA+  A+A M+T+ I++CDHGVVA+IKRV+MERD YPR+
Sbjct: 315 VLRYEDGIEVNQDIVVITTKGEAICTAVALMTTAVISTCDHGVVAKIKRVIMERDTYPRK 374

Query: 365 WGLGPVASRKKAMIQRGELDKHGRPNEHTPSDWR 398
           WGLGP AS+KK MIQ+G LDKHG+PN  TPSDW+
Sbjct: 375 WGLGPKASQKKMMIQKGLLDKHGKPNNSTPSDWK 408

gb|AAS50359.1| AAL007Cp [Ashbya gossypii ATCC 10895]
ref|NP_982535.1| AAL007Cp [Eremothecium gossypii]
(485 aa)

Score: 563 bits (1450), Expect: 5.03143e-159
Length: 369, Idn/Pos/Gap = 269/319/3 (72%/86%/0%)

Query:  31 TDSWPLLLKNYDRLNVRTTHYTPIPDAGYSPLKRPIQEYIRSGVINLDKPANPSSHEVVA  90
           T  WPLLLKNYD+L VR+ HYTPIP AG SPLKR ++ Y+ SGVINLDKP+NPSSHEVVA
Sbjct:  18 TSEWPLLLKNYDKLLVRSGHYTPIP-AGASPLKRDLKSYVSSGVINLDKPSNPSSHEVVA  76

Query:  91 WIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAGKEYVAVLRLHGMRPELD 150
           WIKRILR EKTGHSGTLDP+VTGCLIVCI+RATRLVKSQQ AGKEYV ++RLH      D
Sbjct:  77 WIKRILRCEKTGHSGTLDPKVTGCLIVCIDRATRLVKSQQGAGKEYVCIVRLHDALK--D 134

Query: 151 EATVRRAIETLTGPLYQRPPLISAVKRQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTY 210
           E  + R +E LTG L+QRPPLISAVKRQLR+RTIY+SKL+E+D KR L +FW SCEAGTY
Sbjct: 135 EKDLGRELENLTGALFQRPPLISAVKRQLRVRTIYDSKLIEFDNKRNLGVFWASCEAGTY 194

Query: 211 IRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRV 270
           +RTLCVHLG+LLGVGGHMQELRRVRSG   E D MVT+HDVLDAQW++D T+DESYLR++
Sbjct: 195 MRTLCVHLGMLLGVGGHMQELRRVRSGALDENDNMVTLHDVLDAQWVYDNTRDESYLRKI 254

Query: 271 IKPLESLLVHHKRIVIKDSCVNAVCYGAKLMLPGVLRYENDIECGEEVVIMTTKGEAVAL 330
           I+PLE+LLV +KRIV+KDS VNAVCYGAKLM+PG+LRYE  IE  +EVV++TTKGEA+A+
Sbjct: 255 IQPLETLLVGYKRIVVKDSAVNAVCYGAKLMIPGLLRYEEGIELYDEVVLITTKGEAIAV 314

Query: 331 AIAHMSTSEIASCDHGVVARIKRVVMERDLYPRRWGLGPVASRKKAMIQRGELDKHGRPN 390
           AIA MST ++A+CDHGVVA++KR +MERDLYPRRWGLGPVA +KK +   G+LDK+GR N
Sbjct: 315 AIAQMSTVDLATCDHGVVAKVKRCIMERDLYPRRWGLGPVAQKKKQLKADGKLDKYGRVN 374

Query: 391 EHTPSDWRR 399
           E+TP DW++
Sbjct: 375 ENTPEDWKK 383

gb|AAD19897.1| minifly protein [Drosophila melanogaster]
(508 aa)

Score: 563 bits (1450), Expect: 5.07359e-159
Length: 395, Idn/Pos/Gap = 271/325/3 (68%/82%/0%)

Query:   3 PKSSASLAEQQRSLSFQIPSDAGENGLSTDSWPLLLKNYDRLNVRTTHYTPIPDAGYSPL  62
           P     +   Q+  +FQI   +    L T  WPLLLKN+D+LN+R+ HYT +   G SPL
Sbjct:  19 PLDGDDIGTLQKQGNFQIKPSSKIAELDTSQWPLLLKNFDKLNIRSNHYTRLAH-GSSPL  77

Query:  63 KRPIQEYIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERA 122
            R I+EY+++G INLDKP+NPSSHEVVAWIK+IL+VEKTGHSGTLDP+VTGCLIVCI+RA
Sbjct:  78 NRDIKEYMKTGFINLDKPSNPSSHEVVAWIKKILKVEKTGHSGTLDPKVTGCLIVCIDRA 137

Query: 123 TRLVKSQQSAGKEYVAVLRLHGMRPELDEATVRRAIETLTGPLYQRPPLISAVKRQLRIR 182
           TRLVKSQQSAGKEYVA+ +LHG    +  A VR+ +E L G L+QRPPLISAVKRQLR+R
Sbjct: 138 TRLVKSQQSAGKEYVAIFKLHGAVESV--AKVRQGLEKLRGALFQRPPLISAVKRQLRVR 195

Query: 183 TIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEY 242
           T+Y+SKLL+YD  R + +FWVSCEAG+YIRT+CVHLGL+LGVGG M ELRRVRSG+ SE 
Sbjct: 196 TVYDSKLLDYDETRNMGVFWVSCEAGSYIRTMCVHLGLVLGVGGQMLELRRVRSGIQSER 255

Query: 243 DGMVTMHDVLDAQWLFDTTKDESYLRRVIKPLESLLVHHKRIVIKDSCVNAVCYGAKLML 302
           DGMVTMHDVLDA WL++  KDES LRRVIKPLE LLV+HKRI++KDS VNAVCYGAK+ L
Sbjct: 256 DGMVTMHDVLDAMWLYENHKDESMLRRVIKPLEGLLVNHKRIIMKDSSVNAVCYGAKITL 315

Query: 303 PGVLRYENDIECGEEVVIMTTKGEAVALAIAHMSTSEIASCDHGVVARIKRVVMERDLYP 362
           PGVLRYE+ IE  +E+VI TTKGEA+ LAIA M+T+ +ASCDHGVVA+IKRV+MERD YP
Sbjct: 316 PGVLRYEDGIEIDQEIVICTTKGEAICLAIALMTTATMASCDHGVVAKIKRVIMERDTYP 375

Query: 363 RRWGLGPVASRKKAMIQRGELDKHGRPNEHTPSDW 397
           R+WGLGP AS KKA+I  G+LDK GRPNE+TP +W
Sbjct: 376 RKWGLGPKASAKKALIAAGKLDKFGRPNENTPKEW 410

ref|XP_489850.1| similar to DYSKERIN [Mus musculus]
ref|XP_289923.1| similar to DYSKERIN [Mus musculus]
(509 aa)

Score: 561 bits (1447), Expect: 1.13975e-158
Length: 398, Idn/Pos/Gap = 280/337/5 (70%/84%/1%)

Query:   3 PKSSASLAEQQRSLSFQIPSDAGENGLSTDSWPLLLKNYDRLNVRTTHYTPIPDAGYSPL  62
           P     +AE Q +  F I  ++    L T  WPLLLKN+D+LNVRT HYTP+P  G +PL
Sbjct:  21 PLQEDDVAEIQHAEEFLIKPESKVAQLDTSQWPLLLKNFDKLNVRTAHYTPLP-CGSNPL  79

Query:  63 KRPIQEYIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERA 122
           KR I +YIR+G INLDKP+NPSSHEVVAWI+RILRVEKTGHSGTLDP+VTGCLIVCIERA
Sbjct:  80 KREIGDYIRTGFINLDKPSNPSSHEVVAWIRRILRVEKTGHSGTLDPKVTGCLIVCIERA 139

Query: 123 TRLVKSQQSAGKEYVAVLRLHGMRPELDEAT-VRRAIETLTGPLYQRPPLISAVKRQLRI 181
           TRLVKSQQSAGKEYV ++RLH     ++  T + RA+ETLTG L+QRPPLI+AVKRQLR+
Sbjct: 140 TRLVKSQQSAGKEYVGIVRLHN---AIEGGTQLSRALETLTGALFQRPPLIAAVKRQLRV 196

Query: 182 RTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSE 241
           RTIYESK++EYDP+RRL +FWVSCEAGTYIRTLCVHLGLLLGVGG MQELRRVRSGV SE
Sbjct: 197 RTIYESKMIEYDPERRLGIFWVSCEAGTYIRTLCVHLGLLLGVGGQMQELRRVRSGVMSE 256

Query: 242 YDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPLESLLVHHKRIVIKDSCVNAVCYGAKLM 301
            D MVTMHDVLDAQWL+D  KDESYLRRV+ PLE LL  HKR+V+KDS VNA+CYGAK+M
Sbjct: 257 KDHMVTMHDVLDAQWLYDNHKDESYLRRVVYPLEKLLTSHKRLVMKDSAVNAICYGAKIM 316

Query: 302 LPGVLRYENDIECGEEVVIMTTKGEAVALAIAHMSTSEIASCDHGVVARIKRVVMERDLY 361
           LPG+LRYE+ IE  +E+V++TTKGEA+ +AIA M+T+ I++CDHG+VA+IKRV+MERD Y
Sbjct: 317 LPGLLRYEDGIEVNQEIVVITTKGEAICMAIALMTTAVISTCDHGIVAKIKRVIMERDTY 376

Query: 362 PRRWGLGPVASRKKAMIQRGELDKHGRPNEHTPSDWRR 399
           PR+WGLGP AS+KK MI++G LDKHG+P ++TP+ W++
Sbjct: 377 PRKWGLGPKASQKKMMIKQGLLDKHGKPTDNTPATWKQ 414

emb|CAG32114.1| hypothetical protein [Gallus gallus]
(516 aa)

Score: 561 bits (1446), Expect: 1.38087e-158
Length: 391, Idn/Pos/Gap = 284/333/3 (72%/85%/0%)

Query:   9 LAEQQRSLSFQIPSDAGENGLSTDSWPLLLKNYDRLNVRTTHYTPIPDAGYSPLKRPIQE  68
           +A+ Q +  F I  ++    L T  WPLLLKN+D+LNV TTHYTP+P +G +PLKR I +
Sbjct:  25 VADIQHTEEFLIKPESRVAQLDTSQWPLLLKNFDKLNVLTTHYTPLP-SGANPLKREISD  83

Query:  69 YIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKS 128
           Y+RSG INLDKP+NPSSHEVVAWI+RILRVEKTGHSGTLDP+VTGCLIVCIERATRLVKS
Sbjct:  84 YVRSGFINLDKPSNPSSHEVVAWIRRILRVEKTGHSGTLDPKVTGCLIVCIERATRLVKS 143

Query: 129 QQSAGKEYVAVLRLHGMRPELDEATVRRAIETLTGPLYQRPPLISAVKRQLRIRTIYESK 188
           QQSAGKEYV ++RLH       EA + RAIETLTG L+QRPPLI+AVKRQLR+RTIYESK
Sbjct: 144 QQSAGKEYVGIVRLHNAIES--EAQLARAIETLTGALFQRPPLIAAVKRQLRVRTIYESK 201

Query: 189 LLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTM 248
           L+EYDP+RRL +FWVSCEAGTYIRTLCVHLGLLLGVGG MQELRRVRSG+  E D MVTM
Sbjct: 202 LVEYDPERRLGIFWVSCEAGTYIRTLCVHLGLLLGVGGQMQELRRVRSGILGEMDNMVTM 261

Query: 249 HDVLDAQWLFDTTKDESYLRRVIKPLESLLVHHKRIVIKDSCVNAVCYGAKLMLPGVLRY 308
           HDVLDAQW +D  KD+SYLRRVI PLE LL  HKR+V+KDS VNA+CYGAK+MLPGVLRY
Sbjct: 262 HDVLDAQWQYDNNKDDSYLRRVILPLEKLLTSHKRLVMKDSAVNAICYGAKIMLPGVLRY 321

Query: 309 ENDIECGEEVVIMTTKGEAVALAIAHMSTSEIASCDHGVVARIKRVVMERDLYPRRWGLG 368
           E+ IE  +E+V++TTKGEA+ LAIA M+T+ I++CDHGVVA+IKRV+MERD YPR+WGLG
Sbjct: 322 EDGIELKQEIVVITTKGEAICLAIALMTTAVISTCDHGVVAKIKRVIMERDTYPRKWGLG 381

Query: 369 PVASRKKAMIQRGELDKHGRPNEHTPSDWRR 399
           P AS+KK MIQ+G LDKHG+PNE TP  W++
Sbjct: 382 PKASQKKMMIQKGLLDKHGKPNECTPDSWKK 412

gb|EAA60139.1| CBF5_EMENI Centromere/microtubule binding protein CBF5 (Centromere-binding factor 5) (Nucleolar protein CBF5) [Aspergillus nidulans FGSC A4]
ref|XP_412988.1| CBF5_EMENI Centromere/microtubule binding protein CBF5 (Centromere-binding factor 5) (Nucleolar protein CBF5) [Aspergillus nidulans FGSC A4]
(490 aa)

Score: 559 bits (1440), Expect: 6.73977e-158
Length: 411, Idn/Pos/Gap = 282/333/11 (68%/81%/2%)

Query:  14 RSLSFQIPSDAGENGLSTDSWPLLLKNYDRLNVRTTHYTPIPDAGYSPLKRPIQEYIRSG  73
           + + + I  +A  + ++T+ WPLLLKNYD+L VRT H+TPIP AG SPLKR ++ YI SG
Sbjct:   3 KEVDYTIKPEATASNINTEDWPLLLKNYDKLMVRTGHFTPIP-AGSSPLKRDLKSYINSG  61

Query:  74 VINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAG 133
           VINLDKP+NPSSHEVVAW+KRILR EKTGHSGTLDP+VTGCLIVCI+RATRLVKSQQ AG
Sbjct:  62 VINLDKPSNPSSHEVVAWMKRILRAEKTGHSGTLDPKVTGCLIVCIDRATRLVKSQQGAG 121

Query: 134 KEYVAVLRLHGMRPELDEATVRRAIETLTGPLYQRPPLISAVKRQLRIRTIYESKLLEYD 193
           KEYV V+RLH   P   EA  +RA+ETLTG L+QRPPLISAVKRQLRIRTI+ESKL E+D
Sbjct: 122 KEYVCVIRLHDKIPG-GEAQFKRALETLTGALFQRPPLISAVKRQLRIRTIHESKLYEFD 180

Query: 194 PKRRLVLFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLD 253
            +R L +FWVSCEAGTYIRTLCVHLGLLLGVG HMQELRRVRSG  SE +GMVT+HDVLD
Sbjct: 181 NERHLGVFWVSCEAGTYIRTLCVHLGLLLGVGAHMQELRRVRSGAMSENEGMVTLHDVLD 240

Query: 254 AQWLFDTTKDESYLRRVIKPLESLLVHHKRIVIKDSCVNAVCYGAKLMLPGVLRY----- 308
           AQWL+D  +DESYLR+VIKPLESLL  +KRIV+KDS VNAVCYGAKLM+PG+LR+     
Sbjct: 241 AQWLYDNQRDESYLRKVIKPLESLLTTYKRIVVKDSAVNAVCYGAKLMIPGLLRFGQKSL 300

Query: 309 ----ENDIECGEEVVIMTTKGEAVALAIAHMSTSEIASCDHGVVARIKRVVMERDLYPRR 364
               E  IE GEEVV+MTTKGEA+A+ IA MST E+++CDHGVVA++KR +MERDLYPRR
Sbjct: 301 TWGLEAGIELGEEVVLMTTKGEAIAIGIAQMSTVELSTCDHGVVAKVKRCIMERDLYPRR 360

Query: 365 WGLGPVASRKKAMIQRGELDKHGRPNEHTPSDWRRVQPELESAPSRMERQA 415
           WGLGPVA  KK +   G+LDK+GR NE TP+ W+    +  +      +QA
Sbjct: 361 WGLGPVALEKKKLKSSGKLDKYGRANEATPAKWKSEYKDYSAPDGDSSQQA 411

gb|EAK91507.1| likely snoRNP-associated pseudouridylate synthase [Candida albicans SC5314]
gb|EAK91469.1| likely snoRNP-associated pseudouridylate synthase [Candida albicans SC5314]
gb|AAB94297.1| nucleolar protein CaCbf5p
sp|O43101|CBF5_CANAL Centromere/microtubule binding protein CBF5 (Centromere-binding factor 5) (Small nucleolar RNP protein CBF5) (H/ACA snoRNP protein CBF5)
(479 aa)

Score: 558 bits (1438), Expect: 9.8109e-158
Length: 393, Idn/Pos/Gap = 268/327/10 (68%/83%/2%)

Query:  31 TDSWPLLLKNYDRLNVRTTHYTPIPDAGYSPLKRPIQEYIRSGVINLDKPANPSSHEVVA  90
           T  WPLLLKNYD+L VR+ HYTPIP AG +PL R I+ Y+ SGVINLDKP+NPSSHEVVA
Sbjct:  20 TSQWPLLLKNYDKLLVRSGHYTPIP-AGSAPLNRDIKSYVSSGVINLDKPSNPSSHEVVA  78

Query:  91 WIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAGKEYVAVLRLHGMRPELD 150
           WIKRILRVEKTGHSGTLDP+VTGCLIVCI+RATRLVKSQQ AGKEYV ++RLH      D
Sbjct:  79 WIKRILRVEKTGHSGTLDPKVTGCLIVCIDRATRLVKSQQGAGKEYVCIVRLHEQLK--D 136

Query: 151 EATVRRAIETLTGPLYQRPPLISAVKRQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTY 210
           +  + RA+E LTG L+QRPPLISAVKRQLR+RT+Y+SKL+E+D KR L +FW SCEAGTY
Sbjct: 137 DKELNRALENLTGALFQRPPLISAVKRQLRVRTVYDSKLIEFDNKRGLGVFWASCEAGTY 196

Query: 211 IRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRV 270
           +RTLCVHLG+LLGVGGHMQELRRVRSG  SE D +VT+HDVLDAQ+++D T+DESYLR++
Sbjct: 197 MRTLCVHLGMLLGVGGHMQELRRVRSGAMSESDNLVTLHDVLDAQYVYDNTRDESYLRKI 256

Query: 271 IKPLESLLVHHKRIVIKDSCVNAVCYGAKLMLPGVLRYENDIECGEEVVIMTTKGEAVAL 330
           I+PLESLLV +KR+V+KDS VN+VCYGAKLM+PG+LRYE  IE  +EVV+MTTKGEA+A+
Sbjct: 257 IQPLESLLVGYKRVVVKDSAVNSVCYGAKLMIPGLLRYEEGIELYDEVVLMTTKGEAIAI 316

Query: 331 AIAHMSTSEIASCDHGVVARIKRVVMERDLYPRRWGLGPVASRKKAMIQRGELDKHGRPN 390
            IA MST ++ SCDHG+VA++KR +MERD YPRRWGLGP+A +KK M   G+LDK+GR N
Sbjct: 317 GIAQMSTVDLQSCDHGIVAKVKRCIMERDTYPRRWGLGPIAQKKKQMKADGKLDKYGRVN 376

Query: 391 EHTPSDWRRVQPELESAPSRMERQAGPPVRPPK 423
           E+TP +W++   +L+  P+       PP+   K
Sbjct: 377 ENTPENWKKDYKDLDEQPA-------PPIPESK 402

ref|NP_596910.1| dyskeratosis congenita 1, dyskerin [Rattus norvegicus]
emb|CAA84402.1| NAP57 [Rattus norvegicus]
sp|P40615|DKC1_RAT Dyskerin (Nucleolar protein NAP57)
(509 aa)

Score: 556 bits (1434), Expect: 3.20824e-157
Length: 397, Idn/Pos/Gap = 285/334/3 (71%/84%/0%)

Query:   3 PKSSASLAEQQRSLSFQIPSDAGENGLSTDSWPLLLKNYDRLNVRTTHYTPIPDAGYSPL  62
           P   A +AE Q +  F I  ++    L T  WPLLLKN+DRLNVRTTHYTPIP  G +PL
Sbjct:  22 PLPEADVAEIQHAEDFLIKPESKAAQLDTSQWPLLLKNFDRLNVRTTHYTPIP-CGSNPL  80

Query:  63 KRPIQEYIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERA 122
           KR I EY+R+G INLDKP+NPSSHEVVAWI+RILRVEKTGHSGTLDP+VTGCLIVCIERA
Sbjct:  81 KREIGEYVRTGFINLDKPSNPSSHEVVAWIRRILRVEKTGHSGTLDPKVTGCLIVCIERA 140

Query: 123 TRLVKSQQSAGKEYVAVLRLHGMRPELDEATVRRAIETLTGPLYQRPPLISAVKRQLRIR 182
           TRLVKSQQSAGKEYV V+RLH        A + RA+ETLTG L+QRPPLI+AVKRQLR+R
Sbjct: 141 TRLVKSQQSAGKEYVGVVRLHNAIE--GTAQLSRALETLTGALFQRPPLIAAVKRQLRVR 198

Query: 183 TIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEY 242
           TIYES+++EYDP+RRL +FWVSCEAGTYIRTLCVHLGLLLGVGG MQELRRVRSGV  E 
Sbjct: 199 TIYESRVVEYDPERRLGVFWVSCEAGTYIRTLCVHLGLLLGVGGQMQELRRVRSGVVGER 258

Query: 243 DGMVTMHDVLDAQWLFDTTKDESYLRRVIKPLESLLVHHKRIVIKDSCVNAVCYGAKLML 302
           D MVTMHDVLDAQ+L+D  +DESYLRRV+ PLE LL  HKR+V+KDS VNA+CYGAK+ML
Sbjct: 259 DHMVTMHDVLDAQYLYDHHRDESYLRRVVFPLEKLLTSHKRLVMKDSAVNAICYGAKIML 318

Query: 303 PGVLRYENDIECGEEVVIMTTKGEAVALAIAHMSTSEIASCDHGVVARIKRVVMERDLYP 362
           PG+LRYE+ IE  +EVV++TTKGEAV +AIA M+T+ I++CDHGVVA+IKRV+MERD YP
Sbjct: 319 PGLLRYEDGIEVNQEVVVITTKGEAVCVAIALMTTAVISTCDHGVVAKIKRVIMERDTYP 378

Query: 363 RRWGLGPVASRKKAMIQRGELDKHGRPNEHTPSDWRR 399
           R+WGLGP AS+KK +I++G LDKHGRP + TP+ W R
Sbjct: 379 RKWGLGPKASQKKQLIKQGLLDKHGRPTDGTPASWTR 415

emb|CAB51168.1| dyskerin [Homo sapiens]
(524 aa)

Score: 555 bits (1430), Expect: 8.87873e-157
Length: 392, Idn/Pos/Gap = 280/335/5 (71%/85%/1%)

Query:   9 LAEQQRSLSFQIPSDAGENGLSTDSWPLLLKNYDRLNVRTTHYTPIPDAGYSPLKRPIQE  68
           +AE Q +  F I  ++    L T  WPLLLKN+D+LNVRTTHYTP+   G +PLKR I +
Sbjct:  27 VAEIQHAEEFLIKPESKVAKLDTSQWPLLLKNFDKLNVRTTHYTPLA-CGSNPLKREIGD  85

Query:  69 YIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKS 128
           YIR+G INLDKP+NPSSHEVVAWI+RILRVEKTGHSGTLDP+VTGCLIVCIERATRLVKS
Sbjct:  86 YIRTGFINLDKPSNPSSHEVVAWIRRILRVEKTGHSGTLDPKVTGCLIVCIERATRLVKS 145

Query: 129 QQSAGKEYVAVLRLHGMRPELDEAT-VRRAIETLTGPLYQRPPLISAVKRQLRIRTIYES 187
           QQSAGKEYV ++RLH     ++  T + RA+ETLTG L+QRPPLI+AVKRQLR+RTIYES
Sbjct: 146 QQSAGKEYVGIVRLHN---AIEGGTQLSRALETLTGALFQRPPLIAAVKRQLRVRTIYES 202

Query: 188 KLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVT 247
           K++EYDP+RRL +FWVSCEAGTYIRTLCVHLGLLLGVGG MQELRRVRSGV SE D MVT
Sbjct: 203 KMIEYDPERRLGIFWVSCEAGTYIRTLCVHLGLLLGVGGQMQELRRVRSGVMSEKDHMVT 262

Query: 248 MHDVLDAQWLFDTTKDESYLRRVIKPLESLLVHHKRIVIKDSCVNAVCYGAKLMLPGVLR 307
           MHDVLDAQWL+D  KDESYLRRV+ PLE LL  HKR+V+KDS VNA+CYGAK+MLPGVLR
Sbjct: 263 MHDVLDAQWLYDNHKDESYLRRVVYPLEKLLTSHKRLVMKDSAVNAICYGAKIMLPGVLR 322

Query: 308 YENDIECGEEVVIMTTKGEAVALAIAHMSTSEIASCDHGVVARIKRVVMERDLYPRRWGL 367
           YE+ IE  +E+V++TTKGEA+ +AIA M+T+ I++CDHG+VA+IKRV+MERD YPR+WGL
Sbjct: 323 YEDGIEVNQEIVVITTKGEAICMAIALMTTAVISTCDHGIVAKIKRVIMERDTYPRKWGL 382

Query: 368 GPVASRKKAMIQRGELDKHGRPNEHTPSDWRR 399
           GP AS+KK MI++G LDKHG+P + TP+ W++
Sbjct: 383 GPKASQKKLMIKQGLLDKHGKPTDSTPATWKQ 414

gb|AAB94299.1| Cbf5p homolog
(514 aa)

Score: 554 bits (1428), Expect: 1.5019e-156
Length: 392, Idn/Pos/Gap = 280/335/5 (71%/85%/1%)

Query:   9 LAEQQRSLSFQIPSDAGENGLSTDSWPLLLKNYDRLNVRTTHYTPIPDAGYSPLKRPIQE  68
           +AE Q +  F I  ++    L T  WPLLLKN+D+LNVRTTHYTP+   G +PLKR I +
Sbjct:  27 VAEIQHAEEFFIKPESKVAKLDTSQWPLLLKNFDKLNVRTTHYTPLA-CGSNPLKREIGD  85

Query:  69 YIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKS 128
           YIR+G INLDKP+NPSSHEVVAWI+RILRVEKTGHSGTLDP+VTGCLIVCIERATRLVKS
Sbjct:  86 YIRTGFINLDKPSNPSSHEVVAWIRRILRVEKTGHSGTLDPKVTGCLIVCIERATRLVKS 145

Query: 129 QQSAGKEYVAVLRLHGMRPELDEAT-VRRAIETLTGPLYQRPPLISAVKRQLRIRTIYES 187
           QQSAGKEYV ++RLH     ++  T + RA+ETLTG L+QRPPLI+AVKRQLR+RTIYES
Sbjct: 146 QQSAGKEYVGIVRLHN---AIEGGTQLSRALETLTGALFQRPPLIAAVKRQLRVRTIYES 202

Query: 188 KLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVT 247
           K++EYDP+RRL +FWVSCEAGTYIRTLCVHLGLLLGVGG MQELRRVRSGV SE D MVT
Sbjct: 203 KMIEYDPERRLGIFWVSCEAGTYIRTLCVHLGLLLGVGGQMQELRRVRSGVMSEKDHMVT 262

Query: 248 MHDVLDAQWLFDTTKDESYLRRVIKPLESLLVHHKRIVIKDSCVNAVCYGAKLMLPGVLR 307
           MHDVLDAQWL+D  KDESYLRRV+ PLE LL  HKR+V+KDS VNA+CYGAK+MLPGVLR
Sbjct: 263 MHDVLDAQWLYDNHKDESYLRRVVYPLEKLLTSHKRLVMKDSAVNAICYGAKIMLPGVLR 322

Query: 308 YENDIECGEEVVIMTTKGEAVALAIAHMSTSEIASCDHGVVARIKRVVMERDLYPRRWGL 367
           YE+ IE  +E+V++TTKGEA+ +AIA M+T+ I++CDHG+VA+IKRV+MERD YPR+WGL
Sbjct: 323 YEDGIEVNQEIVVITTKGEAICMAIALMTTAVISTCDHGIVAKIKRVIMERDTYPRKWGL 382

Query: 368 GPVASRKKAMIQRGELDKHGRPNEHTPSDWRR 399
           GP AS+KK MI++G LDKHG+P + TP+ W++
Sbjct: 383 GPKASQKKLMIKQGLLDKHGKPTDSTPATWKQ 414

emb|CAA11970.1| dyskerin [Homo sapiens]
gb|AAH10015.1| Dyskerin [Homo sapiens]
gb|AAD20232.1| dyskerin [Homo sapiens]
gb|AAD11815.1| dyskerin [Homo sapiens]
sp|O60832|DKC1_HUMAN Dyskerin (Nucleolar protein NAP57) (CBF5 homolog)
ref|NP_001354.1| dyskerin [Homo sapiens]
(514 aa)

Score: 554 bits (1427), Expect: 1.89715e-156
Length: 392, Idn/Pos/Gap = 280/335/5 (71%/85%/1%)

Query:   9 LAEQQRSLSFQIPSDAGENGLSTDSWPLLLKNYDRLNVRTTHYTPIPDAGYSPLKRPIQE  68
           +AE Q +  F I  ++    L T  WPLLLKN+D+LNVRTTHYTP+   G +PLKR I +
Sbjct:  27 VAEIQHAEEFLIKPESKVAKLDTSQWPLLLKNFDKLNVRTTHYTPLA-CGSNPLKREIGD  85

Query:  69 YIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKS 128
           YIR+G INLDKP+NPSSHEVVAWI+RILRVEKTGHSGTLDP+VTGCLIVCIERATRLVKS
Sbjct:  86 YIRTGFINLDKPSNPSSHEVVAWIRRILRVEKTGHSGTLDPKVTGCLIVCIERATRLVKS 145

Query: 129 QQSAGKEYVAVLRLHGMRPELDEAT-VRRAIETLTGPLYQRPPLISAVKRQLRIRTIYES 187
           QQSAGKEYV ++RLH     ++  T + RA+ETLTG L+QRPPLI+AVKRQLR+RTIYES
Sbjct: 146 QQSAGKEYVGIVRLHN---AIEGGTQLSRALETLTGALFQRPPLIAAVKRQLRVRTIYES 202

Query: 188 KLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVT 247
           K++EYDP+RRL +FWVSCEAGTYIRTLCVHLGLLLGVGG MQELRRVRSGV SE D MVT
Sbjct: 203 KMIEYDPERRLGIFWVSCEAGTYIRTLCVHLGLLLGVGGQMQELRRVRSGVMSEKDHMVT 262

Query: 248 MHDVLDAQWLFDTTKDESYLRRVIKPLESLLVHHKRIVIKDSCVNAVCYGAKLMLPGVLR 307
           MHDVLDAQWL+D  KDESYLRRV+ PLE LL  HKR+V+KDS VNA+CYGAK+MLPGVLR
Sbjct: 263 MHDVLDAQWLYDNHKDESYLRRVVYPLEKLLTSHKRLVMKDSAVNAICYGAKIMLPGVLR 322

Query: 308 YENDIECGEEVVIMTTKGEAVALAIAHMSTSEIASCDHGVVARIKRVVMERDLYPRRWGL 367
           YE+ IE  +E+V++TTKGEA+ +AIA M+T+ I++CDHG+VA+IKRV+MERD YPR+WGL
Sbjct: 323 YEDGIEVNQEIVVITTKGEAICMAIALMTTAVISTCDHGIVAKIKRVIMERDTYPRKWGL 382

Query: 368 GPVASRKKAMIQRGELDKHGRPNEHTPSDWRR 399
           GP AS+KK MI++G LDKHG+P + TP+ W++
Sbjct: 383 GPKASQKKLMIKQGLLDKHGKPTDSTPATWKQ 414

gb|EAL66526.1| hypothetical protein DDB0204297 [Dictyostelium discoideum]
(540 aa)

Score: 554 bits (1427), Expect: 1.97798e-156
Length: 369, Idn/Pos/Gap = 263/318/3 (71%/86%/0%)

Query:  29 LSTDSWPLLLKNYDRLNVRTTHYTPIPDAGYSPLKRPIQEYIRSGVINLDKPANPSSHEV  88
           L T  WPLLLKNYD+L+VRT HYTPIP+ G+SPLKRPI+EY++ G+INLDKP+NPSSHEV
Sbjct:  31 LDTSKWPLLLKNYDQLSVRTGHYTPIPN-GHSPLKRPIKEYVKYGIINLDKPSNPSSHEV  89

Query:  89 VAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAGKEYVAVLRLHGMRPE 148
           VAWI+ ILRV KTGHSGTLDP+VTGCLIVCIERATRLVKSQQ AGKEY+ ++RLHG    
Sbjct:  90 VAWIRTILRVTKTGHSGTLDPKVTGCLIVCIERATRLVKSQQGAGKEYIGIVRLHGAIEG 149

Query: 149 LDEATVRRAIETLTGPLYQRPPLISAVKRQLRIRTIYESKLLEYDPKRRLVLFWVSCEAG 208
             E  + +A++TLTG L+QRPP  SAVK++LR+RTI+ SKLLE+DP+R L L WV CEAG
Sbjct: 150 TTE--LSKAVDTLTGALFQRPPQKSAVKKRLRVRTIHNSKLLEFDPERNLGLIWVDCEAG 207

Query: 209 TYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLR 268
           TYIRTLCVH+GLL+GVGGHMQELRRVRSG+ SE  G VTMHDV DAQ+ +D +KDESYLR
Sbjct: 208 TYIRTLCVHIGLLMGVGGHMQELRRVRSGIMSEKKGQVTMHDVKDAQYEYDNSKDESYLR 267

Query: 269 RVIKPLESLLVHHKRIVIKDSCVNAVCYGAKLMLPGVLRYENDIECGEEVVIMTTKGEAV 328
           RVI+PLE++L ++KRIV+KDS +NA+CYGAKLM+PG+LRYE DIE  EEVV++TTKGEA+
Sbjct: 268 RVIQPLEAILTNYKRIVVKDSAINAICYGAKLMIPGLLRYEQDIESNEEVVLITTKGEAI 327

Query: 329 ALAIAHMSTSEIASCDHGVVARIKRVVMERDLYPRRWGLGPVASRKKAMIQRGELDKHGR 388
           A+ IA M+T+ +A+CDHGVVA IKRV+M+RD+YP RWGLGP A  KK MI+ G+LDK G+
Sbjct: 328 AIGIAQMTTASMATCDHGVVATIKRVIMDRDVYPVRWGLGPKAKVKKEMIKDGKLDKFGK 387

Query: 389 PNEHTPSDW 397
           PNE TPSDW
Sbjct: 388 PNEKTPSDW 396

emb|CAB07244.1| Hypothetical protein K01G5.5 [Caenorhabditis elegans]
sp|O17919|NOP50_CAEEL Putative nucleolar protein K01G5.5
ref|NP_499370.1| centromere microtubule binding protein like (50.2 kD) (3L839) [Caenorhabditis elegans]
(445 aa)

Score: 554 bits (1427), Expect: 1.97798e-156
Length: 391, Idn/Pos/Gap = 256/319/3 (65%/81%/0%)

Query:   9 LAEQQRSLSFQIPSDAGENGLSTDSWPLLLKNYDRLNVRTTHYTPIPDAGYSPLKRPIQE  68
           LAE Q+  SFQ+PS      L    WPLLLKNYD+LNVRT HYTP  + G SPLKR I+ 
Sbjct:  15 LAEAQQKGSFQLPSSNETAKLDASQWPLLLKNYDKLNVRTNHYTPHVE-GVSPLKRDIKN  73

Query:  69 YIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKS 128
           YI SG  NLDKP+NPSSHEVV+WIKRILR EKTGHSGTLDP+V+GCLIVCI+R TRL KS
Sbjct:  74 YISSGFFNLDKPSNPSSHEVVSWIKRILRCEKTGHSGTLDPKVSGCLIVCIDRTTRLAKS 133

Query: 129 QQSAGKEYVAVLRLHGMRPELDEATVRRAIETLTGPLYQRPPLISAVKRQLRIRTIYESK 188
           QQ AGKEY+ + +LH      D+  V++A+E LTG L+QRPPLISAVKRQLRIRT+YE+K
Sbjct: 134 QQGAGKEYICIFKLH--EEVEDDRKVKQALEKLTGALFQRPPLISAVKRQLRIRTVYENK 191

Query: 189 LLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTM 248
            +EYDP +++ +F   CE+GTY+RT+CVHLGL+LG GG MQELRR RSG+  E + MVTM
Sbjct: 192 FIEYDPAQQMGIFNCICESGTYVRTICVHLGLILGCGGQMQELRRNRSGICDENENMVTM 251

Query: 249 HDVLDAQWLFDTTKDESYLRRVIKPLESLLVHHKRIVIKDSCVNAVCYGAKLMLPGVLRY 308
           HDVLDAQ+L DT KDESY+R +++PLE+LL  HKR+V+KDSC+NA+CYGAK+++PG+LRY
Sbjct: 252 HDVLDAQYLLDTQKDESYMRHIVRPLEALLTQHKRVVVKDSCINAICYGAKILIPGILRY 311

Query: 309 ENDIECGEEVVIMTTKGEAVALAIAHMSTSEIASCDHGVVARIKRVVMERDLYPRRWGLG 368
           ++DIE G+E+VIM+TKGEA+ +AIA M+TS IAS DHGVVA+ KRV+MERD+Y R+WGLG
Sbjct: 312 DDDIEVGKEIVIMSTKGEAICIAIAQMNTSTIASVDHGVVAKSKRVIMERDVYGRKWGLG 371

Query: 369 PVASRKKAMIQRGELDKHGRPNEHTPSDWRR 399
           PVAS+KK M++ G LDK G+PN+ TP  W +
Sbjct: 372 PVASKKKQMVKDGLLDKFGKPNDTTPKSWAK 402

prf||2103261A nuclear protein NAP57
(466 aa)

Score: 553 bits (1425), Expect: 3.72922e-156
Length: 397, Idn/Pos/Gap = 285/334/3 (71%/84%/0%)

Query:   3 PKSSASLAEQQRSLSFQIPSDAGENGLSTDSWPLLLKNYDRLNVRTTHYTPIPDAGYSPL  62
           P   A +AE Q +  F I  ++    L T  WPLLLKN+DRLNVRTTHYTPIP  G +PL
Sbjct:  22 PLPEADVAEIQHAEDFLIKPESKAAQLDTSQWPLLLKNFDRLNVRTTHYTPIP-CGSNPL  80

Query:  63 KRPIQEYIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERA 122
           KR I EY+R+G INLDKP+NPSSHEVVAWI+RILRVEKTGHSGTLDP+VTGCLIVCIERA
Sbjct:  81 KREIGEYVRTGFINLDKPSNPSSHEVVAWIRRILRVEKTGHSGTLDPKVTGCLIVCIERA 140

Query: 123 TRLVKSQQSAGKEYVAVLRLHGMRPELDEATVRRAIETLTGPLYQRPPLISAVKRQLRIR 182
           TRLVKSQQSAGKEYV V+RLH        A + RA+ETLTG L+QRPPLI+AVKRQLR+R
Sbjct: 141 TRLVKSQQSAGKEYVGVVRLHNAIE--GTAQLSRALETLTGALFQRPPLIAAVKRQLRVR 198

Query: 183 TIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEY 242
           TIYES+++EYDP+RRL +FWVSCEAGTYIRTLCVHLGLLLGVGG MQELRRVRSGV  E 
Sbjct: 199 TIYESRVVEYDPERRLGVFWVSCEAGTYIRTLCVHLGLLLGVGGQMQELRRVRSGVVGER 258

Query: 243 DGMVTMHDVLDAQWLFDTTKDESYLRRVIKPLESLLVHHKRIVIKDSCVNAVCYGAKLML 302
           D MVTMHDVLDAQ+L+D  +DESYLRRV+ PLE LL  HKR+V+KDS VNA+CYGAK+ML
Sbjct: 259 DHMVTMHDVLDAQYLYDHHRDESYLRRVVFPLEKLLTSHKRLVMKDSAVNAICYGAKIML 318

Query: 303 PGVLRYENDIECGEEVVIMTTKGEAVALAIAHMSTSEIASCDHGVVARIKRVVMERDLYP 362
           PG+LRYE+ IE  +EVV++TTKGEAV +AIA M+T+ I++CDHGVVA+IKRV+MERD YP
Sbjct: 319 PGLLRYEDGIEVNQEVVVITTKGEAVCVAIALMTTAVISTCDHGVVAKIKRVIMERDTYP 378

Query: 363 RRWGLGPVASRKKAMIQRGELDKHGRPNEHTPSDWRR 399
           R+WGLGP AS+KK +I++G LDKHGRP + TP+ W R
Sbjct: 379 RKWGLGPKASQKKQLIKQGLLDKHGRPTDGTPASWTR 415

emb|CAE71406.1| Hypothetical protein CBG18316 [Caenorhabditis briggsae]
(445 aa)

Score: 553 bits (1425), Expect: 3.82374e-156
Length: 391, Idn/Pos/Gap = 258/318/3 (65%/81%/0%)

Query:   9 LAEQQRSLSFQIPSDAGENGLSTDSWPLLLKNYDRLNVRTTHYTPIPDAGYSPLKRPIQE  68
           LAE Q+  SFQ+PS      L    WPLLLKNYD+LNVRT HYTP  + G SPLKR I+ 
Sbjct:  15 LAEAQQKGSFQLPSSNETAKLDASQWPLLLKNYDKLNVRTNHYTPHVE-GVSPLKRDIKN  73

Query:  69 YIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKS 128
           YI SG  NLDKP+NPSSHEVV+WIKRILR EKTGHSGTLDP+V+GCLIVCI+R TRL KS
Sbjct:  74 YISSGFFNLDKPSNPSSHEVVSWIKRILRCEKTGHSGTLDPKVSGCLIVCIDRTTRLAKS 133

Query: 129 QQSAGKEYVAVLRLHGMRPELDEATVRRAIETLTGPLYQRPPLISAVKRQLRIRTIYESK 188
           QQ AGKEY+ + +LH      DE  V++A+E LTG L+QRPPLISAVKRQLRIRT+YE+K
Sbjct: 134 QQGAGKEYICIFKLH--EEVEDERKVKQALEKLTGALFQRPPLISAVKRQLRIRTVYENK 191

Query: 189 LLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTM 248
            +EYDP +++ +F   CE+GTY+RT+CVHLGL+LG GG MQELRR RSG+  E + MVTM
Sbjct: 192 FIEYDPAQQMGIFNCICESGTYVRTICVHLGLILGCGGQMQELRRNRSGICDENENMVTM 251

Query: 249 HDVLDAQWLFDTTKDESYLRRVIKPLESLLVHHKRIVIKDSCVNAVCYGAKLMLPGVLRY 308
           HDVLDAQ++ DT KDESY+R +++PLE+LL  HKR+V+KDSCVNA+CYGAK+++PG+LRY
Sbjct: 252 HDVLDAQYMLDTQKDESYMRHIVRPLEALLTQHKRVVVKDSCVNAICYGAKILIPGILRY 311

Query: 309 ENDIECGEEVVIMTTKGEAVALAIAHMSTSEIASCDHGVVARIKRVVMERDLYPRRWGLG 368
           ++DIE G+E+VIMTTKGEA+ +AIA MSTS IAS DHG+VA+ KRV+MERD+Y R+WGLG
Sbjct: 312 DDDIEVGKEIVIMTTKGEAICIAIAQMSTSTIASVDHGIVAKSKRVIMERDVYGRKWGLG 371

Query: 369 PVASRKKAMIQRGELDKHGRPNEHTPSDWRR 399
           PVAS+KK M++ G LDK G+PN  TP  W +
Sbjct: 372 PVASKKKQMVKDGLLDKFGKPNITTPKSWAK 402

gb|AAH09928.1| Dyskerin [Homo sapiens]
(514 aa)

Score: 553 bits (1425), Expect: 4.02004e-156
Length: 392, Idn/Pos/Gap = 279/334/5 (71%/85%/1%)

Query:   9 LAEQQRSLSFQIPSDAGENGLSTDSWPLLLKNYDRLNVRTTHYTPIPDAGYSPLKRPIQE  68
           +AE Q +  F I  ++    L T  WPLLLKN+D+LNVRTTHYTP+   G +PLKR I +
Sbjct:  27 VAEIQHAEEFLIKPESKVAKLDTSQWPLLLKNFDKLNVRTTHYTPLA-CGSNPLKREIGD  85

Query:  69 YIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKS 128
           YIR+G INLDKP+NPSSHEVVAWI+RILRVEKTGHSGTLDP+VTGCLIVCIERATRLVKS
Sbjct:  86 YIRTGFINLDKPSNPSSHEVVAWIRRILRVEKTGHSGTLDPKVTGCLIVCIERATRLVKS 145

Query: 129 QQSAGKEYVAVLRLHGMRPELDEAT-VRRAIETLTGPLYQRPPLISAVKRQLRIRTIYES 187
           QQSAGKEYV ++RLH     ++  T + RA+ETLTG L+QRPPLI+AVKRQLR+RTIYES
Sbjct: 146 QQSAGKEYVGIVRLHN---AIEGGTQLSRALETLTGALFQRPPLIAAVKRQLRVRTIYES 202

Query: 188 KLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVT 247
           K++EYDP+RRL +FWVSCEAGTYIRTLCVHLGLLLGVGG MQELRRVRSGV SE D MVT
Sbjct: 203 KMIEYDPERRLGIFWVSCEAGTYIRTLCVHLGLLLGVGGQMQELRRVRSGVMSEKDHMVT 262

Query: 248 MHDVLDAQWLFDTTKDESYLRRVIKPLESLLVHHKRIVIKDSCVNAVCYGAKLMLPGVLR 307
           MHDVLDAQWL+D  KDESYLRR + PLE LL  HKR+V+KDS VNA+CYGAK+MLPGVLR
Sbjct: 263 MHDVLDAQWLYDNHKDESYLRRFVYPLEKLLTSHKRLVMKDSAVNAICYGAKIMLPGVLR 322

Query: 308 YENDIECGEEVVIMTTKGEAVALAIAHMSTSEIASCDHGVVARIKRVVMERDLYPRRWGL 367
           YE+ IE  +E+V++TTKGEA+ +AIA M+T+ I++CDHG+VA+IKRV+MERD YPR+WGL
Sbjct: 323 YEDGIEVNQEIVVITTKGEAICMAIALMTTAVISTCDHGIVAKIKRVIMERDTYPRKWGL 382

Query: 368 GPVASRKKAMIQRGELDKHGRPNEHTPSDWRR 399
           GP AS+KK MI++G LDKHG+P + TP+ W++
Sbjct: 383 GPKASQKKLMIKQGLLDKHGKPTDSTPATWKQ 414

emb|CAB72185.1| putative protein [Arabidopsis thaliana]
gb|AAO41863.1| unknown protein [Arabidopsis thaliana]
ref|NP_191274.1| dyskerin, putative / nucleolar protein NAP57, putative [Arabidopsis thaliana]
pir||T47775 hypothetical protein F24I3.230 - Arabidopsis thaliana
gb|AAF43210.2| putative pseudouridine synthase [Arabidopsis thaliana]
(565 aa)

Score: 551 bits (1420), Expect: 1.29283e-155
Length: 372, Idn/Pos/Gap = 282/324/3 (75%/87%/0%)

Query:  28 GLSTDSWPLLLKNYDRLNVRTTHYTPIPDAGYSPLKRPIQEYIRSGVINLDKPANPSSHE  87
            + T  WP+LLKNYDRLNVRT HYTPI  AG+SPLKRP+QEYIR GVINLDKPANPSSHE
Sbjct:  37 AIDTSQWPILLKNYDRLNVRTGHYTPI-SAGHSPLKRPLQEYIRYGVINLDKPANPSSHE  95

Query:  88 VVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAGKEYVAVLRLHGMRP 147
           VVAWIKRILRVEKTGHSGTLDP+VTG LIVCI+RATRLVKSQQ AGKEYV V RLH   P
Sbjct:  96 VVAWIKRILRVEKTGHSGTLDPKVTGNLIVCIDRATRLVKSQQGAGKEYVCVARLHSAVP 155

Query: 148 ELDEATVRRAIETLTGPLYQRPPLISAVKRQLRIRTIYESKLLEYDPKRRLVLFWVSCEA 207
             D A V RA+E+LTG ++QRPPLISAVKRQLRIRTIYESKLLEYD  R LV+FWVSCEA
Sbjct: 156 --DVAKVARALESLTGAVFQRPPLISAVKRQLRIRTIYESKLLEYDADRHLVVFWVSCEA 213

Query: 208 GTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYL 267
           GTYIRT+CVHLGLLLGVGGHMQELRRVRSG+  E + MVTMHDV+DAQ+++D ++DESYL
Sbjct: 214 GTYIRTMCVHLGLLLGVGGHMQELRRVRSGILGENNNMVTMHDVMDAQFVYDNSRDESYL 273

Query: 268 RRVIKPLESLLVHHKRIVIKDSCVNAVCYGAKLMLPGVLRYENDIECGEEVVIMTTKGEA 327
           RRVI PLE +L  +KR+V+KDS VNA+CYGAKLM+PG+LR+ENDI+ G EVV+MTTKGEA
Sbjct: 274 RRVIMPLEMILTSYKRLVVKDSAVNAICYGAKLMIPGLLRFENDIDVGTEVVLMTTKGEA 333

Query: 328 VALAIAHMSTSEIASCDHGVVARIKRVVMERDLYPRRWGLGPVASRKKAMIQRGELDKHG 387
           +A+ IA M+TS +A+CDHGVVA+IKRVVM+RD YPR+WGLGP AS KK +I  G+LDKHG
Sbjct: 334 IAVGIAEMTTSVMATCDHGVVAKIKRVVMDRDTYPRKWGLGPRASMKKKLIADGKLDKHG 393

Query: 388 RPNEHTPSDWRR 399
           +PNE TP +W R
Sbjct: 394 KPNEKTPVEWSR 405

gb|AAF77119.1| Cbf5p [Euglena gracilis]
(467 aa)

Score: 551 bits (1419), Expect: 1.8977e-155
Length: 417, Idn/Pos/Gap = 265/329/6 (63%/78%/1%)

Query:   9 LAEQQRSLSFQIPSDAGENGLSTDS--WPLLLKNYDRLNVRTTHYTPIPDAGYSPLKRPI  66
           +A+ Q    F IP+++GE G + DS  WPLLLKNYD+LNVR+ HYTPIP  G++PLKRPI
Sbjct:   1 MAKAQWENDFSIPTESGEKGAALDSSEWPLLLKNYDKLNVRSAHYTPIPQ-GHTPLKRPI  59

Query:  67 QEYIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLV 126
           + Y++ G +NLDKP+NPSSHEVV+W+KRIL+VEKTGH+GTLDP+VTG L++CIERATRLV
Sbjct:  60 KAYLQYGCLNLDKPSNPSSHEVVSWLKRILKVEKTGHAGTLDPKVTGSLLICIERATRLV 119

Query: 127 KSQQSAGKEYVAVLRLHGMRPELDEATVRRAIETLTGPLYQRPPLISAVKRQLRIRTIYE 186
           KSQQ+AGKEYV VLRLH      DEA + +A+E LTG ++QRPP+++AVKR LRIRTIYE
Sbjct: 120 KSQQNAGKEYVGVLRLHDALK--DEAQLLKALEDLTGAVFQRPPVVAAVKRTLRIRTIYE 177

Query: 187 SKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMV 246
           SKLL++D  R L +FW+SCEAGTY+RTLCVHLG +LG  GHM ELRR R+G   E DGMV
Sbjct: 178 SKLLDFDNDRHLAVFWISCEAGTYVRTLCVHLGFVLGTAGHMAELRRTRTGHLGENDGMV 237

Query: 247 TMHDVLDAQWLFDTTKDESYLRRVIKPLESLLVHHKRIVIKDSCVNAVCYGAKLMLPGVL 306
           TMHDVLDA  L+D   DESYLRR + P E LL  +KR+V+KD+ VNA+CYGAKLM+PG+L
Sbjct: 238 TMHDVLDAMHLYDQEGDESYLRRTVMPCELLLTAYKRVVVKDTAVNAICYGAKLMIPGLL 297

Query: 307 RYENDIECGEEVVIMTTKGEAVALAIAHMSTSEIASCDHGVVARIKRVVMERDLYPRRWG 366
           R+EN IE  E +V+MTTKGEA+AL IA M+T+++ +CDHG+VA+IKRVVM+RD YPRRWG
Sbjct: 298 RFENGIEVNEVIVLMTTKGEAIALGIALMTTADMGTCDHGIVAKIKRVVMDRDTYPRRWG 357

Query: 367 LGPVASRKKAMIQRGELDKHGRPNEHTPSDWRRVQ-PELESAPSRMERQAGPPVRPP 422
           LGPVA +KK MI+RG LDKHGR  E TP+ W  V      S    M R+    + PP
Sbjct: 358 LGPVALKKKEMIERGHLDKHGRRTEATPNSWWYVDYSGCGSNEEAMNREGNKSLGPP 414

emb|CAD70854.1| probable CENTROMERE/MICROTUBULE BINDING PROTEIN CBF5 [Neurospora crassa]
ref|XP_326783.1| hypothetical protein [Neurospora crassa]
gb|EAA31591.1| hypothetical protein [Neurospora crassa]
(480 aa)

Score: 550 bits (1417), Expect: 3.29146e-155
Length: 379, Idn/Pos/Gap = 271/310/3 (71%/81%/0%)

Query:  20 IPSDAGENGLSTDSWPLLLKNYDRLNVRTTHYTPIPDAGYSPLKRPIQEYIRSGVINLDK  79
           I   A E  + T  WPLLLKNY  L VRT H+TPIP AG SP KR I+ Y+ SGVINLDK
Sbjct:   9 IKPQATEPAVDTSEWPLLLKNYSNLLVRTGHFTPIP-AGSSPSKRDIKSYVSSGVINLDK  67

Query:  80 PANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAGKEYVAV 139
           P+NPSSHEVVAWIKR+LRVEKTGHSGTLDP+VTGCLIVC++RATRLVK+QQ AGKEYV V
Sbjct:  68 PSNPSSHEVVAWIKRMLRVEKTGHSGTLDPKVTGCLIVCVDRATRLVKAQQGAGKEYVCV 127

Query: 140 LRLHGMRPELDEATVRRAIETLTGPLYQRPPLISAVKRQLRIRTIYESKLLEYDPKRRLV 199
           +R H   P   EA    A+ETLTG L+QRPPLISAVKRQLRIR+IYESKL+E+D  R L 
Sbjct: 128 IRFHDSVPG-GEAAFASALETLTGALFQRPPLISAVKRQLRIRSIYESKLIEFDNDRHLG 186

Query: 200 LFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDG-MVTMHDVLDAQWLF 258
           +FWVSCEAGTYIRTLCVHLGLLLGVG HMQELRRVRSG+ SE +G MVT+HDVLDAQW F
Sbjct: 187 VFWVSCEAGTYIRTLCVHLGLLLGVGAHMQELRRVRSGIMSEDNGSMVTLHDVLDAQWQF 246

Query: 259 DTTKDESYLRRVIKPLESLLVHHKRIVIKDSCVNAVCYGAKLMLPGVLRYENDIECGEEV 318
           D   DE+ LR+VI+PLE+LL  +KRIV+KDS VNAVCYGAKLMLPG+LR+E  IE  EEV
Sbjct: 247 DNGGDETALRKVIQPLETLLTTYKRIVVKDSAVNAVCYGAKLMLPGLLRFEKGIETHEEV 306

Query: 319 VIMTTKGEAVALAIAHMSTSEIASCDHGVVARIKRVVMERDLYPRRWGLGPVASRKKAMI 378
           V+MTTKGEA+A+ IA M+  E+ SCDHGVVA++KR +MERDLYPRRWGLGPVA  KK + 
Sbjct: 307 VLMTTKGEAIAIGIAQMNGVEMLSCDHGVVAKVKRCIMERDLYPRRWGLGPVALEKKKLK 366

Query: 379 QRGELDKHGRPNEHTPSDW 397
             G+LDK GRPN  TP+ W
Sbjct: 367 SDGKLDKFGRPNAETPAKW 385

emb|CAG90524.1| unnamed protein product [Debaryomyces hansenii CBS767]
ref|XP_462038.1| unnamed protein product [Debaryomyces hansenii]
(472 aa)

Score: 547 bits (1410), Expect: 1.91416e-154
Length: 394, Idn/Pos/Gap = 267/325/12 (67%/82%/3%)

Query:  31 TDSWPLLLKNYDRLNVRTTHYTPIPDAGYSPLKRPIQEYIRSGVINLDKPANPSSHEVVA  90
           T  WPLLLKNYD+L VR+ HYTPIP +G SPLKR ++ YI SG+INLDKP+NPSSHEVVA
Sbjct:  18 TSEWPLLLKNYDKLLVRSGHYTPIP-SGCSPLKRDLKSYISSGIINLDKPSNPSSHEVVA  76

Query:  91 WIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAGKEYVAVLRLHGMRPELD 150
           WIKRILR EKTGHSGTLDP+VTGCLIVCI+RATRLVKSQQ AGKEYV ++RLH    EL 
Sbjct:  77 WIKRILRSEKTGHSGTLDPKVTGCLIVCIDRATRLVKSQQGAGKEYVCIVRLHD---ELK 133

Query: 151 EAT-VRRAIETLTGPLYQRPPLISAVKRQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGT 209
           +A  + R++E LTG L+QRPPLISAVKRQLR+RTIY+S L+E+D KR L +FW SCEAGT
Sbjct: 134 DAKEMGRSLENLTGALFQRPPLISAVKRQLRVRTIYDSNLIEFDNKRGLGVFWASCEAGT 193

Query: 210 YIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRR 269
           Y+RTLCVHLG+LLGVGGHMQELRRVRSG  SE D +VT+HDVLDAQ+++D T+DESYLR+
Sbjct: 194 YMRTLCVHLGMLLGVGGHMQELRRVRSGALSENDNLVTLHDVLDAQYVYDNTRDESYLRK 253

Query: 270 VIKPLESLLVHHKRIVIKDSCVNAVCYGAKLMLPGVLRYENDIECGEEVVIMTTKGEAVA 329
           +I+PLE+LLV +KRIV+KDS VN+VCYGAKLM+PG+LRYE  IE  +EVV+MTTKGEA+A
Sbjct: 254 IIQPLETLLVGYKRIVVKDSAVNSVCYGAKLMIPGLLRYEEGIELYDEVVLMTTKGEAIA 313

Query: 330 LAIAHMSTSEIASCDHGVVARIKRVVMERDLYPRRWGLGPVASRKKAMIQRGELDKHGRP 389
           + IA M+T ++  CDHGVVA++KR +MERD YPRRWGLGPVA +KK +   G+LDK+GR 
Sbjct: 314 IGIAQMTTVDLQGCDHGVVAKVKRCIMERDTYPRRWGLGPVAQKKKQLKADGKLDKYGRA 373

Query: 390 NEHTPSDWRRVQPELESAPSRMERQAGPPVRPPK 423
           NE+TP  W++   + +  P+       PPV   K
Sbjct: 374 NENTPETWKKDYKDHDDEPA-------PPVPESK 400

gb|EAK80867.1| hypothetical protein UM00685.1 [Ustilago maydis 521]
ref|XP_398300.1| hypothetical protein UM00685.1 [Ustilago maydis 521]
(496 aa)

Score: 547 bits (1409), Expect: 2.3779e-154
Length: 393, Idn/Pos/Gap = 287/330/4 (73%/83%/1%)

Query:   8 SLAEQQRSLSFQIPSDAGENGLSTDSWPLLLKNYDRLNVRTTHYTPIPDAGYSPLKRPIQ  67
           S+AE Q    F I  +     L+T  WPLLLKNYD+L VR++H+TPIP  G SPLKR +Q
Sbjct:   8 SVAEVQEKGDFMIKPENSGPKLNTSEWPLLLKNYDQLLVRSSHFTPIPH-GCSPLKRDLQ  66

Query:  68 EYIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVK 127
            YI+SGVINLDKP+NPSSHEVV+W++RILRVEKTGHSGTLDP+VTGCLIVCI+RATRLVK
Sbjct:  67 SYIKSGVINLDKPSNPSSHEVVSWLRRILRVEKTGHSGTLDPKVTGCLIVCIDRATRLVK 126

Query: 128 SQQSAGKEYVAVLRLHGMRPELDEATVRRAIETLTGPLYQRPPLISAVKRQLRIRTIYES 187
           SQQ AGKEYVAVLRLH      D   + RAIETLTG L+QRPPLISAVKRQLRIRTIYES
Sbjct: 127 SQQGAGKEYVAVLRLHDKLE--DAKKLPRAIETLTGSLFQRPPLISAVKRQLRIRTIYES 184

Query: 188 KLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVT 247
           KL+E+D  R L +FWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSG  SE D +VT
Sbjct: 185 KLIEFDNDRHLAVFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGALSENDSIVT 244

Query: 248 MHDVLDAQWLFDTTKDESYLRRVIKPLESLLVHHKRIVIKDSCVNAVCYGAKLMLPGVLR 307
           MHDVLDAQWL+D  +DE+YLRRVI+PLESLL  +KRIV+KDS VNAVCYGAKLM+PG+LR
Sbjct: 245 MHDVLDAQWLYDNQRDETYLRRVIRPLESLLTGYKRIVVKDSAVNAVCYGAKLMIPGLLR 304

Query: 308 YENDIECGEEVVIMTTKGEAVALAIAHMSTSEIASCDHGVVARIKRVVMERDLYPRRWGL 367
           YE DIE  EEVV+MTTKGEA+ALAIA MST ++++CDHGVVA++KR +MERD YPRRWGL
Sbjct: 305 YEKDIEVHEEVVLMTTKGEAIALAIAQMSTVDLSTCDHGVVAKVKRCIMERDTYPRRWGL 364

Query: 368 GPVASRKKAMIQRGELDKHGRP-NEHTPSDWRR 399
           GP A  KKAMI+ G+LDKHG+  N  TP  W++
Sbjct: 365 GPKAQEKKAMIKTGKLDKHGKAINGVTPDKWKK 397

emb|CAG59887.1| unnamed protein product [Candida glabrata CBS138]
ref|XP_446954.1| unnamed protein product [Candida glabrata]
(474 aa)

Score: 546 bits (1408), Expect: 3.37587e-154
Length: 370, Idn/Pos/Gap = 269/318/3 (72%/85%/0%)

Query:  30 STDSWPLLLKNYDRLNVRTTHYTPIPDAGYSPLKRPIQEYIRSGVINLDKPANPSSHEVV  89
           +   WPLLLK+YD+L VR+ HYTPIP AG SPLKR ++ YI SGVINLDKP+NPSSHEVV
Sbjct:  17 NASEWPLLLKDYDKLLVRSGHYTPIP-AGSSPLKRDLKSYISSGVINLDKPSNPSSHEVV  75

Query:  90 AWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAGKEYVAVLRLHGMRPEL 149
           AWIKRILR EKTGHSGTLDP+VTGCLIVCI+RATRLVKSQQ AGKEYV ++RLH      
Sbjct:  76 AWIKRILRCEKTGHSGTLDPKVTGCLIVCIDRATRLVKSQQGAGKEYVCIVRLHDALK-- 133

Query: 150 DEATVRRAIETLTGPLYQRPPLISAVKRQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGT 209
           DE  + R++E LTG L+QRPPLISAVKRQLR+RTIY+S L+E+D KR L +FW SCEAGT
Sbjct: 134 DEKDLGRSLENLTGALFQRPPLISAVKRQLRVRTIYDSNLIEFDNKRNLGVFWASCEAGT 193

Query: 210 YIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRR 269
           Y+RTLCVHLG+LLGVGGHMQELRRVRSG  SE D MVT+HDVLDAQW+FD T+DESYLR+
Sbjct: 194 YMRTLCVHLGMLLGVGGHMQELRRVRSGALSENDNMVTLHDVLDAQWVFDNTRDESYLRK 253

Query: 270 VIKPLESLLVHHKRIVIKDSCVNAVCYGAKLMLPGVLRYENDIECGEEVVIMTTKGEAVA 329
           +I+PLE+LLV +KRIV+KDS VNAVCYGAKLM+PG+LRYE  IE  +EVV+MTTKGEA+A
Sbjct: 254 IIQPLETLLVGYKRIVVKDSAVNAVCYGAKLMIPGLLRYEEGIELYDEVVLMTTKGEAIA 313

Query: 330 LAIAHMSTSEIASCDHGVVARIKRVVMERDLYPRRWGLGPVASRKKAMIQRGELDKHGRP 389
           +AIA MST ++A+CDHGVVA +KR +MERDLYPRRWGLGP+A +KK +   G+LDK+GR 
Sbjct: 314 VAIAQMSTVDLATCDHGVVATVKRCIMERDLYPRRWGLGPIAQKKKQLKADGKLDKYGRV 373

Query: 390 NEHTPSDWRR 399
           NE TP DW++
Sbjct: 374 NESTPEDWKK 383

emb|CAH00369.1| CBF5_KLULA [Kluyveromyces lactis NRRL Y-1140]
ref|XP_453273.1| CBF5_KLULA [Kluyveromyces lactis]
gb|AAC64862.1| centromere-binding factor 5 [Kluyveromyces lactis]
sp|O13473|CBF5_KLULA Centromere/microtubule binding protein CBF5 (Centromere-binding factor 5) (Small nucleolar RNP protein CBF5) (H/ACA snoRNP protein CBF5)
(474 aa)

Score: 545 bits (1405), Expect: 7.09399e-154
Length: 393, Idn/Pos/Gap = 271/328/3 (68%/83%/0%)

Query:  15 SLSFQIPSDAGENGLSTDSWPLLLKNYDRLNVRTTHYTPIPDAGYSPLKRPIQEYIRSGV  74
           S  F I  ++     +T  WPLLLK+YD+L VR+ HYTPIP AG SPLKR ++ YI SGV
Sbjct:   2 SDEFVIKPESVSPSSNTSEWPLLLKDYDKLLVRSGHYTPIP-AGASPLKRDLKSYISSGV  60

Query:  75 INLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAGK 134
           INLDKP+NPSSHEVVAWIKRILR EKTGHSGTLDP+VTGCLIVC++RATRLVKSQQ AGK
Sbjct:  61 INLDKPSNPSSHEVVAWIKRILRCEKTGHSGTLDPKVTGCLIVCVDRATRLVKSQQGAGK 120

Query: 135 EYVAVLRLHGMRPELDEATVRRAIETLTGPLYQRPPLISAVKRQLRIRTIYESKLLEYDP 194
           EYV ++RLH      DE  + R +E LTG L+QRPPLISAVKRQLR+RTIY+S L+E+D 
Sbjct: 121 EYVCIVRLHDALK--DEKELGRGLENLTGALFQRPPLISAVKRQLRVRTIYDSNLIEFDN 178

Query: 195 KRRLVLFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDA 254
           KR L +FW SCEAGTY+RTLCVHLG+LLGVGGHMQELRRVRSG  SE D +VT+HDV+DA
Sbjct: 179 KRNLGVFWASCEAGTYMRTLCVHLGMLLGVGGHMQELRRVRSGALSENDNLVTLHDVMDA 238

Query: 255 QWLFDTTKDESYLRRVIKPLESLLVHHKRIVIKDSCVNAVCYGAKLMLPGVLRYENDIEC 314
           QW++D T+DESYLR++I+PLE+LLV +KRIV+KDS VNAVCYGAKLM+PG+LRYE  IE 
Sbjct: 239 QWVYDNTRDESYLRKIIQPLETLLVGYKRIVVKDSAVNAVCYGAKLMIPGLLRYEEGIEL 298

Query: 315 GEEVVIMTTKGEAVALAIAHMSTSEIASCDHGVVARIKRVVMERDLYPRRWGLGPVASRK 374
            +EVV++TTKGEA+A+AIA MST ++A+CDHGVVA++KR +MERDLYPRRWGLGP+A +K
Sbjct: 299 YDEVVLITTKGEAIAVAIAQMSTVDLATCDHGVVAKVKRCIMERDLYPRRWGLGPIAQKK 358

Query: 375 KAMIQRGELDKHGRPNEHTPSDWRRVQPELESA 407
           K M   G+LDK+GR NE+TP  W++    LE+A
Sbjct: 359 KQMKADGKLDKYGRANENTPETWKKTYVSLENA 391

gb|EAL35749.1| hypothetical protein Chro.30435 [Cryptosporidium hominis]
(518 aa)

Score: 541 bits (1395), Expect: 1.18048e-152
Length: 382, Idn/Pos/Gap = 257/308/3 (67%/80%/0%)

Query:  20 IPSDAGENGLSTDSWPLLLKNYDRLNVRTTHYTPIPDAGYSPLKRPIQEYIRSGVINLDK  79
           I  ++    + T +WPLLLKNY +LNVRT HYTP+P  G SPL R + +Y+  G+INLDK
Sbjct:  19 IKPESKSQPIDTSNWPLLLKNYSKLNVRTGHYTPLP-YGNSPLNRNLTDYLSYGIINLDK  77

Query:  80 PANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAGKEYVAV 139
           PANPSSHEVVAWIK+ILR EKTGHSGTLDP+VTGCL+VC+ RATRLVKSQQSAGKEYV +
Sbjct:  78 PANPSSHEVVAWIKKILRCEKTGHSGTLDPKVTGCLLVCLNRATRLVKSQQSAGKEYVCI 137

Query: 140 LRLHGMRPELDEATVRRAIETLTGPLYQRPPLISAVKRQLRIRTIYESKLLEYDPKRRLV 199
           +R H       ++ V R +ETLTG L+QRPP+ISAVKRQLR+R+IY+SKLL+YD KR L 
Sbjct: 138 VRFHSSVG--GKSAVSRCLETLTGALFQRPPVISAVKRQLRVRSIYDSKLLDYDEKRNLA 195

Query: 200 LFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFD 259
           +FW  CEAGTYIRT+CVH+GLLLGVG HMQELRRVRSG  SE D MVTMHD+LDAQ++ D
Sbjct: 196 VFWAKCEAGTYIRTMCVHMGLLLGVGAHMQELRRVRSGCLSENDNMVTMHDILDAQYMLD 255

Query: 260 TTKDESYLRRVIKPLESLLVHHKRIVIKDSCVNAVCYGAKLMLPGVLRYENDIECGEEVV 319
             +DESYLRR+I PLE LL    RIV+KDSCVNA+CYGAKLM+PGVLR++N I+ G EVV
Sbjct: 256 NYRDESYLRRIISPLELLLTDLPRIVVKDSCVNAICYGAKLMIPGVLRFDNGIDVGTEVV 315

Query: 320 IMTTKGEAVALAIAHMSTSEIASCDHGVVARIKRVVMERDLYPRRWGLGPVASRKKAMIQ 379
           +MTTKGEA+A+ +A M+T+ IAS DHGVVA IKRV+MERD Y  RWG GP AS KK +I 
Sbjct: 316 MMTTKGEAIAIGVAQMTTAVIASVDHGVVAIIKRVIMERDTYDMRWGHGPRASEKKKLIL 375

Query: 380 RGELDKHGRPNEHTPSDWRRVQ 401
            G+LDKHG+PNE TP  W + +
Sbjct: 376 GGKLDKHGKPNEQTPESWLKYE 397

gb|EAK89243.1| Cbf5p; centromere-binding factor 5 like PUA domain containing protein with a type I pseudouridine synthase domain, transcript identified by EST [Cryptosporidium parvum]
(520 aa)

Score: 541 bits (1394), Expect: 1.38327e-152
Length: 382, Idn/Pos/Gap = 257/308/3 (67%/80%/0%)

Query:  20 IPSDAGENGLSTDSWPLLLKNYDRLNVRTTHYTPIPDAGYSPLKRPIQEYIRSGVINLDK  79
           I  ++    + T +WPLLLKNY +LNVRT HYTP+P  G SPL R + +Y+  G+INLDK
Sbjct:  21 IKPESKSQPIDTSNWPLLLKNYSKLNVRTGHYTPLP-YGNSPLNRNLADYLSYGIINLDK  79

Query:  80 PANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAGKEYVAV 139
           PANPSSHEVVAWIK+ILR EKTGHSGTLDP+VTGCL+VC+ RATRLVKSQQSAGKEYV +
Sbjct:  80 PANPSSHEVVAWIKKILRCEKTGHSGTLDPKVTGCLLVCLNRATRLVKSQQSAGKEYVCI 139

Query: 140 LRLHGMRPELDEATVRRAIETLTGPLYQRPPLISAVKRQLRIRTIYESKLLEYDPKRRLV 199
           +R H       ++ V R +ETLTG L+QRPP+ISAVKRQLR+R+IY+SKLL+YD KR L 
Sbjct: 140 VRFHSSVG--GKSAVSRCLETLTGALFQRPPVISAVKRQLRVRSIYDSKLLDYDEKRNLA 197

Query: 200 LFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFD 259
           +FW  CEAGTYIRT+CVH+GLLLGVG HMQELRRVRSG  SE D MVTMHD+LDAQ++ D
Sbjct: 198 VFWAKCEAGTYIRTMCVHMGLLLGVGAHMQELRRVRSGCLSENDNMVTMHDILDAQYMLD 257

Query: 260 TTKDESYLRRVIKPLESLLVHHKRIVIKDSCVNAVCYGAKLMLPGVLRYENDIECGEEVV 319
             +DESYLRR+I PLE LL    RIV+KDSCVNA+CYGAKLM+PGVLR++N I+ G EVV
Sbjct: 258 NYRDESYLRRIISPLELLLTDLPRIVVKDSCVNAICYGAKLMIPGVLRFDNGIDVGTEVV 317

Query: 320 IMTTKGEAVALAIAHMSTSEIASCDHGVVARIKRVVMERDLYPRRWGLGPVASRKKAMIQ 379
           +MTTKGEA+A+ +A M+T+ IAS DHGVVA IKRV+MERD Y  RWG GP AS KK +I 
Sbjct: 318 MMTTKGEAIAIGVAQMTTAVIASVDHGVVAIIKRVIMERDTYDMRWGHGPRASEKKKLIL 377

Query: 380 RGELDKHGRPNEHTPSDWRRVQ 401
            G+LDKHG+PNE TP  W + +
Sbjct: 378 GGKLDKHGKPNEQTPESWLKYE 399

emb|CAB10131.1| SPAC29A4.04c [Schizosaccharomyces pombe]
ref|NP_594878.1| centromere/microtubule binding protein cbf5 [Schizosaccharomyces pombe]
pir||T38485 centromere/microtubule binding protein cbf5 - fission yeast  (Schizosaccharomyces pombe)
sp|O14007|CBF5_SCHPO Centromere/microtubule binding protein cbf5 (Centromere-binding factor 5) (Small nucleolar RNP protein cbf5) (H/ACA snoRNP protein cbf5)
(474 aa)

Score: 536 bits (1381), Expect: 4.09362e-151
Length: 379, Idn/Pos/Gap = 275/324/3 (72%/85%/0%)

Query:  21 PSDAGENGLSTDSWPLLLKNYDRLNVRTTHYTPIPDAGYSPLKRPIQEYIRSGVINLDKP  80
           P     + + T  WPLLLKN+D+L VRT HYTPIP  G +PLKRPI EY+ SGVINLDKP
Sbjct:  14 PEATSASKIDTAEWPLLLKNFDKLLVRTGHYTPIP-CGNNPLKRPIAEYVSSGVINLDKP  72

Query:  81 ANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAGKEYVAVL 140
           ANPSSHEVVAW+K+ILRVEKTGHSGTLDP+VTGCLI+C +RATRLVKSQQSAGKEYV VL
Sbjct:  73 ANPSSHEVVAWVKKILRVEKTGHSGTLDPKVTGCLIICNDRATRLVKSQQSAGKEYVCVL 132

Query: 141 RLHGMRPELDEATVRRAIETLTGPLYQRPPLISAVKRQLRIRTIYESKLLEYDPKRRLVL 200
           RLH       E  V  AIETLTG L+QRPPLISAVKRQLRIR+IYESKL+E+D +R L +
Sbjct: 133 RLHDSVE--GERNVASAIETLTGALFQRPPLISAVKRQLRIRSIYESKLIEFDNERNLAV 190

Query: 201 FWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDT 260
           FW SCEAGTY+RTLCVHLGLLLGVGGHMQELRRVRSG  SE D +VTMHDVLDAQW++D 
Sbjct: 191 FWASCEAGTYMRTLCVHLGLLLGVGGHMQELRRVRSGCLSENDDIVTMHDVLDAQWIYDN 250

Query: 261 TKDESYLRRVIKPLESLLVHHKRIVIKDSCVNAVCYGAKLMLPGVLRYENDIECGEEVVI 320
           T+DESYLRRVI+PLESLLV +KRIV+KDS VNA+CYGAKLM+PG+LRYE  IE  EE+V+
Sbjct: 251 TRDESYLRRVIRPLESLLVGYKRIVVKDSAVNAICYGAKLMIPGLLRYEAGIEVNEEIVL 310

Query: 321 MTTKGEAVALAIAHMSTSEIASCDHGVVARIKRVVMERDLYPRRWGLGPVASRKKAMIQR 380
           +TTKGEA+A+ IA MST E+++CDHGVVA++KR +MERD+YPRRWGLGP + +KK + + 
Sbjct: 311 ITTKGEAIAVGIAQMSTVELSTCDHGVVAKVKRCIMERDVYPRRWGLGPQSMKKKTLKKE 370

Query: 381 GELDKHGRPNEHTPSDWRR 399
           G+LDK+GRPNE+TP+DW +
Sbjct: 371 GKLDKYGRPNENTPADWSK 389

emb|CAB85492.1| putative kinetochore protein [Hordeum vulgare subsp. vulgare]
(405 aa)

Score: 534 bits (1375), Expect: 2.04866e-150
Length: 367, Idn/Pos/Gap = 259/309/4 (70%/84%/1%)

Query:   6 SASLAEQQ-RSLSFQIPSDAGENGLSTDSWPLLLKNYDRLNVRTTHYTPIPDAGYSPLKR  64
           + SLA+ + ++  + I   A    L T +WPLLLKNYDRLNVRT HYTP+P +G+SPLKR
Sbjct:  36 TTSLADAEAKTDGYMIKPQALVPSLDTSTWPLLLKNYDRLNVRTGHYTPLP-SGHSPLKR  94

Query:  65 PIQEYIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATR 124
           P+ EY+R GVINLDKP+NPSSHEVVAWIKR+LRVEKTGHSGTLDP+VTG LIVC++RATR
Sbjct:  95 PLAEYLRYGVINLDKPSNPSSHEVVAWIKRLLRVEKTGHSGTLDPKVTGNLIVCVDRATR 154

Query: 125 LVKSQQSAGKEYVAVLRLHGMRPELDEATVRRAIETLTGPLYQRPPLISAVKRQLRIRTI 184
           LVKSQQ AGKEYV + R H   P  D A V RA+E+LTG ++QRPPLISAVKRQLR+RTI
Sbjct: 155 LVKSQQGAGKEYVCIARFHAAVP--DTARVARALESLTGAVFQRPPLISAVKRQLRVRTI 212

Query: 185 YESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDG 244
           YESKLLE+D +R L +FW+SCEAGTY+RTLCVHLGLLLGVG HMQELRRVRSG+  E D 
Sbjct: 213 YESKLLEHDAERHLAVFWISCEAGTYVRTLCVHLGLLLGVGAHMQELRRVRSGILGEQDN 272

Query: 245 MVTMHDVLDAQWLFDTTKDESYLRRVIKPLESLLVHHKRIVIKDSCVNAVCYGAKLMLPG 304
           MVTMHDV+DA W  D  KDESY+RRV+ PLE +L  +KR+V+KDS VNA+CYGAKLM+PG
Sbjct: 273 MVTMHDVMDAMWALDNHKDESYIRRVVMPLEVILTSYKRLVVKDSAVNAICYGAKLMIPG 332

Query: 305 VLRYENDIECGEEVVIMTTKGEAVALAIAHMSTSEIASCDHGVVARIKRVVMERDLYPRR 364
           +LR+ENDI+ GEEVV+MTTKGEA+A+ IA M T+ +A+CDHG VA+IKRVVM+RD YPR+
Sbjct: 333 LLRFENDIDVGEEVVLMTTKGEAIAIGIAEMPTAVMATCDHGAVAKIKRVVMDRDTYPRK 392

Query: 365 WGLGPVA 371
           WGLGPVA
Sbjct: 393 WGLGPVA 399

gb|EAA77804.1| hypothetical protein FG07206.1 [Gibberella zeae PH-1]
ref|XP_387382.1| hypothetical protein FG07206.1 [Gibberella zeae PH-1]
(486 aa)

Score: 532 bits (1371), Expect: 6.42555e-150
Length: 369, Idn/Pos/Gap = 274/315/2 (74%/85%/0%)

Query:  29 LSTDSWPLLLKNYDRLNVRTTHYTPIPDAGYSPLKRPIQEYIRSGVINLDKPANPSSHEV  88
           L T  WPLLLKNY++L  RT H+TPIP+ G SPLKR +++YI SGVINLDKP+NPSSHEV
Sbjct:  27 LDTSQWPLLLKNYEKLLTRTGHFTPIPN-GCSPLKRDLKQYISSGVINLDKPSNPSSHEV  85

Query:  89 VAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAGKEYVAVLRLHGMRPE 148
           VAW+KRILR EKTGHSGTLDP+VTGCLIVCI+RATRLVKSQQ AGKEYVAV+RLH   P 
Sbjct:  86 VAWVKRILRCEKTGHSGTLDPKVTGCLIVCIDRATRLVKSQQGAGKEYVAVIRLHDKLPG 145

Query: 149 LDEATVRRAIETLTGPLYQRPPLISAVKRQLRIRTIYESKLLEYDPKRRLVLFWVSCEAG 208
             +A   RA+ETLTG L+QRPPLISAVKRQLRIRTI+ESKL+E+D  R L +FWVSCEAG
Sbjct: 146 -GQAQFARALETLTGALFQRPPLISAVKRQLRIRTIHESKLIEFDNDRHLGVFWVSCEAG 204

Query: 209 TYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLR 268
           TYIRTLCVHLGLLLGVGGHMQELRRVRSG   E  G+VT+HDVLDAQW  D T+DESYLR
Sbjct: 205 TYIRTLCVHLGLLLGVGGHMQELRRVRSGAMDESKGLVTLHDVLDAQWQMDNTRDESYLR 264

Query: 269 RVIKPLESLLVHHKRIVIKDSCVNAVCYGAKLMLPGVLRYENDIECGEEVVIMTTKGEAV 328
           +VI PLE+LL  +KR+V+KDS VNAVCYGAKLMLPG+LRYE  IE  EEVV+MTTKGEA+
Sbjct: 265 KVISPLETLLTSYKRLVVKDSAVNAVCYGAKLMLPGLLRYEAAIEHHEEVVLMTTKGEAI 324

Query: 329 ALAIAHMSTSEIASCDHGVVARIKRVVMERDLYPRRWGLGPVASRKKAMIQRGELDKHGR 388
           AL IA MST E+++CDHGVVA++KR +MERDLYPRRWGLGPVA  KK +   G+LDK+GR
Sbjct: 325 ALGIAQMSTVEMSTCDHGVVAKVKRCIMERDLYPRRWGLGPVALEKKKLKADGKLDKYGR 384

Query: 389 PNEHTPSDW 397
           PN+ TP+ W
Sbjct: 385 PNDATPAKW 393

emb|CAB86704.1| probable dyskerin [Leishmania major]
(430 aa)

Score: 525 bits (1351), Expect: 1.20209e-147
Length: 392, Idn/Pos/Gap = 249/320/8 (63%/81%/2%)

Query:   9 LAEQQRSLSFQIPS---DAGENGLSTDSWPLLLKNYDRLNVRTTHYTPIPDAGYSPLKRP  65
           + E QRS  F IP+   DA  + L  + WPLLLKNYD++NVR+TH+T + + G+SPL+RP
Sbjct:   6 VGEIQRSEDFCIPAGDRDA-NSALPAEEWPLLLKNYDKMNVRSTHFTLL-ECGWSPLRRP  63

Query:  66 IQEYIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRL 125
           + EYI+ G+IN+DKP+NPSSHEVV+WIKRIL+ +KTGH+GTLDP+VTG LI+C +RATRL
Sbjct:  64 LAEYIKYGMINMDKPSNPSSHEVVSWIKRILKCDKTGHAGTLDPKVTGALIICTDRATRL 123

Query: 126 VKSQQSAGKEYVAVLRLHGMRPELDEATVRRAIETLTGPLYQRPPLISAVKRQLRIRTIY 185
           VKSQQ+AGK Y+ VLRLH     + +  V  A++ LTGP +QRPPLI+AVKRQLRIR IY
Sbjct: 124 VKSQQNAGKTYIGVLRLHDT---VSQKKVDAALQRLTGPCFQRPPLIAAVKRQLRIRNIY 180

Query: 186 ESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGM 245
            ++L+EYD  R L +F   CEAGTYIRTLCVH+GL+LG GGHM+ELRR+R+GV +E D +
Sbjct: 181 SNQLIEYDKHRHLAVFETHCEAGTYIRTLCVHVGLILGAGGHMEELRRIRTGVITENDHL 240

Query: 246 VTMHDVLDAQWLFDTTKDESYLRRVIKPLESLLVHHKRIVIKDSCVNAVCYGAKLMLPGV 305
            TMHDV+DAQWL++  KD++YLRRVI P E LL +HKRIV+KDS VNAVCYGAKLM+PG+
Sbjct: 241 STMHDVMDAQWLYENEKDDTYLRRVILPCEYLLSNHKRIVVKDSAVNAVCYGAKLMIPGL 300

Query: 306 LRYENDIECGEEVVIMTTKGEAVALAIAHMSTSEIASCDHGVVARIKRVVMERDLYPRRW 365
            R++N IE  + VV+MTTKGEA+ALA A M+TS++AS DHG+VAR KRV+M+RD YPRRW
Sbjct: 301 ARFDNGIERDDVVVLMTTKGEAIALAYAEMTTSQMASVDHGIVARSKRVIMDRDTYPRRW 360

Query: 366 GLGPVASRKKAMIQRGELDKHGRPNEHTPSDW 397
           GLGP+A +K++M++ G LDK+GRP  +TPSDW
Sbjct: 361 GLGPIAVKKRSMMKDGLLDKYGRPQSNTPSDW 392

ref|NP_702062.1| hypothetical protein PF14_0174 [Plasmodium falciparum 3D7]
gb|AAN36786.1| hypothetical protein, conserved [Plasmodium falciparum 3D7]
(466 aa)

Score: 520 bits (1338), Expect: 4.72432e-146
Length: 386, Idn/Pos/Gap = 235/305/3 (60%/79%/0%)

Query:  12 QQRSLSFQIPSDAGENGLSTDSWPLLLKNYDRLNVRTTHYTPIPDAGYSPLKRPIQEYIR  71
           +++ + ++I  +  E  + T +WPLLLKNYD+LN+RT+H+TP+P  G SP  R I+EY++
Sbjct:   2 EEKKMDYKIEPERKEAAIDTSNWPLLLKNYDKLNIRTSHFTPLP-MGNSPYSRNIEEYLK  60

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
            G+INLDKP+NPSSHEVV+WI++ILR EKTGHSGTLDP+VTG L+VC+ RATRLVKSQQ 
Sbjct:  61 YGIINLDKPSNPSSHEVVSWIRKILRCEKTGHSGTLDPKVTGVLLVCLNRATRLVKSQQE 120

Query: 132 AGKEYVAVLRLHGMRPELDEATVRRAIETLTGPLYQRPPLISAVKRQLRIRTIYESKLLE 191
           +GKEYV V + H     ++E  V+  +    G ++QRPPLI AVKRQLR+RTIY+SKLL+
Sbjct: 121 SGKEYVCVCKFHSKPKSIEE--VKLVLNNFQGAIFQRPPLICAVKRQLRVRTIYDSKLLD 178

Query: 192 YDPKRRLVLFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDV 251
           YD    + +FWV C+AGTYIRTLC H+GLLLGVG HMQELRRV+SG  +EYD M T+HD+
Sbjct: 179 YDETNNVCVFWVKCQAGTYIRTLCEHIGLLLGVGAHMQELRRVKSGNMTEYDNMCTLHDI 238

Query: 252 LDAQWLFDTTKDESYLRRVIKPLESLLVHHKRIVIKDSCVNAVCYGAKLMLPGVLRYEND 311
           LDAQ+++DTT DESYLR++I PLE LL++  RIVIKDS VNA+CYGAKL +PGVLR++N+
Sbjct: 239 LDAQYIYDTTGDESYLRKIITPLEKLLINFPRIVIKDSAVNAICYGAKLTIPGVLRFDNN 298

Query: 312 IECGEEVVIMTTKGEAVALAIAHMSTSEIASCDHGVVARIKRVVMERDLYPRRWGLGPVA 371
           I+   E+VIMTTKGEAVALAIA M+++ IA+ DHGVV+  KRV+M+RD Y  +WG G  +
Sbjct: 299 IDVNTEIVIMTTKGEAVALAIAQMTSTVIATVDHGVVSLTKRVIMDRDTYDVKWGFGNRS 358

Query: 372 SRKKAMIQRGELDKHGRPNEHTPSDW 397
             KK +I  G LDK+G+PNE TP  W
Sbjct: 359 MEKKKLILAGLLDKYGKPNEKTPLSW 384

gb|EAA17472.1| unknown protein-related [Plasmodium yoelii yoelii]
(4236 aa)

Score: 519 bits (1336), Expect: 6.87706e-146
Length: 382, Idn/Pos/Gap = 232/301/3 (60%/78%/0%)

Query:   16 LSFQIPSDAGENGLSTDSWPLLLKNYDRLNVRTTHYTPIPDAGYSPLKRPIQEYIRSGVI   75
            L ++I  +  E  +   +WPLLLKNYD+LN+R++H+TP+P  G SP  R ++EY++ G+I
Sbjct: 3782 LEYKIEPEKKEATIDASNWPLLLKNYDKLNIRSSHFTPLP-MGNSPYSRNLKEYLKYGII 3840

Query:   76 NLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAGKE  135
            NLDKP+NPSSHEVV+WI++ILR EKTGHSGTLDP+VTG L+VC+ RATRLVKSQQ +GKE
Sbjct: 3841 NLDKPSNPSSHEVVSWIRKILRCEKTGHSGTLDPKVTGVLLVCLNRATRLVKSQQESGKE 3900

Query:  136 YVAVLRLHGMRPELDEATVRRAIETLTGPLYQRPPLISAVKRQLRIRTIYESKLLEYDPK  195
            YV V + H     ++E  V+  +    G ++QRPPLI AVKRQLR+RTIYESKLL+YD  
Sbjct: 3901 YVCVCKFHSKPKSIEE--VKLVLNNFQGAIFQRPPLICAVKRQLRVRTIYESKLLDYDDT 3958

Query:  196 RRLVLFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQ  255
              L +FWV C+AGTYIRTLC H+GLLLGVG HMQELRRV+SG  +EYD M T+HD++DAQ
Sbjct: 3959 NNLCVFWVRCQAGTYIRTLCEHIGLLLGVGAHMQELRRVKSGNMTEYDNMCTLHDIMDAQ 4018

Query:  256 WLFDTTKDESYLRRVIKPLESLLVHHKRIVIKDSCVNAVCYGAKLMLPGVLRYENDIECG  315
            +++DTT DE+YLR++I PLE LL++  RIVIKDS VNA+CYGAKL +PGVLR++N+I+  
Sbjct: 4019 YIYDTTGDETYLRKIITPLEKLLINFPRIVIKDSAVNAICYGAKLTIPGVLRFDNNIDVY 4078

Query:  316 EEVVIMTTKGEAVALAIAHMSTSEIASCDHGVVARIKRVVMERDLYPRRWGLGPVASRKK  375
             E+V+MTTKGEAVALAIA M+++ IA+ DHG+VA  KRV+M+RD Y  +WG G  +  KK
Sbjct: 4079 SEIVLMTTKGEAVALAIAQMTSTVIATVDHGIVALTKRVIMDRDTYDVKWGFGNRSMEKK 4138

Query:  376 AMIQRGELDKHGRPNEHTPSDW  397
             +I  G LDK+G+PNE TP  W
Sbjct: 4139 KLILAGLLDKYGKPNEKTPISW 4160

ref|XP_549382.1| PREDICTED: similar to Dyskerin (Nucleolar protein NAP57) (CBF5 homolog) [Canis familiaris]
(737 aa)

Score: 510 bits (1314), Expect: 2.93879e-143
Length: 448, Idn/Pos/Gap = 277/328/63 (61%/73%/14%)

Query:   9 LAEQQRSLSFQIPSDAGENGLSTDSWPLLLKNYDRLNVRTTHYTPIPDAGYSPLKRPIQE  68
           +AE Q +  F I  ++    L T  WPLLLKN+D+LNVRTTHYTP+P  G +PLKR I +
Sbjct: 165 VAEIQHAEEFLIKPESKVAQLDTSQWPLLLKNFDKLNVRTTHYTPLP-CGSNPLKREIGD 223

Query:  69 YIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKS 128
           YIR+G INLDKP+NPSSHEVVAWI+RILRVEKTGHSGTLDP+VTGCLIVCIERATRLVKS
Sbjct: 224 YIRTGFINLDKPSNPSSHEVVAWIRRILRVEKTGHSGTLDPKVTGCLIVCIERATRLVKS 283

Query: 129 QQSAGKEYVAVLRLHGMRPELDEAT-VRRAIETLTGPLYQRPPLISAVKRQLRIRTIYES 187
           QQSAGKEYV ++RLH     ++  T + RA+ETLTG L+QRPPLI+AVKRQLR+RTIYES
Sbjct: 284 QQSAGKEYVGIVRLHN---AIEGGTQLSRALETLTGALFQRPPLIAAVKRQLRVRTIYES 340

Query: 188 KLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVT 247
           K++EYDP+RRL +FWVSCEAGTYIRTLCVHLGLLLGVGG MQELRRVRSGV SE D MVT
Sbjct: 341 KMIEYDPERRLGIFWVSCEAGTYIRTLCVHLGLLLGVGGQMQELRRVRSGVMSEKDHMVT 400

Query: 248 MHDVLDAQWLFDTTKDESYLRRVIKPLESLLVHHKRIVIKDSCVNAVCYGAKLMLPGVLR 307
           MHDVLDAQWL+D  KDESYLRRV+ PLE LL  HKR+V+KDS VNA+CYGAK+MLPGVLR
Sbjct: 401 MHDVLDAQWLYDNHKDESYLRRVVYPLEKLLTSHKRLVMKDSAVNAICYGAKIMLPGVLR 460

Query: 308 YENDIECGE---------EVVIMTTKGEAVAL---------------------------- 330
           YE+ IE  E         E + M   G+  A+                            
Sbjct: 461 YEDGIEVNEEIVVITTKGEAICMGCLGQVRAVKAKDRSRDPDEEEVDGSSLVPLAAIRGH 520

Query: 331 ---------------------AIAHMSTSEIASCDHGVVARIKRVVMERDLYPRRWGLGP 369
                                AIA M+T+ I++CDHG+VA+IKRV+MERD YPR+WGLGP
Sbjct: 521 VLAAWLQRRGGRSSMRGISIYAIALMTTAVISTCDHGIVAKIKRVIMERDTYPRKWGLGP 580

Query: 370 VASRKKAMIQRGELDKHGRPNEHTPSDW 397
            AS+K+ MI++G LDKHG+P + TP+ W
Sbjct: 581 KASQKRLMIKQGLLDKHGKPTDSTPATW 608

emb|CAH99624.1| conserved hypothetical protein [Plasmodium berghei]
(456 aa)

Score: 510 bits (1313), Expect: 3.38665e-143
Length: 382, Idn/Pos/Gap = 231/301/3 (60%/78%/0%)

Query:  16 LSFQIPSDAGENGLSTDSWPLLLKNYDRLNVRTTHYTPIPDAGYSPLKRPIQEYIRSGVI  75
           + ++I  +  E  +   +WPLLLKNYD+LN+R++H+TP+P  G SP  R ++EY++ G+I
Sbjct:   4 VEYKIEPEKKEATIDASNWPLLLKNYDKLNIRSSHFTPLP-MGNSPYSRNLKEYLKYGII  62

Query:  76 NLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAGKE 135
           NLDKP+NPSSHEVV+WI++ILR EKTGHSGTLDP+VTG L+VC+ RATRLVKSQQ +GKE
Sbjct:  63 NLDKPSNPSSHEVVSWIRKILRCEKTGHSGTLDPKVTGVLLVCLNRATRLVKSQQESGKE 122

Query: 136 YVAVLRLHGMRPELDEATVRRAIETLTGPLYQRPPLISAVKRQLRIRTIYESKLLEYDPK 195
           YV V + H     ++E  V+  +    G ++QRPPLI AVKRQLR+RTIYESKLL+YD  
Sbjct: 123 YVCVCKFHSKPKSIEE--VKLVLNNFQGAIFQRPPLICAVKRQLRVRTIYESKLLDYDDT 180

Query: 196 RRLVLFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQ 255
             L +FWV C+AGTYIRTLC H+GLLLGVG HMQELRRV+SG  +EYD M T+HD++DAQ
Sbjct: 181 NNLCVFWVRCQAGTYIRTLCEHIGLLLGVGAHMQELRRVKSGNMTEYDNMCTLHDIMDAQ 240

Query: 256 WLFDTTKDESYLRRVIKPLESLLVHHKRIVIKDSCVNAVCYGAKLMLPGVLRYENDIECG 315
           +++DTT DE+YLR++I PLE LL++  RIVIKDS VNA+CYGAKL +PGVLR++N+I+  
Sbjct: 241 YIYDTTGDETYLRKIITPLEKLLINFPRIVIKDSAVNAICYGAKLTIPGVLRFDNNIDVY 300

Query: 316 EEVVIMTTKGEAVALAIAHMSTSEIASCDHGVVARIKRVVMERDLYPRRWGLGPVASRKK 375
            E+V+MTTKGEAVALAIA M+++ IA+ DHG+VA  KRV+M+RD Y  +WG G  +  KK
Sbjct: 301 SEIVLMTTKGEAVALAIAQMTSTVIATVDHGIVALTKRVIMDRDTYDVKWGFGNRSMEKK 360

Query: 376 AMIQRGELDKHGRPNEHTPSDW 397
            +I  G LDK+G+PNE TP  W
Sbjct: 361 KLILAGLLDKYGKPNEKTPISW 382

gb|EAL44603.1| centromere/microtubule binding protein cbf5, putative [Entamoeba histolytica HM-1:IMSS]
(484 aa)

Score: 493 bits (1270), Expect: 3.36339e-138
Length: 374, Idn/Pos/Gap = 232/298/3 (62%/79%/0%)

Query:  33 SWPLLLKNYDRLNVRTTHYTPIPDAGYSPLKRPIQEYIRSGVINLDKPANPSSHEVVAWI  92
           SWPLLL+N+D+L ++T HYTP   AG SP+ RPI E+ + G+INLDKPANPSSHEVVAW+
Sbjct:  19 SWPLLLQNFDQLEIKTGHYTP-ASAGNSPINRPISEHFKYGIINLDKPANPSSHEVVAWL  77

Query:  93 KRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAGKEYVAVLRLHGMRPELDEA 152
           KRIL+VEKTGHSGTLDP VTGCLIVCI+RATRLVKSQQ AGKEYV + + H      DE 
Sbjct:  78 KRILKVEKTGHSGTLDPAVTGCLIVCIDRATRLVKSQQDAGKEYVCICKFH--EAISDEQ 135

Query: 153 TVRRAIETLTGPLYQRPPLISAVKRQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIR 212
            V+  I TLTG L+Q PP+I+AVKR LRIRTIY ++LLE D K  L LF   C+AGTY+R
Sbjct: 136 QVKTVINTLTGALFQLPPVIAAVKRSLRIRTIYNTELLEVDKKEGLALFRTQCQAGTYMR 195

Query: 213 TLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIK 272
           TLCVHLG L+G G HM+ELRRVRSG  +E D MVT+HDVLDA +L++   DESY+R  ++
Sbjct: 196 TLCVHLGYLMGCGAHMEELRRVRSGNLTEKDNMVTLHDVLDAMYLYENHGDESYIRHCVR 255

Query: 273 PLESLLVHHKRIVIKDSCVNAVCYGAKLMLPGVLRYENDIECGEEVVIMTTKGEAVALAI 332
           PLE+LL  +K+IV+KDS VNA+CYGAKLM+PG+LRY   I   E VV+MT+KGEA+AL I
Sbjct: 256 PLETLLTKYKKIVVKDSSVNAICYGAKLMVPGLLRYSKGITMNEIVVLMTSKGEAIALGI 315

Query: 333 AHMSTSEIASCDHGVVARIKRVVMERDLYPRRWGLGPVASRKKAMIQRGELDKHGRPNEH 392
           A M++ E+ +C++GVVA IKRV+M++DLYPR+WGLGP A +KK ++  G+L+K+G+PN+ 
Sbjct: 316 AKMTSEEMITCEYGVVATIKRVIMDKDLYPRKWGLGPHAQQKKKLVAEGKLEKYGKPNDK 375

Query: 393 TPSDWRRVQPELES 406
           TP+++ +  P ++S
Sbjct: 376 TPAEYLKEVPYIKS 389

gb|AAW27741.1| unknown [Schistosoma japonicum]
(459 aa)

Score: 485 bits (1248), Expect: 1.10049e-135
Length: 396, Idn/Pos/Gap = 249/309/7 (62%/78%/1%)

Query:  20 IPSDAGENGLSTDSWPLLLKNYDRLNVRTTHYTPIPDAGYSPLKRPIQEYIRSGVINLDK  79
           IP D     L    WPLLLKN   +NVR  H+      G+SPL RP+ EYI+SGVINLDK
Sbjct:  27 IPEDKKPT-LDCSQWPLLLKNVHLMNVRECHFEA-DTTGFSPLHRPLDEYIKSGVINLDK  84

Query:  80 PANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAGKEYVAV 139
           P NPSSHEVVAW+KR L V KTGHSGTLDP+V+GCLIVCI+RATRLVKSQQSAGKEYV +
Sbjct:  85 PCNPSSHEVVAWVKRALGVNKTGHSGTLDPKVSGCLIVCIDRATRLVKSQQSAGKEYVCI 144

Query: 140 LRLHGMRPELDEATVRRAIETLTGPLYQRPPLISAVKRQLRIRTIYESKLLEYDPKRRLV 199
            RLH    ++ +  +++A+E LTG L+QRPPL++AVKRQLR+RTIYESKLLEYD  R L 
Sbjct: 145 FRLHDSVDDVKK--IQKAVEGLTGALFQRPPLVAAVKRQLRVRTIYESKLLEYDKSRNLG 202

Query: 200 LFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFD 259
           L  V CEAGTY+RTLCVHLGLLLG GG M+ELRR R+G  SE D +VTMHD+LDA+WL+D
Sbjct: 203 LITVRCEAGTYVRTLCVHLGLLLGCGGVMEELRRSRTGFMSERDNLVTMHDILDAKWLYD 262

Query: 260 TTKDESYLRRVIKPLESLLVHHKRIVIKDSCVNAVCYGAKLMLPGVLRYENDIECGEEVV 319
             +DE+YLRRV+ PLE LLV HKRI++KD+ V A+C+GAKLMLPGVLRY+NDI   +E+V
Sbjct: 263 NRRDETYLRRVVMPLERLLVKHKRIMLKDTAVCAICFGAKLMLPGVLRYDNDINVNDEIV 322

Query: 320 IMTTKGEAVALAIAHMSTSEIASCDHGVVARIKRVVMERDLYPRRWGLGPVASRKKAMIQ 379
           +MTTKGEAVALAIA M+T+ IA+CDHG+VA++KRV+MERDLYPR+WG GPVA  +K ++ 
Sbjct: 323 LMTTKGEAVALAIALMTTATIATCDHGLVAKLKRVIMERDLYPRQWGRGPVAMERKKLVA 382

Query: 380 RGELDKHGRPN--EHTPSDWRRVQPELESAPSRMER 413
           +G L K  +    E TP+    ++ E+E+  S + +
Sbjct: 383 QGLLKKFAKSGEIESTPNS-AGLRKEVEAVKSSVAK 417

ref|XP_397244.1| similar to CG3333-PA [Apis mellifera]
(357 aa)

Score: 460 bits (1184), Expect: 2.9516e-128
Length: 313, Idn/Pos/Gap = 216/265/2 (69%/84%/0%)

Query:  85 SHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAGKEYVAVLRLHG 144
           +  VVAWIKRIL+VEKTGHSGTLDP+V+GCLIVCI+RATRL KSQQSAGKEY+AV +LH 
Sbjct:   2 AESVVAWIKRILKVEKTGHSGTLDPKVSGCLIVCIDRATRLAKSQQSAGKEYIAVFKLHS  61

Query: 145 MRPELDEATVRRAIETLTGPLYQRPPLISAVKRQLRIRTIYESKLLEYDPKRRLVLFWVS 204
               L +  V +A+E L G L+QRPPLISAVKRQLR+RT+Y+S  L+YD +R + +F VS
Sbjct:  62 APESLQK--VSQALEKLRGALFQRPPLISAVKRQLRVRTVYDSWFLDYDEERNMGVFRVS 119

Query: 205 CEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDE 264
           CEAG+YIRT+CVHLGL LG G  MQELRR RSGV SE DGMVTMHD+LDAQWL++   DE
Sbjct: 120 CEAGSYIRTICVHLGLFLGTGCQMQELRRNRSGVQSENDGMVTMHDILDAQWLYENHGDE 179

Query: 265 SYLRRVIKPLESLLVHHKRIVIKDSCVNAVCYGAKLMLPGVLRYENDIECGEEVVIMTTK 324
           SYLRRVIKPLE+LL++HKRI++KDS VNA+CYGAK+MLPG+L Y++ IE  +E+VI+TTK
Sbjct: 180 SYLRRVIKPLEALLINHKRIIVKDSAVNAICYGAKIMLPGILMYDDGIELNQEIVIVTTK 239

Query: 325 GEAVALAIAHMSTSEIASCDHGVVARIKRVVMERDLYPRRWGLGPVASRKKAMIQRGELD 384
           GEA+ALAIA M++  + +CDHGV A+IKRV+MERD YPR+WGLGP AS KK MI  G+LD
Sbjct: 240 GEAIALAIALMTSPTMTTCDHGVAAKIKRVIMERDAYPRKWGLGPKASIKKRMIIEGKLD 299

Query: 385 KHGRPNEHTPSDW 397
           K+G+PNE+TP+DW
Sbjct: 300 KYGKPNENTPADW 312

emb|CAD26622.1| CENTROMERE/MICROTUBULE BINDING PROTEIN [Encephalitozoon cuniculi GB-M1]
ref|NP_597445.1| CENTROMERE/MICROTUBULE BINDING PROTEIN [Encephalitozoon cuniculi GB-M1]
(357 aa)

Score: 422 bits (1085), Expect: 1.01799e-116
Length: 343, Idn/Pos/Gap = 211/262/7 (61%/76%/2%)

Query:  25 GENGLSTDSWPLLLKNYDRLNVRTTHYTPIPDAGYSPLKRPIQEYIRSGVINLDKPANPS  84
           GE+G     W LLL N DR+ VRT HYTP+   G  PL+R I+EYI+ G+IN+DK  NPS
Sbjct:  13 GEDGEGV--WDLLLANMDRMVVRTGHYTPL-GCGSMPLRRRIEEYIKYGIINVDKSPNPS  69

Query:  85 SHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAGKEYVAVLRLHG 144
           SHEVV W+K IL+ EKTGHSGTLDPQV+G L +CI+RATRL KSQQS GKEYV V+    
Sbjct:  70 SHEVVTWVKEILKCEKTGHSGTLDPQVSGVLTICIDRATRLTKSQQSLGKEYVCVIEF-- 127

Query: 145 MRPELDEATVRRAIETLTGPLYQRPPLISAVKRQLRIRTIYESKLLEYDPKRRLVLFWVS 204
              E DE    +A + L G L+QRPPL+ AVKR+LRIR +Y   +LE++ ++RL LF VS
Sbjct: 128 -LSEPDEEGFHKASKRLVGSLFQRPPLMCAVKRELRIRNVYSIDILEFNREKRLGLFKVS 186

Query: 205 CEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDE 264
           CEAGTY+RTLC H+G+L+G G  M+ELRR RSG  SE D   T+HD+LDA ++F+TTKDE
Sbjct: 187 CEAGTYVRTLCTHIGILMGCGARMKELRRTRSGRISEKDAF-TLHDLLDAVYIFNTTKDE 245

Query: 265 SYLRRVIKPLESLLVHHKRIVIKDSCVNAVCYGAKLMLPGVLRYENDIECGEEVVIMTTK 324
           + +RRVI PLESLLV + RI+IKDSCVNA+CYGAKL + GVLR++ DI+ G EVVIMTTK
Sbjct: 246 TVIRRVILPLESLLVGYPRIMIKDSCVNAICYGAKLSITGVLRFDRDIDVGTEVVIMTTK 305

Query: 325 GEAVALAIAHMSTSEIASCDHGVVARIKRVVMERDLYPRRWGL 367
           GEAVAL IA +S+ E++  DHG+V R KRV+ME+DLYPR WG 
Sbjct: 306 GEAVALGIALVSSPEMSIIDHGLVCRTKRVIMEKDLYPRSWGF 348

gb|EAA37462.1| GLP_576_9913_8648 [Giardia lamblia ATCC 50803]
(421 aa)

Score: 406 bits (1044), Expect: 6.17949e-112
Length: 375, Idn/Pos/Gap = 207/269/9 (55%/71%/2%)

Query:  31 TDSWPLLLKNYDRLNVRTTHYTPIPDAGYSPLKRPIQEYIRSGVINLDKPANPSSHEVVA  90
           T  + LLL+ +++L+VR+  YTP  + GYSPL+RPI+E+++ GVINLDK A PSSHEVVA
Sbjct:   9 TSEFKLLLEGFNQLHVRSASYTPTQN-GYSPLQRPIREHLKYGVINLDKTAGPSSHEVVA  67

Query:  91 WIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAGKEYVAVLRLHGMRPELD 150
           WI+RIL VEKTGHSGTLDP VTGCL+VC++RATRLVKSQQ  GKEYV VL+   +    D
Sbjct:  68 WIRRILEVEKTGHSGTLDPGVTGCLLVCLDRATRLVKSQQLMGKEYVCVLQFKDLAALKD 127

Query: 151 E-------ATVRRAIETLTGPLYQRPPLIS-AVKRQLRIRTIYESKLLEYDPKRRLVLFW 202
           E       A +++A+ TL     Q PP    AVKRQLR+R IY   LLE++ K    +  
Sbjct: 128 EDARKAFSACLQQALATLRCAQLQLPPKEGCAVKRQLRVREIYTLDLLEFNFKTGQAVLR 187

Query: 203 VSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTK 262
            SC+AGTY+RTLCVH+GLL+G   +M ELRRVRSG  +E   MVT+HDVLD+ W +    
Sbjct: 188 ASCQAGTYMRTLCVHIGLLVGHEAYMLELRRVRSGELTEKTNMVTLHDVLDSFWCWKNLG 247

Query: 263 DESYLRRVIKPLESLLVHHKRIVIKDSCVNAVCYGAKLMLPGVLRYENDIECGEEVVIMT 322
           DESYLR+V+ PLE LL  +KRI +KDS +NA+ YGA L + GVLRY+  I  G+ VV+++
Sbjct: 248 DESYLRKVVMPLEYLLKSYKRIFVKDSSINALTYGAPLHIQGVLRYDPRISIGDTVVLVS 307

Query: 323 TKGEAVALAIAHMSTSEIASCDHGVVARIKRVVMERDLYPRRWGLGPVASRKKAMIQRGE 382
           TKGEAVAL  A M   +I     G+V+++KRV+M+RDLY R+WGLGP A  KK +I+ G+
Sbjct: 308 TKGEAVALGTATMGAQDIMGVSRGIVSKVKRVIMDRDLYDRQWGLGPTALLKKQLIKNGQ 367

Query: 383 LDKHGRPNEHTPSDW 397
           LDK+G  N+ TP +W
Sbjct: 368 LDKYGGINKDTPKEW 382

ref|XP_521345.1| PREDICTED: similar to Dyskerin (Nucleolar protein NAP57) (CBF5 homolog) [Pan troglodytes]
(382 aa)

Score: 385 bits (990), Expect: 1.03842e-105
Length: 277, Idn/Pos/Gap = 205/234/5 (74%/84%/1%)

Query:   9 LAEQQRSLSFQIPSDAGENGLSTDSWPLLLKNYDRLNVRTTHYTPIPDAGYSPLKRPIQE  68
           +AE Q +  F I  ++    L T  WPLLLKN+D+LNVRTTHYTP+   G +PLKR I +
Sbjct: 108 VAEIQHAEEFLIKPESKVAKLDTSQWPLLLKNFDKLNVRTTHYTPLA-CGSNPLKREIGD 166

Query:  69 YIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKS 128
           YIR+G INLDKP+NPSSHEVVAWI+RILRVEKTGHSGTLDP+VTGCLIVCIERATRLVKS
Sbjct: 167 YIRTGFINLDKPSNPSSHEVVAWIRRILRVEKTGHSGTLDPKVTGCLIVCIERATRLVKS 226

Query: 129 QQSAGKEYVAVLRLHGMRPELDEAT-VRRAIETLTGPLYQRPPLISAVKRQLRIRTIYES 187
           QQSAGKEYV ++RLH     ++  T + RA+ETLTG L+QRPPLI+AVKRQLR+RTIYES
Sbjct: 227 QQSAGKEYVGIVRLHN---AIEGGTQLSRALETLTGALFQRPPLIAAVKRQLRVRTIYES 283

Query: 188 KLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVT 247
           K++EYDP+RRL +FWVSCEAGTYIRTLCVHLGLLLGVGG MQELRRVRSGV SE D MVT
Sbjct: 284 KMIEYDPERRLGIFWVSCEAGTYIRTLCVHLGLLLGVGGQMQELRRVRSGVMSEKDHMVT 343

Query: 248 MHDVLDAQWLFDTTKDESYLRRVIKPLESLLVHHKRI 284
           MHDVLDAQWL+D  KDESYLRRV+ PLE LL  HKR+
Sbjct: 344 MHDVLDAQWLYDNHKDESYLRRVVYPLEKLLTSHKRL 380

emb|CAF89617.1| unnamed protein product [Tetraodon nigroviridis]
(285 aa)

Score: 365 bits (938), Expect: 1.11204e-99
Length: 262, Idn/Pos/Gap = 184/218/10 (70%/83%/3%)

Query: 147 PELDEA---TVRRAIETLTGPLYQRPPLISAVKRQLRIRTIYESKLLEYDPKRRLVLFWV 203
           P LD +    + +A+E LTG L+QRPPLI+AVKRQLR+RTIYESKL+EYDP+RR  +FWV
Sbjct:  17 PSLDTSHWPLLLKALEMLTGALFQRPPLIAAVKRQLRVRTIYESKLIEYDPERRFGIFWV  76

Query: 204 SCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKD 263
           SCEAGTYIRTLCVHLGLLLGVGG MQELRRVRSGV  E D MVTMHDVLDAQW FD  KD
Sbjct:  77 SCEAGTYIRTLCVHLGLLLGVGGQMQELRRVRSGVLGEKDNMVTMHDVLDAQWQFDHNKD 136

Query: 264 ESYLRRVIKPLESLLVHHKRIVIKDSC-------VNAVCYGAKLMLPGVLRYENDIECGE 316
           ESYLRRVI PLE LLV HKR+V+KDS        VNA+CYGAK+MLPGVLRYE+ IE  +
Sbjct: 137 ESYLRRVIFPLEKLLVSHKRLVMKDSAVSLFVTLVNAICYGAKIMLPGVLRYEDGIELNQ 196

Query: 317 EVVIMTTKGEAVALAIAHMSTSEIASCDHGVVARIKRVVMERDLYPRRWGLGPVASRKKA 376
           ++V++TTKGEA+  A+A M+T+ I++CDHGVVA+IKRV+MERD YPR+WGLGP AS+KK 
Sbjct: 197 DIVVITTKGEAICTAVALMTTAVISTCDHGVVAKIKRVIMERDTYPRKWGLGPKASQKKM 256

Query: 377 MIQRGELDKHGRPNEHTPSDWR 398
           MIQ+G LDKHG+ N  TP+DW+
Sbjct: 257 MIQKGLLDKHGKANSSTPADWK 278

emb|CAB49444.1| truB tRNA pseudouridine synthase II [Pyrococcus abyssi GE5]
sp|Q9V1A5|TRUB_PYRAB Probable tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
ref|NP_126213.1| probable trna pseudouridine synthase b (trna pseudouridine 55 synthase) (psi55 synthase) (pseudouridylate synthase) (uracil hydrolyase) [Pyrococcus abyssi GE5]
(334 aa)

Score: 291 bits (744), Expect: 2.94599e-77
Length: 311, Idn/Pos/Gap = 158/207/5 (50%/66%/1%)

Query:  55 PDAGYSPLKRPIQEYIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGC 114
           P  G+ P KRPI+ +I+ GVINLDKP  P+SHEVVAWIKRIL +EK GH GTLDP+V+G 
Sbjct:  29 PKWGFPPDKRPIELHIQYGVINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDPKVSGV  88

Query: 115 LIVCIERATRLVKSQQSAGKEYVAVLRLHGMRPELDEATVRRAIETLTGPLYQRPPLISA 174
           L V +ERATR+V++   AGKEYVA++ LHG  PE     +R  ++   G + QRPPL SA
Sbjct:  89 LPVALERATRVVQALLPAGKEYVALMHLHGDVPE---DKIRAVMKEFEGEIIQRPPLRSA 145

Query: 175 VKRQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRV 234
           VKR+LR R +Y  ++LE D   R VLF V  EAGTYIR+L  H+GL LGVG HM ELRR 
Sbjct: 146 VKRRLRTRKVYYIEILEIDG--RDVLFRVGVEAGTYIRSLIHHIGLALGVGAHMAELRRT 203

Query: 235 RSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPLESLLVHHKRIVIKDSCVNAV 294
           RSG   E + +VT+HD++D    +     E Y+R+ I+P+E  + H  +I IKDS V AV
Sbjct: 204 RSGPFKEDETLVTLHDLVDYYHFWKEDGIEEYIRKAIQPMEKAVEHLPKIWIKDSAVAAV 263

Query: 295 CYGAKLMLPGVLRYENDIECGEEVVIMTTKGEAVALAIAHMSTSEIASCDHGVVARIKRV 354
            +GA L +PG+++    I+ G+ V IMT K E VAL  A MST E+     G+   +++V
Sbjct: 264 AHGANLTVPGIVKLNAGIKKGDLVAIMTLKDELVALGKAMMSTQEMIERSKGIAVDVEKV 323

Query: 355 VMERDLYPRRW 365
            M RD YP+ W
Sbjct: 324 FMPRDWYPKLW 334

ref|ZP_00295651.1| COG0130: Pseudouridine synthase [Methanosarcina barkeri str. fusaro]
(338 aa)

Score: 290 bits (742), Expect: 5.98744e-77
Length: 324, Idn/Pos/Gap = 154/213/6 (47%/65%/1%)

Query:  42 DRLNVRTTHYTPIPDAGYSPLKRPIQEYIRSGVINLDKPANPSSHEVVAWIKRILRVEKT 101
           +R+ VR +     P  G  P KRPI EYI  GV+N+DKP  P+SHEV AW+K IL V   
Sbjct:  12 ERILVRKSGAWTNPSYGSYPEKRPILEYIEKGVVNIDKPKGPTSHEVAAWVKAILGVSTA  71

Query: 102 GHSGTLDPQVTGCLIVCIERATRLVKSQQSAGKEYVAVLRLHGMRPELDEATVRRAIETL 161
           GH+G+LDP+VTG L   + +AT+ V + + +GKEYV +L+LH    E+ +  VR+  E  
Sbjct:  72 GHAGSLDPKVTGLLPTLLGKATKAVPALRLSGKEYVCLLKLH---KEMPQKLVRKVCEEF 128

Query: 162 TGPLYQRPPLISAVKRQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLL 221
           TGP+YQ PP+ SAVKR +RIRTIY  ++LE +     VLF V CEAGTYIR LC  +GL 
Sbjct: 129 TGPIYQMPPIKSAVKRVIRIRTIYYLEVLEIEGS--FVLFRVGCEAGTYIRKLCHDIGLA 186

Query: 222 LGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPLESLLVHH 281
           LG GGHMQELRR ++G  +E + +VT+ D+ DA  L+    DES +RRVI P+E+ + H 
Sbjct: 187 LGCGGHMQELRRTKAGPFTE-ETLVTLQDLKDAYVLWKEDGDESEIRRVIMPMETAVSHL 245

Query: 282 KRIVIKDSCVNAVCYGAKLMLPGVLRYENDIECGEEVVIMTTKGEAVALAIAHMSTSEIA 341
            +I+++DS V+A+C GA L +PG+   + +++ GE + + T KGE VALA A MST E+ 
Sbjct: 246 PKIILRDSAVDAICSGAALAVPGITSLDANLKKGELIALFTLKGELVALAKAEMSTEELL 305

Query: 342 SCDHGVVARIKRVVMERDLYPRRW 365
               G+ A   R++ME   YP+ W
Sbjct: 306 KASTGLAATSVRIMMEIGTYPKGW 329

ref|NP_613420.1| Pseudouridine synthase of the TruB family [Methanopyrus kandleri AV19]
gb|AAM01350.1| Pseudouridine synthase of the TruB family [Methanopyrus kandleri AV19]
sp|Q8TZ08|TRUB_METKA Probable tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(338 aa)

Score: 289 bits (740), Expect: 1.01282e-76
Length: 326, Idn/Pos/Gap = 157/209/6 (48%/64%/1%)

Query:  42 DRLNVRTTHYTPIPDAGYSPLKRPIQEYIRSGVINLDKPANPSSHEVVAWIKRILRVEKT 101
           DR  +        P  G  P +RPI+EYI  GVINLDKPA P+SHEVVAW+K I  + K 
Sbjct:  14 DREMITKAEVETDPRYGCPPEERPIEEYIMKGVINLDKPAGPTSHEVVAWVKEIFGLSKA  73

Query: 102 GHSGTLDPQVTGCLIVCIERATRLVKSQQSAGKEYVAVLRLHGMRPELDEATVRRAIETL 161
           GH GTLDP+VTG L + +E+AT+++++   AGKEYV ++ LHG   ++DE  + R ++  
Sbjct:  74 GHGGTLDPKVTGVLPIALEKATKIIQTLLPAGKEYVTIMHLHG---DVDEEELERVVKEF 130

Query: 162 TGPLYQRPPLISAVKRQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLL 221
            G + QRPPL SAVKR++R + IY   +LE D   R VL  V C+AGTYIR LC  +G  
Sbjct: 131 EGTILQRPPLRSAVKRRVRPKKIYYIDILEIDG--RDVLMRVGCQAGTYIRKLCHDIGEA 188

Query: 222 LGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPLESLLVHH 281
           LGVG HM ELRR R+G  SE +  VT+HDV DA   +     E  LR V++P+E  L H 
Sbjct: 189 LGVGAHMAELRRTRTGPFSE-ENAVTLHDVKDAYEFWKEEGWEEPLRHVVRPMEEGLEHL 247

Query: 282 KRIVIKDSCVNAVCYGAKLMLPGVLRYENDIECGEEVVIMTTKGEAVALAIAHMSTSEIA 341
            RI I+D+ V+A+C+GA L  PG++R E  I+ G+ V I T KGEAVAL +A  +  E+ 
Sbjct: 248 PRIEIRDTAVDAICHGANLAAPGIVRVEKGIQPGDLVAIFTLKGEAVALGVAKATWKEML 307

Query: 342 SCDHGVVARIKRVVMERDLYPRRWGL 367
             D G++   KRV+ME   YP+ WGL
Sbjct: 308 HADRGIMVDTKRVLMEPGTYPKAWGL 333

ref|NP_143494.1| centromere/microtubule binding protein [Pyrococcus horikoshii OT3]
sp|O59357|TRUB_PYRHO Probable tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
dbj|BAA30756.1| 334aa long hypothetical centromere/microtubule binding protein [Pyrococcus horikoshii OT3]
(334 aa)

Score: 287 bits (734), Expect: 4.66292e-76
Length: 311, Idn/Pos/Gap = 157/206/5 (50%/66%/1%)

Query:  55 PDAGYSPLKRPIQEYIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGC 114
           P  G+ P +RPI+ +I+ GVINLDKP  P+SHEVVAWIKRIL +EK GH GTLDP+V+G 
Sbjct:  29 PKWGFPPYERPIELHIQYGVINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDPKVSGV  88

Query: 115 LIVCIERATRLVKSQQSAGKEYVAVLRLHGMRPELDEATVRRAIETLTGPLYQRPPLISA 174
           L V +E+ATR+V++   AGKEYVA++ LHG  PE     V +  E   G + QRPPL SA
Sbjct:  89 LPVALEKATRVVQALLPAGKEYVALMHLHGDVPENKIIDVMKEFE---GEIIQRPPLRSA 145

Query: 175 VKRQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRV 234
           VKR+LR R +Y  ++LE D   R VLF V  EAGTYIR+L  H+GL LGVG HM ELRR 
Sbjct: 146 VKRRLRTRKVYYIEILEIDG--RDVLFKVGVEAGTYIRSLIHHIGLALGVGAHMAELRRT 203

Query: 235 RSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPLESLLVHHKRIVIKDSCVNAV 294
           RSG   E + +VT+HD++D    +     E YLRR I+P+E  + H  +I IKDS V AV
Sbjct: 204 RSGPFKEDETLVTLHDLVDYYHFWKEDGIEKYLRRAIQPMEKAVEHLPKIWIKDSAVAAV 263

Query: 295 CYGAKLMLPGVLRYENDIECGEEVVIMTTKGEAVALAIAHMSTSEIASCDHGVVARIKRV 354
            +GA L +PG+++    I+ G+ V IMT K E VAL  A M++ E+     G+   +++V
Sbjct: 264 AHGANLTVPGIVKLNVGIKRGDLVAIMTLKDELVALGKAMMTSQEMMQRSKGIAVDVEKV 323

Query: 355 VMERDLYPRRW 365
            M RD YP+ W
Sbjct: 324 FMPRDWYPKLW 334

ref|NP_069076.1| centromere/microtubule-binding protein (cbf5) [Archaeoglobus fulgidus DSM 4304]
gb|AAB90995.1| centromere/microtubule-binding protein (cbf5) [Archaeoglobus fulgidus DSM 4304]
sp|O30001|TRUB_ARCFU Probable tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(325 aa)

Score: 285 bits (729), Expect: 1.9585e-75
Length: 308, Idn/Pos/Gap = 153/200/6 (49%/64%/1%)

Query:  58 GYSPLKRPIQEYIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIV 117
           G  P KRP++EYIR G++ +DKP  PSSHEVV W++RIL V KTGH+GTLDP+VTG L +
Sbjct:  19 GCYPTKRPMEEYIRKGLVCIDKPMGPSSHEVVVWVRRILNVSKTGHAGTLDPRVTGVLPI  78

Query: 118 CIERATRLVKSQQSAGKEYVAVLRLHGMRPELDEATVRRAIETLTGPLYQRPPLISAVKR 177
            IE AT++VK  Q + KEYV ++RLHG     D   V + ++   G +YQRPPL SAVK+
Sbjct:  79 FIENATKMVKFLQESSKEYVCLMRLHGDAKRED---VEKVMKLFVGRIYQRPPLKSAVKK 135

Query: 178 QLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSG 237
            LRIR IYE +LLE +   R VLF V  E+GTYIR LC  +G +LG G HMQELRR R+G
Sbjct: 136 VLRIREIYEMELLEMEG--RDVLFRVVTESGTYIRKLCRDIGEVLGTGAHMQELRRTRTG 193

Query: 238 VHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPLESLLVHHKRIVIKDSCVNAVCYG 297
              E D   T+ D+LDA   +    +E YLR +IKP+E       +IVIKDS V+A+C+G
Sbjct: 194 KFGE-DMCYTLQDLLDAYVFWKEEGEEKYLREIIKPMEVAAAELPKIVIKDSAVDAICHG 252

Query: 298 AKLMLPGVLRYENDIECGEEVVIMTTKGEAVALAIAHMSTSEIASCDHGVVARIKRVVME 357
           A L + GV   E +++    V I T K E VA+  A M   +I     G+ A I+RV+ME
Sbjct: 253 ANLSVRGVAYVEKNVKKDSTVAIFTLKNELVAIGRALMDAEDIYRLKKGIAADIQRVMME 312

Query: 358 RDLYPRRW 365
           R +YP+ W
Sbjct: 313 RGVYPKVW 320

ref|NP_616049.1| rRNA pseudouridine synthase [Methanosarcina acetivorans C2A]
gb|AAM04529.1| rRNA pseudouridine synthase [Methanosarcina acetivorans str. C2A]
sp|Q8TRR5|TRUB_METAC Probable tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(338 aa)

Score: 284 bits (726), Expect: 3.7861e-75
Length: 325, Idn/Pos/Gap = 157/211/8 (48%/64%/2%)

Query:  42 DRLNVRTTHYTPIPDAGYSPLKRPIQEYIRSGVINLDKPANPSSHEVVAWIKRILRVEKT 101
           +R  VR +     P  G +P KRPI EYI  GV+N+DKP+ P+SHEV AW+K IL V   
Sbjct:  12 ERTLVRKSGAWTNPVYGCAPEKRPILEYIEKGVVNIDKPSGPTSHEVAAWVKAILGVNTA  71

Query: 102 GHSGTLDPQVTGCLIVCIERATRLVKSQQSAGKEYVAVLRLH-GMRPELDEATVRRAIET 160
           GH+G+LDP+VTG L   + +AT+ V + + +GKEYV  L+LH  M P+L    VR+  E 
Sbjct:  72 GHAGSLDPKVTGLLPTLLGKATKAVPALRLSGKEYVCHLKLHRAMPPKL----VRKVCEE 127

Query: 161 LTGPLYQRPPLISAVKRQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGL 220
            TGP+YQ PP+ SAVKR +R+RTIY  ++LE +     VLF V CEAGTYIR LC  +GL
Sbjct: 128 FTGPIYQMPPIKSAVKRVIRVRTIYYIEVLEIEGMS--VLFRVGCEAGTYIRKLCHDIGL 185

Query: 221 LLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPLESLLVH 280
            LG GGHMQ LRR ++G  +E   +VT+H++ DA   +    DES LRRVI+P+ES + H
Sbjct: 186 ALGCGGHMQALRRTKAGPFTE-KTLVTLHELKDAYVFWKEDGDESELRRVIRPMESAVSH 244

Query: 281 HKRIVIKDSCVNAVCYGAKLMLPGVLRYENDIECGEEVVIMTTKGEAVALAIAHMSTSEI 340
             +I+++DS V+AVC GA L +PG+   ++ +  GE   + T KGE VALA A M+T EI
Sbjct: 245 LPKIILRDSAVDAVCSGASLAVPGITSLDSSLAEGELAALFTLKGELVALAKAEMNTEEI 304

Query: 341 ASCDHGVVARIKRVVMERDLYPRRW 365
                G+ A   RV+ME   YP+ W
Sbjct: 305 LKASAGIAASPIRVLMEAGTYPKGW 329

ref|NP_579514.1| hypothetical centromere binding protein/pseudouridine synthase [Pyrococcus furiosus DSM 3638]
gb|AAL81909.1| centromere binding protein homolog/pseudouridine synthase [Pyrococcus furiosus DSM 3638]
sp|Q7LWY0|TRUB_PYRFU Probable tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(340 aa)

Score: 284 bits (726), Expect: 3.84981e-75
Length: 311, Idn/Pos/Gap = 153/206/5 (49%/66%/1%)

Query:  55 PDAGYSPLKRPIQEYIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGC 114
           PD G+ P KRPI+ +I+ GVINLDKP  P+SHEVVAWIK+IL +EK GH GTLDP+V+G 
Sbjct:  29 PDWGFPPEKRPIEMHIQFGVINLDKPPGPTSHEVVAWIKKILNLEKAGHGGTLDPKVSGV  88

Query: 115 LIVCIERATRLVKSQQSAGKEYVAVLRLHGMRPELDEATVRRAIETLTGPLYQRPPLISA 174
           L V +E+ATR+V++   AGKEYVA++ LHG  PE     V +  E   G + QRPPL SA
Sbjct:  89 LPVALEKATRVVQALLPAGKEYVALMHLHGDVPEDKIIQVMKEFE---GEIIQRPPLRSA 145

Query: 175 VKRQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRV 234
           VKR+LR R +Y  ++LE +   R VLF V  EAGTYIR+L  H+GL LGVG HM ELRR 
Sbjct: 146 VKRRLRTRKVYYIEVLEIEG--RDVLFRVGVEAGTYIRSLIHHIGLALGVGAHMSELRRT 203

Query: 235 RSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPLESLLVHHKRIVIKDSCVNAV 294
           RSG   E + ++T+HD++D  + +     E Y R+ I+P+E  + H  ++ IKDS V AV
Sbjct: 204 RSGPFKEDETLITLHDLVDYYYFWKEDGIEEYFRKAIQPMEKAVEHLPKVWIKDSAVAAV 263

Query: 295 CYGAKLMLPGVLRYENDIECGEEVVIMTTKGEAVALAIAHMSTSEIASCDHGVVARIKRV 354
            +GA L +PG+ +    I+ G+ V IMT K E VAL  A M++ E+     G+   +++V
Sbjct: 264 THGADLAVPGIAKLHAGIKRGDLVAIMTLKDELVALGKAMMTSQEMLEKTKGIAVDVEKV 323

Query: 355 VMERDLYPRRW 365
            M RD YP+ W
Sbjct: 324 FMPRDWYPKLW 334

ref|ZP_00147704.2| COG0130: Pseudouridine synthase [Methanococcoides burtonii DSM 6242]
(331 aa)

Score: 283 bits (725), Expect: 5.15546e-75
Length: 324, Idn/Pos/Gap = 145/213/8 (44%/65%/2%)

Query:  44 LNVRTTHYTPIPDAGYS--PLKRPIQEYIRSGVINLDKPANPSSHEVVAWIKRILRVEKT 101
           +N+    +    +A Y   P  RPI EYI  GV+N+DK   P+SHEV AW++ +L V+K 
Sbjct:  11 VNIMVEKFHATTNAAYGCLPQDRPILEYINMGVVNIDKAIGPTSHEVTAWVRDMLGVKKA  70

Query: 102 GHSGTLDPQVTGCLIVCIERATRLVKSQQSAGKEYVAVLRLHGMRPELDEATVRRAIETL 161
           GHSG+LDP VTG L V + RAT+ V + + +GKEY+ V+ LH    ++ +  +R+A +  
Sbjct:  71 GHSGSLDPHVTGLLPVMLGRATKAVSALRLSGKEYICVMHLHD---DIPDRKIRKACKEF 127

Query: 162 TGPLYQRPPLISAVKRQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLL 221
           TGP+YQ PP+ISAVKRQLRIR IY   +LE +   R VL  V CEAGTY+R LC  +GL+
Sbjct: 128 TGPIYQTPPIISAVKRQLRIRNIYYLDVLEIEG--REVLMRVGCEAGTYLRKLCHDIGLV 185

Query: 222 LGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPLESLLVHH 281
           LG GGHM++LRR  +G   E D +V+++D+ DA   +    DES LR++++P+E  L H 
Sbjct: 186 LGCGGHMKQLRRTGTGPFRE-DTLVSLYDLKDACVFWQEDGDESELRKLVRPMEEGLSHL 244

Query: 282 KRIVIKDSCVNAVCYGAKLMLPGVLRYENDIECGEEVVIMTTKGEAVALAIAHMSTSEIA 341
            +I+I+DS V+AVC GA L +PG++ +   I+  +++ + T KGEAVAL  + M+  E+ 
Sbjct: 245 PKIIIRDSAVDAVCRGASLAVPGIVSFSKCIQKDDKIAVFTLKGEAVALCRSFMNADELE 304

Query: 342 SCDHGVVARIKRVVMERDLYPRRW 365
           +  HG+    +RV+M+  +YPR W
Sbjct: 305 NESHGIACITERVIMDAAIYPRCW 328

dbj|BAD85698.1| tRNA pseudouridine synthase B [Thermococcus kodakaraensis KOD1]
ref|YP_183922.1| tRNA pseudouridine synthase B [Thermococcus kodakaraensis KOD1]
sp|Q5JJE8|TRUB_PYRKO Probable tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(338 aa)

Score: 281 bits (718), Expect: 3.09992e-74
Length: 311, Idn/Pos/Gap = 153/202/5 (49%/64%/1%)

Query:  55 PDAGYSPLKRPIQEYIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGC 114
           P  G+ P KRPI+ +I+ G+INLDKP  P+SHEVVAW+KRIL + K GH GTLDP+V+G 
Sbjct:  29 PKWGFPPEKRPIEMHIQFGIINLDKPPGPTSHEVVAWVKRILNLNKAGHGGTLDPKVSGV  88

Query: 115 LIVCIERATRLVKSQQSAGKEYVAVLRLHGMRPELDEATVRRAIETLTGPLYQRPPLISA 174
           L V +ERATR+V++   AGKEYVA++ LHG  PE     V R  +   G + QRPPL SA
Sbjct:  89 LPVALERATRVVQALLPAGKEYVALMHLHGDVPEDKILAVMREFQ---GEIIQRPPLRSA 145

Query: 175 VKRQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRV 234
           VKR+LR R +Y   +LE +   R VLF V  EAGTYIR+L  H+GL LGVG HM ELRR 
Sbjct: 146 VKRRLRTRKVYYIDVLEIEG--RDVLFRVGVEAGTYIRSLIHHIGLALGVGAHMAELRRT 203

Query: 235 RSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPLESLLVHHKRIVIKDSCVNAV 294
           RSG   E + +VT+HD++D    +     E Y R+ I+P+E  + H  ++ I+DS V AV
Sbjct: 204 RSGPFKEDETLVTLHDLVDYYHFWKEDGVEEYFRKAIQPMEKAVEHLPKVWIRDSAVAAV 263

Query: 295 CYGAKLMLPGVLRYENDIECGEEVVIMTTKGEAVALAIAHMSTSEIASCDHGVVARIKRV 354
            +GA L +PGV++    I+ G+ V IMT K E VAL  A M+T E+     G+   + +V
Sbjct: 264 THGADLAVPGVVKLHKGIKKGDLVAIMTLKDELVALGKAMMTTGEMLQKSKGIAVDVDKV 323

Query: 355 VMERDLYPRRW 365
            M RD YP+ W
Sbjct: 324 FMPRDWYPKLW 334

ref|NP_634178.1| tRNA pseudouridine synthase [Methanosarcina mazei Go1]
gb|AAM31850.1| tRNA pseudouridine synthase [Methanosarcina mazei Goe1]
sp|Q8PV20|TRUB_METMA Probable tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(338 aa)

Score: 281 bits (718), Expect: 3.42637e-74
Length: 324, Idn/Pos/Gap = 153/207/6 (47%/63%/1%)

Query:  42 DRLNVRTTHYTPIPDAGYSPLKRPIQEYIRSGVINLDKPANPSSHEVVAWIKRILRVEKT 101
           +R  VR +     P  G  P KRPI EYI  GV+N+DKP  P+SHEV AW+K IL V   
Sbjct:  12 ERTLVRKSGAWTNPAYGCPPEKRPIHEYIEKGVVNIDKPRGPTSHEVAAWVKAILGVHTA  71

Query: 102 GHSGTLDPQVTGCLIVCIERATRLVKSQQSAGKEYVAVLRLHGMRPELDEATVRRAIETL 161
           GH+G+LDP+VTG L   + +AT  V + + +GKEY+  L+LH   P+     VR+  E  
Sbjct:  72 GHAGSLDPKVTGLLPTLLGKATLAVPALRLSGKEYICHLKLHRAMPQ---KLVRQVCEEF 128

Query: 162 TGPLYQRPPLISAVKRQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLL 221
           TGP+YQ PP+ SAVKR +R+RTIY  ++LE +     VLF V CEAGTYIR LC  +GL 
Sbjct: 129 TGPIYQMPPIKSAVKRVIRVRTIYHLEVLEIEGTS--VLFRVGCEAGTYIRKLCHDIGLA 186

Query: 222 LGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPLESLLVHH 281
           LG GGHMQ LRR ++G  +E   ++T+H++ DA   +    DES LRRVI+P+ES + H 
Sbjct: 187 LGCGGHMQGLRRTKAGPFTE-KTLITLHELKDAYVFWKEDGDESELRRVIRPMESAVSHL 245

Query: 282 KRIVIKDSCVNAVCYGAKLMLPGVLRYENDIECGEEVVIMTTKGEAVALAIAHMSTSEIA 341
            +I+++DS V+A+C GA L +PG+   ++++  GE   + T KGE VALA A M+T EI 
Sbjct: 246 PKIILRDSAVDAICSGASLAVPGITGLDSNLAEGELTGLFTLKGELVALAKAKMTTEEIL 305

Query: 342 SCDHGVVARIKRVVMERDLYPRRW 365
               G+ A   RV+ME   YPR W
Sbjct: 306 KASAGIAASPIRVLMEAGTYPRGW 329

gb|AAB84541.1| centromere/microtubule-binding protein [Methanothermobacter thermautotrophicus str. Delta H]
ref|NP_275177.1| centromere/microtubule-binding protein [Methanothermobacter thermautotrophicus str. Delta H]
sp|O26140|TRUB_METTH Probable tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(324 aa)

Score: 277 bits (708), Expect: 4.6282e-73
Length: 329, Idn/Pos/Gap = 149/209/10 (45%/63%/3%)

Query:  37 LLKNYDRLNVRTTHYTPIPDAGYSPLKRPIQEYIRSGVINLDKPANPSSHEVVAWIKRIL  96
           L+ N+  L   TT+    PD G  P +R I+ +I  GV+NLDKP+ P+SH+V +W++ +L
Sbjct:   5 LMANFIELKEATTN----PDYGCPPAERDIEAHISMGVVNLDKPSGPTSHQVDSWVRDML  60

Query:  97 RVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAGKEYVAVLRLHGMRPELDEATVRR 156
            VEK GH GTLDP+VTG L + I+RATR+++    A KEYV ++R+H    E+DE  +R 
Sbjct:  61 HVEKVGHGGTLDPKVTGVLPLGIDRATRVMQLLLEAPKEYVCLMRVH---REVDEERIRE 117

Query: 157 AIETLTGPLYQRPPLISAVKRQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCV 216
            +    G ++Q PPL SAVKR LR+RTIY   +LE D +   VLF ++CEAGTY+R  C 
Sbjct: 118 VLGEFQGKIFQIPPLKSAVKRDLRVRTIYRVDILEVDGQD--VLFRIACEAGTYVRKYCH 175

Query: 217 HLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPLES 276
            +G  LG G HM ELRR   G  +E +G+VT+HD+ DA   +    DE++LR  I P+E 
Sbjct: 176 DVGEALGAGAHMAELRRTAVGPFTE-EGLVTLHDLKDAYQFWVEDGDETFLRECILPMEF 234

Query: 277 LLVHHKRIVIKDSCVNAVCYGAKLMLPGVLRYENDIECGEEVVIMTTKGEAVALAIAHMS 336
            + H  R+VI DS V+A+C+GA L   G+   +++I  G+ V IMT KGE V +  A MS
Sbjct: 235 AVGHLPRVVILDSAVDAICHGADLARGGIAGLDDNIAWGDTVAIMTLKGELVGVGEASMS 294

Query: 337 TSEIASCDHGVVARIKRVVMERDLYPRRW 365
             +IA+ D G+V   ++V ME   YPR W
Sbjct: 295 ALDIAAADGGLVIETRKVFMEPGTYPRMW 323

ref|NP_247116.1| centromere/microtubule-binding protein (cbf5) [Methanocaldococcus jannaschii DSM 2661]
gb|AAB98132.1| centromere/microtubule-binding protein (cbf5) [Methanocaldococcus jannaschii DSM 2661]
sp|Q57612|TRUB_METJA Probable tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(336 aa)

Score: 276 bits (707), Expect: 6.46186e-73
Length: 310, Idn/Pos/Gap = 148/201/6 (47%/64%/1%)

Query:  56 DAGYSPLKRPIQEYIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCL 115
           D G +P +R I++ I+ GV+ +DKP  P+SHEV  W+K+IL ++K GH GTLDP+VTG L
Sbjct:  29 DYGCNPYERKIEDLIKYGVVVVDKPRGPTSHEVSTWVKKILNLDKAGHGGTLDPKVTGVL  88

Query: 116 IVCIERATRLVKSQQSAGKEYVAVLRLHGMRPELDEATVRRAIETLTGPLYQRPPLISAV 175
            V +ERAT+ +       KEYV ++ LH    +  E  + R  +  TG +YQRPPL +AV
Sbjct:  89 PVALERATKTIPMWHIPPKEYVCLMHLH---RDASEEDILRVFKEFTGRIYQRPPLKAAV 145

Query: 176 KRQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVR 235
           KR+LRIR I+E +LL+ D K   VLF V C++GTYIR LC  +G  LG   HMQELRR +
Sbjct: 146 KRRLRIRKIHELELLDKDGKD--VLFRVKCQSGTYIRKLCEDIGEALGTSAHMQELRRTK 203

Query: 236 SGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPLESLLVHHKRIVIKDSCVNAVC 295
           SG   E D  V + D+LDA   +    DE  LRRVIKP+E  L H K++V+KDS V+A+C
Sbjct: 204 SGCFEEKDA-VYLQDLLDAYVFWKEDGDEEELRRVIKPMEYGLRHLKKVVVKDSAVDAIC 262

Query: 296 YGAKLMLPGVLRYENDIECGEEVVIMTTKGEAVALAIAHMSTSEIASCDHGVVARIKRVV 355
           +GA + + G+ +    I  GE V++ T KGEAVA+  A M+T EI + D GV   ++RV 
Sbjct: 263 HGADVYVRGIAKLSKGIGKGETVLVETLKGEAVAVGKALMNTKEILNADKGVAVDVERVY 322

Query: 356 MERDLYPRRW 365
           M+R  YPR W
Sbjct: 323 MDRGTYPRMW 332

ref|XP_420191.1| PREDICTED: similar to Dyskerin (Nucleolar protein NAP57) (CBF5 homolog) [Gallus gallus]
(276 aa)

Score: 261 bits (668), Expect: 2.04609e-68
Length: 172, Idn/Pos/Gap = 122/147/0 (70%/85%/0%)

Query: 228 MQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPLESLLVHHKRIVIK 287
           MQELRRVRSG+  E D MVTMHDVLDAQW +D  KD+SYLRRVI PLE LL  HKR+V+K
Sbjct:   1 MQELRRVRSGILGEMDNMVTMHDVLDAQWQYDNNKDDSYLRRVILPLEKLLTSHKRLVMK  60

Query: 288 DSCVNAVCYGAKLMLPGVLRYENDIECGEEVVIMTTKGEAVALAIAHMSTSEIASCDHGV 347
           DS VNA+CYGAK+MLPGVLRYE+ IE  +E+V++TTKGEA+ LAIA M+T+ I++CDHGV
Sbjct:  61 DSAVNAICYGAKIMLPGVLRYEDGIELNQEIVVITTKGEAICLAIALMTTAVISTCDHGV 120

Query: 348 VARIKRVVMERDLYPRRWGLGPVASRKKAMIQRGELDKHGRPNEHTPSDWRR 399
           VA+IKRV+MERD YPR+WGLGP AS+KK MIQ+G LDKHG+PNE TP  W++
Sbjct: 121 VAKIKRVIMERDTYPRKWGLGPKASQKKMMIQKGLLDKHGKPNECTPDSWKK 172

emb|CAH75164.1| conserved hypothetical protein [Plasmodium chabaudi]
(246 aa)

Score: 259 bits (663), Expect: 8.24276e-68
Length: 185, Idn/Pos/Gap = 115/149/0 (62%/80%/0%)

Query: 213 TLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIK 272
           TLC H+GLLLGVG HMQELRRV+SG  +EYD M T+HD++DAQ+++DTT DE+YLR++I 
Sbjct:   1 TLCEHIGLLLGVGAHMQELRRVKSGNMTEYDNMCTLHDIMDAQYIYDTTGDETYLRKIIT  60

Query: 273 PLESLLVHHKRIVIKDSCVNAVCYGAKLMLPGVLRYENDIECGEEVVIMTTKGEAVALAI 332
           PLE LL++  RIVIKDS VNA+CYGAKL +PGVLR++N+I+   E+V+MTTKGEAVALAI
Sbjct:  61 PLEKLLINFPRIVIKDSAVNAICYGAKLTIPGVLRFDNNIDVYSEIVLMTTKGEAVALAI 120

Query: 333 AHMSTSEIASCDHGVVARIKRVVMERDLYPRRWGLGPVASRKKAMIQRGELDKHGRPNEH 392
           A M+++ IA+ DHG+VA  KRV+M+RD Y  +WG G  +  KK +I  G LDK+G+PNE 
Sbjct: 121 AQMTSTVIATVDHGIVALTKRVIMDRDTYDVKWGFGNRSMEKKKLILAGLLDKYGKPNEK 180

Query: 393 TPSDW 397
           TP  W
Sbjct: 181 TPISW 185

ref|XP_603972.1| PREDICTED: similar to DYSKERIN [Bos taurus]
(547 aa)

Score: 254 bits (648), Expect: 4.71564e-66
Length: 170, Idn/Pos/Gap = 130/152/0 (76%/89%/0%)

Query: 200 LFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFD 259
           +FWVSCEAGTYIRTLCVHLGLLLGVGG MQELRRVRSGV SE D MVTMHDVLDAQWL+D
Sbjct: 194 IFWVSCEAGTYIRTLCVHLGLLLGVGGQMQELRRVRSGVMSEKDHMVTMHDVLDAQWLYD 253

Query: 260 TTKDESYLRRVIKPLESLLVHHKRIVIKDSCVNAVCYGAKLMLPGVLRYENDIECGEEVV 319
             KDESYLRRV+ PLE LL  HKR+V+KDS VNA+CYGAK+MLPGVLRYE+ IE  +E+V
Sbjct: 254 NHKDESYLRRVVYPLEKLLTSHKRLVMKDSAVNAICYGAKIMLPGVLRYEDGIEVNQEIV 313

Query: 320 IMTTKGEAVALAIAHMSTSEIASCDHGVVARIKRVVMERDLYPRRWGLGP 369
           ++TTKGEA+ +AIA M+T+ I++CDHG+VA+IKRV+MERD YPR+WGLGP
Sbjct: 314 VITTKGEAICMAIALMTTAVISTCDHGIVAKIKRVIMERDTYPRKWGLGP 363

ref|NP_558900.1| tRNA pseudouridine synthase B [Pyrobaculum aerophilum str. IM2]
gb|AAL63082.1| tRNA pseudouridine synthase B [Pyrobaculum aerophilum str. IM2]
sp|Q8ZYB3|TRUB_PYRAE Probable tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(333 aa)

Score: 250 bits (638), Expect: 6.92395e-65
Length: 311, Idn/Pos/Gap = 131/195/6 (42%/62%/1%)

Query:  55 PDAGYSPLKRPIQEYIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGC 114
           P  G  P +R  +EYI+  ++ LDKP  PSSHEV AW+K+IL VE+ GH+GTLDP+V+G 
Sbjct:  18 PQWGKPPSQRSTEEYIKYSLVILDKPRGPSSHEVAAWVKKILGVERAGHAGTLDPKVSGV  77

Query: 115 LIVCIERATRLVKSQQSAGKEYVAVLRLHGMRPELDEATVRRAIETLTGPLYQRPPLISA 174
           L + I   T+++ +   + K YVAV + HG   ++DE  +R  ++   G +YQ+PPL SA
Sbjct:  78 LPIAIAEGTKVLMALSRSDKVYVAVAKFHG---DVDEDKLRAVLQEFQGVIYQKPPLRSA 134

Query: 175 VKRQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRV 234
           VKRQLR R +Y   LLE D +  ++   V  EAGTY R +   +G +LGVG +M+ELRR+
Sbjct: 135 VKRQLRTRRVYSLDLLELDGRYAVIKMHV--EAGTYARKIIHDIGEVLGVGANMRELRRI 192

Query: 235 RSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPLESLLVHHKRIVIKDSCVNAV 294
               ++E D  VT+ D+ DA +++    D++YLRRV+ P+E +  H  +I ++DS V+A+
Sbjct: 193 AVSCYTE-DEAVTLQDIADAYYIWKHYGDDTYLRRVLLPIEEIARHLPKIWVRDSAVDAI 251

Query: 295 CYGAKLMLPGVLRYENDIECGEEVVIMTTKGEAVALAIAHMSTSEIASCDHGVVARIKRV 354
           C GA L  PG+ ++E     G+ V + T KGE + +  A + + E+   + G+VAR  RV
Sbjct: 252 CNGAPLAAPGISKFETPFSKGDLVAMFTLKGELIGIGRALVGSEEVKKMERGLVARTDRV 311

Query: 355 VMERDLYPRRW 365
           VM R  YP  W
Sbjct: 312 VMRRGTYPAMW 322

emb|CAF31242.1| pseudouridine syntase related protein [Methanococcus maripaludis S2]
ref|NP_988806.1| pseudouridine syntase related protein [Methanococcus maripaludis S2]
sp|Q6LWM3|TRUB_METMP Probable tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(333 aa)

Score: 241 bits (614), Expect: 3.8004e-62
Length: 308, Idn/Pos/Gap = 133/186/6 (43%/60%/1%)

Query:  58 GYSPLKRPIQEYIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIV 117
           G  P  R I+  + +G++ +DKP+ P+SHEV AW++ +L + K GH GTLDP+VTG L V
Sbjct:  16 GSDPYNRDIKTLLNTGLVVIDKPSGPTSHEVAAWVRNMLNLVKAGHGGTLDPKVTGALPV  75

Query: 118 CIERATRLVKSQQSAGKEYVAVLRLHGMRPELDEATVRRAIETLTGPLYQRPPLISAVKR 177
            +   T+ V       KEYV ++ LH     +D   +    +  TG ++QRPPL +AVKR
Sbjct:  76 ALGNTTKCVPIWHIPPKEYVCLMHLHDDAELVD---IENIFKEFTGRIHQRPPLKAAVKR 132

Query: 178 QLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSG 237
            LRIR IYE ++LE D   R +LF   C++GTY+R L   +G  LG   HMQELRR  SG
Sbjct: 133 SLRIRKIYEIEILEIDG--RDILFRTKCQSGTYLRKLVDDMGEALGTSAHMQELRRTISG 190

Query: 238 VHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPLESLLVHHKRIVIKDSCVNAVCYG 297
              E +  V + D+LDA   +    +E  LR+++KPLE  L H K+I+IKDS V+AVC+G
Sbjct: 191 PFYENEA-VYLQDLLDAYIFWKEDGNEEELRKIVKPLEYGLQHLKKIIIKDSAVDAVCHG 249

Query: 298 AKLMLPGVLRYENDIECGEEVVIMTTKGEAVALAIAHMSTSEIASCDHGVVARIKRVVME 357
           A L   G+ + E  +   E V+I T KGEAVA+    M+T ++   + G V  I RV+ME
Sbjct: 250 ATLYSSGISKIEKGLGTDEVVLIETLKGEAVAVGKPLMNTKDMLKTEEGEVVEITRVIME 309

Query: 358 RDLYPRRW 365
             +YPR W
Sbjct: 310 PGIYPRIW 317

ref|NP_963737.1| hypothetical protein NEQ454 [Nanoarchaeum equitans Kin4-M]
sp|P60346|TRUB_NANEQ Probable tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
gb|AAR39298.1| NEQ454 [Nanoarchaeum equitans Kin4-M]
(348 aa)

Score: 236 bits (603), Expect: 6.64874e-61
Length: 308, Idn/Pos/Gap = 132/195/7 (42%/63%/2%)

Query:  58 GYSPLKRPIQEYIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIV 117
           G  P  RPI+  ++  VINLDKP+ P+SH+VVAW++ I+ V K GH GTLDP+VTG L +
Sbjct:  44 GEDPYNRPIERLLKYSVINLDKPSGPTSHQVVAWVRDIVGV-KAGHGGTLDPKVTGVLPI 102

Query: 118 CIERATRLVKSQQSAGKEYVAVLRLHGMRPELDEATVRRAIETLTGPLYQRPPLISAVKR 177
            I  AT+++++   AGKEYVA++ LH    E+ E  + + +    G + Q PPL SAVK+
Sbjct: 103 AIGEATKVLQTLLIAGKEYVALMHLH---KEVSEKDIIKVMSKFVGTIIQTPPLRSAVKK 159

Query: 178 QLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSG 237
           + R + +Y  K++E D K   VLF VS + G YIR L   +G+ LGVG HMQELRR++SG
Sbjct: 160 RPRKKKVYCIKIIEIDGKD--VLFRVSTQGGVYIRKLIHDIGVKLGVGAHMQELRRIKSG 217

Query: 238 VHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPLESLLVHHKRIVIKDSCVNAVCYG 297
              E +  V + D++D+ + +    +E Y+R+V  P+E  + H K+I I DS V A+ +G
Sbjct: 218 PFHE-NNSVYLQDIVDSLYFWKEEGNEEYIRKVFLPVEEAVKHLKKIYILDSAVAAIVHG 276

Query: 298 AKLMLPGVLRYENDIECGEEVVIMTTKGEAVALAIAHMSTSEIASCDHGVVARIKRVVME 357
           A L +PG+ +  ++I+ G+ V I T KGE VA+ IA M + E+     G+   I+RV M+
Sbjct: 277 ANLAVPGIAKLYSNIKKGDLVSIHTLKGELVAIGIALMDSKEMLEKKRGIAVDIERVFMK 336

Query: 358 RDLYPRRW 365
             LYP+ W
Sbjct: 337 PGLYPKMW 344

ref|NP_341930.1| tRNA pseudouridine synthase subunit B (truB) [Sulfolobus solfataricus P2]
gb|AAK40720.1| tRNA pseudouridine synthase subunit B (truB) [Sulfolobus solfataricus P2]
sp|Q980C3|TRUB_SULSO Probable tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(251 aa)

Score: 213 bits (542), Expect: 8.34563e-54
Length: 251, Idn/Pos/Gap = 106/167/6 (42%/66%/2%)

Query: 115 LIVCIERATRLVKSQQSAGKEYVAVLRLHGMRPELDEATVRRAIETLTGPLYQRPPLISA 174
           L + IE AT+++      GKEYV V+++H    E ++  + + I +  G +YQRPP+ S+
Sbjct:   2 LPIGIENATKIMNYISKGGKEYVCVMQVHC---EYNKEELAKIISSFKGEIYQRPPVRSS  58

Query: 175 VKRQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRV 234
           VKR+LRIR IY+ ++L+ D  ++LVL  V+C++GTY+R LC  +G++ G G HM+ELRR 
Sbjct:  59 VKRRLRIRRIYDIEILDMD--KKLVLLRVNCDSGTYMRKLCHDIGIIYGCGAHMRELRRT 116

Query: 235 RSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPLESLLVHHKRIVIKDSCVNAV 294
           RSG+ +E   +V +H++ +A +L+   KDE+ LRRV+ P+E       +IVI+DS VNA+
Sbjct: 117 RSGIFTESTNLVKLHELSEAIYLYKNCKDETELRRVLIPMEFATCEIPKIVIEDSAVNAL 176

Query: 295 CYGAKLMLPGVLRYENDIECGEEVVIMTTKGEAVALAIAHMSTSEIASCDHGVVARIKRV 354
            YGA+L +PGV+ Y+N  +  + V ++T KGE VA   A M + E+ +   G+V  + RV
Sbjct: 177 AYGAQLAVPGVVAYQN-FKKNDTVAVLTLKGELVATGNALMDSEELENAKKGIVVNLSRV 235

Query: 355 VMERDLYPRRW 365
            M+RD+YP+ W
Sbjct: 236 FMQRDIYPKAW 246

ref|NP_147652.1| nucleolar protein [Aeropyrum pernix K1]
sp|Q9YDC3|TRUB_AERPE Probable tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
dbj|BAA79974.1| 293aa long hypothetical nucleolar protein [Aeropyrum pernix K1]
(293 aa)

Score: 195 bits (496), Expect: 2.16364e-48
Length: 265, Idn/Pos/Gap = 114/162/6 (43%/61%/2%)

Query: 102 GHSGTLDPQVTGCLIVCIERATRLVKSQQSAGKEYVAVLRLHGMRPELDEATVRRAIETL 161
           G +G   P+VTG L V +ER TR++ +   + KEYV V++LH  RP ++E  +R  ++  
Sbjct:  25 GAAGRGYPKVTGVLPVALERMTRIIGTVMHSSKEYVCVMQLH--RP-VEEDRLREVLKLF  81

Query: 162 TGPLYQRPPLISAVKRQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLL 221
            G +YQ+PPL S+VKR LR R ++  +LLEY  K    L  V CEAGTY+R LC  +GL+
Sbjct:  82 EGEIYQKPPLRSSVKRALRTRRVFRIELLEYTGK--YALLRVDCEAGTYMRKLCWDIGLV 139

Query: 222 LGVGGHMQELRRVRSGVHSEYDG-MVTMHDVLDAQWLFDTTKDESYLRRVIKPLESLLVH 280
           LGVG HM+ELRR+R+G  SE  G MV + DV  A   +     +  LRRV+ P E  + H
Sbjct: 140 LGVGAHMRELRRIRTGPFSEDSGLMVRLDDVAYAVIRWREEGKDDLLRRVVIPGEYSVCH 199

Query: 281 HKRIVIKDSCVNAVCYGAKLMLPGVLRYENDIECGEEVVIMTTKGEAVALAIAHMSTSEI 340
             +++++DS V ++ +GA+L  PGV   E  +E G  V +MT KGE + L  A  S  E+
Sbjct: 200 IPKVLVRDSAVESLTHGAQLAAPGVAAVEEGVEKGGMVALMTLKGELIGLGKALASAQEM 259

Query: 341 ASCDHGVVARIKRVVMERDLYPRRW 365
              + G+V    R++MER LYPR W
Sbjct: 260 LEAERGIVVSPTRIIMERGLYPRMW 284

ref|NP_110871.1| Pseudouridine synthase (dyskerin-related) [Thermoplasma volcanium GSS1]
sp|Q97BU9|TRUB_THEVO Probable tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
dbj|BAB59498.1| centromere/microtubule-binding protein [Thermoplasma volcanium GSS1]
(353 aa)

Score: 186 bits (473), Expect: 9.48028e-46
Length: 352, Idn/Pos/Gap = 117/181/24 (33%/51%/6%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           +G I +DKP  P+SH+V  W+++IL  EK GH GTLDP VTG L++ I +A RL+     
Sbjct:   9 NGFIVIDKPQGPTSHQVDYWVRQILGTEKVGHIGTLDPNVTGVLVMAIGKAVRLIDVVHE  68

Query: 132 AGKEYVAVLRLHGMRPELDEATVRRAIETLTGPLYQRPPLISAVKRQLRIRTIYESKLLE 191
             KEYV V+R H    ++ E  VR      T  +YQ PP+ SAV R++RI+TIYE  ++E
Sbjct:  69 KPKEYVGVMRFHS---DISEEEVREVFRKFTTRIYQLPPVRSAVSRKVRIKTIYELDMIE 125

Query: 192 YDPKRRLVLFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDV 251
              K ++VLF V CE+GTYIRTLC  +G + G GG M +LRR+ +G   E D  +T+ D+
Sbjct: 126 --KKDKIVLFHVKCESGTYIRTLCTDIGYVSGKGGQMVDLRRISTGPFKE-DIAITLQDL 182

Query: 252 LDAQWLFDTTKDESYLRRVIKPLESLLVHHKRIVIKDSCVNAVCYGAKLMLPGVLRYEND 311
                L    KDE + R     +    + + +IV K S V  + +G+ L + GV   + +
Sbjct: 183 QAYVDLAKEGKDELF-RSHFLDMTYAFIDYPKIVAKKSAVENIAHGSDLYVGGVKLIDGN 241

Query: 312 IECGEEVVIMTTKGEAVALAIAHMSTSEIASCDHGVVARIKRVVMERDLYPRRWGLGPVA 371
            + G+ V +++   E +   IA   +S +          +K V  +      + G G V 
Sbjct: 242 FQKGDRVCVLSEDNELLGTGIARCDSSNLF---------MKVVDFDHIFVEAKHGKGDVV 292

Query: 372 SRKKAMIQRGELDKHGRPNEHTPSDWRRVQPELESAPSRMERQAGPPVRPPK 423
             ++  +Q        RP +    + R      +S   R  ++ GP + P +
Sbjct: 293 RDREKDVQ--------RPGQQVHRNIRDAAHGPDSRTGRGRKETGPQIAPNR 336

ref|NP_280486.1| Sus [Halobacterium sp. NRC-1]
gb|AAG19966.1| tRNA-pseudouridine synthase; Sus [Halobacterium sp. NRC-1]
sp|Q9HPA4|TRUB_HALN1 Probable tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(301 aa)

Score: 184 bits (467), Expect: 3.91598e-45
Length: 253, Idn/Pos/Gap = 111/146/14 (43%/57%/5%)

Query:  61 PLKRPIQEYIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIE 120
           P +R     +  GV+NLDKP  PS+H+V AWI+ ++ VEK  H+GTLDP+VTGCL V   
Sbjct:   7 PGERSPAAVLSFGVVNLDKPPGPSAHQVSAWIRDLVGVEKAAHAGTLDPKVTGCLPVLTG  66

Query: 121 RATRLVKSQQSAGKEYVAVLRLHGMRPELDEATVRRAIETLTGPLYQRPPLISAVKRQLR 180
            ATR+  +     KEYVAVL LH   P +    +   IE  TG +YQ+PP  SAV R+LR
Sbjct:  67 TATRIAPALLEGFKEYVAVLELHDDPPRI----LPDVIEAFTGEIYQKPPKKSAVARRLR 122

Query: 181 IRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHS 240
            RT+Y+  +L+ D   R VL  + CE+GTYIR LC  +G  LG   HM  LRR  +    
Sbjct: 123 TRTVYDLDVLDVDG--RQVLLRIRCESGTYIRKLCHDIGRALGTNAHMGHLRRSATTPFD 180

Query: 241 EYDGMVTMHDVLDA-QWLFDTTKDE------SYLRRVIKPLESLLVHHKRIVIKDSCVNA 293
           + D +VT+HD+ DA  WL DT   E        LR  ++P E  L H  R+ I DS  + 
Sbjct: 181 DTD-LVTLHDLADAVAWLRDTDDTEPPDAPADALRAAVQPAERALTHLPRLTIADSAAHE 239

Query: 294 VCYGAKLMLPGVL 306
           V  GA +  PGV+
Sbjct: 240 VATGAPVYAPGVI 252

ref|YP_023445.1| tRNA pseudouridine 55 synthase [Picrophilus torridus DSM 9790]
gb|AAT43252.1| tRNA pseudouridine 55 synthase [Picrophilus torridus DSM 9790]
sp|Q6L1A0|TRUB_PICTO Probable tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(349 aa)

Score: 183 bits (465), Expect: 7.2609e-45
Length: 269, Idn/Pos/Gap = 98/157/7 (36%/58%/2%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           +G I +DKP  P+SH++ +WI+ I    + GH GTLDP V+G L++ + +AT+L+     
Sbjct:   5 NGFIVVDKPKGPTSHQIDSWIRDITGEPRVGHIGTLDPGVSGVLVMALGKATKLIDIVHR  64

Query: 132 AGKEYVAVLRLHGMRPELDEATVRRAIETLTGPLYQRPPLISAVKRQLRIRTIYESKLLE 191
             KEYV+VLR +    + D  +++   +  TG +YQ PP+ SAV R+LRIR IY  +LLE
Sbjct:  65 ESKEYVSVLRTYD---KYDHDSIKSVFKEFTGKIYQIPPVRSAVSRELRIREIYNLELLE 121

Query: 192 YDPKRRLVLFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDV 251
            D K   VLF V CE+GTYIRTLC  +G +LG GG M ELRR R+G   E     T+ +V
Sbjct: 122 MDEK--FVLFKVCCESGTYIRTLCTDIGYVLGSGGQMAELRRTRTGPFDE-SMCHTLQEV 178

Query: 252 LDAQWLFDTTKDESYLRRVIKPLESLLVHHKRIVIKDSCVNAVCYGAKLMLPGVLRYEND 311
            DA +   +  +E   + +  P++ + + + ++++K++ +  + +G+ +   G+      
Sbjct: 179 SDA-FKLKSMGNEKLFKNIFIPMDFIFIKYPKVIVKETALKNIAHGSDIYPAGIHAITGS 237

Query: 312 IECGEEVVIMTTKGEAVALAIAHMSTSEI 340
            + G+ V + T K E VA     ++  EI
Sbjct: 238 PKKGDVVAVYTEKNELVATGTMMVNADEI 266

gb|AAT12405.1| centromere/microtubule binding protein-like protein [Antonospora locustae]
(156 aa)

Score: 182 bits (461), Expect: 2.06037e-44
Length: 149, Idn/Pos/Gap = 83/116/1 (55%/77%/0%)

Query: 219 GLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPLESLL 278
           GLLLGV  HM++LRR+R+G  +EYD  VTMHD+LDA +L +T  DES +R+V +PLE LL
Sbjct:   1 GLLLGVEAHMKDLRRIRTGHFTEYDS-VTMHDILDAIYLLNTRGDESVVRKVFQPLEVLL  59

Query: 279 VHHKRIVIKDSCVNAVCYGAKLMLPGVLRYENDIECGEEVVIMTTKGEAVALAIAHMSTS 338
             +KRI++KDSCV A+C GA+L + G+++YE +IE G+E+V+MTTKGEAVALA A +S+ 
Sbjct:  60 KGYKRIMVKDSCVGALCAGAQLTINGIVKYEKEIEIGDEIVLMTTKGEAVALAAAKISSV 119

Query: 339 EIASCDHGVVARIKRVVMERDLYPRRWGL 367
           EI   +HG+V + KRV+M++ +YP  WG 
Sbjct: 120 EIGILEHGIVCKTKRVIMDKGVYPETWGF 148

sp|Q9HIT4|TRUB_THEAC Probable tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(365 aa)

Score: 181 bits (458), Expect: 5.0734e-44
Length: 269, Idn/Pos/Gap = 107/150/7 (39%/55%/2%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           +G + LDKP  P+SH+V  W++ IL +EK  H GTLDP VTG L + I +A RLV     
Sbjct:   7 NGFVVLDKPQGPTSHQVDHWVREILGIEKVAHIGTLDPNVTGVLTMAIGKAVRLVDVVHE  66

Query: 132 AGKEYVAVLRLHGMRPELDEATVRRAIETLTGPLYQRPPLISAVKRQLRIRTIYESKLLE 191
           + KEYV V+R +    ++ E  VR   +  TG +YQ PP+ SAV R LRI+T+Y   LLE
Sbjct:  67 SPKEYVGVMRFY---EDITEEEVRYYFKKFTGRIYQLPPVRSAVARSLRIKTVYSLDLLE 123

Query: 192 YDPKRRLVLFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDV 251
              K RLVLF V CE+GTYIRTLC  +G + G GG M +LRR  +G  SE D  +T+ D 
Sbjct: 124 --KKDRLVLFHVKCESGTYIRTLCTDIGYVSGKGGQMVDLRRTSTGPFSE-DRCITLQDF 180

Query: 252 LDAQWLFDTTKDESYLRRVIKPLESLLVHHKRIVIKDSCVNAVCYGAKLMLPGVLRYEND 311
                L    +D+  LR  I  +      + +IV+K S +  + +G+ L   G+   +  
Sbjct: 181 AAMVELARKGEDK-LLRDHILDMTYAFKDYPKIVVKRSAMRNIAHGSDLYAGGIKIIDGK 239

Query: 312 IECGEEVVIMTTKGEAVALAIAHMSTSEI 340
              GE V +++   + V   IA  S+  I
Sbjct: 240 FRKGERVAVISEDNDLVGTGIAMCSSDNI 268

gb|AAV48032.1| tRNA pseudouridine synthase B [Haloarcula marismortui ATCC 43049]
ref|YP_137738.1| tRNA pseudouridine synthase B [Haloarcula marismortui ATCC 43049]
sp|Q5UXH1|TRUB_HALMA Probable tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(314 aa)

Score: 178 bits (451), Expect: 3.07614e-43
Length: 302, Idn/Pos/Gap = 118/161/18 (39%/53%/5%)

Query:  61 PLKRPIQEYIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIE 120
           P +R +      GV+NLDKP  PS+H+V AWI+     ++  H GTLDP+VTGCL V + 
Sbjct:  25 PDERDLDSLRSFGVVNLDKPPGPSAHQVAAWIRDATGQDRVAHGGTLDPKVTGCLPVLLG  84

Query: 121 RATRLVKSQQSAGKEYVAVLRLHGMRPELDEATVRRAIETLTGPLYQRPPLISAVKRQLR 180
            A R+ +   +A KEYV VL LH   P  D A +    ET    +YQ+PP  SAVKRQLR
Sbjct:  85 DAARMAQVFDNAVKEYVTVLELHDQAPA-DIADIVAEFET---DIYQKPPRKSAVKRQLR 140

Query: 181 IRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHS 240
            R I+   +LE   +R  +L  V C +GTYIR LC  +GL  G G HM +LRR  +G   
Sbjct: 141 SRRIHSLDILEQGDRR--LLLRVRCASGTYIRKLCHDIGLAAGTGAHMGDLRRTATGTFD 198

Query: 241 EYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPLESLLVHHKRIVIKDSCVNAVCYGAKL 300
           +   + TMHD++DA   F    DE+ LR +I+P E  L H  R+ I  S    V  GA +
Sbjct: 199 D-GSLSTMHDLVDA-LAFAADGDEAQLREIIQPAERALSHLPRVTIAPSAAREVAEGAPV 256

Query: 301 MLPGVLRY------ENDIECGEEVVIMTTKGEAVALAIAHMSTSEIASCDHGVVARIKRV 354
             PGV+        +   E   +VV +T  G AV L     +       D G+V  + R+
Sbjct: 257 YAPGVIETGPAEVGDATPEIDSQVVSVTPDGAAVCLG----TLVSDPDADSGLVVELDRM 312

Query: 355 VM 356
           ++
Sbjct: 313 LV 314

ref|NP_376276.1| hypothetical centromere/microtubule binding protein cbf5 [Sulfolobus tokodaii str. 7]
sp|Q975L5|TRUB_SULTO Probable tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
dbj|BAB65385.1| 237aa long hypothetical centromere/microtubule binding protein cbf5 [Sulfolobus tokodaii str. 7]
(237 aa)

Score: 178 bits (451), Expect: 3.42858e-43
Length: 235, Idn/Pos/Gap = 89/153/7 (37%/65%/2%)

Query: 131 SAGKEYVAVLRLHGMRPELDEATVRRAIETLTGPLYQRPPLISAVKRQLRIRTIYESKLL 190
           S+GKEYV ++++H    + +   +++ I    G +YQ+PP+ S+VKR+ R + IY+ ++L
Sbjct:   6 SSGKEYVCLMQVHC---DFNIDELKQIISKFIGIIYQKPPVRSSVKRRTRKKKIYDIEIL  62

Query: 191 EYDPKRRLVLFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHD 250
           + D  +R +L  +S + GTY+R LC  +G++LG G HM+ELRR+RSG+ +E + +VT+ +
Sbjct:  63 DTD--KRFILLRISSDPGTYMRKLCHDIGVILGCGAHMRELRRIRSGIFTEKN-LVTLQE 119

Query: 251 VLDAQWLFDTTKDESYLRRVIKPLESLLVHHKRIVIKDSCVNAVCYGAKLMLPGVLRYEN 310
           + +A +++   KDES LR+++ P+E       +I+I D+ V+A+ YGA L  PG++ Y+ 
Sbjct: 120 ISEALYMWKNCKDESDLRKILLPMEYATCGMPKILIDDNAVDAISYGAMLTAPGIVAYQR 179

Query: 311 DIECGEEVVIMTTKGEAVALAIAHMSTSEIASCDHGVVARIKRVVMERDLYPRRW 365
                + V I+T KGE VA+  A + + ++     G+V + KRV+M RD+YPR W
Sbjct: 180 -FRVKDTVAILTLKGELVAIGEADVDSQKLVDMKKGIVVKPKRVLMPRDIYPRSW 233

ref|NP_394700.1| dyskerin (nucleolar protein Nap57) related protein [Thermoplasma acidophilum DSM 1728]
emb|CAC12368.1| dyskerin (nucleolar protein Nap57) related protein [Thermoplasma acidophilum]
(355 aa)

Score: 177 bits (449), Expect: 5.47064e-43
Length: 264, Idn/Pos/Gap = 106/147/7 (40%/55%/2%)

Query:  77 LDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAGKEY 136
           LDKP  P+SH+V  W++ IL +EK  H GTLDP VTG L + I +A RLV     + KEY
Sbjct:   2 LDKPQGPTSHQVDHWVREILGIEKVAHIGTLDPNVTGVLTMAIGKAVRLVDVVHESPKEY  61

Query: 137 VAVLRLHGMRPELDEATVRRAIETLTGPLYQRPPLISAVKRQLRIRTIYESKLLEYDPKR 196
           V V+R +    ++ E  VR   +  TG +YQ PP+ SAV R LRI+T+Y   LLE   K 
Sbjct:  62 VGVMRFY---EDITEEEVRYYFKKFTGRIYQLPPVRSAVARSLRIKTVYSLDLLE--KKD 116

Query: 197 RLVLFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQW 256
           RLVLF V CE+GTYIRTLC  +G + G GG M +LRR  +G  SE D  +T+ D      
Sbjct: 117 RLVLFHVKCESGTYIRTLCTDIGYVSGKGGQMVDLRRTSTGPFSE-DRCITLQDFAAMVE 175

Query: 257 LFDTTKDESYLRRVIKPLESLLVHHKRIVIKDSCVNAVCYGAKLMLPGVLRYENDIECGE 316
           L    +D+  LR  I  +      + +IV+K S +  + +G+ L   G+   +     GE
Sbjct: 176 LARKGEDK-LLRDHILDMTYAFKDYPKIVVKRSAMRNIAHGSDLYAGGIKIIDGKFRKGE 234

Query: 317 EVVIMTTKGEAVALAIAHMSTSEI 340
            V +++   + V   IA  S+  I
Sbjct: 235 RVAVISEDNDLVGTGIAMCSSDNI 258

gb|AAW24614.1| unknown [Schistosoma japonicum]
(176 aa)

Score: 176 bits (445), Expect: 1.44006e-42
Length: 124, Idn/Pos/Gap = 85/95/2 (68%/76%/1%)

Query:  20 IPSDAGENGLSTDSWPLLLKNYDRLNVRTTHYTPIPDAGYSPLKRPIQEYIRSGVINLDK  79
           IP D     L    WPLLLKN   +NVR  H+      G+SPL RP+ EYI+SGVINLDK
Sbjct:  27 IPEDKKPT-LDCSQWPLLLKNVHLMNVRECHFEA-DTTGFSPLHRPLDEYIKSGVINLDK  84

Query:  80 PANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAGKEYVAV 139
           P NPSSHEVVAW+KR L V KTGHSGTLDP+V+GCLIVCI+RATRLVKSQQSAGKEYV +
Sbjct:  85 PCNPSSHEVVAWVKRALGVNKTGHSGTLDPKVSGCLIVCIDRATRLVKSQQSAGKEYVCI 144

Query: 140 LRLH 143
            RLH
Sbjct: 145 FRLH 148

ref|ZP_00306685.1| COG0130: Pseudouridine synthase [Ferroplasma acidarmanus]
(351 aa)

Score: 170 bits (430), Expect: 9.25933e-41
Length: 260, Idn/Pos/Gap = 88/150/7 (33%/57%/2%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           +G I +DKP  P+SH++ AW++ I   ++ GH GTLDP V+G L++ + +AT+L+     
Sbjct:  12 NGFIVIDKPKGPTSHQIDAWVREITGEKRVGHIGTLDPNVSGVLVMALGKATKLIDIVHE  71

Query: 132 AGKEYVAVLRLHGMRPELDEATVRRAIETLTGPLYQRPPLISAVKRQLRIRTIYESKLLE 191
             KEY++V+RL+      D   + +  +  TG +YQ PP+ SAV RQ+R RTIY   +LE
Sbjct:  72 RPKEYISVMRLYSTA---DTDNIMKVFKEFTGKIYQLPPVRSAVSRQVRERTIYNMDVLE 128

Query: 192 YDPKRRLVLFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDV 251
              + +L+LF V CE+GTYIRTLC  +G ++G G  M +LRR+ +G  +E   + T+ ++
Sbjct: 129 I--QEKLILFRVKCESGTYIRTLCTDMGYVIGTGAQMADLRRLSTGQFNE-SHIHTLQEL 185

Query: 252 LDAQWLFDTTKDESYLRRVIKPLESLLVHHKRIVIKDSCVNAVCYGAKLMLPGVLRYEND 311
            D+  +     D S    ++ P++ +     ++V+K++ +  + +G+ +   G+     D
Sbjct: 186 SDSV-VLKKQGDTSLFDNMVIPMDFVFADSPKVVVKNTAIKNIMHGSDIYPSGIKALIGD 244

Query: 312 IECGEEVVIMTTKGEAVALA 331
           I  G  V I +   E +A  
Sbjct: 245 IHKGSRVAIYSGDNELLAFG 264

emb|CAH83896.1| hypothetical protein PC300741.00.0 [Plasmodium chabaudi]
(122 aa)

Score: 163 bits (412), Expect: 9.18772e-39
Length: 120, Idn/Pos/Gap = 73/99/1 (60%/82%/0%)

Query:  16 LSFQIPSDAGENGLSTDSWPLLLKNYDRLNVRTTHYTPIPDAGYSPLKRPIQEYIRSGVI  75
           + ++I  +  E  +   +WPLLLKNYD+LN+R++H+TP+P  G SP  R ++EY++ G+I
Sbjct:   4 VEYKIEPEKKEATIDASNWPLLLKNYDKLNIRSSHFTPLP-MGNSPYSRNLKEYLKYGII  62

Query:  76 NLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAGKE 135
           NLDKP+NPSSHEVV+WI++ILR EKTGHSGTLDP+VTG L+VC+ RATRLVKSQQ +GK+
Sbjct:  63 NLDKPSNPSSHEVVSWIRKILRCEKTGHSGTLDPKVTGVLLVCLNRATRLVKSQQESGKD 122

gb|EAA53241.1| hypothetical protein MG07518.4 [Magnaporthe grisea 70-15]
ref|XP_367607.1| hypothetical protein MG07518.4 [Magnaporthe grisea 70-15]
(184 aa)

Score: 151 bits (382), Expect: 3.52365e-35
Length: 97, Idn/Pos/Gap = 71/81/0 (73%/83%/0%)

Query: 301 MLPGVLRYENDIECGEEVVIMTTKGEAVALAIAHMSTSEIASCDHGVVARIKRVVMERDL 360
           MLPG+LRYE DIE  EEVV+MTTKGEA+A+ IA MST EI+SCDHGVVA++KR +MERDL
Sbjct:   1 MLPGLLRYEADIELHEEVVLMTTKGEAIAIGIAQMSTVEISSCDHGVVAKVKRCIMERDL  60

Query: 361 YPRRWGLGPVASRKKAMIQRGELDKHGRPNEHTPSDW 397
           YPRRWGLGPVA  KK +   G+LDK GRPNE TPS W
Sbjct:  61 YPRRWGLGPVAGEKKKLKADGKLDKFGRPNEATPSRW  97

emb|CAB13539.1| tRNA pseudouridine 55 synthase [Bacillus subtilis subsp. subtilis str. 168]
ref|NP_389548.1| tRNA pseudouridine 55 synthase [Bacillus subtilis subsp. subtilis str. 168]
sp|P32732|TRUB_BACSU tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(309 aa)

Score: 115 bits (287), Expect: 3.06743e-24
Length: 299, Idn/Pos/Gap = 90/140/47 (30%/46%/15%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           +GV+ L KP   +SH+ V  I+++L+ +K GH+GTLDP+V+G L +C+ RAT++V+    
Sbjct:   3 NGVLLLHKPVGMTSHDCVMKIRKLLKTKKVGHTGTLDPEVSGVLPICVGRATKIVEYLTE  62

Query: 132 AGKEYVAVLRL----------------HGMRPELDEATVRRAIETLTGPLYQRPPLISAV 175
             K Y A + L                  +  ++D+A V + + +L G   Q PP+ SAV
Sbjct:  63 KSKTYDAEITLGFSTTTEDQTGETVETKPVNHDIDKADVEKVLNSLKGKQEQIPPMYSAV 122

Query: 176 KRQLRIRTIYESKLLEYD-PKRRLVL-------------------FWVSCEAGTYIRTLC 215
           K   +    Y    +E + PKR + +                   F V+C  GTY+RTL 
Sbjct: 123 KVNGKKLYEYARAGIEVERPKRMITIEDIALTTEIKHHGETASFRFTVTCSKGTYVRTLA 182

Query: 216 VHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPLE 275
           V +G  LG   HM  L R  SG  S  D   T  D L+AQ    T ++ +       P+E
Sbjct: 183 VMIGEKLGYPAHMSHLIRTASGDFS-LDECFTF-DELEAQAQSGTVEEHTV------PIE 234

Query: 276 SLLVHHKRIVIKDSCVNAVCYGAKLMLPGVLRYENDIECGEEVVIMTTKGEAVALAIAH 334
             L H  + +I D+    V  GA L  P      +++  G+ + + T  G  +A+   H
Sbjct: 235 RALNHLPKWIISDTLAKKVENGALLETPEQF---SEMTSGDRIAVFTESGTCLAIYFPH 290

ref|ZP_00183605.2| COG0130: Pseudouridine synthase [Exiguobacterium sp. 255-15]
(302 aa)

Score: 113 bits (283), Expect: 8.70424e-24
Length: 270, Idn/Pos/Gap = 87/130/47 (32%/48%/17%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           GV+ LDKPA  +SH+ V  ++R+ + +K GH+GTLDP+VTG L +C+ RAT+L +     
Sbjct:   5 GVLPLDKPAGMTSHDCVFRLRRLFQTKKVGHTGTLDPEVTGVLPICLGRATKLARFITDE  64

Query: 133 GKEYVAVLRL---------HG--------MRPELDEATVRRAIETLTGPLYQRPPLISAV 175
           GK YVA + +         HG            + E  V   ++ LTG + Q PP  SAV
Sbjct:  65 GKRYVAEVTIGYATTTEDAHGETVRETPVTPASITEQQVDEILQQLTGQIEQTPPYYSAV 124

Query: 176 K--------------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLC 215
           K                    R ++I T+  +  L +          ++C  GTYIRTL 
Sbjct: 125 KVNGKKLYEYARKGIEVERPTRTVQIDTLERTSGLTFADGLCRFQIEIACGKGTYIRTLA 184

Query: 216 VHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPLE 275
           V +G  LG   HM ELRR  SG+ SE +  VT+  +   + +      E  ++ V+ P+E
Sbjct: 185 VEIGEQLGYAAHMSELRRTSSGMMSETEA-VTLATLEACETV------EERMQYVL-PIE 236

Query: 276 SLLVHHKRIVIKDSCVNAVCYGAKLMLPGV 305
            ++    R+ +       V  GAK  LPG+
Sbjct: 237 QVIQKWPRLTVNAETAARVLNGAK--LPGI 264

ref|YP_091479.1| TruB [Bacillus licheniformis ATCC 14580]
gb|AAU40786.1| TruB [Bacillus licheniformis DSM 13]
sp|Q65JH8|TRUB_BACLD tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(309 aa)

Score: 112 bits (279), Expect: 3.04283e-23
Length: 299, Idn/Pos/Gap = 92/139/47 (30%/46%/15%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           +GV+ L KP   +SH+ V  I+++L+ +K GH+GTLDP+V+G L +C+ RAT++V+    
Sbjct:   3 NGVLLLHKPVGMTSHDCVMKIRKLLKTKKVGHTGTLDPEVSGVLPICVGRATKIVEYLTE  62

Query: 132 AGKEYVAVLRL-------------HGMRPEL---DEATVRRAIETLTGPLYQRPPLISAV 175
             K Y A + L                +P L   DE TV+  + +L G + Q PP+ SAV
Sbjct:  63 KSKTYDAEVTLGCSTETEDQTGEVTEKKPVLAPPDEQTVQSVLRSLEGTIEQVPPMYSAV 122

Query: 176 K-----------------RQLRIRTIYESKL---LEYDPKRRLVLFWVSCEAGTYIRTLC 215
           K                 R  R  TI+  +L   + ++  +    F V+C  GTY+RTL 
Sbjct: 123 KVGGKKLYEYARAGIEVERPKRTITIHHIELTSEIRHEGDKARFRFVVTCSKGTYVRTLA 182

Query: 216 VHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPLE 275
           V +G  LG   HM  L R  SG  +  D  +T  DV     + D T  E  +     P+E
Sbjct: 183 VTIGEKLGYPAHMSNLVRTASGPFT-LDECLTFEDV--EGLIADGTLSEKLV-----PIE 234

Query: 276 SLLVHHKRIVIKDSCVNAVCYGAKLMLPGVLRYENDIECGEEVVIMTTKGEAVALAIAH 334
             L H  + +I D+    V  GA L  PG   +   +   + + + T  G   A+   H
Sbjct: 235 RALDHLPKWIISDTLAKKVENGAVLETPGSFSH---LTSEDRIAVFTEAGRCTAVYYPH 290

gb|AAU23426.1| tRNA pseudouridine 55 synthase [Bacillus licheniformis ATCC 14580]
ref|YP_079064.1| tRNA pseudouridine 55 synthase [Bacillus licheniformis ATCC 14580]
(309 aa)

Score: 111 bits (278), Expect: 3.36327e-23
Length: 299, Idn/Pos/Gap = 92/139/47 (30%/46%/15%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           +GV+ L KP   +SH+ V  I+++L+ +K GH+GTLDP+V+G L +C+ RAT++V+    
Sbjct:   3 NGVLLLHKPVGMTSHDCVMKIRKLLKTKKVGHTGTLDPEVSGVLPICVGRATKIVEYLTE  62

Query: 132 AGKEYVAVLRL-------------HGMRPEL---DEATVRRAIETLTGPLYQRPPLISAV 175
             K Y A + L                +P L   DE TV+  + +L G + Q PP+ SAV
Sbjct:  63 KSKTYDAEVTLGCSTETEDQTGEVTEKKPVLAPPDEQTVQSVLRSLEGTIEQVPPMYSAV 122

Query: 176 K-----------------RQLRIRTIYESKL---LEYDPKRRLVLFWVSCEAGTYIRTLC 215
           K                 R  R  TI+  +L   + ++  +    F V+C  GTY+RTL 
Sbjct: 123 KVGGKKLYEYARAGIEVERPKRTITIHHIELTSEIRHEGDKARFRFVVTCSKGTYVRTLA 182

Query: 216 VHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPLE 275
           V +G  LG   HM  L R  SG  +  D  +T  DV     + D T  E  +     P+E
Sbjct: 183 VTIGEKLGYPAHMSNLVRTASGPFT-LDECLTFEDV--EGLIADGTLSEKLV-----PIE 234

Query: 276 SLLVHHKRIVIKDSCVNAVCYGAKLMLPGVLRYENDIECGEEVVIMTTKGEAVALAIAH 334
             L H  + +I D+    V  GA L  PG   +   +   + + + T  G   A+   H
Sbjct: 235 RALDHLPKWIISDTLAKKVENGAVLETPGSFSH---LTSEDRIAVFTEAGRCTAVYYPH 290

ref|YP_147119.1| tRNA pseudouridine 5S synthase [Geobacillus kaustophilus HTA426]
sp|Q5L0I5|TRUB_GEOKA tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
dbj|BAD75551.1| tRNA pseudouridine 5S synthase [Geobacillus kaustophilus HTA426]
(285 aa)

Score: 111 bits (278), Expect: 4.07479e-23
Length: 272, Idn/Pos/Gap = 94/127/47 (34%/46%/17%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           GV+ L+KP   +SH+ VA ++R+L V+K GH+GTLDP V+G L +C+ +ATR+ +     
Sbjct:   3 GVLLLNKPKGMTSHDCVAKVRRLLGVKKAGHTGTLDPNVSGVLPICLGKATRIAEFLTGT  62

Query: 133 GKEYVAVLRLH-------------GMRPELDEATVRRAIE----TLTGPLYQRPPLISAV 175
            K Y   + L                RP +D    R  IE    +LTG + Q PP+ SAV
Sbjct:  63 TKTYEGKVTLGAATTTEDADGDIIAARP-VDRPIARAEIEAVFDSLTGEIEQTPPMYSAV 121

Query: 176 K-----------------RQLRIRTIYESKLL----EYDPKRRLVLFWVSCEAGTYIRTL 214
           K                 R  R  TIYE +LL    ++  +     F V+C  GTY+RTL
Sbjct: 122 KVGGKKLYEYARAGIEVERPTRRVTIYELELLDEREQFFGETVSFRFRVTCSKGTYVRTL 181

Query: 215 CVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPL 274
            V +G  LG   HM +L R  SG     D  VT  DV   +   D T D      ++ P+
Sbjct: 182 AVMIGERLGYPAHMSDLIRTASGPFRLED-CVTFEDV--ERRAADGTADA-----LLIPI 233

Query: 275 ESLLVHHKRIVIKDSCVNAVCYGAKLMLPGVL 306
           E  L H  +  I D     V  GA L LP  L
Sbjct: 234 ERALFHLPKYEINDKVAEKVKNGALLRLPAFL 265

ref|NP_345679.1| tRNA pseudouridine synthase B [Streptococcus pneumoniae TIGR4]
gb|AAK75319.1| tRNA pseudouridine synthase B [Streptococcus pneumoniae TIGR4]
sp|Q97QJ3|TRUB_STRPN tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(292 aa)

Score: 111 bits (277), Expect: 4.24838e-23
Length: 202, Idn/Pos/Gap = 73/97/36 (36%/48%/17%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           +G+INL K A  +SH+ V  +++IL  +K GH GTLDP V G L + + +ATR+V+  Q 
Sbjct:   2 NGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGVLPIAVGKATRMVEFMQD  61

Query: 132 AGKEYVAVLRL-HGMRPE---------------LDEATVRRAIETLTGPLYQRPPLISAV 175
            GK Y   + L +  + E               LDE  V  AI +LTGP+ Q PP+ SAV
Sbjct:  62 EGKIYEGEITLGYSTKTEDASGEVVAETPVLSLLDEKLVDEAIASLTGPITQIPPMYSAV 121

Query: 176 K--------------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLC 215
           K                    RQ+ I     +  + YD +     F V C  GTYIRTL 
Sbjct: 122 KVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDGQLARFTFRVKCSKGTYIRTLS 181

Query: 216 VHLGLLLGVGGHMQELRRVRSG 237
           V LG  LG   HM  L R  + 
Sbjct: 182 VDLGEKLGYAAHMSHLTRTSAA 203

ref|ZP_00322432.1| COG0130: Pseudouridine synthase [Pediococcus pentosaceus ATCC 25745]
(299 aa)

Score: 110 bits (275), Expect: 8.77971e-23
Length: 284, Idn/Pos/Gap = 84/132/51 (29%/46%/17%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           G+I ++K    +SH+VVA ++ ILR +K GHSGTLDP V G L +C+ RAT++V      
Sbjct:   3 GIIPINKERGMTSHDVVAKVRGILRTKKVGHSGTLDPSVDGVLPICVGRATKVVDYLMGF  62

Query: 133 GKEYVA----------------VLRLHGMRPELDEATVRRAIETLTGPLYQRPPLISAVK 176
           GK Y                  V+    +   L +  + + +  +TG L Q PP+ SAVK
Sbjct:  63 GKVYQGSITLGFSTTTEDLDGEVVETKKLDEPLTDEQINQTLTAMTGTLIQIPPMYSAVK 122

Query: 177 --------------------RQLRIRTIYESKLLEYDPKR--RLVLFWVSCEAGTYIRTL 214
                               RQ+++    +++   +D ++  + + F VSC  GTY+RTL
Sbjct: 123 VKGRKLYEYARAGETVERPQRQIKVYDFVQTRPSIFDAEKGQQTIYFKVSCGKGTYVRTL 182

Query: 215 CVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPL 274
            V  G   G+   M +L R+ SG   + +  +T+ D+       +  +DE  L  VI+PL
Sbjct: 183 AVDFGRHFGLPAVMSDLSRLASGGF-KIEECLTLSDL-------EQARDEDRLSTVIQPL 234

Query: 275 ESLLVHHKRIVIKDSCVNAVCYGAKLMLPGV-----LRYENDIE 313
           +  L +   I I D     V  G  L  P       L+Y  +I+
Sbjct: 235 DRALDNFNTITISDVEWEIVKNGGFLNRPQTDEIIALKYNGNIQ 278

ref|YP_141388.1| tRNA pseudouridine synthase B [Streptococcus thermophilus CNRZ1066]
gb|AAV62573.1| tRNA pseudouridine synthase B [Streptococcus thermophilus CNRZ1066]
sp|Q5LZV2|TRUB_STRT1 tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(293 aa)

Score: 110 bits (274), Expect: 1.09981e-22
Length: 202, Idn/Pos/Gap = 71/99/37 (35%/49%/18%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           SG+INL K A  +SH+ V  +++IL  +K GH GTLDP VTG L + + +ATR+++    
Sbjct:   3 SGIINLKKEAGMTSHDAVFKLRKILHEKKIGHGGTLDPDVTGVLPIAVGKATRVIEYMTE  62

Query: 132 AGKEYVAVLRLHGMR----------------PELDEATVRRAIETLTGPLYQRPPLISAV 175
           AGK Y   + + G                   ELD ATV +A+ +  G + Q PP+ SAV
Sbjct:  63 AGKVYEGEITI-GFSTTTEDASGEVVQTTPITELDGATVDQAMASFEGEITQIPPMYSAV 121

Query: 176 K--------------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLC 215
           K                    RQ++I     +  +E +       F V+C  GTY+RTL 
Sbjct: 122 KINGKKLYEYARAGEEVERPQRQVKITEFVRTSPIELENGTARFTFRVACSKGTYVRTLS 181

Query: 216 VHLGLLLGVGGHMQELRRVRSG 237
           V LG+ LG   HM  LRR  S 
Sbjct: 182 VDLGVKLGFASHMSALRRTASA 203

ref|ZP_00388857.1| COG0130: Pseudouridine synthase [Streptococcus thermophilus LMD-9]
(293 aa)

Score: 110 bits (274), Expect: 1.14667e-22
Length: 202, Idn/Pos/Gap = 71/99/37 (35%/49%/18%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           SG+INL K A  +SH+ V  +++IL  +K GH GTLDP VTG L + + +ATR+++    
Sbjct:   3 SGIINLKKEAGMTSHDAVFKLRKILHEKKIGHGGTLDPDVTGVLPIAVGKATRVIEYMTE  62

Query: 132 AGKEYVAVLRLHGMR----------------PELDEATVRRAIETLTGPLYQRPPLISAV 175
           AGK Y   + + G                   ELD ATV +A+ +  G + Q PP+ SAV
Sbjct:  63 AGKVYEGEITI-GFSTTTEDASGEVVQTTPITELDGATVDQAMASFEGEITQIPPMYSAV 121

Query: 176 K--------------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLC 215
           K                    RQ++I     +  +E +       F V+C  GTY+RTL 
Sbjct: 122 KINGKKLYEYARAGEEVERPQRQVKITEFVRTSPIELENGTARFTFRVACSKGTYVRTLS 181

Query: 216 VHLGLLLGVGGHMQELRRVRSG 237
           V LG+ LG   HM  LRR  S 
Sbjct: 182 VDLGVKLGFASHMSALRRTASA 203

ref|YP_139470.1| tRNA pseudouridine synthase B [Streptococcus thermophilus LMG 18311]
sp|Q5M4G2|TRUB_STRT2 tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
gb|AAV60655.1| tRNA pseudouridine synthase B [Streptococcus thermophilus LMG 18311]
(293 aa)

Score: 109 bits (273), Expect: 1.22582e-22
Length: 202, Idn/Pos/Gap = 71/99/37 (35%/49%/18%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           SG+INL K A  +SH+ V  +++IL  +K GH GTLDP VTG L + + +ATR+++    
Sbjct:   3 SGIINLKKEAGMTSHDAVFKLRKILHEKKIGHGGTLDPDVTGVLPIAVGKATRVIEYMTE  62

Query: 132 AGKEYVAVLRLHGMR----------------PELDEATVRRAIETLTGPLYQRPPLISAV 175
           AGK Y   + + G                   ELD ATV +A+ +  G + Q PP+ SAV
Sbjct:  63 AGKVYEGEITI-GFSTTTEDASGEVVQTTPITELDGATVDQAMASFEGEITQIPPMYSAV 121

Query: 176 K--------------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLC 215
           K                    RQ++I     +  +E +       F V+C  GTY+RTL 
Sbjct: 122 KINGKKLYEYARAGEEVERPQRQVKITEFVRTSPIELENGTARFTFRVACSKGTYVRTLS 181

Query: 216 VHLGLLLGVGGHMQELRRVRSG 237
           V LG+ LG   HM  LRR  S 
Sbjct: 182 VDLGVKLGFASHMSALRRTASA 203

emb|CAB84815.1| tRNA pseudouridine synthase B [Neisseria meningitidis Z2491]
sp|Q9JTX5|TRUB_NEIMA tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
ref|NP_284303.1| tRNA pseudouridine synthase B [Neisseria meningitidis Z2491]
(306 aa)

Score: 109 bits (273), Expect: 1.44844e-22
Length: 302, Idn/Pos/Gap = 88/133/53 (29%/44%/17%)

Query:  61 PLKRPIQEYIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIE 120
           P KRP+     +GV+ LDKP   SS+  +   + + R EK GH+G LDP  TG L VC  
Sbjct:   5 PAKRPV-----NGVLLLDKPEGLSSNTALQKTRHLFRAEKAGHTGVLDPLATGLLPVCFG  59

Query: 121 RATRLVKSQQSAGKEYVAVLRL--------------HGMRPELDEATVRRAIETLTGPLY 166
            AT+  +   +A K Y A L+L                 R ++  A  + A + LTG + 
Sbjct:  60 EATKFAQYLINADKAYTATLKLGEASSTGDAEGEIVATARADISLAEFQTACQALTGNIR 119

Query: 167 QRPPLISAVK-----------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGT 209
           Q PP+ SA+K                 R+ R  T+Y   + E+D  + ++   V C  GT
Sbjct: 120 QVPPMFSALKHEGKPLYEYARKGIVIERKARDITVYAIDIAEFDAPKAVID--VRCSKGT 177

Query: 210 YIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRR 269
           YIRTL   +   +G   H+  LRR  +   +     +     L+A    D T+ +S L  
Sbjct: 178 YIRTLSEDIAKHIGTFAHLTALRRTETAGFT-----IAQSHTLEALANLDETERDSLLL- 231

Query: 270 VIKPLESLLVHHKRIVIKDSCVNAVCYGAKLMLPGVLRYENDIECGEEVVIMTTKGEAVA 329
              P + L+ H  + V+ D  V+ +  G +       R+E D+     V + T  G  V 
Sbjct: 232 ---PCDVLVAHFPQTVLNDYAVHMLRCGQR------PRFEEDLPSDTPVRVYTENGRFVG 282

Query: 330 LA 331
           LA
Sbjct: 283 LA 284

ref|NP_358685.1| tRNA pseudouridine 5S synthase [Streptococcus pneumoniae R6]
gb|AAK99895.1| tRNA pseudouridine 5S synthase [Streptococcus pneumoniae R6]
sp|Q8CWR2|TRUB_STRR6 tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(292 aa)

Score: 108 bits (271), Expect: 2.14393e-22
Length: 202, Idn/Pos/Gap = 72/95/36 (35%/47%/17%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           +G+INL K A  +SH+ V  +++IL  +K GH GTLDP V G L + + +ATR+V+  Q 
Sbjct:   2 NGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGVLPIAVGKATRMVEFMQD  61

Query: 132 AGKEYVA----------------VLRLHGMRPELDEATVRRAIETLTGPLYQRPPLISAV 175
            GK Y                  V+    +   LDE  V  AI +LTGP+ Q PP+ SAV
Sbjct:  62 EGKIYEGEIILGYSTTTEDASGEVVAETPVLSSLDEKLVDEAIASLTGPITQIPPMYSAV 121

Query: 176 K--------------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLC 215
           K                    RQ+ I     +  + YD +     F V C  GTYIRTL 
Sbjct: 122 KVNGRKLYEYARAGQEVERPERQVIIYQFERTSPISYDGQLARFTFRVKCSKGTYIRTLS 181

Query: 216 VHLGLLLGVGGHMQELRRVRSG 237
           V LG  LG   HM  L R  + 
Sbjct: 182 VDLGEKLGYAAHMSHLTRTSAA 203

emb|CAD46692.1| Unknown [Streptococcus agalactiae NEM316]
ref|NP_735482.1| hypothetical protein gbs1033 [Streptococcus agalactiae NEM316]
ref|NP_688009.1| tRNA pseudouridine synthase B [Streptococcus agalactiae 2603V/R]
gb|AAM99881.1| tRNA pseudouridine synthase B [Streptococcus agalactiae 2603V/R]
sp|P65857|TRUB_STRA5 tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
sp|P65856|TRUB_STRA3 tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(294 aa)

Score: 108 bits (269), Expect: 4.11012e-22
Length: 210, Idn/Pos/Gap = 70/101/51 (33%/48%/24%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           +G+INL K A  +SH+ V  +++IL  +K GH GTLDP V G L + + +ATR+++    
Sbjct:   3 TGIINLKKEAGMTSHDAVFKLRKILHTKKIGHGGTLDPDVVGVLPIAVGKATRVIEYMTE  62

Query: 132 AGKEYVA-----------------VLRLHGMRPELDEATVRRAIETLTGPLYQRPPLISA 174
           +GK Y                   + R    + +L E  V  A+++ TGP+ Q PP+ SA
Sbjct:  63 SGKIYEGEITLGYATSTEDSSGEVISRTPLTQSDLSEDVVDHAMKSFTGPITQVPPMYSA 122

Query: 175 VKRQLRIRTIYESKLLEY--------DPKRRLVL-------------------FWVSCEA 207
           VK       +   KL EY         PKR++ +                   F+VSC  
Sbjct: 123 VK-------VNGKKLYEYARSGEEVERPKRQITISEFRRTSPLYFEKGICRFSFYVSCSK 175

Query: 208 GTYIRTLCVHLGLLLGVGGHMQELRRVRSG 237
           GTY+RTL V LG+ LG   HM  L+R  S 
Sbjct: 176 GTYVRTLAVDLGIKLGYASHMSFLKRTSSA 205

ref|YP_075354.1| tRNA pseudouridine 55 synthase [Symbiobacterium thermophilum IAM 14863]
dbj|BAD40510.1| tRNA pseudouridine 55 synthase [Symbiobacterium thermophilum IAM 14863]
sp|Q67P83|TRUB_SYMTH tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(299 aa)

Score: 107 bits (268), Expect: 5.14865e-22
Length: 198, Idn/Pos/Gap = 74/98/33 (37%/49%/16%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           GV+NL KP   +SH+VVA+++R L V+K GH+GTLDP V G L VC+ RATRL +    +
Sbjct:  14 GVLNLLKPPGMTSHDVVAFVRRALGVKKAGHTGTLDPGVAGVLPVCVGRATRLAEYIAGS  73

Query: 133 GKEYVAVLRL---------------HGMRPELDEATVRRAIETLTGPLYQRPPLISAVK- 176
            K Y A +                       L    V  A+    GP+ Q PP++SAVK 
Sbjct:  74 DKAYRAEITFGVATDTQDGFGEVVAEADASHLTRGDVAYALTRFHGPIEQVPPMVSAVKV 133

Query: 177 ----------------RQLRIRTIYESKLLEYDPKRRLVLFW-VSCEAGTYIRTLCVHLG 219
                           R+ R   I+  +LL++ P  R V +  V C  GTY+RTL   LG
Sbjct: 134 GGKRLYELARKGVEVEREPRRVFIHRLQLLDFRPGPRPVAYIDVVCSKGTYVRTLAHDLG 193

Query: 220 LLLGVGGHMQELRRVRSG 237
             L VG H+  L R RSG
Sbjct: 194 RFLQVGAHLSYLVRTRSG 211

gb|AAX77881.1| unknown protein [synthetic construct]
(337 aa)

Score: 106 bits (265), Expect: 1.07294e-21
Length: 247, Idn/Pos/Gap = 77/122/41 (31%/49%/16%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           +GV+ ++K  + SS++V+  +K +   +K GH+GTLDP  TG L +C  RAT++ +    
Sbjct:  35 NGVVVINKVKDISSNKVLQQLKYLFNAQKAGHTGTLDPMATGVLPICFGRATKIAQYLLD  94

Query: 132 AGKEYVAVLRLHGMR-----------------PELDEATVRRAIETLTGPLYQRPPLISA 174
           A KEY+A +RL G+                  PEL    +   +    G + Q PP+ SA
Sbjct:  95 ADKEYIATIRL-GIETDSGDAEGEIIAKSINIPELSAEYLETVLAKFRGDVVQIPPMYSA 153

Query: 175 VK-------------RQLRIRT----IYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVH 217
           +K             + + +++    IYE +LLE++     +   V C  GTYIR+L + 
Sbjct: 154 LKYNGQPLYKLAREGKTVEVKSRNIKIYELELLEFNIDSLKIR--VKCSKGTYIRSLAID 211

Query: 218 LGLLLGVGGHMQELRRVRSGVH--SEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPLE 275
           +G  LG GGH+  L+R +SG    SE   +  + D+   Q +   T  ES    + KP+ 
Sbjct: 212 IGKTLGCGGHLIALQRTQSGPFKLSEAFRLEQLKDLSFEQKIASITNIESVF--IDKPIY 269

Query: 276 SLLVHHK 282
           SLL   K
Sbjct: 270 SLLEEEK 276

ref|YP_170478.1| tRNA pseudouridine synthetase B [Francisella tularensis subsp. tularensis Schu 4]
emb|CAG46187.1| tRNA pseudouridine synthetase B [Francisella tularensis subsp. tularensis SCHU S4]
sp|Q5NER4|TRUB_FRATT tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(302 aa)

Score: 106 bits (265), Expect: 1.07294e-21
Length: 247, Idn/Pos/Gap = 77/122/41 (31%/49%/16%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           +GV+ ++K  + SS++V+  +K +   +K GH+GTLDP  TG L +C  RAT++ +    
Sbjct:   9 NGVVVINKVKDISSNKVLQQLKYLFNAQKAGHTGTLDPMATGVLPICFGRATKIAQYLLD  68

Query: 132 AGKEYVAVLRLHGMR-----------------PELDEATVRRAIETLTGPLYQRPPLISA 174
           A KEY+A +RL G+                  PEL    +   +    G + Q PP+ SA
Sbjct:  69 ADKEYIATIRL-GIETDSGDAEGEIIAKSINIPELSAEYLETVLAKFRGDVVQIPPMYSA 127

Query: 175 VK-------------RQLRIRT----IYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVH 217
           +K             + + +++    IYE +LLE++     +   V C  GTYIR+L + 
Sbjct: 128 LKYNGQPLYKLAREGKTVEVKSRNIKIYELELLEFNIDSLKIR--VKCSKGTYIRSLAID 185

Query: 218 LGLLLGVGGHMQELRRVRSGVH--SEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPLE 275
           +G  LG GGH+  L+R +SG    SE   +  + D+   Q +   T  ES    + KP+ 
Sbjct: 186 IGKTLGCGGHLIALQRTQSGPFKLSEAFRLEQLKDLSFEQKIASITNIESVF--IDKPIY 243

Query: 276 SLLVHHK 282
           SLL   K
Sbjct: 244 SLLEEEK 250

ref|YP_013943.1| tRNA pseudouridine synthase B [Listeria monocytogenes str. 4b F2365]
sp|Q71ZZ4|TRUB_LISMF tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
gb|AAT04120.1| tRNA pseudouridine synthase B [Listeria monocytogenes str. 4b F2365]
(304 aa)

Score: 106 bits (265), Expect: 1.29992e-21
Length: 280, Idn/Pos/Gap = 90/135/53 (32%/48%/18%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           +G+I L K    +SH+ V  +++IL  +K GH+GTLDP+V G L +CI RAT+L +    
Sbjct:   2 NGIIPLWKERGMTSHDCVFKLRKILHTKKVGHTGTLDPEVEGVLPICIGRATKLAEYVTD  61

Query: 132 AGKEYVAVLRLHGMRPELDEAT----------------VRRAIETLTGPLYQRPPLISAV 175
            GK YVA + L G     ++AT                ++ A+  LTG + Q PP+ SAV
Sbjct:  62 EGKVYVAEITL-GKSTTTEDATGETVMTKELADISADELQAALTKLTGKITQIPPMFSAV 120

Query: 176 K--------------------RQLRIRTIY----ESKLLEYDPKRRLVLFWVSCEAGTYI 211
           K                    RQ+ I ++     E+ L E +P  +L    +SC  GTYI
Sbjct: 121 KVNGKKLYEYARAGIEVERPSRQVDIYSLTRLNGEATLNEANPTFQLE---ISCGKGTYI 177

Query: 212 RTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVI 271
           RTL V +G LLG   HM +L R RSG   + D + T+ ++ +         D S+L  + 
Sbjct: 178 RTLAVMIGELLGYPAHMSKLERTRSGFFKKEDCL-TLAEIDEMM----QASDSSFLYPLE 232

Query: 272 KPLESLLVHHKRIVIKDSCVNAVCYGAKLMLPGVLRYEND 311
           K +ES+     ++VI +     V  G  L     +  EN+
Sbjct: 233 KGIESM----AKLVIDEEIHAKVLNGGLLPKSLFIEVENE 268

ref|ZP_00231844.1| tRNA pseudouridine synthase B [Listeria monocytogenes str. 4b H7858]
gb|EAL08316.1| tRNA pseudouridine synthase B [Listeria monocytogenes str. 4b H7858]
(304 aa)

Score: 106 bits (264), Expect: 1.54887e-21
Length: 246, Idn/Pos/Gap = 83/123/49 (33%/50%/19%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           +G+I L K    +SH+ V  +++IL  +K GH+GTLDP+V G L +CI RAT+L +    
Sbjct:   2 NGIIPLWKERGMTSHDCVFKLRKILHTKKVGHTGTLDPEVEGVLPICIGRATKLAEYVTD  61

Query: 132 AGKEYVAVLRLHGMRPELDEAT----------------VRRAIETLTGPLYQRPPLISAV 175
            GK YVA + L G     ++AT                ++ A+  LTG + Q PP+ SAV
Sbjct:  62 EGKVYVAEITL-GKSTTTEDATGETVMTKELADISADELQAALTKLTGKITQIPPMFSAV 120

Query: 176 K--------------------RQLRIRTIY----ESKLLEYDPKRRLVLFWVSCEAGTYI 211
           K                    RQ+ I ++     E+ L E +P  +L    +SC  GTYI
Sbjct: 121 KVNGKKLYEYARAGIEVERPSRQVDIYSLTRLDGEATLNEANPTFQLE---ISCGKGTYI 177

Query: 212 RTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVI 271
           RTL V +G LLG   HM +L R RSG   + D + T+ ++ +         D S+L  + 
Sbjct: 178 RTLAVMIGELLGYPAHMSKLERTRSGFFKKEDCL-TLAEIDEMM----QASDSSFLYPLE 232

Query: 272 KPLESL 277
           K +ES+
Sbjct: 233 KGIESM 238

ref|NP_470701.1| truB [Listeria innocua Clip11262]
emb|CAC96596.1| truB [Listeria innocua]
sp|Q92C26|TRUB_LISIN tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(304 aa)

Score: 104 bits (260), Expect: 3.94332e-21
Length: 212, Idn/Pos/Gap = 76/106/44 (35%/50%/20%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           +G+I L K    +SH+ V  +++IL  +K GH+GTLDP+V G L +CI RAT+L +    
Sbjct:   2 NGIIPLWKERGMTSHDCVFKLRKILHTKKVGHTGTLDPEVEGVLPICIGRATKLAEYVTD  61

Query: 132 AGKEYVAVLRLHGMRPELDEAT----------------VRRAIETLTGPLYQRPPLISAV 175
            GK YVA + L G     ++AT                ++ A+  LTG + Q PP+ SAV
Sbjct:  62 EGKVYVAEITL-GKSTTTEDATGETVATKELAEISAEELQAALTKLTGKITQIPPMFSAV 120

Query: 176 K--------------------RQLRIRTIYE----SKLLEYDPKRRLVLFWVSCEAGTYI 211
           K                    RQ+ I ++      S L E +P  +L    +SC  GTYI
Sbjct: 121 KVNGKKLYEYARAGIEVERPSRQVDIYSLVRLDGVSPLTESNPTFKLE---ISCGKGTYI 177

Query: 212 RTLCVHLGLLLGVGGHMQELRRVRSGVHSEYD 243
           RTL V +G LLG   HM +L R RSG   + D
Sbjct: 178 RTLAVMIGELLGYPAHMSKLERTRSGFFKKED 209

ref|ZP_00233516.1| tRNA pseudouridine synthase B [Listeria monocytogenes str. 1/2a F6854]
gb|EAL06589.1| tRNA pseudouridine synthase B [Listeria monocytogenes str. 1/2a F6854]
(304 aa)

Score: 104 bits (260), Expect: 4.11131e-21
Length: 281, Idn/Pos/Gap = 88/136/53 (31%/48%/18%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           +G+I L K    +SH+ V  +++IL  +K GH+GTLDP+V G L +CI RAT+L +    
Sbjct:   2 NGIIPLWKERGMTSHDCVFKLRKILHTKKVGHTGTLDPEVEGVLPICIGRATKLAEYVTD  61

Query: 132 AGKEYVAVLRLHGMR---------------PELDEATVRRAIETLTGPLYQRPPLISAVK 176
            GK YVA + L                    E+  A ++ A+  LTG + Q PP+ SAVK
Sbjct:  62 EGKVYVAEITLGKSTTTEDATGETVNTKELAEISAAELQAALTKLTGKITQIPPMFSAVK 121

Query: 177 --------------------RQLRIRTIY----ESKLLEYDPKRRLVLFWVSCEAGTYIR 212
                               RQ+ I ++     ++ L + +P  +L    ++C  GTYIR
Sbjct: 122 VNGKKLYEYARAGIEVERPSRQVDIYSLIRLDGDTALNQSNPTFQLE---IACGKGTYIR 178

Query: 213 TLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIK 272
           TL V +G LLG   HM +L R RSG   + D + T+ ++ +         D S+L  + K
Sbjct: 179 TLAVMIGELLGYPAHMSKLERTRSGFFKKEDCL-TLTEIDEMM----QASDSSFLYPLEK 233

Query: 273 PLESLLVHHKRIVIKDSCVNAVCYGAKLMLPGVLRYENDIE 313
            +ES+     ++VI++     V  G   +LP  L  E + E
Sbjct: 234 GIESM----AKLVIEEEVYAKVLNGG--LLPTSLFAEVENE 268

gb|AAF41748.1| tRNA pseudouridine synthase B [Neisseria meningitidis MC58]
sp|Q9JYY1|TRUB_NEIMB tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
ref|NP_274392.1| tRNA pseudouridine synthase B [Neisseria meningitidis MC58]
(307 aa)

Score: 104 bits (260), Expect: 4.21552e-21
Length: 302, Idn/Pos/Gap = 86/131/53 (28%/43%/17%)

Query:  61 PLKRPIQEYIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIE 120
           P KR +     +GV+ LDKP   SS+  +   +R+   EK GH+G LDP  TG L VC  
Sbjct:   6 PQKRAV-----NGVLLLDKPEGLSSNTALQKARRLFHAEKAGHTGVLDPLATGLLPVCFG  60

Query: 121 RATRLVKSQQSAGKEYVAVLRL--------------HGMRPELDEATVRRAIETLTGPLY 166
            AT+  +    A K Y A L+L                 R ++  A  + A + LTG + 
Sbjct:  61 EATKFAQYLLDADKAYTATLKLGEASSTGDAEGEIIATARADISLAEFQTACQALTGNIR 120

Query: 167 QRPPLISAVK-----------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGT 209
           Q PP+ SA+K                 R+ R  T+Y   + E+D  + ++   V C  GT
Sbjct: 121 QVPPMFSALKHEGKPLYEYARKGIVIERKARYITVYAIDIAEFDAPKAVID--VRCSKGT 178

Query: 210 YIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRR 269
           YIRTL   +   +G   H+  LRR  +   +     +     L+A    + T+ +S L  
Sbjct: 179 YIRTLSEDIAKHIGTFAHLTALRRTETAGFT-----IAQSHTLEALANLNETERDSLLL- 232

Query: 270 VIKPLESLLVHHKRIVIKDSCVNAVCYGAKLMLPGVLRYENDIECGEEVVIMTTKGEAVA 329
              P + L+ H  + V+ D  V+ +  G +       R+E D+     V + T  G  V 
Sbjct: 233 ---PCDVLVSHFPQTVLNDYAVHMLHCGQR------PRFEEDLPSDTPVRVYTENGRFVG 283

Query: 330 LA 331
           LA
Sbjct: 284 LA 285

ref|NP_738482.1| putative tRNA pseudouridine synthase B [Corynebacterium efficiens YS-314]
dbj|BAC18682.1| putative tRNA pseudouridine synthase B [Corynebacterium efficiens YS-314]
(327 aa)

Score: 104 bits (260), Expect: 4.58235e-21
Length: 216, Idn/Pos/Gap = 75/106/43 (34%/49%/19%)

Query:  59 YSPLKRPIQEYIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVC 118
           +S +  P+Q    SG++ +DKPA  +SH+VV+ ++R     K GH+GTLDP  TG L+V 
Sbjct:  28 FSGMNDPVQN---SGLVVVDKPAGMTSHDVVSKLRRAFSTRKVGHAGTLDPMATGVLVVG  84

Query: 119 IERATRLVKSQQSAGKEYVAVLRLHGMR---------------PELDEATVRRAIETLTG 163
           IER TR +    +  K Y A +RL                     LD+  +  A+ +LTG
Sbjct:  85 IERGTRFLAHLVATTKAYDATIRLGASTTTDDREGDVVFSADASTLDDEQITTAVTSLTG 144

Query: 164 PLYQRPPLISAVK-----RQLRIR------------TIYESKLLEYDPKRRLVLF----- 201
            + Q+P  +SA+K        R+R            T+    +LE   +RR   F     
Sbjct: 145 EIMQKPASVSAIKIDGKRAHERVRDGEVVDIPARPVTVSVFDVLE---QRREGGFVDLDV 201

Query: 202 WVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSG 237
            V C +GTYIR+L   LG  LGVGGH+  LRR   G
Sbjct: 202 RVHCSSGTYIRSLARDLGAALGVGGHLTALRRTEVG 237

ref|NP_464853.1| hypothetical protein lmo1328 [Listeria monocytogenes EGD-e]
emb|CAC99406.1| truB [Listeria monocytogenes]
sp|Q8Y7F3|TRUB_LISMO tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(304 aa)

Score: 104 bits (260), Expect: 4.73786e-21
Length: 281, Idn/Pos/Gap = 88/136/53 (31%/48%/18%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           +G+I L K    +SH+ V  +++IL  +K GH+GTLDP+V G L +CI RAT+L +    
Sbjct:   2 NGIIPLWKERGMTSHDCVYKLRKILHTKKVGHTGTLDPEVEGVLPICIGRATKLAEYVTD  61

Query: 132 AGKEYVAVLRLHGMR---------------PELDEATVRRAIETLTGPLYQRPPLISAVK 176
            GK YVA + L                    E+  A ++ A+  LTG + Q PP+ SAVK
Sbjct:  62 EGKVYVAEITLGKSTTTEDATGETVNTKELAEISAAELQAALTKLTGKITQIPPMFSAVK 121

Query: 177 --------------------RQLRIRTIY----ESKLLEYDPKRRLVLFWVSCEAGTYIR 212
                               RQ+ I ++     ++ L + +P  +L    ++C  GTYIR
Sbjct: 122 VNGKKLYEYARAGIEVERPSRQVDIYSLIRLDGDTALNQSNPTFQLE---IACGKGTYIR 178

Query: 213 TLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIK 272
           TL V +G LLG   HM +L R RSG   + D + T+ ++ +         D S+L  + K
Sbjct: 179 TLAVMIGELLGYPAHMSKLERTRSGFFKKEDCL-TLTEIDEMM----QASDSSFLYPLEK 233

Query: 273 PLESLLVHHKRIVIKDSCVNAVCYGAKLMLPGVLRYENDIE 313
            +ES+     ++VI++     V  G   +LP  L  E + E
Sbjct: 234 GIESM----AKLVIEEEVYAKVLNGG--LLPTSLFAEVENE 268

ref|NP_692522.1| tRNA-pseudouridine 5S synthase [Oceanobacillus iheyensis HTE831]
sp|Q8CXG9|TRUB_OCEIH tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
dbj|BAC13557.1| tRNA-pseudouridine 5S synthase [Oceanobacillus iheyensis HTE831]
(303 aa)

Score: 104 bits (259), Expect: 6.56001e-21
Length: 264, Idn/Pos/Gap = 81/123/43 (30%/46%/16%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           G++ L KP   +SH+ V   +R  + +K GH+GTLDP+V G L +CI +AT++V      
Sbjct:   3 GILPLWKPKGLTSHDCVMRCRRYFKTKKVGHTGTLDPEVEGVLPICIGQATKIVPFLTDT  62

Query: 133 GKEYVAVLRLHGMRPELDEAT-----------------VRRAIETLTGPLYQRPPLISAV 175
            K Y A ++L G   E ++AT                 +   ++T  G   Q PP+ SAV
Sbjct:  63 KKVYEATVQL-GYSTETEDATGKIVETKEVSDFPTNKNLEEVLQTFIGRTKQIPPMYSAV 121

Query: 176 K-----------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHL 218
           K                 R +R   I+E  L   D K       + C  GTYIRTLCV +
Sbjct: 122 KVNGKKLYEYARANESVERPVREIEIFELTLTSVDEKNHSFDIRIVCSKGTYIRTLCVDI 181

Query: 219 GLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPLESLL 278
           G  LG   HM  L R ++G  SE +  VT   + +A     + + E    R+++P+ + L
Sbjct: 182 GKALGYPAHMSLLTRTKTGAFSEKN-TVTFDMIEEAV----SNQSE---ERLLEPIINGL 233

Query: 279 VHHKRIVIKDSCVNAVCYGAKLML 302
            H ++I + +     +  G KL L
Sbjct: 234 QHLEQIEVNEDMEKRILNGQKLSL 257

ref|YP_029912.1| tRNA pseudouridine synthase B [Bacillus anthracis str. Sterne]
ref|NP_657778.1| TruB_N, TruB family pseudouridylate synthase (N terminal domain) [Bacillus anthracis str. A2012]
gb|AAT55963.1| tRNA pseudouridine synthase B [Bacillus anthracis str. Sterne]
sp|P59873|TRUB_BACAN tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(307 aa)

Score: 103 bits (258), Expect: 6.83948e-21
Length: 203, Idn/Pos/Gap = 71/101/39 (34%/49%/19%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           GV+ L KP   +SH+ V  +++ILR ++ GH+GTLDP VTG L +C+ RAT++ +   S 
Sbjct:   3 GVVLLHKPKGMTSHDCVFKLRKILREKRIGHTGTLDPDVTGVLPICVGRATKIAQFLTSE  62

Query: 133 GKEYVAVLRLHGMRPELDEAT-----------------VRRAIETLTGPLYQRPPLISAV 175
            K Y   + L G     ++A+                 V  A+ TLTG + Q PP+ SAV
Sbjct:  63 TKTYEGEVTL-GFSTTTEDASGEVVETKYVDRVITRKEVEEALATLTGTIEQMPPMFSAV 121

Query: 176 K-----------------RQLRIRTIYESKLLE----YDPKRRLVLFWVSCEAGTYIRTL 214
           K                 R +R  TI+E  LL+    ++ +     F V+C  GTY+RTL
Sbjct: 122 KVNGKKLYEYARAGQEVERPVRTITIHEFVLLDDREVFEGENISFRFRVTCSKGTYVRTL 181

Query: 215 CVHLGLLLGVGGHMQELRRVRSG 237
            V +G  LG   HM  L R  SG
Sbjct: 182 AVMIGEKLGFPSHMSHLVRTASG 204

ref|YP_207781.1| putative tRNA pseudouridine synthase B [Neisseria gonorrhoeae FA 1090]
gb|AAW89369.1| putative tRNA pseudouridine synthase B [Neisseria gonorrhoeae FA 1090]
sp|Q5F8W8|TRUB_NEIG1 tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(306 aa)

Score: 103 bits (257), Expect: 9.31317e-21
Length: 302, Idn/Pos/Gap = 86/130/53 (28%/43%/17%)

Query:  61 PLKRPIQEYIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIE 120
           P KRP+     +GV+ LDKP   SS+  +   +R+   EK GH+G LDP  TG L VC  
Sbjct:   5 PAKRPV-----NGVLLLDKPEGLSSNTALQKARRLFHAEKAGHTGVLDPLATGLLPVCFG  59

Query: 121 RATRLVKSQQSAGKEYVAVLRL--------------HGMRPELDEATVRRAIETLTGPLY 166
            A +  +    A K Y A L+L                 R ++  A  + A + LTG + 
Sbjct:  60 EAAKFAQYLLDADKAYTATLKLGEASSTGDAEGEIIAAARADISLAEFQTACQALTGNIR 119

Query: 167 QRPPLISAVK-----------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGT 209
           Q PP+ SA+K                 R+ R  T+Y   + E+D  + ++   V C  GT
Sbjct: 120 QVPPMFSALKHEGKPLYEYARKGIVIERKPRDITVYSIDIAEFDAPKAVIS--VRCSKGT 177

Query: 210 YIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRR 269
           YIRTL   +   +G   H+  LRR  +   +    +   H +     L +T +D   L  
Sbjct: 178 YIRTLSEGIAKHIGTFAHLTALRRTETAGFT----IAQSHTLEALANLNETERDGLLL-- 231

Query: 270 VIKPLESLLVHHKRIVIKDSCVNAVCYGAKLMLPGVLRYENDIECGEEVVIMTTKGEAVA 329
              P + L+ H  + V+ D  V+ +  G +       R+E D+     V + T  G  V 
Sbjct: 232 ---PCDVLVSHFPQTVLNDYAVHMLQCGQR------PRFEEDLPSDTPVRVYTENGRFVG 282

Query: 330 LA 331
           LA
Sbjct: 283 LA 284

emb|CAD64406.1| pseudouridylate synthase [Lactobacillus plantarum WCFS1]
ref|NP_785557.1| pseudouridylate synthase [Lactobacillus plantarum WCFS1]
sp|Q88VL5|TRUB_LACPL tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(307 aa)

Score: 103 bits (257), Expect: 9.87332e-21
Length: 265, Idn/Pos/Gap = 78/123/46 (29%/46%/17%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           +G++ L KP   +S + VA I+R+ +  K GHSGTLDP V G L +CI  AT++V+   +
Sbjct:   3 NGILPLYKPRGMTSFDCVAKIRRLYQTRKVGHSGTLDPNVDGVLPICIGNATKVVQFLVA  62

Query: 132 AGKEYVAVLRL--HGMRPELDEATVRR--------------AIETLTGPLYQRPPLISAV 175
           +GKEY   + L       +LD   + R              A+  +TG + Q PP+ SAV
Sbjct:  63 SGKEYQGSITLGFATTTEDLDGEEIARQAVTEPFTSDQVDAALAQMTGAITQIPPMFSAV 122

Query: 176 K--------------------RQLRIRTIYESKLLEYDP--KRRLVLFWVSCEAGTYIRT 213
           K                    R + I +  + +   YD   + + + F V+C  GTY+RT
Sbjct: 123 KVNGRRLYDYARSGETVERPERHITISSFKQRQASTYDSATQTQTIYFTVACSKGTYVRT 182

Query: 214 LCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKP 273
           L V +G +LGV   M +L R++SG  +  D  VT  ++           D      ++ P
Sbjct: 183 LAVDVGKVLGVPAVMSDLTRLKSGGFT-LDETVTFEEIA-------AHVDAGTAGALLAP 234

Query: 274 LESLLVHHKRIVIKDSCVNAVCYGA 298
           ++  L  + R+ + D     V  GA
Sbjct: 235 IDKALSQYPRVTLTDEQWQRVKNGA 259

ref|YP_085151.1| tRNA pseudouridine synthase B (tRNA-pseudouridine synthase I) [Bacillus cereus ZK]
gb|AAU16696.1| tRNA pseudouridine synthase B (tRNA-pseudouridine synthase I) [Bacillus cereus ZK]
sp|Q636L6|TRUB_BACCZ tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(307 aa)

Score: 102 bits (255), Expect: 1.6425e-20
Length: 203, Idn/Pos/Gap = 71/101/39 (34%/49%/19%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           GV+ L KP   +SH+ V  +++ILR ++ GH+GTLDP VTG L +C+ RAT++ +   S 
Sbjct:   3 GVVLLHKPKGMTSHDCVFKLRKILREKRIGHTGTLDPDVTGVLPICVGRATKIAQFLTSE  62

Query: 133 GKEYVAVLRLHGMRPELDEAT-----------------VRRAIETLTGPLYQRPPLISAV 175
            K Y   + L G     ++A+                 V  A+ TLTG + Q PP+ SAV
Sbjct:  63 TKTYEGEVTL-GFSTTTEDASGEVVETKHVDRVITRKEVEEALVTLTGTIEQMPPMFSAV 121

Query: 176 K-----------------RQLRIRTIYESKLLE----YDPKRRLVLFWVSCEAGTYIRTL 214
           K                 R +R  TI+E  LL+    ++ +     F V+C  GTY+RTL
Sbjct: 122 KVNGKKLYEYARAGQEVERPVRTITIHEFVLLDDREVFEGETISFRFRVTCSKGTYVRTL 181

Query: 215 CVHLGLLLGVGGHMQELRRVRSG 237
            V +G  LG   HM  L R  SG
Sbjct: 182 AVMIGEKLGFPSHMSHLVRTASG 204

sp|Q8FPB3|TRUB_COREF tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(297 aa)

Score: 102 bits (255), Expect: 1.69824e-20
Length: 213, Idn/Pos/Gap = 74/104/43 (34%/48%/20%)

Query:  62 LKRPIQEYIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIER 121
           +  P+Q    SG++ +DKPA  +SH+VV+ ++R     K GH+GTLDP  TG L+V IER
Sbjct:   1 MNDPVQN---SGLVVVDKPAGMTSHDVVSKLRRAFSTRKVGHAGTLDPMATGVLVVGIER  57

Query: 122 ATRLVKSQQSAGKEYVAVLRLHGMR---------------PELDEATVRRAIETLTGPLY 166
            TR +    +  K Y A +RL                     LD+  +  A+ +LTG + 
Sbjct:  58 GTRFLAHLVATTKAYDATIRLGASTTTDDREGDVVFSADASTLDDEQITTAVTSLTGEIM 117

Query: 167 QRPPLISAVK-----RQLRIR------------TIYESKLLEYDPKRRLVLF-----WVS 204
           Q+P  +SA+K        R+R            T+    +LE   +RR   F      V 
Sbjct: 118 QKPASVSAIKIDGKRAHERVRDGEVVDIPARPVTVSVFDVLE---QRREGGFVDLDVRVH 174

Query: 205 CEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSG 237
           C +GTYIR+L   LG  LGVGGH+  LRR   G
Sbjct: 175 CSSGTYIRSLARDLGAALGVGGHLTALRRTEVG 207

ref|ZP_00293532.1| COG0130: Pseudouridine synthase [Thermobifida fusca]
(293 aa)

Score: 102 bits (255), Expect: 1.75588e-20
Length: 206, Idn/Pos/Gap = 75/101/38 (36%/49%/18%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           GV+ +DKPA  +SH+VVA ++R+    + GH+GTLDP  TG L+V + +ATRL+      
Sbjct:   4 GVVIVDKPAGWTSHDVVARVRRLAGTRRVGHAGTLDPMATGVLVVGVGKATRLLGYLALT  63

Query: 133 GKEYVAVLRLHG-------------MRP--ELDEATVRRAIETLTGPLYQRPPLISAVK- 176
            K Y A +RL                RP   +DEA V      LTG ++Q PP +SAVK 
Sbjct:  64 EKVYEATIRLGQSTTTDDAEGELLERRPADHIDEAAVHAGTRALTGVIHQVPPQVSAVKV 123

Query: 177 ------RQLRIRTIYESKLLEYDPKRRLVLFW----------------VSCEAGTYIRTL 214
                 R+ R     E K  E       V  +                V+C +GTYIR+L
Sbjct: 124 RGQRAYRRARAGETVELKAREVTVHEFTVTGFRRVDSPDGAFVDVDARVTCSSGTYIRSL 183

Query: 215 CVHLGLLLGVGGHMQELRRVRSGVHS 240
              LG  LGVGGH+  LRR R G ++
Sbjct: 184 ARDLGADLGVGGHLTALRRTRVGPYT 209

ref|YP_160346.1| tRNA pseudouridine 55 synthase [Azoarcus sp. EbN1]
emb|CAI09445.1| tRNA pseudouridine 55 synthase [Azoarcus sp. EbN1]
sp|Q5NZR9|TRUB_AZOSE tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(308 aa)

Score: 102 bits (255), Expect: 1.89281e-20
Length: 201, Idn/Pos/Gap = 70/98/31 (34%/48%/15%)

Query:  67 QEYIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLV 126
           Q  I  GV+ LDKP   +S+  +   +R+L   K GH+GTLDP  TG L + +  AT+  
Sbjct:  10 QRRIVDGVLLLDKPRGLTSNAALQTARRLLNAAKAGHTGTLDPMATGLLPLTLGEATKFS  69

Query: 127 KSQQSAGKEYVAVLRLHGMRPELDEA---------------TVRRAIETLTGPLYQRPPL 171
           +    A K Y A +RL G+  +  +A               ++R+A+  LTG + Q PP+
Sbjct:  70 QMLLDADKAYEATVRL-GIETDTGDAEGAAIATAPVHVTDDSIRQALAALTGEIEQVPPM 128

Query: 172 ISAVKRQLRIRTIYESKLLEYDPKRRLVLFW---------------VSCEAGTYIRTLCV 216
            SA+KR  +    Y    +E +   R V                  V C  GTY+RTL +
Sbjct: 129 YSALKRDGKPLYEYARAGIEVERAARPVTIHSLELLGVEGDSLRIRVDCSKGTYVRTLAI 188

Query: 217 HLGLLLGVGGHMQELRRVRSG 237
            LG LLG GGH+ ELRR R G
Sbjct: 189 DLGRLLGCGGHLTELRRTRIG 209

ref|NP_228665.1| tRNA pseudouridine 55 synthase [Thermotoga maritima MSB8]
gb|AAD35938.1| tRNA pseudouridine 55 synthase [Thermotoga maritima MSB8]
sp|Q9WZW0|TRUB_THEMA tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
pdb|1R3E|A Chain A, Crystal Structure Of Trna Pseudouridine Synthase Trub And Its Rna Complex: Rna-Protein Recognition Through A Combination Of Rigid Docking And Induced Fit
(309 aa)

Score: 102 bits (254), Expect: 2.12735e-20
Length: 324, Idn/Pos/Gap = 91/147/44 (28%/45%/13%)

Query:  70 IRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQ 129
           ++ G++   KP  P+SH+VV  +++ L+  K GH GTLDP   G LI+ + + TR+++  
Sbjct:   1 MKHGILVAYKPKGPTSHDVVDEVRKKLKTRKVGHGGTLDPFACGVLIIGVNQGTRILEFY  60

Query: 130 QSAGKEYVAVLRLHGMRPELD--------------EATVRRAIETLTGPLYQRPPLISA- 174
           +   K Y   +RL  +    D              E  +R AI +  G   Q PP  SA 
Sbjct:  61 KDLKKVYWVKMRLGLITETFDITGEVVEERECNVTEEEIREAIFSFVGEYDQVPPAYSAK 120

Query: 175 -VKRQLRIRTIYESKLLEYDPKR-------------RLVLFWVSCEAGTYIRTLCVHLGL 220
             K +   +   E K++   PKR             R V F V    GTYIR+LC+ +G 
Sbjct: 121 KYKGERLYKLAREGKIINLPPKRVKIFKIWDVNIEGRDVSFRVEVSPGTYIRSLCMDIGY 180

Query: 221 LLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPLESLLVH 280
            LG G    EL R   G H       T+ + L+   +F+   +E  +   I PLE  L  
Sbjct: 181 KLGCGATAVELVRESVGPH-------TIEESLN---VFEAAPEE--IENRIIPLEKCLEW 228

Query: 281 HKRIVIKDSCVNAVCYGAKLMLPGVLRYENDIECGEEVVIMTTKGEAVALAIAHMSTSEI 340
             R+V+       +  G+++ L  +L+  +  + GE V +   +G  +ALA A  ++S +
Sbjct: 229 LPRVVVHQESTKMILNGSQIHLE-MLKEWDGFKKGEVVRVFNEEGRLLALAEAERNSSFL 287

Query: 341 ASCDHGVVARIKRVVMERDLYPRR 364
            +       R +RV+  R ++  R
Sbjct: 288 ETLRKH--ERNERVLTLRKVFNTR 309

ref|ZP_00309003.1| COG0130: Pseudouridine synthase [Cytophaga hutchinsonii]
(225 aa)

Score: 102 bits (254), Expect: 2.4928e-20
Length: 197, Idn/Pos/Gap = 64/96/30 (32%/48%/15%)

Query:  74 VINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAG 133
           V+ LDKP + +S +VV  ++R+L+++K GH+GTLDP  TG LIVC  + T+ ++S  +  
Sbjct:  12 VLCLDKPYHWTSFDVVKKVRRVLKMKKVGHAGTLDPLATGLLIVCTGKKTKTIESLMADE  71

Query: 134 KEYVAVLRLHGMRPELD---------------EATVRRAIETLTGPLYQRPPLISAVKRQ 178
           KEY   + L       D               E  +R+ ++   G + Q PP+ SAVK  
Sbjct:  72 KEYSGAIGLGATTASYDLELPLENHTDISGLTETQIRKTVKQFLGTITQIPPIHSAVKVD 131

Query: 179 ---------------LRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLLLG 223
                          ++ R ++  +      +  LV F + C  GTYIRT+    G  LG
Sbjct: 132 GKRAYDEARKGNEVIIKSRQVFIKEFKITKVELPLVYFNIVCSKGTYIRTIANDFGKALG 191

Query: 224 VGGHMQELRRVRSGVHS 240
            GGH+  LRR R G  S
Sbjct: 192 CGGHLNALRRERIGTLS 208

ref|ZP_00315709.1| COG0130: Pseudouridine synthase [Microbulbifer degradans 2-40]
(313 aa)

Score: 101 bits (252), Expect: 3.48044e-20
Length: 207, Idn/Pos/Gap = 72/102/38 (34%/49%/18%)

Query:  64 RPIQEYIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERAT 123
           RPI     SGVI +DKPA  SS+ V+  +KR+    K GH+G+LDP  TG L VC   AT
Sbjct:   9 RPI-----SGVIVIDKPAGDSSNGVLQRVKRLFFANKAGHTGSLDPLATGVLPVCFGDAT  63

Query: 124 RLVKSQQSAGKEYVAVLRLHGMR---------------PELDEATVRRAIETLTGPLYQR 168
           +  +    + KEYV+  R   +                 +L +A V +AI+   G + Q 
Sbjct:  64 KFSQFLLDSDKEYVSTFRFGEVTDTADSDGEVLESIDASKLTKADVLKAIKAYIGDIDQV 123

Query: 169 PPLISAVK-----------------RQLRIRTIYESKLLEYDPKRRL-VLFWVSCEAGTY 210
           PP+ SA+K                 R+ R  T+YE +LL + P         V C  GTY
Sbjct: 124 PPMYSALKRNGQPLYKLARQGIEVEREPRPVTVYEFELLAFRPGAVAEADVRVFCSKGTY 183

Query: 211 IRTLCVHLGLLLGVGGHMQELRRVRSG 237
           IR+L   +G  L +GGH+ +LRR ++G
Sbjct: 184 IRSLASDIGADLELGGHVAKLRRTQAG 210

ref|ZP_00383555.1| COG0130: Pseudouridine synthase [Lactococcus lactis subsp. cremoris SK11]
(330 aa)

Score: 101 bits (252), Expect: 4.18171e-20
Length: 203, Idn/Pos/Gap = 64/104/38 (31%/51%/18%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           +G++N+ K A  +S +VVA ++ IL+ +K GH GTLDP VTG L + + ++TRL++  ++
Sbjct:   6 NGILNVYKEAGWTSFDVVAKLRCILKTKKIGHGGTLDPSVTGVLPIAVGKSTRLLEYMEA  65

Query: 132 AGKEYV----------------AVLRLHGMRPELDEATVRRAIETLTGPLYQRPPLISAV 175
           AGK Y                 A++    ++  L E+ +  A+    G + Q PP+ SAV
Sbjct:  66 AGKIYEGQVTIGFSTETEDADGAIVNQTPVKNNLTESEIDSAMSRFVGKIKQIPPMYSAV 125

Query: 176 K--------------------RQLRIRTIYESKLLEYDPKRRLVLFW--VSCEAGTYIRT 213
           K                    R++ I++   +  ++++ +  LV F   V C  GTY+RT
Sbjct: 126 KINGKKLYEYARAGQTIERPAREITIKSFVRTSPIDWNKEEGLVTFSFKVECSKGTYVRT 185

Query: 214 LCVHLGLLLGVGGHMQELRRVRS 236
           L V L   LG  GHM +L+R  S
Sbjct: 186 LAVDLADSLGYAGHMSKLQRTAS 208

ref|ZP_00312104.1| COG0130: Pseudouridine synthase [Clostridium thermocellum ATCC 27405]
(297 aa)

Score: 101 bits (251), Expect: 4.2877e-20
Length: 197, Idn/Pos/Gap = 69/105/33 (35%/53%/16%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           +G++N+ KP   +S +VVA+++ IL+++K GH+GTLDP   G L VC  +AT+ ++    
Sbjct:   2 NGILNVLKPPGMTSFDVVAYLRGILKIKKIGHTGTLDPGAAGVLPVCTGKATKAIEYLSD  61

Query: 132 AGKEYVAVLRL---------HG--MRPELDEATV---RRAIETLTGPLYQRPPLISAVKR 177
             K Y A L L         +G  +R +  +A+V    + I++  G   Q PP+ SAVK 
Sbjct:  62 KDKVYRAELLLGVSTDTQDSYGEVIREQEVKASVEDIEKVIKSFEGDYSQLPPMYSAVK- 120

Query: 178 QLRIRTIYESKL----LEYDPKR-------------RLVLFWVSCEAGTYIRTLCVHLGL 220
            +  + +YE       +E  P++               V+F V C  GTYIRTLC  +G 
Sbjct: 121 -MNGKKLYELARSGIEVERTPRKVKIHFINILSIRGNRVVFDVGCSKGTYIRTLCSDVGD 179

Query: 221 LLGVGGHMQELRRVRSG 237
            LG GGHM  L R++SG
Sbjct: 180 KLGCGGHMGFLVRLKSG 196

emb|CAB87785.1| tRNA synthase-like protein [Arabidopsis thaliana]
ref|NP_196950.1| pseudouridylate synthase TruB family protein [Arabidopsis thaliana]
pir||T48619 tRNA synthase-like protein - Arabidopsis thaliana
(540 aa)

Score: 101 bits (251), Expect: 4.50782e-20
Length: 203, Idn/Pos/Gap = 66/102/32 (32%/50%/15%)

Query:  74 VINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAG 133
           V+ ++KP   +S  V   ++R+++V+K GH+GTLDP  TG LIVC+ +AT++V   Q   
Sbjct: 323 VLLVNKPKGWTSFTVCGKLRRLVKVKKVGHAGTLDPMATGLLIVCVGKATKVVDRYQGMI 382

Query: 134 KEYVAVLRLHGMRPELDEAT---------------VRRAIETLTGPLYQRPPLISAVK-- 176
           K Y  V RL      LD  +               +++A+ +  G ++Q PP+ SA+K  
Sbjct: 383 KGYSGVFRLGEATSTLDADSPVIQRESWEHIKDDDIKKALTSFLGEIWQVPPMFSAIKVG 442

Query: 177 ------RQLRIRTIYES----KLLEYDPKRRL-----VLFWVSCEAGTYIRTLCVHLGLL 221
                 +  R  T+  S     + ++D +R L     ++F V C  GTYIR+LC  L   
Sbjct: 443 GEKMYEKARRGETVELSPRRISIFQFDIERSLDDRQNLIFRVICSKGTYIRSLCADLAKA 502

Query: 222 LGVGGHMQELRRVRSGVHSEYDG 244
           LG   H+  LRR   G +S  D 
Sbjct: 503 LGSCAHLTALRRDSIGEYSANDA 525

sp|Q812X9|TRUB_BACCR tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(307 aa)

Score: 101 bits (251), Expect: 5.10883e-20
Length: 203, Idn/Pos/Gap = 69/100/39 (33%/49%/19%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           GV+ L KP   +SH+ V  +++ILR ++ GH+GTLDP VTG L +C+ RAT++ +   S 
Sbjct:   3 GVVLLHKPKGMTSHDCVFKLRKILREKRIGHTGTLDPDVTGVLPICVGRATKIAQFLTSE  62

Query: 133 GKEYVAVLRLHGMRPELDEAT-----------------VRRAIETLTGPLYQRPPLISAV 175
            K Y   + L G     ++A+                 V + +  LTG + Q PP+ SAV
Sbjct:  63 TKTYEGEVTL-GFSTTTEDASGEVVETKNVDRTITRMEVEKVLAELTGTIEQMPPMFSAV 121

Query: 176 K-----------------RQLRIRTIYESKLLE----YDPKRRLVLFWVSCEAGTYIRTL 214
           K                 R +R  TI+E  LL+    ++ +     F V+C  GTY+RTL
Sbjct: 122 KVNGKKLYEYARAGQEVERPVRTITIHEFVLLDDREVFEGENISFRFRVTCSKGTYVRTL 181

Query: 215 CVHLGLLLGVGGHMQELRRVRSG 237
            V +G  LG   HM  L R  SG
Sbjct: 182 AVMIGEKLGFPSHMSHLVRTASG 204

ref|YP_037871.1| tRNA pseudouridine synthase B [Bacillus thuringiensis serovar konkukian str. 97-27]
gb|AAT60591.1| tRNA pseudouridine synthase B [Bacillus thuringiensis serovar konkukian str. 97-27]
sp|Q6HF05|TRUB_BACHK tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(307 aa)

Score: 100 bits (250), Expect: 5.69415e-20
Length: 203, Idn/Pos/Gap = 70/100/39 (34%/49%/19%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           GV+ L KP   +SH+ V  +++ILR ++ GH+GTLDP VTG L +C+ RAT++ +   S 
Sbjct:   3 GVVLLHKPKGMTSHDCVFKLRKILREKRIGHTGTLDPDVTGVLPICVGRATKIAQFLTSE  62

Query: 133 GKEYVAVLRLHGMRPELDEAT-----------------VRRAIETLTGPLYQRPPLISAV 175
            K Y   + L G     ++A+                 V  A+  LTG + Q PP+ SAV
Sbjct:  63 TKTYEGEVTL-GFSTTTEDASGEVVETKHVDRVITRKEVEGALAALTGTIEQMPPMFSAV 121

Query: 176 K-----------------RQLRIRTIYESKLLE----YDPKRRLVLFWVSCEAGTYIRTL 214
           K                 R +R  TI+E  LL+    ++ +     F V+C  GTY+RTL
Sbjct: 122 KVNGKKLYEYARAGQEVERPVRTITIHEFVLLDDREVFEGETISFRFRVTCSKGTYVRTL 181

Query: 215 CVHLGLLLGVGGHMQELRRVRSG 237
            V +G  LG   HM  L R  SG
Sbjct: 182 AVMIGEKLGFPSHMSHLVRTASG 204

ref|ZP_00332027.1| COG0130: Pseudouridine synthase [Streptococcus suis 89/1591]
(292 aa)

Score: 100 bits (249), Expect: 7.43678e-20
Length: 201, Idn/Pos/Gap = 69/95/35 (34%/47%/17%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           SG+IN+ K A  +SH+VV  +++IL+ +K GH GTLDP VTG L + + +ATR+++  Q 
Sbjct:   3 SGIINVKKEAGMTSHDVVFKLRKILQEKKIGHGGTLDPDVTGVLPIAVGKATRMIEYMQE  62

Query: 132 AGKEYVAVLRLH-------------GMRPELD--EATVRRAIETLTGPLYQRPPLISAVK 176
            GK Y   + L                 P LD  E  V  A+ +  G + Q PP+ SAVK
Sbjct:  63 EGKIYEGEITLGFSTTTEDSSGDLVERTPVLDIAEQAVDEAMTSFVGTITQIPPMYSAVK 122

Query: 177 --------------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCV 216
                               RQ+ I +   +  +E         F V C  GTY+RTL V
Sbjct: 123 VNGRKLYEYARTGEEVERPQRQIEIYSFERTSPIELVDDCARFTFRVRCGKGTYVRTLSV 182

Query: 217 HLGLLLGVGGHMQELRRVRSG 237
            LG  LG   HM +L R  S 
Sbjct: 183 DLGAKLGYASHMSKLERTGSA 203

ref|NP_777954.1| tRNA pseudouridine synthase B [Buchnera aphidicola str. Bp (Baizongia pistaciae)]
gb|AAO27059.1| tRNA pseudouridine synthase B [Buchnera aphidicola str. Bp (Baizongia pistaciae)]
sp|Q89AF6|TRUB_BUCBP tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(302 aa)

Score: 100 bits (249), Expect: 7.4991e-20
Length: 201, Idn/Pos/Gap = 63/100/31 (31%/49%/15%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           G+I +DKP   SSHE +  +K IL+++K GH+GTLDP  TG L +C  RAT+  +   + 
Sbjct:  10 GIILIDKPYGLSSHETLQKVKGILKIKKMGHTGTLDPLATGMLPMCCGRATKFSQFLMNF  69

Query: 133 GKEYVAVLRLHG-------------MRP-ELDEATVRRAIETLTGPLYQRPPLISAVK-- 176
            K Y  + +L               +RP       +++ +++  G + Q P + SA+K  
Sbjct:  70 KKRYRVIAKLGQKTSTSDSEGQIIHVRPITFTNLQLQKVLKSFHGKIKQIPSMYSAIKYH 129

Query: 177 ---------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLL 221
                          R++R   IYE K+L Y  K + +   + C  GTYIRTL   +G  
Sbjct: 130 GHALYKYARQGIVISRKVRDAIIYELKVLGYSYKHKYLELDIICSKGTYIRTLIEDVGEK 189

Query: 222 LGVGGHMQELRRVRSGVHSEY 242
           L  G H+  LRR++ G ++ +
Sbjct: 190 LNCGAHVISLRRLQVGNYTSF 210

ref|ZP_00239776.1| tRNA pseudouridine synthase B [Bacillus cereus G9241]
gb|EAL12611.1| tRNA pseudouridine synthase B [Bacillus cereus G9241]
(307 aa)

Score: 100 bits (248), Expect: 9.63204e-20
Length: 203, Idn/Pos/Gap = 69/99/39 (33%/48%/19%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           GV+ L KP   +SH+ V  +++ILR ++ GH+GTLDP VTG L +C+ RAT++ +   S 
Sbjct:   3 GVVLLHKPKGMTSHDCVFKLRKILREKRIGHTGTLDPDVTGVLPICVGRATKIAQFLTSE  62

Query: 133 GKEYVAVLRLHGMRPELDEAT-----------------VRRAIETLTGPLYQRPPLISAV 175
            K Y   + L G     ++A+                 V   +  LTG + Q PP+ SAV
Sbjct:  63 TKTYEGEVTL-GFSTTTEDASGEVVETKHVDRVITRKEVEEVLAALTGTIEQMPPMFSAV 121

Query: 176 K-----------------RQLRIRTIYESKLLE----YDPKRRLVLFWVSCEAGTYIRTL 214
           K                 R +R  TI+E  LL+    ++ +     F V+C  GTY+RTL
Sbjct: 122 KVNGKKLYEYARAGQEVERPVRTITIHEFVLLDDREVFEGENISFRFRVTCSKGTYVRTL 181

Query: 215 CVHLGLLLGVGGHMQELRRVRSG 237
            V +G  LG   HM  L R  SG
Sbjct: 182 AVMIGEKLGFPSHMSHLVRTASG 204

ref|NP_217309.1| PROBABLE TRNA PSEUDOURIDINE SYNTHASE B TRUB (TRNA PSEUDOURIDINE 55 SYNTHASE) (PSI55 SYNTHASE) (PSEUDOURIDYLATE SYNTHASE) (URACIL HYDROLYASE) [Mycobacterium tuberculosis H37Rv]
ref|NP_856462.1| PROBABLE TRNA PSEUDOURIDINE SYNTHASE B TRUB (TRNA PSEUDOURIDINE 55 SYNTHASE) (PSI55 SYNTHASE) (PSEUDOURIDYLATE SYNTHASE) (URACIL HYDROLYASE) [Mycobacterium bovis AF2122/97]
emb|CAA15588.1| PROBABLE TRNA PSEUDOURIDINE SYNTHASE B TRUB (TRNA PSEUDOURIDINE 55 SYNTHASE) (PSI55 SYNTHASE) (PSEUDOURIDYLATE SYNTHASE) (URACIL HYDROLYASE) [Mycobacterium tuberculosis H37Rv]
emb|CAD95001.1| PROBABLE TRNA PSEUDOURIDINE SYNTHASE B TRUB (TRNA PSEUDOURIDINE 55 SYNTHASE) (PSI55 SYNTHASE) (PSEUDOURIDYLATE SYNTHASE) (URACIL HYDROLYASE) [Mycobacterium bovis AF2122/97]
gb|AAK47182.1| tRNA pseudouridine synthase B [Mycobacterium tuberculosis CDC1551]
sp|P62190|TRUB_MYCTU tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase) (MTB-TRUB)
sp|P62189|TRUB_MYCBO tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
ref|NP_337368.1| tRNA pseudouridine synthase B [Mycobacterium tuberculosis CDC1551]
(298 aa)

Score: 100 bits (248), Expect: 1.21669e-19
Length: 200, Idn/Pos/Gap = 72/99/36 (36%/49%/18%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           G++ +DKPA  +SH+VV   +RI    + GH+GTLDP  TG L++ IERAT+++    +A
Sbjct:   7 GIVVIDKPAGMTSHDVVGRCRRIFATRRVGHAGTLDPMATGVLVIGIERATKILGLLTAA  66

Query: 133 GKEYVAVLRLHGMRPELDEA----------------TVRRAIETLTGPLYQRPPLISAVK 176
            K Y A +RL G     ++A                 +  A+E L G + Q P  +SA+K
Sbjct:  67 PKSYAATIRL-GQTTSTEDAEGQVLQSVPAKHLTIEAIDAAMERLRGEIRQVPSSVSAIK 125

Query: 177 ----RQLRIRTIYESKLLEYDP-----------KRRLVLF----WVSCEAGTYIRTLCVH 217
               R  R+     S  LE  P           +RR  L      + C +GTYIR L   
Sbjct: 126 VGGRRAYRLARQGRSVQLEARPIRIDRFELLAARRRDQLIDIDVEIDCSSGTYIRALARD 185

Query: 218 LGLLLGVGGHMQELRRVRSG 237
           LG  LGVGGH+  LRR R G
Sbjct: 186 LGDALGVGGHVTALRRTRVG 205

pdb|1SGV|B Chain B, Structure Of Trna Psi55 Pseudouridine Synthase (Trub)
pdb|1SGV|A Chain A, Structure Of Trna Psi55 Pseudouridine Synthase (Trub)
(316 aa)

Score: 99 bits (247), Expect: 1.26852e-19
Length: 200, Idn/Pos/Gap = 72/99/36 (36%/49%/18%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           G++ +DKPA  +SH+VV   +RI    + GH+GTLDP  TG L++ IERAT+++    +A
Sbjct:   7 GIVVIDKPAGMTSHDVVGRCRRIFATRRVGHAGTLDPMATGVLVIGIERATKILGLLTAA  66

Query: 133 GKEYVAVLRLHGMRPELDEA----------------TVRRAIETLTGPLYQRPPLISAVK 176
            K Y A +RL G     ++A                 +  A+E L G + Q P  +SA+K
Sbjct:  67 PKSYAATIRL-GQTTSTEDAEGQVLQSVPAKHLTIEAIDAAMERLRGEIRQVPSSVSAIK 125

Query: 177 ----RQLRIRTIYESKLLEYDP-----------KRRLVLF----WVSCEAGTYIRTLCVH 217
               R  R+     S  LE  P           +RR  L      + C +GTYIR L   
Sbjct: 126 VGGRRAYRLARQGRSVQLEARPIRIDRFELLAARRRDQLIDIDVEIDCSSGTYIRALARD 185

Query: 218 LGLLLGVGGHMQELRRVRSG 237
           LG  LGVGGH+  LRR R G
Sbjct: 186 LGDALGVGGHVTALRRTRVG 205

ref|NP_980145.1| tRNA pseudouridine synthase B [Bacillus cereus ATCC 10987]
sp|Q732R2|TRUB_BACC1 tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
gb|AAS42753.1| tRNA pseudouridine synthase B [Bacillus cereus ATCC 10987]
(307 aa)

Score: 99 bits (247), Expect: 1.26852e-19
Length: 202, Idn/Pos/Gap = 70/100/37 (34%/49%/18%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           GV+ L KP   +SH+ +  +++ILR ++ GH+GTLDP VTG L +C+ RAT++ +   S 
Sbjct:   3 GVVLLHKPKGMTSHDCIFKLRKILREKRIGHTGTLDPDVTGVLPICVGRATKIAQFLTSE  62

Query: 133 GKEYVAVLRL---------HGMRPE---LDEATVRRAIE----TLTGPLYQRPPLISAVK 176
            K Y   + L          G   E   +D    R+ +E     LTG + Q PP+ SAVK
Sbjct:  63 TKTYEGEVTLGFSTTTEDASGEVVETKHVDRVITRKEVEEVLAALTGTIEQMPPMFSAVK 122

Query: 177 -----------------RQLRIRTIYESKLLE----YDPKRRLVLFWVSCEAGTYIRTLC 215
                            R +R  TI+E  LL+    ++ +     F V+C  GTY+RTL 
Sbjct: 123 VNGKKLYEYARAGQEVERPVRTITIHEFVLLDEREVFEGENISFRFRVTCSKGTYVRTLA 182

Query: 216 VHLGLLLGVGGHMQELRRVRSG 237
           V +G  LG   HM  L R  SG
Sbjct: 183 VMIGEKLGFPSHMSHLVRTASG 204

ref|NP_781908.1| tRNA pseudouridine synthase B [Clostridium tetani E88]
gb|AAO35845.1| tRNA pseudouridine synthase B [Clostridium tetani E88]
sp|Q895J5|TRUB_CLOTE tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(289 aa)

Score: 99 bits (246), Expect: 1.62933e-19
Length: 266, Idn/Pos/Gap = 84/128/53 (31%/48%/19%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           +GVIN+ KP N +S +VV  IK+I R++K GH+GTLDP  TG L +C+  +T++V    +
Sbjct:   2 NGVINVYKPQNITSFDVVRIIKKISRIKKVGHTGTLDPMATGVLPICLGGSTKIVDFIMN  61

Query: 132 AGKEYVAVLRLHGMRPELD---------------EATVRRAIETLTGPLYQRPPLISAVK 176
             KEY A L+L  +    D               E  V   I +  G + Q PP+ SA+K
Sbjct:  62 EHKEYRAKLKLGLITDTYDREGKVLKEEDASKILEEEVVNCINSFKGEIIQIPPMYSAIK 121

Query: 177 -----------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLG 219
                            R+ R   IY  ++L+ +     V F V+C  GTYIR+LC  +G
Sbjct: 122 IKGERLYNLARKGIEVEREGRKINIYNIEVLKVNLP--YVEFKVNCSKGTYIRSLCYDIG 179

Query: 220 LLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPLESLLV 279
             LG+G  M EL R ++G  S  +  + + D+           +E  ++  I P E  L 
Sbjct: 180 NKLGMGATMWELERTKTGNFS-IENSINLEDI-----------NEENIQEFIIPAEKALS 227

Query: 280 HHKRIVIKDSCVNAVCYGAKLMLPGV 305
            ++RI I +       Y ++L+  GV
Sbjct: 228 KYERIEIDE-------YFSRLLKNGV 246

ref|YP_060269.1| tRNA pseudouridine synthase B [Streptococcus pyogenes MGAS10394]
gb|AAT87086.1| tRNA pseudouridine synthase B [Streptococcus pyogenes MGAS10394]
gb|AAL97815.1| putative tRNA pseudouridine 55 synthase [Streptococcus pyogenes MGAS8232]
ref|NP_607316.1| putative tRNA pseudouridine 55 synthase [Streptococcus pyogenes MGAS8232]
gb|AAK34106.1| putative tRNA pseudouridine 55 synthase [Streptococcus pyogenes M1 GAS]
sp|P65859|TRUB_STRP8 tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
sp|P65858|TRUB_STRPY tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
sp|Q5XBX7|TRUB_STRP6 tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
ref|NP_269385.1| putative tRNA pseudouridine 55 synthase [Streptococcus pyogenes M1 GAS]
(294 aa)

Score: 99 bits (246), Expect: 1.68462e-19
Length: 276, Idn/Pos/Gap = 81/127/60 (29%/46%/21%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           +G+INL K A  +SH+ V  ++++L+ +K GH GTLDP V G L + + +ATR+++    
Sbjct:   3 NGIINLKKEAGMTSHDAVFKLRKLLQEKKIGHGGTLDPDVVGVLPIAVGKATRVIEYMTE  62

Query: 132 AGKEYVAVLRL----------------HGMRPELDEATVRRAIETLTGPLYQRPPLISAV 175
           AGK Y   + L                  +   L E  V + + T  G + Q PP+ SAV
Sbjct:  63 AGKVYEGQVTLGYSTTTEDASGEVVARSSLPAVLTEELVDQTMTTFLGKITQTPPMYSAV 122

Query: 176 KRQLRIRTIYESKLLEY--------DPKRRLVL--------------------FWVSCEA 207
           K   R       KL EY         P+R + +                    F V+C  
Sbjct: 123 KVNGR-------KLYEYARAGESVERPRREVTISLFERTSPLNFTEDGLCRFSFKVACSK 175

Query: 208 GTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYL 267
           GTY+RTL V LG  LGV  HM  L+R  S   +  +   T+ ++ D      + ++ S+L
Sbjct: 176 GTYVRTLAVDLGRALGVESHMSFLQRSASAGLT-LETAYTLGEIAD----MVSKQEMSFL 230

Query: 268 RRVIKPLESLLVHHKRIVIKDSCVNAVCYGAKLMLP 303
                P+E  +    ++VI D+ +  + +G +L LP
Sbjct: 231 L----PIEYGVADLPKMVIDDTELTEISFGRRLSLP 262

ref|YP_226221.1| TRNA PSEUDOURIDINE SYNTHASE B [Corynebacterium glutamicum ATCC 13032]
emb|CAF20320.1| TRNA PSEUDOURIDINE SYNTHASE B [Corynebacterium glutamicum ATCC 13032]
dbj|BAB99372.1| Pseudouridine synthase [Corynebacterium glutamicum ATCC 13032]
sp|Q8NP46|TRUB_CORGL tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
ref|NP_601185.1| pseudouridine synthase [Corynebacterium glutamicum ATCC 13032]
(297 aa)

Score: 98 bits (245), Expect: 2.25595e-19
Length: 201, Idn/Pos/Gap = 69/98/34 (34%/48%/16%)

Query:  71 RSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQ 130
           + G++ +DKPA  +SH+VV+ ++R     K GH+GTLDP  TG L+V IER TR +    
Sbjct:   7 KPGLVIVDKPAGMTSHDVVSKLRRAFSTRKVGHAGTLDPMATGVLVVGIERGTRFLAHMV  66

Query: 131 SAGKEYVAVLRLHGMRPE---------------LDEATVRRAIETLTGPLYQRPPLISAV 175
           ++ K Y A +RL                     LD +T+   I  LTG + Q+P  +SA+
Sbjct:  67 ASTKAYDATIRLGAATSTDDAEGEVISTTDASGLDHSTILAEIVNLTGDIMQKPTKVSAI 126

Query: 176 K-----RQLRIR------------TIYESKLLEY--DPKRRLVLFWVSCEAGTYIRTLCV 216
           K        R+R            T+    +L+Y  D +   +   V C +GTYIR L  
Sbjct: 127 KIDGKRAHERVRDGEEVDIPARPVTVSVFDVLDYHVDGEFYDLDVRVHCSSGTYIRALAR 186

Query: 217 HLGLLLGVGGHMQELRRVRSG 237
            LG  L VGGH+  LRR   G
Sbjct: 187 DLGNALQVGGHLTALRRTEVG 207

ref|NP_939819.1| tRNA pseudouridine synthase B [Corynebacterium diphtheriae NCTC 13129]
emb|CAE49999.1| tRNA pseudouridine synthase B [Corynebacterium diphtheriae]
sp|P60343|TRUB_CORDI tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(300 aa)

Score: 98 bits (245), Expect: 2.45226e-19
Length: 206, Idn/Pos/Gap = 69/98/43 (33%/47%/20%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           SG++ +DKP   +SH+VV+ I+R    +K GH+GTLDP  TG L++ +ER T+ +    +
Sbjct:   8 SGLVIVDKPQGMTSHDVVSKIRRTFSTKKVGHAGTLDPMATGVLVLGLERGTKFLAHMVA  67

Query: 132 AGKEYVAVLRLHGMRPELD------------------EATVRRAIETLTGPLYQRPPLIS 173
           + K Y A +RL       D                  E  +  A++   G + QRP  +S
Sbjct:  68 STKSYTATIRLGAATTTDDREGETITSASPDQLAGITETKISDAVKQFRGSIMQRPAAVS 127

Query: 174 AVK-----RQLRIR------------TIYESKLLEYDPKRRLVLFW-----VSCEAGTYI 211
           A+K        R+R            TI    +LE    RR   F      V C +GTYI
Sbjct: 128 AIKIDGKRAHQRVREGEKVEIPARPVTISRYDILEI---RRDAAFIDIDVEVDCSSGTYI 184

Query: 212 RTLCVHLGLLLGVGGHMQELRRVRSG 237
           R+L   LG  LGVGGH+  LRR + G
Sbjct: 185 RSLARDLGEELGVGGHLTALRRTQVG 210

gb|AAN58836.1| putative tRNA pseudouridine 5S synthase [Streptococcus mutans UA159]
ref|NP_721530.1| putative tRNA pseudouridine 5S synthase [Streptococcus mutans UA159]
sp|Q8DU15|TRUB_STRMU tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(293 aa)

Score: 98 bits (245), Expect: 2.51442e-19
Length: 268, Idn/Pos/Gap = 81/123/47 (30%/45%/17%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           SG+INL K A  +SH+ V  +++IL+ +K GH GTLDP V G L + + +ATR+++    
Sbjct:   3 SGIINLKKEAGMTSHDAVFKLRKILKEKKIGHGGTLDPDVIGVLPIAVGKATRVLEYMTE  62

Query: 132 AGKEYVAVLRLHGMRPELDEAT-----------------VRRAIETLTGPLYQRPPLISA 174
           AGK Y   + L G     ++A+                 + +A+    G + Q PP+ SA
Sbjct:  63 AGKVYEGQITL-GFSTTTEDASGELLQWTPVDETLSVELIDQAMTCFMGQITQVPPMYSA 121

Query: 175 VK--------------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTL 214
           VK                    RQ+RI     +  L ++ +     F VSC  GTYIRTL
Sbjct: 122 VKVNGKKLYEYARAGQEVERPQRQVRIYDFKRTSDLVFEDECCHFDFRVSCSKGTYIRTL 181

Query: 215 CVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPL 274
            V LG  LG   HM  L+R  S    +    +T+ ++ +        KD S+L     P+
Sbjct: 182 AVDLGQKLGYASHMSFLKRTASA-GLDLSQALTLAEIAEKV----EEKDFSFLL----PI 232

Query: 275 ESLLVHHKRIVIKDSCVNAVCYGAKLML 302
           E  ++   RI +       V +G +L L
Sbjct: 233 EYGVLDLPRIDLNPKQTKEVSFGRRLKL 260

ref|NP_802349.1| putative tRNA pseudouridine 55 synthase [Streptococcus pyogenes SSI-1]
sp|Q8K7B8|TRUB_STRP3 tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
dbj|BAC64182.1| putative tRNA pseudouridine 55 synthase [Streptococcus pyogenes SSI-1]
(294 aa)

Score: 98 bits (245), Expect: 2.68798e-19
Length: 276, Idn/Pos/Gap = 81/127/60 (29%/46%/21%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           +G+INL K A  +SH+ V  ++++L+ +K GH GTLDP V G L + + +ATR+++    
Sbjct:   3 NGIINLKKEAGMTSHDAVFKLRKLLQEKKIGHGGTLDPDVVGVLPIAVGKATRVIEYMTE  62

Query: 132 AGKEYVAVLRL----------------HGMRPELDEATVRRAIETLTGPLYQRPPLISAV 175
           AGK Y   + L                  +   L E  V + + T  G + Q PP+ SAV
Sbjct:  63 AGKVYEGQVTLGYSTTTEDASGEVVARSSLPAVLTEELVDQTMTTFLGKITQTPPMYSAV 122

Query: 176 KRQLRIRTIYESKLLEY--------DPKRRLVL--------------------FWVSCEA 207
           K   R       KL EY         P+R + +                    F V+C  
Sbjct: 123 KVNGR-------KLYEYARAGESVERPRREVTISLFERTSPLNFTEDGLCRFSFKVACGK 175

Query: 208 GTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYL 267
           GTY+RTL V LG  LGV  HM  L+R  S   +  +   T+ ++ D      + ++ S+L
Sbjct: 176 GTYVRTLAVDLGRALGVESHMSFLQRSASAGLT-LETAYTLGEIAD----MVSKQEMSFL 230

Query: 268 RRVIKPLESLLVHHKRIVIKDSCVNAVCYGAKLMLP 303
                P+E  +    ++VI D+ +  + +G +L LP
Sbjct: 231 L----PIEYGVADLPKMVIDDTELTEISFGRRLSLP 262

ref|YP_056183.1| tRNA pseudouridine synthase B [Propionibacterium acnes KPA171202]
gb|AAT83225.1| tRNA pseudouridine synthase B [Propionibacterium acnes KPA171202]
sp|Q6A7P0|TRUB_PROAC tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(295 aa)

Score: 98 bits (244), Expect: 3.33919e-19
Length: 203, Idn/Pos/Gap = 67/101/36 (33%/49%/17%)

Query:  70 IRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQ 129
           ++SGV+ +DKPA  +SH+VV  ++R++   K GH+GTLDP  +G L+V + RATRL+   
Sbjct:   4 LQSGVLVVDKPAGVTSHQVVGRVRRLMGTRKVGHAGTLDPMASGVLVVGVNRATRLLGHL  63

Query: 130 QSAGKEYVAVLRLHGM----------------RPELDEATVRRAIETLTGPLYQRPPLIS 173
               K+Y A +RL G+                   +D+  +  A+   TG + Q P  +S
Sbjct:  64 SLHDKDYTATVRL-GVGTVTDDAEGDVTVTTDASAIDDRAIHAAMVRQTGEIQQVPAAVS 122

Query: 174 AVKRQ---------------LRIRTIYESKLLEYDPKRRLVLFWV----SCEAGTYIRTL 214
           A+K                 LR R +  S+      +R   +  V    +C +GTY+R L
Sbjct: 123 AIKVNGRRAYAKVRAGEDVVLRPRAVTVSRFEAIAIRRHGQVIDVDVEATCSSGTYVRAL 182

Query: 215 CVHLGLLLGVGGHMQELRRVRSG 237
              +G  LGVGGH+  LRR R G
Sbjct: 183 ARDVGADLGVGGHLTALRRTRVG 205

ref|ZP_00387598.1| COG0130: Pseudouridine synthase [Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365]
(298 aa)

Score: 98 bits (243), Expect: 3.62976e-19
Length: 270, Idn/Pos/Gap = 75/130/48 (27%/48%/17%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           +G+I +DK A  +S +VV  ++R+L+ +K GH+GTLDP+VTG L + + +AT+L++    
Sbjct:   3 NGIIVIDKAAGMTSGDVVYKLRRLLKQKKIGHAGTLDPEVTGVLPIALGQATKLIELMHE  62

Query: 132 AGKEYVA----------------VLRLHGMRPELDEATVRRAIETLTGPLYQRPPLISAV 175
             K YV                 +L    +   + +  ++ A+E L G + Q+PP+ SAV
Sbjct:  63 RPKAYVGEGMLGLATDSYDLEGKILAERALSQPVSDQAIKAAMEKLIGEIVQQPPIYSAV 122

Query: 176 K-----------------RQLRIRTIYESKLL---EYDPK--RRLVLFWVSCEAGTYIRT 213
           +                 R  R   ++   L    ++DP+  R+   + V C  GTY+R+
Sbjct: 123 RVNGKRLYEYAREGIPVERPKRTVQVFRYDLTAPSQFDPEKGRQTFTYEVECSKGTYVRS 182

Query: 214 LCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKP 273
           L   LG  LG+   M +LRR  S  +   D  VT+ ++ D     D  +D       I+P
Sbjct: 183 LVNDLGEELGLPAVMTKLRRTASSGYKLQDA-VTLEELADN---LDHAED------YIQP 232

Query: 274 LESLLVHHKRIVIKDSCVNAVCYGAKLMLP 303
           ++S    ++++ +  +    V  GA + LP
Sbjct: 233 IDSFFADYQQVDLDAALWQQVKNGAWIKLP 262

emb|CAG37339.1| probable tRNA pseudouridine synthase B [Desulfotalea psychrophila LSv54]
ref|YP_066346.1| tRNA pseudouridine synthase B [Desulfotalea psychrophila LSv54]
sp|Q6AJY7|TRUB_DESPS tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(246 aa)

Score: 98 bits (243), Expect: 3.69084e-19
Length: 210, Idn/Pos/Gap = 68/98/36 (32%/46%/17%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIER-ATRLVKSQQ 130
           +G+  +DKP   +S  VV+ ++RIL ++K GH+GTLDP  TG L+VC  R AT+++ S  
Sbjct:   8 AGIFLIDKPVGITSFGVVSRVRRILGMKKVGHAGTLDPFATGLLVVCAGRPATKMISSFM  67

Query: 131 SAGKEYVAVLRL----HGMRPE-----------LDEATVRRAIETLTGPLYQRPPLISAV 175
              KEY+A L L        PE           L   T+   +    G   Q PP  SA+
Sbjct:  68 DGEKEYIATLCLGVETETQDPEGAEIARKQVGFLHAETIETCLAGFKGTQMQVPPAYSAL 127

Query: 176 KRQLRIRTIYESKLLEYDPKRRLV--------------------LFWVSCEAGTYIRTLC 215
           K Q +    Y  K +E     R +                    +  V C  G+YIRTL 
Sbjct: 128 KHQGKPLYYYARKGIEVKKDAREITVHEIERLGEGDLEGDHPSLVIRVRCSKGSYIRTLG 187

Query: 216 VHLGLLLGVGGHMQELRRVRSGVHSEYDGM 245
             +G +LG G H+ +LRR +SG  +  D +
Sbjct: 188 SDIGKVLGCGAHLTDLRRTKSGFFNVEDAL 217

ref|YP_061759.1| tRNA pseudouridine synthase B [Leifsonia xyli subsp. xyli str. CTCB07]
gb|AAT88654.1| tRNA pseudouridine synthase B [Leifsonia xyli subsp. xyli str. CTCB07]
sp|Q6AG41|TRUB_LEIXX tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(302 aa)

Score: 98 bits (243), Expect: 3.75295e-19
Length: 205, Idn/Pos/Gap = 71/100/37 (34%/48%/18%)

Query:  70 IRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQ 129
           I SG++ +DKP   +SH+VVA ++R+    K GH+GTLDP  TG L++ +  +TRL+   
Sbjct:   4 IGSGLLLIDKPGGWTSHDVVARVRRLAGTRKVGHAGTLDPMATGLLVLGLNSSTRLLTYI  63

Query: 130 QSAGKEYVAVLRLHGMRPELD------------------EATVRRAIETLTGPLYQRPPL 171
             A KEYV  +RL       D                  E+++   I  LTG + Q P  
Sbjct:  64 VGAEKEYVGTIRLGAATTTDDIEGEILERAEPAALAAVAESSIAEGIAALTGEIEQVPSA 123

Query: 172 ISAVKRQ-----LRIR------------TIYESKLLEYDPKRRLVLFWVS--CEAGTYIR 212
           +SAVK        R+R            T+   +LL    ++  +   V   C +GTYIR
Sbjct: 124 VSAVKVDGKRAYARVRAGEEVVLPARAVTVSAFRLLSERREQDAIDLEVRVVCSSGTYIR 183

Query: 213 TLCVHLGLLLGVGGHMQELRRVRSG 237
           +L   LG  LGVGGH+  LRR R G
Sbjct: 184 SLARDLGARLGVGGHLAALRRTRVG 208

ref|NP_961832.1| TruB [Mycobacterium avium subsp. paratuberculosis str. k10]
sp|Q73VW3|TRUB_MYCPA tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
gb|AAS05215.1| TruB [Mycobacterium avium subsp. paratuberculosis str. k10]
(293 aa)

Score: 98 bits (243), Expect: 4.1137e-19
Length: 201, Idn/Pos/Gap = 67/99/38 (33%/49%/18%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           G++ +DKPA  +SH+VV   +RI    + GH+GTLDP  TG L++ +ERAT+++    +A
Sbjct:   5 GLVVVDKPAGMTSHDVVGRCRRIFATRRVGHAGTLDPMATGVLVLGVERATKILGLLTAA  64

Query: 133 GKEYVAVLRLHGMRPELDEA----------------TVRRAIETLTGPLYQRPPLISAVK 176
            K Y A +RL G     D+A                 +  A+  L G ++Q P  +SA+K
Sbjct:  65 AKSYSATIRL-GQATSTDDAEGDVARSVDARHLTSQAIEAAVGGLRGDIHQVPSTVSAIK 123

Query: 177 --RQLRIRTIYESKLLEYDPKRRL------------------VLFWVSCEAGTYIRTLCV 216
              +   + + E + +E  P R +                  V   V C +GTY+R L  
Sbjct: 124 VAGKRAYKLVREGQAVEL-PARPVRIDRFEVRGLRAAGACVDVDVEVDCSSGTYVRALAR 182

Query: 217 HLGLLLGVGGHMQELRRVRSG 237
            LG  LGVGGH+  LRR R G
Sbjct: 183 DLGAALGVGGHLTALRRTRVG 203

ref|NP_302076.1| tRNA pseudouridine 55 synthase [Mycobacterium leprae TN]
emb|CAC30497.1| tRNA pseudouridine 55 synthase [Mycobacterium leprae]
emb|CAB36580.1| possible tRNA pseudouridine synthase B [Mycobacterium leprae]
sp|Q9Z5I4|TRUB_MYCLE tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(320 aa)

Score: 98 bits (243), Expect: 4.70122e-19
Length: 235, Idn/Pos/Gap = 80/112/43 (34%/47%/18%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           G++ +DKP+  +SH+VVA  +RI    + GH+GTLDP  TG L++ ++RAT+++     A
Sbjct:  13 GIVVIDKPSGMTSHDVVARCRRIFCTRRVGHAGTLDPMATGVLVLGVDRATKILGLLAGA  72

Query: 133 GKEYVAVLRLH----------------GMRPELDEATVRRAIETLTGPLYQRPPLISAVK 176
            KEYVA +RL                   R   DEA +  AI  L G + Q P  +SA+K
Sbjct:  73 SKEYVATIRLGQTTSTEDAEGELLQCVSARHVTDEA-IATAIGRLRGDIKQVPSAVSAIK 131

Query: 177 RQLR--IRTIYESKLLEYDPK-----RRLVL-----------------FWVSCEAGTYIR 212
              R   R + E  ++E   +     R  VL                   V C +GTYIR
Sbjct: 132 VDGRRAYRLVREGHVVELQARPVRIDRFEVLAVRPGPEVGLADVIDLDVEVECSSGTYIR 191

Query: 213 TLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYL 267
            L   LG   GVGGH+  LRR R G   E D   ++ D+ +   L   T DE+ L
Sbjct: 192 ALARDLGDAFGVGGHLTSLRRTRVG-RFELDQAWSLEDLAELPRL-SRTLDETCL 244

ref|NP_267282.1| tRNA pseudouridine synthase B [Lactococcus lactis subsp. lactis Il1403]
gb|AAK05224.1| tRNA pseudouridine synthase B (EC 4.2.1.70) [Lactococcus lactis subsp. lactis Il1403]
sp|Q9CGH0|TRUB_LACLA tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(329 aa)

Score: 97 bits (241), Expect: 6.67427e-19
Length: 203, Idn/Pos/Gap = 65/100/38 (32%/49%/18%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           +G++N+ K A  +S +VVA ++ IL+ +K GH GTLDP VTG L V + ++TRL++  ++
Sbjct:   6 NGILNVYKEAGWTSFDVVAKLRGILKTKKIGHGGTLDPSVTGVLPVAVGKSTRLLEYMEA  65

Query: 132 AGKEYVA----------------VLRLHGMRPELDEATVRRAIETLTGPLYQRPPLISAV 175
           AGK Y                  ++    +  EL E+ +   ++   G + Q PP+ SAV
Sbjct:  66 AGKIYEGEVTIGFSTETEDADGEIVSKTPVERELTESEIDSVMKNFIGKIKQIPPMYSAV 125

Query: 176 K--------------------RQLRIRTIYESKLLEYDPKRRLVLFW--VSCEAGTYIRT 213
           K                    R++ I++   +  +  D    LV F   V C  GTY+RT
Sbjct: 126 KINGKKLYEYARAGQTVDRPTREITIKSFVRTSPMMTDEAAGLVSFSFKVECSKGTYVRT 185

Query: 214 LCVHLGLLLGVGGHMQELRRVRS 236
           L V L   LG  GHM +L+R  S
Sbjct: 186 LAVDLAEQLGYAGHMSKLQRTAS 208

ref|YP_108516.1| tRNA pseudouridine synthase B [Burkholderia pseudomallei K96243]
ref|YP_102758.1| tRNA pseudouridine synthase B [Burkholderia mallei ATCC 23344]
emb|CAH35916.1| tRNA pseudouridine synthase B [Burkholderia pseudomallei K96243]
gb|AAU48843.1| tRNA pseudouridine synthase B [Burkholderia mallei ATCC 23344]
sp|Q63TQ0|TRUB_BURPS tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
sp|Q62KL1|TRUB_BURMA tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(311 aa)

Score: 97 bits (241), Expect: 7.37713e-19
Length: 260, Idn/Pos/Gap = 83/120/40 (31%/46%/15%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           GV+ LDKP   SS++ +   KR+ + +K GH+GTLDP  +G L +C   AT+  +    A
Sbjct:  17 GVLLLDKPVGLSSNDALMRAKRLYQAKKAGHTGTLDPLASGLLPLCFGEATKFSQDLLEA  76

Query: 133 GKEYVAVLRLHGMRP---------------ELDEATVRRAIETLTGPLYQRPPLISAVKR 177
            K Y A +RL G+R                  DEA VR A+    G + Q PP+ SA+KR
Sbjct:  77 DKTYEATMRL-GVRTTTGDAEGDVLDTRDVSCDEAAVRAALARFVGEIVQVPPMYSALKR 135

Query: 178 ---------------QLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLLL 222
                          +   RT+    L         V F V+C  GTY+RTL   +G  L
Sbjct: 136 DGKPLYEYARAGQTVEREGRTVTIRALALVSCALPDVTFRVTCSKGTYVRTLAEDIGEAL 195

Query: 223 GVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPLESLLVHHK 282
           G G H+  LRR   G  +  +  VT+ D LDA      T+DE   R  + P+++LL    
Sbjct: 196 GCGAHLTMLRRTGVGPLT-LEHAVTL-DALDA-----ATQDERDAR--LAPVDALLSTFP 246

Query: 283 RIVIKDSCVNAVCYGAKLML 302
            + +  +      +G +L L
Sbjct: 247 CVKLDAALATRFLHGQRLKL 266

gb|AAU44133.1| putative tRNA synthase [Oryza sativa (japonica cultivar-group)]
(488 aa)

Score: 97 bits (241), Expect: 7.50127e-19
Length: 203, Idn/Pos/Gap = 67/98/32 (33%/48%/15%)

Query:  74 VINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAG 133
           V+ +DKP   +S  V   ++R++ V+K GH+GTLDP  TG LIVC+ +AT++V   Q   
Sbjct: 271 VVLIDKPKGWTSFTVCGKLRRLVNVQKVGHAGTLDPMATGLLIVCVGKATKVVDRYQGMV 330

Query: 134 KEYVAVLRLHGMRPELD---------------EATVRRAIETLTGPLYQRPPLISAVK-- 176
           K Y  V RL       D               +  +R+   +  G ++Q PP+ SA+K  
Sbjct: 331 KGYSGVFRLGEATSTWDADSPVIQREPWEHIKDEDIRKVAASFRGEIWQVPPMFSAIKVG 390

Query: 177 ------RQLRIRTIYES----KLLEYDPKRRL-----VLFWVSCEAGTYIRTLCVHLGLL 221
                 +  R  T+  S     + ++D +R L     ++F V C  GTYIR+LC  LG  
Sbjct: 391 GEKMYDKARRGETVELSPRRISIHQFDIERSLEDRQNLIFRVICSKGTYIRSLCADLGKA 450

Query: 222 LGVGGHMQELRRVRSGVHSEYDG 244
           LG   H+  LRR   G  S  D 
Sbjct: 451 LGSCAHLTALRRDSIGDFSVNDA 473

emb|CAB37474.1| probable tRNA pseudouridine synthase [Streptomyces coelicolor A3(2)]
sp|Q9Z528|TRUB_STRCO tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
ref|NP_629836.1| probable tRNA pseudouridine synthase [Streptomyces coelicolor A3(2)]
(301 aa)

Score: 96 bits (239), Expect: 1.11031e-18
Length: 216, Idn/Pos/Gap = 69/106/42 (31%/49%/19%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           G++ +DKP+  +SH+VVA ++ I R  + GH+GTLDP  TG L++ +ERAT+L+      
Sbjct:  10 GLVIVDKPSGFTSHDVVAKMRGIARTRRVGHAGTLDPMATGVLVLGVERATKLLGHLALT  69

Query: 133 GKEYVAVLRLHGMRPELDEA----------------TVRRAIETLTGPLYQRPPLISAVK 176
            KEY+  +RL G     D+A                 +   +  L+G + Q P  +SA+K
Sbjct:  70 EKEYLGTIRL-GQTTLTDDAEGEITGSRDASKVTWEAIDAGVAELSGDIMQVPSKVSAIK 128

Query: 177 ---------------RQLRIRTIYESKLLEYDPKRRL---------VLFWVSCEAGTYIR 212
                           ++  R +  S    YD +  +         ++  V+C +GTYIR
Sbjct: 129 IKGVRSYKRAREGEEFEIPARPVTVSSFAVYDVRDAVADDGTPVLDLVVSVTCSSGTYIR 188

Query: 213 TLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTM 248
            L   LG  LGVGGH+  LRR R G + + DG  T+
Sbjct: 189 ALARDLGAGLGVGGHLTALRRTRVGPY-KLDGARTL 223

ref|ZP_00273851.1| COG0130: Pseudouridine synthase [Ralstonia metallidurans CH34]
(314 aa)

Score: 96 bits (238), Expect: 1.37931e-18
Length: 214, Idn/Pos/Gap = 76/99/33 (35%/46%/15%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           GV+ LDKP   SS++ +   KR+LR  K GH+GTLDP  TG L +C   AT+  +    A
Sbjct:  19 GVLLLDKPLGLSSNDALVRAKRLLRANKAGHTGTLDPLATGLLPLCFGEATKFSQDLLDA  78

Query: 133 GKEYVAVLRLHGMRPELD---EATVRR-----------AIETLTGPLYQRPPLISAVK-- 176
            K Y A +RL       D   E  V R           A+   TG + Q PP+ SA+K  
Sbjct:  79 DKTYEAKVRLGATTTTGDAEGEIVVERLVTCDHDALDAAVARFTGEIEQVPPMYSALKKD 138

Query: 177 ---------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLL 221
                          R  R  TI+   LL+ D    +    V+C  GTYIRTL   +G  
Sbjct: 139 GKPLYEYARAGQTVERAARQVTIHAITLLDVDLPAAMFTMRVTCSKGTYIRTLAEDVGEA 198

Query: 222 LGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQ 255
           LG G H+  LRR   G     +G VT+  + DAQ
Sbjct: 199 LGCGAHLIGLRRTAVG-DLTLEGAVTLEQI-DAQ 230

ref|ZP_00211449.1| COG0130: Pseudouridine synthase [Burkholderia cepacia R18194]
(300 aa)

Score: 96 bits (238), Expect: 1.51189e-18
Length: 264, Idn/Pos/Gap = 80/124/42 (30%/46%/15%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           GV+ LDKP   SS++ +   KR+L  +K GH+GTLDP  +G L +C   AT+  +    A
Sbjct:   8 GVLLLDKPVGLSSNDALIRAKRLLLAKKAGHTGTLDPLASGLLPLCFGEATKFSQDLLEA  67

Query: 133 GKEYVAVLRLH-------------GMRP-ELDEATVRRAIETLTGPLYQRPPLISAVKRQ 178
            K Y A +RL                RP E D A V  A+   TG + Q PP+ SA+KR 
Sbjct:  68 DKTYEATMRLGQRTATGDAEGEVIDTRPVECDRAAVEAALVRFTGEIVQVPPMYSALKRD 127

Query: 179 LRIRTIYE----SKLLEYDPKRRL-------------VLFWVSCEAGTYIRTLCVHLGLL 221
              + +YE     + +E + +                V F V+C  GTY+RTL   +G  
Sbjct: 128 G--KPLYEYARAGQTVEREGRNVTILALALLACDLPDVTFRVTCSKGTYVRTLAEDIGEA 185

Query: 222 LGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPLESLLVHH 281
           LG G H+  LRR   G  +  +  VT+  + DA    D ++D       ++P+++LL   
Sbjct: 186 LGCGAHLTMLRRTGVGALT-LEHAVTLDALSDAD---DASRDAW-----LQPVDALLSTF 236

Query: 282 KRIVIKDSCVNAVCYGAKLMLPGV 305
             + + ++      +G +L L  +
Sbjct: 237 PLVRLDETSAKRFLHGQRLPLSAL 260

gb|AAK73131.1| putative tRNA synthase [Oryza sativa]
(525 aa)

Score: 95 bits (237), Expect: 1.84709e-18
Length: 203, Idn/Pos/Gap = 67/98/32 (33%/48%/15%)

Query:  74 VINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAG 133
           V+ +DKP   +S  V   ++R++ V+K GH+GTLDP  TG LIVC+ +AT++V   Q   
Sbjct: 308 VVLIDKPKGWTSFTVCGKLRRLVNVQKVGHAGTLDPMATGLLIVCVGKATKVVDRYQGMV 367

Query: 134 KEYVAVLRLHGMRPELD---------------EATVRRAIETLTGPLYQRPPLISAVK-- 176
           K Y  V RL       D               +  +R+   +  G ++Q PP+ SA+K  
Sbjct: 368 KGYSGVFRLGEATSTWDADSPVIQREPWEHIKDEDIRKVAASFRGEIWQVPPMFSAIKVG 427

Query: 177 ------RQLRIRTIYES----KLLEYDPKRRL-----VLFWVSCEAGTYIRTLCVHLGLL 221
                 +  R  T+  S     + ++D +R L     ++F V C  GTYIR+LC  LG  
Sbjct: 428 GEKMYDKARRGETVELSPRRISIHQFDIERSLEDRQNLIFRVICSKGTYIRSLCADLGKA 487

Query: 222 LGVGGHMQELRRVRSGVHSEYDG 244
           LG   H+  LRR   G  S  D 
Sbjct: 488 LGSCAHLTALRRDSIGDFSVNDA 510

ref|YP_175721.1| tRNA pseudouridine synthase B [Bacillus clausii KSM-K16]
dbj|BAD64760.1| tRNA pseudouridine synthase B [Bacillus clausii KSM-K16]
sp|Q5WFU5|TRUB_BACSK tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(302 aa)

Score: 95 bits (237), Expect: 1.89391e-18
Length: 249, Idn/Pos/Gap = 73/112/45 (29%/44%/18%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           +G++ LDKP   +SH+ V  +++  +  K GH+GTLDP+V G L +CI +AT++VK    
Sbjct:   4 TGIVVLDKPKGWTSHDCVHQMRKWFQTRKVGHTGTLDPEVDGVLPICIGKATKVVKYMSD  63

Query: 132 AGKEYVAVLRL---------HGMRPE---LDEATVRRAIETL----TGPLYQRPPLISAV 175
             K Y+  +           HG   E   +++   R  IE L     G + Q PP  SAV
Sbjct:  64 YDKTYIGEVTFGVATTTEDAHGEVVEEKRVNKPFTRTEIEALLQAFIGKIEQTPPYYSAV 123

Query: 176 K--------------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLC 215
           K                    R + I+ +  +++    P      F V+C  GTYIRTL 
Sbjct: 124 KVNGKRLYEYARAGIEVERPTRTVEIKALTLTEITTAKPGCFSFAFSVTCTKGTYIRTLA 183

Query: 216 VHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPLE 275
           V +G   G   HM +L R  SG         T  D +      + + DE   +  ++PL+
Sbjct: 184 VDIGKKAGYPAHMSKLTRTASGP-------FTQADAIPLSAFAEMSLDERLNK--LRPLD 234

Query: 276 SLLVHHKRI 284
           + L H  R+
Sbjct: 235 TALQHFPRV 243

sp|Q9KA80|TRUB_BACHD tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
dbj|BAB06129.1| tRNA pseudouridine 5S synthase [Bacillus halodurans C-125]
ref|NP_243276.1| tRNA pseudouridine 5S synthase [Bacillus halodurans C-125]
(304 aa)

Score: 95 bits (237), Expect: 1.92578e-18
Length: 205, Idn/Pos/Gap = 65/96/36 (31%/46%/17%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           +G++ L KP   +SH+ VA ++R+L+ +K GH+GTLDP V G L VCI  AT++ +    
Sbjct:   4 TGILPLAKPRGMTSHDCVAKLRRLLKTKKVGHTGTLDPDVYGVLPVCIGHATKVAQYMSD  63

Query: 132 AGKEYVA----------------VLRLHGMRPELDEATVRRAIETLTGPLYQRPPLISAV 175
             K Y                   +    ++    EA V + + T  G + Q PP+ SAV
Sbjct:  64 YPKAYEGEVTVGFSTTTEDRSGDTVETKTIQQPFVEAVVDQVLATFVGEIKQIPPMYSAV 123

Query: 176 K-RQLRIRTIYESKLLEYDPKRRLVLFW-------------------VSCEAGTYIRTLC 215
           K R  R+     + +    P+R + +F                    VSC  GTY+RTL 
Sbjct: 124 KVRGKRLYEYARAGITVERPERTVTIFSLERMSDIVYEEGVCRFRFNVSCSKGTYVRTLA 183

Query: 216 VHLGLLLGVGGHMQELRRVRSGVHS 240
           V +G  LG   HM +L R +SG  S
Sbjct: 184 VDIGKALGYPAHMSDLVRTKSGPFS 208

ref|NP_952642.1| tRNA pseudouridine synthase B [Geobacter sulfurreducens PCA]
gb|AAR34965.1| tRNA pseudouridine synthase B [Geobacter sulfurreducens PCA]
sp|P60344|TRUB_GEOSL tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(304 aa)

Score: 95 bits (237), Expect: 2.1109e-18
Length: 195, Idn/Pos/Gap = 69/93/30 (35%/47%/15%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           G I +DKP   +SH+VVA +++ LR +K GH+GTLDP  TG L V +   T+ +     +
Sbjct:   3 GFIVIDKPIGLTSHDVVARVRQTLRQKKAGHTGTLDPFATGVLPVAVGEGTKAIPYLDES  62

Query: 133 GKEYVAVLRL---------------HGMRPELDEATVRRAIETLTGPLYQRPPLISAVKR 177
            K Y A L L                G    L+  +VR  + + TG L Q PP+ SA+KR
Sbjct:  63 TKVYRATLILGAATDTQDHTGQVVHAGDWRHLEPQSVRDVVSSFTGKLSQLPPMFSALKR 122

Query: 178 Q---------------LRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLLL 222
                              R I    L+       LV F +SC  GTY+RTL   +G  L
Sbjct: 123 DGVPLYKLARTGREVERERREIEVFSLVVDSIDLPLVTFTLSCSRGTYVRTLAHDMGERL 182

Query: 223 GVGGHMQELRRVRSG 237
           G G H+ ELRR+ SG
Sbjct: 183 GCGAHLTELRRLSSG 197

emb|CAE07059.1| putative tRNA pseudouridine 55 synthase [Synechococcus sp. WH 8102]
sp|P59884|TRUB_SYNPX tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
ref|NP_896639.1| putative tRNA pseudouridine 55 synthase [Synechococcus sp. WH 8102]
(291 aa)

Score: 95 bits (236), Expect: 3.02192e-18
Length: 196, Idn/Pos/Gap = 66/97/33 (33%/49%/16%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           G + +DKPA  +SH  V+ ++R   +++ GH GTLDP VTG L + +  ATRL+      
Sbjct:   6 GFVVIDKPAGHTSHSCVSRLRRCYGLKRVGHGGTLDPAVTGVLPIALGPATRLL-PYLPG  64

Query: 133 GKEYVAVLRLHGMR---------------PELDEATVRRAIETLTGPLYQRPPLISAV-- 175
            K Y  V++L  +                P+L    +  A+    GP+ QRPP +SAV  
Sbjct:  65 DKTYRGVIQLGSITSSDDLEGELLRQAPWPDLQPEELEVALAPFRGPIQQRPPQVSAVHV 124

Query: 176 ---KRQLRIR------------TIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGL 220
              +   R R            TI+  +LL +DP +  +   V C AGTYIR+L   LG 
Sbjct: 125 DGERAHARARRGEQMVLPPRPVTIHRLQLLHWDPNQGQLTLEVHCSAGTYIRSLARDLGE 184

Query: 221 LLGVGGHMQELRRVRS 236
            LG GG + +LRR ++
Sbjct: 185 QLGCGGCLAQLRRTQA 200

ref|NP_348430.1| Pseudouridine synthase [Clostridium acetobutylicum ATCC 824]
gb|AAK79770.1| Pseudouridine synthase [Clostridium acetobutylicum ATCC 824]
sp|Q97I48|TRUB_CLOAB tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(289 aa)

Score: 95 bits (235), Expect: 3.23052e-18
Length: 193, Idn/Pos/Gap = 65/91/33 (33%/47%/17%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           G++N+ KP   +S +VV  +K+I + +K GH+GTLDP  +G L +CI +AT++V      
Sbjct:   3 GILNIFKPIGLTSFDVVRQVKKISKEKKVGHTGTLDPLASGVLPICIGKATKIVDFVMEG  62

Query: 133 GKEYVAVLRLHGMRPELD--------------EATVRRAIETLTGPLYQRPPLISAVK-- 176
            K Y A ++L  +    D              E  +  AI +  G + Q PP+ SA+K  
Sbjct:  63 KKIYDAEMKLGEISDTYDREGKILKVNQVTSSENNIVEAIMSFQGEILQVPPMYSALKVN 122

Query: 177 ---------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLL 221
                          R  R   IY  K+L  D     V F V C  GTYIR+LC  +G  
Sbjct: 123 GIKLYDLARQGIEIERASRKIHIYAIKILSIDIP--FVKFRVECSKGTYIRSLCYDIGNK 180

Query: 222 LGVGGHMQELRRV 234
           LG G  M  L RV
Sbjct: 181 LGCGALMYNLTRV 193

ref|YP_040658.1| putative tRNA pseudouridine synthase B [Staphylococcus aureus subsp. aureus MRSA252]
emb|CAG40249.1| putative tRNA pseudouridine synthase B [Staphylococcus aureus subsp. aureus MRSA252]
sp|Q6GHG4|TRUB_STAAR tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(305 aa)

Score: 94 bits (234), Expect: 4.32614e-18
Length: 255, Idn/Pos/Gap = 77/117/45 (30%/45%/17%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           +G++ + K    +SH+VV  +++IL+ +K GH+GTLDP+V G L VCI  ATR+      
Sbjct:   3 NGILPVYKERGLTSHDVVFKLRKILKTKKIGHTGTLDPEVAGVLPVCIGNATRVSDYVMD  62

Query: 132 AGKEYVA----------------VLRLHGMR-PELDEATVRRAIETLTGPLYQRPPLISA 174
            GK Y A                 L + G+     +   + R +E+  G + Q PP+ S+
Sbjct:  63 MGKAYEATVSIGRSTTTEDQTGDTLEMKGVHSANFNNDDIDRLLESFKGIIEQIPPMYSS 122

Query: 175 V--------------------KRQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTL 214
           V                    KR++ I+ I     L++          V C  GTYIRTL
Sbjct: 123 VKVNGKKLYEYARNNETVERPKRKVNIKDIGRISELDFKENECHFKIRVICGKGTYIRTL 182

Query: 215 CVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPL 274
              +G+ LG   HM +L R+ SG      G V + D L  + + +  + +S L+  + PL
Sbjct: 183 ATDIGVKLGFPAHMSKLTRIESG------GFV-LKDSLTLEQIKELHEQDS-LQNKLFPL 234

Query: 275 ESLLVHHKRIVIKDS 289
           E  L     I IKDS
Sbjct: 235 EYGLKGLPSIKIKDS 249

dbj|BAC70259.1| putative tRNA pseudouridine synthase [Streptomyces avermitilis MA-4680]
sp|Q82K56|TRUB_STRAW tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
ref|NP_823724.1| putative tRNA pseudouridine synthase [Streptomyces avermitilis MA-4680]
(301 aa)

Score: 94 bits (234), Expect: 5.06932e-18
Length: 205, Idn/Pos/Gap = 68/101/41 (33%/49%/20%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           G++ +DKP+  +SH+VVA ++ I R  + GH+GTLDP  TG L++ +E+AT+L+      
Sbjct:  10 GLVIVDKPSGFTSHDVVAKMRGIARTRRVGHAGTLDPMATGVLVLGVEKATKLLGHLALT  69

Query: 133 GKEYVAVLRLHGMRPELDEA------------TVRRAIET----LTGPLYQRPPLISAVK 176
            KEY+  +RL G     D+A              R AI+     L+G + Q P  +SA+K
Sbjct:  70 EKEYLGTIRL-GQNTLTDDAEGEIISSTDASRVTRDAIDAGVAKLSGAIMQVPSKVSAIK 128

Query: 177 ---------------RQLRIRTIYESKLLEYDPKRRL---------VLFWVSCEAGTYIR 212
                           ++  R +  S    YD +  +         ++  V C +GTYIR
Sbjct: 129 IDGVRSYKRAREGEDFEIPARPVTVSSFAVYDVRDAVAEDGTPVLDLVVSVVCSSGTYIR 188

Query: 213 TLCVHLGLLLGVGGHMQELRRVRSG 237
            L   LG  LGVGGH+  LRR R G
Sbjct: 189 ALARDLGADLGVGGHLTALRRTRVG 213

sp|Q8NWZ0|TRUB_STAAW tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
dbj|BAB95019.1| tRNA pseudouridine 5S synthase [Staphylococcus aureus subsp. aureus MW2]
ref|NP_645971.1| tRNA pseudouridine 5S synthase [Staphylococcus aureus subsp. aureus MW2]
(305 aa)

Score: 94 bits (233), Expect: 5.74519e-18
Length: 255, Idn/Pos/Gap = 77/118/45 (30%/46%/17%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           +G++ + K    +SH+VV  +++IL+ +K GH+GTLDP+V G L VCI  ATR+      
Sbjct:   3 NGILPVYKERGLTSHDVVFKLRKILKTKKIGHTGTLDPEVAGVLPVCIGNATRVSDYVMD  62

Query: 132 AGKEYVA----------------VLRLHGMR-PELDEATVRRAIETLTGPLYQRPPLISA 174
            GK Y A                 L   G+   + ++  + R +E+  G + Q PP+ S+
Sbjct:  63 MGKAYEATVSIGRSTTTEDQTGDTLETKGVHSADFNKDDIDRLLESFKGIIEQIPPMYSS 122

Query: 175 V--------------------KRQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTL 214
           V                    KR++ I+ I     L++          V C  GTYIRTL
Sbjct: 123 VKVNGKKLYEYARNNETVERPKRKVNIKDIGRISELDFKENECHFKIRVICGKGTYIRTL 182

Query: 215 CVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPL 274
              +G+ LG   HM +L R+ SG      G V + D L  + + +  + +S L+  + PL
Sbjct: 183 ATDIGVKLGFPAHMSKLTRIESG------GFV-LKDSLTLEQIKELHEQDS-LQNKLFPL 234

Query: 275 ESLLVHHKRIVIKDS 289
           E  L     I IKDS
Sbjct: 235 EYGLKGLPSIKIKDS 249

ref|ZP_00284253.1| COG0130: Pseudouridine synthase [Burkholderia fungorum LB400]
(303 aa)

Score: 94 bits (233), Expect: 5.74519e-18
Length: 262, Idn/Pos/Gap = 77/122/44 (29%/46%/16%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           GV+ LDKP   SS++ +   KR+   +K GH+GTLDP  TG L +C   AT+  +    A
Sbjct:   8 GVLLLDKPLGLSSNDALIRAKRLYLAKKAGHTGTLDPLATGLLPLCFGEATKFSQDLLEA  67

Query: 133 GKEYVAVLRLHGMRPEL---------------DEATVRRAIETLTGPLYQRPPLISAVKR 177
            K Y A +RL G+R                  DEA +   +    G + Q PP+ SA+KR
Sbjct:  68 DKTYEATMRL-GIRTTTGDAEGEAIDTREVTCDEAAIHAVLPAFIGEITQVPPMYSALKR 126

Query: 178 QLRIRTIYE----SKLLEYDPKRRLVL-------------FWVSCEAGTYIRTLCVHLGL 220
               + +YE     + +E + ++  +L             F V+C  GTY+RTL   +G 
Sbjct: 127 DG--KPLYEYARAGQTVEREGRQVTILKLEILACALPDVTFRVTCSKGTYVRTLAEDIGE 184

Query: 221 LLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPLESLLVH 280
            LG G H+  LR  R+GV     G +T+ + +    L D  + E      ++P+++LL  
Sbjct: 185 ALGCGAHLVALR--RTGV-----GALTLENSVTLDALSDAAESER--DAWLQPVDALLST 235

Query: 281 HKRIVIKDSCVNAVCYGAKLML 302
              + + +       +G +L L
Sbjct: 236 FPLVQLNEDATRRFLHGQRLKL 257

ref|YP_186147.1| tRNA pseudouridine 55 synthase [Staphylococcus aureus subsp. aureus COL]
sp|Q5HGG0|TRUB_STAAC tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
gb|AAW38121.1| tRNA pseudouridine 55 synthase [Staphylococcus aureus subsp. aureus COL]
(305 aa)

Score: 94 bits (233), Expect: 5.79332e-18
Length: 255, Idn/Pos/Gap = 77/118/45 (30%/46%/17%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           +G++ + K    +SH+VV  +++IL+ +K GH+GTLDP+V G L VCI  ATR+      
Sbjct:   3 NGILPVYKERGLTSHDVVFKLRKILKTKKIGHTGTLDPEVAGVLPVCIGNATRVSDYVMD  62

Query: 132 AGKEYVA----------------VLRLHGMR-PELDEATVRRAIETLTGPLYQRPPLISA 174
            GK Y A                 L   G+   + ++  + R +E+  G + Q PP+ S+
Sbjct:  63 MGKAYEATVSIGRSTTTEDQTGDTLETKGVHSADFNKDDIDRLLESFKGIIEQIPPMYSS 122

Query: 175 V--------------------KRQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTL 214
           V                    KR++ I+ I     L++          V C  GTYIRTL
Sbjct: 123 VKVNGKKLYEYARNNETVERPKRKVNIKDIGRISELDFKENECHFKIRVICGKGTYIRTL 182

Query: 215 CVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPL 274
              +G+ LG   HM +L R+ SG      G V + D L  + + +  + +S L+  + PL
Sbjct: 183 ATDIGVKLGFPAHMSKLTRIESG------GFV-LKDSLTLEQIKELHEQDS-LQNKLFPL 234

Query: 275 ESLLVHHKRIVIKDS 289
           E  L     I IKDS
Sbjct: 235 EYGLKGLPSIKIKDS 249

ref|ZP_00363769.1| COG0130: Pseudouridine synthase [Polaromonas sp. JS666]
(322 aa)

Score: 94 bits (233), Expect: 5.89081e-18
Length: 203, Idn/Pos/Gap = 72/97/42 (35%/47%/20%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           GV+ LDKP   SS++ +   K +LR +K GH+GTLDP  TG L +C   AT+  + Q  A
Sbjct:   3 GVLLLDKPLGLSSNQALQKAKWLLRADKAGHTGTLDPLATGVLPLCFGAATKFSQIQLDA  62

Query: 133 GKEYVAVLRLH-------------------GMRPELDEATVRRAIETLTGPLYQRPPLIS 173
            K Y AVL L                     + PEL     RR     TGPL Q PP+ S
Sbjct:  63 DKTYEAVLLLGRKTTTADAEGDVIETRPVPEITPELLATLTRR----FTGPLAQIPPMYS 118

Query: 174 AVK-----------------RQLRIRTIYESKL-LEYDPKRRLVL-FWVSCEAGTYIRTL 214
           A+K                 R+ R  TIY+  + L +D +    +   V+C  GTYIRTL
Sbjct: 119 ALKKDGKALYEYARKGEDVEREARHITIYKLDMALTHDERAPAAIKITVTCSKGTYIRTL 178

Query: 215 CVHLGLLLGVGGHMQELRRVRSG 237
              +G  +G G H+  LRR+ +G
Sbjct: 179 GEDIGEAIGCGAHLGSLRRLETG 201

ref|ZP_00132678.1| COG0130: Pseudouridine synthase [Haemophilus somnus 2336]
ref|ZP_00122306.1| COG0130: Pseudouridine synthase [Haemophilus somnus 129PT]
(308 aa)

Score: 94 bits (233), Expect: 6.73214e-18
Length: 261, Idn/Pos/Gap = 73/122/40 (27%/46%/15%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           +G+  LDK    SS++++  +KR+ +  K GH+G LDP  TG L +C+  AT+  +    
Sbjct:  12 NGIFLLDKSQGMSSNDIMQKVKRLFQANKAGHTGALDPLATGMLPICLGEATKFSQYLLD  71

Query: 132 AGKEYVAVLRLHGMRPE---------------LDEATVRRAIETLTGPLYQRPPLISAVK 176
           A K Y  + +L G R +               +D A +  A+E   G + Q P + SA+K
Sbjct:  72 ADKRYQVIAKL-GERTDTSDADGQVVQKREVNIDLAKILTALEQFRGEIMQVPTMFSALK 130

Query: 177 -----------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLG 219
                            R+ R  +I+E K ++Y  +   +   V C  GTYIRTL   LG
Sbjct: 131 YQGKALYEYARAGITIEREARPISIFELKFIDY--QIPYLTLEVHCSKGTYIRTLVDDLG 188

Query: 220 LLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPLESLLV 279
            +LG G H+  LRR+    +  Y+ M+T+  +      F   +D   L + + P+ES ++
Sbjct: 189 EVLGCGAHVTRLRRIAVADYP-YNKMMTLEQLQQ----FSEQEDLDLLDQHLLPMESAVI 243

Query: 280 HHKRIVIKDSCVNAVCYGAKL 300
               + +      AV +G ++
Sbjct: 244 RLPGLHLTKEQARAVGFGQRI 264

dbj|BAB57433.1| tRNA pseudouridine 5S synthase [Staphylococcus aureus subsp. aureus Mu50]
sp|P65855|TRUB_STAAN tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
sp|P65854|TRUB_STAAM tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
ref|NP_374387.1| tRNA pseudouridine 5S synthase [Staphylococcus aureus subsp. aureus N315]
dbj|BAB42366.1| tRNA pseudouridine 5S synthase [Staphylococcus aureus subsp. aureus N315]
ref|NP_371795.1| tRNA pseudouridine 5S synthase [Staphylococcus aureus subsp. aureus Mu50]
(305 aa)

Score: 93 bits (232), Expect: 7.19685e-18
Length: 255, Idn/Pos/Gap = 77/117/45 (30%/45%/17%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           +G++ + K    +SH+VV  +++IL+ +K GH+GTLDP+V G L VCI  ATR+      
Sbjct:   3 NGILPVYKERGLTSHDVVFKLRKILKTKKIGHTGTLDPEVAGVLPVCIGNATRVSDYVMD  62

Query: 132 AGKEYVA----------------VLRLHGMR-PELDEATVRRAIETLTGPLYQRPPLISA 174
            GK Y A                 L   G+   + ++  + R +E   G + Q PP+ S+
Sbjct:  63 MGKAYEATVSIGRSTTTEDQTGDTLETKGVHSADFNKDDIDRLLENFKGVIEQIPPMYSS 122

Query: 175 V--------------------KRQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTL 214
           V                    KR++ I+ I     L++          V C  GTYIRTL
Sbjct: 123 VKVNGKKLYEYARNNETVERPKRKVNIKDIGRISELDFKENECHFKIRVICGKGTYIRTL 182

Query: 215 CVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPL 274
              +G+ LG   HM +L R+ SG      G V + D L  + + +  + +S L+  + PL
Sbjct: 183 ATDIGVKLGFPAHMSKLTRIESG------GFV-LKDSLTLEQIKELHEQDS-LQNKLFPL 234

Query: 275 ESLLVHHKRIVIKDS 289
           E  L     I IKDS
Sbjct: 235 EYGLKGLPSIKIKDS 249

emb|CAG42982.1| putative tRNA pseudouridine synthase B [Staphylococcus aureus subsp. aureus MSSA476]
sp|Q6G9U2|TRUB_STAAS tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
ref|YP_043331.1| putative tRNA pseudouridine synthase B [Staphylococcus aureus subsp. aureus MSSA476]
(305 aa)

Score: 93 bits (232), Expect: 8.5751e-18
Length: 255, Idn/Pos/Gap = 76/119/45 (29%/46%/17%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           +G++ + K    +SH+VV  +++IL+ +K GH+GTLDP+V G L VCI  ATR+      
Sbjct:   3 NGILPVYKERGLTSHDVVFKLRKILKTKKIGHTGTLDPEVAGVLPVCIGNATRVSDYVMD  62

Query: 132 AGKEYVAVLRL----------------HGMR-PELDEATVRRAIETLTGPLYQRPPLISA 174
            GK Y A + +                 G+   + ++  + R +E+  G + Q PP+ S+
Sbjct:  63 MGKAYEATVSIGRSTTTEDQTGDTLEKKGVHSADFNKDDIDRLLESFKGIIEQIPPMYSS 122

Query: 175 V--------------------KRQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTL 214
           V                    KR++ I+ I     L++          V C  GTYIRTL
Sbjct: 123 VKVNGKKLYEYARNNETVERPKRKVNIKDIGRISELDFKENECHFKIRVICGKGTYIRTL 182

Query: 215 CVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPL 274
              +G+ LG   HM +L R+ SG      G V + D L  + + +  + +S L+  + PL
Sbjct: 183 ATDIGVKLGFPAHMSKLTRIESG------GFV-LKDSLTLEQIKELHEQDS-LQNKLFPL 234

Query: 275 ESLLVHHKRIVIKDS 289
           E  L     I IKDS
Sbjct: 235 EYGLKGLPSIKIKDS 249

gb|AAV97051.1| tRNA pseudouridine synthase B [Silicibacter pomeroyi DSS-3]
ref|YP_169025.1| tRNA pseudouridine synthase B [Silicibacter pomeroyi DSS-3]
sp|Q5LLT4|TRUB_SILPO tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(303 aa)

Score: 93 bits (232), Expect: 8.64694e-18
Length: 292, Idn/Pos/Gap = 92/134/46 (31%/45%/15%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           SG + +DKPA  +S  VV  ++  L   K GH+GTLDP+ TG L + +  AT+ V     
Sbjct:  11 SGWLVVDKPAGMTSTAVVNKVRWALGANKAGHAGTLDPEATGVLAIALGEATKTVPYITD  70

Query: 132 AGKEYVAVLRLHGMRPELDEA---------------TVRRAIETLTGPLYQRPPLISAVK 176
           A K YV  +RL G     D+A                ++ A+    G + Q PP  SAVK
Sbjct:  71 ALKAYVFTVRL-GQATNTDDAEGEVIASSDLRPTDEQIKDALAPFLGDIMQVPPKFSAVK 129

Query: 177 ---------------RQLRIRTIYESKLLEYD-PKRRLVLFWVSCEAGTYIRTLCVHLGL 220
                           +L  R ++  +LL  D P    VL  ++C  G Y+R++   LG 
Sbjct: 130 IDGQRAYKLARDGEDVELAARPLWVEELLMLDRPDPDHVLLEMTCGKGGYVRSIARDLGA 189

Query: 221 LLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPLESLLVH 280
            LG  GH++ELRR+ SG     DG +T+  V   + L  T + +SYLR    PLE  L  
Sbjct: 190 ALGCYGHVRELRRIWSGPFEAEDG-ITLEQV---EALAKTPELDSYLR----PLEEGLAD 241

Query: 281 HKRIVIKDSCVNAVCYGAKLMLPGVLRYENDIECGEEVVIMTTKGEAVALAI 332
              +         +  G     PG++ Y  + E G+E    + +G AVA+ I
Sbjct: 242 LPELKCSPEGAQRLRNGN----PGMV-YPGEAEYGDE-AWASFEGRAVAVGI 287

ref|ZP_00199888.1| COG0130: Pseudouridine synthase [Rubrobacter xylanophilus DSM 9941]
(265 aa)

Score: 93 bits (231), Expect: 1.01324e-17
Length: 260, Idn/Pos/Gap = 82/115/46 (31%/44%/17%)

Query:  92 IKRIL-RVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAGKEYVAVLR--------- 141
           +KR+L R  K GH+GTLDP  +G L++ + RATRL +      K YVA  R         
Sbjct:   1 MKRLLPRRTKVGHTGTLDPLASGLLVLLVGRATRLSRYVTGLDKTYVATARFGAASDTLD  60

Query: 142 -----LHGMRPELDEATVRRAIETLTGPLYQRPPLISAVK-----------------RQL 179
                L    P  DEA +RRA+    G + Q PP+ SAV+                 R+ 
Sbjct:  61 ADGEILENAGPVPDEAELRRALPRFVGEIRQLPPMASAVRVGGRRLYELHRRGVEVEREP 120

Query: 180 RIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVH 239
           R+  ++  +LL +DP      F VSC +GTY+RTL   L   LG   ++  LRR R    
Sbjct: 121 RLVRVHSLELLSFDPPA--ATFAVSCSSGTYVRTLISDLAASLGTAAYLTALRRTRV--- 175

Query: 240 SEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPLESLLVHHKRIVIKDSCVNAVCYGAK 299
               G + + D L  Q L     D S +   I P   +L H   +   +    AV  G  
Sbjct: 176 ----GHLRVEDALPPQDL-----DPSTIHHRIIPPSGVLAHLPAVEADEGRARAVASGRG 226

Query: 300 LMLPGVLRYENDIECGEEVV 319
           L + G L     +E G E++
Sbjct: 227 LRVAGGLEGSFRVERGGELL 246

ref|ZP_00299835.1| COG0130: Pseudouridine synthase [Geobacter metallireducens GS-15]
(304 aa)

Score: 93 bits (231), Expect: 1.09226e-17
Length: 195, Idn/Pos/Gap = 69/92/30 (35%/47%/15%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           G I +DKPA  +SH+++A ++RIL  +K GH+GTLDP  TG L V +   T+ +     A
Sbjct:   3 GFIVIDKPAGLTSHDIIARVRRILGQKKAGHTGTLDPFATGVLPVAMGEGTKAIPFLDEA  62

Query: 133 GKEYVAVLRL---------------HGMRPELDEATVRRAIETLTGPLYQRPPLISAVKR 177
            KEY A + L                G    L    VR       G   Q PP+ SAVK+
Sbjct:  63 VKEYRATMVLGAATDTQDCTGRVEKEGDWTRLSVEAVREVFGAYIGKCKQIPPMYSAVKQ 122

Query: 178 Q--LRIRTIYESKLLEYDPK---------RRLVL----FWVSCEAGTYIRTLCVHLGLLL 222
                 R   +   +E +P+          R+ L    F VSC  GTY+RTL   +G  L
Sbjct: 123 GGVPLYRLARKGHEVEREPRDIEIHSLIIDRMELPRIEFTVSCSRGTYVRTLAHDMGERL 182

Query: 223 GVGGHMQELRRVRSG 237
           G G H+  LRR RSG
Sbjct: 183 GCGAHLSALRRTRSG 197

ref|NP_439441.1| tRNA pseudouridine 55 synthase [Haemophilus influenzae Rd KW20]
gb|AAC22938.1| tRNA pseudouridine 55 synthase (truB) [Haemophilus influenzae Rd KW20]
sp|P45142|TRUB_HAEIN tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(312 aa)

Score: 93 bits (230), Expect: 1.19725e-17
Length: 193, Idn/Pos/Gap = 63/91/35 (32%/47%/18%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           GV  LDKP   SS++++  +KR+ +  K GH+G LDP  TG L +C+  AT+  +    A
Sbjct:  13 GVFLLDKPQGMSSNDIMQKVKRLFQANKAGHTGALDPLATGMLPICLGEATKFSQFLLDA  72

Query: 133 GKEYVAVLRLHGMRPELDEA---------------TVRRAIETLTGPLYQRPPLISAVK- 176
            K Y+   +L G R +  +A                +  A+E   G + Q P + SA+K 
Sbjct:  73 DKRYLVTAKL-GERTDTSDAEGQVVETREVNLETQQILTALEQFRGDILQVPTMFSALKH 131

Query: 177 ----------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGL 220
                           R+ R  TI+E   +EY+     +   V C  GTYIRTL   LG 
Sbjct: 132 NGKPLYEYARQGITVEREARPITIFELNFIEYNAP--FLTLEVHCSKGTYIRTLVDDLGE 189

Query: 221 LLGVGGHMQELRR 233
           +LG G H+  LRR
Sbjct: 190 VLGCGAHVTMLRR 202

ref|ZP_00210625.1| COG0130: Pseudouridine synthase [Ehrlichia canis str. Jake]
(301 aa)

Score: 93 bits (230), Expect: 1.23788e-17
Length: 227, Idn/Pos/Gap = 69/106/37 (30%/46%/16%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           G +NLDKP   SS   V  +KRIL V+K GH+GTLDP  +G L + I  AT+++      
Sbjct:   3 GWVNLDKPCGMSSALAVNLVKRILNVKKAGHAGTLDPLASGVLPIAIGEATKVMPYAVDV  62

Query: 133 GKEYVAVLRLHGMRPELDEA---------------TVRRAIETLTGPLYQRPPLISA--- 174
            K Y+  ++  G +   D+A                +++ I    G L Q PP  SA   
Sbjct:  63 IKSYLFTVQW-GEQRTTDDAEGEIVDKSDMIPCVENIKKIIPDFIGLLKQVPPSFSAVHV 121

Query: 175 --------------VKRQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGL 220
                         V    R   + E KLL +D +     F++SC  G Y+R++   LG+
Sbjct: 122 NGVRAFELARSGQDVNLSSRFVDVLELKLLSFDVENNKADFYLSCRKGVYVRSIARDLGI 181

Query: 221 LLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYL 267
            LG  G++ +L+RVR G   + +  +T+  +   + L+ T    SYL
Sbjct: 182 KLGCLGYVTKLQRVRVGCFRKKNA-ITLEML---KTLYSTNCKSSYL 224

ref|YP_171038.1| tRNA pseudouridine synthase B [Synechococcus elongatus PCC 6301]
sp|Q5N5A0|TRUB_SYNP6 tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
dbj|BAD78518.1| tRNA pseudouridine synthase B [Synechococcus elongatus PCC 6301]
ref|ZP_00164073.2| COG0130: Pseudouridine synthase [Synechococcus elongatus PCC 7942]
(294 aa)

Score: 92 bits (229), Expect: 1.75741e-17
Length: 199, Idn/Pos/Gap = 75/102/37 (37%/51%/18%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           G +NLDKPA  +SH+ VA ++R+LR  + GH GTLDP VTG L + + RATRL+    S 
Sbjct:   5 GFVNLDKPAGWTSHDCVAKLRRLLRERRIGHGGTLDPAVTGVLPIAVGRATRLLPYLPS-  63

Query: 133 GKEYVAVLRLHGMRPELDEAT------------VRRAIET----LTGPLYQRPPLISAVK 176
           GK YV  +R  G++   D+ T             R AIE       G + Q+PP +SAV+
Sbjct:  64 GKTYVGTIRF-GLQTSTDDLTGDRLAEADTSHLSREAIEAALPQFLGHIQQQPPQVSAVQ 122

Query: 177 RQ------------------LRIRTIYESKLLEYDPKRRLVL-FWVSCEAGTYIRTLCVH 217
            Q                   R   I   ++L++    +  L   + C AGTYIR+L   
Sbjct: 123 VQGQRLYQLARRGEAPTELPWRTVEIQSIRILQWRSGSQAELSVEIHCGAGTYIRSLARD 182

Query: 218 LGLLLGVGGHMQELRRVRS 236
           LG +LGVGG + ELRR  S
Sbjct: 183 LGAVLGVGGTLAELRRTAS 201

ref|ZP_00166981.2| COG0130: Pseudouridine synthase [Ralstonia eutropha JMP134]
(315 aa)

Score: 92 bits (229), Expect: 1.97517e-17
Length: 234, Idn/Pos/Gap = 83/110/42 (35%/47%/17%)

Query:  57 AGYSPLKRPIQEYIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLI 116
           A   P + P +E    GV+ LDKP   SS++ +   KR+LR  K GH+GTLDP  TG L 
Sbjct:   5 ANNRPPRLPRREV--HGVLLLDKPLGLSSNDALVRAKRLLRALKAGHTGTLDPLATGLLP  62

Query: 117 VCIERATRLVKSQQSAGKEYVAVLRLHGM-------------RP-ELDEATVRRAIETLT 162
           +C   AT+  +    A K Y AV+RL                RP   D A +  AI    
Sbjct:  63 LCFGEATKFSQDLLDADKTYEAVVRLGQKTTTGDAEGEVVVERPVSCDRAGLDAAIARFL 122

Query: 163 GPLYQRPPLISAVKRQLRIRTIYE----SKLLEYDPKRRLVL-----------------F 201
           G + Q PP+ SA+K+    R +YE     + +E  P RR+ +                  
Sbjct: 123 GEIDQVPPMHSALKKDG--RPLYEYARAGQTVE-RPARRVTIHAIDVLDCALPLAPSFTM 179

Query: 202 WVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQ 255
            V C  GTYIRTL   +G  LG G H+  LRR+  G     DG VT+ D +DAQ
Sbjct: 180 RVKCSKGTYIRTLAEDIGEALGCGAHLTGLRRIAVG-DLTLDGAVTL-DQIDAQ 231

ref|NP_764503.1| tRNA pseudouridine 5S synthase [Staphylococcus epidermidis ATCC 12228]
ref|YP_188420.1| tRNA pseudouridine synthase B [Staphylococcus epidermidis RP62A]
gb|AAW54207.1| tRNA pseudouridine synthase B [Staphylococcus epidermidis RP62A]
gb|AAO04545.1| tRNA pseudouridine 5S synthase [Staphylococcus epidermidis ATCC 12228]
sp|Q8CMM6|TRUB_STAEP tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
sp|Q5HPS0|TRUB_STAEQ tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(305 aa)

Score: 92 bits (229), Expect: 1.97517e-17
Length: 203, Idn/Pos/Gap = 59/99/37 (29%/48%/18%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           +G++ + K    +SH+VV  +++IL+++K GH+GTLDP+V G L +C+  AT++      
Sbjct:   3 NGILPVFKERGLTSHDVVFKLRKILKMKKIGHTGTLDPEVNGVLPICLGDATKVSDYIME  62

Query: 132 AGKEYVAVLRLHGM-----------------RPELDEATVRRAIETLTGPLYQRPPLISA 174
            GK Y A++ L                    + +++E T+ + ++   G + Q PP+ S+
Sbjct:  63 MGKTYHAMITLGKSTTTEDQTGDILETRAVDKNDINEDTIDQVLQQFEGHIQQIPPMYSS 122

Query: 175 V--------------------KRQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTL 214
           V                    KRQ+ I+ I+    + +  +       V+C  GTYIRTL
Sbjct: 123 VKVNGRKLYEYARNNETVERPKRQVFIKDIHRISEVTFQEQTCHFEVEVTCGKGTYIRTL 182

Query: 215 CVHLGLLLGVGGHMQELRRVRSG 237
              +GL LG   HM  L R+ SG
Sbjct: 183 ATDIGLKLGFPAHMSRLTRIASG 205

ref|ZP_00245504.1| COG0130: Pseudouridine synthase [Rubrivivax gelatinosus PM1]
(345 aa)

Score: 92 bits (228), Expect: 1.99171e-17
Length: 211, Idn/Pos/Gap = 81/107/31 (38%/50%/14%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           GV+ LDKP   SS++ +  +K +LR EK GH+GTLDP  TG L +C   AT+  ++   A
Sbjct:  29 GVLLLDKPLGWSSNDALQKVKGMLRAEKGGHTGTLDPLATGLLPLCFGAATKFSQASLDA  88

Query: 133 GKEYVAVLRLHGMR--------------PELDEATVRRAIETLTGPLYQRPPLISAVKRQ 178
            K Y A L+L   R                 D+A +R A   LTG   Q PP+ SA+KR+
Sbjct:  89 DKTYRATLKLGVTRIGGDGEGEVIETRPVSFDDAALRAACAALTGETMQLPPMHSALKRE 148

Query: 179 LRIRTIYESKLLEYD--PKR----RL-VLFW--------VSCEAGTYIRTLCVHLGLLLG 223
            +    Y    +E +  P+R    RL +L W        V    GTYIRTL   LG  LG
Sbjct: 149 GKALYEYARAGVEVERTPRRVVIHRLDILRWHADELDIEVCVSKGTYIRTLAEDLGRALG 208

Query: 224 VGGHMQELRRVRSGVHSEYDGMVTMHDVLDA 254
            G H+  LRRV SG   + DG +T+ D L A
Sbjct: 209 CGAHLSALRRVASG-PVQLDGAITI-DALQA 237

sp|Q8XJS1|TRUB_CLOPE tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
dbj|BAB81389.1| tRNA-pseudouridine synthase B [Clostridium perfringens str. 13]
ref|NP_562599.1| tRNA-pseudouridine synthase B [Clostridium perfringens str. 13]
(294 aa)

Score: 92 bits (228), Expect: 2.27617e-17
Length: 271, Idn/Pos/Gap = 75/126/52 (27%/46%/19%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           +GVIN+ K    +S +VVA ++R+ +++K GH+GTLDP  +G L VC+ +AT+++     
Sbjct:   2 NGVINIYKNTGMTSFDVVAMVRRVAKMKKVGHTGTLDPAASGVLPVCLGKATKIIDYIME  61

Query: 132 AGKEYVAVLRLHGMRPELD-EATVRR--------------AIETLTGPLYQRPPLISAVK 176
             K Y   L+L  +    D E  V R               I +  G + Q PP+ SA+K
Sbjct:  62 NKKVYRVNLKLGMVTDTYDLEGEVLREEDASHITKDEILNCINSFVGTIDQVPPMYSALK 121

Query: 177 -----------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLG 219
                            R+ R  TIY  + ++ +    + +  V C  GTYIR+LC  +G
Sbjct: 122 QNGVRLYELARQGIEVHREARKITIYSIENIKIESNDNIQMD-VCCSKGTYIRSLCYDIG 180

Query: 220 LLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPLESLLV 279
             L VG  M  L R+++G  ++ +  + + D+            E  L + I  +E  L 
Sbjct: 181 EKLNVGATMTALERIQNGTFTKEEA-INIEDL-----------TEELLEKHIISIEKALD 228

Query: 280 HHKRIVIKDSCVNAVCYGAKLMLPGVLRYEN 310
             ++I + +       +G KL+  GV  ++N
Sbjct: 229 SFEKITVNEK------FG-KLLRNGVKVFDN 252

emb|CAE21597.1| Putative tRNA pseudouridine synthase [Prochlorococcus marinus str. MIT 9313]
sp|P59881|TRUB_PROMM tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
ref|NP_895249.1| Putative tRNA pseudouridine synthase [Prochlorococcus marinus str. MIT 9313]
(320 aa)

Score: 92 bits (228), Expect: 2.51588e-17
Length: 203, Idn/Pos/Gap = 67/101/36 (33%/49%/17%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           G + +DKPA  +SH+ V+ ++R+  +++ GH GTLDP VTG L + +  ATRL+     A
Sbjct:   6 GFVVIDKPAGITSHDCVSRMRRVFGIKRVGHGGTLDPAVTGVLPIALGHATRLLPYLPGA  65

Query: 133 GKEYVAVLRLHGMR----------------PELDEATVRRAIETLTGPLYQRPPLISAVK 176
            K Y   ++L G R                PEL+ A +   +E   G + QRPP +SAV 
Sbjct:  66 -KSYRGSIQL-GQRTSSDDQQGDLISKQAWPELNTAEIEAYLEPFRGRIQQRPPQVSAVH 123

Query: 177 RQ-----------------LRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLG 219
            Q                  R  TI   +LL ++ +   + F V C +GTYIR+L   LG
Sbjct: 124 VQGERAHARARRGETMEIPARTITIDRLQLLNWNQQLGQIDFNVHCSSGTYIRSLARDLG 183

Query: 220 LLLGVGGHMQELRRVRS-GVHSE 241
            L+G G  +  L+R ++ G H +
Sbjct: 184 ELIGCGACLGWLKRTQALGFHEQ 206

ref|ZP_00133989.1| COG0130: Pseudouridine synthase [Actinobacillus pleuropneumoniae serovar 1 str. 4074]
(305 aa)

Score: 92 bits (228), Expect: 2.57965e-17
Length: 300, Idn/Pos/Gap = 80/135/48 (26%/45%/16%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           GV  LDKP   SS++++  +KR+ +  K GH+G LDP  TG L +C+  AT+  +    +
Sbjct:  13 GVFLLDKPQGMSSNDILQKVKRLFQANKAGHTGALDPLATGMLPICLGEATKFSQFLLDS  72

Query: 133 GKEYVAVLRLHGMRPE---------------LDEATVRRAIETLTGPLYQRPPLISAVK- 176
            K Y    +L G R +               + EA +  A+E   G + Q P + SA+K 
Sbjct:  73 DKRYQVTAKL-GKRTDTSDAEGQVVETRAVNVGEAEIITALEQFRGDILQVPTMFSALKH 131

Query: 177 ----------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGL 220
                           R+ R  TI+E + +EY      +   V C  GTYIRTL   LG 
Sbjct: 132 NGKPLYEYARQGITVEREARPITIFELRFIEYAAP--YLTLEVHCSKGTYIRTLVDDLGE 189

Query: 221 LLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPLESLLVH 280
           +LG G H+  LRR+    +     +  M    D Q L +    E  L + + PL++ +  
Sbjct: 190 VLGCGAHVTVLRRLAVANYP----IEAMMSYADLQNLSENQPLEE-LDKYLLPLDTAVES 244

Query: 281 HKRIVIKDSCVNAVCYGAKLMLPGVLRYENDIECGEEVVIMTTKGEAVALAIAHMSTSEI 340
             ++ +      AV +G +      +++EN+ +   +V + +   +   L +A ++T  +
Sbjct: 245 LPKLNLTAEQTKAVGFGQR------VKFENNDQIYGQVRLFSHNMQ--FLGVAEITTDNV 296

ref|ZP_00321339.1| COG0130: Pseudouridine synthase [Haemophilus influenzae 86-028NP]
(306 aa)

Score: 92 bits (227), Expect: 2.85131e-17
Length: 193, Idn/Pos/Gap = 63/90/35 (32%/46%/18%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           GV  LDKP   SS++++  +KR+ +  K GH+G LDP  TG L +C+  AT+  +    A
Sbjct:  13 GVFLLDKPQGMSSNDIMQKVKRLFQANKAGHTGALDPLATGMLPICLGEATKFSQFLLDA  72

Query: 133 GKEYVAVLRLHGMRPELDEA---------------TVRRAIETLTGPLYQRPPLISAVK- 176
            K Y+   +L G R +  +A                +  A+E   G + Q P + SA+K 
Sbjct:  73 DKRYLVTAKL-GERTDTSDAEGQVVETREVHVETPQILTALEQFRGDILQVPTMFSALKH 131

Query: 177 ----------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGL 220
                           R+ R  TI+E   +EY      +   V C  GTYIRTL   LG 
Sbjct: 132 NGKPLYEYARQGITVEREARPITIFELNFIEYHAP--FLTLEVHCSKGTYIRTLVDDLGE 189

Query: 221 LLGVGGHMQELRR 233
           +LG G H+  LRR
Sbjct: 190 VLGCGAHVTMLRR 202

ref|ZP_00286172.1| COG0130: Pseudouridine synthase [Enterococcus faecium]
(333 aa)

Score: 92 bits (227), Expect: 3.15157e-17
Length: 266, Idn/Pos/Gap = 81/119/46 (30%/44%/17%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           G++ L K    +SH+ V  +++IL  +K GH GTLDP V G L +CI +AT++++    +
Sbjct:  29 GLLPLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGVLPICIGKATKVIEYLTDS  88

Query: 133 GKEYVAVLRL---------HGMRPE-------LDEATVRRAIETLTGPLYQRPPLISAVK 176
           GK YV  + L          G R E       L E  +   + +  G + Q PP+ SAVK
Sbjct:  89 GKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEKKIDEVMASFIGEITQIPPMYSAVK 148

Query: 177 --------------------RQLRIRTIYESKLLEYDPKRRLV--LFWVSCEAGTYIRTL 214
                               R+ +I     +  L  D     +   F V C  GTY+RTL
Sbjct: 149 VNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDEVTGTISWRFEVECGKGTYVRTL 208

Query: 215 CVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPL 274
            V  G  LG   HM +L R  S   S+ D + T+ +V  AQ + + T D+  L     P+
Sbjct: 209 AVDTGKKLGYPAHMSDLTRTASAGMSQKDAL-TLEEV--AQAVKNGTIDDCLL-----PI 260

Query: 275 ESLLVHHKRIVIKDSCVNAVCYGAKL 300
           E  +   KR+ I D     V  G +L
Sbjct: 261 EKGVERFKRVDITDEVWQKVKNGMRL 286

emb|CAD14993.1| PROBABLE TRNA PSEUDOURIDINE SYNTHASE B PROTEIN [Ralstonia solanacearum]
sp|Q8XZV4|TRUB_RALSO tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
ref|NP_519412.1| PROBABLE TRNA PSEUDOURIDINE SYNTHASE B PROTEIN [Ralstonia solanacearum GMI1000]
(314 aa)

Score: 92 bits (227), Expect: 3.23146e-17
Length: 292, Idn/Pos/Gap = 90/131/52 (30%/44%/17%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           GV+ LDKP   SS++ +   KR+L  +K GH+GTLDP  TG L +C   AT+  +    A
Sbjct:  19 GVLLLDKPIGWSSNDALIRAKRLLWAKKAGHTGTLDPLATGLLPLCFGEATKFSQDLLEA  78

Query: 133 GKEYVAVLRLHGMRPELDEA---------------TVRRAIETLTGPLYQRPPLISAVK- 176
            K Y AV+RL G+R    +A                +R AI    G + Q PP+ SA+K 
Sbjct:  79 DKTYEAVVRL-GIRTSTADAEGEVLSERPVAVTPEQLRAAIGRFVGEIDQVPPMHSALKK 137

Query: 177 -------------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVH 217
                              R++ IR I +    + D     V   V C  GTYIRTL   
Sbjct: 138 DGKPLYEYARAGQTVERAARRVTIRAI-DVLATDLDAAAPTVTLRVCCSKGTYIRTLGED 196

Query: 218 LGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPLESL 277
           LG  LG G H+  LRR + G  +  DG VT+ + L+A         E     ++ P+++L
Sbjct: 197 LGEALGCGAHLVALRRTQVGSLT-LDGAVTL-EALEA-------ASEDQRAALLAPVDAL 247

Query: 278 LVHHKRIVIKDSCVNAVCYGAKLMLPGVLRYENDIECGEEVVIMTTKGEAVA 329
           L    R+ +         +G +L L      +  +   E+V +   +GEA A
Sbjct: 248 LQTLPRVELGAEDSRRFLHGQRLPL------QLSLPSAEQVRVYGARGEAGA 293

ref|ZP_00141184.2| COG0130: Pseudouridine synthase [Pseudomonas aeruginosa UCBPP-PA14]
(304 aa)

Score: 91 bits (226), Expect: 3.75512e-17
Length: 197, Idn/Pos/Gap = 66/94/33 (33%/47%/16%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           SG++ LDKP   SS++ +  ++ +L  EK GH+G+LDP  TG L +C   AT+  +    
Sbjct:  12 SGILVLDKPRGMSSNQALQKVRWLLNAEKAGHTGSLDPLATGVLPLCFGEATKFSQYLLD  71

Query: 132 AGKEYVAVLRL---------HGMRPELDEATVRR-----AIETLTGPLYQRPPLISAVK- 176
           A K Y  V+R+          G      + TV R     A+    G + Q PP+ SA+K 
Sbjct:  72 ADKGYETVMRMGITTTTGDAEGELLAERDVTVGRDDLEQALPRFRGDIEQVPPMYSALKK 131

Query: 177 ----------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGL 220
                           R+ R  TI    LL ++P        VSC  GTY+RTL   LG 
Sbjct: 132 DGQPLYKLARAGEVVEREARSVTITRLDLLSFEPP--CATLAVSCSKGTYVRTLVEDLGQ 189

Query: 221 LLGVGGHMQELRRVRSG 237
           +LG G H+  LRR ++G
Sbjct: 190 VLGCGAHVAALRRTQAG 206

ref|NP_253430.1| tRNA pseudouridine 55 synthase [Pseudomonas aeruginosa PAO1]
gb|AAG08128.1| tRNA pseudouridine 55 synthase [Pseudomonas aeruginosa PAO1]
sp|P72154|TRUB_PSEAE tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase) (Osmoprotectant regulator of PLC) (ORP protein)
(304 aa)

Score: 91 bits (226), Expect: 3.75512e-17
Length: 197, Idn/Pos/Gap = 66/94/33 (33%/47%/16%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           SG++ LDKP   SS++ +  ++ +L  EK GH+G+LDP  TG L +C   AT+  +    
Sbjct:  12 SGILVLDKPRGMSSNQALQKVRWLLNAEKAGHTGSLDPLATGVLPLCFGEATKFSQYLLD  71

Query: 132 AGKEYVAVLRL---------HGMRPELDEATVRR-----AIETLTGPLYQRPPLISAVK- 176
           A K Y  V+R+          G      + TV R     A+    G + Q PP+ SA+K 
Sbjct:  72 ADKGYETVMRMGITTTTGDAEGELLAERDVTVGRDDLEQALPRFRGDIEQVPPMYSALKK 131

Query: 177 ----------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGL 220
                           R+ R  TI    LL ++P        VSC  GTY+RTL   LG 
Sbjct: 132 DGQPLYKLARAGEVVEREARSVTITRLDLLSFEPP--CATLAVSCSKGTYVRTLVEDLGQ 189

Query: 221 LLGVGGHMQELRRVRSG 237
           +LG G H+  LRR ++G
Sbjct: 190 VLGCGAHVAALRRTQAG 206

ref|ZP_00154924.2| COG0130: Pseudouridine synthase [Haemophilus influenzae R2846]
(306 aa)

Score: 91 bits (226), Expect: 3.91509e-17
Length: 193, Idn/Pos/Gap = 63/90/35 (32%/46%/18%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           GV  LDKP   SS++++  +KR+ +  K GH+G LDP  TG L +C+  AT+  +    A
Sbjct:  13 GVFLLDKPQGMSSNDIMQKVKRLFQANKAGHTGALDPLATGMLPICLGEATKFSQFLLDA  72

Query: 133 GKEYVAVLRLHGMRPELDEA---------------TVRRAIETLTGPLYQRPPLISAVK- 176
            K Y+   +L G R +  +A                +  A+E   G + Q P + SA+K 
Sbjct:  73 DKRYLVTAKL-GERTDTSDAEGQVVETREVHVETPQILTALEQFRGDILQVPTMFSALKH 131

Query: 177 ----------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGL 220
                           R+ R  TI+E   +EY      +   V C  GTYIRTL   LG 
Sbjct: 132 NGKPLYEYARQGITVEREARPITIFELNFIEYHAP--FLTLEVHCSKGTYIRTLVDDLGE 189

Query: 221 LLGVGGHMQELRR 233
           +LG G H+  LRR
Sbjct: 190 VLGCGAHVTMLRR 202

ref|ZP_00157355.2| COG0130: Pseudouridine synthase [Haemophilus influenzae R2866]
(306 aa)

Score: 91 bits (226), Expect: 3.9479e-17
Length: 193, Idn/Pos/Gap = 63/90/35 (32%/46%/18%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           GV  LDKP   SS++++  +KR+ +  K GH+G LDP  TG L +C+  AT+  +    A
Sbjct:  13 GVFLLDKPQGMSSNDIMQKVKRLFQANKAGHTGALDPLATGMLPICLGEATKFSQFLLDA  72

Query: 133 GKEYVAVLRLHGMRPELDEA---------------TVRRAIETLTGPLYQRPPLISAVK- 176
            K Y+   +L G R +  +A                +  A+E   G + Q P + SA+K 
Sbjct:  73 DKRYLVTAKL-GERTDTSDAEGQVVETREVNLETPQILTALEQFRGDILQVPTMFSALKH 131

Query: 177 ----------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGL 220
                           R+ R  TI+E   +EY      +   V C  GTYIRTL   LG 
Sbjct: 132 NGKPLYEYARQGITVEREARPITIFELNFIEYHAP--YLTLEVHCSKGTYIRTLVDDLGE 189

Query: 221 LLGVGGHMQELRR 233
           +LG G H+  LRR
Sbjct: 190 VLGCGAHVTMLRR 202

gb|AAP96263.1| tRNA pseudouridine synthase B [Haemophilus ducreyi 35000HP]
ref|NP_873874.1| tRNA pseudouridine synthase B [Haemophilus ducreyi 35000HP]
sp|P59878|TRUB_HAEDU tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(305 aa)

Score: 91 bits (225), Expect: 5.6991e-17
Length: 194, Idn/Pos/Gap = 65/89/35 (33%/45%/18%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           GV  LDKP   SS+EV+  +KR  +  K GH+G LDP  TG L +C+  AT+  +    +
Sbjct:  13 GVFLLDKPQGMSSNEVLQKVKRFYQANKAGHTGALDPLATGMLPICLGEATKFSQFLLDS  72

Query: 133 GKEYVAVLRLHGMRPE---------------LDEATVRRAIETLTGPLYQRPPLISAVK- 176
            K Y+   +L G R +               L E  +   +   TG L Q P + SA+K 
Sbjct:  73 DKRYIVTAKL-GERTDTSDAEGELVESREVSLTEKDILAILPQFTGDLLQVPTMFSALKH 131

Query: 177 ----------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGL 220
                           R+ R  TI+E K + Y+     +   V C  GTYIRTL   LG 
Sbjct: 132 QGKPLYEYARQSITIEREARPITIFELKFISYEAP--YLTLEVHCSKGTYIRTLIDDLGE 189

Query: 221 LLGVGGHMQELRRV 234
            LG G H+  LRR+
Sbjct: 190 KLGCGAHVAILRRL 203

ref|NP_931691.1| tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (pseudouridylate synthase) (uracil hydrolyase) (P35 protein) [Photorhabdus luminescens subsp. laumondii TTO1]
emb|CAE16899.1| tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (pseudouridylate synthase) (uracil hydrolyase) (P35 protein) [Photorhabdus luminescens subsp. laumondii TTO1]
sp|Q7MAY1|TRUB_PHOLL tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(315 aa)

Score: 90 bits (224), Expect: 6.79052e-17
Length: 248, Idn/Pos/Gap = 71/114/42 (28%/45%/16%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           GV+ LDKP + SS++ +  +KRI    K GH+G LDP  TG L VC+  AT+  +    +
Sbjct:  12 GVLLLDKPQDISSNDALQKVKRIFNASKAGHTGALDPLATGMLPVCLGEATKFSQFLLDS  71

Query: 133 GKEYVAVLRL---------HGM-----RPELDEATVRRAIETLTGPLYQRPPLISAVK-- 176
            K Y  + RL         HG        +L +  +  A++   G   Q P + SA+K  
Sbjct:  72 DKRYRVIARLGQRTDTSDSHGQIISERAIQLSQVQLDAALDKFRGDTMQIPSMYSALKYQ 131

Query: 177 ---------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLL 221
                          R+ R  T+YE + + ++     +   + C  GTYIRT+   LG L
Sbjct: 132 GKPLYEYARQGIEVEREARPITVYELQFIRWENDE--LELEIHCSKGTYIRTIIDDLGEL 189

Query: 222 LGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDE-----SYLRRVIKPLES 276
           LG G H+  LRR++   +   D MVT+  + + Q      KD+       +  ++ P++S
Sbjct: 190 LGCGAHVIYLRRLQVANYPN-DRMVTLEQLYELQ---KQAKDQEIPVGELIDSLLLPMDS 245

Query: 277 LLVHHKRI 284
            + H   +
Sbjct: 246 AIAHFPEV 253

ref|YP_047802.1| tRNA pseudouridine 55 synthase [Acinetobacter sp. ADP1]
emb|CAG69980.1| tRNA pseudouridine 55 synthase [Acinetobacter sp. ADP1]
sp|Q6F7I5|TRUB_ACIAD tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(318 aa)

Score: 90 bits (223), Expect: 7.89093e-17
Length: 207, Idn/Pos/Gap = 63/98/39 (30%/47%/18%)

Query:  63 KRPIQEYIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERA 122
           +RP+     SGV  L+KP   SS+ V+  ++ + R +K GH+G LDP  TG L +C+  A
Sbjct:  27 RRPV-----SGVFLLNKPLGLSSNGVLQKVRWLFRAQKAGHTGALDPLATGLLPICLGEA  81

Query: 123 TRLVKSQQSAGKEYVAVLRLHGMR---------------PELDEATVRRAIETLTGPLYQ 167
           T+       + K Y  V++L  +                P L    +   ++   G + Q
Sbjct:  82 TKFSHYLLDSTKRYQTVVKLGQVTTTGDVEGKVVQSRSVPPLTRDMLELVLDGFRGDIQQ 141

Query: 168 RPPLISAVK-----------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTY 210
            PP+ SA+K                 R+ R  TI+  KL+++D +   +   V+C  GTY
Sbjct: 142 VPPMYSALKRDGRPLYELARQGIEIEREARPVTIHALKLVDFDTES--LTLDVTCSKGTY 199

Query: 211 IRTLCVHLGLLLGVGGHMQELRRVRSG 237
           IR L   +G  LG GGH+  L RV++G
Sbjct: 200 IRVLGEDIGEALGCGGHLTALHRVQTG 226

gb|AAO10114.1| Pseudouridine synthase [Vibrio vulnificus CMCP6]
ref|NP_760587.1| Pseudouridine synthase [Vibrio vulnificus CMCP6]
ref|NP_935499.1| pseudouridine synthase [Vibrio vulnificus YJ016]
sp|Q8DBV8|TRUB_VIBVU tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
sp|Q7MI11|TRUB_VIBVY tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
dbj|BAC95470.1| pseudouridine synthase [Vibrio vulnificus YJ016]
(314 aa)

Score: 90 bits (223), Expect: 8.943e-17
Length: 244, Idn/Pos/Gap = 77/113/45 (31%/46%/18%)

Query:  64 RPIQEYIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERAT 123
           RPI      GVI LDKP   SS++ +  +KR+   EK GH+G LDP  TG L +C+  AT
Sbjct:   8 RPI-----DGVILLDKPTGMSSNDALQKVKRLYFAEKAGHTGALDPLATGMLPICLGEAT  62

Query: 124 RLVKSQQSAGKEYVAVLRLHGMRPELDEA---------------TVRRAIETLTGPLYQR 168
           +  +    + K Y  + +L G R +  ++               T+   IE   G   Q 
Sbjct:  63 KFSQFLLDSDKRYRVIAKL-GERTDTSDSDGDVVETRPVNVTLETLEACIEKFRGESDQV 121

Query: 169 PPLISAVK-----------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYI 211
           P + SA+K                 R+ R  T+YE  L  ++ +   V   V C  GTYI
Sbjct: 122 PSMFSALKYQGKPLYEYARKGIEVPRESRKITVYEITLHRFEGEE--VEMEVHCSKGTYI 179

Query: 212 RTLCVHLGLLLGVGGHMQELRRVRSGVHS-EYDGMVTMHDVLDAQWLFDTTKDESYLRRV 270
           RT+   LG +LG G H+  LR  R+GV    Y+ MVT+  +   + + +  +D    R V
Sbjct: 180 RTIVDDLGEMLGCGAHVTMLR--RTGVAKYPYENMVTLEQL--NELVDNANRDGVAPREV 235

Query: 271 IKPL 274
           + PL
Sbjct: 236 LDPL 239

ref|NP_884128.1| tRNA pseudouridine synthase B [Bordetella parapertussis 12822]
emb|CAE37165.1| tRNA pseudouridine synthase B [Bordetella parapertussis]
sp|P59874|TRUB_BORPA tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(244 aa)

Score: 90 bits (222), Expect: 1.15829e-16
Length: 208, Idn/Pos/Gap = 68/97/33 (32%/46%/15%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           GV+ LDKP   SS+  +   KR +   K GH+GTLDP  TG L+ C+ RAT++      A
Sbjct:  11 GVLLLDKPVGLSSNHALQRAKRTVDAAKAGHTGTLDPFATGLLVCCMGRATKISGRMLEA  70

Query: 133 GKEYVAVLR-------------LHGMRPE----LDEATVRRAIETLTGPLYQRPPLISAV 175
            K Y A+L+             +    P+    ++EA +R  +    G + Q PP+ SA+
Sbjct:  71 DKTYQAMLQFGEETDSGDLTGHIVARAPDGFAGVEEAALRDVLSRFVGTIEQIPPMYSAL 130

Query: 176 KRQLRIRTIYESKLLEYD-PKRRLVL--------------FWVSCEAGTYIRTLCVHLGL 220
           KR  +    Y    +E D P R++ +                V+C  GTYIRTL   +G 
Sbjct: 131 KRDGKPLYEYARAGIELDRPPRQVTIRHIELLSFSGMQAQIDVACSKGTYIRTLAQDIGR 190

Query: 221 LLGVGGHMQELRRVRSGVHSEYDGMVTM 248
            LG   H+  LRR   G  S  D  VT+
Sbjct: 191 ALGCHAHLAALRRTHVGPFS-LDRAVTL 217

ref|YP_069025.1| tRNA pseudouridine synthase B [Yersinia pseudotuberculosis IP 32953]
ref|NP_668027.1| tRNA pseudouridine 5S synthase [Yersinia pestis KIM]
gb|AAS60859.1| tRNA pseudouridine synthase B [Yersinia pestis biovar Medievalis str. 91001]
ref|NP_991982.1| tRNA pseudouridine synthase B [Yersinia pestis biovar Medievalis str. 91001]
emb|CAH19722.1| tRNA pseudouridine synthase B [Yersinia pseudotuberculosis IP 32953]
emb|CAC92723.1| tRNA pseudouridine synthase B [Yersinia pestis CO92]
gb|AAM84278.1| tRNA pseudouridine 5S synthase [Yersinia pestis KIM]
ref|NP_406953.1| tRNA pseudouridine synthase B [Yersinia pestis CO92]
sp|Q8ZBC4|TRUB_YERPE tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
sp|Q66F58|TRUB_YERPS tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(324 aa)

Score: 89 bits (221), Expect: 1.30181e-16
Length: 210, Idn/Pos/Gap = 66/102/32 (31%/48%/15%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           +GV+ LDKP   SS++V+  +KR+    + GH+G LDP  TG L +C+  AT+  +    
Sbjct:  12 NGVLLLDKPLGLSSNDVLQKVKRLFSANRAGHTGALDPLATGMLPICLGEATKFSQFLLD  71

Query: 132 AGKEYVAVLRLHGMRPE---------------LDEATVRRAIETLTGPLYQRPPLISAVK 176
           + K Y  V RL G R +               L +A +  A+E+  G   Q P + SA+K
Sbjct:  72 SDKRYRVVARL-GQRTDTSDAEGALISEREVNLTQAQIDTALESFRGESQQIPSMYSALK 130

Query: 177 RQLRIRTIYESKLLEYDPKRR-------LVLFW--------VSCEAGTYIRTLCVHLGLL 221
            Q +    Y  + +E + + R       L + W        + C  GTYIRT+   LG L
Sbjct: 131 HQGKPLYEYARQGIEVEREARSITVYELLFIRWEGNDLELEIHCSKGTYIRTIIDDLGEL 190

Query: 222 LGVGGHMQELRRVRSGVHSEYDGMVTMHDV 251
           LG G H+  LRR++   +   + MVT+  +
Sbjct: 191 LGCGAHVSYLRRLQVATYPS-ERMVTLEQL 219

gb|AAP98262.1| tRNA pseudouridine 55 synthase [Chlamydophila pneumoniae TW-183]
ref|NP_300378.1| tRNA pseudouridine synthase [Chlamydophila pneumoniae J138]
gb|AAF38278.1| tRNA pseudouridine synthase B [Chlamydophila pneumoniae AR39]
ref|NP_876605.1| tRNA pseudouridine 55 synthase [Chlamydophila pneumoniae TW-183]
ref|NP_224524.1| tRNA Pseudouridine Synthase [Chlamydophila pneumoniae CWL029]
sp|Q9Z8L9|TRUB_CHLPN tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
dbj|BAA98529.1| tRNA pseudouridine synthase [Chlamydophila pneumoniae J138]
gb|AAD18468.1| tRNA Pseudouridine Synthase [Chlamydophila pneumoniae CWL029]
ref|NP_444986.1| tRNA pseudouridine synthase B [Chlamydophila pneumoniae AR39]
(235 aa)

Score: 89 bits (221), Expect: 1.36864e-16
Length: 202, Idn/Pos/Gap = 65/97/33 (32%/48%/16%)

Query:  70 IRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERA-TRLVKS 128
           ++ G++ +DKP   +S  ++  + +++ V+K GH+GTLDP  TG +++ I R  TRL   
Sbjct:   7 LKEGILLVDKPQGRTSFSLIRALTKLIGVKKIGHAGTLDPFATGVMVMLIGRKFTRLSDI  66

Query: 129 QQSAGKEYVAVLRLHGMR----------------PELDEATVRRAIETLTGPLYQRPPLI 172
                KEY A+  L                    P L+E  V  A E   G + Q PP+ 
Sbjct:  67 LLFEDKEYEAIAHLGTTTDSYDCDGKVVGRSKKIPSLEE--VLSAAEYFQGEIQQLPPMF 124

Query: 173 SAVKRQLRIRTIYESKLLEYDPKRR--------------LVLFWVSCEAGTYIRTLCVHL 218
           SA K Q +    Y  K L  +                  L+ F VSC  GTYIR++   L
Sbjct: 125 SAKKVQGKKLYEYARKGLSIERHHSTVQVHLQITKYEYPLLHFVVSCSKGTYIRSIAHEL 184

Query: 219 GLLLGVGGHMQELRRVRSGVHS 240
           G +LG G ++++LRR+RSG  S
Sbjct: 185 GTMLGCGAYLEQLRRLRSGRFS 206

ref|YP_180216.1| putative tRNA pseudouridine synthase B [Ehrlichia ruminantium str. Welgevonden]
emb|CAI26853.1| tRNA pseudouridine synthase B [Ehrlichia ruminantium str. Welgevonden]
emb|CAI27807.1| tRNA pseudouridine synthase B [Ehrlichia ruminantium str. Gardel]
emb|CAH58072.1| putative tRNA pseudouridine synthase B [Ehrlichia ruminantium str. Welgevonden]
ref|YP_196281.1| tRNA pseudouridine synthase B [Ehrlichia ruminantium str. Gardel]
ref|YP_197235.1| tRNA pseudouridine synthase B [Ehrlichia ruminantium str. Welgevonden]
sp|Q5HBH8|TRUB_EHRRW tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
sp|Q5FHK7|TRUB_EHRRG tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(296 aa)

Score: 89 bits (221), Expect: 1.4389e-16
Length: 198, Idn/Pos/Gap = 58/93/35 (29%/46%/17%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           G IN+DKP   SS  VV+ +K+IL V+K G++GTLDP  +G L + I  AT+L+      
Sbjct:   3 GWINIDKPCGISSASVVSRVKKILNVKKVGYAGTLDPLASGILPIAIGEATKLMPYAVDV  62

Query: 133 GKEYV----------------AVLRLHGMRPELDEATVRRAIETLTGPLYQRPPLISAV- 175
            K Y+                 +++   + P  +E  + + I    G + Q PP  SA+ 
Sbjct:  63 QKSYIFTVQWGEQRTTDDASGEIIKKSNIVPHFEE--INKIIPNFIGMIEQVPPNFSAIH 120

Query: 176 ----------------KRQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLG 219
                           +   R   +   KLL +  +     F++ C+ G Y+R++   LG
Sbjct: 121 VDGVRAFKLARNGQEFELSSRYVNVVRLKLLSFSRENNTADFYLLCKKGVYVRSIARDLG 180

Query: 220 LLLGVGGHMQELRRVRSG 237
           + LG  G++ +LRRVR G
Sbjct: 181 IRLGCFGYVAKLRRVRVG 198

ref|ZP_00219099.1| COG0130: Pseudouridine synthase [Burkholderia cepacia R1808]
(300 aa)

Score: 89 bits (221), Expect: 1.46311e-16
Length: 266, Idn/Pos/Gap = 82/122/46 (30%/45%/17%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           GV+ LDKP   SS++ +   KR+L  +K GH+GTLDP  +G L +C   AT+  +    A
Sbjct:   8 GVLLLDKPVGLSSNDALIRAKRLLLAKKAGHTGTLDPLASGLLPLCFGEATKFSQDLLEA  67

Query: 133 GKEYVAVLRLHGMRPELDEATVRRAIET----------------LTGPLYQRPPLISAVK 176
            K Y A +RL G+R    +A     +ET                 TG + Q PP+ SA+K
Sbjct:  68 DKTYEATMRL-GVRTTTGDAE-GDVLETRAVACDRAAVAAALARFTGDIVQVPPMYSALK 125

Query: 177 -----------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLG 219
                            R+ R  TI+   LL  D     V F V+C  GTY+RTL   +G
Sbjct: 126 RDGKPLYEYARAGQTVEREGRNVTIHALDLL--DCALPDVTFRVTCSKGTYVRTLAEDIG 183

Query: 220 LLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPLESLLV 279
             LG G H+  LR  R+GV     G +T+   +    L D    E+     ++P+++LL 
Sbjct: 184 EALGCGAHLTMLR--RTGV-----GALTLEHAVTLDALSDAA--EAARDAWLQPVDALLS 234

Query: 280 HHKRIVIKDSCVNAVCYGAKLMLPGV 305
               + + D+      +G +L L  +
Sbjct: 235 TFPPVRLDDASAKRFLHGQRLPLSAL 260

emb|CAE33736.1| tRNA pseudouridine synthase B [Bordetella bronchiseptica RB50]
emb|CAE41545.1| tRNA pseudouridine synthase B [Bordetella pertussis Tohama I]
ref|NP_880021.1| tRNA pseudouridine synthase B [Bordetella pertussis Tohama I]
ref|NP_889780.1| tRNA pseudouridine synthase B [Bordetella bronchiseptica RB50]
sp|P65853|TRUB_BORBR tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
sp|P65852|TRUB_BORPE tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(244 aa)

Score: 89 bits (221), Expect: 1.46311e-16
Length: 208, Idn/Pos/Gap = 68/96/33 (32%/46%/15%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           GV+ LDKP   SS+  +   KR +   K GH+GTLDP  TG L+ C+ RAT++      A
Sbjct:  11 GVLLLDKPVGLSSNHALQRAKRTVDAAKAGHTGTLDPFATGLLVCCMGRATKISGRMLEA  70

Query: 133 GKEYVAVLR-------------LHGMRPE----LDEATVRRAIETLTGPLYQRPPLISAV 175
            K Y A L+             +    P+    ++EA +R  +    G + Q PP+ SA+
Sbjct:  71 DKTYQATLQFGEETDSGDLTGHIVARAPDGFAGVEEAALRDVLSRFVGTIEQIPPMYSAL 130

Query: 176 KRQLRIRTIYESKLLEYD-PKRRLVL--------------FWVSCEAGTYIRTLCVHLGL 220
           KR  +    Y    +E D P R++ +                V+C  GTYIRTL   +G 
Sbjct: 131 KRDGKPLYEYARAGIELDRPPRQVTIRHIELLSFSGMQAQIDVACSKGTYIRTLAQDIGR 190

Query: 221 LLGVGGHMQELRRVRSGVHSEYDGMVTM 248
            LG   H+  LRR   G  S  D  VT+
Sbjct: 191 ALGCHAHLAALRRTHVGPFS-LDRAVTL 217

ref|ZP_00366138.1| COG0130: Pseudouridine synthase [Streptococcus pyogenes M49 591]
(197 aa)

Score: 89 bits (221), Expect: 1.55111e-16
Length: 201, Idn/Pos/Gap = 65/92/51 (32%/45%/25%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           +G+INL K A  +SH+ V  ++++L+ +K GH GTLDP V G L + + +ATR+++    
Sbjct:   3 NGIINLKKEAGMTSHDAVFKLRKLLQEKKIGHGGTLDPDVVGVLPIAVGKATRVIEYMIE  62

Query: 132 AGKEYVAVLRL----------------HGMRPELDEATVRRAIETLTGPLYQRPPLISAV 175
           AGK Y   + L                  +   L E  V + + T  G + Q PP+ SAV
Sbjct:  63 AGKVYEGQVTLGYSTTTEDASGEVVARSSLPAVLTEELVDQTMTTFLGKITQTPPMYSAV 122

Query: 176 KRQLRIRTIYESKLLEY--------DPKRRLVL--------------------FWVSCEA 207
           K   R       KL EY         P+R + +                    F V+C  
Sbjct: 123 KVNGR-------KLYEYARAGESVERPRREVTISLFERTSPLNFTEDGLCRFSFKVACSK 175

Query: 208 GTYIRTLCVHLGLLLGVGGHM 228
           GTY+RTL V LG  LGV  HM
Sbjct: 176 GTYVRTLAVDLGRALGVESHM 196

ref|ZP_00329264.1| COG0130: Pseudouridine synthase [Moorella thermoacetica ATCC 39073]
(305 aa)

Score: 89 bits (221), Expect: 1.59043e-16
Length: 200, Idn/Pos/Gap = 67/95/36 (33%/47%/18%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           G +N+ KP   +SH+VV  ++R+L+V++ GH GTLDP   G L V +  ATRL++  Q  
Sbjct:   4 GFVNVLKPPGLTSHDVVQNLRRLLKVKRIGHGGTLDPLAAGVLPVAVGTATRLLEYLQGG  63

Query: 133 GKEYVAVLRLHGMR----------------PELDEATVRRAIETLTGPLYQRPPLISA-- 174
            K Y A   L G++                P   E  ++ A    TG + Q PP++SA  
Sbjct:  64 DKAYRAEFIL-GLKTDTQDLGGRVLARKPCPPFTEKDLQAATRPFTGTIRQVPPMVSAVH 122

Query: 175 ---------------VKRQLRIRTIYESKLLEY--DPKRRLVLFWVSCEAGTYIRTLCVH 217
                          V+R  R  TI+E +L+    D      L  ++C  GTYIRTL   
Sbjct: 123 YQGRRLYELAREGLEVERPARQVTIHEFRLIRAWPDGPYYRALIDITCSRGTYIRTLGAD 182

Query: 218 LGLLLGVGGHMQELRRVRSG 237
            G  LGVG  +  L R R+G
Sbjct: 183 WGDYLGVGATLAFLLRTRAG 202

gb|AAF93811.1| tRNA pseudouridine 55 synthase [Vibrio cholerae O1 biovar eltor str. N16961]
ref|NP_230294.1| tRNA pseudouridine 55 synthase [Vibrio cholerae O1 biovar eltor str. N16961]
sp|Q9KU78|TRUB_VIBCH tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(312 aa)

Score: 88 bits (219), Expect: 2.22055e-16
Length: 234, Idn/Pos/Gap = 77/110/38 (32%/47%/16%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           GVI LDKP   SS++ +  +KR+   EK GH+G LDP  TG L +C+  AT+  +    +
Sbjct:  12 GVILLDKPTGISSNDALQKVKRLYGAEKAGHTGALDPLATGMLPICLGEATKFSQFLLDS  71

Query: 133 GKEYVAVLRLH-------------GMRP-ELDEATVRRAIETLTGPLYQRPPLISAVK-- 176
            K Y  + +L                RP  +D  T+   I    G   Q P + SA+K  
Sbjct:  72 DKRYRVIAKLGERTDTSDSDGQVVQTRPVHVDYDTLLACIAKFRGETDQVPSMFSALKYQ 131

Query: 177 ---------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLL 221
                          R+ R  T+YE +L  ++     V   V C  GTYIRT+   LG +
Sbjct: 132 GRPLYEYARQGIEVPREARKITVYEIELHRFEGDE--VEMEVHCSKGTYIRTIVDDLGEM 189

Query: 222 LGVGGHMQELRRVRSGVHS-EYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPL 274
           LG G H+  LRRV  GV +  Y+ MVT+   L+A  +    +DE  +  V+ PL
Sbjct: 190 LGCGAHVTMLRRV--GVANYPYERMVTLEQ-LNA-LVEQAHRDEKAVADVLDPL 239

ref|NP_637859.1| tRNA pseudouridine synthase B [Xanthomonas campestris pv. campestris str. ATCC 33913]
gb|AAM41783.1| tRNA pseudouridine synthase B [Xanthomonas campestris pv. campestris str. ATCC 33913]
sp|Q8P7U9|TRUB_XANCP tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(308 aa)

Score: 88 bits (219), Expect: 2.55895e-16
Length: 195, Idn/Pos/Gap = 65/98/36 (33%/50%/18%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           G++ LDKPA  SS+  +   +R+LR EK GH+G+LDP  TG L +C   AT++      +
Sbjct:  12 GILLLDKPAGLSSNNALQAARRLLRAEKGGHTGSLDPLATGLLPLCFGEATKIAGLLLGS  71

Query: 133 GKEYVAVLRL-----------HGMR----PELDEATVRRAIETLTGPLYQRPPLISAVKR 177
            K Y A + L             +R    P L EA ++ A+    G + Q+ P+ SA+K+
Sbjct:  72 AKAYDAEIVLGVTTDTDDADGQPLRERSVPALSEAALQAALAPFIGRIQQQAPIYSALKQ 131

Query: 178 -------QLRIRTIYESKLLEYD-----------PKRRLVLFWVSCEAGTYIRTLCVHLG 219
                  + R   + E+ + E +           P+ RL    V+C +GTYIR+L   LG
Sbjct: 132 GGEPLYAKARRGEVIEAPVREVEVHAITLTSYASPRLRLR---VTCGSGTYIRSLARDLG 188

Query: 220 LLLGVGGHMQELRRV 234
            +LG G H+  LRRV
Sbjct: 189 EVLGCGAHIAALRRV 203

gb|AAO33771.1| putative tRNA pseudouridine synthase [Oryza sativa (indica cultivar-group)]
(458 aa)

Score: 88 bits (219), Expect: 2.71286e-16
Length: 182, Idn/Pos/Gap = 60/90/32 (32%/49%/17%)

Query:  74 VINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAG 133
           V+ +DKP   +S  V   ++R++ V+K GH+GTLDP  TG LIVC+ +AT++V   Q   
Sbjct: 271 VVLIDKPKGWTSFTVCGKLRRLVNVQKVGHAGTLDPMATGLLIVCVGKATKVVDRYQGMV 330

Query: 134 KEYVAVLRLHGMRPELD---------------EATVRRAIETLTGPLYQRPPLISAVK-- 176
           K Y  V RL       D               +  +R+   +  G ++Q PP+ SA+K  
Sbjct: 331 KGYSGVFRLGEATSTWDADSPVIQREPWEHIKDEDIRKVAASFRGEIWQVPPMFSAIKVG 390

Query: 177 ------RQLRIRTIYES----KLLEYDPKRRL-----VLFWVSCEAGTYIRTLCVHLGLL 221
                 +  R  T+  S     + ++D +R L     ++F V C  GTYIR+LC  LG  
Sbjct: 391 GEKMYDKARRGETVELSPRRISIHQFDIERSLEDRQNLIFRVICSKGTYIRSLCADLGKA 450

Query: 222 LG 223
           LG
Sbjct: 451 LG 452

sp|O34273|TRUB_YEREN tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(309 aa)

Score: 88 bits (218), Expect: 3.02368e-16
Length: 210, Idn/Pos/Gap = 67/99/32 (31%/47%/15%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           +GV+ LDKP   SS++V+  +KR+    + GH+G LDP  TG L +C+  AT+  +    
Sbjct:  12 NGVLLLDKPLGLSSNDVLQKVKRLFSANRAGHTGALDPLATGMLPICLGEATKFSQFLLD  71

Query: 132 AGKEYVAVLRLHGMRPELDEA---------------TVRRAIETLTGPLYQRPPLISAVK 176
           + K Y  V RL G R     A               T   A+++  G   Q P + SA+K
Sbjct:  72 SDKRYRVVARL-GQRTNTSHAEGALISEREDICHTGTDDAALDSHRGSSQQVPSMYSALK 130

Query: 177 RQLRIRTIYESKLLEYDPKRR-------LVLFW--------VSCEAGTYIRTLCVHLGLL 221
            Q +    Y  + +E D + R       L + W        + C  GTYIRT+   LG L
Sbjct: 131 HQGKPLYEYARQGIEVDREARSITVYELLFIRWEGNDLELEIHCSKGTYIRTIIDDLGEL 190

Query: 222 LGVGGHMQELRRVRSGVHSEYDGMVTMHDV 251
           LG G H+  LRR++   +   D MVT+  +
Sbjct: 191 LGCGAHVSYLRRLQVATYPS-DRMVTLEQL 219

ref|NP_213482.1| tRNA pseudouridine 55 synthase [Aquifex aeolicus VF5]
gb|AAC06885.1| tRNA pseudouridine 55 synthase [Aquifex aeolicus VF5]
sp|O66922|TRUB_AQUAE tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(287 aa)

Score: 88 bits (217), Expect: 3.78768e-16
Length: 194, Idn/Pos/Gap = 57/93/31 (29%/47%/15%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           G + +DKP   +S EVV  +K  L+  K GH+GTLDP  TG LI+ I +ATR  +     
Sbjct:   3 GALLIDKPKGITSTEVVERVKEKLKARKAGHTGTLDPIATGLLIILINKATRFSQFFIGM  62

Query: 133 GKEYVAVLR--------------LHGMRPELDEATVRRAIETLTGPLYQRPPLISAVK-- 176
            K Y   ++              +     EL+   ++  +    G + Q PP  SA K  
Sbjct:  63 PKTYRFTVKFGAETDTYDAQGKVVETYEGELNCDKLKEVLNEFRGEILQTPPPFSAKKIK 122

Query: 177 -----------RQLRIR----TIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLL 221
                      +++ ++    T+Y  +LL  +P+ +   F     +G Y+R+L   +G  
Sbjct: 123 GRRAYELARKGKKVELKPVKITVYSLELLSCNPREKEAEFLAEISSGGYVRSLAYDIGKK 182

Query: 222 LGVGGHMQELRRVR 235
           LG+GG+M+ELRR++
Sbjct: 183 LGIGGYMKELRRLK 196

ref|YP_155355.1| tRNA pseudouridine 5S synthase [Idiomarina loihiensis L2TR]
gb|AAV81806.1| tRNA pseudouridine 5S synthase [Idiomarina loihiensis L2TR]
sp|Q5QTZ0|TRUB_IDILO tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(310 aa)

Score: 88 bits (217), Expect: 4.32864e-16
Length: 264, Idn/Pos/Gap = 79/113/41 (29%/42%/15%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           +GV+ L+KP   SS+  +  +KR+   +K GH+G LDP  TG L VC+  AT+  +    
Sbjct:  13 TGVVLLNKPQGMSSNHALQRVKRLYNAQKAGHTGALDPLATGILPVCLGEATKFSQYLLD  72

Query: 132 AGKEYVAVLRLHGMRP---------------ELDEATVRRAIETLTGPLYQRPPLISAVK 176
           A K Y     L G+R                 +D A V  AI+   G   Q P + SA+K
Sbjct:  73 ADKAYRVEATL-GVRTTTSDAEGEVVEEKPVAVDTAKVADAIKQFIGEQDQSPSIYSALK 131

Query: 177 RQLRIRTIYESKLLEYDPKRRL---------------VLFWVSCEAGTYIRTLCVHLGLL 221
            + R    Y  + +E   K R                V   VSC  GTYIRTL   LG L
Sbjct: 132 HEGRPLYYYARQGIEVPKKTRTITVHSIELLNIQDNKVTLQVSCSKGTYIRTLVDDLGQL 191

Query: 222 LGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESY--LRRVIKPLESLLV 279
           LG G H+  L R      +E   MVT+  +       +T  +E Y  L  ++ P + LL 
Sbjct: 192 LGCGAHVSMLHRNAVADIAE-AAMVTLEQL-------ETLAEEGYEGLDALLHPADLLLG 243

Query: 280 HHKRIVIKDSCVNAVCYGAKLMLP 303
               + +  +      +G  + LP
Sbjct: 244 QLPEVTVTQAQTRDFLHGQPIPLP 267

ref|ZP_00325896.1| COG0130: Pseudouridine synthase [Trichodesmium erythraeum IMS101]
(301 aa)

Score: 88 bits (217), Expect: 4.51305e-16
Length: 209, Idn/Pos/Gap = 61/101/40 (29%/48%/19%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           G +NL+KP+  +SH+ VA ++++LR+++ GH GTLDP  TG L + + +ATRL++   S 
Sbjct:   3 GFLNLNKPSGMTSHDCVAKVRKLLRLKRVGHGGTLDPAATGVLPIAVGKATRLLQFLPSE  62

Query: 133 GKEYVAVLRL---------------HGMRPELDEATVRRAIETLTGPLYQRPPLISAVK- 176
            K Y   ++                    PEL  + + + +    G + Q PP  SA++ 
Sbjct:  63 -KAYFGTVKFGIITTTDDLEGEIVQSAPVPELMLSDIEKVLPNFLGKIEQVPPSYSAIQV 121

Query: 177 ---------RQ-------LRIRTIYESKLLEYD----PKRRLVLFWVSCEAGTYIRTLCV 216
                    RQ        RI  ++  K+L++     P+  L    ++C  GTYIR +  
Sbjct: 122 EGKRLYDLARQGKTVEVPTRIVEVFNIKILDWRSGDFPEVDLA---IACGTGTYIRAIAR 178

Query: 217 HLGLLLGVGGHMQELRRVRSGVHSEYDGM 245
            LG  L +GG +  L R+ S   SE + +
Sbjct: 179 DLGRTLSIGGTLAALTRIESSGFSEENSL 207

emb|CAA71695.1| yhbA [Yersinia enterocolitica]
(317 aa)

Score: 88 bits (217), Expect: 4.74474e-16
Length: 210, Idn/Pos/Gap = 67/99/32 (31%/47%/15%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           +GV+ LDKP   SS++V+  +KR+    + GH+G LDP  TG L +C+  AT+  +    
Sbjct:  20 NGVLLLDKPLGLSSNDVLQKVKRLFSANRAGHTGALDPLATGMLPICLGEATKFSQFLLD  79

Query: 132 AGKEYVAVLRLHGMRPELDEA---------------TVRRAIETLTGPLYQRPPLISAVK 176
           + K Y  V RL G R     A               T   A+++  G   Q P + SA+K
Sbjct:  80 SDKRYRVVARL-GQRTNTSHAEGALISEREDICHTGTDDAALDSHRGSSQQVPSMYSALK 138

Query: 177 RQLRIRTIYESKLLEYDPKRR-------LVLFW--------VSCEAGTYIRTLCVHLGLL 221
            Q +    Y  + +E D + R       L + W        + C  GTYIRT+   LG L
Sbjct: 139 HQGKPLYEYARQGIEVDREARSITVYELLFIRWEGNDLELEIHCSKGTYIRTIIDDLGEL 198

Query: 222 LGVGGHMQELRRVRSGVHSEYDGMVTMHDV 251
           LG G H+  LRR++   +   D MVT+  +
Sbjct: 199 LGCGAHVSYLRRLQVATYPS-DRMVTLEQL 227

ref|YP_120265.1| putative tRNA pseudouridine synthase [Nocardia farcinica IFM 10152]
sp|Q5YSE0|TRUB_NOCFA tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
dbj|BAD58901.1| putative tRNA pseudouridine synthase [Nocardia farcinica IFM 10152]
(306 aa)

Score: 88 bits (217), Expect: 4.78449e-16
Length: 200, Idn/Pos/Gap = 68/95/36 (34%/47%/18%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           G++ +DK    +SH+VVA  ++IL   K GH+GTLDP  TG L++ +ERAT+L+      
Sbjct:  16 GLLVVDKDGGMTSHDVVARCRKILGTRKIGHAGTLDPMATGVLVLGVERATKLLGLLTLT  75

Query: 133 GKEYVAVLRLHGMRP---------------ELDEATVRRAIETLTGPLYQRPPLISAVK- 176
            K Y A +RL                     L +A V   +  LTG + Q P  +SA+K 
Sbjct:  76 TKAYTATIRLGSATTTDDAEGEVLTTVPAGHLGDAEVAAGVAALTGDIQQVPATVSAIKI 135

Query: 177 --------------RQLRIRTIYESKLLEYDPKRRLVLF-----WVSCEAGTYIRTLCVH 217
                          +L  R +  S+  E   +R +  F      V C +GTY+R L   
Sbjct: 136 GGERAYARHRAGEQVELAARPVTVSR-FEVLARRDVAGFVDLDVVVECSSGTYVRALARD 194

Query: 218 LGLLLGVGGHMQELRRVRSG 237
           LG  LGVGGH+  LRR R G
Sbjct: 195 LGAALGVGGHLTALRRTRVG 214

ref|ZP_00319809.1| COG0130: Pseudouridine synthase [Oenococcus oeni PSU-1]
(298 aa)

Score: 87 bits (216), Expect: 4.90576e-16
Length: 246, Idn/Pos/Gap = 71/118/51 (28%/47%/20%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           +G++ +DKPA  +S +VVA +++I + ++ GH+GTLDP VTG L++ + +AT+L+   Q 
Sbjct:   3 NGIVLVDKPAGLTSFDVVAKLRKIFQQKQVGHTGTLDPSVTGLLVIVLGKATKLIDYLQE  62

Query: 132 AGKEYVAVLRLHGMRPE-------------LDEATV----RRAIETLTGPLYQRPPLISA 174
             K+Y   L L G++ +             L EA      + A ++  G   Q PP+ SA
Sbjct:  63 NQKQYRGTLIL-GLKTDTQDMDGQVTEMQFLKEAIADFKKKAAFDSFLGSSDQLPPMYSA 121

Query: 175 VK--------------------RQLRIRTIYESKLLEYDPKR--RLVLFWVSCEAGTYIR 212
           VK                    R++++    +    ++D  +    + F  +   GTYIR
Sbjct: 122 VKVGGKHLYELARKGETIERKSRKIKVMEFQQVGGSKFDASKGQEYINFVATVSKGTYIR 181

Query: 213 TLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIK 272
           TL    G  LG+   M  LRR+      E DG    +DV ++  L +    ++  R+ I 
Sbjct: 182 TLIEDFGAKLGLPATMMRLRRI------EADG----YDVKNSINLEEILASKT-PRKFII 230

Query: 273 PLESLL 278
           P+E LL
Sbjct: 231 PMEKLL 236

ref|NP_219597.1| tRNA Pseudouridine Synthase [Chlamydia trachomatis D/UW-3/CX]
gb|AAC67685.1| tRNA Pseudouridine Synthase [Chlamydia trachomatis D/UW-3/CX]
sp|O84096|TRUB_CHLTR tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(241 aa)

Score: 87 bits (216), Expect: 5.28834e-16
Length: 201, Idn/Pos/Gap = 67/97/37 (33%/48%/18%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERA-TRLVKSQQS 131
           GV+ +DKP   +S  ++  + R++ V+K GH+GTLDP  TG +++ I R  TRL      
Sbjct:  10 GVLLVDKPQGRTSFSLIRSLVRLIGVKKIGHAGTLDPFATGVMVMLIGRKFTRLSDIMLF  69

Query: 132 AGKEYVAVLRLHGMR----------------PELDEATVRRAIETLTGPLYQRPPLISAV 175
             KEY AV  L                    P +DE  V        G + Q PP+ SA 
Sbjct:  70 EDKEYAAVAHLGTTTDTYDCDGKIVGRSKKVPTMDE--VLTCTSYFQGEIQQVPPMFSAK 127

Query: 176 KRQ-----------LRIRTIYES-----KLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLG 219
           K Q           L I   + +     +L++Y+  R  + F V C  GTYIR++   LG
Sbjct: 128 KVQGKKLYEYARQGLSIERRFATVTVNLRLVKYEYPR--LHFVVQCSKGTYIRSIAHELG 185

Query: 220 LLLGVGGHMQELRRVRSGVHS 240
            +LG G +++ELRR+RSG  S
Sbjct: 186 NMLGCGAYLEELRRLRSGSFS 206

ref|NP_245693.1| TruB [Pasteurella multocida subsp. multocida str. Pm70]
gb|AAK02840.1| TruB [Pasteurella multocida subsp. multocida str. Pm70]
sp|Q9CMQ7|TRUB_PASMU tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(307 aa)

Score: 87 bits (216), Expect: 6.30109e-16
Length: 193, Idn/Pos/Gap = 62/88/35 (32%/45%/18%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           GV  LDKP   SS++++  +KR+ +  K GH+G LDP  TG L +C+  AT+  +    A
Sbjct:  13 GVFLLDKPQGMSSNDIMQKVKRVFQANKAGHTGALDPLATGMLPICLGEATKFSQFLLDA  72

Query: 133 GKEYVAVLRLHGMRPELDEAT---------------VRRAIETLTGPLYQRPPLISAVK- 176
            K Y    +L G R +  +A                +  A+    G L Q P + SA+K 
Sbjct:  73 DKRYQVTAKL-GERTDTSDAEGQVVETRDVQVDVQDILAALPHFRGNLMQVPTMFSALKH 131

Query: 177 ----------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGL 220
                           R+ R  TI++ + + YD     +   V C  GTYIRTL   LG 
Sbjct: 132 QGKPLYEYARAGITVEREARPITIFDLQFIAYDAP--YLTLEVHCSKGTYIRTLVDDLGE 189

Query: 221 LLGVGGHMQELRR 233
            LG G H+  LRR
Sbjct: 190 YLGCGAHVTVLRR 202

emb|CAH63902.1| tRNA pseudouridine synthase B [Chlamydophila abortus S26/3]
ref|YP_219863.1| tRNA pseudouridine synthase B [Chlamydophila abortus S26/3]
(235 aa)

Score: 87 bits (215), Expect: 6.40713e-16
Length: 202, Idn/Pos/Gap = 60/96/33 (29%/47%/16%)

Query:  70 IRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCI-ERATRLVKS 128
           ++ G++ +DKP   +S  ++  + +++ V+K GH+GTLDP  TG +++ I  R TRL   
Sbjct:   7 LKEGILLIDKPQGRTSFSLIRTLTKLIGVKKIGHAGTLDPFATGVMVMLIGRRFTRLSDV  66

Query: 129 QQSAGKEYVAVLRLHGMRPELD--------------EATVRRAIETLTGPLYQRPPLISA 174
                KEY AV  L       D                 +  A +   G + Q PP+ SA
Sbjct:  67 LLFEDKEYAAVAHLGTTTDSYDCDGKIVGRSKKIPTYEEILEASQYFQGEIQQIPPMFSA 126

Query: 175 VKRQLRIRTIYESKLLEYDPKRR----------------LVLFWVSCEAGTYIRTLCVHL 218
             +++  + +YE        +RR                L+ F + C  GTYIR++   L
Sbjct: 127 --KKVNGKKLYEYARKGLSIERRQSTVQVSLQITKYEYPLLHFSIQCSKGTYIRSIAHEL 184

Query: 219 GLLLGVGGHMQELRRVRSGVHS 240
           G +LG G +++ELRR+RSG  S
Sbjct: 185 GNMLGCGAYLEELRRLRSGSFS 206

ref|NP_664691.1| putative tRNA pseudouridine 55 synthase [Streptococcus pyogenes MGAS315]
gb|AAM79494.1| putative tRNA pseudouridine 55 synthase [Streptococcus pyogenes MGAS315]
(281 aa)

Score: 87 bits (215), Expect: 6.56953e-16
Length: 264, Idn/Pos/Gap = 75/119/60 (28%/45%/22%)

Query:  84 SSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAGKEYVAVLRL- 142
           +SH+ V  ++++L+ +K GH GTLDP V G L + + +ATR+++    AGK Y   + L 
Sbjct:   2 TSHDAVFKLRKLLQEKKIGHGGTLDPDVVGVLPIAVGKATRVIEYMTEAGKVYEGQVTLG  61

Query: 143 ---------------HGMRPELDEATVRRAIETLTGPLYQRPPLISAVKRQLRIRTIYES 187
                            +   L E  V + + T  G + Q PP+ SAVK   R       
Sbjct:  62 YSTTTEDASGEVVARSSLPAVLTEELVDQTMTTFLGKITQTPPMYSAVKVNGR------- 114

Query: 188 KLLEY--------DPKRRLVL--------------------FWVSCEAGTYIRTLCVHLG 219
           KL EY         P+R + +                    F V+C  GTY+RTL V LG
Sbjct: 115 KLYEYARAGESVERPRREVTISLFERTSPLNFTEDGLCRFSFKVACGKGTYVRTLAVDLG 174

Query: 220 LLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPLESLLV 279
             LGV  HM  L+R  S   +  +   T+ ++ D      + ++ S+L     P+E  + 
Sbjct: 175 RALGVESHMSFLQRSASAGLT-LETAYTLGEIAD----MVSKQEMSFLL----PIEYGVA 225

Query: 280 HHKRIVIKDSCVNAVCYGAKLMLP 303
              ++VI D+ +  + +G +L LP
Sbjct: 226 DLPKMVIDDTELTEISFGRRLSLP 249

ref|NP_926636.1| tRNA pseudouridine synthase B [Gloeobacter violaceus PCC 7421]
sp|Q7MBB8|TRUB_GLOVI tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
dbj|BAC91631.1| tRNA pseudouridine synthase B [Gloeobacter violaceus PCC 7421]
(292 aa)

Score: 87 bits (215), Expect: 6.62457e-16
Length: 199, Idn/Pos/Gap = 65/92/35 (32%/46%/17%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           G +NLDKPA  +SH+ +A ++R+L   + GH GTLDP  TG L V + RATRL++   S 
Sbjct:   3 GFLNLDKPAGLTSHDCIARLRRVLGERRIGHGGTLDPAATGVLPVAVGRATRLLRF-LSE  61

Query: 133 GKEYVAVLRL---------------HGMRPELDEATVRRAIETLTGPLYQRPPLISAVKR 177
           GK Y A +R                     +LD   V+  ++   G + Q PP  SA+ +
Sbjct:  62 GKVYRATVRFGLSTDTDDLEGNILADAGAADLDLGRVQVHLQAFRGTISQVPPRYSAIHQ 121

Query: 178 Q--------LRIRTIYESKLLEYDPKRRLVLFW-----------VSCEAGTYIRTLCVHL 218
           +         R   I E      + +   VL W           ++C  GTYIR++   L
Sbjct: 122 EGERLYDLARRGVAIAEIAPRTVEIQALTVLDWYPGHYPELQIEIACSTGTYIRSIARDL 181

Query: 219 GLLLGVGGHMQELRRVRSG 237
           G  LG G  +  L R RSG
Sbjct: 182 GTALGTGATLARLLRTRSG 200

ref|ZP_00173106.2| COG0130: Pseudouridine synthase [Methylobacillus flagellatus KT]
(302 aa)

Score: 87 bits (215), Expect: 6.79249e-16
Length: 210, Idn/Pos/Gap = 63/99/34 (30%/47%/16%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           GV+ LDKP   SS++ +  +KR+ +  K GH+G+LDP  +G L +C+  AT+       A
Sbjct:  12 GVLLLDKPLGISSNQALQMVKRLYQAAKAGHTGSLDPLASGLLPICLGEATKFSHFLLDA  71

Query: 133 GKEYVAVLRLHGMRPELD--------------EATVRRAIETLTGPLYQRPPLISAVK-- 176
            K Y A++ L       D              ++ +   ++ + G + Q PP+ SA+K  
Sbjct:  72 DKSYRALVTLGSTTTTGDVEGEIMTQAPVTVTQSELEAILQDMVGDILQVPPMYSALKHE 131

Query: 177 ---------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLL 221
                          R+ R  TI+   L  +D K+  ++  VSC  GTYIRTL   +G  
Sbjct: 132 GKALYAYAREGVEIPRKPRPVTIHAIALERFDGKQFEMV--VSCSKGTYIRTLAEDIGSR 189

Query: 222 LGVGGHMQELRRVRSGVHSEYDGMVTMHDV 251
           LG G H+  LRR+ +  H      VT+  +
Sbjct: 190 LGCGAHLGGLRRLTTA-HFNLKNAVTIEQL 218

ref|ZP_00380110.1| COG0130: Pseudouridine synthase [Brevibacterium linens BL2]
(305 aa)

Score: 87 bits (215), Expect: 7.44541e-16
Length: 222, Idn/Pos/Gap = 69/98/40 (31%/44%/18%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           GVI  DKP   +SH VV+ I+R     K GH+GTLDP  TG L++ + R T+L+      
Sbjct:   8 GVIVCDKPQGLTSHGVVSRIRRWYGTRKVGHAGTLDPMATGVLVLGLGRGTKLLGYITGV  67

Query: 133 GKEYVAVLRLHGMRPELDEAT------------------VRRAIETLTGPLYQRPPLISA 174
            K Y+A +RL    P  D  +                  +   +  L G + Q P  +SA
Sbjct:  68 SKTYLATIRLGSATPTDDADSEPDLFAEPAALSAVTDDGIAHGVSALRGSIDQVPSAVSA 127

Query: 175 VK-----RQLRIR----TIYESKLLEYDPKRRLVLFW------------VSCEAGTYIRT 213
           +K        R+R     + +++ +E      L   +            V C +GTY+R 
Sbjct: 128 IKVNGQRSYARVRAGEDVVLKARRVEISDFTILATRYSVAQGHIDVDVEVDCSSGTYVRA 187

Query: 214 LCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQ 255
           L   LG  LGV GH+  LRR R G  S  D  V + D LD +
Sbjct: 188 LARDLGGSLGVYGHLTALRRTRVGAFS-LDEAVMIPDDLDIE 228

ref|YP_181704.1| tRNA pseudouridine synthase B [Dehalococcoides ethenogenes 195]
gb|AAW39800.1| tRNA pseudouridine synthase B [Dehalococcoides ethenogenes 195]
(300 aa)

Score: 87 bits (215), Expect: 8.02605e-16
Length: 261, Idn/Pos/Gap = 71/122/38 (27%/46%/14%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           +G++N++KP   +S  VV+ ++ I   +K GH G LDP  TG + V +  ATRL++   S
Sbjct:   2 NGILNINKPPGLTSFGVVSKVRHIYSQKKVGHGGMLDPSATGVIPVFLGSATRLIEYLSS  61

Query: 132 AGKEYVAVLRLHGMRPELD---EATVRRAIETLT------------GPLYQRPPLISAVK 176
             K Y+A + L       D   E T R++ E +T            G + Q PP+ SAVK
Sbjct:  62 VRKTYLAEIELGTETDSYDSEGEITSRKSCEHITADMVRNALPDFLGEITQIPPMYSAVK 121

Query: 177 -RQLRIRTIYESKL-LEYDPKRRLVL-------------FWVSCEAGTYIRTLCVHLGLL 221
            R +R+  +    + +E +P++  +                + C  GTYIR++   LG  
Sbjct: 122 HRGVRLYNLARQGIEVERNPRKAAIYGIEFLGFASPVLRLRIECGHGTYIRSIAFDLGRK 181

Query: 222 LGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPLESLLVHH 281
           LG G +++ L R   G       + T  D+ D     +  +++  L  ++ P E+ + H 
Sbjct: 182 LGCGAYLKTLVRESYGPFH----LTTSLDLAD----LEAAENKGRLADILLPPEAAVGHL 233

Query: 282 KRIVIKDSCVNAVCYGAKLML 302
            RI + D  +  +  G ++ L
Sbjct: 234 PRITLDDESITRLVNGLEIRL 254

ref|YP_201855.1| tRNA pseudouridine synthase B [Xanthomonas oryzae pv. oryzae KACC10331]
gb|AAW76470.1| tRNA pseudouridine synthase B [Xanthomonas oryzae pv. oryzae KACC10331]
sp|Q5GXV1|TRUB_XANOR tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(308 aa)

Score: 87 bits (215), Expect: 8.1611e-16
Length: 215, Idn/Pos/Gap = 66/102/49 (30%/47%/22%)

Query:  55 PDAGYSPLKRPIQEYIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGC 114
           P   Y PL          G++ LDKPA  SS+  +   +R+LR EK GH+G+LDP  TG 
Sbjct:   3 PRIAYRPLH---------GILLLDKPAGLSSNNALQAARRLLRAEKGGHTGSLDPLATGL  53

Query: 115 LIVCIERATRLVKSQQSAGKEYVAVLRL-----------HGMR----PELDEATVRRAIE 159
           L +C   AT++      + K Y A + L             +R    P++ EA ++ A+ 
Sbjct:  54 LPLCFGEATKIAGLLLGSAKAYDAEIVLGVTTDTDDADGEPLRERAVPDVSEADLQVALA 113

Query: 160 TLTGPLYQRPPLISAVK--------------------RQLRIRTIYESKLLEYDPKRRLV 199
              G + Q+ P+ SA+K                    R++ ++ I   ++L Y   R  +
Sbjct: 114 AFIGRIQQQAPIYSALKQGGEPLYAKARRGEVIDAPVREVEVQAI---EVLGYSAPR--L 168

Query: 200 LFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRV 234
              V+C +GTYIR+L   LG +LG G H+  LRR+
Sbjct: 169 TLRVTCGSGTYIRSLARDLGEVLGCGAHIASLRRL 203

ref|ZP_00062803.1| COG0130: Pseudouridine synthase [Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293]
(302 aa)

Score: 87 bits (214), Expect: 8.43808e-16
Length: 201, Idn/Pos/Gap = 62/101/38 (30%/50%/18%)

Query:  70 IRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQ 129
           I  G++ ++K    +S +VV+ ++RI+  +K GH+GTLDP V G L+V + +AT+L+   
Sbjct:   6 IVDGLLVINKSRGMTSFDVVSRVRRIIGQKKVGHAGTLDPNVDGVLVVALGKATKLIDEL  65

Query: 130 QSAGKEYVAVLRLHGMRPE-----------LDEAT------VRRAIETLTGPLYQRPPLI 172
           Q+  K Y+  + L G   E           LD  T      + +AI+ L G + QRPP+ 
Sbjct:  66 QTRPKSYIGEITL-GFSTETEDLDGEIVDQLDIVTPFSDQKIDQAIQQLNGEITQRPPMY 124

Query: 173 SAVK-----------------RQLRIRTIYESKL---LEYDPKRRLVLFWVSCEAGTYIR 212
           SAVK                 R +R   I++ K    +++   +++  F  +   GTYIR
Sbjct: 125 SAVKVNGKRLYEYARNGETVERPVRKAVIHDFKRTSGIKFIEGKQVFKFEATVSKGTYIR 184

Query: 213 TLCVHLGLLLGVGGHMQELRR 233
           TL V  G ++G+   M +L R
Sbjct: 185 TLAVDAGKIIGIPATMTQLTR 205

ref|NP_798833.1| tRNA pseudouridine 55 synthase [Vibrio parahaemolyticus RIMD 2210633]
dbj|BAC60717.1| tRNA pseudouridine 55 synthase [Vibrio parahaemolyticus RIMD 2210633]
sp|Q87M04|TRUB_VIBPA tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(314 aa)

Score: 87 bits (214), Expect: 8.79755e-16
Length: 241, Idn/Pos/Gap = 73/108/39 (30%/44%/16%)

Query:  64 RPIQEYIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERAT 123
           RPI     +GVI LDKP   SS++ +  +KRI   EK GH+G LDP  TG L +C+  AT
Sbjct:   8 RPI-----NGVILLDKPTGISSNDALQKVKRIYFAEKAGHTGALDPLATGMLPICLGEAT  62

Query: 124 RLVKSQQSAGKEYVAVLRLHGMRPELDEA---------------TVRRAIETLTGPLYQR 168
           +  +    + K Y  + +L G R    ++                +   IE   G   Q 
Sbjct:  63 KFSQFLLDSDKRYRVIAKL-GERTNTSDSDGEVVETRPVDVTLEKLEACIEKFRGESDQV 121

Query: 169 PPLISAVKRQLRIRTIYESKLLEYDPKRRLVLFW---------------VSCEAGTYIRT 213
           P + SA+K Q +    Y  K +E   + R +  +               V C  GTYIRT
Sbjct: 122 PSMFSALKYQGKPLYEYARKGIEVPRESRKITVYEIILHRFEGDEVEMEVHCSKGTYIRT 181

Query: 214 LCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKP 273
           +   LG +LG G H+  LRR     +  Y+ MVT+  +   + L    ++E   R ++ P
Sbjct: 182 IVDDLGEMLGCGAHVTMLRRTAVAKYP-YEKMVTLEQL--NELLEQAHREEIAPRELLDP 238

Query: 274 L 274
           L
Sbjct: 239 L 239

ref|NP_660705.1| tRNA pseudouridine synthase B [Buchnera aphidicola str. Sg (Schizaphis graminum)]
gb|AAM67916.1| tRNA pseudouridine synthase b [Buchnera aphidicola str. Sg (Schizaphis graminum)]
sp|Q8K9H3|TRUB_BUCAP tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(312 aa)

Score: 87 bits (214), Expect: 9.09612e-16
Length: 208, Idn/Pos/Gap = 67/97/34 (32%/46%/16%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           +G + LDKP   +S+ V+  +K I + +K G+ GTLDP  TG L +C   AT+      +
Sbjct:  10 NGFLLLDKPKGMTSNNVLQKVKIIFKAKKAGYIGTLDPLATGILPICFGEATKFSNYLNA  69

Query: 132 AGKEYVAVLRL--HGMRPELDEATVRR------------AIETLTGPLYQRPPLISA--- 174
           + K Y  + RL       + D   VR+            A++ LTG + Q P + SA   
Sbjct:  70 SDKHYNVIARLGEKTSTSDSDGIIVRKRPILFTPIQLSLALKALTGSVNQIPSMYSAVKY 129

Query: 175 --------------VKRQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGL 220
                         VKR +R   IY+  L+  D K   +   V C  GTYIRTL   LG 
Sbjct: 130 KGIPLYKYARQGINVKRNIRCVFIYKIDLV--DQKDNWIELNVHCSKGTYIRTLIEDLGE 187

Query: 221 LLGVGGHMQELRRVRSGVHSEYDGMVTM 248
            L  G H+  LRR++ G+ S Y  +V +
Sbjct: 188 KLFCGAHVIRLRRLKIGLLS-YSKLVKL 214

ref|YP_088633.1| TruB protein [Mannheimia succiniciproducens MBEL55E]
gb|AAU38048.1| TruB protein [Mannheimia succiniciproducens MBEL55E]
sp|Q65SL2|TRUB_MANSM tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(305 aa)

Score: 87 bits (214), Expect: 1.05702e-15
Length: 262, Idn/Pos/Gap = 75/120/44 (28%/45%/16%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           GV  LDKP   SS++++  +KRI +  K GH+G LDP  TG L +C+  AT+  +    A
Sbjct:  13 GVFLLDKPQGMSSNDILQKVKRIYQANKAGHTGALDPLATGMLPICLGEATKFSQFLLDA  72

Query: 133 GKEYVAVLRLHGMRPELDEA------------TVRRAIETLT---GPLYQRPPLISAVK- 176
            K Y  + +L G R +  +A            T ++ +++L    G + Q P + SA+K 
Sbjct:  73 DKRYQVIAKL-GERTDTSDAEGQVVETRSVNVTEQKILDSLPHFRGDIMQVPTMFSALKH 131

Query: 177 ----------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGL 220
                           R+ R  +I+E   + Y+     +   V C  GTYIRTL   LG 
Sbjct: 132 KGKPLYEYARAGIVVEREARPISIFELNFISYEAP--YLTLEVHCSKGTYIRTLVDDLGE 189

Query: 221 LLGVGGHMQELRRVRSGVHSEY--DGMVTMHDVLDAQWLFDTTKDESYLRRVIKPLESLL 278
            LG G H+  LRR      S+Y  D M+T   +      F   +D + L   + P++S +
Sbjct: 190 YLGCGAHVSMLRRTAV---SDYPADKMLTWEQLQQ----FAQDEDLAALDARLLPVDSAV 242

Query: 279 VHHKRIVIKDSCVNAVCYGAKL 300
                + + +    AV +G ++
Sbjct: 243 SKLPVLSLSEEQTKAVGFGQRV 264

gb|AAD50463.1| TruB [Flavobacterium johnsoniae]
sp|Q9RB36|TRUB_CYTJO tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(229 aa)

Score: 86 bits (213), Expect: 1.27e-15
Length: 220, Idn/Pos/Gap = 62/95/52 (28%/43%/23%)

Query:  67 QEYIRSGVINLDKPANPSSHEVVAWIKRIL-------RVEKTGHSGTLDPQVTGCLIVCI 119
           +EY+   V+ +DKP   SS + V  +K +L       +  K GH+GTLDP  TG L++C 
Sbjct:   4 EEYLEGQVLLIDKPLKWSSFQAVNKLKYLLINKVGLPKKFKIGHAGTLDPLATGLLLICT  63

Query: 120 ERATRLVKSQQSAGKEYVAVLRLHGMRPELD---------------EATVRRAIETLTGP 164
            + T+ +   Q   KEY     +    P  D               E  +   ++   G 
Sbjct:  64 GKFTKKISELQGQAKEYTGTFYIGATTPSYDLETEIDQTFPTEHINEVLIHETVKQFLGE 123

Query: 165 LYQRPPLISAVKR-----------------QLRIRTIYESKLLEYDPKRRLVL----FWV 203
           + Q+PP+ SA+K+                 + R  TI+E ++       R+ L    F V
Sbjct: 124 IDQKPPIFSAIKKDGVRLYEHARAGESIEIESRKTTIHEFEI------TRIALPEIDFRV 177

Query: 204 SCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYD 243
            C  GTYIR+L    G  +  G H+  LRR + G   +YD
Sbjct: 178 VCSKGTYIRSLAYDFGKAMNSGSHLTVLRRTKIG---DYD 214

ref|YP_048828.1| tRNA pseudouridine synthase B [Erwinia carotovora subsp. atroseptica SCRI1043]
emb|CAG73629.1| tRNA pseudouridine synthase B [Erwinia carotovora subsp. atroseptica SCRI1043]
sp|Q6D9A3|TRUB_ERWCT tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(314 aa)

Score: 86 bits (213), Expect: 1.3131e-15
Length: 211, Idn/Pos/Gap = 63/100/36 (29%/47%/17%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           GV+ LDKP   SS++V+  +KRI    + GH+G LDP  TG L +C+  AT+  +    +
Sbjct:  13 GVLLLDKPQGVSSNDVLQKVKRIFNANRAGHTGALDPLATGMLPICLGEATKFSQYLLDS  72

Query: 133 GKEYVAVLRLHGMRPELDEA---------------TVRRAIETLTGPLYQRPPLISAVK- 176
            K Y  + RL G R +  +A                +  A+E+  G   Q P + SA+K 
Sbjct:  73 DKRYRVIARL-GQRTDTSDADGNVIEERAIGFSATDLELALESFRGTTQQVPSMYSALKY 131

Query: 177 ----------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGL 220
                           R+ R  T+YE + + ++     +   + C  GTYIRT+   LG 
Sbjct: 132 QGRKLYEYARQGLTVPREAREITVYELQFIRWEGDE--LELEIHCSKGTYIRTIIDDLGE 189

Query: 221 LLGVGGHMQELRRVRSGVHSEYDGMVTMHDV 251
            LG G H+  LRR++  ++   + MVT+  +
Sbjct: 190 QLGCGAHVIYLRRLQVAIYPT-ERMVTLEQL 219

ref|ZP_00109397.1| COG0130: Pseudouridine synthase [Nostoc punctiforme PCC 73102]
(294 aa)

Score: 86 bits (212), Expect: 1.46354e-15
Length: 267, Idn/Pos/Gap = 77/130/52 (28%/48%/19%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           G +NL+KP + +SH+ VA ++++LR+++ GH+GTLDP  TG L + + +ATRL++     
Sbjct:   5 GFLNLNKPFDWTSHDCVARVRKLLRLKRVGHAGTLDPAATGVLPIALGKATRLLQ-YLPE  63

Query: 133 GKEYVAVLRLHGMRPELDE----------------ATVRRAIETLTGPLYQRPPLISAVK 176
            K Y A +RL G+R   D+                A V+ A+    G + Q PP+ SA+ 
Sbjct:  64 NKAYKATIRL-GVRTTTDDLQGEIITSQPCTGLSLAEVKTALAQFEGKIEQIPPIYSAI- 121

Query: 177 RQLRIRTIY----ESKLLEYDPKRRLVLF------W-----------VSCEAGTYIRTLC 215
            Q+  + +Y    + K +E  P R + +F      W           ++C +GTYIR + 
Sbjct: 122 -QVDGKRLYDLARQGKTVEV-PVRTVEVFRIDILDWREGDFPELDVAIACGSGTYIRAIA 179

Query: 216 VHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPLE 275
             LG  L  GG +  L R  S   +  D + T+ D L+AQ        E+   +++ P +
Sbjct: 180 RDLGASLETGGTLAALIRTESSGFNLTDSL-TLTD-LEAQL-------EAGTFQLVFP-D 229

Query: 276 SLLVHHKRIVIKDSCVNAVCYGAKLML 302
           + L H   + +  +     C G ++ L
Sbjct: 230 AALQHLSSVTLPATSAQKWCQGQRISL 256

gb|AAM37532.1| tRNA pseudouridine synthase B [Xanthomonas axonopodis pv. citri str. 306]
ref|NP_642996.1| tRNA pseudouridine synthase B [Xanthomonas axonopodis pv. citri str. 306]
sp|Q8PJ57|TRUB_XANAC tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(308 aa)

Score: 86 bits (212), Expect: 1.55156e-15
Length: 192, Idn/Pos/Gap = 63/97/30 (32%/50%/15%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           G++ LDKP+  SS+  +   +R+LR EK GH+G+LDP  TG L +C   AT++      +
Sbjct:  12 GILLLDKPSGLSSNNALQAARRLLRAEKGGHTGSLDPLATGLLPLCFGEATKIAGLLLGS  71

Query: 133 GKEYVAVLRL-----------HGMR----PELDEATVRRAIETLTGPLYQRPPLISAVKR 177
            K Y A + L             +R    P+L EA ++ A+    G + Q+ P+ SA+K+
Sbjct:  72 AKAYDAEIVLGVTTDTDDADGESLRERAVPDLSEADLQAALAPFIGRIQQQAPIYSALKQ 131

Query: 178 -------QLRIRTIYESKLLEYDPKRRLVLFW--------VSCEAGTYIRTLCVHLGLLL 222
                  + R     E+ + E D +   VL +        V+C +GTYIR+L   LG  L
Sbjct: 132 GGEPLYAKARRGERIEAPVREVDVQAIEVLGYGAPRLRLRVTCGSGTYIRSLARDLGEAL 191

Query: 223 GVGGHMQELRRV 234
           G G H+  LRR+
Sbjct: 192 GCGAHIASLRRL 203

ref|ZP_00179463.2| COG0130: Pseudouridine synthase [Crocosphaera watsonii WH 8501]
(297 aa)

Score: 86 bits (212), Expect: 1.71496e-15
Length: 198, Idn/Pos/Gap = 66/96/36 (33%/48%/18%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           G I L+KP+  +SH+ VA ++R+L ++K GH GTLDP  TG L + + +ATRL+      
Sbjct:   3 GFIPLNKPSGFTSHDCVAKVRRLLNIKKVGHGGTLDPAATGVLPIAVGKATRLLPFLPE-  61

Query: 133 GKEYVAVLRLHGMRPELD----EATVRRAIETLT------------GPLYQRPPLISAVK 176
            K Y A +R  GM+   D    E   R++   LT            G + Q PP+ SA++
Sbjct:  62 NKAYRATIRF-GMQTTTDDLQGEVIQRQSASHLTIEEIKPLFNDFLGEIEQIPPIYSAIQ 120

Query: 177 RQ-LRIRTIYESKLLEYDPKRRL------VLFW-----------VSCEAGTYIRTLCVHL 218
           R   R+  +     +   P RR+      VL W           + C  GTYIR +   +
Sbjct: 121 RDGKRLYELARKGEIVDIPVRRVKVDKIEVLDWYVEEFCELVVNIECGPGTYIRAIARDI 180

Query: 219 GLLLGVGGHMQELRRVRS 236
           G  LGVGG +  L R +S
Sbjct: 181 GDKLGVGGTLAALTRTKS 198

ref|NP_806880.1| tRNA pseudouridine 55 synthase [Salmonella enterica subsp. enterica serovar Typhi Ty2]
ref|NP_457666.1| tRNA pseudouridine 55 synthase (psi55 synthase) (p35 protein) [Salmonella enterica subsp. enterica serovar Typhi str. CT18]
emb|CAD07804.1| tRNA pseudouridine 55 synthase (psi55 synthase) (p35 protein) [Salmonella enterica subsp. enterica serovar Typhi]
gb|AAO70740.1| tRNA pseudouridine 55 synthase [Salmonella enterica subsp. enterica serovar Typhi Ty2]
sp|Q8Z3H9|TRUB_SALTI tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
pir||AF0901 tRNA pseudouridine 55 synthase (psi55 synthase) (p35 protein) [imported] - Salmonella enterica subsp. enterica serovar Typhi (strain CT18)
(314 aa)

Score: 85 bits (211), Expect: 2.29658e-15
Length: 206, Idn/Pos/Gap = 66/96/32 (32%/46%/15%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           GV+ LDKP   SS++V+  +KRI    + GH+G LDP  TG L +C+  AT+  +    +
Sbjct:  13 GVLLLDKPQGMSSNDVLQKVKRIYNANRAGHTGALDPLATGMLPICLGEATKFSQYLLDS  72

Query: 133 GKEYVAVLRLHGMRPELDEA---------------TVRRAIETLTGPLYQRPPLISAVKR 177
            K Y  + RL G R +  +A                +  A+ET  G + Q P + SA+K 
Sbjct:  73 DKRYRVIARL-GQRTDTSDADGQIVQERPVTFSAEQLASALETFRGDIEQIPSMYSALKY 131

Query: 178 QLRIRTIYESKLLEYDPKRRLVLFW---------------VSCEAGTYIRTLCVHLGLLL 222
           Q R    Y  + +E   + R +  +               V C  GTYIRT+   LG  L
Sbjct: 132 QGRKLYEYARQGIEVPREARPITVYELLFIRHEGNELELEVHCSKGTYIRTIIDDLGEKL 191

Query: 223 GVGGHMQELRRVRSGVHSEYDGMVTM 248
           G G H+  LRR+    +   D MVT+
Sbjct: 192 GCGAHVTYLRRLTVSKYP-VDRMVTL 216

sp|Q9PKU2|TRUB_CHLMU tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(241 aa)

Score: 85 bits (211), Expect: 2.31582e-15
Length: 196, Idn/Pos/Gap = 65/97/33 (33%/49%/16%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERA-TRLVKSQQS 131
           GV+ +DKP   +S  ++  + R++ V+K GH+GTLDP  TG +++ I R  TRL      
Sbjct:  10 GVLLVDKPQGRTSFSLIRSLVRLIGVKKIGHAGTLDPFATGVMVMLIGRKFTRLSDIMLF  69

Query: 132 AGKEYVAVLRLHGMRPELD-----------EATVRRAIETLT---GPLYQRPPLISAVKR 177
             KEY AV  L       D             T+   +E  +   G + Q PP+ SA K 
Sbjct:  70 EDKEYSAVAHLGTTTDTYDCDGKIVGRSKKVPTMEEVLECTSYFQGEIQQVPPMFSAKKV 129

Query: 178 Q-----------LRIRTIYES-----KLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLL 221
           Q           L I   + +     +L++Y+  R  + F V C  GTYIR++   LG +
Sbjct: 130 QGKKLYEYARQGLSIERSFATVRVDLRLIKYEYPR--LHFVVKCSKGTYIRSIAHELGNM 187

Query: 222 LGVGGHMQELRRVRSG 237
           LG G +++ELRR+RSG
Sbjct: 188 LGCGAYLEELRRLRSG 203

ref|ZP_00337170.1| COG0130: Pseudouridine synthase [Silicibacter sp. TM1040]
(302 aa)

Score: 85 bits (211), Expect: 2.39441e-15
Length: 292, Idn/Pos/Gap = 83/129/48 (28%/44%/16%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           SG + +DKPA  +S  VV  ++     +K GH+GTLDP+ TG L V +  AT+ V     
Sbjct:  11 SGWLVVDKPAGLTSTAVVNKVRWAFDAKKAGHAGTLDPEATGVLAVALGEATKTVPFITD  70

Query: 132 AGKEYV----------------AVLRLHGMRPELDEATVRRAIETLTGPLYQRPPLISAV 175
           A K Y                  V+     RP  D+  ++ A+    G + Q PP  SAV
Sbjct:  71 AMKAYTFTVTLGAATNTDDAEGEVIATSAERPTDDD--IKEALLGFIGEIQQVPPKFSAV 128

Query: 176 K---------------RQLRIRTIYESKLLEYD-PKRRLVLFWVSCEAGTYIRTLCVHLG 219
           K                +L  R ++  +L+  D P    V+  ++C  G Y+R++   LG
Sbjct: 129 KIDGQRAYKLARDGEEVELSARPLWVEELVMLDRPDADHVVLEMTCGKGGYVRSIARDLG 188

Query: 220 LLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPLESLLV 279
             LG  GH++ELRR+ SG     DG VT+  +       D       + + ++PLE  L 
Sbjct: 189 EKLGCLGHVRELRRIWSGPFDAEDG-VTLEQI-------DALAKSPEIDQFLRPLEEGLA 240

Query: 280 HHKRIVIKDSCVNAVCYGAKLMLPGVLRYENDIECGEEVVIMTTKGEAVALA 331
               +         +  G     PG++   +D+E GEE    + +G+AVA+ 
Sbjct: 241 DLPELKCTPQGATRLRNGN----PGMV-IASDVEYGEE-AWASLEGKAVAVG 286

ref|ZP_00091230.1| COG0130: Pseudouridine synthase [Azotobacter vinelandii]
(305 aa)

Score: 85 bits (210), Expect: 2.64657e-15
Length: 196, Idn/Pos/Gap = 61/92/33 (31%/46%/16%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           G++ LDKP   +S+  +  ++ +L  EK GH+G+LDP  TG L +C   AT+  +    A
Sbjct:  13 GILVLDKPHGLTSNAALQKVRWLLNAEKAGHTGSLDPLATGVLPLCFGEATKFSQYLLDA  72

Query: 133 GKEYVAVLRLHGMRPELD---EATVRRAIE-----------TLTGPLYQRPPLISAVK-- 176
            K Y  ++ L       D   E   RRA++              G + Q PP+ SA+K  
Sbjct:  73 DKGYETLMHLGVTTTTGDAEGEVLERRAVQLGRDALESVLADFRGEISQVPPMYSALKRD 132

Query: 177 ---------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLL 221
                          R+ R  TI   +LL ++P        V+C  GTY+R+L   +G  
Sbjct: 133 GQPLYKLARAGEVVEREARSVTIARLELLAFEPP--FARLAVACSKGTYVRSLVEDIGRA 190

Query: 222 LGVGGHMQELRRVRSG 237
           LG G H+ ELRR ++G
Sbjct: 191 LGFGAHVAELRRTQAG 206

ref|NP_789044.1| tRNA pseudouridine synthase B [Tropheryma whipplei TW08/27]
emb|CAD66781.1| tRNA pseudouridine synthase B [Tropheryma whipplei TW08/27]
sp|Q820Z5|TRUB_TROW8 tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(383 aa)

Score: 85 bits (210), Expect: 2.78243e-15
Length: 197, Idn/Pos/Gap = 64/93/33 (32%/47%/16%)

Query:  74 VINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAG 133
           V+ +DK +  +SH  VA I+ +  V+K GH GTLDP   G LI+    ATRL++   +  
Sbjct:  19 VLLVDKISGITSHTAVAKIRHLTGVKKIGHCGTLDPAACGLLIMGCGTATRLIRYMSNLD  78

Query: 134 KEYVAVLRLHGM---------------RPELDEATVR---RAIETLTGPLYQRPPLISAV 175
           K Y+A + L                  +P LD+ T+    RA E L+G + Q P   SA+
Sbjct:  79 KRYIATITLGTQTTTDDSEGEIIYSAPKPSLDKITLESIGRAAEKLSGTIKQIPSAYSAI 138

Query: 176 K----------RQ-----LRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGL 220
           K          RQ     L  R +        D +   V   ++C +GTY+R L   +G 
Sbjct: 139 KVSGNRAYNLARQGIIPKLNAREVRVHWKFLGDFENNQVHVQITCSSGTYVRALARDMGK 198

Query: 221 LLGVGGHMQELRRVRSG 237
            LGVGGH+  L+R+  G
Sbjct: 199 FLGVGGHLSYLKRLSIG 215

ref|NP_623008.1| Pseudouridine synthase [Thermoanaerobacter tengcongensis MB4]
gb|AAM24612.1| Pseudouridine synthase [Thermoanaerobacter tengcongensis MB4]
sp|Q8RA40|TRUB_THETN tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(285 aa)

Score: 85 bits (210), Expect: 2.85296e-15
Length: 197, Idn/Pos/Gap = 64/93/33 (32%/47%/16%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           GV+N+ KP   +SH+VV +I++I  ++K GH+GTLDP   G L VC+ RAT+        
Sbjct:   5 GVLNVLKPPGMTSHDVVDFIRKIYGIKKVGHTGTLDPDAAGVLPVCMGRATKFTSYLMEH  64

Query: 133 GKEYVAVLRLHGMRPELDEA------------TVRRAIETLT---GPLYQRPPLISAVK- 176
            K Y   +        LD++            T+ +  E L+   G + Q PP+ SA K 
Sbjct:  65 DKRYRFEITFGFSTDTLDKSGKIVESGPVPLFTLEKLQEVLSQFKGEIQQIPPIYSAKKV 124

Query: 177 ------------RQLRIR----TIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGL 220
                        ++ I     T+YE +L++YD    L+L  V C  GTY+R L   +  
Sbjct: 125 KGKKLYEYARKGEEVEIPPIKVTVYELELIKYDAPHHLLLD-VKCSKGTYVRALVRDICK 183

Query: 221 LLGVGGHMQELRRVRSG 237
            L V GHM  L R   G
Sbjct: 184 KLEVPGHMSFLIRTEVG 200

ref|YP_152291.1| tRNA pseudouridine 55 synthase (psi55 synthase) (p35 protein) [Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150]
gb|AAV78979.1| tRNA pseudouridine 55 synthase (psi55 synthase) (p35 protein) [Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150]
sp|Q5PLB2|TRUB_SALPA tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(314 aa)

Score: 85 bits (210), Expect: 2.9745e-15
Length: 238, Idn/Pos/Gap = 72/109/38 (30%/45%/15%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           GV+ LDKP   SS++V+  +KRI    + GH+G LDP  TG L +C+  AT+  +    +
Sbjct:  13 GVLLLDKPQGMSSNDVLQKVKRIYNANRAGHTGALDPLATGMLPICLGEATKFSQYLLDS  72

Query: 133 GKEYVAVLRLHGMRPELDEA---------------TVRRAIETLTGPLYQRPPLISAVK- 176
            K Y  + RL G R +  +A                +  A+ET  G + Q P + SA+K 
Sbjct:  73 DKRYRVIARL-GQRTDTSDADGQIVQERPVTFSAEQLASALETFRGDIEQIPSMYSALKY 131

Query: 177 ----------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGL 220
                           R+ R  T+YE   + ++     +   V C  GTYIRT+   LG 
Sbjct: 132 QGKKLYEYARQGIEVPREARPITVYELLFIRHEGNE--LELEVHCSKGTYIRTIIDDLGE 189

Query: 221 LLGVGGHMQELRRVRSGVHSEYDGMVTMHDV--LDAQWLFDTTKDESYLRRVIKPLES 276
            LG G H+  LRR+    +   D MVT+  +  L AQ          +L  ++ P++S
Sbjct: 190 KLGCGAHVTYLRRLTVSKYP-VDRMVTLEHLQTLVAQAEQQGVPAAQWLDPLLMPMDS 246

ref|NP_661147.1| tRNA pseudouridine synthase B [Chlorobium tepidum TLS]
gb|AAM71489.1| tRNA pseudouridine synthase B [Chlorobium tepidum TLS]
sp|Q8KFS9|TRUB_CHLTE tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(240 aa)

Score: 85 bits (210), Expect: 2.99942e-15
Length: 206, Idn/Pos/Gap = 67/96/39 (32%/46%/18%)

Query:  77 LDKPANPSSHEVVAWI----KRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           +DKP + +S +VVA I    KR     K GH GTLDP+ TG LI+   R T+ + S +  
Sbjct:  19 VDKPLDWTSFDVVAKIRGAYKRNGAKRKVGHCGTLDPKATGLLILATGRKTKTISSLELL  78

Query: 133 GKEYVAVLRL-------------HGMR--PELDEATVRRAIETLTGPLYQRPPLISAVKR 177
            K Y   +RL             + +R  P LDE  +R A  ++ G   Q+PP+ SAV  
Sbjct:  79 DKAYEGTIRLGAKTVSHDTESEEYDLRDVPSLDERAIREAATSMIGERMQQPPMHSAVWH 138

Query: 178 QLRIRTIYESKLLEYDPKRR------------------LVLFWVSCEAGTYIRTLCVHLG 219
             +   +YE     ++ K R                   V F++    G YIR +   LG
Sbjct: 139 NGK--RLYELARQGHEVKERKARQIEIHQFEITGIELPYVHFYIRVSKGAYIRVIAHELG 196

Query: 220 LLLGVGGHMQELRRVRSGVHSEYDGM 245
            LLGVGG+++ L+RV  G +   D M
Sbjct: 197 ELLGVGGYLKSLKRVAIGQYQLSDAM 222

gb|AAN87441.1| tRNA pseudouridine synthase B [Heliobacillus mobilis]
sp|Q8GB99|TRUB_HELMO tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(307 aa)

Score: 85 bits (210), Expect: 3.1534e-15
Length: 211, Idn/Pos/Gap = 68/100/39 (32%/47%/18%)

Query:  60 SPLKRPIQEYIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCI 119
           +PLK P++     G +N+ KP   +SH+VVA  +RILR ++ GH GTLDP   G L + +
Sbjct:   2 NPLKSPLE-----GFLNILKPPGMTSHDVVAKARRILREKRIGHMGTLDPDAAGVLPIAL  56

Query: 120 ERATRLVKSQQSAGKEYVAVLRLHGMR---------------PELDEATVRRAIETLTGP 164
            +ATRL++  +   K Y A L L  +                P+L        ++   G 
Sbjct:  57 GQATRLIELVR-GDKSYRAQLLLGRITDSQDVSGRIVEEHPIPQLTRQAWEELLKEFQGL 115

Query: 165 LYQRPPLISAVKRQLRIRTIYESKLLEYD-PKRRL-----------------VLFWVSCE 206
           + Q PP++SAV    +    Y  + +E + P R++                 ++  V C 
Sbjct: 116 MEQIPPMVSAVSVGGKRLYEYARQGIEVERPSRKINIDRIDIVQYHEHAPGELILDVDCS 175

Query: 207 AGTYIRTLCVHLGLLLGVGGHMQELRRVRSG 237
            GTYIRTLC  +G  LG G  M  L R RSG
Sbjct: 176 GGTYIRTLCHDIGQRLGCGAIMGWLIRRRSG 206

ref|NP_240193.1| tRNA pseudouridine 55 synthase [Buchnera aphidicola str. APS (Acyrthosiphon pisum)]
sp|P57456|TRUB_BUCAI tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
dbj|BAB13079.1| tRNA pseudouridine 55 synthase [Buchnera aphidicola str. APS (Acyrthosiphon pisum)]
pir||G84973 tRNA pseudouridine 55 synthase [imported] - Buchnera sp.  (strain APS)
(312 aa)

Score: 85 bits (209), Expect: 3.26042e-15
Length: 211, Idn/Pos/Gap = 61/100/31 (28%/47%/14%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           G++ LDKP   SS+  +  +K +   +K G+ GTLDP  TG L +C    ++       +
Sbjct:  11 GLLLLDKPQGISSNNALQKVKMLFSAKKAGYIGTLDPLATGMLPICFGECSKFSHYLMES  70

Query: 133 GKEYVAVLRL---------HGM----RPEL-DEATVRRAIETLTGPLYQRPPLISAVKR- 177
            K+Y  + +L          G+    RP L +   ++ A++ LTG + Q PP+ SA+K  
Sbjct:  71 NKKYHVIAKLGEKTSTSDSDGIIIKKRPILINSFKIKSALKELTGLIEQIPPMYSAIKHN 130

Query: 178 --------------QLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLLLG 223
                         +  IR +    +     ++ L+ F + C  GTY+RTL   LG  LG
Sbjct: 131 GVPLYKYARQGLNIKRSIRKVLIHDISSIHQEKNLIEFKIFCSKGTYVRTLVEDLGEKLG 190

Query: 224 VGGHMQELRRVR--SGVHSEYDGMVTMHDVL 252
            G H+  LRR+   S +HS+   +  +H +L
Sbjct: 191 CGAHVIFLRRLEMASYLHSQLVTISYLHKLL 221

ref|NP_443002.1| tRNA pseudouridine 55 synthase [Synechocystis sp. PCC 6803]
sp|P74696|TRUB_SYNY3 tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
dbj|BAA18814.1| tRNA pseudouridine 55 synthase [Synechocystis sp. PCC 6803]
(296 aa)

Score: 85 bits (209), Expect: 3.34307e-15
Length: 320, Idn/Pos/Gap = 94/148/64 (29%/46%/20%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           G +NL KP + +SH+ VA ++R+LR ++ GH GTLDP   G L + +  ATRL+     A
Sbjct:   3 GFLNLHKPLHLTSHDCVAKVRRLLRQKRVGHGGTLDPLAEGVLPLAVGSATRLLPYLPGA  62

Query: 133 GKEYVAVLRLHGMRPELDE----------------ATVRRAIETLTGPLYQRPPLISAVK 176
            K+Y A++R  G+R + D+                A V + + T  G + Q PP  SA+ 
Sbjct:  63 -KQYQALIRF-GVRTDSDDLAGEVLESKNVSYLTLAAVEQILPTFLGEIEQIPPQYSAI- 119

Query: 177 RQLRIRTIYE---SKLLEYDPKRRL------VLFW-----------VSCEAGTYIRTLCV 216
            Q+  + +YE   + + +  P R +      +L W           V+C  GTYIR L  
Sbjct: 120 -QVNGKRLYELARAGIPQAVPSRMVTINDLKILGWRSGNQPELDLQVTCGEGTYIRALAR 178

Query: 217 HLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPLES 276
            LG  LG G  +  L R +SG      GM  + + +    L     +E ++  +  P + 
Sbjct: 179 DLGDRLGTGATLAGLVRQQSG------GM-ALDNSVGLTALEKIVAEEEHIPLI--PPQE 229

Query: 277 LLVHHKRIVIKDSCVNAVCYGAKLMLPGVLRYENDIECGEEVVIMTTK-GEAVALAIAHM 335
            L H   + +         +G +L+LP       D+  G  VV++T++ G    L +A +
Sbjct: 230 ALSHLPTVQLNSELEKRWFHGQRLLLP-------DLPVG--VVLITSELGPVKCLGVA-L 279

Query: 336 STSEIASCDHGVVARIKRVV 355
            T E    DHG V R K V+
Sbjct: 280 VTPE----DHGTVLRPKVVL 295

ref|YP_218212.1| tRNA pseudouridine 5S synthase [Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67]
gb|AAX67131.1| tRNA pseudouridine 5S synthase [Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67]
gb|AAL22156.1| tRNA pseudouridine 5S synthase [Salmonella typhimurium LT2]
sp|Q8ZLT2|TRUB_SALTY tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
ref|NP_462197.1| tRNA pseudouridine 5S synthase [Salmonella typhimurium LT2]
(314 aa)

Score: 85 bits (209), Expect: 3.60377e-15
Length: 208, Idn/Pos/Gap = 66/97/36 (31%/46%/17%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           GV+ LDKP   SS++V+  +KRI    + GH+G LDP  TG L +C+  AT+  +    +
Sbjct:  13 GVLLLDKPQGMSSNDVLQKVKRIYNANRAGHTGALDPLATGMLPICLGEATKFSQYLLDS  72

Query: 133 GKEYVAVLRLHGMRPELDEA---------------TVRRAIETLTGPLYQRPPLISAVK- 176
            K Y  + RL G R +  +A                +  A+ET  G + Q P + SA+K 
Sbjct:  73 DKRYRVIARL-GQRTDTSDADGQIVQERPVTFSAEQLASALETFRGDIEQIPSMYSALKY 131

Query: 177 ----------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGL 220
                           R+ R  T+YE   + ++     +   V C  GTYIRT+   LG 
Sbjct: 132 QGKKLYEYARQGIEVPREARPITVYELLFIRHEGNE--LELEVHCSKGTYIRTIIDDLGE 189

Query: 221 LLGVGGHMQELRRVRSGVHSEYDGMVTM 248
            LG G H+  LRR+    +   D MVT+
Sbjct: 190 KLGCGAHVTYLRRLTVSKYP-VDRMVTL 216

gb|AAO44184.1| tRNA pseudouridine synthase B [Tropheryma whipplei str. Twist]
ref|NP_787215.1| tRNA pseudouridine synthase B [Tropheryma whipplei str. Twist]
sp|Q820Y5|TRUB_TROWT tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(377 aa)

Score: 84 bits (208), Expect: 4.90719e-15
Length: 197, Idn/Pos/Gap = 63/93/33 (31%/47%/16%)

Query:  74 VINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAG 133
           V+ +DK +  +SH  VA I+ +  ++K GH GTLDP   G LI+    ATRL++   +  
Sbjct:  19 VLLVDKISGITSHTAVAKIRHLTGIKKIGHCGTLDPAACGLLIMGCGTATRLIRYMSNLD  78

Query: 134 KEYVAVLRLHGM---------------RPELDEATVR---RAIETLTGPLYQRPPLISAV 175
           K Y+A + L                  +P LD+ T+    RA E L+G + Q P   SA+
Sbjct:  79 KRYIATITLGTQTTTDDSEGEIIYSAPKPSLDKITLESIGRAAEKLSGTIKQIPSAYSAI 138

Query: 176 K----------RQ-----LRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGL 220
           K          RQ     L  R +        D +   V   ++C +GTY+R L   +G 
Sbjct: 139 KVSGNRAYNLARQGIIPKLNAREVRVHWKFLGDFENNQVHVQITCSSGTYVRALARDMGK 198

Query: 221 LLGVGGHMQELRRVRSG 237
            LGVGGH+  L+R+  G
Sbjct: 199 FLGVGGHLSYLKRLSIG 215

ref|ZP_00153702.2| COG0130: Pseudouridine synthase [Rickettsia rickettsii]
(345 aa)

Score: 84 bits (207), Expect: 6.04538e-15
Length: 205, Idn/Pos/Gap = 63/94/37 (30%/45%/18%)

Query:  75 INLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAGK 134
           +N+ KP   SS ++V+ +K+IL   K GH+GTLD +  G L   +  AT+L++    A K
Sbjct:   6 LNIYKPRGISSAQLVSIVKKILGKTKIGHAGTLDVEAEGILPFAVGEATKLIRLLIDARK  65

Query: 135 EYVAVLRLHGMR-----------------PELDEATVRRAIETLTGPLYQRPPLISAVKR 177
            Y+  ++  GM+                 P  +EA          G + Q PP  SA+K 
Sbjct:  66 TYIFTVKF-GMQTNSGDCAGKVIATKDCVPSQEEAYA--VCSKFIGSVTQIPPAFSALKV 122

Query: 178 ---------------QLRIR--TIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGL 220
                          +L+ R  TIY+ K L +D K     ++  C  GTYIRTL   L L
Sbjct: 123 NGVRAYKLAREEKKVELKPRNITIYDLKCLNFDEKNATATYYTECSKGTYIRTLAEDLAL 182

Query: 221 LLGVGGHMQELRRVRSGVHSEYDGM 245
            L   G + ELRR + G+  E + +
Sbjct: 183 SLQSLGFVIELRRTQVGIFKEENAI 207

ref|NP_682396.1| tRNA pseudouridine synthase B [Thermosynechococcus elongatus BP-1]
sp|Q8CWM3|TRUB_SYNEL tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
dbj|BAC09158.1| tRNA pseudouridine synthase B [Thermosynechococcus elongatus BP-1]
(287 aa)

Score: 84 bits (207), Expect: 6.738e-15
Length: 199, Idn/Pos/Gap = 66/100/36 (33%/50%/18%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           G +NL+KPA  +SH+ +  ++R LR+++ GH GTLDP  TG L + +  ATRL+    S 
Sbjct:   3 GFLNLNKPAGCTSHDCINELRRRLRLKRIGHGGTLDPMATGVLPIALGAATRLL-PYLSD  61

Query: 133 GKEYVAVLRLHGMRPELDE----------------ATVRRAIETLTGPLYQRPPLISAVK 176
            K Y+  +R  GM    D+                A ++  +    G + Q PP  SA++
Sbjct:  62 RKAYIGTVRF-GMSTTTDDITGEICQEQGASHLTLAAIQEQLPQFIGEIEQLPPAYSAIQ 120

Query: 177 ---RQL--------------RIRTIYESKLLEYDPKRRLVL-FWVSCEAGTYIRTLCVHL 218
              ++L              RI T+Y  ++L + P R   L   ++C +GTYIR L   L
Sbjct: 121 VAGQRLYARARAGEVVSVPPRIVTVYRIEVLHWQPGRYPELTLHITCGSGTYIRALARDL 180

Query: 219 GLLLGVGGHMQELRRVRSG 237
           G  LGVGG +  L+R+ SG
Sbjct: 181 GTALGVGGTLAALQRIESG 199

ref|YP_007758.1| probable tRNA pseudouridine synthase B [Parachlamydia sp. UWE25]
emb|CAF23483.1| probable tRNA pseudouridine synthase B [Parachlamydia sp. UWE25]
sp|Q6MD66|TRUB_PARUW tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(262 aa)

Score: 83 bits (206), Expect: 7.63635e-15
Length: 198, Idn/Pos/Gap = 59/95/37 (29%/47%/18%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERA-TRLVKSQQS 131
           G++ ++KP   +S  +V  +++ L V+K GH+GTLDP  TG +++ + R  TRL      
Sbjct:  42 GILLINKPKGKTSFSLVRDLRKRLGVKKIGHAGTLDPFATGVMVMLVGRNYTRLSDQFLL 101

Query: 132 AGKEYVA----------------VLRLHGMRPELDEATVRRAIETLTGPLYQRPPLISAV 175
           + KEY+A                VL    + P L++  ++ A     G + Q PP+ SA 
Sbjct: 102 SDKEYIAEAYLGVVTDSYDCEGQVLSQSNIIPTLEQ--IKEAFSLFQGKIEQVPPMFSAK 159

Query: 176 KRQLR----------------IRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLG 219
           K+Q +                ++    ++LL Y+     + F + C  GTYIR++   LG
Sbjct: 160 KQQGKKLYELARQGIVVERQPVKISIHTELLSYN--YPYLNFRIECSKGTYIRSIAYDLG 217

Query: 220 LLLGVGGHMQELRRVRSG 237
             LG G H+  L R RSG
Sbjct: 218 TKLGCGAHLSNLTRTRSG 235

ref|ZP_00158664.2| COG0130: Pseudouridine synthase [Anabaena variabilis ATCC 29413]
(293 aa)

Score: 83 bits (206), Expect: 8.58256e-15
Length: 201, Idn/Pos/Gap = 61/101/42 (30%/50%/20%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           G INLDKP   +SH+ VA ++++LR+++ GH+GTLDP  TG L + + +ATRL++   S 
Sbjct:   3 GFINLDKPFGWTSHDCVARLRKMLRLKRVGHAGTLDPAATGVLPIAVGKATRLLQYLPS-  61

Query: 133 GKEYVAVLRLHGMRPELDE----------------ATVRRAIETLTGPLYQRPPLISAVK 176
            K Y A +R  G++   D+                + V+ ++    G + Q PP+ SA+ 
Sbjct:  62 DKAYKATVRF-GVQTTTDDLQGEIISSQPCGGLSLSEVKTSLSQFIGKIEQIPPIYSAI- 119

Query: 177 RQLRIRTIYE----SKLLEYDPKRRLVLF------W-----------VSCEAGTYIRTLC 215
            Q+  + +Y+     + +E  P R + +F      W           ++C +GTYIR + 
Sbjct: 120 -QVEGKRLYDLARKGETIEV-PARTVEVFSIDVLDWREGDFPELDVAIACGSGTYIRAIA 177

Query: 216 VHLGLLLGVGGHMQELRRVRS 236
             LG +   GG +  L R  S
Sbjct: 178 RDLGAIFHTGGTLAALIRTHS 198

ref|NP_965287.1| tRNA pseudouridine synthase B [Lactobacillus johnsonii NCC 533]
gb|AAS09253.1| tRNA pseudouridine synthase B [Lactobacillus johnsonii NCC 533]
sp|Q74IT0|TRUB_LACJO tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(297 aa)

Score: 83 bits (206), Expect: 8.87383e-15
Length: 273, Idn/Pos/Gap = 77/119/56 (28%/43%/20%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           +G++ ++KP   +S + V  +++IL++ K GH+GTLDP+V G L + I +AT+L++    
Sbjct:   3 NGIVVVNKPRGVTSSDCVYKLRKILQIRKIGHAGTLDPEVNGVLPIAIGQATKLIELMHE  62

Query: 132 AGKEYVAVLRLHGM------RPELDEAT--------------VRRAIETLTGPLYQRPPL 171
             K Y+      GM        +LD  T              +   ++ LTG + Q PP+
Sbjct:  63 KPKSYIG----SGMFGKATDSYDLDGTTTAEEKIVTPFTSDEIISGMKKLTGKIDQVPPI 118

Query: 172 ISAVK-----------------RQLRIRTIYESKLL---EYDP--KRRLVLFWVSCEAGT 209
            SAV+                 R  R   IY  +L    EYDP  K     F + C  GT
Sbjct: 119 YSAVRVNGKRLYEYARENIPVERPKRKVNIYSYELTQDPEYDPLEKTESFNFAIRCSKGT 178

Query: 210 YIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRR 269
           Y+R+L   LG  LGV   M  L R  S          +  D+  A  L    K+  Y  +
Sbjct: 179 YVRSLVNDLGEELGVPAVMTSLTRTSS----------SGFDLSQAVDLETIEKEIDYPEK 228

Query: 270 VIKPLESLLVHHKRIVIKDSCVNAVCYGAKLML 302
            ++P++S  V   ++ I       V  GA + L
Sbjct: 229 WLQPIDSFFVDLPQLQISPDQFKRVSNGASIKL 261

ref|NP_975334.1| tRNA pseudouridine synthase B [Mycoplasma mycoides subsp. mycoides SC str. PG1]
emb|CAE76976.1| tRNA pseudouridine synthase B [Mycoplasma mycoides subsp. mycoides SC]
sp|Q6MTR0|TRUB_MYCMS tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(292 aa)

Score: 83 bits (205), Expect: 9.25187e-15
Length: 257, Idn/Pos/Gap = 67/117/45 (26%/45%/17%)

Query:  71 RSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQ 130
           +SG+  L+KP+N S+++++  +K+ L ++K GH GTLD   TG +I  +  AT++     
Sbjct:   3 KSGIFILNKPSNISTYQLINQVKKKLNIKKVGHCGTLDLLATGVVICLVNNATKISDYLL  62

Query: 131 SAGKEYVAVLRLHGMRPELDEA---------------TVRRAIETLTGPLY-QRPPLISA 174
           +A K Y   ++L  +    D                  + + I       Y Q PP+ S+
Sbjct:  63 NANKAYQVKIKLFTLTDSFDAEGNIIQTQTPFNISLDQINKVISKYNNYTYNQYPPIYSS 122

Query: 175 VK-------------RQLRIR----TIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVH 217
           +K             + + I+    TIY++ LL YD K   +   V C  GTYIR+L V 
Sbjct: 123 IKVDGKKLYEYALTNQNVEIKSRKVTIYKTSLLSYDQKNYEIFLDVKCSKGTYIRSLAVD 182

Query: 218 LGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQW-----LFDTTKDESYLRRVIK 272
           +   L   G++  L R  SG     + +    D+ +  W     + D  +   +  +V+K
Sbjct: 183 ICKDLNTIGYVVYLNRTLSGNFKLENAI----DLNNISWDHLISINDAIRTNDF--KVVK 236

Query: 273 PLESL-LVHHKRIVIKD 288
              SL ++  K+I++ D
Sbjct: 237 YQNSLEIIQGKKIILND 253

ref|NP_833530.1| tRNA pseudouridine synthase B [Bacillus cereus ATCC 14579]
gb|AAP10731.1| tRNA pseudouridine synthase B [Bacillus cereus ATCC 14579]
(282 aa)

Score: 83 bits (205), Expect: 1.07512e-14
Length: 180, Idn/Pos/Gap = 59/85/39 (32%/47%/21%)

Query:  96 LRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAGKEYVAVLRLHGMRPELDEAT-- 153
           +R ++ GH+GTLDP VTG L +C+ RAT++ +   S  K Y   + L G     ++A+  
Sbjct:   1 MREKRIGHTGTLDPDVTGVLPICVGRATKIAQFLTSETKTYEGEVTL-GFSTTTEDASGE  59

Query: 154 ---------------VRRAIETLTGPLYQRPPLISAVK-----------------RQLRI 181
                          V + +  LTG + Q PP+ SAVK                 R +R 
Sbjct:  60 VVETKNVDRTITRMEVEKVLAELTGTIEQMPPMFSAVKVNGKKLYEYARAGQEVERPVRT 119

Query: 182 RTIYESKLLE----YDPKRRLVLFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSG 237
            TI+E  LL+    ++ +     F V+C  GTY+RTL V +G  LG   HM  L R  SG
Sbjct: 120 ITIHEFVLLDDREVFEGENISFRFRVTCSKGTYVRTLAVMIGEKLGFPSHMSHLVRTASG 179

ref|NP_778438.1| tRNA pseudouridine synthase B [Xylella fastidiosa Temecula1]
gb|AAO28087.1| tRNA pseudouridine synthase B [Xylella fastidiosa Temecula1]
sp|Q87EV2|TRUB_XYLFT tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(302 aa)

Score: 83 bits (204), Expect: 1.40414e-14
Length: 191, Idn/Pos/Gap = 62/91/30 (32%/47%/15%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           G++ LDKPA  SS+  +   +R+LR +K GH+G+LDP  TG L +C   AT++      +
Sbjct:  13 GILLLDKPAGISSNSALQVARRLLRAKKGGHTGSLDPLATGLLPLCFGEATKIAGLLLDS  72

Query: 133 GKEYVAVLRLHGMR---------------PELDEATVRRAIETLTGPLYQRPPLISAVKR 177
            K Y A + L                   P LD   V   I  L G + QR P+ SA+K+
Sbjct:  73 TKAYDADVLLGTTTTTDDAEGAVLLTRPVPTLDAEMVDALIPQLIGRIRQRAPIYSALKQ 132

Query: 178 -------QLRIRTIYESKLLEYDPKRRLVLFW--------VSCEAGTYIRTLCVHLGLLL 222
                  + R   +  + + E +     +LF         V+C +GTYIR+L   LG +L
Sbjct: 133 GGEPLYAKARRGEVVNAPVREVEVHAIELLFLATPRLQLRVTCGSGTYIRSLVRDLGEIL 192

Query: 223 GVGGHMQELRR 233
           G G H+  LRR
Sbjct: 193 GCGAHINALRR 203

ref|YP_128837.1| putative tRNA pseudouridine 5S synthase [Photobacterium profundum SS9]
emb|CAG19035.1| putative tRNA pseudouridine 5S synthase [Photobacterium profundum SS9]
sp|Q6LUJ0|TRUB_PHOPR tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(316 aa)

Score: 83 bits (204), Expect: 1.41591e-14
Length: 202, Idn/Pos/Gap = 64/91/40 (31%/45%/19%)

Query:  64 RPIQEYIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERAT 123
           RPI      GVI LDKP   +S++ +  +KRI   +K GH+G LDP  TG L +C   AT
Sbjct:   8 RPI-----DGVILLDKPTGITSNDTLQKVKRIFFAQKAGHTGALDPLATGMLPICFGEAT  62

Query: 124 RLVKSQQSAGKEYVAVLRLHGMRP---------------ELDEATVRRAIETLTGPLYQR 168
           +  +    + K Y  + +L G R                ++D   + R I    G   Q 
Sbjct:  63 KFSQFLLDSDKRYRVIAKL-GERTNTSDSDGEVVETREVKVDRGQLERCIAKFRGTTDQI 121

Query: 169 PPLISAVK-----------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYI 211
           P + SA+K                 R+ R  T++  +LL ++     V   V C  GTYI
Sbjct: 122 PSMFSALKYQGRPLYEYAREGIEIPRESRKITVHSIELLRFEGHE--VEMEVHCSKGTYI 179

Query: 212 RTLCVHLGLLLGVGGHMQELRR 233
           RT+   LG +LG G H+  LRR
Sbjct: 180 RTITDDLGEMLGCGAHVVYLRR 201

ref|NP_893464.1| Putative tRNA pseudouridine 55 synthase [Prochlorococcus marinus subsp. pastoris str. CCMP1986]
emb|CAE19806.1| Putative tRNA pseudouridine 55 synthase [Prochlorococcus marinus subsp. pastoris str. CCMP1986]
sp|P59882|TRUB_PROMP tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(305 aa)

Score: 83 bits (204), Expect: 1.41591e-14
Length: 206, Idn/Pos/Gap = 62/102/36 (30%/49%/17%)

Query:  70 IRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQ 129
           I+ G I ++K    +SH+ V  I+++L ++K GH+GTLDP VTG L + I  ATR ++  
Sbjct:   3 IKDGFIAINKEKGFTSHDCVKQIRKLLGIKKVGHTGTLDPDVTGTLPIAIGSATRFIQ-Y  61

Query: 130 QSAGKEYVAVLRLHGMR----------------PELDEATVRRAIETLTGPLYQRPPLIS 173
              GK Y+  ++L G+R                P L    + + +    G + Q PP++S
Sbjct:  62 LPQGKTYIGQIQL-GIRTKTDDMQGEILNKKDWPVLSHKQLDKYLNNFRGIIQQVPPIVS 120

Query: 174 A--VKRQLRIRTIYESKLLEYDPK----RRLVLF-W----------VSCEAGTYIRTLCV 216
           +  V  +   +  ++++  E  PK      LVL  W          VSC +GTYIR++  
Sbjct: 121 SVHVNGERAYKKAFKNEEFELKPKEVEIEELVLNKWDQINGILEIKVSCSSGTYIRSIAR 180

Query: 217 HLGLLLGVGGHMQELRRVRS-GVHSE 241
            LG  L   G + +L+R+ + G H +
Sbjct: 181 DLGGSLDSEGCLLKLKRISACGFHEK 206

ref|YP_067441.1| Pseudouridine synthase.; Uracil hydrolyase.; tRNA pseudouridylate synthase B [Rickettsia typhi str. Wilmington]
gb|AAU03959.1| tRNA pseudouridylate synthase B; Pseudouridine synthase.; Uracil hydrolyase. [Rickettsia typhi str. Wilmington]
sp|Q68WN3|TRUB_RICTY tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(292 aa)

Score: 83 bits (204), Expect: 1.52633e-14
Length: 241, Idn/Pos/Gap = 64/104/52 (26%/43%/21%)

Query:  75 INLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAGK 134
           +N  KP   SS ++V  +K+I+   K GH+GTLD +  G L + +  AT+L++    A K
Sbjct:   6 LNFYKPKGISSAKLVNIVKKIIGKTKIGHAGTLDVEAEGILPLAVGEATKLIQLLIDAKK  65

Query: 135 EYVAVLRLHGMR----------------PELDEATVRRAIETLTGPLYQRPPLISAVKR- 177
            Y+  ++                     P  +EA          G + Q PP+ SA+K  
Sbjct:  66 TYIFSVKFGAQTDNGDYTGKVIASKNYIPSQEEAYA--VCSKFIGNIKQIPPMFSAIKVN 123

Query: 178 --------------QLRIR--TIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLL 221
                         +L+ R  TIY+ K L +D ++ +  ++  C  GTYIRTL   L L 
Sbjct: 124 GIRAYKLAREGKVVELKPRNVTIYDLKCLNFDKEKAIATYYTECSKGTYIRTLTEDLALS 183

Query: 222 LGVGGHMQELRRVRSGVHSEYDGM-----------------VTMHDVLDAQWLFDTTKDE 264
           L   G + ELRR + G+  E + +                 + +  +LD   + D T D+
Sbjct: 184 LQSLGFVIELRRTQVGIFKEENAIHIKASDAITKNFIDKKSIKIEAILDDILVLDATDDQ 243

Query: 265 S 265
           +
Sbjct: 244 A 244

ref|NP_360302.1| tRNA pseudouridine 55 synthase [Rickettsia conorii str. Malish 7]
gb|AAL03203.1| tRNA pseudouridine 55 synthase [Rickettsia conorii str. Malish 7]
sp|Q92HV5|TRUB_RICCN tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(345 aa)

Score: 82 bits (203), Expect: 1.65915e-14
Length: 205, Idn/Pos/Gap = 63/93/37 (30%/45%/18%)

Query:  75 INLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAGK 134
           +N+ KP   SS ++V+ +K+IL   K GH+GTLD +  G L   +  AT+L+     A K
Sbjct:   6 LNIYKPRGISSAQLVSIVKKILGKTKIGHAGTLDVEAEGILPFAVGEATKLIHLLVDARK  65

Query: 135 EYVAVLRLHGMR-----------------PELDEATVRRAIETLTGPLYQRPPLISAVKR 177
            Y+  ++  GM+                 P  +EA          G + Q PP  SA+K 
Sbjct:  66 TYIFTVKF-GMQTNSGDCAGKVIATKDCIPSQEEAYA--VCSKFIGNVTQIPPAFSALKV 122

Query: 178 ---------------QLRIR--TIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGL 220
                          +L+ R  TIY+ K L +D K     ++  C  GTYIRTL   L L
Sbjct: 123 NGVRAYKLAREGKKVELKPRNITIYDLKCLNFDEKNATATYYTECSKGTYIRTLAEDLAL 182

Query: 221 LLGVGGHMQELRRVRSGVHSEYDGM 245
            L   G + ELRR + G+  E + +
Sbjct: 183 SLQSLGFVIELRRTQVGIFKEENAI 207

ref|ZP_00046578.1| COG0130: Pseudouridine synthase [Lactobacillus gasseri]
(297 aa)

Score: 82 bits (203), Expect: 1.65915e-14
Length: 214, Idn/Pos/Gap = 68/98/49 (31%/45%/22%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           +G++ ++KP   +S + V  +++IL++ K GH+GTLDP+V G L + I +AT+L++    
Sbjct:   3 NGIVVVNKPRGVTSSDCVYKLRKILQIRKIGHAGTLDPEVNGVLPIAIGQATKLIELMHE  62

Query: 132 AGKEYVAVLRLHGM------RPELDEATVRR--------------AIETLTGPLYQRPPL 171
             K Y+      GM        +LD  T+                 +E LTG L Q PP+
Sbjct:  63 KPKSYIG----SGMFGRATDSYDLDGKTIAEEKINTPFTSNEIIAGMEKLTGKLEQVPPI 118

Query: 172 ISAVK-----------------RQLRIRTIYESKLL---EYDP--KRRLVLFWVSCEAGT 209
            SAV+                 R  R   +Y  +L    EYDP  K     F + C  GT
Sbjct: 119 YSAVRVNGKRLYEYARENIPVERPKRKVNVYSYELTQDPEYDPLEKTESFNFAIRCSKGT 178

Query: 210 YIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYD 243
           Y+R+L   LG  LGV   M  L R  S   S YD
Sbjct: 179 YVRSLVNDLGEELGVPAVMTSLTRTSS---SGYD 209

ref|ZP_00266153.1| COG0130: Pseudouridine synthase [Pseudomonas fluorescens PfO-1]
(305 aa)

Score: 82 bits (203), Expect: 1.7012e-14
Length: 195, Idn/Pos/Gap = 60/92/29 (30%/47%/14%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           SG+I LDKP   +S+  +  ++ +L  EK GH+G+LDP  TG L +C   AT+  +    
Sbjct:  12 SGIILLDKPLGFTSNAALQKVRWLLNAEKAGHTGSLDPLATGVLPLCFGEATKFSQYLLD  71

Query: 132 AGKEYVAVLRLHGMRPELD--------------EATVRRAIETLTGPLYQRPPLISAVKR 177
           + K Y  + +L       D              +A +   +    G + Q PP+ SA+KR
Sbjct:  72 SDKGYETLAQLGKTTTTADAEGEVLQERPVTVGQADIEAVLPKFRGQISQIPPMYSALKR 131

Query: 178 --QLRIRTIYESKLLEYDPKR----RLVL---------FWVSCEAGTYIRTLCVHLGLLL 222
             Q   +     +++E +P+     RL L           V C  GTYIRTL   +G  L
Sbjct: 132 DGQPLYKLARAGEVVEREPRSVTIARLELLAFEGDTARLAVDCSKGTYIRTLVEDIGEQL 191

Query: 223 GVGGHMQELRRVRSG 237
           G G ++ ELRR ++G
Sbjct: 192 GCGAYVAELRRTQAG 206

gb|AAQ00472.1| Pseudouridine synthase [Prochlorococcus marinus subsp. marinus str. CCMP1375]
ref|NP_875819.1| Pseudouridine synthase [Prochlorococcus marinus subsp. marinus str. CCMP1375]
sp|P59880|TRUB_PROMA tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(313 aa)

Score: 82 bits (203), Expect: 1.74432e-14
Length: 197, Idn/Pos/Gap = 61/93/35 (30%/47%/17%)

Query:  70 IRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQ 129
           I  G + ++KPA  +SH+ V  ++RI  +++ GH GTLDP VTG L + I +ATRL+   
Sbjct:   4 IALGFLVINKPAGLTSHDCVNRLRRIYGIKRIGHGGTLDPAVTGVLPIAIGKATRLLSFL  63

Query: 130 QSAGKEYVAVLRLHGMRPELD----------------EATVRRAIETLTGPLYQRPPLIS 173
            S  K Y   ++L G+    D                E ++   +    G + Q PP+ S
Sbjct:  64 PSP-KTYEGTIKL-GISTNTDDLTGETISEHSWDQVKENSILNCLNKFQGEIKQCPPIFS 121

Query: 174 AV--------KRQLR---------IRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCV 216
           +V        K+  R         +  IY  KL+ ++ K   +   V C  GTYIR+L  
Sbjct: 122 SVHINGERAYKKARRGEFFELPPKLIKIYRIKLINWNKKDGTIDLEVHCSPGTYIRSLAR 181

Query: 217 HLGLLLGVGGHMQELRR 233
            +G  LG GG + +L R
Sbjct: 182 DIGKKLGCGGALAKLNR 198

gb|EAA25318.1| tRNA pseudouridine 55 synthase [Rickettsia sibirica 246]
ref|ZP_00141909.1| tRNA pseudouridine 55 synthase [Rickettsia sibirica 246]
(345 aa)

Score: 82 bits (203), Expect: 1.96046e-14
Length: 205, Idn/Pos/Gap = 63/93/37 (30%/45%/18%)

Query:  75 INLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAGK 134
           +N+ KP   SS ++V+ +K+IL   K GH+GTLD +  G L   +  AT+L+     A K
Sbjct:   6 LNIYKPRGISSAQLVSIVKKILGKTKIGHAGTLDVEAEGILPFAVGEATKLIHLLIDARK  65

Query: 135 EYVAVLRLHGMR-----------------PELDEATVRRAIETLTGPLYQRPPLISAVKR 177
            Y+  ++  GM+                 P  +EA          G + Q PP  SA+K 
Sbjct:  66 TYIFTVKF-GMQTNSGDCAGKVIATKDCIPSQEEAYA--VCSKFIGNVTQIPPAFSALKV 122

Query: 178 ---------------QLRIR--TIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGL 220
                          +L+ R  TIY+ K L +D K     ++  C  GTYIRTL   L L
Sbjct: 123 NGVRAYKLAREEKKVELKPRNITIYDLKCLNFDEKNATATYYTECSKGTYIRTLAEDLAL 182

Query: 221 LLGVGGHMQELRRVRSGVHSEYDGM 245
            L   G + ELRR + G+  E + +
Sbjct: 183 SLQSLGFVIELRRTQVGIFKEENAI 207

ref|ZP_00146868.2| COG0130: Pseudouridine synthase [Psychrobacter sp. 273-4]
(380 aa)

Score: 82 bits (202), Expect: 2.37521e-14
Length: 201, Idn/Pos/Gap = 61/93/35 (30%/46%/17%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRV-----EKTGHSGTLDPQVTGCLIVCIERATRLV 126
           SGVI +DKP   +S +VV+ +K + +      +K GH+GTLDP  TG L +C+  AT+  
Sbjct:  22 SGVILVDKPQGMTSQQVVSKVKYLFKSPNHDSKKAGHTGTLDPMATGLLPICLGEATKFS  81

Query: 127 KSQQSAGKEYVAVLRLHGMRPELD-------EATVRRAIETLTGPLYQR--------PPL 171
             Q  A K Y A + L       D       EAT+    +T+   + Q+        PP+
Sbjct:  82 HYQLDADKSYQATILLGSQTDTGDADGQVTAEATISAFDDTMLDKIAQQFLGAQQQIPPM 141

Query: 172 ISAVKRQLRIRTIYESKLLEYD-PKRRLVL--------------FWVSCEAGTYIRTLCV 216
            SA+K+  +    Y    +E D P R ++L                V+C  GTY+R L  
Sbjct: 142 YSALKKDGKKLYEYARAGIEVDRPPRDIILKAIELKAIDEQQIQLTVTCSKGTYVRVLAE 201

Query: 217 HLGLLLGVGGHMQELRRVRSG 237
            +   +G  GH+  L R++ G
Sbjct: 202 DIAKAIGTLGHLTALSRLQVG 222

ref|ZP_00227837.1| COG0130: Pseudouridine synthase [Kineococcus radiotolerans SRS30216]
(291 aa)

Score: 82 bits (201), Expect: 2.69188e-14
Length: 205, Idn/Pos/Gap = 67/94/45 (32%/45%/21%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           G++ +DKP+  +SH+VV   +R+L   + GH+GTLDP  TG L++   R T+ +    + 
Sbjct:   4 GILVVDKPSGWTSHDVVGRCRRLLGTRRVGHAGTLDPAATGVLVLGANRGTKFLTHLVAH  63

Query: 133 GKEYVAVLRLHGMRPELDEA-----------------TVRRAIETLTGPLYQRPPLISAV 175
            K Y A +RL G+    D+A                  V  A+  LTG L Q P  +SA+
Sbjct:  64 DKAYAATIRL-GLATVTDDAEGEPLGAPADASALAPDAVAAAVSALTGDLQQVPSSVSAI 122

Query: 176 K-----RQLRIRTIYESKLLEYDPKRRLVL------------------FWVSCEAGTYIR 212
           K        R+R   E  L    P R + +                    V   +GTY+R
Sbjct: 123 KVDGQRSYARVRGGQEVDL----PARPVTVSRFDVLQRRAEGGFLDLDVVVEVSSGTYVR 178

Query: 213 TLCVHLGLLLGVGGHMQELRRVRSG 237
            L   LG  LGVGGH+  LRR RSG
Sbjct: 179 ALARDLGAALGVGGHLTALRRTRSG 203

gb|AAQ59139.1| tRNA pseudouridine 55 synthase [Chromobacterium violaceum ATCC 12472]
ref|NP_901134.1| tRNA pseudouridine 55 synthase [Chromobacterium violaceum ATCC 12472]
sp|Q7MBF7|TRUB_CHRVO tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(306 aa)

Score: 82 bits (201), Expect: 2.73718e-14
Length: 256, Idn/Pos/Gap = 75/111/42 (29%/43%/16%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           GV+ +DKP + SS+  +   + +L   K GH+G LDP  TG L VC+  AT+       A
Sbjct:  13 GVLLIDKPYDISSNNALQKARWLLNAAKAGHTGVLDPLATGLLPVCLGEATKFSSYLLDA  72

Query: 133 GKEYVAVLRLH-------------GMRP-ELDEATVRRAIETLTGPLYQRPPLISAVK-- 176
            K Y A +R                 RP E     +  A+    G + Q PP+ SA+K  
Sbjct:  73 DKGYRATVRFGVVTTTGDVEGEVVSERPVEFGREQLEAALARFRGEISQVPPMYSALKHQ 132

Query: 177 ---------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLL 221
                          R+ R  TI + +LL +D     +   V C  GTYIRTL   +G  
Sbjct: 133 GKPLYEYARAGIEVPREARQVTIRKLELLSFDGVSAEID--VLCTKGTYIRTLGCDIGEA 190

Query: 222 LGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPLESLLVHH 281
           LG G H+  LRR  +G  S    +   H + D + L D    E+ L     P + L++H 
Sbjct: 191 LGCGAHLTALRRTATGGFS----LDESHRLADLESL-DMPAREALL----MPADVLVMHF 241

Query: 282 KRIVIKDSCVNAVCYG 297
            ++ + D  +    +G
Sbjct: 242 PQLELADEEIGKFLHG 257

sp|Q5PAY2|TRUB_ANAMM tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
ref|YP_153803.1| tRNA pseudouridine 55 synthase [Anaplasma marginale str. St. Maries]
gb|AAV86548.1| tRNA pseudouridine 55 synthase [Anaplasma marginale str. St. Maries]
(306 aa)

Score: 82 bits (201), Expect: 2.78324e-14
Length: 205, Idn/Pos/Gap = 63/91/36 (30%/44%/17%)

Query:  70 IRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVK-- 127
           ++ G +N+DKP + SS  VV  +K+I    K GH+GTLDP  TG L V +  AT+ +   
Sbjct:   6 VKYGWLNVDKPLHMSSGSVVGRVKKIFNC-KVGHAGTLDPLATGVLPVAVGEATKTIPYA  64

Query: 128 --------------SQQSAGKEYVAVLRLHGMRPELDEATVRRAIETLTGPLYQRPPLIS 173
                         SQ+S       +++   +RP  D  ++R A+    G + Q PP  S
Sbjct:  65 VDGLKSYAVTVQWGSQRSTDDAEGEIIKTSSLRPSAD--SIREALGQFVGNIRQVPPAFS 122

Query: 174 AVK----RQLRIR-------------TIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCV 216
           AV+    R  R+               I    LL  D +     F + C+ G YIR+   
Sbjct: 123 AVRVRGVRAYRLARRGEAVSLPPKEVCIVSIDLLSADEESNTADFLIVCKKGVYIRSFAR 182

Query: 217 HLGLLLGVGGHMQELRRVRSGVHSE 241
            LG  LG  G++  LRR   G  SE
Sbjct: 183 DLGASLGCFGYVSFLRRKSVGPFSE 207

ref|ZP_00126290.1| COG0130: Pseudouridine synthase [Pseudomonas syringae pv. syringae B728a]
(305 aa)

Score: 82 bits (201), Expect: 3.10212e-14
Length: 195, Idn/Pos/Gap = 63/93/29 (32%/47%/14%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           SG+I LDKP   +S+  +  ++ +L  EK GH+G+LDP  TG L +C   AT+  +    
Sbjct:  12 SGIILLDKPLGFTSNAALQKVRWLLNAEKAGHTGSLDPLATGVLPLCFGEATKFSQYLLD  71

Query: 132 AGKEYVAVLRLHGMRPELDE---------ATVRR-----AIETLTGPLYQRPPLISAVKR 177
           + K Y  + +L       D           TV R     A+    G + Q PP+ SA+KR
Sbjct:  72 SDKSYETLAQLGKTTTTADSEGEVLLTRPVTVGRDDIEAALPHFRGQISQIPPMYSALKR 131

Query: 178 --QLRIRTIYESKLLEYDPKR----RLVLFW---------VSCEAGTYIRTLCVHLGLLL 222
             Q   +     +++E +P+     RL L           V C  GTYIRTL   +G  L
Sbjct: 132 DGQPLYKLARAGEVVEREPRSVTIARLELLACEGDTARLSVDCSKGTYIRTLVEDIGEKL 191

Query: 223 GVGGHMQELRRVRSG 237
           G G ++ ELRR ++G
Sbjct: 192 GCGAYVAELRRTQAG 206

ref|NP_297530.1| tRNA pseudouridine synthase B [Xylella fastidiosa 9a5c]
gb|AAF83050.1| tRNA pseudouridine synthase B [Xylella fastidiosa 9a5c]
sp|Q9PGR1|TRUB_XYLFA tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(302 aa)

Score: 82 bits (201), Expect: 3.2074e-14
Length: 196, Idn/Pos/Gap = 63/91/40 (32%/46%/20%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           G++ LDKPA  SS+  +   +R+LR +K GH+G+LDP  TG L +C   AT++      +
Sbjct:  13 GILLLDKPAGISSNSALQIARRLLRAKKGGHTGSLDPLATGLLPLCFGEATKIAGLLLGS  72

Query: 133 GKEYVAVLRLHGMR---------------PELDEATVRRAIETLTGPLYQRPPLISAVK- 176
            K Y A + L                   P LD   V   I  L G + QR P+ SA+K 
Sbjct:  73 TKAYDADVLLGTTTTTDDAEGAVLLTRPVPTLDAEMVDAVIPQLIGRIRQRAPIYSALKQ 132

Query: 177 -------------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVH 217
                              R++ +  I    L+   P+ +L    V+C +GTYIR+L   
Sbjct: 133 GGEPLYAKARRGEVVNAPVREVEVHAI--ELLVLATPRLQLR---VTCGSGTYIRSLVRD 187

Query: 218 LGLLLGVGGHMQELRR 233
           LG +LG G H+  LRR
Sbjct: 188 LGEILGCGAHITALRR 203

pdb|1K8W|A Chain A, Crystal Structure Of The E. Coli Pseudouridine Synthase Trub Bound To A T Stem-Loop Rna
(327 aa)

Score: 81 bits (199), Expect: 5.51683e-14
Length: 195, Idn/Pos/Gap = 59/91/35 (30%/46%/17%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           +GV+ LDKP   SS++ +  +KRI    + GH+G LDP  TG L +C+  AT+  +    
Sbjct:  25 NGVLLLDKPQGMSSNDALQKVKRIYNANRAGHTGALDPLATGMLPICLGEATKFSQYLLD  84

Query: 132 AGKEYVAVLRLHGMRPELDEA---------------TVRRAIETLTGPLYQRPPLISAVK 176
           + K Y  + RL G R +  +A                +  A++T  G + Q P + SA+K
Sbjct:  85 SDKRYRVIARL-GQRTDTSDADGQIVEERPVTFSAEQLAAALDTFRGDIEQIPSMYSALK 143

Query: 177 -----------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLG 219
                            R+ R  T+YE   + ++     +   + C  GTYIRT+   LG
Sbjct: 144 YQGKKLYEYARQGIEVPREARPITVYELLFIRHEGNE--LELEIHCSKGTYIRTIIDDLG 201

Query: 220 LLLGVGGHMQELRRV 234
             LG G H+  LRR+
Sbjct: 202 EKLGCGAHVIYLRRL 216

ref|ZP_00041589.1| COG0130: Pseudouridine synthase [Xylella fastidiosa Ann-1]
(300 aa)

Score: 80 bits (198), Expect: 6.04713e-14
Length: 196, Idn/Pos/Gap = 63/91/40 (32%/46%/20%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           G++ LDKPA  SS+  +   +R+LR +K GH+G+LDP  TG L +C   AT++      +
Sbjct:  11 GILLLDKPAGISSNSALQVARRLLRAKKGGHTGSLDPLATGLLPLCFGEATKIAGLLLDS  70

Query: 133 GKEYVAVLRLHGMR---------------PELDEATVRRAIETLTGPLYQRPPLISAVK- 176
            K Y A + L                   P LD   V   I  L G + QR P+ SA+K 
Sbjct:  71 TKAYDADVLLGTTTTTDDAEGAVLLTRPVPTLDAEMVDALIPQLIGRIRQRAPIYSALKQ 130

Query: 177 -------------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVH 217
                              R++ +  I    L+   P+ +L    V+C +GTYIR+L   
Sbjct: 131 GGEPLYAKARRGEVVNAPVREVEVHAI--ELLVLATPRLQLR---VTCGSGTYIRSLVRD 185

Query: 218 LGLLLGVGGHMQELRR 233
           LG +LG G H+  LRR
Sbjct: 186 LGEILGCGAHITALRR 201

ref|ZP_00357608.1| COG0130: Pseudouridine synthase [Chloroflexus aurantiacus]
(290 aa)

Score: 80 bits (198), Expect: 6.62841e-14
Length: 198, Idn/Pos/Gap = 66/94/33 (33%/47%/16%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRIL-RVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQ 130
           +G + +DKPA  +SH+VVA ++R+  R  K GH+GTLDP  TG L V +  ATRL+    
Sbjct:   5 TGFLVVDKPAGLTSHDVVARVRRLAGRAVKVGHAGTLDPAATGVLPVALGSATRLIDQLV  64

Query: 131 SAGKEYVAVLRLHGMRPELDE------ATVRRAIETLT----------GPLYQRPPLISA 174
            A K Y  V+RL G++   D+      AT+   + T+T          G + Q+PP  SA
Sbjct:  65 DARKGYRGVVRL-GVQTTTDDAEGEPVATLPVPVFTITEIAAVLAQFRGDILQQPPAFSA 123

Query: 175 V---------------KRQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLG 219
           +               +  L  R +   +L   D     +   V C  G YIR L   +G
Sbjct: 124 LHVAGQRAYALARAGDQVTLAPRLVRIDRLELLDWASPDLTIEVECGKGVYIRALARDIG 183

Query: 220 LLLGVGGHMQELRRVRSG 237
             LG GGH+  L+R   G
Sbjct: 184 AALGCGGHLVSLQRTFVG 201

ref|ZP_00038710.1| COG0130: Pseudouridine synthase [Xylella fastidiosa Dixon]
(300 aa)

Score: 80 bits (198), Expect: 7.38783e-14
Length: 196, Idn/Pos/Gap = 63/91/40 (32%/46%/20%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           G++ LDKPA  SS+  +   +R+LR +K GH+G+LDP  TG L +C   AT++      +
Sbjct:  11 GILLLDKPAGISSNSALQVARRLLRAKKGGHTGSLDPLATGLLPLCFGEATKIAGLLLDS  70

Query: 133 GKEYVAVLRLHGMR---------------PELDEATVRRAIETLTGPLYQRPPLISAVK- 176
            K Y A + L                   P LD   V   I  L G + QR P+ SA+K 
Sbjct:  71 TKAYDADVLLGTTTTTDDAEGAVLLTRPVPTLDAEMVDALIPQLIGRIRQRAPIYSALKQ 130

Query: 177 -------------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVH 217
                              R++ +  I    L+   P+ +L    V+C +GTYIR+L   
Sbjct: 131 GGEPLYVKARRGEVVNAPVREVEVHAI--ELLVLATPRLQLR---VTCGSGTYIRSLVRD 185

Query: 218 LGLLLGVGGHMQELRR 233
           LG +LG G H+  LRR
Sbjct: 186 LGEILGCGAHITALRR 201

ref|ZP_00333905.1| COG0130: Pseudouridine synthase [Thiobacillus denitrificans ATCC 25259]
(298 aa)

Score: 80 bits (198), Expect: 7.70256e-14
Length: 194, Idn/Pos/Gap = 66/87/29 (34%/44%/14%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           GV+ L+KP   +S+  +   K +L  +K GH+GTLDP   G L +C   AT+       A
Sbjct:  10 GVLLLNKPVGITSNAALQKAKWLLNAKKAGHTGTLDPFADGLLPLCFGEATKFSAYLLDA  69

Query: 133 GKEYVAVLRLHGMRPELDE--------------ATVRRAIETLTGPLYQRPPLISAVKRQ 178
            K Y A+L+L       D               A +R A+    G + Q PP+ SA+K Q
Sbjct:  70 DKRYRAILQLGVTTRTGDPEGEVLATREVRATCADIRAALPAFVGEIEQIPPMHSALKHQ 129

Query: 179 LRIRTIYESKLLEY--DPK----RRLVLFW---------VSCEAGTYIRTLCVHLGLLLG 223
            R    Y    +E    P+    R L LF          V C AGTY+RTL   LG  LG
Sbjct: 130 GRPLYEYARAGVEIARAPRRVHIRALDLFKCAPPRAVVDVQCSAGTYVRTLAEDLGNALG 189

Query: 224 VGGHMQELRRVRSG 237
            G H+  L R  SG
Sbjct: 190 CGAHLTALTRTASG 203

ref|ZP_00340365.1| COG0130: Pseudouridine synthase [Rickettsia akari str. Hartford]
(293 aa)

Score: 80 bits (197), Expect: 8.65698e-14
Length: 274, Idn/Pos/Gap = 74/123/53 (27%/44%/19%)

Query:  75 INLDKPANPSSHEVVAWIKRIL-RVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAG 133
           +N+ KP   SS ++V+ +K+IL +  K GH+GTLD +  G L + +  AT+L++    + 
Sbjct:   6 LNIYKPGGISSAKLVSMVKQILGKKVKVGHAGTLDVEAEGILPIAVGEATKLIQLLIDSR  65

Query: 134 KEYVAVLRLHGMR-----------------PELDEATVRRAIETLTGPLYQRPPLISAVK 176
           K Y+  ++  G++                 P  +EA          G + Q PP  SA+K
Sbjct:  66 KTYIFTIKF-GLQTDSGDYTGTVIATKNYIPSQEEAYT--VCSKFIGKVTQIPPAFSALK 122

Query: 177 -------------RQLRIR----TIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLG 219
                        +++ ++    TIY  K L +D K  + +++  C  GTYIRTL   L 
Sbjct: 123 VNGVRAYKFAREGKEVELKPRNITIYNLKCLNFDKKNAIAIYYTECSKGTYIRTLAEDLA 182

Query: 220 LLLGVGGHMQELRRVRSGVHSEYDGM-VTMHDVLDAQWLFDTTKDESYLRRVIKPLESLL 278
           L L   G + ELRR + G+    + + +   D        + TK  S+L      +E++L
Sbjct: 183 LSLQSLGFVIELRRTQVGIFKAENAIRIKSPD--------EITK--SFLEEKSIKIEAIL 232

Query: 279 VHHKRIVIKDSCVNAVCYGAKLMLPGVLRYENDI 312
                +   DS    + YG K     +  YE+DI
Sbjct: 233 DDILVLDATDSQAQQIKYGQKC----IFDYEDDI 262

ref|NP_708967.1| tRNA pseudouridine 5S synthase [Shigella flexneri 2a str. 301]
gb|AAN44674.1| tRNA pseudouridine 5S synthase [Shigella flexneri 2a str. 301]
ref|NP_838677.1| tRNA pseudouridine 5S synthase [Shigella flexneri 2a str. 2457T]
gb|AAP18488.1| tRNA pseudouridine 5S synthase [Shigella flexneri 2a str. 2457T]
sp|Q83MJ8|TRUB_SHIFL tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(314 aa)

Score: 80 bits (197), Expect: 9.33209e-14
Length: 195, Idn/Pos/Gap = 59/91/35 (30%/46%/17%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           +GV+ LDKP   SS++ +  +KRI    + GH+G LDP  TG L +C+  AT+  +    
Sbjct:  12 NGVLLLDKPQGMSSNDALQKVKRIYNANRAGHTGALDPLATGMLPICLGEATKFSQYLLD  71

Query: 132 AGKEYVAVLRLHGMRPELDEA---------------TVRRAIETLTGPLYQRPPLISAVK 176
           + K Y  + RL G R +  +A                +  A++T  G + Q P + SA+K
Sbjct:  72 SDKRYRVIARL-GQRTDTSDADGQIVEERPVTFSAEQLAAALDTFRGDIEQIPSMYSALK 130

Query: 177 -----------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLG 219
                            R+ R  T+YE   + ++     +   + C  GTYIRT+   LG
Sbjct: 131 YQGKKLYEYARQGIEVPREARPITVYELLFIRHEGNE--LELEIHCSKGTYIRTIIDDLG 188

Query: 220 LLLGVGGHMQELRRV 234
             LG G H+  LRR+
Sbjct: 189 EKLGCGAHVIYLRRL 203

ref|NP_106200.1| tRNA pseudouridine 55 synthase [Mesorhizobium loti MAFF303099]
sp|Q98BI6|TRUB_RHILO tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
dbj|BAB51986.1| tRNA pseudouridine 55 synthase [Mesorhizobium loti MAFF303099]
(325 aa)

Score: 80 bits (197), Expect: 9.89338e-14
Length: 202, Idn/Pos/Gap = 66/91/38 (32%/45%/18%)

Query:  64 RPIQEYIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERAT 123
           RP+     SG + LDKP    S E V+ IK + + EK GH+GTLDP  +G L + +  AT
Sbjct:  10 RPV-----SGWVVLDKPVGMGSTEAVSKIKWLFQAEKAGHAGTLDPLASGMLPIALGEAT  64

Query: 124 RLVKSQQSAGKEY---VA-------------VLRLHGMRPELDEATVRRAIETLTGPLYQ 167
           + V   Q   K Y   VA             V +   +RP   EA V+  +   TG + Q
Sbjct:  65 KTVPYVQDGAKIYRFTVAWGQERSTDDLEGPVTKSSDLRPA--EAEVKALLPKYTGVIMQ 122

Query: 168 RPPLISAVK---------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIR 212
            PP  SA+K                 +  R I   +L   +      +F V C  GTY+R
Sbjct: 123 TPPQFSAIKIAGERAYDLAREGETVDIPAREIEIGRLDIIEHHADHTVFEVECGKGTYVR 182

Query: 213 TLCVHLGLLLGVGGHMQELRRV 234
           +L   +G  LG  GH+ +LRRV
Sbjct: 183 SLARDMGRDLGCFGHISDLRRV 204

ref|NP_755789.1| tRNA pseudouridine synthase B [Escherichia coli CFT073]
emb|CAA31635.1| unnamed protein product [Escherichia coli]
emb|CAA32021.1| P35 gene product (AA 1 - 314) [Escherichia coli]
gb|AAN82363.1| tRNA pseudouridine synthase B [Escherichia coli CFT073]
ref|NP_417635.1| tRNA pseudouridine 5S synthase [Escherichia coli K12]
gb|AAC76200.1| tRNA pseudouridine 5S synthase [Escherichia coli K12]
sp|P60342|TRUB_ECO57 tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
sp|P60341|TRUB_ECOL6 tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
sp|P60340|TRUB_ECOLI tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase) (Protein p35)
gb|AAG58302.1| tRNA pseudouridine 5S synthase [Escherichia coli O157:H7 EDL933]
dbj|BAB37470.1| tRNA pseudouridine 5S synthase [Escherichia coli O157:H7]
ref|NP_312074.1| tRNA pseudouridine 5S synthase [Escherichia coli O157:H7]
pdb|1R3F|A Chain A, Crystal Structure Of Trna Pseudouridine Synthase Trub And Its Rna Complex: Rna-Protein Recognition Through A Combination Of Rigid Docking And Induced Fit
ref|NP_289742.1| tRNA pseudouridine 5S synthase [Escherichia coli O157:H7 EDL933]
(314 aa)

Score: 80 bits (196), Expect: 1.02291e-13
Length: 195, Idn/Pos/Gap = 59/91/35 (30%/46%/17%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           +GV+ LDKP   SS++ +  +KRI    + GH+G LDP  TG L +C+  AT+  +    
Sbjct:  12 NGVLLLDKPQGMSSNDALQKVKRIYNANRAGHTGALDPLATGMLPICLGEATKFSQYLLD  71

Query: 132 AGKEYVAVLRLHGMRPELDEA---------------TVRRAIETLTGPLYQRPPLISAVK 176
           + K Y  + RL G R +  +A                +  A++T  G + Q P + SA+K
Sbjct:  72 SDKRYRVIARL-GQRTDTSDADGQIVEERPVTFSAEQLAAALDTFRGDIEQIPSMYSALK 130

Query: 177 -----------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLG 219
                            R+ R  T+YE   + ++     +   + C  GTYIRT+   LG
Sbjct: 131 YQGKKLYEYARQGIEVPREARPITVYELLFIRHEGNE--LELEIHCSKGTYIRTIIDDLG 188

Query: 220 LLLGVGGHMQELRRV 234
             LG G H+  LRR+
Sbjct: 189 EKLGCGAHVIYLRRL 203

sp|Q8YWR1|TRUB_ANASP tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
dbj|BAB77909.1| tRNA pseudouridine synthase B [Nostoc sp. PCC 7120]
ref|NP_485583.1| tRNA pseudouridine synthase B [Nostoc sp. PCC 7120]
(293 aa)

Score: 80 bits (196), Expect: 1.23932e-13
Length: 201, Idn/Pos/Gap = 60/101/42 (29%/50%/20%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           G INL+K    +SH+ VA ++++LR+++ GH+GTLDP  TG L + + +ATRL++   S 
Sbjct:   3 GFINLNKQFGWTSHDCVARLRKMLRLKRVGHAGTLDPAATGVLPIAVGKATRLLQYLPS-  61

Query: 133 GKEYVAVLRLHGMRPELDE----------------ATVRRAIETLTGPLYQRPPLISAVK 176
            K Y A +R  G++   D+                + V+ A+    G + Q PP+ SA+ 
Sbjct:  62 DKAYKATVRF-GVQTTTDDLQGEIITSQPCRGLSLSEVKTALPQFIGKIEQIPPIYSAI- 119

Query: 177 RQLRIRTIYE----SKLLEYDPKRRLVLF------W-----------VSCEAGTYIRTLC 215
            Q+  + +Y+     +++E  P R + +F      W           ++C +GTYIR + 
Sbjct: 120 -QVEGKRLYDLARKGEIIEV-PARTVEVFSIDVLDWREGDFPELDVAIACGSGTYIRAIA 177

Query: 216 VHLGLLLGVGGHMQELRRVRS 236
             LG +   GG +  L R  S
Sbjct: 178 RDLGAVFHTGGTLAALIRTHS 198

ref|YP_203871.1| tRNA pseudouridine synthase B [Vibrio fischeri ES114]
gb|AAW84983.1| tRNA pseudouridine synthase B [Vibrio fischeri ES114]
sp|Q5E7L3|TRUB_VIBF1 tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(316 aa)

Score: 78 bits (193), Expect: 2.31716e-13
Length: 324, Idn/Pos/Gap = 90/146/58 (27%/45%/17%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           +GVI +DKP   +S++ +  +KRI   EK GH+G LDP  TG L +C+  AT+  +    
Sbjct:  11 NGVILIDKPTGITSNDTLQKVKRIYFAEKAGHTGALDPLATGMLPICLGEATKFSQFLLD  70

Query: 132 AGKEYVAVLRLHGMRP---------------ELDEATVRRAIETLTGPLYQRPPLISAVK 176
           + K Y  V +L G R                ++D   + R I    G   Q P + SA+K
Sbjct:  71 SDKRYRVVAKL-GERTNTSDSDGEVVQTREVKVDRGQLERCIAKFRGTTDQIPSMFSALK 129

Query: 177 -----------------RQLRIRTIYESKLLEYDPKRRLVLFWVSC-EAGTYIRTLCVHL 218
                            R+ R  T+Y  +LL ++     V   V C +A T++R L   L
Sbjct: 130 YQGRPLYEYAREGIEVPRESRKITVYSIELLRFEGHE--VEMEVHCSKALTFVR-LPTIL 186

Query: 219 GLLLGVGGHMQELRRVRSGVHS-EYDGMVTMHDV--LDAQWLFDTTKDESYLRRVIKPLE 275
           G +LG G H+  LR  R+GV +  Y+ MVT+ D+  L  Q   +       L  ++ P++
Sbjct: 187 GEMLGCGAHVTYLR--RTGVSNYPYENMVTIEDLEALLEQAHREERAPRELLDPLLMPMD 244

Query: 276 SLLVHHKRIVIKDSCVNAVCYGAKLMLPGVLRYENDIECGEEVVIMTTKGEAVALAIAHM 335
           S +     + +     + V +G  + + G  +        + +V MT+  E + + + H+
Sbjct: 245 SAVQDLPEVNMIPELADHVLHGQPVQVFGAPQ--------DGIVRMTSGDERLFIGVGHI 296

Query: 336 STSEIASCDHGVVARIKRVVMERD 359
                   D G VA  KR+V+ RD
Sbjct: 297 D-------DDGRVAP-KRLVVFRD 312

ref|YP_194117.1| tRNA pseudouridine synthase B [Lactobacillus acidophilus NCFM]
gb|AAV43086.1| tRNA pseudouridine synthase B [Lactobacillus acidophilus NCFM]
sp|Q5FJN8|TRUB_LACAC tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(297 aa)

Score: 78 bits (193), Expect: 2.69266e-13
Length: 204, Idn/Pos/Gap = 62/93/40 (30%/45%/19%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           +G+I +DK    +S +VV  ++R L + K GH+GTLDP+VTG L + I +AT+L++   +
Sbjct:   3 NGIIVIDKDKGMTSADVVYHLRRALHIRKIGHAGTLDPEVTGVLPIAIGQATKLIELMHT  62

Query: 132 AGKEYVA----------------VLRLHGMRPELDEATVRRAIETLTGPLYQRPPLISAV 175
             K+Y                  VL+   +        ++R + T  G + Q PP+ SAV
Sbjct:  63 RPKKYQGTGLFGYATDSYDIDGKVLKEKRLVMPFTVEEIQRGMNTFKGKIEQVPPIYSAV 122

Query: 176 K-----------------RQLRIRTIYESKLLEYDPK------RRLVLFWVSCEAGTYIR 212
           K                 R  R   I++  LL  DP       +    F ++C  GTY+R
Sbjct: 123 KVNGKHLYEYAREGIKVERPKRQVEIFQYDLLN-DPSFDKEKGQESFDFEITCSKGTYVR 181

Query: 213 TLCVHLGLLLGVGGHMQELRRVRS 236
           +L   LG  L     M  LRRV S
Sbjct: 182 SLVNDLGEKLDEPAVMTYLRRVAS 205

emb|CAD84674.1| tRNA pseudouridine synthase B [Nitrosomonas europaea ATCC 19718]
ref|NP_840837.1| tRNA pseudouridine synthase B [Nitrosomonas europaea ATCC 19718]
sp|Q820P2|TRUB_NITEU tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(308 aa)

Score: 78 bits (193), Expect: 2.80737e-13
Length: 247, Idn/Pos/Gap = 69/108/46 (27%/43%/18%)

Query:  77 LDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAGKEY 136
           L+KP+  SS+  +   KR+L   K GH+GTLDP   G L +C+  AT+   +     K Y
Sbjct:   2 LNKPSGISSNRALQISKRLLSAAKAGHTGTLDPMAQGLLPICLGEATKFSSTLLGVDKTY  61

Query: 137 VAVLRLHGMRPELD-EATVRRAI----------------ETLTGPLYQRPPLISAVKRQL 179
           +A LRL  +    D E  +R+ +                +T  G   Q PP+ SA+K+  
Sbjct:  62 IASLRLGYISNTGDAEGEIRQVVGSDVNPPDFGQVTGILQTFLGRSSQIPPMFSALKQHG 121

Query: 180 RIRTIYESKLLEYDPKRRLVLFW---------------VSCEAGTYIRTLCVHLGLLLGV 224
           +    Y  + +  + K R ++                 V C +GTY+RTL   +G  LG 
Sbjct: 122 KPLYRYAREGITVERKAREIVIHAASLDTLSGFEMTITVRCSSGTYVRTLAEDIGKALGY 181

Query: 225 GG-HMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRR--VIKPLESLLVHH 281
           GG ++  L R+  G           H  L      D  + E+ + R  ++ P++SLL   
Sbjct: 182 GGAYLTALSRISVG-----------HFELSQACDLDQLESETPVNRQKLLCPIDSLLNDI 230

Query: 282 KRIVIKD 288
             IV+ D
Sbjct: 231 PSIVLDD 237

ref|ZP_00385683.1| COG0130: Pseudouridine synthase [Lactobacillus casei ATCC 334]
(306 aa)

Score: 78 bits (192), Expect: 3.63608e-13
Length: 211, Idn/Pos/Gap = 66/91/52 (31%/43%/24%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           +G++ L KP   +S + V   ++IL ++K GHSGTLDP V G L + I   T+ V    +
Sbjct:   7 NGILPLYKPTGMTSADAVYHARKILGIKKIGHSGTLDPNVDGVLPLAIGAGTKAVPQLMA  66

Query: 132 AGKEYVA--VLRLHGMRPELDEATVRR--------------AIETLTGPLYQRPPLISAV 175
           +GK Y     L       +LD   V +              A+   TG + Q PP+ SAV
Sbjct:  67 SGKVYTGEITLGFATTTEDLDGEVVDKTPLTQPFTADQLDAALTAWTGNITQIPPMFSAV 126

Query: 176 KRQLRIRTIYESKLLEY--------DPKRRLVL---------------------FWVSCE 206
           K   R       +L EY         P+R+  +                     F V   
Sbjct: 127 KVNGR-------RLYEYARAGETVKRPERQATVSQFTRTDEPVFSATDGTQRFRFEVHVS 179

Query: 207 AGTYIRTLCVHLGLLLGVGGHMQELRRVRSG 237
            GTYIRTL V +G  LGV   M +L RV+SG
Sbjct: 180 KGTYIRTLAVDVGKTLGVAAVMSQLTRVKSG 210

gb|AAO78319.1| tRNA pseudouridine synthase B [Bacteroides thetaiotaomicron VPI-5482]
ref|NP_812125.1| tRNA pseudouridine synthase B [Bacteroides thetaiotaomicron VPI-5482]
sp|Q8A2U2|TRUB_BACTN tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(240 aa)

Score: 78 bits (192), Expect: 3.75948e-13
Length: 222, Idn/Pos/Gap = 74/102/47 (33%/45%/21%)

Query:  74 VINLDKPANPSSHEVVAWIK-----RI-LRVEKTGHSGTLDPQVTGCLIVCIERATRLVK 127
           V+  +KP   +S +VV  ++     RI ++  K GH+GTLDP  TG +I+C  +AT+ ++
Sbjct:   8 VLFFNKPLGWTSFKVVGHVRYHICRRIGVKKLKVGHAGTLDPLATGVMILCTGKATKRIE  67

Query: 128 SQQSAGKEYVAVLRLHGMRPELD-----EAT-----VRRAI--ETLT---GPLYQRPPLI 172
             Q   KEYVA LRL    P  D     +AT     + R +  ETLT   G + Q PP  
Sbjct:  68 EFQYHTKEYVATLRLGATTPSYDLEHEIDATYPTGHITRELVEETLTHFLGAIEQVPPAF 127

Query: 173 SA-----------------VKRQLRIRTIYESKLLE--YDPKRRLVLFWVSCEAGTYIRT 213
           SA                 V+ + +   I E +LLE   D     +   V C  GTYIR 
Sbjct: 128 SACMVDGKRAYELARKGEEVELKAKQLVIDEIELLECRLDDPEPTIRIRVVCSKGTYIRA 187

Query: 214 LCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQ 255
           L   +G  L  G H+ EL R R        G V + D LD +
Sbjct: 188 LARDIGEALQSGAHLTELIRTRV-------GDVRLEDCLDPE 222

gb|AAF10895.1| tRNA pseudouridine 55 synthase, putative [Deinococcus radiodurans]
sp|Q9RUQ9|TRUB_DEIRA tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
ref|NP_295047.1| tRNA pseudouridine 55 synthase, putative [Deinococcus radiodurans R1]
(308 aa)

Score: 78 bits (191), Expect: 4.51698e-13
Length: 243, Idn/Pos/Gap = 69/109/63 (28%/44%/25%)

Query:  74 VINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAG 133
           VI  DKP + +SH+VV   +R L  ++ GH+GTLDP  TG +++C++ +T+LV+  +   
Sbjct:   3 VIAADKPLHLTSHDVVNRARRALGTKRVGHTGTLDPLATGVVVLCVDDSTKLVQFMEHDT  62

Query: 134 KEYVAVLRL---------------HGMRPELDEATVRRAIETLTGPLYQRPPLISAVK-- 176
           KEY+A + L                   P LDE  +R  ++   GP  Q PP  SA++  
Sbjct:  63 KEYLAWVSLGAGTPTLDAEGPIEQQAEVPPLDEDHLREVLKGFLGPQQQIPPQYSAIQIG 122

Query: 177 -----------RQL----RIRTIYESKLL-----------EYDPKR-------------- 196
                       QL    R   I+E +L+            +DP+               
Sbjct: 123 GQRAYAVARAGGQLDLPARDVEIHELELIGMFPSVQAAPRTFDPQSWTPAAAGLTFTLPE 182

Query: 197 -----RLVLFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDV 251
                  +L      +GTY+R+L   LG  LGV  H+  L R R+G +S  D  V++ ++
Sbjct: 183 PLGEFPTLLLRAHVGSGTYLRSLARDLGAALGVPAHLGGLVRTRAGRYSLRDA-VSLENL 241

Query: 252 LDA 254
            +A
Sbjct: 242 TEA 244

ref|YP_097340.1| tRNA pseudouridine synthase B [Bacteroides fragilis YCH46]
emb|CAH05847.1| putative tRNA pseudouridine synthase [Bacteroides fragilis NCTC 9343]
ref|YP_209809.1| putative tRNA pseudouridine synthase [Bacteroides fragilis NCTC 9343]
sp|Q650L8|TRUB_BACFR tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
dbj|BAD46806.1| tRNA pseudouridine synthase B [Bacteroides fragilis YCH46]
(233 aa)

Score: 77 bits (190), Expect: 5.24896e-13
Length: 203, Idn/Pos/Gap = 65/97/42 (32%/47%/20%)

Query:  74 VINLDKPANPSSHEVVAWIK----RILRVEK--TGHSGTLDPQVTGCLIVCIERATRLVK 127
           V+  +KP   +S +VV   +    R ++V+K   GH+GTLDP  TG +IVC  +AT+ ++
Sbjct:   8 VLYFNKPLGWTSFKVVGHARYHMCRRMKVKKLKVGHAGTLDPLATGVMIVCTGKATKRIE  67

Query: 128 SQQSAGKEYVAVLRLHGMRPELD-----EAT----------VRRAIETLTGPLYQRPPLI 172
             Q   KEYVA ++L    P  D     +AT          V + ++T  G + Q PP  
Sbjct:  68 EFQYHTKEYVATIQLGATTPSYDLEHEIDATYPTEHITRELVEKTLKTFVGEIQQIPPAF 127

Query: 173 SA-----------------VKRQLRIRTIYESKLLEYD-PKRRLVLFWVSCEAGTYIRTL 214
           SA                 V+ + ++  I E +LLE + P+ ++    V C  GTYIR L
Sbjct: 128 SACKVDGARAYDLARKGQEVELKPKLLVIDEIELLECNLPEIKIR---VVCSKGTYIRAL 184

Query: 215 CVHLGLLLGVGGHMQELRRVRSG 237
              +G  L  G H+  L R R G
Sbjct: 185 ARDIGEALQSGAHLTGLIRTRVG 207

ref|ZP_00055819.2| COG0130: Pseudouridine synthase [Magnetospirillum magnetotacticum MS-1]
(311 aa)

Score: 77 bits (190), Expect: 5.33729e-13
Length: 203, Idn/Pos/Gap = 62/87/30 (30%/42%/14%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           G + +DKP    S +VVA +KRIL   K GH GTLDP  +G L + +  AT+ V+     
Sbjct:  12 GWLAIDKPLGIGSTQVVAKVKRILNAAKVGHGGTLDPLASGILPIALGEATKTVQYVMDG  71

Query: 133 GKEYVAVLRLHGMRPELDEAT--------------VRRAIETLTGPLYQRPPLISAVK-- 176
            K Y   LR        D+ +              ++ A+    G + Q PP  SA+K  
Sbjct:  72 AKTYRFQLRWGEATASCDKESEVIETSPVRPSAEAIQAALPGFVGEIDQIPPAFSAIKID 131

Query: 177 -----------RQLRI---RTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLLL 222
                      +++ I   R    S  L   P      F V C  GTY+R+L   L L L
Sbjct: 132 GQRAYDLARAGQEVEIKPRRVAIHSFTLLGQPDSDHADFQVHCGKGTYVRSLARDLALAL 191

Query: 223 GVGGHMQELRRVRSGVHSEYDGM 245
           G  GH+  LRR   G  +E + +
Sbjct: 192 GTVGHVSVLRRTACGPFTEQNAI 214

ref|YP_033066.1| tRNA pseudouridine synthase B [Bartonella henselae str. Houston-1]
emb|CAF27025.1| tRNA pseudouridine synthase B [Bartonella henselae str. Houston-1]
sp|Q6G5F5|TRUB_BARHE tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(319 aa)

Score: 77 bits (190), Expect: 5.47257e-13
Length: 311, Idn/Pos/Gap = 88/134/59 (28%/43%/18%)

Query:  64 RPIQEYIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERAT 123
           RP+     SG I LDKP    S E V+ IK +   +K GH+GTLDP  +G L + +  AT
Sbjct:  10 RPV-----SGWIILDKPKGMRSTEAVSQIKYLFHAQKVGHAGTLDPLASGLLPIALGEAT  64

Query: 124 RLVKSQQSAGKEYVAVLRLH----------GMRPELDEATVRRA--------IETLTGPL 165
           + V       K Y    R H           +  E+   + +R         +   TG +
Sbjct:  65 KTVPYVMQGTKTY----RFHIAWGEERSTDDLEGEITHTSSKRPTREEILALLPQYTGVI 120

Query: 166 YQRPPLISAVK--------------------RQLRIRTIYESKLLEYDPKRRLVLFWVSC 205
            Q PP  SA+K                    RQ+ I T    KL+E   K   + F ++C
Sbjct: 121 LQTPPQFSAIKIAGNRAYDLAREGEVVEIPPRQVEIETF---KLIEMITKDHSI-FEITC 176

Query: 206 EAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDES 265
             GTY+R+L   +G  LG   H+ +LRR+      E D ++T  D L A  L  + K+E 
Sbjct: 177 GKGTYVRSLARDMGRDLGCYAHIADLRRIAVAPFCEND-LITW-DELKAVELDKSAKNEK 234

Query: 266 ---YLRRVIKPLESLLVHHKRIVIKDSCVNAVCYGAKLMLPG--VLRYENDIECGEEVVI 320
              + R  IK L+ LL+     +   S        A+ ++ G  VL Y +D+   E+ V 
Sbjct: 235 DAPFERNFIK-LDELLIETISALECLSHYTLSQTQAQQVMKGNTVLLYHHDVPLDEDEVC 293

Query: 321 MTTKGEAVALA 331
           +  + + +A+ 
Sbjct: 294 VLYQDQLLAIG 304

gb|AAA57969.1| P35 [Escherichia coli]
(314 aa)

Score: 77 bits (190), Expect: 5.51843e-13
Length: 195, Idn/Pos/Gap = 58/90/35 (29%/46%/17%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           +GV+ LDKP   SS++ +  +KRI    + GH+G LDP  TG L +C+  AT+  +    
Sbjct:  12 NGVLLLDKPQGMSSNDALQKVKRIYNANRAGHTGALDPLATGMLPICLGEATKFSQYLLD  71

Query: 132 AGKEYVAVLRLHGMRPELDEA---------------TVRRAIETLTGPLYQRPPLISAVK 176
           + K Y  + RL G R +  +A                +  A++T  G + Q P + SA+K
Sbjct:  72 SDKRYRVIARL-GQRTDTSDADGQIVEERPVTFSAEQLAAALDTFRGDIEQIPSMYSALK 130

Query: 177 -----------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLG 219
                            R+    T+YE   + ++     +   + C  GTYIRT+   LG
Sbjct: 131 YQGKKLYEYARQGIEVPREAXPITVYELLFIRHEGNE--LELEIHCSKGTYIRTIIDDLG 188

Query: 220 LLLGVGGHMQELRRV 234
             LG G H+  LRR+
Sbjct: 189 EKLGCGAHVIYLRRL 203

ref|NP_950489.1| pseudouridine synthase [Onion yellows phytoplasma OY-M]
sp|Q6YQY6|TRUB_ONYPE tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
dbj|BAD04322.1| pseudouridine synthase [Onion yellows phytoplasma OY-M]
(283 aa)

Score: 77 bits (188), Expect: 9.41301e-13
Length: 267, Idn/Pos/Gap = 70/117/42 (26%/43%/15%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           +G   ++KP   +SH+VV  IK+    +K GH+GTLDP  +G LI+C+ +AT+L      
Sbjct:   2 NGFFLVNKPEKMTSHDVVFQIKKKFHFDKVGHTGTLDPLASGLLIICVGKATKLAFLFDK  61

Query: 132 AGKEYVAVLRLHGMRPELD--------------EATVRRAIETLTGPLY-QRPPLISAVK 176
             K Y      +     LD              +  ++++  +     Y Q PP+ SAVK
Sbjct:  62 LPKTYQGTFLFNKHYDTLDVTGKLLDTKNTPLTDCNIQKSFASFHQKKYLQIPPMFSAVK 121

Query: 177 RQLR--IRTIYESKLLEYDPK--------------RRLVLFWVSCEAGTYIRTLCVHLGL 220
            + +   R   ++++++  P+              R  V F      GTYIR+L   L L
Sbjct: 122 IKGKKMYRLARKNQVVDIPPREVFIHHFEKTSLFCRDQVDFLAHVSKGTYIRSLARDLAL 181

Query: 221 LLGVGGHMQELRRVRSGVHSEYDGM----VTMHD-VLDAQWL--FDTTKDESYLRRVIKP 273
            L   G +  L+R   G H   +      + ++D +LD+ +   +D      YL +++K 
Sbjct: 182 QLNTYGALLRLQRTAIGTHLLQNAKTIENLELNDLILDSTFFAAYDELILNDYLIKLVKN 241

Query: 274 LESL----LVHHKRIVIKDSCVNAVCY 296
              L    +   K  ++KDS  N V Y
Sbjct: 242 GTHLDQRQITTKKPFIVKDSNKNFVAY 268

ref|NP_353120.1| hypothetical protein AGR_C_127 [Agrobacterium tumefaciens str. C58]
ref|NP_530794.1| tRNA pseudouridine 55 synthase [Agrobacterium tumefaciens str. C58]
gb|AAL41110.1| tRNA pseudouridine 55 synthase [Agrobacterium tumefaciens str. C58]
gb|AAK85905.1| AGR_C_127p [Agrobacterium tumefaciens str. C58]
sp|Q8UJ53|TRUB_AGRT5 tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(315 aa)

Score: 77 bits (188), Expect: 9.49188e-13
Length: 303, Idn/Pos/Gap = 83/120/45 (27%/39%/14%)

Query:  61 PLKRPIQEYIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIE 120
           P  RPI     SG + LDKP +  S E V+ IK +   +K GH+GTLDP  +G L + + 
Sbjct:  12 PKGRPI-----SGWLILDKPLDFGSTEAVSKIKWLFNAQKAGHAGTLDPLASGMLPIALG  66

Query: 121 RATRLVKSQQSAGKEYV----------------AVLRLHGMRPELDEATVRRAIETLTGP 164
            AT+ V       K Y                  V+     RPE  E  +R  +   TG 
Sbjct:  67 DATKTVPYVMDGRKIYEFTVTWGEQRATDDLEGEVVESSDQRPE--EQAIRDILPNYTGV 124

Query: 165 LYQRPPLISAVK---------------RQLRIRTIYESKL-LEYDPKRRLVLFWVSCEAG 208
           + Q PP  SA+K                ++  R +   +L L   P      F V C  G
Sbjct: 125 IMQTPPQFSAIKIAGERAYDLARDGETVEIPAREVEIHRLTLLACPDADTAHFEVECGKG 184

Query: 209 TYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLR 268
           TY+R L   +G  LG  GH+ ELRR       E D MV +  +   + + D  +    L 
Sbjct: 185 TYVRALARDMGRDLGCFGHISELRRTMVAPFGE-DMMVPLETLTALEAIEDRDERLEALD 243

Query: 269 RVIKPLESLLVHHKRIVIKDSCVNAVCYGAKLMLPGVLRYENDIECGEEVVIMTTKGEAV 328
             +      L    R++I D   + +  G  ++L G      D          T +G+ V
Sbjct: 244 AFLIDTAEALSSLPRLIINDDQAHRLKMGNPILLRG-----RDAPANHPEAYATAQGKLV 298

Query: 329 ALA 331
           A+ 
Sbjct: 299 AIG 301

ref|NP_878413.1| tRNA pseudouridine 5S synthase [Candidatus Blochmannia floridanus]
emb|CAD83627.1| tRNA pseudouridine 5S synthase [Candidatus Blochmannia floridanus]
sp|P59877|TRUB_CANBF tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(255 aa)

Score: 77 bits (188), Expect: 1.01471e-12
Length: 194, Idn/Pos/Gap = 52/86/29 (26%/44%/14%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           G++ LDKP   SS   +  IK++   +K G+ GTLDP  TG L +C  +AT+      ++
Sbjct:  17 GLLLLDKPTGFSSSFFLNKIKKLFYAKKVGYIGTLDPIATGMLPICFGKATKFASYLLNS  76

Query: 133 GKEYVAVLRLHGMRPELDEATV--------------RRAIETLTGPLYQRPPLISAVKRQ 178
            K Y  +++L       D + V                 +++  G   Q PP+ S++K Q
Sbjct:  77 DKRYRVLVKLGESTDTFDASGVIIRIADVQCNKEKIEECLKSFLGTSLQIPPMFSSLKYQ 136

Query: 179 ---------------LRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLLLG 223
                           + RTI+   L   +    ++   + C  GTY+R++   +G  LG
Sbjct: 137 GLPLYKYARRGVNIPRKSRTIHVYSLYCLNQLNSIIELEIHCSKGTYVRSIVNDIGEYLG 196

Query: 224 VGGHMQELRRVRSG 237
            G H+  LRR+  G
Sbjct: 197 CGAHIISLRRLMVG 210

ref|YP_031910.1| tRNA pseudouridine synthase B [Bartonella quintana str. Toulouse]
emb|CAF25704.1| tRNA pseudouridine synthase B [Bartonella quintana str. Toulouse]
sp|Q6G0P4|TRUB_BARQU tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(270 aa)

Score: 77 bits (188), Expect: 1.03178e-12
Length: 216, Idn/Pos/Gap = 63/93/43 (29%/43%/19%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           SG +  DKP    S E V+ IK +   +K GH+GTLDP  +G L + +  AT+ V     
Sbjct:  13 SGWVIFDKPKGMRSTEAVSQIKWLFHAQKAGHAGTLDPLASGLLPIALGEATKTVPYVMQ  72

Query: 132 AGKEYV----------------AVLRLHGMRPELDEATVRRAIETLTGPLYQRPPLISAV 175
             K Y                  +  +   RP  +E  +   +   TG + Q PP  SA+
Sbjct:  73 GTKTYRFQIAWGEERSTDDLEGEITHISSKRPTQEE--ILALLPQYTGVILQTPPQFSAI 130

Query: 176 K--------------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLC 215
           K                    RQ+ I T    KL+E  P R   +F ++C  GTY+R+L 
Sbjct: 131 KITGNRAYDLAREGKVVEIPPRQVEIETF---KLIE-TPTRERSVFEITCGKGTYVRSLA 186

Query: 216 VHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDV 251
             +G  LG  GH+ +LRR       E D ++T  ++
Sbjct: 187 RDMGRDLGCYGHIADLRRTTVAPFCE-DDLITWEEL 221

emb|CAC41678.1| PROBABLE TRNA PSEUDOURIDINE SYNTHASE B PROTEIN [Sinorhizobium meliloti]
ref|NP_384347.1| PROBABLE TRNA PSEUDOURIDINE SYNTHASE B PROTEIN [Sinorhizobium meliloti 1021]
sp|Q92SW2|TRUB_RHIME tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(311 aa)

Score: 77 bits (188), Expect: 1.08475e-12
Length: 275, Idn/Pos/Gap = 77/115/39 (28%/41%/14%)

Query:  61 PLKRPIQEYIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIE 120
           P  RPI     SG + LDKP +  S E V+ IK + + +K GH+GTLDP  +G L + + 
Sbjct:   7 PKGRPI-----SGWLILDKPLDFGSTEAVSKIKWLFKAQKAGHAGTLDPLASGMLPIALG  61

Query: 121 RATRLVKSQQSAGKEY---VA-------------VLRLHGMRPELDEATVRRAIETLTGP 164
            AT+ V       K Y   VA              +R    RPE  E  +R  +   TG 
Sbjct:  62 DATKTVPYVMDGRKIYEFTVAWGEERSTDDLEGEAVRSSAARPE--EEAIRALLPKYTGV 119

Query: 165 LYQRPPLISAVK---------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGT 209
           + Q PP  SA+K                ++  R +   +L        L  F + C  GT
Sbjct: 120 IAQVPPQFSAIKIGGERAYDLARDGETVEIPAREVEVFRLSLIGSAPNLAHFEIECGKGT 179

Query: 210 YIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRR 269
           Y+R+L   +G  LG  GH+  LRR       E D MV + D++  + + D  +  + L  
Sbjct: 180 YVRSLARDMGRDLGCFGHIASLRRTFVAPFGEED-MVPLADLVALEAIEDDAERLAALDA 238

Query: 270 VIKPLESLLVHHKRIVIKDSCVNAVCYGAKLMLPG 304
            +      L     I + D   + +  G  ++L G
Sbjct: 239 YLIDTGEALSDLPHIAVNDDQAHRLRMGNPIILRG 273

ref|YP_053523.1| tRNA pseudouridine 5S synthase [Mesoplasma florum L1]
gb|AAT75639.1| tRNA pseudouridine 5S synthase [Mesoplasma florum L1]
sp|Q6F1I4|TRUB_MESFL tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(286 aa)

Score: 77 bits (188), Expect: 1.12157e-12
Length: 205, Idn/Pos/Gap = 59/89/45 (28%/43%/21%)

Query:  71 RSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQ 130
           +SG+I L+KP   +++ ++  +KR L V+K GH+GTLDP  TG +I  I   T+L     
Sbjct:   3 KSGIIILNKPKGLTTNHLIQKLKRKLNVKKIGHAGTLDPLATGVVICLINNGTKLSDYFL  62

Query: 131 SAGKEYVAVLRL--------------HGMRP-ELDEATVRRAIETLTGPLY-QRPPLISA 174
           +  K Y   ++L                  P ++++  V + I    G  Y Q PP+ SA
Sbjct:  63 NENKAYEVTMKLFQATDTYDSDGSIIEEQEPFKIEQEQVEKVIAKFNGLAYEQEPPMYSA 122

Query: 175 VKRQLRIRTIYESKLLEYDPKRRLV----------------------LFWVSCEAGTYIR 212
           +K       I   KL EY  + ++V                         V C  GTYIR
Sbjct: 123 IK-------IDGKKLYEYARENQVVKVNKRLIKINSLSLDKYENNEISMTVYCSKGTYIR 175

Query: 213 TLCVHLGLLLGVGGHMQELRRVRSG 237
           +L V +   L    H+  L R+ SG
Sbjct: 176 SLIVDIAKELNTIAHVTSLNRIESG 200

ref|ZP_00005893.1| COG0130: Pseudouridine synthase [Rhodobacter sphaeroides 2.4.1]
(301 aa)

Score: 76 bits (187), Expect: 1.34755e-12
Length: 205, Idn/Pos/Gap = 65/92/32 (31%/44%/15%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           SG + +DKPA  +S  VV  ++  L  +K GH+GTLDP  TG L V +  AT+ V     
Sbjct:  11 SGWLVVDKPAGMTSTAVVNKVRWALEAQKAGHAGTLDPDATGVLAVALGEATKTVPYITD  70

Query: 132 AGKEYVAVLRLHGMRPELDEAT---------------VRRAIETLTGPLYQRPPLISAVK 176
           A K Y  ++RL G+    D+A+               +  A+    G + Q PP  SAVK
Sbjct:  71 ALKCYRFMVRL-GLSTRTDDASGEVIATSEARPTDAEIEAALAAFRGEIQQVPPQFSAVK 129

Query: 177 RQ---------------LRIRTIY-ESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGL 220
            +               L  R ++ ES  +   P    V   + C  G Y+R++   LG 
Sbjct: 130 VEGERAYDLARDGERLDLAARPLWVESLEILSRPDADHVELEMVCGKGGYVRSIARDLGE 189

Query: 221 LLGVGGHMQELRRVRSGVHSEYDGM 245
            LG  GH+  LRR  SG     DG+
Sbjct: 190 ALGCHGHVAWLRRTWSGPFEAEDGI 214

emb|CAH13971.1| tRNA pseudouridine synthase B [Legionella pneumophila str. Paris]
ref|YP_125123.1| tRNA pseudouridine synthase B [Legionella pneumophila str. Paris]
sp|Q5X1C5|TRUB_LEGPA tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(303 aa)

Score: 75 bits (184), Expect: 2.83172e-12
Length: 260, Idn/Pos/Gap = 68/113/49 (26%/43%/18%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           G++ L+KP   +S+  +   K +   +K GH+G+LDP  TG L +C   AT++ +   +A
Sbjct:  12 GILLLNKPQGMTSNAALQKAKHLFGAKKAGHTGSLDPLATGMLPLCFGEATKICQYLLNA  71

Query: 133 GKEYVAVLRLHGMRPELDEAT----------------VRRAIETLTGPLYQRPPLISAVK 176
            K Y  + RL G +    + T                +   +E   G + Q P + SA+K
Sbjct:  72 DKSYETIGRL-GSKTNTADCTGEVIFCIENYTVSHEEMIATLEKYKGKIKQIPSMFSALK 130

Query: 177 -----------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLG 219
                            R+ R   I + KL ++D +       VSC  GTYIR L   +G
Sbjct: 131 HKGTPLYRLAREGIEIERKARDIVISQLKLEQFDGE--CFTLTVSCSKGTYIRNLVEDIG 188

Query: 220 LLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRV--IKPLESL 277
             L  G HM +L R+ +    E + M T+          D  +D    +R+  + P++  
Sbjct: 189 DTLKAGAHMTKLHRLYTAGF-ENNRMYTL----------DELQDMPLSQRLACLIPIDQA 237

Query: 278 LVHHKRIVIKDSCVNAVCYG 297
           + H   +++ DS V A+  G
Sbjct: 238 IQHLTPVILSDSEVTAIRQG 257

ref|NP_945787.1| putative tRNA pseudouridine 55 synthase [Rhodopseudomonas palustris CGA009]
emb|CAE25878.1| putative tRNA pseudouridine 55 synthase [Rhodopseudomonas palustris CGA009]
sp|P60345|TRUB_RHOPA tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(366 aa)

Score: 75 bits (184), Expect: 2.85544e-12
Length: 238, Idn/Pos/Gap = 74/103/37 (31%/43%/15%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           G + LDKP   +S + VA +KR+   ++ GH+GTLDP  +G L + +  AT+ V      
Sbjct:  57 GWVVLDKPIGMTSTQAVAVLKRLFSAKRAGHAGTLDPLASGGLPIAMGEATKTVPFVMDG 116

Query: 133 GKEYVAVL-------------RLHGMRPELDEATVRRA-IETLTGPLYQRPPLISAVKRQ 178
            K Y   +             R     P+   A   RA +   TG + Q PP  SAVK Q
Sbjct: 117 RKRYRFTVAWGEERDTDDTEGRAVATSPDRPTAEAIRALLPRFTGVIEQVPPQYSAVKIQ 176

Query: 179 -----------------LRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLL 221
                             R   I+E  L+E+    R V F   C  GTY+R L   +G L
Sbjct: 177 GERAYDLARDGEVVPLVPRPVEIHELTLVEHGDDGRSV-FEAECGKGTYVRALARDMGRL 235

Query: 222 LGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFD-TTKDESYLRRVIKPLESLL 278
           LG  GH+  LRR   G   E D M+ + ++   Q L D     E  L   + P+E+ L
Sbjct: 236 LGCYGHICALRRTVVGPFDESD-MIPLEEL---QALCDRAASGEGSLADALLPVETAL 289

sp|Q5ZRV6|TRUB_LEGPH tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(303 aa)

Score: 74 bits (182), Expect: 4.33367e-12
Length: 260, Idn/Pos/Gap = 67/113/49 (25%/43%/18%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           G++ L+KP   +S+  +   K +   +K GH+G+LDP  TG L +C   AT++ +   +A
Sbjct:  12 GILLLNKPQGMTSNAALQKTKHLFGAKKAGHTGSLDPLATGMLPLCFGEATKICQYLLNA  71

Query: 133 GKEYVAVLRLHGMRPELDEAT----------------VRRAIETLTGPLYQRPPLISAVK 176
            K Y  + RL G++    + T                +   +E   G + Q P + SA+K
Sbjct:  72 DKSYETIGRL-GIKTNTADCTGEVIFCIENYTVSHEEMIATLEKYKGKIKQIPSMFSALK 130

Query: 177 -----------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLG 219
                            R+ R   I +  L ++D +       VSC  GTYIR L   +G
Sbjct: 131 HKGTPLYRLAREGIEIERKARDIVISQLNLEQFDGE--CFTLTVSCSKGTYIRNLVEDIG 188

Query: 220 LLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRV--IKPLESL 277
             L  G HM +L R+ +    E + M T+          D  +D    +R+  + P++  
Sbjct: 189 DTLKAGAHMTKLHRLYTAGF-ENNRMYTL----------DELQDMPLSQRLACLIPIDQA 237

Query: 278 LVHHKRIVIKDSCVNAVCYG 297
           + H   +++ DS V A+  G
Sbjct: 238 VQHLTPVILSDSEVTAIRQG 257

ref|YP_096768.1| tRNA pseudouridine synthase B [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
gb|AAU28821.1| tRNA pseudouridine synthase B [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
(308 aa)

Score: 74 bits (182), Expect: 4.33367e-12
Length: 260, Idn/Pos/Gap = 67/113/49 (25%/43%/18%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           G++ L+KP   +S+  +   K +   +K GH+G+LDP  TG L +C   AT++ +   +A
Sbjct:  17 GILLLNKPQGMTSNAALQKTKHLFGAKKAGHTGSLDPLATGMLPLCFGEATKICQYLLNA  76

Query: 133 GKEYVAVLRLHGMRPELDEAT----------------VRRAIETLTGPLYQRPPLISAVK 176
            K Y  + RL G++    + T                +   +E   G + Q P + SA+K
Sbjct:  77 DKSYETIGRL-GIKTNTADCTGEVIFCIENYTVSHEEMIATLEKYKGKIKQIPSMFSALK 135

Query: 177 -----------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLG 219
                            R+ R   I +  L ++D +       VSC  GTYIR L   +G
Sbjct: 136 HKGTPLYRLAREGIEIERKARDIVISQLNLEQFDGE--CFTLTVSCSKGTYIRNLVEDIG 193

Query: 220 LLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRV--IKPLESL 277
             L  G HM +L R+ +    E + M T+          D  +D    +R+  + P++  
Sbjct: 194 DTLKAGAHMTKLHRLYTAGF-ENNRMYTL----------DELQDMPLSQRLACLIPIDQA 242

Query: 278 LVHHKRIVIKDSCVNAVCYG 297
           + H   +++ DS V A+  G
Sbjct: 243 VQHLTPVILSDSEVTAIRQG 262

ref|NP_341931.1| tRNA pseudouridine synthase subunit A (truB) [Sulfolobus solfataricus P2]
gb|AAK40721.1| tRNA pseudouridine synthase subunit A (truB) [Sulfolobus solfataricus P2]
pir||B99183 tRNA pseudouridine synthase subunit A (truB) [imported] - Sulfolobus solfataricus
(89 aa)

Score: 74 bits (182), Expect: 5.07814e-12
Length: 52, Idn/Pos/Gap = 30/40/0 (57%/76%/0%)

Query:  58 GYSPLKRPIQEYIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDP 109
           GY P KRPI+ +I++ +INLDKP  P+SHEV  W+K++L V K GH GTL+P
Sbjct:  33 GYYPEKRPIEIHIKNSIINLDKPPGPTSHEVAYWVKKMLNVTKAGHGGTLEP  84

ref|ZP_00151449.2| COG0130: Pseudouridine synthase [Dechloromonas aromatica RCB]
(278 aa)

Score: 74 bits (182), Expect: 5.38357e-12
Length: 185, Idn/Pos/Gap = 54/80/33 (29%/43%/17%)

Query:  84 SSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAGKEYVAVLRL- 142
           +S++ +   +R+    K GH+GTLDP  TG L +C   AT+       A K Y AVL+L 
Sbjct:   2 TSNDALQKARRLFSAAKGGHTGTLDPLATGLLPLCFGEATKFSADLLDADKTYEAVLKLG  61

Query: 143 -------------HGMRPELDEATVRRAIETLTGPLYQRPPLISAVK------------- 176
                             ++ +  V   +    G + Q PP+ SA+K             
Sbjct:  62 VTTDSGDAEGQVTSTAMVDIQKEQVSEVLPRFVGDIQQIPPMHSALKRNGRPLYELARQG 121

Query: 177 ----RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELR 232
               R+ R  TI+    L++     L+   V+C  GTYIR L   +G  LG G H+  LR
Sbjct: 122 IEVEREPRAVTIFAIDCLDFSGD--LLTLRVACSKGTYIRVLAADIGKALGCGAHLAALR 179

Query: 233 RVRSG 237
           R+  G
Sbjct: 180 RIVVG 184

gb|AAL53144.1| TRNA PSEUDOURIDINE SYNTHASE B [Brucella melitensis 16M]
ref|NP_540880.1| TRNA PSEUDOURIDINE SYNTHASE B [Brucella melitensis 16M]
sp|Q8YEB5|TRUB_BRUME tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(324 aa)

Score: 74 bits (182), Expect: 5.42868e-12
Length: 241, Idn/Pos/Gap = 78/106/41 (32%/43%/17%)

Query:  64 RPIQEYIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERAT 123
           RPI     SG +  DKP    S E V+ IK +   EK GH+GTLDP  +G L + +  AT
Sbjct:  10 RPI-----SGWVIFDKPKGMGSTEAVSKIKWLFSAEKAGHAGTLDPLASGMLPIALGEAT  64

Query: 124 RLVKSQQSAGKEYVAVLR---------LHGMRPEL-DEATVRRAIETL----TGPLYQRP 169
           + V       K Y   +          L G   +  D+   R  +E L    TG + Q P
Sbjct:  65 KTVPYAMDGTKVYRFTVTWGEERSTDDLEGQPTKTSDKRPSREEVEALLPDYTGVISQVP 124

Query: 170 PLISAVK----------RQLRIRTIYESKLLEYD-------PKRRLVLFWVSCEAGTYIR 212
           P  SA+K          R+     I  ++ +E D       P      F V C  GTY+R
Sbjct: 125 PQFSAIKIDGERAYDLAREGETVEI-PAREVEIDRLEIVGFPDADRTEFEVECSKGTYVR 183

Query: 213 TLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIK 272
           +L   +G  LG  GH+ +LRRV     ++ D MVT+   L+A W     KDE     VI+
Sbjct: 184 SLARDMGRDLGCYGHISDLRRVEVAPFTDED-MVTLAK-LEAVWPPLPPKDED--GNVIE 239

Query: 273 P 273
           P
Sbjct: 240 P 240

ref|YP_009728.1| tRNA pseudouridine synthase B [Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough]
sp|Q72ER4|TRUB_DESVH tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
gb|AAS94987.1| tRNA pseudouridine synthase B [Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough]
(304 aa)

Score: 73 bits (180), Expect: 7.3307e-12
Length: 200, Idn/Pos/Gap = 65/94/35 (32%/47%/17%)

Query:  65 PIQEYIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATR 124
           P+Q++   G++ LDKP+ PSS + ++ +KR L  +K GH+GTLDP   G L+V +  AT+
Sbjct:   2 PVQQH---GLLVLDKPSGPSSAQCISKVKR-LGQKKIGHAGTLDPMAGGVLLVLLGHATK  57

Query: 125 LVKSQQSAG-KEYVAVLRLHGMRPELD---------------EATVRRAIETLTGPLYQR 168
           +     + G K Y   LRL       D               EA VR  +++  G   Q 
Sbjct:  58 ISGHLMADGEKVYAGTLRLGETTDTWDAEGTVTATAPWHHVTEADVRAIVDSWLGSSEQE 117

Query: 169 PPLISAVKRQLRI---------RTIYESKLLEYDPKRRL------VLFWVSCEAGTYIRT 213
            P  SA K Q +           T  ++K +E      +      V F V C +GTYIR+
Sbjct: 118 VPPYSAAKHQGQPLYKLSRAGRETPVKTKTVEISLAEVVWCDLPHVRFRVRCSSGTYIRS 177

Query: 214 LCVHLGLLLGVGGHMQELRR 233
           L   LG+ LG G  + EL R
Sbjct: 178 LAHSLGIRLGCGAVLTELTR 197

ref|YP_222797.1| tRNA pseudouridine synthase B [Brucella abortus biovar 1 str. 9-941]
gb|AAX75436.1| tRNA pseudouridine synthase B [Brucella abortus biovar 1 str. 9-941]
gb|AAT34907.1| tRNA pseudouridine synthase B [Brucella suis 1330]
sp|P59876|TRUB_BRUSU tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
ref|YP_089635.1| tRNA pseudouridine synthase B [Brucella suis 1330]
(324 aa)

Score: 73 bits (180), Expect: 8.30806e-12
Length: 241, Idn/Pos/Gap = 78/106/41 (32%/43%/17%)

Query:  64 RPIQEYIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERAT 123
           RPI     SG +  DKP    S E V+ IK +   EK GH+GTLDP  +G L + +  AT
Sbjct:  10 RPI-----SGWVIFDKPKGMGSTEAVSKIKWLFSAEKAGHAGTLDPLASGMLPIALGEAT  64

Query: 124 RLVKSQQSAGKEYVAVLR---------LHGMRPEL-DEATVRRAIETL----TGPLYQRP 169
           + V       K Y   +          L G   +  D+   R  +E L    TG + Q P
Sbjct:  65 KTVPYVMDGTKVYRFTVTWGEERSTDDLEGQPTKTSDKRPSREEVEALLPDYTGVISQVP 124

Query: 170 PLISAVK----------RQLRIRTIYESKLLEYD-------PKRRLVLFWVSCEAGTYIR 212
           P  SA+K          R+     I  ++ +E D       P      F V C  GTY+R
Sbjct: 125 PQFSAIKIDGERAYDLAREGETVEI-PAREVEIDRLEIVGFPDADRTEFEVECSKGTYVR 183

Query: 213 TLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIK 272
           +L   +G  LG  GH+ +LRRV     ++ D MVT+   L+A W     KDE     VI+
Sbjct: 184 SLARDMGRDLGCYGHISDLRRVEVAPFTDED-MVTLAK-LEAVWPPLPPKDED--GNVIE 239

Query: 273 P 273
           P
Sbjct: 240 P 240

emb|CAH16928.1| tRNA pseudouridine synthase B [Legionella pneumophila str. Lens]
ref|YP_128015.1| tRNA pseudouridine synthase B [Legionella pneumophila str. Lens]
sp|Q5WT38|TRUB_LEGPL tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(303 aa)

Score: 73 bits (180), Expect: 8.37767e-12
Length: 260, Idn/Pos/Gap = 68/112/49 (26%/43%/18%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           G++ L+KP   +S+  +   K +   +K GH+G+LDP  TG L +C   AT++ +   +A
Sbjct:  12 GILLLNKPQGMTSNAALQKAKHLFGAKKAGHTGSLDPLATGMLPLCFGEATKICQYLLNA  71

Query: 133 GKEYVAVLRLHGMRPELDEAT----------------VRRAIETLTGPLYQRPPLISAVK 176
            K Y  + RL G +    + T                +   +E   G   Q P + SA+K
Sbjct:  72 DKSYETIGRL-GSKTNTADCTGEVIFCIENYTVSHEELIATLEKYKGKTKQIPSMFSALK 130

Query: 177 -----------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLG 219
                            R+ R   I + KL ++D +       VSC  GTYIR L   +G
Sbjct: 131 HKGTPLYRLAREGIEIERKARDIVISQLKLEQFDGE--CFTLTVSCSKGTYIRNLVEDIG 188

Query: 220 LLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRV--IKPLESL 277
             L  G HM +L R+ +    E + M T+          D  +D    +R+  + P++  
Sbjct: 189 DTLKAGAHMTKLHRLYTAGF-ENNRMYTL----------DELQDMPLSQRLACLIPIDQA 237

Query: 278 LVHHKRIVIKDSCVNAVCYG 297
           + H   +++ DS V A+  G
Sbjct: 238 VQHLTPVILSDSEVTAIRQG 257

ref|ZP_00051647.2| COG0130: Pseudouridine synthase [Magnetospirillum magnetotacticum MS-1]
(341 aa)

Score: 73 bits (180), Expect: 8.80776e-12
Length: 202, Idn/Pos/Gap = 60/88/35 (29%/43%/17%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           SG + LDK    +S + VA +KR+   +K GH+GTLDP  +G L + +  AT+ V     
Sbjct:  49 SGWVVLDKGVGMTSTQAVAVVKRLFNAKKAGHAGTLDPLASGILPIALGEATKTVPFVMD 108

Query: 132 AGKEYVAVLRLHGMRPELDEA---------------TVRRAIETLTGPLYQRPPLISAVK 176
             K Y   +   G+  + D+A                V  A+ +  G + Q PP  SA+K
Sbjct: 109 GRKAYRFEVTW-GIETDTDDAEGRPIATSDVRPTREAVEAALPSFVGEIEQVPPRFSAIK 167

Query: 177 RQ-----------------LRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLG 219
            Q                  R   I    ++E++  R ++     C  GTY+R L   LG
Sbjct: 168 IQGERAYDLARDGEVVELVARAVRIDHLSVIEHEGDRTVLA--AECGKGTYVRALARDLG 225

Query: 220 LLLGVGGHMQELRRVRSGVHSE 241
            +LG  GH+  LRR R G   E
Sbjct: 226 RMLGCYGHVSALRRTRVGPFEE 247

sp|Q8D2X8|TRUB_WIGBR tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
dbj|BAC24370.1| truB [Wigglesworthia glossinidia endosymbiont of Glossina brevipalpis]
ref|NP_871227.1| hypothetical protein WGLp224 [Wigglesworthia glossinidia endosymbiont of Glossina brevipalpis]
(327 aa)

Score: 73 bits (180), Expect: 9.25992e-12
Length: 271, Idn/Pos/Gap = 67/127/46 (24%/46%/16%)

Query:  67 QEYIRS--GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATR 124
           ++Y+R+  G++ LDKP   SS+ ++  IK++ + +K G+ GTLDP  +G L +    AT+
Sbjct:  26 EDYLRNINGILLLDKPIGLSSNLILQKIKKLFKAKKAGYIGTLDPIASGMLPIFFGDATK  85

Query: 125 LVKSQQSAGKEYVAVLRLHG-------------MRPELD--EATVRRAIETLTGPLYQRP 169
                 +  K Y    +L               +RP L+  +  + + +    G +YQ+P
Sbjct:  86 FSDYLLNTNKWYKIKAKLGEKTNTLDSFGKIICIRPILNIKKLNIEKILSEFQGEIYQKP 145

Query: 170 PLISAVK-----------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIR 212
           P+ S++K                 R+ R   ++  KLL +   ++     + C  GTY+R
Sbjct: 146 PMFSSLKHLGKPLYKYARQGIYIPREKRKVYVHYIKLLSF--SKKYFSLTIKCSKGTYVR 203

Query: 213 TLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRV-- 270
           ++   +G  L  G H+ +LRR +   + E         ++D+  L++  K  + L+++  
Sbjct: 204 SIVDDIGEKLFCGAHIVKLRRTKLFNYKE-------SHMIDSNKLYNIKKKFNDLKKLDE 256

Query: 271 -IKPLESLLVHHKRIVIKDSCVNAVCYGAKL 300
            + P+ES+      IV+ D  +N +  G KL
Sbjct: 257 CLLPIESIFKKLPIIVVNDDIINRLRNGIKL 287

ref|ZP_00193745.2| COG0130: Pseudouridine synthase [Mesorhizobium sp. BNC1]
(312 aa)

Score: 73 bits (179), Expect: 1.09416e-11
Length: 264, Idn/Pos/Gap = 74/111/32 (28%/42%/12%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           SG + LDKPA   S E V+ +K +   +K GH+GTLDP  +G L + +  AT+ V     
Sbjct:  13 SGWLVLDKPAGLGSTEAVSKVKWLFGAQKAGHAGTLDPLASGMLPIALGEATKTVPYVME  72

Query: 132 AGKEYVAVLRLHGMRPELD--------------EATVRRAIETLTGPLYQRPPLISAVK- 176
             K Y   +     R   D              E  +R  +   TG + Q PP  SAVK 
Sbjct:  73 GAKVYRFTVAWGEERSTDDLEGPVTKSCDKVPVEEDIRALLPRYTGLIMQTPPQFSAVKI 132

Query: 177 --------------RQLRIRTIYESKL-LEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLL 221
                          ++  R +   +L L   P+ +  +F V C  GTY+R+L   +G  
Sbjct: 133 GGERAYDLAREGEVVEIAAREVEIGRLDLISIPEPKKAVFEVECGKGTYVRSLARDMGRD 192

Query: 222 LGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDE-SYLRRVIKPLESLLVH 280
           LG  GH+ +LRR       E   +V + D+  A    +T  D  S L   +   E+ L  
Sbjct: 193 LGCFGHVADLRRTEV-YPFETQQLVPLKDLEGAAADAETESDRFSALDSYLLDTEAALDG 251

Query: 281 HKRIVIKDSCVNAVCYGAKLMLPG 304
              IV+ D     +  G  +++ G
Sbjct: 252 LPEIVLGDDAAGRIRLGNPVIVRG 275

ref|NP_418856.1| tRNA pseudouridine synthase B [Caulobacter crescentus CB15]
gb|AAK22024.1| tRNA pseudouridine synthase B [Caulobacter crescentus CB15]
sp|P58063|TRUB_CAUCR tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(310 aa)

Score: 73 bits (178), Expect: 1.52766e-11
Length: 203, Idn/Pos/Gap = 61/89/36 (30%/43%/17%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           SG + LDKP + +S   V+ ++R    +K GH+GTLDP  TG L + +  AT+ V     
Sbjct:  11 SGWLCLDKPYDLTSTTAVSRVRRAFNAQKGGHAGTLDPLATGILPIALGEATKTVPFLMD  70

Query: 132 AGKEY---------VAVLRLHG-------MRPELDEATVRRAIETLTGPLYQRPPLISAV 175
           A K Y            L   G       +RP  ++  V  A+    G + Q PP  SA+
Sbjct:  71 ADKAYRFTIAWGRDTTTLDREGETTGTSDVRPTREQ--VEAALPAFIGEVDQIPPNFSAI 128

Query: 176 KRQ-----------------LRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHL 218
           K                    R  +I++ K+++  P    V   + C  GTY+R +   L
Sbjct: 129 KVDGERAYDLARDGVEFELPTRKVSIFDLKVVD-QPDADHVTLTMECGKGTYVRAVVRDL 187

Query: 219 GLLLGVGGHMQELRRVRSGVHSE 241
              LG  GH+ +LRR R G  SE
Sbjct: 188 AKALGTCGHVADLRRTRVGGFSE 210

ref|NP_968436.1| tRNA pseudouridine synthase B [Bdellovibrio bacteriovorus HD100]
emb|CAE79429.1| tRNA pseudouridine synthase B [Bdellovibrio bacteriovorus HD100]
sp|Q6MMS4|TRUB_BDEBA tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(308 aa)

Score: 72 bits (177), Expect: 1.68853e-11
Length: 250, Idn/Pos/Gap = 73/106/46 (29%/42%/18%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           +G++ +DKP+  SSH+VVA ++RIL     GHSGTLDP  +G +   +   T+L +    
Sbjct:   8 NGLLLVDKPSGISSHDVVARLRRILSTRAVGHSGTLDPMASGLMACLVNEGTKLSQYILE  67

Query: 132 AGKEYVAVLRLH-GMRPE-LDEATVRRAIET-----------------LTGPLYQRPPLI 172
             K Y   LR   G+R + LD  T    +ET                 L G +    P+ 
Sbjct:  68 GDKGY--RLRAQFGIRTDTLD--TTGETLETRPTDHLTRELILSEALKLQGEMEVEVPIY 123

Query: 173 SAVKRQLRIRTIYESKLLEYDPKRRLVLFW---------------VSCEAGTYIRTLCVH 217
           SA+K Q +    Y     E    ++++ FW               + C  G+YIRT    
Sbjct: 124 SAIKVQGKKLYEYARGEQEVTIPKKVMKFWDIEPVEIGSDWAEFDIKCSKGSYIRTWIDL 183

Query: 218 LGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPLESL 277
           LG  LG G  M  LRR  S  + + D   T+  +       + +     L     P+E  
Sbjct: 184 LGKALGCGAAMSGLRRTWSSPY-KIDQAQTLEQI-------EASVKGGSLGPAFVPMELA 235

Query: 278 LVHHKRIVIK 287
           L   KRI IK
Sbjct: 236 LPQVKRIRIK 245

ref|NP_758311.1| tRNA pseudouridine 5S synthase [Mycoplasma penetrans HF-2]
sp|Q8CXQ2|TRUB_MYCPE tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
dbj|BAC44715.1| tRNA pseudouridine 5S synthase [Mycoplasma penetrans HF-2]
(232 aa)

Score: 72 bits (176), Expect: 2.41728e-11
Length: 202, Idn/Pos/Gap = 53/92/36 (26%/45%/17%)

Query:  70 IRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQ 129
           ++  +  ++KP N SS++V+  IK+   ++K GH+GTLDP  TG L+V     T+ +   
Sbjct:  15 LKDKIFGINKPKNFSSNQVIQIIKKYYGLKKIGHAGTLDPLATGLLLVATNSKTKELNEL  74

Query: 130 QSAGKEYVAVLRLHGMRPELD--------------EATVRRAIETLTGPL-YQRPPLISA 174
               K+YVA ++ +      D              E T++  ++ L     YQ+PP+ SA
Sbjct:  75 ILENKKYVAEIQFNYQTSTYDAEGEITNYTTRKIHEKTLKEELKFLNSTYWYQQPPVYSA 134

Query: 175 VKRQLRIRTIYE-------------------SKLLEYDPKRRLVLFWVSCEAGTYIRTLC 215
           VK  ++ + +YE                    +L+ +D   +     +    G YIR+  
Sbjct: 135 VK--IKGKKLYEYARANQEVSVPFKKVYINKVELISFDSISQKTFVSLDVSKGFYIRSFA 192

Query: 216 VHLGLLLGVGGHMQELRRVRSG 237
             +GL L   G++  L+RV  G
Sbjct: 193 NDIGLRLNNYGYLLNLKRVEVG 214

ref|NP_147651.1| nucleolar protein [Aeropyrum pernix K1]
dbj|BAA79973.1| 107aa long hypothetical nucleolar protein [Aeropyrum pernix K1]
pir||E72696 probable nucleolar protein APE0989 - Aeropyrum pernix  (strain K1)
(107 aa)

Score: 71 bits (174), Expect: 4.26318e-11
Length: 55, Idn/Pos/Gap = 32/41/0 (58%/74%/0%)

Query:  55 PDAGYSPLKRPIQEYIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDP 109
           P  GY P +RP+  Y+R G+I +DKP  P+SHEVVAWIKR+L V + GH GTL+P
Sbjct:  39 PRYGYLPHERPLDVYLRYGMIVVDKPPGPTSHEVVAWIKRMLGVSRAGHGGTLEP  93

ref|NP_082391.1| TruB pseudouridine (psi) synthase homolog 1 [Mus musculus]
dbj|BAC27506.1| unnamed protein product [Mus musculus]
(338 aa)

Score: 70 bits (170), Expect: 1.08538e-10
Length: 235, Idn/Pos/Gap = 65/98/52 (27%/41%/22%)

Query:  72 SGVINLDKPANPSSHEVV----------------AWIKRILRVEKTGHSGTLDPQVTGCL 115
           SGV  + KP  P+S E++                 W KR  +  K GH GTLD    G L
Sbjct:  57 SGVFAVHKPKGPTSAELLNRLKEKLLAEAGMPSPEWNKRQKQTLKVGHGGTLDSAAQGVL 116

Query: 116 IVCIERATRLVKSQQSAGKEYVAVLRLHGMRPELD-----------EATVRRAIETL--- 161
           +V I R T+++ S  S  K Y+ +  L      LD           +   R  IE +   
Sbjct: 117 VVGIGRGTKMLTSMLSGSKRYITIGELGKATDTLDSTGKVTEEKPYDKITREDIEGILQK 176

Query: 162 -TGPLYQRPPLISAVKRQ-LRIRTIYES-KLLEYDPKRRLVLFWVS-------------- 204
            TG + Q PPL SA+K+   R+ T+ +  K++E  P R + +  +S              
Sbjct: 177 FTGNIMQVPPLYSALKKDGQRLSTLMKKGKVVEARPARPVTVHSISLLKFQPPFFTLDVE 236

Query: 205 CEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFD 259
           C  G YIR+L   +G  L     + EL R + G  +     +  H + + +W  D
Sbjct: 237 CGGGFYIRSLVSDIGKELSSCASVLELTRTKQGPFT-----LAQHALPEDRWTID 286

emb|CAA63512.1| hypothetical protein [Lactococcus lactis]
(177 aa)

Score: 70 bits (170), Expect: 1.11289e-10
Length: 131, Idn/Pos/Gap = 44/70/18 (33%/53%/13%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           +G++N+ K A  +S +VVA ++ IL+ +K GH GTLDPQVTG L V + +ATRL++  + 
Sbjct:   2 NGILNVYKEAGWTSFDVVAKLRGILKTKKIGHGGTLDPQVTGVLPVAVGKATRLLEYMEE  61

Query: 132 AGKEYVA----------------VLRLHGMRPELDEATVRRAIETLTGPLYQRPPLISAV 175
           AGK Y                  V+    +   L +  +   +    G + Q PP+ SAV
Sbjct:  62 AGKVYEGEVTIGFSTETEDAEGEVIETTPVPSTLSDEEIDEVMTRFVGEIQQVPPMYSAV 121

Query: 176 KRQLRIRTIYE 186
           K  ++ + +YE
Sbjct: 122 K--VKGKRLYE 130

ref|ZP_00143641.1| tRNA pseudouridine synthase B [Fusobacterium nucleatum subsp. vincentii ATCC 49256]
gb|EAA24747.1| tRNA pseudouridine synthase B [Fusobacterium nucleatum subsp. vincentii ATCC 49256]
(287 aa)

Score: 70 bits (170), Expect: 1.25079e-10
Length: 199, Idn/Pos/Gap = 58/97/33 (29%/48%/16%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           G+I ++KP   +S +V+  +K+IL+ +K GH+GTLDP  TG ++VC+ +AT+L    ++ 
Sbjct:   3 GIIVVNKPKGITSFDVIRKLKKILKTKKIGHTGTLDPLATGVMLVCVGKATKLASDLEAK  62

Query: 133 GKEYVA---------VLRLHGMR-----PELDEATVRRAIETLTGPLYQRPPLISAVK-- 176
            K Y+A            + G +      E+ +  + ++I+   G + Q PP+ SA+K  
Sbjct:  63 NKIYIADFDIGYATDTYDVEGKKIAENIIEVSKENLEQSIKKFIGNIKQVPPMYSAIKID 122

Query: 177 ---------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLL 221
                          R  R  TI    LL++   +  +   VS   G YIR+L   +G  
Sbjct: 123 GNKLYHLARKGIEVERPKRDVTIEYINLLDFKNNKAKIETEVS--KGCYIRSLIYDIGQD 180

Query: 222 LGVGGHMQELRRVRSGVHS 240
           LG    M  L+R + G +S
Sbjct: 181 LGTYATMTALQRKQVGEYS 199

ref|XP_574696.1| PREDICTED: TruB pseudouridine (psi) synthase homolog 1 (E. coli) (predicted) [Rattus norvegicus]
ref|NP_001012173.1| TruB pseudouridine (psi) synthase homolog 1 (E. coli) (predicted) [Rattus norvegicus]
gb|AAH87683.1| TruB pseudouridine (psi) synthase homolog 1 (E. coli) (predicted) [Rattus norvegicus]
(341 aa)

Score: 70 bits (170), Expect: 1.32602e-10
Length: 215, Idn/Pos/Gap = 61/84/51 (28%/39%/23%)

Query:  72 SGVINLDKPANPSSHEVV----------------AWIKRILRVEKTGHSGTLDPQVTGCL 115
           SGV  + KP  P+S E++                 W KR  +  K GH GTLD    G L
Sbjct:  60 SGVFAVHKPKGPTSAELLNRLKEKLLAEAGLPSPEWNKRQKQTLKVGHGGTLDSAAQGVL 119

Query: 116 IVCIERATRLVKSQQSAGKEYVAVLRLHGMRPELD---------------EATVRRAIET 160
           +V I R T+++ S  S  K Y+A   L      LD               +  +   ++ 
Sbjct: 120 VVGIGRGTKMLTSMLSGSKRYIATGELGKATDTLDSTGKVTEEKPYDKITQEDIEGILQK 179

Query: 161 LTGPLYQRPPLISAVK------------------RQLRIRTIYESKLLEYDPKRRLVLFW 202
            TG + Q PPL SA+K                  R  R  T++   LL+Y P        
Sbjct: 180 FTGNIMQVPPLYSALKKDGQRLSTLMKRGETVEARPARPVTVHSISLLKYQPP--FFTLD 237

Query: 203 VSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSG 237
           V C  G YIR+L   +G  L     + EL R + G
Sbjct: 238 VECGGGFYIRSLVSDIGKELSSCATVLELTRTKQG 272

ref|ZP_00128962.2| COG0130: Pseudouridine synthase [Desulfovibrio desulfuricans G20]
(309 aa)

Score: 69 bits (169), Expect: 1.38251e-10
Length: 245, Idn/Pos/Gap = 71/105/42 (28%/42%/17%)

Query:  71 RSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQ 130
           + GV+ L+KP  P+S   +A IKR L  +K GH+GTLDP   G L+V + + T++     
Sbjct:   9 QHGVLVLNKPKGPTSAHCIARIKR-LGQKKIGHAGTLDPMAQGVLLVLLGQCTKISGYLM  67

Query: 131 SAGKE-YVAVLRLHGMRPELD---------------EATVRRAIETLTGPLYQRPPLISA 174
             G++ Y   L L       D               E  V RA++  TG   Q+ P  SA
Sbjct:  68 EGGEKIYSGTLELGRTTDTWDDEGETLSTADWTHVTEEDVVRAVDLWTGSSEQQVPAYSA 127

Query: 175 VKRQ---------------LRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLG 219
            K +               ++ R I  S+      +   V F V C +GTYIR+L   LG
Sbjct: 128 AKHKGQPLYKLAREGKETPVKTRRIEISQAETLAVELPFVRFRVHCSSGTYIRSLAHSLG 187

Query: 220 LLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFDTTKDESYLRRVIKPLESLLV 279
             LG G  + EL R       EY    ++ +  D   L D   + + L   + PL+  L 
Sbjct: 188 NRLGCGAVLTELIR-------EYSHPFSLDEAHD---LDDVLAEPAELAGRVIPLDKALP 237

Query: 280 HHKRI 284
           H  ++
Sbjct: 238 HWPKL 242

gb|AAP56469.1| TruB [Mycoplasma gallisepticum R]
ref|NP_852901.1| TruB [Mycoplasma gallisepticum R]
sp|P59879|TRUB_MYCGA tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(218 aa)

Score: 69 bits (169), Expect: 1.38251e-10
Length: 215, Idn/Pos/Gap = 59/93/41 (27%/43%/19%)

Query:  74 VINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAG 133
           ++ +DKP N SS   +   K+   ++K GH+GTLDP  +G L+V   + T+ +       
Sbjct:  11 IVIIDKPKNISSAFCLNLFKKRFNIKKAGHNGTLDPLASGVLVVATNKRTKELSQLNQDD  70

Query: 134 KEYVAVLRLHGMRPELDE-----------ATVRRAIETLTG----PLYQRPPLISAVK-- 176
           K+Y+  L+ +      D              +++  + LT       YQ PP  SA+K  
Sbjct:  71 KQYLVKLKFNTHTDSYDRLGKVIRTTNYVPEIKQLNDYLTSLDNHSFYQLPPNFSALKVN 130

Query: 177 ----RQL-----------RIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLL 221
                QL           R  TIY++KL+ Y      +L  V  + G Y+R+  V L   
Sbjct: 131 GVRAYQLARKAVDFELEKRPTTIYKAKLISYYDDYAEILLDV--KKGFYVRSFVVDLASQ 188

Query: 222 LGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQW 256
                 M +L R RSG +S       + DV+D Q+
Sbjct: 189 FNTTAMMVDLVRTRSGQYS-------LKDVIDYQF 216

ref|NP_767421.1| tRNA pseudouridine 55 synthase [Bradyrhizobium japonicum USDA 110]
sp|Q89WB1|TRUB_BRAJA tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
dbj|BAC46046.1| tRNA pseudouridine 55 synthase [Bradyrhizobium japonicum USDA 110]
(345 aa)

Score: 69 bits (168), Expect: 2.01248e-10
Length: 290, Idn/Pos/Gap = 85/121/40 (29%/41%/13%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           G + LDKP   +S + VA +KR+   ++ GH+GTLDP  +G L + +  AT+ V      
Sbjct:  37 GWVVLDKPIGMTSTQAVAVLKRLFNAKRAGHAGTLDPLASGGLPIALGEATKTVPFVMDG  96

Query: 133 GKEYVAVLRLHGMRPELD-EATV---------RRAIETL----TGPLYQRPPLISAVKRQ 178
            K Y   +     R   D E  V         R AI  L    TG + Q PP  SA+K Q
Sbjct:  97 RKRYQFTVCWGEERDTDDIEGRVTATSELRPTREAILALLPRFTGVIEQIPPRYSAIKIQ 156

Query: 179 ---------------LRIRTIYESKLLEYD-PKRRLVLFWVSCEAGTYIRTLCVHLGLLL 222
                          L  R +   +L   D P     +F   C  GTY+R L   +G +L
Sbjct: 157 GERAYDLARDGEVVELAPRPVEIHRLTLVDQPDNDRAVFEAECGKGTYVRALARDMGRIL 216

Query: 223 GVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFD-TTKDESYLRRVIKPLESLLVHH 281
           G  GH+  LRR   G   E D M+ + D L+A  L D     E  L   + P+E+ L   
Sbjct: 217 GTYGHICALRRTLVGPFGEND-MIPL-DQLEA--LCDRAASGEGSLADALLPVETALDDI 272

Query: 282 KRIVIKDSCVNAVCYGAKLMLPGVLRYENDIECGEEVVIMTTKGEAVALA 331
             + +  +    +  G  ++L G      D       V +T  G  +ALA
Sbjct: 273 PALAVTRADAARLHRGQAVLLRG-----RDAPTCSGTVYVTVAGRLLALA 317

dbj|BAD97287.1| TruB pseudouridine (psi) synthase homolog 1 variant [Homo sapiens]
(349 aa)

Score: 69 bits (168), Expect: 2.13352e-10
Length: 213, Idn/Pos/Gap = 58/90/47 (27%/42%/22%)

Query:  72 SGVINLDKPANPSSHEVV----------------AWIKRILRVEKTGHSGTLDPQVTGCL 115
           SGV  + KP  P+S E++                 W KR  +  K GH GTLD    G L
Sbjct:  69 SGVFAVHKPKGPTSAELLNRLKEKLLAEAGMPSPEWTKRKKQTLKIGHGGTLDSAARGVL 128

Query: 116 IVCIERATRLVKSQQSAGKEYVAVLRLHGMRPELD---------------EATVRRAIET 160
           +V I   T+++ S  S  K Y A+  L      LD               +  +   ++ 
Sbjct: 129 VVGIGSGTKMLTSMLSGSKRYTAIGELGKATDTLDSTGRVTEEKPYDKITQEDIEGILQK 188

Query: 161 LTGPLYQRPPLISAVKRQ-LRIRTIYE-SKLLEYDPKRRLVLFWVS-------------- 204
            TG + Q PPL SA+K+   R+ T+ +  +++E  P R + ++ +S              
Sbjct: 189 FTGNIMQVPPLYSALKKDGQRLSTLMKRGEVVEAKPARPVTVYSISLQKFQPPFFTLDVE 248

Query: 205 CEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSG 237
           C  G YIR+L   +G  L    ++ EL R + G
Sbjct: 249 CGGGFYIRSLVSDIGKELSSCANVLELTRTKQG 281

emb|CAH10560.1| hypothetical protein [Homo sapiens]
emb|CAH73219.1| TruB pseudouridine (psi) synthase homolog 1 (E. coli) [Homo sapiens]
gb|AAH30601.1| TruB pseudouridine (psi) synthase homolog 1 [Homo sapiens]
gb|AAL40350.1| TruB pseudouridine synthase-like protein 1 [Homo sapiens]
ref|NP_631908.1| TruB pseudouridine (psi) synthase homolog 1 [Homo sapiens]
(349 aa)

Score: 69 bits (168), Expect: 2.24305e-10
Length: 235, Idn/Pos/Gap = 61/98/52 (25%/41%/22%)

Query:  72 SGVINLDKPANPSSHEVV----------------AWIKRILRVEKTGHSGTLDPQVTGCL 115
           SGV  + KP  P+S E++                 W KR  +  K GH GTLD    G L
Sbjct:  69 SGVFAVHKPKGPTSAELLNRLKEKLLAEAGMPSPEWTKRKKQTLKIGHGGTLDSAARGVL 128

Query: 116 IVCIERATRLVKSQQSAGKEYVAVLRLHGMRPELD---------------EATVRRAIET 160
           +V I   T+++ S  S  K Y A+  L      LD               +  +   ++ 
Sbjct: 129 VVGIGSGTKMLTSMLSGSKRYTAIGELGKATDTLDSTGRVTEEKPYDKITQEDIEGILQK 188

Query: 161 LTGPLYQRPPLISAVKRQ-LRIRTIYE-SKLLEYDPKRRLVLFWVS-------------- 204
            TG + Q PPL SA+K+   R+ T+ +  +++E  P R + ++ +S              
Sbjct: 189 FTGNIMQVPPLYSALKKDGQRLSTLMKRGEVVEAKPARPVTVYSISLQKFQPPFFTLDVE 248

Query: 205 CEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFD 259
           C  G YIR+L   +G  L    ++ EL R + G  +     +  H + + +W  D
Sbjct: 249 CGGGFYIRSLVSDIGKELSSCANVLELTRTKQGPFT-----LEEHALPEDKWTID 298

ref|NP_326381.1| TRNA PSEUDOURIDINE SYNTHASE B (TRNA PSEUDOURIDINE 55 SYNTHASE) (PSI55 SYNTHASE) (PSEUDOURIDYLATE SYNTHASE) (URACIL HYDROLYASE) [Mycoplasma pulmonis UAB CTIP]
emb|CAC13723.1| TRNA PSEUDOURIDINE SYNTHASE B (TRNA PSEUDOURIDINE 55 SYNTHASE) (PSI55 SYNTHASE) (PSEUDOURIDYLATE SYNTHASE) (URACIL HYDROLYASE) [Mycoplasma pulmonis]
sp|Q98Q19|TRUB_MYCPU tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(282 aa)

Score: 68 bits (167), Expect: 2.50004e-10
Length: 195, Idn/Pos/Gap = 57/92/40 (29%/47%/20%)

Query:  98 VEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAGKEYVAVLRLHGMRPE--------- 148
           ++K GHSGTLDP+ TG L++  +  T+L+       K Y A + L G++ +         
Sbjct:  26 IKKIGHSGTLDPEATGLLLLASDEDTKLLDYVDKKFKSYRATMIL-GLQSQSFDSQGKII  84

Query: 149 ------LDEATVRRAIETLTGPLYQRPPLISAVK----------RQ-----LRIRTIYES 187
                 +D  T+ + I+   GP  Q PP+ SA K          RQ     ++ + ++  
Sbjct:  85 NSSNLKVDNLTIEKTIKNFVGPFVQIPPIFSAKKINGKRAYEYARQGSEISMKAQEVF-V 143

Query: 188 KLLEYD----PKRRLVLFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVR-SGVHSEY 242
           K +E +    PK   V+F      GTYIR+L   +GL L     M +L R+  SG+    
Sbjct: 144 KSIEIEKIDFPK---VIFKAKVSRGTYIRSLINQIGLELKTYALMDDLERIELSGLSKND 200

Query: 243 DGMVTMHDVLDAQWL 257
            G+V+  D++D + L
Sbjct: 201 LGVVSDLDIIDLEVL 215

ref|NP_376275.1| hypothetical centromere/microtubule binding protein cbf5 [Sulfolobus tokodaii str. 7]
dbj|BAB65384.1| 84aa long hypothetical centromere/microtubule binding protein cbf5 [Sulfolobus tokodaii str. 7]
(84 aa)

Score: 68 bits (167), Expect: 2.8571e-10
Length: 52, Idn/Pos/Gap = 28/37/0 (53%/71%/0%)

Query:  58 GYSPLKRPIQEYIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDP 109
           GY   KRPI+  I++ +IN DKP  P+SHEV  WIK++ +V K GH GTL+P
Sbjct:  33 GYFADKRPIEVLIKNSIINADKPPGPTSHEVAYWIKQMFKVSKAGHGGTLEP  84

ref|XP_421776.1| PREDICTED: similar to TruB pseudouridine (psi) synthase homolog 1 [Gallus gallus]
(283 aa)

Score: 68 bits (167), Expect: 2.8571e-10
Length: 212, Idn/Pos/Gap = 59/93/46 (27%/43%/21%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVE---------------KTGHSGTLDPQVTGCLI 116
           SG+  + KP  P+S  V+  +K  L  E               K GH GTLD   TG L+
Sbjct:  18 SGLFAVYKPKGPTSAAVLNLLKERLLAEAGVQTKDKKRKRQALKIGHGGTLDSAATGVLV  77

Query: 117 VCIERATRLVKSQQSAGKEYVAVLRLHGMRPELD---------------EATVRRAIETL 161
           V I + T+L+K+  +  K+Y A+  L      LD               ++ +   ++  
Sbjct:  78 VGIGKGTKLLKTILAGSKKYTAIGLLGRATDTLDATGKVTEEKPYDQVTKSDLENVLQKF 137

Query: 162 TGPLYQRPPLISAVKRQ-LRIRTIYE-SKLLEYDPKRRLVLFWVS--------------C 205
           TG + Q PPL SA+KR   R+ T+ +  + +E  P R + ++ +S              C
Sbjct: 138 TGDIMQVPPLYSALKRDGERLSTLMKRGEAVEAKPARPVRVYSLSLRQFQPPLFTLDVEC 197

Query: 206 EAGTYIRTLCVHLGLLLGVGGHMQELRRVRSG 237
             G Y+R+L   +G  L     +QEL R + G
Sbjct: 198 GGGFYVRSLVSDIGKELSTCASIQELTRTKHG 229

gb|AAM82680.1| tRNA pseudoridine 55 synthase [Synechococcus sp. PCC 7942]
sp|Q8KIY0|TRUB_SYNP7 tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(294 aa)

Score: 68 bits (166), Expect: 3.34791e-10
Length: 122, Idn/Pos/Gap = 51/69/18 (41%/56%/14%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           G +NLDKPA  +SH+ VA ++R+LR  + GH GTLDP VTG L + + RATRL+    S 
Sbjct:   5 GFVNLDKPAGWTSHDCVAKLRRLLRERRIGHGGTLDPAVTGVLPIAVGRATRLLPYLPS-  63

Query: 133 GKEYVAVLRLHGMRPELDEAT------------VRRAIET----LTGPLYQRPPLISAVK 176
           GK YV  +R  G++   D+ T             R AIE       G + Q+PP +SAV+
Sbjct:  64 GKTYVGTIRF-GLQTSTDDLTGDRLAEADTSHLSREAIEAALPQFLGHIQQQPPQVSAVQ 122

Query: 177 RQ 178
            Q
Sbjct: 123 VQ 124

gb|AAH89592.1| RIKEN cDNA 2610009I02 [Mus musculus]
(338 aa)

Score: 68 bits (166), Expect: 3.43277e-10
Length: 235, Idn/Pos/Gap = 65/97/52 (27%/41%/22%)

Query:  72 SGVINLDKPANPSSHEVV----------------AWIKRILRVEKTGHSGTLDPQVTGCL 115
           SGV  + KP  P+S E+                  W KR  +  K GH GTLD    G L
Sbjct:  57 SGVFAVHKPKGPTSAELPNRLKEKLLAEAGMPSPEWNKRQKQTLKVGHGGTLDSAAQGVL 116

Query: 116 IVCIERATRLVKSQQSAGKEYVAVLRLHGMRPELD-----------EATVRRAIETL--- 161
           +V I R T+++ S  S  K Y+ +  L      LD           +   R  IE +   
Sbjct: 117 VVGIGRGTKMLTSMLSGSKRYITIGELGKATDTLDSTGKVTEEKPYDKITREDIEGILQK 176

Query: 162 -TGPLYQRPPLISAVKRQ-LRIRTIYES-KLLEYDPKRRLVLFWVS-------------- 204
            TG + Q PPL SA+K+   R+ T+ +  K++E  P R + +  +S              
Sbjct: 177 FTGNIMQVPPLYSALKKDGQRLSTLMKKGKVVEARPARPVTVHSISLLKFQPPFFTLDVE 236

Query: 205 CEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFD 259
           C  G YIR+L   +G  L     + EL R + G  +     +  H + + +W  D
Sbjct: 237 CGGGFYIRSLVSDIGKELSSCASVLELTRTKQGPFT-----LAQHALPEDRWTID 286

dbj|BAA37097.1| tRNA pseudoridine 55 synthase [Synechococcus sp.]
(153 aa)

Score: 68 bits (166), Expect: 3.66973e-10
Length: 122, Idn/Pos/Gap = 51/69/18 (41%/56%/14%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           G +NLDKPA  +SH+ VA ++R+LR  + GH GTLDP VTG L + + RATRL+    S 
Sbjct:   5 GFVNLDKPAGWTSHDCVAKLRRLLRERRIGHGGTLDPAVTGVLPIAVGRATRLLPYLPS-  63

Query: 133 GKEYVAVLRLHGMRPELDEAT------------VRRAIET----LTGPLYQRPPLISAVK 176
           GK YV  +R  G++   D+ T             R AIE       G + Q+PP +SAV+
Sbjct:  64 GKTYVGTIRF-GLQTSTDDLTGDRLAEADTSHLSREAIEAALPQFLGHIQQQPPQVSAVQ 122

Query: 177 RQ 178
            Q
Sbjct: 123 VQ 124

sp|Q5NQ30|TRUB_ZYMMO tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
gb|AAV89175.1| tRNA pseudouridine synthase B [Zymomonas mobilis subsp. mobilis ZM4]
ref|YP_162286.1| tRNA pseudouridine synthase B [Zymomonas mobilis subsp. mobilis ZM4]
(303 aa)

Score: 68 bits (166), Expect: 3.89045e-10
Length: 201, Idn/Pos/Gap = 60/90/38 (29%/44%/18%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVE-----KTGHSGTLDPQVTGCLIVCIERATRLVK 127
           G I LDK     S + V+ +KR +R+      K GH GTLDP  +G L V +  AT+L  
Sbjct:  13 GWIILDKQEGLGSTQAVSAVKRAIRIAGLPKVKVGHGGTLDPLASGVLPVALGEATKLAG  72

Query: 128 SQQSAGKEYVAVL----------RLHGMRPELDEATVRRAIETL----TGPLYQRPPLIS 173
              ++ K Y   L          R   +  + D+   R  +E++     G ++Q PP+ S
Sbjct:  73 YALNSDKVYAFTLAFGAETDSLDREGSITAQSDKRPTREEVESVLSCFRGEIHQIPPVYS 132

Query: 174 AVKRQ-----LRIR------------TIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCV 216
           A+K        R+R            TI+E  L ++ P +    F      GTYIR+L  
Sbjct: 133 ALKINGKRACDRVRAGETVTVKGRDITIHELTLDDFSPDQ--ATFIAKVSKGTYIRSLAR 190

Query: 217 HLGLLLGVGGHMQELRRVRSG 237
            +   L   GH+  LRR++SG
Sbjct: 191 DIAHKLNCYGHVSYLRRLKSG 211

ref|YP_191981.1| tRNA pseudouridine synthase B [Gluconobacter oxydans 621H]
gb|AAW61325.1| tRNA pseudouridine synthase B [Gluconobacter oxydans 621H]
sp|Q5FQM1|TRUB_GLUOX tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(333 aa)

Score: 68 bits (165), Expect: 4.95548e-10
Length: 201, Idn/Pos/Gap = 59/85/42 (29%/42%/20%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           G + LDKP  P+S ++V  ++     +K GH GTLDP  +G L +   +ATR +     A
Sbjct:  11 GWLILDKPLGPTSTDMVNKLRWAFDAKKAGHGGTLDPLASGVLPIAFGKATRTIPYIMDA  70

Query: 133 GKEYV----------------AVLRLHGMRPELDEATVRRAIETLTGPLYQRPPLISAVK 176
            K Y                  VL     RP  D+  +R  +  LTG + Q PP+ SA++
Sbjct:  71 TKRYRFTLTFGESRTTDDLEGEVLATSPNRPTDDQ--IRAVLPALTGNVMQVPPVFSALR 128

Query: 177 --------------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCV 216
                               R  RI +I    L+E  P     +F V    G Y+R+L  
Sbjct: 129 VGGERAYDMARAGRPPELPPRPARIDSI---TLVE-RPDANTAVFDVQSGKGVYMRSLAR 184

Query: 217 HLGLLLGVGGHMQELRRVRSG 237
            + L  G  GH+  LRR + G
Sbjct: 185 DIALACGTVGHISVLRRTKCG 205

gb|AAL94831.1| tRNA pseudouridine synthase B [Fusobacterium nucleatum subsp. nucleatum ATCC 25586]
ref|NP_603532.1| tRNA pseudouridine synthase B [Fusobacterium nucleatum subsp. nucleatum ATCC 25586]
sp|Q8R5X8|TRUB_FUSNN tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(287 aa)

Score: 67 bits (162), Expect: 9.11196e-10
Length: 199, Idn/Pos/Gap = 55/95/33 (27%/47%/16%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           G+I ++KP   +S +V+  +K+ L+ +K GH+GTLDP   G ++VC+ +AT+L    ++ 
Sbjct:   3 GIIVINKPKGITSFDVIRKLKKFLKTKKIGHTGTLDPLAIGVMLVCVGKATKLASDLEAK  62

Query: 133 GKEYVA---------VLRLHGMR-----PELDEATVRRAIETLTGPLYQRPPLISAVK-- 176
            K Y+A            + G +      E+ +  + ++++   G + Q PP+ SA+K  
Sbjct:  63 DKVYIADFDIGYATDTYDIEGKKIAENIIEVSKENLEQSLKKFIGNIKQVPPMYSAIKID 122

Query: 177 ---------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLL 221
                          R  R  TI    LL++   +  +   VS   G YIR+L   +G  
Sbjct: 123 GNKLYHLARKGIEVERPERDITIEYINLLDFKDNKAKIETKVS--KGCYIRSLIYDIGQD 180

Query: 222 LGVGGHMQELRRVRSGVHS 240
           LG    M  L+R + G +S
Sbjct: 181 LGTYATMTALQRKQVGEYS 199

ref|XP_546809.1| PREDICTED: similar to Cadherin-13 precursor (Truncated-cadherin) (T-cadherin) (T-cad) (Heart-cadherin) (H-cadherin) (P105) [Canis familiaris]
(2279 aa)

Score: 65 bits (159), Expect: 2.35889e-09
Length: 40, Idn/Pos/Gap = 29/35/0 (72%/87%/0%)

Query:   72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQV  111
            +G  +LDKP+NPS HE+VAWI+RILRVEKTGHSG LD +V
Sbjct: 1916 TGSTHLDKPSNPSPHEMVAWIRRILRVEKTGHSGILDSKV 1955

gb|AAH54088.1| 2610009I02Rik protein [Mus musculus]
(289 aa)

Score: 65 bits (158), Expect: 3.34889e-09
Length: 200, Idn/Pos/Gap = 57/86/36 (28%/43%/18%)

Query:  91 WIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAGKEYVAVLRLHGMRPELD 150
           W KR  +  K GH GTLD    G L+V I R T+++ S  S  K Y+ +  L      LD
Sbjct:  43 WNKRQKQTLKVGHGGTLDSAAQGVLVVGIGRGTKMLTSMLSGSKRYITIGELGKATDTLD 102

Query: 151 -----------EATVRRAIETL----TGPLYQRPPLISAVKRQ-LRIRTIYES-KLLEYD 193
                      +   R  IE +    TG + Q PPL SA+K+   R+ T+ +  K++E  
Sbjct: 103 STGKVTEEKPYDKITREDIEGILQKFTGNIMQVPPLYSALKKDGQRLSTLMKKGKVVEAR 162

Query: 194 PKRRLVLFWVS--------------CEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVH 239
           P R + +  +S              C  G YIR+L   +G  L     + EL R + G  
Sbjct: 163 PARPVTVHSISLLKFQPPFFTLDVECGGGFYIRSLVSDIGKELSSCASVLELTRTKQGPF 222

Query: 240 SEYDGMVTMHDVLDAQWLFD 259
           +     +  H + + +W  D
Sbjct: 223 T-----LAQHALPEDRWTID 237

ref|XP_544030.1| PREDICTED: similar to TruB pseudouridine (psi) synthase homolog 1 [Canis familiaris]
(488 aa)

Score: 64 bits (156), Expect: 4.56011e-09
Length: 212, Idn/Pos/Gap = 57/88/47 (26%/41%/22%)

Query:  55 PDAGYSPLKRPIQEYIRSGVINLDKPANPSSHEVV----------------AWIKRILRV  98
           PDA  S      +    SGV  + KP  P+S E++                 W KR  + 
Sbjct: 144 PDARVSKAALATKLLSLSGVFAVHKPKGPTSAELLNRLKEKLLAEAGMPSPEWTKRKKQT 203

Query:  99 EKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAGKEYVAVLRLHGMRPELD-------- 150
            K GH GTLD    G L+V I R T+++    S  K Y+A+  L      LD        
Sbjct: 204 LKIGHGGTLDSAARGVLVVGIGRGTKMLTGMLSGSKRYIAIGELGKATDTLDSTGKVTEE 263

Query: 151 -------EATVRRAIETLTGPLYQRPPLISAVKRQ-LRIRTIYE-SKLLEYDPKRRLVLF 201
                  +  +   ++  TG + Q PPL SA+K+   R+ T+ +  +++E  P R + ++
Sbjct: 264 KPYDKITQEDIEGILQKFTGNIMQVPPLYSALKKDGQRLSTLMKRGEVVEAKPARPVTVY 323

Query: 202 WVS--------------CEAGTYIRTLCVHLG 219
            +S              C  G YIR+L   +G
Sbjct: 324 SLSLQKFQPPFFTLDVECGGGFYIRSLVSDIG 355

gb|AAU92658.1| tRNA pseudouridine synthase B, interruption-N [Methylococcus capsulatus str. Bath]
ref|YP_113775.1| tRNA pseudouridine synthase B, interruption-N [Methylococcus capsulatus str. Bath]
sp|Q609C2|TRUB_METCA tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(224 aa)

Score: 64 bits (156), Expect: 4.79421e-09
Length: 130, Idn/Pos/Gap = 41/65/17 (31%/50%/13%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           SGV+ LDK +  +S+  +   +++L + K GH+G+LDP  +G L +C   AT+L      
Sbjct:  10 SGVLLLDKGSGMTSNSALQRARKLLDMRKAGHTGSLDPLASGILPLCFNEATKLSSYLLD  69

Query: 132 AGKEYVAV---------------LRLHGMRPELDEATVRRAIETLTGPLYQRPPLISAVK 176
           + K Y  +               +RL    P LDE  +   +   TGP+ Q PP+ SA+K
Sbjct:  70 SDKRYRVLARLGVTTDTGDADGEVRLRTPVPALDEPALLTVLAGFTGPILQVPPMFSALK 129

Query: 177 RQLRIRTIYE 186
              R + +YE
Sbjct: 130 H--RGKRLYE 137

ref|XP_521611.1| PREDICTED: similar to TruB pseudouridine (psi) synthase homolog 1 [Pan troglodytes]
(340 aa)

Score: 64 bits (156), Expect: 4.83438e-09
Length: 213, Idn/Pos/Gap = 57/88/56 (26%/41%/26%)

Query:  72 SGVINLDKPANPSSHEVV----------------AWIKRILRVEKTGHSGTLDPQVTGCL 115
           SGV  + KP  P+S E++                 W KR  +  K GH GTLD    G L
Sbjct:  69 SGVFAVHKPKGPTSAELLNRLKEKLLAEAGMPSPEWTKRKKQTLKIGHGGTLDSAARGVL 128

Query: 116 IVCIERATRLVKSQQSAGKEYVAVLRLHGMRPELD---------------EATVRRAIET 160
           +V I   T+++ S  S  K Y A+  L      LD               +  +   ++ 
Sbjct: 129 VVGIGSGTKMLTSMLSGSKRYTAIGELGKATDTLDSTGKVTEEKPYDKITQEDIEGILQK 188

Query: 161 LTGPLYQRPPLISAVKRQ-LRIRTIYE-SKLLEYDPKRRLVLFWVS-------------- 204
            TG + Q PPL SA+K+   R+ T+ +  +++E  P R + ++ +S              
Sbjct: 189 FTGNIMQVPPLYSALKKDGQRLSTLMKRGEVVEAKPARPVTVYSISLQKFQPPFFTLDVE 248

Query: 205 CEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSG 237
           C  G YIR+L   +G         +EL R + G
Sbjct: 249 CGGGFYIRSLVSDIG---------KELTRTKQG 272

gb|AAU07651.1| tRNA pseudouridine 55 synthase [Borrelia garinii PBi]
ref|YP_073243.1| tRNA pseudouridine 55 synthase [Borrelia garinii PBi]
sp|Q65ZX0|TRUB_BORGA tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(282 aa)

Score: 64 bits (155), Expect: 6.80628e-09
Length: 201, Idn/Pos/Gap = 50/85/33 (24%/42%/16%)

Query:  70 IRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQ 129
           + +G + ++K    +S E +  IK+       GH+GTLD   +G LI  + + T+L    
Sbjct:   1 MENGFLLINKEQGKTSFETLFPIKKYFNTNHVGHAGTLDKFASGILIALVGKYTKLAGYF  60

Query: 130 QSAGKEYVAVLRLHGMRPELDE--ATVRRA------------IETLTGPLYQRPPLISAV 175
            S  KEYVA  R       LD     V +A            ++   G +YQ PP  S++
Sbjct:  61 ISLDKEYVAEFRFGLETDTLDSNGRIVNKADYIPSVEDIDLKLKDFVGEIYQSPPRFSSI 120

Query: 176 K------------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVH 217
                              ++ R+  +Y+ + L YD     +   ++C  GTYIR++   
Sbjct: 121 HIDGIRAYKLALNGKFFEIKKRRV-NVYDIQRLSYDFSSSSLSLKITCSKGTYIRSIARD 179

Query: 218 LGLLLGVGGHMQELRRVRSGV 238
           L   L    ++  L+R + G+
Sbjct: 180 LAYSLNSCAYVSNLKRTKIGM 200

ref|NP_078188.1| tRNA pseudouridine 55 synthase [Ureaplasma parvum serovar 3 str. ATCC 700970]
gb|AAF30763.1| tRNA pseudouridine 55 synthase [Ureaplasma parvum serovar 3 str. ATCC 700970]
sp|Q9PQD7|TRUB_UREPA tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
pir||B82902 tRNA pseudouridine 55 synthase UU354 [imported] - Ureaplasma urealyticum
(227 aa)

Score: 63 bits (154), Expect: 7.71374e-09
Length: 187, Idn/Pos/Gap = 47/88/34 (25%/47%/18%)

Query:  84 SSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAGKEYVAVLRLH 143
           +S++VV  +KR++  +K GH+GTLDP  +G L++ I   T+L+       K Y+A ++  
Sbjct:  18 TSNDVVQKVKRVIGAKKVGHAGTLDPNASGVLVLGINEGTKLLTKLILDNKSYIAEIKFG  77

Query: 144 GMRPELDEA-----TVRRAIETLT-----------GPLYQRPPLISAVK----------R 177
                 D A     +  R + TLT              +Q+PP  SA+K          R
Sbjct:  78 TSTNTYDAAGEIVSSTNRMV-TLTEVTKIVKDFYKNDYWQKPPQFSALKINGQKAYVLAR 136

Query: 178 QL-------RIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLLLGVGGHMQE 230
           Q        R+  I++ ++++++ +++++   +    G Y+R+  V L   +    H+  
Sbjct: 137 QKVDFEIAPRLVKIFKYQIMDFNYEKQILKISLHVSKGFYVRSFAVDLATKINNLAHLLT 196

Query: 231 LRRVRSG 237
           L R +SG
Sbjct: 197 LIRTQSG 203

ref|ZP_00121517.2| COG0130: Pseudouridine synthase [Bifidobacterium longum DJO10A]
(387 aa)

Score: 63 bits (154), Expect: 9.50289e-09
Length: 81, Idn/Pos/Gap = 33/51/1 (40%/62%/1%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           SG++ +DKP   +S + VA ++  L ++K GH+GTLDP  TG L++    ATRL+ +  +
Sbjct:   7 SGLLIIDKPQGVTSFDAVAAVRGALHIKKVGHAGTLDPMATGTLVIAFGHATRLLNAIVA  66

Query: 132 AGKEYVAVLRLHGMRPELDEA 152
             K Y A +RL G+R   D+A
Sbjct:  67 HDKTYEATIRL-GLRTTTDDA  86


Score: 43 bits (102), Expect: 0.00812385
Length: 56, Idn/Pos/Gap = 23/33/3 (41%/58%/5%)

Query: 203 VSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSG---VHSEYDGMVTMHDVLDAQ 255
           +SC +GTYIR L   LG  LGVGG++  LRR R G   +  +  G++    +LD +
Sbjct: 216 ISCSSGTYIRALARDLGKELGVGGYLTRLRRTRVGRFALPDDASGLIAPEAMLDTR 271

sp|Q8CY45|TRUB_BIFLO tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
ref|NP_696770.1| tRNA pseudouridine synthase B [Bifidobacterium longum NCC2705]
gb|AAN25406.1| tRNA pseudouridine synthase B [Bifidobacterium longum NCC2705]
(387 aa)

Score: 63 bits (154), Expect: 9.50289e-09
Length: 81, Idn/Pos/Gap = 33/51/1 (40%/62%/1%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           SG++ +DKP   +S + VA ++  L ++K GH+GTLDP  TG L++    ATRL+ +  +
Sbjct:   7 SGLLIIDKPQGVTSFDAVAAVRGALHIKKVGHAGTLDPMATGTLVIAFGHATRLLNAIVA  66

Query: 132 AGKEYVAVLRLHGMRPELDEA 152
             K Y A +RL G+R   D+A
Sbjct:  67 HDKTYEATIRL-GLRTTTDDA  86


Score: 43 bits (102), Expect: 0.00812385
Length: 56, Idn/Pos/Gap = 23/33/3 (41%/58%/5%)

Query: 203 VSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSG---VHSEYDGMVTMHDVLDAQ 255
           +SC +GTYIR L   LG  LGVGG++  LRR R G   +  +  G++    +LD +
Sbjct: 216 ISCSSGTYIRALARDLGKELGVGGYLTRLRRTRVGRFALPDDASGLIAPEAMLDTR 271

ref|ZP_00271081.1| COG0130: Pseudouridine synthase [Rhodospirillum rubrum]
(308 aa)

Score: 62 bits (151), Expect: 2.11702e-08
Length: 195, Idn/Pos/Gap = 58/83/30 (29%/42%/15%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           G + +DKP   +S +VV  ++R +   K GH GTLDP  +G L +    AT+ V      
Sbjct:  12 GWLAIDKPVGITSTDVVNRLRRTMDAAKVGHGGTLDPLASGVLPIAFGEATKTVSYVMDG  71

Query: 133 GKEYVAVLRLHGMRPE-------LDEATVR---RAIETL----TGPLYQRPPLISAVKRQ 178
            K Y  V+     R         +D + VR   +AI  +    TG + Q PP+ SAVK +
Sbjct:  72 TKVYHMVVGWGEARDTDDREGKVIDTSDVRPDAQAITAMLARFTGEIEQVPPIYSAVKVE 131

Query: 179 LRIRTIYESKLLEYDPKRRLVL----------------FWVSCEAGTYIRTLCVHLGLLL 222
            R            + K R +L                F +    G Y+R+L   L L L
Sbjct: 132 GRRSYDLARADQAVELKSRKILIKDLTLLETSTPDFGHFRIVSGKGAYMRSLARDLALAL 191

Query: 223 GVGGHMQELRRVRSG 237
           G  GH+  LRR+  G
Sbjct: 192 GTVGHVVALRRLACG 206

ref|YP_016163.1| tRNA pseudouridine synthase B [Mycoplasma mobile 163K]
gb|AAT27952.1| tRNA pseudouridine synthase B [Mycoplasma mobile 163K]
sp|Q6KHH8|TRUB_MYCMO tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(287 aa)

Score: 62 bits (150), Expect: 2.71916e-08
Length: 197, Idn/Pos/Gap = 58/78/34 (29%/39%/17%)

Query:  74 VINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAG 133
           ++ L K  N SS   +   K+    +K GH GTLDP  TG LIV  +  T+L+       
Sbjct:   4 ILLLRKTKNISSFNFINNFKKTKGFKKIGHCGTLDPLATGLLIVATDEDTKLIDYLDQKD  63

Query: 134 KEYVAVLRLHGMRPELDEA------------TVRRAIETLT---GPLYQRPPLISAVK-- 176
           K YVA  +L       D              T  + IE L    G   Q PP  SA K  
Sbjct:  64 KTYVARAKLGFETTTYDSEGEIINQSSNVKFTKEKLIEVLNSFIGLTKQMPPKYSAKKLN 123

Query: 177 ----------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGL 220
                            ++ I  I + KLL Y+       F V    GTYIR+L   +G+
Sbjct: 124 GIRAYDLARQNIDFELNEVEI-NITKIKLLSYNEDENYFDFEVVVSRGTYIRSLIYDIGI 182

Query: 221 LLGVGGHMQELRRVRSG 237
            L    +M+ L R + G
Sbjct: 183 KLNSLAYMESLERTKIG 199

emb|CAD74785.1| tRNA pseudouridine synthase B [Rhodopirellula baltica SH 1]
ref|NP_867239.1| tRNA pseudouridine synthase B [Rhodopirellula baltica SH 1]
sp|P59883|TRUB_RHOBA tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(348 aa)

Score: 62 bits (149), Expect: 2.90686e-08
Length: 273, Idn/Pos/Gap = 74/114/73 (27%/41%/26%)

Query:  55 PDAGYSPLKRPIQEYIRSGVINLDKPANPSSHEVVAWIKRILRVE------KTGHSGTLD 108
           P+  +SPL          G +   KP   +S ++V   +R LR E      K GH+GTLD
Sbjct:   3 PNGEHSPL----------GFLPCYKPPGATSRDLVNRAQRRLRGEFGLRKLKVGHTGTLD  52

Query: 109 PQVTGCLIVCIERATRLVKSQQSAGKEYVAVLRLHGMRPELDE----------------A 152
           P   G +++ I  A RL       GK Y+A  RL G+  E  +                A
Sbjct:  53 PLAEGLVLLAIGSAARLTPWVLQHGKRYLADFRL-GVSSESGDLESELVTQTDVKLPTAA 111

Query: 153 TVRRAIETLTGPLYQRPPLISAV--------------------KRQLRIRTIYESKLLEY 192
            + + ++   G + Q PP  SA+                    KR++ I ++   KL+ Y
Sbjct: 112 EIEQVLKDFHGVVEQTPPAHSAIKVDGERAHKRARRGEDFEMPKRRILIDSV---KLISY 168

Query: 193 DPKRRLVLFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVL 252
           +P   ++   V C +GTY+RTL + +    G    M +L  +R+ V     G  T+ D L
Sbjct: 169 EPP--MMRLDVRCGSGTYLRTLGMDVAAACGCAAVMTKL--IRNEV-----GRFTLDDTL 219

Query: 253 DAQWLFDTTKDE--------SYLRRVIKPLESL 277
           D  ++FD    E         YLR  I+ L  +
Sbjct: 220 DCAFMFDDDDREKMSSEPMVKYLRPAIEGLTHM 252

gb|AAB48163.1| Orp [Pseudomonas aeruginosa]
(139 aa)

Score: 61 bits (148), Expect: 4.09255e-08
Length: 120, Idn/Pos/Gap = 40/61/14 (33%/50%/11%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQS 131
           SG++ LDKP   SS++ +  ++ +L  EK GH+G+LDP  TG L +C   AT+  +    
Sbjct:  12 SGILVLDKPRGMSSNQALQKVRWLLNAEKAGHTGSLDPLATGVLPLCFGEATKFSQYLLD  71

Query: 132 AGKEYVAVLRL---------HGMRPELDEATVRR-----AIETLTGPLYQRPPLISAVKR 177
           A K Y  V+R+          G      + TV R     A+    G + Q PP+ SA+K+
Sbjct:  72 ADKGYETVMRMGITTTTGDAEGELLAERDVTVGRDDLEQALPRFRGDIEQVPPMYSALKK 131

emb|CAA79237.1| ORF7 [Bacillus subtilis]
(65 aa)

Score: 61 bits (148), Expect: 4.83578e-08
Length: 56, Idn/Pos/Gap = 26/43/0 (46%/76%/0%)

Query:  72 SGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVK 127
           +GV+ L KP   +SH+ V  I+++L+ +K GH+GTLDP+V+G L +C+ RAT++V+
Sbjct:   3 NGVLLLHKPVGMTSHDCVMKIRKLLKTKKVGHTGTLDPEVSGVLPICVGRATKIVE  58

gb|AAK39672.1| putative pseudouridylate synthase [Guillardia theta]
ref|NP_113099.1| putative pseudouridylate synthase [Guillardia theta]
pir||C90122 putative pseudouridylate synthase [imported] - Guillardia theta nucleomorph
(310 aa)

Score: 61 bits (147), Expect: 5.38982e-08
Length: 249, Idn/Pos/Gap = 53/115/7 (21%/46%/2%)

Query:  74 VINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCI-ERATRLVKSQQSA 132
           +I +DKP   +S E++  +          +   L+   +GC+I  I + + +  +     
Sbjct:   6 LIVIDKPIGLNSIELIKILNSKFPSYAIFNINYLNTNTSGCVIYSIFDYSNKFKEILNEI  65

Query: 133 GKEYVAVLRLHGMRPELDEATVRRAIETLTGPLYQRPPLISAVKRQLRIRTIYESKLLEY 192
            KE++  + L      L    +++ I   +  L +   +I    + LR+       L+E 
Sbjct:  66 LKEFIIFINLKIFCYNL---LIKKII---SFSLLKNNTMIRNSIKFLRVINKIFLSLIEI 119

Query: 193 DPKRRLVLFWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMHDVL 252
               R ++F +S        ++   +  + G   +  E R+V+ G  SE +  +T ++ L
Sbjct: 120 QTIDRFIIFIISSYNNLCYNSIFQVIKTIFGNNLNYLEYRQVKIGSISEDNFSITFYEFL 179

Query: 253 DAQWLFDTTKDESYLRRVIKPLESLLVHHKRIVIKDSCVNAVCYGAKLMLPGVLRYENDI 312
           D   +    K+   +  VI  LES+    K+++IK SC+N + YG+++ +PG+++    +
Sbjct: 180 DILSIHFFYKNTKVVENVIISLESIYRFLKKVIIKKSCINTIYYGSRIYVPGIIKISKSL 239

Query: 313 ECGEEVVIM 321
           + G+++ I+
Sbjct: 240 KSGDKIKIL 248

ref|ZP_00302676.1| COG0130: Pseudouridine synthase [Novosphingobium aromaticivorans DSM 12444]
(304 aa)

Score: 60 bits (146), Expect: 6.69559e-08
Length: 209, Idn/Pos/Gap = 65/85/49 (31%/40%/23%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVE-----KTGHSGTLDPQVTGCLIVCIERATRLVK 127
           G I LDKP    S + VA +KR LR       K GH GTLDP  TG L + +  AT+L  
Sbjct:   4 GWIILDKPLELGSTQGVAAVKRNLRQAGYGKCKVGHGGTLDPLATGVLPIAVGEATKLCG  63

Query: 128 SQQSAGKEYVAV---------LRLHG-------MRPELDEATVRRAIETLTGPLYQRPPL 171
               A K Y            L L G       +RP L  A V   +      + Q PP 
Sbjct:  64 RMLDASKVYAFTVAFGTETDSLDLEGGIVATSDVRPPL--ADVHVTLGAFRDSIDQVPPA 121

Query: 172 ISAV----KRQLRIRTIYESKLLEYDPKRRLVLF------WVSCEA-------------G 208
            SA+    +R   +    E+  L   P RR+ +       W   E              G
Sbjct: 122 YSALMVEGRRAYDLARAGETVEL---PSRRVTIHALTLDSWTGSEGAVETATLTAHVSKG 178

Query: 209 TYIRTLCVHLGLLLGVGGHMQELRRVRSG 237
           TYIR+L   +   LG  GH+  LRR+++G
Sbjct: 179 TYIRSLARDIARALGTVGHVTMLRRLKAG 207

pir||C57253 tRNA-pseudouridine synthase (EC 5.4.99.-) - Acinetobacter calcoaceticus (fragment)
(151 aa)

Score: 60 bits (145), Expect: 8.52853e-08
Length: 133, Idn/Pos/Gap = 40/63/20 (30%/47%/15%)

Query:  63 KRPIQEYIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERA 122
           +RP+     SGV  L+KP   SS+ V+  ++ + R +K GH+G LDP  TG L +C+  A
Sbjct:  10 RRPV-----SGVFLLNKPLGLSSNGVLQKVRWLFRAQKAGHTGALDPLATGLLPICLGEA  64

Query: 123 TRLVKSQQSAGKEYVAVLRLHGMR---------------PELDEATVRRAIETLTGPLYQ 167
           T+       + K Y  V++L  +                P L    +   ++   G + Q
Sbjct:  65 TKFSHYLLDSTKRYQTVVKLGQVTTTGDVEGKVVQSRSVPPLTRDMLELVLDGFRGDIQQ 124

Query: 168 RPPLISAVKRQLR 180
            PP+ SA+KR  R
Sbjct: 125 VPPMYSALKRDGR 137

ref|NP_084115.1| TruB pseudouridine (psi) synthase homolog 1 [Mus musculus]
dbj|BAB31254.1| unnamed protein product [Mus musculus]
(247 aa)

Score: 60 bits (145), Expect: 1.08633e-07
Length: 166, Idn/Pos/Gap = 50/75/33 (30%/45%/19%)

Query:  72 SGVINLDKPANPSSHEVV----------------AWIKRILRVEKTGHSGTLDPQVTGCL 115
           SGV+ + KP  P+S E++                 W KR  +  K GH GTLD    G L
Sbjct:  57 SGVLAVHKPKGPTSAELLNRLKEKLLAEAGMPSPEWNKRQKQTLKVGHGGTLDSAAQGVL 116

Query: 116 IVCIERATRLVKSQQSAGKEYVAVLRLHGMRPELD-----------EATVRRAIETL--- 161
           +V I R T+++ S  S  K Y+ +  L      LD           +   R  IE +   
Sbjct: 117 VVGIGRGTKMLTSMLSGSKRYITIGELGKATDTLDSTGKVTEEKPYDKITREDIEGILQK 176

Query: 162 -TGPLYQRPPLISAVKRQ-LRIRTIYES-KLLEYDPKRRLVLFWVS 204
            TG + Q PPL SA+K+   R+ T+ +  K++E  P R + +  +S
Sbjct: 177 FTGNIMQVPPLYSALKKDGQRLSTLMKKGKVVEARPARPVTVHSIS 222

ref|ZP_00367128.1| tRNA pseudouridine synthase B, putative [Campylobacter coli RM2228]
gb|EAL57032.1| tRNA pseudouridine synthase B, putative [Campylobacter coli RM2228]
(272 aa)

Score: 60 bits (144), Expect: 1.32717e-07
Length: 191, Idn/Pos/Gap = 57/81/35 (29%/42%/18%)

Query:  79 KPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAGKEYVA 138
           KPA  SS+  +  IK+  + +K G+SGTLDP   G LIV   + T+L +  +   K Y A
Sbjct:   9 KPAEMSSNAFLGQIKKRYKNKKAGYSGTLDPFAKGVLIVAFGQYTKLFRFLKKTPKTYQA  68

Query: 139 VLRLHGMRPELDEATVR-----RAIET---------LTGPLYQRPPLISA---------- 174
            L L      LD   ++     +A +          L G +   PP  SA          
Sbjct:  69 TLWLGVKSLSLDNKNIQEIKLIKAFDIKLLEQIKMELLGKISYTPPQFSAKRIEGKRAYE 128

Query: 175 -VKR----QLR--IRTIYESKLLEYD-PKRRLVLFWVSCEAGTYIRTLCVHLGLLLGVGG 226
             KR    +L+  I  I+  K++ Y  P  +L L   S   G YIR+ C      LG+  
Sbjct: 129 FAKRGENIELKSCIMEIFSCKIIHYTHPFLQLEL---SVSEGAYIRSYCELFAKKLGINA 185

Query: 227 HMQELRRVRSG 237
            +  L R R G
Sbjct: 186 TLSSLERTREG 196

gb|AAP76721.1| tRNA pseudouridine synthase B [Helicobacter hepaticus ATCC 51449]
ref|NP_859655.1| tRNA pseudouridine synthase B [Helicobacter hepaticus ATCC 51449]
sp|Q7U330|TRUB_HELHP tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(284 aa)

Score: 58 bits (141), Expect: 2.60881e-07
Length: 193, Idn/Pos/Gap = 54/78/33 (27%/40%/17%)

Query:  79 KPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAGKEYVA 138
           KP   SS+  ++ +K+   + K G+ GTLDP   G L+V     TRL    Q   K Y A
Sbjct:  11 KPPFLSSNACLSRLKKHFGMSKAGYLGTLDPFAKGVLVVGFGSYTRLFPHLQKVPKAYRA  70

Query: 139 VLRLHGMRPELD--------------EATVRRAIETLTGPLYQRPPLISA---------- 174
            L L      LD              ++ + + + +L G     PP  SA          
Sbjct:  71 TLWLGAKSASLDIEHIESIEIIPEYNQSDIEKILFSLKGTFDYTPPAFSAKHINGQRAYK 130

Query: 175 VKRQLRIRT-------IYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLLLGVGGH 227
           + R+ ++ T       IY   LL Y      V F VS   G Y+R++   +   LGV G 
Sbjct: 131 LAREGKVFTLQQIQMSIYNITLLSY--HHPFVHFEVSVSEGAYVRSIGEIIAKKLGVNGV 188

Query: 228 MQELRRVRSGVHS 240
           +  L R+  G  S
Sbjct: 189 LSSLERISEGQMS 201

ref|YP_005738.1| tRNA pseudouridine 55 synthase [Thermus thermophilus HB27]
ref|YP_143483.1| tRNA pseudouridine 55 synthase [Thermus thermophilus HB8]
sp|Q72GS9|TRUB_THET2 tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
sp|Q5SLS6|TRUB_THET8 tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
gb|AAS82111.1| tRNA pseudouridine 55 synthase [Thermus thermophilus HB27]
dbj|BAD70040.1| tRNA pseudouridine 55 synthase [Thermus thermophilus HB8]
(312 aa)

Score: 58 bits (141), Expect: 2.81226e-07
Length: 114, Idn/Pos/Gap = 41/56/14 (35%/49%/12%)

Query:  77 LDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAGKEY 136
           +DKP + +SH+VV   +R L   + GH+GTLDP  TG L++    +T+LV       KEY
Sbjct:   6 VDKPLHLTSHDVVEEARRRLSTRRVGHTGTLDPLATGLLLLVTNESTKLVPFLSGEDKEY  65

Query: 137 VAVLRLHGMRPELD-------EATVRRAIETLTGPL-------YQRPPLISAVK 176
           +A +      P LD       EA  R   + L   L        Q PPL SA+K
Sbjct:  66 IAWVSFGATTPTLDAEGPISEEAPARFDRKDLEAALPRFLEVREQVPPLYSAIK 119

ref|YP_115618.1| tRNA pseudouridine synthase B [Mycoplasma hyopneumoniae 232]
gb|AAV27711.1| tRNA pseudouridine synthase B [Mycoplasma hyopneumoniae 232]
sp|Q601U7|TRUB_MYCHY tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(327 aa)

Score: 58 bits (140), Expect: 3.92646e-07
Length: 216, Idn/Pos/Gap = 54/99/38 (25%/45%/17%)

Query:  77 LDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAGKEY 136
           L KP   SS + +    +   ++K GH+GTLDP  +G L+V  E  T+L++      K Y
Sbjct:  52 LYKPKKISSAKFLRQWSKTNLIKKAGHAGTLDPLASGLLLVATEDDTKLLQYLDQKTKTY 111

Query: 137 VAVL-------------RLHGMRP--ELDEATVRRAIETLTGPLYQRPPLISAVK----- 176
           +A +             +++G+    ++ +  + +A+  L+    Q PP+ S+ K     
Sbjct: 112 LAKIQFGFWSTTYDAEGQIYGVEQPIKVTKDNLEQALNRLSESQKQVPPVFSSKKVSGKS 171

Query: 177 --------RQLRIR----TIYESKLLEYDPK-RRLVLFWVSCEAGTYIRTLCVHLGLLLG 223
                   +Q+ ++     I ++ L+ +D K +  V+ W     G YIR+L   LG +L 
Sbjct: 172 AYHYARQGKQIELKPISIKISKTILINFDEKLQNCVIMW-QVSRGCYIRSLADDLGKMLK 230

Query: 224 VGGHMQELRRVRSGVHSEYDGMVTMHDVLDAQWLFD 259
              ++ +L R + G    +D    ++  L  Q LFD
Sbjct: 231 TRAYLSDLERTKIG---NFDKKF-LNQSLKPQDLFD 262

ref|NP_220877.1| TRNA PSEUDOURIDINE 55 SYNTHASE (truB) [Rickettsia prowazekii str. Madrid E]
emb|CAA14953.1| TRNA PSEUDOURIDINE 55 SYNTHASE (truB) [Rickettsia prowazekii]
sp|Q9ZD46|TRUB_RICPR tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(172 aa)

Score: 55 bits (133), Expect: 2.48214e-06
Length: 165, Idn/Pos/Gap = 42/70/31 (25%/42%/18%)

Query:  75 INLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAGK 134
           +N  KP   SS ++V  +K+I+   K GH+GTLD +  G L + +  AT+L++    A K
Sbjct:   6 LNFYKPRGISSAKLVNIVKKIIGKTKIGHAGTLDVEAEGILPLAVGEATKLIQLLIDARK  65

Query: 135 EYVAVLRLHGMRPELD--------------EATVRRAIETLTGPLYQRPPLISAVK---- 176
            Y+  ++        D              +  V        G + Q PP+ SA+K    
Sbjct:  66 TYIFSVKFGTQTDSGDYTGKVIASKDYIPSQEEVYTVCSKFIGNIRQVPPIFSAIKVNGV 125

Query: 177 -----------RQLRIR--TIYESKLLEYDPKRRLVLFWVSCEAG 208
                       +L+ R  TIY+ K L +D +  +  ++  C  G
Sbjct: 126 RAYKLAREGKIVELKPRNITIYDLKCLNFDKENAIATYYTECSKG 170

ref|YP_179233.1| tRNA pseudouridine synthase B [Campylobacter jejuni RM1221]
gb|AAW35567.1| tRNA pseudouridine synthase B [Campylobacter jejuni RM1221]
sp|Q5HU02|TRUB_CAMJR tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(272 aa)

Score: 53 bits (128), Expect: 9.04673e-06
Length: 191, Idn/Pos/Gap = 49/81/35 (25%/42%/18%)

Query:  79 KPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAGKEYVA 138
           KP   SS+  ++ +K+  + +K G+SGTLDP   G LIV   + T+L +  +   K Y A
Sbjct:   9 KPKGLSSNAFLSTLKKKYKNKKAGYSGTLDPFAKGVLIVAFGQYTKLFRFLKKTPKTYKA  68

Query: 139 VLRLHGMRPELDE--------------ATVRRAIETLTGPLYQRPPLISAVKRQLRIRT- 183
            L L      LD+              A +++ I+ + G +   PP  SA KR    R  
Sbjct:  69 TLWLGVYSLSLDDQNIKEIQNIKEFDLANLKQIIDQMQGIISYTPPQFSA-KRINGTRAY 127

Query: 184 -----------------IYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLLLGVGG 226
                            +++ K+L Y+     +   ++   G YIR+ C      LG+  
Sbjct: 128 ELAKKGIEANLKPCQMEVFDCKILSYN--HPFLNIEITVSEGAYIRSYCELFARKLGINA 185

Query: 227 HMQELRRVRSG 237
            +  L R++ G
Sbjct: 186 TLSSLERIKEG 196

emb|CAH95207.1| tRNA pseudouridine synthase, putative [Plasmodium berghei]
(300 aa)

Score: 53 bits (127), Expect: 1.06897e-05
Length: 269, Idn/Pos/Gap = 64/108/52 (23%/40%/19%)

Query:  22 SDAGENGLSTDSWPLLLKNYDRL----NVRTTHYTPIPDAGYSPLKRPIQEYIRSGVINL  77
           ++   N +S +   + +  Y++     N R  + TP      +  +  I + +  G +N+
Sbjct:  12 TNTSNNNISKNEVDIYITKYEKKILNNNSRIMNLTPSVVQNNTKKEATIDDILYGGFLNI  71

Query:  78 DKPANPSSHEVVAWIKRILR-----------VEKTGHSGTLDPQVTGCLIVCIERATRLV 126
            KP    S +V   IK+IL+             K GH GTLDP   G L++ I+R T  +
Sbjct:  72 YKPVKLYSMKVCEKIKKILKNYFININKNNIKIKVGHGGTLDPFAEGVLMIGIQRGTNEL 131

Query: 127 KSQQSAGKEYVAVLRLHGMRPELD-----------------EATVRRAIETLTGPLYQRP 169
            +     K+Y+AV  L      LD                 + ++   I    G + Q P
Sbjct: 132 SNFLKCYKQYLAVSVLGIETDTLDREGRIIKMKDMKGIKKGDDSITEFINKFIGWIDQIP 191

Query: 170 PLISAVKRQLRIRTIYES----------------KLLEYDPKRRLVLF--WVSCEAGTYI 211
           P+ S+ KR   +R +YE                 K ++Y  +  L  F   + C  GTYI
Sbjct: 192 PIYSS-KRVKGLR-LYEYARKNIPVKIKSNKVHLKNIKYLKELELPFFDLHIHCSGGTYI 249

Query: 212 RTLCVHLGLLLGVGGHMQELRRVRSGVHS 240
           R+L   +   +     + +L R++   HS
Sbjct: 250 RSLIRDIAHSINQYATLIKLIRIKQKEHS 278

emb|CAB73357.1| tRNA pseudouridine synthase B [Campylobacter jejuni subsp. jejuni NCTC 11168]
sp|Q9PNJ2|TRUB_CAMJE tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
ref|NP_282250.1| tRNA pseudouridine synthase B [Campylobacter jejuni subsp. jejuni NCTC 11168]
(272 aa)

Score: 53 bits (127), Expect: 1.11451e-05
Length: 190, Idn/Pos/Gap = 46/81/33 (24%/42%/17%)

Query:  79 KPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAGKEYVA 138
           KP   SS+  ++ +K+  + +K G+SGTLDP   G LIV   + T+L +  +   K Y A
Sbjct:   9 KPRGLSSNAFLSTLKKKYKNKKAGYSGTLDPFAKGVLIVAFGQYTKLFRFLKKTPKTYKA  68

Query: 139 VLRLHGMRPELDEATVR--------------RAIETLTGPLYQRPPLISA---------- 174
            L L      LD+  ++              + I+ + G +   PP  SA          
Sbjct:  69 TLWLGVYSLSLDDQNIKEIKNIKEFDLPNLQQIIDQMQGIISYTPPQFSAKRINGTRAYE 128

Query: 175 -VKRQLRIR------TIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLLLGVGGH 227
             K+ + +        +++ K+L Y+     +   ++   G YIR+ C      LG+   
Sbjct: 129 LAKKGIEVNLKPCQMEVFDCKILSYN--HPFLNIEITVSEGAYIRSYCELFARKLGINAT 186

Query: 228 MQELRRVRSG 237
           +  L R++ G
Sbjct: 187 LSSLERIKEG 196

ref|NP_212937.1| tRNA pseudouridine 55 synthase (truB) [Borrelia burgdorferi B31]
gb|AAC67151.1| tRNA pseudouridine 55 synthase (truB) [Borrelia burgdorferi B31]
sp|O51743|TRUB_BORBU tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(282 aa)

Score: 53 bits (127), Expect: 1.2422e-05
Length: 200, Idn/Pos/Gap = 51/84/31 (25%/42%/15%)

Query:  70 IRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQ 129
           + +G + ++K    +S E +  IK+     + GH+GTLD   +G L+  + + T+L    
Sbjct:   1 MENGFLLINKEQGKTSFETLFPIKKYFNTNRVGHAGTLDKFASGILVCLVGKYTKLSGYF  60

Query: 130 QSAGKEYVAVLRLHGMRPELDE--------------ATVRRAIETLTGPLYQRPPLISAV 175
            S  KEYVA  R       LD                 +   ++   G +YQ PP  S+V
Sbjct:  61 TSLDKEYVAEFRFGLETDTLDPNGRIVSKTDYIPNVEDIDLKLKDFVGEIYQSPPRFSSV 120

Query: 176 -----------------KRQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHL 218
                            + + R  T+Y  + L YD    L+   +SC  GTYIR++   L
Sbjct: 121 HIDGSRAYKLALNGKFFEIKKRKVTVYNIQRLSYDFSSSLLSLKISCSKGTYIRSIARDL 180

Query: 219 GLLLGVGGHMQELRRVRSGV 238
              L    ++  L+R + G+
Sbjct: 181 AYSLNSCAYVSNLKRTKVGM 200

gb|AAC26579.1| tRNA pseudouridine 55 synthase (truB) [Treponema pallidum subsp. pallidum str. Nichols]
ref|NP_219324.1| tRNA pseudouridine 55 synthase (truB) [Treponema pallidum subsp. pallidum str. Nichols]
sp|O83859|TRUB_TREPA tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(366 aa)

Score: 52 bits (124), Expect: 2.56713e-05
Length: 217, Idn/Pos/Gap = 54/86/52 (24%/39%/23%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
            ++   K +  +S   +A ++R+L V+K GH+GTLD    G L++ +   T+L       
Sbjct:   9 AIVPFAKVSGLTSFAALAQVRRLLGVKKVGHTGTLDRFADGLLLLLVGGFTKLAPVMTRL  68

Query: 133 GKEYVAVLRLHGMRPELDE-------------ATVRRAIETLTGPLYQRPPLISAVK--- 176
            K Y A ++       LD              A VR A+   TG + Q PP  SA+K   
Sbjct:  69 EKSYEARIQFGVQTDTLDPEGAVVRCSLFPTFARVRAALPHFTGSIDQVPPEYSALKFGG 128

Query: 177 -------RQ-----LRIRTIY---------ESKLLEYDPKR---------------RLVL 200
                  R+     ++ R ++         E+ L E+   +               R V 
Sbjct: 129 VRASDRVRRGEAVCMKARRVFVFDLQVLGCEADLGEFKKTQAGRGAAIADLDLTRVRAVT 188

Query: 201 FWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSG 237
            +V C AG Y+R L   +    G   ++  LRR R G
Sbjct: 189 LYVRCSAGFYVRALARDIAAACGSCAYVSHLRRTRIG 225

emb|CAI03380.1| hypothetical protein PB301155.00.0 [Plasmodium berghei]
(52 aa)

Score: 52 bits (124), Expect: 2.79051e-05
Length: 48, Idn/Pos/Gap = 21/34/1 (43%/70%/2%)

Query: 16 LSFQIPSDAGENGLSTDSWPLLLKNYDRLNVRTTHYTPIPDAGYSPLK 63
          + ++I  +  E  +   +WPLLLKNYD+LN+R++H+TP+P  G SP +
Sbjct:  4 VEYKIEPEKKEATIDASNWPLLLKNYDKLNIRSSHFTPLP-MGNSPFQ 50

ref|NP_700649.1| tRNA pseudouridine synthase, putative [Plasmodium falciparum 3D7]
gb|AAN35373.1| tRNA pseudouridine synthase, putative [Plasmodium falciparum 3D7]
(560 aa)

Score: 51 bits (121), Expect: 5.26115e-05
Length: 223, Idn/Pos/Gap = 55/91/51 (24%/40%/22%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVE-----------KTGHSGTLDPQVTGCLIVCIER 121
           G +N+ KP    S  V   IK+IL+             K GH GTLDP   G LI+ I++
Sbjct: 327 GFLNIYKPVKLYSMRVCEKIKKILKDYFYKLNKKKVNIKVGHGGTLDPFAEGVLIIGIQQ 386

Query: 122 ATRLVKSQQSAGKEYVA-----------------VLRLHGMRPELDEATVRRAIETLTGP 164
           AT+ +       K+Y+A                 +   H +  +L +  +   ++   G 
Sbjct: 387 ATKKLSDFLKCYKKYLALSIFGYETDTLDREGKIIKEEHVIHKKLKKQDILTNLQKFIGH 446

Query: 165 LYQRPPLISAVKRQLRIRTIYES----------------KLLEYDPKRRLVL--FWVSCE 206
           + Q PP+ SA KR   +R +YE                 K ++Y  +  L     ++ C 
Sbjct: 447 IKQYPPIYSA-KRFKGLR-LYEYARKNISVQIKPCNVHIKDIQYYKEIDLPFLDLYIHCS 504

Query: 207 AGTYIRTLCVHLGLLLGVGGHMQELRRVRSGVHSEYDGMVTMH 249
            GTYIR+L       +   G + +L R      +E++   ++H
Sbjct: 505 GGTYIRSLIRDFANSMNTSGTLIKLVRTE---QNEFNYKNSLH 544

ref|ZP_00370198.1| tRNA pseudouridine synthase B, putative [Campylobacter upsaliensis RM3195]
gb|EAL53721.1| tRNA pseudouridine synthase B, putative [Campylobacter upsaliensis RM3195]
(272 aa)

Score: 50 bits (119), Expect: 0.000105158
Length: 190, Idn/Pos/Gap = 53/81/33 (27%/42%/17%)

Query:  79 KPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAGKEYVA 138
           KPA  SS+  ++ IK+  +V+K G+SGTLDP   G LIV   + T+L +    + K Y A
Sbjct:   9 KPAQISSNAFLSQIKKKYKVKKAGYSGTLDPFAKGVLIVAFNQYTKLFRFLDKSPKSYHA  68

Query: 139 VLRLHGMRPELDEATVR--------------RAIETLTGPLYQRPPLISAVKRQLRIRTI 184
            L L      LD   ++              +A E L G +   PP  SA  +++  +  
Sbjct:  69 TLWLGVKSLSLDTQNIKEVRLLKPFDYKQIQKACEGLLGEISFFPPQFSA--KRIEGKRA 126

Query: 185 YE-SKLLEYDPKRRLVLFWVSCE----------------AGTYIRTLCVHLGLLLGVGGH 227
           YE +K  E  P ++  +   S E                 G Y+R+ C  L   L +   
Sbjct: 127 YEFAKKGEIIPLKKCKMQVFSYEILHYTHPFLSVELKLSEGAYVRSWCELLAQKLEINAT 186

Query: 228 MQELRRVRSG 237
           +  L R+  G
Sbjct: 187 LSSLERLSEG 196

ref|NP_971712.1| tRNA pseudouridine synthase B [Treponema denticola ATCC 35405]
sp|Q73NP8|TRUB_TREDE tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
gb|AAS11593.1| tRNA pseudouridine synthase B [Treponema denticola ATCC 35405]
(357 aa)

Score: 50 bits (119), Expect: 0.000110557
Length: 212, Idn/Pos/Gap = 54/81/48 (25%/38%/22%)

Query:  74 VINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAG 133
           +I   K A  +S   ++ +K+ L  +K GH+GTLD    G L++   + TRL     +  
Sbjct:   8 IIPFAKQAGLTSFASMSAVKKALSTKKVGHTGTLDLFADGLLVLLTGQLTRLADIISAEK  67

Query: 134 KEYVAVLRLHGMRPELDE-------------ATVRRAIETLTGPLYQRPPLISAVK---- 176
           K Y A +        LD                +  +I +  G + QRPP  SA+K    
Sbjct:  68 KTYEAWVEFGTETDTLDPEGEPVLTAPLPSYKNLTESIPSFLGKILQRPPEFSAIKINGK 127

Query: 177 -RQLRIRT------------IYESKL--------LEYDPKR----------RLVLFWVSC 205
               RIR+            I++ +L        LE+  K           R     V C
Sbjct: 128 RASDRIRSGEKIKIAEREIEIFKIELKGIITDSGLEFTEKDFTNINAELKIRYAHIVVEC 187

Query: 206 EAGTYIRTLCVHLGLLLGVGGHMQELRRVRSG 237
             GTYIR+L   L        +++ LRR   G
Sbjct: 188 SKGTYIRSLVRDLARKASSCAYVRALRRTAVG 219

ref|ZP_00290205.1| COG0130: Pseudouridine synthase [Magnetococcus sp. MC-1]
(319 aa)

Score: 49 bits (116), Expect: 0.00023821
Length: 192, Idn/Pos/Gap = 50/74/33 (26%/38%/17%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSA 132
           G + + K    SS +VV  + R  +  K GH GTLDP   G L + +  AT+      + 
Sbjct:  13 GWLAIHKEPGLSSSQVVERVIRTTKANKAGHGGTLDPFSEGVLPIALGEATKTSGMVLNG  72

Query: 133 GKEYVAVLRL----------------HGMRPELDEATVRRAIETLTGPLYQRPPLISAVK 176
            K Y   L+                  G  P   EA +R  +    G + Q PP+ SA++
Sbjct:  73 DKSYRCWLKFGQETDSGDLTGVLLEEQGRVPS--EAELRAVLPQFMGEIEQVPPVFSALR 130

Query: 177 ---------------RQLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLL 221
                           QL  R +   +L     +    +  V+C  GTYIR+L V +   
Sbjct: 131 VDGERAYKRARRGEEVQLASRRVRIDRLELVGFEADTAVLDVACGKGTYIRSLGVDIARA 190

Query: 222 LGVGGHMQELRR 233
           L    H+  L R
Sbjct: 191 LHSRAHLVRLLR 202

ref|ZP_00377081.1| tRNA pseudouridine synthase B [Erythrobacter litoralis HTCC2594]
gb|EAL73995.1| tRNA pseudouridine synthase B [Erythrobacter litoralis HTCC2594]
(362 aa)

Score: 48 bits (115), Expect: 0.000291023
Length: 122, Idn/Pos/Gap = 39/51/19 (31%/41%/15%)

Query:  73 GVINLDKPANPSSHEVVAWIKRILR-----VEKTGHSGTLDPQVTGCLIVCIERATRLVK 127
           G I LDKP    S + V  +KR LR       K GH GTLDP+  G L + +  AT+L  
Sbjct:  10 GWIILDKPRGLGSTQAVGAVKRNLREGGYAKTKVGHGGTLDPEAEGVLPIALGEATKLAG  69

Query: 128 SQQSAGKEYVAVLRLHGMRPELDE--------------ATVRRAIETLTGPLYQRPPLIS 173
               A K Y   ++       LD               A +   +E  TG + Q PP  S
Sbjct:  70 RMLDASKIYEFTVQFGEETDTLDAEGEITARSDRRPPMAAIAAVLEHFTGEIEQVPPKYS 129

Query: 174 AV 175
           A+
Sbjct: 130 AL 131

emb|CAH81651.1| tRNA pseudouridine synthase, putative [Plasmodium chabaudi]
(186 aa)

Score: 48 bits (113), Expect: 0.000521895
Length: 133, Idn/Pos/Gap = 36/65/15 (27%/48%/11%)

Query:  22 SDAGENGLSTDSWPLLLKNYDR--LNVRTTHYTPIPDAGYSPLKR--PIQEYIRSGVINL  77
           ++  ++ +S +   + +K Y+   LN ++     IP A  +  K+   I + +  G +N+
Sbjct:   3 TNTSDHVISKNEVDMYIKKYESVFLNSKSRIMNLIPSAVQNNTKKEATIDDILYGGFLNI  62

Query:  78 DKPANPSSHEVVAWIKRILR-----------VEKTGHSGTLDPQVTGCLIVCIERATRLV 126
            KP    S +V   IK++L+             K GH GTLDP   G L++ I+R T+ +
Sbjct:  63 YKPVKLYSMKVCEKIKKVLKNYFININKNNIKIKVGHGGTLDPFAEGVLMIGIQRGTKEL 122

Query: 127 KSQQSAGKEYVAV 139
            +     K+Y+AV
Sbjct: 123 SNFLKCYKQYLAV 135

ref|ZP_00299197.1| COG0130: Pseudouridine synthase [Geobacter metallireducens GS-15]
(235 aa)

Score: 48 bits (113), Expect: 0.000539607
Length: 104, Idn/Pos/Gap = 37/47/15 (35%/45%/14%)

Query: 149 LDEATVRRAIETLTGPLYQRPPLISAVKRQ--LRIRTIYESKLLEYDPKR---------R 197
           L    VR       G   Q PP+ SAVK+      R   +   +E +P+          R
Sbjct:  25 LSVEAVREVFGAYIGKCKQIPPMYSAVKQGGVPLYRLARKGHEVEREPRDIEIHSLIIDR  84

Query: 198 LVL----FWVSCEAGTYIRTLCVHLGLLLGVGGHMQELRRVRSG 237
           + L    F VSC  GTY+RTL   +G  LG G H+  LRR RSG
Sbjct:  85 MELPRIEFTVSCSRGTYVRTLAHDMGERLGCGAHLSALRRTRSG 128

ref|NP_907086.1| TRNA PSEUDOURIDINE SYNTHASE B [Wolinella succinogenes DSM 1740]
emb|CAE09986.1| TRNA PSEUDOURIDINE SYNTHASE B [Wolinella succinogenes]
sp|Q7M9J1|TRUB_WOLSU tRNA pseudouridine synthase B (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase)
(291 aa)

Score: 47 bits (112), Expect: 0.000653765
Length: 189, Idn/Pos/Gap = 53/70/31 (28%/37%/16%)

Query:  79 KPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAGKEYVA 138
           KP   SS+  +  +KR   V+K G+SGTLDP   G L+V     TRL        K Y A
Sbjct:  27 KPMFMSSNHYLQRLKRRFGVKKAGYSGTLDPFAKGVLVVAFGHYTRLFDHLNQEPKVYRA  86

Query: 139 VLRLHGMRPELD--------------EATVRRAIETLTGPLYQRPPLISAVKR------- 177
            L L      LD              +  V   +  L G +   PP   A KR       
Sbjct:  87 TLWLGLHSDSLDIENILGVEVIPPYSKERVEEIMGALEGEISYTPPKYCA-KRIGGRRAY 145

Query: 178 ---------QLRIRTIYESKLLEYDPKRRLVLFWVSCEAGTYIRTLCVHLGLLLGVGGHM 228
                    +L I T+   +L         V F      G+YIR+L   +   LG  G +
Sbjct: 146 DMARNKEEVELPILTMRVGRLSLLHYTHPFVHFEAEVSKGSYIRSLGGMIASRLGCYGAL 205

Query: 229 QELRRVRSG 237
             L R+  G
Sbjct: 206 SSLERLSEG 214

emb|CAH90436.1| hypothetical protein [Pongo pygmaeus]
(169 aa)

Score: 46 bits (110), Expect: 0.00108759
Length: 95, Idn/Pos/Gap = 31/41/16 (32%/43%/16%)

Query:  72 SGVINLDKPANPSSHEVV----------------AWIKRILRVEKTGHSGTLDPQVTGCL 115
           SGV  + KP  P+S E++                 W KR  +  K GH GTLD    G L
Sbjct:  69 SGVFAVHKPKGPTSAELLNRLKEKLLAEAGMPSPEWTKRKKQTLKIGHGGTLDSAARGVL 128

Query: 116 IVCIERATRLVKSQQSAGKEYVAVLRLHGMRPELD 150
           +V I   T+++ S  S  K Y A+  L      LD
Sbjct: 129 VVGIGSGTKMLTSMLSGSKRYTAIGELGKATDTLD 163

emb|CAB62387.1| Maa2 protein [Chlamydomonas reinhardtii]
sp|Q9SMH4|RAA2_CHLRE Trans-splicing factor Raa2, chloroplast precursor
(410 aa)

Score: 45 bits (107), Expect: 0.00272311
Length: 77, Idn/Pos/Gap = 26/40/0 (33%/51%/0%)

Query:  68 EYIRSGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPQVTGCLIVCIERATRLVK 127
           E + +GV+ +DKP +    EVVA ++R    +K      LD + +G +++C   ATRL  
Sbjct: 131 EVLANGVLLVDKPPHWEVPEVVAAVQRATGADKVASVAPLDARASGLMLLCFGSATRLAP 190

Query: 128 SQQSAGKEYVAVLRLHG 144
             + A K Y   L L G
Sbjct: 191 RVERAAKRYTGTLVLGG 207

ref|NP_579681.1| iron-sulfur protein [Pyrococcus furiosus DSM 3638]
gb|AAL82076.1| iron-sulfur protein [Pyrococcus furiosus DSM 3638]
(641 aa)

Score: 45 bits (105), Expect: 0.00434499
Length: 98, Idn/Pos/Gap = 28/47/9 (28%/47%/9%)

Query: 282 KRIVIKDSCVNAVCYGAKLMLPGVLRYENDIECGEEVVIMTTKGEAVALAIAHMSTSEIA 341
           K ++I    V  V  GA ++  G+L  E  I+  EEV++++  GE V + IA    + + 
Sbjct: 143 KWVIIDKGAVEPVKKGANVLPVGILEAEESIKRNEEVIVVSEDGEVVGVGIAKKDYAGLV 202

Query: 342 SCDHGVVARIKRVVMERDLYPRRWGLGPVASRKKAMIQ 379
           S + G   ++KR         + WG G     +KA I+
Sbjct: 203 SKERGTGIKMKR---------KAWGSGKRVKDRKASIE 231

gb|EAA65250.1| hypothetical protein AN0072.2 [Aspergillus nidulans FGSC A4]
ref|XP_404209.1| hypothetical protein AN0072.2 [Aspergillus nidulans FGSC A4]
(392 aa)

Score: 44 bits (103), Expect: 0.0067053
Length: 94, Idn/Pos/Gap = 28/39/15 (29%/41%/15%)

Query: 100 KTGHSGTLDPQVTGCLIVCIERATRLVKSQQSAGKEYVAVLRLHGMRPELD--------- 150
           K GH GTLDP  TG L+  + + T+ +       K Y  V+         D         
Sbjct:  68 KIGHGGTLDPLATGVLVTGVGKGTKFLNDFLGCTKTYETVVIFGAETDSYDRLGKIVRRA 127

Query: 151 ------EATVRRAIETLTGPLYQRPPLISAVKRQ 178
                    V +A+E   G + QRPP+ SA+K Q
Sbjct: 128 PYEHITREAVEKALEQFRGKIMQRPPIFSALKVQ 161

gb|EAA22116.1| TruB family pseudouridylate synthase, putative [Plasmodium yoelii yoelii]
(172 aa)

Score: 43 bits (102), Expect: 0.00826056
Length: 85, Idn/Pos/Gap = 27/43/11 (31%/50%/12%)

Query:  66 IQEYIRSGVINLDKPANPSSHEVVAWIKRILR-----------VEKTGHSGTLDPQVTGC 114
           I + +  G +N+ KP    S +V   IK++L+             K GH GTLDP   G 
Sbjct:  58 IDDILYGGFLNIYKPVKLYSMKVCEKIKKVLKNYFININKNNIKIKVGHGGTLDPFAEGV 117

Query: 115 LIVCIERATRLVKSQQSAGKEYVAV 139
           L++ I+R T+ + +     K+Y+AV
Sbjct: 118 LMIGIQRGTKELSNFLKCYKQYLAV 142

Cyanidioschyzon merolae Genome Project