Cyanidioschyzon merolae Genome Project

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CMQ191C (482 aa)
by blastp 2.2.10 [Oct-19-2004] against nr [Apr-30-2005] (XML result)


ENSANGP00000015768 [Anopheles gambiae str. PEST]

hypothetical protein [Dictyostelium discoideum]

GA17736-PA [Drosophila pseudoobscura]

citrate synthase, mitochondrial [Dictyostelium discoideum]

CG3861-PB, isoform B [Drosophila melanogaster]

CG3861-PA, isoform A [Drosophila melanogaster]

CS protein [Homo sapiens]

PREDICTED: similar to citrate (si)-synthase (EC 4.1.3.7) precursor - pig [Canis familiaris]

citrate synthase [Homo sapiens]

citrate synthase [Homo sapiens]

similar to ENSANGP00000015768 [Apis mellifera]

mitochondrial citrate synthase precursor [Katsuwonus pelamis]

Cs-prov protein [Xenopus laevis]

mitochondrial citrate synthase precursor [Thunnus obesus]

citrate synthase [Sus scrofa]

Chain B, Citrate Synthase (E.C.4.1.3.7) - Oxaloacetate Complex

mitochondrial citrate synthase precursor [Xiphias gladius]

Citrate synthase [Danio rerio]

mitochondrial citrate synthase precursor [Tetrapturus audax]

Citrate Synthase (E.C.4.1.3.7) - (CoA, Citrate) Complex

citrate synthase-like protein [Mus musculus]

Chain B, Chicken Citrate Synthase Complex With Trifluoroacetonyl-Coa And Citrate

unnamed protein product [Tetraodon nigroviridis]

hypothetical protein LOC550067 [Xenopus tropicalis]

Citrate synthase-like protein [Mus musculus]

Chicken Citrate Synthase Complex With Nitromethylde-Coa And Malate

citrate synthase [Rattus norvegicus]

citrate synthase [Mus musculus]

CS protein [Homo sapiens]

PREDICTED: similar to citrate (si)-synthase (EC 4.1.3.7) precursor - pig [Bos taurus]

citrate synthase [Aspergillus niger]

citrate synthase precursor [Aspergillus niger]

hypothetical protein [Homo sapiens]

CISY_EMENI Citrate synthase, mitochondrial precursor [Aspergillus nidulans FGSC A4]

citrate synthase [Aspergillus nidulans]

Citrate synthase, mitochondrial

Hypothetical protein CBG09810 [Caenorhabditis briggsae]

Hypothetical protein T20G5.2 [Caenorhabditis elegans]

hypothetical protein CNBA0490 [Cryptococcus neoformans var. neoformans B-3501A]

mitochondrial citrate synthase [Podospora anserina]

CIT1 [Saccharomyces cerevisiae]

AAR004Cp [Ashbya gossypii ATCC 10895]

unknown [Schistosoma japonicum]

citrate synthase [Issatchenkia orientalis]

CIT1 [Saccharomyces bayanus]

unnamed protein product [Candida glabrata CBS138]

unnamed protein product [Saccharomyces cerevisiae]

unnamed protein product [Yarrowia lipolytica CLIB99]

At2g44350 [Arabidopsis thaliana]

citrate synthase [Arabidopsis thaliana]

SPAC6C3.04 [Schizosaccharomyces pombe]

mitochondrial citrate synthase [Neurospora crassa]

CIT1 [Saccharomyces castellii]

unnamed protein product [Kluyveromyces lactis NRRL Y-1140]

putative citrate synthase [Saccharomyces kluyveri]

CISY_NEUCR Citrate synthase, mitochondrial precursor [Gibberella zeae PH-1]

Citrate synthase, mitochondrial precursor

citrate synthase [Candida tropicalis]

citrate (si)-synthase (EC 4.1.3.7), mitochondrial - Neurospora crassa

citrate synthase [Oryza sativa]

hypothetical protein MG07202.4 [Magnaporthe grisea 70-15]

mitochondrial citrate synthase precursor [Citrus junos]

citrate synthase [Oryza sativa (japonica cultivar-group)]

Chain B, Citrate Synthase (E.C.4.1.3.7)

citrate (si)-synthase [Beta vulgaris subsp. vulgaris]

Citrate synthase, mitochondrial precursor

unnamed protein product [Debaryomyces hansenii CBS767]

citrate synthase [Prunus persica]

citrate synthase precursor

hypothetical protein CaO19.4393 [Candida albicans SC5314]

citrate synthase [Saccharomyces cerevisiae]

citrate synthase [Nicotiana tabacum]

citrate synthase-like protein [Arabidopsis thaliana]

Citrate synthase, mitochondrial precursor

citrate synthase [Oryza sativa (japonica cultivar-group)]

Citrate synthase, mitochondrial precursor, putative [Paramecium tetraurelia]

ethanolamine ammonia-lyase; mitochondrial citrate-synthase [Solanum tuberosum]

citrate synthase [Desulfuromonas palmitatis]

hypothetical protein MG02617.4 [Magnaporthe grisea 70-15]

unnamed protein product [Candida glabrata CBS138]

unnamed protein product [Yarrowia lipolytica CLIB99]

probable methylcitrate synthase [Neurospora crassa]

citrate synthase [Symbiobacterium thermophilum IAM 14863]

citrate synthase [Desulfuromonas acetoxidans]

conserved hypothetical protein [Gibberella zeae PH-1]

COG0372: Citrate synthase [Geobacter metallireducens GS-15]

citrate synthase [Geobacter sulfurreducens PCA]

citrate synthase [Pelobacter carbinolicus]

COG0372: Citrate synthase [Geobacter metallireducens GS-15]

CG14740-PA [Drosophila melanogaster]

hypothetical protein AN6650.2 [Aspergillus nidulans FGSC A4]

citrate synthase precursor [Tetrahymena thermophila]

hypothetical protein UM01627.1 [Ustilago maydis 521]

citrate (si)-synthase [Populus trichocarpa X Populus deltoides]

unnamed protein product [Kluyveromyces lactis NRRL Y-1140]

PREDICTED: similar to Citrate synthase, mitochondrial precursor [Pan troglodytes]

citrate synthetase [Arabidopsis thaliana]

similar to XM_053164 citrate synthase precursor in Homo sapiens [Schistosoma japonicum]

Cit3p [Saccharomyces cerevisiae]

GM05016p [Drosophila melanogaster]

unnamed protein product [Candida glabrata CBS138]

AGR002Wp [Ashbya gossypii ATCC 10895]

citrate synthase, mitochondrial precursor, putative [Plasmodium falciparum 3D7]

CIT3 [Saccharomyces castellii]

citrate synthase [Homo sapiens]

probable citrate synthase, mitochondrial precursor [Plasmodium yoelii yoelii]

citrate synthase, mitochondrial precursor, putative [Plasmodium berghei]

citrate synthase [Malonomonas rubra]

CIT3 [Saccharomyces kluyveri]

citrate synthase [Geobacter bemidjiensis]

CIT2 [Saccharomyces bayanus]

citrate synthase [Desulfuromonas acetexigens]

citrate synthase, mitochondrial precursor, putative [Plasmodium chabaudi]

citrate synthase [Sesbania rostrata]

PREDICTED: similar to citrate (si)-synthase (EC 4.1.3.7) precursor - pig [Canis familiaris]

similar to ENSANGP00000015768 [Apis mellifera]

citrate synthase [Pachycara brachycephalum]

putative citrate (si)-synthase [Parachlamydia sp. UWE25]

citrate synthase [Bos taurus]

PREDICTED: similar to citrate synthase [Rattus norvegicus]

citrate synthase [Zoarces viviparus]

hypothetical protein PC301067.00.0 [Plasmodium chabaudi]

COG0372: Citrate synthase [Cytophaga hutchinsonii]

putative citrate synthase [Nocardia farcinica IFM 10152]

citrate synthase [Corynebacterium diphtheriae NCTC 13129]

citrate (si)-synthase [Corynebacterium glutamicum]

At2g42790/F7D19.21 [Arabidopsis thaliana]

citrate synthase [Mycobacterium smegmatis]

COG0372: Citrate synthase [Bifidobacterium longum DJO10A]

citrate synthase 1 [Bifidobacterium longum NCC2705]

citrate synthase [Leifsonia xyli subsp. xyli str. CTCB07]

citrate synthase. [Streptomyces coelicolor A3(2)]

citrate synthase [Corynebacterium efficiens YS-314]

GltA2 [Mycobacterium avium subsp. paratuberculosis str. k10]

probable citrate synthase [Desulfotalea psychrophila LSv54]

citrate synthase [Francisella tularensis subsp. tularensis Schu 4]

citrate synthase 1 [Mycobacterium leprae TN]

At3g58750 [Arabidopsis thaliana]

citrate synthase [Rhodopirellula baltica SH 1]

citrate synthase 1 [Propionibacterium acnes KPA171202]

citrate synthase [Lactococcus lactis subsp. lactis Il1403]

Citrate synthase [Idiomarina loihiensis L2TR]

citrate synthase [Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130]

putative citrate synthase [Streptomyces avermitilis MA-4680]

Chain B, Citrate Synthase From Pyrococcus Furiosus

citrate synthase [Pyrococcus furiosus DSM 3638]

PROBABLE CITRATE SYNTHASE I GLTA2 [Mycobacterium tuberculosis H37Rv]

PROBABLE CITRATE SYNTHASE I GLTA2 [Mycobacterium bovis AF2122/97]

citrate synthase [Synechocystis sp. PCC 6803]

citrate synthase II [Bacillus clausii KSM-K16]

citrate synthase [Shigella flexneri 2a str. 301]

citrate (si)-synthase (EC 4.1.3.7) - Acetobacter aceti

citrate synthase [Escherichia coli O157:H7]

Citrate synthase [Escherichia coli CFT073]

citrate synthase [Escherichia coli O157:H7 EDL933]

citrate synthase [Erwinia carotovora subsp. atroseptica SCRI1043]

Chain B, Three Dimensional Structure Analysis Of The Type Ii Citrate Synthase From E.Coli

citrate synthase [Escherichia coli K12]

citrate synthase [Coxiella burnetii RSA 493]

citrate synthase [Photorhabdus luminescens subsp. laumondii TTO1]

citrate synthase GltA [Yersinia pseudotuberculosis IP 32953]

citrate synthase [Pyrobaculum aerophilum str. IM2]

citrate synthase [Xanthomonas axonopodis pv. citri str. 306]

putative Citrate synthase, glyoxysomal precursor (GCS) [Oryza sativa (japonica cultivar-group)]

citrate synthase [Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150]

COG0372: Citrate synthase [Azotobacter vinelandii]

citrate synthase

citrate (si)-synthase (EC 4.1.3.7) - Pseudomonas aeruginosa

citrate synthase [Xanthomonas campestris pv. campestris str. ATCC 33913]

citrate synthase [Wolbachia pipientis]

citrate synthase [Salmonella typhimurium LT2]

citrate synthase [Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67]

Chain B, Three Dimensional Structure Analysis Of The R109l Variant Of The Type Ii Citrate Synthase From E. Coli

citrate synthase [Acinetobacter sp. ADP1]

citrate synthase [Propionibacterium acnes KPA171202]

citrate synthase II [Bacillus subtilis subsp. subtilis str. 168]

Chain B, A Novel Nadh Allosteric Regulator Site Is Found On The Surface Of The Hexameric Type Ii Phe383ala Variant Of Citrate Synthase

COG0372: Citrate synthase [Brevibacterium linens BL2]

Citrate synthase, glyoxysomal precursor (GCS)

COG0372: Citrate synthase [Methylobacillus flagellatus KT]

citrate synthase [Streptococcus thermophilus CNRZ1066]

citrate synthase [Salmonella enterica subsp. enterica serovar Typhi Ty2]

COG0372: Citrate synthase [Pseudomonas aeruginosa UCBPP-PA14]

COG0372: Citrate synthase [Streptococcus thermophilus LMD-9]

citrate synthase II [Bacillus halodurans C-125]

citrate synthase [Lactococcus lactis subsp. lactis]

COG0372: Citrate synthase [Rubrobacter xylanophilus DSM 9941]

citrate synthase [Caulobacter crescentus CB15]

citrate synthase [Pseudomonas aeruginosa PAO1]

citrate synthase II [Bacillus licheniformis ATCC 14580]

citrate synthase [Xanthomonas oryzae pv. oryzae KACC10331]

COG0372: Citrate synthase [Trichodesmium erythraeum IMS101]

citrate synthase II

COG0372: Citrate synthase [Pseudomonas fluorescens PfO-1]

COG0372: Citrate synthase [Burkholderia cepacia R18194]

citrate synthaseII [Geobacillus kaustophilus HTA426]

COG0372: Citrate synthase [Microbulbifer degradans 2-40]

citrate synthase [Pseudomonas putida KT2440]

Citrate synthase [Gluconobacter oxydans 621H]

COG0372: Citrate synthase [Silicibacter sp. TM1040]

Citrate synthase [Nitrosomonas europaea ATCC 19718]

COG0372: Citrate synthase [Pseudomonas syringae pv. syringae B728a]

citrate synthase I [Pseudomonas syringae pv. tomato str. DC3000]

citrate synthase [Nostoc sp. PCC 7120]

citrate synthase I [Campylobacter upsaliensis RM3195]

citrate (si)-synthase (EC 4.1.3.7) - Acinetobacter anitratus

citrate synthase [Nostoc sp. PCC 7120]

COG0372: Citrate synthase [Burkholderia cepacia R1808]

citrate synthase [Burkholderia pseudomallei K96243]

citrate synthase [Thermotoga maritima MSB8]

COG0372: Citrate synthase [Burkholderia fungorum LB400]

COG0372: Citrate synthase [Nostoc punctiforme PCC 73102]

citrate synthase [Bacillus methanolicus]

putative methylcitrate synthase [Photobacterium profundum SS9]

COG0372: Citrate synthase [Ralstonia metallidurans CH34]

COG0372: Citrate synthase [Magnetococcus sp. MC-1]

COG0372: Citrate synthase [Xylella fastidiosa Dixon]

COG0372: Citrate synthase [Anabaena variabilis ATCC 29413]

citrate synthase [Ehrlichia equi]

citrate synthase [Anaplasma marginale]

citrate synthase [Campylobacter jejuni RM1221]

citrate synthase [Anaplasma phagocytophila]

citrate (si)-synthase [Chromobacterium violaceum ATCC 12472]

Citrate synthase [Sulfolobus solfataricus P2]

Citrate synthase [Wolbachia endosymbiont strain TRS of Brugia malayi]

citrate synthase [Wolbachia endosymbiont of Drosophila melanogaster]

citrate synthase [Thermosynechococcus elongatus BP-1]

hypothetical protein Bd0562 [Bdellovibrio bacteriovorus HD100]

citrate synthase III [Bacillus subtilis subsp. subtilis str. 168]

citrate synthase I [Campylobacter coli RM2228]

COG0372: Citrate synthase [Burkholderia fungorum LB400]

citrate synthase [Dictyostelium discoideum]

citrate synthase [Anaplasma phagocytophila]

citrate synthase [Mesorhizobium loti MAFF303099]

CITRATE SYNTHASE [Helicobacter pylori J99]

COG0372: Citrate synthase [Psychrobacter sp. 273-4]

citrate synthase [Xylella fastidiosa 9a5c]

COG0372: Citrate synthase [Rubrivivax gelatinosus PM1]

COG0372: Citrate synthase [Xylella fastidiosa Ann-1]

hypothetical citrate synthase [Sulfolobus tokodaii str. 7]

citrate synthase [Rickettsia sp. IO1]

COG0372: Citrate synthase [Novosphingobium aromaticivorans DSM 12444]

citrate synthase [Chlorobium limicola]

citrate synthase [Xylella fastidiosa Temecula1]

Citrate synthase [Vibrio vulnificus CMCP6]

Citrate synthase

putative citrate synthase [Neisseria gonorrhoeae FA 1090]

putative citrate synthase [Photobacterium profundum SS9]

hypothetical protein AGR_C_2572 [Agrobacterium tumefaciens str. C58]

citrate synthase [Vibrio cholerae O1 biovar eltor str. N16961]

COG0372: Citrate synthase [Ralstonia eutropha JMP134]

citrate synthase [Legionella pneumophila str. Paris]

hypothetical protein FG02352.1 [Gibberella zeae PH-1]

citrate synthase [Bacillus cereus G9241]

citrate synthase [Bacillus cereus ZK]

hypothetical protein lmo1567 [Listeria monocytogenes EGD-e]

citrate synthase [Deinococcus radiodurans]

citrate synthase citz [Bacillus anthracis str. 'Ames Ancestor']

citrate synthase [Rhodopseudomonas palustris CGA009]

citrate synthase [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]

citrate synthase [Vibrio parahaemolyticus RIMD 2210633]

citrate synthase [Rickettsia canadensis]

citrate synthase [Erythrobacter litoralis HTCC2594]

citrate synthase [Bordetella parapertussis 12822]

citrate synthase [Thermus thermophilus HB8]

citrate synthase [Thermus thermophilus]

citrate synthase [Thermus thermophilus HB27]

citrate synthase [Sulfolobus solfataricus]

citrate synthase [Rickettsia sp. IM1]

Citrate synthase [Prochlorococcus marinus subsp. marinus str. CCMP1375]

citrate synthase [Candidatus Rickettsia tarasevichiae]

COG0372: Citrate synthase [Rickettsia akari str. Hartford]

citrate synthase [Streptococcus mutans UA159]

citrate synthase [Ehrlichia ruminantium str. Welgevonden]

citrate synthase (gltA) [Helicobacter pylori 26695]

citrate synthase [Bordetella pertussis Tohama I]

Citrate synthase [Bacillus cereus ATCC 14579]

citrate synthase CitZ [Bacillus cereus ATCC 10987]

putative citrate synthase [Neisseria meningitidis Z2491]

citrate synthase

Citrate synthase [Prochlorococcus marinus subsp. pastoris str. CCMP1986]

citrate synthase [Rickettsia sibirica 246]

citrate synthase 2 [Thermoproteus tenax]

citrate synthase [Shewanella oneidensis MR-1]

COG0372: Citrate synthase [Rhodobacter sphaeroides 2.4.1]

COG0372: Citrate synthase [Ralstonia eutropha JMP134]

COG0372: Citrate synthase [Magnetospirillum magnetotacticum MS-1]

citrate synthase [Bradyrhizobium japonicum]

(R)-citric synthase.; Citrate condensing enzyme.; Citrate oxaloacetate-lyase [(pro-3S)-CH(2)COO(-)->acetyl-CoA].; Citrate oxaloacetate-lyase, CoA-acetylating.; Citrate synthase.; Citrate synthetase.; Citric synthase.; Citric-condensing enzyme.; Citrogenase.; Condensing enzyme.; Oxalacetic transacetase.; Oxaloacetate transacetase.; citrate (Si)-synthase [Rickettsia typhi str. Wilmington]

citrate synthase [Rickettsia sp. IRS 4]

citrate synthase [Bradyrhizobium japonicum USDA 110]

citrate synthase [EC:4.1.3.7] [Rickettsia conorii str. Malish 7]

citrate synthase [Listeria monocytogenes str. 4b F2365]

GltA protein [Mannheimia succiniciproducens MBEL55E]

citrate synthase [Bacteroides fragilis YCH46]

citrate synthase [Anaplasma centrale]

citrate synthase [Rickettsia sp. AT1]

citrate synthase [Methylococcus capsulatus str. Bath]

citrate synthase [Vibrio fischeri ES114]

COG0372: Citrate synthase [Rickettsia rickettsii]

citZ [Listeria innocua Clip11262]

citrate synthase (citZ) [Archaeoglobus fulgidus DSM 4304]

citrate (si)-synthase (EC 4.1.3.7) [validated] - Bacillus sp. (ATCC 55182)

CITRATE SYNTHASE (gltA) [Rickettsia prowazekii str. Madrid E]

citrate synthase [Israeli tick typhus rickettsia]

similar to Dictyostelium discoideum (Slime mold). Citrate synthase

citrate synthase [Rickettsia sp. HL-93]

citrate synthase [Rickettsia heilongjiangensis]

citrate synthase [Rickettsia heilongjiangii]

citrate synthase [Rickettsia sp. BJ-90]

citrate-synthase [Candidatus Rickettsia principis]

citrate synthase [Rickettsia sp. A-167]

citrate synthase [Rickettsia sp. California 2]

citrate synthase [Thermus aquaticus]

citrate synthase [Sinorhizobium fredii]

COG0372: Citrate synthase [Thiobacillus denitrificans ATCC 25259]

COG0372: Citrate synthase [Dechloromonas aromatica RCB]

methylcitrate synthase, putative [Pseudomonas putida KT2440]

citrate synthase [Rickettsia sp.]

citrate synthase [Bacteroides thetaiotaomicron VPI-5482]

citrate-synthase [Candidatus Rickettsia principis]

citrate synthase [Rickettsia amblyommii]

citrate synthase [Rickettsia sp. RpA4]

putative citrate synthase [Tetrahymena thermophila]

citrate synthase [Rickettsia heilongjiangensis]

CITRATE SYNTHASE PROTEIN [Sinorhizobium meliloti]

citrate synthase [Rickettsia sp. DaE100R]

citrate synthase [Bacillus clausii KSM-K16]

citrate synthase [Rickettsia sibirica]

citrate synthase [Rickettsia akari]

putative citrate synthase [uncultured bacterium]

citrate synthase [Rickettsia honei]

citrate synthase [Rickettsia rhipicephali]

citrate synthase [Rickettsia sp. COOPERI]

citrate synthase [Rickettsia sp.]

COG0372: Citrate synthase [Polaromonas sp. JS666]

citrate synthase [Rickettsia typhi]

citrate synthase [Rickettsia australis]

citrate synthase [Rickettsia conorii]

citrate synthase [Rickettsia sp. FLA1]

citrate synthase [Rickettsia montanensis]

citrate synthase [Rickettsia sp.]

citrate synthase II [Staphylococcus aureus subsp. aureus MSSA476]

COG0372: Citrate synthase [Rubrobacter xylanophilus DSM 9941]

citrate synthase [Rickettsia sp.]

COG0372: Citrate synthase [Streptococcus suis 89/1591]

citrate synthase II [Staphylococcus aureus subsp. aureus MRSA252]

citrate synthase [Ehrlichia risticii]

citrate synthase [Rhizobium tropici]

COG0372: Citrate synthase [Mesorhizobium sp. BNC1]

citrate synthase [Rickettsia sp. DnS28]

citrate synthase-like protein [Arabidopsis thaliana]

citrate synthase [Sinorhizobium meliloti]

PROBABLE CITRATE SYNTHASE PROTEIN [Ralstonia solanacearum]

citrate synthase [Azoarcus sp. EbN1]

citrate synthase [Rickettsia bellii]

citrate synthase [Rickettsia africae]

citrate synthase [Gloeobacter violaceus PCC 7421]

citrate synthase [Rickettsia sp.]

citrate synthase [Chlorobium tepidum TLS]

citrate synthase [Rickettsia rickettsii]

citrate synthase [Synechococcus sp. WH 8102]

Citrate synthase [Bartonella henselae str. Houston-1]

citrate synthase [Bacillus cereus ZK]

citrate synthase [Neorickettsia helminthoeca]

COG0372: Citrate synthase [Moorella thermoacetica ATCC 39073]

COG0372: Citrate synthase [Ferroplasma acidarmanus]

COG0372: Citrate synthase [Rhodospirillum rubrum]

citrate synthase [Rhizobium tropici]

COG0372: Citrate synthase [Haemophilus somnus 2336]

COG0372: Citrate synthase [Clostridium thermocellum ATCC 27405]

2-methylcitrate synthase [Coxiella burnetii RSA 493]

citrate synthase

citrate synthase [Rickettsia sp. DT1]

citrate synthase 2 [Pseudomonas aeruginosa PAO1]

citrate synthase I [Silicibacter pomeroyi DSS-3]

COG0372: Citrate synthase [Haemophilus somnus 129PT]

Citrate synthase [Prochlorococcus marinus str. MIT 9313]

Citrate synthase [Bartonella quintana str. Toulouse]

citrate synthase [Haloferax volcanii]

COG0372: Citrate synthase [Pseudomonas syringae pv. syringae B728a]

citrate synthase [Rickettsia sp.]

citrate synthase [Anaplasma platys]

citrate synthase mmgd [Bacillus anthracis str. 'Ames Ancestor']

citrate synthase [Erwinia carotovora subsp. atroseptica SCRI1043]

citrate synthase [Aeropyrum pernix K1]

citrate synthase [Synechococcus elongatus PCC 6301]

citrate synthase [Rickettsia bellii]

citrate synthase II [Oceanobacillus iheyensis HTE831]

2-methylcitrate synthase [Bacillus cereus G9241]

COG0372: Citrate synthase [Synechococcus elongatus PCC 7942]

2-methylcitrate synthase [Bacillus cereus ATCC 14579]

citrate synthase [male-killing Rickettsia from Adalia bipunctata]

citrate synthase [Anaplasma platys]

citrate synthase III [Bacillus licheniformis ATCC 14580]

citrate synthase [male-killing Rickettsia from Adalia decempunctata]

citrate synthase [Rickettsia sp. R300]

hypothetical protein Bd2511 [Bdellovibrio bacteriovorus HD100]

2-methylcitrate synthase [Pseudomonas syringae pv. tomato str. DC3000]

citrate synthase [male-killing Rickettsia from Adalia bipunctata]

citrate synthase [Staphylococcus epidermidis RP62A]

citrate synthase [male-killing Rickettsia from Adalia bipunctata]

COG0372: Citrate synthase [Magnetospirillum magnetotacticum MS-1]

hypothetical citrate synthase [Sulfolobus tokodaii str. 7]

citrate synthase II [Staphylococcus epidermidis ATCC 12228]

citrate synthase [Rickettsia bellii]

CITRATE SYNTHASE [Brucella melitensis 16M]

citrate synthase [Brucella suis 1330]

GltA, citrate synthase [Brucella abortus biovar 1 str. 9-941]

Citrate synthase [Idiomarina loihiensis L2TR]

citrate synthase III [Oceanobacillus iheyensis HTE831]

citrate synthase [Zymomonas mobilis subsp. mobilis ZM4]

methylcitrate synthase [Shewanella oneidensis MR-1]

COG0372: Citrate synthase [Chloroflexus aurantiacus]

citrate synthase III [Bacillus halodurans C-125]

GltA [Bartonella rattimassiliensis]

citrate synthase [Rickettsia aeschlimannii]

citrate synthase [Anaplasma platys]

2-methylcitrate synthase [Legionella pneumophila str. Lens]

citrate synthase [Rickettsia sp. RDa420]

citrate synthase [Ehrlichia sennetsu]

putative methylcitrate synthase [Photobacterium profundum SS9]

citrate synthase [Rickettsia sp. ARANHA]

citrate synthase [Ehrlichia muris]

citrate synthase [Rickettsia sp. Chad]

probable citrate (si)-synthase [Thermoplasma acidophilum DSM 1728]

2-methylcitrate synthase [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]

GltA [Bartonella phoceensis]

citrate synthase [Rickettsia marmionii]

2-methylcitrate synthase [Legionella pneumophila str. Paris]

citrate synthase [Rickettsia sp. RF2125]

citrate synthase [Ehrlichia sp. Yamaguchi]

citrate synthase II [Haloarcula marismortui ATCC 43049]

citrate synthase MmgD [Bacillus cereus ATCC 10987]

GltA [Pasteurella multocida subsp. multocida str. Pm70]

probable citrate synthase [Desulfotalea psychrophila LSv54]

hypothetical protein plu3138 [Photorhabdus luminescens subsp. laumondii TTO1]

citrate synthase [Picrophilus torridus DSM 9790]

citrate synthase 2 [Xanthomonas campestris pv. campestris str. ATCC 33913]

Citrate synthase [Methanosarcina mazei Go1]

citrate synthase [Ehrlichia chaffeensis]

citrate synthase [Ehrlichia canis]

COG0372: Citrate synthase [Pseudomonas fluorescens PfO-1]

citrate (si)-synthase [Methanosarcina acetivorans C2A]

methylcitrate synthase [Vibrio cholerae O1 biovar eltor str. N16961]

citrate synthase [Bartonella schoenbuchensis]

methylcitrate synthase (citrate synthase 2) [Acinetobacter sp. ADP1]

citrate synthase [Neisseria meningitidis Z2491]

COG0372: Citrate synthase [Methanosarcina barkeri str. fusaro]

citrate synthase [Bartonella schoenbuchensis]

citrate synthase [Rickettsia sp. Rf31]

citrate synthase [Thermoplasma acidophilum DSM 1728]

citrate synthase [Bartonella schoenbuchensis]

citrate synthase [Bartonella henselae subsp. arupensis]

COG0372: Citrate synthase [Ferroplasma acidarmanus]

citrate synthase 2 [Xanthomonas oryzae pv. oryzae KACC10331]

putative citrate synthase [Corynebacterium efficiens YS-314]

CITRATE SYNTHASE [Wolinella succinogenes DSM 1740]

citrate synthase I [Bacillus subtilis subsp. subtilis str. 168]

CitZ [Halobacterium sp. NRC-1]

COG0372: Citrate synthase [Rhodospirillum rubrum]

citrate synthase [Bartonella taylorii]

citrate synthase [Ehrlichia sp. EHt224]

citrate synthase [Helicobacter hepaticus ATCC 51449]

Cold-Active Citrate Synthase

citrate synthase [Antarctic bacterium DS2-3R]

citrate synthase [Bartonella sp.]

GltA [Bartonella rattimassiliensis]

Citrate synthase [Thermoplasma volcanium GSS1]

PrpC [Salmonella typhimurium]

putative citrate synthase [Acidithiobacillus ferrooxidans]

citrate synthase [Bartonella schoenbuchensis]

citrate synthase [Bartonella schoenbuchensis]

citrate synthase [Bartonella schoenbuchensis]

citrate synthase 2 [Xanthomonas axonopodis pv. citri str. 306]

METHYLCITRATE SYNTHASE [Corynebacterium glutamicum ATCC 13032]

Citrate synthase [Vibrio vulnificus CMCP6]

(METHYL)CITRATE SYNTHASE [Corynebacterium glutamicum ATCC 13032]

citrate synthase PrpC [Helicobacter hepaticus ATCC 51449]

Citrate synthase [Corynebacterium glutamicum ATCC 13032]

citrate synthase [Rickettsia sp. DmS1]

citrate synthase [Rickettsia slovaca]

citrate synthase [Bartonella sp.]

citrate synthase [Ehrlichia sp. ERm58]

CitA [Bacillus licheniformis ATCC 14580]

citrate synthase [Vibrio vulnificus YJ016]

putative citrate synthase [Neisseria gonorrhoeae FA 1090]

citrate synthase [Bartonella vinsonii]

2-methylcitrate synthase [Campylobacter coli RM2228]

citrate synthase [Bartonella doshiae]

2-methylcitrate synthase [Burkholderia sacchari]

citrate synthase [Bartonella sp.]

citrate synthase [Rickettsia sp. RDla440]

citrate synthase [Wolbachia endosymbiont of Drosophila simulans]

COG0372: Citrate synthase [Ralstonia metallidurans CH34]

citrate synthase [Bartonella sp.]

citrate synthase 1 [Thermoproteus tenax]

Citrate synthase

citrate synthase [Bartonella taylorii]

COG0372: Citrate synthase [Brevibacterium linens BL2]
gb|EAA00454.3| ENSANGP00000015768 [Anopheles gambiae str. PEST]
ref|XP_320478.2| ENSANGP00000015768 [Anopheles gambiae str. PEST]
(465 aa)

Score: 543 bits (1398), Expect: 6.01824e-153
Length: 434, Idn/Pos/Gap = 255/335/5 (58%/77%/1%)

Query:  35 STSSATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYETSLL  94
           + S +T L+  +  KI   + +V   R++ G   +   TV+  YGGMR +K +V ETS+L
Sbjct:  28 NASDSTDLKAVLTEKIPKEQERVKNFRKQHGNTKVGEVTVDMMYGGMRGIKGLVCETSVL  87

Query:  95 DPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRR 154
           DP EGIRFRG SIPECQ++LP+A P G++PLPEGL WLL+TG++P+++QV+++ ++   R
Sbjct:  88 DPDEGIRFRGLSIPECQQVLPKA-PGGQEPLPEGLFWLLITGDVPSKAQVDALSREWANR 146

Query: 155 AAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDAL 214
           AA+P  V+ +L+ +P   +HPM+Q S AV+ L HESK A+AY++G  KS +WEY  ED++
Sbjct: 147 AALPSHVVTMLNNMP-TSLHPMSQLSCAVTALNHESKFAKAYSEGVHKSKYWEYVYEDSM 205

Query: 215 TLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVL 274
            LIA+LP +AA IYRNT+  GK + A  I+   D      + LG+E  +F ELMRLYL +
Sbjct: 206 DLIAKLPVIAATIYRNTYRDGKGIGA--IDPKKDWSANFTKMLGYEDEKFTELMRLYLTI 263

Query: 275 HADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGN 334
           H+DHEGGNVSAH V LVGSALSDPYLSFAAG+NGLAGPLHGLANQEVL WL +++++LG+
Sbjct: 264 HSDHEGGNVSAHTVHLVGSALSDPYLSFAAGMNGLAGPLHGLANQEVLVWLQKLRKELGD 323

Query: 335 RPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSKL 394
              + + ++E  W+TL+ G V+PG+GHAVLR+TDPRYT QREFALKHLP+D +F LVS +
Sbjct: 324 NA-SEDKVKEFIWKTLKSGQVVPGYGHAVLRKTDPRYTCQREFALKHLPNDPLFGLVSNI 382

Query: 395 YEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDR 454
           Y+VVP +L E GKVKNPWPNVD HSG+LL+YYGL E N+YTVLFGVSRALG L+SLVWDR
Sbjct: 383 YKVVPPILTELGKVKNPWPNVDAHSGVLLQYYGLKEMNYYTVLFGVSRALGVLASLVWDR 442

Query: 455 ALGLPIERPKSVTT 468
           ALGLPIERPKS++T
Sbjct: 443 ALGLPIERPKSMST 456


gb|AAO52260.1| hypothetical protein [Dictyostelium discoideum]
(460 aa)

Score: 541 bits (1393), Expect: 2.01789e-152
Length: 435, Idn/Pos/Gap = 261/326/4 (60%/74%/0%)

Query:  37 SSATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYETSLLDP  96
           S+  +L+E +   I     QV +++   G++++  CTV QAYGGMRS+K++V ETS LDP
Sbjct:  19 STEPTLKERLVQIIPGKIEQVKQLKTEHGDKIIGTCTVAQAYGGMRSVKSLVTETSSLDP  78

Query:  97 QEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAA 156
           +EGIRFRG +IPECQ  LP+A P G +PLPEG+LWLLLTGE+PTESQV+++ +DL +RA 
Sbjct:  79 EEGIRFRGLTIPECQEKLPKA-PGGAEPLPEGILWLLLTGEVPTESQVKTLSKDLAKRAG 137

Query: 157 VPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTL 216
           +P  V  ++   P E+MHPM+Q + A+  LQ ESK  +AY  G  K  +WE  LED+L +
Sbjct: 138 LPKHVTSMIKAFP-EQMHPMSQLAAAILALQGESKFVKAYNDGVKKDKYWESTLEDSLDV 196

Query: 217 IARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVLHA 276
           IA+LP VAA IY+NT+   K     KI++  D      R LG+   +FDELMRLYL +H 
Sbjct: 197 IAKLPEVAALIYQNTYK--KSDITHKIDENLDWSANFNRMLGYTSKDFDELMRLYLTIHT 254

Query: 277 DHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRP 336
           DHEGGNVSAH   LVGSALSD YLS +AG+ GLAGPLHGLANQEVL W ++++EKLGN+ 
Sbjct: 255 DHEGGNVSAHTTHLVGSALSDSYLSLSAGMCGLAGPLHGLANQEVLSWTMKLQEKLGNKE 314

Query: 337 MTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSKLYE 396
           ++ E L E  WE L  G V+PGFGHAVLR+TDPRYT QREFALKHLP D +F+LVS++YE
Sbjct: 315 VSNEVLSEAIWEGLNAGRVVPGFGHAVLRKTDPRYTCQREFALKHLPQDPLFKLVSQIYE 374

Query: 397 VVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRAL 456
           VVP +L + GK KNP+PNVD HSG LL+YYGL E NFYTVLFGVSRA+G LSSLVWDR L
Sbjct: 375 VVPDILTKHGKTKNPYPNVDAHSGCLLQYYGLKEHNFYTVLFGVSRAIGVLSSLVWDRIL 434

Query: 457 GLPIERPKSVTTQWI 471
           G PIERPKSVTT+WI
Sbjct: 435 GHPIERPKSVTTEWI 449


gb|EAL32663.1| GA17736-PA [Drosophila pseudoobscura]
(452 aa)

Score: 541 bits (1393), Expect: 2.23039e-152
Length: 447, Idn/Pos/Gap = 261/340/6 (58%/76%/1%)

Query:  31 VRALSTSSATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYE  90
           VR +S +   SL++ + +K+   + +V   R++ G   L   T++  YGGMR +KA+V E
Sbjct:  12 VRQIS-ADGRSLRDVLTAKVPAEQERVKNFRKQHGATKLGETTIDMMYGGMRGIKALVTE  70

Query:  91 TSLLDPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQD 150
           TS+LD  EGIRFRG SIPECQ++LP A P G +PLPEGL WLLLTGE+PT+SQV+ + ++
Sbjct:  71 TSVLDADEGIRFRGLSIPECQKVLP-AAPGGTEPLPEGLFWLLLTGEVPTQSQVQQLSRE 129

Query: 151 LKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCL 210
              RAA+P  V+ +L+ +P   +HPM+Q + AV+ L H+SK A+AY++G  KS +WEY  
Sbjct: 130 WAERAALPQHVVTMLNNMP-TSLHPMSQLAAAVTALNHDSKFAKAYSEGVHKSKYWEYVY 188

Query: 211 EDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRL 270
           ED++ LIA+LP VAA IY NT+ GGK   +  ++   D      + LG++  +F ELMRL
Sbjct: 189 EDSMDLIAKLPVVAATIYCNTYRGGKG--SRSVDSSLDWSANFVKMLGYDNAQFTELMRL 246

Query: 271 YLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKE 330
           YL +H+DHEGGNVSAH V LVGSALSDPYLSFAAG+NGLAGPLHGLANQEVL WL ++++
Sbjct: 247 YLTIHSDHEGGNVSAHTVHLVGSALSDPYLSFAAGMNGLAGPLHGLANQEVLVWLRKLQK 306

Query: 331 KLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQL 390
           + GN P + E L++  W+TL+ G V+PG+GHAVLR+TDPRYT QREFALKHLP DE+FQL
Sbjct: 307 EAGNNP-SEEQLKDYIWKTLKSGQVVPGYGHAVLRKTDPRYTCQREFALKHLPEDELFQL 365

Query: 391 VSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSL 450
           VSK+Y+VVP +L E GKVKNPWPNVD HSG+LL+YYG+ E N+YTVLFGVSRALG L+SL
Sbjct: 366 VSKIYKVVPPILTETGKVKNPWPNVDAHSGVLLQYYGMKEMNYYTVLFGVSRALGVLASL 425

Query: 451 VWDRALGLPIERPKSVTTQWIREHFEK 477
           VWDRALGLPIERPKS +T  + +  +K
Sbjct: 426 VWDRALGLPIERPKSFSTDLLVKMVQK 452


gb|EAL69936.1| citrate synthase, mitochondrial [Dictyostelium discoideum]
(460 aa)

Score: 540 bits (1391), Expect: 3.64902e-152
Length: 438, Idn/Pos/Gap = 261/327/4 (59%/74%/0%)

Query:  37 SSATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYETSLLDP  96
           S+  +L+E +   I     QV +++   G++++  CTV QAYGGMRS+K++V ETS LDP
Sbjct:  19 STEPTLKERLVQIIPGKIEQVKQLKTEHGDKIIGTCTVAQAYGGMRSVKSLVTETSSLDP  78

Query:  97 QEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAA 156
           +EGIRFRG +IPECQ  LP+A P G +PLPEG+LWLLLTGE+PTESQV+++ +DL +RA 
Sbjct:  79 EEGIRFRGLTIPECQEKLPKA-PGGAEPLPEGILWLLLTGEVPTESQVKTLSKDLAKRAG 137

Query: 157 VPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTL 216
           +P  V  ++   P E+MHPM+Q + A+  LQ ESK  +AY  G  K  +WE  LED+L +
Sbjct: 138 LPKHVTSMIKAFP-EQMHPMSQLAAAILALQGESKFVKAYNDGVKKDKYWESTLEDSLDV 196

Query: 217 IARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVLHA 276
           IA+LP VAA IY+NT+   K     KI++  D      R LG+   +FDELMRLYL +H 
Sbjct: 197 IAKLPEVAALIYQNTYK--KSDITHKIDENLDWSANFNRMLGYTSKDFDELMRLYLTIHT 254

Query: 277 DHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRP 336
           DHEGGNVSAH   LVGSALSD YLS +AG+ GLAGPLHGLANQEVL W ++++EKLGN+ 
Sbjct: 255 DHEGGNVSAHTTHLVGSALSDSYLSLSAGMCGLAGPLHGLANQEVLSWTMKLQEKLGNKE 314

Query: 337 MTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSKLYE 396
           ++ E L E  WE L  G V+PGFGHAVLR+TDPRYT QREFALKHLP D +F+LVS++YE
Sbjct: 315 VSNEVLSEAIWEGLNAGRVVPGFGHAVLRKTDPRYTCQREFALKHLPQDPLFKLVSQIYE 374

Query: 397 VVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRAL 456
           VVP +L + GK KNP+PNVD HSG LL+YYGL E NFYTVLFGVSRA+G LSSLVWDR L
Sbjct: 375 VVPDILTKHGKTKNPYPNVDAHSGCLLQYYGLKEHNFYTVLFGVSRAIGVLSSLVWDRIL 434

Query: 457 GLPIERPKSVTTQWIREH 474
           G PIERPKSVTT+WI  +
Sbjct: 435 GHPIERPKSVTTEWISSY 452


ref|NP_727091.1| CG3861-PB, isoform B [Drosophila melanogaster]
gb|AAN09169.1| CG3861-PB, isoform B [Drosophila melanogaster]
gb|AAL90056.1| AT12538p [Drosophila melanogaster]
(522 aa)

Score: 540 bits (1390), Expect: 5.09474e-152
Length: 464, Idn/Pos/Gap = 265/342/9 (57%/73%/1%)

Query:  14 DLRRAEKSWPSDVWKRAVRALSTSSATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACT  73
           D++ A+K      + R + A       SL++ + +K+   + +V   R++ G   +   T
Sbjct:  68 DMQDAQKLPNVGAYVRMIAA----DGKSLRDVLAAKVPQEQERVKNFRKQHGATKMGETT 123

Query:  74 VNQAYGGMRSLKAMVYETSLLDPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLL 133
           ++  YGGMR +KA+V ETS+LD  EGIRFRG SIPECQ++LP A   G +PLPEGL WLL
Sbjct: 124 IDMMYGGMRGIKALVTETSVLDADEGIRFRGLSIPECQKVLPAAD-GGTEPLPEGLFWLL 182

Query: 134 LTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMA 193
           LTGE+PT+SQV+ + ++   RAA+P  V+ +L+ +P   +HPM+QF+ AV+ L H+SK A
Sbjct: 183 LTGEVPTKSQVQQLSREWAERAALPQHVVTMLNNMP-TTLHPMSQFAAAVTALNHDSKFA 241

Query: 194 EAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRL 253
           +AY+ G  KS +WEY  ED++ LIA+LP VAA IY NT+ GGK   +  I+   D     
Sbjct: 242 KAYSDGVHKSKYWEYVYEDSMDLIAKLPVVAATIYCNTYRGGKG--SRSIDSSLDWSANF 299

Query: 254 ARSLGFELNEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPL 313
            + LG++   F ELMRLYL +H+DHEGGNVSAH V LVGSALSDPYLSFAAGLNGLAGPL
Sbjct: 300 VKMLGYDNAPFTELMRLYLTIHSDHEGGNVSAHTVHLVGSALSDPYLSFAAGLNGLAGPL 359

Query: 314 HGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTA 373
           HGLANQEVL WL +++++ GN P + E L+E  W+TL+ G V+PG+GHAVLR+TDPRYT 
Sbjct: 360 HGLANQEVLVWLRKLQKEAGNNP-SEEQLKEYIWKTLKSGQVVPGYGHAVLRKTDPRYTC 418

Query: 374 QREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNF 433
           QREFALKHLP DE FQLVSK+Y+VVP +L E GKVKNPWPNVD HSG+LL+YYG+ E N+
Sbjct: 419 QREFALKHLPEDETFQLVSKIYKVVPPILTETGKVKNPWPNVDAHSGVLLQYYGMKEMNY 478

Query: 434 YTVLFGVSRALGTLSSLVWDRALGLPIERPKSVTTQWIREHFEK 477
           YTVLFGVSRALG L+SLVWDRALGLPIERPKS +T  + +  +K
Sbjct: 479 YTVLFGVSRALGVLASLVWDRALGLPIERPKSFSTDLLVKMVQK 522


ref|NP_572319.2| CG3861-PA, isoform A [Drosophila melanogaster]
gb|AAF46159.1| CG3861-PA, isoform A [Drosophila melanogaster]
(464 aa)

Score: 538 bits (1387), Expect: 9.93148e-152
Length: 465, Idn/Pos/Gap = 266/341/9 (57%/73%/1%)

Query:  13 RDLRRAEKSWPSDVWKRAVRALSTSSATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDAC  72
           R L  A+K      + R + A       SL++ + +K+   + +V   R++ G   +   
Sbjct:   9 RKLSEAQKLPNVGAYVRMIAA----DGKSLRDVLAAKVPQEQERVKNFRKQHGATKMGET  64

Query:  73 TVNQAYGGMRSLKAMVYETSLLDPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWL 132
           T++  YGGMR +KA+V ETS+LD  EGIRFRG SIPECQ++LP A   G +PLPEGL WL
Sbjct:  65 TIDMMYGGMRGIKALVTETSVLDADEGIRFRGLSIPECQKVLPAAD-GGTEPLPEGLFWL 123

Query: 133 LLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKM 192
           LLTGE+PT+SQV+ + ++   RAA+P  V+ +L+ +P   +HPM+QF+ AV+ L H+SK 
Sbjct: 124 LLTGEVPTKSQVQQLSREWAERAALPQHVVTMLNNMP-TTLHPMSQFAAAVTALNHDSKF 182

Query: 193 AEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMR 252
           A+AY+ G  KS +WEY  ED++ LIA+LP VAA IY NT+ GGK   +  I+   D    
Sbjct: 183 AKAYSDGVHKSKYWEYVYEDSMDLIAKLPVVAATIYCNTYRGGKG--SRSIDSSLDWSAN 240

Query: 253 LARSLGFELNEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGP 312
             + LG++   F ELMRLYL +H+DHEGGNVSAH V LVGSALSDPYLSFAAGLNGLAGP
Sbjct: 241 FVKMLGYDNAPFTELMRLYLTIHSDHEGGNVSAHTVHLVGSALSDPYLSFAAGLNGLAGP 300

Query: 313 LHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYT 372
           LHGLANQEVL WL +++++ GN P + E L+E  W+TL+ G V+PG+GHAVLR+TDPRYT
Sbjct: 301 LHGLANQEVLVWLRKLQKEAGNNP-SEEQLKEYIWKTLKSGQVVPGYGHAVLRKTDPRYT 359

Query: 373 AQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESN 432
            QREFALKHLP DE FQLVSK+Y+VVP +L E GKVKNPWPNVD HSG+LL+YYG+ E N
Sbjct: 360 CQREFALKHLPEDETFQLVSKIYKVVPPILTETGKVKNPWPNVDAHSGVLLQYYGMKEMN 419

Query: 433 FYTVLFGVSRALGTLSSLVWDRALGLPIERPKSVTTQWIREHFEK 477
           +YTVLFGVSRALG L+SLVWDRALGLPIERPKS +T  + +  +K
Sbjct: 420 YYTVLFGVSRALGVLASLVWDRALGLPIERPKSFSTDLLVKMVQK 464


gb|AAH10106.1| CS protein [Homo sapiens]
gb|AAH72016.1| Citrate synthase, precursor, isoform a [Homo sapiens]
dbj|BAC11314.1| unnamed protein product [Homo sapiens]
ref|NP_004068.2| citrate synthase precursor, isoform a [Homo sapiens]
sp|O75390|CISY_HUMAN Citrate synthase, mitochondrial precursor
(466 aa)

Score: 535 bits (1378), Expect: 1.26539e-150
Length: 445, Idn/Pos/Gap = 253/334/5 (56%/75%/1%)

Query:  35 STSSATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYETSLL  94
           +++S+T+L++ +   I   +A++   R++ G+ V+   TV+  YGGMR +K +VYETS+L
Sbjct:  26 ASASSTNLKDILADLIPKEQARIKTFRQQHGKTVVGQITVDMMYGGMRGMKGLVYETSVL  85

Query:  95 DPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRR 154
           DP EGIRFRGFSIPECQ+LLP+AK  GE+PLPEGL WLL+TG IPTE QV  + ++  +R
Sbjct:  86 DPDEGIRFRGFSIPECQKLLPKAK-GGEEPLPEGLFWLLVTGHIPTEEQVSWLSKEWAKR 144

Query: 155 AAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDAL 214
           AA+P  V+ +LD  P   +HPM+Q S AV+ L  ES  A AYAQG  ++ +WE   ED++
Sbjct: 145 AALPSHVVTMLDNFP-TNLHPMSQLSAAVTALNSESNFARAYAQGISRTKYWELIYEDSM 203

Query: 215 TLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVL 274
            LIA+LP VAA+IYRN +  G  + A  I+   D        LG+  ++F EL RLYL +
Sbjct: 204 DLIAKLPCVAAKIYRNLYREGSGIGA--IDSNLDWSHNFTNMLGYTDHQFTELTRLYLTI 261

Query: 275 HADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGN 334
           H+DHEGGNVSAH   LVGSALSDPYLSFAA +NGLAGPLHGLANQEVL WL Q+++++G 
Sbjct: 262 HSDHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPLHGLANQEVLVWLTQLQKEVG- 320

Query: 335 RPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSKL 394
           + ++ E LR+  W TL  G V+PG+GHAVLR+TDPRYT QREFALKHLP+D MF+LV++L
Sbjct: 321 KDVSDEKLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYTCQREFALKHLPNDPMFKLVAQL 380

Query: 395 YEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDR 454
           Y++VP VL EQGK KNPWPNVD HSG+LL+YYG+ E N+YTVLFGVSRALG L+ L+W R
Sbjct: 381 YKIVPNVLLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLIWSR 440

Query: 455 ALGLPIERPKSVTTQWIREHFEKRS 479
           ALG P+ERPKS++T+ + +  + +S
Sbjct: 441 ALGFPLERPKSMSTEGLMKFVDSKS 465


ref|XP_531634.1| PREDICTED: similar to citrate (si)-synthase (EC 4.1.3.7) precursor - pig [Canis familiaris]
(602 aa)

Score: 534 bits (1376), Expect: 1.95279e-150
Length: 463, Idn/Pos/Gap = 258/337/6 (55%/72%/1%)

Query:  17 RAEKSWPSDVWKRAVRALSTSSATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQ  76
           R   +W +     A R  S SS T+L++ +   I   +A++   R++ G+ V+   TV+ 
Sbjct: 145 RIGGAWNASCLVLAARHASASS-TNLKDILADLIPKEQARIKTFRQQHGKTVVGQITVDM 203

Query:  77 AYGGMRSLKAMVYETSLLDPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTG 136
            YGGMR +K +VYETS+LDP EGIRFRG+SIPECQ+LLP+AK  GE+PLPEGL WLL+TG
Sbjct: 204 MYGGMRGMKGLVYETSVLDPDEGIRFRGYSIPECQKLLPKAK-GGEEPLPEGLFWLLVTG 262

Query: 137 EIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAY 196
           +IPTE QV  + ++  +RAA+P  V+ +LD  P   +HPM+Q S A++ L  ES  A AY
Sbjct: 263 QIPTEEQVSWLSKEWAKRAALPSHVVTMLDNFP-TNLHPMSQLSAAITALNSESNFARAY 321

Query: 197 AQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARS 256
           A+G  ++ +WE   ED + LIA+LP VAA+IYRN +  G  + A  I+   D        
Sbjct: 322 AEGINRTKYWELIYEDCMDLIAKLPCVAAKIYRNLYREGSSIGA--IDSKLDWSHNFTNM 379

Query: 257 LGFELNEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGL 316
           LG+   +F ELMRLYL +H+DHEGGNVSAH   LVGSALSDPYLSFAA +NGLAGPLHGL
Sbjct: 380 LGYTDAQFTELMRLYLTIHSDHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPLHGL 439

Query: 317 ANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQRE 376
           ANQEVL WL Q+++++G + ++ E LR+  W TL  G V+PG+GHAVLR+TDPRYT QRE
Sbjct: 440 ANQEVLVWLTQLQKEVG-KDVSDEKLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYTCQRE 498

Query: 377 FALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTV 436
           FALKHLPHD MF+LV++LY++VP VL EQGK KNPWPNVD HSG+LL+YYG+ E N+YTV
Sbjct: 499 FALKHLPHDSMFKLVAQLYKIVPNVLLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYYTV 558

Query: 437 LFGVSRALGTLSSLVWDRALGLPIERPKSVTTQWIREHFEKRS 479
           LFGVSRALG L+ L+W RALG P+ERPKS++T  + +  + +S
Sbjct: 559 LFGVSRALGVLAQLIWSRALGFPLERPKSMSTDGLMKFVDSKS 601


gb|AAC25560.1| citrate synthase [Homo sapiens]
(466 aa)

Score: 534 bits (1375), Expect: 2.34625e-150
Length: 445, Idn/Pos/Gap = 253/336/5 (56%/75%/1%)

Query:  35 STSSATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYETSLL  94
           +++S+T+L++ +   I   +A++   R++ G+ V+   TV+  YGGMR +K +VYETS+L
Sbjct:  26 ASASSTNLKDILADLIPKEQARIKTFRQQHGKTVVGQITVDMMYGGMRGMKGLVYETSVL  85

Query:  95 DPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRR 154
           DP EGIRFRGFSIPECQ+LLP+AK  GE+PLPEGL WLL+TG IPTE QV  + ++  +R
Sbjct:  86 DPDEGIRFRGFSIPECQKLLPKAK-GGEEPLPEGLFWLLVTGCIPTEEQVSWLSKEWAKR 144

Query: 155 AAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDAL 214
           AA+P  V+ +LD  P   +HPM+Q S AV+ L  ES  A+AYA+G  ++ +WE   ED++
Sbjct: 145 AALPSHVVTMLDNFP-TNLHPMSQLSAAVTALNSESNFAQAYARGISRTKYWELIYEDSV 203

Query: 215 TLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVL 274
            LIA+LP VAA+IYRN +  G  + A  I+   D        LG+  ++F ELMRLYL +
Sbjct: 204 DLIAKLPCVAAKIYRNLYWEGSGIGA--IDSNLDWSHNFTNMLGYTDHQFTELMRLYLTI 261

Query: 275 HADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGN 334
           H+DHEGGNVSAH   LVGSALSDPYLSFAA +NGLAGPLHGLANQEVL WL Q+++++G 
Sbjct: 262 HSDHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPLHGLANQEVLVWLTQLQKEVG- 320

Query: 335 RPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSKL 394
           + ++ E LR+  W TL  G V+PG+GHAVLR+TDPRYT QREFALKHLP+D MF+LV++L
Sbjct: 321 KDVSDEKLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYTCQREFALKHLPNDPMFKLVAQL 380

Query: 395 YEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDR 454
           Y++VP VL EQGK KNPWPNVD HSG+LL+YYG+ E N+YTVLFGVSRALG L+ L+W R
Sbjct: 381 YKIVPNVLLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLIWSR 440

Query: 455 ALGLPIERPKSVTTQWIREHFEKRS 479
           ALG P+ERPKS++T+ + +  + +S
Sbjct: 441 ALGFPLERPKSMSTEGLMKFVDSKS 465


gb|AAQ13428.1| citrate synthase [Homo sapiens]
(466 aa)

Score: 533 bits (1374), Expect: 3.444e-150
Length: 445, Idn/Pos/Gap = 252/333/5 (56%/74%/1%)

Query:  35 STSSATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYETSLL  94
           +++S+T+L++ +   I   +A++   R++ G+ V+   TV+  YGGMR +K +VYETS+L
Sbjct:  26 ASASSTNLKDILADLIPKEQARIKTFRQQHGKTVVGQITVDMMYGGMRGMKGLVYETSVL  85

Query:  95 DPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRR 154
           DP EGIRFRGFSIPECQ+LLP+AK  GE+PLPEGL WLL+TG IPTE QV  + ++  +R
Sbjct:  86 DPDEGIRFRGFSIPECQKLLPKAK-GGEEPLPEGLFWLLVTGHIPTEEQVSWLSKEWAKR 144

Query: 155 AAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDAL 214
           AA+P  V+ +LD  P   +HPM+Q S AV+ L  ES  A AYAQG  ++ +WE   ED++
Sbjct: 145 AALPSHVVTMLDNFP-TNLHPMSQLSAAVTALNSESNFARAYAQGISRTKYWELIYEDSM 203

Query: 215 TLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVL 274
            LIA+LP VAA+IYRN +  G  + A  I+   D        LG+  ++F EL RLYL +
Sbjct: 204 DLIAKLPCVAAKIYRNLYREGSGIGA--IDSNLDWSHNFTNMLGYTDHQFTELTRLYLTI 261

Query: 275 HADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGN 334
           H+DHEGGNVSAH   LVGSA SDPYLSFAA +NGLAGPLHGLANQEVL WL Q+++++G 
Sbjct: 262 HSDHEGGNVSAHTSHLVGSAFSDPYLSFAAAMNGLAGPLHGLANQEVLVWLTQLQKEVG- 320

Query: 335 RPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSKL 394
           + ++ E LR+  W TL  G V+PG+GHAVLR+TDPRYT QREFALKHLP+D MF+LV++L
Sbjct: 321 KDVSDEKLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYTCQREFALKHLPNDPMFKLVAQL 380

Query: 395 YEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDR 454
           Y++VP VL EQGK KNPWPNVD HSG+LL+YYG+ E N+YTVLFGVSRALG L+ L+W R
Sbjct: 381 YKIVPNVLLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLIWSR 440

Query: 455 ALGLPIERPKSVTTQWIREHFEKRS 479
           ALG P+ERPKS++T+ + +  + +S
Sbjct: 441 ALGFPLERPKSMSTEGLMKFVDSKS 465


ref|XP_393545.1| similar to ENSANGP00000015768 [Apis mellifera]
(902 aa)

Score: 533 bits (1372), Expect: 5.63453e-150
Length: 439, Idn/Pos/Gap = 248/328/7 (56%/74%/1%)

Query:  31 VRALSTSSATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYE  90
           +R+LS SS T L++ +  KI      V + R+  G  V+   TV+  YGGMR +K +++E
Sbjct: 463 LRSLSDSS-TDLKKILAEKIPKHLEVVKKFRKEHGSAVVGEVTVDMMYGGMRGIKGLLWE 521

Query:  91 TSLLDPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQD 150
            S+LDP+EGIRFRG SIPECQ++LP+AK  G +PLPEGL WLL+TG++P   QVE++ ++
Sbjct: 522 PSVLDPEEGIRFRGKSIPECQKILPKAK-DGSEPLPEGLFWLLITGDVPNNKQVETISKE 580

Query: 151 LKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCL 210
              R+ +P  V++ L   P + +HPMTQFS A+++L  ES+  +AY +G  KS +WEY  
Sbjct: 581 WASRSKLPEHVVKTLKNFP-KSLHPMTQFSAAITILNSESEFVKAYNKGVHKSKYWEYVY 639

Query: 211 EDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRL 270
           ED + LIA+LP+VAA IYRNT+  G  V    ++   D     +R LG+E  +F EL+RL
Sbjct: 640 EDIMNLIAKLPSVAAIIYRNTYKDGNTV---SVDSSKDWAWNFSRMLGYEDPQFTELLRL 696

Query: 271 YLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKE 330
           YL +HADHEGGNVSAH   LVGSALSD YLSFAAG+NGLAGPLHGLANQEVL WL ++++
Sbjct: 697 YLSIHADHEGGNVSAHTTHLVGSALSDAYLSFAAGMNGLAGPLHGLANQEVLIWLEKVQK 756

Query: 331 KLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQL 390
           ++G+ P + E + E    TL+ G V+PG+GHAVLR+TDPRY  QREFALKHLP D++F+L
Sbjct: 757 EIGDSP-SDEKVAEFVRNTLKSGQVVPGYGHAVLRKTDPRYICQREFALKHLPDDKLFKL 815

Query: 391 VSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSL 450
           VS++++VVP +L+E GKVKNPWPNVD HSG+LL+YYG+ E N+YTVLFGVSRALG LSSL
Sbjct: 816 VSQVFKVVPPILQETGKVKNPWPNVDAHSGVLLQYYGMKEMNYYTVLFGVSRALGVLSSL 875

Query: 451 VWDRALGLPIERPKSVTTQ 469
           VW R LG PIERPKS++T+
Sbjct: 876 VWSRGLGFPIERPKSLSTE 894


gb|AAR98860.1| mitochondrial citrate synthase precursor [Katsuwonus pelamis]
(469 aa)

Score: 531 bits (1369), Expect: 1.18403e-149
Length: 434, Idn/Pos/Gap = 245/331/5 (56%/76%/1%)

Query:  35 STSSATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYETSLL  94
           +++S T+L++ +   I   ++++   ++++G+  +   TV+  YGGMR +K +VYETS+L
Sbjct:  29 ASASTTNLKDVLSDLIPKEQSRIKNFKQQYGKTNIGQITVDMVYGGMRGMKGLVYETSVL  88

Query:  95 DPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRR 154
           DP+EGIRFRG+SIPECQ+LLP+A P GE+PLPEGL WLL+TG++PTE QV+ V ++  +R
Sbjct:  89 DPEEGIRFRGYSIPECQKLLPKA-PGGEEPLPEGLFWLLVTGQVPTEEQVKWVSKEWAKR 147

Query: 155 AAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDAL 214
           AA+P  V+ +LD  P   +HPM+QFS A++ L  ES  A AY++G  K+ +WE+  ED++
Sbjct: 148 AALPSHVVTMLDNFP-TNLHPMSQFSAAITALNSESSFARAYSEGVHKTKYWEFVYEDSM 206

Query: 215 TLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVL 274
            LIA+LP +AA+IYRN +  G  + A  I+   D        LG+   +F ELMRLYL +
Sbjct: 207 DLIAKLPCIAAKIYRNLYREGSSIGA--IDSNLDWSHNFTNMLGYSEAQFTELMRLYLTI 264

Query: 275 HADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGN 334
           H+DHEGGNVSAH   LVGSALSDPYLSF+A +NGLAGPLHGLANQEVL WL  +++++G 
Sbjct: 265 HSDHEGGNVSAHTSHLVGSALSDPYLSFSAAMNGLAGPLHGLANQEVLVWLTALQKEMGG 324

Query: 335 RPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSKL 394
             ++ E +R+  W TL+ G V+PG+GHAVLR+TDPRYT QREFALKHLP+D MF+LV++L
Sbjct: 325 E-VSDERMRDYIWNTLKSGRVVPGYGHAVLRKTDPRYTCQREFALKHLPNDPMFKLVAQL 383

Query: 395 YEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDR 454
           Y++VP VL EQGK KNPWPNVD HSG+LL+YYG+ E N+YTVLFGVSRALG L+ LVW R
Sbjct: 384 YKIVPNVLLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLVWSR 443

Query: 455 ALGLPIERPKSVTT 468
           ALG P+ERPKS++T
Sbjct: 444 ALGFPLERPKSMST 457


gb|AAH46571.1| Cs-prov protein [Xenopus laevis]
(468 aa)

Score: 531 bits (1369), Expect: 1.27637e-149
Length: 438, Idn/Pos/Gap = 248/323/5 (56%/73%/1%)

Query:  31 VRALSTSSATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYE  90
           + A   SS+T+L++ +   I   + ++   +++ G+ V+   TV+  YGGMR +K +VYE
Sbjct:  24 IAARQASSSTNLKDVLSDLIPKEQTRIKNFKQQHGKTVIGQVTVDMVYGGMRGMKGLVYE  83

Query:  91 TSLLDPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQD 150
           TS+LDP EGIRFRG+SIPECQ+LLP+A P GE+PLPEGL WLL+TGE+P + QV  + ++
Sbjct:  84 TSVLDPDEGIRFRGYSIPECQKLLPKA-PGGEEPLPEGLFWLLVTGEVPNQDQVNWISKE 142

Query: 151 LKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCL 210
             +RAA+P  V+ +LD  P   +HPM+Q S A++ L  ES  A AYA+G  K+ +WE   
Sbjct: 143 WAKRAALPSHVVTMLDNFP-TNLHPMSQLSAAITALNSESNFARAYAEGVNKAKYWELVY 201

Query: 211 EDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRL 270
           ED++ LIA+LP VAA+IYRN +  G  + A  I+   D        LG+   +F ELMRL
Sbjct: 202 EDSMDLIAKLPCVAAKIYRNLYREGSSIGA--IDSNLDWSDNFTNMLGYTDQQFTELMRL 259

Query: 271 YLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKE 330
           YL +H+DHEGGNVSAH   LVGSALSDPYLSF+A +NGLAGPLHGLANQEVL WL  +++
Sbjct: 260 YLTIHSDHEGGNVSAHTSHLVGSALSDPYLSFSAAMNGLAGPLHGLANQEVLVWLTSLQK 319

Query: 331 KLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQL 390
            LG   ++ E LR+  W TL  G V+PG+GHAVLR+TDPRYT QREFALKHLP D MF+L
Sbjct: 320 DLGGE-VSDEKLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYTCQREFALKHLPDDPMFKL 378

Query: 391 VSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSL 450
           V++LY++VP +L EQGK KNPWPNVD HSG+LL+YYG+ E N+YTVLFGVSRALG LS L
Sbjct: 379 VAQLYKIVPNILLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLSQL 438

Query: 451 VWDRALGLPIERPKSVTT 468
           +W RALG P+ERPKS++T
Sbjct: 439 IWSRALGFPLERPKSMST 456


gb|AAR98859.1| mitochondrial citrate synthase precursor [Thunnus obesus]
gb|AAR98858.1| mitochondrial citrate synthase precursor [Thunnus albacares]
(469 aa)

Score: 531 bits (1369), Expect: 1.33074e-149
Length: 435, Idn/Pos/Gap = 245/331/5 (56%/76%/1%)

Query:  35 STSSATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYETSLL  94
           +++S T+L++ +   I   ++++   ++++G+  +   TV+  YGGMR +K +VYETS+L
Sbjct:  29 ASASTTNLKDVLADLIPKEQSRIKNFKQQYGKTNIGQITVDMVYGGMRGMKGLVYETSVL  88

Query:  95 DPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRR 154
           DP+EGIRFRG+SIPECQ+LLP+A P GE+PLPEGL WLL+TG++PTE QV  V ++  +R
Sbjct:  89 DPEEGIRFRGYSIPECQKLLPKA-PGGEEPLPEGLFWLLVTGQVPTEEQVNWVSKEWAKR 147

Query: 155 AAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDAL 214
           AA+P  V+ +LD  P   +HPM+QFS A++ L  ES  A AY++G  K+ +WE+  ED++
Sbjct: 148 AALPSHVVTMLDNFP-TNLHPMSQFSAAITALNSESSFARAYSEGVHKTKYWEFVYEDSM 206

Query: 215 TLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVL 274
            LIA+LP +AA+IYRN +  G  + A  I+   D        LG+   +F ELMRLYL +
Sbjct: 207 DLIAKLPCIAAKIYRNLYREGSSIGA--IDSNLDWSHNFTNMLGYSEAQFTELMRLYLTI 264

Query: 275 HADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGN 334
           H+DHEGGNVSAH   LVGSALSDPYLSF+A +NGLAGPLHGLANQEVL WL  +++++G 
Sbjct: 265 HSDHEGGNVSAHTSHLVGSALSDPYLSFSAAMNGLAGPLHGLANQEVLVWLTALQKEMGG 324

Query: 335 RPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSKL 394
             ++ E +R+  W TL+ G V+PG+GHAVLR+TDPRYT QREFALKHLP+D MF+LV++L
Sbjct: 325 E-VSDERMRDYIWNTLKSGRVVPGYGHAVLRKTDPRYTCQREFALKHLPNDPMFKLVAQL 383

Query: 395 YEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDR 454
           Y++VP VL EQGK KNPWPNVD HSG+LL+YYG+ E N+YTVLFGVSRALG L+ LVW R
Sbjct: 384 YKIVPNVLLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLVWSR 443

Query: 455 ALGLPIERPKSVTTQ 469
           ALG P+ERPKS++T+
Sbjct: 444 ALGFPLERPKSMSTE 458


ref|NP_999441.1| citrate synthase [Sus scrofa]
sp|P00889|CISY_PIG Citrate synthase, mitochondrial precursor
gb|AAA31017.1| citrate synthase precursor (EC 4.1.3.7)
(464 aa)

Score: 531 bits (1368), Expect: 1.55935e-149
Length: 434, Idn/Pos/Gap = 250/327/5 (57%/75%/1%)

Query:  35 STSSATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYETSLL  94
           +++S+T+L++ +   I   +A++   R++ G  V+   TV+  YGGMR +K +VYETS+L
Sbjct:  26 ASASSTNLKDILADLIPKEQARIKTFRQQHGNTVVGQITVDMMYGGMRGMKGLVYETSVL  85

Query:  95 DPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRR 154
           DP EGIRFRG+SIPECQ++LP+AK  GE+PLPEGL WLL+TG+IPTE QV  + ++  +R
Sbjct:  86 DPDEGIRFRGYSIPECQKMLPKAK-GGEEPLPEGLFWLLVTGQIPTEEQVSWLSKEWAKR 144

Query: 155 AAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDAL 214
           AA+P  V+ +LD  P   +HPM+Q S A++ L  ES  A AYA+G  ++ +WE   ED +
Sbjct: 145 AALPSHVVTMLDNFP-TNLHPMSQLSAAITALNSESNFARAYAEGIHRTKYWELIYEDCM 203

Query: 215 TLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVL 274
            LIA+LP VAA+IYRN +  G  + A  I+   D        LG+   +F ELMRLYL +
Sbjct: 204 DLIAKLPCVAAKIYRNLYREGSSIGA--IDSKLDWSHNFTNMLGYTDAQFTELMRLYLTI 261

Query: 275 HADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGN 334
           H+DHEGGNVSAH   LVGSALSDPYLSFAA +NGLAGPLHGLANQEVL WL Q+++++G 
Sbjct: 262 HSDHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPLHGLANQEVLVWLTQLQKEVG- 320

Query: 335 RPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSKL 394
           + ++ E LR+  W TL  G V+PG+GHAVLR+TDPRYT QREFALKHLPHD MF+LV++L
Sbjct: 321 KDVSDEKLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYTCQREFALKHLPHDPMFKLVAQL 380

Query: 395 YEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDR 454
           Y++VP VL EQGK KNPWPNVD HSG+LL+YYG+ E N+YTVLFGVSRALG L+ L+W R
Sbjct: 381 YKIVPNVLLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLIWSR 440

Query: 455 ALGLPIERPKSVTT 468
           ALG P+ERPKS++T
Sbjct: 441 ALGFPLERPKSMST 454


pdb|4CTS|B Chain B, Citrate Synthase (E.C.4.1.3.7) - Oxaloacetate Complex
pdb|4CTS|A Chain A, Citrate Synthase (E.C.4.1.3.7) - Oxaloacetate Complex
pdb|1CTS| Citrate Synthase (E.C.4.1.3.7) - Citrate Complex
prf||0710290A:PDB=1CTS synthase,citrate
(437 aa)

Score: 531 bits (1368), Expect: 1.76725e-149
Length: 432, Idn/Pos/Gap = 250/325/5 (57%/75%/1%)

Query:  37 SSATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYETSLLDP  96
           +S+T+L++ +   I   +A++   R++ G  V+   TV+  YGGMR +K +VYETS+LDP
Sbjct:   1 ASSTNLKDILADLIPKEQARIKTFRQQHGNTVVGQITVDMMYGGMRGMKGLVYETSVLDP  60

Query:  97 QEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAA 156
            EGIRFRG+SIPECQ++LP+AK  GE+PLPEGL WLL+TG+IPTE QV  + ++  +RAA
Sbjct:  61 DEGIRFRGYSIPECQKMLPKAK-GGEEPLPEGLFWLLVTGQIPTEEQVSWLSKEWAKRAA 119

Query: 157 VPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTL 216
           +P  V+ +LD  P   +HPM+Q S A++ L  ES  A AYA+G  ++ +WE   ED + L
Sbjct: 120 LPSHVVTMLDNFP-TNLHPMSQLSAAITALNSESNFARAYAEGIHRTKYWELIYEDCMDL 178

Query: 217 IARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVLHA 276
           IA+LP VAA+IYRN +  G  + A  I+   D        LG+   +F ELMRLYL +H+
Sbjct: 179 IAKLPCVAAKIYRNLYREGSSIGA--IDSKLDWSHNFTNMLGYTDAQFTELMRLYLTIHS 236

Query: 277 DHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRP 336
           DHEGGNVSAH   LVGSALSDPYLSFAA +NGLAGPLHGLANQEVL WL Q+++++G + 
Sbjct: 237 DHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPLHGLANQEVLVWLTQLQKEVG-KD 295

Query: 337 MTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSKLYE 396
           ++ E LR+  W TL  G V+PG+GHAVLR+TDPRYT QREFALKHLPHD MF+LV++LY+
Sbjct: 296 VSDEKLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYTCQREFALKHLPHDPMFKLVAQLYK 355

Query: 397 VVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRAL 456
           +VP VL EQGK KNPWPNVD HSG+LL+YYG+ E N+YTVLFGVSRALG L+ L+W RAL
Sbjct: 356 IVPNVLLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLIWSRAL 415

Query: 457 GLPIERPKSVTT 468
           G P+ERPKS++T
Sbjct: 416 GFPLERPKSMST 427


gb|AAR98861.1| mitochondrial citrate synthase precursor [Xiphias gladius]
(469 aa)

Score: 530 bits (1366), Expect: 3.30423e-149
Length: 434, Idn/Pos/Gap = 246/329/5 (56%/75%/1%)

Query:  35 STSSATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYETSLL  94
           +++S+T+L++ +   I   + ++   ++++G+  +   TV+  YGGMR +K +VYETS+L
Sbjct:  29 ASASSTNLKDVLADLIPKEQTRIKNFKQQYGKTNIGQITVDMVYGGMRGMKGLVYETSVL  88

Query:  95 DPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRR 154
           DP+EGIRFRG+SIPECQ LLP+A P GE+PLPEGL WLL+TG++PTE QV  V ++  +R
Sbjct:  89 DPEEGIRFRGYSIPECQELLPKA-PGGEEPLPEGLFWLLVTGQVPTEEQVNWVSKEWAKR 147

Query: 155 AAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDAL 214
           AA+P  V+ +LD  P   +HPM+QFS A++ L  ES  A AY++G  K+ +WE+  ED++
Sbjct: 148 AALPSHVVTMLDNFP-TNLHPMSQFSAAITALNSESSFARAYSEGVHKTKYWEFIYEDSM 206

Query: 215 TLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVL 274
            LIA+LP +AA+IYRN +  G  + A  I+   D        LG+   +F ELMRLYL +
Sbjct: 207 DLIAKLPCIAAKIYRNLYREGSSIGA--IDSNLDWSHNFTNMLGYSEPQFTELMRLYLTI 264

Query: 275 HADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGN 334
           H+DHEGGNVSAH   LVGSALSDPYLSF+A +NGLAGPLHGLANQEVL WL  ++++LG 
Sbjct: 265 HSDHEGGNVSAHTSHLVGSALSDPYLSFSAAMNGLAGPLHGLANQEVLVWLTALQKELGG 324

Query: 335 RPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSKL 394
             ++ E +R+  W TL+ G V+PG+GHAVLR+TDPRYT QREFALKHLP+D MF+LV++L
Sbjct: 325 E-VSDERMRDYIWNTLKSGRVVPGYGHAVLRKTDPRYTCQREFALKHLPNDPMFKLVAQL 383

Query: 395 YEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDR 454
           Y++VP VL EQGK KNPWPNVD HSG+LL+YYG+ E N+YTVLFGVSRALG L+ LVW R
Sbjct: 384 YKIVPNVLLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLVWSR 443

Query: 455 ALGLPIERPKSVTT 468
           ALG P+ERPKS++T
Sbjct: 444 ALGFPLERPKSMST 457


gb|AAH45362.1| Citrate synthase [Danio rerio]
ref|NP_955892.1| citrate synthase [Danio rerio]
(468 aa)

Score: 530 bits (1365), Expect: 3.47386e-149
Length: 438, Idn/Pos/Gap = 247/331/5 (56%/75%/1%)

Query:  31 VRALSTSSATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYE  90
           V A + S++T+L++ +   +   ++++   ++++G+  +   TV+  YGGMR +K +VYE
Sbjct:  24 VAARNASASTNLKDVLSDLVPKEQSRIKNFKQQYGKTSIGQITVDMVYGGMRGVKGLVYE  83

Query:  91 TSLLDPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQD 150
           TS+LDP EGIRFRG+SIPECQ+LLP+A P GE+PLPEGL WLL+TG++PTE QV  + ++
Sbjct:  84 TSVLDPDEGIRFRGYSIPECQQLLPKA-PGGEEPLPEGLFWLLVTGQVPTEEQVSWLSKE 142

Query: 151 LKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCL 210
             +RAA+P  V+ +LD  P   +HPM+QFS A++ L  ES  A AY++G  K+ +WE+  
Sbjct: 143 WAKRAALPSHVVTMLDNFP-TNLHPMSQFSAAITALNSESSFARAYSEGVNKAKYWEFVY 201

Query: 211 EDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRL 270
           ED++ LIA+LP VAA+IYRN +  G  + A  I+   D        LG+   +F ELMRL
Sbjct: 202 EDSMDLIAKLPCVAAKIYRNLYREGSSIGA--IDSNLDWSHNFTNMLGYTEPQFTELMRL 259

Query: 271 YLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKE 330
           YL +H+DHEGGNVSAH   LVGSALSDPYLSF+A +NGLAGPLHGLANQEVL WL  +++
Sbjct: 260 YLTIHSDHEGGNVSAHTSHLVGSALSDPYLSFSAAMNGLAGPLHGLANQEVLVWLTALQK 319

Query: 331 KLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQL 390
           +LG   ++ E +R+  W TL+ G V+PG+GHAVLR+TDPRYT QREFALKHLP+D MF+L
Sbjct: 320 ELGGE-VSDEKMRDYIWNTLKSGRVVPGYGHAVLRKTDPRYTCQREFALKHLPNDPMFKL 378

Query: 391 VSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSL 450
           V++LY++VP VL EQGK KNPWPNVD HSG+LL+YYG+ E N+YTVLFGVSRALG L+ L
Sbjct: 379 VAQLYKIVPNVLLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQL 438

Query: 451 VWDRALGLPIERPKSVTT 468
           VW RALG P+ERPKS++T
Sbjct: 439 VWSRALGFPLERPKSMST 456


gb|AAR98862.1| mitochondrial citrate synthase precursor [Tetrapturus audax]
(469 aa)

Score: 530 bits (1365), Expect: 4.07063e-149
Length: 434, Idn/Pos/Gap = 245/330/5 (56%/76%/1%)

Query:  35 STSSATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYETSLL  94
           +++S+T+L++ +   I   + ++   ++++G+  +   TV+  YGGMR +K +VYETS+L
Sbjct:  29 ASASSTNLKDVLADLIPKEQTRIKNFKQQYGKTNIGQITVDMVYGGMRGMKGLVYETSVL  88

Query:  95 DPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRR 154
           DP+EGIRFRG+SIPECQ+LLP+A P GE+PLPEGL WLL+TG++PTE QV  V ++  +R
Sbjct:  89 DPEEGIRFRGYSIPECQKLLPKA-PGGEEPLPEGLFWLLVTGQVPTEEQVNWVSKEWAKR 147

Query: 155 AAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDAL 214
           AA+P  V+ +LD  P   +HPM+QFS A++ L  ES  A AY++G  KS +WE+  ED++
Sbjct: 148 AALPSHVVTMLDNFP-TNLHPMSQFSAAITALNSESSFARAYSEGVHKSKYWEFIYEDSM 206

Query: 215 TLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVL 274
            LIA+LP +AA+IYRN +  G  + A  I+   D        LG+   +F ELMRLYL +
Sbjct: 207 DLIAKLPCIAAKIYRNLYREGSSIGA--IDSNLDWSHNFTNMLGYSEPQFTELMRLYLTI 264

Query: 275 HADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGN 334
           H+DHEGGNVSAH   LVGSALSDPYLSF+A +NGLAGPLHGLANQEVL WL  ++++LG 
Sbjct: 265 HSDHEGGNVSAHTSHLVGSALSDPYLSFSAAMNGLAGPLHGLANQEVLVWLTALQKELGG 324

Query: 335 RPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSKL 394
             ++ E +R+  W TL+ G V+PG+GHAVLR+TDPRYT QREFALKHLP+D MF+LV++L
Sbjct: 325 E-VSDERMRDYIWNTLKSGRVVPGYGHAVLRKTDPRYTCQREFALKHLPNDPMFKLVAQL 383

Query: 395 YEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDR 454
           Y++VP VL EQG+ KNPWPNVD HSG+LL+YYG+ E N+YTVLFGVSRALG L+ LVW R
Sbjct: 384 YKIVPNVLLEQGRAKNPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLVWSR 443

Query: 455 ALGLPIERPKSVTT 468
           ALG P+ERPKS+++
Sbjct: 444 ALGFPLERPKSMSS 457


pdb|2CTS| Citrate Synthase (E.C.4.1.3.7) - (CoA, Citrate) Complex
(437 aa)

Score: 529 bits (1362), Expect: 9.1444e-149
Length: 432, Idn/Pos/Gap = 249/324/5 (57%/75%/1%)

Query:  37 SSATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYETSLLDP  96
           +S+T+L++ +   I   +A++   R++ G   +   TV+  YGGMR +K +VYETS+LDP
Sbjct:   1 ASSTNLKDILADLIPKEQARIKTFRQQHGNTAVGQITVDMMYGGMRGMKGLVYETSVLDP  60

Query:  97 QEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAA 156
            EGIRFRG+SIPECQ++LP+AK  GE+PLPEGL WLL+TG+IPTE QV  + ++  +RAA
Sbjct:  61 DEGIRFRGYSIPECQKMLPKAK-GGEEPLPEGLFWLLVTGQIPTEEQVSWLSKEWAKRAA 119

Query: 157 VPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTL 216
           +P  V+ +LD  P   +HPM+Q S A++ L  ES  A AYA+G  ++ +WE   ED + L
Sbjct: 120 LPSHVVTMLDNFP-TNLHPMSQLSAAITALNSESNFARAYAEGIHRTKYWELIYEDCMDL 178

Query: 217 IARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVLHA 276
           IA+LP VAA+IYRN +  G  + A  I+   D        LG+   +F ELMRLYL +H+
Sbjct: 179 IAKLPCVAAKIYRNLYREGSSIGA--IDSKLDWSHNFTNMLGYTDAQFTELMRLYLTIHS 236

Query: 277 DHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRP 336
           DHEGGNVSAH   LVGSALSDPYLSFAA +NGLAGPLHGLANQEVL WL Q+++++G + 
Sbjct: 237 DHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPLHGLANQEVLVWLTQLQKEVG-KD 295

Query: 337 MTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSKLYE 396
           ++ E LR+  W TL  G V+PG+GHAVLR+TDPRYT QREFALKHLPHD MF+LV++LY+
Sbjct: 296 VSDEKLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYTCQREFALKHLPHDPMFKLVAQLYK 355

Query: 397 VVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRAL 456
           +VP VL EQGK KNPWPNVD HSG+LL+YYG+ E N+YTVLFGVSRALG L+ L+W RAL
Sbjct: 356 IVPNVLLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLIWSRAL 415

Query: 457 GLPIERPKSVTT 468
           G P+ERPKS++T
Sbjct: 416 GFPLERPKSMST 427


ref|NP_082221.1| citrate synthase-like protein [Mus musculus]
dbj|BAB24200.1| unnamed protein product [Mus musculus]
(466 aa)

Score: 528 bits (1360), Expect: 1.35353e-148
Length: 434, Idn/Pos/Gap = 249/330/5 (57%/76%/1%)

Query:  35 STSSATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYETSLL  94
           +++S+T+L++ +R+ I   +A++   R++ G+ V+   TV+  YGGMR +K +VYETS+L
Sbjct:  26 ASASSTNLKDVLRNLIPKEQARIKTFRKKHGKTVVGQITVDMMYGGMRGMKGLVYETSVL  85

Query:  95 DPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRR 154
           DP EGIRFRG+SIPECQ+LLP+AK  G++PLPEGL WLL+TG++PTE QV  + Q+  +R
Sbjct:  86 DPDEGIRFRGYSIPECQKLLPKAK-GGKEPLPEGLFWLLVTGQMPTEEQVSWLSQEWVKR 144

Query: 155 AAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDAL 214
           AA+P  V+ +LD  P  ++HPM+Q S A+++L +ES  A AYAQG  ++ +WE   ED +
Sbjct: 145 AALPSHVVTMLDNFP-TKLHPMSQLSAAITVLNNESNFARAYAQGMNRTKYWELTYEDCM 203

Query: 215 TLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVL 274
            L+A+LP VAA+IYRN +   +++  E I+   D        LG+   +F ELMRLYL +
Sbjct: 204 DLLAKLPCVAAKIYRNLYREDRNI--EAIDSKLDWSHNFTNMLGYTDPQFTELMRLYLTI 261

Query: 275 HADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGN 334
           H+DHEGGNVSAH   LVGSALSDPYLSFAA LNGLAGPLHGLANQEVL WL Q+++++G 
Sbjct: 262 HSDHEGGNVSAHTSHLVGSALSDPYLSFAAALNGLAGPLHGLANQEVLVWLTQLQKEVG- 320

Query: 335 RPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSKL 394
              + E L+   W TL  G V+PG+GHAVLR+TDPRY+ QREFALKHLP D MF+LV +L
Sbjct: 321 EDASDEKLKNYIWNTLNSGRVVPGYGHAVLRKTDPRYSCQREFALKHLPKDPMFKLVGQL 380

Query: 395 YEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDR 454
           Y++VP +L EQGKVKNPWPNVD HSG+LL+YYG+ E N+YTVLFGVSRALG LS L+W R
Sbjct: 381 YKIVPDILLEQGKVKNPWPNVDAHSGVLLQYYGMREMNYYTVLFGVSRALGVLSQLIWSR 440

Query: 455 ALGLPIERPKSVTT 468
           ALG P+ERPKS++T
Sbjct: 441 ALGFPLERPKSMST 454


pdb|6CSC|B Chain B, Chicken Citrate Synthase Complex With Trifluoroacetonyl-Coa And Citrate
pdb|6CSC|A Chain A, Chicken Citrate Synthase Complex With Trifluoroacetonyl-Coa And Citrate
pdb|1AL6| Chicken Citrate Synthase Complex With N-Hydroxyamido-Coa And Oxaloacetate
(437 aa)

Score: 528 bits (1360), Expect: 1.66747e-148
Length: 432, Idn/Pos/Gap = 251/322/5 (58%/74%/1%)

Query:  37 SSATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYETSLLDP  96
           +S+T+L++ + S I   +A++   R++ G   +   TV+ +YGGMR +K ++YETS+LDP
Sbjct:   1 ASSTNLKDVLASLIPKEQARIKTFRQQHGNTAVGQITVDMSYGGMRGMKGLIYETSVLDP  60

Query:  97 QEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAA 156
            EGIRFRGFSIPECQ+LLP+A   GE+PLPEGL WLL+TG+IPT  QV  V ++  +RAA
Sbjct:  61 DEGIRFRGFSIPECQKLLPKAG-GGEEPLPEGLFWLLVTGQIPTPEQVSWVSKEWAKRAA 119

Query: 157 VPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTL 216
           +P  V+ +LD  P   +HPM+Q S A++ L  ES  A AYA+G  ++ +WE+  EDA+ L
Sbjct: 120 LPSHVVTMLDNFP-TNLHPMSQLSAAITALNSESNFARAYAEGINRTKYWEFVYEDAMDL 178

Query: 217 IARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVLHA 276
           IA+LP VAA+IYRN +  G  + A  I+   D        LG+   +F ELMRLYL +H+
Sbjct: 179 IAKLPCVAAKIYRNLYRAGSSIGA--IDSKLDWSHNFTNMLGYTDPQFTELMRLYLTIHS 236

Query: 277 DHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRP 336
           DHEGGNVSAH   LVGSALSDPYLSFAA +NGLAGPLHGLANQEVL WL Q+++ LG   
Sbjct: 237 DHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPLHGLANQEVLLWLSQLQKDLG-AD 295

Query: 337 MTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSKLYE 396
            + E LR+  W TL  G V+PG+GHAVLR+TDPRYT QREFALKHLP D MF+LV++LY+
Sbjct: 296 ASDEKLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYTCQREFALKHLPSDPMFKLVAQLYK 355

Query: 397 VVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRAL 456
           +VP VL EQGK KNPWPNVD HSG+LL+YYG+ E N+YTVLFGVSRALG L+ L+W RAL
Sbjct: 356 IVPNVLLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLIWSRAL 415

Query: 457 GLPIERPKSVTT 468
           G P+ERPKS++T
Sbjct: 416 GFPLERPKSMST 427


emb|CAG03961.1| unnamed protein product [Tetraodon nigroviridis]
(469 aa)

Score: 527 bits (1358), Expect: 2.23298e-148
Length: 434, Idn/Pos/Gap = 244/327/5 (56%/75%/1%)

Query:  35 STSSATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYETSLL  94
           +++S T+L++ +   I   + ++   ++++G+  +   TV+  YGGMR +K +VYETS+L
Sbjct:  29 ASASTTNLKDVLADLIPKEQNRIKNFKQQYGKTNIGQITVDMVYGGMRGMKGLVYETSVL  88

Query:  95 DPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRR 154
           DP EGIRFRG+SIPECQ+LLP+A   G++PLPEGL WLL+TG++PTE QV  V ++  +R
Sbjct:  89 DPDEGIRFRGYSIPECQKLLPKAA-GGQEPLPEGLFWLLVTGQVPTEEQVNWVSKEWAKR 147

Query: 155 AAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDAL 214
           AA+P  V+ +LD  P   +HPM+QFS AV+ L  ES  A AY++G  KS +WE+  ED++
Sbjct: 148 AALPSHVVTMLDNFP-TNLHPMSQFSAAVTALNSESSFARAYSEGVHKSKYWEFAYEDSM 206

Query: 215 TLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVL 274
            LIA+LP +AA+IYRN +  G  + A  I+   D        LG+   +F ELMRLYL +
Sbjct: 207 DLIAKLPCIAAKIYRNLYREGSSIGA--IDSGLDWSHNFTNMLGYSDAQFTELMRLYLTI 264

Query: 275 HADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGN 334
           H+DHEGGNVSAH   LVGSALSDPYL+F+A +NGLAGPLHGLANQEVL WL  ++++LG 
Sbjct: 265 HSDHEGGNVSAHTSHLVGSALSDPYLAFSAAMNGLAGPLHGLANQEVLVWLTALQKELGG 324

Query: 335 RPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSKL 394
             ++ E +R+  W TL+ G V+PG+GHAVLR+TDPRY+ QREFA+KHLP+D MF+LV++L
Sbjct: 325 E-VSDEKMRDYIWNTLKSGRVVPGYGHAVLRKTDPRYSCQREFAMKHLPNDPMFKLVAQL 383

Query: 395 YEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDR 454
           Y++VP VL EQGK KNPWPNVD HSG+LL+YYG+ E N+YTVLFGVSRALG LS LVW R
Sbjct: 384 YKIVPDVLLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLSQLVWSR 443

Query: 455 ALGLPIERPKSVTT 468
           ALG P+ERPKS++T
Sbjct: 444 ALGFPLERPKSMST 457


ref|NP_001017313.1| hypothetical protein LOC550067 [Xenopus tropicalis]
(468 aa)

Score: 527 bits (1358), Expect: 2.5519e-148
Length: 438, Idn/Pos/Gap = 247/323/5 (56%/73%/1%)

Query:  31 VRALSTSSATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYE  90
           + A   SS+ +L++ +   I   + ++   R+++G+ V+   TV+  YGGMR +K +VYE
Sbjct:  24 IAARQASSSANLKDVLSDLIPKEQTRIKNFRQQYGKNVIGQITVDMMYGGMRGMKGLVYE  83

Query:  91 TSLLDPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQD 150
           TS+LDP EGIRFRG+SIPECQ+LLP+A P GE+PLPEGL WLL+TGE P++ QV  + ++
Sbjct:  84 TSVLDPDEGIRFRGYSIPECQKLLPKA-PGGEEPLPEGLFWLLVTGEAPSQEQVNWISKE 142

Query: 151 LKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCL 210
             +RAA+P  V+ +LD  P   +HPM+Q S A++ L  ES  A  YA+G  K+ +WE   
Sbjct: 143 WAKRAALPSHVVTMLDNFP-TNLHPMSQLSAAITALNSESNFARGYAEGVNKTKYWELIY 201

Query: 211 EDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRL 270
           ED++ LIA+LP VAA+IYRN +  G  + A  I+   D        LG+   +F ELMRL
Sbjct: 202 EDSMDLIAKLPCVAAKIYRNLYREGSSIGA--IDSNLDWSHNFTNMLGYTDPQFTELMRL 259

Query: 271 YLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKE 330
           YL +H+DHEGGNVSAH   LVGSALSDPYLSF+A +NGLAGPLHGLANQEVL WL  +++
Sbjct: 260 YLTIHSDHEGGNVSAHTSHLVGSALSDPYLSFSAAMNGLAGPLHGLANQEVLVWLTSLQK 319

Query: 331 KLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQL 390
            LG   ++ E LR+  W TL  G V+PG+GHAVLR+TDPRYT QREFALKHLP+D MF+L
Sbjct: 320 DLGGE-VSDEKLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYTCQREFALKHLPNDPMFKL 378

Query: 391 VSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSL 450
           V++LY++VP VL EQGK KNPWPNVD HSG+LL+YYG+ E N+YTVLFGVSRALG L+ L
Sbjct: 379 VAQLYKIVPNVLLEQGKAKNPWPNVDAHSGVLLQYYGMKEMNYYTVLFGVSRALGVLAQL 438

Query: 451 VWDRALGLPIERPKSVTT 468
           +W RALG P+ERPKS++T
Sbjct: 439 IWSRALGFPLERPKSMST 456


gb|AAH50750.1| Citrate synthase-like protein [Mus musculus]
(466 aa)

Score: 526 bits (1355), Expect: 4.89224e-148
Length: 434, Idn/Pos/Gap = 248/329/5 (57%/75%/1%)

Query:  35 STSSATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYETSLL  94
           +++S+T+L++ +R+ I   +A++   R++ G+ V+   TV+  YGGMR +K +VYETS+L
Sbjct:  26 ASASSTNLKDVLRNLIPKEQARIKTFRKKHGKTVVGQITVDMMYGGMRGMKGLVYETSVL  85

Query:  95 DPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRR 154
           DP EGIRFRG+SIPECQ+LLP+AK  G++PLPEGL WLL+TG++PTE QV  + Q+  +R
Sbjct:  86 DPDEGIRFRGYSIPECQKLLPKAK-GGKEPLPEGLFWLLVTGQMPTEEQVSWLSQEWVKR 144

Query: 155 AAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDAL 214
           AA+P  V+ +LD  P  ++HPM+Q S A+++L +ES  A AYAQG  ++ +WE   ED +
Sbjct: 145 AALPSHVVTMLDNFP-TKLHPMSQLSAAITVLNNESNFARAYAQGMNRTKYWELTYEDCM 203

Query: 215 TLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVL 274
            L+A+LP VAA+IYRN +   +++  E I+   D        LG+   +F ELMRLYL +
Sbjct: 204 DLLAKLPCVAAKIYRNLYREDRNI--EAIDSKLDWSHNFTNMLGYTDPQFTELMRLYLTI 261

Query: 275 HADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGN 334
           H+DHEGGNVSAH   LVGSALSDPYLSFAA LNGLAGPLHGLANQEVL WL Q+++++G 
Sbjct: 262 HSDHEGGNVSAHTSHLVGSALSDPYLSFAAALNGLAGPLHGLANQEVLVWLTQLQKEVG- 320

Query: 335 RPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSKL 394
              + E L+   W TL  G V+PG+GHAVLR+TDPRY+ QREFALKHLP D MF+LV +L
Sbjct: 321 EDASDEKLKNYIWNTLNSGRVVPGYGHAVLRKTDPRYSCQREFALKHLPKDPMFKLVGQL 380

Query: 395 YEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDR 454
           Y++VP +L EQGK KNPWPNVD HSG+LL+YYG+ E N+YTVLFGVSRALG LS L+W R
Sbjct: 381 YKIVPDILLEQGKAKNPWPNVDAHSGVLLQYYGMREMNYYTVLFGVSRALGVLSQLIWSR 440

Query: 455 ALGLPIERPKSVTT 468
           ALG P+ERPKS++T
Sbjct: 441 ALGFPLERPKSMST 454


pdb|1AMZ| Chicken Citrate Synthase Complex With Nitromethylde-Coa And Malate
pdb|1CSS| Mol_id: 1; Molecule: Citrate Synthase; Chain: Null; Ec: 4.1.3.7; Heterogen: Oxaloacetate; Heterogen: Alpha-Fluoro-Carboxymethyldethia Coenzyme A
pdb|1CSR| Mol_id: 1; Molecule: Citrate Synthase; Chain: Null; Ec: 4.1.3.7; Heterogen: Oxaloacetate; Heterogen: Alpha-Fluoro-Amidocarboxymethyldethia Coenzyme A
pdb|1CSI| Citrate Synthase (E.C.4.1.3.7) Complexed With Oxaloacetate And Carboxymethyldethia Coenzyme A
pdb|1CSH| Citrate Synthase (E.C.4.1.3.7) Complexed With Oxaloacetate And Amidocarboxymethyldethia Coenzyme A
(435 aa)

Score: 526 bits (1354), Expect: 6.88775e-148
Length: 430, Idn/Pos/Gap = 250/320/5 (58%/74%/1%)

Query:  39 ATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYETSLLDPQE  98
           +T+L++ + S I   +A++   R++ G   +   TV+ +YGGMR +K ++YETS+LDP E
Sbjct:   1 STNLKDVLASLIPKEQARIKTFRQQHGNTAVGQITVDMSYGGMRGMKGLIYETSVLDPDE  60

Query:  99 GIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVP 158
           GIRFRGFSIPECQ+LLP+A   GE+PLPEGL WLL+TG+IPT  QV  V ++  +RAA+P
Sbjct:  61 GIRFRGFSIPECQKLLPKAG-GGEEPLPEGLFWLLVTGQIPTPEQVSWVSKEWAKRAALP 119

Query: 159 PEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIA 218
             V+ +LD  P   +HPM+Q S A++ L  ES  A AYA+G  ++ +WE+  EDA+ LIA
Sbjct: 120 SHVVTMLDNFP-TNLHPMSQLSAAITALNSESNFARAYAEGINRTKYWEFVYEDAMDLIA 178

Query: 219 RLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVLHADH 278
           +LP VAA+IYRN +  G  + A  I+   D        LG+   +F ELMRLYL +H+DH
Sbjct: 179 KLPCVAAKIYRNLYRAGSSIGA--IDSKLDWSHNFTNMLGYTDPQFTELMRLYLTIHSDH 236

Query: 279 EGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMT 338
           EGGNVSAH   LVGSALSDPYLSFAA +NGLAGPLHGLANQEVL WL Q+++ LG    +
Sbjct: 237 EGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPLHGLANQEVLLWLSQLQKDLG-ADAS 295

Query: 339 TENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSKLYEVV 398
            E LR+  W TL  G V+PG+GHAVLR+TDPRYT QREFALKHLP D MF+LV++LY++V
Sbjct: 296 DEKLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYTCQREFALKHLPSDPMFKLVAQLYKIV 355

Query: 399 PRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGL 458
           P VL EQGK KNPWPNVD HSG+LL+YYG+ E N+YTVLFGVSRALG L+ L+W RALG 
Sbjct: 356 PNVLLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLIWSRALGF 415

Query: 459 PIERPKSVTT 468
           P+ERPKS++T
Sbjct: 416 PLERPKSMST 425


ref|NP_570111.1| citrate synthase [Rattus norvegicus]
gb|AAL66372.1| citrate synthase [Rattus norvegicus]
(466 aa)

Score: 524 bits (1350), Expect: 2.29025e-147
Length: 445, Idn/Pos/Gap = 247/331/5 (55%/74%/1%)

Query:  35 STSSATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYETSLL  94
           +++S+T+L++ + + I   +A+V   R++ G+ V+   TV+  YGGMR +K +VYETS+L
Sbjct:  26 ASASSTNLKDILSNLIPKEQARVKTFRQQHGKTVVGQITVDMMYGGMRGMKGLVYETSVL  85

Query:  95 DPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRR 154
           DP EGIRFRG+SIPECQ+LLP+AK  GE+PLPEGL WLL+TG++PTE QV  + Q+  +R
Sbjct:  86 DPDEGIRFRGYSIPECQKLLPKAK-GGEEPLPEGLFWLLVTGQMPTEEQVSWLSQEWAKR 144

Query: 155 AAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDAL 214
           AA+P  V+ +LD  P   +HPM+Q S A++ L  ES  A AYA+G  ++ +WE   ED +
Sbjct: 145 AALPSHVVTMLDNFP-TNLHPMSQLSAAITALNSESNFARAYAEGINRTKYWELIYEDCM 203

Query: 215 TLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVL 274
            LIA+LP VAA+IYRN +  G  + A  I+   D        L +   +F ELMRLYL +
Sbjct: 204 DLIAKLPCVAAKIYRNLYREGSSIGA--IDSKLDWSHNFTNMLCYTEPQFTELMRLYLTI 261

Query: 275 HADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGN 334
           H+DH+GGNVSAH   LVGSALSD YLSFAA +NGLAGPLHGLANQEVL WL Q+++++G 
Sbjct: 262 HSDHDGGNVSAHTSHLVGSALSDTYLSFAAAMNGLAGPLHGLANQEVLVWLTQLQKEVG- 320

Query: 335 RPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSKL 394
           + ++ E LR+  W TL  G V+PG+GHAVLR+TDPRY+ QREFALKHLP D MF+LV++L
Sbjct: 321 KDVSDEKLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYSCQREFALKHLPKDPMFKLVAQL 380

Query: 395 YEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDR 454
           Y++VP +L EQGK KNPWPNVD HSG+LL+YYG+ E N+YTVLFGVSRALG L+ L+W R
Sbjct: 381 YKIVPNILLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLIWSR 440

Query: 455 ALGLPIERPKSVTTQWIREHFEKRS 479
           ALG P+ERPKS++T  + +  + +S
Sbjct: 441 ALGFPLERPKSMSTDGLMKFVDSKS 465


ref|NP_080720.1| citrate synthase [Mus musculus]
gb|AAH13554.1| Citrate synthase [Mus musculus]
gb|AAH29754.1| Citrate synthase [Mus musculus]
dbj|BAB63945.1| citrate synthase [Mus musculus]
sp|Q9CZU6|CYSY_MOUSE Citrate synthase, mitochondrial precursor
dbj|BAB28063.1| unnamed protein product [Mus musculus]
(464 aa)

Score: 524 bits (1349), Expect: 2.59559e-147
Length: 434, Idn/Pos/Gap = 245/328/5 (56%/75%/1%)

Query:  35 STSSATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYETSLL  94
           +++S+T+L++ + + I   +A++   +++ G+ V+   TV+  YGGMR +K +VYETS+L
Sbjct:  26 ASASSTNLKDVLSNLIPKEQARIKTFKQQHGKTVVGQITVDMMYGGMRGMKGLVYETSVL  85

Query:  95 DPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRR 154
           DP EGIRFRG+SIPECQ++LP+AK  GE+PLPEGL WLL+TG++PTE QV  + ++  +R
Sbjct:  86 DPDEGIRFRGYSIPECQKMLPKAK-GGEEPLPEGLFWLLVTGQMPTEEQVSWLSREWAKR 144

Query: 155 AAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDAL 214
           AA+P  V+ +LD  P   +HPM+Q S A++ L  ES  A AYA+G  ++ +WE   ED +
Sbjct: 145 AALPSHVVTMLDNFP-TNLHPMSQLSAAITALNSESNFARAYAEGMNRAKYWELIYEDCM 203

Query: 215 TLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVL 274
            LIA+LP VAA+IYRN +  G  + A  I+   D        LG+   +F ELMRLYL +
Sbjct: 204 DLIAKLPCVAAKIYRNLYREGSSIGA--IDSRLDWSHNFTNMLGYTDPQFTELMRLYLTI 261

Query: 275 HADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGN 334
           H+DHEGGNVSAH   LVGSALSDPYLSFAA +NGLAGPLHGLANQEVL WL Q+++++G 
Sbjct: 262 HSDHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPLHGLANQEVLVWLTQLQKEVG- 320

Query: 335 RPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSKL 394
           + ++ E LR+  W TL  G V+PG+GHAVLR+TDPRY+ QREFALKHLP D MF+LV++L
Sbjct: 321 KDVSDEKLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYSCQREFALKHLPKDPMFKLVAQL 380

Query: 395 YEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDR 454
           Y++VP +L EQGK KNPWPNVD HSG+LL+YYG+ E N+YTVLFGVSRALG L+ L+W R
Sbjct: 381 YKIVPNILLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLIWSR 440

Query: 455 ALGLPIERPKSVTT 468
           ALG P+ERPKS++T
Sbjct: 441 ALGFPLERPKSMST 454


gb|AAH00105.3| CS protein [Homo sapiens]
(409 aa)

Score: 520 bits (1340), Expect: 3.17198e-146
Length: 412, Idn/Pos/Gap = 246/313/5 (59%/75%/1%)

Query:  68 VLDACTVNQAYGGMRSLKAMVYETSLLDPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPE 127
           V+   TV+  YGGMR +K +VYETS+LDP EGIRFRGFSIPECQ+LLP+AK  GE+PLPE
Sbjct:   2 VVGQITVDMMYGGMRGMKGLVYETSVLDPDEGIRFRGFSIPECQKLLPKAK-GGEEPLPE  60

Query: 128 GLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQ 187
           GL WLL+TG IPTE QV  + ++  +RAA+P  V+ +LD  P   +HPM+Q S AV+ L 
Sbjct:  61 GLFWLLVTGHIPTEEQVSWLSKEWAKRAALPSHVVTMLDNFP-TNLHPMSQLSAAVTALN 119

Query: 188 HESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVD 247
            ES  A AYAQG  ++ +WE   ED++ LIA+LP VAA+IYRN +  G  + A  I+   
Sbjct: 120 SESNFARAYAQGISRTKYWELIYEDSMDLIAKLPCVAAKIYRNLYREGSGIGA--IDSNL 177

Query: 248 DMGMRLARSLGFELNEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLN 307
           D        LG+  ++F EL RLYL +H+DHEGGNVSAH   LVGSALSDPYLSFAA +N
Sbjct: 178 DWSHNFTNMLGYTDHQFTELTRLYLTIHSDHEGGNVSAHTSHLVGSALSDPYLSFAAAMN 237

Query: 308 GLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRT 367
           GLAGPLHGLANQEVL WL Q+++++G + ++ E LR+  W TL  G V+PG+GHAVLR+T
Sbjct: 238 GLAGPLHGLANQEVLVWLTQLQKEVG-KDVSDEKLRDYIWNTLNSGRVVPGYGHAVLRKT 296

Query: 368 DPRYTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYG 427
           DPRYT QREFALKHLP+D MF+LV++LY++VP VL EQGK KNPWPNVD HSG+LL+YYG
Sbjct: 297 DPRYTCQREFALKHLPNDPMFKLVAQLYKIVPNVLLEQGKAKNPWPNVDAHSGVLLQYYG 356

Query: 428 LVESNFYTVLFGVSRALGTLSSLVWDRALGLPIERPKSVTTQWIREHFEKRS 479
           + E N+YTVLFGVSRALG L+ L+W RALG P+ERPKS++T+ + +  + +S
Sbjct: 357 MTEMNYYTVLFGVSRALGVLAQLIWSRALGFPLERPKSMSTEGLMKFVDSKS 408


ref|XP_582992.1| PREDICTED: similar to citrate (si)-synthase (EC 4.1.3.7) precursor - pig [Bos taurus]
(603 aa)

Score: 518 bits (1333), Expect: 2.19794e-145
Length: 445, Idn/Pos/Gap = 251/332/5 (56%/74%/1%)

Query:  35 STSSATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYETSLL  94
           +++S+T+L++ +   I   + +V   R++ G+ V+   TV+  YGGMR +K +VYETS+L
Sbjct: 163 ASASSTNLKDILADLIPKEQTRVKAFRQQHGKTVVGQITVDMMYGGMRGMKGLVYETSVL 222

Query:  95 DPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRR 154
           DP EGIRFRG+SIPECQ+LLP+AK  GE+PLPEGL WLL+TG+IPTE QV  + Q+  +R
Sbjct: 223 DPDEGIRFRGYSIPECQKLLPKAK-GGEEPLPEGLFWLLVTGQIPTEEQVSWLSQEWAKR 281

Query: 155 AAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDAL 214
           AA+P  V+ +LD  P   +HPM+Q S AV+ L  ES  A AY++G  ++ +WE   ED++
Sbjct: 282 AALPSHVVTMLDNFP-TNLHPMSQLSAAVTALNSESTFARAYSEGINRTKYWELIYEDSM 340

Query: 215 TLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVL 274
            LIA+LP VAA+IYRN +  G  + A  I+   D        LG+   +F ELMRLYL +
Sbjct: 341 DLIAKLPCVAAKIYRNLYREGSSIGA--IDPKLDWSHNFTNMLGYTDAQFTELMRLYLTI 398

Query: 275 HADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGN 334
           H+DHEGGNVSAH   LVGSALSDPYLSFAA +NGLAGPLHGLANQEVL WL Q+++++G 
Sbjct: 399 HSDHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPLHGLANQEVLVWLTQLQKEVG- 457

Query: 335 RPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSKL 394
           + ++ E LR+  W TL  G V+PG+GHAVLR+TDPRYT QREFALKHLP D MF+LV++L
Sbjct: 458 KDVSDEKLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYTCQREFALKHLPQDPMFKLVAQL 517

Query: 395 YEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDR 454
           Y++VP +L EQGK KNPWPNVD HSG+LL+YYG+ E N+YTVLFGVSRALG L+ L+W R
Sbjct: 518 YKIVPNILLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLIWSR 577

Query: 455 ALGLPIERPKSVTTQWIREHFEKRS 479
           ALG P+ERPKS++T  + +  + +S
Sbjct: 578 ALGFPLERPKSMSTDGLMKFVDSKS 602


emb|CAB77625.1| citrate synthase [Aspergillus niger]
(474 aa)

Score: 515 bits (1326), Expect: 1.25706e-144
Length: 441, Idn/Pos/Gap = 252/321/7 (57%/72%/1%)

Query:  30 AVRALSTSSATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVY  89
            +R  ST  A SL+E    K+     +V ++R+  G +V+   T++QAYGG R +K +V+
Sbjct:  30 GLRCYSTGKAKSLKETFAEKLPAEIEKVKKLRKEHGSKVIGEVTLDQAYGGARGVKCLVW  89

Query:  90 ETSLLDPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQ 149
           E S+LD +EGIRFRG +IPECQ LLP+A P G++PLPEGL WLLLTGEIPTE QV  +  
Sbjct:  90 EGSVLDSEEGIRFRGRTIPECQELLPKA-PGGQEPLPEGLFWLLLTGEIPTEQQVRDLSA 148

Query: 150 DLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYC 209
           +   R+ +P  +  L+D  P   +HPM+QFS+AV+ L+HES  A+AYA+G  K  +W Y 
Sbjct: 149 EWAARSDLPKFIEELIDRCP-STLHPMSQFSLAVTALEHESAFAKAYAKGINKKDYWNYT 207

Query: 210 LEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGF-ELNEFDELM 268
            ED++ LIA+LP +AA+IYRN F  GK  P   I+K  D    LA  LG+ + N+F ELM
Sbjct: 208 FEDSMDLIAKLPTIAAKIYRNVFKDGKVAP---IQKDKDYSYNLANQLGYGDNNDFVELM 264

Query: 269 RLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQM 328
           RLYL +H+DHEGGNVSAH   LVGSALS P LS AAGLNGLAGPLHGLANQEVL WL +M
Sbjct: 265 RLYLTIHSDHEGGNVSAHTTHLVGSALSSPMLSLAAGLNGLAGPLHGLANQEVLNWLTKM 324

Query: 329 KEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMF 388
           K  +GN  ++ E ++   W TL  G V+PG+GHAVLR+TDPRY +QREFAL+ LP D MF
Sbjct: 325 KAAIGN-DLSDEAIKNYLWSTLNAGQVVPGYGHAVLRKTDPRYVSQREFALRKLPDDPMF 383

Query: 389 QLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLS 448
           +LVS++Y++ P VL E GK KNP+PNVD HSG+LL+YYGL E+N+YTVLFGVSRALG L 
Sbjct: 384 KLVSQVYKIAPGVLTEHGKTKNPYPNVDAHSGVLLQYYGLTEANYYTVLFGVSRALGVLP 443

Query: 449 SLVWDRALGLPIERPKSVTTQ 469
            L+ DRALG PIERPKS +T+
Sbjct: 444 QLIIDRALGAPIERPKSYSTE 464


dbj|BAA09691.1| citrate synthase precursor [Aspergillus niger]
sp|P51044|CISY_ASPNG Citrate synthase, mitochondrial precursor
(475 aa)

Score: 514 bits (1325), Expect: 1.56161e-144
Length: 441, Idn/Pos/Gap = 252/321/7 (57%/72%/1%)

Query:  30 AVRALSTSSATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVY  89
            +R  ST  A SL+E    K+     +V ++R+  G +V+   T++QAYGG R +K +V+
Sbjct:  30 GLRCYSTGKAKSLKETFAEKLPAELEKVKKLRKEHGSKVIGEVTLDQAYGGARGVKCLVW  89

Query:  90 ETSLLDPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQ 149
           E S+LD +EGIRFRG +IPECQ LLP+A P G++PLPEGL WLLLTGEIPTE QV  +  
Sbjct:  90 EGSVLDSEEGIRFRGRTIPECQELLPKA-PGGQEPLPEGLFWLLLTGEIPTEQQVRDLSA 148

Query: 150 DLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYC 209
           +   R+ +P  +  L+D  P   +HPM+QFS+AV+ L+HES  A+AYA+G  K  +W Y 
Sbjct: 149 EWAARSDLPKFIEELIDRCP-STLHPMSQFSLAVTALEHESAFAKAYAKGINKKDYWNYT 207

Query: 210 LEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGF-ELNEFDELM 268
            ED++ LIA+LP +AA+IYRN F  GK  P   I+K  D    LA  LG+ + N+F ELM
Sbjct: 208 FEDSMDLIAKLPTIAAKIYRNVFKDGKVAP---IQKDKDYSYNLANQLGYGDNNDFVELM 264

Query: 269 RLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQM 328
           RLYL +H+DHEGGNVSAH   LVGSALS P LS AAGLNGLAGPLHGLANQEVL WL +M
Sbjct: 265 RLYLTIHSDHEGGNVSAHTTHLVGSALSSPMLSLAAGLNGLAGPLHGLANQEVLNWLTKM 324

Query: 329 KEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMF 388
           K  +GN  ++ E ++   W TL  G V+PG+GHAVLR+TDPRY +QREFAL+ LP D MF
Sbjct: 325 KAAIGN-DLSDEAIKNYLWSTLNAGQVVPGYGHAVLRKTDPRYVSQREFALRKLPDDPMF 383

Query: 389 QLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLS 448
           +LVS++Y++ P VL E GK KNP+PNVD HSG+LL+YYGL E+N+YTVLFGVSRALG L 
Sbjct: 384 KLVSQVYKIAPGVLTEHGKTKNPYPNVDAHSGVLLQYYGLTEANYYTVLFGVSRALGVLP 443

Query: 449 SLVWDRALGLPIERPKSVTTQ 469
            L+ DRALG PIERPKS +T+
Sbjct: 444 QLIIDRALGAPIERPKSYSTE 464


emb|CAE45911.1| hypothetical protein [Homo sapiens]
ref|NP_938083.1| citrate synthase precursor, isoform b [Homo sapiens]
(400 aa)

Score: 514 bits (1325), Expect: 1.61461e-144
Length: 402, Idn/Pos/Gap = 243/308/5 (60%/76%/1%)

Query:  78 YGGMRSLKAMVYETSLLDPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGE 137
           YGGMR +K +VYETS+LDP EGIRFRGFSIPECQ+LLP+AK  GE+PLPEGL WLL+TG 
Sbjct:   3 YGGMRGMKGLVYETSVLDPDEGIRFRGFSIPECQKLLPKAK-GGEEPLPEGLFWLLVTGH  61

Query: 138 IPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYA 197
           IPTE QV  + ++  +RAA+P  V+ +LD  P   +HPM+Q S AV+ L  ES  A AYA
Sbjct:  62 IPTEEQVSWLSKEWAKRAALPSHVVTMLDNFP-TNLHPMSQLSAAVTALNSESNFARAYA 120

Query: 198 QGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSL 257
           QG  ++ +WE   ED++ LIA+LP VAA+IYRN +  G  + A  I+   D        L
Sbjct: 121 QGISRTKYWELIYEDSMDLIAKLPCVAAKIYRNLYREGSGIGA--IDSNLDWSHNFTNML 178

Query: 258 GFELNEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLA 317
           G+  ++F EL RLYL +H+DHEGGNVSAH   LVGSALSDPYLSFAA +NGLAGPLHGLA
Sbjct: 179 GYTDHQFTELTRLYLTIHSDHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPLHGLA 238

Query: 318 NQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREF 377
           NQEVL WL Q+++++G + ++ E LR+  W TL  G V+PG+GHAVLR+TDPRYT QREF
Sbjct: 239 NQEVLVWLTQLQKEVG-KDVSDEKLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYTCQREF 297

Query: 378 ALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVL 437
           ALKHLP+D MF+LV++LY++VP VL EQGK KNPWPNVD HSG+LL+YYG+ E N+YTVL
Sbjct: 298 ALKHLPNDPMFKLVAQLYKIVPNVLLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYYTVL 357

Query: 438 FGVSRALGTLSSLVWDRALGLPIERPKSVTTQWIREHFEKRS 479
           FGVSRALG L+ L+W RALG P+ERPKS++T+ + +  + +S
Sbjct: 358 FGVSRALGVLAQLIWSRALGFPLERPKSMSTEGLMKFVDSKS 399


gb|EAA59013.1| CISY_EMENI Citrate synthase, mitochondrial precursor [Aspergillus nidulans FGSC A4]
ref|XP_412412.1| CISY_EMENI Citrate synthase, mitochondrial precursor [Aspergillus nidulans FGSC A4]
(474 aa)

Score: 514 bits (1324), Expect: 2.10874e-144
Length: 441, Idn/Pos/Gap = 250/322/7 (56%/73%/1%)

Query:  30 AVRALSTSSATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVY  89
            +R  ST    SL+E    K+     +V ++R+  G +V+   T++QAYGG R +K +V+
Sbjct:  30 GLRCYSTGKTKSLKETFADKLPGELEKVKKLRKEHGNKVIGELTLDQAYGGARGVKCLVW  89

Query:  90 ETSLLDPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQ 149
           E S+LD +EGIRFRG +IPECQ+LLP+A P GE+PLPEGL WLLLTGE+P+E QV  +  
Sbjct:  90 EGSVLDSEEGIRFRGLTIPECQKLLPKA-PGGEEPLPEGLFWLLLTGEVPSEQQVRDLSA 148

Query: 150 DLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYC 209
           +   R+ +P  +  L+D  P   +HPM QFS+AV+ L+HES  A+AYA+G  K  +W Y 
Sbjct: 149 EWAARSDLPKFIEELIDRCP-STLHPMAQFSLAVTALEHESAFAKAYAKGINKKEYWHYT 207

Query: 210 LEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELN-EFDELM 268
            ED++ LIA+LP +AA+IYRN F  GK  P   I+K  D    LA  LGF  N +F ELM
Sbjct: 208 FEDSMDLIAKLPTIAAKIYRNVFKDGKVAP---IQKDKDYSYNLANQLGFADNKDFVELM 264

Query: 269 RLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQM 328
           RLYL +H+DHEGGNVSAH   LVGSALS P LS AAGLNGLAGPLHGLANQEVL WL +M
Sbjct: 265 RLYLTIHSDHEGGNVSAHTTHLVGSALSSPMLSLAAGLNGLAGPLHGLANQEVLNWLTEM 324

Query: 329 KEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMF 388
           K+ +GN  ++ +++++  W TL  G V+PG+GHAVLR+TDPRYT+QREFAL+ LP D MF
Sbjct: 325 KKVVGN-DLSDQSIKDYLWSTLNAGRVVPGYGHAVLRKTDPRYTSQREFALRKLPDDPMF 383

Query: 389 QLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLS 448
           +LVS++Y++ P VL E GK KNP+PNVD HSG+LL+YYGL E+N+YTVLFGVSRALG L 
Sbjct: 384 KLVSQVYKIAPGVLTEHGKTKNPYPNVDAHSGVLLQYYGLTEANYYTVLFGVSRALGVLP 443

Query: 449 SLVWDRALGLPIERPKSVTTQ 469
            L+ DRA G PIERPKS +T+
Sbjct: 444 QLIIDRAFGAPIERPKSFSTE 464


gb|AAC49728.3| citrate synthase [Aspergillus nidulans]
gb|AAM22645.1| citrate synthase [Emericella nidulans]
sp|O00098|CISY_EMENI Citrate synthase, mitochondrial precursor
(474 aa)

Score: 511 bits (1317), Expect: 1.32198e-143
Length: 441, Idn/Pos/Gap = 249/322/7 (56%/73%/1%)

Query:  30 AVRALSTSSATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVY  89
            +R  ST    SL+E    K+     +V ++R+  G +V+   T++QAYGG R +K +V+
Sbjct:  30 GLRCYSTGKTKSLKETFADKLPGELEKVKKLRKEHGNKVIGELTLDQAYGGARGVKCLVW  89

Query:  90 ETSLLDPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQ 149
           E S+LD +EGIRFRG +IPECQ+LLP+A P GE+PLPEGL WLLLTGE+P+E QV  +  
Sbjct:  90 EGSVLDSEEGIRFRGLTIPECQKLLPKA-PGGEEPLPEGLFWLLLTGEVPSEQQVRDLSA 148

Query: 150 DLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYC 209
           +   R+ +P  +  L+D +P   +HPM QFS+AV+ L+HES  A+A A+G  K  +W Y 
Sbjct: 149 EWAARSDLPKFIEELIDRVP-STLHPMAQFSLAVTALEHESAFAKATAKGINKKEYWHYT 207

Query: 210 LEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELN-EFDELM 268
            ED++ LIA+LP +AA+IYRN F  GK  P   I+K  D    LA  LGF  N +F ELM
Sbjct: 208 FEDSMDLIAKLPTIAAKIYRNVFKDGKVAP---IQKDKDYSYNLANQLGFADNKDFVELM 264

Query: 269 RLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQM 328
           RLYL +H+DHEGGNVSAH   LVGSALS P LS AAGLNGLAGPLHGLANQEVL WL +M
Sbjct: 265 RLYLTIHSDHEGGNVSAHTTHLVGSALSSPMLSLAAGLNGLAGPLHGLANQEVLNWLTEM 324

Query: 329 KEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMF 388
           K+ +GN  ++ +++++  W TL  G V+PG+GHAVLR+TDPRYT+QREFAL+ LP D MF
Sbjct: 325 KKVVGN-DLSDQSIKDYLWSTLNAGRVVPGYGHAVLRKTDPRYTSQREFALRKLPDDPMF 383

Query: 389 QLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLS 448
           +LVS++Y++ P VL E GK KNP+PNVD HSG+LL+YYGL E+N+YTVLFGVSRALG L 
Sbjct: 384 KLVSQVYKIAPGVLTEHGKTKNPYPNVDAHSGVLLQYYGLTEANYYTVLFGVSRALGVLP 443

Query: 449 SLVWDRALGLPIERPKSVTTQ 469
            L+ DRA G PIERPKS +T+
Sbjct: 444 QLIIDRAFGAPIERPKSFSTE 464


sp|P23007|CISY_CHICK Citrate synthase, mitochondrial
pdb|6CTS| Citrate Synthase (E.C.4.1.3.7) - Citrylthioether - Coenzyme A Complex
pdb|5CTS| Citrate Synthase (E.C.4.1.3.7)- Oxaloacetate - Carboxymethyl Coenzyme A Complex
pdb|4CSC| Citrate Synthase (E.C.4.1.3.7)- D-Malate - Acetyl Coenzyme A Complex
pdb|3CSC| Citrate Synthase (E.C.4.1.3.7)- L-Malate - Acetyl Coenzyme A Complex
pdb|2CSC| Citrate Synthase (E.C.4.1.3.7)- D-Malate - Carboxymethyl Coenzyme A Complex
pdb|1CSC| Citrate Synthase (E.C.4.1.3.7)- L-Malate - Carboxymethyl Coenzyme A Complex
(433 aa)

Score: 510 bits (1313), Expect: 4.39572e-143
Length: 432, Idn/Pos/Gap = 245/314/5 (56%/72%/1%)

Query:  37 SSATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYETSLLDP  96
           +S+T+L++ + + I   +A++   R++ G   L   TV+ +YGGMR +K +VYETS+LDP
Sbjct:   1 ASSTNLKDVLAALIPKEQARIKTFRQQHGGTALGQITVDMSYGGMRGMKGLVYETSVLDP  60

Query:  97 QEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAA 156
            EGIRFRGFSIPECQ+LLP+    GE PLPEGL WLL+TG+IPT +QV  + ++  +RAA
Sbjct:  61 DEGIRFRGFSIPECQKLLPKGGXGGE-PLPEGLFWLLVTGQIPTGAQVSWLSKEWAKRAA 119

Query: 157 VPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTL 216
           +P  V+ +LD  P   +HPM+Q S A++ L  ES  A AYA+G  ++ +WE   E A+ L
Sbjct: 120 LPSHVVTMLDNFP-TNLHPMSQLSAAITALNSESNFARAYAEGILRTKYWEMVYESAMDL 178

Query: 217 IARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVLHA 276
           IA+LP VAA+IYRN +  G  + A  I+   D        LG+   +F ELMRLYL +H+
Sbjct: 179 IAKLPCVAAKIYRNLYRAGSSIGA--IDSKLDWSHNFTNMLGYTDAQFTELMRLYLTIHS 236

Query: 277 DHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRP 336
           DHEGGNVSAH   LVGSALSDPYLSFAA +NGLAGPLHGLANQEVL WL Q+ +K     
Sbjct: 237 DHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPLHGLANQEVLGWLAQL-QKAXXXA 295

Query: 337 MTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSKLYE 396
               +LR+  W TL  G V+PG+GHAVLR+TDPRYT QREFALKHLP D MF+LV++LY+
Sbjct: 296 GADASLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYTCQREFALKHLPGDPMFKLVAQLYK 355

Query: 397 VVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRAL 456
           +VP VL EQG   NPWPNVD HSG+LL+YYG+ E N+YTVLFGVSRALG L+ L+W RAL
Sbjct: 356 IVPNVLLEQGAAANPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLIWSRAL 415

Query: 457 GLPIERPKSVTT 468
           G P+ERPKS++T
Sbjct: 416 GFPLERPKSMST 427


emb|CAE64976.1| Hypothetical protein CBG09810 [Caenorhabditis briggsae]
(468 aa)

Score: 509 bits (1310), Expect: 8.49763e-143
Length: 441, Idn/Pos/Gap = 245/325/7 (55%/73%/1%)

Query:  31 VRALSTSS--ATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMV  88
           V  LSTS+  +T+L+E +  KI    A+V   R   G  V+ +  ++  YGGMRS+K MV
Sbjct:  22 VAPLSTSAEGSTNLKEVLSKKIPAHNAKVKSFRAEHGNTVVQSVNIDMIYGGMRSMKGMV  81

Query:  89 YETSLLDPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVC 148
            ETS+LDP+EGIRFRG+SIPECQ+LLP+AK  GE+PLPE + WLL TG++P+E+Q  ++ 
Sbjct:  82 TETSVLDPEEGIRFRGYSIPECQKLLPKAK-GGEEPLPEAIWWLLCTGDVPSEAQTAAIT 140

Query: 149 QDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEY 208
           ++   RA +P  V+R+LD  P + +HPM QF  A++ L +ESK A AYA+G  K+++WEY
Sbjct: 141 KEWNARADLPTHVVRMLDNFP-DNLHPMAQFIAAIAALNNESKFAGAYARGVAKASYWEY 199

Query: 209 CLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELM 268
             ED++ L+A+LP VAA IYRN +  G  V    I+   D     +  LG++   F ELM
Sbjct: 200 AYEDSMDLLAKLPTVAAIIYRNLYRDGSAVSV--IDPKKDWSANFSSMLGYDDPLFAELM 257

Query: 269 RLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQM 328
           RLYLV+H+DHEGGNVSAH   LVGSALSDPYL+F+A + GLAGPLHGLANQEVL +L ++
Sbjct: 258 RLYLVIHSDHEGGNVSAHTSHLVGSALSDPYLAFSAAMAGLAGPLHGLANQEVLVFLNKI 317

Query: 329 KEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMF 388
             ++G    T E L+E  W+ L+ G V+PG+GHAVLR+TDPRY  QREFALKHLP+D++F
Sbjct: 318 VGEIGFN-YTEEQLKEWVWKHLKSGQVVPGYGHAVLRKTDPRYECQREFALKHLPNDDLF 376

Query: 389 QLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLS 448
           +LVS LY++ P +L EQGK KNPWPNVD HSG+LL+Y+G+ E +FYTVLFGVSRALG LS
Sbjct: 377 KLVSTLYKITPGILLEQGKAKNPWPNVDSHSGVLLQYFGMTEMSFYTVLFGVSRALGCLS 436

Query: 449 SLVWDRALGLPIERPKSVTTQ 469
            L+W R +GLP+ERPKS +T+
Sbjct: 437 QLIWARGMGLPLERPKSHSTE 457


emb|CAA83004.1| Hypothetical protein T20G5.2 [Caenorhabditis elegans]
ref|NP_499264.1| citrate synthase (51.5 kD) (3L304) [Caenorhabditis elegans]
pir||S42370 citrate (si)-synthase (EC 4.1.3.7) precursor - Caenorhabditis elegans
sp|P34575|CISY_CAEEL Probable citrate synthase, mitochondrial precursor
(468 aa)

Score: 508 bits (1309), Expect: 1.33344e-142
Length: 440, Idn/Pos/Gap = 246/323/7 (55%/73%/1%)

Query:  31 VRALSTSS--ATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMV  88
           V  LSTS+  +T+L+E +  KI    A+V   R   G  V+    ++  YGGMRS+K MV
Sbjct:  22 VAPLSTSAEGSTNLKEVLSKKIPAHNAKVKSFRTEHGSTVVQNVNIDMIYGGMRSMKGMV  81

Query:  89 YETSLLDPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVC 148
            ETS+LDP+EGIRFRG+SIPECQ+LLP+AK  GE+PLPE + WLL TG++P+E+Q  ++ 
Sbjct:  82 TETSVLDPEEGIRFRGYSIPECQKLLPKAK-GGEEPLPEAIWWLLCTGDVPSEAQTAAIT 140

Query: 149 QDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEY 208
           ++   RA +P  V+R+LD  P + +HPM QF  A++ L +ESK A AYA+G  K+++WEY
Sbjct: 141 KEWNARADLPTHVVRMLDNFP-DNLHPMAQFIAAIAALNNESKFAGAYARGVAKASYWEY 199

Query: 209 CLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELM 268
             ED++ L+A+LP VAA IYRN +  G  V    I+   D     +  LG++   F ELM
Sbjct: 200 AYEDSMDLLAKLPTVAAIIYRNLYRDGSAVSV--IDPKKDWSANFSSMLGYDDPLFAELM 257

Query: 269 RLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQM 328
           RLYLV+H+DHEGGNVSAH   LVGSALSDPYLSF+A + GLAGPLHGLANQEVL +L ++
Sbjct: 258 RLYLVIHSDHEGGNVSAHTSHLVGSALSDPYLSFSAAMAGLAGPLHGLANQEVLVFLNKI 317

Query: 329 KEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMF 388
             ++G    T E L+E  W+ L+ G V+PG+GHAVLR+TDPRY  QREFALKHLP+D++F
Sbjct: 318 VGEIGFN-YTEEQLKEWVWKHLKSGQVVPGYGHAVLRKTDPRYECQREFALKHLPNDDLF 376

Query: 389 QLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLS 448
           +LVS LY++ P +L EQGK KNPWPNVD HSG+LL+Y+G+ E +FYTVLFGVSRALG LS
Sbjct: 377 KLVSTLYKITPGILLEQGKAKNPWPNVDSHSGVLLQYFGMTEMSFYTVLFGVSRALGCLS 436

Query: 449 SLVWDRALGLPIERPKSVTT 468
            L+W R +GLP+ERPKS +T
Sbjct: 437 QLIWARGMGLPLERPKSHST 456


gb|EAL23399.1| hypothetical protein CNBA0490 [Cryptococcus neoformans var. neoformans B-3501A]
gb|AAW40659.1| citrate synthase, putative [Cryptococcus neoformans var. neoformans JEC21]
ref|XP_566478.1| citrate synthase, putative [Cryptococcus neoformans var. neoformans JEC21]
(464 aa)

Score: 507 bits (1306), Expect: 2.55634e-142
Length: 464, Idn/Pos/Gap = 249/325/7 (53%/70%/1%)

Query:  16 RRAEKSWPSDVWKRAVRALSTSSATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVN  75
           R A +S       R+      + A SL++ +   I      V   R   G + L   TV+
Sbjct:   7 RNALRSQLRPSLARSFATTPAAYAQSLKDRMAELIPQEIENVKATRAAHGAKSLGDVTVD  66

Query:  76 QAYGGMRSLKAMVYETSLLDPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLT 135
            AYGGMR +K +++E S+LDP EGIRFRG +IPECQ+ LP A P G +PLPE L WLLLT
Sbjct:  67 MAYGGMRGIKGLIWEGSVLDPNEGIRFRGLTIPECQQKLPTA-PGGSEPLPEALFWLLLT 125

Query: 136 GEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEA 195
           GE+PT+ QV+ + Q+   RAA+P  V  L+D  P+  +HPMTQF++AV+ L H+S  A+A
Sbjct: 126 GEVPTDEQVKGLSQEWAARAAIPKFVEELIDRCPNT-LHPMTQFAIAVNALNHDSAFAKA 184

Query: 196 YAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLAR 255
           Y+ G  K  +W+   +D++ LIA+LP +A RI+RN F  GK  P   I+   D    LA 
Sbjct: 185 YSNGVHKKEYWKTTFDDSMDLIAKLPNIAGRIFRNVFGDGKLPP---IDPSKDYSANLAT 241

Query: 256 SLGFELN-EFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLH 314
            LGF  N +F ELMRLY+ +H+DHEGGNVSAH   LVGSALSDP+L+F A LNGLAGPLH
Sbjct: 242 LLGFGDNADFVELMRLYITIHSDHEGGNVSAHTGHLVGSALSDPFLAFGASLNGLAGPLH 301

Query: 315 GLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQ 374
           GLANQEVLRW+ +M+ ++G    + E + E  W TL+ G V+PG+GHAVLR+TDPRYTAQ
Sbjct: 302 GLANQEVLRWVQKMRSQIG-EDASDEKVAEYVWSTLKSGQVVPGYGHAVLRKTDPRYTAQ 360

Query: 375 REFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFY 434
           REFALKHLP D +F+LV ++Y++VP +L E GK KNPWPNVD HSG+LL YYGL + +FY
Sbjct: 361 REFALKHLPEDPLFKLVGQIYKIVPNILLEAGKAKNPWPNVDAHSGVLLTYYGLHQQDFY 420

Query: 435 TVLFGVSRALGTLSSLVWDRALGLPIERPKSVTTQWIREHFEKR 478
           TVLFGVSRA G +S L+WDRALG+P+ERPKS +T+ I++ FE +
Sbjct: 421 TVLFGVSRAFGVVSQLIWDRALGMPLERPKSYSTEAIKKMFEGK 464


emb|CAC12961.1| mitochondrial citrate synthase [Podospora anserina]
(472 aa)

Score: 506 bits (1302), Expect: 6.84241e-142
Length: 447, Idn/Pos/Gap = 250/323/15 (55%/72%/3%)

Query:  30 AVRALSTSSAT---SLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKA  86
           A R  S+ + T      E +  KIE ++A    +R+  G +V+D  T++Q YGG R +K 
Sbjct:  30 AARCYSSKTQTLKERFAELLPEKIEEIKA----LRKEHGSKVVDKVTLDQVYGGARGIKC  85

Query:  87 MVYETSLLDPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVES 146
           +V+E S+LD +EGIRFRG +IPECQ++LP+A P G +PLPEGL WLLLTGE+PTE QV  
Sbjct:  86 LVWEGSVLDAEEGIRFRGKTIPECQQVLPKA-PGGSEPLPEGLFWLLLTGEVPTEQQVRD 144

Query: 147 VCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFW 206
           +  D   RA +P  V  L+D  P + +HPM QFS+AV+ L+  S  A AYA+G  K  +W
Sbjct: 145 LSADWAARAEIPKFVEELIDRCPSD-LHPMAQFSMAVTALEQTSSFARAYAKGINKKEYW 203

Query: 207 EYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELN-EFD 265
            Y  ED++ LIA+LP +AARIY+N F GGK  P   ++K  D     A  LGF  N +F 
Sbjct: 204 GYTFEDSMDLIAKLPTIAARIYQNVFKGGKVAP---VQKDKDYSFNFANQLGFGNNADFI 260

Query: 266 ELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWL 325
           ELMRLYL +H DHEGGNVSAH   LVGSALS P+LS AAGLNGLAGPLHGLANQEVL WL
Sbjct: 261 ELMRLYLTIHTDHEGGNVSAHTTHLVGSALSSPFLSLAAGLNGLAGPLHGLANQEVLNWL 320

Query: 326 LQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHD 385
            +MK+ +G+  ++ E++ +  W+TL  G V+PG+GHAVLR+TDPRY+AQREFA KH+  D
Sbjct: 321 TEMKKVIGD-DISDESITKYLWDTLNSGRVVPGYGHAVLRKTDPRYSAQREFAQKHMSED 379

Query: 386 EMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALG 445
            MF+LVS++Y++ P+VL E GK KNP+PNVD HSG+LL+YYGL E+N+YTVLFGVSRA+G
Sbjct: 380 PMFKLVSQVYKIAPKVLTEHGKTKNPYPNVDAHSGVLLQYYGLTEANYYTVLFGVSRAIG 439

Query: 446 TLSSLVWDRALGLPIERPKSVTTQ-WI 471
            L  L+ DRA+G PIERPKS +T+ WI
Sbjct: 440 VLPQLIIDRAVGAPIERPKSFSTEKWI 466


emb|CAA96277.1| CIT1 [Saccharomyces cerevisiae]
emb|CAA80781.1| mitochondrial citrate synthase [Saccharomyces cerevisiae]
emb|CAA54569.1| mitochodrial citrate synthase [Saccharomyces cerevisiae]
pir||YKBY citrate (si)-synthase (EC 4.1.3.7) precursor, mitochondrial - yeast (Saccharomyces cerevisiae)
ref|NP_014398.1| Cit1p [Saccharomyces cerevisiae]
sp|P00890|CISY_YEAST Citrate synthase, mitochondrial precursor
(479 aa)

Score: 505 bits (1300), Expect: 1.35628e-141
Length: 446, Idn/Pos/Gap = 247/324/6 (55%/72%/1%)

Query:  32 RALSTSSATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYET  91
           R  S++S  +L+E     I     ++ + ++  G+ V+    + QAYGGMR +K +V+E 
Sbjct:  35 RHYSSASEQTLKERFAEIIPAKAEEIKKFKKEHGKTVIGEVLLEQAYGGMRGIKGLVWEG  94

Query:  92 SLLDPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDL 151
           S+LDP+EGIRFRG +IPE QR LP+A+ S E PLPE L WLLLTGEIPT++QV+++  DL
Sbjct:  95 SVLDPEEGIRFRGRTIPEIQRELPKAEGSTE-PLPEALFWLLLTGEIPTDAQVKALSADL 153

Query: 152 KRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLE 211
             R+ +P  V++LLD LP + +HPM QFS+AV+ L+ ESK A+AYAQG  K  +W Y  E
Sbjct: 154 AARSEIPEHVIQLLDSLPKD-LHPMAQFSIAVTALESESKFAKAYAQGVSKKEYWSYTFE 212

Query: 212 DALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRLY 271
           D+L L+ +LP +A++IYRN F  GK       +   D G  LA+ LG+E  +F +LMRLY
Sbjct: 213 DSLDLLGKLPVIASKIYRNVFKDGK---ITSTDPNADYGKNLAQLLGYENKDFIDLMRLY 269

Query: 272 LVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEK 331
           L +H+DHEGGNVSAH   LVGSALS PYLS AAGLNGLAGPLHG ANQEVL WL +++E+
Sbjct: 270 LTIHSDHEGGNVSAHTTHLVGSALSSPYLSLAAGLNGLAGPLHGRANQEVLEWLFKLREE 329

Query: 332 LGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLV 391
           +     + E + +  W+TL  G V+PG+GHAVLR+TDPRYTAQREFALKH P  E+F+LV
Sbjct: 330 VKG-DYSKETIEKYLWDTLNAGRVVPGYGHAVLRKTDPRYTAQREFALKHFPDYELFKLV 388

Query: 392 SKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLV 451
           S +YEV P VL + GK KNPWPNVD HSG+LL+YYGL E++FYTVLFGV+RA+G L  L+
Sbjct: 389 STIYEVAPGVLTKHGKTKNPWPNVDSHSGVLLQYYGLTEASFYTVLFGVARAIGVLPQLI 448

Query: 452 WDRALGLPIERPKSVTTQWIREHFEK 477
            DRA+G PIERPKS +T+  +E  +K
Sbjct: 449 IDRAVGAPIERPKSFSTEKYKELVKK 474


gb|AAS50369.1| AAR004Cp [Ashbya gossypii ATCC 10895]
ref|NP_982545.1| AAR004Cp [Eremothecium gossypii]
(477 aa)

Score: 504 bits (1299), Expect: 1.83147e-141
Length: 454, Idn/Pos/Gap = 253/330/9 (55%/72%/1%)

Query:  30 AVRALSTSSATSLQEAVRSKIEPMRAQ-VHEVRERFGEEVLDACTVNQAYGGMRSLKAMV  88
           A RA S     SL+E   ++I P +A+ + + +++ G+ V+    + QAYGGMR +  +V
Sbjct:  32 ACRAYSNGE-KSLKERF-AEIFPAKAEEIKQFKKQHGKVVIGEVLLEQAYGGMRGIPGVV  89

Query:  89 YETSLLDPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVC 148
           +E S+LDP EGIRFRG +IPE Q+ LP+A P+G +PLPE L WLLLTGE+PTE+Q +++ 
Sbjct:  90 WEGSVLDPHEGIRFRGRTIPEVQKELPKA-PNGREPLPEALFWLLLTGEVPTETQTKALS 148

Query: 149 QDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEY 208
            DL  R+ +P  V +LLD LP + +HPM QFSVAV+ L+ ESK A+AYAQG  K  +W Y
Sbjct: 149 ADLMSRSELPGHVEQLLDSLPRD-LHPMAQFSVAVTALESESKFAKAYAQGVSKKDYWNY 207

Query: 209 CLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELM 268
             ED+L L+ +LP +A++IYRN F  GK     KI+   D G  L   LGFE  EF ELM
Sbjct: 208 TFEDSLDLLGKLPVIASKIYRNVFKDGK---MGKIDVDADYGKNLGHLLGFENPEFVELM 264

Query: 269 RLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQM 328
           RLYL +H+DHEGGNVSAH   LVGSALS PYL+FAAG+NGLAGPLHG ANQEVL WL ++
Sbjct: 265 RLYLTVHSDHEGGNVSAHTTHLVGSALSSPYLAFAAGMNGLAGPLHGRANQEVLEWLFKL 324

Query: 329 KEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMF 388
           +E++     + E +R+  W+TL+ G VIPG+GHAVLR+TDPRYTAQREFAL+H P  ++F
Sbjct: 325 REEVKG-DYSPETIRQYLWDTLKGGRVIPGYGHAVLRKTDPRYTAQREFALRHFPDYDLF 383

Query: 389 QLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLS 448
           +LVS +YE+ P+VL E GK KNPWPNVD HSG+LL+YYGL E++FYTVLFGVSRA G L 
Sbjct: 384 KLVSTVYEIAPKVLTEHGKTKNPWPNVDSHSGVLLQYYGLTEASFYTVLFGVSRAFGVLP 443

Query: 449 SLVWDRALGLPIERPKSVTTQWIREHFEKRSVSA 482
            L+ DRA+G PIERPKS +T+  +E    ++  A
Sbjct: 444 QLIIDRAVGAPIERPKSFSTEKFKELVASKASKA 477


gb|AAW27782.1| unknown [Schistosoma japonicum]
(470 aa)

Score: 504 bits (1297), Expect: 3.3119e-141
Length: 444, Idn/Pos/Gap = 243/321/7 (54%/72%/1%)

Query:  28 KRAVRALSTSS--ATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLK  85
           +   R LS +S  + SL++ +   I   +A+V   R+ FG   +   TV+  YGGMR +K
Sbjct:  18 RNVFRQLSLTSVVSASLKDIMADLIPKEQAKVASFRKEFGTTKVGDVTVDMMYGGMRGIK  77

Query:  86 AMVYETSLLDPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVE 145
            +V ETS+LD  EGIRFRG SIP+CQ+ LP+A P G++PLPEG+ +LLLTG++PT++QV+
Sbjct:  78 GLVTETSVLDINEGIRFRGLSIPDCQKQLPKA-PGGQEPLPEGIFFLLLTGKVPTKAQVD 136

Query: 146 SVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTF 205
           ++ ++   RA +P  VL +LD  P   +HPM+Q   A + L  ESK A AY+QG  KS +
Sbjct: 137 NISKEFASRADLPSHVLNMLDSFP-SSLHPMSQLVAACAALNSESKFARAYSQGIKKSVY 195

Query: 206 WEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFD 265
           WEY  ED++ LIA+LP VA+ IYRN +  G  V A  I+   D      R LG+E   F 
Sbjct: 196 WEYVYEDSMDLIAKLPTVASIIYRNLYRDGTSVAA--IDSNTDWSHNFCRMLGYEDPGFT 253

Query: 266 ELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWL 325
           E+MRLYL  H DHEGGNVSAH+  LVGSALSDPYLSFAA + GLAGPLHGLANQEVL +L
Sbjct: 254 EMMRLYLTFHCDHEGGNVSAHSCHLVGSALSDPYLSFAASMCGLAGPLHGLANQEVLVFL 313

Query: 326 LQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHD 385
            +M+EK+G  P T EN+++   +TL  G VIPG+GHAVLR+TDPR+T  +EF  +H P+D
Sbjct: 314 NKMQEKVGKNP-TDENVKQYVMDTLNSGQVIPGYGHAVLRKTDPRFTCAQEFCERHFPND 372

Query: 386 EMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALG 445
            +++LV++LY+VVP +L   GKV+NPWPNVD HSG+LL++YGL E  +YTVLFGVSRALG
Sbjct: 373 PLYKLVAQLYKVVPPILTSLGKVQNPWPNVDAHSGVLLQHYGLTEMQYYTVLFGVSRALG 432

Query: 446 TLSSLVWDRALGLPIERPKSVTTQ 469
            L+SL+WDRALGLPIERPKS++T+
Sbjct: 433 VLASLIWDRALGLPIERPKSLSTE 456


gb|AAM93490.1| citrate synthase [Issatchenkia orientalis]
(456 aa)

Score: 503 bits (1296), Expect: 4.1835e-141
Length: 450, Idn/Pos/Gap = 253/321/7 (56%/71%/1%)

Query:  28 KRAVRALSTSSATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAM  87
           + A RA ST+  T L+E     +   +A+V E++ + G+ V+    + QAYGGMR +K +
Sbjct:   8 RSATRAYSTAEPT-LKERFAELLPGWQAEVKELKSKHGKTVIGEVLLEQAYGGMRGIKGL  66

Query:  88 VYETSLLDPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESV 147
           V+E S+LDP EGIRFRG +IP+ Q+ LP+A+ S E PLPE L WLLLTGE+PT +Q ++ 
Sbjct:  67 VWEGSVLDPVEGIRFRGKTIPDIQKELPKAEGSSE-PLPEALFWLLLTGEVPTLAQTKAF 125

Query: 148 CQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWE 207
             +L  R+A+P  V  LLD  P   +HPM QFS+A++ L+ ESK A+AYA G  K  +W+
Sbjct: 126 SAELASRSALPKHVEDLLDTCP-TTLHPMAQFSIAINALESESKFAKAYADGVNKKEYWK 184

Query: 208 YCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELN-EFDE 266
           Y  ED++ L+A+LP VAA+IYRN F  GK  P   +    D     A  LGF  N EF E
Sbjct: 185 YTYEDSIDLLAKLPNVAAKIYRNVFKDGKVAP---VNASLDYSHNFANMLGFGDNKEFVE 241

Query: 267 LMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLL 326
           LMRLYL +H+DHEGGNVSAH   LVGSALS PYLS AAG+NGLAGPLHG ANQEVL WL+
Sbjct: 242 LMRLYLSIHSDHEGGNVSAHTTHLVGSALSSPYLSLAAGMNGLAGPLHGRANQEVLEWLV 301

Query: 327 QMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDE 386
            MK++LG+     E + E  W+TL  G V+PG+GHAVLR+TDPRYTAQREFALKH+P  +
Sbjct: 302 GMKKELGDDIFNKEKIEEYLWKTLNAGRVVPGYGHAVLRKTDPRYTAQREFALKHMPDYD 361

Query: 387 MFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGT 446
           MF+LVS +YEV P+VL EQGK KNPWPNVD HSGILL+YYGL + ++YTVLFGV+RA G 
Sbjct: 362 MFKLVSNIYEVAPKVLAEQGKTKNPWPNVDSHSGILLQYYGLTQESYYTVLFGVARAFGV 421

Query: 447 LSSLVWDRALGLPIERPKSVTTQWIREHFE 476
           L  L+ DR LG+ IERPKS +TQ  +E  E
Sbjct: 422 LPQLIIDRGLGMAIERPKSFSTQKYKELVE 451


gb|AAO32374.1| CIT1 [Saccharomyces bayanus]
(479 aa)

Score: 502 bits (1293), Expect: 8.08738e-141
Length: 471, Idn/Pos/Gap = 251/332/12 (53%/70%/2%)

Query:  10 LGRRDLRRAEKSWPSDVWKRAVRALSTSSATSLQEAVRSKIEPMRAQVHEVRERFGEEVL  69
           L R   R+ + +  +     + R  S+++  +L+E     I     ++ + ++  G+ V+
Sbjct:  13 LSRNPARQCQSAQKALFALLSSRHYSSATEQTLKERFAEIIPAKAEEIKKFKKEHGKTVI  72

Query:  70 DACTVNQAYGGMRSLKAMVYETSLLDPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGL 129
               + QAYGGMR +K +V+E S+LDP EGIRFRG +IPE QR LP+A+ S E PLPE L
Sbjct:  73 GEVLLEQAYGGMRGIKGLVWEGSVLDPDEGIRFRGRTIPEIQRELPKAEGSTE-PLPEAL 131

Query: 130 LWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHE 189
            WLLLTGEIPT++QV+++  DL  R+ +P  V++LLD LP + +HPM QFS+AV+ L+ E
Sbjct: 132 FWLLLTGEIPTDAQVKALSADLAARSEIPEHVVQLLDSLPKD-LHPMAQFSIAVTALESE 190

Query: 190 SKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVD-- 247
           SK A+AYAQG  K  +W Y  ED+L L+ +LP +A++IYRN F  GK      I  VD  
Sbjct: 191 SKFAKAYAQGVSKKEYWSYTFEDSLDLLGKLPVIASKIYRNVFKDGK------ITTVDPN 244

Query: 248 -DMGMRLARSLGFELNEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGL 306
            D G  LA+ LG+E  +F +LMRLYL +H+DHEGGNVSAH   LVGSALS PYLS AAGL
Sbjct: 245 ADYGKNLAQLLGYENKDFVDLMRLYLTIHSDHEGGNVSAHTTHLVGSALSSPYLSLAAGL 304

Query: 307 NGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRR 366
           NGLAGPLHG ANQEVL WL +++E++     + E + +  WETL  G V+PG+GHAVLR+
Sbjct: 305 NGLAGPLHGRANQEVLEWLFKLREEVKG-DYSKETIEKYLWETLNSGRVVPGYGHAVLRK 363

Query: 367 TDPRYTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYY 426
           TDPRY AQREFALKH P  E+F+LVS +Y+V P VL + GK KNPWPNVD HSG+LL+YY
Sbjct: 364 TDPRYMAQREFALKHFPDYELFKLVSTIYDVAPGVLTKHGKTKNPWPNVDSHSGVLLQYY 423

Query: 427 GLVESNFYTVLFGVSRALGTLSSLVWDRALGLPIERPKSVTTQWIREHFEK 477
           GL E++FYTVLFGV+RA+G L  L+ DRA+G PIERPKS +T+  +E  +K
Sbjct: 424 GLTEASFYTVLFGVARAIGVLPQLIIDRAVGAPIERPKSFSTEKYKELVKK 474


emb|CAG59901.1| unnamed protein product [Candida glabrata CBS138]
ref|XP_446968.1| unnamed protein product [Candida glabrata]
(472 aa)

Score: 501 bits (1291), Expect: 1.36804e-140
Length: 445, Idn/Pos/Gap = 245/317/6 (55%/71%/1%)

Query:  29 RAVRALSTSSATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMV  88
           RA  A S SS  +L++           ++ + ++  G+ V+D   + QAYGGMR +K +V
Sbjct:  25 RAFSATSISSEKTLKDTFADIFPKQAEEIKQFKKEHGKTVIDQLLLEQAYGGMRGIKGIV  84

Query:  89 YETSLLDPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVC 148
           +E S+LDP+EGIRFRG +IPE ++ LP    S E P+PE L WLLLTGE+PTESQV++  
Sbjct:  85 WEGSVLDPEEGIRFRGRTIPEIKKELPTIGGSSE-PVPEALFWLLLTGEVPTESQVKAFS 143

Query: 149 QDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEY 208
            DL  R+ VP  VL+LLD LP + +HPM Q S+AV+ L+ ESK A+AYA+G  K  +W Y
Sbjct: 144 ADLASRSEVPEHVLKLLDSLPKD-LHPMAQLSIAVNALETESKFAKAYARGVNKKEYWSY 202

Query: 209 CLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELM 268
             ED+L L+ +LP +A++IYRN F  GK     +++   D G  LA  LG+   +F +LM
Sbjct: 203 TFEDSLDLLGKLPVIASKIYRNIFKDGKIC---QVDPNADYGKNLAHLLGYTNKDFVDLM 259

Query: 269 RLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQM 328
           RLYL +H+DHEGGNVSAH   LVGSALS PYLSFAAG+NGLAGPLHG ANQEVL WL   
Sbjct: 260 RLYLTIHSDHEGGNVSAHTTHLVGSALSSPYLSFAAGMNGLAGPLHGRANQEVLEWLFTF 319

Query: 329 KEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMF 388
           +E++     + E + +  W+TL  G VIPG+GHAVLR+TDPRYTAQREFALKH P  E+F
Sbjct: 320 REEVKG-DYSKETVEKYLWDTLNGGRVIPGYGHAVLRKTDPRYTAQREFALKHFPDYELF 378

Query: 389 QLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLS 448
           +LVS +Y+V P+VL + GK KNPWPNVD HSG+LL+YYGL E++FYTVLFGVSRA G L 
Sbjct: 379 KLVSTIYDVAPKVLTKHGKTKNPWPNVDSHSGVLLQYYGLTEASFYTVLFGVSRAFGVLP 438

Query: 449 SLVWDRALGLPIERPKSVTTQWIRE 473
            L+ DRA+G PIERPKS +T+  +E
Sbjct: 439 QLIIDRAVGAPIERPKSFSTEKFKE 463


emb|CAA25359.1| unnamed protein product [Saccharomyces cerevisiae]
(480 aa)

Score: 501 bits (1289), Expect: 2.21957e-140
Length: 448, Idn/Pos/Gap = 250/329/9 (55%/73%/2%)

Query:  32 RALSTSSATSLQEAVRSKIEPMRAQ-VHEVRERFGEEVLDACTVN-QAYGGMRSLKAMVY  89
           R  S++S  +L+E   ++I P +AQ + + ++  G+ V+    +  QAYGGMR +K +V+
Sbjct:  35 RHYSSASEQTLKERF-AEIIPAKAQEIKKFKKEHGKTVIGEVLLEEQAYGGMRGIKGLVW  93

Query:  90 ETSLLDPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQ 149
           E S+LDP+EGIRFRG +IPE QR LP+A+ S E PLPE L WLLLTGEIPT++QV+++  
Sbjct:  94 EGSVLDPEEGIRFRGRTIPEIQRELPKAEGSTE-PLPEALFWLLLTGEIPTDAQVKALSA 152

Query: 150 DLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYC 209
           DL  R+ +P  V++LLD LP + +HPM QFS+AV+ L+ ESK A+AYAQG  K  +W Y 
Sbjct: 153 DLAARSEIPEHVIQLLDSLPKD-LHPMAQFSIAVTALESESKFAKAYAQGVSKKEYWSYT 211

Query: 210 LEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMR 269
            ED+L L+ +LP +A++IYRN F  GK       +   D G  LA+ LG+E  +F +LMR
Sbjct: 212 FEDSLDLLGKLPVIASKIYRNVFKDGK---ITSTDPNADYGKNLAQLLGYENKDFIDLMR 268

Query: 270 LYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMK 329
           LYL +H+DHEGGNVSAH   LVGSALS PYLS AAGLNGLAGPLHG ANQEVL WL +++
Sbjct: 269 LYLTIHSDHEGGNVSAHTTHLVGSALSSPYLSLAAGLNGLAGPLHGRANQEVLEWLFKLR 328

Query: 330 EKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQ 389
           E++     + E + +  W+TL  G V+PG+GHAVLR+TDPRYTAQREFALKH P  E+F+
Sbjct: 329 EEVKG-DYSKETIEKYLWDTLNAGRVVPGYGHAVLRKTDPRYTAQREFALKHFPDYELFK 387

Query: 390 LVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSS 449
           LVS +YEV P VL + GK KNPWPNVD HSG+LL+YYGL E++FYTVLFGV+RA+G L  
Sbjct: 388 LVSTIYEVAPGVLTKHGKTKNPWPNVDSHSGVLLQYYGLTEASFYTVLFGVARAIGVLPQ 447

Query: 450 LVWDRALGLPIERPKSVTTQWIREHFEK 477
           L+ DRA+G PIERPKS +T+  +E  +K
Sbjct: 448 LIIDRAVGAPIERPKSFSTEKYKELVKK 475


emb|CAG79048.1| unnamed protein product [Yarrowia lipolytica CLIB99]
ref|XP_503469.1| hypothetical protein [Yarrowia lipolytica]
(465 aa)

Score: 497 bits (1279), Expect: 3.57225e-139
Length: 441, Idn/Pos/Gap = 245/318/8 (55%/72%/1%)

Query:  30 AVRALSTSSATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVY  89
           A RA ST     L+E     I     ++ ++R+  G  V+    ++QAYGGMR +K +V+
Sbjct:  22 AFRAYSTQDG--LKERFAELIPENVEKIKKLRKEKGNTVIGEVILDQAYGGMRGIKGLVW  79

Query:  90 ETSLLDPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQ 149
           E S+LDP+EGIRFRG +IP+ Q+ LP A P G++PLPEGL WLLLTGEIPT++QV+ +  
Sbjct:  80 EGSVLDPEEGIRFRGLTIPDLQKQLPHA-PGGKEPLPEGLFWLLLTGEIPTDAQVKGLSA 138

Query: 150 DLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYC 209
           D   RA +P  V  L+D  P   +HPM Q  +AV+ L+ ES+  +AY +G  K  +W+Y 
Sbjct: 139 DWASRAEIPKHVEELIDRCP-PTLHPMAQLGIAVNALESESQFTKAYEKGVNKKEYWQYT 197

Query: 210 LEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELN-EFDELM 268
            ED++ LIA+LP +A+RIYRN F  GK V +  I+   D     A  LGF  N EF EL+
Sbjct: 198 YEDSMNLIAKLPVIASRIYRNLFKDGKIVGS--IDNSLDYSANFASLLGFGDNKEFIELL 255

Query: 269 RLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQM 328
           RLYL +HADHEGGNVSAH  +LVGSALS P+LS +AGLNGLAGPLHG ANQEVL W+L+M
Sbjct: 256 RLYLTIHADHEGGNVSAHTTKLVGSALSSPFLSLSAGLNGLAGPLHGRANQEVLEWILEM 315

Query: 329 KEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMF 388
           K K+G+  +T E++ +  W+TL+ G V+PG+GHAVLR+TDPRYTAQREFAL+H+P  ++F
Sbjct: 316 KSKIGS-DVTKEDIEKYLWDTLKAGRVVPGYGHAVLRKTDPRYTAQREFALEHMPDYDLF 374

Query: 389 QLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLS 448
            LVS +YEV P+VL E GK KNPWPNVD HSG+LL+YYGL E ++YTVLFGVSRA+G L 
Sbjct: 375 HLVSTIYEVAPKVLTEHGKTKNPWPNVDSHSGVLLQYYGLTEQSYYTVLFGVSRAIGVLP 434

Query: 449 SLVWDRALGLPIERPKSVTTQ 469
            L+ DRA G PIERPKS +T+
Sbjct: 435 QLIMDRAYGAPIERPKSFSTE 455


gb|AAP31957.1| At2g44350 [Arabidopsis thaliana]
gb|AAC16084.2| citrate synthase [Arabidopsis thaliana]
gb|AAK62463.1| citrate synthase [Arabidopsis thaliana]
ref|NP_566016.1| citrate synthase, mitochondrial, putative [Arabidopsis thaliana]
(473 aa)

Score: 497 bits (1279), Expect: 3.8831e-139
Length: 477, Idn/Pos/Gap = 263/331/12 (55%/69%/2%)

Query:   5 RFVLALGRRDLRRAEKSWPSDVWKRAVRALSTSSATSL--QEAVRSKIEPMRAQVHEVRE  62
           R V A  R   R  ++S  S+    +VR +   S+T L  +  ++  I   + ++ +++ 
Sbjct:   5 RSVSAFTRLRSRVGQQSSLSN----SVRWIQMQSSTDLDLKSQLQELIPEQQDRLKKLKS  60

Query:  63 RFGEEVLDACTVNQAYGGMRSLKAMVYETSLLDPQEGIRFRGFSIPECQRLLPRAKPSGE 122
             G+  L   TV+   GGMR +  +++ETSLLDP+EGIRFRG SIPECQ++LP A+ SG 
Sbjct:  61 EHGKVQLGNITVDMVIGGMRGMTGLLWETSLLDPEEGIRFRGLSIPECQKVLPTAQ-SGA 119

Query: 123 QPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVA 182
           +PLPEGLLWLLLTG++P++ QVE++ +DL  RAAVP  V   +D LP    HPMTQF+  
Sbjct: 120 EPLPEGLLWLLLTGKVPSKEQVEALSKDLANRAAVPDYVYNAIDALP-STAHPMTQFASG 178

Query: 183 VSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEK 242
           V  LQ +S+  +AY  G  KS FWE   ED L LIAR+P VAA +YR  +  G  +P++K
Sbjct: 179 VMALQVQSEFQKAYENGIHKSKFWEPTYEDCLNLIARVPVVAAYVYRRMYKNGDSIPSDK 238

Query: 243 IEKVDDMGMRLARSLGFELNEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSF 302
                D G   +  LGF+  +  ELMRLY+ +H+DHEGGNVSAH   LVGSALSDPYLSF
Sbjct: 239 SL---DYGANFSHMLGFDDEKVKELMRLYITIHSDHEGGNVSAHTGHLVGSALSDPYLSF 295

Query: 303 AAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHA 362
           AA LNGLAGPLHGLANQEVL W+  + E+ G   ++ E L+E  W+TL  G VIPG+GH 
Sbjct: 296 AAALNGLAGPLHGLANQEVLLWIKSVVEECG-EDISKEQLKEYVWKTLNSGKVIPGYGHG 354

Query: 363 VLRRTDPRYTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGIL 422
           VLR TDPRY  QREFALKHLP D +FQLVSKLYEVVP VL E GKVKNPWPNVD HSG+L
Sbjct: 355 VLRNTDPRYVCQREFALKHLPDDPLFQLVSKLYEVVPPVLTELGKVKNPWPNVDAHSGVL 414

Query: 423 LRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLPIERPKSVTTQWIREHFEKRS 479
           L +YGL E+ +YTVLFGVSR+LG  S L+WDRALGL +ERPKSVT  W+  H +K S
Sbjct: 415 LNHYGLTEARYYTVLFGVSRSLGICSQLIWDRALGLALERPKSVTMDWLEAHCKKAS 471


gb|AAM62868.1| citrate synthase [Arabidopsis thaliana]
(473 aa)

Score: 496 bits (1278), Expect: 5.20004e-139
Length: 452, Idn/Pos/Gap = 256/321/8 (56%/71%/1%)

Query:  30 AVRALSTSSATSL--QEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAM  87
           +VR +   S+T L  +  ++  I   + ++ +++   G+  L   TV+   GGMR +  +
Sbjct:  26 SVRWIQMQSSTDLDLKSQLQELIPEQQDRLKKLKSEHGKVQLGNITVDMVIGGMRGMTGL  85

Query:  88 VYETSLLDPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESV 147
           ++ETSLLDP+EGIRFRG SIPECQ++LP A+ SG +PLPEGLLWLLLTG++P++ QVE++
Sbjct:  86 LWETSLLDPEEGIRFRGLSIPECQKVLPTAQ-SGAEPLPEGLLWLLLTGKVPSKEQVEAL 144

Query: 148 CQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWE 207
            +DL  RAAVP  V   +D LP    HPMTQF+  V  LQ +S+  +AY  G  KS FWE
Sbjct: 145 SKDLANRAAVPDYVYNAIDALP-STAHPMTQFASGVMALQVQSEFQKAYENGIHKSKFWE 203

Query: 208 YCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDEL 267
              ED L LIAR+P VAA +YR  +  G  +P++K     D G   +  LGF+  +  EL
Sbjct: 204 PTYEDCLNLIARVPVVAAYVYRRMYKNGDSIPSDKSL---DYGANFSHMLGFDDEKVKEL 260

Query: 268 MRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQ 327
           MRLY+ +H+DHEGGNVSAH   LVGSALSDPYLSFAA LNGLAGPLHGLANQEVL W+  
Sbjct: 261 MRLYITIHSDHEGGNVSAHTGHLVGSALSDPYLSFAAALNGLAGPLHGLANQEVLLWIKS 320

Query: 328 MKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEM 387
           + E+ G   ++ E L+E  W+TL  G VIPG+GH VLR TDPRY  QREFALKHLP D +
Sbjct: 321 VVEECG-EDISKEQLKEYVWKTLNSGKVIPGYGHGVLRNTDPRYVCQREFALKHLPDDPL 379

Query: 388 FQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTL 447
           FQLVSKLYEVVP VL E GKVKNPWPNVD HSG+LL +YGL E+ +YTVLFGVSR+LG  
Sbjct: 380 FQLVSKLYEVVPPVLTELGKVKNPWPNVDAHSGVLLNHYGLTEARYYTVLFGVSRSLGIC 439

Query: 448 SSLVWDRALGLPIERPKSVTTQWIREHFEKRS 479
           S L+WDRALGL +ERPKSVT  W+  H +K S
Sbjct: 440 SQLIWDRALGLALERPKSVTMDWLEAHCKKAS 471


emb|CAA93617.2| SPAC6C3.04 [Schizosaccharomyces pombe]
ref|NP_593718.1| citrate synthase, mitochondrial precursor [Schizosaccharomyces pombe]
pir||T39028 citrate synthase precursor, mitochondrial - fission yeast  (Schizosaccharomyces pombe)
sp|Q10306|CISY_SCHPO Probable citrate synthase, mitochondrial precursor
(473 aa)

Score: 496 bits (1278), Expect: 5.20004e-139
Length: 438, Idn/Pos/Gap = 245/320/7 (55%/73%/1%)

Query:  42 LQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYETSLLDPQEGIR 101
           L++ +   I   +A++ + R   G++V+   T+NQ YGG R ++++++E S+LDP EGIR
Sbjct:  42 LKDRLAELIPEKQAEIKKFRAEHGQDVIGEVTINQMYGGARGVRSLIWEGSVLDPNEGIR 101

Query: 102 FRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEV 161
           FRG++IPECQ+LLP + P+G+QPLPE L WLL+TGEIPT SQV+++  D   R+ +P  V
Sbjct: 102 FRGYTIPECQKLLP-SSPNGKQPLPESLFWLLVTGEIPTLSQVQALSADWAARSQLPKFV 160

Query: 162 LRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLP 221
             L+D  P   +HPM QFS+AV+ L+H+S  A+AY +G  K  +W+Y  ED + LIA+  
Sbjct: 161 EELIDRCP-PTLHPMAQFSLAVTALEHDSAFAKAYERGMNKHDYWKYEYEDCMDLIAKTV 219

Query: 222 AVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNE-FDELMRLYLVLHADHEG 280
            +A RIYRN +  G   P   I+   D     A  LGF  NE F ELMRLYL +HADHEG
Sbjct: 220 PIAGRIYRNLYRDGVVAP---IQMDKDHSYNFANVLGFANNEEFVELMRLYLTIHADHEG 276

Query: 281 GNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTE 340
           GNVSAH   LVGSALS P+LS AA LNGLAGPLHGLANQEVL +L+ MK+++G+  ++ E
Sbjct: 277 GNVSAHTGHLVGSALSSPFLSMAASLNGLAGPLHGLANQEVLNFLITMKKEIGD-DLSEE 335

Query: 341 NLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSKLYEVVPR 400
            ++   W+ L  G V+PG+GHAVLR+TDPRYTAQREFAL+HLP D MFQLVS+LYE+VP 
Sbjct: 336 TIKSYLWKLLNSGRVVPGYGHAVLRKTDPRYTAQREFALEHLPKDPMFQLVSRLYEIVPG 395

Query: 401 VLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLPI 460
           VL E GK KNP+PNVD HSG+LL+YYGL E +FYTVLFGVSR LG  S L+WDRALGLPI
Sbjct: 396 VLTEHGKTKNPYPNVDSHSGVLLQYYGLKEQSFYTVLFGVSRTLGVASQLIWDRALGLPI 455

Query: 461 ERPKSVTTQWIREHFEKR 478
           ERPKS +T+ +++  E +
Sbjct: 456 ERPKSFSTEALKKMVETK 473


emb|CAB91282.1| mitochondrial citrate synthase [Neurospora crassa]
ref|XP_328131.1| citrate synthase, mitochondrial [MIPS] [Neurospora crassa]
pir||T49379 citrate synthase, mitochondrial [imported] - Neurospora crassa
gb|EAA27662.1| citrate synthase, mitochondrial [MIPS] [Neurospora crassa]
sp|P34085|CISY_NEUCR Citrate synthase, mitochondrial precursor
(469 aa)

Score: 496 bits (1278), Expect: 5.37652e-139
Length: 470, Idn/Pos/Gap = 250/328/15 (53%/69%/3%)

Query:   7 VLALGRRDLRRAEKSWPSDVWKRAVRALSTSSAT---SLQEAVRSKIEPMRAQVHEVRER  63
           V+ LG   LR +           A R  S+ + T      E +   IE ++A    +R+ 
Sbjct:   4 VMRLGSAALRSSIHLTSRQTAFTAARCYSSKTQTLKERFAELLPENIEKIKA----LRKE  59

Query:  64 FGEEVLDACTVNQAYGGMRSLKAMVYETSLLDPQEGIRFRGFSIPECQRLLPRAKPSGEQ 123
            G +V+D  T++Q YGG R +K +V+E S+LD +EGIRFRG +IPECQ LLP+A P G++
Sbjct:  60 HGSKVVDKVTLDQVYGGARGIKCLVWEGSVLDAEEGIRFRGKTIPECQELLPKA-PGGKE 118

Query: 124 PLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAV 183
           PLPEGL WLLLTGE+P+E QV  +  +   R+ VP  +  L+D  P + +HPM Q S+AV
Sbjct: 119 PLPEGLFWLLLTGEVPSEQQVRDLSAEWAARSDVPKFIEELIDRCPSD-LHPMAQLSLAV 177

Query: 184 SLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKI 243
           + L+H S  A AYA+G  K  +W Y  ED++ LIA+LP +AARIY+N F GGK      +
Sbjct: 178 TALEHTSSFARAYAKGINKKEYWGYTFEDSMDLIAKLPTIAARIYQNVFKGGK---VAAV 234

Query: 244 EKVDDMGMRLARSLGFELN-EFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSF 302
           +K  D     A  LGF  N +F EL+RLYL +H DHEGGNVSAH   LVGSALS P+LS 
Sbjct: 235 QKDKDYSFNFANQLGFGDNKDFVELLRLYLTIHTDHEGGNVSAHTTHLVGSALSSPFLSV 294

Query: 303 AAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHA 362
           AAGLNGLAGPLHGLANQEVL WL +MK+ +G+  ++ E + +  W+TL  G V+PG+GHA
Sbjct: 295 AAGLNGLAGPLHGLANQEVLNWLTEMKKVIGD-DLSDEAITKYLWDTLNAGRVVPGYGHA 353

Query: 363 VLRRTDPRYTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGIL 422
           VLR+TDPRY+AQR+FA +HLP D MFQLVS++Y++ P+VL E GK KNP+PNVD HSG+L
Sbjct: 354 VLRKTDPRYSAQRKFAQEHLPEDPMFQLVSQVYKIAPKVLTEHGKTKNPYPNVDAHSGVL 413

Query: 423 LRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLPIERPKSVTT-QWI 471
           L++YGL E+N+YTVLFGVSRA+G L  L+ DRA+G PIERPKS +T +WI
Sbjct: 414 LQHYGLTEANYYTVLFGVSRAIGVLPQLIIDRAVGAPIERPKSYSTDKWI 463


gb|AAO32482.1| CIT1 [Saccharomyces castellii]
(476 aa)

Score: 496 bits (1277), Expect: 6.73503e-139
Length: 443, Idn/Pos/Gap = 244/319/9 (55%/72%/2%)

Query:  32 RALSTSSAT-SLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYE  90
           R  +T+SA  +L+E     I     ++ + ++  G+ V+    + QAYGGMR +K +V+E
Sbjct:  29 RLYTTASAEPTLKETFSQLIPSKIDEIKQFKKDHGKTVIGNVLLEQAYGGMRGIKGIVWE  88

Query:  91 TSLLDPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQD 150
            S+LDP+EGI+FRG +IPE +  LP+    G++PLPEG+ WLLLTGEIP+ +QVE +  D
Sbjct:  89 GSVLDPEEGIKFRGLTIPEIRDQLPKL---GDEPLPEGIFWLLLTGEIPSRAQVEQLSAD 145

Query: 151 LKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCL 210
           L  RA +P  V+ LL+ LP + +HPM QFS+AV+ L+ ESK A+AYAQG  K  +W+Y  
Sbjct: 146 LASRAELPEHVVNLLNGLP-KHLHPMAQFSIAVNALESESKFAKAYAQGVNKKEYWKYTF 204

Query: 211 EDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRL 270
           ED+L L+ +LP +AA IYRN F  GK       +   D G  LA  +GF+  +F ELMRL
Sbjct: 205 EDSLDLLGKLPTIAATIYRNVFKDGK---LGAWDPQADYGKNLATLMGFKNKDFMELMRL 261

Query: 271 YLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKE 330
           YL +H+DHEGGNVSAH   LVGSALS PYLS AAGLNGLAGPLHG ANQEVL WL +++E
Sbjct: 262 YLTIHSDHEGGNVSAHTTHLVGSALSSPYLSLAAGLNGLAGPLHGRANQEVLEWLFKLRE 321

Query: 331 KLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQL 390
           ++     + E + +  W+TL  G V+PG+GHAVLR+TDPRYTAQREFALKH P  E+F+L
Sbjct: 322 EVKG-DYSKETIEKYLWDTLNSGRVVPGYGHAVLRKTDPRYTAQREFALKHFPDYELFKL 380

Query: 391 VSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSL 450
           VS +YEV P+VL +QGK KNPWPNVD HSG+LL+YYGL E++FYTVLFGV+RA G L  L
Sbjct: 381 VSSIYEVAPKVLTKQGKTKNPWPNVDSHSGVLLQYYGLTEASFYTVLFGVARAFGVLPQL 440

Query: 451 VWDRALGLPIERPKSVTTQWIRE 473
           + DRA+G PIERPKS +T+  +E
Sbjct: 441 IIDRAVGAPIERPKSFSTEKYKE 463


emb|CAG98363.1| unnamed protein product [Kluyveromyces lactis NRRL Y-1140]
gb|AAO32612.1| CIT1 [Kluyveromyces lactis]
ref|XP_455655.1| unnamed protein product [Kluyveromyces lactis]
(482 aa)

Score: 496 bits (1276), Expect: 8.15987e-139
Length: 425, Idn/Pos/Gap = 241/315/11 (56%/74%/2%)

Query:  48 SKIEPMRAQ-VHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYETSLLDPQEGIRFRGFS 106
           ++I P +A+ +  +++  G+ V+    + QAYGGMR +K +V+E S+LDP+EGIRFRG +
Sbjct:  53 AEIFPEKAEEIKRLKKEHGKTVIGEVLLEQAYGGMRGIKGLVWEGSVLDPEEGIRFRGRT 112

Query: 107 IPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLD 166
           IP+ Q+ LP+A   GE+PLPE + WLLLTGE+PTE+QV+++  DL  R+ +P  V  LLD
Sbjct: 113 IPDIQKELPKAA-DGEEPLPEAIFWLLLTGEVPTETQVKALSADLASRSELPAHVESLLD 171

Query: 167 ELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAAR 226
            LP + +HPM QFS+AV+ L+ ESK A+AYAQG  K  +W Y  ED+L L+ +LP +A++
Sbjct: 172 NLPKD-LHPMAQFSMAVTALESESKFAKAYAQGVSKKDYWNYTFEDSLDLLGKLPVIASK 230

Query: 227 IYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVLHADHEGGNVSAH 286
           IYRN F  GK      I++  D G  LA  LG++  EF +LMRLYL +H+DHEGGNVSAH
Sbjct: 231 IYRNVFKDGK---ITSIDQNADYGKNLAHLLGYQNKEFVDLMRLYLTIHSDHEGGNVSAH 287

Query: 287 AVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGN--RPMTTENLRE 344
              LVGSALS PYLS +AGLNGLAGPLHG ANQEVL WL +++E++     P T E   +
Sbjct: 288 TTHLVGSALSSPYLSLSAGLNGLAGPLHGRANQEVLEWLFKLREEVKGDYSPATIE---K 344

Query: 345 LCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEE 404
             W+TL  G V+PG+GHAVLR+TDPRYTAQREFALKH P  E+F+LVS +YEV P+VL +
Sbjct: 345 YLWDTLNSGRVVPGYGHAVLRKTDPRYTAQREFALKHFPDYELFKLVSTIYEVAPKVLTK 404

Query: 405 QGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLPIERPK 464
            GK KNPWPNVD HSG+LL+YYGL E++FYTVLFGV+RA G L  L+ DRA+G PIERPK
Sbjct: 405 HGKTKNPWPNVDSHSGVLLQYYGLTEASFYTVLFGVARAFGVLPQLIIDRAVGQPIERPK 464

Query: 465 SVTTQ 469
           S +T+
Sbjct: 465 SFSTE 469


gb|AAF78896.1| putative citrate synthase [Saccharomyces kluyveri]
(475 aa)

Score: 496 bits (1276), Expect: 8.3667e-139
Length: 423, Idn/Pos/Gap = 238/313/7 (56%/73%/1%)

Query:  48 SKIEPMRAQ-VHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYETSLLDPQEGIRFRGFS 106
           ++I P +A+ + ++++  G+ V+    + QAYGGMR +K +V+E S+LDP+EGIRFRG +
Sbjct:  46 AEIFPSKAEEIKKLKKEHGKTVIGEVLLEQAYGGMRGIKGLVWEGSVLDPEEGIRFRGRT 105

Query: 107 IPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLD 166
           IPE Q+ LP+A   G +PLPE + WLLLTGEIPTE+QV+++  DL  R+ +P  V+ LLD
Sbjct: 106 IPEIQKELPKAA-DGSEPLPEAIFWLLLTGEIPTETQVKALSADLASRSELPEHVVDLLD 164

Query: 167 ELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAAR 226
            LP + +HPM QFS+AV+ L+ ESK+ +AYAQG  K  +W Y  ED+L L+ +LP +A++
Sbjct: 165 RLPKD-LHPMAQFSIAVTALESESKLPKAYAQGVAKKDYWNYTFEDSLDLLGKLPVIASK 223

Query: 227 IYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVLHADHEGGNVSAH 286
           IYRN F  GK      ++   D G  LA  LGF+  +F +LMRLYL +H+DHEGGNVSAH
Sbjct: 224 IYRNVFKDGK---LASVDPNADYGKNLANLLGFQNKDFVDLMRLYLTIHSDHEGGNVSAH 280

Query: 287 AVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELC 346
              LVGSALS PYLS AAGLNGLAGP  G ANQEVL WL +++E++     + E + +  
Sbjct: 281 TTHLVGSALSSPYLSLAAGLNGLAGPFDGRANQEVLEWLFKLREEVKG-DYSKETIEKYL 339

Query: 347 WETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQG 406
           W+TL  G V+PG+GHAVLR+TDPRYTAQREFALKH P  E+F+LVS +YEV P VL +QG
Sbjct: 340 WDTLNSGRVVPGYGHAVLRKTDPRYTAQREFALKHFPDYELFKLVSTIYEVAPGVLTKQG 399

Query: 407 KVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLPIERPKSV 466
           K KNPWPNVD HSG+LL+YYGL E++FYTVLFGV+RA G L  L+ DRA+G PIERPKS 
Sbjct: 400 KTKNPWPNVDSHSGVLLQYYGLTEASFYTVLFGVARAFGVLPQLIIDRAVGQPIERPKSF 459

Query: 467 TTQ 469
           +T+
Sbjct: 460 STE 462


gb|EAA67397.1| CISY_NEUCR Citrate synthase, mitochondrial precursor [Gibberella zeae PH-1]
ref|XP_381598.1| CISY_NEUCR Citrate synthase, mitochondrial precursor [Gibberella zeae PH-1]
(470 aa)

Score: 496 bits (1276), Expect: 8.50749e-139
Length: 446, Idn/Pos/Gap = 247/318/15 (55%/71%/3%)

Query:  30 AVRALSTSSAT---SLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKA  86
           A+R  S  + T      E +  KIE    QV  +R+  G +V+D  T++Q YGG R +KA
Sbjct:  28 AIRCYSAKTQTLKERFAELLPEKIE----QVKALRKEHGSKVVDKVTLDQVYGGARGIKA  83

Query:  87 MVYETSLLDPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVES 146
           +V+E S+LD +EGIRFRG +IPECQ LLP+A P G++PLPEGL WLLLTGE+PTE QV  
Sbjct:  84 LVWEGSVLDSEEGIRFRGKTIPECQELLPKA-PGGKEPLPEGLFWLLLTGEVPTEQQVRD 142

Query: 147 VCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFW 206
           +  +   R+ +P  V  L+D  P + +HPM QFS+AV+ L+H S  A+AYA+G  K  +W
Sbjct: 143 LSAEWAARSDLPKFVEELIDHCPTD-LHPMAQFSLAVTALEHTSSFAKAYAKGINKKEYW 201

Query: 207 EYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELN-EFD 265
            Y  ED++ LIA+LP +A+RIY+N F GGK      I+K  D     A  LGF  N +F 
Sbjct: 202 GYTFEDSMDLIAKLPNIASRIYQNVFKGGK---VAAIQKDKDYSFNFANQLGFADNADFV 258

Query: 266 ELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWL 325
           ELMRLYL +H DHEGGNVSAH   LVGSALS P+LS AAGLNGLAGPLHGLANQEVL WL
Sbjct: 259 ELMRLYLTIHTDHEGGNVSAHTTHLVGSALSSPFLSLAAGLNGLAGPLHGLANQEVLNWL 318

Query: 326 LQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHD 385
            + K+ +G+  ++ + + +  W TL  G V+PG+GHAVLR+TDPRY AQR FA + +P+D
Sbjct: 319 TEFKKSVGD-DLSDKAITDYLWSTLNAGRVVPGYGHAVLRKTDPRYMAQRTFAQEKMPND 377

Query: 386 EMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALG 445
            MF+LVS++Y++ P VL E GK KNP+PNVD HSG+LL+YYGL E+N+YTVLFGVSRA+G
Sbjct: 378 PMFKLVSQVYKIAPGVLTEHGKTKNPYPNVDAHSGVLLQYYGLTEANYYTVLFGVSRAIG 437

Query: 446 TLSSLVWDRALGLPIERPKSVTT-QW 470
            L  L+ DRALG PIERPKS +T +W
Sbjct: 438 VLPQLIIDRALGAPIERPKSFSTDKW 463


sp|P20115|CISY_ARATH Citrate synthase, mitochondrial precursor
ref|NP_850415.1| citrate synthase, mitochondrial, putative [Arabidopsis thaliana]
pir||T02390 citrate (si)-synthase (EC 4.1.3.7) F4I1.16 - Arabidopsis thaliana
(474 aa)

Score: 496 bits (1276), Expect: 8.72313e-139
Length: 452, Idn/Pos/Gap = 256/321/8 (56%/71%/1%)

Query:  30 AVRALSTSSATSL--QEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAM  87
           +VR +   S+T L  +  ++  I   + ++ +++   G+  L   TV+   GGMR +  +
Sbjct:  27 SVRWIQMQSSTDLDLKSQLQELIPEQQDRLKKLKSEHGKVQLGNITVDMVIGGMRGMTGL  86

Query:  88 VYETSLLDPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESV 147
           ++ETSLLDP+EGIRFRG SIPECQ++LP A+ SG +PLPEGLLWLLLTG++P++ QVE++
Sbjct:  87 LWETSLLDPEEGIRFRGLSIPECQKVLPTAQ-SGAEPLPEGLLWLLLTGKVPSKEQVEAL 145

Query: 148 CQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWE 207
            +DL  RAAVP  V   +D LP    HPMTQF+  V  LQ +S+  +AY  G  KS FWE
Sbjct: 146 SKDLANRAAVPDYVYNAIDALP-STAHPMTQFASGVMALQVQSEFQKAYENGIHKSKFWE 204

Query: 208 YCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDEL 267
              ED L LIAR+P VAA +YR  +  G  +P++K     D G   +  LGF+  +  EL
Sbjct: 205 PTYEDCLNLIARVPVVAAYVYRRMYKNGDSIPSDKSL---DYGANFSHMLGFDDEKVKEL 261

Query: 268 MRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQ 327
           MRLY+ +H+DHEGGNVSAH   LVGSALSDPYLSFAA LNGLAGPLHGLANQEVL W+  
Sbjct: 262 MRLYITIHSDHEGGNVSAHTGHLVGSALSDPYLSFAAALNGLAGPLHGLANQEVLLWIKS 321

Query: 328 MKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEM 387
           + E+ G   ++ E L+E  W+TL  G VIPG+GH VLR TDPRY  QREFALKHLP D +
Sbjct: 322 VVEECG-EDISKEQLKEYVWKTLNSGKVIPGYGHGVLRNTDPRYVCQREFALKHLPDDPL 380

Query: 388 FQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTL 447
           FQLVSKLYEVVP VL E GKVKNPWPNVD HSG+LL +YGL E+ +YTVLFGVSR+LG  
Sbjct: 381 FQLVSKLYEVVPPVLTELGKVKNPWPNVDAHSGVLLNHYGLTEARYYTVLFGVSRSLGIC 440

Query: 448 SSLVWDRALGLPIERPKSVTTQWIREHFEKRS 479
           S L+WDRALGL +ERPKSVT  W+  H +K S
Sbjct: 441 SQLIWDRALGLALERPKSVTMDWLEAHCKKAS 472


dbj|BAA19410.1| citrate synthase [Candida tropicalis]
sp|P79024|CISY_CANTR Citrate synthase, mitochondrial precursor
(467 aa)

Score: 495 bits (1274), Expect: 1.53844e-138
Length: 444, Idn/Pos/Gap = 250/326/9 (56%/73%/2%)

Query:  28 KRAVRALSTSSATSLQEAVRSKIEPMRAQ-VHEVRERFGEEVLDACTVNQAYGGMRSLKA  86
           K +VR  +T+  T  Q     +I P +A+ V ++++ +G+ V+    + QAYGGMR +K 
Sbjct:  19 KNSVRTYATAEPTLKQRL--EEILPAKAEEVKQLKKDYGKTVIGEVLLEQAYGGMRGIKG  76

Query:  87 MVYETSLLDPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVES 146
           +V+E S+LDP EGIRFRG +IP+ Q+ LP+A P GE+PLPE L WLLLTGE+PTE+Q  +
Sbjct:  77 LVWEGSVLDPIEGIRFRGRTIPDIQKELPKA-PGGEEPLPEALFWLLLTGEVPTEAQTRA 135

Query: 147 VCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFW 206
           + ++   R+A+P  V  L+D  P   +HPM QFS+AV+ L+ ES+ A+AYA+G  KS +W
Sbjct: 136 LSEEFAARSALPKHVEELIDRSP-SHLHPMAQFSIAVTALESESQFAKAYAKGVHKSEYW 194

Query: 207 EYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGF-ELNEFD 265
           +Y  ED++ L+A+LP +AA+IYRN FH GK +PA+ I+   D G  LA  LGF E  EF 
Sbjct: 195 KYTYEDSIELLAKLPTIAAKIYRNVFHDGK-LPAQ-IDSKLDYGANLASLLGFGENKEFL 252

Query: 266 ELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWL 325
           ELMRLYL +H+DHEGGNVSAH   LVGSALS P+LS AAGLNGLAGPLHG ANQEVL WL
Sbjct: 253 ELMRLYLTIHSDHEGGNVSAHTTHLVGSALSSPFLSLAAGLNGLAGPLHGRANQEVLEWL 312

Query: 326 LQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHD 385
            +++E+L N   + E + +  W+TL  G V PG+GHAVLR+TDPRYTAQREFALKH+P  
Sbjct: 313 FKLREEL-NGDYSKEAIEKYLWDTLNAGRVGPGYGHAVLRKTDPRYTAQREFALKHMPDY 371

Query: 386 EMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALG 445
           E+F+LVS +YEV P V ++ G  KNPWPNV  HSG+LL+YYGL E +FYTVLFGVSRA G
Sbjct: 372 ELFKLVSNIYEVAPGVFDQHGMTKNPWPNVGSHSGVLLQYYGLTEESFYTVLFGVSRAFG 431

Query: 446 TLSSLVWDRALGLPIERPKSVTTQ 469
            L  L+ DR LG+PIERPKS +T+
Sbjct: 432 VLPQLILDRGLGMPIERPKSFSTE 455


pir||S41563 citrate (si)-synthase (EC 4.1.3.7), mitochondrial - Neurospora crassa
gb|AAA16630.1| mitochondrial citrate synthase
(469 aa)

Score: 494 bits (1272), Expect: 2.41411e-138
Length: 470, Idn/Pos/Gap = 249/327/15 (52%/69%/3%)

Query:   7 VLALGRRDLRRAEKSWPSDVWKRAVRALSTSSAT---SLQEAVRSKIEPMRAQVHEVRER  63
           V+ LG   LR +           A R  S+ + T      E +   IE ++A    +R+ 
Sbjct:   4 VMRLGSAALRSSIHLTSRQTAFTAARCYSSKTQTLKERFAELLPENIEKIKA----LRKE  59

Query:  64 FGEEVLDACTVNQAYGGMRSLKAMVYETSLLDPQEGIRFRGFSIPECQRLLPRAKPSGEQ 123
            G +V+D  T++Q YGG R +K +V+E S+LD +EGIRFRG +IPECQ LLP+A P G++
Sbjct:  60 HGSKVVDKVTLDQVYGGARGIKCLVWEGSVLDAEEGIRFRGKTIPECQELLPKA-PGGKE 118

Query: 124 PLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAV 183
           PLPEGL WLLLTGE+P+E QV  +  +   R+ VP  +  L+D  P + +HPM Q S+AV
Sbjct: 119 PLPEGLFWLLLTGEVPSEQQVRDLSAEWAARSDVPKFIEELIDRCPSD-LHPMAQLSLAV 177

Query: 184 SLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKI 243
           + L+H S  A AYA+G  K  +W Y  ED++ LIA+LP +AARIY+N F GGK      +
Sbjct: 178 TALEHTSSFARAYAKGINKKEYWGYTFEDSMDLIAKLPTIAARIYQNVFKGGK---VAAV 234

Query: 244 EKVDDMGMRLARSLGFELN-EFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSF 302
           +K  D     A  LGF  N +F EL+RLYL +H DHEGGNVSAH   LVGSALS P+LS 
Sbjct: 235 QKDKDYSFNFANQLGFGDNKDFVELLRLYLTIHTDHEGGNVSAHTTHLVGSALSSPFLSV 294

Query: 303 AAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHA 362
           AAGLNGLAGPLHGLANQEVL WL +MK+ +G+  ++ E + +  W+TL  G V+PG+ HA
Sbjct: 295 AAGLNGLAGPLHGLANQEVLNWLTEMKKVIGD-DLSDEAITKYLWDTLNAGRVVPGYAHA 353

Query: 363 VLRRTDPRYTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGIL 422
           VLR+TDPRY+AQR+FA +HLP D MFQLVS++Y++ P+VL E GK KNP+PNVD HSG+L
Sbjct: 354 VLRKTDPRYSAQRKFAQEHLPEDPMFQLVSQVYKIAPKVLTEHGKTKNPYPNVDAHSGVL 413

Query: 423 LRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLPIERPKSVTT-QWI 471
           L++YGL E+N+YTVLFGVSRA+G L  L+ DRA+G PIERPKS +T +WI
Sbjct: 414 LQHYGLTEANYYTVLFGVSRAIGVLPQLIIDRAVGAPIERPKSYSTDKWI 463


gb|AAG28777.1| citrate synthase [Oryza sativa]
(472 aa)

Score: 494 bits (1272), Expect: 2.53804e-138
Length: 450, Idn/Pos/Gap = 255/323/8 (56%/71%/1%)

Query:  30 AVRALSTSSATSL--QEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAM  87
            VR L   SA+ L  +  ++  I   + ++ +++   G+  L   TV+   GGMR +  M
Sbjct:  26 GVRWLQMQSASDLDLKSQLQELIPEQQDRLKKLKSEHGKVQLGNITVDMVLGGMRGMTGM  85

Query:  88 VYETSLLDPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESV 147
           ++ETSLLDP EGIRFRG SIPECQ++LP A   GE PLPEGLLWLLLTG++PT+ QV+++
Sbjct:  86 LWETSLLDPDEGIRFRGLSIPECQKVLPTAVKDGE-PLPEGLLWLLLTGKVPTKEQVDAL 144

Query: 148 CQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWE 207
            ++L  R++VP  V + +D LP    HPMTQF+  V  LQ ES+  +AY +G  KS FWE
Sbjct: 145 SKELASRSSVPGHVYKAIDALP-VTAHPMTQFTTGVMALQVESEFQKAYDKGMSKSKFWE 203

Query: 208 YCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDEL 267
              ED L LIARLPAVA+ +YR  F GGK + A+      D     +  LGF+  +  EL
Sbjct: 204 PTYEDCLNLIARLPAVASYVYRRIFKGGKTIAADN---ALDYAANFSHMLGFDDPKMLEL 260

Query: 268 MRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQ 327
           MRLY+ +H DHEGGNVSAH   LVGSALSDPYLSFAA LNGLAGPLHGLANQEVL W+  
Sbjct: 261 MRLYITIHTDHEGGNVSAHTGHLVGSALSDPYLSFAAALNGLAGPLHGLANQEVLLWIKS 320

Query: 328 MKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEM 387
           +  + G+  +TT+ L+E  W+TL+ G V+PGFGH VLR+TDPRYT QREFALK+LP D +
Sbjct: 321 VIGETGS-DVTTDQLKEYVWKTLKSGKVVPGFGHGVLRKTDPRYTCQREFALKYLPEDPL 379

Query: 388 FQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTL 447
           FQLVSKLYEVVP +L E GKVKNPWPNVD HSG+LL ++GL E+ +YTVLFGVSR++G  
Sbjct: 380 FQLVSKLYEVVPPILTELGKVKNPWPNVDAHSGVLLNHFGLSEARYYTVLFGVSRSIGIG 439

Query: 448 SSLVWDRALGLPIERPKSVTTQWIREHFEK 477
           S L+WDRALGLP+ERPKSVT +W+  H +K
Sbjct: 440 SQLIWDRALGLPLERPKSVTMEWLENHCKK 469


gb|EAA56847.1| hypothetical protein MG07202.4 [Magnaporthe grisea 70-15]
ref|XP_367277.1| hypothetical protein MG07202.4 [Magnaporthe grisea 70-15]
(473 aa)

Score: 493 bits (1269), Expect: 4.86568e-138
Length: 445, Idn/Pos/Gap = 240/322/12 (53%/72%/2%)

Query:  29 RAVRALSTSSATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMV  88
           R   A + +      E +  KIE    ++  +R+  G +V+D  T++Q YGG R +K +V
Sbjct:  31 RCYSAKTQTLKERFAELLPEKIE----EIKSLRKEHGSKVIDKVTLDQVYGGARGIKCLV  86

Query:  89 YETSLLDPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVC 148
           +E S+LD +EGIRFRG +IPECQ LLP+A P G++PLPEGL WLLLTGE+P+E+QV ++ 
Sbjct:  87 WEGSVLDSEEGIRFRGKTIPECQELLPKA-PGGKEPLPEGLFWLLLTGEVPSEAQVRALS 145

Query: 149 QDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEY 208
            +   R+ +P  V  L+D  P++ +HPM QFS+A++ L+  S  A+AYA+G  K  +W Y
Sbjct: 146 AEWAARSDLPKFVEELIDRCPND-LHPMAQFSMAITALEQTSSFAKAYAKGINKKEYWGY 204

Query: 209 CLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELN-EFDEL 267
             ED++ LIA+LP +AARIY+N F GGK  P   ++K  D     A  LGF  N +F EL
Sbjct: 205 TFEDSMDLIAKLPTIAARIYQNVFKGGKVAP---VQKDKDYSFNFANQLGFGNNSDFVEL 261

Query: 268 MRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQ 327
           +RLYL +H DHEGGNVSAH   LVGSALS P+LS AAG+NGLAGPLHGLANQEVL WL +
Sbjct: 262 LRLYLTIHTDHEGGNVSAHTTHLVGSALSSPFLSLAAGMNGLAGPLHGLANQEVLNWLTE 321

Query: 328 MKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEM 387
           MK+ +G+  ++ +++ +  W TL  G V+PG+GHAVLR+TDPRYTAQR FA + +P+D M
Sbjct: 322 MKKSVGD-DLSDKSITDYLWSTLNSGRVVPGYGHAVLRKTDPRYTAQRVFAQEKMPNDPM 380

Query: 388 FQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTL 447
           F+LVS++Y++ P VL E GK KNP+PNVD HSG+LL+YYGL E+N+YTVLFGVSRA+G L
Sbjct: 381 FKLVSQVYKIAPGVLTEHGKTKNPFPNVDAHSGVLLQYYGLTEANYYTVLFGVSRAIGVL 440

Query: 448 SSLVWDRALGLPIERPKSVTTQ-WI 471
             L+ DRA+G PIERPKS +T+ WI
Sbjct: 441 PQLIIDRAVGAPIERPKSFSTEKWI 465


gb|AAR88248.1| mitochondrial citrate synthase precursor [Citrus junos]
(464 aa)

Score: 493 bits (1269), Expect: 5.94444e-138
Length: 469, Idn/Pos/Gap = 260/330/12 (55%/70%/2%)

Query:   5 RFVLALGRRDLRRAEKSWPSDVWKRAVRALS--TSSATSLQEAVRSKIEPMRAQVHEVRE  62
           R V AL R   R  ++S  S+    +VR L   +SS   L   ++  I   + ++ +V+ 
Sbjct:   5 RSVTALSRLRSRVGQQSNLSN----SVRWLQMQSSSDLDLHSQLKEMIPEQQERLKKVKS  60

Query:  63 RFGEEVLDACTVNQAYGGMRSLKAMVYETSLLDPQEGIRFRGFSIPECQRLLPRAKPSGE 122
             G+  L   TV+   GGMR +  +++ETSLLDP EGIRFRG SIPECQ+LLP AKP GE
Sbjct:  61 ELGKAQLGNITVDMVIGGMRGMTGLLWETSLLDPDEGIRFRGLSIPECQKLLPAAKPDGE 120

Query: 123 QPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVA 182
            PLPEGLLWLLLTG++P++ QV+ + ++L+ RA VP  V + +D LP    HPMTQF+  
Sbjct: 121 -PLPEGLLWLLLTGKVPSKEQVDGLSKELRDRATVPDYVYKAIDALP-VTAHPMTQFASG 178

Query: 183 VSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEK 242
           V  LQ +S+  EAY +G  KS +WE   ED+L LIAR+P VAA +Y+  +  GK +P + 
Sbjct: 179 VMALQVQSEFQEAYEKGIHKSKYWEPTYEDSLNLIARVPVVAAYVYQRIYKDGKIIPKDD 238

Query: 243 IEKVDDMGMRLARSLGFELNEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSF 302
                D G   +  LGF+  +  ELMRLY+ +H+DHEGGNVSAH   LV SALSDPYLSF
Sbjct: 239 SL---DYGGNFSHMLGFDDPKMLELMRLYVTIHSDHEGGNVSAHTGHLVASALSDPYLSF 295

Query: 303 AAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHA 362
           AA LNGLAGPLHGLANQEVL W+  + ++ G   +TTE L++  W+TL  G V+PGFGH 
Sbjct: 296 AAALNGLAGPLHGLANQEVLLWIKSVVDECGEN-VTTEQLKDYVWKTLNSGKVVPGFGHG 354

Query: 363 VLRRTDPRYTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGIL 422
           VLR+TDPRYT QREFALKHLP D +FQLVSKL+EVVP +L + GKVKNPWPNVD HSG+L
Sbjct: 355 VLRKTDPRYTCQREFALKHLPDDPLFQLVSKLFEVVPPILTKLGKVKNPWPNVDAHSGVL 414

Query: 423 LRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLPIERPKSVTTQWI 471
           L ++GL E+ +YTVLFGVSR+LG  S L+WDRALGLP+ERPKSVT  WI
Sbjct: 415 LNHFGLAEARYYTVLFGVSRSLGICSQLIWDRALGLPLERPKSVTLDWI 463


ref|XP_464443.1| citrate synthase [Oryza sativa (japonica cultivar-group)]
dbj|BAD15405.1| citrate synthase [Oryza sativa (japonica cultivar-group)]
(472 aa)

Score: 493 bits (1268), Expect: 7.76367e-138
Length: 450, Idn/Pos/Gap = 255/322/8 (56%/71%/1%)

Query:  30 AVRALSTSSATSL--QEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAM  87
            VR L   SA+ L  +  ++  I   + ++ +++   G+  L   TV+   GGMR +  M
Sbjct:  26 GVRWLQMQSASDLDLKSQLQELIPEQQDRLKKLKSEHGKVQLGNITVDMVLGGMRGMTGM  85

Query:  88 VYETSLLDPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESV 147
           ++ETSLLDP EGIRFRG SIPECQ++LP A   GE PLPEGLLWLLLTG++PT+ QV+++
Sbjct:  86 LWETSLLDPDEGIRFRGLSIPECQKVLPTAVKDGE-PLPEGLLWLLLTGKVPTKEQVDAL 144

Query: 148 CQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWE 207
            ++L  R++VP  V   +D LP    HPMTQF+  V  LQ ES+  +AY +G  KS FWE
Sbjct: 145 SKELASRSSVPGHVYEAIDALP-VTAHPMTQFTTGVMALQVESEFQKAYDKGMSKSKFWE 203

Query: 208 YCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDEL 267
              ED L LIARLPAVA+ +YR  F GGK + A+      D     +  LGF+  +  EL
Sbjct: 204 PTYEDCLNLIARLPAVASYVYRRIFKGGKTIAADN---ALDYAANFSHMLGFDDPKMLEL 260

Query: 268 MRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQ 327
           MRLY+ +H DHEGGNVSAH   LVGSALSDPYLSFAA LNGLAGPLHGLANQEVL W+  
Sbjct: 261 MRLYITIHTDHEGGNVSAHTGHLVGSALSDPYLSFAAALNGLAGPLHGLANQEVLLWIKS 320

Query: 328 MKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEM 387
           +  + G+  +TT+ L+E  W+TL+ G V+PGFGH VLR+TDPRYT QREFALK+LP D +
Sbjct: 321 VIGETGS-DVTTDQLKEYVWKTLKSGKVVPGFGHGVLRKTDPRYTCQREFALKYLPEDPL 379

Query: 388 FQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTL 447
           FQLVSKLYEVVP +L E GKVKNPWPNVD HSG+LL ++GL E+ +YTVLFGVSR++G  
Sbjct: 380 FQLVSKLYEVVPPILTELGKVKNPWPNVDAHSGVLLNHFGLSEARYYTVLFGVSRSIGIG 439

Query: 448 SSLVWDRALGLPIERPKSVTTQWIREHFEK 477
           S L+WDRALGLP+ERPKSVT +W+  H +K
Sbjct: 440 SQLIWDRALGLPLERPKSVTMEWLENHCKK 469


pdb|5CSC|B Chain B, Citrate Synthase (E.C.4.1.3.7)
pdb|5CSC|A Chain A, Citrate Synthase (E.C.4.1.3.7)
(429 aa)

Score: 491 bits (1265), Expect: 1.50084e-137
Length: 432, Idn/Pos/Gap = 244/314/9 (56%/72%/2%)

Query:  37 SSATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYETSLLDP  96
           +S+T+L++ + + I   +A++   R++ G   L   TV+ +YGGMR +K +VYETS+LDP
Sbjct:   1 ASSTNLKDVLAALIPKEQARIKTFRQQHGGTALGQITVDMSYGGMRGMKGLVYETSVLDP  60

Query:  97 QEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAA 156
            EGIRFRGFSIPECQ+ LP  K  G +PLPEGL WLL+TG+IPT +QV  + ++  +RAA
Sbjct:  61 DEGIRFRGFSIPECQKALP--KGGGGEPLPEGLFWLLVTGQIPTGAQVSWLSKEWAKRAA 118

Query: 157 VPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTL 216
           +P  V+ +LD  P   +HPM+Q S A++ L  ES  A AYA+G  ++ +WE   E A+ L
Sbjct: 119 LPSHVVTMLDNFP-TNLHPMSQLSAAITALNSESNFARAYAEGILRTKYWEMVYESAMDL 177

Query: 217 IARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVLHA 276
           IA+LP VAA+IYRN +  G  + A  I+   D        LG+   +F ELMRLYL +H+
Sbjct: 178 IAKLPCVAAKIYRNLYRAGSSIGA--IDSKLDWSHNFTNMLGYTDAQFTELMRLYLTIHS 235

Query: 277 DHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRP 336
           DHEGGNVSAH   LVGSALSDPYLSFAA +NGLAGPLHGLANQEVL WL Q+++  G   
Sbjct: 236 DHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPLHGLANQEVLGWLAQLQKAAG--- 292

Query: 337 MTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSKLYE 396
               +LR+  W TL  G V+PG+GHAVLR+TDPRYT QREFALKHLP D MF+LV++LY+
Sbjct: 293 -ADASLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYTCQREFALKHLPGDPMFKLVAQLYK 351

Query: 397 VVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRAL 456
           +VP VL EQG   NPWPNVD HSG+LL+YYG+ E N+YTVLFGVSRALG L+ L+W RAL
Sbjct: 352 IVPNVLLEQGAAANPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLIWSRAL 411

Query: 457 GLPIERPKSVTT 468
           G P+ERPKS++T
Sbjct: 412 GFPLERPKSMST 423


emb|CAA59010.1| citrate (si)-synthase [Beta vulgaris subsp. vulgaris]
(437 aa)

Score: 491 bits (1265), Expect: 1.67279e-137
Length: 443, Idn/Pos/Gap = 247/321/6 (55%/72%/1%)

Query:  37 SSATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYETSLLDP  96
           SS   L+  ++  I   + ++ ++++ FG   L    V+   GGMR +  +++ETSLLDP
Sbjct:   1 SSNLDLRSELQELIPEQQERLKKIKKEFGSFQLGNINVDMVLGGMRGMTGLLWETSLLDP  60

Query:  97 QEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAA 156
           +EGIRFRGFSIPECQ+LLP A  +G +PLPEGLLWLLLTG++P++ QV+++  DL++RA+
Sbjct:  61 EEGIRFRGFSIPECQKLLP-AASAGAEPLPEGLLWLLLTGKVPSKEQVDALSADLRKRAS 119

Query: 157 VPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTL 216
           +P  V + +D LP    HPMTQF   V  LQ  S+  +AY +G  KS FWE   ED L+L
Sbjct: 120 IPDHVYKTIDALPIT-AHPMTQFCTGVMALQTRSEFQKAYEKGIHKSKFWEPTYEDCLSL 178

Query: 217 IARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVLHA 276
           IA++P VAA +YR  +  G+ +P   ++   D G   A  LGF+  +  ELMRLY+ +H+
Sbjct: 179 IAQVPVVAAYVYRRMYKNGQVIP---LDDSLDYGGNFAHMLGFDSPQMLELMRLYVTIHS 235

Query: 277 DHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRP 336
           DHEGGNVSAH   LVGS LSDPYLSFAA LNGLAGPLHGLANQEVL W+  + ++ G   
Sbjct: 236 DHEGGNVSAHTGHLVGSPLSDPYLSFAAALNGLAGPLHGLANQEVLLWIKSVVDECGEN- 294

Query: 337 MTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSKLYE 396
           ++TE L++  W+TL  G V+PGFG  VLR+TDPRYT QREFALKHLP D  FQLVSKLYE
Sbjct: 295 ISTEQLKDYVWKTLNSGKVVPGFGLGVLRKTDPRYTCQREFALKHLPDDPFFQLVSKLYE 354

Query: 397 VVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRAL 456
           VVP +L E GKVKNPWPNVD HSG+LL +YGL E+ +YTVLFGVSR+LG  S L+WDRAL
Sbjct: 355 VVPPILLELGKVKNPWPNVDAHSGVLLNHYGLTEARYYTVLFGVSRSLGICSQLIWDRAL 414

Query: 457 GLPIERPKSVTTQWIREHFEKRS 479
           GLP+ERPKSVT +W+ +  ++R+
Sbjct: 415 GLPLERPKSVTMEWLEKFCKRRA 437


sp|O80433|CISY_DAUCA Citrate synthase, mitochondrial precursor
dbj|BAA32557.1| citrate synthase [Daucus carota]
(472 aa)

Score: 490 bits (1262), Expect: 3.75782e-137
Length: 451, Idn/Pos/Gap = 249/319/6 (55%/70%/1%)

Query:  29 RAVRALSTSSATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMV  88
           R  +  +++S   L+  ++  I   + ++ +++   G+  L   TV+   GGMR +  ++
Sbjct:  28 RWFQVQTSASDLDLRSQLKELIPEQQERIKKLKAEHGKVQLGNITVDMVLGGMRGMTGLL  87

Query:  89 YETSLLDPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVC 148
           +ETSLLDP+EGIRFRG SIPECQ+LLP AKP GE PLPEGLLWLLLTG++PT+ QV+++ 
Sbjct:  88 WETSLLDPEEGIRFRGLSIPECQKLLPGAKPGGE-PLPEGLLWLLLTGKVPTKEQVDALS 146

Query: 149 QDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEY 208
            +L+ RAAVP  V + +D LP    HPMTQF+  V  LQ +S+  +AY +G  K+ +WE 
Sbjct: 147 AELRSRAAVPEHVYKTIDALP-VTAHPMTQFATGVMALQVQSEFQKAYEKGIHKTKYWEP 205

Query: 209 CLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELM 268
             ED++TLIA+LP VAA IYR  +  G+ +  +      D G   A  LG++     ELM
Sbjct: 206 TYEDSITLIAQLPVVAAYIYRRMYKNGQSISTDDSL---DYGANFAHMLGYDSPSMQELM 262

Query: 269 RLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQM 328
           RLY+ +H DHEGGNVSAH   LV SALSDPYLSFAA LNGLAGPLHGLANQEVL W+  +
Sbjct: 263 RLYVTIHTDHEGGNVSAHTGHLVASALSDPYLSFAAALNGLAGPLHGLANQEVLLWIKSV 322

Query: 329 KEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMF 388
             + G   +T E L++  W+TL  G V+PG+GH VLR TDPRY  QREFALKHLP D +F
Sbjct: 323 VSECGEN-VTKEQLKDYIWKTLNSGKVVPGYGHGVLRNTDPRYICQREFALKHLPDDPLF 381

Query: 389 QLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLS 448
           QLVS L+EVVP +L E GKVKNPWPNVD HSG+LL +YGL E+ +YTVLFGVSRA+G  S
Sbjct: 382 QLVSNLFEVVPPILTELGKVKNPWPNVDAHSGVLLNHYGLTEARYYTVLFGVSRAIGICS 441

Query: 449 SLVWDRALGLPIERPKSVTTQWIREHFEKRS 479
            LVWDRALGLP+ERPKSVT +W+  H +K S
Sbjct: 442 QLVWDRALGLPLERPKSVTMEWLENHCKKSS 472


emb|CAG89621.1| unnamed protein product [Debaryomyces hansenii CBS767]
ref|XP_461233.1| unnamed protein product [Debaryomyces hansenii]
(408 aa)

Score: 489 bits (1259), Expect: 7.32534e-137
Length: 403, Idn/Pos/Gap = 242/299/7 (60%/74%/1%)

Query:  68 VLDACTVNQAYGGMRSLKAMVYETSLLDPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPE 127
           V+    + QAYGGMR +K +V+E S+LDP EGIRFRG +IP+ Q  LP+A P G +PLPE
Sbjct:   1 VIGEVLLEQAYGGMRGIKGLVWEGSVLDPIEGIRFRGRTIPDIQEQLPKA-PGGSEPLPE  59

Query: 128 GLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQ 187
            L WLLLTGE+P+ +Q ++  Q+L  R+A+P  V  L+D  P   +HPM QFS+AV+ L+
Sbjct:  60 ALFWLLLTGEVPSVAQTKAFSQELAARSALPKHVEELIDRSP-SHLHPMAQFSIAVTALE 118

Query: 188 HESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVD 247
            ES+ A+AYA+G  KS +W+Y  ED++ L+A+LP +AARIYRN FH G+      I+   
Sbjct: 119 SESQFAKAYAKGVNKSEYWDYTYEDSIDLLAKLPNIAARIYRNVFHDGR---LGAIDSSL 175

Query: 248 DMGMRLARSLGF-ELNEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGL 306
           D    LA  LGF E  EF ELMRLYL +H+DHEGGNVSAH   LVGSALS P+LS AAGL
Sbjct: 176 DYSANLANLLGFGENKEFLELMRLYLTIHSDHEGGNVSAHTTHLVGSALSSPFLSLAAGL 235

Query: 307 NGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRR 366
           NGLAGPLHG ANQEVL WL +M+ +L N   + EN+ +  WETL  G V+PG+GHAVLR+
Sbjct: 236 NGLAGPLHGRANQEVLEWLFKMRGEL-NGDYSKENIEKYLWETLNAGRVVPGYGHAVLRK 294

Query: 367 TDPRYTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYY 426
           TDPRYTAQREFALKH+P  E+FQLVS +YEV P VL + GK KNPWPNVD HSG+LL+YY
Sbjct: 295 TDPRYTAQREFALKHMPDYELFQLVSNVYEVAPGVLTKHGKTKNPWPNVDSHSGVLLQYY 354

Query: 427 GLVESNFYTVLFGVSRALGTLSSLVWDRALGLPIERPKSVTTQ 469
           GL E +FYTVLFGVSRA G L  L+ DR LGLPIERPKS +T+
Sbjct: 355 GLTEESFYTVLFGVSRAFGVLPQLILDRGLGLPIERPKSFSTE 397


gb|AAL11504.1| citrate synthase [Prunus persica]
(473 aa)

Score: 489 bits (1258), Expect: 9.89188e-137
Length: 479, Idn/Pos/Gap = 256/339/12 (53%/70%/2%)

Query:   5 RFVLALGRRDLRRAEKSWPSDVWKRAVRALSTSSATSL--QEAVRSKIEPMRAQVHEVRE  62
           R V AL +   R  ++S   D    +VR L T ++T L  +  ++  I   + ++ +++ 
Sbjct:   5 RSVNALSKLRSRLGQQSNLRD----SVRWLQTQTSTDLDLRSQLKELIPEQQERLKKIKA  60

Query:  63 RFGEEVLDACTVNQAYGGMRSLKAMVYETSLLDPQEGIRFRGFSIPECQRLLPRAKPSGE 122
            +G+  L   TV+   GGMR +  +++ETSLLDP EGIRFRG SIPECQ++LP AKP GE
Sbjct:  61 EYGKVQLGNITVDMVLGGMRGMTGLLWETSLLDPDEGIRFRGLSIPECQKVLPGAKPGGE 120

Query: 123 QPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVA 182
            PLPEGLLWLLLTG++P++ QV+++  +L+ RAAVP  V + +D LP    HPMTQF+  
Sbjct: 121 -PLPEGLLWLLLTGKVPSKEQVDALSXELRSRAAVPDYVYKAIDALPIT-AHPMTQFTTG 178

Query: 183 VSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEK 242
           V  LQ +S+  +AY  G  KS +WE   ED+L+LIA+LP VA+ +Y+  F  GK +P   
Sbjct: 179 VMALQVQSEFQKAYDXGIYKSKYWEPTFEDSLSLIAQLPVVASYVYQRIFKDGKVIP--- 235

Query: 243 IEKVDDMGMRLARSLGFELNEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSF 302
           ++   D G   +   GF+  +  ELMRLY+ +H+DHEGGNVSAH   LV SALSDPYLSF
Sbjct: 236 VDDSLDYGANFSHLWGFDDPKMHELMRLYVTIHSDHEGGNVSAHTGHLVASALSDPYLSF 295

Query: 303 AAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHA 362
           AA LNGLAGPLHGLANQEVL W+  + +++G   +TTE L++  W+TL  G V+PGFGH 
Sbjct: 296 AAALNGLAGPLHGLANQEVLLWIKSVVDEVGEN-VTTEQLKDYVWKTLNSGKVVPGFGHG 354

Query: 363 VLRRTDPRYTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGIL 422
           VLR+TDPRY+ QREFALKHLP D +FQLVSKLYEVVP +L E GKVKNPWPNVD HSG+L
Sbjct: 355 VLRKTDPRYSCQREFALKHLPDDPLFQLVSKLYEVVPPILIELGKVKNPWPNVDAHSGVL 414

Query: 423 LRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLPIERPKSVTTQWIREHFEKRSVS 481
           L ++GL E+ F+TVLFGVSR++G  S L+WDRALGLP+ERPKSVT + +  + +K + S
Sbjct: 415 LNHFGLTEARFFTVLFGVSRSIGIGSQLIWDRALGLPLERPKSVTMESLENYCKKAASS 473


gb|AAA82743.1| citrate synthase precursor
sp|P49298|CISY_CITMA Citrate synthase, mitochondrial precursor
(471 aa)

Score: 488 bits (1256), Expect: 1.64559e-136
Length: 479, Idn/Pos/Gap = 259/331/12 (54%/69%/2%)

Query:   1 MHCARFVLALGRRDLRRAEKSWPSDVWKRAVRALSTSSATSL--QEAVRSKIEPMRAQVH  58
           M   R   AL R   R  ++S  S+    +VR L   S+  L     ++  I   + ++ 
Sbjct:   1 MASLRSATALSRLRSRAGQQSNLSN----SVRWLQMQSSADLDLHSQLKEMIPEQQERLK  56

Query:  59 EVRERFGEEVLDACTVNQAYGGMRSLKAMVYETSLLDPQEGIRFRGFSIPECQRLLPRAK 118
           +V+   G+  L   T++   GGMR +  +++ETSLLDP EGIRFRG SIPECQ+LLP AK
Sbjct:  57 KVKSDLGKAQLGNITIDVVIGGMRGMTGLLWETSLLDPDEGIRFRGLSIPECQKLLPAAK 116

Query: 119 PSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQ 178
           P GE PLPEGLLWLLLTG++P++ QV+ + ++L+ RA VP  V + +D LP    HPMTQ
Sbjct: 117 PDGE-PLPEGLLWLLLTGKVPSKEQVDGLSKELRDRATVPDYVYKAIDALP-VSAHPMTQ 174

Query: 179 FSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHV 238
           F+  V  LQ +S+  EAY +G  KS  WE   ED+L LIAR+P VAA +Y+  +  GK +
Sbjct: 175 FASGVMALQVQSEFQEAYEKGIHKSKSWEPTSEDSLNLIARVPVVAAYVYQRIYKDGKII 234

Query: 239 PAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDP 298
           P +      D G   +  LGF+  +  ELMRLY+ +H+DHEGGNVSAH   LV SALSDP
Sbjct: 235 PKDDSL---DYGGNFSHMLGFDDPKMLELMRLYVTIHSDHEGGNVSAHTGHLVASALSDP 291

Query: 299 YLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPG 358
           YLSF A LNGLAGPLHGLANQEVL W+  + ++ G   +TTE L++  W+TL  G V+PG
Sbjct: 292 YLSFLAALNGLAGPLHGLANQEVLLWIKSVVDECGEN-VTTEQLKDYVWKTLNSGKVVPG 350

Query: 359 FGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQH 418
           FGH VLR+TDPRYT QREFALKHLP D +FQLVSKLYEVVP +L + GKVKNPWPNVD H
Sbjct: 351 FGHGVLRKTDPRYTCQREFALKHLPDDPLFQLVSKLYEVVPPILTKLGKVKNPWPNVDAH 410

Query: 419 SGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLPIERPKSVTTQWIREHFEK 477
           SG+LL ++GL E+ +YTVLFGVSR+LG  S L+WDRALGLP+ERPKSVT  WI ++ +K
Sbjct: 411 SGVLLNHFGLAEARYYTVLFGVSRSLGICSQLIWDRALGLPLERPKSVTLDWIEKNCKK 469


gb|EAK96136.1| hypothetical protein CaO19.4393 [Candida albicans SC5314]
gb|EAK96084.1| hypothetical protein CaO19.11871 [Candida albicans SC5314]
(397 aa)

Score: 483 bits (1243), Expect: 4.86991e-135
Length: 390, Idn/Pos/Gap = 236/299/6 (60%/76%/1%)

Query:  81 MRSLKAMVYETSLLDPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPT 140
           MR +K +V+E S+LDP EGIRFRG +IP+ Q+ LP+A P GE+PLPE L WLLLTGE+PT
Sbjct:   1 MRGIKGLVWEGSVLDPIEGIRFRGRTIPDIQKELPKA-PGGEEPLPEALFWLLLTGEVPT  59

Query: 141 ESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGA 200
           ++Q +++ ++   R+A+P  V  L+D  P   +HPM QFS+AV+ L+ ES+ A+AYA+GA
Sbjct:  60 DAQTKALSEEFAARSALPKHVEELIDRSP-SHLHPMAQFSIAVTALESESQFAQAYAKGA 118

Query: 201 PKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFE 260
            KS +W+Y  ED++ L+A+LP +AA+IYRN FH GK +PA  I+   D G  LA  LGF 
Sbjct: 119 NKSEYWKYTYEDSIDLLAKLPTIAAKIYRNVFHDGK-LPA-AIDSKLDYGANLASLLGFG 176

Query: 261 LN-EFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQ 319
            N EF ELMRLYL +H+DHEGGNVSAH   LVGSALS P+LS AAGLNGLAGPLHG ANQ
Sbjct: 177 DNKEFVELMRLYLTIHSDHEGGNVSAHTTHLVGSALSSPFLSLAAGLNGLAGPLHGRANQ 236

Query: 320 EVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFAL 379
           EVL WL +++E+L N   + E + +  WETL  G V+PG+GHAVLR+TDPRYTAQREFAL
Sbjct: 237 EVLEWLFKLREEL-NGDYSKEAIEKYLWETLNSGRVVPGYGHAVLRKTDPRYTAQREFAL 295

Query: 380 KHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFG 439
           KH+P  E+F+LVS +YEV P VL + GK KNPWPNVD HSG+LL+YYGL E +FYTVLFG
Sbjct: 296 KHMPDYELFKLVSNIYEVAPGVLTKHGKTKNPWPNVDSHSGVLLQYYGLTEQSFYTVLFG 355

Query: 440 VSRALGTLSSLVWDRALGLPIERPKSVTTQ 469
           VSRA G L  L+ DR +G+PIERPKS +T+
Sbjct: 356 VSRAFGVLPQLILDRGIGMPIERPKSFSTE 385


emb|CAA77442.1| citrate synthase [Saccharomyces cerevisiae]
emb|CAA42342.1| citrate (si)-synthase, peroxisomal [Saccharomyces cerevisiae]
gb|AAT92856.1| YCR005C [Saccharomyces cerevisiae]
pir||YKBYC citrate (si)-synthase (EC 4.1.3.7), peroxisomal - yeast  (Saccharomyces cerevisiae)
ref|NP_009931.1| Cit2p [Saccharomyces cerevisiae]
sp|P08679|CISZ_YEAST Citrate synthase, peroxisomal
gb|AAA34497.1| citrate synthase (CIT2)
(460 aa)

Score: 483 bits (1242), Expect: 6.41359e-135
Length: 440, Idn/Pos/Gap = 239/314/8 (54%/71%/1%)

Query:  35 STSSATSLQEAVRSKIEPMRAQ-VHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYETSL  93
           ++S   +L+E   S+I P+ AQ V +  +  G+  +    + Q YGGMR +   V+E S+
Sbjct:  19 NSSQEKTLKERF-SEIYPIHAQDVRQFVKEHGKTKISDVLLEQVYGGMRGIPGSVWEGSV  77

Query:  94 LDPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKR 153
           LDP++GIRFRG +I + Q+ LP+AK S  QPLPE L WLLLTGE+PT++QVE++  DL  
Sbjct:  78 LDPEDGIRFRGRTIADIQKDLPKAKGS-SQPLPEALFWLLLTGEVPTQAQVENLSADLMS 136

Query: 154 RAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDA 213
           R+ +P  V++LLD LP + +HPM QFS+AV+ L+ ESK A+AYAQG  K  +W Y  ED+
Sbjct: 137 RSELPSHVVQLLDNLPKD-LHPMAQFSIAVTALESESKFAKAYAQGISKQDYWSYTFEDS 195

Query: 214 LTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLV 273
           L L+ +LP +AA+IYRN F  GK     +++   D    L   +G +  +F +LMRLYL 
Sbjct: 196 LDLLGKLPVIAAKIYRNVFKDGK---MGEVDPNADYAKNLVNLIGSKDEDFVDLMRLYLT 252

Query: 274 LHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLG 333
           +H+DHEGGNVSAH   LVGSALS PYLS A+GLNGLAGPLHG ANQEVL WL  +KE++ 
Sbjct: 253 IHSDHEGGNVSAHTSHLVGSALSSPYLSLASGLNGLAGPLHGRANQEVLEWLFALKEEV- 311

Query: 334 NRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSK 393
           N   + + + +  W+TL  G VIPG+GHAVLR+TDPRY AQR+FA+ H P  E+F+LVS 
Sbjct: 312 NDDYSKDTIEKYLWDTLNSGRVIPGYGHAVLRKTDPRYMAQRKFAMDHFPDYELFKLVSS 371

Query: 394 LYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWD 453
           +YEV P VL E GK KNPWPNVD HSG+LL+YYGL ES+FYTVLFGVSRA G L+ L+ D
Sbjct: 372 IYEVAPGVLTEHGKTKNPWPNVDAHSGVLLQYYGLKESSFYTVLFGVSRAFGILAQLITD 431

Query: 454 RALGLPIERPKSVTTQWIRE 473
           RA+G  IERPKS +T+  +E
Sbjct: 432 RAIGASIERPKSYSTEKYKE 451


emb|CAA59008.1| citrate synthase [Nicotiana tabacum]
(469 aa)

Score: 478 bits (1231), Expect: 1.30388e-133
Length: 444, Idn/Pos/Gap = 244/316/7 (54%/71%/1%)

Query:  34 LSTSSATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYETSL  93
           + TSS   L+  ++  I   + ++ +++   G+  L   TV+   GGMR +  +++ETSL
Sbjct:  32 VQTSSGLDLRSELQELIPEQQDRLKKLKSEHGKVQLGNITVDMVLGGMRGMTGLLWETSL  91

Query:  94 LDPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKR 153
           LDP EGIRFRG SI ECQ++LP AKP GE PLPEGLLWLLLTG++P++ QV+S+ Q+L+ 
Sbjct:  92 LDPDEGIRFRGLSIYECQKVLPAAKPGGE-PLPEGLLWLLLTGKVPSKEQVDSLSQELRS 150

Query: 154 RAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDA 213
           RA VP  V + +D LP    HPMTQF+  V  LQ +S+  +AY +G  KS  WE   ED+
Sbjct: 151 RATVPDHVYKTIDALP-VTAHPMTQFATGVMALQVQSEFQKAYEKGIHKSKLWEPTYEDS 209

Query: 214 LTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLV 273
           ++LIA++P VAA +YR  +  G  +P +      D G   A  LGF  ++  ELM+LY+ 
Sbjct: 210 MSLIAQVPLVAAYVYRRMYKNGNTIPKDDSL---DYGANFAHMLGFSSSDMHELMKLYVT 266

Query: 274 LHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLG 333
           +H+DHEGGNVSAH   LV SALSDPYLSFAA LNGLAGPLHGLANQEVL W+  + E+ G
Sbjct: 267 IHSDHEGGNVSAHTGHLVASALSDPYLSFAAALNGLAGPLHGLANQEVLLWIKSVVEECG 326

Query: 334 NRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSK 393
              ++ E L++  W+TL+ G V+PGFGH VLR+TDPRYT QREFALKHLP D +FQLV+K
Sbjct: 327 EN-ISKEQLKDYAWKTLKSGKVVPGFGHGVLRKTDPRYTCQREFALKHLPEDPLFQLVAK 385

Query: 394 LYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWD 453
           LYEV  + L+   K+ NPWPNVD HSG+LL YYGL E+ +YTVLFGVSRALG  S L+WD
Sbjct: 386 LYEVFLQFLQNLAKL-NPWPNVDAHSGVLLNYYGLTEARYYTVLFGVSRALGICSQLIWD 444

Query: 454 RALGLPIERPKSVTTQWIREHFEK 477
           RALGLP+ERPKSVT +W+  H +K
Sbjct: 445 RALGLPLERPKSVTMEWLENHCKK 468


emb|CAB75925.1| citrate synthase-like protein [Arabidopsis thaliana]
ref|NP_191569.1| citrate synthase, mitochondrial, putative [Arabidopsis thaliana]
pir||T47834 citrate synthase-like protein - Arabidopsis thaliana
(433 aa)

Score: 469 bits (1207), Expect: 7.84463e-131
Length: 431, Idn/Pos/Gap = 242/307/12 (56%/71%/2%)

Query:  42 LQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYETSLLDPQEGIR 101
           L+  ++  I   + ++ +++   G+  +   TV+   GGMR +  +++ETSLLD  EGIR
Sbjct:   6 LKSQMQEIIPEQQDRLKKLKSEQGKVPVGNITVDMVLGGMRGMTGLLWETSLLDADEGIR  65

Query: 102 FRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEV 161
           FRG SIPECQ++LP A+ SGE+PLPE LLWLLLTG++PT+ Q  ++  +L  RAAVP   
Sbjct:  66 FRGMSIPECQKILPSAE-SGEEPLPESLLWLLLTGKVPTKEQANALSTELAHRAAVPA-- 122

Query: 162 LRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQG-APKSTFWEYCLEDALTLIARL 220
              +D LP    HPMTQF+  V  LQ +S+  +AY QG   KS +WE   EDAL LIAR+
Sbjct: 123 ---IDALP-STAHPMTQFASGVMALQVQSEFQKAYEQGDISKSKYWEPTFEDALNLIARV 178

Query: 221 PAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVLHADHEG 280
           P VA+ +YR  +  G  +P   ++   D G   +  LGF+  +  ELMRLY+ +H+DHEG
Sbjct: 179 PVVASYVYRRMYKDGSIIP---LDDSLDYGANFSHMLGFDSPQMKELMRLYVTIHSDHEG 235

Query: 281 GNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTE 340
           GNVSAHA  LVGSALSDPYLSFAA LNGLAGPLHGLANQEVL W+  + E+ G   ++ E
Sbjct: 236 GNVSAHAGHLVGSALSDPYLSFAAALNGLAGPLHGLANQEVLLWIKLVVEECG-ESISKE 294

Query: 341 NLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSKLYEVVPR 400
            L++  W+TL  G V+PG+GH VLR+TDPRY  QREFALKHLP D +FQLVSKLYEVVP 
Sbjct: 295 QLKDYVWKTLNSGKVVPGYGHGVLRKTDPRYICQREFALKHLPDDPLFQLVSKLYEVVPP 354

Query: 401 VLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLPI 460
           +L E GKVKNPWPNVD HSG+LL YYGL E+ +YTVLFGVSR+LG  S L+WDRALGLP+
Sbjct: 355 ILTELGKVKNPWPNVDAHSGVLLNYYGLTEARYYTVLFGVSRSLGICSQLIWDRALGLPL 414

Query: 461 ERPKSVTTQWI 471
           ERPKSV   W+
Sbjct: 415 ERPKSVNMDWL 425


sp|P83372|CISY_FRAAN Citrate synthase, mitochondrial precursor
(469 aa)

Score: 456 bits (1173), Expect: 6.26957e-127
Length: 464, Idn/Pos/Gap = 242/322/25 (52%/69%/5%)

Query:  28 KRAVRALST--SSATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLK  85
           + +VR L T  SS   L   ++  I   + ++ ++++  G+  L   TV+   GGMR + 
Sbjct:  21 RDSVRCLQTQASSDLDLHSQLKELIPEQQERLKKLKKEHGKVQLGTITVDMVIGGMRGMT  80

Query:  86 AMVYETSLLDPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVE 145
            +++ETSLLDP EGIRFRG SIPECQ++LP A P GE PLPEGLLWLLLTG++P+ S+  
Sbjct:  81 GLLWETSLLDPDEGIRFRGLSIPECQKVLPGATPGGE-PLPEGLLWLLLTGKVPSRSKNM 139

Query: 146 SVCQDLKRRAAVP--------PEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYA 197
               +      VP        P +L LL+ +P      MTQF+  V  LQ +S+  +AY 
Sbjct: 140 HYPVN---NGVVPKFQIMCSRPLMLCLLEHIP------MTQFTTGVMALQVQSEFQKAYD 190

Query: 198 QGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSL 257
           +G PKS +WE   ED+L+LIA+LP VA+ +YR  + GG+ +P   ++   D G   +  L
Sbjct: 191 KGIPKSRYWEPTYEDSLSLIAQLPVVASYVYRRIYKGGRMIP---VDDSLDYGGNFSHLL 247

Query: 258 GFELNEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLA 317
           GF+ ++  ELMRLY+ +H+DHEGGNVSAH   LV SALSDP+LSFAA LNGLAGPLHGLA
Sbjct: 248 GFDDHKMQELMRLYVTIHSDHEGGNVSAHTGHLVASALSDPFLSFAAALNGLAGPLHGLA 307

Query: 318 NQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREF 377
           NQEVL W+  + ++ G   +T + L++  W+TL  G V+PGFGH VLR+TDPRYT QREF
Sbjct: 308 NQEVLLWIKSVVDECGEN-ITKDQLKDYVWKTLNSGKVVPGFGHGVLRKTDPRYTCQREF 366

Query: 378 ALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVL 437
           ALKHLP D +F+LVSKLY+VVP +L E GKVKNPWPNVD HSG+LL ++GL E+ ++TVL
Sbjct: 367 ALKHLPDDPLFRLVSKLYDVVPPILTELGKVKNPWPNVDAHSGVLLNHFGLTEARYFTVL 426

Query: 438 FGVSRALGTLSSLVWDRALGLPIERPKSVTTQWIREHFEKRSVS 481
           FGVSR++G  S L+WDRALGLP+ERPKSVT + + E F K++ S
Sbjct: 427 FGVSRSIGIGSQLIWDRALGLPLERPKSVTMESL-ESFCKKAAS 469


gb|AAV27294.1| citrate synthase [Oryza sativa (japonica cultivar-group)]
(474 aa)

Score: 449 bits (1154), Expect: 1.19264e-124
Length: 452, Idn/Pos/Gap = 242/312/10 (53%/69%/2%)

Query:  30 AVRALSTSSATSL--QEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAM  87
            VR L   SA+ L  +  ++  I   + ++ +++   G+  L   TV+   GGMR +  M
Sbjct:  26 GVRWLQMQSASDLDLKSQLQELIPEQQDRLKKLKSEHGKVQLGNITVDMVLGGMRGMTGM  85

Query:  88 VYETSLLDPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESV 147
           ++ETSLLDP EGIRFRG SIPE Q++LP A   GE PLPEGLLWLLLTG++PT+ QV+++
Sbjct:  86 LWETSLLDPDEGIRFRGLSIPERQKVLPTAVKDGE-PLPEGLLWLLLTGKVPTKEQVDAL 144

Query: 148 CQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEA-YAQGAPKSTFW 206
            ++L  R++VP  V   +D LP    HPMTQF+  V  LQ ES+  ++   +G  KS FW
Sbjct: 145 SKELASRSSVPGHVYEAIDALP-VTAHPMTQFTTGVMALQVESEFQKSPMTKGMSKSKFW 203

Query: 207 EYCLEDALTL-IARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFD 265
           E   E  L    +   +  + +YR  F GGK + A+      D     +  LGF+  +  
Sbjct: 204 EPTYERLLKFDSSPSSSGLSYVYRRIFKGGKTIAADN---ALDYAANFSHMLGFDDPKML 260

Query: 266 ELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWL 325
           ELMRLY+ +H DHEGGNVSAH   LVGSALSDPYLSFAA LNGLAGPLHGLANQEVL W+
Sbjct: 261 ELMRLYITIHTDHEGGNVSAHTGHLVGSALSDPYLSFAAALNGLAGPLHGLANQEVLLWI 320

Query: 326 LQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHD 385
             +  + G+  +TT+ L+E  W+TL+ G V+PGFGH VLR+TDPRYT QREFALK+LP D
Sbjct: 321 KSVIGETGS-DVTTDQLKEYVWKTLKGGKVVPGFGHGVLRKTDPRYTCQREFALKYLPED 379

Query: 386 EMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALG 445
            +FQLVSKLYEVVP +L E GKVKNPWPNVD HSG+LL ++GL E+ +YTVLFGVSR++G
Sbjct: 380 PLFQLVSKLYEVVPPILTELGKVKNPWPNVDAHSGVLLNHFGLSEARYYTVLFGVSRSIG 439

Query: 446 TLSSLVWDRALGLPIERPKSVTTQWIREHFEK 477
             S L+WDRALGLP+ERPKSVT +W+  H +K
Sbjct: 440 IGSQLIWDRALGLPLERPKSVTMEWLENHCKK 471


emb|CAH03447.1| Citrate synthase, mitochondrial precursor, putative [Paramecium tetraurelia]
ref|YP_054178.1| Citrate synthase, mitochondrial precursor, putative [Paramecium tetraurelia]
(455 aa)

Score: 444 bits (1142), Expect: 3.01204e-123
Length: 447, Idn/Pos/Gap = 221/315/12 (49%/70%/2%)

Query:  38 SATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYETSLLDPQ  97
           S+  L+E +R  I   +A + ++R+++G++ +   TV+QA GGMR++  + Y+ SLLD +
Sbjct:  16 SSNLLKERLRQIIPVKQAILRDIRKQYGQKEICKVTVDQAIGGMRNVFGLFYDISLLDSK  75

Query:  98 EGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAV 157
            GI FR ++IPE Q  L +AK +G +PLPE L WLLLTG+ P++ + + V ++ KRR  +
Sbjct:  76 TGITFRDYNIPEIQEYLQKAK-NGNEPLPEALFWLLLTGDFPSDQEFKFVQEEWKRRGEL 134

Query: 158 PPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQG-APKSTFWEYCLEDALTL 216
             E ++ +  LP +++HPMT  S +V  LQ +S   +AY  G A K  +WEY  EDA+ L
Sbjct: 135 DQETVKFITSLP-KQLHPMTMLSQSVLYLQKDSTFQQAYESGKATKPQYWEYYYEDAMDL 193

Query: 217 IARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFD--ELMRLYLVL 274
           +A+LP VAA IYR+ +  G+ + ++      D     +  +GF  N+FD  EL R+YL +
Sbjct: 194 VAKLPRVAALIYRHKYKNGELINSDSSL---DWAANYSHMMGF--NQFDAYELFRMYLSI 248

Query: 275 HADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGN 334
           HADHEGGNVSAHA  LVGSAL+D YLS++AG+NGLAGPLHGLANQEVL+WL++++EKLG+
Sbjct: 249 HADHEGGNVSAHATHLVGSALADQYLSYSAGINGLAGPLHGLANQEVLKWLIEIREKLGD 308

Query: 335 RPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSKL 394
           + ++ E ++E    T+REG V+PG+GHAVLR TDPRY  Q+ FA + + +D + +LV + 
Sbjct: 309 K-VSNEKIQEYVLNTIREGKVVPGYGHAVLRYTDPRYIHQKNFAERLIKNDPLVELVKQC 367

Query: 395 YEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDR 454
           Y V+P VL+  GK++NPWPNVD HSG+LL +YGL E  +YTV+F VSRALG  ++LVW R
Sbjct: 368 YHVIPPVLKTIGKIQNPWPNVDAHSGVLLNHYGLKEFEYYTVVFAVSRALGCTANLVWAR 427

Query: 455 ALGLPIERPKSVTTQWIREHF-EKRSV 480
           A GLPIERP S+T +WI E F E +SV
Sbjct: 428 AFGLPIERPGSITMRWIEEKFGENQSV 454


emb|CAA52976.1| ethanolamine ammonia-lyase; mitochondrial citrate-synthase [Solanum tuberosum]
pir||S44316 citrate (si)-synthase (EC 4.1.3.7), mitochondrial - potato
sp|Q43175|CISY_SOLTU Citrate synthase, mitochondrial precursor
(471 aa)

Score: 440 bits (1132), Expect: 4.03472e-122
Length: 453, Idn/Pos/Gap = 236/307/13 (52%/67%/2%)

Query:  30 AVRALSTSSATSL---QEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKA  86
           +VR L   +++ L    E V+  I   + ++ +++      + +  TV+   GGMR +  
Sbjct:  26 SVRWLQVQTSSGLDLRSELVQELIPEQQDRLKKIKSDMKGSIGN-ITVDMVLGGMRGMTG  84

Query:  87 MVYETSLLDPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVES 146
           ++++   LDP EGIRFRG SIPECQ++LP AKP GE PLPEGLLWLLLTG++P++ QV S
Sbjct:  85 LLWKPHYLDPDEGIRFRGLSIPECQKVLPAAKPGGE-PLPEGLLWLLLTGKVPSKEQVNS 143

Query: 147 VCQDLKRRAAVPPEVL-RLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTF 205
           +   +     +   ++   +D LP    HPMTQF+  V  LQ +S+  +AY +G  KS +
Sbjct: 144 IVSGIAESGIISLIIMYTTIDALP-VTAHPMTQFATGVMALQVQSEFQKAYEKGIHKSKY 202

Query: 206 WEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFD 265
           WE   ED++ LIA++P VAA +YR  +  G  +P  K E +D  G   A  LGF  +E  
Sbjct: 203 WEPTYEDSMNLIAQVPLVAAYVYRRMYKNGDTIP--KDESLD-YGANFAHMLGFSSSEMH 259

Query: 266 EL-MRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRW 324
           EL MRLY+ +H+DHEGGNVSAH   LV SALSDPYLSFAA LNGLAGPLHGLANQEVL W
Sbjct: 260 ELLMRLYVTIHSDHEGGNVSAHTGHLVASALSDPYLSFAAALNGLAGPLHGLANQEVLLW 319

Query: 325 LLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPH 384
           +  + E+ G   ++ E L++  W+TL  G V+PGFGH VLR+T PRYT QREFA+KHLP 
Sbjct: 320 IKSVVEECGEN-ISKEQLKDYVWKTLNSGKVVPGFGHGVLRKTVPRYTCQREFAMKHLPE 378

Query: 385 DEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRAL 444
           D +FQLVSKLYEV    L+   K+K PWPNVD HSG+LL YYGL E+ +YTVLFGVSRAL
Sbjct: 379 DPLFQLVSKLYEVFLLFLQNLAKLK-PWPNVDAHSGVLLNYYGLTEARYYTVLFGVSRAL 437

Query: 445 GTLSSLVWDRALGLPIERPKSVTTQWIREHFEK 477
           G  S L+WDRALGLP+ERPKSVT +W+    +K
Sbjct: 438 GICSQLIWDRALGLPLERPKSVTMEWLENQCKK 470


gb|AAS67338.1| citrate synthase [Desulfuromonas palmitatis]
(437 aa)

Score: 434 bits (1116), Expect: 3.03992e-120
Length: 437, Idn/Pos/Gap = 222/289/9 (50%/66%/2%)

Query:  40 TSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYETSLLDPQEG  99
           ++L+E +R KIE  R +   + + FG+  L   T++QA GG R +K +V + S LDP EG
Sbjct:   2 STLKETLRKKIEEHRPRTTRLVKEFGDVKLGDVTISQAIGGARGIKCLVTDISYLDPMEG  61

Query: 100 IRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPP 159
           IRFRG +IPE    LP+  P  + P  EG  W+LLTG++PT  Q   V +D K+R+ +P 
Sbjct:  62 IRFRGKTIPETFAALPKV-PGSDYPYVEGFWWMLLTGDVPTMEQTLEVVEDWKKRSQIPA 120

Query: 160 EVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGA-PKSTFWEYCLEDALTLIA 218
            V+ +L  LP +  HPM  FS A+  +Q +S  A+ YA G   K T WE   EDA  L+A
Sbjct: 121 YVIDVLRALPRDS-HPMAMFSAAIVAMQRDSVFAKNYAAGKFNKMTCWEDMYEDANELMA 179

Query: 219 RLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVLHADH 278
           +L  +AA IYR  + G  H+PA+   K+D MG   A  +G +   +D++ R+Y +LH+DH
Sbjct: 180 KLGPIAAYIYRMKYKGDTHIPADP--KLD-MGGNFAHMMGVD-KPYDDVARMYFILHSDH 235

Query: 279 EGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMT 338
           E GNVSAH   LV SALSD Y S+AAG+NGLAGPLHGLANQEVL W     +KLG +  T
Sbjct: 236 ESGNVSAHTTHLVASALSDAYYSYAAGINGLAGPLHGLANQEVLAWTQNFMDKLGGKVPT 295

Query: 339 TENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKH--LPHDEMFQLVSKLYE 396
            E L +  W+TL  G VIPG+GHAVLR+TDPRYT+QREF LK   L    +FQLVS ++E
Sbjct: 296 KEELEKALWDTLNSGQVIPGYGHAVLRKTDPRYTSQREFCLKTPGLKEYPLFQLVSMIFE 355

Query: 397 VVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRAL 456
           V P VL + GK KNPWPNVD  SG++  YYG+ E +FYTVLFGV RALG L+++ WDRAL
Sbjct: 356 VAPDVLLKHGKAKNPWPNVDAQSGVIQWYYGVTEYDFYTVLFGVGRALGCLANITWDRAL 415

Query: 457 GLPIERPKSVTTQWIRE 473
           G  IERPKSVTT  + +
Sbjct: 416 GYAIERPKSVTTAMLED 432


gb|EAA47374.1| hypothetical protein MG02617.4 [Magnaporthe grisea 70-15]
ref|XP_366541.1| hypothetical protein MG02617.4 [Magnaporthe grisea 70-15]
(458 aa)

Score: 434 bits (1115), Expect: 4.00352e-120
Length: 450, Idn/Pos/Gap = 224/305/14 (49%/67%/3%)

Query:  29 RAVRALSTSSATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMV  88
           R+ R  S SS   L+  ++S I   R  + +V+   G +V+    V    GGMR LKAMV
Sbjct:   8 RSTRNYSASSEPDLKTTLKSVIPAKRELLKKVKAH-GSKVIGEVKVENTIGGMRGLKAMV  66

Query:  89 YETSLLDPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVC 148
           +E S+LD  EGIRF G +I +CQR LP+ K +G + LPE + WLLLTG++P+ +QV  + 
Sbjct:  67 WEGSVLDADEGIRFHGRTIKDCQRELPKGK-TGTEMLPEAMFWLLLTGQVPSTNQVRVLS 125

Query: 149 QDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEY 208
           + L  +A +P  V ++LD+ P + +HPMTQF++AVS L H SK A+AYA G  K+ +WE 
Sbjct: 126 RQLAEQAQLPAFVNKMLDDFPRD-LHPMTQFAIAVSALNHTSKFAKAYADGLNKADYWEP 184

Query: 209 CLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGF--ELNE-FD 265
             +D+++L+A+LP +AA+IY N++ GG  +PAE ++   D     A  LG   + NE F 
Sbjct: 185 TFDDSISLLAKLPTIAAKIYHNSYKGGGALPAE-VDLEQDWSYNFAAMLGKGGKGNENFQ 243

Query: 266 ELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWL 325
           +L+RLYL LH DHEGGNVSAHA  LVGSALSDP+LS++AGL GLAGPLHGLA QEVLRW+
Sbjct: 244 DLLRLYLALHGDHEGGNVSAHATHLVGSALSDPFLSYSAGLQGLAGPLHGLAAQEVLRWI 303

Query: 326 LQMKEKLGNRPMT--TENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALK--H 381
           +QMKE +   P T   +++ +  W TL  G V+PG+GHAVLR+ DPR+ A  ++A     
Sbjct: 304 IQMKEAI---PATYSEKDVTDYLWSTLNSGRVVPGYGHAVLRKPDPRFQALMDYAASRPE 360

Query: 382 LPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVS 441
           +  D +FQLV    +V P VL++ GK KNP+PNVD  SG+L  +YG  E+ +YT  FGVS
Sbjct: 361 IAKDPVFQLVQLNSQVAPEVLKKHGKTKNPYPNVDSSSGVLFHHYGFHETLYYTATFGVS 420

Query: 442 RALGTLSSLVWDRALGLPIERPKSVTTQWI 471
           R LG L+ L+WDRALGLPIERPKS+  + I
Sbjct: 421 RGLGPLAQLIWDRALGLPIERPKSINLEGI 450


emb|CAG58031.1| unnamed protein product [Candida glabrata CBS138]
ref|XP_445131.1| unnamed protein product [Candida glabrata]
(463 aa)

Score: 433 bits (1113), Expect: 5.73137e-120
Length: 444, Idn/Pos/Gap = 230/293/18 (51%/65%/4%)

Query:  39 ATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYETSLLDPQE  98
           + SL+EA    +     ++   +  FG  V+   TV QA GGMR +  +V+E S+LDP+E
Sbjct:  10 SVSLKEAYARNLPAQAERLKRFKSEFGSTVIGEVTVEQALGGMRGVTGLVWEGSVLDPEE  69

Query:  99 GIRFRGFSIPECQRLLPRAKPSGE-QPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAV 157
           GI+FRG +I E +  L  A   GE +P PE L WLLLTG+IP E QV  + ++L  R  +
Sbjct:  70 GIKFRGLTIDEVRVSLGVA---GEREPQPEALFWLLLTGQIPNEDQVAQLSRELAARGEL 126

Query: 158 PPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLI 217
           P  V  LLD LP + +HPM Q S+AV+ L+ ES  A AY  G P+   WE+  EDAL LI
Sbjct: 127 PGHVETLLDTLPRD-LHPMAQLSIAVTALEGESHFARAYLAGVPRGELWEHTYEDALNLI 185

Query: 218 ARLPAVAARIYRNTFHGGKHVPAEK------IEKVDDMGMRLARSLGF----ELNEFDEL 267
           A+LPA+A RIY N F G +    +       ++   D    L R+LG     E  +F  L
Sbjct: 186 AKLPAIAGRIYHNVFGGAQGAQGQGTQGAFVLDPQADYSENLCRALGVQPDGETEDFHNL 245

Query: 268 MRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQ 327
           MRLYL +HADHEGGNVSAH   LVGSALS PYLSFAAGL+GLAGPLHG ANQEVL WLL 
Sbjct: 246 MRLYLTIHADHEGGNVSAHTTHLVGSALSSPYLSFAAGLDGLAGPLHGRANQEVLEWLLV 305

Query: 328 MKEKL---GNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPH 384
           +K +L   G      E +R+  W TL  G V+PG+GHAVLR+TDPR+ AQREF     P 
Sbjct: 306 LKGELVREGKTVTDREAIRQYLWRTLNSGKVVPGYGHAVLRKTDPRFLAQREFGRTRFPG 365

Query: 385 DEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRAL 444
           DE++QLVS +YEV P+VL+E GK +NP+PNVD HSG+LL +YGL + +FYTVLFG+SR  
Sbjct: 366 DELYQLVSTVYEVAPQVLKEHGKTRNPYPNVDAHSGVLLTHYGLDQPSFYTVLFGISRCF 425

Query: 445 GTLSSLVWDRALGLPIERPKSVTT 468
           G ++ L+ DRALG PIERPKS++T
Sbjct: 426 GVMAQLITDRALGAPIERPKSLST 449


emb|CAG78959.1| unnamed protein product [Yarrowia lipolytica CLIB99]
ref|XP_503380.1| hypothetical protein [Yarrowia lipolytica]
(459 aa)

Score: 432 bits (1112), Expect: 8.06916e-120
Length: 462, Idn/Pos/Gap = 234/307/15 (50%/66%/3%)

Query:  13 RDLRRAEKSWPSDVWKRAVRALSTSSATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDAC  72
           R  R A  S  S V KR     ++    +L+EA+ +K+E  +    +V+  + ++ L  C
Sbjct:   5 RTARVARTSVSSMVQKR----FASDLKGALKEAIPAKLELFK----KVKSEYSQKSLGDC  56

Query:  73 TVNQAYGGMRSLKAMVYETSLLDPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWL 132
            V    GGMR LK M++E S+LD  EGIRF G +I ECQ +LP+A   GE  LPE +LW 
Sbjct:  57 KVENLLGGMRGLKCMLWEGSVLDADEGIRFHGKTIKECQEVLPKAVEGGEM-LPESMLWF 115

Query: 133 LLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKM 192
           L TG++PTE QV  + ++L  +  VP  V ++LD LP   +HPMTQFS+AVS L H+SK 
Sbjct: 116 LFTGKVPTEEQVRGLSRELAEKGEVPEFVNKMLDNLP-PTLHPMTQFSMAVSALNHDSKF 174

Query: 193 AEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMR 252
           A+AY +G PKS +WEY  +D++ LIA+LP +AA+IY+N++ GG  +P  KI+   D    
Sbjct: 175 AKAYERGIPKSEYWEYTFDDSIDLIAKLPQIAAKIYQNSYLGGGPLPG-KIDLNRDWSYN 233

Query: 253 LARSLGF-ELNEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAG 311
            A  +G  +   F +L+RLY  LH DHEGGNVSAHA  LVGSALSDPYLS++AGL GLAG
Sbjct: 234 YAAMMGKGDETGFVDLLRLYFALHGDHEGGNVSAHATHLVGSALSDPYLSYSAGLQGLAG 293

Query: 312 PLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRY 371
           PLHGLA QEVLR++L M EK   +  + E+L +  W  L+ G VIPG+GHAVLR+ DPR+
Sbjct: 294 PLHGLAAQEVLRFILDM-EKNVPKGYSNEDLVKYLWSVLKSGRVIPGYGHAVLRKPDPRF 352

Query: 372 TAQREFA--LKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLV 429
            A   FA   + +  D +FQLVS+  EV   VL E GK KNP PNVD  SG+L  +YG+ 
Sbjct: 353 EALMNFANSRQEIRDDPVFQLVSRTSEVATGVLTEHGKTKNPHPNVDSSSGVLFHHYGIH 412

Query: 430 ESNFYTVLFGVSRALGTLSSLVWDRALGLPIERPKSVTTQWI 471
           E+ +YTV FGVSRALG L  LVWDR LGLPIERPKS++ + I
Sbjct: 413 ETLYYTVTFGVSRALGPLPQLVWDRILGLPIERPKSLSLEEI 454


emb|CAE76403.1| probable methylcitrate synthase [Neurospora crassa]
ref|XP_331681.1| hypothetical protein [Neurospora crassa]
gb|EAA35840.1| hypothetical protein [Neurospora crassa]
(470 aa)

Score: 431 bits (1107), Expect: 3.47509e-119
Length: 442, Idn/Pos/Gap = 219/299/14 (49%/67%/3%)

Query:  40 TSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYETSLLDPQEG  99
           T L+EA+     P + ++ +  +  G +VL    V    GGMR LKAM++E S+LD  EG
Sbjct:  36 TVLKEAI-----PEKRELFKKVKAHGNKVLGEVKVENTIGGMRGLKAMIWEGSVLDANEG  90

Query: 100 IRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPP 159
           IRF G +I +CQ+ LP+ K +G + LPE + WLLLTG++P+ +QV    ++L  +AA+P 
Sbjct:  91 IRFHGRTIKDCQKELPKGK-NGTEMLPEAMFWLLLTGKVPSTNQVRQFSRELAEQAALPD 149

Query: 160 EVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIAR 219
            V +LLD  P + +HPMTQF++AVS L H SK A+AY QG  K+ +WE   +D ++L+ +
Sbjct: 150 FVNKLLDGFPKD-LHPMTQFAIAVSALNHTSKFAKAYEQGLNKADYWEPTFDDCISLLGK 208

Query: 220 LPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGF---ELNEFDELMRLYLVLHA 276
           LP +AA+IY+N++ GG  +PAE ++   D     A  LG    E   F +L+RLYL LH 
Sbjct: 209 LPTIAAKIYQNSYKGGGALPAE-VDLEQDWAYNFAAMLGKPGKENENFQDLLRLYLALHG 267

Query: 277 DHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRP 336
           DHEGGNVSAH   LVGSALSDP+L+++AGL GLAGPLHGLA QEVLRW+LQMKE + +  
Sbjct: 268 DHEGGNVSAHTTHLVGSALSDPFLAYSAGLQGLAGPLHGLAAQEVLRWILQMKEAIPSS- 326

Query: 337 MTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKH--LPHDEMFQLVSKL 394
            T E++R   W TL  G V+PG+GHAVLR+ DPR+ A  ++A     +  D +FQLV K 
Sbjct: 327 YTDEDVRSYLWNTLNSGRVVPGYGHAVLRKPDPRFEALMDYAASRPKIAADPVFQLVLKN 386

Query: 395 YEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDR 454
            ++ P VL++ GK KNP+PNVD  SG+L  +YG  E+ +YT  FGVSR LG L+ L+WDR
Sbjct: 387 SQIAPEVLKQHGKTKNPYPNVDSSSGVLFHHYGFHETLYYTATFGVSRGLGPLAQLIWDR 446

Query: 455 ALGLPIERPKSVTTQWIREHFE 476
           ALGLPIERPKS+  + I +  E
Sbjct: 447 ALGLPIERPKSINLEGILKQVE 468


ref|YP_076371.1| citrate synthase [Symbiobacterium thermophilum IAM 14863]
dbj|BAD41527.1| citrate synthase [Symbiobacterium thermophilum IAM 14863]
(439 aa)

Score: 430 bits (1105), Expect: 5.59131e-119
Length: 437, Idn/Pos/Gap = 222/288/10 (50%/65%/2%)

Query:  40 TSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYETSLLDPQEG  99
           + L+  +  KIE  R +   + + FG  V+D  T+ +A GG R ++ +V + S LDP EG
Sbjct:   2 SQLKATLVRKIEEHRPRTQRLLKEFGHVVIDEVTIEKAIGGARDVRCLVTDISYLDPMEG  61

Query: 100 IRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPP 159
           IRFRG +I E    LP+A P GE P  E   + LLTGE+PT+ QV+ V  + K R  VP 
Sbjct:  62 IRFRGKTIEETFAALPKA-PGGEYPTVEAFWFFLLTGEVPTQEQVDEVIAEWKERRNVPQ 120

Query: 160 EVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGA-PKSTFWEYCLEDALTLIA 218
            V  ++  LP +  HPMT  S  +  +Q ESK A  Y  G   K   WEY  EDA  L+A
Sbjct: 121 YVYDVIRALPKDS-HPMTMLSAGILAMQRESKFARYYHSGEYNKQRAWEYMYEDASDLVA 179

Query: 219 RLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVLHADH 278
           R+P +AA IYR  +    H+P +      DMG   A  +G     +D++ R+Y +LH+DH
Sbjct: 180 RIPMIAAYIYRYKYKDDVHIPPDPNL---DMGANFAHMMGVP-KPYDDVSRMYFILHSDH 235

Query: 279 EGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGN--RP 336
           E GNVSAH   LV SALSD YL+++A LNGLAGPLHGLANQEVLRW++  + KLG    P
Sbjct: 236 ESGNVSAHTGHLVASALSDAYLAYSAALNGLAGPLHGLANQEVLRWIMDFQAKLGEGVEP 295

Query: 337 MTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSKLYE 396
            T EN+ +  W+TL  G VIPG+GHAVLR+TDPRYTAQREF LKH+P D +F+LVS +YE
Sbjct: 296 -TRENVTQALWDTLNAGQVIPGYGHAVLRKTDPRYTAQREFCLKHMPDDPLFKLVSMIYE 354

Query: 397 VVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRAL 456
           V P VL + GK KNPWPNVD  SG++  +YG+ E +FYTVLFGV RALG ++++VWDRAL
Sbjct: 355 VAPGVLMQHGKAKNPWPNVDAQSGVIQWHYGVREWDFYTVLFGVGRALGVMANIVWDRAL 414

Query: 457 GLPIERPKSVTTQWIRE 473
           G PIERPKSVTT+ + +
Sbjct: 415 GYPIERPKSVTTEMLEQ 431


gb|AAS67337.1| citrate synthase [Desulfuromonas acetoxidans]
(437 aa)

Score: 428 bits (1100), Expect: 1.95461e-118
Length: 438, Idn/Pos/Gap = 219/287/11 (50%/65%/2%)

Query:  40 TSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYETSLLDPQEG  99
           ++L+E ++ KI+  R +   + +  G+  L   T+ QA GG R +K +V + S LDP EG
Sbjct:   2 STLKEVLKQKIDAHRPRTTRLVKECGDTTLGEVTIAQAIGGARGIKCLVTDISYLDPMEG  61

Query: 100 IRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPP 159
           IRFRG +IPE    LP+  P  + P  EG  +LLLTG++PT  Q   V +D K+R+ VP 
Sbjct:  62 IRFRGMTIPETFAALPKV-PGSDYPYVEGFWYLLLTGDVPTMEQTLEVVEDWKQRSQVPE 120

Query: 160 EVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGA-PKSTFWEYCLEDALTLIA 218
            V+ +L  +P +  HPM  FS A+  +Q +S  A  YA G   K T WE  LED+  L+A
Sbjct: 121 YVIDVLRAMPRDS-HPMAMFSAAIVAMQRDSVFASNYAAGKFNKMTCWEDMLEDSNDLMA 179

Query: 219 RLPAVAARIYRNTFHGGKHV-PAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVLHAD 277
           +L  +AA IYR  + G  H+ P  ++    DMG + A  +G + +E+ ++ R+Y +LH+D
Sbjct: 180 KLGPIAAYIYRMKYKGDTHIAPDPEL----DMGGQFAHLIG-QCDEYKDVARMYFILHSD 234

Query: 278 HEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPM 337
           HE GNVSAH   LV SALSD Y S+AAG+NGLAGPLHGLANQEVL W     EKLG +  
Sbjct: 235 HESGNVSAHTTHLVASALSDAYYSYAAGINGLAGPLHGLANQEVLAWTQNFMEKLGGKVP 294

Query: 338 TTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKH--LPHDEMFQLVSKLY 395
           T + L+   W+TL  G VIPG+GHAVLR+TDPRYT+QREF L    L  D +FQLV+ +Y
Sbjct: 295 TKDELKAALWDTLNSGQVIPGYGHAVLRKTDPRYTSQREFCLNTPGLKEDPLFQLVAMIY 354

Query: 396 EVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRA 455
           EV P VL E GK KNPWPNVD  SG++  YYGL E +FYTVLFGV RALG L+++ WDRA
Sbjct: 355 EVAPDVLLEHGKAKNPWPNVDAQSGVIQWYYGLTEYDFYTVLFGVGRALGCLANITWDRA 414

Query: 456 LGLPIERPKSVTTQWIRE 473
           LG  IERPKSVTT  + +
Sbjct: 415 LGYAIERPKSVTTAMLED 432


gb|EAA67271.1| conserved hypothetical protein [Gibberella zeae PH-1]
ref|XP_380351.1| conserved hypothetical protein [Gibberella zeae PH-1]
(472 aa)

Score: 426 bits (1095), Expect: 7.00613e-118
Length: 445, Idn/Pos/Gap = 216/300/10 (48%/67%/2%)

Query:  37 SSATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYETSLLDP  96
           ++   L+  +R  I   R  + +V+     +VL    V    GGMR LKAMV+E S+LD 
Sbjct:  31 TAEPDLKATLREAIPAKRELLKKVKAH-SNKVLGEVKVENTLGGMRGLKAMVWEGSVLDA  89

Query:  97 QEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAA 156
            EGIRF G +I +CQ+ LP+ K +G + LPE + WLLLTG++P+ +QV    ++L  +A 
Sbjct:  90 NEGIRFHGRTIKDCQKELPKGK-TGTEMLPEAMFWLLLTGQVPSVNQVRGFSRELAEKAQ 148

Query: 157 VPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTL 216
           +P  V ++L++ P + +HPMTQF++AVS L +ESK A+AY QG  K+ +WE   +D ++L
Sbjct: 149 IPEFVSKMLNDFPKD-LHPMTQFAMAVSALNYESKFAKAYEQGINKADYWEPTFDDCISL 207

Query: 217 IARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGF---ELNEFDELMRLYLV 273
           +A+LP +AA+IY+N + GG  +PAE ++   D     A  LG    E   F +L+RLYL 
Sbjct: 208 LAKLPTIAAKIYQNAYRGGGALPAE-VDLEQDWSYNFAAMLGKGGKENENFQDLLRLYLA 266

Query: 274 LHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLG 333
           LH DHEGGNVSAHA  LVGSALSDP+LS++AGL GLAGPLHGLA QEVLRW++QMKE + 
Sbjct: 267 LHGDHEGGNVSAHATHLVGSALSDPFLSYSAGLQGLAGPLHGLAAQEVLRWIIQMKEAIP 326

Query: 334 NRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALK--HLPHDEMFQLV 391
           +   T +++ +  W TL  G V+PG+GHAVLR+ DPR+ A  ++A     + +D +FQLV
Sbjct: 327 SN-YTEQDVNDYLWSTLNSGRVVPGYGHAVLRKPDPRFEALMDYAAARPEIANDPVFQLV 385

Query: 392 SKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLV 451
            K   + P VL++ GK KNP+PNVD  SG+L  +YG  E+ +YT  FGVSR LG L+ L+
Sbjct: 386 EKNSRIAPEVLKKHGKTKNPYPNVDSSSGVLFHHYGFHETLYYTATFGVSRGLGPLAQLI 445

Query: 452 WDRALGLPIERPKSVTTQWIREHFE 476
           WDRALGLPIERPKS+  + I +  E
Sbjct: 446 WDRALGLPIERPKSINLEGILKQVE 470


ref|ZP_00301235.1| COG0372: Citrate synthase [Geobacter metallireducens GS-15]
gb|AAS67339.1| citrate synthase [Geobacter metallireducens]
(441 aa)

Score: 423 bits (1088), Expect: 5.32137e-117
Length: 441, Idn/Pos/Gap = 218/288/14 (49%/65%/3%)

Query:  41 SLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYETSLLDPQEGI 100
           +L+E ++ KIE  R +   + + FG+ V+D  T++QA GG R ++++V + S LDPQEGI
Sbjct:   2 ALKETLKQKIEEFRPRTTRLVKEFGKVVIDQVTIDQAIGGARDIRSLVTDISYLDPQEGI  61

Query: 101 RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPE 160
           RFRG +IPE    LP+A  S + P  E   + LLTGE+PT++QV+ V  + K R  VP  
Sbjct:  62 RFRGKTIPETFEALPKASGS-DYPTVESFWYFLLTGEVPTQAQVDEVVAEWKTRQVVPQY 120

Query: 161 VLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGA-PKSTFWEYCLEDALTLIAR 219
           V   +  LP E  HPM   SV +  LQ +SK A  Y  G   K T WEY  EDA  L+AR
Sbjct: 121 VFDAISALPKES-HPMVMLSVGILALQKDSKFAGFYNSGKFNKMTAWEYVYEDASDLVAR 179

Query: 220 LPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVLHADHE 279
           +P +AA IY   + GGK      I+   D G   AR +G +  E++++ R+Y +LH+DHE
Sbjct: 180 IPIIAAFIYNLKYRGGKQ---SAIDPTADCGANFARMIG-QCKEYEDVARMYFILHSDHE 235

Query: 280 GGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKL-GNRPMT 338
            GNVSAH   LV SALSDPY +++AGLNGLAGPLHGLANQEVL W ++ ++K   +   T
Sbjct: 236 SGNVSAHTTHLVHSALSDPYYAYSAGLNGLAGPLHGLANQEVLDWTIKFQQKYCKDVEPT 295

Query: 339 TENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKH--LPHDEMFQLVSKLYE 396
            E + +  W+TL  G V+PG+GHAVLR+TDPRY +QREF LK   L  D +F+LV+ ++E
Sbjct: 296 KELVTKALWDTLNAGQVVPGYGHAVLRKTDPRYMSQREFCLKTPGLKDDPLFKLVAMIFE 355

Query: 397 VVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRAL 456
             P VL E GK KNPWPNVD  SG++  YYGL E +FYTVLFGV RALG ++++ WDR L
Sbjct: 356 TAPGVLMEHGKAKNPWPNVDAQSGVIQWYYGLREWDFYTVLFGVGRALGCMANITWDRGL 415

Query: 457 GLPIERPKSVTT----QWIRE 473
           G  IERPKSVTT    +W  E
Sbjct: 416 GYAIERPKSVTTPMLEKWAEE 436


ref|NP_952159.1| citrate synthase [Geobacter sulfurreducens PCA]
gb|AAR34432.1| citrate synthase [Geobacter sulfurreducens PCA]
gb|AAS67341.1| citrate synthase [Geobacter sulfurreducens]
(441 aa)

Score: 422 bits (1084), Expect: 1.68301e-116
Length: 441, Idn/Pos/Gap = 217/288/14 (49%/65%/3%)

Query:  41 SLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYETSLLDPQEGI 100
           +L+E ++ KIE  R +   + + FG+ ++D  T++Q  GG R ++ +V + S LDPQEGI
Sbjct:   2 ALKETLKQKIEEHRPRTTRLVKEFGKVIIDQVTIDQCIGGARDIRCLVTDISYLDPQEGI  61

Query: 101 RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPE 160
           RFRG +IPE    LP+A  S + P  E   + LLTGE+PT++QV+ V  + K R  VP  
Sbjct:  62 RFRGKTIPETFEALPKAAGS-DYPTVESFWYFLLTGEVPTQAQVDEVVAEWKVRQEVPQY 120

Query: 161 VLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGA-PKSTFWEYCLEDALTLIAR 219
           V   +  LP +  HPM   SV +  LQ +SK A  Y  G   K T WEY  EDA  L+AR
Sbjct: 121 VFDAIRALPRDS-HPMVMLSVGILALQKDSKFAGFYNSGKFNKMTAWEYVYEDAYDLVAR 179

Query: 220 LPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVLHADHE 279
           +P +AA IY   + G K +P   I+   D G   AR +G +  E++++ R+Y +LH+DHE
Sbjct: 180 IPVIAAFIYNLKYKGDKQLP---IDPSADCGANFARMIG-QCKEYEDVARMYFILHSDHE 235

Query: 280 GGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKL-GNRPMT 338
            GNVSAH   LV SALSDPY +++AGLNGLAGPLHGLANQEVL W ++ +EK   +   T
Sbjct: 236 SGNVSAHTTHLVHSALSDPYYAYSAGLNGLAGPLHGLANQEVLDWTIKFQEKYCKDVEPT 295

Query: 339 TENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKH--LPHDEMFQLVSKLYE 396
            E + +  W+TL  G V+PG+GHAVLR+TDPRYT+QREF LK   L  D +F+LV+ ++E
Sbjct: 296 KELVTKALWDTLNAGQVVPGYGHAVLRKTDPRYTSQREFCLKTPGLKDDPLFKLVAMIFE 355

Query: 397 VVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRAL 456
             P VL E GK KNPWPNVD  SG++  YYGL E +FYTVLFGV RALG ++++ WDR L
Sbjct: 356 TAPGVLMEHGKAKNPWPNVDAQSGVIQWYYGLREWDFYTVLFGVGRALGCMANITWDRGL 415

Query: 457 GLPIERPKSVTT----QWIRE 473
           G  IERPKSVTT    +W  E
Sbjct: 416 GYAIERPKSVTTPMLEKWAEE 436


gb|AAS67336.1| citrate synthase [Pelobacter carbinolicus]
(434 aa)

Score: 418 bits (1074), Expect: 2.43026e-115
Length: 428, Idn/Pos/Gap = 206/282/6 (48%/65%/1%)

Query:  40 TSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYETSLLDPQEG  99
           + L++ +  KIE  R +V  + + +G+  LD  T+ QA GG+R +K +V + S LDP+EG
Sbjct:   2 SQLKDTLFRKIEEQRPRVTRLLKEYGQVELDKVTIAQAIGGVRGVKCLVTDISYLDPEEG  61

Query: 100 IRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPP 159
           +RFRG +IPE    LP+  P  E P  EG  + LLTGE+PT  Q   V  D + R  VP 
Sbjct:  62 VRFRGKTIPETFAALPKV-PGSEYPYVEGFWYFLLTGEVPTMEQTLEVVADFQARRPVPQ 120

Query: 160 EVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIAR 219
            V   L  +P + +HPM   S A+ ++Q ES  A+ Y +G  K   W+   ED+  L+A+
Sbjct: 121 YVFDALRAMPRD-LHPMAMLSAAIVVMQGESIFAKRYNEGMGKGDLWDPMYEDSCNLLAK 179

Query: 220 LPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVLHADHE 279
           LPA+AA IYR  + G   +P++      D G   A  +G     +D++ R+Y +LH+DHE
Sbjct: 180 LPAIAAYIYRLKYKGDTPIPSDPEL---DFGGDFAHMMGIA-PPYDDVARMYFILHSDHE 235

Query: 280 GGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTT 339
            GNVSAH  RLV SAL+D Y S +AG+NGL+GPLHGLANQEVLRW+    EKLG +  T 
Sbjct: 236 SGNVSAHTTRLVASALADAYYSLSAGVNGLSGPLHGLANQEVLRWIQSKMEKLGGKLPTE 295

Query: 340 ENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSKLYEVVP 399
           E L    W+TL  G VIPG+GHAVLRRTDPR++AQ EF  K+LP+D++++LV  LY+V P
Sbjct: 296 EELERYLWDTLNSGQVIPGYGHAVLRRTDPRFSAQMEFCEKYLPNDDLYRLVKMLYKVAP 355

Query: 400 RVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP 459
           +VL+E GK +NPWPNVD  SG++  +YG+ +  +YTVLF V RALG L+++ WDRALG P
Sbjct: 356 KVLQEHGKARNPWPNVDAQSGVIQWHYGITQYEYYTVLFAVGRALGVLANITWDRALGYP 415

Query: 460 IERPKSVT 467
           +ERPKS+T
Sbjct: 416 LERPKSIT 423


ref|ZP_00300446.1| COG0372: Citrate synthase [Geobacter metallireducens GS-15]
gb|AAS67340.1| citrate synthase [Geobacter metallireducens]
(438 aa)

Score: 416 bits (1070), Expect: 5.6447e-115
Length: 434, Idn/Pos/Gap = 210/282/8 (48%/64%/1%)

Query:  42 LQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYETSLLDPQEGIR 101
           L+E ++ KIE  R +   + + FG+  +D  T+ Q  GG R ++++V + S LDPQEGIR
Sbjct:   3 LKETLKQKIEEFRPRTTRLVKEFGKVKIDEVTIEQCIGGARDIRSLVTDISYLDPQEGIR  62

Query: 102 FRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEV 161
           FRG +IPE    LP+A P  + P  E   + LLTGE+PT++QV+ V  + K R  VP  V
Sbjct:  63 FRGKTIPETFAALPKA-PGSDYPTVESFWYFLLTGEVPTQAQVDEVLTEWKVRQEVPQYV 121

Query: 162 LRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGA-PKSTFWEYCLEDALTLIARL 220
              +  LP +  HPM   SV ++ +Q +SK A  Y  G   K + WE   EDA  ++AR+
Sbjct: 122 FDTIRTLPRDS-HPMAMLSVGITAMQRDSKFAALYNAGKFNKLSAWESVYEDACDIVARI 180

Query: 221 PAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVLHADHEG 280
           P +AA IY   + G K +    I+   DMG   A  +  + + + ++ R+Y +LH+DHE 
Sbjct: 181 PVIAAFIYNLKYKGDKQI---AIDPALDMGANFAHMID-QGDAYKDVARMYFILHSDHES 236

Query: 281 GNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKL-GNRPMTT 339
           GNVSAH   LV SALSDPY ++AAGLNGLAGPLHG ANQEVL W ++ +EK   ++  T 
Sbjct: 237 GNVSAHTTHLVHSALSDPYYAYAAGLNGLAGPLHGRANQEVLDWTIKFQEKYCKDQEPTK 296

Query: 340 ENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSKLYEVVP 399
           E +    W+TL  G VIPG+GHAVLR+TDPRY +QREF  KHLP D +F+LVS ++EV P
Sbjct: 297 ELITRALWDTLNSGQVIPGYGHAVLRKTDPRYISQREFCQKHLPEDPLFKLVSMIFEVAP 356

Query: 400 RVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP 459
            VL E GK KNPWPNVD  SG++  +YG+ E +FYTVLFGV RALG ++++ WDR LG  
Sbjct: 357 GVLTEHGKTKNPWPNVDAQSGVIQWHYGVKEWDFYTVLFGVGRALGCMANITWDRGLGYA 416

Query: 460 IERPKSVTTQWIRE 473
           IERPKSVTT  + E
Sbjct: 417 IERPKSVTTPMLEE 430


ref|NP_650152.1| CG14740-PA [Drosophila melanogaster]
gb|AAF54748.2| CG14740-PA [Drosophila melanogaster]
gb|AAL13648.1| GH19789p [Drosophila melanogaster]
(478 aa)

Score: 408 bits (1049), Expect: 1.75674e-112
Length: 430, Idn/Pos/Gap = 199/285/4 (46%/66%/0%)

Query:  39 ATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYETSLLDPQE  98
            + L+  +  KI   R +   ++   G++++   +VN   GGMR L  +  ETS LD  +
Sbjct:  30 GSGLKAKLAKKIPIEREKFLGIKCLHGKKIIGQISVNSVIGGMRGLPLLFCETSSLDKNK  89

Query:  99 GIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVP 158
           GI +RG  + +    LPR +   ++  PEG  +LL +G +PT+ + + V  +  +R +VP
Sbjct:  90 GIYYRGKLLKDVCAKLPRVQEGTQEGTPEGCFFLLTSGSMPTKKEAQEVTNEWLKRGSVP 149

Query: 159 PEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIA 218
              LR++D +  +R+HPM Q   A + L  +S+  EAY +GA ++ +W+Y  ED++ LIA
Sbjct: 150 RYCLRMIDSM-DKRVHPMAQLCAASACLNPQSQFVEAYTKGARRADYWKYSYEDSMNLIA 208

Query: 219 RLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVLHADH 278
            LP VAA IY N F  G+   + ++   +D      R LG    +F +LMRLY++LHADH
Sbjct: 209 MLPTVAAAIYSNVFRDGEG--SREVNYEEDWSGNFCRMLGLPEKDFVDLMRLYMILHADH 266

Query: 279 EGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMT 338
           E GNVSAHA  LVG+ALSDP+LSF+A + GLAGPLHGLANQEVL WL ++++ +G+ P +
Sbjct: 267 ESGNVSAHACHLVGTALSDPFLSFSASMCGLAGPLHGLANQEVLVWLTKLRKAIGDDP-S 325

Query: 339 TENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSKLYEVV 398
            E L++   +TL+ G VIPG+GHAVLR TDPR+  Q EFA+KH   D   +LV++L++++
Sbjct: 326 DEELKKFIDDTLKGGQVIPGYGHAVLRDTDPRFVLQNEFAMKHCKDDPGVKLVTRLWKII 385

Query: 399 PRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGL 458
           P VL++  KV NP+PNVD HSG+LL++Y L E  FYTVLFGVSRALG LS L+W RALG 
Sbjct: 386 PEVLKKLNKVANPYPNVDAHSGVLLQHYCLKELKFYTVLFGVSRALGVLSQLIWSRALGA 445

Query: 459 PIERPKSVTT 468
           PIERPKS ++
Sbjct: 446 PIERPKSFSS 455


gb|EAA58179.1| hypothetical protein AN6650.2 [Aspergillus nidulans FGSC A4]
emb|CAB53336.1| methylcitrate synthase [Emericella nidulans]
ref|XP_410787.1| hypothetical protein AN6650.2 [Aspergillus nidulans FGSC A4]
sp|Q9TEM3|PRPC_EMENI 2-methylcitrate synthase, mitochondrial precursor (Methylcitrate synthase) (Citrate synthase 2)
(460 aa)

Score: 406 bits (1043), Expect: 8.79168e-112
Length: 470, Idn/Pos/Gap = 219/298/31 (46%/63%/6%)

Query:   2 HCARFVLALGRRDLRRAEKSWPSDVWKRAVRALSTSSATSLQEAVRSKIEPMRAQVHEVR  61
           H +R    +GRR    AE                      L+ A+++ I   R  + EV+
Sbjct:  10 HASRLAQTIGRRGYATAEPD--------------------LKSALKAVIPAKRELLAEVK  49

Query:  62 ERFGEEVLDACTVNQAYGGMRSLKAMVYETSLLDPQEGIRFRGFSIPECQRLLPRAKPSG 121
           ++ G+EV+    V+   GGMR LK+M++E S+LD  EGIRF G +I +CQ+ LP+  P+G
Sbjct:  50 KQ-GDEVIGEVKVSNVIGGMRGLKSMLWEGSVLDADEGIRFHGKTIKDCQKELPKG-PTG 107

Query: 122 EQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSV 181
            + LPE + WLLLTGE+P+ SQV +  + L   + +P  +L L    P + MHPMTQ S+
Sbjct: 108 TEMLPEAMFWLLLTGEVPSTSQVRAFSKQLAEESHLPDHILDLAKSFP-KHMHPMTQISI 166

Query: 182 AVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAE 241
             + L  ESK A+ Y +G  K+ +WE   +DA++L+A++P VAA ++R   +    V  +
Sbjct: 167 ITAALNTESKFAKLYEKGINKADYWEPTFDDAISLLAKIPRVAALVFRP--NEIDVVGRQ 224

Query: 242 KIEKVDDMGMRLARSLG---FELNEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDP 298
           K++   D     A  LG       +F +L+RLYL LH DHEGGNVSAHA  LVGSALSDP
Sbjct: 225 KLDPAQDWSYNFAELLGKGGANNADFHDLLRLYLALHGDHEGGNVSAHATHLVGSALSDP 284

Query: 299 YLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPG 358
           +LS++AGL GLAGPLHGLA QEVLRW+L M+EK+G +  T E++R   W+TL+ G V+PG
Sbjct: 285 FLSYSAGLLGLAGPLHGLAAQEVLRWILAMQEKIGTK-FTDEDVRAYLWDTLKSGRVVPG 343

Query: 359 FGHAVLRRTDPRYTAQREFAL--KHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVD 416
           +GH VLR+ DPR+ A  +FA   K +  + +FQLV K  E+ P VL E GK KNP PNVD
Sbjct: 344 YGHGVLRKPDPRFQALMDFAATRKDVLANPVFQLVKKNSEIAPGVLTEHGKTKNPHPNVD 403

Query: 417 QHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLPIERPKSV 466
             SG+L  +YG  +  +YTV FGVSRALG L  L+WDRALGLPIERPKS+
Sbjct: 404 AASGVLFYHYGFQQPLYYTVTFGVSRALGPLVQLIWDRALGLPIERPKSI 453


dbj|BAA14145.1| citrate synthase precursor [Tetrahymena thermophila]
sp|P24118|CISY_TETTH Citrate synthase, mitochondrial precursor (14 NM filament-forming protein)
pir||JC5625 14-nm filament protein/citrate synthase (EC 4.1.3.-) precursor - Tetrahymena thermophila
(462 aa)

Score: 405 bits (1041), Expect: 1.46256e-111
Length: 446, Idn/Pos/Gap = 198/297/11 (44%/66%/2%)

Query:  38 SATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYETSLLDPQ  97
           S T+L++ +   I   +A++ EV+E++G++V+   TV Q  GGMR +K ++ + S  DP 
Sbjct:  22 SQTNLKKVIAEIIPQKQAELKEVKEKYGDKVVGQYTVKQVIGGMRGMKGLMSDLSRCDPY  81

Query:  98 EGIRFRGFSIPECQRLLPRAKP-----SGEQPLPEGLLWLLLTGEIPTESQVESVCQDLK 152
           +GI FRG++IP+ +  LP+A P     + ++PLPEG+ WLL+TG++PT +QV+++  + +
Sbjct:  82 QGIIFRGYTIPQLKEFLPKADPKAADQANQEPLPEGIFWLLMTGQLPTHAQVDALKHEWQ 141

Query: 153 RRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGA-PKSTFWEYCLE 211
            R  V  + +  +  LP + +H MT  S+A+  LQ +SK A+ Y +G   K  +WE   E
Sbjct: 142 NRGTVNQDCVNFILNLPKD-LHSMTMLSMALLYLQKDSKFAKLYDEGKISKKDYWEPFYE 200

Query: 212 DALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRLY 271
           D++ LIA++P VAA IYR+ +   K + ++   K+D  G   A  +GFE +   E +R Y
Sbjct: 201 DSMDLIAKIPRVAAIIYRHKYRDSKLIDSD--SKLDWAG-NYAHMMGFEQHVVKECIRGY 257

Query: 272 LVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEK 331
           L +H DHEGGNVSAH   LVGSALSDPYLS++AG+NGLAGPLHGLANQEVL+WLLQ  E+
Sbjct: 258 LSIHCDHEGGNVSAHTTHLVGSALSDPYLSYSAGVNGLAGPLHGLANQEVLKWLLQFIEE 317

Query: 332 LGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLV 391
            G + ++ +++ +     +  G V+PG+GHAVLR TDPR+  Q +F+  HL  D+M +L+
Sbjct: 318 KGTK-VSDKDIEDYVDHVISSGRVVPGYGHAVLRDTDPRFHHQVDFSKFHLKDDQMIKLL 376

Query: 392 SKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLV 451
            +  +V+P+ L    K+ NP+PNVD HSG+LL   GL E  +YTV+F VSRALG +++L+
Sbjct: 377 HQCADVIPKKLLTYKKIANPYPNVDCHSGVLLYSLGLTEYQYYTVVFAVSRALGCMANLI 436

Query: 452 WDRALGLPIERPKSVTTQWIREHFEK 477
           W RA GLPIERP S   +W  + + +
Sbjct: 437 WSRAFGLPIERPGSADLKWFHDKYRE 462


gb|EAK82252.1| hypothetical protein UM01627.1 [Ustilago maydis 521]
ref|XP_399242.1| hypothetical protein UM01627.1 [Ustilago maydis 521]
(474 aa)

Score: 404 bits (1038), Expect: 3.31307e-111
Length: 447, Idn/Pos/Gap = 210/293/10 (46%/65%/2%)

Query:  37 SSATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYETSLLDP  96
           +S  SL++AV   I   + Q+ +++   GE  L    +    GGMR LK M++E S+LD 
Sbjct:  32 ASTKSLKDAVAEIIPAKQEQLKKLKAEHGESKLGEIQLQHLLGGMRGLKVMLWEGSVLDS  91

Query:  97 QEGIRFRGFSIPECQRLLPRAKP---SGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKR 153
           + GI F G SIP+ Q++LP A     +G + LPE +LWLLLTG +P++ +V+ +  +L  
Sbjct:  92 ETGITFHGKSIPDSQKVLPTAADLGLNGNEILPESMLWLLLTGNVPSKDEVKGLSAELAA 151

Query: 154 RAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDA 213
           + A+P  V +++D  P + +HPMTQF+ AV+ L H+SK A AYA+G  K+ +W   LED+
Sbjct: 152 KGALPAHVEKIIDSFP-KTLHPMTQFAAAVAALNHDSKFAAAYAKGIKKTEYWAPVLEDS 210

Query: 214 LTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNE-FDELMRLYL 272
           + LIA+LPAVAARIY N F  G+    + I+   D+    +  +G+  N+   + +RLY+
Sbjct: 211 IDLIAKLPAVAARIYYNVF--GRGDGKQAIDSNLDLIGNYSNMIGYGDNQGMTDYLRLYI 268

Query: 273 VLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKL 332
            +H DHEGGNVSAH   LVGSALSDPYLS++A L GLAGPLHGLANQEVL W L M+E +
Sbjct: 269 AIHGDHEGGNVSAHTAHLVGSALSDPYLSYSAALLGLAGPLHGLANQEVLGWALSMQEAV 328

Query: 333 GNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREF--ALKHLPHDEMFQL 390
           G    + E ++E  W TL+ G V+PG+GHAVLR+ DPR+TA  +F      L    + +L
Sbjct: 329 GENA-SEEQIKEYLWSTLKSGRVVPGYGHAVLRQPDPRFTALSKFCDTRPELRDSSIVKL 387

Query: 391 VSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSL 450
           V K+ +V P VL+E GK KNP+PNVD  SG +L  YGL E  +YTV+FG+SRA+G L  L
Sbjct: 388 VQKVSQVAPGVLKEHGKTKNPFPNVDAASGCVLYQYGLTEFTYYTVIFGISRAIGALPQL 447

Query: 451 VWDRALGLPIERPKSVTTQWIREHFEK 477
           V DR LG+PIERPKS++   +    +K
Sbjct: 448 VADRYLGMPIERPKSMSMDSLEAFLKK 474


emb|CAA59009.1| citrate (si)-synthase [Populus trichocarpa X Populus deltoides]
pir||T09334 citrate (si)-synthase (EC 4.1.3.7), mitochondrial - western balsam poplar x cottonwood
(339 aa)

Score: 397 bits (1020), Expect: 3.6948e-109
Length: 340, Idn/Pos/Gap = 198/245/5 (58%/72%/1%)

Query: 138 IPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYA 197
           +PT+ QV ++ ++L+ RA V   V + +D LP    HPMTQF+  V  LQ +S+  +AY 
Sbjct:   1 MPTKEQVGALSKELRDRALVHDYVFKAIDALP-VTAHPMTQFATGVMALQVQSEFQKAYE  59

Query: 198 QGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSL 257
           +G  KS +WE   ED+L+LIAR+P VA+ IYR  +  GK +P      +   G   +  L
Sbjct:  60 KGIHKSKYWEPTYEDSLSLIARVPIVASYIYRRIYKDGKVIPMNDSLVI---GGNFSHML 116

Query: 258 GFELNEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLA 317
           GF+  E  ELMRLY+  H+DHEGGNVSAH   LV SALSDPYLSFAA LNGLAGPLHGLA
Sbjct: 117 GFDSPEMQELMRLYVTNHSDHEGGNVSAHTGHLVASALSDPYLSFAAALNGLAGPLHGLA 176

Query: 318 NQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREF 377
           NQEVL W+  + E+ G   +TTE L++  W+TL  G V+PGFGH VLR+T PRYT QREF
Sbjct: 177 NQEVLLWIKSVVEECGEN-ITTEQLKDYVWKTLNSGKVVPGFGHGVLRKTVPRYTCQREF 235

Query: 378 ALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVL 437
           ALKHLP D +FQLVSKLYEVVP VL + GKVKNPWPNVD HSG+LL YYGL E+ +YTVL
Sbjct: 236 ALKHLPDDPLFQLVSKLYEVVPPVLTQLGKVKNPWPNVDAHSGVLLNYYGLTEARYYTVL 295

Query: 438 FGVSRALGTLSSLVWDRALGLPIERPKSVTTQWIREHFEK 477
           FGVSR++G  S L+WDRALGLP+ERPKSVT + +  H +K
Sbjct: 296 FGVSRSIGICSQLIWDRALGLPLERPKSVTMELLENHCKK 335


emb|CAG99679.1| unnamed protein product [Kluyveromyces lactis NRRL Y-1140]
ref|XP_454592.1| unnamed protein product [Kluyveromyces lactis]
(473 aa)

Score: 384 bits (986), Expect: 3.37469e-105
Length: 460, Idn/Pos/Gap = 205/284/25 (44%/61%/5%)

Query:  35 STSSATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYETSLL  94
           S+    +L+ A+   I   R ++  +++ F +  +   T+     GMR  ++M +E++ L
Sbjct:  14 SSRHLLNLKAAIADVIPKRREELLHIKKNFSDVKVGDITIGSVINGMRGNQSMYWESTTL  73

Query:  95 DPQEGIRFRGFSIPECQRLLPRAKPSGEQP--LPEGLLWLLLTGEIPTESQVESVCQDLK 152
           DP EGIRF G +I ECQ+LLP A     +   LPE +LWLL+TGE+P+E QV  + Q+L 
Sbjct:  74 DPNEGIRFHGKTIAECQKLLPGAPEDNGKGEFLPESMLWLLMTGEVPSEEQVRKLTQELA 133

Query: 153 RRAA-VPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGA-PKSTFWEYCL 210
            R A +PP   +LL  LP + MHPMTQ ++A++ +   S  AE Y +G+  K  +WEY  
Sbjct: 134 ERGAKLPPHTEKLLTSLPRD-MHPMTQLAIALASMNKGSIFAEKYQEGSIGKMDYWEYVY 192

Query: 211 EDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFEL--------- 261
           ED L LIA LP +  +IY N  + G+ +    +EK  D    +A  LG  +         
Sbjct: 193 EDVLNLIAALPKITGKIYSNIVNDGEPLGHYNVEK--DWSYNIASLLGMTVSDSVNMHSL 250

Query: 262 -----NEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGL 316
                N+F  L+RLY  +H DHEGGNVSAH   LVGSALSDPYLS+++G+ GLAGPLHGL
Sbjct: 251 TQERSNDFVNLVRLYCGIHVDHEGGNVSAHTTHLVGSALSDPYLSYSSGIMGLAGPLHGL 310

Query: 317 ANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQRE 376
           A QEV+R+L++M EK  +     + + E  W+ L    VIPG+GHAVLR+ DPR+ A   
Sbjct: 311 AAQEVVRFLVEM-EKDVDSVENVKQVEEYLWKVLNSSRVIPGYGHAVLRKPDPRFDAMLN 369

Query: 377 FALK---HLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNF 433
           FA K       D   QL+ +L ++ P+VL+E GK KNP+PNVD  SGIL  +YG+ +  F
Sbjct: 370 FAEKRPKEFKSDAKVQLMKQLSQIAPKVLKEHGKTKNPYPNVDSASGILFYHYGIDQLLF 429

Query: 434 YTVLFGVSRALGTLSSLVWDRALGLPIERPKSVTTQWIRE 473
           +TV+FG SRA+G LS LVWDR LGLPIERPKS+    I++
Sbjct: 430 FTVIFGCSRAMGPLSQLVWDRILGLPIERPKSIDLNTIKK 469


ref|XP_512504.1| PREDICTED: similar to Citrate synthase, mitochondrial precursor [Pan troglodytes]
(1041 aa)

Score: 381 bits (978), Expect: 3.13146e-104
Length: 445, Idn/Pos/Gap = 201/280/61 (45%/62%/13%)

Query:  35 STSSATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYETSLL  94
           +++S+T+L++ +   I   +A++   R++ G++V+   TV+                   
Sbjct: 524 ASASSTNLKDILADLIPKEQARIKTFRQQHGKKVVGQITVDMI----------------- 566

Query:  95 DPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRR 154
                       +PECQ+LLP+AK  GE+PLPEGL WL +TG IPTE QV  + ++  +R
Sbjct: 567 ------------MPECQKLLPKAK-GGEEPLPEGLFWLPVTGRIPTEEQVSWLSKEWAKR 613

Query: 155 AAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDAL 214
           AA+P  V+ +LD  P   +HPM+Q S A++ L  ES  A+AYA+G  ++ +WE   ED++
Sbjct: 614 AALPSHVVTMLDNFP-TNLHPMSQLSAAITALNSESNFAQAYARGISRTKYWELIYEDSM 672

Query: 215 TLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVL 274
            LI +LP VAA+IYRN +  G    A  I+   D        LG+  ++F ELM LYL +
Sbjct: 673 DLITKLPCVAAKIYRNLYGEGSGTGA--IDSNLDWSHNFTNMLGYTDHQFPELMHLYLTI 730

Query: 275 HADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGN 334
           H+DHEGGNVSAH   LVGSALSDPYLSFAA +NGLAGPLHGLANQEVL WL Q+++++G 
Sbjct: 731 HSDHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPLHGLANQEVLVWLTQLQKEVG- 789

Query: 335 RPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSKL 394
           + ++ E LR+  W TL  G  +PG+GHA                           LV++L
Sbjct: 790 KDVSDEKLRDYIWNTLNSGRAVPGYGHA---------------------------LVAQL 822

Query: 395 YEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDR 454
            ++VP VL EQGK KNPWPNVD HSG+LL+YYG+ E N+YTVLFGVSRALG L+ L+W R
Sbjct: 823 CKIVPNVLLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLIWSR 882

Query: 455 ALGLPIERPKSVTTQWIREHFEKRS 479
           ALG P+ERPKS++T+ + +  + +S
Sbjct: 883 ALGFPLERPKSMSTEGLMKFVDSKS 907


emb|CAA35570.1| citrate synthetase [Arabidopsis thaliana]
(472 aa)

Score: 372 bits (954), Expect: 1.94795e-101
Length: 453, Idn/Pos/Gap = 210/274/12 (46%/60%/2%)

Query:  30 AVRALSTSSATSL--QEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAM  87
           +VR +   S+T L  +  ++  I   + ++ +++   G+  L   TV+   GGMR +  +
Sbjct:  27 SVRWIQMQSSTDLDLKSQLQELIPEHKDRLKKLKSEHGKVQLGNITVDMVIGGMRGMTGL  86

Query:  88 VYETSLLDPQEGIRFRGFSIPECQR-LLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVES 146
           ++ETSLLDP+E        +PECQ+ LLP A+  G        +  L       +S+++ 
Sbjct:  87 LWETSLLDPEEVFALGDCRLPECQKALLPTAQSGGLNHYRRSFVASLNWKGTLAKSKLKH 146

Query: 147 VCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFW 206
            C+    RAAV   V   +D LP    HPMTQF+  V  LQ +S+  +AY  G  KS FW
Sbjct: 147 -CRKTWNRAAVSDYVYNAIDALP-STAHPMTQFASGVMALQVQSEFQKAYENGIHKSKFW 204

Query: 207 EYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDE 266
           E   ED L LIAR+P VAA +YR  +  G  +P++K     D G   +  LGF+     E
Sbjct: 205 EPTYEDCLNLIARVPVVAAYVYRRMYKNGDSIPSDKSL---DYGANFSHMLGFDDERLKE 261

Query: 267 LMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLL 326
           LMRL       HEGGNVSAH   LVGSALSDPYLSFAA LNGLAGPLHGLANQEVL W+ 
Sbjct: 262 LMRLTSPSTVMHEGGNVSAHTGHLVGSALSDPYLSFAAALNGLAGPLHGLANQEVLLWIK 321

Query: 327 QMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDE 386
            + E+ G   ++ E L+E  W+TL  G VIPG+GH VLR TDPRY  QREFALKH P D 
Sbjct: 322 SVVEECG-EDISKEQLKEYVWKTLNSGKVIPGYGHGVLRNTDPRYVCQREFALKHHPDDP 380

Query: 387 MFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGT 446
           +FQ   KL ++   + E +   + PWPNVD HSG+LL +YGL E+ +YTVLFGVSR+LG 
Sbjct: 381 LFQ-CCKLMKLASCLTELES--EEPWPNVDAHSGVLLNHYGLTEARYYTVLFGVSRSLGI 437

Query: 447 LSSLVWDRALGLPIERPKSVTTQWIREHFEKRS 479
            S L+WDR L L +ERPKSVT  W+  H +K S
Sbjct: 438 CSQLIWDRELLLALERPKSVTMDWLEAHCKKAS 470


gb|AAP06106.1| similar to XM_053164 citrate synthase precursor in Homo sapiens [Schistosoma japonicum]
(376 aa)

Score: 371 bits (953), Expect: 2.50199e-101
Length: 366, Idn/Pos/Gap = 185/247/13 (50%/67%/3%)

Query:  28 KRAVRALSTSS--ATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLK  85
           +   R LS +S  + SL++ +   I   +A+V   R+ FG   +   TV+  YGGMR +K
Sbjct:  18 RNVFRQLSLTSVVSASLKDIMADLIPKEQAKVASFRKEFGTTKVGDVTVDMMYGGMRGIK  77

Query:  86 AMVYETSLLDPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVE 145
            +V ETS+LD  EGIRFRG SIP+CQ+ LP+A P G++PLPEG+ +LLLTG++PT++QV+
Sbjct:  78 GLVTETSVLDINEGIRFRGLSIPDCQKQLPKA-PGGQEPLPEGIFFLLLTGKVPTKAQVD 136

Query: 146 SVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTF 205
           ++ ++   RA +P  VL +LD  P   +HPM+Q   A + L  ESK A AY+QG  KS +
Sbjct: 137 NISKEFASRADLPSHVLNMLDSFP-SSLHPMSQLVAACAALNSESKFARAYSQGIKKSVY 195

Query: 206 WEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFD 265
           WEY  ED++ LIA+LP VA+ IYRN +  G  V A  I+   D      R LG+E   F 
Sbjct: 196 WEYVYEDSMDLIAKLPTVASIIYRNLYRDGTSVAA--IDSNTDWSHNFCRMLGYEDPGFT 253

Query: 266 ELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWL 325
           E+MRLYL  H DHEGGNVSAH+  LVGSALSDPYLSFAA + GLAGPLHGLANQEVL +L
Sbjct: 254 EMMRLYLTFHCDHEGGNVSAHSCHLVGSALSDPYLSFAASMCGLAGPLHGLANQEVLVFL 313

Query: 326 LQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHD 385
            +M+EK+G  P T EN+++   +TL  G VIPG+GHAVLR+TDPR+T  +EF        
Sbjct: 314 NKMQEKVGKNP-TDENVKQYVMDTLNSGQVIPGYGHAVLRKTDPRFTCAQEFV------K 366

Query: 386 EMFQLV 391
           + FQ++
Sbjct: 367 DTFQMI 372


emb|CAA95041.1| Cit3p [Saccharomyces cerevisiae]
emb|CAA88779.1| unknown [Saccharomyces cerevisiae]
emb|CAA61299.1| citrate (si)-synthase [Saccharomyces cerevisiae]
sp|P43635|CISY3_YEAST Citrate synthase 3
gb|AAA97580.1| Cit3p
ref|NP_015325.1| Cit3p [Saccharomyces cerevisiae]
(486 aa)

Score: 368 bits (945), Expect: 1.83797e-100
Length: 456, Idn/Pos/Gap = 202/280/22 (44%/61%/4%)

Query:  33 ALSTSSATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYETS  92
           A+  SSA +L+EA+ + I   R  V +++  +G   +   T++   GGMR  ++M ++ +
Sbjct:  20 AIIKSSALTLKEALENVIPKKRDAVKKLKACYGSTFVGPITISSVLGGMRGNQSMFWQGT  79

Query:  93 LLDPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLK 152
            LDP+ GI+F+G +I ECQ  LP     G+  LPE +LWLL+TG +PT  Q  S  ++L 
Sbjct:  80 SLDPEHGIKFQGLTIEECQNRLPNTGIDGDNFLPESMLWLLMTGGVPTFQQAASFRKELA 139

Query: 153 RRA-AVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQG-APKSTFWEYCL 210
            R   +P    ++L  LP + MHPMTQ ++ ++ +   S  A  Y +G   K  FW+  L
Sbjct: 140 IRGRKLPHYTEKVLSSLPKD-MHPMTQLAIGLASMNKGSLFATNYQKGLIGKMEFWKDTL 198

Query: 211 EDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVD-------DMGMRLARSLGFELN- 262
           ED+L LIA LP +  RIY N  + G H   +  E+VD        +GM    +     N 
Sbjct: 199 EDSLNLIASLPLLTGRIYSNITNEG-HPLGQYSEEVDWCTNICSLLGMTNGTNSSNTCNL 257

Query: 263 ------EFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGL 316
                 +F  LMRLY  +H DHEGGNVSAH   LVGSALSDPYLS+++G+ GLAGPLHGL
Sbjct: 258 TSQQSLDFINLMRLYTGIHVDHEGGNVSAHTTHLVGSALSDPYLSYSSGIMGLAGPLHGL 317

Query: 317 ANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQRE 376
           A QEV+R+L++M   + +     E +++  W+ L    VIPG+GHAVLR+ DPR+TA  E
Sbjct: 318 AAQEVVRFLIEMNSNISSIAREQE-IKDYLWKILNSNRVIPGYGHAVLRKPDPRFTAMLE 376

Query: 377 FALK---HLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNF 433
           FA K      +D+   L+ KL E+ P+VL E GK KNP+PNVD  SGIL  +YG+ E  F
Sbjct: 377 FAQKRPIEFENDKNVLLMQKLAEIAPKVLLEHGKSKNPFPNVDSASGILFYHYGIRELLF 436

Query: 434 YTVLFGVSRALGTLSSLVWDRALGLPIERPKSVTTQ 469
           +TV+FG SRA+G L+ LVWDR LGLPIERPKS+  +
Sbjct: 437 FTVIFGCSRAMGPLTQLVWDRILGLPIERPKSLNLE 472


gb|AAL39405.1| GM05016p [Drosophila melanogaster]
(261 aa)

Score: 367 bits (943), Expect: 3.32366e-100
Length: 264, Idn/Pos/Gap = 176/210/3 (66%/79%/1%)

Query: 214 LTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLV 273
           + LIA+LP VAA IY NT+ GGK   +  I+   D      + LG++   F ELMRLYL 
Sbjct:   1 MDLIAKLPVVAATIYCNTYRGGKG--SRSIDSSLDWSANFVKMLGYDNAPFTELMRLYLT  58

Query: 274 LHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLG 333
           +H+DHEGGNVSAH V LVGSALSDPYLSFAAGLNGLAGPLHGLANQEVL WL +++++ G
Sbjct:  59 IHSDHEGGNVSAHTVHLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLVWLRKLQKEAG 118

Query: 334 NRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSK 393
           N P + E L+E  W+TL+ G V+PG+GHAVLR+TDPRYT QREFALKHLP DE FQLVSK
Sbjct: 119 NNP-SEEQLKEYIWKTLKSGQVVPGYGHAVLRKTDPRYTCQREFALKHLPEDETFQLVSK 177

Query: 394 LYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWD 453
           +Y+VVP +L E GKVKNPWPNVD HSG+LL+YYG+ E N+YTVLFGVSRALG L+SLVWD
Sbjct: 178 IYKVVPPILTETGKVKNPWPNVDAHSGVLLQYYGMKEMNYYTVLFGVSRALGVLASLVWD 237

Query: 454 RALGLPIERPKSVTTQWIREHFEK 477
           RALGLPIERPKS +T  + +  +K
Sbjct: 238 RALGLPIERPKSFSTDLLVKMVQK 261


emb|CAG62140.1| unnamed protein product [Candida glabrata CBS138]
ref|XP_449170.1| unnamed protein product [Candida glabrata]
(480 aa)

Score: 363 bits (932), Expect: 5.81469e-99
Length: 459, Idn/Pos/Gap = 190/282/29 (41%/61%/6%)

Query:  32 RALSTSSATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYET  91
           R LS+S+A+SL++ ++  I   R +  ++++ + +  +   T+    GGMR  ++M ++ 
Sbjct:  16 RILSSSTASSLKQRLKEVIPDKREKFTKIKKNYSDVKVGDITIGSVIGGMRGNQSMFWQG  75

Query:  92 SLLDPQEGIRFRGFSIPECQRLLP---RAKPSGEQPLPEGLLWLLLTGEIPTESQVESVC 148
           + LDP+EGIRF+G SIPEC   +          +  LPE +LWLL+TGE+PT+ Q  S+ 
Sbjct:  76 TSLDPEEGIRFQGLSIPECMDQMAGISEIHGGSKSLLPESMLWLLMTGELPTKEQTNSLS 135

Query: 149 QDLKRRAAVPPE-VLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGA-PKSTFW 206
           ++L  R  + P+ V  ++  LP + MHPMTQ ++ ++ L   S+ A+ Y +G+  K+ +W
Sbjct: 136 KELAERGKILPQSVNTIVSNLPKD-MHPMTQLAIGLASLNQYSQFAKEYEKGSIGKNDYW 194

Query: 207 EYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGF------- 259
           ++  ED L LIA LP +  +IY N  + GK  P  +  +  D    ++  LG        
Sbjct: 195 DFIYEDVLNLIASLPHLTGQIYANITNEGK--PLGEFNENADWAYNISSLLGMTTEASSA 252

Query: 260 --------ELNEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAG 311
                      +F +L+RLY  +H DHEGGNVSAHA  LVGSAL DP++S+A+G+ GLAG
Sbjct: 253 NKQNLSEKRAQDFADLVRLYTAIHVDHEGGNVSAHATHLVGSALGDPFISYASGIMGLAG 312

Query: 312 PLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRY 371
           PLHGLA QEV+R+L++M   + + P     +    W  L    V+PG+GHAVLR+ DPR+
Sbjct: 313 PLHGLAAQEVVRFLVEMNASISS-PENVPEIENYLWSILNSRRVVPGYGHAVLRKPDPRF 371

Query: 372 TAQREFALKHLP----HDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYG 427
            A   FA K  P     D+   L+  L  + P+VL+E GK KNP+PNVD  SGIL  +YG
Sbjct: 372 NAMLNFA-KERPDEFQSDKNVLLMENLSTIAPKVLQEHGKCKNPFPNVDSASGILFHHYG 430

Query: 428 LVESNFYTVLFGVSRALGTLSSLVWDRALGLPIERPKSV 466
           + E+ F+TV+FG SRA+G+L+ LVWDR LGLPIERP+S+
Sbjct: 431 IQETLFFTVIFGCSRAIGSLTQLVWDRILGLPIERPRSL 469


gb|AAS54491.1| AGR002Wp [Ashbya gossypii ATCC 10895]
ref|NP_986667.1| AGR002Wp [Eremothecium gossypii]
(482 aa)

Score: 360 bits (923), Expect: 6.11497e-98
Length: 468, Idn/Pos/Gap = 203/280/31 (43%/59%/6%)

Query:  29 RAVRALSTSSATSLQEAVRSKIEPMRAQVHEVRE--RFGEEVLDACTVNQAYGGMRSLKA  86
           R++   ST+   SL+EAV   I P+R   HE++E   +    +D+ TV    GGMR+ K+
Sbjct:  11 RSITRSSTARPRSLKEAVEQAI-PLRR--HELKELKAYSNMQIDSITVGSIIGGMRNNKS  67

Query:  87 MVYETSLLDPQEGIRFRGFSIPECQRLLPRA---KPSGEQPLPEGLLWLLLTGEIPTESQ 143
           M+++ + LDP  GI+F+G +I ECQ+LLP +   +    + +PE +LWLL+TGEIP + +
Sbjct:  68 MLWQGTTLDPFNGIKFQGKTIQECQQLLPCSPDKQSKKTEFMPESMLWLLMTGEIPKKEE 127

Query: 144 VESVCQDLKRRA-AVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGA-P 201
              +  +L +R   +PP V  ++D LP   MHPMTQ +VA++ L   S   + Y  G   
Sbjct: 128 AFGLMHELSQRGKTLPPFVEHIIDSLPRT-MHPMTQLAVALASLNSSSTFCKNYQDGVIG 186

Query: 202 KSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGF-- 259
           K  +W Y  EDAL LIA LP +  +IY N  + G  +P        D    +A  LG   
Sbjct: 187 KEDYWHYIFEDALNLIALLPQLVGKIYSNVTNEG--MPLGYFNPDRDWSYNIASLLGMTY 244

Query: 260 ------------ELNEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLN 307
                       + ++F +L+RLY  +H DHEGGNVSAHA  LVGSALSDPYLS++AG+ 
Sbjct: 245 RDSVNKRNLTKEQCDDFTDLVRLYCGIHVDHEGGNVSAHATHLVGSALSDPYLSYSAGVM 304

Query: 308 GLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRT 367
           GLAGPLHGLA QEV+R+L+ M  ++ + P     + E  W  L  G V+PG+GHAVLR+ 
Sbjct: 305 GLAGPLHGLAAQEVVRFLVDMAARI-DSPDNESQVSEYLWALLNSGKVVPGYGHAVLRKP 363

Query: 368 DPRYTAQREFAL---KHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLR 424
           DPR+ A   F     +    D   QL+  L +  P+VL E GK KNP+PNVD  SG+L  
Sbjct: 364 DPRFDAMLRFVEARPQEFQGDRYVQLMRNLSKYAPKVLTEHGKTKNPFPNVDSASGVLFY 423

Query: 425 YYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLPIERPKSVTTQWIR 472
           +YG+ +  F TV+F  SRA+G L+ LVWDR LGLPIERPKSV    +R
Sbjct: 424 HYGIHDLLFVTVIFACSRAIGPLTQLVWDRILGLPIERPKSVDMATLR 471


ref|NP_700691.1| citrate synthase, mitochondrial precursor, putative [Plasmodium falciparum 3D7]
gb|AAN35415.1| citrate synthase, mitochondrial precursor, putative [Plasmodium falciparum 3D7]
(563 aa)

Score: 353 bits (906), Expect: 7.29025e-96
Length: 442, Idn/Pos/Gap = 178/268/4 (40%/60%/0%)

Query:  42 LQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYETSLLDPQEGIR 101
           L+E     I+  R Q+ E+   +    +  CT N   GG+R+   ++ +TS+L+ ++GI 
Sbjct: 117 LKEKTYECIKKTREQLKEIIHTYPNTPISICTPNNVIGGLRNTITLITDTSILEKKKGIL 176

Query: 102 FRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAA-VPPE 160
           FRG  + +  R  P+   + E P+ E +LW LLT E+P    ++ + ++L  RA  +P  
Sbjct: 177 FRGKPVEKILREFPKWDNTCEYPMAEAMLWFLLTKEVPAVDDLKLLSRELYCRAKKIPQF 236

Query: 161 VLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARL 220
           V   +D +P    HPM+Q    VS L+  S     Y++G  K+ +W+Y LEDA++LI+++
Sbjct: 237 VFDFIDNIP-PFTHPMSQLVSTVSFLESLSLFKYKYSEGILKTDYWKYILEDAISLISQI 295

Query: 221 PAVAARIYRNTFHGGKHVPAEKIE-KVD-DMGMRLARSLGFELNEFDELMRLYLVLHADH 278
             + A I++ TF        E +   +D D     A+ +G+E  E  +L+RLY +LH+DH
Sbjct: 296 QVIGAYIFKRTFINNDIRKGEGMNLDLDLDWSANFAKLIGYENKEVQDLLRLYFLLHSDH 355

Query: 279 EGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMT 338
           EGGN SAH   L+GS L +PYLS++  +  L+GPLHGLANQE L++LL +K++LG+  +T
Sbjct: 356 EGGNASAHVSHLIGSTLGNPYLSYSGCVIALSGPLHGLANQECLKFLLDIKKQLGDNQLT 415

Query: 339 TENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSKLYEVV 398
            E + +     L+ G VIPG+GHAVLR  DPR+ A R FAL H P D + Q++   Y+V+
Sbjct: 416 YEFIEKYAKNLLKSGRVIPGYGHAVLRVPDPRFLALRSFALSHFPDDPIIQILEMCYKVI 475

Query: 399 PRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGL 458
           P +L   GKVKNP+PNVD  SG +L +YG+    +YTVLF +SR++G +S LV  R L  
Sbjct: 476 PGILSATGKVKNPYPNVDCSSGSVLHHYGIKYPEYYTVLFALSRSIGVMSQLVLSRGLMY 535

Query: 459 PIERPKSVTTQWIREHFEKRSV 480
           P+ERPKSV    +R+  EK  V
Sbjct: 536 PLERPKSVDIYNLRKICEKNYV 557


gb|AAO32483.1| CIT3 [Saccharomyces castellii]
(473 aa)

Score: 352 bits (904), Expect: 1.25395e-95
Length: 458, Idn/Pos/Gap = 189/274/28 (41%/59%/6%)

Query:  37 SSATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYETSLLDP  96
           S AT L+E++++ I   + +  ++++      +D  T+     GMR  ++M +E S++D 
Sbjct:  16 SQATGLKESLKAIIPKRKEEFLKLKKECMGTKVDDITIGSILSGMRGNRSMFWEGSMVDA  75

Query:  97 QEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRR-- 154
           Q GI F G +I +CQR LP    SG    PE +LWLL+TGE+PT+ Q + + ++L  R  
Sbjct:  76 QRGITFHGKTIEQCQRELP-GDESGNF-YPESMLWLLMTGEVPTKQQTKQLMEELAVRGS 133

Query: 155 -AAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGA-PKSTFWEYCLED 212
            A  P    R++D LP++ MHPMTQ ++ ++ +   S+ A  Y +G   K+ +WE   ED
Sbjct: 134 EANFPIATSRVIDSLPND-MHPMTQLAIGLASMNKVSRFASNYEKGLLNKNNYWEDTFED 192

Query: 213 ALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGF------------- 259
            L LI+ LP +  +IY    + GK  P  K    +D    +   +G              
Sbjct: 193 TLNLISFLPILTGKIYSKITNDGK--PLGKFSPTEDWSSNICSLMGMSNSTYSVNKNNFN 250

Query: 260 --ELNEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLA 317
             E  +F  LMRLY  +HADHEGGNVSAH   LVGSALSDPYLS+++G+ GLAGPLHGLA
Sbjct: 251 ASESKDFLSLMRLYTGIHADHEGGNVSAHTTHLVGSALSDPYLSYSSGIMGLAGPLHGLA 310

Query: 318 NQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREF 377
            QEV+R+L++M  ++ + P   + +    W+ L    VIPG+GHA LR+ DPR+TA  +F
Sbjct: 311 AQEVVRFLVEMNGQISS-PNQPDEIERYLWDLLNSKRVIPGYGHATLRKPDPRFTAMLKF 369

Query: 378 A---LKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFY 434
                    +D+   L+  L  + P+VL+  GK +NP+PNVD  SGIL  +YGL ES F+
Sbjct: 370 TKDRKSEFENDKNVVLMQNLSSIAPKVLKAHGKCQNPYPNVDSASGILFHHYGLKESLFF 429

Query: 435 TVLFGVSRALGTLSSLVWDRALGLPIERPKSVTTQWIR 472
           TV+FG SR++G L+ LVWDR  GLPIERPKSV  + ++
Sbjct: 430 TVIFGCSRSMGPLTQLVWDRIYGLPIERPKSVNMETLK 467


gb|AAP36082.1| citrate synthase [Homo sapiens]
(264 aa)

Score: 350 bits (899), Expect: 4.31101e-95
Length: 266, Idn/Pos/Gap = 163/207/3 (61%/77%/1%)

Query: 214 LTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLV 273
           + LIA+LP VAA+IYRN +  G  + A  I+   D        LG+  ++F EL RLYL 
Sbjct:   1 MDLIAKLPCVAAKIYRNLYREGSGIGA--IDSNLDWSHNFTNMLGYTDHQFTELTRLYLT  58

Query: 274 LHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLG 333
           +H+DHEGGNVSAH   LVGSALSDPYLSFAA +NGLAGPLHGLANQEVL WL Q+++++G
Sbjct:  59 IHSDHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPLHGLANQEVLVWLTQLQKEVG 118

Query: 334 NRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSK 393
            + ++ E LR+  W TL  G V+PG+GHAVLR+TDPRYT QREFALKHLP+D MF+LV++
Sbjct: 119 -KDVSDEKLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYTCQREFALKHLPNDPMFKLVAQ 177

Query: 394 LYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWD 453
           LY++VP VL EQGK KNPWPNVD HSG+LL+YYG+ E N+YTVLFGVSRALG L+ L+W 
Sbjct: 178 LYKIVPNVLLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLIWS 237

Query: 454 RALGLPIERPKSVTTQWIREHFEKRS 479
           RALG P+ERPKS++T+ + +  + +S
Sbjct: 238 RALGFPLERPKSMSTEGLMKFVDSKS 263


gb|EAA21017.1| probable citrate synthase, mitochondrial precursor [Plasmodium yoelii yoelii]
(566 aa)

Score: 348 bits (893), Expect: 2.34519e-94
Length: 442, Idn/Pos/Gap = 180/265/4 (40%/59%/0%)

Query:  42 LQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYETSLLDPQEGIR 101
           L+E   + I+  R Q+  +   +    +  CT N   GG+R+   ++ +TS+L+ ++GI 
Sbjct: 120 LKEKTHACIKKTREQLKTIIHTYPNTPISICTPNNVIGGLRNTITLITDTSILEKKKGIL 179

Query: 102 FRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRA-AVPPE 160
           FRG S+ +  +  P+   + + P+ E +LW LLT EIP    ++   ++L  RA  +P  
Sbjct: 180 FRGRSVDKILKDFPKWDETCKYPMAEAMLWYLLTKEIPGVENLKLFSRELYCRANKIPSF 239

Query: 161 VLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARL 220
           V   +D +P    HPM+Q    VS L+  S     Y++G  KS +W+Y LEDA++LIA++
Sbjct: 240 VFEFIDNIP-PFTHPMSQLISTVSFLESLSLFKIKYSEGILKSDYWKYILEDAVSLIAQI 298

Query: 221 PAVAARIYRNTFHGGKHVPAEKIE-KVD-DMGMRLARSLGFELNEFDELMRLYLVLHADH 278
             V A I+R TF        E I   +D D     ++ +G++ N+  +L+RLY +LH+DH
Sbjct: 299 QVVGAYIFRRTFIDNSIKKGEGINLDIDLDWSANFSKLIGYDSNQVKDLLRLYFLLHSDH 358

Query: 279 EGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMT 338
           EGGN SAH   L+GS L +PYLSF+     L GPLHGLANQE L +LL +K KLG+   +
Sbjct: 359 EGGNASAHVSHLIGSTLGNPYLSFSGCAIALYGPLHGLANQECLNFLLDIKNKLGDNKAS 418

Query: 339 TENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSKLYEVV 398
            E + +     L  G VIPG+GHAVLR  DPR+ A R FAL + P+D + +++   Y+V+
Sbjct: 419 YEFIEKYAKNYLNSGRVIPGYGHAVLRVPDPRFLAFRNFALANFPNDPLVEILEMCYKVI 478

Query: 399 PRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGL 458
           P +L   GKVKNP+PNVD +SG LL +YG+    +YTVLF +SRA+G +S LV  R L  
Sbjct: 479 PGILSATGKVKNPYPNVDCYSGSLLYHYGIKYPEYYTVLFAISRAIGVMSQLVLSRGLMY 538

Query: 459 PIERPKSVTTQWIREHFEKRSV 480
           P+ERP+SV    +R+  EK  V
Sbjct: 539 PLERPRSVDVYNLRKICEKNYV 560


emb|CAH98955.1| citrate synthase, mitochondrial precursor, putative [Plasmodium berghei]
(566 aa)

Score: 346 bits (888), Expect: 8.98639e-94
Length: 442, Idn/Pos/Gap = 180/263/4 (40%/59%/0%)

Query:  42 LQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYETSLLDPQEGIR 101
           L+E     I+  R Q+  +   +    +  CT N   GG+R+  A++ +TS+L+ ++GI 
Sbjct: 120 LKEKTHDCIKKTREQLKTIIYTYPNTPISICTPNNVIGGLRNTIALITDTSILEKKKGIL 179

Query: 102 FRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRA-AVPPE 160
           FRG S+    +  P+   + + P+ E +LW LLT EIP    ++   ++L  RA  +P  
Sbjct: 180 FRGRSVDRILKDFPKWDETCKYPMAEAMLWYLLTKEIPGVENLKLFSRELYCRANKIPQF 239

Query: 161 VLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARL 220
           V   +D +P    HPM+Q    VS L+  S     Y++G  K  +W+Y LEDA++LIA++
Sbjct: 240 VFEFIDSIP-PFTHPMSQLISTVSFLESLSLFKIKYSEGILKKDYWKYILEDAVSLIAQI 298

Query: 221 PAVAARIYRNTFHGGKHVPAEKIE-KVD-DMGMRLARSLGFELNEFDELMRLYLVLHADH 278
             V A I++ TF        E I   +D D     ++ +G++ N+  +L+RLY +LH+DH
Sbjct: 299 QVVGAYIFKRTFIDNSIKKGEGINLDIDLDWSANFSKLIGYDNNQVKDLLRLYFLLHSDH 358

Query: 279 EGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMT 338
           EGGN SAH   L+GS L +PYLSF+     L GPLHGLANQE L++LL +K KLG+   +
Sbjct: 359 EGGNASAHVSHLIGSTLGNPYLSFSGCAIALYGPLHGLANQECLKFLLDIKNKLGDNKAS 418

Query: 339 TENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSKLYEVV 398
            E + +     L  G VIPG+GHAVLR  DPR+ A R FAL + P D + +++   Y+V+
Sbjct: 419 YEFIEKYAKNYLNSGRVIPGYGHAVLRVPDPRFLAFRNFALANFPDDPLVEILEMCYKVI 478

Query: 399 PRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGL 458
           P +L   GKVKNP+PNVD +SG LL +YG+    +YTVLF +SRA+G +S LV  R L  
Sbjct: 479 PGILSAAGKVKNPYPNVDCYSGSLLYHYGIKYPEYYTVLFAISRAIGVMSQLVLSRGLMY 538

Query: 459 PIERPKSVTTQWIREHFEKRSV 480
           P+ERPKSV    +R+  EK  V
Sbjct: 539 PLERPKSVDIHNLRKICEKNYV 560


gb|AAS67344.1| citrate synthase [Malonomonas rubra]
(292 aa)

Score: 281 bits (719), Expect: 2.8818e-74
Length: 305, Idn/Pos/Gap = 152/194/20 (49%/63%/6%)

Query: 128 GLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQ 187
           G  +LLLTG++PT  Q   V +D  +R+AVP  V+ +L  LP +  HPM  FS A+  +Q
Sbjct:   1 GFWYLLLTGDVPTMEQTLEVVEDWNQRSAVPEYVIDVLRALPRDS-HPMAMFSAAIVAMQ  59

Query: 188 HESKMAEAYAQGA-PKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHV-PAEKIEK 245
            ES  A  YA G   K T WE   EDA TL+ARL  + A IYR  + G  H+ P  ++  
Sbjct:  60 RESVFASNYAAGKFNKMTCWEDMYEDANTLMARLGPIGAYIYRMKYKGDTHIAPDPEL-- 117

Query: 246 VDDMGMRLARSLGFELNEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAG 305
             DMG + A  +G + +E+ ++ R+Y +LH+DHE GNVSAH   LV SALSD Y +++AG
Sbjct: 118 --DMGGQFAHMIG-QSDEYKDVARMYFILHSDHESGNVSAHTTHLVASALSDAYYAYSAG 174

Query: 306 LNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLR 365
           +NGLAGPLHGLAN+EVLRW     +KLG    T E L+E  W TL  G VIPG+GHAVLR
Sbjct: 175 INGLAGPLHGLANEEVLRWTQNFMQKLGGEVPTEEGLKEALWATLNSGQVIPGYGHAVLR 234

Query: 366 RTDPRYTAQREF-----ALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSG 420
           +TDPRYT+QREF      LK  P   +FQLV  ++EV P VL E    KNPWPNVD  SG
Sbjct: 235 KTDPRYTSQREFCMNTSGLKEYP---LFQLVKMIFEVAPGVLTE----KNPWPNVDAQSG 287

Query: 421 ILLRY 425
           ++  Y
Sbjct: 288 VIQWY 292


gb|AAO32559.1| CIT3 [Saccharomyces kluyveri]
(332 aa)

Score: 279 bits (713), Expect: 1.7328e-73
Length: 323, Idn/Pos/Gap = 145/198/22 (44%/61%/6%)

Query: 168 LPHERMHPMTQFSVAVSLLQHESKMAEAYAQGA-PKSTFWEYCLEDALTLIARLPAVAAR 226
           LP + MHP  Q ++ ++ +   S  +  Y +G   K  +WE+  EDAL LI+ LP +  +
Sbjct:  10 LPKD-MHPNLQLAIGLASMNKSSLFSAMYQEGTIGKGDYWEFVYEDALNLISALPLLTGK  68

Query: 227 IYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGF--------------ELNEFDELMRLYL 272
           IY N  + G+  P  +     D    +A  LG               +  +F  L+RLY 
Sbjct:  69 IYSNIVNDGE--PLGQFNPDRDWSYNIASLLGMTFRDSVNKQHMTADQCEDFTNLVRLYC 126

Query: 273 VLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKL 332
            +H DHEGGNVSAH   LVGSALSDPYLS+++G+ GLAGPLHGLA QEV+R+L++M  ++
Sbjct: 127 GIHVDHEGGNVSAHTTHLVGSALSDPYLSYSSGIMGLAGPLHGLAAQEVVRFLVEMNSEI 186

Query: 333 GNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFA---LKHLPHDEMFQ 389
              P   + + E  W+ L+   VIPG+GHAVLR+ DPR+ A   F     +    D+  Q
Sbjct: 187 -ESPENEKQVEEYLWKILKSNRVIPGYGHAVLRKPDPRFEAMLRFVEDRQQEFAQDKNVQ 245

Query: 390 LVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSS 449
           L+ K+ +V P+VL + GK KNP+PNVD  SGIL  +YG+ E  F+TV+FG SR++G L+ 
Sbjct: 246 LMKKMSQVAPKVLAKHGKTKNPFPNVDSASGILFHHYGIQELLFFTVIFGCSRSIGPLTQ 305

Query: 450 LVWDRALGLPIERPKSVTTQWIR 472
           LVWDRALGLPIERPKSV    IR
Sbjct: 306 LVWDRALGLPIERPKSVDLNTIR 328


gb|AAS67342.1| citrate synthase [Geobacter bemidjiensis]
(300 aa)

Score: 275 bits (704), Expect: 1.66248e-72
Length: 301, Idn/Pos/Gap = 145/192/9 (48%/63%/2%)

Query: 114 LPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERM 173
           LP+A  S E P  E   + LLTGE+PT +QV +V  + K R  VP  V   +  LP E  
Sbjct:   6 LPKAAGS-EYPTVESFWYFLLTGEVPTAAQVSAVEAEFKTRQVVPEYVYTAVRALPKES-  63

Query: 174 HPMTQFSVAVSLLQHESKMAEAYAQGA-PKSTFWEYCLEDALTLIARLPAVAARIYRNTF 232
           HPM   SV +  +Q +SK A  Y+ G   K   WE   EDA  ++AR+P +AA IY   +
Sbjct:  64 HPMVMLSVGIMAMQKDSKFAAFYSGGKFNKMDAWESVYEDASDIVARIPVLAAFIYNLKY 123

Query: 233 HGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVLHADHEGGNVSAHAVRLVG 292
            G K +    I+   DMG   A  +G +  ++ ++ R+Y +LH+DHE GNVSAH   LV 
Sbjct: 124 RGDKQI---AIDPKLDMGANFAHMIG-QSEQYKDVARMYFILHSDHESGNVSAHTTHLVH 179

Query: 293 SALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLRE 352
           SALSDPY +++AGLNGLAGPLHGLANQEVL W+++ ++KL     T EN+ +  W+TL  
Sbjct: 180 SALSDPYYAYSAGLNGLAGPLHGLANQEVLGWIMEFQKKLNGAEPTKENVTKALWDTLNA 239

Query: 353 GHVIPGFGHAVLRRTDPRYTAQREFALKH--LPHDEMFQLVSKLYEVVPRVLEEQGKVKN 410
           G V+PG+GHAVLR+TDPRYTAQREF LK   L  D++F+LV+ ++E  P VL E GK KN
Sbjct: 240 GQVVPGYGHAVLRKTDPRYTAQREFCLKTPGLKDDQLFKLVAMIFETAPGVLTEHGKTKN 299

Query: 411 P 411
           P
Sbjct: 300 P 300


gb|AAO32375.1| CIT2 [Saccharomyces bayanus]
(294 aa)

Score: 271 bits (694), Expect: 2.69807e-71
Length: 272, Idn/Pos/Gap = 143/185/12 (52%/68%/4%)

Query:  48 SKIEPMRAQ-VHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYETSLLDPQEGIRFRGFS 106
           S+I P  AQ V +  +  G+  +    + Q YGGMR +   V+E S LD +EGIRFRG +
Sbjct:  31 SEIYPSHAQDVKQFVKEHGKTKISDVLLEQVYGGMRGVPGSVWEGSELDAEEGIRFRGRT  90

Query: 107 IPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLD 166
           I + Q+ LP+AK S  QPLPE L WLLLTGE+PT++QVE++  DL  R+ +P  V++LLD
Sbjct:  91 IADIQKELPKAKGS-SQPLPEALFWLLLTGEVPTQAQVENLSADLMSRSELPHHVVQLLD 149

Query: 167 ELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAAR 226
            LP + +HPM Q S+AV+ L+ ESK A+AYAQG  K  +W Y  ED+L L+ +LP +AA+
Sbjct: 150 NLPKD-LHPMAQLSIAVTALESESKFAKAYAQGISKQDYWSYTFEDSLDLLGKLPVIAAK 208

Query: 227 IYRNTFHGGKHVPAEKIEKVD---DMGMRLARSLGFELNEFDELMRLYLVLHADHEGGNV 283
           IYRN F  GK      I +VD   D G  L   +G +  +F +LMRLYL +H+DHEGGNV
Sbjct: 209 IYRNVFKDGK------IGEVDPNADYGKNLVNLIGSKDEDFVDLMRLYLTIHSDHEGGNV 262

Query: 284 SAHAVRLVGSALSDPYLSFAAGLNGLAGPLHG 315
           SAH   LVGSALS PYLS A+GLNGLAGPLHG
Sbjct: 263 SAHTSHLVGSALSSPYLSLASGLNGLAGPLHG 294


gb|AAS67343.1| citrate synthase [Desulfuromonas acetexigens]
(299 aa)

Score: 270 bits (690), Expect: 7.34328e-71
Length: 305, Idn/Pos/Gap = 145/190/10 (47%/62%/3%)

Query: 116 RAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHP 175
           +AK S + P  E   + LLTG++PT++QV++V  + K R  VP  V   +  LP +  HP
Sbjct:   1 KAKGS-KYPTVESFWYFLLTGDVPTQAQVDAVVAEWKTRQIVPSYVWDAIRALPRDS-HP  58

Query: 176 MTQFSVAVSLLQHESKMAEAYAQGA-PKSTFWEYCLEDALTLIARLPAVAARIYRNTFHG 234
           M   SV +  LQ +SK A  Y  G   K T WE   EDA  L AR+P +AA IY   +  
Sbjct:  59 MVMLSVGILALQKDSKFAAFYNSGKFNKMTAWESVYEDASDLCARIPIIAAFIYNLKYRS 118

Query: 235 GKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVLHADHEGGNVSAHAVRLVGSA 294
                   I+   DMG   A  +G +  E+ ++ R+Y +LH+DHE GNVSAH   LV SA
Sbjct: 119 DFQT---AIDPNLDMGANFAHMIG-QCEEYKDVARMYFILHSDHESGNVSAHTTHLVHSA 174

Query: 295 LSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKL-GNRPMTTENLRELCWETLREG 353
           LSDPY +++AGLNGLAGPLHGLANQEVL W L+ +EK   +   T E + +  W+TL  G
Sbjct: 175 LSDPYYAYSAGLNGLAGPLHGLANQEVLDWTLKFQEKYCKDVEPTKELVTKALWDTLNAG 234

Query: 354 HVIPGFGHAVLRRTDPRYTAQREFALKH--LPHDEMFQLVSKLYEVVPRVLEEQGKVKNP 411
            V+PG+GHAVLR+TDPRY +QREF L    L  D++F+LV+ ++E  P VL E GK KNP
Sbjct: 235 QVVPGYGHAVLRKTDPRYMSQREFCLNTPGLKDDKLFKLVAMIFETAPGVLTEHGKAKNP 294

Query: 412 WPNVD 416
           WPNVD
Sbjct: 295 WPNVD 299


emb|CAH86617.1| citrate synthase, mitochondrial precursor, putative [Plasmodium chabaudi]
(350 aa)

Score: 217 bits (552), Expect: 7.75615e-55
Length: 302, Idn/Pos/Gap = 114/175/4 (37%/57%/1%)

Query:  42 LQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYETSLLDPQEGIR 101
           L+E     IE  R Q+  +   +    +  CT N   GG+R+   ++ +TS+L+ ++GI 
Sbjct:  45 LKEKTHDCIEKTREQLKTIIHTYPNTPISICTPNNVIGGLRNTITLITDTSILEKKKGIL 104

Query: 102 FRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAA-VPPE 160
           FRG S+ +  +  P+   + + P+ E +LW LLT EIP    ++   ++L  RA  +PP 
Sbjct: 105 FRGRSVDKILKDFPKWDETCKYPMAEAMLWYLLTKEIPGVENLKLFSRELYCRAKKIPPF 164

Query: 161 VLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARL 220
           V   +D +P    HPM+Q    VS L+  S     Y++G  K  +W+Y LEDA++LIA++
Sbjct: 165 VFEFIDSIP-PFTHPMSQLISTVSFLESLSIFKIKYSEGILKKDYWKYILEDAVSLIAQI 223

Query: 221 PAVAARIYRNTFHGGKHVPAEKIE-KVD-DMGMRLARSLGFELNEFDELMRLYLVLHADH 278
             V A I++ TF        E I+  +D D     ++ +G++ N+  +L+RLY +LH+DH
Sbjct: 224 QVVGAYIFKRTFIDNSIKNGEGIDLDIDLDWSANFSKMIGYDSNQVKDLLRLYFLLHSDH 283

Query: 279 EGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMT 338
           EGGN SAH   L+GS L +PYLSF+     L GPLHGLANQE L++LL +K KLG+   +
Sbjct: 284 EGGNASAHVSHLIGSTLGNPYLSFSGCAIALYGPLHGLANQECLKFLLDIKNKLGDNKAS 343

Query: 339 TE 340
            E
Sbjct: 344 YE 345


dbj|BAC16330.1| citrate synthase [Sesbania rostrata]
(188 aa)

Score: 196 bits (497), Expect: 1.80464e-48
Length: 186, Idn/Pos/Gap = 97/125/3 (52%/67%/1%)

Query: 182 AVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAE 241
            V  LQ +S+  +AY  G  KS +WE   ED++ LIARLPA+AA IYR  +  GK +P  
Sbjct:   2 GVMALQVQSEFQKAYEGGITKSRYWEPTYEDSMNLIARLPAIAAYIYRRKYKDGKIIP--  59

Query: 242 KIEKVDDMGMRLARSLGFELNEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLS 301
            ++   D G   A  LGF+  E  E MRLY+ +H+DHEGGNVS+H   LV S LSDPYL+
Sbjct:  60 -LDDSLDYGANYAHMLGFDDPEMLEFMRLYVSIHSDHEGGNVSSHTAHLVASPLSDPYLA 118

Query: 302 FAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGH 361
           FAA LNGLAGPLHGLANQEVLRW+  + ++ G   ++TE L +   +TL  G V+PG+GH
Sbjct: 119 FAAALNGLAGPLHGLANQEVLRWIRSIVKEFGTPNISTEQLSDYIHKTLSSGQVVPGYGH 178

Query: 362 AVLRRT 367
            VLR+T
Sbjct: 179 GVLRKT 184


ref|XP_533022.1| PREDICTED: similar to citrate (si)-synthase (EC 4.1.3.7) precursor - pig [Canis familiaris]
(219 aa)

Score: 191 bits (484), Expect: 5.16529e-47
Length: 198, Idn/Pos/Gap = 91/137/4 (45%/69%/2%)

Query:  35 STSSATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYETSLL  94
           +++S+T+L++ +   I   +A++   R++ G+ V+D  TV+  YGGMR +K +VYETS+L
Sbjct:  26 ASASSTNLKDILADLIPKAQARIKTFRQQHGKTVVDQITVDMMYGGMRGMKGLVYETSVL  85

Query:  95 DPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRR 154
           DP E I FRG+SIPECQ+LL +AK  GE+PLPEGL WLL+T +IPTE QV  + ++  +R
Sbjct:  86 DPDEDIHFRGYSIPECQKLLLKAK-GGEEPLPEGLFWLLVTRQIPTEEQVSWLSKEWAKR 144

Query: 155 AAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDAL 214
           AA+P  V+ +LD  P   +HPM+Q S A++ L  ES  A   A+G  ++ +WE   ED +
Sbjct: 145 AALPSHVVTMLDNFP-TNLHPMSQLSAAITALNSESNFAR--AEGISRTKYWELIYEDCM 201

Query: 215 TLIARLPAVAARIYRNTF 232
            LI ++P VAA+IY+N +
Sbjct: 202 DLITKIPCVAAKIYQNLY 219


ref|XP_395333.1| similar to ENSANGP00000015768 [Apis mellifera]
(984 aa)

Score: 190 bits (482), Expect: 1.0498e-46
Length: 441, Idn/Pos/Gap = 126/219/24 (28%/49%/5%)

Query:  37 SSATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYETSLLDP  96
           S++T L+EA+  KI      +   R++ G  V+   TV   Y G+  +  +V ETS  D 
Sbjct: 169 STSTDLKEALCEKIPIHYDLLRNFRQQHGSSVISQVTVENIYQGLNGVNTIVRETSETDS 228

Query:  97 QEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAA 156
           + GI++RG +IPE   LLPR    G+ P  E + WLLLTG++PT+ Q  S+  D   R  
Sbjct: 229 KYGIKYRGLTIPEVITLLPR---EGKSPSAEAVFWLLLTGDVPTKEQTASLIADWSIRRQ 285

Query: 157 VPPE---------VLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWE 207
              +         V  +L  LP +   P+ + S+A+++ +    + EA   GA   T WE
Sbjct: 286 KKKDWWSGPGGGIVGSVLQNLP-KTTTPLGKLSIALTVFESGKYIQEALKNGALSYTHWE 344

Query: 208 YCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDEL 267
           Y  ED++ L+A LPA+   I +      K    + ++ + +          ++ N   + 
Sbjct: 345 YTYEDSMELLATLPAIVGLIAKGELKNLKEDTGDWVQFLSECLYNTFDISEYQKNSLVDF 404

Query: 268 MRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLA---GPLHGLANQEVLRW 324
           +RLY+VL+AD  GG  S H   ++G+  S  Y++ A     LA    P  G  + E + +
Sbjct: 405 LRLYIVLNADENGGVPSVHITEILGA--SQLYINQALAAGALAYTDEPKSGTMS-EYMEF 461

Query: 325 LLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPH 384
             +++   G+     E L+      ++   +    G+   +  DP+YTA   +  +HLP+
Sbjct: 462 HSKIQRLFGHES-KEEKLKNYIATLIKREKLA---GYQETKFCDPKYTALINYTREHLPN 517

Query: 385 DEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRAL 444
           D   +L   L +++  ++ +  K K+ +P  +  +  + ++YGL +  F  VL  +SRAL
Sbjct: 518 DPNVKLSQTLTQILTMIM-KTAKGKDIYPEQNAIAAPIFQFYGLKDMKFNQVLLCMSRAL 576

Query: 445 GTLSSLVWDRALGLPIERPKS 465
           G ++S++W +A+  P+E P S
Sbjct: 577 GAIASIIWTKAVNAPVEHPVS 597


gb|AAR20842.1| citrate synthase [Pachycara brachycephalum]
(157 aa)

Score: 189 bits (479), Expect: 2.02942e-46
Length: 160, Idn/Pos/Gap = 90/112/3 (56%/70%/1%)

Query: 166 DELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAA 225
           D  P   +HPM+QFS A++ L  ES  A AY++G  KS +WE+  ED++ LIA+LP +AA
Sbjct:   1 DNFP-TNLHPMSQFSAAITALNSESSFARAYSEGVHKSKYWEFAYEDSMDLIAKLPCIAA  59

Query: 226 RIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVLHADHEGGNVSA 285
           +IYRN +  G  + A  I+   D        LG+   +F ELMRLYL +H+DHEGGNVSA
Sbjct:  60 KIYRNLYREGSSIGA--IDSNLDWSHNFTNMLGYSDAQFTELMRLYLTIHSDHEGGNVSA 117

Query: 286 HAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWL 325
           H   LVGSALSDPYLSF+A +NGLAGPLHGLANQEVL WL
Sbjct: 118 HTSHLVGSALSDPYLSFSAAMNGLAGPLHGLANQEVLVWL 157


ref|YP_008770.1| putative citrate (si)-synthase [Parachlamydia sp. UWE25]
emb|CAF24495.1| putative citrate (si)-synthase [Parachlamydia sp. UWE25]
(386 aa)

Score: 179 bits (454), Expect: 1.52949e-43
Length: 403, Idn/Pos/Gap = 132/194/32 (32%/48%/7%)

Query:  67 EVLDACTVNQAYGGMRSLKAMVYETSLLDPQEGIRFRGFSIPECQRLLPRAKPSGEQPLP 126
           EVL   T      G+R        TS +DP +G+ + G  + E            +Q  P
Sbjct:   3 EVLFEITKESLETGLRGYPVGYCTTSSVDPVKGLFYAGHPVSEI-----------DQWEP  51

Query: 127 EGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLL 186
           E +++LL  G +    +V    QDL  RA     ++  +++LP   +HPM  FS+A+ L 
Sbjct:  52 EQVIYLLYHGYVGKPEEVSRFSQDLLIRANCSTALIESIEKLPRN-IHPMKLFSIALLL- 109

Query: 187 QHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKV 246
                     A G      +    ED L LIA++P +AA +  +    GK   ++     
Sbjct: 110 ----------ASGFEGKNDYH---EDYLNLIAKVPEIAATVINHHAGWGKTKQSQPQLGY 156

Query: 247 DDMGMRLARSLGFELNEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGL 306
            +   ++         E     + + VLH DH GGN+SA   + V S L D Y S +A +
Sbjct: 157 MENFTQMLNVPDANQQELARAFKFFNVLHYDHGGGNLSAFVGKAVASGLEDLYGSMSAAM 216

Query: 307 NGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRR 366
             LAGP HG ANQ+ L ++ Q+ E+LG    T E L  L    L +G +I GFGHAVLR 
Sbjct: 217 CALAGPRHGKANQDCLTFVHQLVEELGEHS-TEEELERLIRAHLDKGELIFGFGHAVLRV 275

Query: 367 TDPRYTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYY 426
            DPR T   E   ++     + ++   L +V  +VL+   K+ +P+PNVD  SGILL   
Sbjct: 276 EDPRATLLYEVTNQYYASHALVKMAQLLRKVGSKVLQNNPKISDPYPNVDAISGILLTAA 335

Query: 427 GLVESNFYTVLFGVSRALGTLSSLVWDR-----ALGLPIERPK 464
           G   S +YTVLFG++R +G    +V++R       G PI RPK
Sbjct: 336 GFPCSEYYTVLFGLARVVGIGRQIVYERKEAREGKGTPIVRPK 378


gb|AAL67832.1| citrate synthase [Bos taurus]
(138 aa)

Score: 164 bits (414), Expect: 8.19224e-39
Length: 140, Idn/Pos/Gap = 77/104/2 (55%/74%/1%)

Query:  81 MRSLKAMVYETSLLDPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPT 140
           +R +K +VYETS+LDP EGIRFRG+SIPECQ+LLP+AK  GE+PLPEGL WLL+TG+IPT
Sbjct:   1 LRGMKGLVYETSVLDPDEGIRFRGYSIPECQKLLPKAK-GGEEPLPEGLFWLLVTGQIPT  59

Query: 141 ESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGA 200
           E QV  + Q+  +RAA+P  V+ +LD  P   +HPM+Q S  V+ L  ES  A AY++G 
Sbjct:  60 EEQVSWLSQEWAKRAALPSHVVTMLDNFP-TNLHPMSQLSADVTALNSESTFARAYSEGI 118

Query: 201 PKSTFWEYCLEDALTLIARL 220
            ++ +WE   ED++ LIA+L
Sbjct: 119 NRTKYWELIYEDSMDLIAKL 138


ref|XP_235086.3| PREDICTED: similar to citrate synthase [Rattus norvegicus]
(170 aa)

Score: 160 bits (406), Expect: 5.44465e-38
Length: 173, Idn/Pos/Gap = 83/109/3 (47%/63%/1%)

Query: 138 IPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYA 197
           +PTE QV  + Q+  +RA +P  V+ +LD  P   +HPM+Q S A++ L +ES  A AYA
Sbjct:   1 MPTEEQVSWLSQEWAKRAVLPSLVVTMLDNFP-TNLHPMSQLSAAITALNNESYFARAYA  59

Query: 198 QGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSL 257
           +G  ++ +WE   ED + LIA+LP VA +IYRN +     +  E I    D        L
Sbjct:  60 EGMSQTKYWELIYEDCMDLIAKLPCVATKIYRNLYREDTSI--EAIVPKLDWSHNFTNML 117

Query: 258 GFELNEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLA 310
           GF   +F ELM LYL +H+DHEGGNVSAH   LVGSALSDPYLS AA ++GLA
Sbjct: 118 GFMDPQFTELMHLYLTIHSDHEGGNVSAHTSHLVGSALSDPYLSLAAAMSGLA 170


gb|AAR20843.1| citrate synthase [Zoarces viviparus]
(122 aa)

Score: 136 bits (343), Expect: 1.13693e-30
Length: 124, Idn/Pos/Gap = 65/83/2 (52%/66%/1%)

Query: 179 FSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHV 238
           FS A++ L  ES  A AY++G  KS +WE+  ED++ LIA+LP +AA+IYRN +  G  +
Sbjct:   1 FSAAITALNSESSFARAYSEGVHKSKYWEFAYEDSMDLIAKLPCIAAKIYRNLYREGSSI  60

Query: 239 PAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDP 298
            A  I+   D        LG+   +F ELMRLYL +H+DHEGGNVSAH   LVGSALSDP
Sbjct:  61 GA--IDSNLDWSHNFTNMLGYSDAQFTELMRLYLTIHSDHEGGNVSAHTSHLVGSALSDP 118

Query: 299 YLSF 302
           YLSF
Sbjct: 119 YLSF 122


emb|CAH88434.1| hypothetical protein PC301067.00.0 [Plasmodium chabaudi]
(136 aa)

Score: 136 bits (342), Expect: 1.82928e-30
Length: 131, Idn/Pos/Gap = 65/88/1 (49%/67%/0%)

Query: 350 LREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVK 409
           L  G VIPG+GHAV    DPR+ A R FAL + P+D + +++   Y+V+P +L   GKVK
Sbjct:   1 LNSGRVIPGYGHAVFA-PDPRFLAFRNFALANFPNDPLVEILEMCYKVIPGILLATGKVK  59

Query: 410 NPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLPIERPKSVTTQ 469
           NP+PNVD +SG LL +YG++   +YTVLF +SRA+G +S LV  R L  P+ERPKSV   
Sbjct:  60 NPYPNVDCYSGSLLYHYGIIYPEYYTVLFAISRAIGVMSQLVLSRGLMFPLERPKSVDIY 119

Query: 470 WIREHFEKRSV 480
            +R+  EK  V
Sbjct: 120 NLRKICEKNYV 130


ref|ZP_00309292.1| COG0372: Citrate synthase [Cytophaga hutchinsonii]
(427 aa)

Score: 133 bits (334), Expect: 1.32155e-29
Length: 431, Idn/Pos/Gap = 127/209/54 (29%/48%/12%)

Query:  65 GEEVLDACTVNQAYG------GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQRLLPRA 117
           GE+ +D   +    G      G ++  A     + LD ++GI R+RG+ I +       +
Sbjct:  24 GEKAIDIAKLRDLTGYVTLDTGYKNTGATKSAITFLDGEQGILRYRGYPIEQLA-----S  78

Query: 118 KPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMT 177
           K S  +     + +LL+ GE+PT SQ+E+  + +++   +  ++ ++ D  P    HPM 
Sbjct:  79 KASFLE-----VSYLLIYGELPTTSQLENFKERIRKHTNLHEDIKKVFDGFP-SSAHPMG 132

Query: 178 QFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALT-LIARLPAVAARIYRNTFHGGK 236
             S AVS L        AY  G+   T  +  ++  +  L+A+LP +AA  YRN+     
Sbjct: 133 VLSSAVSSLT-------AYYPGSIDPTANDDEVDMTIVRLMAKLPTIAAWSYRNSKGQPL 185

Query: 237 HVPAEKIEKVDD-MGMRLAR-SLGFELNEFD-ELMRLYLVLHADHEGGNVSAHAVRLVGS 293
             P  K+   ++ + M   + +  FEL+    E +    +LHADHE  N S   VR+VGS
Sbjct: 186 MYPKPKLGYCENFLYMMFGQPNEDFELDPVVVEALNTLFILHADHEQ-NCSTSTVRIVGS 244

Query: 294 ALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREG 353
           A +  Y S AAG+N L GPLHG ANQEV+  L ++K    +   T + + ++  + +R  
Sbjct: 245 AHASLYSSIAAGINALWGPLHGGANQEVIEMLEEIK---ASGISTKDYIAKVKTKEVR-- 299

Query: 354 HVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSK--LYEVVPRVLEEQGKVKNP 411
             + GFGH V +  DPR        +K    D + +L  K    E+   +  EQ  + +P
Sbjct: 300 --LMGFGHRVYKNFDPRAK-----IIKKACDDILNKLGVKDPALEIAKEL--EQAALSDP 350

Query: 412 -------WPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLPIERPK 464
                  +PNVD +SGI+ +  GL  S+ +TV+F + R  G ++     R    PI RP+
Sbjct: 351 YFVERKLYPNVDFYSGIIYKALGL-RSDLFTVMFAIGRLPGWIAQWKELRDAKEPIGRPR 409

Query: 465 SVTTQWIREHF 475
            + T +    +
Sbjct: 410 QIYTGYTERDY 420


ref|YP_116867.1| putative citrate synthase [Nocardia farcinica IFM 10152]
dbj|BAD55503.1| putative citrate synthase [Nocardia farcinica IFM 10152]
(433 aa)

Score: 129 bits (324), Expect: 2.19913e-28
Length: 348, Idn/Pos/Gap = 104/172/26 (29%/49%/7%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LL+ GE+PT++Q++     ++R   +  ++ R  D  P    HPM   S AV+ L    
Sbjct:  93 YLLIYGELPTQAQLDDFTDRIRRHTLLHEDLKRFFDGFPRN-AHPMPVLSSAVNALS--- 148

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMG 250
               AY Q +      E      + L+A+LP +AA  Y+ +       P   +  V++  
Sbjct: 149 ----AYYQDSLDPRDPEQVELSTIRLLAKLPTIAAYSYKKSVGQPFLYPDNSLTLVENF- 203

Query: 251 MRLARSLGFELNEFD----ELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGL 306
           +R+      E  E D      + + L+LHADHE  N S   VRLVGS+ ++ + S + G+
Sbjct: 204 LRMTFGFPAEPYEVDPEVAAALDMLLILHADHEQ-NCSTSTVRLVGSSDANLFTSVSGGI 262

Query: 307 NGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRR 366
           N L GPLHG ANQ VL  L  +K + G+     E +R++  +   +G  + GFGH V R 
Sbjct: 263 NALWGPLHGGANQAVLEMLDDIKAQGGD---VKEFIRKV--KNKEDGVKLMGFGHRVYRN 317

Query: 367 TDPRYTAQREFA---LKHL-PHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGIL 422
            DPR    ++ A   L+ L   DE+F++   L E    + ++    +  +PNVD ++G++
Sbjct: 318 YDPRAAIAKKHADNILRKLGGDDELFEIAQALEEAA--LTDDYFVERRLYPNVDFYTGVI 375

Query: 423 LRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLPIERPKSVTTQW 470
            +  G   +  +TVLF + R  G ++      +  L I RP+ + T +
Sbjct: 376 YKAMGF-PTRMFTVLFAMGRLPGWIAHWREMHSEPLKIGRPRQIYTGY 422


ref|NP_939151.1| citrate synthase [Corynebacterium diphtheriae NCTC 13129]
emb|CAE49303.1| citrate synthase [Corynebacterium diphtheriae]
(435 aa)

Score: 127 bits (318), Expect: 8.71271e-28
Length: 387, Idn/Pos/Gap = 105/183/36 (27%/47%/9%)

Query:  90 ETSLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVC 148
           + + +D   GI R RG+ I +            E      + +LL+ G +PT  ++    
Sbjct:  64 KITYIDGDNGILRHRGYDIADL----------AENATFNEVSYLLIKGHLPTVDELHKFN 113

Query: 149 QDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEY 208
            +++    +  +     +  P +  HPM+  + +V++L         Y Q        E 
Sbjct: 114 NEIRHHTLLDEDFKSQFNIFPRD-AHPMSVLASSVNILS-------TYYQDQLNPLDEEQ 165

Query: 209 CLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDEL- 267
             +  + L+A++P +AA  YR +       P   +   ++  +R+      E  E D + 
Sbjct: 166 LDKATVRLLAKVPMLAAYAYRASKGAPYMYPDNSLNARENF-LRMMFGYPTEPYEVDPVV 224

Query: 268 ---MRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRW 324
              +   L+LHADHE  N S   VR++GSA ++ +++ A G+N L+GPLHG ANQ VL  
Sbjct: 225 AKALDKLLILHADHEQ-NCSTSTVRMIGSAQANMFVAVAGGINALSGPLHGGANQAVLEM 283

Query: 325 LLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFA---LKH 381
           L ++K   G+    T+ +  +  +   +G  + GFGH V +  DPR    +E A   L+H
Sbjct: 284 LEEIKANGGD---ATDFMNRV--KNKEKGVRLMGFGHRVYKNYDPRAAIVKETAHEILEH 338

Query: 382 LPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVS 441
           L  DE+  L  KL E+   + ++    +  +PNVD ++G++ R  G   ++F+TVLF + 
Sbjct: 339 LGGDELLDLAMKLEEIA--LSDDYFVSRKLYPNVDFYTGLIYRAMGF-PTDFFTVLFAIG 395

Query: 442 RALGTLSSLVWDRALGLPIERPKSVTT 468
           R  G ++      A    I RP+ + T
Sbjct: 396 RLPGWIAQYREQLATTTKINRPRQIYT 422


emb|CAA46902.1| citrate (si)-synthase [Corynebacterium glutamicum]
ref|YP_225121.1| CITRATE SYNTHASE [Corynebacterium glutamicum ATCC 13032]
emb|CAF19535.1| CITRATE SYNTHASE [Corynebacterium glutamicum ATCC 13032]
dbj|BAB98222.1| Citrate synthase [Corynebacterium glutamicum ATCC 13032]
sp|P42457|CISY_CORGL Citrate synthase
ref|NP_600058.1| citrate synthase [Corynebacterium glutamicum ATCC 13032]
(437 aa)

Score: 127 bits (318), Expect: 8.78571e-28
Length: 390, Idn/Pos/Gap = 108/186/40 (27%/47%/10%)

Query:  90 ETSLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVC 148
           + + +D   GI R+RG+ I +            E      + +LL+ GE+PT  ++    
Sbjct:  64 KITYIDGDAGILRYRGYDIADL----------AENATFNEVSYLLINGELPTPDELHKFN 113

Query: 149 QDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQ--HESKMAEAYAQGAPKSTFW 206
            +++    +  +     +  P +  HPM   + +V++L   ++ ++         K+T  
Sbjct: 114 DEIRHHTLLDEDFKSQFNVFPRD-AHPMATLASSVNILSTYYQDQLNPLDEAQLDKAT-- 170

Query: 207 EYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDE 266
                  + L+A++P +AA  +R         P   +   ++  +R+      E  E D 
Sbjct: 171 -------VRLMAKVPMLAAYAHRARKGAPYMYPDNSLNARENF-LRMMFGYPTEPYEIDP 222

Query: 267 LM----RLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVL 322
           +M       L+LHADHE  N S   VR++GSA ++ ++S A G+N L+GPLHG ANQ VL
Sbjct: 223 IMVKALDKLLILHADHEQ-NCSTSTVRMIGSAQANMFVSIAGGINALSGPLHGGANQAVL 281

Query: 323 RWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFA---L 379
             L  +K   G     TE + ++  +   +G  + GFGH V +  DPR    +E A   L
Sbjct: 282 EMLEDIKSNHGGD--ATEFMNKV--KNKEDGVRLMGFGHRVYKNYDPRAAIVKETAHEIL 337

Query: 380 KHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFG 439
           +HL  D++  L  KL E+   + ++    +  +PNVD ++G++ R  G   ++F+TVLF 
Sbjct: 338 EHLGGDDLLDLAIKLEEIA--LADDYFISRKLYPNVDFYTGLIYRAMGF-PTDFFTVLFA 394

Query: 440 VSRALGTLSSLVWDR-ALGLPIERPKSVTT 468
           + R  G ++       A G  I RP+ V T
Sbjct: 395 IGRLPGWIAHYREQLGAAGNKINRPRQVYT 424


gb|AAM70550.1| At2g42790/F7D19.21 [Arabidopsis thaliana]
gb|AAD21729.1| putative citrate synthase [Arabidopsis thaliana]
gb|AAK82477.1| At2g42790/F7D19.21 [Arabidopsis thaliana]
ref|NP_181807.1| citrate synthase, glyoxysomal, putative [Arabidopsis thaliana]
pir||C84858 probable citrate synthase [imported] - Arabidopsis thaliana
(509 aa)

Score: 122 bits (307), Expect: 2.05833e-26
Length: 399, Idn/Pos/Gap = 119/181/46 (29%/45%/11%)

Query:  92 SLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQD 150
           S +D  EGI R+RG+ I E            E      + +LL+ G +P+ESQ+      
Sbjct: 105 SYIDGDEGILRYRGYPIEEM----------AENSTFLEVAYLLMYGNLPSESQLSDWEFA 154

Query: 151 LKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCL 210
           + + +AVP  VL ++  +PH+  HPM     A+S L      A    +G       +   
Sbjct: 155 VSQHSAVPQGVLDIIQSMPHD-AHPMGVLVSAMSALSIFHPDANPALRGQDIYDSKQVRD 213

Query: 211 EDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLG---FELN-EFDE 266
           +  + +I + P +AA  Y         +P+  +   D+  + +  SLG   ++ N     
Sbjct: 214 KQIIRIIGKAPTIAAAAYLRMAGRPPVLPSGNLPYADNF-LYMLDSLGNRSYKPNPRLAR 272

Query: 267 LMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLL 326
           ++ +  +LHA+HE  N S  A R + S+  D Y + A  +  L GPLHG AN+ VL+ L 
Sbjct: 273 VLDILFILHAEHEM-NCSTAAARHLASSGVDVYTAVAGAVGALYGPLHGGANEAVLKMLS 331

Query: 327 QMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDE 386
           ++         T EN+ E           + GFGH V +  DPR    +  A      DE
Sbjct: 332 EIG--------TVENIPEFIEGVKNRKRKMSGFGHRVYKNYDPRAKVIKNLA------DE 377

Query: 387 MFQLVSK--LYEVV----PRVLEEQGKVKNP-WPNVDQHSGILLRYYGLVESNFYTVLFG 439
           +F +V K  L EV        L +   VK   +PNVD +SG++ R  G     F+TVLF 
Sbjct: 378 VFSIVGKDPLIEVAVALEKAALSDDYFVKRKLYPNVDFYSGLIYRAMGF-PPEFFTVLFA 436

Query: 440 VSRALGTLSSLVWDRALGLP---IERPKSVTTQ-WIREH 474
           + R  G LS   W  +L  P   I RP+ V T  W+R +
Sbjct: 437 IPRMAGYLSH--WKESLDDPDTKIMRPQQVYTGVWLRHY 473


gb|AAF04133.1| citrate synthase [Mycobacterium smegmatis]
(441 aa)

Score: 122 bits (305), Expect: 3.59997e-26
Length: 398, Idn/Pos/Gap = 109/182/46 (27%/45%/11%)

Query:  92 SLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQD 150
           + +D ++GI R+RG  I +            E+     + +LL+ GE+PT +Q+E     
Sbjct:  70 TYIDGEQGILRYRGIPIEQL----------AEKSTFIEVSYLLIYGELPTPTQLEEFTTK 119

Query: 151 LKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCL 210
           ++R   +  ++ R  D  P    HPM   S AV+ L        AY Q +      E   
Sbjct: 120 IQRHTLLHEDLKRFFDGFPRN-AHPMPVLSSAVNALS-------AYYQDSLDPKDDEQVE 171

Query: 211 EDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFD----- 265
              + L+A+LP +AA  Y+ +       P   +  V++    L  + GF    ++     
Sbjct: 172 LSTIRLLAKLPTIAAYAYKKSAGQPFLYPDNSLSLVENF---LRMTFGFPAEPYEVNPDV 228

Query: 266 -ELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRW 324
            + + +  +LHADHE  N S   VRLVGS+ ++ + S + G+N L GPLHG ANQ VL  
Sbjct: 229 AKALDMLFILHADHEQ-NCSTSTVRLVGSSQANLFTSISGGINALWGPLHGGANQAVLEM 287

Query: 325 LLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLP- 383
           L  +K   G+     E ++         G  + GFGH V +  DPR    ++ A + L  
Sbjct: 288 LDAIKADGGDTKKFMERVK-----NKEAGVKLMGFGHRVYKNYDPRAAIVKKTADQILET 342

Query: 384 ---HDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGV 440
               D++ ++   L EV   + ++    +  +PNVD ++G++ R  G   +  +TVLF +
Sbjct: 343 LGVQDDLLEIAKGLEEVA--LNDDYFIERKLYPNVDFYTGVIYRAMGF-PTRMFTVLFAL 399

Query: 441 SRALGTLSSLVWDRALGLP---IERPKSVTTQWIREHF 475
            R  G ++   W      P   I RP+ + T +    +
Sbjct: 400 GRLPGWIAH--WREMHEDPTTKIGRPRQLYTGYTERDY 435


ref|ZP_00120787.2| COG0372: Citrate synthase [Bifidobacterium longum DJO10A]
(430 aa)

Score: 121 bits (304), Expect: 4.47212e-26
Length: 362, Idn/Pos/Gap = 103/170/39 (28%/46%/10%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           WLL  GE+P+ ++ E  C D+  +  V  +    +   P    HPM+  + A++ L    
Sbjct:  85 WLLRHGELPSRAEYEQFCADINHKTMVGEDFRTFMGSFPRS-AHPMSVLASAINAL---- 139

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMG 250
             A  Y      S   +   E A  ++A+   + + I+R         P      VDD  
Sbjct: 140 --ATFYPDTTDISDT-DQLDEAAKIIMAKARTIVSYIFRRRRDEPMLYPDYARGYVDDF- 195

Query: 251 MRLARSLGFELNEFDEL----MRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGL 306
           +R+  ++ +E  E D L    +   L++HADHE  N S   VR+ GSA ++ Y + AAG+
Sbjct: 196 LRMCFAVPYEPFESDPLYVHALGRLLIIHADHEQ-NCSTSVVRIAGSAHANLYSAVAAGV 254

Query: 307 NGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRR 366
           N L+GPLHG AN+ VLR L  +++       + +++ E   +    G  I G GH V + 
Sbjct: 255 NALSGPLHGGANEAVLRQLKAIRD-------SGKSVAEFVRDAKENGQKISGLGHRVYKS 307

Query: 367 TDPRYTAQREFALK--------HLPHDE--MFQLVSKLYEVVPRVLEEQGKVKNPWPNVD 416
            DPR    R++  K         LP DE  +F + ++L ++   + +E    +N +PNVD
Sbjct: 308 YDPRAAIARKYLEKIMEREDTQKLPSDERALFAVATELEDIA--LNDEYFVSRNLYPNVD 365

Query: 417 QHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPKSVTTQWIRE 473
            ++G++ R  G  +   +T LF + R  G ++   +   L  P   I RP+ V T  +  
Sbjct: 366 FYTGLIYRAIGF-DPAMFTTLFALGRIPGWIAQ--YREMLADPNTKIGRPRQVYTGPVER 422

Query: 474 HF 475
            F
Sbjct: 423 DF 424


ref|NP_696881.1| citrate synthase 1 [Bifidobacterium longum NCC2705]
gb|AAN25517.1| citrate synthase 1 [Bifidobacterium longum NCC2705]
(430 aa)

Score: 121 bits (303), Expect: 5.24038e-26
Length: 362, Idn/Pos/Gap = 103/170/39 (28%/46%/10%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           WLL  GE+P+ ++ E  C D+  +  V  +    +   P    HPM+  + A++ L    
Sbjct:  85 WLLRHGELPSRAEYEQFCADINHKTMVGEDFRTFMGSFPRS-AHPMSVLASAINAL---- 139

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMG 250
             A  Y      S   +   E A  ++A+   + + I+R         P      VDD  
Sbjct: 140 --ATFYPDTTDISDN-DQLDEAAKIIMAKARTIVSYIFRRRRDEPMLYPDYARGYVDDF- 195

Query: 251 MRLARSLGFELNEFDEL----MRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGL 306
           +R+  ++ +E  E D L    +   L++HADHE  N S   VR+ GSA ++ Y + AAG+
Sbjct: 196 LRMCFAVPYEPFESDPLYVHALGRLLIIHADHEQ-NCSTSVVRIAGSAHANLYSAVAAGV 254

Query: 307 NGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRR 366
           N L+GPLHG AN+ VLR L  +++       + +++ E   +    G  I G GH V + 
Sbjct: 255 NALSGPLHGGANEAVLRQLKAIRD-------SGKSVAEFVRDAKENGQKISGLGHRVYKS 307

Query: 367 TDPRYTAQREFALK--------HLPHDE--MFQLVSKLYEVVPRVLEEQGKVKNPWPNVD 416
            DPR    R++  K         LP DE  +F + ++L ++   + +E    +N +PNVD
Sbjct: 308 YDPRAAIARKYLEKIMEREDTQKLPSDERALFAVATELEDIA--LNDEYFVSRNLYPNVD 365

Query: 417 QHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPKSVTTQWIRE 473
            ++G++ R  G  +   +T LF + R  G ++   +   L  P   I RP+ V T  +  
Sbjct: 366 FYTGLIYRAIGF-DPAMFTTLFALGRIPGWIAQ--YREMLADPNTKIGRPRQVYTGPVER 422

Query: 474 HF 475
            F
Sbjct: 423 DF 424


ref|YP_062516.1| citrate synthase [Leifsonia xyli subsp. xyli str. CTCB07]
gb|AAT89411.1| citrate synthase [Leifsonia xyli subsp. xyli str. CTCB07]
(425 aa)

Score: 119 bits (298), Expect: 2.09357e-25
Length: 398, Idn/Pos/Gap = 114/185/64 (28%/46%/16%)

Query:  92 SLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQD 150
           + +D   GI R+RG+ I +          +G     E + WLL+ GE+P+ S++      
Sbjct:  56 TYIDGDAGILRYRGYPIEQL---------AGNSTFLE-VAWLLIHGELPSASELADFDAR 105

Query: 151 LKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCL 210
           ++R   +  ++ R    LPH+  HPM+  S AVS L                STF++  L
Sbjct: 106 IRRHTLLHEDLRRFFSALPHD-AHPMSVLSSAVSAL----------------STFYQDSL 148

Query: 211 E---------DALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFEL 261
                       + L+A+LP +AA  ++ +       P   +  VD+  +RL      E 
Sbjct: 149 SVHDPEQVELSTVRLLAKLPVIAAYAHKKSIGQAFLYPDNSLSFVDNF-LRLNFGTLAEP 207

Query: 262 NEFDELM-----RLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGL 316
            E D ++     RL L+LH DHE  N S   VRLVGS  ++ + S +AG+N L GPLHG 
Sbjct: 208 YEVDPVLSRALERL-LILHEDHEQ-NASTSTVRLVGSTQANLFASVSAGINALYGPLHGG 265

Query: 317 ANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQRE 376
           AN+ VL+ L  +++         E ++         G  + GFGH V +  DPR    ++
Sbjct: 266 ANEAVLQMLAGIRDSGEGVQKFVERVK-----NKESGVKLMGFGHRVYKNFDPRARLVKQ 320

Query: 377 FALKHLP----HDEMFQLVSKLYEVVPRVLEEQGKV-KNPWPNVDQHSGILLRYYGLVES 431
            A + L     HD +  +  +L EV    L +Q  + +  +PNVD ++G++ +  G   +
Sbjct: 321 SADEVLSALGVHDPLLDIAKELEEV---ALADQYFIDRKLYPNVDFYTGVIYKAMGF-PT 376

Query: 432 NFYTVLFGVSRALGTLSSLVWDRAL---GLPIERPKSV 466
             +TVLF + R  G ++   W   +   G  I RP+ +
Sbjct: 377 RMFTVLFAIGRLPGWIAH--WREMMLDPGTKIGRPQQL 412


emb|CAB66275.1| citrate synthase. [Streptomyces coelicolor A3(2)]
gb|AAF14286.1| citrate synthase [Streptomyces coelicolor]
ref|NP_626968.1| citrate synthase. [Streptomyces coelicolor A3(2)]
(429 aa)

Score: 119 bits (297), Expect: 2.3727e-25
Length: 425, Idn/Pos/Gap = 116/194/65 (27%/45%/15%)

Query:  73 TVNQAYGGMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLW 131
           T++  YG   + K+ +   + LD + GI R+RG+ I +            E+     + +
Sbjct:  42 TLDSGYGNTAAYKSAI---TYLDGEAGILRYRGYPIEQL----------AERSSFVEVAY  88

Query: 132 LLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESK 191
           LL+ GE+PT  ++ +   ++ +   +  +V       P +  HPM   S  VS L     
Sbjct:  89 LLINGELPTVDELSAFKGEITQHTLLHEDVKNFYKGFPRD-AHPMAMLSSVVSAL----- 142

Query: 192 MAEAYAQGAPKSTFWEYCLE---------DALTLIARLPAVAARIYRNTFHGGKHVPAEK 242
                      STF++               + L+A+LP +AA  Y+ +       PA  
Sbjct: 143 -----------STFYQDSHNPFDERQRNLSTIRLLAKLPTIAAYAYKKSIGHPFVYPANN 191

Query: 243 IEKVDDMGMRLARSLGFELNEFDEL----MRLYLVLHADHEGGNVSAHAVRLVGSALSDP 298
           +  V++  +R+  S+  +  E D      +   L+LHADHE  N S   VRLVGS+ ++ 
Sbjct: 192 LGYVENF-LRMTFSVPAQEYELDPTVVAALDKLLILHADHEQ-NCSTSTVRLVGSSQANM 249

Query: 299 YLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPG 358
           + S +AG+N L GPLHG ANQ VL  L  +++  G+       +R++  +   +G  + G
Sbjct: 250 FASISAGINALWGPLHGGANQSVLEMLEGIRDAGGD---VDSFIRKV--KNKEDGVRLMG 304

Query: 359 FGHAVLRRTDPRYTAQREFALKHLP----HDEMFQLVSKLYEVVPRVLEEQGKV-KNPWP 413
           FGH V +  DPR    +  A   L      DE+  +  KL E     L +   V ++ +P
Sbjct: 305 FGHRVYKNFDPRAKIIKAAAHDVLSALGKSDELLDIALKLEE---HALSDDYFVSRSLYP 361

Query: 414 NVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPKSVTTQW 470
           NVD ++G++ R  G   +  +TVLF + R  G ++   W   +  P   I RP+ + T  
Sbjct: 362 NVDFYTGLIYRAMGF-PTEMFTVLFALGRLPGWIAQ--WHEMIKEPGSRIGRPRQIYTGV 418

Query: 471 IREHF 475
           +   F
Sbjct: 419 VERDF 423


ref|NP_737515.1| citrate synthase [Corynebacterium efficiens YS-314]
dbj|BAC17715.1| citrate synthase [Corynebacterium efficiens YS-314]
dbj|BAB86839.1| citrate synthase [Corynebacterium efficiens]
(470 aa)

Score: 118 bits (296), Expect: 3.60101e-25
Length: 390, Idn/Pos/Gap = 104/185/41 (26%/47%/10%)

Query:  90 ETSLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVC 148
           + + +D   GI R+RG+ I +            E      + +LL+ GE+PT  ++    
Sbjct:  98 KITYIDGDAGILRYRGYDIADL----------AENATFNEVSYLLIKGELPTPEELHKFN 147

Query: 149 QDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQ--HESKMAEAYAQGAPKSTFW 206
            +++    +  +     +  P +  HPM   + +V++L   ++ ++         K+T  
Sbjct: 148 DEIRHHTLLDEDFKSQFNVFPRD-AHPMATLASSVNILSTYYQDQLDPLDEAQLDKAT-- 204

Query: 207 EYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDE 266
                  + L+A++P +AA  +R         P   +   ++  +R+      E  E D 
Sbjct: 205 -------VRLMAKVPMLAAYAHRARKGAPYMYPDNSLNARENF-LRMMFGYPTEPYEVDP 256

Query: 267 LM----RLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVL 322
           +M       L+LHADHE  N S   VR++GSA ++ ++S A G+N L+GPLHG ANQ VL
Sbjct: 257 IMVKALDKLLILHADHEQ-NCSTSTVRMIGSAQANMFVSIAGGINALSGPLHGGANQAVL 315

Query: 323 RWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFA---L 379
             L ++    G+    T+ +  +  +   +G  + GFGH V +  DPR    ++ A   L
Sbjct: 316 EMLEEIAANGGD---ATDFMNRV--KNKEKGVRLMGFGHRVYKNYDPRAAIVKDTAHEIL 370

Query: 380 KHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFG 439
           +HL  D +  L  KL E+   + ++    +  +PNVD ++G++ R  G   ++F+TVLF 
Sbjct: 371 EHLGGDPLLDLALKLEEIA--LNDDYFISRKLYPNVDFYTGLIYRAMGF-PTDFFTVLFA 427

Query: 440 VSRALGTLSSLVWDRA-LGLPIERPKSVTT 468
           + R  G ++      A  G  I RP+ + T
Sbjct: 428 IGRLPGWIAHYREQLADPGAKINRPRQIYT 457


ref|NP_959763.1| GltA2 [Mycobacterium avium subsp. paratuberculosis str. k10]
gb|AAS03146.1| GltA2 [Mycobacterium avium subsp. paratuberculosis str. k10]
(431 aa)

Score: 118 bits (295), Expect: 4.78221e-25
Length: 366, Idn/Pos/Gap = 105/177/37 (28%/48%/10%)

Query:  92 SLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQD 150
           + +D   GI R+RG+ I +            E+     + +LL+ GE+P + Q+    + 
Sbjct:  60 TYIDGDAGILRYRGYPIEQL----------AEKSTFLEVSYLLIYGELPDKDQLAEFTKR 109

Query: 151 LKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCL 210
           ++    +  ++ R  D  P    HPM   S AV+ L        AY   +      E   
Sbjct: 110 IQLHTMLHEDLKRFFDGFPRN-AHPMPVLSSAVNALS-------AYYPDSLDPMDTEDVE 161

Query: 211 EDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFD-ELMR 269
              + L+A+LP +AA  Y+ +       P  K+  V++  +R+   L  E  + D E++R
Sbjct: 162 LSTIRLLAKLPTIAAYAYKKSVGQPFLYPDNKLSLVENF-LRMTFGLPAEPYQADPEVVR 220

Query: 270 ---LYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLL 326
              + L+LHADHE  N S   VRLVGS+ ++ + S + G+N L GPLHG ANQ VL  L 
Sbjct: 221 ALDMLLILHADHEQ-NCSTSTVRLVGSSQANLFTSISGGINALWGPLHGGANQAVLEMLE 279

Query: 327 QMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPH-- 384
           ++++   +    +E +R++  +    G  + GFGH V +  DPR    +E A K L    
Sbjct: 280 KIRQSDDD---VSEFVRKV--KNREAGVKLMGFGHRVYKNYDPRARIVKEQADKILAKLG 334

Query: 385 --DEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSR 442
             D++  +  +L E    + +E    +  +PNVD ++G++ R  G   +  +TVLF + R
Sbjct: 335 GDDDLLDIAKQLEEAA--LTDEYFIERKLYPNVDFYTGLIYRALGF-PTRMFTVLFALGR 391

Query: 443 ALGTLS 448
             G ++
Sbjct: 392 LPGWIA 397


emb|CAG35817.1| probable citrate synthase [Desulfotalea psychrophila LSv54]
ref|YP_064824.1| citrate synthase [Desulfotalea psychrophila LSv54]
(430 aa)

Score: 117 bits (293), Expect: 7.2579e-25
Length: 396, Idn/Pos/Gap = 109/185/41 (27%/46%/10%)

Query:  92 SLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQD 150
           + LD  +GI  +RG+SI +        + S          +L+L GE+P   ++E    D
Sbjct:  58 TYLDGDKGILNYRGYSIEDLAANCSFVEVS----------YLILHGELPNYQELEHFRHD 107

Query: 151 LKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCL 210
           + R A +  +++   D  P     PM+  S  ++ L +       Y +   K+  +    
Sbjct: 108 MNRFALLHEDMIHFFDHFP-PNASPMSILSTTINSLHN------FYPEMTAKTDPYGGIS 160

Query: 211 EDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDD-MGMRLAR-SLGFELN-EFDEL 267
                L+A++  +AA  Y+ +       P+ K+   ++ + M   R ++ +E+  E    
Sbjct: 161 VTTARLLAKVRTIAAFSYKKSNGYPLVYPSHKLNYCENFLNMMFDRPNIPYEIKPEVTAA 220

Query: 268 MRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQ 327
           +   L+LHADHE  N S   VRLVGSA  + Y S +AG++ L GPLHG ANQ V+  L +
Sbjct: 221 LNKLLILHADHEQ-NCSTSTVRLVGSAQVNLYASISAGVSALWGPLHGGANQAVIEMLEE 279

Query: 328 MKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLP---- 383
           + E   +     E  ++       +   + GFGH V +  DPR    +E   + L     
Sbjct: 280 IHESGDDYNYYIEKAKD-----KNDPFRLAGFGHRVYKTFDPRARIIKEACHEMLASMNV 334

Query: 384 HDEMFQLVSKLYEVVPRVLEEQGKV-KNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSR 442
           HD +  +  +L E   RVL +   + +N +PNVD +SGI+ R  G + ++ +TV+F + R
Sbjct: 335 HDPLLDIAFELEE---RVLRDDYFISRNLYPNVDFYSGIIYRAMG-IPTDMFTVMFALGR 390

Query: 443 ALGTLSSLVWDRALGLP---IERPKSVTTQWIREHF 475
             G ++   W      P   I RP+ + T + +  F
Sbjct: 391 LPGWIAQ--WTEMHADPNTKIGRPRQIYTGYKQRAF 424


ref|YP_169146.1| citrate synthase [Francisella tularensis subsp. tularensis Schu 4]
emb|CAG44704.1| citrate synthase [Francisella tularensis subsp. tularensis SCHU S4]
(424 aa)

Score: 116 bits (291), Expect: 1.20741e-24
Length: 361, Idn/Pos/Gap = 107/177/41 (29%/49%/11%)

Query: 129 LLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQH 188
           L + L+ GE+PT+ QV+S  Q++  +  V   V   +  +P +  HPM+     V++L  
Sbjct:  91 LCYALIYGELPTDEQVKSFRQEIINKMPVCEHVKAAIAAMP-QHTHPMSSLIAGVNVLA- 148

Query: 189 ESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHV-PAEKIEKVD 247
               AE    G  +S       E A  ++A++  +AA  YR+  HG K + P  +    +
Sbjct: 149 ----AEHIHNGQKESQD-----EVAKNIVAKIATIAAMAYRHN-HGKKFLEPKMEYGYAE 198

Query: 248 D-MGMRLARSLGFELNEFD-ELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAG 305
           + + M  A    ++ +E   + M    +LHADHE  N S   VRL GS  + PY +  AG
Sbjct: 199 NFLYMMFADDESYKPDELHIKAMDTIFMLHADHEQ-NASTSTVRLSGSTGNSPYAAIIAG 257

Query: 306 LNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHV--IPGFGHAV 363
           +  L GP HG AN+ VL+ L ++         +TEN+ +   +   +     + GFGH V
Sbjct: 258 ITALWGPAHGGANEAVLKMLSEIG--------STENIDKYIAKAKDKDDPFRLMGFGHRV 309

Query: 364 LRRTDPRYTAQR---EFALKHLPHDE--MFQLVSKLYEVVPRVLEEQGKVKNP-WPNVDQ 417
            + TDPR TA +   E  L  L H +  +  +  KL E+    L+++  ++   + NVD 
Sbjct: 310 YKNTDPRATAMKKNCEEILAKLGHSDNPLLTVAKKLEEI---ALQDEFFIERKLFSNVDF 366

Query: 418 HSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPKSVTTQWIREH 474
           +SGI+L+  G+ E + +T +F ++R  G +S   W   +  P   I RP+ + T     +
Sbjct: 367 YSGIILKAMGIPE-DMFTAIFALARTSGWISQ--WIEMVNDPAQKIGRPRQLYTGATNRN 423

Query: 475 F 475
           F
Sbjct: 424 F 424


ref|NP_302405.1| citrate synthase 1 [Mycobacterium leprae TN]
emb|CAB16687.1| citrate synthase [Mycobacterium leprae]
emb|CAC31085.1| citrate synthase 1 [Mycobacterium leprae]
pir||T45353 citrate synthase [imported] - Mycobacterium leprae
(431 aa)

Score: 116 bits (291), Expect: 1.45069e-24
Length: 419, Idn/Pos/Gap = 114/186/53 (27%/44%/12%)

Query:  73 TVNQAYGGMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLW 131
           T +  YG   S K+ +   + +D   GI R+RG+ I +            E+     + +
Sbjct:  44 TFDVGYGNTASTKSSI---TYIDGDAGILRYRGYPIEQL----------AEKSTFIEVCY  90

Query: 132 LLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESK 191
           LL+ GE+P   Q+      ++R   +  ++ R  D  P    HPM   S  V+ L     
Sbjct:  91 LLIYGELPATDQLAEFTHRIQRHTMLHEDLKRFYDGFPRN-AHPMPVLSSVVNALS---- 145

Query: 192 MAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGM 251
              AY Q A             + L+A+LP +AA  Y+ +       P      V++  +
Sbjct: 146 ---AYYQDALDPMDNGQVELSTIRLLAKLPTIAAYAYKKSVGQPFLYPDNAFSLVENF-L 201

Query: 252 RLARSLGFELNEFD-ELMR---LYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLN 307
           R+   L  E  E D E++R   +  +LHADHE  N S   VRLVGS+ ++ + S + G+N
Sbjct: 202 RMTFGLPAEPYEPDPEVVRALDMLFILHADHEQ-NCSTSTVRLVGSSRANLFTSISGGIN 260

Query: 308 GLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRT 367
            L GPLHG ANQ VL  L  ++E   +     + ++       + G  + GFGH V +  
Sbjct: 261 ALWGPLHGGANQAVLEMLEGIRESGDDVGGFVQKVK-----NCQAGVKLMGFGHRVYKNY 315

Query: 368 DPRYTAQREFALKHLPH----DEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILL 423
           DPR    +E A K L      D++  +   L E    + ++    +  +PNVD ++G++ 
Sbjct: 316 DPRARIVKEQADKILVKLGGDDDLLNIAKGLEEAA--LTDDYFIERKLYPNVDFYTGLIY 373

Query: 424 RYYGLVESNFYTVLFGVSRALGTLSSLVW-------DRALGLPIERPKSVTTQWIREHF 475
           R  G   +  +TVLF + R  G ++   W       D  +G    RP+ + T +    +
Sbjct: 374 RALGF-PTRMFTVLFALGRLPGWIAH--WREMHDEGDSKIG----RPRQIYTGYTERDY 425


gb|AAV59261.1| At3g58750 [Arabidopsis thaliana]
emb|CAB88292.1| citrate synthase-like protein [Arabidopsis thaliana]
gb|AAU95420.1| At3g58750 [Arabidopsis thaliana]
ref|NP_191434.1| citrate synthase, glyoxysomal, putative [Arabidopsis thaliana]
pir||T49158 citrate synthase-like protein - Arabidopsis thaliana
(514 aa)

Score: 116 bits (290), Expect: 1.56382e-24
Length: 414, Idn/Pos/Gap = 121/189/62 (29%/45%/14%)

Query:  94 LDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLK 152
           +D  EGI R+RG+ I E            E      + +LL+ G +P++SQ+      + 
Sbjct: 112 IDGDEGILRYRGYPIEEL----------AESSTFIEVAYLLMYGNLPSQSQLADWEFTVS 161

Query: 153 RRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQ--HESKMAEAYAQGAPKSTFWEYCL 210
           + +AVP  VL ++  +PH+  HPM     A+S L   H         Q   KS   +   
Sbjct: 162 QHSAVPQGVLDIIQSMPHD-AHPMGVLVSAMSALSIFHPDANPALSGQDIYKSK--QVRD 218

Query: 211 EDALTLIARLPAVAARIYRNTFHGGKHVPAEKIE-------KVDDMGMRLARSLGFELN- 262
           +  + ++ + P +AA  Y  T      +P+  +         +D MG R      ++ N 
Sbjct: 219 KQIVRILGKAPTIAAAAYLRTAGRPPVLPSANLSYSENFLYMLDSMGNR-----SYKPNP 273

Query: 263 EFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVL 322
               ++ +  +LHA+HE  N S  A R + S+  D Y + A  +  L GPLHG AN+ VL
Sbjct: 274 RLARVLDILFILHAEHEM-NCSTAAARHLASSGVDVYTACAGAVGALYGPLHGGANEAVL 332

Query: 323 RWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHL 382
           + L ++         T EN+ +           + GFGH V +  DPR    ++ A    
Sbjct: 333 KMLAEIG--------TAENIPDFIEGVKNRKRKMSGFGHRVYKNYDPRAKVIKKLA---- 380

Query: 383 PHDEMFQLVSK--LYEVV----PRVLEEQGKVKNP-WPNVDQHSGILLRYYGLVESNFYT 435
             DE+F +V +  L EV        L ++  VK   +PNVD +SG++ R  G     F+T
Sbjct: 381 --DEVFSIVGRDPLIEVAVALEKAALSDEYFVKRKLYPNVDFYSGLIYRAMGF-PPEFFT 437

Query: 436 VLFGVSRALGTLSSLVWDRALGLP---IERPKSVTTQ-WIREHFE---KRSVSA 482
           VLF V R  G LS   W  +L  P   I RP+   T  W+R H+E   +R++S+
Sbjct: 438 VLFAVPRMAGYLSH--WRESLDDPDTRIMRPQQAYTGVWMR-HYEPVRERTLSS 488


emb|CAD74943.1| citrate synthase [Rhodopirellula baltica SH 1]
ref|NP_867397.1| citrate synthase [Rhodopirellula baltica SH 1]
(495 aa)

Score: 116 bits (290), Expect: 1.6999e-24
Length: 397, Idn/Pos/Gap = 106/178/58 (26%/44%/14%)

Query:  92 SLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQD 150
           + LD ++GI R+RG+ I E  +     +          + +LL+ G++P   ++E+    
Sbjct: 124 TFLDGEKGILRYRGYPIEELAKSCDFVE----------VAYLLIFGDLPNAEEIETFRSG 173

Query: 151 LKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCL 210
           ++    +  ++    +  P +  HPM   S  V  L                STF++  +
Sbjct: 174 IRDHTMIHEDMRSFYNGFPRD-AHPMAILSSVVGAL----------------STFYQDSM 216

Query: 211 E---------DALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDD-MGMRLARSLGFE 260
           +             LIA+LP +AA  Y+ +       P  +++  ++ + M  A      
Sbjct: 217 DLNDPRQVEISLYRLIAKLPTIAAYSYKKSMGQPFMYPKNELDYCENFLHMMFATPTSDY 276

Query: 261 L--NEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLAN 318
           L   +F E + L  ++HADHE  N S   VR+VGS+ ++ + S +AG+  L GPLHG AN
Sbjct: 277 LVDPDFAEALNLLFIVHADHEQ-NCSTSTVRMVGSSNANLFASISAGIGALWGPLHGGAN 335

Query: 319 QEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFA 378
           +  +  L Q+    G+     +  ++           I GFGH V + +DPR T  R   
Sbjct: 336 EACVNMLEQIAADGGDVKKYVDMAKD-----KSNDFRIMGFGHRVYKNSDPRATIIRASC 390

Query: 379 LKHLPH----DEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFY 434
            K L      D +F++  KL EV  +  +E    +  +PNVD +SG++ R  G +    +
Sbjct: 391 DKLLAKLNLDDPLFEVAQKLEEVALK--DEYFIERKLYPNVDFYSGVIYRALG-IPVQMF 447

Query: 435 TVLFGVSRALGTLSSLVWDRALGLP---IERPKSVTT 468
           TVLF + R  G L+   W      P   I RP+ + T
Sbjct: 448 TVLFAIGRLPGWLAH--WREMHANPASRINRPRQIYT 482


ref|YP_056936.1| citrate synthase 1 [Propionibacterium acnes KPA171202]
gb|AAT83978.1| citrate synthase 1 [Propionibacterium acnes KPA171202]
(428 aa)

Score: 115 bits (288), Expect: 3.34147e-24
Length: 391, Idn/Pos/Gap = 107/189/43 (27%/48%/10%)

Query:  90 ETSLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVC 148
           + + +D ++G+ R+RG+ I +            EQ       +L+L GE+P+++Q++   
Sbjct:  55 QITYIDGEQGVLRYRGYPIEQL----------AEQSTFLETAYLVLYGELPSKAQLDGFE 104

Query: 149 QDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEY 208
           + ++R   +   +  L    P  R HPM   +  +  L   S  ++  +   P       
Sbjct: 105 ERIRRTTLIDERMRDLFRCFP-RRSHPMPVLAAGIMAL---STFSQKSSGTDPDQ----- 155

Query: 209 CLEDALT-LIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEF-DE 266
            +E A T LIA++P +AA  Y+N+       P   +  V +  +R++     E  EF DE
Sbjct: 156 -IEAATTRLIAKVPTLAAFGYKNSMGQPTLYPDNSLSYVQNF-IRMSFGFPTEPYEFNDE 213

Query: 267 LMR---LYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLR 323
           + R     L+LH DHE  N S   VR+V S+ ++ Y + AAG+N L+GP HG ANQ V  
Sbjct: 214 ITRALETLLILHVDHEQ-NCSTSTVRMVASSGANMYAAVAAGVNALSGPKHGGANQAV-- 270

Query: 324 WLLQMKEKLGNRPMTTENLRELCWETLREGHV-IPGFGHAVLRRTDPRYTAQREFALK-- 380
             L+M + + +  MTT+       +  +E  + + GFGH + +  DPR    ++ A +  
Sbjct: 271 --LEMLQFIRDSGMTTKEFVRKVKD--KESDIKLMGFGHRIYKNYDPRAAIIKKHADRIM 326

Query: 381 --HLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLF 438
             H   +++ ++  +L E    + ++  K +  +PNVD ++G++    G    N +TVLF
Sbjct: 327 ELHTGREDLLEIAKELEETA--LNDDYFKERKLYPNVDFYTGLIYEAMGF-PMNMFTVLF 383

Query: 439 GVSRALGTLSSLVWDRAL-GLPIERPKSVTT 468
            + R  G ++      A  G  I RP+ + T
Sbjct: 384 ALGRLPGWIAQYREQVASGGNKIWRPRQIFT 414


ref|NP_266826.1| citrate synthase [Lactococcus lactis subsp. lactis Il1403]
gb|AAK04768.1| citrate synthase (EC 4.1.3.7) [Lactococcus lactis subsp. lactis Il1403]
pir||F86708 citrate (si)-synthase (EC 4.1.3.7) [imported] - Lactococcus lactis subsp. lactis (strain IL1403)
(441 aa)

Score: 115 bits (287), Expect: 4.01474e-24
Length: 338, Idn/Pos/Gap = 94/163/29 (27%/48%/8%)

Query: 127 EGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLR--LLDELPHERMHPMTQFSVAVS 184
           E + +LLL GE+PT ++++     L  R  +P   +R  +L     + M+ M++  +A  
Sbjct:  85 EEMTYLLLFGELPTANELQEFQNLLASRRTLPEFFIRETILTNPSSDVMNSMSRCILA-- 142

Query: 185 LLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGK------HV 238
           L  ++ K+++            E  LE +  LIA  P +A   Y++  H  K      H 
Sbjct: 143 LASYDEKVSDISI---------ENVLEQSFGLIADFPLLAIYSYQSYVHYFKKESLYIHY 193

Query: 239 PAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDP 298
           P  K+   +++ +R+ R          +++ + L+LH +H GGN S     +V S+ +D 
Sbjct: 194 PDPKMTTAENI-LRMLRPDCHYTEVEAKVLDIALILHMEHGGGNNSTFTTHVVTSSGTDT 252

Query: 299 YLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRE----LCWETLREGH 354
           Y + AA L+ L GP HG AN +  + L  +KE + N     E  +     L  E   +  
Sbjct: 253 YATIAAALSSLKGPKHGGANIKAAKMLENIKENISNYEDDAEIEKYLHKILNKEVFDKQG 312

Query: 355 VIPGFGHAVLRRTDPRYTAQREFA---LKHLPHDEMFQLVSKLYEVVPRVLEEQGKV-KN 410
           +I G GHA+   +DPR+   + +    +K    +E F+L  K+  + P+V+ E  K+ K 
Sbjct: 313 LIYGIGHAIYSLSDPRFEVFKSYVETLVKEKGLEEEFKLYEKVARLAPKVISENRKIYKT 372

Query: 411 PWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLS 448
             PNVD +SG + R    +    +T LF ++R +G L+
Sbjct: 373 ICPNVDFYSGFVYRILE-IPQELFTPLFAIARIVGWLA 409


ref|YP_155895.1| Citrate synthase [Idiomarina loihiensis L2TR]
gb|AAV82346.1| Citrate synthase [Idiomarina loihiensis L2TR]
(426 aa)

Score: 114 bits (285), Expect: 7.26e-24
Length: 380, Idn/Pos/Gap = 112/167/41 (29%/43%/10%)

Query: 113 LLPRAKPSGEQPLPEGLL---WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELP 169
           LL R  P GE       L   ++LL GE PTE Q       + +   V   +    +   
Sbjct:  66 LLHRGYPIGELATKADYLEVCYMLLHGEAPTEKQYHEFKNTITKHTMVHQGIHNFFNGFR 125

Query: 170 HERMHPMTQFSV---AVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAAR 226
            +  HPM        A+S   H+        Q           L  A  LIA++P +AA 
Sbjct: 126 RD-AHPMAMLCAVTGALSSFYHDDLEIHDENQR----------LRSAYRLIAKIPTIAAM 174

Query: 227 IYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFD----ELMRLYLVLHADHEGGN 282
            Y+ +       P   +   ++  + +  S+  E  +        M     LHADHE  N
Sbjct: 175 AYKFSIGQPFVYPRNDLGYAENF-LNMMFSVPAEDYKISPAVARAMDRIFTLHADHEQ-N 232

Query: 283 VSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENL 342
            S   VRL GS+ ++PY   AAG+  L GP HG AN+  LR L ++   + N P   E  
Sbjct: 233 ASTSTVRLAGSSGANPYACIAAGVASLWGPAHGGANEACLRMLAEIGS-VENIPKYIEKA 291

Query: 343 RELCWETLREGHVIPGFGHAVLRRTDPRYTAQREF---ALKHLPHDEMFQLVSKLYEVVP 399
           ++       +   + GFGH V + TDPR T  RE     LK L  D+    V+   E + 
Sbjct: 292 KD-----KDDPFRLMGFGHRVYKNTDPRATVMRESCHEVLKELDRDDPLLDVAMELERI- 345

Query: 400 RVLEEQGKV-KNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALG- 457
             LE+   + K  +PNVD +SGI+L+  G + +N +TV+F +SR +G +S   W   +G 
Sbjct: 346 -ALEDDYFIEKKLFPNVDFYSGIVLKAIG-IPTNMFTVIFALSRTVGWVSH--WHEMMGE 401

Query: 458 --LPIERPKSVTTQWIREHF 475
               I RP+ + T + +  F
Sbjct: 402 ENQKIGRPRQLYTGYTKREF 421


ref|YP_002745.1| citrate synthase [Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130]
ref|NP_710971.1| Citrate synthase [Leptospira interrogans serovar Lai str. 56601]
gb|AAN47989.1| Citrate synthase [Leptospira interrogans serovar lai str. 56601]
gb|AAS71382.1| citrate synthase [Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130]
(429 aa)

Score: 113 bits (283), Expect: 1.02213e-23
Length: 424, Idn/Pos/Gap = 114/191/54 (26%/45%/12%)

Query:  66 EEVLDACTVNQAYG------GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQRLLPRAK 118
           E+ +D   + Q  G      G  +  A     + LD + GI R+RG  I +         
Sbjct:  25 EKAIDISKLRQQTGYVTLDNGYLNTGACTSAVTFLDGELGILRYRGIPIEQL--------  76

Query: 119 PSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQ 178
              E      + +LL+ G+IP++S+++    +L     +  ++ RL +  P +  HPM  
Sbjct:  77 --AENSTFTEVAYLLIYGKIPSDSELKKWNDELTMHTLIHEDLKRLYNGFPKDG-HPMAI 133

Query: 179 FSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHV 238
            S  +  L         Y Q +      E+     + L+A+ P +AA  Y+ +       
Sbjct: 134 MSSMIGSLS-------TYYQDSYDPENAEHRHISMIRLLAKFPTIAAFAYKKSIGQPTIH 186

Query: 239 PAEKIEKVDDMGMRLARSLGFELNEFD----ELMRLYLVLHADHEGGNVSAHAVRLVGSA 294
           P   ++   +  M +  S+  E  + D    + + L L+LHADHE  N S   VRLVGS+
Sbjct: 187 PLNSLDYCANF-MNMMFSVPSEDYKIDPEIVKALNLLLILHADHEQ-NCSTSTVRLVGSS 244

Query: 295 LSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGH 354
           L++ Y + +AG+  L GP HG ANQEV    L+M +++    +  + + E   +   +  
Sbjct: 245 LANLYGAISAGICALWGPRHGGANQEV----LEMLQEIQASGLPVKKIVEKAKDK-NDSF 299

Query: 355 VIPGFGHAVLRRTDPRYTAQR---EFALKHLP-HDEMFQLVSKLYEVV---PRVLEEQGK 407
            + GFGH V +  DPR    +   +  LK L   D +  +  +L E     P  +E    
Sbjct: 300 RLSGFGHRVYKNFDPRAKIIKKACDSVLKRLGVQDSLLDIAKELEETALHDPYFVE---- 355

Query: 408 VKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPK 464
            +  +PNVD +SGI+ R  G +  N +TV+F + R  G ++   W   +  P   I RP+
Sbjct: 356 -RKLYPNVDFYSGIIYRALG-IPVNMFTVMFAMGRLPGWIAQ--WKEMIESPDMKIGRPR 411

Query: 465 SVTT 468
            + T
Sbjct: 412 QIYT 415


dbj|BAC73042.1| putative citrate synthase [Streptomyces avermitilis MA-4680]
ref|NP_826507.1| putative citrate synthase [Streptomyces avermitilis MA-4680]
(429 aa)

Score: 113 bits (283), Expect: 1.03933e-23
Length: 424, Idn/Pos/Gap = 110/190/63 (25%/44%/14%)

Query:  73 TVNQAYGGMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLW 131
           T++  YG   + K+ +   + LD ++GI R+RG+ I +            E+     + +
Sbjct:  42 TLDSGYGNTAAYKSAI---TYLDGEQGILRYRGYPIEQL----------AERSTFLEVAY  88

Query: 132 LLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESK 191
           LL+ GE+PT  ++ +   ++ +   +  +V       P +  HPM   S  VS L     
Sbjct:  89 LLINGELPTVDELSTFKGEITQHTLLHEDVKNFYRGFPRD-AHPMAMLSSVVSAL----- 142

Query: 192 MAEAYAQGAPKSTFWEYCLE---------DALTLIARLPAVAARIYRNTFHGGKHVPAEK 242
                      STF++               + L+A+LP +AA  Y+ +       P   
Sbjct: 143 -----------STFYQDSHNPFDEKQRNLSTIRLLAKLPTIAAYAYKKSIGHPFVYPRND 191

Query: 243 IEKVDDMGMRLARSLGFELNEFDEL----MRLYLVLHADHEGGNVSAHAVRLVGSALSDP 298
           +  V++  +R+  S+  +  + D +    +   L+LHADHE  N S   VRLVGS+ ++ 
Sbjct: 192 LGYVENF-LRMTFSVPAQDYDLDPVVVSALDKLLILHADHEQ-NCSTSTVRLVGSSQANM 249

Query: 299 YLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPG 358
           + S +AG++ L GPLHG ANQ VL  L  ++   G+       ++        +G  + G
Sbjct: 250 FASISAGISALWGPLHGGANQSVLEMLEGIQTSGGDVDTFIRKVK-----NKEDGVKLMG 304

Query: 359 FGHAVLRRTDPRYTAQREFALKHLP----HDEMFQLVSKLYEVVPRVLEEQGKVKNPWPN 414
           FGH V +  DPR    +  A   L      DE+  +  KL E    + ++    +  +PN
Sbjct: 305 FGHRVYKNFDPRAKIIKAAAHDVLSALGKSDELLDIALKLEEHA--LADDYFVERKLYPN 362

Query: 415 VDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPKSVTTQWI 471
           VD ++G++ R  G   +  +TVLF + R  G ++   W   +  P   I RP+ + T  +
Sbjct: 363 VDFYTGLIYRAMGF-PTEMFTVLFALGRLPGWIAQ--WHEMIKEPGSRIGRPRQIYTGEV 419

Query: 472 REHF 475
              F
Sbjct: 420 LRDF 423


pdb|1AJ8|B Chain B, Citrate Synthase From Pyrococcus Furiosus
pdb|1AJ8|A Chain A, Citrate Synthase From Pyrococcus Furiosus
(371 aa)

Score: 112 bits (280), Expect: 2.23938e-23
Length: 360, Idn/Pos/Gap = 99/181/40 (27%/50%/11%)

Query:  94 LDPQEG-IRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLK 152
           +D +EG + +RG+S+ E   L             E +++LL  G++P+ S++E+  ++L 
Sbjct:  18 IDGKEGKLYYRGYSVEELAEL----------STFEEVVYLLWWGKLPSLSELENFKKELA  67

Query: 153 RRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLED 212
           +   +P EV+ +++ LP +  HPM      +S L +     +      P+  +       
Sbjct:  68 KSRGLPKEVIEIMEALP-KNTHPMGALRTIISYLGNIDDSGDIPV--TPEEVY-----RI 119

Query: 213 ALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFEL-NEFDELMRLY 271
            +++ A++P + A  YR   +G ++VP +  EK+      L    G E   E+++ M + 
Sbjct: 120 GISVTAKIPTIVANWYR-IKNGLEYVPPK--EKLSHAANFLYMLHGEEPPKEWEKAMDVA 176

Query: 272 LVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEK 331
           L+L+A+HE  N S  AV  VGS LSD Y +  AG+  L GP+HG A +E ++  +++   
Sbjct: 177 LILYAEHEI-NASTLAVMTVGSTLSDYYSAILAGIGALKGPIHGGAVEEAIKQFMEIG-- 233

Query: 332 LGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLV 391
                 + E + E  ++ L++   I G GH V +  DPR    +++A K L   ++F++ 
Sbjct: 234 ------SPEKVEEWFFKALQQKRKIMGAGHRVYKTYDPRARIFKKYASK-LGDKKLFEIA 286

Query: 392 SKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGL-VESNFYTVLFGVSRALGTLSSL 450
            +L  +V   L ++G       NVD  SG++  +YG+ +    YT +F + R  G  + L
Sbjct: 287 ERLERLVEEYLSKKGISI----NVDYWSGLV--FYGMKIPIELYTTIFAMGRIAGWTAHL 340


ref|NP_577932.1| citrate synthase [Pyrococcus furiosus DSM 3638]
gb|AAL80327.1| citrate synthase [Pyrococcus furiosus DSM 3638]
gb|AAB35835.2| citrate synthase [Pyrococcus furiosus]
sp|Q53554|CISY_PYRFU Citrate synthase
(377 aa)

Score: 112 bits (280), Expect: 2.39397e-23
Length: 360, Idn/Pos/Gap = 99/181/40 (27%/50%/11%)

Query:  94 LDPQEG-IRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLK 152
           +D +EG + +RG+S+ E   L             E +++LL  G++P+ S++E+  ++L 
Sbjct:  24 IDGKEGKLYYRGYSVEELAEL----------STFEEVVYLLWWGKLPSLSELENFKKELA  73

Query: 153 RRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLED 212
           +   +P EV+ +++ LP +  HPM      +S L +     +      P+  +       
Sbjct:  74 KSRGLPKEVIEIMEALP-KNTHPMGALRTIISYLGNIDDSGDIPV--TPEEVY-----RI 125

Query: 213 ALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFEL-NEFDELMRLY 271
            +++ A++P + A  YR   +G ++VP +  EK+      L    G E   E+++ M + 
Sbjct: 126 GISVTAKIPTIVANWYR-IKNGLEYVPPK--EKLSHAANFLYMLHGEEPPKEWEKAMDVA 182

Query: 272 LVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEK 331
           L+L+A+HE  N S  AV  VGS LSD Y +  AG+  L GP+HG A +E ++  +++   
Sbjct: 183 LILYAEHEI-NASTLAVMTVGSTLSDYYSAILAGIGALKGPIHGGAVEEAIKQFMEIG-- 239

Query: 332 LGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLV 391
                 + E + E  ++ L++   I G GH V +  DPR    +++A K L   ++F++ 
Sbjct: 240 ------SPEKVEEWFFKALQQKRKIMGAGHRVYKTYDPRARIFKKYASK-LGDKKLFEIA 292

Query: 392 SKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGL-VESNFYTVLFGVSRALGTLSSL 450
            +L  +V   L ++G       NVD  SG++  +YG+ +    YT +F + R  G  + L
Sbjct: 293 ERLERLVEEYLSKKGISI----NVDYWSGLV--FYGMKIPIELYTTIFAMGRIAGWTAHL 346


ref|NP_215411.1| PROBABLE CITRATE SYNTHASE I GLTA2 [Mycobacterium tuberculosis H37Rv]
emb|CAA97402.1| PROBABLE CITRATE SYNTHASE I GLTA2 [Mycobacterium tuberculosis H37Rv]
gb|AAK45166.1| citrate synthase [Mycobacterium tuberculosis CDC1551]
ref|NP_335352.1| citrate synthase [Mycobacterium tuberculosis CDC1551]
pir||E70782 probable gltA2 protein - Mycobacterium tuberculosis (strain H37RV)
sp|Q10530|CISY_MYCTU Citrate synthase 1
(431 aa)

Score: 111 bits (278), Expect: 3.85182e-23
Length: 378, Idn/Pos/Gap = 105/173/37 (27%/45%/9%)

Query:  80 GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEI 138
           G  +  A     + +D   GI R+RG+ I +            E+     + +LL+ GE+
Sbjct:  48 GFANTAAAKSSITYIDGDAGILRYRGYPIDQL----------AEKSTFIEVCYLLIYGEL  97

Query: 139 PTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQ 198
           P   Q+      ++R   +  ++ R  D  P    HPM   S  V+ L        AY Q
Sbjct:  98 PDTDQLAQFTGRIQRHTMLHEDLKRFFDGFPRN-AHPMPVLSSVVNALS-------AYYQ 149

Query: 199 GAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLG 258
            A             + L+A+LP +AA  Y+ +       P   +  V++  +RL     
Sbjct: 150 DALDPMDNGQVELSTIRLLAKLPTIAAYAYKKSVGQPFLYPDNSLTLVENF-LRLTFGFP 208

Query: 259 FELNEFD-ELMR---LYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLH 314
            E  + D E++R   +  +LHADHE  N S   VRLVGS+ ++ + S + G+N L GPLH
Sbjct: 209 AEPYQADPEVVRALDMLFILHADHEQ-NCSTSTVRLVGSSRANLFTSISGGINALWGPLH 267

Query: 315 GLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQ 374
           G ANQ VL  L  +++   +    +E +R++  +    G  + GFGH V +  DPR    
Sbjct: 268 GGANQAVLEMLEGIRDSGDD---VSEFVRKV--KNREAGVKLMGFGHRVYKNYDPRARIV 322

Query: 375 REFALKHLPH----DEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVE 430
           +E A K L      D +  +  +L E    + ++    +  +PNVD ++G++ R  G   
Sbjct: 323 KEQADKILAKLGGDDSLLGIAKELEEAA--LTDDYFIERKLYPNVDFYTGLIYRALGF-P 379

Query: 431 SNFYTVLFGVSRALGTLS 448
           +  +TVLF + R  G ++
Sbjct: 380 TRMFTVLFALGRLPGWIA 397


ref|NP_854577.1| PROBABLE CITRATE SYNTHASE I GLTA2 [Mycobacterium bovis AF2122/97]
emb|CAD93781.1| PROBABLE CITRATE SYNTHASE I GLTA2 [Mycobacterium bovis AF2122/97]
(431 aa)

Score: 111 bits (278), Expect: 4.08349e-23
Length: 378, Idn/Pos/Gap = 105/173/37 (27%/45%/9%)

Query:  80 GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEI 138
           G  +  A     + +D   GI R+RG+ I +            E+     + +LL+ GE+
Sbjct:  48 GFANTAAAKSSITYIDGDAGILRYRGYPIDQL----------AEKSTFIEVCYLLIYGEL  97

Query: 139 PTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQ 198
           P   Q+      ++R   +  ++ R  D  P    HPM   S  V+ L        AY Q
Sbjct:  98 PDTDQLAQFTGRIQRHTMLHEDLKRFFDGFPRN-AHPMPVLSSVVNALS-------AYYQ 149

Query: 199 GAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLG 258
            A             + L+A+LP +AA  Y+ +       P   +  V++  +RL     
Sbjct: 150 DALDPMDNGQVELSTIRLLAKLPTIAAYAYKKSVGQPFLYPDNSLTLVENF-LRLTFGFP 208

Query: 259 FELNEFD-ELMR---LYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLH 314
            E  + D E++R   +  +LHADHE  N S   VRLVGS+ ++ + S + G+N L GPLH
Sbjct: 209 AEPYQADPEVVRALDMLFILHADHEQ-NCSTSTVRLVGSSRANLFTSISGGINALWGPLH 267

Query: 315 GLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQ 374
           G ANQ VL  L  +++   +    +E +R++  +    G  + GFGH V +  DPR    
Sbjct: 268 GGANQAVLEMLEGIRDSGDD---VSEFVRKV--KNREAGVKLMGFGHRVYKNYDPRARIV 322

Query: 375 REFALKHLPH----DEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVE 430
           +E A K L      D +  +  +L E    + ++    +  +PNVD ++G++ R  G   
Sbjct: 323 KEQADKILAKLGGDDSLLGIAKELEEAA--LTDDYFIERKLYPNVDFYTGLIYRALGF-P 379

Query: 431 SNFYTVLFGVSRALGTLS 448
           +  +TVLF + R  G ++
Sbjct: 380 TRMFTVLFALGRLPGWIA 397


ref|NP_442192.1| citrate synthase [Synechocystis sp. PCC 6803]
dbj|BAA10262.1| citrate synthase [Synechocystis sp. PCC 6803]
sp|Q59977|CISY_SYNY3 Citrate synthase
(397 aa)

Score: 111 bits (277), Expect: 5.24494e-23
Length: 396, Idn/Pos/Gap = 110/181/50 (27%/45%/12%)

Query:  80 GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEI 138
           G+  + A     S +D  +GI  +RG  I E       AK S    +   L+W    G++
Sbjct:  14 GLAGVPAAKSRVSHVDGTDGILEYRGIRIEEL------AKSSSFIEVAYLLIW----GKL  63

Query: 139 PTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQ 198
           PT++++E    +++    +   +  ++   P E  HPM     + + L         YA+
Sbjct:  64 PTQAEIEEFEYEIRTHRRIKYHIRDMMKCFP-ETGHPMDALQTSAAAL------GLFYAR 116

Query: 199 GA---PKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLAR 255
            A   PK     Y     + L+A++P + A  +          P +K++   +    L  
Sbjct: 117 RALDDPK-----YIRAAVVRLLAKIPTMVAAFHMIREGNDPIQPNDKLDYASNFLYMLTE 171

Query: 256 SLGFELNEFD-ELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLH 314
               E + F  ++  + L LHA+H   N S  + R+  S L+DPY   A+ +  LAGPLH
Sbjct: 172 K---EPDPFAAKVFDVCLTLHAEHTM-NASTFSARVTASTLTDPYAVVASAVGTLAGPLH 227

Query: 315 GLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQ 374
           G AN+EV    L M E++G    + EN+R    + L     I GFGH V +  DPR    
Sbjct: 228 GGANEEV----LNMLEEIG----SVENVRPYVEKCLANKQRIMGFGHRVYKVKDPRAIIL 279

Query: 375 REFA---LKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVES 431
           ++ A      + HDE +++  +L +VV    EE    K  +PNVD +SG++ R    + +
Sbjct: 280 QDLAEQLFAKMGHDEYYEIAVELEKVV----EEYVGQKGIYPNVDFYSGLVYRKLD-IPA 334

Query: 432 NFYTVLFGVSRALGTLSSLVWDRALGL-PIERPKSV 466
           + +T LF ++R  G L+   W   L +  I RP  +
Sbjct: 335 DLFTPLFAIARVAGWLAH--WKEQLSVNKIYRPTQI 368


ref|YP_176211.1| citrate synthase II [Bacillus clausii KSM-K16]
dbj|BAD65250.1| citrate synthase II [Bacillus clausii KSM-K16]
(371 aa)

Score: 111 bits (277), Expect: 5.79728e-23
Length: 329, Idn/Pos/Gap = 96/154/32 (29%/46%/9%)

Query: 127 EGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLL 186
           E +++LL  GE+PT+ ++ES  + L  +A VP E+   +   P + +HPM     +VS+L
Sbjct:  42 EEVVYLLWNGELPTKEELESFSRALAEQAGVPDEIFEQMKAYPIDSVHPMAALRTSVSML 101

Query: 187 QHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKH--VPAEKIE 244
                 AE+  +        E     A+ L A++P + A   R     GK    P +++ 
Sbjct: 102 GLFDDEAESVEE--------EKNYRKAIKLQAKIPTIVAGFER--IRSGKEPIAPNKELS 151

Query: 245 KVDDMGMRLA--RSLGFELNEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSF 302
              +    L         +  F++     LVLHADHE  N S    R+  + LSD Y   
Sbjct: 152 FAANFLYMLTGENPDAISVKAFNKA----LVLHADHE-LNASTFTARVCVATLSDMYSGI 206

Query: 303 AAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHA 362
            A +  L GPLHG AN+ V++ LL+++E         E +     + L     I GFGH 
Sbjct: 207 TAAIGALKGPLHGGANEGVMKMLLEIEE--------FERVEPYIQKALDNKEKIMGFGHR 258

Query: 363 VLRRTDPRYTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGIL 422
           V +  DPR    RE + K L  D + +  SK Y++  R+ E     K   PNVD +S  +
Sbjct: 259 VYKNGDPRAKHLREMS-KQLT-DVIKE--SKWYDMSLRIEELVTTQKGLLPNVDFYSATV 314

Query: 423 LRYYGLVESNFYTVLFGVSRALGTLSSLV 451
               G ++ + +T +F +SR  G ++ ++
Sbjct: 315 YHSLG-IKHDLFTPIFAISRTSGWIAHIL 342


ref|NP_706514.1| citrate synthase [Shigella flexneri 2a str. 301]
gb|AAN42221.1| citrate synthase [Shigella flexneri 2a str. 301]
ref|NP_836288.1| citrate synthase [Shigella flexneri 2a str. 2457T]
gb|AAP16094.1| citrate synthase [Shigella flexneri 2a str. 2457T]
(427 aa)

Score: 111 bits (277), Expect: 5.99403e-23
Length: 359, Idn/Pos/Gap = 97/168/37 (27%/46%/10%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMT---QFSVAVSLLQ 187
           ++LL GE PT+ Q +     + R   +  ++ RL      +  HPM      + A++   
Sbjct:  88 YILLNGEKPTQEQYDEFKTTVTRHTMIHEQITRLFHAFRRDS-HPMAVMCGITGALAAFY 146

Query: 188 HESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVD 247
           H+S          P+          A  L++++P +AA  Y+ +       P   +    
Sbjct: 147 HDS-----LDVNNPRHREIA-----AFRLLSKMPTMAAMCYKYSIGQPFVYPRNDLSYAG 196

Query: 248 D-MGMRLARSLG-FELNE-FDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAA 304
           + + M  +     +E+N   +  M   L+LHADHE  N S   VR  GS+ ++P+   AA
Sbjct: 197 NFLNMMFSTPCEPYEVNPILERAMDRILILHADHEQ-NASTSTVRTAGSSGANPFACIAA 255

Query: 305 GLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVL 364
           G+  L GP HG AN+  L+    M E++ +     E +R    +   +   + GFGH V 
Sbjct: 256 GIASLWGPAHGGANEAALK----MLEEISSVKHIPEFVRRA--KDKNDSFRLMGFGHRVY 309

Query: 365 RRTDPRYTAQREF---ALKHL-PHDEMFQLVSKLYEVV---PRVLEEQGKVKNPWPNVDQ 417
           +  DPR T  RE     LK L   D++ ++  +L  +    P  +E     K  +PNVD 
Sbjct: 310 KNYDPRATVMRETCHEVLKELGTKDDLLEVAMELENIALNDPYFIE-----KKLYPNVDF 364

Query: 418 HSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLPIERPKSVTTQWIREHFE 476
           +SGI+L+  G + S+ +TV+F ++R +G ++      + G+ I RP+ + T + +  F+
Sbjct: 365 YSGIILKAMG-IPSSMFTVIFAMARTVGWIAHWSEMHSYGMKIARPRQLYTGYEKRDFK 422


pir||YKQPC citrate (si)-synthase (EC 4.1.3.7) - Acetobacter aceti
sp|P20901|CISY_ACEAC Citrate synthase (Acetic acid resistance protein)
gb|AAA21883.1| acetic acid resistance protein (aarA)
(436 aa)

Score: 110 bits (274), Expect: 1.10216e-22
Length: 368, Idn/Pos/Gap = 104/168/34 (28%/45%/9%)

Query: 113 LLPRAKPSG---EQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELP 169
           LL R  P     E    E +++LLL GE+P + Q ++    L     +  ++    +   
Sbjct:  74 LLHRGYPIAQLDENASYEEVIYLLLNGELPNKVQYDTFTNTLTNHTLLHEQIRNFFNGFR 133

Query: 170 HERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYR 229
            +  HPM      V  L      A   A  A +          A+ LIA++P +AA  Y+
Sbjct: 134 RD-AHPMAILCGTVGALSAFYPDANDIAIPANRDL-------AAMRLIAKIPTIAAWAYK 185

Query: 230 NTFHGGKHVPAEKIEKVDD-MGMRLAR-SLGFELNE-FDELMRLYLVLHADHEGGNVSAH 286
            T       P   +   ++ + M  AR S  +++N      M   L+LHADHE  N S  
Sbjct: 186 YTQGEAFIYPRNDLNYAENFLSMMFARMSEPYKVNPVLARAMNRILILHADHEQ-NASTS 244

Query: 287 AVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELC 346
            VRL GS  ++P+   AAG+  L GP HG AN+ VL+ L ++ +K  N P     +++  
Sbjct: 245 TVRLAGSTGANPFACIAAGIAALWGPAHGGANEAVLKMLARIGKK-ENIPAFIAQVKD-- 301

Query: 347 WETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPH-----DEMFQLVSKLYEVVPRV 401
                 G  + GFGH V +  DPR    ++   + L       D +  L  +L ++   +
Sbjct: 302 ---KNSGVKLMGFGHRVYKNFDPRAKIMQQTCHEVLTELGIKDDPLLDLAVELEKIA--L 356

Query: 402 LEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP-- 459
            ++    +  +PNVD +SGI+L+  G + ++ +TVLF V+R  G +S   W   +  P  
Sbjct: 357 SDDYFVQRKLYPNVDFYSGIILKAMG-IPTSMFTVLFAVARTTGWVSQ--WKEMIEEPGQ 413

Query: 460 -IERPKSV 466
            I RP+ +
Sbjct: 414 RISRPRQL 421


dbj|BAB34168.1| citrate synthase [Escherichia coli O157:H7]
ref|NP_308772.1| citrate synthase [Escherichia coli O157:H7]
pir||A99722 citrate synthase [imported] - Escherichia coli (strain O157:H7, substrain RIMD 0509952)
(427 aa)

Score: 110 bits (274), Expect: 1.24911e-22
Length: 359, Idn/Pos/Gap = 97/168/37 (27%/46%/10%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMT---QFSVAVSLLQ 187
           ++LL GE PT+ Q +     + R   +  ++ RL      +  HPM      + A++   
Sbjct:  88 YILLNGEKPTQEQYDEFKTTVTRHTMIHEQITRLFHAFRRDS-HPMAVMCGITGALAAFY 146

Query: 188 HESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVD 247
           H+S          P+          A  L++++P +AA  Y+ +       P   +    
Sbjct: 147 HDS-----LDVNNPRHREIA-----AFRLLSKMPTMAAMCYKYSIGQPFVYPRNDLSYAG 196

Query: 248 D-MGMRLARSLG-FELNE-FDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAA 304
           + + M  +     +E+N   +  M   L+LHADHE  N S   VR  GS+ ++P+   AA
Sbjct: 197 NFLNMMFSTPCEPYEVNPILERAMDRILILHADHEQ-NASTSTVRTAGSSGANPFACIAA 255

Query: 305 GLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVL 364
           G+  L GP HG AN+  L+    M E++ +     E +R    +   +   + GFGH V 
Sbjct: 256 GIASLWGPAHGGANEAALK----MLEEISSVKHIPEFVRRA--KDKNDSFRLMGFGHRVY 309

Query: 365 RRTDPRYTAQREF---ALKHL-PHDEMFQLVSKLYEVV---PRVLEEQGKVKNPWPNVDQ 417
           +  DPR T  RE     LK L   D++ ++  +L  +    P  +E     K  +PNVD 
Sbjct: 310 KNYDPRATVMRETCHEVLKELGTKDDLLEVAMELENIALNDPYFIE-----KKLYPNVDF 364

Query: 418 HSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLPIERPKSVTTQWIREHFE 476
           +SGI+L+  G + S+ +TV+F ++R +G ++      + G+ I RP+ + T + +  F+
Sbjct: 365 YSGIILKAMG-IPSSMFTVIFAMARTVGWIAHWSEMHSDGMKIARPRQLYTGYEKRDFK 422


ref|NP_752726.1| Citrate synthase [Escherichia coli CFT073]
gb|AAN79269.1| Citrate synthase [Escherichia coli CFT073]
ref|NP_415248.1| citrate synthase [Escherichia coli K12]
gb|AAC73814.1| citrate synthase [Escherichia coli K12]
dbj|BAA35387.1| Citrate synthase (EC 4.1.3.7). [Escherichia coli K12]
sp|P00891|CISY_ECOLI Citrate synthase
(427 aa)

Score: 110 bits (274), Expect: 1.24911e-22
Length: 359, Idn/Pos/Gap = 97/168/37 (27%/46%/10%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMT---QFSVAVSLLQ 187
           ++LL GE PT+ Q +     + R   +  ++ RL      +  HPM      + A++   
Sbjct:  88 YILLNGEKPTQEQYDEFKTTVTRHTMIHEQITRLFHAFRRDS-HPMAVMCGITGALAAFY 146

Query: 188 HESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVD 247
           H+S          P+          A  L++++P +AA  Y+ +       P   +    
Sbjct: 147 HDS-----LDVNNPRHREIA-----AFRLLSKMPTMAAMCYKYSIGQPFVYPRNDLSYAG 196

Query: 248 D-MGMRLARSLG-FELNE-FDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAA 304
           + + M  +     +E+N   +  M   L+LHADHE  N S   VR  GS+ ++P+   AA
Sbjct: 197 NFLNMMFSTPCEPYEVNPILERAMDRILILHADHEQ-NASTSTVRTAGSSGANPFACIAA 255

Query: 305 GLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVL 364
           G+  L GP HG AN+  L+    M E++ +     E +R    +   +   + GFGH V 
Sbjct: 256 GIASLWGPAHGGANEAALK----MLEEISSVKHIPEFVRRA--KDKNDSFRLMGFGHRVY 309

Query: 365 RRTDPRYTAQREF---ALKHL-PHDEMFQLVSKLYEVV---PRVLEEQGKVKNPWPNVDQ 417
           +  DPR T  RE     LK L   D++ ++  +L  +    P  +E     K  +PNVD 
Sbjct: 310 KNYDPRATVMRETCHEVLKELGTKDDLLEVAMELENIALNDPYFIE-----KKLYPNVDF 364

Query: 418 HSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLPIERPKSVTTQWIREHFE 476
           +SGI+L+  G + S+ +TV+F ++R +G ++      + G+ I RP+ + T + +  F+
Sbjct: 365 YSGIILKAMG-IPSSMFTVIFAMARTVGWIAHWSEMHSDGMKIARPRQLYTGYEKRDFK 422


gb|AAG55044.1| citrate synthase [Escherichia coli O157:H7 EDL933]
pir||H85572 citrate synthase [imported] - Escherichia coli (strain O157:H7, substrain EDL933)
ref|NP_286436.1| citrate synthase [Escherichia coli O157:H7 EDL933]
(427 aa)

Score: 110 bits (274), Expect: 1.28077e-22
Length: 359, Idn/Pos/Gap = 97/168/37 (27%/46%/10%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMT---QFSVAVSLLQ 187
           ++LL GE PT+ Q +     + R   +  ++ RL      +  HPM      + A++   
Sbjct:  88 YILLNGEKPTQEQYDEFKTTVTRHTMIHEQITRLFHAFRRDS-HPMAVMCGITGALAAFY 146

Query: 188 HESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVD 247
           H+S          P+          A  L++++P +AA  Y+ +       P   +    
Sbjct: 147 HDS-----LDVNNPRHREIA-----AFRLLSKMPTMAAMCYKYSIGQPFVYPRNDLSYAG 196

Query: 248 D-MGMRLARSLG-FELNE-FDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAA 304
           + + M  +     +E+N   +  M   L+LHADHE  N S   VR  GS+ ++P+   AA
Sbjct: 197 NFLNMMFSTPCEPYEVNPILERAMDRILILHADHEQ-NASTSTVRTAGSSGANPFACIAA 255

Query: 305 GLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVL 364
           G+  L GP HG AN+  L+    M E++ +     E +R    +   +   + GFGH V 
Sbjct: 256 GIASLWGPAHGGANEAALK----MLEEISSVKHIPEFVRRA--KDKNDSFRLMGFGHRVY 309

Query: 365 RRTDPRYTAQREF---ALKHL-PHDEMFQLVSKLYEVV---PRVLEEQGKVKNPWPNVDQ 417
           +  DPR T  RE     LK L   D++ ++  +L  +    P  +E     K  +PNVD 
Sbjct: 310 KNYDPRATVMRETCHEVLKELGTKDDLLEVAMELENIALNDPYFIE-----KKLYPNVDF 364

Query: 418 HSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLPIERPKSVTTQWIREHFE 476
           +SGI+L+  G + S+ +TV+F ++R +G ++      + G+ I RP+ + T + +  F+
Sbjct: 365 YSGIILKAMG-IPSSMFTVIFAMARTVGWIAHWSEMHSDGMKIARPRQLYTGYEKRDFK 422


ref|YP_049462.1| citrate synthase [Erwinia carotovora subsp. atroseptica SCRI1043]
emb|CAG74266.1| citrate synthase [Erwinia carotovora subsp. atroseptica SCRI1043]
(428 aa)

Score: 110 bits (274), Expect: 1.38065e-22
Length: 415, Idn/Pos/Gap = 112/183/58 (26%/44%/13%)

Query:  80 GMRSLKAMVYETSLLDPQEGIRF-RGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEI 138
           G  S  +   + + +D  EGI   RGF I +            E+     + ++LL GE 
Sbjct:  46 GFTSTASCESKITYIDGDEGILLHRGFPIAQL----------AEKSNYLEVCYILLFGEP  95

Query: 139 PTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQF---SVAVSLLQHESK--MA 193
           PT  Q E+    + R   +  ++ RL      +  HPM      + A++   H+S     
Sbjct:  96 PTAEQYETFKTTVTRHTMIHEQITRLFHGFRRDS-HPMAVLCGVTGALAAFYHDSLDISI 154

Query: 194 EAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRL 253
           E + + A            A  L++++P VAA  Y+ +       P   +      G  L
Sbjct: 155 ERHREIA------------AYRLLSKMPTVAAMCYKYSLGQPFVYPKNNLSYA---GNFL 199

Query: 254 ARSLGFELNEF------DELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLN 307
                    E+      +  M   L+LHADHE  N S   VR  GS+ ++P+   AAG+ 
Sbjct: 200 HMMFSTPCEEYVVNPVLERAMDRILILHADHEQ-NASTSTVRTAGSSGANPFACIAAGIA 258

Query: 308 GLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRT 367
            L GP HG AN+  LR +L+    + + P   E  ++       +   + GFGH V +  
Sbjct: 259 SLWGPAHGGANEACLR-MLEEISSVEHIPAFIERAKD-----KNDSFRLMGFGHRVYKNH 312

Query: 368 DPRYTAQREF---ALKHLPH-DEMFQLVSKLYEVV---PRVLEEQGKVKNPWPNVDQHSG 420
           DPR T  RE     LK L   D++ ++  +L  +    P  +E     K  +PNVD +SG
Sbjct: 313 DPRATVMRETCHEVLKELGRKDDLLEVAMELEHIALNDPYFIE-----KKLYPNVDFYSG 367

Query: 421 ILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLPIERPKSVTTQWIREHF 475
           I+L+  G + S+ +TV+F ++R +G ++      A G+ I RP+ + T + +  F
Sbjct: 368 IILKAMG-IPSSMFTVIFAMARTVGWIAHWSEMHADGIKIARPRQLYTGYDKRDF 421


pdb|1K3P|B Chain B, Three Dimensional Structure Analysis Of The Type Ii Citrate Synthase From E.Coli
pdb|1K3P|A Chain A, Three Dimensional Structure Analysis Of The Type Ii Citrate Synthase From E.Coli
(426 aa)

Score: 109 bits (273), Expect: 1.42751e-22
Length: 359, Idn/Pos/Gap = 97/167/37 (27%/46%/10%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMT---QFSVAVSLLQ 187
           ++LL GE PT+ Q +     + R   +  ++ RL      +  HPM      + A++   
Sbjct:  87 YILLNGEKPTQEQYDEFKTTVTRHTMIHEQITRLFHAFRRDS-HPMAVMCGITGALAAFY 145

Query: 188 HESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVD 247
           H+S          P+          A  L++++P +AA  Y+ +       P   +    
Sbjct: 146 HDS-----LDVNNPRHREIA-----AFRLLSKMPTMAAMCYKYSIGQPFVYPRNDLSYAG 195

Query: 248 D-MGMRLARSLG-FELNE-FDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAA 304
           + + M  +     +E+N   +  M   L+LHADHE  N S   VR  GS+ ++P+   AA
Sbjct: 196 NFLNMMFSTPCEPYEVNPILERAMDRILILHADHEQ-NASTSTVRTAGSSGANPFACIAA 254

Query: 305 GLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVL 364
           G+  L GP HG AN+  L+    M E++ +     E  R    +   +   + GFGH V 
Sbjct: 255 GIASLWGPAHGGANEAALK----MLEEISSVKHIPEFFRRA--KDKNDSFRLMGFGHRVY 308

Query: 365 RRTDPRYTAQREF---ALKHL-PHDEMFQLVSKLYEVV---PRVLEEQGKVKNPWPNVDQ 417
           +  DPR T  RE     LK L   D++ ++  +L  +    P  +E     K  +PNVD 
Sbjct: 309 KNYDPRATVMRETCHEVLKELGTKDDLLEVAMELENIALNDPYFIE-----KKLYPNVDF 363

Query: 418 HSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLPIERPKSVTTQWIREHFE 476
           +SGI+L+  G + S+ +TV+F ++R +G ++      + G+ I RP+ + T + +  F+
Sbjct: 364 YSGIILKAMG-IPSSMFTVIFAMARTVGWIAHWSEMHSDGMKIARPRQLYTGYEKRDFK 421


gb|AAA23892.1| citrate synthase [Escherichia coli K12]
prf||0912181A synthase,citrate
(427 aa)

Score: 109 bits (273), Expect: 1.42751e-22
Length: 359, Idn/Pos/Gap = 97/167/37 (27%/46%/10%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMT---QFSVAVSLLQ 187
           ++LL GE PT+ Q +     + R   +  ++ RL      +  HPM      + A++   
Sbjct:  88 YILLNGEKPTQEQYDEFKTTVTRHTMIHEQITRLFHAFRRDS-HPMAVMCGITGALAAFY 146

Query: 188 HESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVD 247
           H+S          P+          A  L++++P +AA  Y+ +       P   +    
Sbjct: 147 HDS-----LDVNNPRHREIA-----AFRLLSKMPTMAAMCYKYSIGQPFVYPRNDLSYAG 196

Query: 248 D-MGMRLARSLG-FELNE-FDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAA 304
           + + M  +     +E+N   +  M   L+LHADHE  N S   VR  GS+ ++P+   AA
Sbjct: 197 NFLNMMFSTPCEPYEVNPILERAMDRILILHADHEQ-NASTSTVRTAGSSGANPFACIAA 255

Query: 305 GLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVL 364
           G+  L GP HG AN+  L+    M E++ +     E  R    +   +   + GFGH V 
Sbjct: 256 GIASLWGPAHGGANEAALK----MLEEISSVKHIPEFFRRA--KDKNDSFRLMGFGHRVY 309

Query: 365 RRTDPRYTAQREF---ALKHL-PHDEMFQLVSKLYEVV---PRVLEEQGKVKNPWPNVDQ 417
           +  DPR T  RE     LK L   D++ ++  +L  +    P  +E     K  +PNVD 
Sbjct: 310 KNYDPRATVMRETCHEVLKELGTKDDLLEVAMELENIALNDPYFIE-----KKLYPNVDF 364

Query: 418 HSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLPIERPKSVTTQWIREHFE 476
           +SGI+L+  G + S+ +TV+F ++R +G ++      + G+ I RP+ + T + +  F+
Sbjct: 365 YSGIILKAMG-IPSSMFTVIFAMARTVGWIAHWSEMHSDGMKIARPRQLYTGYEKRDFK 422


ref|NP_820394.1| citrate synthase [Coxiella burnetii RSA 493]
gb|AAO90908.1| citrate synthase [Coxiella burnetii RSA 493]
pir||JQ1392 citrate (si)-synthase (EC 4.1.3.7) - Coxiella burnetii
sp|P18789|CISY_COXBU Citrate synthase
gb|AAA23307.1| citrate synthase (g1tA) (EC 4.1.3.7)
(430 aa)

Score: 109 bits (273), Expect: 1.53883e-22
Length: 424, Idn/Pos/Gap = 110/194/51 (25%/45%/12%)

Query:  64 FGEEVLDACTVNQ--AYG---GMRSLKAMVYETSLLDPQEGIR-FRGFSIPECQRLLPRA 117
            G++V+D  T+    AY    G  S  A   + + +D ++GI  +RG+ I +        
Sbjct:  24 LGKDVIDVKTLGNHGAYALDVGFYSTAACESKITFIDGEKGILLYRGYPIDQL-------  76

Query: 118 KPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMT 177
               ++     + +LL+ GE+P + + E   + +K   +V  +V +  +   H   HPM 
Sbjct:  77 ---ADKSDYMEVCYLLMYGELPNKGEKEKFVRTIKEHTSVYEQVTKFFNGF-HYDAHPMA 132

Query: 178 QFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKH 237
                +  L      A    + A +          A+ LIA++P +AA  Y+ +      
Sbjct: 133 MVLSTIGALSAFYHDALDITKPADREL-------SAIRLIAKMPTLAAMSYKYSIGQPFM 185

Query: 238 VPAEKIEKVDDMGMRLARSLGFELNEFDEL----MRLYLVLHADHEGGNVSAHAVRLVGS 293
            P   +   ++  + +     +E  E D +    M    +LHADHE  N S   VR+ GS
Sbjct: 186 HPRRAMNYAENF-LHMLFGTPYEETEPDPVLARAMDRIFILHADHEQ-NASTTTVRVAGS 243

Query: 294 ALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREG 353
             ++P+   +AG++ L GP HG AN+      L M  K+G+     + +++   +   + 
Sbjct: 244 TGANPFACISAGISALWGPAHGGANEAC----LNMLRKIGDEKNIGQYIKKA--KDKNDP 297

Query: 354 HVIPGFGHAVLRRTDPRYTAQREFALKHLP----HDE-MFQLVSKLYEVVPRVLEEQGKV 408
             + GFGH V +  DPR    ++   + L     H+E +F+L  KL ++    LE+   +
Sbjct: 298 FRLMGFGHRVYKNYDPRAKVMQKTCYEVLDAVGRHNEPLFKLAIKLEKI---ALEDDYFI 354

Query: 409 -KNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPK 464
            K  +PNVD +SG+ L   G + SN +TV+F +SR +G +S   W   +  P   + RP+
Sbjct: 355 EKKLYPNVDFYSGLTLNAIG-IPSNMFTVIFALSRTVGWISH--WMEMMSSPDHRLARPR 411

Query: 465 SVTT 468
            + T
Sbjct: 412 QLYT 415


ref|NP_928723.1| citrate synthase [Photorhabdus luminescens subsp. laumondii TTO1]
emb|CAE13718.1| citrate synthase [Photorhabdus luminescens subsp. laumondii TTO1]
(427 aa)

Score: 109 bits (273), Expect: 1.744e-22
Length: 362, Idn/Pos/Gap = 95/166/39 (26%/45%/10%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           ++LL GE PT+ Q +   + + R   +  ++ RL +    +  HPM         L    
Sbjct:  88 YILLYGETPTQEQFDKFKKTITRHTMIHEQIHRLFNGFRRDS-HPMAVLCGVTGALA--- 143

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDD-M 249
               A+   A       +    A  L++++P VAA  Y+ +       P   +    + +
Sbjct: 144 ----AFYHDALDVNNPRHRDITAYRLLSKMPTVAAMCYKYSIGQPFVYPRNDLSYAGNFL 199

Query: 250 GMRLARSLG-FELNE-FDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLN 307
            M  A     +++N   +  M    +LHADHE  N S   VR  GS+ ++P+   AAG+ 
Sbjct: 200 NMMFATPCEEYKVNPVLERAMDRIFILHADHEQ-NASTSTVRTAGSSGANPFACIAAGIA 258

Query: 308 GLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELC--WETLREGHVIPGFGHAVLR 365
            L GP HG AN+  LR L +++        + E++ E     +   +   + GFGH V +
Sbjct: 259 SLWGPAHGGANEACLRMLEEIQ--------SVEHIPEFIKRAKDKNDAFRLMGFGHRVYK 310

Query: 366 RTDPRYTAQREFALKHLP----HDEMFQLVSKLYEVV---PRVLEEQGKVKNPWPNVDQH 418
             DPR T  RE   + L     +D + ++  +L  +    P  +E     K  +PNVD +
Sbjct: 311 NYDPRATVMRETCHEVLDELGLNDSLLEVAMELERIALHDPYFIE-----KKLYPNVDFY 365

Query: 419 SGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRAL--GLPIERPKSVTTQWIREHFE 476
           SGI+L+  G + S  +TV+F ++R +G ++   W+     G+ I RP+ + T + +  F+
Sbjct: 366 SGIILKAMG-IPSTMFTVIFAIARTIGWIAH--WNEMHDGGVKIARPRQLYTGYTKRDFD 422

Query: 477 KR 478
            +
Sbjct: 423 SQ 424


ref|YP_069677.1| citrate synthase GltA [Yersinia pseudotuberculosis IP 32953]
ref|NP_670371.1| citrate synthase [Yersinia pestis KIM]
gb|AAS61298.1| citrate synthase GltA [Yersinia pestis biovar Medievalis str. 91001]
ref|NP_992421.1| citrate synthase GltA [Yersinia pestis biovar Medievalis str. 91001]
emb|CAH20382.1| citrate synthase GltA [Yersinia pseudotuberculosis IP 32953]
emb|CAC89951.1| citrate synthase GltA [Yersinia pestis CO92]
gb|AAM86622.1| citrate synthase [Yersinia pestis KIM]
ref|NP_404721.1| citrate synthase GltA [Yersinia pestis CO92]
pir||AD0136 citrate (si)-synthase (EC 4.1.3.7) GltA [imported] - Yersinia pestis (strain CO92)
(426 aa)

Score: 109 bits (272), Expect: 2.24003e-22
Length: 433, Idn/Pos/Gap = 113/193/51 (26%/44%/11%)

Query:  64 FGEEVLDACTV-NQAY----GGMRSLKAMVYETSLLDPQEGIRF-RGFSIPECQRLLPRA 117
            G +V+D  T+ ++ Y     G  S  +   + + +D  +GI   RGF         P A
Sbjct:  24 LGTDVIDVRTLGSKGYFTFDPGFTSTASCESKITYIDGDQGILLHRGF---------PIA  74

Query: 118 KPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMT 177
           + + +    E + ++LL GE PT  + ++    + R   +  ++ RL      +  HPM 
Sbjct:  75 QLAKDSTYLE-VCYILLYGETPTPEEYKTFKTTVTRHTMIHEQITRLFHGFRRDS-HPMA 132

Query: 178 QFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKH 237
                   L        A+   A       +    A  L++++P VAA  Y+ +      
Sbjct: 133 VLCGVTGALA-------AFYHDALDVNNERHREITAFRLLSKMPTVAAMCYKYSLGQPFV 185

Query: 238 VPAEKIEKVDD-MGMRLARSL-GFELNE-FDELMRLYLVLHADHEGGNVSAHAVRLVGSA 294
            P   +    + + M  +     +E+N   +  M   L+LHADHE  N S   VR  GS+
Sbjct: 186 YPRNDLSYAGNFLHMMFSTPCEKYEVNPVLERAMDRILILHADHEQ-NASTSTVRTAGSS 244

Query: 295 LSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELC--WETLRE 352
            ++P+   AAG+  L GP HG AN+  L+ L ++K        T E++ E     +   +
Sbjct: 245 GANPFACIAAGIASLWGPAHGGANEACLKMLEEIK--------TVEHIPEFIRRAKDKND 296

Query: 353 GHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNP- 411
              + GFGH V +  DPR T  RE   + L   E  +L + L EV   +  E   + +P 
Sbjct: 297 SFRLMGFGHRVYKNYDPRATVMRETCHEVL---EELKLNNSLLEVAMEL--ENIALNDPY 351

Query: 412 ------WPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLPIERPKS 465
                 +PNVD +SGI+L+  G + S+ +TV+F ++R +G ++        G+ I RP+ 
Sbjct: 352 FIEKKLYPNVDFYSGIILKAMG-IPSSMFTVIFAIARTIGWIAHWNEMHNDGIKIARPRQ 410

Query: 466 VTTQWIREHFEKR 478
           + T +    F+ +
Sbjct: 411 LYTGYTERDFQSQ 423


ref|NP_559476.1| citrate synthase [Pyrobaculum aerophilum str. IM2]
gb|AAL63658.1| citrate synthase [Pyrobaculum aerophilum str. IM2]
(409 aa)

Score: 108 bits (271), Expect: 2.49667e-22
Length: 374, Idn/Pos/Gap = 110/173/44 (29%/46%/11%)

Query:  92 SLLDPQEGIR-FRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQD 150
           S +D ++GI  +RG+ I E  RL    + S          +L+L G +PT+ ++E     
Sbjct:  37 SDIDGEKGILWYRGYRIEELARLSTYEEVS----------YLILYGRLPTKRELEDYINR  86

Query: 151 LKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLL----QHESKMAEAYAQGAPKSTFW 206
           +K+   + P  + ++  L   + HPM     AV+      +   K+ EA + G  K+   
Sbjct:  87 MKKYRELHPATVEVIRNLA--KAHPMFALEAAVAAEGAYDEDNQKLIEALSVGRYKAEEK 144

Query: 207 EYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDE 266
           E     A  L+A++P + A  YR  F  G  V    +   DD+G            E D 
Sbjct: 145 ELAYRIAEKLVAKMPTIVAYHYR--FSRGLEV----VRPRDDLGHAANFLYMMFGREPDP 198

Query: 267 L----MRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVL 322
           L    + LYL+LHADHE    S  A  +V S LSD Y S AA +  L GPLHG AN+  +
Sbjct: 199 LASRGIDLYLILHADHEV-PASTFAAHVVASTLSDLYSSVAAAIAALKGPLHGGANEMAV 257

Query: 323 RWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHL 382
           R  L++       P   + + E    T   G  + G GH V +  DPR    +EF+  ++
Sbjct: 258 RNYLEI-----GTPAKAKEIVEAA--TKPGGPKLMGVGHRVYKAYDPRAKIFKEFSRDYV 310

Query: 383 PH----DEMFQLVSKL-YEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVL 437
                   +F + S +  EV+     +Q K+   +PNVD  SGI   Y G +   ++T +
Sbjct: 311 AKFGDPQNLFAIASAIEQEVLSHPYFQQRKL---YPNVDFWSGIAFYYMG-IPYEYFTPI 366

Query: 438 FGVSRALGTLSSLV 451
           F +SR +G ++ ++
Sbjct: 367 FAMSRVVGWVAHVL 380


gb|AAM38231.1| citrate synthase [Xanthomonas axonopodis pv. citri str. 306]
ref|NP_643695.1| citrate synthase [Xanthomonas axonopodis pv. citri str. 306]
(429 aa)

Score: 108 bits (269), Expect: 4.2233e-22
Length: 355, Idn/Pos/Gap = 99/163/30 (27%/45%/8%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LL+ GE+PT  + +    ++     +   +   L    H+  HPM   + +V+ L    
Sbjct:  89 YLLMNGELPTADEFKKFDHEVTHHTMMHESLKNFLGGFRHD-AHPMAMLAGSVASLS--- 144

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDM- 249
               A+          E   + A+ LIA++P +AA  YR +       P   +  VD   
Sbjct: 145 ----AFYHDTLDLNDPEQRRQAAIRLIAKVPTLAAAAYRYSIGWPIRYPRNNLNYVDRFL 200

Query: 250 -GMRLARSLGFELNEF-DELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLN 307
             M    S   E+N    + + L  +LHADHE  N S   VRLVGS  ++PY S AAG+ 
Sbjct: 201 HMMFEVPSEPLEINPVVAKALDLLFILHADHEQ-NASTSTVRLVGSTGANPYASVAAGIT 259

Query: 308 GLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHV--IPGFGHAVLR 365
            L GP HG AN+ VL+    M E++G    T +N+     +   +     + GFGH V +
Sbjct: 260 ALWGPAHGGANEAVLK----MLEEIG----TADNVESAVAKAKDKNSSFRLMGFGHRVYK 311

Query: 366 RTDPRYTAQREFALKHLP----HDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGI 421
             DPR    RE   K L     +D + ++  KL E   +  ++    +  +PNVD +SGI
Sbjct: 312 NFDPRAKIIREMTHKVLGELGVNDPLLEVALKLEEAALK--DDYFVQRKLYPNVDFYSGI 369

Query: 422 LLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRA-LGLPIERPKSVTTQWIREHF 475
           + +    +    +TV+F ++R  G +S  +  +    + I RP+ + T + +  +
Sbjct: 370 IYKALN-IPVEMFTVMFAIARTAGWVSHWLEQQVDPEMKIGRPRQIYTGYDKRDY 423


dbj|BAD27711.1| putative Citrate synthase, glyoxysomal precursor (GCS) [Oryza sativa (japonica cultivar-group)]
(500 aa)

Score: 107 bits (268), Expect: 6.09666e-22
Length: 397, Idn/Pos/Gap = 109/180/46 (27%/45%/11%)

Query:  94 LDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLK 152
           +D  EGI R+RG+ I E            E      + +LL+ G +PT+SQ+      + 
Sbjct: 101 IDGDEGILRYRGYPIEEL----------AESSSFVEVAYLLMYGSLPTQSQLAGWEFAIS 150

Query: 153 RRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLED 212
           + +AVP  +L ++  +PH+  HPM   + A+S L      A    +G       +   + 
Sbjct: 151 QHSAVPQGLLDIIQAMPHD-AHPMGALASAMSTLSVFHPDANPALRGQDLYKSKQVRDKQ 209

Query: 213 ALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLG---FELN-EFDELM 268
            + ++ + P +AA  Y         +P   +   ++  + +  SLG   ++ N     ++
Sbjct: 210 IVRVLGKAPTIAAAAYLRLAGRPPILPTNSLSYSENF-LYMLDSLGDKEYKPNPRLARVL 268

Query: 269 RLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQM 328
            +  +LHA+HE  N S  A R + S+  D + + +  +  L GPLHG AN+ VL+ L   
Sbjct: 269 DILFILHAEHEM-NCSTAAARHLASSGVDVFTALSGAVGALYGPLHGGANEAVLKML--- 324

Query: 329 KEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMF 388
                N   + EN+ +           + GFGH V +  DPR    R+ A      +E+F
Sbjct: 325 -----NEIGSVENIPDFIEGVKNRKRKMSGFGHRVYKNYDPRAKVIRKLA------EEVF 373

Query: 389 QLVSK--LYEVV----PRVLEEQGKVKNP-WPNVDQHSGILLRYYGLVESNFYTVLFGVS 441
            +V +  L EV        L +   VK   +PNVD +SG++ R  G   + F+ VLF + 
Sbjct: 374 SIVGRDPLIEVAVALEKAALSDDYFVKRKLYPNVDFYSGLIYRAMGF-PTEFFPVLFAIP 432

Query: 442 RALGTLSSLVWDRALGLP---IERPKSVTTQ-WIREH 474
           R  G L+   W  +L  P   I RP+ V T  W+R +
Sbjct: 433 RMAGWLAH--WKESLDDPDTKIMRPQQVYTGVWLRHY 467


ref|YP_151228.1| citrate synthase [Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150]
gb|AAV77916.1| citrate synthase [Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150]
(427 aa)

Score: 107 bits (268), Expect: 6.19925e-22
Length: 359, Idn/Pos/Gap = 96/167/37 (26%/46%/10%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMT---QFSVAVSLLQ 187
           ++LL GE PT+ + +     + R   +  ++ RL      +  HPM      + A++   
Sbjct:  88 YILLYGEKPTQEEYDEFRTTVTRHTMIHEQITRLFHAFRRDS-HPMAVMCGITGALAAFY 146

Query: 188 HESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVD 247
           H+S          P+          A  L++++P +AA  Y+ +       P   +    
Sbjct: 147 HDS-----LDVNNPRHREIA-----AFRLLSKMPTMAAMCYKYSIGQPFVYPRNDLSYAG 196

Query: 248 D-MGMRLARSL-GFELNE-FDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAA 304
           + + M  +     +E+N   +  M   L+LHADHE  N S   VR  GS+ ++P+   AA
Sbjct: 197 NFLNMMFSTPCETYEVNPVLERAMDRILILHADHEQ-NASTSTVRTAGSSGANPFACIAA 255

Query: 305 GLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVL 364
           G+  L GP HG AN+  L+    M E++ +     E +R    +   +   + GFGH V 
Sbjct: 256 GIASLWGPAHGGANEAALK----MLEEISSVKHIPEFVRRA--KDKNDSFRLMGFGHRVY 309

Query: 365 RRTDPRYTAQREF---ALKHL-PHDEMFQLVSKLYEVV---PRVLEEQGKVKNPWPNVDQ 417
           +  DPR T  RE     LK L   D++ ++  +L  +    P  +E     K  +PNVD 
Sbjct: 310 KNHDPRATVMRETCHEVLKELGTKDDLLEVAMELEHIALNDPYFIE-----KKLYPNVDF 364

Query: 418 HSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLPIERPKSVTTQWIREHFE 476
           +SGI+L+  G + S+ +TV+F ++R +G ++        G+ I RP+ + T + +  F+
Sbjct: 365 YSGIILKAMG-IPSSMFTVIFAIARTVGWIAHWNEMHTDGMKIARPRQLYTGYDKRDFK 422


ref|ZP_00089489.2| COG0372: Citrate synthase [Azotobacter vinelandii]
(380 aa)

Score: 107 bits (268), Expect: 6.5175e-22
Length: 372, Idn/Pos/Gap = 99/168/56 (26%/45%/15%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LLL GE+P   Q      ++K    V  ++   L+    +  HPM      V  L    
Sbjct:  41 YLLLNGELPNADQKAKFVNNIKNHTMVHEQLKNFLNGFRRD-AHPMAVMCGVVGAL----  95

Query: 191 KMAEAYAQGAPKSTFWEYCLE---------DALTLIARLPAVAARIYRNTFHGGKHVPAE 241
                       S F+   L+          A+ L+A++P +AA +Y+ +       P  
Sbjct:  96 ------------SAFYHDSLDINDPQHREISAIRLVAKMPTLAAMVYKYSLGQPLMYPRN 143

Query: 242 KIEKVDDMGMRLARSLGFELNEFDEL----MRLYLVLHADHEGGNVSAHAVRLVGSALSD 297
            ++  ++  + +  +   E+     +    M    VLHADHE  N S   VRL GS+ ++
Sbjct: 144 DLDYAENF-LHMMFNTPCEVKPISPVLAKAMDRIFVLHADHEQ-NASTSTVRLAGSSGAN 201

Query: 298 PYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWET--LREGHV 355
           P+   AAG+  L GP HG AN+ V    L M +++G+      N+ +   +     +   
Sbjct: 202 PFACIAAGIAALWGPAHGGANEAV----LTMLDEIGD----VSNIEKFVAKAKDKNDPFK 253

Query: 356 IPGFGHAVLRRTDPRYTAQREFALKHLP----HDEMFQLVSKLYEVVPRVLEEQGKVKNP 411
           + GFGH V +  DPR    ++   + L     +D   +L  KL E+     +   K +N 
Sbjct: 254 LMGFGHRVYKNFDPRAKVMKQTCDEVLSELGINDPQLELAMKLEEIARN--DPYFKERNL 311

Query: 412 WPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP--IERPKSVTTQ 469
           +PNVD +SGI+L+  G + ++ +TV+F ++R +G +S   W   L  P  I RP+ + T 
Sbjct: 312 YPNVDFYSGIILKAIG-IPTSMFTVIFALARTVGWISH--WKEMLSGPYKIGRPRQLYTG 368

Query: 470 WIREHF---EKR 478
           + +  +   EKR
Sbjct: 369 YEKRDYISVEKR 380


gb|AAA25769.1| citrate synthase
(428 aa)

Score: 107 bits (268), Expect: 6.85209e-22
Length: 358, Idn/Pos/Gap = 98/165/37 (27%/46%/10%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LLL GE+PT +Q E     +K    V  ++    +    +  HPM      +  L    
Sbjct:  88 YLLLNGELPTAAQKEQFVGTIKNHTMVHEQLKTFFNGFRRD-AHPMAVMCGVIGALS--- 143

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMG 250
               A+   +   T  ++    A  LIA++P +AA +Y+ +       P   +   ++  
Sbjct: 144 ----AFYHDSLDITNPKHRQVSAHRLIAKMPTIAAMVYKYSKGEPMMYPRNDLNYAENF- 198

Query: 251 MRLARSLGFELNEFDEL----MRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGL 306
           + +  +   E      +    M    +LHADHE  N S   VRL GS+ ++P+   A+G+
Sbjct: 199 LHMMFNTPCETKPISPVLAKAMDRIFILHADHEQ-NASTSTVRLAGSSGANPFACIASGI 257

Query: 307 NGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRR 366
             L GP HG AN+ VLR L ++ + + N     E  ++       +   + GFGH V + 
Sbjct: 258 AALWGPAHGGANEAVLRMLDEIGD-VSNIDKFVEKAKD-----KNDPFKLMGFGHRVYKN 311

Query: 367 TDPRYTAQREF---ALKHLP-HDEMFQLVSKLYEVV---PRVLEEQGKVKNPWPNVDQHS 419
            DPR    ++     L+ L  +D   +L  KL E+    P  +E     +N +PNVD +S
Sbjct: 312 FDPRAKVMKQTCDEVLQELGINDPQLELAMKLEEIARHDPYFVE-----RNLYPNVDFYS 366

Query: 420 GILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP--IERPKSVTTQWIREHF 475
           GI+L+  G + ++ +TV+F ++R +G +S   W   L  P  I RP+ + T   +  F
Sbjct: 367 GIILKAIG-IPTSMFTVIFALARTVGWISH--WQEMLSGPYKIGRPRQLYTGHTQRDF 421


pir||YKPSCA citrate (si)-synthase (EC 4.1.3.7) - Pseudomonas aeruginosa
(428 aa)

Score: 107 bits (267), Expect: 8.3017e-22
Length: 358, Idn/Pos/Gap = 98/165/37 (27%/46%/10%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LLL GE+PT +Q E     +K    V  ++    +    +  HPM      +  L    
Sbjct:  88 YLLLNGELPTAAQKEQFVGTIKNHTMVHEQLKTFFNGFRRD-AHPMAVMCGVIGALS--- 143

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMG 250
               A+   +   T  ++    A  LIA++P +AA +Y+ +       P   +   ++  
Sbjct: 144 ----AFYHDSLDITNPKHREVSAHRLIAKMPTIAAMVYKYSKGEPMMYPRNDLNYAENF- 198

Query: 251 MRLARSLGFELNEFDEL----MRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGL 306
           + +  +   E      +    M    +LHADHE  N S   VRL GS+ ++P+   A+G+
Sbjct: 199 LHMMFNTPCETKPISPVLAKAMDRIFILHADHEQ-NASTSTVRLAGSSGANPFACIASGI 257

Query: 307 NGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRR 366
             L GP HG AN+ VLR L ++ + + N     E  ++       +   + GFGH V + 
Sbjct: 258 AALWGPAHGGANEAVLRMLDEIGD-VSNIDKFVEKAKD-----KNDPFKLMGFGHRVYKN 311

Query: 367 TDPRYTAQREF---ALKHLP-HDEMFQLVSKLYEVV---PRVLEEQGKVKNPWPNVDQHS 419
            DPR    ++     L+ L  +D   +L  KL E+    P  +E     +N +PNVD +S
Sbjct: 312 FDPRAKVMKQTCDEVLQELGINDPQLELAMKLEEIARHDPYFVE-----RNLYPNVDFYS 366

Query: 420 GILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP--IERPKSVTTQWIREHF 475
           GI+L+  G + ++ +TV+F ++R +G +S   W   L  P  I RP+ + T   +  F
Sbjct: 367 GIILKAIG-IPTSMFTVIFALARTVGWISH--WQEMLSGPYKIGRPRQLYTGHTQRDF 421


ref|NP_638581.1| citrate synthase [Xanthomonas campestris pv. campestris str. ATCC 33913]
gb|AAM42505.1| citrate synthase [Xanthomonas campestris pv. campestris str. ATCC 33913]
(429 aa)

Score: 107 bits (267), Expect: 8.51212e-22
Length: 355, Idn/Pos/Gap = 98/163/30 (27%/45%/8%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LL+ GE+PT  + +    ++     +   +   L    H+  HPM   + +V+ L    
Sbjct:  89 YLLMNGELPTADEFKKFDHEVTHHTMMHESLKNFLGGFRHD-AHPMAMLAGSVASLS--- 144

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDM- 249
               A+          E   + A+ LIA++P +AA  YR +       P   +  VD   
Sbjct: 145 ----AFYHDTLDLNDPEQRRQAAIRLIAKVPTLAAAAYRYSIGWPIRYPRNNLNYVDRFL 200

Query: 250 -GMRLARSLGFELNEF-DELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLN 307
             M    S   E+N    + + L  +LHADHE  N S   VRLVGS  ++PY S AAG+ 
Sbjct: 201 HMMFEVPSEPLEINPVVAKALDLLFILHADHEQ-NASTSTVRLVGSTGANPYASVAAGIT 259

Query: 308 GLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHV--IPGFGHAVLR 365
            L GP HG AN+ VL+    M E++G    T +N+     +   +     + GFGH V +
Sbjct: 260 ALWGPAHGGANEAVLK----MLEEIG----TADNVESAVAKAKDKNSSFRLMGFGHRVYK 311

Query: 366 RTDPRYTAQREFALKHLP----HDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGI 421
             DPR    RE   K L     +D + ++  KL E   +  ++    +  +PNVD +SG+
Sbjct: 312 NFDPRAKIIREMTHKVLGELGVNDPLLEVALKLEEAALK--DDYFVQRKLYPNVDFYSGL 369

Query: 422 LLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRA-LGLPIERPKSVTTQWIREHF 475
           + +    +    +TV+F ++R  G +S  +  +    + I RP+ + T + +  +
Sbjct: 370 IYKALN-IPVEMFTVMFAIARTAGWVSHWLEQQVDPEMKIGRPRQIYTGYDKRDY 423


gb|AAL57051.1| citrate synthase [Wolbachia pipientis]
(413 aa)

Score: 107 bits (266), Expect: 9.647e-22
Length: 359, Idn/Pos/Gap = 96/175/34 (26%/48%/9%)

Query:  92 SLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQD 150
           + +D  EG+ ++RG +I +            E      +++LLL G++P+  Q +     
Sbjct:  58 TFIDGDEGVLKYRGHNIADL----------AENNNFTAVIYLLLYGKLPSSEQHKKFLLK 107

Query: 151 LKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCL 210
           ++  + V  +V  ++   P +  HPM   S+ V+     + ++ +Y +   K+   E  L
Sbjct: 108 IQESSKVSEQVTNVIKAFP-KTAHPM---SILVACF---ANLSASYHEMHGKNVNGED-L 159

Query: 211 EDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRL 270
           +  ++ IA++PA+ A IYR+  +  + + A       +  + +          F + +  
Sbjct: 160 DFGISAIAKVPAIVAMIYRH-INNQEFINANNKLSYSENFLNMIFGSAVNNTLFVKALDK 218

Query: 271 YLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKE 330
              LHADHE  N S  AVRLVGSA S+ + S +AG+  L GP HG AN+ V+  L ++ E
Sbjct: 219 IFTLHADHEQ-NASTAAVRLVGSAGSNLFASLSAGVATLWGPAHGGANEAVINMLKEI-E 276

Query: 331 KLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRY----TAQREFALKHLPHDE 386
           + G+     E  ++      ++   + GFGH V +  DPR      A  E   K   ++E
Sbjct: 277 QSGDVDRFIEKAKD-----DKDPFKLMGFGHRVYKNYDPRALILKDACHEILSKLEQNNE 331

Query: 387 MFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALG 445
           + ++  KL E+  +  +E    +  +PNVD +SGI++   G + S+ +T +F ++R  G
Sbjct: 332 LLEIAKKLEEIALK--DEYFITRKLYPNVDFYSGIIMNAIG-IPSSMFTPIFALARTTG 387


gb|AAL19674.1| citrate synthase [Salmonella typhimurium LT2]
gb|AAC12779.1| citrate synthase [Salmonella typhimurium]
ref|NP_459715.1| citrate synthase [Salmonella typhimurium LT2]
sp|O68883|CISY_SALTY Citrate synthase
(427 aa)

Score: 107 bits (266), Expect: 1.07523e-21
Length: 359, Idn/Pos/Gap = 96/167/37 (26%/46%/10%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMT---QFSVAVSLLQ 187
           ++LL GE PT+ + +     + R   +  ++ RL      +  HPM      + A++   
Sbjct:  88 YILLYGEKPTQEEYDEFRTTVTRHTMIHEQITRLFHAFRRDS-HPMAVMCGITGALAAFY 146

Query: 188 HESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVD 247
           H+S          P+          A  L++++P +AA  Y+ +       P   +    
Sbjct: 147 HDS-----LDVNNPRHREIA-----AFRLLSKMPTMAAMCYKYSIGQPFVYPRNDLSYAG 196

Query: 248 D-MGMRLARSL-GFELNE-FDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAA 304
           + + M  +     +E+N   +  M   L+LHADHE  N S   VR  GS+ ++P+   AA
Sbjct: 197 NFLNMMFSTPCETYEVNPVLERAMDRILILHADHEQ-NASTSTVRTAGSSGANPFACIAA 255

Query: 305 GLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVL 364
           G+  L GP HG AN+  L+    M E++ +     E +R    +   +   + GFGH V 
Sbjct: 256 GIASLWGPAHGGANEAALK----MLEEISSVKHIPEFVRRA--KDKNDSFRLMGFGHRVY 309

Query: 365 RRTDPRYTAQREF---ALKHL-PHDEMFQLVSKLYEVV---PRVLEEQGKVKNPWPNVDQ 417
           +  DPR T  RE     LK L   D++ ++  +L  +    P  +E     K  +PNVD 
Sbjct: 310 KNYDPRATVMRETCHEVLKELGTKDDLLEVAMELEHIALNDPYFIE-----KKLYPNVDF 364

Query: 418 HSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLPIERPKSVTTQWIREHFE 476
           +SGI+L+  G + S+ +TV+F ++R +G ++        G+ I RP+ + T + +  F+
Sbjct: 365 YSGIILKAMG-IPSSMFTVIFAMARTVGWIAHWNEMHTDGMKIARPRQLYTGYDKRDFK 422


ref|YP_215723.1| citrate synthase [Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67]
gb|AAX64642.1| citrate synthase [Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67]
(427 aa)

Score: 107 bits (266), Expect: 1.13042e-21
Length: 359, Idn/Pos/Gap = 96/167/37 (26%/46%/10%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMT---QFSVAVSLLQ 187
           ++LL GE PT+ + +     + R   +  ++ RL      +  HPM      + A++   
Sbjct:  88 YILLYGEKPTQEEYDEFRTTVTRHTMIHEQITRLFHAFRRDS-HPMAVMCGITGALAAFY 146

Query: 188 HESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVD 247
           H+S          P+          A  L++++P +AA  Y+ +       P   +    
Sbjct: 147 HDS-----LDVNNPRHREIA-----AFRLLSKMPTMAAMCYKYSIGQPFVYPRNDLSYAG 196

Query: 248 D-MGMRLARSL-GFELNE-FDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAA 304
           + + M  +     +E+N   +  M   L+LHADHE  N S   VR  GS+ ++P+   AA
Sbjct: 197 NFLNMMFSTPCETYEVNPVLERAMDRILILHADHEQ-NASTSTVRTAGSSGANPFACIAA 255

Query: 305 GLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVL 364
           G+  L GP HG AN+  L+    M E++ +     E +R    +   +   + GFGH V 
Sbjct: 256 GIASLWGPAHGGANEAALK----MLEEISSVKHIPEFVRRA--KDKNDSFRLMGFGHRVY 309

Query: 365 RRTDPRYTAQREF---ALKHL-PHDEMFQLVSKLYEVV---PRVLEEQGKVKNPWPNVDQ 417
           +  DPR T  RE     LK L   D++ ++  +L  +    P  +E     K  +PNVD 
Sbjct: 310 KNYDPRATVMRETCHEVLKELGTKDDLLEVAMELEHIALNDPYFIE-----KKLYPNVDF 364

Query: 418 HSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLPIERPKSVTTQWIREHFE 476
           +SGI+L+  G + S+ +TV+F ++R +G ++        G+ I RP+ + T + +  F+
Sbjct: 365 YSGIILKAMG-IPSSMFTVIFAMARTVGWIAHWNEMHTDGMKIARPRQLYTGYDKRDFK 422


pdb|1OWC|B Chain B, Three Dimensional Structure Analysis Of The R109l Variant Of The Type Ii Citrate Synthase From E. Coli
pdb|1OWC|A Chain A, Three Dimensional Structure Analysis Of The R109l Variant Of The Type Ii Citrate Synthase From E. Coli
pdb|1OWB|B Chain B, Three Dimensional Structure Analysis Of The Variant R109l Nadh Complex Of Type Ii Citrate Synthase From E. Coli
pdb|1OWB|A Chain A, Three Dimensional Structure Analysis Of The Variant R109l Nadh Complex Of Type Ii Citrate Synthase From E. Coli
(427 aa)

Score: 106 bits (265), Expect: 1.21858e-21
Length: 359, Idn/Pos/Gap = 96/166/37 (26%/46%/10%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMT---QFSVAVSLLQ 187
           ++LL GE PT+ Q +     +     +  ++ RL      +  HPM      + A++   
Sbjct:  88 YILLNGEKPTQEQYDEFKTTVTLHTMIHEQITRLFHAFRRDS-HPMAVMCGITGALAAFY 146

Query: 188 HESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVD 247
           H+S          P+          A  L++++P +AA  Y+ +       P   +    
Sbjct: 147 HDS-----LDVNNPRHREIA-----AFRLLSKMPTMAAMCYKYSIGQPFVYPRNDLSYAG 196

Query: 248 D-MGMRLARSLG-FELNE-FDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAA 304
           + + M  +     +E+N   +  M   L+LHADHE  N S   VR  GS+ ++P+   AA
Sbjct: 197 NFLNMMFSTPCEPYEVNPILERAMDRILILHADHEQ-NASTSTVRTAGSSGANPFACIAA 255

Query: 305 GLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVL 364
           G+  L GP HG AN+  L+    M E++ +     E  R    +   +   + GFGH V 
Sbjct: 256 GIASLWGPAHGGANEAALK----MLEEISSVKHIPEFFRRA--KDKNDSFRLMGFGHRVY 309

Query: 365 RRTDPRYTAQREF---ALKHL-PHDEMFQLVSKLYEVV---PRVLEEQGKVKNPWPNVDQ 417
           +  DPR T  RE     LK L   D++ ++  +L  +    P  +E     K  +PNVD 
Sbjct: 310 KNYDPRATVMRETCHEVLKELGTKDDLLEVAMELENIALNDPYFIE-----KKLYPNVDF 364

Query: 418 HSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLPIERPKSVTTQWIREHFE 476
           +SGI+L+  G + S+ +TV+F ++R +G ++      + G+ I RP+ + T + +  F+
Sbjct: 365 YSGIILKAMG-IPSSMFTVIFAMARTVGWIAHWSEMHSDGMKIARPRQLYTGYEKRDFK 422


ref|YP_047431.1| citrate synthase [Acinetobacter sp. ADP1]
emb|CAG69609.1| citrate synthase [Acinetobacter sp. ADP1]
(424 aa)

Score: 106 bits (265), Expect: 1.34691e-21
Length: 369, Idn/Pos/Gap = 103/164/74 (27%/44%/20%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LLL GE+PT  Q +     ++    V  +V R  +    +  HPM      V  L    
Sbjct:  90 YLLLNGELPTPEQKQEFDAKVRNHTMVHDQVSRFFNGFRRD-AHPMAIMVGVVGAL---- 144

Query: 191 KMAEAYAQGAPKSTFW--EYCLED-------ALTLIARLPAVAARIYR------------ 229
                       S F+  +  +ED       A+ LIA++P +AA  Y+            
Sbjct: 145 ------------SAFYHNQLNIEDVNHREITAIRLIAKIPTLAAWSYKYTVGQPFIYPRN 192

Query: 230 ------NTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVLHADHEGGNV 283
                 N  H     PA++  KV+ +   LA++           M     LHADHE  N 
Sbjct: 193 DLGYAENFLHMMFATPADRDYKVNPI---LAKA-----------MDRIFTLHADHEQ-NA 237

Query: 284 SAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLR 343
           S   VRL GS  ++PY   AAG++ L GP HG AN+ VL+    M +++G    T EN+ 
Sbjct: 238 STSTVRLAGSTGANPYACIAAGISALWGPAHGGANEAVLK----MLDEIG----TVENVA 289

Query: 344 ELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLP----HDEMFQLVSKLYEVVP 399
               +   +   + GFGH V +  DPR    +E   + L     +D   +L  +L  +  
Sbjct: 290 GFMEKVKTKEVKLMGFGHRVYKNFDPRAKVMKETCDEVLAALGINDPQLELAMELERIA- 348

Query: 400 RVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP 459
            + +E    +N +PNVD +SGI+L+  G + +  +TV+F ++R +G +S  +   +    
Sbjct: 349 -LSDEYFIKRNLYPNVDFYSGIILKAIG-IPTEMFTVIFALARTVGWISHWLEMHSAPYK 406

Query: 460 IERPKSVTT 468
           I RP+ + T
Sbjct: 407 IGRPRQLYT 415


ref|YP_056131.1| citrate synthase [Propionibacterium acnes KPA171202]
gb|AAT83173.1| citrate synthase [Propionibacterium acnes KPA171202]
(436 aa)

Score: 106 bits (265), Expect: 1.41605e-21
Length: 432, Idn/Pos/Gap = 116/190/59 (26%/43%/13%)

Query:  65 GEEVLDACTVNQAYGGMRSLKAMVYET-------SLLDPQEGI-RFRGFSIPECQRLLPR 116
           G+ V+D   + Q  GG+ +       T       S +D +EG+  +RG         LP 
Sbjct:  34 GDRVIDISNLRQLTGGVTTFDPAFANTASCRSAISWIDGEEGVLTYRG---------LPI  84

Query: 117 AKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPM 176
              + E+       WLL+ G +PTE+Q +     L   +A+   +    +  P    HPM
Sbjct:  85 ETLAKERVSFVETAWLLIFGHLPTEAQRDDFRNRLTEYSALHRSMNLHFNAFP-PNGHPM 143

Query: 177 TQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGK 236
              S  ++ +    +         P+ T  E   + A  L++++  +AA  Y+ +     
Sbjct: 144 AIMSSMINAMSTHDR---------PRITDEESFTDAAAKLMSKVRTIAAASYKASIGEPA 194

Query: 237 HVPAEKIEKVDDMGMRLARSLGFELNEFDEL----MRLYLVLHADHEGGNVSAHAVRLVG 292
             P   ++ V++  M +  SL +   E D +    + L+ VLHADH G N S   VR+VG
Sbjct: 195 IYPRYDLKYVENF-MHMMFSLPYRAYEPDPVAARALNLFFVLHADH-GQNCSTSTVRMVG 252

Query: 293 SALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLRE 352
           S+ ++ + S +AG+  L G  HG AN   +  L    +++ N  +T    R+   +    
Sbjct: 253 SSGANLFTSCSAGVCALWGDRHGGANVNAVLAL----QRIRNSGLTP---RQYLAKAKDS 305

Query: 353 GHVIPGFGHAVLRRTDPRYTAQREFA-----LKHLPHDEMFQLVSKLYEVVPRVLEEQGK 407
           G  I GFGH V R  DPR    R          H P D +  +  +L E V  + ++   
Sbjct: 306 GERISGFGHRVYRNWDPRARIFRSVVGPLLDTMHKP-DPLLDVAMELEEAV--LADDYFI 362

Query: 408 VKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPK 464
            +  +PNVD +SGI+LR  G +  N +TV+F + R  G ++   W      P   I RP+
Sbjct: 363 ERRLYPNVDFYSGIVLRALG-IPLNMFTVMFAIGRMAGWIAH--WKEVFEDPTTRISRPR 419

Query: 465 S-----VTTQWI 471
                 V+T W+
Sbjct: 420 ELYDGPVSTPWV 431


emb|CAB14874.1| citrate synthase II [Bacillus subtilis subsp. subtilis str. 168]
ref|NP_390792.1| citrate synthase II [Bacillus subtilis subsp. subtilis str. 168]
sp|P39120|CISY2_BACSU Citrate synthase II
gb|AAC00345.1| citrate synthase subunit II [Bacillus subtilis]
(372 aa)

Score: 106 bits (264), Expect: 1.6183e-21
Length: 333, Idn/Pos/Gap = 97/152/40 (29%/45%/12%)

Query: 127 EGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLL 186
           E +++LL    +P + ++E + Q L + AAVP E++        E +HPM     A+SLL
Sbjct:  42 EEIIYLLWHLRLPNKKELEELKQQLAKEAAVPQEIIEHFKSYSLENVHPMAALRTAISLL 101

Query: 187 QHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKV 246
                 A+      P++ +       A+ L A++P + A   R     G     E +E  
Sbjct: 102 GLLDSEADTM---NPEANY-----RKAIRLQAKVPGLVAAFSR--IRKG----LEPVEPR 147

Query: 247 DDMGMRLARSLGFELNEFD------ELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYL 300
           +D G  +A +  + LN  +      E     L+LHADHE  N S    R+  + LSD Y 
Sbjct: 148 EDYG--IAENFLYTLNGEEPSPIEVEAFNKALILHADHE-LNASTFTARVCVATLSDIYS 204

Query: 301 SFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFG 360
              A +  L GPLHG AN+ V++ L ++ E         EN        L +   I GFG
Sbjct: 205 GITAAIGALKGPLHGGANEGVMKMLTEIGE--------VENAEPYIRAKLEKKEKIMGFG 256

Query: 361 HAVLRRTDPRYTAQREFA--LKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQH 418
           H V +  DPR    +E +  L +L  +      SK YE+  R+ +     K   PNVD +
Sbjct: 257 HRVYKHGDPRAKHLKEMSKRLTNLTGE------SKWYEMSIRIEDIVTSEKKLPPNVDFY 310

Query: 419 SGILLRYYGLVESNFYTVLFGVSRALGTLSSLV 451
           S  +    G ++ + +T +F VSR  G L+ ++
Sbjct: 311 SASVYHSLG-IDHDLFTPIFAVSRMSGWLAHIL 342


pdb|1NXE|B Chain B, A Novel Nadh Allosteric Regulator Site Is Found On The Surface Of The Hexameric Type Ii Phe383ala Variant Of Citrate Synthase
pdb|1NXE|A Chain A, A Novel Nadh Allosteric Regulator Site Is Found On The Surface Of The Hexameric Type Ii Phe383ala Variant Of Citrate Synthase
pdb|1NXG|B Chain B, The F383a Variant Of Type Ii Citrate Synthase Complexed With Nadh
pdb|1NXG|A Chain A, The F383a Variant Of Type Ii Citrate Synthase Complexed With Nadh
(427 aa)

Score: 106 bits (264), Expect: 1.65932e-21
Length: 359, Idn/Pos/Gap = 96/166/37 (26%/46%/10%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMT---QFSVAVSLLQ 187
           ++LL GE PT+ Q +     + R   +  ++ RL      +  HPM      + A++   
Sbjct:  88 YILLNGEKPTQEQYDEFKTTVTRHTMIHEQITRLFHAFRRDS-HPMAVMCGITGALAAFY 146

Query: 188 HESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVD 247
           H+S          P+          A  L++++P +AA  Y+ +       P   +    
Sbjct: 147 HDS-----LDVNNPRHREIA-----AFRLLSKMPTMAAMCYKYSIGQPFVYPRNDLSYAG 196

Query: 248 D-MGMRLARSLG-FELNE-FDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAA 304
           + + M  +     +E+N   +  M   L+LHADHE  N S   VR  GS+ ++P+   AA
Sbjct: 197 NFLNMMFSTPCEPYEVNPILERAMDRILILHADHEQ-NASTSTVRTAGSSGANPFACIAA 255

Query: 305 GLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVL 364
           G+  L GP HG AN+  L+    M E++ +     E  R    +   +   + GFGH V 
Sbjct: 256 GIASLWGPAHGGANEAALK----MLEEISSVKHIPEFFRRA--KDKNDSFRLMGFGHRVY 309

Query: 365 RRTDPRYTAQREF---ALKHL-PHDEMFQLVSKLYEVV---PRVLEEQGKVKNPWPNVDQ 417
           +  DPR T  RE     LK L   D++ ++  +L  +    P  +E     K  +PNVD 
Sbjct: 310 KNYDPRATVMRETCHEVLKELGTKDDLLEVAMELENIALNDPYFIE-----KKLYPNVDF 364

Query: 418 HSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLPIERPKSVTTQWIREHFE 476
           +SGI+L+  G + S+ +TV+  ++R +G ++      + G+ I RP+ + T + +  F+
Sbjct: 365 YSGIILKAMG-IPSSMFTVIAAMARTVGWIAHWSEMHSDGMKIARPRQLYTGYEKRDFK 422


ref|ZP_00381042.1| COG0372: Citrate synthase [Brevibacterium linens BL2]
(427 aa)

Score: 106 bits (264), Expect: 1.7445e-21
Length: 349, Idn/Pos/Gap = 98/162/32 (28%/46%/9%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LL+ GE+PT+ Q ++    L+    V  ++ R     P++        +   +L     
Sbjct:  87 YLLIHGELPTQEQYDAFDGRLRGHTIVHEDLRRFFRAFPYDAHPMPMVAAAVAALSTFYQ 146

Query: 191 KMAEAYAQG-APKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDM 249
              + + +G    STF          L+A++P +AA  +R         P   +  V++ 
Sbjct: 147 DDLDVFDEGQVDTSTF---------RLLAKMPTIAALAHRKNMGLPVIHPDNSLSLVENF 197

Query: 250 GMRLARSLGFELNEFDEL----MRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAG 305
            +R+   +  E  E D L    M    +LHADHE  N S   VRLVGS+ ++ + S +AG
Sbjct: 198 -LRVNFGVPAEDYEPDPLAVKAMDQLFILHADHEQ-NCSTSTVRLVGSSQANLFQSISAG 255

Query: 306 LNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLR 365
           +N LAGPLHG AN  V    L M E++       E   E   +   +G  + GFGH V +
Sbjct: 256 VNALAGPLHGGANSAV----LTMLEEISASDDGPEKFMERV-KNKEDGVRLMGFGHRVYK 310

Query: 366 RTDPRYTAQREFALKHLPH---DEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGIL 422
             DPR    ++ A + L     D + ++  KL E+   + ++    +  +PNVD ++G++
Sbjct: 311 NYDPRAKIIKKTADEVLARSGGDPLLEVAQKLEEIA--LADDYFVERKLYPNVDFYTGLI 368

Query: 423 LRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPKSVTT 468
            +  G   +N +TVLF V R  G ++   W   +  P   I RP+ + T
Sbjct: 369 YKALGF-PTNMFTVLFAVGRLPGWIAQ--WREMINDPETKIGRPRQIYT 414


sp|P49299|CYSZ_CUCMA Citrate synthase, glyoxysomal precursor (GCS)
pir||S53007 citrate synthase - cucurbit
dbj|BAA07328.1| glyoxysomal citrate synthase [Cucurbita cv. Kurokawa Amakuri]
(516 aa)

Score: 106 bits (264), Expect: 1.81882e-21
Length: 399, Idn/Pos/Gap = 109/181/46 (27%/45%/11%)

Query:  92 SLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQD 150
           S +D   GI R+RG+ I E            E      + +LL+ G +P++SQ+      
Sbjct: 115 SYIDGDLGILRYRGYPIEEL----------AESSTYVEVAYLLMYGNLPSQSQLADWEFA 164

Query: 151 LKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCL 210
           + + +AVP  ++ ++  +PH+  HPM     A+S L      A    +G       +   
Sbjct: 165 ISQHSAVPQGLVDIIQAMPHD-AHPMGVLVSAMSALSVFHPDANPALRGQDLYKSKQVRD 223

Query: 211 EDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLG---FELN-EFDE 266
           +    +I + P +AA  Y         +P+  +   ++  + +  SLG   ++ N     
Sbjct: 224 KQIARIIGKAPTIAAAAYLRLAGRPPVLPSSNLSYSENF-LYMLDSLGNRSYKPNPRLAR 282

Query: 267 LMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLL 326
           ++ +  +LHA+HE  N S  A R + S+  D + + +  +  L GPLHG AN+ VL+ L 
Sbjct: 283 VLDILFILHAEHEM-NCSTSAARHLASSGVDVFTALSGAVGALYGPLHGGANEAVLKMLS 341

Query: 327 QMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDE 386
           ++         T  N+ E           + GFGH V +  DPR    R+ A      +E
Sbjct: 342 EIG--------TVNNIPEFIEGVKNRKRKMSGFGHRVYKNYDPRAKVIRKLA------EE 387

Query: 387 MFQLVSK--LYEVV----PRVLEEQGKVKNP-WPNVDQHSGILLRYYGLVESNFYTVLFG 439
           +F +V +  L EV        L ++  VK   +PNVD +SG++ R  G     F+TVLF 
Sbjct: 388 VFSIVGRDPLIEVAVALEKAALSDEYFVKRKLYPNVDFYSGLIYRAMGF-PPEFFTVLFA 446

Query: 440 VSRALGTLSSLVWDRALGLP---IERPKSV-TTQWIREH 474
           + R  G L+   W  +L  P   I RP+ V T +W+R +
Sbjct: 447 IPRMAGYLAH--WRESLDDPDTKIIRPQQVYTGEWLRHY 483


ref|ZP_00172404.2| COG0372: Citrate synthase [Methylobacillus flagellatus KT]
(430 aa)

Score: 106 bits (264), Expect: 1.86492e-21
Length: 398, Idn/Pos/Gap = 113/185/46 (28%/46%/11%)

Query:  92 SLLDPQEGIRF-RGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQD 150
           + +D +EG+ F RG+ I +            E      + +LL+ GE+P   Q E     
Sbjct:  59 TFIDGEEGLLFYRGYPIEQL----------AEHSDFMEVSYLLIYGELPNAEQKEKFTNT 108

Query: 151 LKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKM-AEAYAQGAPKSTFWEYC 209
           + R + V  ++  +      +  HPM   +V V ++   S    EA     P++   E+ 
Sbjct: 109 ITRHSMVHDQLTHIFRGFRRD-AHPM---AVMVGVVGSMSAFYHEAIDVSDPRNR--EFA 162

Query: 210 LEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDD-MGMRLARSL-GFELNE-FDE 266
              A  L+A++P +AA  Y+         P  +    ++ M M  A     +E N    +
Sbjct: 163 ---AHRLLAKVPTIAAWSYKYNVGQPFMYPKNRFNYAENFMHMMFATPCEDYEPNPVLAK 219

Query: 267 LMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLL 326
                L+LHADHE  N S   VRL GS+ ++P+   AAG+  L GP HG AN+  L+   
Sbjct: 220 AFERILILHADHEQ-NASTSTVRLAGSSGANPFACVAAGIASLWGPAHGGANEATLK--- 275

Query: 327 QMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPH-- 384
            M E++G+     E ++    +T  +   + GFGH V R  DPR    R+   + L    
Sbjct: 276 -MLEEIGDISRIGEYIKRAKDKT--DSFRLMGFGHRVYRNMDPRAAIMRQTCHQVLDELG 332

Query: 385 ---DEMFQLVSKLYEVVPRVLEEQGKV-KNPWPNVDQHSGILLRYYGLVESNFYTVLFGV 440
              D MF+L  +L ++    LE++  V +  +PNVD +SGI++R  G+  S F T +F +
Sbjct: 333 LNDDPMFKLALELEKI---ALEDEYFVSRRLYPNVDFYSGIVMRAMGIPNSMF-TAIFAL 388

Query: 441 SRALGTLSSLVWDRALGLP---IERPKSVTTQWIREHF 475
           +R +G ++   W+  +  P   I RP+ + T   R  F
Sbjct: 389 ARTVGWVAQ--WNEMMSDPGSKIGRPRQLYTGPERRDF 424


ref|YP_141626.1| citrate synthase [Streptococcus thermophilus CNRZ1066]
ref|YP_139714.1| citrate synthase [Streptococcus thermophilus LMG 18311]
gb|AAV62811.1| citrate synthase [Streptococcus thermophilus CNRZ1066]
gb|AAV60899.1| citrate synthase [Streptococcus thermophilus LMG 18311]
(374 aa)

Score: 106 bits (264), Expect: 1.88055e-21
Length: 327, Idn/Pos/Gap = 91/155/30 (27%/47%/9%)

Query: 127 EGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLR--LLDELPHERMHPMTQFSVAVS 184
           E +++LL  G +PT+ +++    +L++   +   V +  L+   PH  +HPM+     VS
Sbjct:  45 EEVIYLLWNGHLPTQMELKYFEAELRKNYDISDAVEQCILIQSRPH--LHPMSVLRSTVS 102

Query: 185 LLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIE 244
           LL   +  AE  +         E   + ++ L+A+LP +     R     GK +P +  +
Sbjct: 103 LLGVYNVDAEERSM--------EAVYQQSIELMAKLPTIITTFAR--LRTGK-MPLKPRK 151

Query: 245 KVDDMGMRLARSLGFELNEFD-ELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFA 303
            +      L    G E +E + E M   L+LHADHE  N S  A R+  S L+D Y    
Sbjct: 152 DLGFAANFLYMLNGVEPSEIEIEAMNKTLILHADHEL-NASTFAARVCASTLTDIYSCVT 210

Query: 304 AGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAV 363
             +  L GPLHG AN+ V   L +++E        + ++     E L     I GFGH V
Sbjct: 211 TAIGALKGPLHGGANERVFDMLKEVRE--------SGDVNAYLQEKLDSKEKIMGFGHRV 262

Query: 364 LRRTDPRYTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILL 423
            ++ DPR    R+ A K     E  +  +K  E+   + +++G +    PNVD +S  + 
Sbjct: 263 YKKKDPREIFLRDMAKKLTEGTENEEFFNKSQEIEEFMRDKKGLI----PNVDFYSATVY 318

Query: 424 RYYGLVESNFYTVLFGVSRALGTLSSL 450
              G ++S+ +T++F +SR  G ++ +
Sbjct: 319 HTLG-IDSDIFTLIFAMSRVAGWIAHI 344


ref|NP_805900.1| citrate synthase [Salmonella enterica subsp. enterica serovar Typhi Ty2]
ref|NP_455286.1| citrate synthase [Salmonella enterica subsp. enterica serovar Typhi str. CT18]
emb|CAD05192.1| citrate synthase [Salmonella enterica subsp. enterica serovar Typhi]
gb|AAO69760.1| citrate synthase [Salmonella enterica subsp. enterica serovar Typhi Ty2]
pir||AF0590 citrate synthase [imported] - Salmonella enterica subsp. enterica serovar Typhi (strain CT18)
(427 aa)

Score: 106 bits (264), Expect: 1.8963e-21
Length: 359, Idn/Pos/Gap = 96/166/37 (26%/46%/10%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMT---QFSVAVSLLQ 187
           ++LL GE PT+ + +     + R   +  ++ RL      +  HPM      + A++   
Sbjct:  88 YILLYGEKPTQEEYDEFRTTVTRHTMIHEQITRLFHAFRRDS-HPMAVMCGITGALAAFY 146

Query: 188 HESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVD 247
           H+S          P+          A  L++++P +AA  Y+ +       P   +    
Sbjct: 147 HDS-----LDVNNPRHREIA-----AFRLLSKMPTMAAMCYKYSIGQPFVYPRNDLSYAG 196

Query: 248 D-MGMRLARSL-GFELNE-FDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAA 304
           + + M  +     +E+N   +  M   L+LHADHE  N S   VR  GS+ ++P+   AA
Sbjct: 197 NFLNMMFSTPCETYEVNPVLERAMDRILILHADHEQ-NASTSTVRTAGSSGANPFACIAA 255

Query: 305 GLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVL 364
           G+  L GP HG AN+  L+    M E++ +     E +R    +   +   + GFGH V 
Sbjct: 256 GIASLWGPAHGGANEAALK----MLEEISSVKHIPEFVRRA--KDKNDSFRLMGFGHRVY 309

Query: 365 RRTDPRYTAQREF---ALKHL-PHDEMFQLVSKLYEVV---PRVLEEQGKVKNPWPNVDQ 417
           +  DPR T  RE     LK L   D++ ++   L  +    P  +E     K  +PNVD 
Sbjct: 310 KNYDPRATVMRETCHEVLKELGTKDDLLEVAMGLEHIALNDPYFIE-----KKLYPNVDF 364

Query: 418 HSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLPIERPKSVTTQWIREHFE 476
           +SGI+L+  G + S+ +TV+F ++R +G ++        G+ I RP+ + T + +  F+
Sbjct: 365 YSGIILKAMG-IPSSMFTVIFAMARTVGWIAHWNEMHTDGMKIARPRQLYTGYDKRDFK 422


ref|ZP_00139206.2| COG0372: Citrate synthase [Pseudomonas aeruginosa UCBPP-PA14]
(404 aa)

Score: 105 bits (263), Expect: 2.25946e-21
Length: 358, Idn/Pos/Gap = 97/164/37 (27%/45%/10%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LLL GE+PT +Q E     +K    V  ++    +    +  HPM      +  L    
Sbjct:  64 YLLLNGELPTAAQKEQFVGTIKNHTMVHEQLKTFFNGFRRD-AHPMAVMCGVIGALS--- 119

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMG 250
               A+   +      ++    A  LIA++P +AA +Y+ +       P   +   ++  
Sbjct: 120 ----AFYHDSLDINNPKHREVSAHRLIAKMPTIAAMVYKYSKGEPMMYPRNDLNYAENF- 174

Query: 251 MRLARSLGFELNEFDEL----MRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGL 306
           + +  +   E      +    M    +LHADHE  N S   VRL GS+ ++P+   A+G+
Sbjct: 175 LHMMFNTPCETKPISPVLAKAMDRIFILHADHEQ-NASTSTVRLAGSSGANPFACIASGI 233

Query: 307 NGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRR 366
             L GP HG AN+ VLR L ++ + + N     E  ++       +   + GFGH V + 
Sbjct: 234 AALWGPAHGGANEAVLRMLDEIGD-VSNIDKFVEKAKD-----KNDPFKLMGFGHRVYKN 287

Query: 367 TDPRYTAQREF---ALKHLP-HDEMFQLVSKLYEVV---PRVLEEQGKVKNPWPNVDQHS 419
            DPR    ++     L+ L  +D   +L  KL E+    P  +E     +N +PNVD +S
Sbjct: 288 FDPRAKVMKQTCDEVLQELGINDPQLELAMKLEEIARHDPYFVE-----RNLYPNVDFYS 342

Query: 420 GILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP--IERPKSVTTQWIREHF 475
           GI+L+  G + ++ +TV+F ++R +G +S   W   L  P  I RP+ + T   +  F
Sbjct: 343 GIILKAIG-IPTSMFTVIFALARTVGWISH--WQEMLSGPYKIGRPRQLYTGHTQRDF 397


ref|ZP_00389828.1| COG0372: Citrate synthase [Streptococcus thermophilus LMD-9]
(374 aa)

Score: 105 bits (263), Expect: 2.33614e-21
Length: 327, Idn/Pos/Gap = 91/155/30 (27%/47%/9%)

Query: 127 EGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLR--LLDELPHERMHPMTQFSVAVS 184
           E +++LL  G +PT+ +++    +L++   +   V +  L+   PH  +HPM+     VS
Sbjct:  45 EEVIYLLWNGHLPTQMELKYFEAELRKNYDISDAVEQCILIQSRPH--LHPMSVLRSTVS 102

Query: 185 LLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIE 244
           LL   +  AE  +         E   + ++ L+A+LP +     R     GK +P +  +
Sbjct: 103 LLGVYNVDAEERSM--------EAVYQQSIELMAKLPTIITTFAR--LRTGK-MPLKPRK 151

Query: 245 KVDDMGMRLARSLGFELNEFD-ELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFA 303
            +      L    G E +E + E M   L+LHADHE  N S  A R+  S L+D Y    
Sbjct: 152 DLGFAANFLYMLNGAEPSEIEIEAMNKALILHADHEL-NASTFAARVCASTLTDIYSCIT 210

Query: 304 AGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAV 363
             +  L GPLHG AN+ V   L +++E        + ++     E L     I GFGH V
Sbjct: 211 TAIGALKGPLHGGANERVFDMLKEVRE--------SGDVNAYLQEKLDSKEKIMGFGHRV 262

Query: 364 LRRTDPRYTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILL 423
            ++ DPR    R+ A K     E  +  +K  E+   + +++G +    PNVD +S  + 
Sbjct: 263 YKKKDPREIFLRDMAKKLTEGTENEEFFNKSQEIEEFMRDKKGLI----PNVDFYSATVY 318

Query: 424 RYYGLVESNFYTVLFGVSRALGTLSSL 450
              G ++S+ +T++F +SR  G ++ +
Sbjct: 319 HTLG-IDSDIFTLIFAMSRVAGWIAHI 344


dbj|BAB06879.1| citrate synthase II [Bacillus halodurans C-125]
ref|NP_244026.1| citrate synthase II [Bacillus halodurans C-125]
pir||H84044 citrate synthase II citZ [imported] - Bacillus halodurans  (strain C-125)
(372 aa)

Score: 105 bits (263), Expect: 2.37545e-21
Length: 331, Idn/Pos/Gap = 95/149/36 (28%/45%/10%)

Query: 127 EGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLL 186
           E +++LL  G++P + +++ +  +L   A +P EV+  +   P +R+HPM     A+S L
Sbjct:  42 EEVIYLLWNGKLPNKVELKELADELANNAEIPQEVIEQMKAYPLDRVHPMGALRTAISSL 101

Query: 187 QHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKV 246
               + A+   + A K          AL L A++  V     R     GK   A + +  
Sbjct: 102 GLYDEEADLMDEAANK--------RKALKLQAQVSTVVTAFSR--IREGKEPVAPRTD-- 149

Query: 247 DDMGMRLARSLGFELN--EFDEL----MRLYLVLHADHEGGNVSAHAVRLVGSALSDPYL 300
               +  A +  + L   E DE+        LVLHADHE  N S    R+  + LSD Y 
Sbjct: 150 ----LSFAANFLYMLTGEEPDEIAVDAFNKALVLHADHE-LNASTFTARVCVATLSDVYS 204

Query: 301 SFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFG 360
              A +  L GPLHG AN++V+  L ++ +         EN+     + L     I GFG
Sbjct: 205 GITAAIGALKGPLHGGANEQVMAMLTEIGD--------VENVEPYIRKALDNKQKIMGFG 256

Query: 361 HAVLRRTDPRYTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSG 420
           H V +  DPR    RE + K           SK YE+  ++ E     K   PNVD +S 
Sbjct: 257 HRVYKNGDPRAKHLREMSKKLTS----ITGESKWYEMSVKIEEIVTNEKGLLPNVDFYSA 312

Query: 421 ILLRYYGLVESNFYTVLFGVSRALGTLSSLV 451
            +    G ++ + +T +F VSR  G L+ ++
Sbjct: 313 SVYHSLG-IKHDLFTPIFAVSRMSGWLAHIL 342


gb|AAF09126.1| citrate synthase [Lactococcus lactis subsp. lactis]
(441 aa)

Score: 105 bits (262), Expect: 2.87799e-21
Length: 341, Idn/Pos/Gap = 92/166/35 (26%/48%/10%)

Query: 127 EGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLR--LLDELPHERMHPMTQFSVAVS 184
           E + +LLL GE+P+  +++     L  +  +P   +R  +L     + M+ M++  +A++
Sbjct:  85 EEMTYLLLFGELPSAKELQEFQILLASKRTLPEFFVRETILTNPSSDVMNSMSRCLLALA 144

Query: 185 LLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGK------HV 238
                     +Y + A   +  E  LE +L LIA  P +A   Y+   H  K      H 
Sbjct: 145 ----------SYDKKASDISI-ENVLEQSLALIADFPLLAIYSYQAYIHYFKKESLYIHF 193

Query: 239 PAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDP 298
           P  ++   +++ +R+ R      +   +++ + L+LH +H GGN S     +V S+ +D 
Sbjct: 194 PDPELTTAENI-LRMLRPDCHYSDMEAKVLDIALILHMEHGGGNNSTFTTHVVTSSGTDT 252

Query: 299 YLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRE-----LCWETLREG 353
           Y + AA L+ L GP HG AN +  + L  +KE + +     E +++     L  E   + 
Sbjct: 253 YATIAAALSSLKGPKHGGANIKAAKMLENIKENISDYN-NDEEIKKYLHQILNKEVFDKQ 311

Query: 354 HVIPGFGHAVLRRTDPRYTAQREFA---LKHLPHDEMFQLVSKLYEVVPRVLEEQGKV-K 409
            +I G GHA+   +DPR+   + +     K    +E F+L  K+  + P+V+ E  K+ K
Sbjct: 312 GLIYGIGHAIYSVSDPRFEVFKSYVESLAKEKGLEEEFKLYEKVAFLAPKVISENRKIYK 371

Query: 410 NPWPNVDQHSGILLRYYGLVE--SNFYTVLFGVSRALGTLS 448
              PNVD +SG +   Y ++E     +T LF ++R +G L+
Sbjct: 372 TICPNVDFYSGFV---YKILEIPQELFTPLFAIARIVGWLA 409


ref|ZP_00185691.2| COG0372: Citrate synthase [Rubrobacter xylanophilus DSM 9941]
(445 aa)

Score: 105 bits (262), Expect: 3.10243e-21
Length: 360, Idn/Pos/Gap = 99/163/42 (27%/45%/11%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LL+ G +PTE ++     D+     V   +   +D   H+  HPM     +V  L    
Sbjct: 107 YLLIHGHLPTEEELSQWVYDITHHTYVHENIKSFMDGFRHD-AHPMGILLASVGALSTFY 165

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDD-- 248
             A        ++         A+ LIA++P +AA  YR++       P   +    +  
Sbjct: 166 PEASDIDDEEQRNM-------AAIRLIAKMPTIAAFAYRHSLGLPYVYPDNDLSYTGNFL 218

Query: 249 -MGMRLARSLGFELNEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLN 307
            M  ++A          ++ + +  +LHADHE  N S  AVR VGS  +DPY + AAG+ 
Sbjct: 219 SMLFKMAEPKYEPDPRLEKALDVLFILHADHEQ-NASTSAVRTVGSTRADPYTAVAAGVA 277

Query: 308 GLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREG-HVIPGFGHAVLRR 366
            L GPLHG AN  VL+    M +++G    + +N+ +   ET+++G   + GFGH V + 
Sbjct: 278 ALYGPLHGGANVAVLK----MLQRIG----SVKNIPDFL-ETVKQGKERLMGFGHRVYKN 328

Query: 367 TDPRYTAQREFALKHLPHDEMFQLVSK-------LYEVVPRVL-EEQGKVKNPWPNVDQH 418
            DPR    +         DE+ +   K         E+  R L +E    +  +PNVD +
Sbjct: 329 YDPRARIIKSHV------DEVLEATGKESPWLDIAVELEKRALDDEYFTSRKLYPNVDFY 382

Query: 419 SGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPKSVTTQWIREHF 475
           SG++    G + +  +TV+F + R  G ++   W   L  P   I RP+ + T    +H+
Sbjct: 383 SGLIYEALG-IPTEAFTVMFAIPRTSGWIAQ--WMEMLRDPELKIARPRQIYTGPRDQHY 439


ref|NP_420713.1| citrate synthase [Caulobacter crescentus CB15]
gb|AAK23881.1| citrate synthase [Caulobacter crescentus CB15]
pir||E87485 citrate synthase [imported] - Caulobacter crescentus
(426 aa)

Score: 105 bits (262), Expect: 3.12843e-21
Length: 353, Idn/Pos/Gap = 101/159/41 (28%/45%/11%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LLL GE+P   +      ++     +  +  R  +    +  HPM   + AV  L    
Sbjct:  87 YLLLNGELPKADEFAKFEHNITYHTMLHAQFDRFFEGFRRD-AHPMAVMTGAVGAL---- 141

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMG 250
             +  Y+         E  +  A  LIA++P +AAR Y+ T  G   V         +  
Sbjct: 142 --SAFYSDSINVDDAREREIS-AHRLIAKMPTIAARAYKYTV-GQPFVSPRNDLSYSENF 197

Query: 251 MRLARSLGFELNE----FDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGL 306
           +R+  ++  E  +        M    +LHADHE  N S   VRL GS+ + P+   AAG+
Sbjct: 198 LRMCFAVPAEDWKPNPVLTRAMDRIFILHADHEQ-NASTSTVRLAGSSGAHPFACIAAGI 256

Query: 307 NGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRR 366
             L GP HG ANQE     L+M E +G    + +N+++         + + GFGH V + 
Sbjct: 257 ACLWGPSHGGANQEA----LEMLETIG----SVDNIKDYVQGVKDRKYKLMGFGHRVYKN 308

Query: 367 TDPRYTAQREFA---LKHLPH--DEMFQLVSKLYEVV---PRVLEEQGKVKNPWPNVDQH 418
            DPR    ++ A   L  L H  D + Q+  +L +V    P  ++     +  +PN+D +
Sbjct: 309 FDPRAKVMQKTAHEVLAELGHNNDPLLQVAQELEKVALNDPYFVD-----RKLYPNIDFY 363

Query: 419 SGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPKSVTT 468
           SGI LR  G   +N +TVLF ++R +G +S   W      P   I RP+ + T
Sbjct: 364 SGITLRAMGF-PTNMFTVLFALARTVGWISQ--WKEMFEDPTRKIGRPRQLYT 413


ref|NP_250271.1| citrate synthase [Pseudomonas aeruginosa PAO1]
gb|AAG04969.1| citrate synthase [Pseudomonas aeruginosa PAO1]
pir||B83448 citrate synthase PA1580 [imported] - Pseudomonas aeruginosa  (strain PAO1)
sp|P14165|CISY_PSEAE Citrate synthase
(428 aa)

Score: 105 bits (262), Expect: 3.12843e-21
Length: 358, Idn/Pos/Gap = 97/164/37 (27%/45%/10%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LLL GE+PT +Q E     +K    V  ++    +    +  HPM      +  L    
Sbjct:  88 YLLLNGELPTAAQKEQFVGTIKNHTMVHEQLKTFFNGFRRD-AHPMAVMCGVIGALS--- 143

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMG 250
               A+   +      ++    A  LIA++P +AA +Y+ +       P   +   ++  
Sbjct: 144 ----AFYHDSLDINNPKHREVSAHRLIAKMPTIAAMVYKYSKGEPMMYPRNDLNYAENF- 198

Query: 251 MRLARSLGFELNEFDEL----MRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGL 306
           + +  +   E      +    M    +LHADHE  N S   VRL GS+ ++P+   A+G+
Sbjct: 199 LHMMFNTPCETKPISPVLAKAMDRIFILHADHEQ-NASTSTVRLAGSSGANPFACIASGI 257

Query: 307 NGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRR 366
             L GP HG AN+ VLR L ++ + + N     E  ++       +   + GFGH V + 
Sbjct: 258 AALWGPAHGGANEAVLRMLDEIGD-VSNIDKFVEKAKD-----KNDPFKLMGFGHRVYKN 311

Query: 367 TDPRYTAQREF---ALKHLP-HDEMFQLVSKLYEVV---PRVLEEQGKVKNPWPNVDQHS 419
            DPR    ++     L+ L  +D   +L  KL E+    P  +E     +N +PNVD +S
Sbjct: 312 FDPRAKVMKQTCDEVLQELGINDPQLELAMKLEEIARHDPYFVE-----RNLYPNVDFYS 366

Query: 420 GILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP--IERPKSVTTQWIREHF 475
           GI+L+  G + ++ +TV+F ++R +G +S   W   L  P  I RP+ + T   +  F
Sbjct: 367 GIILKAIG-IPTSMFTVIFALARTVGWISH--WQEMLSGPYKIGRPRQLYTGHTQRDF 421


gb|AAU24568.1| citrate synthase II [Bacillus licheniformis ATCC 14580]
ref|YP_092620.1| CitZ [Bacillus licheniformis ATCC 14580]
ref|YP_080206.1| citrate synthase II [Bacillus licheniformis ATCC 14580]
gb|AAU41927.1| CitZ [Bacillus licheniformis DSM 13]
(372 aa)

Score: 105 bits (261), Expect: 3.75878e-21
Length: 336, Idn/Pos/Gap = 98/152/46 (29%/45%/13%)

Query: 127 EGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLL 186
           E +++LL   ++P + ++  + + L   A +P EV+      P+ ++HPM     AVSLL
Sbjct:  42 EEVVYLLWHLKLPNKEELAELKKQLSENAGIPKEVIDHFKSYPNGKVHPMAALRTAVSLL 101

Query: 187 ---QHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKI 243
                E+   +A A               A+ L A++PA+ A   R     G     E I
Sbjct: 102 GLFDEEADQMDAEAN-----------YRKAVRLQAKMPALVAAFSR--IRKG----LEPI 144

Query: 244 EKVDDMGMRLARSLGFELNEFD------ELMRLYLVLHADHEGGNVSAHAVRLVGSALSD 297
           E   ++G   A +  + LN  +      E     L+LHADHE  N S    R+  + LSD
Sbjct: 145 EPNPELG--FAANFLYMLNGKEPSPVEVEAFDKALILHADHEL-NASTFTARVCVATLSD 201

Query: 298 PYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIP 357
            Y    A +  L GPLHG AN+ V++ L ++ E         EN+       L +   I 
Sbjct: 202 VYSGITAAIGALKGPLHGGANEAVMKMLSEIGE--------VENVDSYIHAKLEKKEKIM 253

Query: 358 GFGHAVLRRTDPRYTAQREFA--LKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNV 415
           GFGH V R+ DPR    +E +  L +L  +      SK YE+  R  E     K   PNV
Sbjct: 254 GFGHRVYRQGDPRAKHLKEMSRRLTNLTGE------SKWYEISERTEEIVTSQKKLPPNV 307

Query: 416 DQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLV 451
           D +S  +    G ++ + +T +F +SR  G L+ ++
Sbjct: 308 DFYSASVYHSLG-IDHDLFTPIFAISRVSGWLAHIL 342


ref|YP_199793.1| citrate synthase [Xanthomonas oryzae pv. oryzae KACC10331]
gb|AAW74408.1| citrate synthase [Xanthomonas oryzae pv. oryzae KACC10331]
(442 aa)

Score: 104 bits (260), Expect: 4.99172e-21
Length: 356, Idn/Pos/Gap = 98/162/30 (27%/45%/8%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LL+ GE+PT  + +    ++     +   +   L    H+  HPM   + +V+ L    
Sbjct: 102 YLLMNGELPTADEFKKFDHEVTHHTMMHESLKNFLGGFRHD-AHPMAMLAGSVASLS--- 157

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDM- 249
               A+          E   + A+ LIA++P +AA  YR +       P   +  VD   
Sbjct: 158 ----AFYHDTLDLNDPEQRRQAAIRLIAKVPTLAAAAYRYSIGWPIRYPRNNLNYVDRFL 213

Query: 250 -GMRLARSLGFELNEF-DELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLN 307
             M    S     N    + + L  +LHADHE  N S   VRLVGS   +PY S AAG+ 
Sbjct: 214 HMMFEVPSEPLATNPVVAKALDLLFILHADHEQ-NASTSTVRLVGSTGVNPYASVAAGIT 272

Query: 308 GLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHV--IPGFGHAVLR 365
            L GP HG AN+ VL+    M E++G    T +N+     +   +     + GFGH V +
Sbjct: 273 ALWGPAHGGANEAVLK----MLEEIG----TADNVESAVAKAKDKNSSFRLMGFGHRVYK 324

Query: 366 RTDPRYTAQREFALKHLP----HDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGI 421
             DPR    RE   K L     +D + ++  KL E   +  ++    +  +PNVD +SGI
Sbjct: 325 NFDPRAKIIREMTHKVLGELGVNDPLLEVALKLEEAALK--DDYFVQRKLYPNVDFYSGI 382

Query: 422 LLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRA-LGLPIERPKSVTTQWIREHFE 476
           + +    +    +TV+F ++R  G +S  +  +    + I RP+ + T + + +++
Sbjct: 383 IYKALN-IPVEMFTVMFAIARTAGWVSHWLEQQVDPEMKIGRPRQIYTGYDKRNYK 437


ref|ZP_00327320.1| COG0372: Citrate synthase [Trichodesmium erythraeum IMS101]
(383 aa)

Score: 104 bits (260), Expect: 5.24798e-21
Length: 398, Idn/Pos/Gap = 108/183/54 (27%/45%/13%)

Query:  80 GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEI 138
           G+  + A     S +D Q+GI  +RG +I E       AK S        L+W    G +
Sbjct:  11 GLEGVPATQSSVSYVDGQKGILEYRGINIEEL------AKKSSFLEAAYLLIW----GNL  60

Query: 139 PTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQ 198
           PT+ +++S  Q++     +   +  ++   P E  HPM     + + L         Y++
Sbjct:  61 PTQEELQSFEQEICLNRRIKYRIRDMMKCFP-ETGHPMDALQTSAAAL------GLFYSR 113

Query: 199 GAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLG 258
            A  +   EY  +  + L+A +P + A         G     + ++  DD+G   A +  
Sbjct: 114 RALDNP--EYIRKAVVRLLANIPTMVAAF--ELMRKGN----DPVKPRDDLGY--AANFL 163

Query: 259 FELNEFD------ELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGP 312
           + LNE +      ++  + L LHA+H   N S  +  +  S L+DPY   A+ +  LAGP
Sbjct: 164 YMLNEREPDPLAAKVFDICLTLHAEHTI-NASTFSAMVTASTLTDPYGVIASAVGTLAGP 222

Query: 313 LHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYT 372
           LHG AN++V+  L ++      +P         C+ET  +   I GFGH V +  DPR  
Sbjct: 223 LHGGANEDVISMLSEIGSVENVKPYLKR-----CFETKAK---IAGFGHRVYKVKDPRAI 274

Query: 373 AQREFAL---KHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLV 429
             +E A+   +    D+ +Q+  ++ +VV    EE+   K  +PNVD +SG++ R  G +
Sbjct: 275 ILQELAVDLFEKFGDDKYYQIALEMEKVV----EEKLGHKGIYPNVDFYSGLVYRKLG-I 329

Query: 430 ESNFYTVLFGVSRALGTLSSLVWDRALGLP-IERPKSV 466
            S+ +T +F ++R  G L+   W   L    I RP  +
Sbjct: 330 PSDLFTPVFAIARVAGWLAH--WKEQLAANRIFRPTQI 365


gb|AAA96341.1| citrate synthase II
(372 aa)

Score: 104 bits (260), Expect: 5.29195e-21
Length: 333, Idn/Pos/Gap = 96/151/40 (28%/45%/12%)

Query: 127 EGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLL 186
           E +++LL    +P + ++E + Q L + AAVP E++        E +HPM     A+SLL
Sbjct:  42 EEIIYLLWHLRLPNKKELEELKQQLAKEAAVPQEIIEHFKSYSLENVHPMAALRTAISLL 101

Query: 187 QHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKV 246
                 A+      P++ +       A+ L A++P + A   R     G     E +E  
Sbjct: 102 GLLDSEADTM---NPEANY-----RKAIRLQAKVPGLVAAFSR--IRKG----LEPVEPR 147

Query: 247 DDMGMRLARSLGFELNEFD------ELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYL 300
           +D G  +A +  + LN  +      E     L+LHADHE  N S    R+  + LSD Y 
Sbjct: 148 EDYG--IAENFLYTLNGEEPSPIEVEAFNKALILHADHE-LNASTFTARVCVATLSDIYS 204

Query: 301 SFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFG 360
              A +  L GPLHG AN+ V++ L ++ E         EN        L +   I GFG
Sbjct: 205 GITAAIGALKGPLHGGANEGVMKMLTEIGE--------VENAEPYIRAKLEKKEKIMGFG 256

Query: 361 HAVLRRTDPRYTAQREFA--LKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQH 418
           H V +  DPR    +E +  L +L  +      SK YE+  R+ +     K   PNVD +
Sbjct: 257 HRVYKHGDPRANDLKEMSKRLTNLTGE------SKWYEMSIRIEDIVTSEKKLPPNVDFY 310

Query: 419 SGILLRYYGLVESNFYTVLFGVSRALGTLSSLV 451
           S  +    G ++ + +T +F V R  G L+ ++
Sbjct: 311 SASVYHSLG-IDHDLFTPIFAVRRMSGWLAHIL 342


ref|ZP_00263259.1| COG0372: Citrate synthase [Pseudomonas fluorescens PfO-1]
(429 aa)

Score: 104 bits (260), Expect: 5.84924e-21
Length: 354, Idn/Pos/Gap = 94/164/38 (26%/46%/10%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LLL GE+PT  Q       +K    V  ++    +    +  HPM      V  L    
Sbjct:  88 YLLLNGELPTAEQKAQFVGTVKNHTMVHEQLKTFFNGFRRD-AHPMAVMCGVVGALS--- 143

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMG 250
               A+   +      ++    A+ L+A++P +AA +Y+ +       P   +   ++  
Sbjct: 144 ----AFYHDSLDINNPQHREISAIRLVAKMPTLAAMVYKYSMGQPMMYPRNDLSYAENF- 198

Query: 251 MRLARSLGFELNEFDEL----MRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGL 306
           + +  +   E+     +    M    +LHADHE  N S   VRL GS+ ++P+   AAG+
Sbjct: 199 LHMMFNTPCEIKPISPVLAKAMDRIFILHADHEQ-NASTSTVRLAGSSGANPFACIAAGI 257

Query: 307 NGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRR 366
             L GP HG AN+ V    L M +++G+     + + +   +   +   + GFGH V + 
Sbjct: 258 AALWGPAHGGANEAV----LTMLDEIGDVSNIDKFIAKA--KDKNDPFKLMGFGHRVYKN 311

Query: 367 TDPRYTAQREF---ALKHL--PHDEMFQLVSKLYEVV---PRVLEEQGKVKNPWPNVDQH 418
            DPR T  ++     LK L   +D   +L  +L E+    P  +E     ++ +PNVD +
Sbjct: 312 RDPRATVMKQTCDEVLKELGIQNDPQLELAMRLEEIALTDPYFIE-----RSLYPNVDFY 366

Query: 419 SGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP--IERPKSVTTQW 470
           SGI+L+  G + ++ +TV+F ++R +G +S   W   L  P  I RP+ + T +
Sbjct: 367 SGIILKAIG-IPTSMFTVIFALARTVGWISH--WKEMLSSPYKIGRPRQLYTGY 417


ref|ZP_00213111.1| COG0372: Citrate synthase [Burkholderia cepacia R18194]
(406 aa)

Score: 104 bits (259), Expect: 6.9115e-21
Length: 357, Idn/Pos/Gap = 99/165/51 (27%/46%/14%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LLL GE+P  +Q +     + +   V            HE+MH   +        +   
Sbjct:  65 YLLLKGELPNAAQKKEFVDTVTKHTMV------------HEQMHFFFR-----GFRRDAH 107

Query: 191 KMAEAYAQGAPKSTFWEYCLE---------DALTLIARLPAVAARIYRNTFHGGKHVPAE 241
            MA   A     S F+   L+          A+ +IA+LP + A  Y+ +       P  
Sbjct: 108 PMAILVAAVGALSAFYHDSLDINDPRHREVSAIRMIAKLPTLVAMAYKYSIGQPFVYPKN 167

Query: 242 KIEKVDDMGMRLARSLGFELNEFDELMRLY---LVLHADHEGGNVSAHAVRLVGSALSDP 298
            +    +    +  +   E    D L+R     L+LHADHE  N S   VRL GS+ ++P
Sbjct: 168 SLSYSANFMHMMFSNPCEEYKVNDVLVRALDRILILHADHEQ-NASTSTVRLAGSSGANP 226

Query: 299 YLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPG 358
           +   AAG+  L GP HG AN+      L M E++G+     E ++++  +    G  + G
Sbjct: 227 FACIAAGIACLWGPAHGGANEAA----LNMLEQIGSPDNIPEFIKQV--KDKNSGVKLMG 280

Query: 359 FGHAVLRRTDPRYTAQREFALKHLP----HDE-MFQLVSKLYEVVPRVLEEQGKV-KNPW 412
           FGH V +  DPR    RE   + L     HD+ +F+L  +L ++    LE++  V +  +
Sbjct: 281 FGHRVYKNYDPRAKLMRETCYEVLNELGLHDDPLFKLAMQLEKI---ALEDEYFVSRKLY 337

Query: 413 PNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPKSV 466
           PNVD +SGI+ R  G + ++ +T +F ++R +G ++   W+  +G P   I RP+ +
Sbjct: 338 PNVDFYSGIVQRALG-IPTSMFTCIFAMARTVGWIAQ--WNEMIGDPEQKIGRPRQL 391


ref|YP_148589.1| citrate synthaseII [Geobacillus kaustophilus HTA426]
dbj|BAD77021.1| citrate synthaseII [Geobacillus kaustophilus HTA426]
(372 aa)

Score: 104 bits (259), Expect: 7.14607e-21
Length: 332, Idn/Pos/Gap = 95/149/38 (28%/44%/11%)

Query: 127 EGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLL 186
           E +++LL   E+PT+ Q+E + + L   A +P E++      P +++HPM     AVSLL
Sbjct:  42 EEVVYLLWHRELPTKEQLEELKKQLAENAEIPNEIIEHFKLYPIDKVHPMAALRTAVSLL 101

Query: 187 QHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKV 246
               + A+   +        E     A+ L A++P +     R         P + +   
Sbjct: 102 GLYDEEADVMTK--------EANYRKAIRLQAKIPTIVTAFARVRKGLEPVAPRKDLSFA 153

Query: 247 DDMGMRLARSLGFELNEF-DELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAG 305
            +    L    G E ++   E     LVLHADHE  N S    R+  + LSD Y    A 
Sbjct: 154 ANFLYMLT---GKEPDDIATEAFNKALVLHADHE-LNASTFTARVCVATLSDIYSGITAA 209

Query: 306 LNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLR 365
           +  L GPLHG AN+ V++ L ++         T +N+       L     I GFGH V R
Sbjct: 210 IGALKGPLHGGANEAVMKMLTEIG--------TVDNVEPYIRRKLANKEKIMGFGHRVYR 261

Query: 366 RTDPRYTAQREFALKHLPHDEMFQLVSKL------YEVVPRVLEEQGKVKNPWPNVDQHS 419
           + DPR         KHL   +M + ++KL      YE+  ++ E     K   PNVD +S
Sbjct: 262 KGDPR--------AKHL--KKMSEKLTKLVGEPHWYEMSTKIEEIVTSEKALPPNVDFYS 311

Query: 420 GILLRYYGLVESNFYTVLFGVSRALGTLSSLV 451
             +    G ++ + +T +F VSR  G L+ ++
Sbjct: 312 ASVYHCLG-IDHDLFTPIFAVSRTSGWLAHIL 342


ref|ZP_00317127.1| COG0372: Citrate synthase [Microbulbifer degradans 2-40]
(454 aa)

Score: 103 bits (258), Expect: 8.03153e-21
Length: 362, Idn/Pos/Gap = 96/163/38 (26%/45%/10%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LLL GE+P+ ++ E     +     V   + R      H   HPM      V  L    
Sbjct: 106 YLLLHGELPSAAEYEEFKGIITHHTMVHESIARFFRGF-HYDSHPMAMMCGIVGALS--- 161

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMG 250
               A+   +   +  E+ L  A  LIA++P +AA  Y+++       P   +   ++  
Sbjct: 162 ----AFYHDSLDISNPEHRLISAHRLIAKMPTLAAMCYKHSQGQPFMYPDNNLGYAENF- 216

Query: 251 MRLARSLGFELNE------FDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAA 304
             L    G   ++          M    +LHADHE  N S   VRL GS+ ++P+   AA
Sbjct: 217 --LHMMFGTPCDDPKVNPVIARAMDRIFLLHADHE-QNASTSTVRLAGSSGANPFACIAA 273

Query: 305 GLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVL 364
           G+  L GP HG AN+ V    L M E++G+       + +   +   +   + GFGH V 
Sbjct: 274 GIATLWGPAHGGANEAV----LSMLEEIGDEKNIDAYVAKA--KDKNDPFRLMGFGHRVY 327

Query: 365 RRTDPRYTAQRE-----FALKHLPHDEMFQLVSKLYEVVPRVLEEQGKV-KNPWPNVDQH 418
           +  DPR    +E          L +D + ++  +L ++    LE++  + K  +PNVD +
Sbjct: 328 KNFDPRAKVMKETCDEVLTELGLENDPLLKIAKRLEQI---ALEDEYFIQKKLYPNVDFY 384

Query: 419 SGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRAL--GLPIERPKSVTTQWIREHFE 476
           SGI+++  G + ++ +TV+F   R +G ++   W   +  G  I RP+ + T  +   FE
Sbjct: 385 SGIIMKAIG-IPTDMFTVIFATGRTVGWIAH--WHEMISEGFKIGRPRQLYTGSVLREFE 441

Query: 477 KR 478
           +R
Sbjct: 442 ER 443


ref|NP_746311.1| citrate synthase [Pseudomonas putida KT2440]
gb|AAN69775.1| citrate synthase [Pseudomonas putida KT2440]
(429 aa)

Score: 103 bits (258), Expect: 8.87732e-21
Length: 352, Idn/Pos/Gap = 91/160/38 (25%/45%/10%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LLL GE+P   Q       +K    V  ++    +    +  HPM      V  L    
Sbjct:  88 YLLLNGELPNAEQKAQFVSTVKNHTMVHEQLKSFFNGFRRD-AHPMAVMCGVVGALS--- 143

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMG 250
               A+   +      ++    A+ L+A++P +AA +Y+ +       P   +   ++  
Sbjct: 144 ----AFYHDSLDINNPQHREISAVRLVAKMPTLAAMVYKYSMGQPMMYPRNDLSYAENF- 198

Query: 251 MRLARSLGFELNEFDEL----MRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGL 306
           + +  +   E+     +    M    +LHADHE  N S   VRL GS+ ++P+   AAG+
Sbjct: 199 LHMMFNTPCEIKPISPVLAKAMDRIFILHADHEQ-NASTSTVRLAGSSGANPFACIAAGI 257

Query: 307 NGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRR 366
             L GP HG AN+ V    L M +++G+     + + +   +   +   + GFGH V + 
Sbjct: 258 AALWGPAHGGANEAV----LTMLDEIGDVSNIDKFIAKA--KDKNDPFKLMGFGHRVYKN 311

Query: 367 TDPRYTAQ--------REFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQH 418
            DPR T          RE  +K+ P  E+   + ++    P  +E     ++ +PNVD +
Sbjct: 312 RDPRATVMKQTCDEVLRELGIKNDPQLELAMRLEEIALTDPYFIE-----RSLYPNVDFY 366

Query: 419 SGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP--IERPKSVTT 468
           SGI+L+  G + ++ +TV+F ++R +G +S   W   L  P  I RP+ + T
Sbjct: 367 SGIILKAIG-IPTSMFTVIFALARTVGWISH--WKEMLSSPYKIGRPRQLYT 415


ref|YP_192391.1| Citrate synthase [Gluconobacter oxydans 621H]
gb|AAW61735.1| Citrate synthase [Gluconobacter oxydans 621H]
(431 aa)

Score: 103 bits (258), Expect: 9.9773e-21
Length: 425, Idn/Pos/Gap = 119/183/58 (28%/43%/13%)

Query:  65 GEEVLDACTVNQAYG------GMRSLKAMVYETSLLDPQEGIRFRGFSIPECQRLLPRAK 118
           G +V+D   ++Q  G      G+ S        S +D  +G+            LL R  
Sbjct:  26 GPDVVDMRALSQKTGVFSFDPGLGSTATCTSAISYIDGDKGV------------LLHRGY  73

Query: 119 PSGEQPLPEGLL---WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHP 175
           P  +  L        +LLL GE+PT +Q ++   D+     +  ++    +    +  HP
Sbjct:  74 PIEDLALNASFTETAYLLLYGELPTAAQYQAFRTDMNTHRLLNEQIRNFFNGFRRD-AHP 132

Query: 176 MTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGG 235
           M      V  L   +   +      PK+         A  LIA++P +AA  Y+ +    
Sbjct: 133 MAILCGTVGALS--AFYHDGLDISEPKARDLS-----ARRLIAKVPTIAAWAYKYSIGEP 185

Query: 236 KHVPAEKIEKVDD-MGMRLARSLG-FELNE-FDELMRLYLVLHADHEGGNVSAHAVRLVG 292
              P E++   ++ + M  AR    + +N      M   L+LHADHE  N S   VRLVG
Sbjct: 186 FIYPDEEMSFSENFLHMLFARPGNHYRVNPVLARAMDRILLLHADHEQ-NASTTTVRLVG 244

Query: 293 SALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLRE 352
           S  ++PY   AAG+  L GP HG AN+      L M E +G R      L E+  +    
Sbjct: 245 STGANPYACIAAGIAALWGPAHGGANEAA----LGMLETIGTRDGIPAFLNEV--KNRNS 298

Query: 353 GHVIPGFGHAVLRRTDPR--------YTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEE 404
           G  + GFGH V +  DPR        +    E  LK    D +  L  +L  V     ++
Sbjct: 299 GVRLMGFGHRVYKNFDPRAKILQATCHEVIEELGLK---RDPLLDLAMELERVATE--DD 353

Query: 405 QGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IE 461
               +  +PNVD +SG++L+  G+ +S F TVLF V+R +G +S   W   +  P   I 
Sbjct: 354 YFVSRRLYPNVDFYSGLILKALGIPKSMF-TVLFAVARTVGWVSQ--WKEMIEEPSVRIS 410

Query: 462 RPKSV 466
           RP+ +
Sbjct: 411 RPRQL 415


ref|ZP_00339681.1| COG0372: Citrate synthase [Silicibacter sp. TM1040]
(431 aa)

Score: 102 bits (255), Expect: 1.75963e-20
Length: 354, Idn/Pos/Gap = 102/162/45 (28%/45%/12%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LLL GE+PT +Q+E     + R   V  ++         +  HPM       +L+    
Sbjct:  90 YLLLYGELPTATQLEDFETRVTRHTMVHEQMHNFFRGFRRD-AHPMA------TLVGVVG 142

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMG 250
            M+  Y      S  W+  +  A+ LIA+LP +AA  Y+ +       P   ++   +  
Sbjct: 143 AMSAFYHDSTDISDPWQREVA-AIRLIAKLPTIAAMAYKYSIGQPFVYPRNDLDYAANF- 200

Query: 251 MRLARSLGFELNEFDEL----MRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGL 306
           + +  S+  E    D +    M     LHADHE  N S   VRL  S+ ++P+   AAG+
Sbjct: 201 LHMCFSVPAENYTVDPILSRAMDRIFTLHADHEQ-NASTSTVRLASSSGANPFACIAAGI 259

Query: 307 NGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRR 366
             L GP HG ANQ      L+M +++G+     E +     +   +   + GFGH V + 
Sbjct: 260 ACLWGPAHGGANQAC----LEMLKEIGSVDRIPEFIARA--KDKNDPFRLMGFGHRVYKN 313

Query: 367 TDPRYTAQREFALKHLPHDEMFQLV----SKLYEVVPRVLEEQGKVKNPW-------PNV 415
           TDPR    ++ A      DE+ +L+    + L +V   +  EQ  + +P+       PNV
Sbjct: 314 TDPRAKVLKQSA------DEVLELLGVEDNPLLQVAKEL--EQTALNDPYFIEKKLFPNV 365

Query: 416 DQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPKSV 466
           D +SGI+L   G   S F T +F +SR +G +S   W   +G P   I RP+ +
Sbjct: 366 DFYSGIILEAMGFPTSMF-TPIFALSRTVGWISQ--WKEMIGDPQNKIGRPRQL 416


emb|CAD86285.1| Citrate synthase [Nitrosomonas europaea ATCC 19718]
ref|NP_842368.1| Citrate synthase [Nitrosomonas europaea ATCC 19718]
(427 aa)

Score: 102 bits (255), Expect: 1.89685e-20
Length: 348, Idn/Pos/Gap = 93/160/33 (26%/45%/9%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LLL GE+PT  Q      ++K    +  ++++ L     +  HPM      V  L    
Sbjct:  91 YLLLNGELPTPDQKAKFVDNIKNHTMLHEQLIKFLSGFRRD-AHPMAVMVGVVGALS--- 146

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMG 250
               A+   A   +  ++  + A  LIA+LP + A  Y+         P   +   ++  
Sbjct: 147 ----AFYHDAMDVSDAQHREQSAFRLIAKLPTITAIAYKYNIGQPFIYPHNDLGFTENFL 202

Query: 251 MRLARSLGFELNEFDELMRLY---LVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLN 307
             +  +   +      ++R     L+LHADHE  N S   VRL GS+ ++P+   +AG+ 
Sbjct: 203 HMMFATPAEQYTPNPVIVRALDRILILHADHEQ-NASTSTVRLAGSSGANPFACISAGIT 261

Query: 308 GLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRT 367
            L GP HG AN+      L M E++G+     E +     +   +   + GFGH V +  
Sbjct: 262 CLWGPAHGGANEAC----LNMLEQIGDVSRINEYIARA--KDKNDPFRLMGFGHRVYKNF 315

Query: 368 DPRYTAQREFALK-----HLPHDEMFQLVSKLYEVVPRVLEEQGKV-KNPWPNVDQHSGI 421
           DPR T  RE   +      L +D +F+L  +L ++    LE+   + K  +PNVD +SGI
Sbjct: 316 DPRATLMRETCHEVLDELGLHNDRLFKLALELEKI---ALEDDYFITKKLYPNVDFYSGI 372

Query: 422 LLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPKSV 466
           + R  G + ++ +T +F  +R +G ++   W+  +  P   I RP+ +
Sbjct: 373 VQRALG-IPTSMFTAIFATARTVGWVAQ--WNEMISDPEQKIGRPRQL 417


ref|ZP_00124271.1| COG0372: Citrate synthase [Pseudomonas syringae pv. syringae B728a]
(429 aa)

Score: 102 bits (255), Expect: 2.07919e-20
Length: 363, Idn/Pos/Gap = 96/159/60 (26%/43%/16%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LLL GE+PT  Q       +K    V  ++    +    +  HPM      V  L    
Sbjct:  88 YLLLNGELPTAEQKAQFVAVVKNHTMVHEQLKTFFNGFRRD-AHPMAVMCGVVGALS--- 143

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMG 250
               A+   +      ++    A+ L+A++P +AA +Y+ +       P   +   ++  
Sbjct: 144 ----AFYHDSLDINNPQHREISAVRLVAKMPTLAAMVYKYSMGQPMMYPRNDLSYAENF- 198

Query: 251 MRLARSLGFELNEFDEL----MRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGL 306
           + +  +   E+     +    M    +LHADHE  N S   VR+ GS+ ++P+   AAG+
Sbjct: 199 LHMMFNTPCEIKPISPVLAKAMDKIFILHADHEQ-NASTSTVRMAGSSGANPFACIAAGI 257

Query: 307 NGLAGPLHGLANQEVLRWLLQM-----------KEKLGNRPMTTENLRELCWETLREGHV 355
             L GP HG AN+ VL  L ++           K K  N P                   
Sbjct: 258 AALWGPAHGGANEAVLTMLDEIGDVSNIDTFIAKAKDKNDPFK----------------- 300

Query: 356 IPGFGHAVLRRTDPRYTAQREF---ALKHL--PHDEMFQLVSKLYEVV---PRVLEEQGK 407
           + GFGH V +  DPR T  ++     LK L   +D   +L  +L E+    P  +E    
Sbjct: 301 LMGFGHRVYKNRDPRATVMKQTCDEVLKELGITNDPQLELAMRLEEIALTDPYFIE---- 356

Query: 408 VKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP--IERPKS 465
            ++ +PNVD +SGI+L+  G + ++ +TV+F ++R +G +S   W   L  P  I RP+ 
Sbjct: 357 -RSLYPNVDFYSGIILKAIG-IPTSMFTVIFALARTVGWISH--WKEMLSSPYKIGRPRQ 412

Query: 466 VTT 468
           + T
Sbjct: 413 LYT 415


ref|NP_792015.1| citrate synthase I [Pseudomonas syringae pv. tomato str. DC3000]
gb|AAO55710.1| citrate synthase I [Pseudomonas syringae pv. tomato str. DC3000]
(429 aa)

Score: 102 bits (255), Expect: 2.13189e-20
Length: 363, Idn/Pos/Gap = 96/159/60 (26%/43%/16%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LLL GE+PT  Q       +K    V  ++    +    +  HPM      V  L    
Sbjct:  88 YLLLNGELPTAEQKAQFVAVVKNHTMVHEQLKTFFNGFRRD-AHPMAVMCGVVGALS--- 143

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMG 250
               A+   +      ++    A+ L+A++P +AA +Y+ +       P   +   ++  
Sbjct: 144 ----AFYHDSLDINNPQHREISAVRLVAKMPTLAAMVYKYSMGQPMMYPRNDLSYAENF- 198

Query: 251 MRLARSLGFELNEFDEL----MRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGL 306
           + +  +   E+     +    M    +LHADHE  N S   VR+ GS+ ++P+   AAG+
Sbjct: 199 LHMMFNTPCEIKPISPVLAKAMDKIFILHADHEQ-NASTSTVRMAGSSGANPFACIAAGI 257

Query: 307 NGLAGPLHGLANQEVLRWLLQM-----------KEKLGNRPMTTENLRELCWETLREGHV 355
             L GP HG AN+ VL  L ++           K K  N P                   
Sbjct: 258 AALWGPAHGGANEAVLTMLDEIGDVSNIDTFIAKAKDKNDPFK----------------- 300

Query: 356 IPGFGHAVLRRTDPRYTAQREF---ALKHL--PHDEMFQLVSKLYEVV---PRVLEEQGK 407
           + GFGH V +  DPR T  ++     LK L   +D   +L  +L E+    P  +E    
Sbjct: 301 LMGFGHRVYKNRDPRATVMKQTCDEVLKELGIKNDPQLELAMRLEEIALTDPYFIE---- 356

Query: 408 VKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP--IERPKS 465
            ++ +PNVD +SGI+L+  G + ++ +TV+F ++R +G +S   W   L  P  I RP+ 
Sbjct: 357 -RSLYPNVDFYSGIILKAIG-IPTSMFTVIFALARTVGWISH--WKEMLSSPYKIGRPRQ 412

Query: 466 VTT 468
           + T
Sbjct: 413 LYT 415


emb|CAA10007.1| citrate synthase [Nostoc sp. PCC 7120]
(378 aa)

Score: 102 bits (254), Expect: 2.3174e-20
Length: 381, Idn/Pos/Gap = 98/177/55 (25%/46%/14%)

Query:  80 GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEI 138
           G+  + A     S +D Q+GI  +RG  I +            +Q       +LL+ GE+
Sbjct:   9 GLEGIPAAQSSISYVDGQKGILEYRGIRIEDL----------AQQSTFLETAYLLIWGEL  58

Query: 139 PTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQ 198
           PT+ +++   ++++    +   +  ++   P E  HPM     + + L       + + +
Sbjct:  59 PTKEELQVFEEEVRLHRRIKYRIRDMMKCFP-ESGHPMDALQASAAALGLFYSRRDLHNR 117

Query: 199 GAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLG 258
                    Y  +  + LIA +P + A         G     + ++  DD+    + +  
Sbjct: 118 C--------YIRDAVVRLIATIPTMVAAF--QLMRKGN----DPVKPRDDLDY--SANFL 161

Query: 259 FELNEFD------ELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGP 312
           + LNE +      ++  + L+LH +H   N S  + R+  S L+DPY   A+ +  L GP
Sbjct: 162 YMLNEKEPDALAAKIFDICLILHVEHTM-NASTFSARVTASTLTDPYAVVASAVGTLGGP 220

Query: 313 LHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYT 372
           LHG AN+EV    +QM E++G    + EN+R    E L+    + GFGH V +  DPR T
Sbjct: 221 LHGGANEEV----IQMLEEIG----SVENVRSYVEERLQRKDKLMGFGHRVYKVKDPRAT 272

Query: 373 AQREFALKHLPHDEMFQL--VSKLYEV---VPRVLEEQGKVKNPWPNVDQHSGILLRYYG 427
             +  A      +++F      K Y++   + RV+EE+   K  +PNVD +SG++ R  G
Sbjct: 273 ILQGLA------EQLFAKFGADKYYDIAQEMERVVEEKLGHKGIYPNVDFYSGLVYRKMG 326

Query: 428 LVESNFYTVLFGVSRALGTLS 448
            + ++ +T +F ++R  G L+
Sbjct: 327 -IPTDLFTPIFAIARVAGWLA 346


ref|ZP_00371237.1| citrate synthase I [Campylobacter upsaliensis RM3195]
gb|EAL53229.1| citrate synthase I [Campylobacter upsaliensis RM3195]
(421 aa)

Score: 102 bits (254), Expect: 2.3174e-20
Length: 420, Idn/Pos/Gap = 108/193/47 (25%/45%/11%)

Query:  64 FGEEVLDACTVNQAYG------GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQRLLPR 116
            G  V+D  +  +  G      G+ S      + + +D ++GI + RG+SI         
Sbjct:  25 LGPSVVDMSSFYKQTGMFCYDEGLTSTATCKSQITYIDGEKGILKHRGYSIEWL------  78

Query: 117 AKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPM 176
                E  L   ++ LLL  E+P+  ++ES   +LK+R+ +   + +L D  P +  HPM
Sbjct:  79 ----AENKLFLDVVHLLLYKELPSAERLESFRYELKKRSFIHEGMHKLFDAFP-DNAHPM 133

Query: 177 TQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGK 236
                AVS       ++  Y      +   EY +E A  ++A++P + A  YR  +  G 
Sbjct: 134 AVLQGAVS------SLSAFYPDHLNMNVKEEY-MEMAARIVAKIPTIVATAYR--YKNGF 184

Query: 237 HVPAEKIEK-VDDMGMRLARSLGFELNEFDEL----MRLYLVLHADHEGGNVSAHAVRLV 291
            +    +++   +  + + R+  ++  +   +    +    +LHADHE  N S   VR V
Sbjct: 185 PMAYPNLDRGFTENFLYMLRTYPYDHVKLRPIEIKALDTVFMLHADHEQ-NASTSTVRAV 243

Query: 292 GSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLR 351
           GS  + PY   +AG+  L G  HG AN+ V+R    M E +G      E +++   +   
Sbjct: 244 GSTHAHPYACISAGIGALWGHAHGGANEGVIR----MLEMIGTPDRVDEFIKKA--KDKN 297

Query: 352 EGHVIPGFGHAVLRRTDPR---YTAQREFALKHLPHD-EMFQLVSKLYEVVPRVLEEQGK 407
           +   + GFGH V +  DPR       R+  +  L  D  + ++ +K+ E+   + ++   
Sbjct: 298 DPFRLMGFGHRVYKNFDPRAKVLKKLRDQLIDELDIDTNLIKVATKIEEIA--LQDDYFV 355

Query: 408 VKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRAL-GLPIERPKSV 466
            +N +PNVD HSG++L+  G+    F T LF + R  G ++  +  +    L I RP+ +
Sbjct: 356 QRNLYPNVDFHSGLILKALGIPNEMFAT-LFVIGRTPGWVAQWIEQKEQESLKIVRPRQL 414


pir||I39506 citrate (si)-synthase (EC 4.1.3.7) - Acinetobacter anitratus
sp|P20902|CISY_ACIAN Citrate synthase
gb|AAA21893.1| citrate synthase precursor
(424 aa)

Score: 102 bits (254), Expect: 2.3564e-20
Length: 381, Idn/Pos/Gap = 102/165/80 (26%/43%/20%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LLL GE+PT  Q       ++    V  +V R  +    +  HPM      V  L    
Sbjct:  90 YLLLNGELPTAEQKVEFDAKVRAHTMVHDQVSRFFNGFRRD-AHPMAIMVGVVGAL---- 144

Query: 191 KMAEAYAQGAPKSTFWEYCLE---------DALTLIARLPAVAARIYR------------ 229
                       S F+   L+          A+ LIA++P +AA  Y+            
Sbjct: 145 ------------SAFYHNNLDIEDINHREITAIRLIAKIPTLAAWSYKYTVGQPFIYPRN 192

Query: 230 ------NTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVLHADHEGGNV 283
                 N  H     PA++  KV+ +   LAR+           M     LHADHE  N 
Sbjct: 193 DLNYAENFLHMMFATPADRDYKVNPV---LARA-----------MDRIFTLHADHEQ-NA 237

Query: 284 SAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLR 343
           S   VRL GS  ++PY   +AG++ L GP HG AN+ VL+    M +++G    + EN+ 
Sbjct: 238 STSTVRLAGSTGANPYACISAGISALWGPAHGGANEAVLK----MLDEIG----SVENVA 289

Query: 344 ELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLP----HDEMFQLVSKLYEVV- 398
           E   +  R+   + GFGH V +  DPR    ++   + L     +D    L  +L  +  
Sbjct: 290 EFMEKVKRKEVKLMGFGHRVYKNFDPRAKVMKQTCDEVLEALGINDPQLALAMELERIAL 349

Query: 399 --PRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRAL 456
             P  +E     +  +PNVD +SGI+L+  G + +  +TV+F ++R +G +S  +   + 
Sbjct: 350 NDPYFVE-----RKLYPNVDFYSGIILKAIG-IPTEMFTVIFALARTVGWISHWLEMHSG 403

Query: 457 GLPIERPKSVTTQWIREHFEK 477
              I RP+ + T  ++   ++
Sbjct: 404 PYKIGRPRQLYTGEVQRDIKR 424


emb|CAB44667.1| citrate synthase [Nostoc sp. PCC 7120]
dbj|BAB77746.1| citrate synthase [Nostoc sp. PCC 7120]
ref|NP_484266.1| citrate synthase [Nostoc sp. PCC 7120]
pir||AF1834 citrate synthase [imported] - Nostoc sp. (strain PCC 7120)
(378 aa)

Score: 102 bits (254), Expect: 2.43637e-20
Length: 381, Idn/Pos/Gap = 98/176/55 (25%/46%/14%)

Query:  80 GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEI 138
           G+  + A     S +D Q+GI  +RG  I +            +Q       +LL+ GE+
Sbjct:   9 GLEGIPAAQSSISYVDGQKGILEYRGIRIEDL----------AQQSTFLETAYLLIWGEL  58

Query: 139 PTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQ 198
           PT+ +++   ++++    +   +  ++   P E  HPM     + + L       + +  
Sbjct:  59 PTKEELQVFEEEVRLHRRIKYRIRDMMKCFP-ESGHPMDALQASAAALGLFYSRRDLHNP 117

Query: 199 GAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLG 258
                    Y  +  + LIA +P + A         G     + ++  DD+    + +  
Sbjct: 118 A--------YIRDAVVRLIATIPTMVAAF--QLMRKGN----DPVKPRDDLDY--SANFL 161

Query: 259 FELNEFD------ELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGP 312
           + LNE +      ++  + L+LH +H   N S  + R+  S L+DPY   A+ +  L GP
Sbjct: 162 YMLNEKEPDALAAKIFDICLILHVEHTM-NASTFSARVTASTLTDPYAVVASAVGTLGGP 220

Query: 313 LHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYT 372
           LHG AN+EV    +QM E++G    + EN+R    E L+    + GFGH V +  DPR T
Sbjct: 221 LHGGANEEV----IQMLEEIG----SVENVRSYVEERLQRKDKLMGFGHRVYKVKDPRAT 272

Query: 373 AQREFALKHLPHDEMFQL--VSKLYEV---VPRVLEEQGKVKNPWPNVDQHSGILLRYYG 427
             +  A      +++F      K Y++   + RV+EE+   K  +PNVD +SG++ R  G
Sbjct: 273 ILQGLA------EQLFAKFGADKYYDIAQEMERVVEEKLGHKGIYPNVDFYSGLVYRKMG 326

Query: 428 LVESNFYTVLFGVSRALGTLS 448
            + ++ +T +F ++R  G L+
Sbjct: 327 -IPTDLFTPIFAIARVAGWLA 346


ref|ZP_00219852.1| COG0372: Citrate synthase [Burkholderia cepacia R1808]
(413 aa)

Score: 102 bits (253), Expect: 3.26265e-20
Length: 357, Idn/Pos/Gap = 98/164/51 (27%/45%/14%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LLL GE+P  +Q +     + +   V            HE+MH   +        +   
Sbjct:  72 YLLLKGELPNAAQKKEFVDTVTKHTMV------------HEQMHFFFR-----GFRRDAH 114

Query: 191 KMAEAYAQGAPKSTFWEYCLE---------DALTLIARLPAVAARIYRNTFHGGKHVPAE 241
            MA   A     S F+   L+          A+ +IA+LP + A  Y+ +       P  
Sbjct: 115 PMAILVAAVGALSAFYHDSLDINDPRHREVSAIRMIAKLPTLVAMAYKYSIGQPFVYPKN 174

Query: 242 KIEKVDDMGMRLARSLGFELNEFDELMRLY---LVLHADHEGGNVSAHAVRLVGSALSDP 298
            +    +    +  +   E    D L+R     L+LHADHE  N S   VRL GS+ ++P
Sbjct: 175 SLSYSANFMHMMFSNPCEEYKVNDVLVRALDRILILHADHEQ-NASTSTVRLAGSSGANP 233

Query: 299 YLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPG 358
           +   AAG+  L GP HG AN+      L M E++G+     E ++++  +    G  + G
Sbjct: 234 FACIAAGIACLWGPAHGGANEAA----LNMLEQIGSPDNIPEFIKQV--KDKNSGVKLMG 287

Query: 359 FGHAVLRRTDPRYTAQREFALKHLP----HDE-MFQLVSKLYEVVPRVLEEQGKV-KNPW 412
           FGH V +  DPR    RE   + L     HD+ +F+L  +L ++    LE++  V +  +
Sbjct: 288 FGHRVYKNYDPRAKLMRETCYEVLNELGLHDDPLFKLAMQLEKI---ALEDEYFVSRKLY 344

Query: 413 PNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPKSV 466
           PNVD +SGI+ R  G + ++ +T +F ++R +G ++   W+  +  P   I RP+ +
Sbjct: 345 PNVDFYSGIVQRALG-IPTSMFTCIFAMARTVGWIAQ--WNEMIADPEQKIGRPRQL 398


ref|YP_111721.1| citrate synthase [Burkholderia pseudomallei K96243]
emb|CAH39189.1| citrate synthase [Burkholderia pseudomallei K96243]
ref|YP_106303.1| citrate synthase I [Burkholderia mallei ATCC 23344]
gb|AAU45682.1| citrate synthase I [Burkholderia mallei ATCC 23344]
(433 aa)

Score: 101 bits (252), Expect: 4.0194e-20
Length: 361, Idn/Pos/Gap = 104/166/59 (28%/45%/16%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LLL GE+P  +Q +     + +   V  E ++          HPM     AV  L    
Sbjct:  92 YLLLKGELPNAAQKKEFVATVTKHTMVH-EQMQFFFRGFRRDAHPMAILVAAVGAL---- 146

Query: 191 KMAEAYAQGAPKSTFWEYCLE---------DALTLIARLPAVAARIYRNTFHGGKHVPAE 241
                       S F+   L+          A+ +IA+LP + A  Y+ +       P  
Sbjct: 147 ------------SAFYHDSLDINDPRHREVSAIRMIAKLPTLVAMAYKYSIGQPFVYPRN 194

Query: 242 KIE-KVDDMGMRLARSLG-FELNEFDELMRLY---LVLHADHEGGNVSAHAVRLVGSALS 296
            +    + M M  A     +++N  D L+R     L+LHADHE  N S   VRL GS+ +
Sbjct: 195 DLSYSANFMRMMFANPCEEYQVN--DVLVRALDRILILHADHEQ-NASTSTVRLAGSSGA 251

Query: 297 DPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWET--LREGH 354
           +P+   AAG+  L GP HG AN+      L M E++G    T EN+ E   +      G 
Sbjct: 252 NPFACIAAGIACLWGPAHGGANEAA----LNMLEQIG----TPENIPEFIKQVKDKNSGV 303

Query: 355 VIPGFGHAVLRRTDPRYTAQREFALKHLP----HDE-MFQLVSKLYEVVPRVLEEQGKV- 408
            + GFGH V +  DPR    RE   + L     HD+ +F+L  +L ++    LE++  V 
Sbjct: 304 KLMGFGHRVYKNYDPRAKLMRETCYEVLNELGLHDDPLFKLAMQLEKI---ALEDEYFVS 360

Query: 409 KNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPKS 465
           +  +PNVD +SGI+ R  G + ++ +T +F ++R +G ++   W+  +  P   I RP+ 
Sbjct: 361 RKLYPNVDFYSGIVQRALG-IPTSMFTCIFAMARTVGWIAQ--WNEMIADPEQKIGRPRQ 417

Query: 466 V 466
           +
Sbjct: 418 L 418


ref|NP_228102.1| citrate synthase [Thermotoga maritima MSB8]
gb|AAD35378.1| citrate synthase [Thermotoga maritima MSB8]
pir||B72394 citrate synthase - Thermotoga maritima (strain MSB8)
(367 aa)

Score: 101 bits (251), Expect: 5.16263e-20
Length: 339, Idn/Pos/Gap = 94/153/40 (27%/45%/11%)

Query: 112 RLLPRAKPS---GEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDEL 168
           RL  R  P     E+   E   + L  G++PT+S++E   + +     +P E L +L  L
Sbjct:  25 RLYYRGIPVEELAEKSTFEETAYFLWYGKLPTKSELEEFKRKMADYRELPAEALGILYHL  84

Query: 169 PHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIY 228
           P + +H +    + +S+  H S                E   E A+ + +  P + A  Y
Sbjct:  85 P-KNLHYIDVLKIFLSI--HGSMDGND-----------EDLREKAIRVASVFPTILAYYY 130

Query: 229 RNTFHGGKHV--PAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVLHADHEGGNVSAH 286
           R  +  GK +  P + +  V++    +    G E NE   L+    +L  + +  N S  
Sbjct: 131 R--YSKGKELIRPRKDLSHVENFYYMM---FG-ERNEKIRLLESAFILLMEQDI-NASTF 183

Query: 287 AVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELC 346
           A  ++ S LSD Y      L  L GPLHG A+++V      M E++G    + + + E  
Sbjct: 184 AALVIASTLSDLYSCIVGALGALKGPLHGGASEKVP----PMLEEIG----SEDRVEEFV 235

Query: 347 WETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQG 406
            + L+E   I GFGH V +  DPR    +    +H P  ++F++ SKL E +        
Sbjct: 236 QKCLKEKRKIMGFGHRVYKTYDPRAVFLKRVLQEHFPDSKLFRIASKLEEYIV-----SN 290

Query: 407 KVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALG 445
           K+KN +PNVD +S +L    G    N +T LF  +R +G
Sbjct: 291 KIKNIYPNVDLYSSVLFEELGF-PRNMFTALFATARVVG 328


ref|ZP_00281961.1| COG0372: Citrate synthase [Burkholderia fungorum LB400]
(432 aa)

Score: 101 bits (251), Expect: 5.42766e-20
Length: 350, Idn/Pos/Gap = 99/160/37 (28%/45%/10%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LLL GE+P   Q E   + + +   V  ++         +  HPM     AV  L    
Sbjct:  91 YLLLKGELPNAQQKEEFVKTVTQHTMVHDQMHFFFRGFRRD-AHPMAILVAAVGALS--- 146

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMG 250
               A+   +   +  E+    A+ +IA+LP + A  Y+ T       P   +    +  
Sbjct: 147 ----AFYHDSLDISNPEHREISAIRMIAKLPTLVAMAYKYTVGQPFVYPKNDLSYSANFM 202

Query: 251 MRLARSLGFELNEFDELMRLY---LVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLN 307
             +  +   E    D L+R     L+LHADHE  N S   VRL GS+ ++P+   AAG+ 
Sbjct: 203 RMMFANPAEEYKVNDVLVRALDRILILHADHEQ-NASTSTVRLAGSSGANPFACIAAGIA 261

Query: 308 GLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWET--LREGHVIPGFGHAVLR 365
            L GP HG AN+      L M E++G    + +N+ E   +      G  + GFGH V +
Sbjct: 262 CLWGPAHGGANEAA----LNMLEEIG----SVDNIPEFIAQVKDKNSGVKLMGFGHRVYK 313

Query: 366 RTDPRYTAQREFALKHLP----HDE-MFQLVSKLYEVVPRVLEEQGKV-KNPWPNVDQHS 419
             DPR    RE   + L     HD+ +F+L   L ++    LE+   V +  +PNVD +S
Sbjct: 314 NYDPRAKLMRETCHEVLEELGLHDDPLFKLAMALEKI---ALEDDYFVSRKLYPNVDFYS 370

Query: 420 GILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPKSV 466
           GI+ R  G + +  +T +F ++R +G ++   W+  +  P   I RP+ +
Sbjct: 371 GIVQRALG-IPTAMFTCIFAMARTVGWIAQ--WNEMIADPEQKIGRPRQL 417


ref|ZP_00106596.1| COG0372: Citrate synthase [Nostoc punctiforme PCC 73102]
(378 aa)

Score: 101 bits (251), Expect: 6.36007e-20
Length: 396, Idn/Pos/Gap = 103/173/50 (26%/43%/12%)

Query:  80 GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEI 138
           G+  + A     S +D Q+GI  +RG  I E            E+       +LL+ GE+
Sbjct:   9 GLEGIPAAQSSISYVDGQKGILEYRGIRIEEL----------AEKSTFLETAYLLIWGEL  58

Query: 139 PTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQ 198
           P++ ++E    +++    +   +  ++   P E  HPM     + + L     + + +  
Sbjct:  59 PSKEELEGFEHEVRYHRRIKYRIRDMMKCFP-ESGHPMDALQASAAALGLFYSLRDLHNP 117

Query: 199 GAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLG 258
                    Y  +  + LIA +P + A         G     + +   DD+         
Sbjct: 118 A--------YIRDSVVRLIATIPTMVAAF--QLMRKGN----DPVRPRDDLDYSSNFLYM 163

Query: 259 FELNEFDELM-RLY---LVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLH 314
            +  E D LM R++   L+L  +H   N S  + R+  S L+DPY   A+ +  L GPLH
Sbjct: 164 LDEKEPDPLMARIFDICLILQVEHTM-NASTFSARVTASTLTDPYAVVASAVGTLGGPLH 222

Query: 315 GLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQ 374
           G AN+EV    +QM EK+G    + EN+R      L     I GFGH V +  DPR    
Sbjct: 223 GGANEEV----IQMLEKIG----SVENVRPYIEHCLETKSKIMGFGHRVYKVKDPRAIIL 274

Query: 375 REFALK---HLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVES 431
           +  A K      +D+ + +  ++     RV+ E+   K  +PN+D +SG++ R  G + +
Sbjct: 275 QGLAEKLFEKFGYDKFYDIAQEM----ERVVGEKLGSKGIYPNIDFYSGLVYRKMG-IPT 329

Query: 432 NFYTVLFGVSRALGTLSSLVWDRALGLP-IERPKSV 466
           + +T +F ++R  G L+   W   L    I RP  V
Sbjct: 330 DLFTPIFAIARVAGWLAH--WKEQLAENRIFRPTQV 363


gb|AAL17866.1| citrate synthase [Bacillus methanolicus]
(372 aa)

Score: 100 bits (250), Expect: 7.08874e-20
Length: 331, Idn/Pos/Gap = 96/152/36 (29%/45%/10%)

Query: 127 EGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLL 186
           E +++LL   ++PT+S++E +   L   A +P E+L      P +++HPM     AVSLL
Sbjct:  42 EEVIFLLWHRKLPTKSELEELKILLAENAELPKEILDHFKMYPIDKVHPMAALRSAVSLL 101

Query: 187 QHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKV 246
               + A+   +        E     A+ L A++P++ A   R         P + +   
Sbjct: 102 GLYDEEADLMDE--------EANYRKAIRLQAKIPSIVAAFARVRKGLEPVAPRKDLSFA 153

Query: 247 DDMGMRLARSLGFELNEFD-ELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAG 305
            +    L    G E  +   E     LVLHADHE  N S    R+  + LSD Y    A 
Sbjct: 154 ANFLYMLK---GKEPEDIAVEAFNKVLVLHADHEL-NASTFTARVCVATLSDIYSGVTAA 209

Query: 306 LNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLR 365
           +  L GPLHG AN+ V++ L ++         + EN+     E L +   I GFGH V R
Sbjct: 210 IGALKGPLHGGANEAVMKMLTEIG--------SLENVEPYIREKLAKKEKIMGFGHRVYR 261

Query: 366 RTDPRYTAQREFA-----LKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSG 420
           + DPR    RE +     L   PH   +++ +K+  +V       G+   P PNVD +S 
Sbjct: 262 KGDPRAKHLREMSKKLTELTGEPH--WYEMSTKIEAIV------TGEKGLP-PNVDFYSA 312

Query: 421 ILLRYYGLVESNFYTVLFGVSRALGTLSSLV 451
            +    G ++ + +T +F VSR  G L+ ++
Sbjct: 313 SIYHSLG-IDHDLFTPIFAVSRISGWLAHIL 342


ref|YP_131909.1| putative methylcitrate synthase [Photobacterium profundum SS9]
emb|CAG22109.1| putative methylcitrate synthase [Photobacterium profundum SS9]
(409 aa)

Score: 100 bits (250), Expect: 7.20803e-20
Length: 321, Idn/Pos/Gap = 89/145/30 (27%/45%/9%)

Query: 127 EGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLL 186
           E + +LLL G++PT+ ++++  Q L+    +P  +  +L+ +P    HPM       S+L
Sbjct:  81 EEVAYLLLKGQLPTQRELDNYKQALQTARGLPSALCLVLEAIP-ASAHPMDVMRTGCSML 139

Query: 187 QHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKV 246
            +  +  +   QG           +   TL+A LPA+    YR + HG +   A   +  
Sbjct: 140 GNLDQEYDFSEQG-----------DKTDTLLALLPAIICYWYRYSHHGVRINTANSTQ-- 186

Query: 247 DDMGMRLARSLGFELNE--FDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAA 304
           D +G      L  E     + ++M   LVL+A+HE  N S    R+  S LSD +    A
Sbjct: 187 DSIGGYFLEMLTDEAPSELYKKVMHCSLVLYAEHEF-NASTFTARVCASTLSDLHSCITA 245

Query: 305 GLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVL 364
            +  L GPLHG AN+  +  + Q +        + E       E L     I GFGHA+ 
Sbjct: 246 AIGSLRGPLHGGANEAAMAMIEQWQ--------SAEQAEAGTLEMLANKDKIMGFGHAIY 297

Query: 365 RRTDPRYTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLR 424
           R +DPR    +E++ K L  D      + L+EV  +V +   + K  +PN D        
Sbjct: 298 RESDPRNALIKEWSRK-LSQDVN---DTHLFEVSEKVEQIMKREKGLFPNADFFHASAYH 353

Query: 425 YYGLVESNFYTVLFGVSRALG 445
           + G + +  +T +F +SR  G
Sbjct: 354 FMG-IPTKLFTPIFVMSRVTG 373


ref|ZP_00271857.1| COG0372: Citrate synthase [Ralstonia metallidurans CH34]
(433 aa)

Score: 100 bits (250), Expect: 8.03386e-20
Length: 352, Idn/Pos/Gap = 101/166/41 (28%/47%/11%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPM---TQFSVAVSLLQ 187
           +LLL GE+P   Q E     +     V  ++   L     +  HPM   T    A+S   
Sbjct:  92 YLLLKGELPNAKQKEEFVNSVMNHTMVHEQLQFFLRGFRRD-AHPMAVLTGLVGAMSAFY 150

Query: 188 HESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVD 247
           H++   +   Q              A+ LIA++P + A  Y+ T       P   +    
Sbjct: 151 HDAMDIDDPHQREIS----------AIRLIAKMPTLVAMAYKYTMGQPYIYPQNDLSYSG 200

Query: 248 D-MGMRLARSLG-FELNEFDE--LMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFA 303
           + M M  A     + +N   E  L R++ +LHADHE  N S   VRL GS+ ++P+ + A
Sbjct: 201 NFMRMMFATPCAPYTVNPVLERALDRIF-ILHADHEQ-NASTSTVRLAGSSGTNPFAAIA 258

Query: 304 AGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAV 363
           AG+  L GP HG AN+  L+    M E++G+     E ++++  +    G  + GFGH V
Sbjct: 259 AGVACLWGPAHGGANEAALK----MLEEIGSVDNIGEFIKQV--KDKNSGVRLMGFGHRV 312

Query: 364 LRRTDPRYTAQREFALK-----HLPHDEMFQLVSKLYEVVPRVLEEQGKV-KNPWPNVDQ 417
            +  DPR    RE   +      L +D +F+L  +L ++    LE++  V +  +PNVD 
Sbjct: 313 YKNYDPRAKLMRETCYEVLNELGLHNDPLFKLAMELEKI---ALEDEYFVSRKLYPNVDF 369

Query: 418 HSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPKSV 466
           +SGI+ R  G + ++ +T +F ++R  G +S   W+  +  P   I RP+ +
Sbjct: 370 YSGIVQRALG-IPTSLFTCIFALARTPGWISQ--WEEMITDPEYKIGRPRQL 418


ref|ZP_00290036.1| COG0372: Citrate synthase [Magnetococcus sp. MC-1]
(433 aa)

Score: 100 bits (250), Expect: 8.16905e-20
Length: 423, Idn/Pos/Gap = 113/193/53 (26%/45%/12%)

Query:  65 GEEVLDACTVNQAYG------GMRSLKAMVYETSLLDPQEGIRF-RGFSIPECQRLLPRA 117
           G  V+D     + +G      G RS  +     + +D  +G+   RG+ I +       A
Sbjct:  27 GPPVVDVTKFYKDFGLFTLDPGFRSTGSCRSTITFIDGDKGVLLHRGYPIEQLA-----A  81

Query: 118 KPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMT 177
           K S  +     + +LLL  ++PT+++ +     +     V  ++LR       +  HPM 
Sbjct:  82 KSSFLE-----VCYLLLNEKLPTKAEFDDFDDKITHHTMVHEQLLRFFAGYRRD-AHPMA 135

Query: 178 QFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKH 237
                V  L        A+   A   +  ++    A  LIA++P +AA  Y+  +H G+ 
Sbjct: 136 IMVGVVGALS-------AFYHDALDISDPKHREISAHRLIAKIPTIAACSYK--YHYGQP 186

Query: 238 V--PAEKI---EKVDDMGMRLARSLGFELN-EFDELMRLYLVLHADHEGGNVSAHAVRLV 291
              P  K+   E   +M  R      F+++      M    +LHADHE  N S   VRL 
Sbjct: 187 FVYPNNKMSYAENFLNMTFRTPCDDDFKIDPRLVSAMDKIFILHADHEQ-NASTSTVRLA 245

Query: 292 GSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLR 351
           GS+ ++P+ + +AG++ L GP HG AN+ VL+    M  ++G+     E + +   +   
Sbjct: 246 GSSRANPFAAVSAGISALWGPAHGGANEAVLK----MLGEIGSVERIDEYIAKA--KDPN 299

Query: 352 EGHVIPGFGHAVLRRTDPRYTAQREFALKHL----PHDE-MFQLVSKLYEVVPRVLEEQG 406
           +   + GFGH V +  DPR    +    + L     HDE +F++  KL E+   + ++  
Sbjct: 300 DPFRLMGFGHRVYKNYDPRAAVLKGACQEVLDAVGKHDEPLFKIAMKLEEIA--LNDDYF 357

Query: 407 KVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRAL---GLPIERP 463
             K  +PNVD +SGI+L   G   +N +TV+F ++R +G +S   W   +   G  I RP
Sbjct: 358 ISKKLFPNVDFYSGIILSAMGF-PTNMFTVIFALARTVGWVSQ--WKEMIEEEGQAIGRP 414

Query: 464 KSV 466
           + +
Sbjct: 415 RQL 417


ref|ZP_00039208.1| COG0372: Citrate synthase [Xylella fastidiosa Dixon]
(429 aa)

Score: 100 bits (249), Expect: 9.02932e-20
Length: 346, Idn/Pos/Gap = 95/157/24 (27%/45%/6%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LL+ GE+P + +      ++     +   +   L    H   HPM   + +V+ L    
Sbjct:  89 YLLMNGELPRKDEFAKFDDEITHHTMMHESLKNFLGGF-HYDAHPMAMLAASVASLS--- 144

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDM- 249
               A+          E     A+ LIA++P +AA ++R +       P   +  V+   
Sbjct: 145 ----AFYHDTLDLNDLEQRRLAAIRLIAKVPTLAAAVHRYSIGWPIRYPRNNLGYVERFL 200

Query: 250 -GMRLARSLGFELNEF-DELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLN 307
             M    S   +LN    + + L  +LHADHE  N S   VRLVGS  ++PY S AAG+ 
Sbjct: 201 HMMFEVPSEPLQLNPVVTKALDLLFILHADHEQ-NASTSTVRLVGSTGANPYASVAAGIT 259

Query: 308 GLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRT 367
            L GP HG AN+ VL+    M E++G+       + +   +       + GFGH V +  
Sbjct: 260 ALWGPAHGGANEAVLK----MLEEIGDAKNVDLVIAKAKTKDKNSPFRLMGFGHRVYKHF 315

Query: 368 DPRYTAQREFALKHLP----HDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILL 423
           DPR    RE A   L     +D + ++  KL EV  +  ++    +  +PNVD +SGI+ 
Sbjct: 316 DPRAKIIRETAHTVLGELGVNDPLLEVALKLEEVALK--DDYFVQRKLYPNVDFYSGIIY 373

Query: 424 RYYGLVESNFYTVLFGVSRALGTLSSLVWDRA-LGLPIERPKSVTT 468
           +    +    +TV+F ++R  G +S  +  +    + I RP+ + T
Sbjct: 374 KAIN-IPLEMFTVMFAIARTAGWVSHWLEQQVDPEMKISRPRQIYT 418


ref|ZP_00162660.1| COG0372: Citrate synthase [Anabaena variabilis ATCC 29413]
(378 aa)

Score: 100 bits (249), Expect: 9.73347e-20
Length: 381, Idn/Pos/Gap = 98/179/55 (25%/46%/14%)

Query:  80 GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEI 138
           G+  + A     S +D Q+GI  +RG  I +  +     + +          +LL+ GE+
Sbjct:   9 GLEGIPAAQSSISYVDGQKGILEYRGIRIEDLAQKSTFLETA----------YLLIWGEL  58

Query: 139 PTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQ 198
           PT+ +++   ++++    +   +  ++   P E  HPM     + + L         Y++
Sbjct:  59 PTKEELQVFEEEVRLHRRIKYRIRDMMKCFP-ESGHPMDALQASAAAL------GLFYSR 111

Query: 199 GAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLG 258
               +    Y  +  + LIA +P + A         G     + ++  DD+    + +  
Sbjct: 112 RDLHNPV--YIRDAVVRLIATIPTMVAAF--QLMRKGN----DPVKPRDDLDY--SANFL 161

Query: 259 FELNEFD------ELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGP 312
           + LNE +      ++  + L+LH +H   N S  + R+  S L+DPY   A+ +  L GP
Sbjct: 162 YMLNEKEPDALAAKIFDICLILHVEHTM-NASTFSARVTASTLTDPYAVVASAVGTLGGP 220

Query: 313 LHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYT 372
           LHG AN+EV    +QM E++G    + EN+R    E L+    + GFGH V +  DPR T
Sbjct: 221 LHGGANEEV----IQMLEEIG----SVENVRSYVEERLQRKDKLMGFGHRVYKVKDPRAT 272

Query: 373 AQREFALKHLPHDEMFQL--VSKLYEV---VPRVLEEQGKVKNPWPNVDQHSGILLRYYG 427
             +  A      +++F      K Y++   + RV+EE+   K  +PNVD +SG++ R  G
Sbjct: 273 ILQGLA------EQLFAKFGADKYYDIAQEMERVVEEKLGHKGIYPNVDFYSGLVYRKMG 326

Query: 428 LVESNFYTVLFGVSRALGTLS 448
            + ++ +T +F ++R  G L+
Sbjct: 327 -IPTDLFTPIFAIARVAGWLA 346


gb|AAL01655.1| citrate synthase [Ehrlichia equi]
(411 aa)

Score: 100 bits (249), Expect: 9.81503e-20
Length: 405, Idn/Pos/Gap = 108/181/56 (26%/44%/13%)

Query:  80 GMRSLKAMVYETSLLDPQEG-IRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEI 138
           G  S  A   E + +D  +G +R+RG  I   + L+      G       +++LLL G +
Sbjct:  45 GFMSTAACRSEITFIDGNKGTLRYRGIDI---ENLI------GTPNSFSSIVYLLLNGTL  95

Query: 139 PTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQ---HESKMAEA 195
           P+E++ E   + L     VP +V+ ++   P +  HPM     + S L    H S++   
Sbjct:  96 PSETEHEEFARILGAEYDVPEQVMNVIRSFPRDS-HPMAILIASFSALAANYHASRIDP- 153

Query: 196 YAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLAR 255
                         L  A+  IA++P + A IYR+T +    + A+   +     +R+  
Sbjct: 154 --------------LTGAIIAIAKVPGIVASIYRHTANL-DFIQADANLEYTHHFIRMM- 197

Query: 256 SLGFELNEFDELMRLYL----VLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAG 311
             G   +   ++M   L    ++HADHE  N S   VR+ GS+ +  +    AG+  L G
Sbjct: 198 -FGDMDDAHRDIMHKALDAIFIMHADHEQ-NASTSTVRMTGSSGAGLFACLCAGVATLWG 255

Query: 312 PLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRY 371
           P HG AN+ V++ L ++       P    +  +       +  ++ GFGH V +  DPR 
Sbjct: 256 PAHGGANEAVIKMLAEI-----GSPENVSSFIDKVKNNKGKSRLM-GFGHRVYKSYDPRA 309

Query: 372 TAQREF---ALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNP-WPNVDQHSGILLRYYG 427
              R      L  L  DE    V++  E+  + L+++  ++   +PNVD +SGI+LR  G
Sbjct: 310 RVLRTICKDVLDSLGRDENLLAVAE--ELESQALQDEYFIERKLYPNVDFYSGIVLRAMG 367

Query: 428 LVESNFYTVLFGVSRALGTLSSLVWDRAL----GLPIERPKSVTT 468
            V  + YT  F ++R  G  S   W   +    G  I RP+ + T
Sbjct: 368 -VPVDMYTAFFALARTSGWASQ--WYEMIQSDEGKRISRPRQLYT 409


gb|AAL01658.1| citrate synthase [Anaplasma marginale]
gb|AAL01657.1| citrate synthase [Anaplasma marginale]
ref|YP_154269.1| citrate synthase [Anaplasma marginale str. St. Maries]
gb|AAV87014.1| citrate synthase [Anaplasma marginale str. St. Maries]
(417 aa)

Score: 100 bits (249), Expect: 9.98019e-20
Length: 419, Idn/Pos/Gap = 117/178/82 (27%/42%/19%)

Query:  80 GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEG----LLWLLL 134
           G  S  A   E + +D  EGI R+RG+ I +               + +G    + +LLL
Sbjct:  45 GFMSTAACKSEITFIDGDEGILRYRGYDIADLT-------------MADGGFCSIAYLLL  91

Query: 135 TGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAE 194
            G +P   ++      + R   V  +VL ++  LP +  HPM     + + L        
Sbjct:  92 YGTMPQGRELADFVATVSRECNVRTQVLDVIRALPRD-AHPMAILIASFAALA------- 143

Query: 195 AYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLA 254
           A+  GA         L  A+  I+++P + A IYR+T  G   + A+             
Sbjct: 144 AHYHGANSLD----PLRSAIVAISQVPGIVASIYRHT-SGAPLIEADP------------ 186

Query: 255 RSLGFELN----EFDEL-----------MRLYLVLHADHEGGNVSAHAVRLVGSALSDPY 299
            SLG+  N     F +L           +    ++HADHE  N S   VR  GSA ++ +
Sbjct: 187 -SLGYVQNFVHMMFGDLHETRKSIICKALEAIFIMHADHEQ-NASTATVRATGSAGANLF 244

Query: 300 LSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGF 359
              +AG   L GP HG AN+ V++    M E++G RP       E   E    G  + GF
Sbjct: 245 ACLSAGAATLWGPAHGGANEAVVK----MLEEIG-RPERVGEFIEKVKEK-ESGVRLMGF 298

Query: 360 GHAVLRRTDPRYTAQREFALKHL----PHDEMFQLVSKLYEVVPRVLEEQGKVKNP-WPN 414
           GH V +  DPR    R+   + L      D +  + + L +     LE++  VK   +PN
Sbjct: 299 GHRVYKNYDPRARIIRDICKETLSGLGADDPLLDVATALEKA---ALEDEYFVKRSLYPN 355

Query: 415 VDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRAL-----GLPIERPKSVTT 468
           VD +SGI+L+  G V  N +T  F ++R  G   S  W   L     G  I RP+ + T
Sbjct: 356 VDFYSGIVLKAAG-VPVNMFTAFFALARTTGW--SAQWYEMLDKQHEGSKICRPRQLYT 411


ref|YP_179821.1| citrate synthase [Campylobacter jejuni RM1221]
gb|AAW36273.1| citrate synthase [Campylobacter jejuni RM1221]
emb|CAB73669.1| citrate synthase [Campylobacter jejuni subsp. jejuni NCTC 11168]
ref|NP_282809.1| citrate synthase [Campylobacter jejuni subsp. jejuni NCTC 11168]
pir||G81265 citrate (si)-synthase (EC 4.1.3.7) Cj1682c [similarity] - Campylobacter jejuni (strain NCTC 11168)
(422 aa)

Score: 100 bits (248), Expect: 1.28188e-19
Length: 356, Idn/Pos/Gap = 98/165/30 (27%/46%/8%)

Query: 121 GEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFS 180
            E  L   ++ LLL  E+P  +++E+   ++K+R+ +   + RL D  P +  HPM    
Sbjct:  79 AENKLYLDVVHLLLYKELPDATRLEAFRYEMKKRSFIHEGMHRLFDSFP-DNAHPMAVLQ 137

Query: 181 VAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPA 240
            AVS       ++  Y      +   EY +E A  ++A++P + A  YR   HG      
Sbjct: 138 GAVS------SLSAFYPDHLNMNVKEEY-MEMAARIVAKIPTIVATAYRYK-HGFPMAYP 189

Query: 241 EKIEKVDDMGMRLARSLGFELNEFDEL----MRLYLVLHADHEGGNVSAHAVRLVGSALS 296
                  +  + + R+  ++  E   +    +    +LHADHE  N S   VR VGS  +
Sbjct: 190 NLDRGFTENFLYMLRTYPYDHVELKPIEVKALDTVFMLHADHEQ-NASTSTVRAVGSTHA 248

Query: 297 DPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVI 356
            PY   AAG+  L G  HG AN+ V+R    M E++G+     E ++    +   +   +
Sbjct: 249 HPYACIAAGIGALWGHAHGGANEGVIR----MLEQIGSVDRVDEFIKRA--KDKNDPFRL 302

Query: 357 PGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSKLYEVVPRVLE-----EQGKVKNP 411
            GFGH V +  DPR    ++  L+    DE+  + + L +V  R+ E     +    +  
Sbjct: 303 MGFGHRVYKNFDPRAKVLKK--LRDQLIDEL-GIDTNLIKVATRIEEIALSDDYFVQRGL 359

Query: 412 WPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRAL-GLPIERPKSV 466
           +PNVD HSG++L+  G+    F T LF + R  G ++  +  +    L I RP+ +
Sbjct: 360 YPNVDFHSGLILKALGIPNEMFAT-LFVIGRTPGWIAQWIEQKEQESLKIVRPRQL 414


gb|AAL01654.1| citrate synthase [Anaplasma phagocytophila]
gb|AAR36874.1| citrate synthase [Anaplasma phagocytophilum]
gb|AAR36873.1| citrate synthase [Anaplasma phagocytophilum]
gb|AAR36872.1| citrate synthase [Anaplasma phagocytophilum]
gb|AAR36871.1| citrate synthase [Anaplasma phagocytophilum]
gb|AAR36870.1| citrate synthase [Anaplasma phagocytophilum]
gb|AAR36869.1| citrate synthase [Anaplasma phagocytophilum]
gb|AAR36868.1| citrate synthase [Anaplasma phagocytophilum]
(411 aa)

Score: 100 bits (248), Expect: 1.29262e-19
Length: 405, Idn/Pos/Gap = 108/181/56 (26%/44%/13%)

Query:  80 GMRSLKAMVYETSLLDPQEG-IRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEI 138
           G  S  A   E + +D  +G +R+RG  I   + L+      G       +++LLL G +
Sbjct:  45 GFMSTAACRSEITFIDGNKGTLRYRGIDI---ENLI------GTPNSFSSIVYLLLKGTL  95

Query: 139 PTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQ---HESKMAEA 195
           P+E++ E   + L     VP +V+ ++   P +  HPM     + S L    H S++   
Sbjct:  96 PSETEHEEFVRILGAEYDVPEQVMNVIRSFPRDS-HPMAILIASFSALAANYHASRIDP- 153

Query: 196 YAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLAR 255
                         L  A+  IA++P + A IYR+T +    + A+   +     +R+  
Sbjct: 154 --------------LTGAIIAIAKVPGIVASIYRHTANL-DFIQADANLEYTHHFIRMM- 197

Query: 256 SLGFELNEFDELMRLYL----VLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAG 311
             G   +   ++M   L    ++HADHE  N S   VR+ GS+ +  +    AG+  L G
Sbjct: 198 -FGDMDDAHRDIMHKALDAIFIMHADHEQ-NASTSTVRMTGSSGAGLFACLCAGVATLWG 255

Query: 312 PLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRY 371
           P HG AN+ V++ L ++       P    +  +       +  ++ GFGH V +  DPR 
Sbjct: 256 PAHGGANEAVIKMLAEI-----GSPENVSSFIDKVKNNKGKSRLM-GFGHRVYKSYDPRA 309

Query: 372 TAQREF---ALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNP-WPNVDQHSGILLRYYG 427
              R      L  L  DE    V++  E+  + L+++  ++   +PNVD +SGI+LR  G
Sbjct: 310 RVLRTICKDVLDSLGRDENLLAVAE--ELESQALQDEYFIERKLYPNVDFYSGIVLRAMG 367

Query: 428 LVESNFYTVLFGVSRALGTLSSLVWDRAL----GLPIERPKSVTT 468
            V  + YT  F ++R  G  S   W   +    G  I RP+ + T
Sbjct: 368 -VPVDMYTAFFALARTSGWASQ--WYEMIQSDEGKRISRPRQLYT 409


gb|AAQ58745.1| citrate (si)-synthase [Chromobacterium violaceum ATCC 12472]
ref|NP_900740.1| citrate (si)-synthase [Chromobacterium violaceum ATCC 12472]
(435 aa)

Score: 100 bits (248), Expect: 1.4051e-19
Length: 374, Idn/Pos/Gap = 105/171/69 (28%/45%/18%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LLL GE+PT +Q +   + + R   +  +++ L      +  HPM      V  L    
Sbjct:  96 YLLLNGELPTAAQRKEFERGVMRHNMLHDQLMSLFKGFRRD-AHPMAVMVGVVGALS--- 151

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYR------------------NTF 232
               A+   +   +  E+    A  LIA+LP +AA+ YR                  N  
Sbjct: 152 ----AFYHDSLDISNPEHRRISAHRLIAKLPTIAAQAYRYNKGLPFSYPKNGLTYAENFL 207

Query: 233 HGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVLHADHEGGNVSAHAVRLVG 292
           H     P E+  KV+ +   LAR+L           R++  LHADHE  N S   VRL G
Sbjct: 208 HMMFSTPCEEY-KVNPV---LARALD----------RIF-TLHADHEQ-NASTSTVRLAG 251

Query: 293 SALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLRE 352
           S+ ++P+   AA +  L GP HG AN+ VL+    M +++G    + +N+ +       +
Sbjct: 252 SSGANPFACIAACIACLWGPSHGGANEAVLK----MLDEIG----SVDNVADFMQGVKDK 303

Query: 353 GHVIPGFGHAVLRRTDPRYTAQREFALK-----HLPHDEMFQLVSKLYEVV---PRVLEE 404
            + + GFGH V +  DPR    ++   +      L +D  F+L  +L ++    P  +E 
Sbjct: 304 RYKLMGFGHRVYKNMDPRAAIMKQTCDEVLNELGLHNDPKFKLAMELEKIALSDPYFIE- 362

Query: 405 QGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IE 461
               +  +PNVD +SGI+L   G+  S F T +F ++R +G ++   W+  +G P   I 
Sbjct: 363 ----RKLYPNVDFYSGIVLSAIGIPVSMF-TPIFALARTVGWIAH--WNEMIGDPGMKIG 415

Query: 462 RPKSVTTQWIREHF 475
           RP+ + T   R  F
Sbjct: 416 RPRQLYTGAARRDF 429


ref|NP_343923.1| Citrate synthase [Sulfolobus solfataricus P2]
gb|AAK42713.1| Citrate synthase [Sulfolobus solfataricus P2]
sp|P80148|CISY_SULSO Citrate synthase
pdb|1O7X|D Chain D, Citrate Synthase From Sulfolobus Solfataricus
pdb|1O7X|C Chain C, Citrate Synthase From Sulfolobus Solfataricus
pdb|1O7X|B Chain B, Citrate Synthase From Sulfolobus Solfataricus
pdb|1O7X|A Chain A, Citrate Synthase From Sulfolobus Solfataricus
(377 aa)

Score: 99 bits (247), Expect: 1.54017e-19
Length: 383, Idn/Pos/Gap = 98/171/53 (25%/44%/13%)

Query:  80 GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEI 138
           G+ ++   V   + +D ++GI R+RG++I +                 E  ++L+L G++
Sbjct:   7 GLENVIIKVTNLTFIDGEKGILRYRGYNIEDLVNYGSY----------EETIYLMLYGKL  56

Query: 139 PTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQ 198
           PT+ ++  +   L     VP EVL  +  +P E        + A+ LL+    +  A   
Sbjct:  57 PTKKELNDLKAKLNEEYEVPQEVLDTIYLMPKE--------ADAIGLLE----VGTAALA 104

Query: 199 GAPKSTFW-EYCLEDALTLIARLPAVAARIYRNTFHGGKHVP--AEKIEKVDDMGMRLAR 255
              K+  W E   E A+++IA++  + A +YR        +P  ++   K   +      
Sbjct: 105 SIDKNFKWKENDKEKAISIIAKMATLVANVYRRKEGNKPRIPEPSDSFAKSFLLASFARE 164

Query: 256 SLGFELNEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHG 315
               E+N  D+     L+L+ DHE    S  A  +  S LSD Y S  A L  L GPLHG
Sbjct: 165 PTTDEINAMDKA----LILYTDHEV-PASTTAALVAASTLSDMYSSLTAALAALKGPLHG 219

Query: 316 LANQEVLRWLLQMKEKLGNRPMTTENLRELCW---ETLREGHVIPGFGHAVLRRTDPRYT 372
            A +E  +  +++ +     P   +N     W   + + + + + GFGH V +  DPR  
Sbjct: 220 GAAEEAFKQFIEIGD-----PNRVQN-----WFNDKVVNQKNRLMGFGHRVYKTYDPRAK 269

Query: 373 AQREFALKHLPHD----EMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGL 428
             ++ AL  +  +      F++  KL E+  +    +G     +PN D +SGI+    G 
Sbjct: 270 IFKKLALTLIERNADARRYFEIAQKLEELGIKQFSSKGI----YPNTDFYSGIVFYALGF 325

Query: 429 VESNFYTVLFGVSRALGTLSSLV 451
                +T LF +SR LG L+ ++
Sbjct: 326 -PVYMFTALFALSRTLGWLAHII 347


gb|AAW71323.1| Citrate synthase [Wolbachia endosymbiont strain TRS of Brugia malayi]
ref|YP_198565.1| Citrate synthase [Wolbachia endosymbiont strain TRS of Brugia malayi]
(416 aa)

Score: 99 bits (247), Expect: 1.56609e-19
Length: 361, Idn/Pos/Gap = 93/168/35 (25%/46%/9%)

Query:  92 SLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQD 150
           + +D  EG+ R+RG  I +            +      +++LLL G++P   Q +     
Sbjct:  58 TFIDGDEGVLRYRGHDIADL----------AQSNDFTAVIYLLLYGKLPNLEQHKKFFLK 107

Query: 151 LKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCL 210
           ++  + VP +V+ ++   P +  HPM+      + L   +   E Y             L
Sbjct: 108 IQELSKVPEQVVNVIKAFP-KTAHPMSILIACFATLS--ALYHERYGNNVSNEN-----L 159

Query: 211 EDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNE---FDEL 267
           +  ++ IA++PA+ A +YR+T +  + +  +         +R+      + ++   F + 
Sbjct: 160 DFGISAIAQVPAIIAMVYRHT-NDQEFIDTDNELNYSKSFLRMMFGNALDNDKSTLFAKA 218

Query: 268 MRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQ 327
           +     LHADHE  N S  AVR+VGSA S+ +   +AG+  L GP+HG AN+ V+  L +
Sbjct: 219 LDKIFTLHADHEQ-NASTAAVRVVGSAGSNLFACLSAGVATLWGPVHGGANESVINMLKE 277

Query: 328 MKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFA---LKHLPH 384
           + E+ GN     E  ++      ++   + GFGH V +  DPR    ++     L  L  
Sbjct: 278 I-EQSGNVDKFIEKAKD-----DKDPFKLMGFGHRVYKNYDPRARILKDACDEILNKLEQ 331

Query: 385 DEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRAL 444
           D     ++K  E +  + +E   V+  +PNVD +SGI++    +  S F T +F ++R  
Sbjct: 332 DSKLLKIAKELEKIA-LKDEYFVVRKLYPNVDFYSGIIMNAINIPPSMF-TPIFALARTT 389

Query: 445 G 445
           G
Sbjct: 390 G 390


ref|NP_966867.1| citrate synthase [Wolbachia endosymbiont of Drosophila melanogaster]
gb|AAS14801.1| citrate synthase [Wolbachia endosymbiont of Drosophila melanogaster]
(416 aa)

Score: 99 bits (247), Expect: 1.57921e-19
Length: 362, Idn/Pos/Gap = 95/176/37 (26%/48%/10%)

Query:  92 SLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQD 150
           + +D  EG+ ++RG +I +            E      +++LLL GE+P+  Q +     
Sbjct:  58 TFIDGDEGVLKYRGHNIADL----------AENNNFTAVIYLLLYGELPSSEQHKKFLLK 107

Query: 151 LKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCL 210
           ++  + V  +V  ++   P +  HPM   S+ V+     + ++ +Y +    +   E  L
Sbjct: 108 IQESSKVSEQVTNVIKAFP-KTAHPM---SILVACF---ASLSASYHEKHGNNVNGED-L 159

Query: 211 EDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNE---FDEL 267
           +  ++ IA++  + A IYR+  +  + + A       +  +++      + ++   F + 
Sbjct: 160 DFGISAIAQVSTIIAMIYRH-INNQEFINANNELSYSENFLKMIFGDAVDNDKSALFAKA 218

Query: 268 MRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQ 327
           +     LHADHE  N S  AVRLVGSA S+ + S +AG+  L GP HG AN+ V+  L +
Sbjct: 219 LDKIFTLHADHEQ-NASTAAVRLVGSAGSNLFASLSAGVATLWGPAHGGANEAVINMLKE 277

Query: 328 MKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYT----AQREFALKHLP 383
           + E+ G+     E  ++      ++   + GFGH V +  DPR      A  E   K   
Sbjct: 278 I-EQSGDIDKFIEKAKD-----DKDPFKLMGFGHRVYKNYDPRARILEGACHEVLSKLEQ 331

Query: 384 HDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRA 443
           ++E+ ++  KL E+  +  +E   V+  +PNVD +SGI++     + SN +T +F ++R 
Sbjct: 332 NNELLKIAKKLEEIALK--DEYFIVRKLYPNVDFYSGIIMNAID-IPSNMFTPIFALART 388

Query: 444 LG 445
            G
Sbjct: 389 TG 390


ref|NP_683183.1| citrate synthase [Thermosynechococcus elongatus BP-1]
dbj|BAC09945.1| citrate synthase [Thermosynechococcus elongatus BP-1]
(382 aa)

Score: 99 bits (247), Expect: 1.64648e-19
Length: 405, Idn/Pos/Gap = 109/176/49 (26%/43%/12%)

Query:  71 ACTVNQAYGGMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGL 129
           AC  +    G+   ++ +   S +D Q GI  +RG  I E            E+      
Sbjct:   3 ACEFSPGLDGIPVAQSAI---SYVDGQAGILEYRGVPIQEL----------AEKSTFLET  49

Query: 130 LWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHE 189
            +LL+ G  P   ++ +   D+     V   +  ++   P E  HPM     +   L   
Sbjct:  50 AFLLIWGYWPNREELAAFEHDITYHRRVKYRIRDMMKCFP-ESGHPMDALQASAGAL--- 105

Query: 190 SKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDM 249
                 Y++ A +    EY     + L+A++P + A            +P ++++   + 
Sbjct: 106 ---GLFYSRRALEDP--EYIRAAVIRLLAKIPTMVAAFQLIRKGNDPVMPCDELDYAANF 160

Query: 250 GMRL--ARSLGFELNEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLN 307
              L   R   F    FD    + L+LHA+H   N S  + R+  S L+DPY   A+ + 
Sbjct: 161 LYMLNERRPDPFAARVFD----ICLILHAEHTM-NASTFSARVTASTLTDPYAVVASAVG 215

Query: 308 GLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRT 367
            LAGPLHG AN++V    + M E++G    + EN+R    + ++    I GFGH V +  
Sbjct: 216 TLAGPLHGGANEDV----INMLEEIG----SVENVRPYVEKCIQNKIKIAGFGHRVYKVK 267

Query: 368 DPRYTAQREFA---LKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLR 424
           DPR T  ++ A         D  + +  KL EVV   L  +G     +PNVD +SG++ R
Sbjct: 268 DPRATILQKLAEQLFDKFGGDRYYDIALKLEEVVGEYLSYKGI----YPNVDFYSGLVYR 323

Query: 425 YYGLVESNFYTVLFGVSRALGTLSSLVWDRAL-GLPIERPKSVTT 468
             G + S+ +T +F ++R  G L+   W   L    I RP  V T
Sbjct: 324 RLG-IPSDLFTPVFAIARVAGWLAH--WKEQLEANRIYRPTQVYT 365


ref|NP_967540.1| hypothetical protein Bd0562 [Bdellovibrio bacteriovorus HD100]
emb|CAE78533.1| citZ [Bdellovibrio bacteriovorus HD100]
(379 aa)

Score: 99 bits (247), Expect: 1.64648e-19
Length: 350, Idn/Pos/Gap = 95/161/38 (27%/46%/10%)

Query:  98 EGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAV 157
           + + FRG++I +       A  + E+     + +LL   ++P   ++ +    L+   A+
Sbjct:  31 DSLNFRGYTIDDLA-----ANSTFEE-----VTYLLWNDKLPNAQELAAFSTQLRNEMAL  80

Query: 158 PPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLI 217
            P+ +++L  +P   +HPM     AVSL+ H    ++A   GA      E  L  ++ L 
Sbjct:  81 SPDFIKVLKAIP-TNVHPMGWLRTAVSLMAHWD--SDANDNGA------EANLRKSVRLT 131

Query: 218 ARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELN-EFDELMRLYLVLHA 276
           A++  +      +    GK   A K +K     M      G E   E  ++M   L+LHA
Sbjct: 132 AKMGTLLCAF--DAIRKGKEPVAPKADKSMAWNMMYMLGGGAEPKAEHVKVMDTCLILHA 189

Query: 277 DHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRP 336
           DHE  N SA A R+  S+LSD + +  + +  L GPLHG AN++V    + M +K+G   
Sbjct: 190 DHEL-NCSAFATRVTASSLSDLHSAIVSAIGALKGPLHGGANEQV----ILMLQKIG--- 241

Query: 337 MTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSKLYE 396
            T E  ++   + L     + G GH V +  DPR    R  + K L  D     +  +YE
Sbjct: 242 -TMEKAQQFVKDALAAKEKVMGIGHRVYKNGDPRARILRGMSDK-LTKDAG---IHHMYE 296

Query: 397 VVPRVLEEQGKVKNPWPNVDQHSGILLRYYGL-VESNFYTVLFGVSRALG 445
           +   + +     K   PNVD +S  +  Y+ + + ++ +T +F  SR  G
Sbjct: 297 MSTLIDDTMFNEKGLMPNVDFYSATV--YFSMGIPTDLFTPIFAASRISG 344


emb|CAB14345.1| citrate synthase III [Bacillus subtilis subsp. subtilis str. 168]
ref|NP_390294.1| citrate synthase III [Bacillus subtilis subsp. subtilis str. 168]
gb|AAB09616.1| citrate synthase III [Bacillus subtilis]
pir||E69658 citrate synthase III mmgD - Bacillus subtilis
sp|P45858|CISY3_BACSU Citrate synthase III
dbj|BAA12590.1| YqiO [Bacillus subtilis]
(372 aa)

Score: 99 bits (246), Expect: 2.06251e-19
Length: 378, Idn/Pos/Gap = 104/172/37 (27%/45%/9%)

Query:  80 GMRSLKAMVYETSLLDPQEG-IRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEI 138
           G+  + A     S LD Q   I  RG+ + E    L   K   E      L+ LLL G +
Sbjct:  10 GLDGVIAAETHISYLDTQSSQILIRGYDLIE----LSETKSYLE------LVHLLLEGRL  59

Query: 139 PTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQ 198
           P ES++E++ + +   +++P + LRLL+ LP E  HPM      +S L    +  +  + 
Sbjct:  60 PEESEMETLERKINSASSLPADHLRLLELLP-EDTHPMDGLRTGLSALAGYDRQIDDRSP 118

Query: 199 GAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLG 258
            A K        E A  L+ ++PA+ A  YR        +P + +    +    +   L 
Sbjct: 119 SANK--------ERAYQLLGKMPALTAASYRIINKKEPILPLQTLSYSANFLYMMTGKLP 170

Query: 259 FELNEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLAN 318
             L E  ++    LVL+++HE  N S  A R++ S  SD Y +    +  L G LHG AN
Sbjct: 171 SSLEE--QIFDRSLVLYSEHEMPN-STFAARVIASTHSDLYGALTGAVASLKGNLHGGAN 227

Query: 319 QEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAV-LRRTDPRYTAQREF 377
           + V+  LL+ K        TT +  +L    L+    I GFGH V +++ DPR    +E 
Sbjct: 228 EAVMYLLLEAK--------TTSDFEQLLQTKLKRKEKIMGFGHRVYMKKMDPRALMMKE- 278

Query: 378 ALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVL 437
           AL+ L        + ++ E   R++E++   K  +PN+D ++  +    G +    YT +
Sbjct: 279 ALQQLCDKAGDHRLYEMCEAGERLMEKE---KGLYPNLDYYAAPVYWMLG-IPIPLYTPI 334

Query: 438 FGVSRALGTLSSLVWDRA 455
           F  +R  G  + ++   A
Sbjct: 335 FFSARTSGLCAHVIEQHA 352


ref|ZP_00370752.1| citrate synthase I [Campylobacter coli RM2228]
gb|EAL56138.1| citrate synthase I [Campylobacter coli RM2228]
(422 aa)

Score: 99 bits (246), Expect: 2.20488e-19
Length: 399, Idn/Pos/Gap = 105/181/43 (26%/45%/10%)

Query:  80 GMRSLKAMVYETSLLDPQEGIRF-RGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEI 138
           G+ S      + + +D +EG+   RG+ I              E  L   ++ LLL  E+
Sbjct:  47 GLTSTATCKSKITYIDGEEGVLMHRGYPIEWL----------AENKLFLDVVHLLLYKEL  96

Query: 139 PTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQ 198
           P+  ++E+   +LK+R+ +   + RL D  P +  HPM     AVS L        A+  
Sbjct:  97 PSNERLEAFRYELKKRSYIHEGMHRLFDSFP-DNAHPMAVLQGAVSSLS-------AFYP 148

Query: 199 GAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEK-VDDMGMRLARSL 257
                   E  +E A  ++A++P + A  YR  +  G  +    +++   +  + + R+ 
Sbjct: 149 DHLNMNVREEYMEMAARVVAKIPTIVAAAYR--YKNGFPMAYPNLDRGFTENFLYMLRTY 206

Query: 258 GFELNEFDEL----MRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPL 313
            ++  E   +    +    +LHADHE  N S   VR VGS  + PY   +AG+  L G  
Sbjct: 207 PYDHVELKPIEVKALDTVFMLHADHEQ-NASTSTVRAVGSTHAHPYACISAGIGALWGHA 265

Query: 314 HGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTA 373
           HG AN+ V+R    M E++       E ++    +   +   + GFGH V +  DPR   
Sbjct: 266 HGGANEGVIR----MLEEIATVDRVDEFIKRA--KDKNDPFRLMGFGHRVYKNFDPRAKV 319

Query: 374 QREFALKHLPHDEMFQLVSKLYEVVPRVLE-----EQGKVKNPWPNVDQHSGILLRYYGL 428
            ++  L+    DE+  + + L +V  R+ E     +    +N +PNVD HSG++L+  G+
Sbjct: 320 LKK--LRDQLIDEL-GIDTNLIKVATRIEEIALQDDYFVQRNLYPNVDFHSGLILKALGI 376

Query: 429 VESNFYTVLFGVSRALGTLSSLVWDRAL-GLPIERPKSV 466
               F T LF + R  G ++  +  +    L I RP+ +
Sbjct: 377 PNEMFAT-LFVIGRTPGWIAQWIEQKEQETLKIVRPRQL 414


ref|ZP_00280973.1| COG0372: Citrate synthase [Burkholderia fungorum LB400]
(413 aa)

Score: 98 bits (245), Expect: 2.51978e-19
Length: 357, Idn/Pos/Gap = 98/161/51 (27%/45%/14%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LLL GE+P   Q     + +     V            HE+MH   +        +   
Sbjct:  72 YLLLKGELPNAQQNAEFVKTVTNHTMV------------HEQMHFFFR-----GFRRDAH 114

Query: 191 KMAEAYAQGAPKSTFWEYCLE---------DALTLIARLPAVAARIYRNTFHGGKHVPAE 241
            MA   A     S F+   L+          A+ +IA+LP + A  Y+ +       P  
Sbjct: 115 PMAILVAAVGALSAFYHDSLDINNPRHREVSAIRMIAKLPTLVAMAYKYSIGQPFAYPKN 174

Query: 242 KIEKVDDMGMRLARSLGFELNEFDELMRLY---LVLHADHEGGNVSAHAVRLVGSALSDP 298
            +    +    +  +   E    D L+R     L+LHADHE  N S   VRL GS+ ++P
Sbjct: 175 DLSYSANFMHMMFSNPCEEYKVNDVLVRALDRILILHADHEQ-NASTSTVRLAGSSGANP 233

Query: 299 YLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPG 358
           +   AAG+  L GP HG AN+      L M E++G+     E ++++  +    G  + G
Sbjct: 234 FACIAAGIACLWGPAHGGANEAA----LNMLEEIGSVDNIPEFIKQV--KDKNSGVKLMG 287

Query: 359 FGHAVLRRTDPRYTAQREFALKHLP----HDE-MFQLVSKLYEVVPRVLEEQGKV-KNPW 412
           FGH V +  DPR    RE   + L     HD+ +F+L   L ++    LE++  V +  +
Sbjct: 288 FGHRVYKNYDPRAKLMRETCHEVLEELGLHDDPLFKLAMALEKI---ALEDEYFVSRKLY 344

Query: 413 PNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPKSV 466
           PNVD +SGI+ R  G + ++ +T +F ++R +G ++   W+  +  P   I RP+ +
Sbjct: 345 PNVDFYSGIVQRALG-IPTSMFTCIFAMARTVGWIAQ--WNEMIADPEQKIGRPRQL 398


gb|AAM92490.1| citrate synthase [Dictyostelium discoideum]
gb|EAL73165.1| citrate synthase [Dictyostelium discoideum]
(492 aa)

Score: 98 bits (245), Expect: 2.80848e-19
Length: 409, Idn/Pos/Gap = 100/175/42 (24%/42%/10%)

Query:  80 GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEI 138
           G ++   +    + +D  +GI R+RG+ I E            E+     + +LL+ G +
Sbjct:  81 GFQNTAVVTSYITYIDGDKGILRYRGYPIEEL----------AERSNFLEVAYLLINGNL 130

Query: 139 PTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQ 198
           P +SQ++     +     +   ++ L+    ++  HPM      V+ L      A     
Sbjct: 131 PNKSQLDGWSNKIMTHTFLHENLVGLMKTFRYD-AHPMGMLISTVAALGTFYPEANPALA 189

Query: 199 GAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLG 258
           G           +    ++ +LP +AA  +R+      + P   +   ++    L +   
Sbjct: 190 GGDIFKSENVRNKQIYRIVGKLPTIAACAWRHRIGRPYNTPVNHLGYTENFLYMLDK--- 246

Query: 259 FELNEFD--------ELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLA 310
             L+E D          + +  +LHADHE  N S  A+R + S+ +DPY S A     L 
Sbjct: 247 --LSEPDYKPNPVLCRALEILFILHADHEL-NCSTAAMRHISSSGTDPYTSVAGAAGALY 303

Query: 311 GPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPR 370
           GP HG AN+ VL  L+ +  K        EN+ +   +   +   + GFGH + +  DPR
Sbjct: 304 GPSHGGANEAVLDMLIHIGSK--------ENIPQFISDVKSKKKKLMGFGHRIYKNYDPR 355

Query: 371 YTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKV-KNPWPNVDQHSGILLRYYGLV 429
               R  A +         L+    E+  + LE++  V +  +PNVD +SG++ +  G  
Sbjct: 356 AKIIRRVAYEVFESLGKEPLIEVATELEKQALEDEYFVSRKLYPNVDFYSGLIYKAMGF- 414

Query: 430 ESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPKSV-TTQWIREH 474
            ++ + VLF + RA+G L+   W   L  P   I RP+ V   +W R +
Sbjct: 415 PTDMFPVLFTIPRAVGWLAH--WVEHLEDPETKIYRPRQVYKGEWFRNY 461


gb|AAL01656.1| citrate synthase [Anaplasma phagocytophila]
(411 aa)

Score: 98 bits (245), Expect: 3.0275e-19
Length: 407, Idn/Pos/Gap = 109/182/60 (26%/44%/14%)

Query:  80 GMRSLKAMVYETSLLDPQEG-IRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEI 138
           G  S  A   E + +D  +G +R+RG  I   + L+      G       +++LLL G +
Sbjct:  45 GFMSTAACRSEITFIDGNKGTLRYRGIDI---ENLI------GTPNSFSSIVYLLLKGTL  95

Query: 139 PTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQ---HESKMAEA 195
           P+E++ E   + L     VP +V+ ++   P +  HPM     + S L    H S++   
Sbjct:  96 PSETEHEEFARILGAEYDVPEQVMNVIRSFPRDS-HPMAILIASFSALAANYHASRIDP- 153

Query: 196 YAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLAR 255
                         L  A+  IA++P + A IYR+T +    + A+   +     +R+  
Sbjct: 154 --------------LTGAIIAIAKVPGIVASIYRHTANL-DFIQADANLEYTHHFIRMM- 197

Query: 256 SLGFELNEFDELMRLYL----VLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAG 311
             G   +   ++M   L    ++HADHE  N S   VR+ GS+ +  +    AG+  L G
Sbjct: 198 -FGDMDDAHRDIMHKALDAIFIMHADHEQ-NASTSTVRMSGSSGAGLFACLCAGVATLWG 255

Query: 312 PLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELC--WETLREGHVIPGFGHAVLRRTDP 369
           P HG AN+ V++ L ++         + EN+       +  +  + + GFGH V +  DP
Sbjct: 256 PAHGGANEAVIKMLAEIG--------SPENVSSFIDKVKNNKGKNRLMGFGHRVYKSYDP 307

Query: 370 RYTAQREF---ALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNP-WPNVDQHSGILLRY 425
           R    R      L  L  DE    V++  E+  + L ++  ++   +PNVD +SGI+LR 
Sbjct: 308 RARVLRTICKDVLDSLGRDENLLAVAE--ELESQALRDEYFIERKLYPNVDFYSGIVLRA 365

Query: 426 YGLVESNFYTVLFGVSRALGTLSSLVWDRAL----GLPIERPKSVTT 468
            G V  + YT  F ++R  G  S   W   +    G  I RP+ + T
Sbjct: 366 MG-VPVDMYTAFFALARTSGWASQ--WYEMIQSDEGKRISRPRQLYT 409


ref|NP_102398.1| citrate synthase [Mesorhizobium loti MAFF303099]
dbj|BAB48184.1| citrate synthase [Mesorhizobium loti MAFF303099]
(433 aa)

Score: 98 bits (245), Expect: 3.2636e-19
Length: 448, Idn/Pos/Gap = 117/188/77 (26%/41%/17%)

Query:  55 AQVHEVRER---FGEEVLDACTVNQAYG------GMRSLKAMVYETSLLDPQEGIRF-RG 104
            + HE + R    G +V+D  ++    G      G  S  +   E + +D   GI   RG
Sbjct:  16 GKTHEFKVRSGSVGPDVIDIASLYSTTGAFTYDPGFTSTASCESEITFIDGDAGILLHRG  75

Query: 105 FSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRL 164
           + I +            E      + +LLL GE+PT++Q +     + R   V  ++ R 
Sbjct:  76 YPIDQL----------AEHGDFLEVCYLLLYGELPTKAQKDDFDYRVTRHTMVHEQMSRF 125

Query: 165 LDELPHERMHPMTQFSV---AVSLLQHESK-MAEAYAQGAPKSTFWEYCLEDALTLIARL 220
                 +  HPM        A+S   H+S  +++ Y +           +  ++ LIA++
Sbjct: 126 FTGFRRD-AHPMAVMCGVVGALSAFYHDSTDISDPYQR-----------MVASMRLIAKM 173

Query: 221 PAVAARIYRNTFHGGKHVPAEKIEKVDDMGMR---LARSLGFELNEFD------ELMRLY 271
           P +AA  Y+       H+    I   +D+G     L         E+         M   
Sbjct: 174 PTIAAMAYK------YHIGQPFIYPKNDLGFAANFLHMCFAVPCEEYKINPVLARAMERI 227

Query: 272 LVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEK 331
            +LHADHE  N S   VRL GS+ ++P+   AAG+  L GP HG AN+      L M  +
Sbjct: 228 FILHADHEQ-NASTSTVRLAGSSGANPFACIAAGIACLWGPAHGGANEAA----LNMLGE 282

Query: 332 LGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRY-----TAQR---EFALKHLP 383
           +G+     E +     +   +   + GFGH V +  DPR      TA     E  +K  P
Sbjct: 283 IGHVDHIPEFIARA--KDKNDPFRLMGFGHRVYKNYDPRAKIMQKTAHEVLGELGIKDDP 340

Query: 384 HDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRA 443
             ++   + K+    P  +E     K  +PNVD +SGI L+  G   +  +TVLF V+R 
Sbjct: 341 LLDIAMELEKIALTDPYFIE-----KKLYPNVDFYSGITLKALGF-PTTMFTVLFAVART 394

Query: 444 LGTLSSLVWDRALGLP---IERPKSVTT 468
           +G ++   W   +  P   I RP+ + T
Sbjct: 395 VGWIAQ--WKEMIEDPRQKIGRPRQLYT 420


ref|NP_222744.1| CITRATE SYNTHASE [Helicobacter pylori J99]
gb|AAD05606.1| CITRATE SYNTHASE [Helicobacter pylori J99]
pir||D71982 citrate synthase - Helicobacter pylori (strain J99)
sp|Q9ZN37|CISY_HELPJ Citrate synthase
(426 aa)

Score: 98 bits (244), Expect: 3.31851e-19
Length: 363, Idn/Pos/Gap = 107/172/56 (29%/47%/15%)

Query: 132 LLLTGEIPTESQVESVC--QDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQ-- 187
           LLLTGE+P ++Q ES+    +L+ R+ V   +L +    P    HPM + S  VS+L   
Sbjct:  88 LLLTGELP-KNQDESLEFELELRHRSFVHESLLNMFSAFP-SNAHPMAKLSSGVSILSTL 145

Query: 188 ---HESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIE 244
              H++   E   Q              A  ++A++P +AA  YRN        P     
Sbjct: 146 YSTHQNMHTEEDYQTM------------ARRIVAKIPTLAAICYRNEVGAPIIYPDIARS 193

Query: 245 KVDDM-----GMRLAR-------SLG---FELNEFDELMRLYLVLHADHEGGNVSAHAVR 289
            V+++     G   +R        +G    E+  FD++    L LHADH G N S+  VR
Sbjct: 194 YVENILFMLRGYPYSRLKHTTQGEVGITPLEVEAFDKI----LTLHADH-GQNASSTTVR 248

Query: 290 LVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWET 349
            V S    PY + +AG++ L G LHG AN++V   LLQ+ E++G+     + +  +  + 
Sbjct: 249 NVASTGVHPYAAISAGISALWGHLHGGANEKV---LLQL-EEIGDVKNVDKYIARV--KD 302

Query: 350 LREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSKLYEVVPRVLE-----E 404
             +   + GFGH V +  DPR  A+    LK   H +  ++  +L E+  +V E     E
Sbjct: 303 KNDNFKLMGFGHRVYKSYDPR--AKILKGLKDELHQKGVKMDERLSEIAAKVEEIALKDE 360

Query: 405 QGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWD-RALGLPIERP 463
               +N +PNVD +SG +LR    +   F+T +F + R +G  + L+   ++    I RP
Sbjct: 361 YFIERNLYPNVDFYSGTILRALK-IPVRFFTPVFVIGRTVGWCAQLLEHVKSPQARITRP 419

Query: 464 KSV 466
           + V
Sbjct: 420 RQV 422


ref|ZP_00146643.2| COG0372: Citrate synthase [Psychrobacter sp. 273-4]
(426 aa)

Score: 98 bits (244), Expect: 3.31851e-19
Length: 358, Idn/Pos/Gap = 93/157/34 (25%/43%/9%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           + L+ G++P   Q     + +++   V  ++ +  +    +  HPM      V  L    
Sbjct:  87 YALIHGDLPNAEQKADFYEKIRKHMGVHDQLRKFFEGFRRD-AHPMAIMVGVVGALS--- 142

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDD-- 248
               A+       +  E+    A+ LIA++P +AA  Y+ +       P       ++  
Sbjct: 143 ----AFYHENLDISNEEHREITAIRLIAKMPTLAAMSYKYSKGEPFMYPRNDFNYAENFL 198

Query: 249 -MGMRLARSLGFELNE-FDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGL 306
            M       + ++ N+     M     LHADHE  N S   VRL GS  ++PY   AAG+
Sbjct: 199 YMMFATPADVNYKTNDVITRAMDKIFTLHADHEQ-NASTSTVRLAGSTGANPYACIAAGI 257

Query: 307 NGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRR 366
             L GP HG AN+ V    L+M +++G    + EN+ E   +       + GFGH V + 
Sbjct: 258 AALWGPSHGGANEAV----LEMLDEIG----SVENVPEFMEKVKSREVKLMGFGHRVYKN 309

Query: 367 TDPRYTAQREFALKHL-------PHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHS 419
            DPR    +E   + L       P  E+   + K+    P  +E     +N +PNVD +S
Sbjct: 310 FDPRAQVMKETCDEVLGALGINDPKLELAMALEKIALEDPFFVE-----RNLYPNVDFYS 364

Query: 420 GILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLPIERPKSVTTQWIREHFEK 477
           GI+L+  G + ++ +TV+F ++R  G +S  +   +    I RP+ + T      F K
Sbjct: 365 GIILKAIG-IPTSMFTVIFSLARTSGWISHWLEMHSTPFKIGRPRQLYTGETHRDFVK 421


ref|NP_298824.1| citrate synthase [Xylella fastidiosa 9a5c]
gb|AAF84344.1| citrate synthase [Xylella fastidiosa 9a5c]
pir||D82669 citrate synthase XF1535 [imported] - Xylella fastidiosa  (strain 9a5c)
(429 aa)

Score: 98 bits (243), Expect: 4.83067e-19
Length: 346, Idn/Pos/Gap = 94/155/24 (27%/44%/6%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LL+ GE+P + +      ++     +   +   L    H   HPM   + +V+ L    
Sbjct:  89 YLLMNGELPRKDEFAKFDDEITHHTMMHESLKNFLGGF-HYDAHPMAMLAASVASLS--- 144

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDM- 249
               A+          E     A+ LIA++P +AA  +R +       P   +  V+   
Sbjct: 145 ----AFYHDTLDLNDLEQRRLAAIRLIAKVPTLAAAAHRYSIGWPIRYPRNNLGYVERFL 200

Query: 250 -GMRLARSLGFELNEF-DELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLN 307
             M    S   +LN    + + L  +LHADHE  N S   VRLVGS  ++PY S AAG+ 
Sbjct: 201 HMMFEVPSEPLQLNPVVTKALDLLFILHADHEQ-NASTSTVRLVGSTGANPYASVAAGIT 259

Query: 308 GLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRT 367
            L GP HG AN+ VL+    M E++G+       + +   +       + GFGH V +  
Sbjct: 260 ALWGPAHGGANEAVLK----MLEEIGDAKNVDLVIAKAKTKDKNSPFRLMGFGHRVYKHF 315

Query: 368 DPRYTAQREFALKHLP----HDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILL 423
           DPR    RE A   L     +D + ++  KL E   +  ++    +  +PNVD +SGI+ 
Sbjct: 316 DPRAKIIREMAHTVLGELGVNDPLLEVALKLEEAALK--DDYFVQRKLYPNVDFYSGIIY 373

Query: 424 RYYGLVESNFYTVLFGVSRALGTLSSLVWDRA-LGLPIERPKSVTT 468
           +    +    +TV+F ++R  G +S  +  +    + I RP+ + T
Sbjct: 374 KAIN-IPLEMFTVMFAIARTAGWVSHWLEQQVDPEMKISRPRQIYT 418


ref|ZP_00245265.1| COG0372: Citrate synthase [Rubrivivax gelatinosus PM1]
(437 aa)

Score: 98 bits (243), Expect: 4.87115e-19
Length: 351, Idn/Pos/Gap = 98/164/36 (27%/46%/10%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LLL GE+P  ++     + +     V  ++   L     +  HPM   +  V  L    
Sbjct:  92 YLLLNGELPNVTEKAKFVKTVNGHTMVNEQMQFFLRGFRRD-AHPMAVLTGLVGGLS--- 147

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMG 250
               A+   +      E+    A+ LIA++P + A  Y+ +       P   +    +  
Sbjct: 148 ----AFYHDSTDVQNPEHRAIAAIRLIAKMPTLVAMAYKYSIGQPYIYPRNDLSYTSNF- 202

Query: 251 MRLARSLGFELNEF---DELMRLY---LVLHADHEGGNVSAHAVRLVGSALSDPYLSFAA 304
           MR+    G    E+   D L+R      +LHADHE  N S   VRL GS+ ++P+ + AA
Sbjct: 203 MRMM--FGTPCEEYVPNDVLVRAMDRIFILHADHEQ-NASTSTVRLCGSSGTNPFAAIAA 259

Query: 305 GLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVL 364
           G+  L GP HG AN+  L  +L+  +K+G      + + ++  +    G  + GFGH V 
Sbjct: 260 GVACLWGPAHGGANEACLN-MLEDIQKMGGVAKVGKFIEQV--KDKNSGVRLMGFGHRVY 316

Query: 365 RRTDPRYTAQRE-----FALKHLPHDEMFQLVSKLYEVVPRVLEEQGKV-KNPWPNVDQH 418
           +  DPR    RE      A   L +D +F+L  +L ++    LE+   V +  +PNVD +
Sbjct: 317 KNYDPRAKLMRETCHEVLAEMGLQNDPLFKLAMELEKI---ALEDDYFVSRKLYPNVDFY 373

Query: 419 SGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPKSV 466
           SGI+ R  G+  S  +T +F ++R +G ++ L  +  +G P   I RP+ +
Sbjct: 374 SGIVQRAIGIPVS-LFTAIFALARTVGWIAQL--NEMIGDPEYKIGRPRQL 421


ref|ZP_00042179.1| COG0372: Citrate synthase [Xylella fastidiosa Ann-1]
(429 aa)

Score: 98 bits (243), Expect: 5.29502e-19
Length: 346, Idn/Pos/Gap = 94/155/24 (27%/44%/6%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LL+ GE+P + +      ++     +   +   L    H   HPM   + +V+ L    
Sbjct:  89 YLLMNGELPRKDEFAKFDDEITHHTMMHESLKNFLGGF-HYDAHPMAMLAASVASLS--- 144

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDM- 249
               A+          E     A+ LIA++P +AA  +R +       P   +  V+   
Sbjct: 145 ----AFYHDTLDLNDLEQRRLAAIRLIAKVPTLAAAAHRYSIGWPIRYPRNNLGYVERFL 200

Query: 250 -GMRLARSLGFELNEF-DELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLN 307
             M    S   +LN    + + L  +LHADHE  N S   VRLVGS  ++PY S AAG+ 
Sbjct: 201 HMMFEVPSEPLQLNPVVTKALDLLFILHADHEQ-NASTSTVRLVGSTGANPYASVAAGIT 259

Query: 308 GLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRT 367
            L GP HG AN+ VL+    M E++G+       + +   +       + GFGH V +  
Sbjct: 260 ALWGPAHGGANEAVLK----MLEEIGDAKNVDLVIAKAKTKDKNSPFRLMGFGHRVYKHF 315

Query: 368 DPRYTAQREFALKHLP----HDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILL 423
           DPR    RE A   L     +D + ++  KL E   +  ++    +  +PNVD +SGI+ 
Sbjct: 316 DPRAKIIREMAHTVLGELGVNDPLLEVALKLEEAALK--DDYFVQRKLYPNVDFYSGIIY 373

Query: 424 RYYGLVESNFYTVLFGVSRALGTLSSLVWDRA-LGLPIERPKSVTT 468
           +    +    +TV+F ++R  G +S  +  +    + I RP+ + T
Sbjct: 374 KAIN-IPLEMFTVMFAIARTAGWVSHWLEQQVDPEMKISRPRQIYT 418


ref|NP_376473.1| hypothetical citrate synthase [Sulfolobus tokodaii str. 7]
dbj|BAB65582.1| 373aa long hypothetical citrate synthase [Sulfolobus tokodaii str. 7]
(373 aa)

Score: 97 bits (242), Expect: 6.52317e-19
Length: 379, Idn/Pos/Gap = 103/169/47 (27%/44%/12%)

Query:  80 GMRSLKAMVYETSLLDPQEG-IRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEI 138
           G+  +     E + +D + G + +RG+SI +            E    E + +L+L G++
Sbjct:   6 GLEDVYVKETEITYIDGELGRLYYRGYSIYDL----------AEFSNFEEVSYLILYGKL  55

Query: 139 PTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQ 198
           P   ++    + L+    +P  +++ L E+  +   PM     AVSLL            
Sbjct:  56 PNREELNWFQEKLREERYLPDFIIKFLREV-RKDAQPMDILRTAVSLL------------ 102

Query: 199 GAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHV--PAEKIEKVDDMGMRLARS 256
           G   S   E      + LI++ P + A   R     G  +  P  K+   ++    L   
Sbjct: 103 GIEDSKNDERTDIKGIKLISKFPTIVANYAR--LRKGLDIIEPDPKLSHSENF---LYML 157

Query: 257 LGFELNEF-DELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHG 315
            G   NE   + M + L+LH DHE  N S  A  +V S  SD Y S  AG++ L GPLHG
Sbjct: 158 YGDRPNEIKSKAMDVTLILHIDHEM-NASTFASLVVASTFSDLYSSIVAGISALKGPLHG 216

Query: 316 LANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQR 375
            AN E L+    M +++G    + E + +     L     I GFGH V +  DPR    +
Sbjct: 217 GANYEALK----MFKEIG----SPEKVNDYILNRLSNKQRIMGFGHRVYKTYDPRARILK 268

Query: 376 EFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNP---WPNVDQHSGILLRYYGLVESN 432
           ++A K L   E  ++ + LY++  +V E   K   P   +PNVD  S I+    G  E +
Sbjct: 269 QYA-KLLAEKEGGEIYT-LYQIAEKVEEIGIKYLGPKGIYPNVDFFSSIVFYSLGF-EPD 325

Query: 433 FYTVLFGVSRALGTLSSLV 451
           F+  +F  +R +G ++ ++
Sbjct: 326 FFPAVFASARVVGWVAHIM 344


gb|AAM49624.1| citrate synthase [Rickettsia sp. IO1]
(411 aa)

Score: 97 bits (242), Expect: 6.91551e-19
Length: 427, Idn/Pos/Gap = 108/193/56 (25%/45%/13%)

Query:  60 VRERFGEEVLDACTVNQAYG------GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQR 112
           ++   GE+V+D   V+          G  S  +     + +D  +GI R RG+ I     
Sbjct:  19 LKASIGEDVIDISRVSAEADCFTYDPGFMSTASCQSTITYIDGDKGILRHRGYDI-----  73

Query: 113 LLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHER 172
                K   E+     + +LL+ GE+P+  Q  +  + +   + V  E L  L +     
Sbjct:  74 -----KDLAEKSDFLEVAYLLIYGELPSSEQYNNFTKQVAHHSLVN-ERLHYLFQTFCSS 127

Query: 173 MHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTF 232
            HPM     AV  L        A+          +Y L  A+ +IA++P +AA  Y+ + 
Sbjct: 128 SHPMAIMLAAVGSLS-------AFYPDLLNCKEADYKLT-AIRMIAKIPTIAAMSYKYSI 179

Query: 233 HGGKHVPAEKIEKVDD-MGMRLARS-LGFELNEF--DELMRLYLVLHADHEGGNVSAHAV 288
                 P   ++  ++ + M  A     +++N    + L +++ +LHADHE  N S   V
Sbjct: 180 GQPFIYPDNSLDFTENFLHMMFAMPCTKYKVNPIIKNALNKIF-ILHADHEQ-NASTSTV 237

Query: 289 RLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWE 348
           R+ GS+ ++P+   + G+  L GP HG AN+ V    + M +++G    ++EN+ +   +
Sbjct: 238 RIAGSSGANPFACISTGIASLWGPAHGGANEAV----INMLKEIG----SSENIPKYIAK 289

Query: 349 TLREGHV--IPGFGHAVLRRTDPRYTAQREFA------LKHLPHDEMFQLVSKLYEVVPR 400
              +     + GFGH V +  DPR    +E        L  L ++ + Q+  +L  +  +
Sbjct: 290 AKDKNDPFRLIGFGHRVYKNYDPRAAVLKETCKEVLKELGQLENNPLLQIAIELEAIALK 349

Query: 401 VLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP- 459
             +E    +  +PNVD +SGI+ +  G + S  +TVLF ++R +G ++   W    G P 
Sbjct: 350 --DEYFIERKLYPNVDFYSGIIYKAMG-IPSQMFTVLFAIARTIGWMAQ--WKEMHGDPE 404

Query: 460 --IERPK 464
             I RP+
Sbjct: 405 QKISRPR 411


ref|ZP_00302992.1| COG0372: Citrate synthase [Novosphingobium aromaticivorans DSM 12444]
(421 aa)

Score: 97 bits (241), Expect: 7.90319e-19
Length: 379, Idn/Pos/Gap = 101/168/53 (26%/44%/13%)

Query: 113 LLPRAKPSGEQPLPEGLL---WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELP 169
           LL R  P G+       +   +LLL GE+P++ ++    + + R   +  ++        
Sbjct:  60 LLHRGYPIGQLAEHSSFMEVSYLLLNGELPSQQELADFTRTITRHTMLHEQLATFYRGFR 119

Query: 170 HERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYR 229
            +  HPM      V  L        A+   +   +   +    +  LIA++P +AA  Y+
Sbjct: 120 RD-AHPMAIMCGVVGALS-------AFYHDSTDISDPTHRKISSHRLIAKMPTIAAMAYK 171

Query: 230 NTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFD------ELMRLYLVLHADHEGGNV 283
            +       P  K+      G  L  + G    E++      + M    +LHADHE  N 
Sbjct: 172 YSVGQPFVYPDNKLSYT---GNFLKMTFGVPAEEYEVIPAVEKAMDRIFILHADHEQ-NA 227

Query: 284 SAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQM--KEKLGNRPMTTEN 341
           S   VRL GS+ ++P+   AAG+  L GP HG AN+  L  L ++   +K+   P   E 
Sbjct: 228 STSTVRLAGSSGANPFACIAAGIACLWGPAHGGANEAALNMLKEIGTPDKI---PHYIER 284

Query: 342 LRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREF------ALKHLPHDEMFQLVSKLY 395
            ++       +   + GFGH V +  DPR T  ++       ALK   +D +F+   +L 
Sbjct: 285 AKD-----KNDPFRLMGFGHRVYKNYDPRATVMQQTVREVFDALK--VNDPLFETALRLE 337

Query: 396 EVV---PRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVW 452
           E+    P  +E     K  +PNVD +SGI+L   G   +  +TVLF ++R +G ++   W
Sbjct: 338 EIALNDPYFVE-----KKLFPNVDFYSGIILSAIGF-PTTMFTVLFALARTVGWVAQ--W 389

Query: 453 DRALGLP---IERPKSVTT 468
           +  +  P   I RP+ + T
Sbjct: 390 NEMISDPGQKIGRPRQLYT 408


dbj|BAD93378.1| citrate synthase [Chlorobium limicola]
(447 aa)

Score: 97 bits (241), Expect: 8.73547e-19
Length: 386, Idn/Pos/Gap = 97/176/40 (25%/45%/10%)

Query:  90 ETSLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVC 148
           + + +D ++GI R+RG+ I +            E+       +LL+ GE+P + ++    
Sbjct:  63 QITFIDGEKGILRYRGYPIEQL----------AEKSSFLETAYLLIKGELPDKERLAVWT 112

Query: 149 QDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEY 208
            +++        + + +D   ++  HPM      V  L      A+  ++   +      
Sbjct: 113 YNIRHHTMTHANLTKFMDGFRYD-AHPMGILVGTVGALSTFYPDAKQVSEEESRKL---- 167

Query: 209 CLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDD---MGMRLARSLGFELNE-F 264
                  LI ++P +AA  +R++      +P   +    +   M  R+     +E N   
Sbjct: 168 ---QVRRLIGKIPTLAAMSFRHSLGFPYVLPDNDLSYAGNFLSMMFRMTEQ-KYEPNPVL 223

Query: 265 DELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRW 324
           ++ + +  +LHADHE  N S +AVR V S++ DPY + AAG   L GPLHG AN+ V+R 
Sbjct: 224 EKALDVLFILHADHEQ-NCSTNAVRSVSSSMVDPYSAIAAGCAALYGPLHGGANEAVIR- 281

Query: 325 LLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPH 384
           +L+    + N P   ++++        EG ++ GFGH V +  DPR    ++ A +    
Sbjct: 282 MLEGIGSVDNIPAFIKSVKS------GEGRLM-GFGHRVYKNYDPRARIIKKIAFEVFEE 334

Query: 385 DEMFQLVSKLYEVVPRVLEEQGKV-KNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRA 443
                L+    E+    LE+   V +  +PNVD +SG++ +  G   ++ + VLF + R 
Sbjct: 335 TGRNPLLDIAIELERIALEDDYFVGRKLYPNVDFYSGLIYQAMGF-PTDMFPVLFAIGRT 393

Query: 444 LGTLSSLVWDRALGLP---IERPKSV 466
            G L+   W   +  P   I RP+ +
Sbjct: 394 PGWLAQ--WIEHVKDPEQRIARPRQI 417


ref|NP_778970.1| citrate synthase [Xylella fastidiosa Temecula1]
gb|AAO28619.1| citrate synthase [Xylella fastidiosa Temecula1]
(429 aa)

Score: 97 bits (241), Expect: 9.03194e-19
Length: 346, Idn/Pos/Gap = 94/155/24 (27%/44%/6%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LL+ GE+P + +      ++     +   +   L    H   HPM   + +V+ L    
Sbjct:  89 YLLMNGELPRKDEFAKFDDEITHHTMMHESLKNFLGGF-HYDAHPMAMLAASVASLS--- 144

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDM- 249
               A+          E     A+ LIA++P +AA  +R +       P   +  V+   
Sbjct: 145 ----AFYHDTLDLNDLEQRRLAAIRLIAKVPTLAAAAHRYSIGWPIRYPRNNLGYVERFL 200

Query: 250 -GMRLARSLGFELNEF-DELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLN 307
             M    S   +LN    + + L  +LHADHE  N S   VRLVGS  ++PY S AAG+ 
Sbjct: 201 HMMFEVPSEPLQLNPVVIKALDLLFILHADHEQ-NASTSTVRLVGSTGANPYASVAAGIT 259

Query: 308 GLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRT 367
            L GP HG AN+ VL+    M E++G+       + +   +       + GFGH V +  
Sbjct: 260 ALWGPAHGGANEAVLK----MLEEIGDAKNVDLVIAKAKTKDKNSPFRLMGFGHRVYKHF 315

Query: 368 DPRYTAQREFALKHLP----HDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILL 423
           DPR    RE A   L     +D + ++  KL E   +  ++    +  +PNVD +SGI+ 
Sbjct: 316 DPRAKIIREMAHTVLGELGVNDPLLEVALKLEEAALK--DDYFVQRKLYPNVDFYSGIIY 373

Query: 424 RYYGLVESNFYTVLFGVSRALGTLSSLVWDRA-LGLPIERPKSVTT 468
           +    +    +TV+F ++R  G +S  +  +    + I RP+ + T
Sbjct: 374 KAIN-IPLEMFTVMFAIARTAGWVSHWLEQQVDPEMKISRPRQIYT 418


gb|AAO08700.1| Citrate synthase [Vibrio vulnificus CMCP6]
ref|NP_759173.1| Citrate synthase [Vibrio vulnificus CMCP6]
ref|NP_933820.1| citrate synthase [Vibrio vulnificus YJ016]
dbj|BAC93791.1| citrate synthase [Vibrio vulnificus YJ016]
(429 aa)

Score: 97 bits (241), Expect: 9.03194e-19
Length: 365, Idn/Pos/Gap = 99/159/48 (27%/43%/13%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           ++LL GE PT  Q E     + R   V  ++         +  HPM      V  L    
Sbjct:  88 YILLYGEAPTREQYEKFKTTVTRHTMVHEQIASFFHGFRRD-AHPMAVMCGVVGAL---- 142

Query: 191 KMAEAYAQGAPKSTFWEYCLE---------DALTLIARLPAVAARIYRNTFHGGKHVPAE 241
                       + F+   L+          A  L++++P +AA  Y+ +       P  
Sbjct: 143 ------------AAFYHDSLDINNDLHREITAYRLLSKMPTLAAMCYKYSTGQPFIYPRN 190

Query: 242 KIEKVDD-MGMRLARSLG-FELNEF-DELMRLYLVLHADHEGGNVSAHAVRLVGSALSDP 298
            +   ++ + M  A     +E+N      M     LHADHE  N S   VRL GS+ ++P
Sbjct: 191 DLSYAENFLHMMFATPCEEYEVNPVVARAMDKIFTLHADHEQ-NASTSTVRLAGSSGANP 249

Query: 299 YLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPG 358
           +   AAG+  L GP HG AN+  L+ L ++   + N P   +  ++       +   + G
Sbjct: 250 FACIAAGIASLWGPAHGGANEACLKMLEEIGS-VDNIPEYVDRAKD-----KDDPFRLMG 303

Query: 359 FGHAVLRRTDPRYTAQREF---ALKHLP-HDEMFQLVSKLYEVVPRVLEEQGKVKNPWPN 414
           FGH V +  DPR T  RE     LK L   D +  +  +L  +   + +E    K  +PN
Sbjct: 304 FGHRVYKNYDPRATVMRETCHEVLKELNIQDPLLDVAMELERIA--LSDEYFVSKKLYPN 361

Query: 415 VDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPKSVTTQWI 471
           VD +SGI+L+  G+  S F TV+F +SR +G ++   W+     P   I RP+ + T  +
Sbjct: 362 VDFYSGIILKAIGIPVSMF-TVIFAISRTIGWIAH--WNEMHSDPLNRIGRPRQLYTGEV 418

Query: 472 REHFE 476
           +  F+
Sbjct: 419 QRDFQ 423


sp|Q9RWB2|CISY_DEIRA Citrate synthase
(377 aa)

Score: 97 bits (240), Expect: 9.98308e-19
Length: 332, Idn/Pos/Gap = 89/152/24 (26%/45%/7%)

Query: 121 GEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFS 180
            E+   E L   LL  ++PT  ++     +LK   A+P +++ ++ ++P + +HPM    
Sbjct:  39 AEKSTFEELSLALLDAKLPTAEELAKFDAELKANRAIPDQLVGIIRDMP-KGVHPMQALR  97

Query: 181 VAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPA 240
            AVS L      AE     A ++         +  +IA+   + A I  N    G+ + A
Sbjct:  98 TAVSYLGLLDPQAEDITPEARRAI--------STRMIAQFSTIIAAI--NRAQEGQDIVA 147

Query: 241 EKIEKVDDMGMRLARSLGFELN-EFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPY 299
            + + +   G  L    G E   E   L  + LVLHADH G N S        S LSD Y
Sbjct: 148 PRAD-LTHAGNFLYMLTGNEPTPEQARLFDIALVLHADH-GMNASTFTAIATSSTLSDMY 205

Query: 300 LSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGF 359
               + +  L GPLHG AN+ V    + M +++G    T +         L     I G 
Sbjct: 206 SCMVSAIGALKGPLHGGANEAV----MTMLDEIG----TVDKAEAYITGKLDNKEKIMGV 257

Query: 360 GHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHS 419
           GH V +  DPR    R++A +H+ + E      ++ E + +++ ++   K  +PNVD +S
Sbjct: 258 GHRVYKYFDPRSRVLRDYA-EHVANKEGKSNYYQILEAIEKIIVDRMGAKGIYPNVDFYS 316

Query: 420 GILLRYYGLVESNFYTVLFGVSRALGTLSSLV 451
           G +    G ++  ++T +F ++R  G  +S++
Sbjct: 317 GTVYSDLG-IKKEYFTPIFALARISGWCASVI 347


ref|YP_208026.1| putative citrate synthase [Neisseria gonorrhoeae FA 1090]
gb|AAW89614.1| putative citrate synthase [Neisseria gonorrhoeae FA 1090]
(427 aa)

Score: 97 bits (240), Expect: 1.04956e-18
Length: 357, Idn/Pos/Gap = 102/165/49 (28%/46%/13%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LL+ GE+PT  Q       ++R   V  ++         +  HPM      V  L    
Sbjct:  88 YLLIYGELPTPEQKAEFDNTVRRHTMVHEQLTWFFRGFRRD-AHPMAMMVGVVGALS--- 143

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDD-M 249
               A+ Q +   T  E+       LI+++P +AA  YR +     + P   +   ++ +
Sbjct: 144 ----AFYQDSLDITNPEHRKIAIYRLISKIPTIAAMCYRYSNGLPFNYPKNNLSYSENFL 199

Query: 250 GMRLARSL-GFELNEF--DELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGL 306
            M  A     ++ N      L R++ +LHADHE  N S   VRL GS+ ++P+   AAG+
Sbjct: 200 HMMFATPCEDYKPNPVLARALDRIF-ILHADHEQ-NASTSTVRLAGSSGANPFACIAAGI 257

Query: 307 NGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRR 366
             L G  HG AN+ VL+ L ++ + + N     E +++  +  +       GFGH V R 
Sbjct: 258 ACLWGASHGGANEAVLKMLDEIGD-VSNVAAYMEGVKQRKYRLM-------GFGHRVYRN 309

Query: 367 TDPRYTAQREF---ALKHLPHDE--MFQLVSKLYEVVPRVLEEQGKVKNP-------WPN 414
            DPR +  RE     LK L  ++   F+L  +L         EQ  +K+P       +PN
Sbjct: 310 MDPRASIMRETCYEVLKELGLEDSPKFKLAMEL---------EQIALKDPFFIERKLYPN 360

Query: 415 VDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPKSVTT 468
           VD +SGI+L   G + +  +TV+F +SR++G +S   W   +  P   I RP+ + T
Sbjct: 361 VDFYSGIVLSALG-IPTEMFTVIFALSRSVGWISH--WHEMISDPSLKIGRPRQLYT 414


ref|YP_129256.1| putative citrate synthase [Photobacterium profundum SS9]
emb|CAG19454.1| putative citrate synthase [Photobacterium profundum SS9]
(456 aa)

Score: 97 bits (240), Expect: 1.10344e-18
Length: 371, Idn/Pos/Gap = 96/158/60 (25%/42%/16%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           ++LL GE+PT +Q E     + R   V  ++         +  HPM      V  L    
Sbjct: 115 YVLLYGEVPTRAQYEFFRTTVTRHTMVHEQIASFFHGFRRD-AHPMAVMCGVVGAL---- 169

Query: 191 KMAEAYAQGAPKSTFWEYCLE---------DALTLIARLPAVAARIYRNTFHGGKHVPAE 241
                       + F+   L+          A  L++++P +A+  Y+ +       P  
Sbjct: 170 ------------AAFYHDSLDINNDSHREITAFRLLSKMPTLASMCYKYSIGQPFIFPRN 217

Query: 242 KIEKVDDMGMRLARSLGFELNEFD------ELMRLYLVLHADHEGGNVSAHAVRLVGSAL 295
            ++  ++    L         E+D        M     LHADHE  N S   VRL GS+ 
Sbjct: 218 DLDYAENF---LHMMFATPCEEYDVSPVIARAMDKIFTLHADHEQ-NASTSTVRLAGSSG 273

Query: 296 SDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHV 355
           ++P+   AAG+  L GP HG AN+  L+    M E++G+     E +     +   +   
Sbjct: 274 ANPFACIAAGIASLWGPAHGGANEACLK----MLEEIGSVDKIAEYIERA--KDKDDPFR 327

Query: 356 IPGFGHAVLRRTDPRYTAQREFALKHLP----HDEMFQLVSKLYEVV---PRVLEEQGKV 408
           + GFGH V +  DPR T  RE   + L      D +  +  +L  +    P  ++     
Sbjct: 328 LMGFGHRVYKNYDPRATVMREACHEVLEELNIQDPLLDIAMELERIALSDPYFID----- 382

Query: 409 KNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPKS 465
           K  +PNVD +SG++L+  G+  S F TV+F +SR +G ++   W    G P   I RP+ 
Sbjct: 383 KKLYPNVDFYSGLILKAIGIPISMF-TVIFAMSRTVGWIAH--WSEMHGDPDNRIGRPRQ 439

Query: 466 VTTQWIREHFE 476
           + T  ++  F+
Sbjct: 440 LYTGKLQREFK 450


ref|NP_354399.1| hypothetical protein AGR_C_2572 [Agrobacterium tumefaciens str. C58]
ref|NP_532082.1| citrate synthase [Agrobacterium tumefaciens str. C58]
gb|AAL42398.1| citrate synthase [Agrobacterium tumefaciens str. C58]
gb|AAK87184.1| AGR_C_2572p [Agrobacterium tumefaciens str. C58]
pir||AH2747 citrate synthase [imported] - Agrobacterium tumefaciens  (strain C58, Dupont)
pir||G97528 citrate synthase [imported] - Agrobacterium tumefaciens  (strain C58, Cereon)
(429 aa)

Score: 97 bits (240), Expect: 1.22986e-18
Length: 434, Idn/Pos/Gap = 114/189/61 (26%/43%/14%)

Query:  60 VRE-RFGEEVLDACTVNQAYG------GMRSLKAMVYETSLLDPQEGIRF-RGFSIPECQ 111
           VRE   G  V+D  T+ +  G      G  S  +   + + +D  EG+   RGF I +  
Sbjct:  19 VREGTIGPSVVDIATLYKHTGSFTYDPGFTSTASCESKITYIDGDEGVLLHRGFPIEQL-  77

Query: 112 RLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHE 171
                     EQ       +LLL GE+PT +Q +     + R   V  ++ R       +
Sbjct:  78 ---------AEQGDFLETCYLLLYGELPTAAQKKDFDTRVTRHTMVHEQMSRFFTGYRRD 128

Query: 172 RMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNT 231
             HPM      V  L        A+   +   T     +  +L +IA++P +AA  Y+  
Sbjct: 129 -AHPMAVMCGTVGALS-------AFYHDSTDITDPHQRMVASLRMIAKMPTIAAMAYK-- 178

Query: 232 FHGGKHV--PAEKIEKVDDMGMRLARSLGFELNEFDEL----MRLYLVLHADHEGGNVSA 285
           +H G+    P   ++   +  + +  ++  E  + D +    M    +LHADHE  N S 
Sbjct: 179 YHIGQPFVYPKNDLDYASNF-LHMCFAVPCEDYKVDPVLARAMDRIFILHADHEQ-NAST 236

Query: 286 HAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLREL 345
             VRL GS+ ++P+   AAG+  L GP HG AN+      L M  ++G+     E +   
Sbjct: 237 STVRLAGSSGANPFACIAAGIACLWGPAHGGANEAA----LNMLNEIGSVDRIPEYIARA 292

Query: 346 CWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHL-----PHDEMFQLVSKLYEVV-- 398
             +   +   + GFGH V +  DPR    ++   + L       D + Q+  +L ++   
Sbjct: 293 --KDKNDPFRLMGFGHRVYKNYDPRAKIMQKTMYEVLEATGNSDDPIMQVALELEKIALS 350

Query: 399 -PRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALG 457
            P  +E     K  +PNVD +SGI L+  G   +  +TVLF ++R +G ++   W+  + 
Sbjct: 351 DPYFVE-----KKLYPNVDFYSGITLKALGF-PTTMFTVLFALARTVGWIAQ--WNEMIE 402

Query: 458 LP---IERPKSVTT 468
            P   I RP+ + T
Sbjct: 403 DPQQRIGRPRQLYT 416


gb|AAF95238.1| citrate synthase [Vibrio cholerae O1 biovar eltor str. N16961]
ref|NP_231724.1| citrate synthase [Vibrio cholerae O1 biovar eltor str. N16961]
pir||B82119 citrate synthase VC2092 [imported] - Vibrio cholerae (strain N16961 serogroup O1)
(431 aa)

Score: 97 bits (240), Expect: 1.22986e-18
Length: 351, Idn/Pos/Gap = 102/156/36 (29%/44%/10%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQ--- 187
           ++LL GE P   Q E   + + R   V  ++         +  HPM      V  L    
Sbjct:  90 YILLYGEAPNRKQYEEFKKIVTRHTMVHEQIASFFHGFRRD-AHPMAVMCGVVGALAAFY 148

Query: 188 HESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVD 247
           H+S             T  E     A  L++++P +AA  Y+ +       P   +   +
Sbjct: 149 HDS-------LDINNDTHREIA---AYRLLSKMPTLAAMCYKYSVGQPFIYPRNDLSYAE 198

Query: 248 D-MGMRLARSLG-FELNEF-DELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAA 304
           + + M  A     +E+N      M     LHADHE  N S   VRL GS+ ++P+   AA
Sbjct: 199 NFLHMMFATPCEEYEVNPIVARAMDKIFTLHADHEQ-NASTSTVRLAGSSGANPFACIAA 257

Query: 305 GLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVL 364
           G+  L GP HG AN+  LR    M E++G+     E +R    +   +   + GFGH V 
Sbjct: 258 GIASLWGPAHGGANEACLR----MLEEIGSVDKIPEYVRRA--KDKDDPFRLMGFGHRVY 311

Query: 365 RRTDPRYTAQREF---ALKHLP-HDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSG 420
           +  DPR T  RE     LK L   D +  +  +L  +   + +E    K  +PNVD +SG
Sbjct: 312 KNYDPRATVMREACHEVLKELSIQDPLLDVAMELERIA--LSDEYFIEKKLYPNVDFYSG 369

Query: 421 ILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPKSVTT 468
           I+L+  G+  S F TV+F +SR +G ++   W+     P   I RP+ + T
Sbjct: 370 IILKAIGIPVSMF-TVIFAMSRTIGWIAH--WNEMHSDPDNRIGRPRQLYT 417


ref|ZP_00170189.2| COG0372: Citrate synthase [Ralstonia eutropha JMP134]
(433 aa)

Score: 96 bits (239), Expect: 1.30383e-18
Length: 352, Idn/Pos/Gap = 99/167/41 (28%/47%/11%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPM---TQFSVAVSLLQ 187
           +LLL GE+P  +Q E     + +   V  ++   L     +  HPM   T    A+S   
Sbjct:  92 YLLLKGELPDATQKEEFVGRVMKHTMVHEQLQFFLRGFRRD-AHPMAVLTGLVGAMSAFY 150

Query: 188 HESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVD 247
           H++   +   Q              A+ LIA++P + A  Y+         P   +    
Sbjct: 151 HDAMDIDDPHQREIS----------AIRLIAKMPTLVAMAYKYNIGQPYIYPQNDLSYSG 200

Query: 248 D-MGMRLARSLG-FELNEFDE--LMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFA 303
           + + M  A     + +N   E  L R++ +LHADHE  N S   VRL GS+ ++P+ + A
Sbjct: 201 NFLRMMFATPCAPYTVNPVLERALDRIF-ILHADHEQ-NASTSTVRLAGSSGTNPFAAIA 258

Query: 304 AGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAV 363
           AG+  L GP HG AN+  L+    M E++G+     E ++++  +    G  + GFGH V
Sbjct: 259 AGVACLWGPAHGGANEAALK----MLEEIGSVDNIGEFIKQV--KDKNSGVRLMGFGHRV 312

Query: 364 LRRTDPRYTAQREFALK-----HLPHDEMFQLVSKLYEVVPRVLEEQGKV-KNPWPNVDQ 417
            +  DPR    RE   +      L +D +F+L  +L ++    LE++  V +  +PNVD 
Sbjct: 313 YKNYDPRAKLMRETCHEVLNELGLHNDPLFKLAMELEKI---ALEDEYFVSRKLYPNVDF 369

Query: 418 HSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPKSV 466
           +SGI+ R  G + ++ +T +F ++R  G +S   W+  +  P   I RP+ +
Sbjct: 370 YSGIVQRALG-IPTSLFTCIFALARTPGWISQ--WEEMITDPEYKIGRPRQL 418


emb|CAH12521.1| citrate synthase [Legionella pneumophila str. Paris]
ref|YP_123694.1| citrate synthase [Legionella pneumophila str. Paris]
(423 aa)

Score: 96 bits (239), Expect: 1.31476e-18
Length: 354, Idn/Pos/Gap = 95/161/42 (26%/45%/11%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMT---QFSVAVSLLQ 187
           +LLL GE+P + + ++    +     V  ++ + L+    +  HPM        A+S   
Sbjct:  88 YLLLNGELPNKEEKKAFVSLINNHTMVHQQMYQFLNGFRRD-AHPMAIMVGIVGALSAFY 146

Query: 188 HESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVD 247
           HES M    AQ    S         A+ L+A++P +AA  Y+ +       P  K+   +
Sbjct: 147 HES-MDLNNAQDRFIS---------AIRLVAKMPTLAAMSYKYSIGMPYMYPKNKMSYAE 196

Query: 248 DMGMRLARSLGFELNEFDEL----MRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFA 303
           +  + +   +  E    D +    M    +LHADHE  N S   VRL GS  ++P+   +
Sbjct: 197 NF-LHMMFGVPSEDTTPDPVLVRAMDTIFILHADHEQ-NASTSTVRLAGSTGANPFACIS 254

Query: 304 AGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAV 363
           AG+  L GP HG AN+      L M +++G+       ++    +   +   + GFGH V
Sbjct: 255 AGIGALWGPAHGGANEAC----LNMLKEIGDVSRIDHYIKRA--KDKNDPFRLMGFGHRV 308

Query: 364 LRRTDPRYTAQRE--------FALKHLPHDEMFQLVSKLYEVVPRVLEEQGKV-KNPWPN 414
            +  DPR    R+           K  P   +F+L  +L  +    LE++  + K  +PN
Sbjct: 309 YKSYDPRAKVMRKTCYDVLEAVGAKEAP---LFKLAMELERI---ALEDEYFIEKKLYPN 362

Query: 415 VDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLPIERPKSVTT 468
           VD +SG+ L   G + +N +TV+F ++R +G +S  +   A    I RP+ + T
Sbjct: 363 VDFYSGLTLSAIG-IPTNMFTVIFALARTVGWMSHWMEMVATKSRIGRPRQLYT 415


gb|EAA69037.1| hypothetical protein FG02352.1 [Gibberella zeae PH-1]
ref|XP_382528.1| hypothetical protein FG02352.1 [Gibberella zeae PH-1]
(496 aa)

Score: 96 bits (239), Expect: 1.34808e-18
Length: 375, Idn/Pos/Gap = 98/168/42 (26%/44%/11%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LL+ GE+PT+S+ +    ++     +  ++  +     ++  HPM+  + A + L   +
Sbjct: 106 YLLIYGELPTKSEYDLWHGEVMHHTYIHSDIENMFKSFRYDS-HPMSMLTAAFATLGAFA 164

Query: 191 KMAEAYAQGAPKST--------FWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEK 242
             A     G    T          +   +  L ++ + P +AA  YR       + PA+ 
Sbjct: 165 PEANPSLAGQKLYTNAASGNLEALQMLDKQILRILGKAPTLAAASYRMRQGRPFNRPAQD 224

Query: 243 IEKVDDMGMRLARSLGFELNEFDELMRLY---LVLHADHEGGNVSAHAVRLVGSALSDPY 299
           +    +    L      +      L R      ++HADHE  N S   V  VGS+L DPY
Sbjct: 225 LGYTGNFLYLLDHLSETDYKPHPVLARALDKLFIIHADHEV-NCSTATVMQVGSSLVDPY 283

Query: 300 LSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGF 359
              AAG   L GP HG A++  +R L+++         + EN+        +   V+ GF
Sbjct: 284 SVVAAGCAALYGPSHGGASESAIRMLIEIG--------SPENVPAFMQAVEKRERVLVGF 335

Query: 360 GHAVLRRTDPRYTAQREFALKHLPHDEMFQLV--SKLYEVVPRVLE-----EQGKVKNPW 412
           GH V +  DPR TA R+ A      +E+F++   +KL +    + +     E  + +N +
Sbjct: 336 GHRVYKNVDPRSTAIRKLA------EEVFEVTGRNKLLDTALTLADYARKSEFMRSRNLY 389

Query: 413 PNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRAL----GLPIERPKSV-T 467
           PNVD +SG++ +  G    +FY VLF V R +G L+   W + +    G+ I RP+ +  
Sbjct: 390 PNVDFYSGLIYQAMGF-PLDFYPVLFAVPRCVGWLAH--WRQMMLNSAGVKIWRPRQLYI 446

Query: 468 TQWIREHFEKRSVSA 482
            +  RE+ E +   A
Sbjct: 447 GEGEREYVEAKDRKA 461


ref|ZP_00236048.1| citrate synthase [Bacillus cereus G9241]
gb|EAL16116.1| citrate synthase [Bacillus cereus G9241]
(371 aa)

Score: 96 bits (239), Expect: 1.47766e-18
Length: 334, Idn/Pos/Gap = 91/153/42 (27%/45%/12%)

Query: 127 EGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLL 186
           E +++LL   ++P E ++    + +     VP E+L  L ++  +  HPM+    A+S+L
Sbjct:  42 EEVVYLLWHRKLPNEQELAEFNEIVSEYYKVPGEILAYLKQVDLKIAHPMSVLRTAISML 101

Query: 187 QHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKV 246
               + AE   +   KS + +     A   +  L A  ARI +           + +E  
Sbjct: 102 SLYDESAEIMDE---KSNYLKAVKLQAQ--VGTLVAAYARIRKGL---------DVVEPR 147

Query: 247 DDMGMRLARSLGFELNEFD------ELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYL 300
           +D+   LA +  + LN+ +      E     LVLHADHE  N S    R+  + LSD Y 
Sbjct: 148 NDLS--LAANFLYMLNDREPNEVEIEAFDKALVLHADHEL-NASTFTARVCVATLSDVYS 204

Query: 301 SFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFG 360
              A +  L GPLHG AN+ V++ L ++ E+        EN+       L+    I GFG
Sbjct: 205 GITAAIGALKGPLHGGANENVMKMLTEIGEE--------ENVESYIHNALQNKVKIMGFG 256

Query: 361 HAVLRRTDPRYTAQREFALK---HLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQ 417
           H V  + DPR    RE + +    L  ++ + +  K+ ++V        K K   PNVD 
Sbjct: 257 HRVYEQGDPRAKHLREMSKRLCVLLGEEKWYNMSIKIEDIVT-------KEKGLPPNVDF 309

Query: 418 HSGILLRYYGLVESNFYTVLFGVSRALGTLSSLV 451
           +S  +    G ++ + +T +F +SR  G L+ ++
Sbjct: 310 YSASVYHCLG-IDHDLFTPIFAISRMSGWLAHIL 342


ref|YP_085914.1| citrate synthase [Bacillus cereus ZK]
gb|AAU15934.1| citrate synthase [Bacillus cereus ZK]
ref|YP_038638.1| citrate synthase [Bacillus thuringiensis serovar konkukian str. 97-27]
gb|AAT60897.1| citrate synthase [Bacillus thuringiensis serovar konkukian str. 97-27]
(371 aa)

Score: 96 bits (239), Expect: 1.49005e-18
Length: 334, Idn/Pos/Gap = 91/153/42 (27%/45%/12%)

Query: 127 EGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLL 186
           E +++LL   ++P E ++    + +     VP E+L  L ++  +  HPM+    A+S+L
Sbjct:  42 EEVVYLLWHRKLPNEQELAKFNEIVSEYYKVPGEILAYLKQVDLKIAHPMSVLRTAISML 101

Query: 187 QHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKV 246
               + AE   +   KS + +     A   +  L A  ARI +           + +E  
Sbjct: 102 SLYDESAEIMDE---KSNYLKAVKLQAQ--VGTLVAAYARIRKGL---------DVVEPR 147

Query: 247 DDMGMRLARSLGFELNEFD------ELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYL 300
           +D+   LA +  + LN+ +      E     LVLHADHE  N S    R+  + LSD Y 
Sbjct: 148 NDLS--LAANFLYMLNDREPNEVEIEAFDKALVLHADHEL-NASTFTARVCVATLSDVYS 204

Query: 301 SFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFG 360
              A +  L GPLHG AN+ V++ L ++ E+        EN+       L+    I GFG
Sbjct: 205 GITAAIGALKGPLHGGANENVMKMLTEIGEE--------ENVESYIHNALQNKVKIMGFG 256

Query: 361 HAVLRRTDPRYTAQREFALK---HLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQ 417
           H V  + DPR    RE + +    L  ++ + +  K+ ++V        K K   PNVD 
Sbjct: 257 HRVYEQGDPRAKHLREMSKRLCVLLGEEKWYNMSIKIEDIVT-------KEKGLPPNVDF 309

Query: 418 HSGILLRYYGLVESNFYTVLFGVSRALGTLSSLV 451
           +S  +    G ++ + +T +F +SR  G L+ ++
Sbjct: 310 YSASVYHCLG-IDHDLFTPIFAISRMSGWLAHIL 342


ref|NP_465092.1| hypothetical protein lmo1567 [Listeria monocytogenes EGD-e]
emb|CAC99645.1| citZ [Listeria monocytogenes]
ref|ZP_00234317.1| citrate synthase [Listeria monocytogenes str. 1/2a F6854]
gb|EAL05864.1| citrate synthase [Listeria monocytogenes str. 1/2a F6854]
pir||AG1270 citrate synthase chain II homolog citZ [imported] - Listeria monocytogenes (strain EGD-e)
(373 aa)

Score: 96 bits (239), Expect: 1.52781e-18
Length: 328, Idn/Pos/Gap = 89/147/32 (27%/44%/9%)

Query: 127 EGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLL 186
           E +++LL    +P + + +   ++++   AV   ++  L    H+++HPM+     VS+L
Sbjct:  43 EEVIYLLWHLRLPNKDEFKKFKREIQENMAVSETIITSLRMQNHQKLHPMSVLRTTVSML 102

Query: 187 ---QHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKI 243
                E+++ +            E      L L A++P + A   R    G   +P    
Sbjct: 103 GVFDTEAELDDG-----------EAVYRKGLRLQAKMPTIVAAFSR-IRRGLDPIPPR-- 148

Query: 244 EKVDDMGMRLARSLGFELNEFD-ELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSF 302
           E ++     L    G E +E   E M   LVLHADHE  N S    R+  + LSD Y   
Sbjct: 149 EDLNMAANFLYMITGEEADELSVEAMNKALVLHADHEF-NASTFTARVCVATLSDVYSGV 207

Query: 303 AAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHA 362
            A +  L GPLHG AN+ V   L ++ +          ++R    E +     I GFGH 
Sbjct: 208 TAAIGALKGPLHGGANERVFDMLEEIDQ--------AGDVRNYIQEKIDTKQKIMGFGHR 259

Query: 363 VLRRTDPRYTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGIL 422
           V R  DPR    RE + K        +   K +++  +V E   ++K+  PNVD +S  +
Sbjct: 260 VYRGGDPRAQHLREMSRKLTAE----KGEEKWFDISLQVEESVWELKHLKPNVDFYSASV 315

Query: 423 LRYYGLVESNFYTVLFGVSRALGTLSSL 450
               G ++ + +T++F VSR  G L+ +
Sbjct: 316 YHALG-IDRDLFTLVFSVSRVSGWLAHI 342


gb|AAF10336.1| citrate synthase [Deinococcus radiodurans]
pir||A75479 citrate synthase - Deinococcus radiodurans (strain R1)
ref|NP_294481.1| citrate synthase [Deinococcus radiodurans R1]
(411 aa)

Score: 96 bits (239), Expect: 1.57967e-18
Length: 332, Idn/Pos/Gap = 89/152/24 (26%/45%/7%)

Query: 121 GEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFS 180
            E+   E L   LL  ++PT  ++     +LK   A+P +++ ++ ++P + +HPM    
Sbjct:  73 AEKSTFEELSLALLDAKLPTAEELAKFDAELKANRAIPDQLVGIIRDMP-KGVHPMQALR 131

Query: 181 VAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPA 240
            AVS L      AE     A ++         +  +IA+   + A I  N    G+ + A
Sbjct: 132 TAVSYLGLLDPQAEDITPEARRAI--------STRMIAQFSTIIAAI--NRAQEGQDIVA 181

Query: 241 EKIEKVDDMGMRLARSLGFELN-EFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPY 299
            + + +   G  L    G E   E   L  + LVLHADH G N S        S LSD Y
Sbjct: 182 PRAD-LTHAGNFLYMLTGNEPTPEQARLFDIALVLHADH-GMNASTFTAIATSSTLSDMY 239

Query: 300 LSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGF 359
               + +  L GPLHG AN+ V    + M +++G    T +         L     I G 
Sbjct: 240 SCMVSAIGALKGPLHGGANEAV----MTMLDEIG----TVDKAEAYITGKLDNKEKIMGV 291

Query: 360 GHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHS 419
           GH V +  DPR    R++A +H+ + E      ++ E + +++ ++   K  +PNVD +S
Sbjct: 292 GHRVYKYFDPRSRVLRDYA-EHVANKEGKSNYYQILEAIEKIIVDRMGAKGIYPNVDFYS 350

Query: 420 GILLRYYGLVESNFYTVLFGVSRALGTLSSLV 451
           G +    G ++  ++T +F ++R  G  +S++
Sbjct: 351 GTVYSDLG-IKKEYFTPIFALARISGWCASVI 381


ref|YP_021483.1| citrate synthase citz [Bacillus anthracis str. 'Ames Ancestor']
ref|NP_847042.1| citrate synthase CitZ [Bacillus anthracis str. Ames]
ref|YP_030736.1| citrate synthase CitZ [Bacillus anthracis str. Sterne]
ref|NP_658622.1| citrate_synt, Citrate synthase [Bacillus anthracis str. A2012]
gb|AAP28528.1| citrate synthase CitZ [Bacillus anthracis str. Ames]
gb|AAT33958.1| citrate synthase CitZ [Bacillus anthracis str. 'Ames Ancestor']
gb|AAT56786.1| citrate synthase CitZ [Bacillus anthracis str. Sterne]
(371 aa)

Score: 96 bits (239), Expect: 1.57967e-18
Length: 334, Idn/Pos/Gap = 91/153/42 (27%/45%/12%)

Query: 127 EGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLL 186
           E +++LL   ++P E ++    + +     VP E+L  L ++  +  HPM+    A+S+L
Sbjct:  42 EEVVYLLWHRKLPNEQELAKFNEIVSEYYKVPGEILAYLKQVDLKIAHPMSVLRTAISML 101

Query: 187 QHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKV 246
               + AE   +   KS + +     A   +  L A  ARI +           + +E  
Sbjct: 102 SLYDESAEIMDE---KSNYLKAVKLQAQ--VGTLVAAYARIRKGL---------DVVEPR 147

Query: 247 DDMGMRLARSLGFELNEFD------ELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYL 300
           +D+   LA +  + LN+ +      E     LVLHADHE  N S    R+  + LSD Y 
Sbjct: 148 NDLS--LAANFLYMLNDREPNEVEIEAFDKALVLHADHEL-NASTFTARVCVATLSDVYS 204

Query: 301 SFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFG 360
              A +  L GPLHG AN+ V++ L ++ E+        EN+       L+    I GFG
Sbjct: 205 GITAAIGALKGPLHGGANENVMKMLTEIGEE--------ENVESYIHNALQNKVKIMGFG 256

Query: 361 HAVLRRTDPRYTAQREFALK---HLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQ 417
           H V  + DPR    RE + +    L  ++ + +  K+ ++V        K K   PNVD 
Sbjct: 257 HRVYEQGDPRAKHLREMSKRLCVLLGEEKWYNMSIKIEDIVT-------KEKGLPPNVDF 309

Query: 418 HSGILLRYYGLVESNFYTVLFGVSRALGTLSSLV 451
           +S  +    G ++ + +T +F +SR  G L+ ++
Sbjct: 310 YSASVYHCLG-IDHDLFTPIFAISRMSGWLAHIL 342


ref|NP_948248.1| citrate synthase [Rhodopseudomonas palustris CGA009]
emb|CAE28348.1| citrate synthase [Rhodopseudomonas palustris CGA009]
(434 aa)

Score: 96 bits (239), Expect: 1.57967e-18
Length: 360, Idn/Pos/Gap = 97/161/53 (26%/44%/14%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQ--- 187
           +LLL GE+PT++Q E     + R   V  ++ R       +  HPM     +V  L    
Sbjct:  92 YLLLYGELPTKAQKEDFDYRVTRHNMVHEQMARFFQGFRRD-AHPMAVMVASVGALAAFY 150

Query: 188 HESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVD 247
           H+S       Q    S          + +IA++P +AA  Y+ +       P   +    
Sbjct: 151 HDSTDINDPTQRMVAS----------IRMIAKVPTLAAMAYKYSVGQPFIYPKNTLSYAA 200

Query: 248 DMGMRLARSLGFE--------LNEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPY 299
           +  +R+  +   E         N  D++      LHADHE  N S   VR+ GS+ ++P+
Sbjct: 201 NF-LRMCFATPCEEYVVNPVLANALDKI----FTLHADHEQ-NASTSTVRIAGSSGANPF 254

Query: 300 LSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIP-- 357
              AAG+  L GP HG AN+      L M +++G    T EN+ +   +   +   +   
Sbjct: 255 ACIAAGIACLWGPAHGGANEAA----LAMLKEIG----TVENIPDFIAKVKDKSSSVRLM 306

Query: 358 GFGHAVLRRTDPRYTAQREFALKHLPH-----DEMFQLVSKLYEVVPRVLEEQGKV-KNP 411
           GFGH V +  DPR    ++   + L       D + ++  +L ++    L +Q  + +  
Sbjct: 307 GFGHRVYKNYDPRAKIMQQVCHEVLAETGHHGDPLLKVAMELEKI---ALSDQYFIDRKL 363

Query: 412 WPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPKSVTT 468
           +PNVD +SGI L+  G   ++ +TVLF V+R +G +S   W   +  P   I RP+ + T
Sbjct: 364 YPNVDFYSGITLKAMGF-PTDMFTVLFAVARTVGWISQ--WSEMIEDPQQKIGRPRQLFT 420


ref|YP_095444.1| citrate synthase [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
emb|CAH15606.1| citrate synthase [Legionella pneumophila str. Lens]
ref|YP_126716.1| citrate synthase [Legionella pneumophila str. Lens]
gb|AAU27497.1| citrate synthase [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
(423 aa)

Score: 96 bits (239), Expect: 1.5929e-18
Length: 354, Idn/Pos/Gap = 95/161/42 (26%/45%/11%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMT---QFSVAVSLLQ 187
           +LLL GE+P + + ++    +     V  ++ + L+    +  HPM        A+S   
Sbjct:  88 YLLLNGELPNKEEKKAFVSLINNHTMVHQQMYQFLNGFRRD-AHPMAIMVGIVGALSAFY 146

Query: 188 HESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVD 247
           HES M    AQ    S         A+ L+A++P +AA  Y+ +       P  K+   +
Sbjct: 147 HES-MDLNNAQDRFIS---------AIRLVAKMPTLAAMSYKYSIGMPYMYPKNKMSYAE 196

Query: 248 DMGMRLARSLGFELNEFDEL----MRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFA 303
           +  + +   +  E    D +    M    +LHADHE  N S   VRL GS  ++P+   +
Sbjct: 197 NF-LHMMFGVPSEDTTPDPVLVRAMDTIFILHADHEQ-NASTSTVRLAGSTGANPFACIS 254

Query: 304 AGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAV 363
           AG+  L GP HG AN+      L M +++G+       ++    +   +   + GFGH V
Sbjct: 255 AGIGALWGPAHGGANEAC----LNMLKEIGDVSRIDHYIKRA--KDKNDPFRLMGFGHRV 308

Query: 364 LRRTDPRYTAQRE--------FALKHLPHDEMFQLVSKLYEVVPRVLEEQGKV-KNPWPN 414
            +  DPR    R+           K  P   +F+L  +L  +    LE++  + K  +PN
Sbjct: 309 YKSYDPRAKVMRKTCYDVLEAVGAKDAP---LFKLAMELERI---ALEDEYFIEKKLYPN 362

Query: 415 VDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLPIERPKSVTT 468
           VD +SG+ L   G + +N +TV+F ++R +G +S  +   A    I RP+ + T
Sbjct: 363 VDFYSGLTLSAIG-IPTNMFTVIFALARTVGWMSHWMEMVATKSRIGRPRQLYT 415


ref|NP_797221.1| citrate synthase [Vibrio parahaemolyticus RIMD 2210633]
dbj|BAC59105.1| citrate synthase [Vibrio parahaemolyticus RIMD 2210633]
(429 aa)

Score: 96 bits (238), Expect: 1.88218e-18
Length: 339, Idn/Pos/Gap = 95/151/27 (28%/44%/7%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           ++LL GE PT  Q E     + R   V  ++         +  HPM      V  L    
Sbjct:  88 YILLYGEAPTREQYEQFKTTVTRHTMVHEQIASFFHGFRRD-AHPMAVMCGVVGALA--- 143

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDD-M 249
               A+   +      E+    A  L++++P +AA  ++ +       P   +   ++ +
Sbjct: 144 ----AFYHDSLDINNDEHREIAAYRLLSKMPTLAAMCFKYSVGQPFIYPRNDLSYAENFL 199

Query: 250 GMRLARSLG-FELNEF-DELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLN 307
            M  A     +E+N      M     LHADHE  N S   VRL GS+ ++P+   AAG+ 
Sbjct: 200 HMMFANPCEEYEVNPVVARAMDKIFTLHADHEQ-NASTSTVRLAGSSGANPFACIAAGIA 258

Query: 308 GLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRT 367
            L GP HG AN+  L+ L ++   + N P   E  ++       +   + GFGH V +  
Sbjct: 259 SLWGPAHGGANEACLKMLEEIGS-VDNIPEYVERAKD-----KDDPFRLMGFGHRVYKNY 312

Query: 368 DPRYTAQREF---ALKHLP-HDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILL 423
           DPR T  RE     LK L   D +  +  +L  +   + +E    K  +PNVD +SGI+L
Sbjct: 313 DPRATVMRETCHEVLKELNIKDPLLDVAMELERIA--LSDEYFVSKKLYPNVDFYSGIIL 370

Query: 424 RYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLPIER 462
           +  G+  S F TV+F +SR +G ++   W+     P+ R
Sbjct: 371 KAIGIPVSMF-TVIFAISRTIGWIAH--WNEMHSDPLNR 406


gb|AAB02957.1| citrate synthase [Rickettsia canadensis]
sp|P51041|CISY_RICCA Citrate synthase
(411 aa)

Score: 96 bits (238), Expect: 1.92989e-18
Length: 451, Idn/Pos/Gap = 111/202/72 (24%/44%/15%)

Query:  44 EAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYG------GMRSLKAMVYETSLLDPQ  97
           E V  KI     ++  ++   GE+V+D   V+          G  S  +     + +D  
Sbjct:   3 EFVELKIRGKIFKLPILKASIGEDVIDISRVSSEADCFTYDPGFMSTASCRSTITYIDGD  62

Query:  98 EGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAA 156
           +GI R+RG+ I +          + +    E + +LL+ GE+P+  Q      +  ++ A
Sbjct:  63 KGILRYRGYDIKDL---------ADKSDFLE-VAYLLIYGELPSSEQY----NNFTKKVA 108

Query: 157 VPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLE----- 211
           V          L +ER+H + Q     +       MA   A     S F+   L      
Sbjct: 109 V--------HSLVNERLHYLFQ-----TFCSSSHPMAIMLAAVGSLSAFYPDLLNFKEAD 155

Query: 212 ---DALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDD-MGMRLARS-LGFELNEF-- 264
               A+ +IA++P +AA  Y+ +       P   ++  ++ + M  A   + +E+N    
Sbjct: 156 YELTAIRMIAKIPTMAAMSYKYSIGQPFIYPDNSLDFTENFLHMMFATPCMKYEVNPVIK 215

Query: 265 DELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRW 324
           + L +++ +LHADHE  N S   VR+ GS+ ++P+   + G+  L GP HG AN+ V   
Sbjct: 216 NALNKIF-ILHADHEQ-NASTSTVRIAGSSGANPFACISTGIASLWGPAHGGANEAV--- 270

Query: 325 LLQMKEKLGNRPMTTENLRELCWETLREGHV--IPGFGHAVLRRTDPRYTAQREFA---- 378
            + M +++G    ++EN+ +   +   +     + GFGH V +  DPR    +E      
Sbjct: 271 -INMLKEIG----SSENIPKYIAKAKDKDDPFRLMGFGHRVYKNYDPRAAVLKETCNEVL 325

Query: 379 --LKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTV 436
             L  L ++ + Q+  +L  +  +  +E    +  +PNVD +SGI+ +  G + S  +TV
Sbjct: 326 KELGQLENNPLLQIAIELEAIALK--DEYFIERKLYPNVDFYSGIIYKAMG-IPSQMFTV 382

Query: 437 LFGVSRALGTLSSLVWDRALGLP---IERPK 464
           LF ++R +G ++   W      P   I RP+
Sbjct: 383 LFAIARTVGWMAQ--WKEMHEDPEQKISRPR 411


ref|ZP_00376473.1| citrate synthase [Erythrobacter litoralis HTCC2594]
gb|EAL75203.1| citrate synthase [Erythrobacter litoralis HTCC2594]
(427 aa)

Score: 96 bits (238), Expect: 1.99539e-18
Length: 444, Idn/Pos/Gap = 114/186/57 (25%/41%/12%)

Query:  48 SKIEPMRAQVHEVRERFGEEVLDACTVNQAYG---------GMRSLKAMVYETSLLDPQE  98
           +K+E +  Q HE     G    D   + + YG         G +S  +     + +D  E
Sbjct:   5 AKLE-LNGQSHEFPVLQGTTGPDVVDIRKLYGATGAFTFDPGYKSTASCESALTYIDGNE  63

Query:  99 GIRFRGFSIPECQRLLPRAKPSG---EQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRA 155
           G+            LL R  P G   EQ     + +LLL GE+P + +++     + R  
Sbjct:  64 GV------------LLHRGYPIGQLAEQSSFMEVSYLLLNGELPKQDELDDFTYTITRHT 111

Query: 156 AVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALT 215
            +  + LR   +      HPM      V  L        A+   +   +  E+    +  
Sbjct: 112 MLHDQ-LRQFYQGFRRDAHPMAIMCGVVGALS-------AFYHDSTDISDPEHRKISSHR 163

Query: 216 LIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEF----DELMRLY 271
           LIA++P +AA  Y+         P   +    +  +R+   +  E  E     +  M   
Sbjct: 164 LIAKMPTIAAMAYKYAVGQPFLQPKNDLSYTGNF-LRMTFGVPAEDYEIHPAIERAMDRI 222

Query: 272 LVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEK 331
            +LHADHE  N S   VRL GS+ ++P+   AAG+  L GP HG AN+  L  +LQ    
Sbjct: 223 FILHADHEQ-NASTSTVRLAGSSGANPFACIAAGIACLWGPAHGGANEAALN-MLQEIGS 280

Query: 332 LGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQ----REFALKHLPHDEM 387
               P   E  ++       +   + GFGH V +  DPR T      RE        D +
Sbjct: 281 PDRIPHYIERAKD-----KNDPFRLMGFGHRVYKNYDPRATVMQQTLREVFEALNVQDPV 335

Query: 388 FQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTL 447
           F++  +L E+   + ++  + K  +PNVD +SGI+L   G   +  +T LF ++R +G +
Sbjct: 336 FEVALQLEEIA--LNDDYFREKKLFPNVDFYSGIILNAIGF-PTTMFTALFALARTVGWV 392

Query: 448 SSLVWDRALGLP---IERPKSVTT 468
           +   W+  +  P   I RP+ + T
Sbjct: 393 AQ--WNEMISDPGQVIGRPRQLYT 414


ref|NP_885393.1| citrate synthase [Bordetella parapertussis 12822]
emb|CAE35650.1| citrate synthase [Bordetella bronchiseptica RB50]
emb|CAE38510.1| citrate synthase [Bordetella parapertussis]
ref|NP_890212.1| citrate synthase [Bordetella bronchiseptica RB50]
(436 aa)

Score: 96 bits (238), Expect: 2.01211e-18
Length: 353, Idn/Pos/Gap = 95/165/32 (26%/46%/9%)

Query: 129 LLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQH 188
           + +L+L GE+P   Q +     +     V  ++   L     +  HPM   +  V  L  
Sbjct:  90 ICYLILNGELPNGGQKQDFDSQVTHHTMVNEQLHFFLRGFRRD-AHPMAVLTGLVGALS- 147

Query: 189 ESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDD 248
                 A+   +   T   +    A+ LIA++P + A  Y+ +       P   +    +
Sbjct: 148 ------AFYHDSTDITNPHHRHVSAIRLIAKMPTLVAMAYKYSQGQPFIYPQNDLSYTGN 201

Query: 249 -MGMRLARSLG-FELNEFDE--LMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAA 304
            + M  A     +++N+  E  L R++ +LHADHE  N S   VRL GS+ ++P+ + AA
Sbjct: 202 FLRMMFATPCEEYKVNDVVERALDRIF-ILHADHEQ-NASTSTVRLCGSSGTNPFAAIAA 259

Query: 305 GLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVL 364
           G+  L GP HG AN+  L+ L +++   G      E + ++  +    G  + GFGH V 
Sbjct: 260 GVACLWGPAHGGANEACLQMLEELQAN-GGVAKVGEFMEKV--KDKNSGVRLMGFGHRVY 316

Query: 365 RRTDPRYTAQRE-----FALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNP-WPNVDQH 418
           +  DPR    +E          L +D +F+L  +L  +    LE+   V+   +PNVD +
Sbjct: 317 KNYDPRAKLMQETCKEVLVALGLENDPLFKLAMELERI---ALEDDYFVQRKLYPNVDFY 373

Query: 419 SGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPKSVTT 468
           SGI+ R  G + ++ +T +F ++R +G ++   W+  L  P   I RP+ + T
Sbjct: 374 SGIVQRAIG-IPTSLFTAIFALARTVGWIAQ--WNEMLSDPDYKIGRPRQLFT 423


ref|YP_144609.1| citrate synthase [Thermus thermophilus HB8]
dbj|BAD71166.1| citrate synthase [Thermus thermophilus HB8]
pdb|1IXE|D Chain D, Crystal Structure Of Citrate Synthase From Thermus Thermophilus Hb8
pdb|1IXE|C Chain C, Crystal Structure Of Citrate Synthase From Thermus Thermophilus Hb8
pdb|1IXE|B Chain B, Crystal Structure Of Citrate Synthase From Thermus Thermophilus Hb8
pdb|1IXE|A Chain A, Crystal Structure Of Citrate Synthase From Thermus Thermophilus Hb8
pdb|1IOM|A Chain A, Crystal Structure Of Citrate Synthase From Thermus Thermophilus Hb8
(377 aa)

Score: 95 bits (237), Expect: 2.13313e-18
Length: 342, Idn/Pos/Gap = 106/149/32 (30%/43%/9%)

Query: 127 EGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLL 186
           E   +LLL G +P   ++E     L RR A+P  +L      P    HPM+    AVS  
Sbjct:  44 EETTFLLLHGRLPRRQELEEFSAALARRRALPAHLLESFKRYP-VSAHPMSFLRTAVS-- 100

Query: 187 QHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKV 246
             E  M +       +   +E      L LIA+   + A   R     GK  P    E +
Sbjct: 101 --EFGMLDPTEGDISREALYE----KGLDLIAKFATIVAANKR--LKEGKE-PIPPREDL 151

Query: 247 DDMGMRLARSLGFELN-EFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAG 305
                 L  + G E + E   LM   L+LHA+H G N S        S  +D Y +  A 
Sbjct: 152 SHAANFLYMANGVEPSPEQARLMDAALILHAEH-GFNASTFTAIAAFSTETDLYSAITAA 210

Query: 306 LNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLR 365
           +  L GP HG AN+ V+R    M +++G    T E  RE   E L +   I G GH V +
Sbjct: 211 VASLKGPRHGGANEAVMR----MIQEIG----TPERAREWVREKLAKKERIMGMGHRVYK 262

Query: 366 RTDPRYTAQREFA-LKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNP---WPNVDQHSGI 421
             DPR     + A L    H       SK Y+++  V EE GKV NP   +PNVD +SG+
Sbjct: 263 AFDPRAGVLEKLARLVAEKHGH-----SKEYQILKIVEEEAGKVLNPRGIYPNVDFYSGV 317

Query: 422 LLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLPIERP 463
           +    G     F+T +F V+R  G +  ++  + L   + RP
Sbjct: 318 VYSDLGF-SLEFFTPIFAVARISGWVGHILEYQELDNRLLRP 358


dbj|BAA96812.1| citrate synthase [Thermus thermophilus]
(377 aa)

Score: 95 bits (237), Expect: 2.16902e-18
Length: 342, Idn/Pos/Gap = 106/149/32 (30%/43%/9%)

Query: 127 EGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLL 186
           E   +LLL G +P   ++E     L RR A+P  +L      P    HPM+    AVS  
Sbjct:  44 EETTFLLLHGRLPRRQELEEFSAALARRRAMPAHLLESFKRYP-VSAHPMSFLRTAVS-- 100

Query: 187 QHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKV 246
             E  M +       +   +E      L LIA+   + A   R     GK  P    E +
Sbjct: 101 --EFGMLDPTEGDISREALYE----KGLDLIAKFATIVAANKR--LKEGKE-PIPPREDL 151

Query: 247 DDMGMRLARSLGFELN-EFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAG 305
                 L  + G E + E   LM   L+LHA+H G N S        S  +D Y +  A 
Sbjct: 152 SHAANFLYMANGVEPSPEQARLMDAALILHAEH-GFNASTFTAIAAFSTETDLYSAITAA 210

Query: 306 LNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLR 365
           +  L GP HG AN+ V+R    M +++G    T E  RE   E L +   I G GH V +
Sbjct: 211 VASLKGPRHGGANEAVMR----MIQEIG----TPERAREWVREKLAKKERIMGMGHRVYK 262

Query: 366 RTDPRYTAQREFA-LKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNP---WPNVDQHSGI 421
             DPR     + A L    H       SK Y+++  V EE GKV NP   +PNVD +SG+
Sbjct: 263 AFDPRAGVLEKLARLVAEKHGH-----SKEYQILKIVEEEAGKVLNPRGIYPNVDFYSGV 317

Query: 422 LLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLPIERP 463
           +    G     F+T +F V+R  G +  ++  + L   + RP
Sbjct: 318 VYSDLGF-SLEFFTPIFAVARISGWVGHILEYQELDNRLLRP 358


ref|YP_004947.1| citrate synthase [Thermus thermophilus HB27]
gb|AAS81320.1| citrate synthase [Thermus thermophilus HB27]
(377 aa)

Score: 95 bits (237), Expect: 2.31874e-18
Length: 342, Idn/Pos/Gap = 106/149/32 (30%/43%/9%)

Query: 127 EGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLL 186
           E   +LLL G +P   ++E     L RR A+P  +L      P    HPM+    AVS  
Sbjct:  44 EETTFLLLHGRLPRRQELEEFSAALARRRALPAHLLESFKRYP-VSAHPMSFLRTAVS-- 100

Query: 187 QHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKV 246
             E  M +       +   +E      L LIA+   + A   R     GK  P    E +
Sbjct: 101 --ELGMLDPTEGDISREALYE----KGLDLIAKFATIVAANKR--LKEGKE-PIPPREDL 151

Query: 247 DDMGMRLARSLGFELN-EFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAG 305
                 L  + G E + E   LM   L+LHA+H G N S        S  +D Y +  A 
Sbjct: 152 SHAANFLYMANGVEPSPEQARLMDAALILHAEH-GFNASTFTAIAAFSTETDLYSAITAA 210

Query: 306 LNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLR 365
           +  L GP HG AN+ V+R    M +++G    T E  RE   E L +   I G GH V +
Sbjct: 211 VASLKGPRHGGANEAVMR----MIQEIG----TPERAREWVREKLAKKERIMGMGHRVYK 262

Query: 366 RTDPRYTAQREFA-LKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNP---WPNVDQHSGI 421
             DPR     + A L    H       SK Y+++  V EE GKV NP   +PNVD +SG+
Sbjct: 263 AFDPRAGVLEKLARLVAEKHGH-----SKEYQILKIVEEEAGKVLNPRGIYPNVDFYSGV 317

Query: 422 LLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLPIERP 463
           +    G     F+T +F V+R  G +  ++  + L   + RP
Sbjct: 318 VYSDLGF-SLEFFTPIFAVARISGWVGHILEYQELDNRLLRP 358


gb|AAB09594.1| citrate synthase [Sulfolobus solfataricus]
(377 aa)

Score: 95 bits (237), Expect: 2.33817e-18
Length: 383, Idn/Pos/Gap = 97/170/53 (25%/44%/13%)

Query:  80 GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEI 138
           G+ ++   V   + +D ++GI R+RG++I +                 E  ++L+L G++
Sbjct:   7 GLENVIIKVTNLTFIDGEKGILRYRGYNIEDLVNYGSY----------EETIYLMLYGKL  56

Query: 139 PTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQ 198
            T+ ++  +   L     VP EVL  +  +P E        + A+ LL+    +  A   
Sbjct:  57 RTKKELNDLKAKLNEEYEVPQEVLDTIYLMPKE--------ADAIGLLE----VGTAALA 104

Query: 199 GAPKSTFW-EYCLEDALTLIARLPAVAARIYRNTFHGGKHVP--AEKIEKVDDMGMRLAR 255
              K+  W E   E A+++IA++  + A +YR        +P  ++   K   +      
Sbjct: 105 SIDKNFKWKENDKEKAISIIAKMATLVANVYRRKEGNKPRIPEPSDSFAKSFLLASFARE 164

Query: 256 SLGFELNEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHG 315
               E+N  D+     L+L+ DHE    S  A  +  S LSD Y S  A L  L GPLHG
Sbjct: 165 PTTDEINAMDKA----LILYTDHEV-PASTTAALVAASTLSDMYSSLTAALAALKGPLHG 219

Query: 316 LANQEVLRWLLQMKEKLGNRPMTTENLRELCW---ETLREGHVIPGFGHAVLRRTDPRYT 372
            A +E  +  +++ +     P   +N     W   + + + + + GFGH V +  DPR  
Sbjct: 220 GAAEEAFKQFIEIGD-----PNRVQN-----WFNDKVVNQKNRLMGFGHRVYKTYDPRAK 269

Query: 373 AQREFALKHLPHD----EMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGL 428
             ++ AL  +  +      F++  KL E+  +    +G     +PN D +SGI+    G 
Sbjct: 270 IFKKLALTLIERNADARRYFEIAQKLEELGIKQFSSKGI----YPNTDFYSGIVFYALGF 325

Query: 429 VESNFYTVLFGVSRALGTLSSLV 451
                +T LF +SR LG L+ ++
Sbjct: 326 -PVYMFTALFALSRTLGWLAHII 347


gb|AAM49623.1| citrate synthase [Rickettsia sp. IM1]
gb|AAM49622.1| citrate synthase [Rickettsia sp. IP1]
gb|AAB02959.1| citrate synthase [Rickettsia helvetica]
sp|Q59741|CISY_RICHE Citrate synthase
(411 aa)

Score: 95 bits (237), Expect: 2.39744e-18
Length: 427, Idn/Pos/Gap = 107/193/56 (25%/45%/13%)

Query:  60 VRERFGEEVLDACTVNQAYG------GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQR 112
           ++   GE+V++   V+          G  S  +     + +D  +GI R RG+ I     
Sbjct:  19 LKASIGEDVINISRVSAEADCFTYDPGFMSTASCQSTITYIDGDKGILRHRGYDI-----  73

Query: 113 LLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHER 172
                K   E+     + +LL+ GE+P+  Q  +  + +   + V  E L  L +     
Sbjct:  74 -----KDLAEKSDFLEVAYLLIYGELPSSEQYNNFTKQVAHHSLVN-ERLHYLFQTFCSS 127

Query: 173 MHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTF 232
            HPM     AV  L        A+          +Y L  A+ +IA++P +AA  Y+ + 
Sbjct: 128 SHPMAIMLAAVGSLS-------AFYPDLLNCKEADYKLT-AIRMIAKIPTIAAMSYKYSI 179

Query: 233 HGGKHVPAEKIEKVDD-MGMRLARS-LGFELNEF--DELMRLYLVLHADHEGGNVSAHAV 288
                 P   ++  ++ + M  A     +++N    + L +++ +LHADHE  N S   V
Sbjct: 180 GQPFIYPDNSLDFTENFLHMMFATPCTKYKVNPIIKNALNKIF-ILHADHEQ-NASTSTV 237

Query: 289 RLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWE 348
           R+ GS+ ++P+   + G+  L GP HG AN+ V    + M +++G    ++EN+ +   +
Sbjct: 238 RIAGSSGANPFACISTGIASLWGPAHGGANEAV----INMLKEIG----SSENIPKYIAK 289

Query: 349 TLREGHV--IPGFGHAVLRRTDPRYTAQREFA------LKHLPHDEMFQLVSKLYEVVPR 400
              +     + GFGH V +  DPR    +E        L  L ++ + Q+  +L  +  +
Sbjct: 290 AKDKNDPFRLIGFGHRVYKNYDPRAAVLKETCKEVLKELGQLENNPLLQIAIELEAIALK 349

Query: 401 VLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP- 459
             +E    +  +PNVD +SGI+ +  G + S  +TVLF ++R +G ++   W    G P 
Sbjct: 350 --DEYFIERKLYPNVDFYSGIIYKAMG-IPSQMFTVLFAIARTIGWMAQ--WKEMHGDPE 404

Query: 460 --IERPK 464
             I RP+
Sbjct: 405 QKISRPR 411


gb|AAP99231.1| Citrate synthase [Prochlorococcus marinus subsp. marinus str. CCMP1375]
ref|NP_874579.1| Citrate synthase [Prochlorococcus marinus subsp. marinus str. CCMP1375]
(392 aa)

Score: 95 bits (237), Expect: 2.45821e-18
Length: 380, Idn/Pos/Gap = 108/170/55 (28%/44%/14%)

Query: 100 IRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPP 159
           +++RG+SI E       AK S  +       +LL+ G++P+  Q+      ++    +  
Sbjct:  41 LKYRGYSIAELA-----AKSSFLETT-----YLLIWGDLPSSKQLREFEDAIQMHRRLSF  90

Query: 160 EVLRLLDELPHERMHPMTQF-SVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIA 218
            V  ++   P    HPM    S A SL    S+ A    Q         Y  +  + LIA
Sbjct:  91 RVRDMMKCFP-ATGHPMDALQSSAASLGLFYSRRAIDNPQ---------YIYDAVVRLIA 140

Query: 219 RLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELM-RLY---LVL 274
           ++P + A         G+    + I+  DD+             E D L  R++   L+L
Sbjct: 141 KIPTMVAAF--QLIRKGQ----DPIQPRDDLPYSANFLYMLTEREPDPLAARVFDRCLIL 194

Query: 275 HADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGN 334
           HA+H   N S  + R+  S L+DPY   A+ +  LAGPLHG AN++V    + M E++G 
Sbjct: 195 HAEHSL-NASTFSARVTASTLTDPYAVVASAVGTLAGPLHGGANEDV----IAMLEEIG- 248

Query: 335 RPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSK- 393
                EN R    + + +   I GFGH   +  DPR T  + FA      +++F    K 
Sbjct: 249 ---APENARNYLKQAIDQKSKIMGFGHREYKVKDPRATLLQGFA------EDLFARFGKD 299

Query: 394 -LYEVVPRVLEEQGKVKNP---WPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSS 449
            +Y+V   V EE   +  P   +PNVD +SG++ R  G +  + +T +F +SR  G L+ 
Sbjct: 300 EMYDVARSVEEEASPLLGPRGIYPNVDFYSGLVYRKLG-IPRDLFTPIFAISRVAGWLAH 358

Query: 450 LVWDRALGLP-IERPKSVTT 468
             W   L    I RP  + T
Sbjct: 359 --WREQLSANRIFRPTQIYT 376


gb|AAP30803.1| citrate synthase [Candidatus Rickettsia tarasevichiae]
(397 aa)

Score: 95 bits (237), Expect: 2.52051e-18
Length: 435, Idn/Pos/Gap = 110/195/68 (25%/44%/15%)

Query:  60 VRERFGEEVLDACTVNQAYG------GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQR 112
           ++   GE+V+D   V+          G  S  +     + +D  +GI R RG+ I     
Sbjct:   3 LKASIGEDVIDISRVSSEADCFTYDPGFMSTASCRSTITYIDGDKGILRHRGYDI-----  57

Query: 113 LLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHER 172
                K   E+     + +LL+ GE+P+  Q      +  ++ AV          L +ER
Sbjct:  58 -----KDLAEKSDFLEVAYLLIYGELPSSEQY----NNFTKKVAV--------HSLMNER 100

Query: 173 MHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLE--------DALTLIARLPAVA 224
           +H + Q     +       MA   A     S F+   L+         A+ +IA++P +A
Sbjct: 101 LHYLFQ-----TFCNSSHPMAIMLAAVGSLSAFYPDLLKFKEADYELTAIRMIAKIPTIA 155

Query: 225 ARIYRNTFHGGKHVPAEKIEKVDD-MGMRLARS-LGFELNEF--DELMRLYLVLHADHEG 280
           A  Y+ +       P   ++  ++ + M  A     +E+N    + L +++ +LHADHE 
Sbjct: 156 AMSYKYSIGQPFIYPDNSLDFTENFLRMMFATPCTKYEVNPVIKNALNKIF-ILHADHEQ 214

Query: 281 GNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTE 340
            N S   VR+ GS+ ++P+   + G+  L GP HG AN+ V    + M +++G    ++E
Sbjct: 215 -NASTSTVRIAGSSGANPFACISTGIASLWGPAHGGANEAV----INMLKEIG----SSE 265

Query: 341 NLRELCWETLREGHV--IPGFGHAVLRRTDPRYTAQREF---ALKHLPHDEMFQLVSKLY 395
           N+ +   +   +     + GFGH V +  DPR    +E     LK L   E   L+    
Sbjct: 266 NIPKYIAKAKDKDDPFRLMGFGHRVYKNYDPRAAVLKETCKEVLKELGQLENNPLLQIAI 325

Query: 396 EVVPRVLEEQGKVKNP-WPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDR 454
           E+    L+++  ++   +PNVD +SGI+ +  G + S  +TVLF ++R +G ++   W  
Sbjct: 326 ELEASALKDEYFIERKLYPNVDFYSGIIYKAMG-IPSQMFTVLFAIARTVGWMAQ--WKE 382

Query: 455 ALGLP---IERPKSV 466
               P   I RP+ +
Sbjct: 383 MHEDPEQKISRPRQL 397


ref|ZP_00340879.1| COG0372: Citrate synthase [Rickettsia akari str. Hartford]
(435 aa)

Score: 95 bits (237), Expect: 2.5844e-18
Length: 470, Idn/Pos/Gap = 111/206/72 (23%/43%/15%)

Query:  36 TSSATSLQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYG------GMRSLKAMVY  89
           T+   S  E    KI     Q+  ++   GE+V+D   V+          G  S  +   
Sbjct:   2 TNDNDSDSEFAELKIRGKIFQLPILKASIGEDVIDISRVSAEVNCFTYDPGFMSTASCKS  61

Query:  90 ETSLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVC 148
             + +D  +GI R RG++I          K   E+     + +LL+ GE+P+  Q  +  
Sbjct:  62 TITYIDGDKGILRHRGYNI----------KDLAEKSDFLEVAYLLIYGELPSIEQYNNFT 111

Query: 149 QDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEY 208
           + +   + V            +ER+H + Q     +       MA   A     S F+  
Sbjct: 112 KQVAHHSLV------------NERLHYLFQ-----TFCSSSHPMAIMLAAIGSLSAFYPD 154

Query: 209 CLE--------DALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDD-MGMRLARS-LG 258
            L          A+ +IA++P +AA  Y+ +       P   ++  ++ + M  A     
Sbjct: 155 LLNFKEADYELTAIRMIAKIPTIAAMSYKYSIGQPFVYPDNSLDFTENFLHMMFATPCTK 214

Query: 259 FELNEF--DELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGL 316
           +++N    + L +++ +LHADHE  N S   VR+ GS+ ++ +   + G+  L GP HG 
Sbjct: 215 YKVNPIIKNALNKIF-ILHADHEQ-NASTSTVRIAGSSGANAFACISTGIASLWGPAHGG 272

Query: 317 ANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHV--IPGFGHAVLRRTDPRYTAQ 374
           AN+ V    + M +++G    ++EN+ +   +   +     + GFGH V +  DPR +  
Sbjct: 273 ANEAV----INMLKEIG----SSENIPKYIAKAKDKSDPFRLMGFGHRVYKNYDPRASVL 324

Query: 375 REFA------LKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGL 428
           +E        L  L ++ + Q+  +L  +  +  +E    +  +PNVD +SGI+ +  G 
Sbjct: 325 KETCKEVLKELGQLENNPLLQIAIELEAIALK--DEYFIERKLYPNVDFYSGIIYKAMG- 381

Query: 429 VESNFYTVLFGVSRALGTLSSLVWDRAL---GLPIERPKSVTTQWIREHF 475
           + S  +TVLF ++R +G ++   W       G  I RP+ + T ++   +
Sbjct: 382 IPSQMFTVLFAIARTVGWMAQ--WKEMHEDPGQKISRPRQLYTGYVHREY 429


gb|AAN58405.1| citrate synthase [Streptococcus mutans UA159]
ref|NP_721099.1| citrate synthase [Streptococcus mutans UA159]
sp|Q59939|CISZ_STRMU Citrate synthase
(372 aa)

Score: 95 bits (237), Expect: 2.60606e-18
Length: 327, Idn/Pos/Gap = 91/146/30 (27%/44%/9%)

Query: 127 EGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLL 186
           E +++LL    +PT  +++   + L++  A+   + + +     + +HPM+     VSLL
Sbjct:  43 EEVIYLLWNLHLPTAIELKQFEEKLRKNYAISDAIEQCILIQSRQHLHPMSVLRSTVSLL 102

Query: 187 QHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKV 246
              +  AE  +         E   + ++ L+A++P + A   R         P + +   
Sbjct: 103 GVYNLKAEERSV--------EATYDQSIQLMAKIPTIIATFARLRQGLSPIAPRKDLGFA 154

Query: 247 DDMGMRLARSLGFELNEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGL 306
            +    L   L  EL      M   LVLHA+HE  N S  A R+  S LSD Y      +
Sbjct: 155 ANFLYMLNGRLPSELEIL--AMNRALVLHAEHEL-NASTFAARVCASTLSDIYSCVTTAI 211

Query: 307 NGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRR 366
             L GPLHG AN+ V   L +++E          ++     E L     I GFGH V + 
Sbjct: 212 GTLKGPLHGGANERVFDMLREIRE--------YGDVDSYLQEKLNSKEKIMGFGHRVYQT 263

Query: 367 TDPRYTAQREFA---LKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILL 423
            DPR    RE A    K   HD  +QL SK  E+  +      + KN  PNVD +S  + 
Sbjct: 264 QDPREKYLREMARELTKGTEHDIWYQL-SKKVEICMK------QKKNLIPNVDFYSATVY 316

Query: 424 RYYGLVESNFYTVLFGVSRALGTLSSL 450
              G ++S+ +T++F +SR  G ++ +
Sbjct: 317 HVLG-IDSSIFTLIFAMSRVSGWIAHI 342


ref|YP_179942.1| citrate synthase [Ehrlichia ruminantium str. Welgevonden]
emb|CAI26563.1| Citrate synthase [Ehrlichia ruminantium str. Welgevonden]
emb|CAI27518.1| Citrate synthase [Ehrlichia ruminantium str. Gardel]
emb|CAH57787.1| citrate synthase [Ehrlichia ruminantium str. Welgevonden]
gb|AAL01664.1| citrate synthase [Cowdria ruminantium]
ref|YP_195992.1| Citrate synthase [Ehrlichia ruminantium str. Gardel]
ref|YP_196945.1| Citrate synthase [Ehrlichia ruminantium str. Welgevonden]
(415 aa)

Score: 95 bits (237), Expect: 2.71708e-18
Length: 427, Idn/Pos/Gap = 106/190/65 (24%/44%/15%)

Query:  65 GEEVLDACTVNQAYG------GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQRLLPRA 117
           G EVLD  ++ +  G      G  S  A   + + +D  +GI R+RG+ I +   L+   
Sbjct:  24 GNEVLDITSLYKNTGVLTYDPGFMSTAACESKITFIDGNKGILRYRGYDIAD---LVYNN  80

Query: 118 KPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMT 177
           K   E      +++LL  G  P   Q++     + +   +P  V  ++   P +  HPM 
Sbjct:  81 KSFIE------VVYLLFYGVFPNAEQLQEFILHISQEYVLPQMVRDVITSFP-QNSHPMA 133

Query: 178 QFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKH 237
                  L+   S +A  Y             LE  L  +A++ ++ A IYR       H
Sbjct: 134 ------ILIASFSSLAAYYCDQKTDGE-----LECKLA-VAKVASIVALIYR-------H 174

Query: 238 VPAEKIEKVDDMGMRLARS---LGFELNEF------DELMRLYLVLHADHEGGNVSAHAV 288
           +  +   + D +G+  +++   + F+++ +      D+ + +  VLHADHE  N S   V
Sbjct: 175 ITNQDFIQAD-VGLSYSKNFIHMMFDISSYKFTEIVDKALDVIFVLHADHEQ-NASTATV 232

Query: 289 RLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWE 348
           R+ GS+  + +   AAG   L GP HG AN+ V+  L+ +      +P   +   +   +
Sbjct: 233 RMTGSSGPNLFACLAAGAATLWGPAHGGANEAVINMLMNI-----GKPENVKQFIQKVKD 287

Query: 349 TLREGHVIPGFGHAVLRRTDPRY----TAQREFALKHLPHDEMFQLVSKLYEVVPRVLEE 404
           + +   ++ GFGH V +  DPR     T  +E       +D + ++  +L  +   + ++
Sbjct: 288 SNKSTKLM-GFGHRVYKNYDPRARIMCTICKEILKDFGLNDPLLEVAVELENIA--LQDD 344

Query: 405 QGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALG---LPIE 461
               +N +PNVD +SGI+L+  G +    +T LF ++R  G   S  W   +      I 
Sbjct: 345 YFIARNLYPNVDFYSGIVLKTIG-IPVKMFTTLFALARTSGW--SAQWYEMVSSKNYKIS 401

Query: 462 RPKSVTT 468
           RP+ + T
Sbjct: 402 RPRQLYT 408


gb|AAD07097.1| citrate synthase (gltA) [Helicobacter pylori 26695]
pir||B64523 citrate synthase - Helicobacter pylori (strain 26695)
ref|NP_206828.1| citrate synthase (gltA) [Helicobacter pylori 26695]
sp|P56062|CISY_HELPY Citrate synthase
(426 aa)

Score: 95 bits (236), Expect: 2.8805e-18
Length: 363, Idn/Pos/Gap = 104/167/56 (28%/46%/15%)

Query: 132 LLLTGEIPTESQVESVC--QDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQ-- 187
           LLLTGE+P ++Q ES+    +L+ R+ V   +L +    P    HPM + S  VS+L   
Sbjct:  88 LLLTGELP-KNQDESLEFELELRHRSFVHESLLNMFSAFP-SNAHPMAKLSSGVSILSTL 145

Query: 188 ---HESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIE 244
              H++   E   Q              A  ++A++P +AA  YRN        P     
Sbjct: 146 YSTHQNMHTEEDYQTM------------ARRIVAKIPTLAAICYRNEVGAPIIYPDIARS 193

Query: 245 KVDDMGMRL---------------ARSLGFELNEFDELMRLYLVLHADHEGGNVSAHAVR 289
            V+++   L                     E+  FD++    L LHADH   N S+  VR
Sbjct: 194 YVENILFMLRGYPYSRLKHTTQGEVEITPLEVEAFDKI----LTLHADHSQ-NASSTTVR 248

Query: 290 LVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWET 349
            V S    PY + +AG++ L G LHG AN++V   LLQ+ E++G+     + +  +  + 
Sbjct: 249 NVASTGVHPYAAISAGISALWGHLHGGANEKV---LLQL-EEIGDVKNVDKYIARV--KD 302

Query: 350 LREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSKLYEVVPRVLE-----E 404
             +   + GFGH V +  DPR  A+    LK   H +  ++  +L E+  +V E     E
Sbjct: 303 KNDNFKLMGFGHRVYKSYDPR--AKILKGLKDELHQKGVKMDERLSEIAAKVEEIALKDE 360

Query: 405 QGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWD-RALGLPIERP 463
               +N +PNVD +SG +LR    +   F+T +F + R +G  + L+   ++    I RP
Sbjct: 361 YFIERNLYPNVDFYSGTILRALK-IPVRFFTPVFVIGRTVGWCAQLLEHVKSPQARITRP 419

Query: 464 KSV 466
           + V
Sbjct: 420 RQV 422


emb|CAE42630.1| citrate synthase [Bordetella pertussis Tohama I]
ref|NP_880994.1| citrate synthase [Bordetella pertussis Tohama I]
(436 aa)

Score: 95 bits (236), Expect: 2.8805e-18
Length: 353, Idn/Pos/Gap = 92/163/32 (26%/46%/9%)

Query: 129 LLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQH 188
           + +L+L GE+P   Q +     +     V  ++   L     +  HPM   +  V  L  
Sbjct:  90 ICYLILNGELPNGGQKQDFDSQVTHHTMVNEQLHFFLRGFRRD-AHPMAVLTGLVGALS- 147

Query: 189 ESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDD 248
                 A+   +   T   +    A+ LIA++P + A  Y+ +       P   +    +
Sbjct: 148 ------AFYHDSTDITNPHHRHVSAIRLIAKMPTLVAMAYKYSQGQPFIYPQNDLSYTGN 201

Query: 249 MGMRLARSLGFELNEFDELMRLYL----VLHADHEGGNVSAHAVRLVGSALSDPYLSFAA 304
             +R+  +   E  + ++++   L    +LHADHE  N S   VRL GS+ ++P+ + AA
Sbjct: 202 F-LRMMCATPCEEYKVNDVVERALDRIFILHADHEQ-NASTSTVRLCGSSGTNPFAAIAA 259

Query: 305 GLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVL 364
           G+  L GP HG AN+  L+ L +++   G      E + ++  +    G  + GFGH V 
Sbjct: 260 GVACLWGPAHGGANEACLQMLEELQAN-GGVAKVGEFMEKV--KDKNSGVRLMGFGHRVY 316

Query: 365 RRTDPRYTAQRE-----FALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNP-WPNVDQH 418
           +  DPR    +E          L +D +F+L  +L  +    LE+   V+   +PNVD +
Sbjct: 317 KNYDPRAKLMQETCKEVLVALGLENDPLFKLAMELERI---ALEDDYFVQRKLYPNVDFY 373

Query: 419 SGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPKSVTT 468
           SGI+ R  G + ++ +T +F ++R +G ++   W+  L  P   I RP+ + T
Sbjct: 374 SGIVQRAIG-IPTSLFTAIFALARTVGWIAQ--WNEMLSDPDYKIGRPRQLFT 423


ref|NP_834300.1| Citrate synthase [Bacillus cereus ATCC 14579]
gb|AAP11501.1| Citrate synthase [Bacillus cereus ATCC 14579]
(371 aa)

Score: 95 bits (236), Expect: 2.95351e-18
Length: 334, Idn/Pos/Gap = 91/152/42 (27%/45%/12%)

Query: 127 EGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLL 186
           E +++LL   ++P E ++    + +     VP E+L  L ++  +  HPM+    A+S+L
Sbjct:  42 EEVVYLLWHRKLPNEKELAEFNEIVSEYYKVPGEILTYLKQVDLKIAHPMSVLRTAISML 101

Query: 187 QHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKV 246
               + AE   +   KS + +     A   +  L A  ARI +           + +E  
Sbjct: 102 SLYDESAEIMDE---KSNYLKAVKLQAQ--VGTLVAAYARIRKGL---------DIVEPR 147

Query: 247 DDMGMRLARSLGFELNEFD------ELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYL 300
            D+   LA +  + LN+ +      E     LVLHADHE  N S    R+  + LSD Y 
Sbjct: 148 KDLS--LAANFLYMLNDREPNEVEIEAFDKALVLHADHEL-NASTFTARVCVATLSDVYS 204

Query: 301 SFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFG 360
              A +  L GPLHG AN+ V++ L ++ E+        EN+       L+    I GFG
Sbjct: 205 GITAAIGALKGPLHGGANENVMKMLTEIGEE--------ENVESYIHNALQNKVKIMGFG 256

Query: 361 HAVLRRTDPRYTAQREFALK---HLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQ 417
           H V  + DPR    RE + +    L  ++ + +  K+ ++V        K K   PNVD 
Sbjct: 257 HRVYEQGDPRAKHLREMSKRLCVLLGEEKWYNMSIKIEDIVT-------KEKGLPPNVDF 309

Query: 418 HSGILLRYYGLVESNFYTVLFGVSRALGTLSSLV 451
           +S  +    G ++ + +T +F +SR  G L+ ++
Sbjct: 310 YSASVYHCLG-IDHDLFTPIFAISRMSGWLAHIL 342


ref|NP_981018.1| citrate synthase CitZ [Bacillus cereus ATCC 10987]
gb|AAS43626.1| citrate synthase CitZ [Bacillus cereus ATCC 10987]
(371 aa)

Score: 95 bits (236), Expect: 2.97826e-18
Length: 334, Idn/Pos/Gap = 91/152/42 (27%/45%/12%)

Query: 127 EGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLL 186
           E +++LL   ++P E ++    + +     VP E+L  L ++  +  HPM+    A+S+L
Sbjct:  42 EEVVYLLWHRKLPNEQELAEFKEIVSEYYKVPGEILAYLKQVDLKIAHPMSVLRTAISML 101

Query: 187 QHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKV 246
               + AE   +   KS + +     A   +  L A  ARI +           + +E  
Sbjct: 102 SLYDESAEIMDE---KSNYLKAVKLQAQ--VGTLVAAYARIRKGL---------DVVEPR 147

Query: 247 DDMGMRLARSLGFELNEFD------ELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYL 300
           +D+   LA +  + LN+ +      E     LVLHADHE  N S    R+  + LSD Y 
Sbjct: 148 NDLS--LAANFLYMLNDREPNEVEIEAFDKALVLHADHEL-NASTFTARVCVATLSDVYS 204

Query: 301 SFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFG 360
              A +  L GPLHG AN+ V++ L ++ E+        EN+       L+    I GFG
Sbjct: 205 GITAAIGALKGPLHGGANENVMKMLTEIGEE--------ENVESYIHNALQNKVKIMGFG 256

Query: 361 HAVLRRTDPRYTAQREFALK---HLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQ 417
           H V    DPR    RE + +    L  ++ + +  K+ ++V        K K   PNVD 
Sbjct: 257 HRVYEHGDPRAKHLREMSKRLCVLLGEEKWYNMSIKIEDIVT-------KEKGLPPNVDF 309

Query: 418 HSGILLRYYGLVESNFYTVLFGVSRALGTLSSLV 451
           +S  +    G ++ + +T +F +SR  G L+ ++
Sbjct: 310 YSASVYHCLG-IDHDLFTPIFAISRMSGWLAHIL 342


emb|CAB84410.1| putative citrate synthase [Neisseria meningitidis Z2491]
gb|AAF41360.1| citrate synthase [Neisseria meningitidis MC58]
ref|NP_283916.1| citrate synthase [Neisseria meningitidis Z2491]
pir||B81139 probable citrate (si)-synthase (EC 4.1.3.7) NMA1148 [imported] - Neisseria meningitidis (strain MC58 serogroup B, strain Z2491 serogroup A)
ref|NP_273992.1| citrate synthase [Neisseria meningitidis MC58]
(427 aa)

Score: 95 bits (236), Expect: 3.02837e-18
Length: 357, Idn/Pos/Gap = 101/165/49 (28%/46%/13%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LL+ GE+PT  Q       ++R   V  ++         +  HPM      V  L    
Sbjct:  88 YLLIYGELPTPEQKAEFDNTVRRHTMVHEQLTWFFRGFRRD-AHPMAMMVGVVGALS--- 143

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDD-M 249
               A+ Q +   +  E+       LI+++P +AA  YR +     + P   +   ++ +
Sbjct: 144 ----AFYQDSLDISNPEHRKIAIYRLISKIPTIAAMCYRYSNGLPFNYPKNNLSYSENFL 199

Query: 250 GMRLARSL-GFELNEF--DELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGL 306
            M  A     ++ N      L R++ +LHADHE  N S   VRL GS+ ++P+   AAG+
Sbjct: 200 HMMFATPCEDYKPNPVLARALDRIF-ILHADHEQ-NASTSTVRLAGSSGANPFACIAAGI 257

Query: 307 NGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRR 366
             L G  HG AN+ VL+ L ++ + + N     E +++  +  +       GFGH V R 
Sbjct: 258 ACLWGASHGGANEAVLKMLDEIGD-VSNVAAYMEGVKQRKYRLM-------GFGHRVYRN 309

Query: 367 TDPRYTAQREF---ALKHLPHDE--MFQLVSKLYEVVPRVLEEQGKVKNP-------WPN 414
            DPR +  RE     LK L  ++   F+L  +L         EQ  +K+P       +PN
Sbjct: 310 MDPRASIMRETCYEVLKELGLEDSPKFKLAMEL---------EQIALKDPFFIERKLYPN 360

Query: 415 VDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPKSVTT 468
           VD +SGI+L   G + +  +TV+F +SR++G +S   W   +  P   I RP+ + T
Sbjct: 361 VDFYSGIVLSALG-IPTEMFTVIFALSRSVGWISH--WHEMISDPSLKIGRPRQLYT 414


gb|AAC44825.1| citrate synthase
(372 aa)

Score: 95 bits (236), Expect: 3.18384e-18
Length: 327, Idn/Pos/Gap = 90/146/30 (27%/44%/9%)

Query: 127 EGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLL 186
           E +++LL    +PT  +++   + L++  A+   + + +     + +HPM+     VSLL
Sbjct:  43 EEVIYLLWNLHLPTAIELKQFEEKLRKNYAISDAIEQCILIQSRQHLHPMSVLRSTVSLL 102

Query: 187 QHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKV 246
              +  AE  +         E   + ++ L+A++P + A   R         P + +   
Sbjct: 103 GVYNLKAEERSV--------EATYDQSIQLMAKIPTIIATFARLRQGLSPIAPRKDLGFA 154

Query: 247 DDMGMRLARSLGFELNEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGL 306
            +    L   L  EL      M   LVLHA+HE  N S  A R+  S LSD Y      +
Sbjct: 155 ANFLYMLNGRLPSELEIL--AMNRALVLHAEHEL-NASTFAARVCASTLSDIYSCVTTAI 211

Query: 307 NGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRR 366
             L GPLHG AN+ V   L +++E          ++     E L     I GFGH V + 
Sbjct: 212 GTLKGPLHGGANERVFDMLREIRE--------YGDVDSYLQEKLNSKEKIMGFGHRVYQT 263

Query: 367 TDPRYTAQREFA---LKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILL 423
            DPR    RE A    K   HD  +QL  K    V   ++++   KN  PNVD +S  + 
Sbjct: 264 QDPREKYLREMARELTKGTEHDIWYQLSKK----VEMCMKQK---KNLIPNVDFYSATVY 316

Query: 424 RYYGLVESNFYTVLFGVSRALGTLSSL 450
              G ++S+ +T++F +SR  G ++ +
Sbjct: 317 HVLG-IDSSIFTLIFAMSRVSGWIAHI 342


ref|NP_892282.1| Citrate synthase [Prochlorococcus marinus subsp. pastoris str. CCMP1986]
emb|CAE18620.1| Citrate synthase [Prochlorococcus marinus subsp. pastoris str. CCMP1986]
(381 aa)

Score: 95 bits (236), Expect: 3.43213e-18
Length: 388, Idn/Pos/Gap = 106/175/58 (27%/45%/14%)

Query:  94 LDPQEG-IRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLK 152
           +D Q+G + +RG+SI E  +     + +          +LL+ GE+P+ +++    Q+++
Sbjct:  25 IDGQKGKLLYRGYSIEELAQKSSFLETA----------FLLIWGELPSATELRDFEQEVQ  74

Query: 153 RRAAVPPEVLRLLDELPHERMHPMTQF-SVAVSLLQHESKMAEAYAQGAPKSTFWEYCLE 211
               +   V  ++   P    HPM    S A SL    S+ A       PK     Y   
Sbjct:  75 MHRRLSFRVRDMMKCFP-ATGHPMDALQSSAASLGLFYSRRA----IDDPK-----YIYN 124

Query: 212 DALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDE----- 266
             + LIA++P + A         G+    + I+  DD+    + +  + L E ++     
Sbjct: 125 AVIRLIAKIPTMIAAF--QLIRKGQ----DPIQPRDDLSY--SSNFLYMLTEKEQDPIAA 176

Query: 267 -LMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWL 325
            +    L+LHA+H   N S  + R+  S L+DPY   A+ +  LAGPLHG AN++V+  L
Sbjct: 177 KVFDRCLILHAEHSL-NASTFSARVTASTLTDPYAVIASAVGTLAGPLHGGANEDVIAML 235

Query: 326 LQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFA---LKHL 382
             +K        T E       + ++    I GFGH   +  DPR    ++ A       
Sbjct: 236 EDIK--------TPEKAASFLEDAIQNKSKIMGFGHREYKVKDPRAIILQKLAEELFVRF 287

Query: 383 PHDEMFQLVSKL-YEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVS 441
             DEM+++  KL  E +PR+       K  +PNVD +SG++ R  G +  + +T +F +S
Sbjct: 288 GKDEMYEVAKKLELEAIPRL-----GGKGIFPNVDFYSGLVYRKLG-IPRDLFTPIFAIS 341

Query: 442 RALGTLSSLVWDRALGLP-IERPKSVTT 468
           R  G L+   W   LG   I RP  + T
Sbjct: 342 RVAGWLAH--WREQLGANRIFRPSQIYT 367


gb|EAA25990.1| citrate synthase [Rickettsia sibirica 246]
ref|ZP_00142581.1| citrate synthase [Rickettsia sibirica 246]
(435 aa)

Score: 95 bits (236), Expect: 3.48989e-18
Length: 445, Idn/Pos/Gap = 104/195/68 (23%/43%/15%)

Query:  60 VRERFGEEVLDACTVNQAYG------GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQR 112
           ++   GE+V+D   V+          G  S  +     + +D  +GI R RG+ I     
Sbjct:  26 LKASIGEDVIDISRVSAEADCFTYDPGFMSTASCQSTITYIDGDKGILRHRGYDI-----  80

Query: 113 LLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHER 172
                K   E+     + +LL+ GE+P+  Q  +  + +   + V            +ER
Sbjct:  81 -----KDLAEKSDFLEVAYLLIYGELPSGEQYNNFTKQVAHHSLV------------NER 123

Query: 173 MHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLE--------DALTLIARLPAVA 224
           +H + Q     +       MA   A     S F+   L          A+ +IA++P +A
Sbjct: 124 LHYLFQ-----TFCSSSHPMAIMLAAVGSLSAFYPDLLNFKEADYELTAIRMIAKIPTIA 178

Query: 225 ARIYRNTFHGGKHVPAEKIEKVDD-MGMRLARS-LGFELNEF--DELMRLYLVLHADHEG 280
           A  Y+ +       P   ++  ++ + M  A     + +N    + L +++ +LHADHE 
Sbjct: 179 AMSYKYSIGQPFIYPDNSLDFTENFLHMMFATPCTKYTVNPIIKNALNKIF-ILHADHEQ 237

Query: 281 GNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTE 340
            N S   VR+ GS+ ++P+   + G+  L GP HG AN+ V    + M +++G+     +
Sbjct: 238 -NASTSTVRIAGSSGANPFACISTGIASLWGPAHGGANEAV----INMLKEIGSSEYIPK 292

Query: 341 NLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFA------LKHLPHDEMFQLVSKL 394
            + +   +   +   + GFGH V +  DPR    +E        L  L ++ + Q+  +L
Sbjct: 293 YIAKA--KDKNDPFRLMGFGHRVYKNYDPRAAVLKETCKEVLKELGQLDNNPLLQIAIEL 350

Query: 395 YEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDR 454
             +  +  +E    +  +PNVD +SGI+ +  G + S  +TVLF ++R +G ++   W  
Sbjct: 351 EAIALK--DEYFIERKLYPNVDFYSGIIYKAMG-IPSQMFTVLFAIARTVGWMAQ--WKE 405

Query: 455 ALGLP---IERPKSVTTQWIREHFE 476
               P   I RP+ + T ++   ++
Sbjct: 406 MHEDPEQKISRPRQLYTGYVHREYK 430


emb|CAF18490.1| citrate synthase 2 [Thermoproteus tenax]
(410 aa)

Score: 95 bits (235), Expect: 4.12367e-18
Length: 349, Idn/Pos/Gap = 99/153/45 (28%/43%/12%)

Query: 116 RAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHP 175
           R +   E    E +++LLL G++P+  ++  +   L     + P  + +L  L   + HP
Sbjct:  52 RIEDLAENTTYEEVVYLLLYGKLPSARELADIKSRLSANRELNPATIEILRALA--KAHP 109

Query: 176 MTQFSVAVS----LLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNT 231
           M     AV+      +   K+A+A   G  K    +  L  A  LIA+LP + A  YR  
Sbjct: 110 MFALEAAVASEGAFDEDNLKLADALRAGRYKQEEKDLALRIAEKLIAKLPTIVAYHYR-- 167

Query: 232 FHGGKHVPAEKIEKVDDMGMRLARSLGFEL----NEFDEL----MRLYLVLHADHEGGNV 283
                   +  +E V   G  LA S  F       E D L    + LYL+LHADHE    
Sbjct: 168 -------LSRGLELVRPRG-DLAHSANFLYMFFGKEPDPLATKAIDLYLILHADHEI-PA 218

Query: 284 SAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLR 343
           S     ++G+ LSD Y   A  +  L GPLHG AN+  ++  L++ +     P   + + 
Sbjct: 219 STFTALVIGATLSDLYSVIAGAIGALKGPLHGGANEAAVKSYLEIAD-----PSKAKEIV 273

Query: 344 ELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSKLYEVVPRVLE 403
           E    T   G  + G GH V +  DPR    ++    +      F    +LY +   +  
Sbjct: 274 EAA--TKPGGPRLMGVGHRVYKAYDPRAKIFKKLVEDYTAK---FGDPQRLYAIASNI-- 326

Query: 404 EQGKVKNP-------WPNVDQHSGILLRYYGLVESNFYTVLFGVSRALG 445
           EQ  + +P       +PNVD  SGI+  Y G +  +++T LF +SR  G
Sbjct: 327 EQAVMAHPYFQQRKLYPNVDFWSGIVFYYMG-IPYDYFTPLFAMSRVAG 374


ref|NP_717533.1| citrate synthase [Shewanella oneidensis MR-1]
gb|AAN54977.1| citrate synthase [Shewanella oneidensis MR-1]
(428 aa)

Score: 95 bits (235), Expect: 4.67346e-18
Length: 344, Idn/Pos/Gap = 95/154/32 (27%/44%/9%)

Query: 136 GEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEA 195
           GE+PT+ Q       +K    V  ++         +  HPM         L        A
Sbjct:  93 GELPTKEQYAEFVHTVKTHTMVHEQIAFFFRGFRRD-AHPMAMLCGVTGALS-------A 144

Query: 196 YAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDD-MGMRLA 254
           + Q +       +    A  L++++P +AA  Y+ +       P   +    + + M  A
Sbjct: 145 FYQDSLDVNDPRHREIAAYRLVSKMPTIAAMCYKYSSGQPFVYPRNDLSYAGNFLSMMFA 204

Query: 255 RSLG-FELNEFDE-LMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGP 312
                +++N   E  M    +LHADHE  N S   VRL GS+ ++P+   AAG+  L GP
Sbjct: 205 VPCEEYKVNPIVERAMDRIFILHADHEQ-NASTSTVRLAGSSGANPFACIAAGIASLWGP 263

Query: 313 LHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYT 372
            HG AN+      LQM E++G+     E +     +   +   + GFGH V +  DPR  
Sbjct: 264 AHGGANEAC----LQMLEEIGSVDRIPEFIARA--KDKNDPFRLMGFGHRVYKNFDPRAK 317

Query: 373 AQREF---ALKHLP-HDEMFQLVSKLYEVVPRVLEEQGKV-KNPWPNVDQHSGILLRYYG 427
             RE     LK L   D +  +  +L  +    LE++  + K  +PNVD +SGI+++  G
Sbjct: 318 VMRETCHEVLKELKVQDPLLDVAMELERI---ALEDEYFISKKLYPNVDFYSGIIMKAIG 374

Query: 428 LVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPKSVTT 468
            + ++ +TVLF +SR +G ++   W   L  P   I RP+ + T
Sbjct: 375 -IPTSMFTVLFALSRTVGWIAH--WKEMLDQPGHKISRPRQLYT 415


ref|ZP_00006869.2| COG0372: Citrate synthase [Rhodobacter sphaeroides 2.4.1]
(428 aa)

Score: 94 bits (234), Expect: 4.79192e-18
Length: 348, Idn/Pos/Gap = 98/158/33 (28%/45%/9%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LLL GE+P  +Q       + R   +  ++         +  HPM      V       
Sbjct:  87 YLLLYGELPNAAQQADFEYRITRHTMLHEQIHYFFRGFRRDS-HPMATMVGVVG------ 139

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDD-M 249
            M+  Y      +  W+  +  A+ +IA+LP +AA  Y+ +     + P   ++   + +
Sbjct: 140 AMSAFYHDSLDINDPWQREVA-AIRMIAKLPTIAAMAYKYSIGQPFNYPQNHLDYAGNFL 198

Query: 250 GMRLA-RSLGFELNE-FDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLN 307
            M  A  +  + +N    + M   ++LHADHE  N S   VRL GS+ ++P+   AAG+ 
Sbjct: 199 HMCFAVPAEPYTVNPVLAKAMDRIMMLHADHEQ-NASTSTVRLAGSSGANPFACIAAGIA 257

Query: 308 GLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRT 367
            L GP HG AN    R  L+M  ++G      E +R    +   +   + GFGH V +  
Sbjct: 258 CLWGPAHGGAN----RACLEMLREIGTVDRIPEYIRRA--KDKDDPFRLMGFGHRVYKNF 311

Query: 368 DPRYTAQREFA-----LKHLPHDEMFQLVSKLYEVVPRVLEEQGKV-KNPWPNVDQHSGI 421
           DPR    +E A     L  + ++   Q+  +L  +    LE+   V K  +PNVD +SGI
Sbjct: 312 DPRAKVMKESADEVLGLLGIENNPTLQVAKELERI---ALEDDYFVAKKLYPNVDFYSGI 368

Query: 422 LLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPKSV 466
           +L   G   S F T +F +SR +G +S   W   +G P   I RP+ +
Sbjct: 369 ILDAMGFPTSMF-TPIFAISRTVGWISQ--WKEMIGDPTQKIGRPRQL 413


ref|ZP_00168160.2| COG0372: Citrate synthase [Ralstonia eutropha JMP134]
(433 aa)

Score: 94 bits (234), Expect: 4.87256e-18
Length: 352, Idn/Pos/Gap = 98/163/41 (27%/46%/11%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPM---TQFSVAVSLLQ 187
           +LLL GE+P   Q E     +     V  ++   L     +  HPM   T    A+S   
Sbjct:  92 YLLLKGELPNAKQKEEFTGHVMNHTMVHEQLQFFLRGFRRD-AHPMAVLTGLVGAMSAFY 150

Query: 188 HESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVD 247
           H++   +   Q              A+ LIA++P + A  Y+         P   +    
Sbjct: 151 HDAMDIDDPHQREIS----------AIRLIAKMPTMVAMAYKYNIGQPYIYPQNDLSYSG 200

Query: 248 DMGMRL--ARSLGFELNEFDE--LMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFA 303
           +    L       + +N   E  L R++ +LHADHE  N S   VRL GS+ ++P+ + A
Sbjct: 201 NFLRMLFGTPCAPYTVNPVLERALDRIF-ILHADHEQ-NASTSTVRLAGSSGTNPFAAIA 258

Query: 304 AGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAV 363
           AG+  L GP HG AN+  L+    M E++G+     E ++++  +    G  + GFGH V
Sbjct: 259 AGVACLWGPAHGGANEAALK----MLEEIGSVDNIGEFIKQV--KDKNSGVRLMGFGHRV 312

Query: 364 LRRTDPRYTAQREFALK-----HLPHDEMFQLVSKLYEVVPRVLEEQGKV-KNPWPNVDQ 417
            +  DPR    RE   +      L +D +F+L  +L ++    LE++  V +  +PNVD 
Sbjct: 313 YKNYDPRAKLMRETCHEVLNELGLHNDPLFKLAMELEKI---ALEDEYFVSRKLYPNVDF 369

Query: 418 HSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPKSV 466
           +SGI+ R  G + ++ +T +F ++R  G +S   W+  +  P   I RP+ +
Sbjct: 370 YSGIVQRALG-IPTSLFTCIFALARTPGWISQ--WEEMITDPEYKIGRPRQL 418


ref|ZP_00050963.1| COG0372: Citrate synthase [Magnetospirillum magnetotacticum MS-1]
(456 aa)

Score: 94 bits (234), Expect: 4.91338e-18
Length: 396, Idn/Pos/Gap = 100/175/60 (25%/44%/15%)

Query:  92 SLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQD 150
           + +D + GI R+RG+ I +            E+     + +LL+ GE+P  + +++  + 
Sbjct:  85 TYIDGEAGILRYRGYPIEQL----------AERSSFLEVAYLLIHGELPDAATLDAFVER 134

Query: 151 LKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCL 210
           + R   V  +    +   P    HPM   S A++ L                STF+   L
Sbjct: 135 VNRHTLVHEDFRTFMGTFPRN-AHPMAVLSSAINAL----------------STFYPESL 177

Query: 211 ED---------ALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFEL 261
           +           + L+A+   + + ++R         P      VDD  +R+  +  ++ 
Sbjct: 178 DPFDDETVELATVLLLAKSRTITSYLHRRRVGEPLLYPDYSRGYVDDF-LRMTFATPYQQ 236

Query: 262 NEFD----ELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLA 317
            E D    + +   L+LHADHE  N S   VR+VGS+ ++ Y S AAG+N L+GPLHG A
Sbjct: 237 YEADPVVVDALDKLLILHADHEQ-NCSTSTVRVVGSSHANLYASVAAGVNALSGPLHGGA 295

Query: 318 NQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREF 377
           N+ V    L M +K+       +   +   +   +G  + GFGH V +  DPR    ++ 
Sbjct: 296 NESV----LTMLDKIAGAEYDVDTFMKKV-KNKEDGVRLMGFGHRVYKNYDPRAAIVKKS 350

Query: 378 ALKHLP----HDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNF 433
           A   L      D++  +   L E+   + ++    +  +PNVD ++G++ +  G   + F
Sbjct: 351 ADAVLSTLGKKDQLLDIAMGLEEIA--LNDDYFIERKLYPNVDFYTGLIYKAMGFSPAMF 408

Query: 434 YTVLFGVSRALGTLSSLVWDRALGLP---IERPKSV 466
            T LF + R  G ++   W   +  P   I RP+ V
Sbjct: 409 -TPLFALGRMPGWIAQ--WREMMKDPQTKIGRPRQV 441


gb|AAB39736.1| citrate synthase [Bradyrhizobium japonicum]
(434 aa)

Score: 94 bits (234), Expect: 5.1227e-18
Length: 361, Idn/Pos/Gap = 101/164/41 (27%/45%/11%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQ--- 187
           +LLL G +PT +Q +     +     V  ++ R       +  HPM     +V  L    
Sbjct:  92 YLLLYGNLPTAAQKKDFDDRVIHHTMVHEQMARFFQGFRRD-AHPMAVMVASVGALAAFY 150

Query: 188 HESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVD 247
           H+S       Q    S          + +IA++P +AA  Y+ T       P   ++  +
Sbjct: 151 HDSTDINDPKQRMIAS----------MRMIAKIPTLAAMAYKYTIGQPFVYPKNSLKFAE 200

Query: 248 D-MGMRLARSLG-FELNEF--DELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFA 303
           + + M  A S   +++N    D L +++ +LHADHE  N S   VR+ GS+ ++P+   A
Sbjct: 201 NFLHMCFAVSCEEYKINPVLADALDKIF-ILHADHEQ-NASTSTVRIAGSSGANPFACIA 258

Query: 304 AGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAV 363
           AG+  L GP HG AN+  L  L ++   +   P     +++   E       + GFGH V
Sbjct: 259 AGIACLWGPAHGGANEAALAMLGEIGS-VDKIPEFIAKVKDKNSEVR-----LMGFGHRV 312

Query: 364 LRRTDPRYTAQREF---ALKHLPH--DEMFQLVSKLYEVVPRVLEEQGKV-KNPWPNVDQ 417
            +  DPR    ++     LK   H  D M ++  +L ++    L +Q  + +  +PNVD 
Sbjct: 313 YKNYDPRAKIMQKMCHAVLKETGHGDDPMLKVALELEKI---ALSDQYFIDRKLYPNVDF 369

Query: 418 HSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPKSVTTQWIREH 474
           +SGI L+  G   S F TVLF V+R +G +S   W   +  P   I RP+ + T   R  
Sbjct: 370 YSGITLKAMGFPVSMF-TVLFAVARTVGWISQ--WSEMIEDPQQKIGRPRQLYTGVTRRD 426

Query: 475 F 475
           +
Sbjct: 427 Y 427


ref|YP_067768.1| (R)-citric synthase.; Citrate condensing enzyme.; Citrate oxaloacetate-lyase [(pro-3S)-CH(2)COO(-)->acetyl-CoA].; Citrate oxaloacetate-lyase, CoA-acetylating.; Citrate synthase.; Citrate synthetase.; Citric synthase.; Citric-condensing enzyme.; Citrogenase.; Condensing enzyme.; Oxalacetic transacetase.; Oxaloacetate transacetase.; citrate (Si)-synthase [Rickettsia typhi str. Wilmington]
gb|AAU04286.1| citrate (Si)-synthase; (R)-citric synthase.; Citrate condensing enzyme.; Citrate oxaloacetate-lyase [(pro-3S)-CH(2)COO(-)->acetyl-CoA].; Citrate oxaloacetate-lyase, CoA-acetylating.; Citrate synthase.; Citrate synthetase.; Citric synthase.; Citric-condensing enzyme.; Citrogenase.; Condensing enzyme.; Oxalacetic transacetase.; Oxaloacetate transacetase. [Rickettsia typhi str. Wilmington]
sp|P51043|CISY_RICTY Citrate synthase
(436 aa)

Score: 94 bits (234), Expect: 5.80569e-18
Length: 361, Idn/Pos/Gap = 92/169/39 (25%/46%/10%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +L++ GE+P+  Q  +    +   A V  E L  L +      HPM     AV  L    
Sbjct:  94 YLMIYGELPSSEQYHNFTTKIAHHALVN-ERLHYLFQTFCSSSHPMAIMLAAVGSLS--- 149

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDD-M 249
               A+          +Y L  A+ +IA++P +AA  Y+ +       P   ++  ++ +
Sbjct: 150 ----AFYPDLLNFNETDYELT-AIRMIAKIPTIAAMSYKYSIGQPFIYPDNSLDFTENFL 204

Query: 250 GMRLARS-LGFELNEF--DELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGL 306
            M  A     +++N    + L +++ +LHADHE  N S   VR+ GS+ ++P+   + G+
Sbjct: 205 HMMFATPCTKYKVNPIIKNALNKIF-ILHADHEQ-NASTSTVRIAGSSGANPFACISTGI 262

Query: 307 NGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHV--IPGFGHAVL 364
             L GP HG AN+ V    + M +++G    ++EN+ +   +   +     + GFGH V 
Sbjct: 263 ASLWGPAHGGANEAV----INMLKEIG----SSENIPKYVAKAKDKNDPFRLMGFGHRVY 314

Query: 365 RRTDPRYTAQREFA------LKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQH 418
           +  DPR    +E        L  L ++ + Q+  +L  +  +  +E    +  +PNVD +
Sbjct: 315 KSYDPRAAVLKETCKEVLNELGQLENNPLLQIAIELEALALK--DEYFIERKLYPNVDFY 372

Query: 419 SGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPKSVTTQWIREHF 475
           SGI+ +  G + S  +TVLF ++R +G ++   W      P   I RP+ + T ++   +
Sbjct: 373 SGIIYKAMG-IPSQMFTVLFAIARTVGWMAQ--WKEMHEDPEQKISRPRQLYTGYVHREY 429

Query: 476 E 476
           +
Sbjct: 430 K 430


gb|AAF66600.1| citrate synthase [Rickettsia sp. IRS 4]
gb|AAF66554.1| citrate synthase [Rickettsia sp. IRS3]
(410 aa)

Score: 94 bits (233), Expect: 6.20644e-18
Length: 416, Idn/Pos/Gap = 99/185/67 (23%/44%/16%)

Query:  60 VRERFGEEVLDACTVNQAYG------GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQR 112
           ++   GE+V+D   V+          G  S  +     + +D  +GI R RG+ I     
Sbjct:  19 LKASIGEDVIDISRVSAEADCFTYDPGFMSTASCQSTITYIDGDKGILRHRGYDI-----  73

Query: 113 LLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHER 172
                K   E+     + +LL+ GE+P+  Q  +  + +   + V            +ER
Sbjct:  74 -----KDLAEKSDFLEVAYLLIYGELPSSEQYNNFTKQVAHHSLV------------NER 116

Query: 173 MHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLE--------DALTLIARLPAVA 224
           +H + Q     +       MA   A     S F+   L          A+ +IA++P +A
Sbjct: 117 LHYLFQ-----TFCSSSHPMAIMLAAVGSLSAFYPDLLNFKEADYELTAIRMIAKIPTIA 171

Query: 225 ARIYRNTFHGGKHVPAEKIEKVDDM--GMRLARSLGFELNEF--DELMRLYLVLHADHEG 280
           A  Y+ +       P   ++  ++    M       +++N    + L +++ +LHADHE 
Sbjct: 172 AMSYKYSIGQPFIYPDNSLDFTENFLHMMFTTHCTKYKVNPIIKNALNKIF-ILHADHEQ 230

Query: 281 GNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTE 340
            N S   VR+ GS+ ++P+   + G+  L GP HG AN+ V    + M +++G    ++E
Sbjct: 231 -NASTSTVRIAGSSGANPFACISTGIASLWGPAHGGANEAV----INMLKEIG----SSE 281

Query: 341 NLRELCWETLREGHV--IPGFGHAVLRRTDPRYTAQREFA------LKHLPHDEMFQLVS 392
           N+ +   +   +     + GFGH V +  DPR    +E        L+ L ++ + Q+  
Sbjct: 282 NIPKYIAKAKDKNDPFRLMGFGHRVYKNYDPRAAVLKETCKEVLKELEQLENNPLLQIAI 341

Query: 393 KLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLS 448
           +L  +  +  +E    +  +PNVD +SGI+ +  G + S  +TVLF ++R +G ++
Sbjct: 342 ELEAIALK--DEYFIERKLYPNVDFYSGIIYKAMG-IPSQMFTVLFAIARTVGWMA 394


ref|NP_771479.1| citrate synthase [Bradyrhizobium japonicum USDA 110]
sp|P94325|CISY_BRAJA Citrate synthase
dbj|BAC50104.1| citrate synthase [Bradyrhizobium japonicum USDA 110]
(434 aa)

Score: 94 bits (233), Expect: 6.20644e-18
Length: 364, Idn/Pos/Gap = 99/159/47 (27%/43%/12%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQ--- 187
           +LLL G +PT +Q +     +     V  ++ R       +  HPM     +V  L    
Sbjct:  92 YLLLYGNLPTAAQKKDFDDRVIHHTMVHEQMARFFQGFRRD-AHPMAVMVASVGALAAFY 150

Query: 188 HESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVD 247
           H+S       Q    S          + +IA++P +AA  Y+ T       P   ++  +
Sbjct: 151 HDSTDINDPKQRMIAS----------MRMIAKIPTLAAMAYKYTIGQPFVYPKNSLKFAE 200

Query: 248 DMGMRLARSLGFELNEF-------DELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYL 300
           +    L         E+       D L +++ +LHADHE  N S   VR+ GS+ ++P+ 
Sbjct: 201 NF---LHMCFAVPCEEYKINPVLADALDKIF-ILHADHEQ-NASTSTVRIAGSSGANPFA 255

Query: 301 SFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFG 360
             AAG+  L GP HG AN+  L  L ++   +   P     +++   E       + GFG
Sbjct: 256 CIAAGIACLWGPAHGGANEAALAMLAEIGS-VDKIPEFIAKVKDKNSEVR-----LMGFG 309

Query: 361 HAVLRRTDPRYTAQREF---ALKHLPH--DEMFQLVSKLYEVVPRVLEEQGKV-KNPWPN 414
           H V +  DPR    ++     LK   H  D M ++  +L ++    L +Q  + +  +PN
Sbjct: 310 HRVYKNYDPRAKIMQKMCHAVLKETGHGDDPMLKVAMELEKI---ALSDQYFIDRKLYPN 366

Query: 415 VDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPKSVTTQWI 471
           VD +SGI L+  G   S F TVLF V+R +G +S   W   +  P   I RP+ + T   
Sbjct: 367 VDFYSGITLKAMGFPVSMF-TVLFAVARTVGWISQ--WSEMIEDPQQKIGRPRQLYTGVT 423

Query: 472 REHF 475
           R  +
Sbjct: 424 RRDY 427


ref|NP_360945.1| citrate synthase [EC:4.1.3.7] [Rickettsia conorii str. Malish 7]
gb|AAL03846.1| citrate synthase [EC:4.1.3.7] [Rickettsia conorii str. Malish 7]
pir||D97863 citrate (si)-synthase (EC 4.1.3.7) - Rickettsia conorii  (strain Malish 7)
sp|P51042|CISY_RICCN Citrate synthase
(435 aa)

Score: 94 bits (233), Expect: 6.63486e-18
Length: 445, Idn/Pos/Gap = 104/194/68 (23%/43%/15%)

Query:  60 VRERFGEEVLDACTVNQAYG------GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQR 112
           ++   GE+V+D   V+          G  S  +     + +D  +GI R RG+ I     
Sbjct:  26 LKASIGEDVIDISRVSAEADCFTYDPGFMSTASCQSTITYIDGDKGILRHRGYDI-----  80

Query: 113 LLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHER 172
                K   E+     + +LL+ GE+P+  Q  +  + +   + V            +ER
Sbjct:  81 -----KDLAEKSDFLEVAYLLIYGELPSGEQYNNFTKQVAHHSLV------------NER 123

Query: 173 MHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLE--------DALTLIARLPAVA 224
           +H + Q     +       MA   A     S F+   L          A+ +IA++P +A
Sbjct: 124 LHYLFQ-----TFCSSSHPMAIMLAAVGSLSAFYPDLLNFKEADYELTAIRMIAKIPTIA 178

Query: 225 ARIYRNTFHGGKHVPAEKIEKVDD-MGMRLARS-LGFELNEF--DELMRLYLVLHADHEG 280
           A  Y+ +       P   ++  ++ + M  A     + +N    + L +++ +LHADHE 
Sbjct: 179 AMSYKYSIGQPFIYPDNSLDFTENFLHMMFATPCTKYTVNPIIKNALNKIF-ILHADHEQ 237

Query: 281 GNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTE 340
            N S   VR+ GS+ ++P+   + G+  L GP HG AN+ V    + M +++G+     +
Sbjct: 238 -NASTSTVRIAGSSGANPFACISTGIASLWGPAHGGANEAV----INMIKEIGSSEYIPK 292

Query: 341 NLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFA------LKHLPHDEMFQLVSKL 394
            + +   +   +   + GFGH V +  DPR    +E        L  L ++   Q+  +L
Sbjct: 293 YIAKA--KDKNDPFRLMGFGHRVYKNYDPRAAVLKETCKEVLKELGQLDNNPFLQIAIEL 350

Query: 395 YEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDR 454
             +  +  +E    +  +PNVD +SGI+ +  G + S  +TVLF ++R +G ++   W  
Sbjct: 351 EAIALK--DEYFIERKLYPNVDFYSGIIYKAMG-IPSQMFTVLFAIARTVGWMAQ--WKE 405

Query: 455 ALGLP---IERPKSVTTQWIREHFE 476
               P   I RP+ + T ++   ++
Sbjct: 406 MHEDPEQKISRPRQLYTGYVHREYK 430


ref|YP_014187.1| citrate synthase [Listeria monocytogenes str. 4b F2365]
ref|ZP_00230881.1| citrate synthase [Listeria monocytogenes str. 4b H7858]
gb|EAL09300.1| citrate synthase [Listeria monocytogenes str. 4b H7858]
gb|AAT04364.1| citrate synthase [Listeria monocytogenes str. 4b F2365]
(373 aa)

Score: 94 bits (233), Expect: 7.33357e-18
Length: 328, Idn/Pos/Gap = 88/146/32 (26%/44%/9%)

Query: 127 EGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLL 186
           E +++LL    +P + + +   ++++   AV   ++  L    H+++HPM+     VS+L
Sbjct:  43 EEVIYLLWHLRLPNKDEFKKFKREIQENMAVSETIITSLRMQNHQKLHPMSVLRTTVSML 102

Query: 187 ---QHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKI 243
                E+++ +            E      L L A++P + A   R    G   +P    
Sbjct: 103 GVFDTEAELDDG-----------EAVYRKGLRLQAKMPTIVAAFSR-IRRGLDPIPPR-- 148

Query: 244 EKVDDMGMRLARSLGFELNEFD-ELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSF 302
           E ++     L    G E +    E M   LVLHADHE  N S    R+  + LSD Y   
Sbjct: 149 EDLNMAANFLYMITGEEADALSVEAMNKALVLHADHEF-NASTFTARVCVATLSDVYSGV 207

Query: 303 AAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHA 362
            A +  L GPLHG AN+ V   L ++ +          ++R    E +     I GFGH 
Sbjct: 208 TAAIGALKGPLHGGANERVFDMLEEIDQ--------AGDVRNYIQEKIDTKQKIMGFGHR 259

Query: 363 VLRRTDPRYTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGIL 422
           V R  DPR    RE + K        +   K +++  +V E   ++K+  PNVD +S  +
Sbjct: 260 VYRGGDPRAQHLREMSRKLTAE----KGEEKWFDISLQVEESVWELKHLKPNVDFYSASV 315

Query: 423 LRYYGLVESNFYTVLFGVSRALGTLSSL 450
               G ++ + +T++F VSR  G L+ +
Sbjct: 316 YHALG-IDRDLFTLVFSVSRVSGWLAHI 342


ref|YP_089563.1| GltA protein [Mannheimia succiniciproducens MBEL55E]
gb|AAU38978.1| GltA protein [Mannheimia succiniciproducens MBEL55E]
(427 aa)

Score: 94 bits (233), Expect: 8.03851e-18
Length: 361, Idn/Pos/Gap = 93/162/42 (25%/44%/11%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQF---SVAVSLLQ 187
           +LLL GE PT+ Q +   + +KR   V  ++ +       +  HPM      S A++   
Sbjct:  87 YLLLFGERPTKQQYQDFSKLVKRHTLVHEQLTKFFQGFRRDS-HPMAVMCGVSGALAAFY 145

Query: 188 HESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVD 247
           H+S   +            E+    A+ L+A++P +AA  Y+ +       P   +    
Sbjct: 146 HDSIDVKKE----------EHRELTAIRLLAKIPTLAAMCYKYSIGQPFMFPQNNLSYAG 195

Query: 248 D-MGMRLARSLG-FELNE-FDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAA 304
           + + M  A     + +N   +  +    +LHADHE  N S   VR+  S+ ++P+   AA
Sbjct: 196 NFLYMMFATPCEPYVVNPVLERALDKIFILHADHEQ-NASTSTVRIAASSGANPFACIAA 254

Query: 305 GLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVL 364
           G+  L GP HG AN+      + M E++G      E +     +   +   + GFGH V 
Sbjct: 255 GIASLWGPSHGGANEAC----INMLEEIGTVDRIPEFIARA--KDKNDPFRLMGFGHRVY 308

Query: 365 RRTDPRYTAQREF---ALKHLP-HDEMFQLVSKLYEVV---PRVLEEQGKVKNPWPNVDQ 417
           +  DPR    RE     LK L   + +F + S+L  +    P  ++ +      +PNVD 
Sbjct: 309 KNYDPRAKVMRETCHEVLKELNIKNPLFDVASELERIALSDPYFIDHK-----LYPNVDF 363

Query: 418 HSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRAL---GLPIERPKSVTTQWIREH 474
           +SGI+L+  G + ++ +TV+F ++R +G ++   W          I RP+ + T +    
Sbjct: 364 YSGIVLKAIG-IPTSMFTVMFALARTVGWIAH--WKEMYKQGNFKIARPRQIYTGYTERD 420

Query: 475 F 475
           F
Sbjct: 421 F 421


ref|YP_101029.1| citrate synthase [Bacteroides fragilis YCH46]
emb|CAH09229.1| putative citrate synthase [Bacteroides fragilis NCTC 9343]
ref|YP_213143.1| putative citrate synthase [Bacteroides fragilis NCTC 9343]
dbj|BAD50495.1| citrate synthase [Bacteroides fragilis YCH46]
(447 aa)

Score: 93 bits (232), Expect: 8.738e-18
Length: 363, Idn/Pos/Gap = 96/161/42 (26%/44%/11%)

Query: 102 FRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEV 161
           +RG+ + +    + + K  G     E + +LLL+G +P + ++ S  + +          
Sbjct:  72 YRGYDLEDLAHAILKEKRFGF----EEVAYLLLSGSLPDKEELASFRELIN--------- 118

Query: 162 LRLLDELPHERMHPMTQFSVAVSLLQH--ESKMAEAYA-QGAPKSTFWEYCLEDALTLIA 218
               D +P E+   M    +  + + +     + E Y     P  T  +  +  ++ LI+
Sbjct: 119 ----DNMPLEQKTKMNIIELEGNNIMNILARSVLEMYRFDPNPDDTSRDNLMRQSIDLIS 174

Query: 219 RLPAVAARIY----RNTFHGGKHV--PAEKIEKVDDMGMRLARSLGFELNEFD-ELMRLY 271
           + P + A  +      TF    H+  P E +   ++    L R    +  E D   + L 
Sbjct: 175 KFPTIIAYAFNMLRHATFGRSLHIRHPQENLSIAENFLYMLKR----DYTELDARTLDLL 230

Query: 272 LVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEK 331
           LVL A+H GGN S   VR+  S  +D Y + AAG+  L GPLHG AN +V      ++E 
Sbjct: 231 LVLQAEHGGGNNSTFTVRVTSSTGTDTYSAIAAGIGSLKGPLHGGANIQVADMFHHLQEN 290

Query: 332 LGN----RPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEM 387
           + +      + T   R L  E   +  +I G GHAV   +DPR    +E A + L H++ 
Sbjct: 291 IQDWTNVDEIDTYFTRMLNKEVYNKTGLIYGIGHAVYTISDPRAVLLKELA-RDLAHEKG 349

Query: 388 FQLVSKLYEVV-PRVLEEQGKVKNPW----PNVDQHSGILLRYYGLVESNFYTVLFGVSR 442
            +      E++  R +   GK+KN       NVD +SG +    GL +   YT LF ++R
Sbjct: 350 REREFAFLELLEERAIATFGKIKNNGKTVSSNVDFYSGFVYEMIGLPQE-IYTPLFAMAR 408

Query: 443 ALG 445
            +G
Sbjct: 409 IVG 411


gb|AAL01659.1| citrate synthase [Anaplasma centrale]
(417 aa)

Score: 93 bits (232), Expect: 9.11025e-18
Length: 323, Idn/Pos/Gap = 90/153/35 (27%/47%/10%)

Query: 132 LLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESK 191
           LLL G +P   +++     +     VP +V+ ++  LP    HPM     A+ +    + 
Sbjct:  89 LLLHGALPQGRELDDFASAVGNECHVPAQVVNVIKSLP-SSAHPM-----AILIASFVTL 142

Query: 192 MAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAE-KIEKVDDMG 250
            A  +A+ +         L+ A+  I+++P + A IYR+T  G   V A+  +  V +  
Sbjct: 143 AACYHAENSIDP------LKSAIVAISKVPGIVAAIYRHT-SGMPAVEADPNLGYVQNFV 195

Query: 251 MRLARSLGFELNE-FDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGL 309
             +   LG          +    ++HADHE  N S   VR+ GSA ++ +   +AG   L
Sbjct: 196 KMMFGDLGSTRQSVICRALESIFIMHADHEQ-NASTATVRVTGSAGANLFACLSAGAATL 254

Query: 310 AGPLHGLANQEVLRWLLQM--KEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRT 367
            GP HG AN+ V+R L ++   E++G   M  + +++      ++G  + GFGH V +  
Sbjct: 255 WGPAHGGANEAVVRMLEEIGSPERVG---MFIQRVKD-----KKDGVRLMGFGHRVYKNY 306

Query: 368 DPRYTAQREFALKHL----PHDEMFQLVSKLYEVVPRVLEEQGKVKN-PWPNVDQHSGIL 422
           DPR    R+   + L      D +  +  +L  V    L+++  VK   +PNVD +SGI+
Sbjct: 307 DPRALIIRDICKETLHELGTSDPLLDVAFELERV---ALQDEYFVKRFLYPNVDFYSGIV 363

Query: 423 LRYYGLVESNFYTVLFGVSRALG 445
           L+  G V  N +T  F ++R  G
Sbjct: 364 LKAIG-VPVNMFTAFFALARTTG 385


gb|AAM49619.1| citrate synthase [Rickettsia sp. AT1]
(410 aa)

Score: 93 bits (232), Expect: 9.41944e-18
Length: 415, Idn/Pos/Gap = 100/182/67 (24%/43%/16%)

Query:  61 RERFGEEVLDACTVNQAYG------GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQRL 113
           +   GE+V+D   V+          G  S  +     + +D  +GI R RG+ I      
Sbjct:  20 KASIGEDVIDISRVSAEADCFTYDPGFMSTASCQSTITYIDGDKGILRHRGYDI------  73

Query: 114 LPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERM 173
               K   E+     + +LL+ GE+P   Q  +  + +   + V            +ER+
Sbjct:  74 ----KDLAEKSDFLEVAYLLIYGELPNSEQYNNFTKQVAHHSLV------------NERL 117

Query: 174 HPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLE--------DALTLIARLPAVAA 225
           H + Q     +       MA   A     S F+   L          A+ +IA++P +AA
Sbjct: 118 HYLFQ-----TFCSSSHPMAIMLAAVGSLSAFYPDLLNFKEADYELTAIRMIAKIPTIAA 172

Query: 226 RIYRNTFHGGKHVPAEKIEKVDDM--GMRLARSLGFELNEF--DELMRLYLVLHADHEGG 281
             YR +       P   ++  ++    M       +++N    + L +++ +LHADHE  
Sbjct: 173 MSYRYSIGQPFIYPDNSLDFTENFLHMMFATHCTKYKVNPIIKNALNKIF-ILHADHEQ- 230

Query: 282 NVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTEN 341
           N S   VR+ GS+ ++P+   + G+  L GP HG AN+ V    + M +++G    ++EN
Sbjct: 231 NASTSTVRIAGSSGANPFACISTGIASLWGPAHGGANEAV----INMLKEIG----SSEN 282

Query: 342 LRELCWETLREGHV--IPGFGHAVLRRTDPRYTAQREFA------LKHLPHDEMFQLVSK 393
           + +   +   +     + GFGH V +  DPR    +E        L  L ++ + Q+  +
Sbjct: 283 IPKYIAKAKDKNDPFRLMGFGHRVYKNYDPRAAVLKETCKEVLKELGQLENNPLLQIAIE 342

Query: 394 LYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLS 448
           L  +  +  +E    +  +PNVD +SGI+ +  G + S  +TVLF ++R +G ++
Sbjct: 343 LEAIALK--DEYFIERKLYPNVDFYSGIIYKAMG-IPSQMFTVLFAIARTVGWMA 394


gb|AAU93059.1| citrate synthase [Methylococcus capsulatus str. Bath]
ref|YP_113343.1| citrate synthase [Methylococcus capsulatus str. Bath]
(429 aa)

Score: 93 bits (232), Expect: 1.04114e-17
Length: 410, Idn/Pos/Gap = 103/189/52 (25%/46%/12%)

Query:  73 TVNQAYGGMRSLKAMVYETSLLDPQEGI-RFRGFSIPE-CQRLLPRAKPSGEQPLPEGLL 130
           T++  YG   S  + +   + +D ++GI R+RG  I E C           E+     + 
Sbjct:  41 TLDPGYGNTGSCLSAI---TFIDGEQGILRYRGIDIAELC-----------EKSTFVEVS  86

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAV-SLLQHE 189
           +LL+ G++PT  Q     + +   + +  ++       P    HPM   S  V SL  + 
Sbjct:  87 YLLIYGQLPTVEQYARFKEKIHHHSLIHEDMKSFFTSYPGH-AHPMAILSSMVCSLSVYH 145

Query: 190 SKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDD- 248
            ++ +      P  T  E   E    L++++  +AA  Y+ +          +++ + + 
Sbjct: 146 PELLK------PDQTIDERD-ETISRLLSKVRVLAAFAYKRSVGEAFVYTRPELDYISNF 198

Query: 249 MGMRLARSL-GFELNEF-DELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGL 306
           + M   R + G+  +E   +++ +  +LHADHE  N S   VR+VGS+ ++ + + +AG+
Sbjct: 199 LHMMFTRPMRGYVPDELIRKVLDVLFILHADHEQ-NCSTSTVRMVGSSKANLFAAISAGI 257

Query: 307 NGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRR 366
             L GPLHG ANQ V+  L ++    G      E  ++       + + + GFGH V + 
Sbjct: 258 CALWGPLHGGANQAVIEMLEEIHRAGGCYKKYIERAKD-----KNDPYRLMGFGHRVYKS 312

Query: 367 TDPRYTAQREFALKHLPH----DEMFQLVSKLYEVV---PRVLEEQGKVKNPWPNVDQHS 419
            DPR    +++  + L +    D + ++   L EV    P  +E     +  +PNVD +S
Sbjct: 313 YDPRAQILKKYCDEVLNYLGIDDPILEIAKGLEEVALTDPYFIE-----RKLYPNVDFYS 367

Query: 420 GILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRAL---GLPIERPKSV 466
           GI+ R    + +N +TV+F + R  G ++   W   L   G+ I RP+ +
Sbjct: 368 GIIYRALK-IPTNMFTVMFALGRLPGWIAH--WKEMLEDPGMRIARPRQI 414


ref|YP_204201.1| citrate synthase [Vibrio fischeri ES114]
gb|AAW85313.1| citrate synthase [Vibrio fischeri ES114]
(429 aa)

Score: 93 bits (232), Expect: 1.04986e-17
Length: 350, Idn/Pos/Gap = 98/156/34 (28%/44%/9%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           ++LL GE P   + E+    + R   V  ++         +  HPM      V  L    
Sbjct:  88 YILLNGEAPNREEYETFKDIVTRHTMVHEQISSFFHGFRRD-AHPMAVMCGVVGALA--- 143

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDD-M 249
               A+   +      E+    A  L++++P ++A  Y+ +       P   +   ++ +
Sbjct: 144 ----AFYHDSLDINNDEHREIAAFRLLSKMPTLSAMSYKYSIGQPFIYPRNDLTYAENFL 199

Query: 250 GMRLARSLG-FELNEF-DELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLN 307
            M  A     +E+N      M     LHADHE  N S   VRL GS+ ++P+   AAG+ 
Sbjct: 200 HMMFANPCEEYEVNPVVARAMDKIFTLHADHEQ-NASTSTVRLAGSSGANPFACIAAGIA 258

Query: 308 GLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHV--IPGFGHAVLR 365
            L GP HG AN+  LR    M E++G    + +N+ E   +   +     + GFGH V +
Sbjct: 259 SLWGPAHGGANEACLR----MLEEIG----SVDNIDEYVAKAKDKDDPFRLMGFGHRVYK 310

Query: 366 RTDPRYTAQREF---ALKHLP-HDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGI 421
             DPR T  RE     LK L   D +  +  +L  +   + +E    K  +PNVD +SGI
Sbjct: 311 NYDPRATVMREACHDVLKELNIKDPLLDVAMELERIA--LSDEYFVSKKLYPNVDFYSGI 368

Query: 422 LLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPKSVTT 468
           +L+  G+  S F TV+F +SR +G ++   W      P   I RP+ + T
Sbjct: 369 ILKAIGIPVSMF-TVIFAMSRTVGWIAH--WSEMHSDPTNRIGRPRQLYT 415


ref|ZP_00154250.2| COG0372: Citrate synthase [Rickettsia rickettsii]
(434 aa)

Score: 93 bits (231), Expect: 1.33727e-17
Length: 436, Idn/Pos/Gap = 107/195/51 (24%/44%/11%)

Query:  60 VRERFGEEVLDACTVNQAYG------GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQR 112
           ++   GE+V+D   V+          G  S  +     + +D  +GI R RG+ I     
Sbjct:  26 LKASIGEDVIDISRVSAEADCFTYDPGFMSTASCQSTITYIDGDKGILRHRGYDI-----  80

Query: 113 LLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHER 172
                K   E+     + +LL+ GE+P+  Q  +  + +   + V  E L  L +     
Sbjct:  81 -----KDLAEKSDFLEVAYLLIYGELPSGEQYNNFTKQVAHHSLVN-ERLHYLFQTFCSS 134

Query: 173 MHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTF 232
            HPM     AV  L        A+          +Y L  A+ +IA++P +AA  Y+ + 
Sbjct: 135 SHPMAIMLAAVGSLA-------AFYPDLLNFKEADYELT-AIRMIAKIPTIAAMSYKYSI 186

Query: 233 HGGKHVPAEKIEKVDD-MGMRLARS-LGFELNEF--DELMRLYLVLHADHEGGNVSAHAV 288
                 P   ++  ++ + M  A     + +N    + L +++ +LHADHE  N S   V
Sbjct: 187 GQPFIYPDNSLDFTENFLHMMFATPCTKYTVNPIIKNALNKIF-ILHADHEQ-NASTSTV 244

Query: 289 RLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWE 348
           R+ GS+ ++P+   + G+  L GP HG AN+ V    + M +++G+     + + +   +
Sbjct: 245 RIAGSSGANPFACISTGIASLWGPAHGGANEAV----INMLKEIGSSEYIPKYIAKA--K 298

Query: 349 TLREGHVIPGFGHAVLRRTDPRYTAQREF---ALKHLPH--DEMFQLVSKLYEVVPRVLE 403
              +   + GFGH V +  DPR    +E     LK L    + + Q+  +L  +  +  +
Sbjct: 299 DKNDPFRLMGFGHRVYKNYDPRAVVLKETCKEVLKELGQLDNNLLQIAIELEAIALK--D 356

Query: 404 EQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---I 460
           E    +  +PNVD +SGI+ +  G + S  +TVLF ++R +G ++   W      P   I
Sbjct: 357 EYFIERKLYPNVDFYSGIIYKAMG-IPSQMFTVLFAIARTVGWMAQ--WKEMHEDPEQKI 413

Query: 461 ERPKSVTTQWIREHFE 476
            RP+ + T ++   ++
Sbjct: 414 SRPRQLYTGYVHREYK 429


ref|NP_470938.1| citZ [Listeria innocua Clip11262]
emb|CAC96833.1| citZ [Listeria innocua]
pir||AI1632 citrate synthase chain II homolog citZ [imported] - Listeria innocua (strain Clip11262)
(373 aa)

Score: 93 bits (230), Expect: 1.64744e-17
Length: 328, Idn/Pos/Gap = 88/145/32 (26%/44%/9%)

Query: 127 EGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLL 186
           E +++LL    +P + + +    +++   AV   ++  L    H+++HPM+     VS+L
Sbjct:  43 EEVIYLLWHLRLPNKEEFKKFKLEIQENMAVSETIITSLRMQNHQKLHPMSVLRTTVSML 102

Query: 187 ---QHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKI 243
                E+++ +            E      L L A++P + A   R    G   +P    
Sbjct: 103 GVFDTEAELDDG-----------EAVYRKGLRLQAKMPTIVAAFSR-IRRGLDPIPPR-- 148

Query: 244 EKVDDMGMRLARSLGFELNEFD-ELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSF 302
           E ++     L    G E +E   E M   LVLHADHE  N S    R+  + LSD Y   
Sbjct: 149 EDLNMAANFLYMITGEEADELSVEAMNKALVLHADHEF-NASTFTARVCVATLSDVYSGV 207

Query: 303 AAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHA 362
            + +  L GPLHG AN+ V   L ++            ++R    E +     I GFGH 
Sbjct: 208 TSAIGALKGPLHGGANERVFDMLEEID--------AAGDVRNYIQEKIDTKQKIMGFGHR 259

Query: 363 VLRRTDPRYTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGIL 422
           V R  DPR    RE + K        +   K +++  +V E   ++K+  PNVD +S  +
Sbjct: 260 VYRGGDPRAKHLREMSRKLTAE----KGEEKWFDISLQVEEAVWELKHLKPNVDFYSASV 315

Query: 423 LRYYGLVESNFYTVLFGVSRALGTLSSL 450
               G ++ + +T++F VSR  G L+ +
Sbjct: 316 YHALG-IDRDLFTLVFSVSRVSGWLAHI 342


ref|NP_070169.1| citrate synthase (citZ) [Archaeoglobus fulgidus DSM 4304]
gb|AAB89904.1| citrate synthase (citZ) [Archaeoglobus fulgidus DSM 4304]
pir||C69417 citrate synthase (citZ) homolog - Archaeoglobus fulgidus
(372 aa)

Score: 92 bits (229), Expect: 1.82093e-17
Length: 371, Idn/Pos/Gap = 101/160/43 (27%/43%/11%)

Query:  85 KAMVYETSLLDPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQV 144
           K  +   +L + +  + +RG+ I +  R     K S E+     + +LLL GE+P + ++
Sbjct:  12 KTTISRIALENGRAILEYRGYDIRDLAR-----KASYEE-----VAYLLLYGELPKKYEL  61

Query: 145 ESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKST 204
           +    +L  R  +PP+++ LL  LP    HPM     A S L    K      +      
Sbjct:  62 QDFKIELAERRELPPQIIGLLTHLP-PYTHPMVVLRTATSYLGSLDKKIAVRTR------ 114

Query: 205 FWEYCLEDALTLIARLPAVAARIYRNTFHGGKHV--PAEKIEKVDDMGMRLARSLGFELN 262
             E     A  LIA+ P + A  Y +    G+++  PA +     +    L    G E  
Sbjct: 115 --EETFNKAKDLIAKFPTIVA--YYHRIRTGRNIIPPALEFSHAANFLYMLH---GEEPT 167

Query: 263 EFDE-LMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEV 321
           +  E  + + L+LHA+HE  N S  A R+  S L+D Y    A    L GPLHG A QEV
Sbjct: 168 KTAERALDMDLILHAEHEL-NASTFAARIAASTLADIYACVVAATGTLMGPLHGGAAQEV 226

Query: 322 LRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRT-DPRYTAQREFALK 380
           +R L ++       P   E   E     +  G  I GFGH V R   DPR        L+
Sbjct: 227 MRMLREVAS-----PRRAE---EYVKRKIEAGERIMGFGHRVYRGVMDPRAE-----LLR 273

Query: 381 HLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGV 440
           +L      +  +K +E+   + +   K K   PNVD +S  +    G +  + +  +F +
Sbjct: 274 YLAKRLAAEGSTKWFEISEAIAKAAYKYKKLLPNVDFYSASVYANLG-IPDDLFVNIFAM 332

Query: 441 SRALGTLSSLV 451
            R  G  + ++
Sbjct: 333 GRISGWTAHII 343


pir||A43936 citrate (si)-synthase (EC 4.1.3.7) [validated] - Bacillus sp. (ATCC 55182)
sp|P27660|CISY_BACCO Citrate synthase
gb|AAA52231.1| citrate synthase
(373 aa)

Score: 92 bits (229), Expect: 1.88273e-17
Length: 349, Idn/Pos/Gap = 94/159/49 (26%/45%/14%)

Query: 132 LLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLL----- 186
           LLL G IP E++ + + + LK+   VP E++++L  LP +  HPM      VS+L     
Sbjct:  53 LLLEGTIPNEAEKQHLEETLKQEYDVPDEIIQVLSLLP-KTAHPMDALRTGVSVLASFDT 111

Query: 187 -----QHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAE 241
                +H + +  AY                   L+ ++P + A  Y +  H  +  P +
Sbjct: 112 ELLNREHSTNLKRAY------------------QLLGKIPNIVANSY-HILHSEE--PVQ 150

Query: 242 KIEKVDDMGMRLARSLGFELNEFDE-LMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYL 300
            ++ +      L    G +  E +E +    LVL+++HE  N S    R++ S LSD Y 
Sbjct: 151 PLQDLSYSANFLYMITGKKPTELEEKIFDRSLVLYSEHELPN-STFTARVIASTLSDLYG 209

Query: 301 SFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFG 360
           +    +  L G LHG AN+ V+  L   +        T E  + L  + L +   I GFG
Sbjct: 210 ALTGAVASLKGHLHGGANEAVMEMLQDAQ--------TVEGFKHLLHDKLSKKEKIMGFG 261

Query: 361 HAV-LRRTDPRYTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHS 419
           H V +++ DPR    +E ALK L       L+ ++ E   +++ E+   K  +PN+D ++
Sbjct: 262 HRVYMKKMDPRAAMMKE-ALKELSAVNGDDLLLQMCEAGEQIMREE---KGLFPNLDYYA 317

Query: 420 GILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLPIERPKSVTT 468
             +    G +    YT +F  SR +G L + V ++     I RP+ + T
Sbjct: 318 APVYWKLG-IPIPLYTPIFFSSRTVG-LCAHVMEQHENNRIFRPRVLYT 364


ref|NP_221192.1| CITRATE SYNTHASE  (gltA) [Rickettsia prowazekii str. Madrid E]
emb|CAA15268.1| CITRATE SYNTHASE (gltA) [Rickettsia prowazekii]
pir||YKRECP citrate (si)-synthase (EC 4.1.3.7) - Rickettsia prowazekii
sp|P09948|CISY_RICPR Citrate synthase
gb|AAA26383.1| citrate synthase
(436 aa)

Score: 92 bits (229), Expect: 1.93045e-17
Length: 369, Idn/Pos/Gap = 92/170/55 (24%/46%/14%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +L++ GE+P+  Q    C   K+ A            L +ER+H + Q     +      
Sbjct:  94 YLMIYGELPSSDQY---CNFTKKVAH---------HSLVNERLHYLFQ-----TFCSSSH 136

Query: 191 KMAEAYAQGAPKSTFWEYCLE--------DALTLIARLPAVAARIYRNTFHGGKHVPAEK 242
            MA   A     S F+   L          A+ +IA++P +AA  Y+ +       P   
Sbjct: 137 PMAIMLAAVGSLSAFYPDLLNFNETDYELTAIRMIAKIPTIAAMSYKYSIGQPFIYPDNS 196

Query: 243 IEKVDD-MGMRLARS-LGFELNEF--DELMRLYLVLHADHEGGNVSAHAVRLVGSALSDP 298
           ++  ++ + M  A     +++N    + L +++ +LHADHE  N S   VR+ GS+ ++P
Sbjct: 197 LDFTENFLHMMFATPCTKYKVNPIIKNALNKIF-ILHADHEQ-NASTSTVRIAGSSGANP 254

Query: 299 YLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHV--I 356
           +   + G+  L GP HG AN+ V    + M +++G    ++EN+ +   +   +     +
Sbjct: 255 FACISTGIASLWGPAHGGANEAV----INMLKEIG----SSENIPKYVAKAKDKNDPFRL 306

Query: 357 PGFGHAVLRRTDPRYTAQREFA------LKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKN 410
            GFGH V +  DPR    +E        L  L ++ + Q+  +L  +  +  +E    + 
Sbjct: 307 MGFGHRVYKSYDPRAAVLKETCKEVLNELGQLDNNPLLQIAIELEALALK--DEYFIERK 364

Query: 411 PWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPKSVT 467
            +PNVD +SGI+ +  G + S  +TVLF ++R +G ++   W      P   I RP+ + 
Sbjct: 365 LYPNVDFYSGIIYKAMG-IPSQMFTVLFAIARTVGWMAQ--WKEMHEDPEQKISRPRQLY 421

Query: 468 TQWIREHFE 476
           T ++   ++
Sbjct: 422 TGYVHREYK 430


gb|AAB02952.1| citrate synthase [Israeli tick typhus rickettsia]
(411 aa)

Score: 92 bits (229), Expect: 1.94662e-17
Length: 433, Idn/Pos/Gap = 104/191/68 (24%/44%/15%)

Query:  60 VRERFGEEVLDACTVNQAYG------GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQR 112
           ++   GE+V+D   V+          G  S  +     + +D  +GI R+RG+ I     
Sbjct:  19 LKASIGEDVIDISRVSAEADCFTYDPGFMSTASCQSTITYIDGDKGILRYRGYDI-----  73

Query: 113 LLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHER 172
                K   E+     + +LL+ GE+P+  Q  +  + +   + V            +ER
Sbjct:  74 -----KDLAEKSDFLEVAYLLIYGELPSGEQYNNFTKQVAHHSLV------------NER 116

Query: 173 MHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLE--------DALTLIARLPAVA 224
           +H + Q     +       MA   A     S F+   L          A+ +IA++P +A
Sbjct: 117 LHYLFQ-----TFCSSSHPMAIMLAAVGSLSAFYPDLLNFKEADYELTAIRMIAKIPTIA 171

Query: 225 ARIYRNTFHGGKHVPAEKIEKVDD-MGMRLARS-LGFELNEF--DELMRLYLVLHADHEG 280
           A  Y+ +       P   ++  ++ + M  A     + +N    + L +++ +LHADHE 
Sbjct: 172 AMSYKYSIGQPFIYPDNSLDFTENFLHMMFATPCTKYTVNPIIKNALNKIF-ILHADHEQ 230

Query: 281 GNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTE 340
            N S   VR+ GS+ ++P+   + G+  L GP HG AN+ V    + M +++G+     +
Sbjct: 231 -NASTSTVRIAGSSGANPFACISTGIASLWGPAHGGANEAV----INMLKEIGSSEYIPK 285

Query: 341 NLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREF------ALKHLPHDEMFQLVSKL 394
            + +   +   +   + GFGH V +  DPR    +E       AL  L ++ + Q+  +L
Sbjct: 286 YIAKA--KDKNDPFRLMGFGHRVYKNYDPRAAVLKETCKEVLKALGQLDNNPLLQIAIEL 343

Query: 395 YEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDR 454
             +  +  +E    +  +PNVD +SGI+ +  G + S  +TVLF ++R +G ++   W  
Sbjct: 344 EAIALK--DEYFIERKLYPNVDFYSGIIYKAMG-IPSQMFTVLFVIARIVGWMAQ--WKE 398

Query: 455 ALGLP---IERPK 464
               P   I RP+
Sbjct: 399 MHEDPEQKISRPR 411


gb|AAO50962.1| similar to Dictyostelium discoideum (Slime mold). Citrate synthase
gb|EAL68984.1| citrate synthase [Dictyostelium discoideum]
(512 aa)

Score: 92 bits (229), Expect: 1.99597e-17
Length: 350, Idn/Pos/Gap = 90/152/34 (25%/43%/9%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LL+ G++P++ Q       +     +   ++ ++    ++  HPM     ++S +    
Sbjct: 104 YLLIYGDLPSKEQSNLWNTKIMNHTFIHENLISMMKSFRYD-AHPMGMLISSLSAMSTFY 162

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMG 250
             A     G       +   +    ++ +LP +AA  YR+      + P+  +   ++  
Sbjct: 163 PEANPALAGVDIYKNKQLMNKQIFRILGKLPTIAACAYRHRIGRPYNDPSNTLSYTENFL 222

Query: 251 MRLARSLGFELNEFDELMRLY---LVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLN 307
             L R           L R      ++HADHE  N S   +R + S L DPY + A    
Sbjct: 223 YMLDRLSESNYKPHPVLTRALDKLFIIHADHEL-NCSTATMRQIASTLVDPYTACAGSAG 281

Query: 308 GLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRT 367
            L GPLHG AN+ VLR    M E +G    T EN+ +   +  ++   + GFGH V +  
Sbjct: 282 ALYGPLHGGANEAVLR----MLEAIG----TIENIPKFIEQVKQKKQRLMGFGHRVYKSY 333

Query: 368 DPRYTAQRE-----FALKHLPHDEMFQLVSKLYEVV---PRVLEEQGKVKNPWPNVDQHS 419
           DPR    +      FAL  L  + + Q+ ++L  +       +E Q      +PNVD +S
Sbjct: 334 DPRAKILKTVTMEIFAL--LGKNPLMQIATELERLALSDSYFIERQ-----LYPNVDFYS 386

Query: 420 GILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPKSV 466
           GI+ +  G   ++ + VLF + RA G L+   W   L  P   I RP+ +
Sbjct: 387 GIIYKSMGF-PTDMFPVLFSIPRAAGWLAH--WVEELADPELRIFRPRQI 433


gb|AAF89755.1| citrate synthase [Rickettsia sp. HL-93]
(412 aa)

Score: 92 bits (229), Expect: 2.01269e-17
Length: 437, Idn/Pos/Gap = 104/191/68 (23%/43%/15%)

Query:  60 VRERFGEEVLDACTVNQAYG------GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQR 112
           ++   GE+V+D   V+          G  S  +     + +D  +GI R RG+ I     
Sbjct:  14 LKASIGEDVIDISRVSAEADCFTYDPGFMSTASCQSTITYIDGDKGILRHRGYDI-----  68

Query: 113 LLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHER 172
                K   E+     + +LL+ GE+P+  Q  +  + +   + V            +ER
Sbjct:  69 -----KDLAEKSDFLEVAYLLIYGELPSGEQYNNFTKQVAHHSLV------------NER 111

Query: 173 MHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLE--------DALTLIARLPAVA 224
           +H + Q     +       MA   A     S F+   L          A+ +IA++P +A
Sbjct: 112 LHYLFQ-----TFCSSSHPMAIMLAAVGSLSAFYPDLLNFKEADYELTAIRMIAKIPTIA 166

Query: 225 ARIYRNTFHGGKHVPAEKIEKVDD-MGMRLARSL-GFELNEF--DELMRLYLVLHADHEG 280
           A  Y+ +       P   ++  ++ + M  A     + +N    + L +++ +LHADHE 
Sbjct: 167 AMSYKYSIGQPFIYPDNSLDFTENFLHMMFATPYTKYTVNPIIKNALNKIF-ILHADHEQ 225

Query: 281 GNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTE 340
            N S   VR+ GS+ ++P+   + G+  L GP HG AN+ V    + M +++G+     +
Sbjct: 226 -NASTSTVRIAGSSGANPFACISTGIASLWGPAHGGANEAV----INMLKEIGSSEYIPK 280

Query: 341 NLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFA------LKHLPHDEMFQLVSKL 394
            + +   +   +   + GFGH V +  DPR    +E        L  L ++ + Q+  +L
Sbjct: 281 YIAKA--KDKNDPFRLMGFGHRVYKNYDPRAAVLKETCKEVLKELGQLDNNPLLQIAIEL 338

Query: 395 YEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDR 454
             +  +  +E    +  +PNVD +SGI+ +  G + S  +TVLF ++R +G ++   W  
Sbjct: 339 EAIALK--DEYFIERKLYPNVDFYSGIIYKAMG-IPSQMFTVLFAIARTVGWMAQ--WKE 393

Query: 455 ALGLP---IERPKSVTT 468
               P   I RP+ + T
Sbjct: 394 MHEDPEQKISRPRQLYT 410


gb|AAP35265.1| citrate synthase [Rickettsia heilongjiangensis]
(416 aa)

Score: 92 bits (229), Expect: 2.01269e-17
Length: 437, Idn/Pos/Gap = 104/191/68 (23%/43%/15%)

Query:  60 VRERFGEEVLDACTVNQAYG------GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQR 112
           ++   GE+V+D   V+          G  S  +     + +D  +GI R RG+ I     
Sbjct:  19 LKASIGEDVIDISRVSAEADCFTYDPGFMSTASCQSTITYIDGDKGILRHRGYDI-----  73

Query: 113 LLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHER 172
                K   E+     + +LL+ GE+P+  Q  +  + +   + V            +ER
Sbjct:  74 -----KDLAEKSDFLEVAYLLIYGELPSGEQYNNFTKQVAHHSLV------------NER 116

Query: 173 MHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLE--------DALTLIARLPAVA 224
           +H + Q     +       MA   A     S F+   L          A+ +IA++P +A
Sbjct: 117 LHYLFQ-----TFCSSSHPMAIMLAAVGSLSAFYPDLLNFKEADYELTAIRMIAKIPTIA 171

Query: 225 ARIYRNTFHGGKHVPAEKIEKVDD-MGMRLARSL-GFELNEF--DELMRLYLVLHADHEG 280
           A  Y+ +       P   ++  ++ + M  A     + +N    + L +++ +LHADHE 
Sbjct: 172 AMSYKYSIGQPFIYPDNSLDFTENFLHMMFATPYTKYTVNPIIKNALNKIF-ILHADHEQ 230

Query: 281 GNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTE 340
            N S   VR+ GS+ ++P+   + G+  L GP HG AN+ V    + M +++G+     +
Sbjct: 231 -NASTSTVRIAGSSGANPFACISTGIASLWGPAHGGANEAV----INMLKEIGSSEYIPK 285

Query: 341 NLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFA------LKHLPHDEMFQLVSKL 394
            + +   +   +   + GFGH V +  DPR    +E        L  L ++ + Q+  +L
Sbjct: 286 YIAKA--KDKNDPFRLMGFGHRVYKNYDPRAAVLKETCKEVLKELGQLDNNPLLQIAIEL 343

Query: 395 YEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDR 454
             +  +  +E    +  +PNVD +SGI+ +  G + S  +TVLF ++R +G ++   W  
Sbjct: 344 EAIALK--DEYFIERKLYPNVDFYSGIIYKAMG-IPSQMFTVLFAIARTVGWMAQ--WKE 398

Query: 455 ALGLP---IERPKSVTT 468
               P   I RP+ + T
Sbjct: 399 MHEDPEQKISRPRQLYT 415


gb|AAG43416.2| citrate synthase [Rickettsia heilongjiangii]
(413 aa)

Score: 92 bits (229), Expect: 2.01269e-17
Length: 437, Idn/Pos/Gap = 104/191/68 (23%/43%/15%)

Query:  60 VRERFGEEVLDACTVNQAYG------GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQR 112
           ++   GE+V+D   V+          G  S  +     + +D  +GI R RG+ I     
Sbjct:  16 LKASIGEDVIDISRVSAEADCFTYDPGFMSTASCQSTITYIDGDKGILRHRGYDI-----  70

Query: 113 LLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHER 172
                K   E+     + +LL+ GE+P+  Q  +  + +   + V            +ER
Sbjct:  71 -----KDLAEKSDFLEVAYLLIYGELPSGEQYNNFTKQVAHHSLV------------NER 113

Query: 173 MHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLE--------DALTLIARLPAVA 224
           +H + Q     +       MA   A     S F+   L          A+ +IA++P +A
Sbjct: 114 LHYLFQ-----TFCSSSHPMAIMLAAVGSLSAFYPDLLNFKEADYELTAIRMIAKIPTIA 168

Query: 225 ARIYRNTFHGGKHVPAEKIEKVDD-MGMRLARSL-GFELNEF--DELMRLYLVLHADHEG 280
           A  Y+ +       P   ++  ++ + M  A     + +N    + L +++ +LHADHE 
Sbjct: 169 AMSYKYSIGQPFIYPDNSLDFTENFLHMMFATPYTKYTVNPIIKNALNKIF-ILHADHEQ 227

Query: 281 GNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTE 340
            N S   VR+ GS+ ++P+   + G+  L GP HG AN+ V    + M +++G+     +
Sbjct: 228 -NASTSTVRIAGSSGANPFACISTGIASLWGPAHGGANEAV----INMLKEIGSSEYIPK 282

Query: 341 NLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFA------LKHLPHDEMFQLVSKL 394
            + +   +   +   + GFGH V +  DPR    +E        L  L ++ + Q+  +L
Sbjct: 283 YIAKA--KDKNDPFRLMGFGHRVYKNYDPRAAVLKETCKEVLKELGQLDNNPLLQIAIEL 340

Query: 395 YEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDR 454
             +  +  +E    +  +PNVD +SGI+ +  G + S  +TVLF ++R +G ++   W  
Sbjct: 341 EAIALK--DEYFIERKLYPNVDFYSGIIYKAMG-IPSQMFTVLFAIARTVGWMAQ--WKE 395

Query: 455 ALGLP---IERPKSVTT 468
               P   I RP+ + T
Sbjct: 396 MHEDPEQKISRPRQLYT 412


gb|AAG43417.1| citrate synthase [Rickettsia sp. BJ-90]
(413 aa)

Score: 92 bits (229), Expect: 2.09843e-17
Length: 437, Idn/Pos/Gap = 104/191/68 (23%/43%/15%)

Query:  60 VRERFGEEVLDACTVNQAYG------GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQR 112
           ++   GE+V+D   V+          G  S  +     + +D  +GI R RG+ I     
Sbjct:  16 LKASIGEDVIDISRVSAEADCFTYDPGFMSTASCQSTITYIDGDKGILRHRGYDI-----  70

Query: 113 LLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHER 172
                K   E+     + +LL+ GE+P+  Q  +  + +   + V            +ER
Sbjct:  71 -----KDLAEKSDFLEVAYLLIYGELPSGEQYNNFTKQVAHHSLV------------NER 113

Query: 173 MHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLE--------DALTLIARLPAVA 224
           +H + Q     +       MA   A     S F+   L          A+ +IA++P +A
Sbjct: 114 LHYLFQ-----TFCSSSHPMAIMLAAVGSLSAFYPDLLNFKEADYELTAIRMIAKIPTIA 168

Query: 225 ARIYRNTFHGGKHVPAEKIEKVDD-MGMRLARS-LGFELNEF--DELMRLYLVLHADHEG 280
           A  Y+ +       P   ++  ++ + M  A     + +N    + L +++ +LHADHE 
Sbjct: 169 AMSYKYSIGQPFIYPDNSLDFTENFLHMMFATPCTKYTVNPIIKNALNKIF-ILHADHEQ 227

Query: 281 GNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTE 340
            N S   VR+ GS+ ++P+   + G+  L GP HG AN+ V    + M +++G+     +
Sbjct: 228 -NASTSTVRIAGSSGANPFACISTGIASLWGPAHGGANEAV----INMLKEIGSSEYIPK 282

Query: 341 NLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFA------LKHLPHDEMFQLVSKL 394
            + +   +   +   + GFGH V +  DPR    +E        L  L ++ + Q+  +L
Sbjct: 283 YIAKA--KDKNDPFRLMGFGHRVYKNYDPRAAVLKETCKEVLKELGQLDNNPLLQIAIEL 340

Query: 395 YEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDR 454
             +  +  +E    +  +PNVD +SGI+ +  G + S  +TVLF ++R +G ++   W  
Sbjct: 341 EAIALK--DEYFIERKLYPNVDFYSGIIYKAMG-IPSQMFTVLFAIARTVGWMAQ--WKE 395

Query: 455 ALGLP---IERPKSVTT 468
               P   I RP+ + T
Sbjct: 396 MHEDPEQKISRPRQLYT 412


gb|AAS88992.1| citrate-synthase [Candidatus Rickettsia principis]
(416 aa)

Score: 92 bits (229), Expect: 2.18783e-17
Length: 359, Idn/Pos/Gap = 88/162/51 (24%/45%/14%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LL+ GE+P+  Q  +  + +   + V            HER+H + Q     +      
Sbjct:  87 YLLIYGELPSSEQYNNFTKQVAHHSLV------------HERLHYLFQ-----TFCNSSH 129

Query: 191 KMAEAYAQGAPKSTFWEYCLE--------DALTLIARLPAVAARIYRNTFHGGKHVPAEK 242
            MA   A     S F+   L          A+ +IA++P +A   Y+ +       P   
Sbjct: 130 PMAMMLAAVGSLSAFYPDLLNFKDADYELTAIRMIAKIPTIATMSYKYSIGQPFIYPDNS 189

Query: 243 IEKVDD-MGMRLARS-LGFELNEF--DELMRLYLVLHADHEGGNVSAHAVRLVGSALSDP 298
           ++  ++ + M  A     F++N    + L +++ +LHADHE  N S   VR+ GS+ ++P
Sbjct: 190 LDFTENFLHMMFAMPCTKFKVNPIIKNALNKIF-ILHADHEQ-NASTSTVRIAGSSGANP 247

Query: 299 YLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPG 358
           +   + G+  L GP HG AN+ V    + M +++G+     + + +   +   +   + G
Sbjct: 248 FACISTGIASLWGPAHGGANEAV----INMLKEIGSSEYIPKYIAKA--KDKNDPFRLMG 301

Query: 359 FGHAVLRRTDPRYTAQREFA------LKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPW 412
           FGH V +  DPR    +E        L  L ++ + Q+  +L  +  +  +E    +  +
Sbjct: 302 FGHRVYKNYDPRAAVLKETCKEVLKELGQLDNNPLLQIAIELEAIALK--DEYFIERKLY 359

Query: 413 PNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPKSVTT 468
           PNVD +SGI+    G + +  +TVLF ++R +G ++   W      P   I RP+ + T
Sbjct: 360 PNVDFYSGIIYNAMG-IPTQMFTVLFAIARTVGWMAQ--WKEMHEDPEQKISRPRQLYT 415


gb|AAB02951.1| citrate synthase [Rickettsia sp. A-167]
sp|Q59136|CISY_ASTRI Citrate synthase
(411 aa)

Score: 92 bits (229), Expect: 2.18783e-17
Length: 433, Idn/Pos/Gap = 104/190/68 (24%/43%/15%)

Query:  60 VRERFGEEVLDACTVNQAYG------GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQR 112
           ++   GE+V+D   V+          G  S  +     + +D  +GI R RG+ I     
Sbjct:  19 LKASIGEDVIDISRVSAEADCFTYDPGFMSTASCQSTITYIDGDKGILRHRGYDI-----  73

Query: 113 LLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHER 172
                K   E+     + +LL+ GE+P+  Q  +  + +   + V            +ER
Sbjct:  74 -----KDLAEKSDFLEVAYLLIYGELPSGEQYNNFTKQVAHHSLV------------NER 116

Query: 173 MHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLE--------DALTLIARLPAVA 224
           +H + Q     +       MA   A     S F+   L          A+ +IA++P +A
Sbjct: 117 LHYLFQ-----TFCSSSHPMAIMLAAVGSLSAFYPDLLNFKEADYELTAIRMIAKIPTIA 171

Query: 225 ARIYRNTFHGGKHVPAEKIEKVDD-MGMRLARS-LGFELNEF--DELMRLYLVLHADHEG 280
           A  Y+ +       P   ++  ++ + M  A     + +N    + L +++ +LHADHE 
Sbjct: 172 AMSYKYSIGQPFIYPDNPLDFTENFLHMMFATPCTKYTVNPIIKNALNKIF-ILHADHEQ 230

Query: 281 GNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTE 340
            N S   VR+ GS+ ++P+   + G+  L GP HG AN+ V    + M +++G+     +
Sbjct: 231 -NASTSTVRIAGSSGANPFACISTGIASLWGPAHGGANEAV----INMLKEIGSSEYIPK 285

Query: 341 NLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREF------ALKHLPHDEMFQLVSKL 394
            + +   +   +   + GFGH V +  DPR    +E       AL  L ++ + Q+  +L
Sbjct: 286 YIAKA--KDKNDPFRLMGFGHRVYKNYDPRAAVLKETCKEVLKALGQLDNNPLLQIAIEL 343

Query: 395 YEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDR 454
             +  +  +E    +  +PNVD +SGI+ +  G + S  +TVLF ++R +G ++   W  
Sbjct: 344 EAIALK--DEYFIERKLYPNVDFYSGIIYKAMG-IPSQMFTVLFAIARTVGWMAQ--WKE 398

Query: 455 ALGLP---IERPK 464
               P   I RP+
Sbjct: 399 MHEDPEQKISRPR 411


gb|AAG48553.1| citrate synthase [Rickettsia sp. California 2]
(404 aa)

Score: 92 bits (228), Expect: 2.60681e-17
Length: 435, Idn/Pos/Gap = 105/192/72 (24%/44%/16%)

Query:  60 VRERFGEEVLDACTVNQAYG------GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQR 112
           ++   GE+V+D   V+          G  S  +     + +D  +GI R RG+ I     
Sbjct:  12 LKASIGEDVIDISRVSSEADCFTYDPGFMSTASCQSTITYIDGDKGILRHRGYDI-----  66

Query: 113 LLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHER 172
                K   E+     + +LL+ GE+P+  Q  +  + +   + V            +ER
Sbjct:  67 -----KDLAEKSDFLEVAYLLIYGELPSIEQYNNFTKQVAHHSLV------------NER 109

Query: 173 MHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLE--------DALTLIARLPAVA 224
           +H + Q     +       MA   A     S F+   L          A+ +IA++P +A
Sbjct: 110 LHYLFQ-----TFCSSSHPMAIMLAAVGSLSAFYPDLLNFKEADYELTAIRMIAKIPTIA 164

Query: 225 ARIYRNTFHGGKHVPAEKIEKVDD-MGMRLARS-LGFELNEF--DELMRLYLVLHADHEG 280
           A  Y+ +       P   ++  ++ + M  A     +++N    + L +++ +LHADHE 
Sbjct: 165 AMSYKYSIGQPFIYPDNSLDFTENFLHMMFATPCTKYKVNPIIKNALNKIF-ILHADHEQ 223

Query: 281 GNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTE 340
            N S   VR+ GS+ ++P+   + G+  L GP HG AN+ V    + M +++G    ++E
Sbjct: 224 -NASTSTVRIAGSSGANPFACVSTGIASLWGPAHGGANEAV----INMLKEIG----SSE 274

Query: 341 NLRELCWETLREGHV--IPGFGHAVLRRTDPRYTAQREFA------LKHLPHDEMFQLVS 392
           N+ +   +   +     + GFGH V +  DPR    +E        L  L ++ + Q+  
Sbjct: 275 NIPKYIAKAKDKNDPFRLMGFGHRVYKNYDPRAAVLKETCKEVLKELGQLENNPLLQIAI 334

Query: 393 KLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVW 452
           +L  +  +  +E    +  +PNVD +SGI+ +  G + S  +TVLF ++R +G ++   W
Sbjct: 335 ELEAIALK--DEYFIERKLYPNVDFYSGIIYKAMG-IPSQMFTVLFAIARTVGWMAQ--W 389

Query: 453 DRALGLP---IERPK 464
                 P   I RP+
Sbjct: 390 KEMHEDPEQKISRPR 404


emb|CAD10743.1| citrate synthase [Thermus aquaticus]
(377 aa)

Score: 92 bits (228), Expect: 2.60681e-17
Length: 333, Idn/Pos/Gap = 101/144/38 (30%/43%/11%)

Query: 121 GEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFS 180
            E+   E   +LLL G +P   ++E+  +DL  R A+P  +L      P    HPM+   
Sbjct:  38 AEKSTFEETTYLLLHGRLPQRGELEAFKKDLAARRALPSHLLESFRRYP-ASAHPMSFLR  96

Query: 181 VAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPA 240
            AVS    E  M +       +   ++      L LIA+   + A   R     GK  P 
Sbjct:  97 TAVS----ELGMLDPTEGDISREALYQ----KGLDLIAKFATIVAANKR--LKEGKE-PL 145

Query: 241 EKIEKVDDMGMRLARSLGFELN-EFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPY 299
              E +      L  + G E + E + LM   L+LHA+H G N S        S  +D Y
Sbjct: 146 PPREDLSHAANFLYMANGVEPSPEQERLMDAALILHAEH-GFNASTFTAIAAFSTETDLY 204

Query: 300 LSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGF 359
            +  A +  L GP HG AN+ V++    M +++G      E  RE   E L +   I G 
Sbjct: 205 SAITAAVASLKGPRHGGANEAVMK----MIQEIG----APERAREWVREKLSKKERIMGM 256

Query: 360 GHAVLRRTDPRYTA----QREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNP---W 412
           GH V +  DPR        R  A KH    E        Y+++  V EE GKV NP   +
Sbjct: 257 GHRVYKAFDPRAGVLEKLARRVAEKHGHSPE--------YQILKIVEEEAGKVLNPRGIY 308

Query: 413 PNVDQHSGILLRYYGLVESNFYTVLFGVSRALG 445
           PNVD +SG++    G     F+T +F V+R  G
Sbjct: 309 PNVDFYSGVVYSDLGF-GLEFFTPIFAVARISG 340


gb|AAN77499.1| citrate synthase [Sinorhizobium fredii]
(429 aa)

Score: 92 bits (227), Expect: 3.70086e-17
Length: 350, Idn/Pos/Gap = 92/160/37 (26%/45%/10%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LLL GE+PT++Q +     +     +  ++ R       +  HPM      V  L    
Sbjct:  88 YLLLYGELPTKAQKDDFDYRVTHHTMIHEQMSRFFTGFRRD-AHPMAVMCGCVGALS--- 143

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHV--PAEKIEKVDD 248
               A+   +   T     +  +L +IA++P +AA  Y+  +H G+    P   ++   +
Sbjct: 144 ----AFYHDSTDITDPHQRMVASLRMIAKMPTIAAMAYK--YHIGQPFIYPKNDLDYASN 197

Query: 249 MGMRLARSLGFE---LNE-FDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAA 304
             +R+  ++  E   +N      M    +LHADHE  N S   VRL GS+ ++P+   AA
Sbjct: 198 F-LRMCFAVPCEDYVVNPVLSRAMDRIFILHADHEQ-NASTSTVRLAGSSGANPFACIAA 255

Query: 305 GLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVL 364
           G+  L GP HG AN+      L M  ++G+     E +     +   +   + GFGH V 
Sbjct: 256 GIACLWGPAHGGANEAA----LNMLAEIGSVDRIPEFITRA--KDKNDPFRLMGFGHRVY 309

Query: 365 RRTDPRYTAQREFA---LKHLPH--DEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHS 419
           +  DPR    ++     L  L H  D + ++  +L  +   + +E    K  +PN+D +S
Sbjct: 310 KNYDPRAKIMQKTTHEVLAELGHKDDPLLEVAMELERIA--LTDEYFIEKKLYPNIDFYS 367

Query: 420 GILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPKSV 466
           GI L+  G   +  +TVLF ++R +G ++   W+  +  P   I RP+ +
Sbjct: 368 GITLKALGF-PTTMFTVLFALARTVGWIAQ--WNEMIEDPEQRIGRPRQL 414


ref|ZP_00335656.1| COG0372: Citrate synthase [Thiobacillus denitrificans ATCC 25259]
(431 aa)

Score: 91 bits (226), Expect: 4.12487e-17
Length: 362, Idn/Pos/Gap = 100/161/43 (27%/44%/11%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LLL GE+PT  Q     Q ++    +  ++  +         HPM        ++    
Sbjct:  88 YLLLHGELPTAEQKAGFEQSIRHHTLLHDQIENVFRGF-RRSAHPMA------VMIGVTG 140

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHV--PAEKIEKVDD 248
            M+  Y  G       E+    A  LIA++P VAA  Y+  F+ G+    P  ++   ++
Sbjct: 141 AMSAFYHAGLDNFNP-EHREIVAHRLIAKIPTVAAWAYK--FNEGQPFVYPQNRLSYAEN 197

Query: 249 MGMRLARSLGFELNEFDELMRLY---LVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAG 305
               +  S   E      L R      +LHADHE  N S   VRL GS+ ++PY   A+G
Sbjct: 198 FMYMMFSSPCEEYVPNPVLARALDRIFILHADHEQ-NASTSTVRLAGSSGANPYACIASG 256

Query: 306 LNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLR 365
           +  L GPLHG AN+ VLR    M E++ +     + ++    +   +   + GFGH V +
Sbjct: 257 MASLWGPLHGGANEAVLR----MLEEIDDASKIPDFIKRA--KDKSDPFRLMGFGHRVYK 310

Query: 366 RTDPR--------YTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNP-WPNVD 416
             DPR        Y    E  L+    D  F++  +L  +    LE++  ++   +PNVD
Sbjct: 311 NMDPRAAIIRRTCYEVLDELGLR---DDPQFKIALELERI---ALEDEYFIERKLYPNVD 364

Query: 417 QHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPKSVTTQWIRE 473
            +SGI+ R  G + ++ +T LF ++R  G ++   W   L  P   I RP+ +     R 
Sbjct: 365 FYSGIIFRAMG-IPTSMFTALFAMARTAGWVAQ--WHEMLSDPAHKIGRPRQLYAGPARR 421

Query: 474 HF 475
            F
Sbjct: 422 DF 423


ref|ZP_00151189.2| COG0372: Citrate synthase [Dechloromonas aromatica RCB]
(432 aa)

Score: 91 bits (226), Expect: 5.08161e-17
Length: 353, Idn/Pos/Gap = 90/153/43 (25%/43%/12%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LL  GE+P   Q       +K    V  ++ +       +  HPM   +  V  L    
Sbjct:  90 YLLKNGELPNAKQKADFESTIKNHTMVHEQLSKFFSGFRRD-AHPMAVMTGVVGALSAFY 148

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMG 250
             A  ++    ++  +         L+A++P + A  Y+         P   ++   +  
Sbjct: 149 HDAMDFSDAEHRNVSFN-------RLVAKMPTIVAMAYKYNTGAPFMYPDNSLDYTANF- 200

Query: 251 MRLARSLGFELNEF---DELMRLY---LVLHADHEGGNVSAHAVRLVGSALSDPYLSFAA 304
           MR+    G    ++     L+R       LHADHE  N S   VRL GS+ ++P+   AA
Sbjct: 201 MRMM--FGNPCEKYVPNPVLVRALDTIFTLHADHEQ-NASTSTVRLAGSSGANPFACIAA 257

Query: 305 GLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVL 364
           G+  L GP HG AN+      LQM E++G+     E +     +   +   + GFGH V 
Sbjct: 258 GIACLWGPAHGGANEAC----LQMLEEIGDVSRVPEYIARA--KDKNDSFKLMGFGHRVY 311

Query: 365 RRTDPRYTAQRE-----FALKHLPHDEMFQLVSKLYEVV---PRVLEEQGKVKNPWPNVD 416
           +  DPR    R+      A   L +D +F+L  +L  +    P  +E     K  +PNVD
Sbjct: 312 KNFDPRAKLMRQVCNEVLAELGLENDRLFKLAMELERIALEDPYFVE-----KKLYPNVD 366

Query: 417 QHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPKSV 466
            +SGI+ +  G + +  +T +F ++R +G ++   W+  +  P   I RP+ +
Sbjct: 367 FYSGIVQKAIG-IPTEMFTCIFALARTVGWMTQ--WEEMISDPEYKIGRPRQL 416


ref|NP_744484.1| methylcitrate synthase, putative [Pseudomonas putida KT2440]
gb|AAN67948.1| methylcitrate synthase, putative [Pseudomonas putida KT2440]
(375 aa)

Score: 91 bits (226), Expect: 5.08161e-17
Length: 331, Idn/Pos/Gap = 91/152/31 (27%/45%/9%)

Query: 127 EGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLL 186
           E + +LLL GE+PT++++    + LK    +P  +  +L+ +P +  HPM       S+L
Sbjct:  49 EEVAYLLLYGELPTQAELADYKRKLKGLRDLPQALKEVLERIPRD-AHPMDVMRTGCSVL 107

Query: 187 QHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKV 246
                         P+ TF E   +    L+A  PAV    YR T HG   V  +     
Sbjct: 108 ----------GTLEPELTF-EAQRDKTDRLLALFPAVMCYWYRFTHHG---VRIDCTTDE 153

Query: 247 DDMGMRLARSL-GFELNEFD-ELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAA 304
           D +G      L G + +E   ++M + L+L+A+HE  N S    R+  S LSD Y    A
Sbjct: 154 DTLGGHFLHLLHGKKPSELHVKVMNVSLILYAEHEF-NASTFTARVCASTLSDLYSCVTA 212

Query: 305 GLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVL 364
            +  L GPLHG AN+  +  + + +     +  T E LR      L     I GFGHA+ 
Sbjct: 213 AIGSLRGPLHGGANEAAMELIERFQSP---QEATAELLR-----MLERKDKIMGFGHAIY 264

Query: 365 RRTDPRYTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLR 424
           + +DPR    + ++ K L  +   +++  + E + + + EQ ++   +PN D +      
Sbjct: 265 KESDPRNEVIKGWS-KQLADEVGDKVLYPVSEAIDKTMWEQKRL---FPNADFYHASAYH 320

Query: 425 YYGLVESNFYTVLFGVSRALGTLSSLVWDRA 455
           + G + +  +T +F  SR  G  + +   RA
Sbjct: 321 FMG-IPTKLFTPIFVCSRLTGWAAHVFEQRA 350


gb|AAB02970.1| citrate synthase [Rickettsia sp.]
(411 aa)

Score: 91 bits (225), Expect: 5.29809e-17
Length: 425, Idn/Pos/Gap = 105/189/52 (24%/44%/12%)

Query:  60 VRERFGEEVLDACTVNQAYG------GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQR 112
           ++   GE+V+D   V+          G  S  +     + +D  +GI R RG+ I     
Sbjct:  19 LKASIGEDVIDISRVSAEADCFTYDPGFMSTASCQSTITYIDGDKGILRHRGYDI-----  73

Query: 113 LLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHER 172
                K   E+     + +LL+ GE+P+  Q  +  + +   + V  E L  L +     
Sbjct:  74 -----KDLAEKSDFLEVAYLLIYGELPSGEQYNNFTKQVAHHSLVN-ERLHYLFQTFGSS 127

Query: 173 MHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTF 232
            HPM     AV  L        A+          +Y L  A+ +IA++P +AA  Y+ + 
Sbjct: 128 SHPMAIMLAAVGSLS-------AFYPDLLNFKEADYELT-AIRMIAKIPTIAAMSYKYSI 179

Query: 233 HGGKHVPAEKIEKVDD-MGMRLARS-LGFELNEF--DELMRLYLVLHADHEGGNVSAHAV 288
                 P   ++  ++ + M  A     + +N    + L +++ +LHADHE  N S   V
Sbjct: 180 GQPFIYPDNSLDFTENFLHMMFATPCTKYTVNPIIKNALNKIF-ILHADHEQ-NASTSTV 237

Query: 289 RLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWE 348
           R+ GS+ ++P+   + G+  L GP HG AN+ V    + M +++G+     + + +   +
Sbjct: 238 RIAGSSGANPFACISTGIASLWGPAHGGANEAV----INMLKEIGSSEYIPKYIAKA--K 291

Query: 349 TLREGHVIPGFGHAVLRRTDPRYTAQREFA------LKHLPHDEMFQLVSKLYEVVPRVL 402
              +   + GFGH V +  DPR    +E        L  L ++ + Q+  +L  +  +  
Sbjct: 292 DKNDPFRLMGFGHRVYKNYDPRAAVLKETCKEVLKELGQLDNNPLLQIAIELEAIALK-- 349

Query: 403 EEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP--- 459
           +E    +  +PNVD +SGI+ +  G + S  +TVLF ++R +G ++   W      P   
Sbjct: 350 DEYFIERKLYPNVDFYSGIIYKAMG-IPSQMFTVLFAIARTVGWMAQ--WKEMHEDPEQK 406

Query: 460 IERPK 464
           I RP+
Sbjct: 407 ISRPR 411


gb|AAO77177.1| citrate synthase [Bacteroides thetaiotaomicron VPI-5482]
ref|NP_810983.1| citrate synthase [Bacteroides thetaiotaomicron VPI-5482]
(447 aa)

Score: 91 bits (225), Expect: 5.29809e-17
Length: 362, Idn/Pos/Gap = 97/161/40 (26%/44%/11%)

Query: 102 FRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEV 161
           +RG+ + +    + + K  G     E + +LLL+G +P + ++ S  + +    A+  + 
Sbjct:  72 YRGYDVEDISHAIIKEKRFGF----EEVAYLLLSGRLPDKEELASFRELINDNMALEQKT 127

Query: 162 LRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLP 221
              + EL  E  + M   S +V  +      A+         T  +  +  ++ LI++ P
Sbjct: 128 KMNIIEL--EGNNIMNILSRSVLEMYRFDPDAD--------DTSRDNLMRQSIDLISKFP 177

Query: 222 AVAARIY----RNTFHGGKHV--PAEKIEKVDDMGMRLARSLGFELNEFD-ELMRLYLVL 274
            + A  Y      TF    H+  P EK+   ++    L +    +  E D   + L L+L
Sbjct: 178 TIIAYAYNMLRHATFGRSLHIRHPQEKLSIAENFLYMLKK----DYTELDARTLDLLLIL 233

Query: 275 HADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGN 334
            A+H GGN S   VR+  S  +D Y + AAG+  L GPLHG AN +V      ++E + +
Sbjct: 234 QAEHGGGNNSTFTVRVTSSTGTDTYSAIAAGIGSLKGPLHGGANIQVADMFHHLQENIKD 293

Query: 335 ----RPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFA---LKHLPHDEM 387
                 + T   R L  E   +  +I G GHAV   +DPR    +E A    +    +E 
Sbjct: 294 WKSVDEIDTYFTRMLNKEVYNKTGLIYGIGHAVYTISDPRALLLKELARDLAREKGKEEE 353

Query: 388 FQLVSKLYEVVPRVLEEQGKVKNPW----PNVDQHSGILLRYYGLVESNFYTVLFGVSRA 443
           F  +  L E   R +   G+VKN       N+D +SG +    GL +  F T LF ++R 
Sbjct: 354 FAFLELLEE---RAIATFGRVKNNGKTVSSNIDFYSGFVYEMIGLPQEIF-TPLFAMARI 409

Query: 444 LG 445
           +G
Sbjct: 410 VG 411


gb|AAS88993.1| citrate-synthase [Candidatus Rickettsia principis]
(416 aa)

Score: 91 bits (225), Expect: 5.38725e-17
Length: 359, Idn/Pos/Gap = 87/162/51 (24%/45%/14%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LL+ GE+P+  Q  +  + +   + V            HER+H + Q     +      
Sbjct:  87 YLLIYGELPSSEQYNNFTKQVAHHSLV------------HERLHYLFQ-----TFCNSSH 129

Query: 191 KMAEAYAQGAPKSTFWEYCLE--------DALTLIARLPAVAARIYRNTFHGGKHVPAEK 242
            MA   A     S F+   L          A+ +IA++P +A   Y+ +       P   
Sbjct: 130 PMAMMLAAVGSLSAFYPDLLNFKDADYELTAIRMIAKIPTIATMSYKYSIGQPFIYPDNS 189

Query: 243 IEKVDD-MGMRLARS-LGFELNEF--DELMRLYLVLHADHEGGNVSAHAVRLVGSALSDP 298
           ++  ++ + M  A     +++N    + L +++ +LHADHE  N S   VR+ GS+ ++P
Sbjct: 190 LDFTENFLHMMFAMPCTKYKVNPIIKNALNKIF-ILHADHEQ-NASTSTVRIAGSSGANP 247

Query: 299 YLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPG 358
           +   + G+  L GP HG AN+ V    + M +++G+     + + +   +   +   + G
Sbjct: 248 FACISTGIASLWGPAHGGANEAV----INMLKEIGSSEYIPKYIAKA--KDKNDPFRLMG 301

Query: 359 FGHAVLRRTDPRYTAQREFA------LKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPW 412
           FGH V +  DPR    +E        L  L ++ + Q+  +L  +  +  +E    +  +
Sbjct: 302 FGHRVYKNYDPRAAVLKETCKEVLKELGQLDNNPLLQIAIELEAIALK--DEYFIERKLY 359

Query: 413 PNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPKSVTT 468
           PNVD +SGI+    G + +  +TVLF ++R +G ++   W      P   I RP+ + T
Sbjct: 360 PNVDFYSGIIYNAMG-IPTQMFTVLFAIARTVGWMAQ--WKEMHEDPEQKISRPRQLYT 415


gb|AAR17679.1| citrate synthase [Rickettsia amblyommii]
(383 aa)

Score: 91 bits (225), Expect: 5.5238e-17
Length: 407, Idn/Pos/Gap = 98/180/62 (24%/44%/15%)

Query:  80 GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEI 138
           G  S  +     + +D  +GI R RG+ I          K   E+     + +LL+ GE+
Sbjct:  17 GFMSTASCQSTITYIDGDQGILRHRGYDI----------KDLAEKSDFLDVAYLLIYGEL  66

Query: 139 PTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQ 198
           P+  Q  +  + +   + V            +ER+H + Q     +       MA   A 
Sbjct:  67 PSGEQYNNFTKQVAHHSLV------------NERLHYLFQ-----TFCSSSHPMAIMLAA 109

Query: 199 GAPKSTFWEYCLE--------DALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDD-M 249
               S F+   L          A+ +IA++P +AA  Y+ +       P   ++  ++ +
Sbjct: 110 VGSLSAFYPDLLNFKEADYELTAIRMIAKIPTIAAMSYKYSIGQPFIYPDNSLDFTENFL 169

Query: 250 GMRLARS-LGFELNEF--DELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGL 306
            M  A     +++N    + L +++ +LHADHE  N S   VR+ GS+ ++P+   + G+
Sbjct: 170 HMMFATPCTKYKVNPIIKNALNKIF-ILHADHEQ-NASTSTVRIAGSSGANPFACISTGI 227

Query: 307 NGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRR 366
             L GP HG AN+ V    + M +++G+     + + +   +   +   + GFGH V + 
Sbjct: 228 ASLWGPAHGGANEAV----INMLKEIGSSEYIPKYIAKA--KDKNDPFRLMGFGHRVYKN 281

Query: 367 TDPRYTAQREFA------LKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSG 420
            DPR    +E        L  L ++ + Q+  +L  +  +  +E    +  +PNVD +SG
Sbjct: 282 YDPRAAVLKETCKEVLKELGQLDNNPLLQIAIELEAIALK--DEYFIERKLYPNVDFYSG 339

Query: 421 ILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPK 464
           I+ +  G + S  +TVLF ++R +G ++   W      P   I RP+
Sbjct: 340 IIYKAMG-IPSQMFTVLFAIARTVGWMAQ--WKEMYEDPEQKISRPR 383


gb|AAF34354.1| citrate synthase [Rickettsia sp. RpA4]
gb|AAF34353.1| citrate synthase [Rickettsia sp. DnS14]
(411 aa)

Score: 91 bits (225), Expect: 5.61675e-17
Length: 433, Idn/Pos/Gap = 103/190/68 (23%/43%/15%)

Query:  60 VRERFGEEVLDACTVNQAYG------GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQR 112
           ++   GE+V+D   V+          G  S  +     + +D  +GI R RG+ I     
Sbjct:  19 LKASIGEDVIDISRVSAEADCFTYDPGFMSTASCQSTITYIDGDKGILRHRGYDI-----  73

Query: 113 LLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHER 172
                K   E+     + +LL+ GE+P+  Q  +  + +   + V            +ER
Sbjct:  74 -----KDLAEKSDFLEVAYLLIYGELPSGEQYNNFTKQVAHHSLV------------NER 116

Query: 173 MHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLE--------DALTLIARLPAVA 224
           +H + Q     +       MA   A     S F+   L          A+ +IA++P +A
Sbjct: 117 LHYLFQ-----TFCSSSHPMAIMLAAVGSLSAFYPDLLNFKEADYELIAIRMIAKIPTIA 171

Query: 225 ARIYRNTFHGGKHVPAEKIEKVDD-MGMRLARS-LGFELNEF--DELMRLYLVLHADHEG 280
           A  Y+ +       P   ++  ++ + M  A     +++N    + L +++ +LHADHE 
Sbjct: 172 AMSYKYSIGQPFIYPDNSLDFTENFLHMMFATPCTKYKVNPIIKNALNKIF-ILHADHEQ 230

Query: 281 GNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTE 340
            N S   VR+ GS+ ++P+   + G+  L GP HG AN+ V    + M +++G+     +
Sbjct: 231 -NASTSTVRIAGSSGANPFACISTGIASLWGPAHGGANEAV----INMLKEIGSSEYIPK 285

Query: 341 NLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFA------LKHLPHDEMFQLVSKL 394
            + +   +   +   + GFGH V +  DPR    +E        L  L ++ + Q+  +L
Sbjct: 286 YIAKA--KDKNDPFRLMGFGHRVYKNYDPRAAVLKETCKEVLKELGQLDNNPLLQIAIEL 343

Query: 395 YEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDR 454
             +  +  +E    +  +PNVD +SGI+ +  G + S  +TVLF ++R +G ++   W  
Sbjct: 344 EAIALK--DEYFIERKLYPNVDFYSGIIYKAMG-IPSQMFTVLFAIARTIGWMAQ--WKE 398

Query: 455 ALGLP---IERPK 464
               P   I RP+
Sbjct: 399 MHEDPEQKISRPR 411


dbj|BAD05063.1| putative citrate synthase [Tetrahymena thermophila]
(480 aa)

Score: 91 bits (225), Expect: 5.75912e-17
Length: 331, Idn/Pos/Gap = 85/152/27 (25%/45%/8%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LL+ GE+PT++Q E   Q +     +  +VL+++    ++  HPM      ++ L    
Sbjct: 110 YLLIYGELPTKTQFEEFNQRISGHTFLHTDVLQMMKHFRYD-AHPMGMLISTIAALSTFR 168

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDD-- 248
             +     G       +   +    ++ ++P +AA  YR+      + P+  +  VD+  
Sbjct: 169 PGSNPALAGQDIYKDLKIRNKQIYRILGQVPTIAANAYRSRIGRNFNNPSSDLPYVDNFL 228

Query: 249 -MGMRLARSLGFELNEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLN 307
            M  +L  +      +  + + +  +LHA+HE  N S   VR + S+  D Y   A    
Sbjct: 229 YMMDKLNENKYSPHPKLAKALDILFILHAEHEM-NCSTAFVRHLASSGVDVYSCIAGSAA 287

Query: 308 GLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRT 367
            L GP HG AN+ VLR    M E++G+     +N+     +      ++ GFGH V +  
Sbjct: 288 ALYGPKHGGANEAVLR----MLEQIGD----VKNIPSFIDKVKNRKALLFGFGHRVYKNY 339

Query: 368 DPRYTAQREFALKHLPHDEMFQLVSK--LYEVVPRV----LEEQGKVKNP-WPNVDQHSG 420
           DPR    ++ A       E+F++  K  L E+   +    LE++  +K   +PNVD +SG
Sbjct: 340 DPRAKIVKKTAY------EVFEICGKEPLIEIAIELEKIALEDEFFIKRKLYPNVDFYSG 393

Query: 421 ILLRYYGLVESNFYTVLFGVSRALGTLSSLV 451
           ++ R  G   ++ + VLF + R  G L+  V
Sbjct: 394 VIYRAMGF-PTDMFPVLFTIPRVAGWLAHWV 423


gb|AAP92457.1| citrate synthase [Rickettsia heilongjiangensis]
(411 aa)

Score: 91 bits (225), Expect: 5.85603e-17
Length: 433, Idn/Pos/Gap = 103/189/68 (23%/43%/15%)

Query:  60 VRERFGEEVLDACTVNQAYG------GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQR 112
           ++   GE+V+D   V+          G  S  +     + +D  +GI R RG+ I     
Sbjct:  19 LKASIGEDVIDISRVSAEADCFTYDPGFMSTASCQSTITYIDGDKGILRHRGYDI-----  73

Query: 113 LLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHER 172
                K   E+     + +LL+ GE+P+  Q  +  + +   + V            +ER
Sbjct:  74 -----KDLAEKSDFLEVAYLLIYGELPSGEQYNNFTKQVAHHSLV------------NER 116

Query: 173 MHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLE--------DALTLIARLPAVA 224
           +H + Q     +       MA   A     S F+   L          A+ +IA++P +A
Sbjct: 117 LHYLFQ-----TFCSSSHPMAIMLAAVGSLSAFYPDLLNFKEADYELTAIRMIAKIPTIA 171

Query: 225 ARIYRNTFHGGKHVPAEKIEKVDD-MGMRLARSL-GFELNEF--DELMRLYLVLHADHEG 280
           A  Y+ +       P   ++  ++ + M  A     + +N    + L +++ +LHADHE 
Sbjct: 172 AMSYKYSIGQPFIYPDNSLDFTENFLHMMFATPYTKYTVNPIIKNALNKIF-ILHADHEQ 230

Query: 281 GNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTE 340
            N S   VR+ GS+ ++P+   + G+  L GP HG AN+ V    + M +++G+     +
Sbjct: 231 -NASTSTVRIAGSSGANPFACISTGIASLWGPAHGGANEAV----INMLKEIGSSEYIPK 285

Query: 341 NLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFA------LKHLPHDEMFQLVSKL 394
            + +   +   +   + GFGH V +  DPR    +E        L  L ++ + Q+  +L
Sbjct: 286 YIAKA--KDKNDPFRLMGFGHRVYKNYDPRAAVLKETCKEVLKELGQLDNNPLLQIAIEL 343

Query: 395 YEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDR 454
             +  +  +E    +  +PNVD +SGI+ +  G + S  +TVLF ++R +G ++   W  
Sbjct: 344 EAIALK--DEYFIERKLYPNVDFYSGIIYKAMG-IPSQMFTVLFAIARTVGWMAQ--WKE 398

Query: 455 ALGLP---IERPK 464
               P   I RP+
Sbjct: 399 MHEDPEQKISRPR 411


emb|CAC46088.1| CITRATE SYNTHASE PROTEIN [Sinorhizobium meliloti]
ref|NP_385615.1| CITRATE SYNTHASE PROTEIN [Sinorhizobium meliloti 1021]
sp|O33915|CISY_RHIME Citrate synthase
(429 aa)

Score: 91 bits (225), Expect: 5.90509e-17
Length: 406, Idn/Pos/Gap = 104/177/56 (25%/43%/13%)

Query:  80 GMRSLKAMVYETSLLDPQEGIRF-RGFSIPECQRLLPRAKPSGEQPLPEG----LLWLLL 134
           G  S  +   + + +D  EG+   RGF I              EQ    G    + +LLL
Sbjct:  46 GFTSTASCESKITYIDGDEGVLLHRGFPI--------------EQLAEHGDFLEVCYLLL  91

Query: 135 TGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAE 194
            GE+PT++Q       +     V  ++ R       +  HPM      V  L        
Sbjct:  92 YGELPTKAQKADFDYRVTHHTMVHEQMSRFFTGFRRD-AHPMAVMCGCVGALS------- 143

Query: 195 AYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHV--PAEKIEKVDDMGMR 252
           A+   +   T     +  +L +IA++P +AA  Y+  +H G+    P   ++   +  +R
Sbjct: 144 AFYHDSTDITDPHQRMVASLRMIAKMPTIAAMAYK--YHIGQPFVYPKNDLDYASNF-LR 200

Query: 253 LARSLGFELNEFDEL----MRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNG 308
           +  ++  E    + +    M    +LHADHE  N S   VRL GS+ ++P+   AAG+  
Sbjct: 201 MCFAVPCEEYVVNPVLARAMDRIFILHADHEQ-NASTSTVRLAGSSGANPFACIAAGIAC 259

Query: 309 LAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTD 368
           L GP HG AN+      L M  ++G      E + +   +   +   + GFGH V +  D
Sbjct: 260 LWGPAHGGANEAA----LNMLAEIGTVDRIPEYITKA--KDKNDPFRLMGFGHRVYKNYD 313

Query: 369 PRYTAQREFA---LKHLPH--DEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILL 423
           PR    ++     L  L H  D + ++  +L  +   + +E    K  +PN+D +SGI L
Sbjct: 314 PRAKIMQKTTHEVLAELGHKDDPLLEVAMELERIA--LTDEYFIEKKLYPNIDFYSGITL 371

Query: 424 RYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPKSV 466
           +  G   +  +TVLF ++R +G ++   W+  +  P   I RP+ +
Sbjct: 372 KALGF-PTTMFTVLFALARTVGWIAQ--WNEMIEDPEQRIGRPRQL 414


gb|AAF15535.1| citrate synthase [Rickettsia sp. DaE100R]
(411 aa)

Score: 91 bits (225), Expect: 5.95457e-17
Length: 433, Idn/Pos/Gap = 103/189/68 (23%/43%/15%)

Query:  60 VRERFGEEVLDACTVNQAYG------GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQR 112
           ++   GE+V+D   V+          G  S  +     + +D  +GI R RG+ I     
Sbjct:  19 LKASIGEDVIDISRVSAEADCFTYDPGFMSTASCQSTITYIDGDKGILRHRGYDI-----  73

Query: 113 LLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHER 172
                K   E+     + +LL+ GE+P+  Q  +  + +   + V            +ER
Sbjct:  74 -----KDLAEKSDFLEVAYLLIYGELPSGEQYNNFTKQVAHHSLV------------NER 116

Query: 173 MHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLE--------DALTLIARLPAVA 224
           +H + Q     +       MA   A     S F+   L          A+ +IA++P +A
Sbjct: 117 LHYLFQ-----TFCNSSHPMAIMLAAVGSLSAFYPDLLNFKEADYELTAIRMIAKIPTIA 171

Query: 225 ARIYRNTFHGGKHVPAEKIEKVDD-MGMRLARS-LGFELNEF--DELMRLYLVLHADHEG 280
           A  Y+ +       P   ++  ++ + M  A     + +N    + L +++ +LHADHE 
Sbjct: 172 AMSYKYSIGQPFIYPDNSLDFTENFLHMMFATPCTKYTVNPIIKNALNKIF-ILHADHEQ 230

Query: 281 GNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTE 340
            N S   VR+ GS+ ++P+   + G+  L GP HG AN+ V    + M +++G+     +
Sbjct: 231 -NASTSTVRIAGSSGANPFACISTGIASLWGPAHGGANEAV----INMLKEIGSSEYIPK 285

Query: 341 NLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFA------LKHLPHDEMFQLVSKL 394
            + +   +   +   + GFGH V +  DPR    +E        L  L ++ + Q+  +L
Sbjct: 286 YIAKA--KDKNDPFRLMGFGHRVYKNYDPRAVVLKETCKEVLKELGQLDNNPLLQIAIEL 343

Query: 395 YEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDR 454
             +  +  +E    +  +PNVD +SGI+ +  G + S  +TVLF ++R +G ++   W  
Sbjct: 344 EAIALK--DEYFIERKLYPNVDFYSGIIYKAMG-IPSQMFTVLFAIARTVGWMAQ--WKE 398

Query: 455 ALGLP---IERPK 464
               P   I RP+
Sbjct: 399 MHEDPEQKISRPR 411


ref|YP_175301.1| citrate synthase [Bacillus clausii KSM-K16]
dbj|BAD64340.1| citrate synthase [Bacillus clausii KSM-K16]
(373 aa)

Score: 91 bits (225), Expect: 6.00446e-17
Length: 400, Idn/Pos/Gap = 113/178/51 (28%/44%/12%)

Query:  74 VNQAYG-GMRSLKAMVYETSLLDPQEG-IRFRGFSIPECQRLLPRAKPSGEQPLPEGLLW 131
           V Q Y  G+  + A   + S LD ++G I   G+       L+  +K +G       ++ 
Sbjct:   3 VEQTYHPGLDGVIAAETDLSFLDTEQGQIIIHGYD------LIQLSKTNGYL----DIVH  52

Query: 132 LLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESK 191
           LLL GE+P+E +  ++ + L     +P  VL +L  LP    HPM      VS+L     
Sbjct:  53 LLLKGELPSEQERLALAERLSGSYDLPEAVLDVLKRLP-ASTHPMDALRTGVSVLGGFDT 111

Query: 192 MAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGM 251
             +  ++ A +        E A  L+A+LPAV A  YR         P + +    +   
Sbjct: 112 RLDDRSEEANR--------ERAYELLAKLPAVVANSYRILEKKQVLTPKDSLSYSANFLY 163

Query: 252 RLARSLGFELNE--FDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGL 309
            +  ++  EL E  FD+     L+L+++HE  N S  A R++ S LSD Y +    +  L
Sbjct: 164 MITGNVPSELEERVFDQ----SLLLYSEHEMPN-STFAARVIASTLSDMYGALTGAVASL 218

Query: 310 AGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAV-LRRTD 368
            G LHG AN+ V+  LL       N P   E    L    L++   I GFGH V +++ D
Sbjct: 219 KGHLHGGANEAVMYMLLD-----ANSP---EEFETLLSNKLKKKEKIMGFGHRVYMKKID 270

Query: 369 PRYTAQREFALKHLPH----DEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLR 424
           PR    +E AL  L      D + Q+      ++        K K  +PN+D ++  +  
Sbjct: 271 PRALIMKE-ALAELSQAAGDDRLLQMCEAGEALM-------AKEKGLYPNLDYYAAPVYW 322

Query: 425 YYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLPIERPK 464
             G+  S  YT +F  SR  G LS+ V ++     + RP+
Sbjct: 323 MLGIPIS-LYTPIFFSSRTAG-LSAHVIEQHRNNKLFRPR 360


gb|AAB02971.1| citrate synthase [Rickettsia sibirica]
gb|AAB02963.1| citrate synthase [Rickettsia parkeri]
gb|AAB02969.1| citrate synthase [Rickettsia slovaca]
sp|Q59778|CISY_RICSI Citrate synthase
sp|Q59776|CISY_RICSL Citrate synthase
sp|Q59759|CISY_RICPA Citrate synthase
(411 aa)

Score: 91 bits (225), Expect: 6.1055e-17
Length: 433, Idn/Pos/Gap = 103/189/68 (23%/43%/15%)

Query:  60 VRERFGEEVLDACTVNQAYG------GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQR 112
           ++   GE+V+D   V+          G  S  +     + +D  +GI R RG+ I     
Sbjct:  19 LKASIGEDVIDISRVSAEADCFTYDPGFMSTASCQSTITYIDGDKGILRHRGYDI-----  73

Query: 113 LLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHER 172
                K   E+     + +LL+ GE+P+  Q  +  + +   + V            +ER
Sbjct:  74 -----KDLAEKSDFLEVAYLLIYGELPSGEQYNNFTKQVAHHSLV------------NER 116

Query: 173 MHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLE--------DALTLIARLPAVA 224
           +H + Q     +       MA   A     S F+   L          A+ +IA++P +A
Sbjct: 117 LHYLFQ-----TFCSSSHPMAIMLAAVGSLSAFYPDLLNFKEADYELTAIRMIAKIPTIA 171

Query: 225 ARIYRNTFHGGKHVPAEKIEKVDD-MGMRLARS-LGFELNEF--DELMRLYLVLHADHEG 280
           A  Y+ +       P   ++  ++ + M  A     + +N    + L +++ +LHADHE 
Sbjct: 172 AMSYKYSIGQPFIYPDNSLDFTENFLHMMFATPCTKYTVNPIIKNALNKIF-ILHADHEQ 230

Query: 281 GNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTE 340
            N S   VR+ GS+ ++P+   + G+  L GP HG AN+ V    + M +++G+     +
Sbjct: 231 -NASTSTVRIAGSSGANPFACISTGIASLWGPAHGGANEAV----INMLKEIGSSEYIPK 285

Query: 341 NLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFA------LKHLPHDEMFQLVSKL 394
            + +   +   +   + GFGH V +  DPR    +E        L  L ++ + Q+  +L
Sbjct: 286 YIAKA--KDKNDPFRLMGFGHRVYKNYDPRAAVLKETCKEVLKELGQLDNNPLLQIAIEL 343

Query: 395 YEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDR 454
             +  +  +E    +  +PNVD +SGI+ +  G + S  +TVLF ++R +G ++   W  
Sbjct: 344 EAIALK--DEYFIERKLYPNVDFYSGIIYKAMG-IPSQMFTVLFAIARTVGWMAQ--WKE 398

Query: 455 ALGLP---IERPK 464
               P   I RP+
Sbjct: 399 MHEDPEQKISRPR 411


gb|AAB02953.1| citrate synthase [Rickettsia akari]
sp|Q59730|CISY_RICAK Citrate synthase
(411 aa)

Score: 91 bits (225), Expect: 6.20824e-17
Length: 449, Idn/Pos/Gap = 108/199/76 (24%/44%/16%)

Query:  46 VRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYG------GMRSLKAMVYETSLLDPQEG  99
           +R KI     Q+  ++   GE+V+D   V+          G  S  +     + +D  +G
Sbjct:   9 IRGKI----FQLPILKASIGEDVIDISRVSAEVNCFTYDPGFMSTASCKSTITYIDGDKG  64

Query: 100 I-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVP 158
           I R RG++I          K   E+     + +LL+ GE+P+  Q  +  + +   + V 
Sbjct:  65 ILRHRGYNI----------KDLAEKSDFLEVAYLLIYGELPSIEQYNNFTKQVAHHSLV- 113

Query: 159 PEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLE------- 211
                      +ER+H + Q     +       MA   A     S F+   L        
Sbjct: 114 -----------NERLHYLFQ-----TFCSSSHPMAIMLAAIGSLSAFYPDLLNFKEADYE 157

Query: 212 -DALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDD-MGMRLARS-LGFELNEF--DE 266
             A+ +IA++P +AA  Y+ +       P   ++  ++ + M  A     +++N    + 
Sbjct: 158 LTAIRMIAKIPTIAAMSYKYSIGQPFVYPDNSLDFTENFLHMMFATPCTKYKVNPIIKNA 217

Query: 267 LMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLL 326
           L +++ +LHADHE  N S   VR+ GS+ ++ +   + G+  L GP HG AN+ V    +
Sbjct: 218 LNKIF-ILHADHEQ-NASTSTVRIAGSSGANAFACISTGIASLWGPAHGGANEAV----I 271

Query: 327 QMKEKLGNRPMTTENLRELCWETLREGHV--IPGFGHAVLRRTDPRYTAQREFA------ 378
            M +++G    ++EN+ +   +   +     + GFGH V +  DPR +  +E        
Sbjct: 272 NMLKEIG----SSENIPKYIAKAKDKSDPFRLMGFGHRVYKNYDPRASVLKETCKEVLKE 327

Query: 379 LKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLF 438
           L  L ++ + Q+  +L  +  +  +E    +  +PNVD +SGI+ +  G + S  +TVLF
Sbjct: 328 LGQLENNPLLQIAIELEAIALK--DEYFIERKLYPNVDFYSGIIYKAMG-IPSQMFTVLF 384

Query: 439 GVSRALGTLSSLVWDRAL---GLPIERPK 464
            ++R +G ++   W       G  I RP+
Sbjct: 385 AIARTVGWMAQ--WKEMHEDPGQKISRPR 411


dbj|BAD81007.1| putative citrate synthase [uncultured bacterium]
(423 aa)

Score: 90 bits (224), Expect: 7.39716e-17
Length: 412, Idn/Pos/Gap = 109/183/73 (26%/44%/17%)

Query:  83 SLKAMVYETSLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTE 141
           S  A     + +D   G+ R+RG+ I +       AK +  +     + +LLL GE+PT+
Sbjct:  46 STAACASSITYVDGDAGVMRYRGYPIEQLA-----AKSTFLE-----VAYLLLNGELPTK  95

Query: 142 SQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAP 201
            Q+++   D+     V   + + +    H   HPM  F  A++ L         Y     
Sbjct:  96 DQLDAWSFDVTHHTMVHENMRKTICHGFHYDAHPMGMFISAIAAL------GTFYVDAKD 149

Query: 202 KSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFEL 261
            S   +   +  L L+A++P +AA  YR  F  G  +P           +    S+G+  
Sbjct: 150 ISNV-KVLNKQILRLVAKVPTIAAMTYR--FSSG--LPF----------VLPNNSMGYAQ 194

Query: 262 NEFDELMRL----------------YLVLHADHEGGNVSAHAVRLVG-SALSDPYLSFAA 304
           N  + + R+                  +LHADHE  N    A+R+V  +  +DPY + AA
Sbjct: 195 NFLNMMYRIGDDYVVNPVLARALDVLFILHADHEQ-NCGTTAMRIVELTTHTDPYSATAA 253

Query: 305 GLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVL 364
               L GPLHG AN+ V+R L ++ + +   P   E+++        +G +I GFGH V 
Sbjct: 254 AAAALYGPLHGGANEAVVRMLAEIGD-IKKVPAFIESVKR------GDGRLI-GFGHRVY 305

Query: 365 RRTDPRYTAQREFA---LKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGI 421
           +  DPR T  ++ A        ++ +  +  K+ EV   + ++    +  +PNVD +SG+
Sbjct: 306 KNFDPRATIIKKTAYDVFNVTGNNPLLDIALKMEEVA--LNDDYFVSRKLYPNVDFYSGL 363

Query: 422 LLRYYGLVESNFYTVLFGVSRALGTL---SSLVWDRALGLPIERPKSVTTQW 470
           + +  G      +TVLF + R +G L   S L+ D+     I RP+    QW
Sbjct: 364 IYQALGF-PVEMFTVLFAIPRTVGWLAHMSELLKDKE--QKISRPR----QW 408


gb|AAB02974.1| citrate synthase [Rickettsia honei]
gb|AAC83452.1| citrate synthase [Rickettsia honei]
(411 aa)

Score: 90 bits (224), Expect: 7.64821e-17
Length: 433, Idn/Pos/Gap = 103/189/68 (23%/43%/15%)

Query:  60 VRERFGEEVLDACTVNQAYG------GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQR 112
           ++   GE+V+D   V+          G  S  +     + +D  +GI R RG+ I     
Sbjct:  19 LKASVGEDVIDISMVSAEADCFTYDPGFMSTASCQSTITYIDGDKGILRHRGYDI-----  73

Query: 113 LLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHER 172
                K   E+     + +LL+ GE+P+  Q  +  + +   + V            +ER
Sbjct:  74 -----KDLAEKSDFLEVAYLLIYGELPSGEQYNNFTKQVAHHSLV------------NER 116

Query: 173 MHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLE--------DALTLIARLPAVA 224
           +H + Q     +       MA   A     S F+   L          A+ +IA++P +A
Sbjct: 117 LHYLFQ-----TFCSSSHPMAIMLAAVGSLSAFYPDLLNFKEADYELTAIRMIAKIPTIA 171

Query: 225 ARIYRNTFHGGKHVPAEKIEKVDD-MGMRLARS-LGFELNEF--DELMRLYLVLHADHEG 280
           A  Y+ +       P   ++  ++ + M  A     + +N    + L +++ +LHADHE 
Sbjct: 172 AMSYKYSIGQPFIYPDNALDFTENFLHMMFATPCTKYTVNPIIKNALNKIF-ILHADHEQ 230

Query: 281 GNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTE 340
            N S   VR+ GS+ ++P+   + G+  L GP HG AN+ V    + M +++G+     +
Sbjct: 231 -NASTSTVRIAGSSGANPFACISTGIASLWGPAHGGANEAV----INMLKEIGSSEYIPK 285

Query: 341 NLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFA------LKHLPHDEMFQLVSKL 394
            + +   +   +   + GFGH V +  DPR    +E        L  L ++ + Q+  +L
Sbjct: 286 YIAKA--KDKNDPFRLMGFGHRVYKNYDPRAAVLKETCKEVLKELGQLDNNPLLQIAIEL 343

Query: 395 YEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDR 454
             +  +  +E    +  +PNVD +SGI+ +  G + S  +TVLF ++R +G ++   W  
Sbjct: 344 EAIALK--DEYFIERKLYPNVDFYSGIIYKAMG-IPSQMFTVLFAIARTVGWMAQ--WKE 398

Query: 455 ALGLP---IERPK 464
               P   I RP+
Sbjct: 399 MHEDPEQKISRPR 411


gb|AAB02964.1| citrate synthase [Rickettsia rhipicephali]
gb|AAB02967.1| citrate synthase [Rickettsia sp.]
gb|AAB02961.1| citrate synthase [Rickettsia massiliae]
sp|Q59768|CISY_RICRH Citrate synthase
sp|Q59748|CISY_RICMA Citrate synthase
(411 aa)

Score: 90 bits (224), Expect: 8.59589e-17
Length: 433, Idn/Pos/Gap = 102/190/68 (23%/43%/15%)

Query:  60 VRERFGEEVLDACTVNQAYG------GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQR 112
           ++   GE+V+D   V+          G  S  +     + +D  +GI R RG+ I     
Sbjct:  19 LKASIGEDVIDISRVSAEADCFTYDPGFMSTASCQSTITYIDGDKGILRHRGYDI-----  73

Query: 113 LLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHER 172
                K   E+     + +LL+ GE+P+  Q  +  + +   + V            +ER
Sbjct:  74 -----KDLAEKSDFLEVAYLLIYGELPSGEQYNNFTKQVAHHSLV------------NER 116

Query: 173 MHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLE--------DALTLIARLPAVA 224
           +H + Q     +       MA   A     S F+   L          A+ +IA++P +A
Sbjct: 117 LHYLFQ-----TFCSSSHPMAIMLAAVGSLSAFYPDLLNFKEADYELTAIRMIAKIPTIA 171

Query: 225 ARIYRNTFHGGKHVPAEKIEKVDD-MGMRLARS-LGFELNEF--DELMRLYLVLHADHEG 280
           A  Y+ +       P   ++  ++ + M  A     +++N    + L +++ +LHADHE 
Sbjct: 172 AMSYKYSIGQPFIYPDNSLDFTENFLHMMFATPCTKYKVNPIIKNALNKIF-ILHADHEQ 230

Query: 281 GNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTE 340
            N S   VR+ GS+ ++P+   + G+  L GP HG AN+ V    + M +++G+     +
Sbjct: 231 -NASTSTVRIAGSSGANPFACISTGIASLWGPAHGGANEVV----INMLKEIGSSEYIPK 285

Query: 341 NLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFA------LKHLPHDEMFQLVSKL 394
            + +   +   +   + GFGH + +  DPR    +E        L  L ++ + Q+  +L
Sbjct: 286 YIAKA--KDKNDPFRLMGFGHRIYKNYDPRAAVLKETCKEVLKELGQLDNNPLLQIAIEL 343

Query: 395 YEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDR 454
             +  +  +E    +  +PNVD +SGI+ +  G + S  +TVLF ++R +G ++   W  
Sbjct: 344 EAIALK--DEYFIERKLYPNVDFYSGIIYKAMG-IPSQMFTVLFAIARTVGWMAQ--WKE 398

Query: 455 ALGLP---IERPK 464
               P   I RP+
Sbjct: 399 MHEDPEQKISRPR 411


gb|AAR96316.1| citrate synthase [Rickettsia sp. COOPERI]
(383 aa)

Score: 90 bits (224), Expect: 8.81377e-17
Length: 407, Idn/Pos/Gap = 99/179/62 (24%/43%/15%)

Query:  80 GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEI 138
           G  S  +     + +D  +GI R RG+ I          K   E+     + +LL+ GE+
Sbjct:  17 GFMSTASCQSTITYIDGDKGILRHRGYDI----------KDLAEKSDFLEVAYLLIYGEL  66

Query: 139 PTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQ 198
           P+  Q  +  + +   + V            +ER+H + Q     +       MA   A 
Sbjct:  67 PSGEQYNNFTKQVAHHSLV------------NERLHYLFQ-----TFCSSSHPMAIMLAA 109

Query: 199 GAPKSTFWEYCLE--------DALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDD-M 249
               S F+   L          A+ +IA++P +AA  Y+ +       P   ++  ++ +
Sbjct: 110 VGSLSAFYPDLLNFKEADYELTAIRMIAKIPTIAAMSYKYSIGQPFIYPDNSLDFTENFL 169

Query: 250 GMRLARS-LGFELNEF--DELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGL 306
            M  A     + +N    + L +++ +LHADHE  N S   VR+ GS+ ++P+   + G+
Sbjct: 170 HMMFATPCTKYTVNPIIKNALNKIF-ILHADHEQ-NASTSTVRIAGSSGANPFACISTGI 227

Query: 307 NGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRR 366
             L GP HG AN+ V    + M +K+G+     + + +   +   +   + GFGH V + 
Sbjct: 228 ASLWGPAHGGANEAV----INMLKKIGSSEYIPKYIAKA--KDKNDPFRLMGFGHRVYKN 281

Query: 367 TDPRYTAQREFA------LKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSG 420
            DPR    +E        L  L ++ + Q+  +L  +  +  +E    +  +PNVD +SG
Sbjct: 282 YDPRAAVLKEACKEVLKELGQLDNNPLLQIAIELEAIALK--DEYFIERKLYPNVDFYSG 339

Query: 421 ILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPK 464
           I+ +  G + S  +TVLF ++R +G ++   W      P   I RP+
Sbjct: 340 IIYKAMG-IPSQMFTVLFAIARTVGWMAQ--WKEMHEDPEQKISRPR 383


gb|AAB02968.1| citrate synthase [Rickettsia sp.]
(411 aa)

Score: 90 bits (223), Expect: 9.1129e-17
Length: 433, Idn/Pos/Gap = 103/189/68 (23%/43%/15%)

Query:  60 VRERFGEEVLDACTVNQAYG------GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQR 112
           ++   GE+V+D   V+          G  S  +     + +D  +GI R RG+ I     
Sbjct:  19 LKASIGEDVIDISRVSAEADCFTYDPGFMSTASCQSTITYIDGDKGILRHRGYDI-----  73

Query: 113 LLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHER 172
                K   E+     + +LL+ GE+P   Q  +  + +   + V            +ER
Sbjct:  74 -----KDLAEKSDFLEVAYLLIYGELPNGEQYNNFTKQVAHHSLV------------NER 116

Query: 173 MHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLE--------DALTLIARLPAVA 224
           +H + Q     +       MA   A     S F+   L          A+ +IA++P +A
Sbjct: 117 LHYLFQ-----TFCSSSHPMAIMLAAVGSLSAFYPDLLNFKEADYELTAIRMIAKIPTIA 171

Query: 225 ARIYRNTFHGGKHVPAEKIEKVDD-MGMRLARS-LGFELNEF--DELMRLYLVLHADHEG 280
           A  Y+ +       P   ++  ++ + M  A     +++N    + L +++ +LHADHE 
Sbjct: 172 AMSYKYSIGQPFIYPDNSLDFTENFLHMMFATPCTKYKVNPIIKNALNKIF-ILHADHEQ 230

Query: 281 GNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTE 340
            N S   VR+ GS+ ++P+   + G+  L GP HG AN+ V    + M +++G+     +
Sbjct: 231 -NASTSTVRIAGSSGANPFACISTGIASLWGPAHGGANEVV----INMLKEIGSSEYIPK 285

Query: 341 NLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFA------LKHLPHDEMFQLVSKL 394
            + +   +   +   + GFGH V +  DPR    +E        L  L ++ + Q+  +L
Sbjct: 286 YIAKA--KDKNDPFRLMGFGHRVYKNYDPRAAVLKETCKEVLKELGQLDNNPLLQIAIEL 343

Query: 395 YEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDR 454
             +  +  +E    +  +PNVD +SGI+ +  G + S  +TVLF ++R +G ++   W  
Sbjct: 344 EAIALK--DEYFIERKLYPNVDFYSGIIYKAMG-IPSQMFTVLFAIARTVGWMAQ--WKE 398

Query: 455 ALGLP---IERPK 464
               P   I RP+
Sbjct: 399 MHEDPEQKISRPR 411


ref|ZP_00364919.1| COG0372: Citrate synthase [Polaromonas sp. JS666]
(436 aa)

Score: 90 bits (223), Expect: 9.26624e-17
Length: 350, Idn/Pos/Gap = 97/163/32 (27%/46%/9%)

Query: 132 LLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESK 191
           LLL GE+P   Q +     +     V  ++   L     +  HPM   +  V  L     
Sbjct:  93 LLLYGELPNGDQKKDFVSRVTNHTMVNEQMQFFLRGFRRD-AHPMAIMTGLVGALS---- 147

Query: 192 MAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDD-MG 250
              A+   +   T  E+    A+ LIA++P + A  Y+ T       P   +    + + 
Sbjct: 148 ---AFYHDSTDITNPEHREIAAIRLIAKMPTLVAMAYKYTVGQPYMYPKNNLSYAGNFLH 204

Query: 251 MRLARSLG-FELNEFDE--LMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLN 307
           M  A     ++++   E  L R++ +LHADHE  N S   VRL GS+ ++P+ + AAG+ 
Sbjct: 205 MMFATPCEEYKVSPVLERALDRIF-ILHADHEQ-NASTSTVRLCGSSGTNPFAAIAAGVA 262

Query: 308 GLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRT 367
            L GP HG AN+  L  L  + +K G      + ++++  +    G  + GFGH V +  
Sbjct: 263 CLWGPAHGGANEAALNMLGDI-QKNGGVEKIGDFIKQV--KDKNSGVKLMGFGHRVYKNY 319

Query: 368 DPRYTAQREFALK-----HLPHDEMFQLVSKLYEVVPRVLEEQGKV-KNPWPNVDQHSGI 421
           DPR    +E   +      L +D +F+L   L ++    LE+   V +  +PNVD +SGI
Sbjct: 320 DPRAKLMQETCKEVLHEMGLENDPLFKLAMALEKI---ALEDDYFVSRKLYPNVDFYSGI 376

Query: 422 LLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPKSVTT 468
           + R  G +    +T +F ++R +G ++ L  +  +G P   I RP+ + T
Sbjct: 377 VQRAIG-IPVPLFTAIFALARTVGWIAQL--NEMIGDPEYKIGRPRQLFT 423


gb|AAB02973.1| citrate synthase [Rickettsia typhi]
(411 aa)

Score: 90 bits (223), Expect: 9.90587e-17
Length: 349, Idn/Pos/Gap = 91/163/39 (26%/46%/11%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +L++ GE+P+  Q  +    +   A V  E L  L +      HPM     AV  L    
Sbjct:  87 YLMIYGELPSSEQYHNFTTKIAHHALVN-ERLHYLFQTFCSSSHPMAIMLAAVGSLS--- 142

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDD-M 249
               A+          +Y L  A+ +IA++P +AA  Y+ +       P   ++  ++ +
Sbjct: 143 ----AFYPDLLNFNETDYELT-AIRMIAKIPTIAAMSYKYSIGQPFIYPDNSLDFTENFL 197

Query: 250 GMRLARS-LGFELNEF--DELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGL 306
            M  A     +++N    + L +++ +LHADHE  N S   VR+ GS+ ++P+   + G+
Sbjct: 198 HMMFATPCTKYKVNPIIKNALNKIF-ILHADHEQ-NASTSTVRIAGSSGANPFACISTGI 255

Query: 307 NGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHV--IPGFGHAVL 364
             L GP HG AN+ V    + M +++G    ++EN+ +   +   +     + GFGH V 
Sbjct: 256 ASLWGPAHGGANEAV----INMLKEIG----SSENIPKYVAKAKDKNDPFRLMGFGHRVY 307

Query: 365 RRTDPRYTAQREFA------LKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQH 418
           +  DPR    +E        L  L ++ + Q+  +L  +  +  +E    +  +PNVD +
Sbjct: 308 KSYDPRAAVLKETCKEVLNELGQLENNPLLQIAIELEALALK--DEYFIERKLYPNVDFY 365

Query: 419 SGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPK 464
           SGI+ +  G + S  +TVLF ++R +G ++   W      P   I RP+
Sbjct: 366 SGIIYKAMG-IPSQMFTVLFAIARTVGWMAQ--WKEMHEDPEQKISRPR 411


gb|AAB02954.1| citrate synthase [Rickettsia australis]
sp|P51039|CISY_RICAU Citrate synthase
(411 aa)

Score: 90 bits (223), Expect: 1.07679e-16
Length: 435, Idn/Pos/Gap = 105/191/72 (24%/43%/16%)

Query:  60 VRERFGEEVLDACTVNQAYG------GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQR 112
           ++   GE+V+D   V+          G  S  +     + +D  +GI R RG++I     
Sbjct:  19 LKASIGEDVIDISRVSAEADCFTYDPGFMSTASCQSTITYIDGDKGILRHRGYNI-----  73

Query: 113 LLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHER 172
                K   E+     + +LL+ GE+PT  Q  +    +   + V            +ER
Sbjct:  74 -----KDLAEKSDFLEVAYLLIYGELPTIEQYNNFTTQVAHHSLV------------NER 116

Query: 173 MHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLE--------DALTLIARLPAVA 224
           +H + Q     +       MA   A     S F+   L          A+ +IA++P +A
Sbjct: 117 LHYLFQ-----AFCSSSHPMAIMLAAVGSLSAFYPDLLNFKEADYELTAIRMIAKIPTIA 171

Query: 225 ARIYRNTFHGGKHVPAEKIEKVDD-MGMRLARS-LGFELNEF--DELMRLYLVLHADHEG 280
           A  Y+ +       P   ++  ++ + M  A     +++N    + L +++ +LHADHE 
Sbjct: 172 AMSYKYSIGQPFIYPDNSLDFTENFLHMMFATPCTKYKVNPIIKNALNKIF-ILHADHEQ 230

Query: 281 GNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTE 340
            N S   VR+ GS+ ++ +   + G+  L GP HG AN+ V    + M +++G    ++E
Sbjct: 231 -NASTSTVRIAGSSGANAFACISTGIASLWGPAHGGANEAV----INMLKEIG----SSE 281

Query: 341 NLRELCWETLREGHV--IPGFGHAVLRRTDPRYTAQREFA------LKHLPHDEMFQLVS 392
           N+ +   +   +     + GFGH V +  DPR    +E        L  L ++ + Q+  
Sbjct: 282 NIPKFIAKAKDKNDPFRLMGFGHRVYKNYDPRAAVLKETCKAVLKELGQLENNPLLQIAI 341

Query: 393 KLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVW 452
           +L  +  +  +E    +  +PNVD +SGI+ +  G + S  +TVLF ++R +G ++   W
Sbjct: 342 ELEAIALK--DEYFIERKLYPNVDFYSGIIYKAMG-IPSQMFTVLFAIARTVGWMAQ--W 396

Query: 453 DRALGLP---IERPK 464
                 P   I RP+
Sbjct: 397 KEMHEDPEQKISRPR 411


gb|AAB02958.1| citrate synthase [Rickettsia conorii]
(411 aa)

Score: 90 bits (223), Expect: 1.16076e-16
Length: 433, Idn/Pos/Gap = 103/188/68 (23%/43%/15%)

Query:  60 VRERFGEEVLDACTVNQAYG------GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQR 112
           ++   GE+V+D   V+          G  S  +     + +D  +GI R RG+ I     
Sbjct:  19 LKASIGEDVIDISRVSAEADCFTYDPGFMSTASCQSTITYIDGDKGILRHRGYDI-----  73

Query: 113 LLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHER 172
                K   E+     + +LL+ GE+P+  Q  +  + +   + V            +ER
Sbjct:  74 -----KDLAEKSDFLEVAYLLIYGELPSGEQYNNFTKQVAHHSLV------------NER 116

Query: 173 MHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLE--------DALTLIARLPAVA 224
           +H + Q     +       MA   A     S F+   L          A+ +IA++P +A
Sbjct: 117 LHYLFQ-----TFCSSSHPMAIMLAAVGSLSAFYPDLLNFKEADYELTAIRMIAKIPTIA 171

Query: 225 ARIYRNTFHGGKHVPAEKIEKVDD-MGMRLARS-LGFELNEF--DELMRLYLVLHADHEG 280
           A  Y+ +       P   ++  ++ + M  A     + +N    + L +++ +LHADHE 
Sbjct: 172 AMSYKYSIGQPFIYPDNSLDFTENFLHMMFATPCTKYTVNPIIKNALNKIF-ILHADHEQ 230

Query: 281 GNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTE 340
            N S   VR+ GS+ ++P+   + G+  L GP HG AN+ V    + M +++G+     +
Sbjct: 231 -NASTSTVRIAGSSGANPFACISTGIASLWGPAHGGANEAV----INMIKEIGSSEYIPK 285

Query: 341 NLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFA------LKHLPHDEMFQLVSKL 394
            + +   +   +   + GFGH V +  DPR    +E        L  L ++   Q+  +L
Sbjct: 286 YIAKA--KDKNDPFRLMGFGHRVYKNYDPRAAVLKETCKEVLKELGQLDNNPFLQIAIEL 343

Query: 395 YEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDR 454
             +  +  +E    +  +PNVD +SGI+ +  G + S  +TVLF ++R +G ++   W  
Sbjct: 344 EAIALK--DEYFIERKLYPNVDFYSGIIYKAMG-IPSQMFTVLFAIARTVGWMAQ--WKE 398

Query: 455 ALGLP---IERPK 464
               P   I RP+
Sbjct: 399 MHEDPEQKISRPR 411


gb|AAM49621.1| citrate synthase [Rickettsia sp. FLA1]
gb|AAB02960.1| citrate synthase [Rickettsia japonica]
sp|Q59742|CISY_RICJA Citrate synthase
(411 aa)

Score: 90 bits (222), Expect: 1.29375e-16
Length: 433, Idn/Pos/Gap = 102/189/68 (23%/43%/15%)

Query:  60 VRERFGEEVLDACTVNQAYG------GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQR 112
           ++   GE+V+D   V+          G  S  +     + +D  +GI R RG+ I     
Sbjct:  19 LKASIGEDVIDISRVSAEADCFTYDPGFMSTASCQSTVTYIDGDKGILRHRGYDI-----  73

Query: 113 LLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHER 172
                K   E+     + +LL+ GE+P+  Q  +  + +   + V            ++R
Sbjct:  74 -----KDLAEKSDFLEVAYLLIYGELPSGEQYNNFTKQVAHHSLV------------NDR 116

Query: 173 MHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLE--------DALTLIARLPAVA 224
           +H + Q     +       MA   A     S F+   L          A+ +IA++P +A
Sbjct: 117 LHYLFQ-----TFCSSSHPMAIMLAAVGSLSAFYPDLLNFKEADYELTAIRMIAKIPTIA 171

Query: 225 ARIYRNTFHGGKHVPAEKIEKVDD-MGMRLARSL-GFELNEF--DELMRLYLVLHADHEG 280
           A  Y+ +       P   ++  ++ + M  A     + +N    + L +++ +LHADHE 
Sbjct: 172 AMSYKYSIGQPFIYPDNSLDFTENFLHMMFATPYTKYTVNPIIKNALNKIF-ILHADHEQ 230

Query: 281 GNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTE 340
            N S   VR+ GS+ ++P+   + G+  L GP HG AN+ V    + M +++G+     +
Sbjct: 231 -NASTSTVRIAGSSGANPFACISTGIASLWGPAHGGANEAV----INMLKEIGSSEYIPK 285

Query: 341 NLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFA------LKHLPHDEMFQLVSKL 394
            + +   +   +   + GFGH V +  DPR    +E        L  L ++ + Q+  +L
Sbjct: 286 YIAKA--KDKNDPFRLMGFGHRVYKNYDPRAAVLKETCKEVLKELGQLDNNPLLQIAIEL 343

Query: 395 YEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDR 454
             +  +  +E    +  +PNVD +SGI+ +  G + S  +TVLF ++R +G ++   W  
Sbjct: 344 EAIALK--DEYFIERKLYPNVDFYSGIIYKAMG-IPSQMFTVLFAIARTVGWMAQ--WKE 398

Query: 455 ALGLP---IERPK 464
               P   I RP+
Sbjct: 399 MHEDPEQKISRPR 411


gb|AAB18272.1| citrate synthase [Rickettsia montanensis]
(411 aa)

Score: 90 bits (222), Expect: 1.38305e-16
Length: 443, Idn/Pos/Gap = 104/194/71 (23%/43%/16%)

Query:  53 MRAQVHEV---RERFGEEVLDACTVNQAYG------GMRSLKAMVYETSLLDPQEGI-RF 102
           +R ++ E+   +   GE+V+D   V+          G  S  +     + +D  +GI R 
Sbjct:   9 IRGKIFELPILKASIGEDVIDISRVSAEADCFTYDPGFMSTASCQSTITYIDGDKGILRH  68

Query: 103 RGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVL 162
           RG+ I          K   E+     + +LL+ GE+P+  Q  +  + +   + V     
Sbjct:  69 RGYDI----------KDLAEKSDFLEVAYLLIYGELPSGEQYNNFTKQVAHHSLV----- 113

Query: 163 RLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLE--------DAL 214
                  +ER+H + Q     +       MA   A     S F+   L          A+
Sbjct: 114 -------NERLHYLFQ-----TFCSSSHPMAIMLAAVGSLSAFYPDLLNFKEADYELTAI 161

Query: 215 TLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDD-MGMRLARS-LGFELNEF--DELMRL 270
            +IA++P +AA  Y+ +       P   ++  ++ + M  A     +++N    + L ++
Sbjct: 162 RMIAKIPTIAAMSYKYSIGQPFIYPDNSLDFTENFLHMMFATPCTKYKVNPIIKNALNKI 221

Query: 271 YLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKE 330
           + +LHADHE  N S   VR+  S+ ++P+   + G+  L GP HG AN+ V    + M +
Sbjct: 222 F-ILHADHEQ-NASTSTVRIASSSGANPFACISTGIASLWGPAHGGANEAV----INMLK 275

Query: 331 KLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFA------LKHLPH 384
           ++G+     + + +   +   +   + GFGH V +  DPR    +E        L  L +
Sbjct: 276 EIGSSEYIPKYIAKA--KDKNDPFRLMGFGHRVYKNYDPRAAVLKETCKEVLKELGQLDN 333

Query: 385 DEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRAL 444
           + + Q+  +L  +  +  +E    +  +PNVD +SGI+ +  G + S  +TVLF ++R +
Sbjct: 334 NPLLQIAIELEAIALK--DEYFIERKLYPNVDFYSGIIYKAMG-IPSQMFTVLFAIARTV 390

Query: 445 GTLSSLVWDRALGLP---IERPK 464
           G ++   W      P   I RP+
Sbjct: 391 GWMAQ--WKEMHEDPEQKISRPR 411


gb|AAD01934.1| citrate synthase [Rickettsia sp.]
(373 aa)

Score: 90 bits (222), Expect: 1.44197e-16
Length: 388, Idn/Pos/Gap = 93/174/57 (23%/44%/14%)

Query:  80 GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEI 138
           G  S  +     + +D  +GI R RG+ I          K   E+     + +LL+ GE+
Sbjct:  14 GFMSTASCQSTITYIDGDQGILRHRGYDI----------KDLAEKSDFLDVAYLLIYGEL  63

Query: 139 PTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQ 198
           P+  Q  +  + +   + V            +ER+H + Q     +       MA   A 
Sbjct:  64 PSGEQYNNFTKQVAHHSLV------------NERLHYLFQ-----TFCSSSHPMAIMLAA 106

Query: 199 GAPKSTFWEYCLE--------DALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDD-M 249
               S F+   L          A+ +IA++P +AA  Y+ +       P   ++  ++ +
Sbjct: 107 VGSLSAFYPDLLNFKEADYELTAIRMIAKIPTIAAMSYKYSIGQPFIYPDNSLDFTENFL 166

Query: 250 GMRLARS-LGFELNEF--DELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGL 306
            M  A     +++N    + L +++ +LHADHE  N S   VR+ GS+ ++P+   + G+
Sbjct: 167 HMMFATPCTKYKVNPIIKNALNKIF-ILHADHEQ-NASTSTVRIAGSSGANPFACISTGI 224

Query: 307 NGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRR 366
             L GP HG AN+ V    + M +++G+     + + +   +   +   + GFGH V + 
Sbjct: 225 ASLWGPAHGGANEAV----INMLKEIGSSEYIPKYIAKA--KDKNDPFRLMGFGHRVYKN 278

Query: 367 TDPRYTAQREFA------LKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSG 420
            DPR    +E        L  L ++ + Q+  +L  +  +  +E    +  +PNVD +SG
Sbjct: 279 YDPRAAVLKETCKEVLKELGQLDNNPLLQIAIELEAIALK--DEYFIERKLYPNVDFYSG 336

Query: 421 ILLRYYGLVESNFYTVLFGVSRALGTLS 448
           I+ +  G + S  +TVLF ++R +G ++
Sbjct: 337 IIYKAMG-IPSQMFTVLFAIARTVGWMA 363


emb|CAG43425.1| citrate synthase II [Staphylococcus aureus subsp. aureus MSSA476]
ref|YP_186579.1| citrate synthase [Staphylococcus aureus subsp. aureus COL]
dbj|BAB57857.1| citrate synthase II [Staphylococcus aureus subsp. aureus Mu50]
dbj|BAB95504.1| citrate synthase II [Staphylococcus aureus subsp. aureus MW2]
ref|NP_374806.1| citrate synthase II [Staphylococcus aureus subsp. aureus N315]
dbj|BAB42785.1| citrate synthase II [Staphylococcus aureus subsp. aureus N315]
ref|YP_043742.1| citrate synthase II [Staphylococcus aureus subsp. aureus MSSA476]
ref|NP_646456.1| citrate synthase II [Staphylococcus aureus subsp. aureus MW2]
pir||D89953 citrate synthase II [imported] - Staphylococcus aureus  (strain N315)
gb|AAW36846.1| citrate synthase [Staphylococcus aureus subsp. aureus COL]
ref|NP_372219.1| citrate synthase II [Staphylococcus aureus subsp. aureus Mu50]
(373 aa)

Score: 90 bits (222), Expect: 1.47852e-16
Length: 331, Idn/Pos/Gap = 87/149/36 (26%/45%/10%)

Query: 127 EGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLL 186
           E +++LL    +P E ++  +   L +   + P V    +E   + +HPMT    ++S +
Sbjct:  43 EEVIFLLWNYRLPNEEELAHLKGKLNQYMTLNPRVYTHFEEYVTDHVHPMTALRTSLSYI 102

Query: 187 QHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKV 246
            H    AE  +         E   E A+ + A++ ++     R         P   +   
Sbjct: 103 AHFDPDAENESD--------ENRYERAMRIQAKVASLVTAFARVRQDKEPLKPNPDLSYA 154

Query: 247 DDMGMRLARSL--GFELNEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAA 304
            +    L   L    E+  F++     L+LHADHE  N SA   R   S+LSD Y    A
Sbjct: 155 ANFLYMLRGELPTDIEVEAFNKA----LILHADHEL-NASAFTARCAVSSLSDMYSGIVA 209

Query: 305 GLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVL 364
            +  L GPLHG AN++V+  L ++         + EN+     E       + GFGH V 
Sbjct: 210 AVGSLKGPLHGGANEQVMTMLSEIG--------SIENVDAYLDEKFANKDKVMGFGHRVY 261

Query: 365 RRTDPRYTAQREFA---LKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGI 421
           +  DPR    RE +    K    +E+F++  K+ +   R+ EE+G +    PNVD +S  
Sbjct: 262 KDGDPRAKYLREMSRQITKDAGREELFEMSVKMEK---RMAEEKGLI----PNVDFYSAS 314

Query: 422 LLRYYGL-VESNFYTVLFGVSRALGTLSSLV 451
           +  Y+ + +  + +T +F VSR+ G ++ ++
Sbjct: 315 V--YHCMEIPHDLFTPIFAVSRSAGWIAHIL 343


ref|ZP_00187318.2| COG0372: Citrate synthase [Rubrobacter xylanophilus DSM 9941]
(371 aa)

Score: 89 bits (221), Expect: 1.54151e-16
Length: 385, Idn/Pos/Gap = 107/169/52 (27%/43%/13%)

Query:  98 EGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAV 157
           + + +RG+ I E            E+   E ++ LL+ GE+P   Q+E     L     +
Sbjct:  26 DSLEYRGYPIEEL----------AERATFEEVMHLLIRGELPDRRQLEEYTGRLSGMRKI  75

Query: 158 PPEVLRLLDELPHERMHPMTQFSVAVSLL---QHESKMAEAYAQGAPKSTFWEYCLEDAL 214
           P E+  +L+ +P    HPM       S+L   +HE +  +A   G               
Sbjct:  76 PQELRDVLERIP-ASTHPMEVLRTGCSMLGTLEHEGEGRDAREIGE-------------- 120

Query: 215 TLIARLPAVAARIYRNTFHG-GKHVPAEKIEKVDDMGMRLARSL-GFELNEFDE-LMRLY 271
            LI+ LP+V   +Y + F G GK +  +  E    +     R L G E  E +   + + 
Sbjct: 121 RLISCLPSVL--LYWHHFAGSGKRIETDTGEH--SLAGHFLRLLHGREPGEEERRAVDVS 176

Query: 272 LVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEK 331
           L+L+A+HE  N S    R++ S  SD Y +    +  L GPLHG AN+  + ++    E+
Sbjct: 177 LILYAEHEF-NASTFTARIIASTGSDFYSAITGAIGALRGPLHGGANEAAMAFI----ER 231

Query: 332 LGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALK-HLPHDEMFQL 390
             +       LR    E L  G  + GFGH V  R DPR    + ++ +    H+E +  
Sbjct: 232 FRSAEEAERGLR----EALSRGERLMGFGHPVYTRVDPRSDIIKGWSRRLSEGHEEGY-- 285

Query: 391 VSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSL 450
              LYEV  R+     + KN +PN+D +S    R+ G + +  +T LF  SR  G  + +
Sbjct: 286 ---LYEVSERIERILHEEKNLFPNLDFYSASAYRFCG-IPTEMFTPLFVFSRTSGWTAHV 341

Query: 451 VWDRALGLPIERPKSVTTQWIREHF 475
           +  R  G  I RP +  T   R  F
Sbjct: 342 IEQRESG-KIIRPSANYTGPERRPF 365


gb|AAB02972.1| citrate synthase [Rickettsia sp.]
(411 aa)

Score: 89 bits (221), Expect: 1.60718e-16
Length: 433, Idn/Pos/Gap = 103/189/68 (23%/43%/15%)

Query:  60 VRERFGEEVLDACTVNQAYG------GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQR 112
           ++   GE+V+D   V+          G  S  +     + +D  +GI R RG+ I     
Sbjct:  19 LKASIGEDVIDISRVSAEADCFTYDPGFMSTASCQSTITYIDGDKGILRHRGYDI-----  73

Query: 113 LLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHER 172
                K   E+     + +LL+ GE+P+  Q  +  + +   + V            +ER
Sbjct:  74 -----KDLAEKSDFLEVAYLLIYGELPSGEQYNNFTKQVAHHSLV------------NER 116

Query: 173 MHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLE--------DALTLIARLPAVA 224
           +H + Q     +       MA   A     S F+   L          A+ +IA++P +A
Sbjct: 117 LHYLFQ-----TFCSSSHPMAIMLAAVGSLSAFYPDLLNFKEADYELTAIRMIAKIPTIA 171

Query: 225 ARIYRNTFHGGKHVPAEKIEKVDD-MGMRLARS-LGFELNEF--DELMRLYLVLHADHEG 280
           A  Y+ +       P   ++  ++ + M  A     + +N    + L +++ +LHADHE 
Sbjct: 172 AMSYKYSIGQPFIYPDNSLDFTENFLHMMFATPCTKYTVNPIIKNALNKIF-ILHADHEQ 230

Query: 281 GNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTE 340
            N S   VR+ GS+ ++P+   + G+  L GP HG AN+ V    + M +++G+     +
Sbjct: 231 -NASTSTVRIAGSSGANPFACISTGIASLWGPAHGGANEAV----INMLKEIGSSEYIPK 285

Query: 341 NLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFA------LKHLPHDEMFQLVSKL 394
            + +   +   +   + GFGH V +  DPR    +E        L  L ++ + Q+  +L
Sbjct: 286 YIAKA--KDKNDPFRLMGFGHRVYKNYDPRAAVLKETCKEVLKELGQLDNNPLLQIAIEL 343

Query: 395 YEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDR 454
             +  +  +E    +  +PNVD +SGI+ +  G + S  +TVLF ++R +G ++   W  
Sbjct: 344 EAIALK--DEYFIERKLYPNVDFYSGIIYKAMG-IPSQMFTVLFVIARTVGWMAQ--WKE 398

Query: 455 ALGLP---IERPK 464
               P   I RP+
Sbjct: 399 MHEDPEQKISRPR 411


ref|ZP_00332423.1| COG0372: Citrate synthase [Streptococcus suis 89/1591]
(372 aa)

Score: 89 bits (221), Expect: 1.60718e-16
Length: 350, Idn/Pos/Gap = 98/158/47 (28%/45%/13%)

Query: 127 EGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLL 186
           E +++LL    +PT+ ++    + L++  A+   V + +       +HPM+     VSLL
Sbjct:  43 EEVIYLLWNLHLPTQIELNYFEKSLRKEYAISDAVEQCILIQSRRHLHPMSVLRSTVSLL 102

Query: 187 QHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLP---AVAARIYRNTFHGGKHVPAEKI 243
              +  AE  +         E   E ++ ++ ++P   A  AR+ R        VP   I
Sbjct: 103 GVYNVHAEENS--------LEALYEQSIQIMGKVPTIIATFARLRRGL------VP---I 145

Query: 244 EKVDDMGMRLARSLGFELN---EFDELMRLY---LVLHADHEGGNVSAHAVRLVGSALSD 297
           E   D+G   A +  + LN     D  ++ +   LVLHADHE  N S  A R+  S L+D
Sbjct: 146 EPRSDLG--FAANFLYMLNGEEPSDLQIKAFNKALVLHADHEL-NASTFAARVTASTLTD 202

Query: 298 PYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIP 357
            Y      +  L G LHG AN+ V   LL ++E        + +      + L     I 
Sbjct: 203 LYSCVTTAIGTLKGSLHGGANERVFDMLLAIRE--------SGDAERYLQKKLDSKEKIM 254

Query: 358 GFGHAVLRRTDPRYTAQREFA--LKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNV 415
           GFGH V +  DPR    +E A  L     DE F  +S+  EV   +  ++G +    PNV
Sbjct: 255 GFGHRVYKTVDPRQEYLKEMARDLTFGTDDEAFYRLSE--EVESFIKNKKGLI----PNV 308

Query: 416 DQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLPIERPKS 465
           D +S  +    G ++S+ +T++F +SR  G ++ +   R     I RP+S
Sbjct: 309 DFYSATVYHVLG-IDSDIFTLIFAMSRMAGWIAHVQEQRKNNKLI-RPRS 356


ref|YP_041161.1| citrate synthase II [Staphylococcus aureus subsp. aureus MRSA252]
emb|CAG40765.1| citrate synthase II [Staphylococcus aureus subsp. aureus MRSA252]
(373 aa)

Score: 89 bits (221), Expect: 1.63422e-16
Length: 331, Idn/Pos/Gap = 87/149/36 (26%/45%/10%)

Query: 127 EGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLL 186
           E +++LL    +P E ++  +   L +   + P V    +E   + +HPMT    ++S +
Sbjct:  43 EEVIFLLWNYRLPNEEELAHLKGKLNQYMTLNPRVYTHFEEYVTDHVHPMTALRTSLSYI 102

Query: 187 QHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKV 246
            H    AE  +         E   E A+ + A++ ++     R         P   +   
Sbjct: 103 AHFDPDAENESD--------ENRYERAMRIQAKVASLVTAFARVRQDKEPIKPNPDLSYA 154

Query: 247 DDMGMRLARSL--GFELNEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAA 304
            +    L   L    E+  F++     L+LHADHE  N SA   R   S+LSD Y    A
Sbjct: 155 ANFLYMLRGELPTDIEVEAFNKA----LILHADHEL-NASAFTARCAVSSLSDMYSGIVA 209

Query: 305 GLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVL 364
            +  L GPLHG AN++V+  L ++         + EN+     E       + GFGH V 
Sbjct: 210 AVGSLKGPLHGGANEQVMTMLSEIG--------SIENVDAYLDEKFANKDKVMGFGHRVY 261

Query: 365 RRTDPRYTAQREFA---LKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGI 421
           +  DPR    RE +    K    +E+F++  K+ +   R+ EE+G +    PNVD +S  
Sbjct: 262 KDGDPRAKYLREMSRQITKDAGREELFEMSVKMEK---RMAEEKGLI----PNVDFYSAS 314

Query: 422 LLRYYGL-VESNFYTVLFGVSRALGTLSSLV 451
           +  Y+ + +  + +T +F VSR+ G ++ ++
Sbjct: 315 V--YHCMEIPHDLFTPIFAVSRSAGWIAHIL 343


gb|AAL01665.1| citrate synthase [Ehrlichia risticii]
(398 aa)

Score: 89 bits (221), Expect: 1.64792e-16
Length: 349, Idn/Pos/Gap = 96/153/47 (27%/43%/13%)

Query: 113 LLPRAKPSGEQPLPEGLL---WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELP 169
           LL R  P  E       L   +LL+ G++P         + +K    +P  VL+ +   P
Sbjct:  58 LLHRGYPIEELAQTSDFLQVGYLLINGKLPDSIATREFEEKIKHVPQLPECVLKNIRSFP 117

Query: 170 HERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYR 229
               HPM   +V +S L   + +A  Y +            E  L L+A  P + A IYR
Sbjct: 118 -TSAHPM---AVLISAL---ASLASVYGEMDFH--------EKKLLLVAYTPWLVAYIYR 162

Query: 230 NTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDE-------LMRLYLVLHADHEGGN 282
                  H+ +++  + D   +RL  +  F    F E       ++    +LHADH G  
Sbjct: 163 -------HINSQEFIEPD---IRLPYTENFLYMMFGEKKPKDAEILDKIFILHADH-GQT 211

Query: 283 VSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENL 342
            S    R+V S+ + P ++ +A    L GPLHG AN+ VL  L  + E       + EN+
Sbjct: 212 ASTSVARMVVSSGASPIVACSAATASLWGPLHGGANERVLEMLRGIIE-------SGENV 264

Query: 343 RELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDE-MFQLVSKLYEVVPRV 401
                   R+   + GFGH V +  DPR    ++ A   L  D  + +   KL  +  R 
Sbjct: 265 ENFIERVKRKEERLMGFGHRVYKNYDPRAAILKQKAHDVLKADSPILKTAGKLETIATR- 323

Query: 402 LEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSL 450
            EE    +  +PNVD +SGI+L   G + S  +T +F ++R +G ++ +
Sbjct: 324 -EEYFLSRKLYPNVDFYSGIVLDALG-IPSCMFTPIFALARTVGWVAQI 370


gb|AAB97876.1| citrate synthase [Rhizobium tropici]
sp|P51037|CISY_RHITR Citrate synthase, chromosomal
(429 aa)

Score: 89 bits (221), Expect: 1.76167e-16
Length: 352, Idn/Pos/Gap = 93/156/37 (26%/44%/10%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LLL GE+PT +Q +     +     V  ++ R       +  HPM      V  L    
Sbjct:  88 YLLLYGELPTAAQKKDFDYRVVHHTMVHEQMSRFFTGFRRD-AHPMAVMCGCVGALS--- 143

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHV--PAEKIEKVDD 248
               A+   +   T     +  +L +IA++P +AA  Y+  +H G+    P   ++   +
Sbjct: 144 ----AFYHDSTDITDPHQRMVASLRMIAKMPTLAAMAYK--YHIGQPFVYPKNDLDYASN 197

Query: 249 MGMRLARSLGFELNEFDEL----MRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAA 304
             +R+  ++  E    + +    M    +LHADHE  N S   VRL GS+ ++P+   AA
Sbjct: 198 F-LRMCFAVPCEEYVVNPVLARAMDRIFILHADHEQ-NASTSTVRLAGSSGANPFACIAA 255

Query: 305 GLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVL 364
           G+  L GP HG AN+      L M  ++G      E +     +   +   + GFGH V 
Sbjct: 256 GIACLWGPAHGGANEAA----LNMLTEIGTVDRIPEYIARA--KDKNDPFRLMGFGHRVY 309

Query: 365 RRTDPRY-----TAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHS 419
           +  DPR      TA        +  D +  +  +L  +   + ++    K  +PNVD +S
Sbjct: 310 KNYDPRAKIMQKTAHEVLGELGIKDDPLLDIAIELERIA--LTDDYFIEKKLYPNVDFYS 367

Query: 420 GILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPKSVTT 468
           GI L+  G   +  +TVLF ++R +G ++   W+  +  P   I RP+ V T
Sbjct: 368 GITLKALGF-PTTMFTVLFALARTVGWIAQ--WNEMIEDPDQRIGRPRHVYT 416


ref|ZP_00196285.2| COG0372: Citrate synthase [Mesorhizobium sp. BNC1]
(429 aa)

Score: 89 bits (221), Expect: 1.80632e-16
Length: 367, Idn/Pos/Gap = 96/156/67 (26%/42%/18%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LLL GE+PT++Q E     + R   +  ++ R       +  HPM      V  L    
Sbjct:  88 YLLLYGELPTKAQKEDFDLRVTRHTMIHEQMSRFFTGFRRD-AHPMAVMCGVVGALS--- 143

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYR------------------NTF 232
               A+   +   +     +  ++ +IA++P +AA  Y+                  N  
Sbjct: 144 ----AFYHDSTDISDPHQRMVASIRMIAKMPTIAAMAYKYHIGQPFMYPRNELSYAANFL 199

Query: 233 HGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVLHADHEGGNVSAHAVRLVG 292
           H    VP E+  KV+ +   LAR+           M    +LHADHE  N S   VRL G
Sbjct: 200 HMCFAVPCEEY-KVNPV---LARA-----------MDRIFILHADHEQ-NASTSTVRLAG 243

Query: 293 SALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLRE 352
           S+ ++P+   AAG+  L GP HG AN+      L M  ++G+     E +     +   +
Sbjct: 244 SSGANPFACIAAGIACLWGPAHGGANEAA----LNMLAEIGSVDRIPEYIARA--KDKND 297

Query: 353 GHVIPGFGHAVLRRTDPR--------YTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEE 404
              + GFGH V +  DPR        +    E  +K  P  ++   + ++       +E 
Sbjct: 298 PFRLMGFGHRVYKNYDPRAKIMQKTCHEVLSELGIKDDPQLDIAMELERIALTDEYFIE- 356

Query: 405 QGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IE 461
               K  +PN+D +SGI L+  G   +  +TVLF V+R +G ++   W   +  P   I 
Sbjct: 357 ----KKLYPNIDFYSGITLKALGF-PTTMFTVLFAVARTVGWIAQ--WKEMIEDPQQKIG 409

Query: 462 RPKSVTT 468
           RP+ + T
Sbjct: 410 RPRQLYT 416


gb|AAF34352.1| citrate synthase [Rickettsia sp. DnS28]
(411 aa)

Score: 89 bits (221), Expect: 1.80632e-16
Length: 433, Idn/Pos/Gap = 102/190/68 (23%/43%/15%)

Query:  60 VRERFGEEVLDACTVNQAYG------GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQR 112
           ++   GE+V+D   V+          G  S  +     + +D  +GI R RG+ I     
Sbjct:  19 LKASIGEDVIDISRVSAEADCFTYDPGFMSTASCQSTITYIDGDKGILRHRGYDI-----  73

Query: 113 LLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHER 172
                K   E+     + +LL+ G++P+  Q  +  + +   + V            +ER
Sbjct:  74 -----KDLAEKSDFLEVAYLLIYGKLPSGEQYNNFTKQVAHHSLV------------NER 116

Query: 173 MHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLE--------DALTLIARLPAVA 224
           +H + Q     +       MA   A     S F+   L          A+ +IA++P +A
Sbjct: 117 LHYLFQ-----TFCSSSHPMAIMLAAVGSLSAFYPDLLNFKEADYELIAIRMIAKIPTIA 171

Query: 225 ARIYRNTFHGGKHVPAEKIEKVDD-MGMRLARS-LGFELNEF--DELMRLYLVLHADHEG 280
           A  Y+ +       P   ++  ++ + M  A     +++N    + L +++ +LHADHE 
Sbjct: 172 AMSYKYSIGQPFIYPDNSLDFTENFLHMMFATPCTKYKVNPIIKNALNKIF-ILHADHEQ 230

Query: 281 GNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTE 340
            N S   VR+ GS+ ++P+   + G+  L GP HG AN+ V    + M +++G+     +
Sbjct: 231 -NASTSTVRIAGSSGANPFACISTGIASLWGPAHGGANEAV----INMLKEIGSSKYIPK 285

Query: 341 NLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFA------LKHLPHDEMFQLVSKL 394
            + +   +   +   + GFGH V +  DPR    +E        L  L ++ + Q+  +L
Sbjct: 286 YIAKA--KDKNDPFRLMGFGHRVYKNYDPRAAVLKETCKEVLKELGQLDNNPLLQIAIEL 343

Query: 395 YEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDR 454
             +  +  +E    +  +PNVD +SGI+ +  G + S  +TVLF ++R +G ++   W  
Sbjct: 344 EAIALK--DEYFIERKLYPNVDFYSGIIYKAMG-IPSQMFTVLFAIARTIGWMAQ--WKE 398

Query: 455 ALGLP---IERPK 464
               P   I RP+
Sbjct: 399 MHEDPEQKISRPR 411


emb|CAB88291.1| citrate synthase-like protein [Arabidopsis thaliana]
gb|AAM20462.1| citrate synthase-like protein [Arabidopsis thaliana]
gb|AAN72180.1| citrate synthase-like protein [Arabidopsis thaliana]
ref|NP_191433.1| citrate synthase, glyoxysomal, putative [Arabidopsis thaliana]
pir||T49157 citrate synthase-like protein - Arabidopsis thaliana
(480 aa)

Score: 89 bits (221), Expect: 1.80632e-16
Length: 400, Idn/Pos/Gap = 101/175/49 (25%/43%/12%)

Query:  92 SLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQD 150
           S +D  EGI R+RG+ + E            E+     + +LL+ G +P++ Q+      
Sbjct: 107 SYIDGDEGILRYRGYPVEEL----------AEKSTYTEVTYLLIYGNLPSQRQLADWEFA 156

Query: 151 LKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCL 210
           + + +AVP  VL ++  +P++ +HP+     A+S L      A     G       +   
Sbjct: 157 ISQNSAVPQGVLDMIQSMPND-VHPVGALVTAMSALSIFYPDANPSLMGLGVYKSKQVRD 215

Query: 211 EDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLG---FELN-EFDE 266
           +  + ++ + P +AA  Y          P   +   ++  + +  S+G   ++ N     
Sbjct: 216 KQIVRVLGQAPTIAAAAYLRKAGKPPVQPLSNLSYSENF-LYMVESMGDRSYKPNPRLAR 274

Query: 267 LMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLL 326
           ++ +  +L A+HE  N S  A R + S+  D Y + + G+  + GPLHG A +  +  L 
Sbjct: 275 VLDILFILQAEHEM-NCSTAAARHLSSSGGDVYTAVSGGVGAIYGPLHGGAVEATINMLS 333

Query: 327 QMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDE 386
           ++         T EN+ E       +   + GFGH + +  DPR    ++ A      DE
Sbjct: 334 EIG--------TVENIPEFIESVKNKKRRLSGFGHRIYKNYDPRGKVVKKLA------DE 379

Query: 387 MFQLVSK--LYEV----VPRVLEEQGKVKNP-WPNVDQHSGILLRYYGLVESNFYTVLFG 439
           +F ++ +  L EV        L ++  VK   +PNVD +SG++ R  G+  S        
Sbjct: 380 VFSILGRDPLVEVGDALEKAALSDEYFVKRKLYPNVDFYSGLINRAMGIPSS-----FTA 434

Query: 440 VSRALGTLSSLVWDRALGLP---IERPKSVTTQWIREHFE 476
           VSR  G LS   W  +L  P   I RP+ V T     H+E
Sbjct: 435 VSRIAGYLSH--WRESLDDPDTKIMRPQQVYTGAGIRHYE 472


gb|AAB82405.1| citrate synthase [Sinorhizobium meliloti]
(429 aa)

Score: 89 bits (221), Expect: 1.85211e-16
Length: 406, Idn/Pos/Gap = 104/177/56 (25%/43%/13%)

Query:  80 GMRSLKAMVYETSLLDPQEGIRF-RGFSIPECQRLLPRAKPSGEQPLPEG----LLWLLL 134
           G  S  +   + + +D  EG+   RGF I              EQ    G    + +LLL
Sbjct:  46 GFTSTASCESKITYIDGDEGVLLHRGFPI--------------EQLAEHGDFLEVCYLLL  91

Query: 135 TGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAE 194
            GE+PT++Q       +     V  ++ R       +  HPM      V  L        
Sbjct:  92 YGELPTKAQKADFDYRVTHHTMVHEQMSRFFTGFRRD-AHPMAVMCGCVGALS------- 143

Query: 195 AYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHV--PAEKIEKVDDMGMR 252
           A+   +   T     +  +L +IA++P +AA  Y+  +H G+    P   ++   +  +R
Sbjct: 144 AFYHDSTDITDPHQRMVASLRMIAKMPTIAAMAYK--YHIGQPFVYPKNDLDYASNF-LR 200

Query: 253 LARSLGFE---LNE-FDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNG 308
           +  ++  E   +N      M    +LHA+HE  N S   VRL GS+ ++P+   AAG+  
Sbjct: 201 MCFAVPCEDYVVNPVLARAMDRIFILHANHEQ-NASTSTVRLAGSSGANPFACIAAGIAC 259

Query: 309 LAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTD 368
           L GP HG AN+      L M  ++G      E + +   +   +   + GFGH V +  D
Sbjct: 260 LWGPAHGGANEAA----LNMLAEIGTADRIPEYIAKA--KDKNDPFRLMGFGHRVYKNYD 313

Query: 369 PRYTAQREFA---LKHLPH--DEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILL 423
           PR    ++     L  L H  D + ++  +L  +   + +E    K  +PN+D +SGI L
Sbjct: 314 PRAKIMQKTTHEVLAELGHKDDPLLEVAMELERIA--LTDEYFVEKKLYPNIDFYSGITL 371

Query: 424 RYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPKSV 466
           +  G   +  +TVLF ++R +G ++   W+  +  P   I RP+ +
Sbjct: 372 KALGF-PTTMFTVLFALARTVGWIAQ--WNEMIEDPEQRIGRPRQL 414


emb|CAD15693.1| PROBABLE CITRATE SYNTHASE PROTEIN [Ralstonia solanacearum]
ref|NP_520112.1| PROBABLE CITRATE SYNTHASE PROTEIN [Ralstonia solanacearum GMI1000]
(433 aa)

Score: 89 bits (221), Expect: 1.93101e-16
Length: 351, Idn/Pos/Gap = 98/165/35 (27%/47%/9%)

Query: 129 LLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQH 188
           + +LLL GE+P   Q +     +     V  ++   L     +  HPM   +  V     
Sbjct:  90 ICYLLLKGELPNAKQKDEFNSTVMNHTMVHEQMQFFLRGFRRD-AHPMAVLTGLVG---- 144

Query: 189 ESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDD 248
              M+  Y   A  +   E  +   + LIA+LP + A  Y+         P   +    +
Sbjct: 145 --AMSAFYPDAANINDSREREISQ-IRLIAKLPTLVAMAYKYNIGQPLIYPQNNLSYTGN 201

Query: 249 -MGMRLARSL-GFELNEFDE--LMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAA 304
            M M  A     +++N   E  L R++ +LHADHE  N S   VRL GS+ ++P  + AA
Sbjct: 202 FMRMMFATPCEDYKVNPVLERALDRIF-ILHADHEQ-NASTSTVRLAGSSGTNPIAAIAA 259

Query: 305 GLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVL 364
           G+  L GP HG AN+      L M E++G+     E ++++  +    G  + GFGH V 
Sbjct: 260 GIACLWGPAHGGANEAA----LNMLEEIGSVDKIDEFIKQV--KDKNSGVRLMGFGHRVY 313

Query: 365 RRTDPRYTAQREFALK-----HLPHDEMFQLVSKLYEVVPRVLEEQGKV-KNPWPNVDQH 418
           +  DPR    RE   +      L +D +F+L   L ++    LE++  V +  +PNVD +
Sbjct: 314 KNYDPRAKLMRETCHEVLQELGLENDRLFKLAMALEKI---ALEDEYFVSRKLYPNVDFY 370

Query: 419 SGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPKSV 466
           SGI+ R  G + ++ +T +F ++R++G ++   W+  +  P   I RP+ +
Sbjct: 371 SGIVQRALG-IPTSMFTCIFALARSVGWIAQ--WEEMITDPEYKIGRPRQL 418


ref|YP_160848.1| citrate synthase [Azoarcus sp. EbN1]
emb|CAI09947.1| Citrate synthase [Azoarcus sp. EbN1]
(431 aa)

Score: 89 bits (221), Expect: 1.97996e-16
Length: 348, Idn/Pos/Gap = 90/153/33 (25%/43%/9%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LL  GE+P  +Q       +K    +  ++ +       +  HPM      V  L    
Sbjct:  89 YLLKNGELPNGTQKVEFENTIKNHTMLHDQMTKFFTGFRRD-AHPMAVMVGVVGALS--- 144

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMG 250
               A+   A   +  E+       LIA+LP + A  Y+         P  +++   +  
Sbjct: 145 ----AFYHEAMDFSDSEHRNISINRLIAKLPTIVAMAYKYNMGQPFMYPRNELDYTANFM 200

Query: 251 MRLARSLGFELNEFDELMRLY---LVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLN 307
             +  +   E      L+R       LHADHE  N S   VRL GS+ ++P+   +AG+ 
Sbjct: 201 HMMFGTPCEEYKPNPVLVRALDTIFTLHADHEQ-NASTSTVRLAGSSGANPFACISAGIA 259

Query: 308 GLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRT 367
            L GP HG AN+      L M E++G+     E +     +   +   + GFGH V +  
Sbjct: 260 CLWGPAHGGANEAC----LNMLEEIGDVSRVGEYIARA--KDKNDSFKLMGFGHRVYKNF 313

Query: 368 DPRYTAQREFALK-----HLPHDEMFQLVSKLYEVVPRVLEEQGKV-KNPWPNVDQHSGI 421
           DPR    R+          L +D +F+L  +L ++    LE+Q  V K  +PNVD +SGI
Sbjct: 314 DPRAKLMRQVCYDVLGELGLENDRLFKLAMELEKI---ALEDQYFVEKKLYPNVDFYSGI 370

Query: 422 LLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPKSV 466
           + +  G + ++ +T +F ++R +G ++   W+  +  P   I RP+ +
Sbjct: 371 VQKALG-IPTSMFTCIFALARTVGWITQ--WEEMITDPEYKIGRPRQL 415


gb|AAB02956.1| citrate synthase [Rickettsia bellii]
sp|Q59734|CISY_RICBE Citrate synthase
(412 aa)

Score: 89 bits (220), Expect: 2.03014e-16
Length: 429, Idn/Pos/Gap = 104/187/59 (24%/43%/13%)

Query:  60 VRERFGEEVLDACTVNQAYG---------GMRSLKAMVYETSLLDPQEGI-RFRGFSIPE 109
           ++   G++V+D   +++ Y          G  S  +     + +D  +GI R RG+ I  
Sbjct:  19 LKASIGQDVID---ISKVYSEADCFTYDPGFMSTASCRSTITYIDGDQGILRHRGYDI--  73

Query: 110 CQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELP 169
                   K   E+     + +LL+ GE+P   Q     + +   A V  E L  L +  
Sbjct:  74 --------KDLAEKSDFLEVAYLLIYGELPNNKQYNDFTKKVAHHALVN-ERLHYLFQTF 124

Query: 170 HERMHPMTQFSVAV-SLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIY 228
               HPM     AV SL      +   + +   + T        A+ +IA++P +AA  Y
Sbjct: 125 CSSSHPMAIMLAAVGSLSAFYPDLLNFFKEADYELT--------AIRMIAKIPTIAAMSY 176

Query: 229 RNTFHGGKHVPAEKIEKVDD-MGMRLARSL-GFELNEF--DELMRLYLVLHADHEGGNVS 284
           + +       P   ++  ++ + M  A     +++N    + L +++ +LHADHE  N S
Sbjct: 177 KYSIGQPFVYPDNSLDFTENFLHMMFATPCEKYKVNPVIKNALNKIF-ILHADHEQ-NAS 234

Query: 285 AHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRE 344
              VR+ GS+ ++P+   + G+  L GP HG AN+ V+  L ++   + N P      ++
Sbjct: 235 TSTVRIAGSSGANPFACVSTGIASLWGPAHGGANEAVINMLKEIGS-VENIPKYIAKAKD 293

Query: 345 LCWETLREGHVIPGFGHAVLRRTDPRYTAQREFA------LKHLPHDEMFQLVSKLYEVV 398
                  +   + GFGH V +  DPR    +E        L  L ++ + Q+  +L  + 
Sbjct: 294 -----KNDNFRLMGFGHRVYKNYDPRAAVLKETCKEVLKELGQLDNNPLLQIAIELEAIA 348

Query: 399 PRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGL 458
            +  +E    +  +PNVD +SGI+ +  G +    +TVLF  +R +G ++   W      
Sbjct: 349 LK--DEYFIERKLYPNVDFYSGIIYKAMG-IPPQMFTVLFATARTVGWMAQ--WKEMHED 403

Query: 459 P---IERPK 464
           P   I RP+
Sbjct: 404 PEQKISRPR 412


gb|AAB02955.1| citrate synthase [Rickettsia africae]
sp|Q59732|CISY_RICAF Citrate synthase
(411 aa)

Score: 89 bits (220), Expect: 2.03014e-16
Length: 433, Idn/Pos/Gap = 103/189/68 (23%/43%/15%)

Query:  60 VRERFGEEVLDACTVNQAYG------GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQR 112
           ++   GE+V+D   V+          G  S  +     + +D  +GI R RG+ I     
Sbjct:  19 LKASIGEDVIDISRVSAEADCFTYDPGFMSTASCQSTITYIDGDKGILRHRGYDI-----  73

Query: 113 LLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHER 172
                K   E+     + +LL+ GE+P+  Q  +  + +   + V            +ER
Sbjct:  74 -----KDLAEKSDFLEVAYLLIYGELPSGEQYNNFTKQVAHHSLV------------NER 116

Query: 173 MHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLE--------DALTLIARLPAVA 224
           +H + Q     +       MA   A     S F+   L          A+ +IA++P +A
Sbjct: 117 LHYLFQ-----TFCSSSHPMAIMLAAVGSLSAFYPDLLNFKEADYELTAIRMIAKIPTIA 171

Query: 225 ARIYRNTFHGGKHVPAEKIEKVDD-MGMRLARS-LGFELNEF--DELMRLYLVLHADHEG 280
           A  Y+ +       P   ++  ++ + M  A     + +N    + L +++ +LHADHE 
Sbjct: 172 AMSYKYSIGQPFIYPDNPLDFTENFLHMMFATPCTKYTVNPIIKNALNKIF-ILHADHEQ 230

Query: 281 GNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTE 340
            N S   VR+ GS+ ++P+   + G+  L GP HG AN+ V    + M +++G+     +
Sbjct: 231 -NASTSTVRIAGSSGANPFACISTGIASLWGPAHGGANEAV----INMLKEIGSSEYIPK 285

Query: 341 NLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFA------LKHLPHDEMFQLVSKL 394
            + +   +   +   + GFGH V +  DPR    +E        L  L ++ + Q+  +L
Sbjct: 286 YIAKA--KDKNDPFRLMGFGHRVYKNYDPRAAVLKETCKEVLKELGQLDNNPLLQIAIEL 343

Query: 395 YEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDR 454
             +  +  +E    +  +PNVD +SGI+ +  G + S  +TVLF ++R +G ++   W  
Sbjct: 344 EAIALK--DEYFIERKLYPNVDFYSGIIYKAMG-IPSQMFTVLFVIARTVGWMAQ--WKE 398

Query: 455 ALGLP---IERPK 464
               P   I RP+
Sbjct: 399 MHEDPEQKISRPR 411


ref|NP_925958.1| citrate synthase [Gloeobacter violaceus PCC 7421]
dbj|BAC90953.1| citrate synthase [Gloeobacter violaceus PCC 7421]
(380 aa)

Score: 89 bits (220), Expect: 2.13436e-16
Length: 354, Idn/Pos/Gap = 98/154/55 (27%/43%/15%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLL---- 186
           +LL+   +PT+ ++ S   ++     V   +  ++   P E   PM      ++ L    
Sbjct:  50 FLLIFDHLPTKDELLSFEVEILGHRRVKYRIRDMIKSFP-ESGRPMVALQSCIAALGLFY 108

Query: 187 --QHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIE 244
             Q+ESK   AY              +  + L+A++P + A     TFH  + +  + I 
Sbjct: 109 PLQNESKEKYAY--------------DSTIRLLAKMPTMVA-----TFHQMR-LGNDPIP 148

Query: 245 KVDDMGMRLARSLGFELNEFD----ELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYL 300
             DD+G            E D     +  + L+LHA+H   N S  +  +  S L+DPY 
Sbjct: 149 PRDDLGHAANFLYMLTGKEPDPRAARIFDVCLMLHAEHTV-NASTFSALVTASTLADPYT 207

Query: 301 SFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFG 360
              +    L+GPLHG AN+EV+R L ++         T E +R      L     I G G
Sbjct: 208 VITSAAGTLSGPLHGGANEEVIRMLKEIG--------TIERVRPYLENRLARKEKIMGVG 259

Query: 361 HAVLRRTDPRYTAQREFALKHLPHDEMFQLV--SKLYEV---VPRVLEEQGKVKNPWPNV 415
           H V +  DPR T  +  A       E+F     S+LY++   V RV +E    K  +PNV
Sbjct: 260 HRVYKVKDPRATILQNLA------QELFDRFGHSRLYDIAVEVERVCDELLGQKGIYPNV 313

Query: 416 DQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALG-LPIERPKSVTT 468
           D +SG++    G + ++ +T +F +SR  G L+   W   L    I RP  V T
Sbjct: 314 DFYSGLVYEKMG-IPADMFTPVFAISRVAGWLAH--WHEQLADNRIFRPTQVYT 364


gb|AAB02966.1| citrate synthase [Rickettsia sp.]
(411 aa)

Score: 89 bits (220), Expect: 2.15225e-16
Length: 435, Idn/Pos/Gap = 106/192/72 (24%/44%/16%)

Query:  60 VRERFGEEVLDACTVNQAYG------GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQR 112
           ++   GE+V+D   V+          G  S  +     + +D  +GI R+RG+ I     
Sbjct:  19 LKASIGEDVIDISRVSAEADCFTYDPGFMSTASCRSTITYIDGDKGILRYRGYDI-----  73

Query: 113 LLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHER 172
                K   E+     + +LL+ GE+P+  Q      +  ++ AV          L +ER
Sbjct:  74 -----KDLAEKSDFLEVAYLLIYGELPSSEQY----NNFTKKVAV--------HSLVNER 116

Query: 173 MHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLE--------DALTLIARLPAVA 224
           +H + Q     +       MA   A     S F+   L          A+ +IA++P +A
Sbjct: 117 LHYLFQ-----TFCSSSHPMAIMLAAVGSLSAFYPDLLNFKEADYELTAIRMIAKIPTIA 171

Query: 225 ARIYRNTFHGGKHVPAEKIEKVDD-MGMRLARSL-GFELNEF--DELMRLYLVLHADHEG 280
           A  Y+ +       P   ++  ++ + M  A     +++N    + L +++ +LHADHE 
Sbjct: 172 AMSYKYSIGQPFIYPDNALDFTENFLHMMFATPCEKYKVNPIIKNALNKIF-ILHADHEQ 230

Query: 281 GNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTE 340
            N S   VR+ GS+ ++P+   + G+  L GP HG AN+ V    + M +++G    ++E
Sbjct: 231 -NASTSTVRIAGSSGANPFACVSTGIASLWGPAHGGANEAV----INMLKEIG----SSE 281

Query: 341 NLRELCWETLREGHV--IPGFGHAVLRRTDPRYTAQREFA------LKHLPHDEMFQLVS 392
           N+ +   +   +     + GFGH V +  D R    +E        L  L  + + Q+  
Sbjct: 282 NIPKYIAKAKDKNDPFRLMGFGHRVYKNYDLRAAVLKETCKEVLKELGQLDGNPLLQIAI 341

Query: 393 KLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVW 452
           +L  +  +  +E    +  +PNVD +SGI+ +  G + S  +TVLF ++R +G ++   W
Sbjct: 342 ELEAIALK--DEYFIERKLYPNVDFYSGIIYKAMG-IPSQMFTVLFAIARTVGWMAQ--W 396

Query: 453 DRALGLP---IERPK 464
                 P   I RP+
Sbjct: 397 KEMHEDPEQKISRPR 411


ref|NP_662713.1| citrate synthase [Chlorobium tepidum TLS]
gb|AAM73055.1| citrate synthase [Chlorobium tepidum TLS]
(447 aa)

Score: 89 bits (220), Expect: 2.15225e-16
Length: 389, Idn/Pos/Gap = 97/172/50 (24%/44%/12%)

Query:  92 SLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQD 150
           + +D  +GI R+RG+ I +            E+       +LL+ GE+P + ++     +
Sbjct:  65 TFIDGDKGILRYRGYPIEQL----------AEKSSFLETAYLLIKGELPDKERLAVWTYN 114

Query: 151 LKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKM-AEAYAQGAPKSTFWEYC 209
           ++        + + +D   ++  HPM    + V  L   S    +A   G  +S   +  
Sbjct: 115 IRHHTMTHANLTKFMDGFRYD-AHPM---GILVGTLGALSTFYPDAKNVGEEESRKLQ-- 168

Query: 210 LEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNE------ 263
                 LI ++P +AA  +R++      +P   +    +       S+ F + E      
Sbjct: 169 ---VRRLIGKMPTLAAMSFRHSLGFPYVLPDNDLSYAGNF-----LSMMFRMTEKNYKPN 220

Query: 264 --FDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEV 321
              +  + +  +LHADHE  N S +AVR V S++ DPY + AAG   L GPLHG AN+ V
Sbjct: 221 PVLEHALDVLFILHADHEQ-NCSTNAVRSVSSSMVDPYSAIAAGCAALYGPLHGGANEAV 279

Query: 322 LRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKH 381
               + M +++G+     E ++ +      EG ++ GFGH V +  DPR    ++ A   
Sbjct: 280 ----IHMLKQIGSVDKIPEFIKLV---KSGEGRLM-GFGHRVYKNYDPRARIIKKIAFDV 331

Query: 382 LPHDEMFQLVSKLYEVVPRVLEEQGKVKNP-WPNVDQHSGILLRYYGLVESNFYTVLFGV 440
                   L+    E+    LE+   ++   +PNVD +SG++ +  G   +  + VLF +
Sbjct: 332 FEETGRNPLLDIAIELERIALEDDYFIQRKLYPNVDFYSGLIYQAMGF-PTEMFPVLFAI 390

Query: 441 SRALGTLSSLVWDRALGLP---IERPKSV 466
            R  G L+   W   +  P   I RP+ +
Sbjct: 391 GRTPGWLAQ--WIEHVKDPEQKIARPRQI 417


gb|AAB02965.1| citrate synthase [Rickettsia rickettsii]
(410 aa)

Score: 89 bits (220), Expect: 2.33953e-16
Length: 424, Idn/Pos/Gap = 106/189/51 (25%/44%/12%)

Query:  60 VRERFGEEVLDACTVNQAYG------GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQR 112
           ++   GE+V+D   V+          G  S  +     + +D  +GI R RG+ I     
Sbjct:  19 LKASIGEDVIDISRVSAEADCFTYDPGFMSTASCQSTITYIDGDKGILRHRGYDI-----  73

Query: 113 LLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHER 172
                K   E+     + +LL+ GE+P+  Q  +  + +   + V  E L  L +     
Sbjct:  74 -----KDLAEKSDFLEVAYLLIYGELPSGEQYNNFTKQVAHHSLVN-ERLHYLFQTFCSS 127

Query: 173 MHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTF 232
            HPM     AV  L        A+          +Y L  A+ +IA++P +AA  Y+ + 
Sbjct: 128 SHPMAIMLAAVGSLA-------AFYPDLLNFKEADYELT-AIRMIAKIPTIAAMSYKYSI 179

Query: 233 HGGKHVPAEKIEKVDD-MGMRLARS-LGFELNEF--DELMRLYLVLHADHEGGNVSAHAV 288
                 P   ++  ++ + M  A     + +N    + L +++ +LHADHE  N S   V
Sbjct: 180 GQPFIYPDNSLDFTENFLHMMFATPCTKYTVNPIIKNALNKIF-ILHADHEQ-NASTSTV 237

Query: 289 RLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWE 348
           R+ GS+ ++P+   + G+  L GP HG AN+ V    + M +++G+     + + +   +
Sbjct: 238 RIAGSSGANPFACISTGIASLWGPAHGGANEAV----INMLKEIGSSEYIPKYIAKA--K 291

Query: 349 TLREGHVIPGFGHAVLRRTDPRYTAQREF---ALKHLPH--DEMFQLVSKLYEVVPRVLE 403
              +   + GFGH V +  DPR    +E     LK L    + + Q+  +L  +  +  +
Sbjct: 292 DKNDPFRLMGFGHRVYKNYDPRAVVLKETCKEVLKELGQLDNNLLQIAIELEAIALK--D 349

Query: 404 EQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---I 460
           E    +  +PNVD +SGI+ +  G + S  +TVLF ++R +G ++   W      P   I
Sbjct: 350 EYFIERKLYPNVDFYSGIIYKAMG-IPSQMFTVLFAIARTVGWMAQ--WKEMHEDPEQKI 406

Query: 461 ERPK 464
            RP+
Sbjct: 407 SRPR 410


emb|CAE08790.1| citrate synthase [Synechococcus sp. WH 8102]
ref|NP_898364.1| citrate synthase [Synechococcus sp. WH 8102]
(396 aa)

Score: 89 bits (220), Expect: 2.33953e-16
Length: 345, Idn/Pos/Gap = 100/151/41 (28%/43%/11%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQF-SVAVSLLQHE 189
           +LL+ GE+P+  Q+      ++    V   V  ++   P    HPM    S A SL    
Sbjct:  63 FLLIWGELPSRDQLAEFEHAVQMHRRVSFRVRDMMKCFPASG-HPMDALQSSAASLGLFY 121

Query: 190 SKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDM 249
           S+ A    Q         Y  +  + LIA++P + A         G+    + I+  DD+
Sbjct: 122 SRRAIDDPQ---------YVYDAVVRLIAKIPTMVAAF--QLIRKGQ----DPIQPRDDL 166

Query: 250 GMRLARSLGFELNEFDELM-RLY---LVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAG 305
                        E D L  R++   L+LHA+H   N S  + R+  S L+DPY   A+ 
Sbjct: 167 AYSANFLYMLTEREPDPLAARIFDRCLMLHAEHSL-NASTFSARVTASTLTDPYAVVASA 225

Query: 306 LNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLR 365
           +  LAGPLHG AN++V    L M E++G    T EN      E +     I GFGH   +
Sbjct: 226 VGTLAGPLHGGANEDV----LAMLEEVG----TAENAGAYLDEAMAAKRKIMGFGHREYK 277

Query: 366 RTDPR---YTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGIL 422
             DPR     A  E       HDE++ +       + R  E +   K  +PNVD +SG++
Sbjct: 278 VKDPRAVILQALVEEMFARFGHDELYDVAV----AIEREAESRLGPKGIYPNVDFYSGLV 333

Query: 423 LRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP-IERPKSV 466
            R  G +  + +T +F ++R  G L+   W   LG   I RP  +
Sbjct: 334 YRKLG-IPRDLFTPVFAIARVAGWLAH--WREQLGANRIFRPSQI 375


ref|YP_033467.1| Citrate synthase [Bartonella henselae str. Houston-1]
emb|CAF27442.1| Citrate synthase [Bartonella henselae str. Houston-1]
pir||I40044 citrate (si)-synthase (EC 4.1.3.7) - Bartonella henselae
gb|AAA87325.1| citrate synthase
sp|P51033|CISY_BARHE Citrate synthase
(431 aa)

Score: 89 bits (220), Expect: 2.3789e-16
Length: 352, Idn/Pos/Gap = 92/163/33 (26%/46%/9%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LLL GE+PT+ +     + + +   V  +  R       +  HPM   +V ++ L   S
Sbjct:  88 YLLLYGELPTKQEKIDFDRCIMQHTMVHEQFARFFHGFRRDS-HPM---AVMIACLGAMS 143

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMG 250
               A+   +   T  +  +  ++ LI+++P +AA  Y+ +       P   +    +  
Sbjct: 144 ----AFYHDSIDITDPQQRMIASIRLISKVPTLAAMAYKYSIGQAFVYPRNDLSYAANF- 198

Query: 251 MRLARSLGFELNEFDEL----MRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGL 306
           +R+  S+  E  + + +    M     LHADHE  N S   VRL GS+ ++P+   AAG+
Sbjct: 199 LRMCFSVPCEEYKINPVLTRAMDRIFTLHADHEQ-NASTSTVRLAGSSGANPFACIAAGV 257

Query: 307 NGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRR 366
             L GP HG AN+  L+    M +++G+     E +     +   +   + GFGH V + 
Sbjct: 258 ACLWGPAHGGANEACLK----MLQEIGSVERIPEFIARA--KDKNDSFRLMGFGHRVYKN 311

Query: 367 TDPRYTAQREF---ALKHL--PHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGI 421
            DPR    ++     LK L   +D +  +   L  +   + +E    K  +PNVD +SGI
Sbjct: 312 YDPRAKIMQQTCHEVLKELNIQNDPLLDIAITLENIA--LNDEYFIEKKLYPNVDFYSGI 369

Query: 422 LLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPKSVTTQW 470
            L+  G   +  +TVLF ++R++G ++   W   +  P   I RP+ + T +
Sbjct: 370 TLKALGF-PTEMFTVLFALARSVGWVAQ--WKEMIEDPAQKISRPRQLYTGY 418


ref|YP_083702.1| citrate synthase [Bacillus cereus ZK]
gb|AAU18147.1| citrate synthase [Bacillus cereus ZK]
(372 aa)

Score: 89 bits (220), Expect: 2.48024e-16
Length: 323, Idn/Pos/Gap = 90/147/30 (27%/45%/9%)

Query: 132 LLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESK 191
           LLL   +P E +  ++ + LK   AVP  V  +L  LP E  HPM      VS L     
Sbjct:  53 LLLEEHLPNEDEKATLEKKLKEEYAVPEGVFNVLKALPKE-THPMDGLRTGVSALAGYDN 111

Query: 192 MAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFH-GGKHVPAEKIEKVDDMG 250
             E  +    KS  ++        L++++P + A    N++H      P E +E++    
Sbjct: 112 DIENRSLEVNKSRGYK--------LLSKVPNIVA----NSYHILNNEDPIEPLEELSYSA 159

Query: 251 MRLARSLGFELNEFDE-LMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGL 309
                  G +  E +E +    LVL+++HE  N S    R++ S  SD Y +    +  L
Sbjct: 160 NFFYMLTGKKPTELEEKIFDRSLVLYSEHEMPN-STFTARVIASTQSDLYGALTGAVASL 218

Query: 310 AGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAV-LRRTD 368
            G LHG AN+ V+  LL+     GN     E   EL  + L     I GFGH V +++ D
Sbjct: 219 KGSLHGGANEAVMYMLLEA----GN----VEKFEELLQKKLYNKEKIMGFGHRVYMKKMD 270

Query: 369 PRYTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGL 428
           PR    +E ALK L   +    + ++ E   +++E++   K  +PN+D ++  +    G 
Sbjct: 271 PRALMMKE-ALKQLCDVKGDYTLYEMCEAGEKIMEKE---KGIYPNLDYYAAPVYWMLG- 325

Query: 429 VESNFYTVLFGVSRALGTLSSLV 451
           +    YT +F  SR +G  + ++
Sbjct: 326 IPIQLYTPIFFSSRTVGLCAHVI 348


gb|AAL01667.1| citrate synthase [Neorickettsia helminthoeca]
(403 aa)

Score: 89 bits (220), Expect: 2.54311e-16
Length: 365, Idn/Pos/Gap = 90/160/45 (24%/43%/12%)

Query:  90 ETSLLDPQEGIR-FRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVC 148
           E + +D +EG+  +RG+ + E        +          +++LLL GE+P   + +   
Sbjct:  47 EITFVDGEEGVLLYRGYPVDELATQCDFLR----------VVYLLLYGELPDPVRAKEFR  96

Query: 149 QDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQ--HESKMAEAYAQGAPKSTFW 206
             ++    +P  VL  +   P +  HPM     A + L   H     E + +        
Sbjct:  97 TFIQNFPQLPDCVLENICSFPRD-AHPMVILISAFAALASAHHDSDFETHKE-------- 147

Query: 207 EYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDE 266
                    LIA +P + A IYR        +P +    +  +G       G +  +++ 
Sbjct: 148 --------VLIANVPRLVAYIYR-YITSQDFIPPDAC--LSYVGNFFYMMFGEKKPDYES 196

Query: 267 LMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLL 326
           ++   L+LHADHE  N S    R+V S+ + P  + +A    L GPLHG AN++VL  L 
Sbjct: 197 ILDKILILHADHEQ-NASTSTARMVVSSGASPIAAVSAATATLWGPLHGGANEKVLHMLG 255

Query: 327 QMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLP-HD 385
           +++++ G       ++ E      R+   + GFGH V +  DPR    +  A   L    
Sbjct: 256 EIEKQGG-------SVEEFIERVKRKEERLMGFGHRVYKNYDPRAVILKSTAQDILKGSS 308

Query: 386 EMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALG 445
            +  + SKL  +     +E    +  +PNVD +SGI+L   G + +  +T +F ++R  G
Sbjct: 309 SILSIASKLESIASN--DEYFISRKLYPNVDFYSGIILNALG-IPTYMFTPIFALARTSG 365

Query: 446 TLSSL 450
            ++ +
Sbjct: 366 WVAQI 370


ref|ZP_00329333.1| COG0372: Citrate synthase [Moorella thermoacetica ATCC 39073]
(448 aa)

Score: 89 bits (220), Expect: 2.54311e-16
Length: 354, Idn/Pos/Gap = 95/156/31 (26%/44%/8%)

Query: 127 EGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLR--LLDELPHERMHPMTQFSVAVS 184
           E + +LLL GE+P + ++E     L    ++P   +   +L    ++ M+ + +      
Sbjct:  92 EEVCYLLLFGELPDKKRLEEFTHLLAEHRSLPDGFVEDMILKAPSNDIMNKLAR------ 145

Query: 185 LLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGK------HV 238
                S +A       P        L   + LIAR P + A  Y+   H  +      H+
Sbjct: 146 -----SVLAAYSYDPNPDDISIRNVLRQCIELIARFPIMVAYGYQAKAHYYENKSLYIHL 200

Query: 239 PAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDP 298
           P  ++   ++  + + R      +   EL+ L LVLHA+H GGN SA  V +V S  +D 
Sbjct: 201 PQTELSTAENF-LYMIRPDNQYTSLEAELLDLALVLHAEHGGGNNSAFTVHVVSSTGTDT 259

Query: 299 YLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLRE-----G 353
           Y   AA    L GP HG AN +V++ +  +K  + +     E LR    + LR+      
Sbjct: 260 YSVIAAATGSLKGPKHGGANIKVMKMIEDIKNNVKDW-HDEEELRNYLIKILRKEAFDRS 318

Query: 354 HVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEM---FQLVSKLYEVVPRVLEEQGKV-K 409
            +I G GHAV   +DPR    ++ A +     +M   F L   + ++ P +   + KV K
Sbjct: 319 GLIYGIGHAVYTLSDPRAVLLKQKAAELAREKDMEDEFGLYLAIEKMAPELFVAEKKVDK 378

Query: 410 NPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLPIERP 463
              PNVD +SG + +    +    YT +F +SR  G  +  + +   G  I RP
Sbjct: 379 VVAPNVDFYSGFVYKMLN-IPIELYTPIFAISRIAGWCAHRIEELVSGGKIFRP 431


ref|ZP_00307000.1| COG0372: Citrate synthase [Ferroplasma acidarmanus]
(374 aa)

Score: 88 bits (219), Expect: 2.62942e-16
Length: 394, Idn/Pos/Gap = 105/162/50 (26%/41%/12%)

Query:  92 SLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQD 150
           + +D   G+ R+RG+ I +        + +G     E + +L+  GE+P   Q+    + 
Sbjct:  18 TFIDGNAGVLRYRGYDINDL------VQNTGF----EEVCYLMTNGELPNSQQLAEFKKS  67

Query: 151 LKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFW--EY 208
           +K    +P  V+ L+ +LP E          A +L    + M  A+A  +     W  E 
Sbjct:  68 VKEHYKLPDHVMELISDLPRE----------ADTL----TMMETAFASLSSGDYQWNKEN 113

Query: 209 CLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELM 268
             +    ++     + + IYR+    G   P  K +  +     L    G    +    M
Sbjct: 114 DRKQVPKILGENLGIISNIYRHKMGMGLQNPDPKYDYAEAF---LRNCFGNADEKKISAM 170

Query: 269 RLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQM 328
              LV++ DHE    S  A  +  S LSD Y    A    L GPLHG A +   + LL  
Sbjct: 171 NAALVIYVDHE-VPASTTAALVASSTLSDMYSCITAATAALKGPLHGGAAEAAYKQLLD- 228

Query: 329 KEKLGNRPMTTENLRELCWETLREG-HVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEM 387
              +GN     +N+       + +G   + GFGH V R  DPR    ++ A      DE 
Sbjct: 229 ---IGN----VDNVENWFKTNILDGKRRLMGFGHRVYRTYDPRMKIFKKLATTLEQTDEQ 281

Query: 388 FQLVSKLYEVVPRVLEEQGKV----KNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRA 443
                KL+E+  + LEE G      K  +PN D +SGI+    G      +T LFG SR 
Sbjct: 282 ----KKLFEIAVK-LEELGVKEFGGKGIYPNTDYYSGIVFNEIGF-PIYMFTTLFGFSRV 335

Query: 444 LGTLSSLVWDRALGLPIERPKSVTTQWIREHFEK 477
           LG LS +         + RP++V T   +  F K
Sbjct: 336 LGWLSHITEYVEEEERLIRPRAVYTGPDKRDFVK 369


ref|ZP_00269153.1| COG0372: Citrate synthase [Rhodospirillum rubrum]
(433 aa)

Score: 88 bits (219), Expect: 2.78756e-16
Length: 356, Idn/Pos/Gap = 95/160/31 (26%/44%/8%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LLL GE+PT  +     + +     V  ++ +  D    +  HPM      V  L    
Sbjct:  92 YLLLRGELPTAPKKTEFEKIITYHTMVHEQLHKFYDGFRRD-AHPMAVMCGVVGALS--- 147

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMG 250
               A+   +   T     +     L+A++P +AA  Y+ +       P   +   ++  
Sbjct: 148 ----AFYHDSIDITDPIQRMIAQHRLVAKMPTIAAWAYKYSQGQPFMYPRNNLTYAENFL 203

Query: 251 MRLARSLGFELNEFDELMRLY---LVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLN 307
             +  +   E      L R     L+LHADHE  N S   VRL GS+ ++P+   AAG+ 
Sbjct: 204 HMMFATPCEEYKVSPVLARAMDRILILHADHEQ-NASTSTVRLAGSSGANPFACIAAGIA 262

Query: 308 GLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRT 367
            L GP HG AN+ VL+ L +    +G+     + +++   +   +   + GFGH V +  
Sbjct: 263 SLWGPAHGGANEAVLKMLTE----IGSPDRVDDFVKKA--KDKNDPFRLMGFGHRVYKNY 316

Query: 368 DPRYTAQREFALKHLPHDEMFQLVSKLYEVVPRV----LEEQGKV-KNPWPNVDQHSGIL 422
           DPR  A+   A  H   DE+  +   L E+  R+    LE++  + K  +PNVD +SGI+
Sbjct: 317 DPR--AKIMAATCHEVLDELGIVDEPLLEIAMRLEKIALEDEYFIEKKLYPNVDFYSGII 374

Query: 423 LRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPKSVTTQWIREHF 475
            R  G + ++ +T LF ++R +G +S   W   +  P   I RP+ +     +  F
Sbjct: 375 FRAIG-IPTSMFTCLFALARTVGWISQ--WKEMIEDPDQKIGRPRQLYNGATKRDF 427


emb|CAA84274.1| citrate synthase [Rhizobium tropici]
pir||S41527 citrate (si)-synthase (EC 4.1.3.7) - Rhizobium tropici plasmid pMP6
sp|P51038|CISZ_RHITR Citrate synthase, plasmid
(429 aa)

Score: 88 bits (219), Expect: 2.93067e-16
Length: 352, Idn/Pos/Gap = 92/156/37 (26%/44%/10%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LLL GE+PT +Q +     +     V  ++ R       +  HPM      V  L    
Sbjct:  88 YLLLYGELPTAAQKKDFDYRVVHHTMVHEQMSRFFTGFRRD-AHPMAVMCGCVGALS--- 143

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHV--PAEKIEKVDD 248
               A+   +   T     +  +L +IA++P +AA  Y+  +H G+    P   ++   +
Sbjct: 144 ----AFYHDSTDITDPHQRMVASLRMIAKMPTLAAMAYK--YHIGQPFVYPKNDLDYASN 197

Query: 249 MGMRLARSLGFELNEFDEL----MRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAA 304
             +R+  ++  E    + +    M    +LHADHE  N S   VRL GS+ ++P+   AA
Sbjct: 198 F-LRMCFAVPCEEYVVNPVLARAMDRIFILHADHEQ-NASTSTVRLAGSSGANPFACIAA 255

Query: 305 GLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVL 364
           G+  L GP HG AN+      L M  ++G      E +     +   +   + GFGH V 
Sbjct: 256 GIACLWGPAHGGANERA----LNMLTEIGTVDRIPEYIARA--KDKNDPFRLMGFGHRVY 309

Query: 365 RRTDPRY-----TAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHS 419
           +  DPR      TA        +  D +  +  +L  +   + ++    K  +PNVD +S
Sbjct: 310 KNYDPRAKIMQKTAHEVLGELGIKDDPLLDIAIELERIA--LTDDYFIEKKLYPNVDFYS 367

Query: 420 GILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPKSVTT 468
           GI L+  G   +  +TVLF ++R +G ++   W+  +  P   I RP+ + T
Sbjct: 368 GITLKALGF-PTTMFTVLFALARTVGWIAQ--WNEMIEDPDQRIGRPRQLYT 416


ref|ZP_00132961.2| COG0372: Citrate synthase [Haemophilus somnus 2336]
(427 aa)

Score: 88 bits (219), Expect: 3.10693e-16
Length: 413, Idn/Pos/Gap = 102/182/51 (24%/44%/12%)

Query:  80 GMRSLKAMVYETSLLDPQEGIRF-RGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEI 138
           G  S  + V E + +D   GI   RG+ I +       AK +    +      LLL GE 
Sbjct:  46 GFMSTASCVSEITYIDGDNGILLHRGYPIADL------AKNADYLEVAH----LLLFGER  95

Query: 139 PTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQ 198
           P + +  +  + +K    V  ++ R       +  HPM       +++   S    A+  
Sbjct:  96 PNKEEYANFIKLVKNHTLVHEQISRFFHGFRRDS-HPM-------AIMCGVSGALAAFYH 147

Query: 199 GAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDD-MGMRLARSL 257
            +      E+    A+ L+A++P +AA  Y+ +       P  K+    + + M  A   
Sbjct: 148 DSLDINDIEHRELTAIRLLAKMPTLAAMCYKYSIGQPFMFPLNKLSYAGNFLYMMFATPC 207

Query: 258 G-FELNE-FDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHG 315
             +E+N   ++ M    +LHADHE  N S   VR   S+ ++P+   AAG+  L GP HG
Sbjct: 208 EPYEVNPVLEKAMDRIFILHADHEQ-NASTSTVRTAASSGANPFACIAAGIASLWGPAHG 266

Query: 316 LANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQR 375
            AN+      + M E++G+     E +     +   +   + GFGH V +  DPR    R
Sbjct: 267 GANEAC----INMLEEIGSVDRIPEYIARA--KDKNDPFRLMGFGHRVYKNYDPRAKVMR 320

Query: 376 EFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNP-------WPNVDQHSGILLRYYGL 428
           +   + L       + + L++V   +  E+  + +P       +PNVD +SGI+L+  G 
Sbjct: 321 QTCHEVLKE---LNIQTPLFDVAMEL--ERIALNDPYFIDHKLYPNVDFYSGIILKAIG- 374

Query: 429 VESNFYTVLFGVSRALGTLSSLVWDRAL---GLPIERPKSVTTQWIREHFEKR 478
           + ++ +TV+F ++R +G ++   W        + I RP+    Q  + H E++
Sbjct: 375 IPTSMFTVIFALARTVGWIAH--WKEMFKPGNMKIVRPR----QLYKGHTERK 421


ref|ZP_00311762.1| COG0372: Citrate synthase [Clostridium thermocellum ATCC 27405]
(456 aa)

Score: 88 bits (219), Expect: 3.15922e-16
Length: 334, Idn/Pos/Gap = 88/144/27 (26%/43%/8%)

Query: 127 EGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLR-LLDELPHERMHPMTQFSVAVSL 185
           E   +LLL G++PT  Q+    + L     +P E L  ++  LP + +  +   SV    
Sbjct:  99 EETTYLLLFGDLPTREQLNEFEKLLSSYRELPEEFLNDMILNLPGKDIMNVLARSV---- 154

Query: 186 LQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGK------HVP 239
                 +A       P  T  +  L   + LI  +P +A   Y+   H         H P
Sbjct: 155 ------LAYYTYDSNPDDTSVKNVLRQCMRLIGSMPTIAVYAYQAMAHYYDRKSLVIHPP 208

Query: 240 AEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPY 299
             ++   +++ + + R      +    L+ L LVLHA+H GGN S     +V S  +D Y
Sbjct: 209 RPELSTAENI-LHMLRPDSKYTDLEARLLDLALVLHAEHGGGNNSTFVTHVVTSTGTDTY 267

Query: 300 LSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKL----GNRPMTTENLRELCWETLREGHV 355
              AA L  L GP HG AN +V +    +K+ +     +  +    ++ L  E      +
Sbjct: 268 SVIAAALGSLKGPRHGGANIKVCQMFEDLKQNVRDWKDDEEIENYLMKLLNKEAFDRAGL 327

Query: 356 IPGFGHAVLRRTDPRYTAQREFALKHLPH---DEMFQLVSKLYEVVPRVLEEQGKV-KNP 411
           I G GHAV   +DPR    +E A K       ++ F+L  ++  + P+++    K+ K  
Sbjct: 328 IYGIGHAVYSISDPRCILLKEQAEKLAKEKGLEDEFELYDRVERLAPQIIGRVRKMYKGV 387

Query: 412 WPNVDQHSGILLRYYGLVESNFYTVLFGVSRALG 445
             NVD +SG + +   L     YT +F +SR  G
Sbjct: 388 SANVDFYSGFVYKMLNL-PLELYTPIFAISRMSG 420


ref|NP_819794.1| 2-methylcitrate synthase [Coxiella burnetii RSA 493]
gb|AAO90308.1| 2-methylcitrate synthase [Coxiella burnetii RSA 493]
(372 aa)

Score: 88 bits (219), Expect: 3.3214e-16
Length: 333, Idn/Pos/Gap = 88/150/55 (26%/45%/16%)

Query: 127 EGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLL 186
           E + +LLL  ++PT+S++++  + L    ++PP +   L+ +P    HPM       S+L
Sbjct:  45 EEVAYLLLKNKLPTKSELDAYTKKLVNLRSLPPALKDTLERIPASS-HPMDVMRTGCSML 103

Query: 187 QHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKV 246
            +            P++ F E     A  L+A  PA+    Y  + HG K +  E    +
Sbjct: 104 GNLE----------PENGF-ENEQNIADRLVAIFPAIQCYWYHYSHHG-KRIDTE----L 147

Query: 247 DDM---GMRLARSLGFELNEFD-ELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSF 302
           DD+   G  L   LG +  +   + M   L+L+A+HE  N S  A R+  + LSD Y + 
Sbjct: 148 DDLTLAGYFLHLLLGKKAAQMAIDCMNASLILYAEHEF-NASTFAARVCSATLSDIYSAV 206

Query: 303 AAGLNGLAGPLHGLANQEVLRWLL----------QMKEKLGNRPMTTENLRELCWETLRE 352
            A +  L GPLHG AN+  +  ++           +K KL N+ +               
Sbjct: 207 TAAIATLRGPLHGGANEAAMDLIMLYKTPSEAIAGIKRKLANKEL--------------- 251

Query: 353 GHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPW 412
              I GFGHAV R  DPR    + +A K  P+     L   + + +   ++++ K+   +
Sbjct: 252 ---IMGFGHAVYRERDPRNAIIKSWAQKLAPNAADGYLFD-ISDAIENTMQDEKKL---F 304

Query: 413 PNVDQHSGILLRYYGLVESNFYTVLFGVSRALG 445
           PN+D +S     +   + +  +T +F +SR  G
Sbjct: 305 PNLDFYSATAYHFLN-IPTKLFTPIFVMSRVTG 336


gb|AAB02962.1| citrate synthase
(411 aa)

Score: 88 bits (219), Expect: 3.37729e-16
Length: 357, Idn/Pos/Gap = 91/164/55 (25%/45%/15%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +L++ GE+P+  Q    C   K+ A            L +ER+H + Q     +      
Sbjct:  87 YLMIYGELPSSDQY---CNFTKKVAH---------HSLVNERLHYLFQ-----TFCSSSH 129

Query: 191 KMAEAYAQGAPKSTFWEYCLE--------DALTLIARLPAVAARIYRNTFHGGKHVPAEK 242
            MA   A     S F+   L          A+ +IA++P +AA  Y+ +       P   
Sbjct: 130 PMAIMLAAVGSLSAFYPDLLNFNETDYELTAIRMIAKIPTIAAMSYKYSIGQPFIYPDNS 189

Query: 243 IEKVDD-MGMRLARS-LGFELNEF--DELMRLYLVLHADHEGGNVSAHAVRLVGSALSDP 298
           ++  ++ + M  A     +++N    + L +++ +LHADHE  N S   VR+ GS+ ++P
Sbjct: 190 LDFTENFLHMMFATPCTKYKVNPIIKNALNKIF-ILHADHEQ-NASTSTVRIAGSSGANP 247

Query: 299 YLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHV--I 356
           +   + G+  L GP HG AN+ V    + M +++G    ++EN+ +   +   +     +
Sbjct: 248 FACISTGIASLWGPAHGGANEAV----INMLKEIG----SSENIPKYVAKAKDKNDPFRL 299

Query: 357 PGFGHAVLRRTDPRYTAQREFA------LKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKN 410
            GFGH V +  DPR    +E        L  L ++ + Q+  +L  +  +  +E    + 
Sbjct: 300 MGFGHRVYKSYDPRAAVLKETCKEVLNELGQLDNNPLLQIAIELEALALK--DEYFIERK 357

Query: 411 PWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPK 464
            +PNVD +SGI+ +  G + S  +TVLF ++R +G ++   W      P   I RP+
Sbjct: 358 LYPNVDFYSGIIYKAMG-IPSQMFTVLFAIARTVGWMAQ--WKEMHEDPEQKISRPR 411


gb|AAM49620.1| citrate synthase [Rickettsia sp. DT1]
(411 aa)

Score: 88 bits (218), Expect: 3.4629e-16
Length: 433, Idn/Pos/Gap = 102/189/68 (23%/43%/15%)

Query:  60 VRERFGEEVLDACTVNQAYG------GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQR 112
           ++   GE+V+D   V+          G  S  +     + +D  +GI R RG+ I     
Sbjct:  19 LKASIGEDVIDISRVSAEADCFTYDPGFMSTASCQSTVTYIDGDKGILRHRGYDI-----  73

Query: 113 LLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHER 172
                K   E+     + +LL+ GE+P+  Q  +  + +   + V            ++R
Sbjct:  74 -----KDLAEKSDFLEVAYLLIYGELPSGEQYNNFTKQVAHHSLV------------NDR 116

Query: 173 MHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLE--------DALTLIARLPAVA 224
           +H + Q     +       MA   A     S F+   L          A+ +IA++P +A
Sbjct: 117 LHYLFQ-----TFCSSSHPMAIMLAAVGSLSAFYPDLLNFKEADYELTAIRMIAKIPTIA 171

Query: 225 ARIYRNTFHGGKHVPAEKIEKVDD-MGMRLARSL-GFELNEF--DELMRLYLVLHADHEG 280
           A  Y+ +       P   ++  ++ + M  A     + +N    + L +++ +LHADHE 
Sbjct: 172 AMSYKYSIGQPFIYPDNSLDFTENFLHMMFATPYTKYTVNPIIKNALNKIF-ILHADHEQ 230

Query: 281 GNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTE 340
            N S   VR+ GS+ ++P+   + G+  L GP HG AN+ V    + M +++G+     +
Sbjct: 231 -NASTSTVRIAGSSGANPFACISTGIASLWGPAHGGANEAV----INMLKEIGSSEYIPK 285

Query: 341 NLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFA------LKHLPHDEMFQLVSKL 394
            + +   +   +   + GFGH V +  DPR    +E        L  L ++ + Q+  +L
Sbjct: 286 YIAKA--KDKNDPFRLMGFGHRVYKNYDPRAAVLKETCKEVLKELGQLDNNPLLQIAIEL 343

Query: 395 YEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDR 454
             +  +  +E    +  +PNVD +SGI+ +  G + S  +TVLF ++R +G ++   W  
Sbjct: 344 EAIALK--DEYFIERKLYPNVDFYSGIIYKAMG-IPSLMFTVLFAIARTVGWMAQ--WKE 398

Query: 455 ALGLP---IERPK 464
               P   I RP+
Sbjct: 399 MHEDPEQKISRPR 411


ref|NP_249486.1| citrate synthase 2 [Pseudomonas aeruginosa PAO1]
gb|AAG04184.1| citrate synthase 2 [Pseudomonas aeruginosa PAO1]
ref|ZP_00138394.2| COG0372: Citrate synthase [Pseudomonas aeruginosa UCBPP-PA14]
pir||B83547 citrate synthase 2 PA0795 [imported] - Pseudomonas aeruginosa (strain PAO1)
(375 aa)

Score: 88 bits (218), Expect: 3.61042e-16
Length: 330, Idn/Pos/Gap = 87/154/29 (26%/46%/8%)

Query: 127 EGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLL 186
           E + +LLL GE+P + Q+++  + L+ +  +P  +  +L+ +P +  HPM       S+L
Sbjct:  49 EEVAYLLLYGELPNKQQLDAYLKKLQGQRDLPQALKEVLERIPKD-AHPMDVMRTGASVL 107

Query: 187 QHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKV 246
                         P+ +F +   + A  L+A  PA+    YR T H G+ +     E  
Sbjct: 108 ----------GTLEPELSF-DQQRDVADRLLAAFPAIMTYWYRFT-HEGQRIDCNSDEPT 155

Query: 247 DDMGMRLARSLGFELNEFD-ELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAG 305
              G  LA   G + +E   ++M + L+L+A+HE  N S    R+  S LSD Y      
Sbjct: 156 IG-GHFLALLHGKKPSELHVKVMNVSLILYAEHEF-NASTFTARVCASTLSDLYSCVTGA 213

Query: 306 LNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLR 365
           +  L GPLHG AN+      +++ E+  +    T  L ++    L     I GFGHA+ +
Sbjct: 214 IGSLRGPLHGGANEAA----MELIERFSSPQEATAELLKM----LERKDKIMGFGHAIYK 265

Query: 366 RTDPRYTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRY 425
            +DPR    + ++ K L  +   +++  + E + + + EQ K+   +PN D +      +
Sbjct: 266 DSDPRNEVIKGWS-KQLADEVGDKVLFAVSEAIDKTMWEQKKL---FPNADFYHASAYHF 321

Query: 426 YGLVESNFYTVLFGVSRALGTLSSLVWDRA 455
            G + +  +T +F  SR  G  + +   RA
Sbjct: 322 MG-IPTKLFTPIFVCSRTSGWTAHVFEQRA 350


gb|AAV95425.1| citrate synthase I [Silicibacter pomeroyi DSS-3]
ref|YP_167384.1| citrate synthase I [Silicibacter pomeroyi DSS-3]
(431 aa)

Score: 88 bits (218), Expect: 3.82757e-16
Length: 356, Idn/Pos/Gap = 97/156/49 (27%/43%/13%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPM-TQFSV--AVSLLQ 187
           +LLL GE+PT + +E     + R   +  ++         +  HPM T   V  A+S   
Sbjct:  90 YLLLYGELPTAAALEKFETTITRHTMIHEQMHYFFRGFRRD-AHPMATMVGVVGAMSAFY 148

Query: 188 HESK-MAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKV 246
           H+S  +A+ + +                 LIA++P +AA  Y+ +       P   ++  
Sbjct: 149 HDSTDIADPHQREIASHR-----------LIAKMPTIAAMAYKYSIGQPFMYPRNDLDYA 197

Query: 247 DDMGMRLARSLGFELNEFDEL----MRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSF 302
            +  +++  ++  E    D +    M     LHADHE  N S   VRL  S+ ++P+   
Sbjct: 198 ANF-LQMCFAVPAEHYHVDPILARAMDRIFTLHADHEQ-NASTSTVRLASSSGANPFACI 255

Query: 303 AAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHA 362
           AAG+  L GP HG ANQ      L+M +++G+     E +     +   +   + GFGH 
Sbjct: 256 AAGIACLWGPAHGGANQAC----LEMLKEIGSPDRIPEFIARA--KDKNDPFRLMGFGHR 309

Query: 363 VLRRTDPRYTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKV---------KNPWP 413
           V +  DPR T  ++ A      DE+  L+      +    +E  +          K  +P
Sbjct: 310 VYKNFDPRATVMKQSA------DEVLDLLGVENNPILATAKELERAALADDYFAEKKLFP 363

Query: 414 NVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPKSV 466
           NVD +SGI+L   G   S F T +F VSR +G +S   W   L  P   I RP+ +
Sbjct: 364 NVDFYSGIILEAMGFPTSMF-TPIFAVSRTVGWVSQ--WKEQLADPQHKIGRPRQL 416


ref|ZP_00122907.1| COG0372: Citrate synthase [Haemophilus somnus 129PT]
(427 aa)

Score: 88 bits (217), Expect: 4.4851e-16
Length: 411, Idn/Pos/Gap = 100/180/47 (24%/43%/11%)

Query:  80 GMRSLKAMVYETSLLDPQEGIRF-RGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEI 138
           G  S  + V E + +D   GI   RG+ I +       AK +    +      LLL GE 
Sbjct:  46 GFMSTASCVSEITYIDGDNGILLHRGYPIADL------AKNADYLEVAH----LLLFGER  95

Query: 139 PTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQ 198
           P + +  +  + +K    V  ++ R       +  HPM       +++   S    A+  
Sbjct:  96 PNKEEYANFIKLVKNHTLVHEQISRFFHGFRRDS-HPM-------AIMCGVSGALAAFYH 147

Query: 199 GAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDD-MGMRLARSL 257
            +      E+    A+ L+A++P +AA  Y+ +       P  K+    + + M  A   
Sbjct: 148 DSLDINDIEHRELTAIRLLAKMPTLAAMCYKYSIGQPFMFPLNKLSYAGNFLYMMFATPC 207

Query: 258 G-FELNE-FDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHG 315
             +E+N   ++ M    +LHADHE  N S   VR   S+ ++P+   AAG+  L GP HG
Sbjct: 208 EPYEVNPVLEKAMDRIFILHADHEQ-NASTSTVRTAASSGANPFACIAAGIASLWGPAHG 266

Query: 316 LANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQR 375
            AN+      + M E++G+     E +     +   +   + GFGH V +  DPR    R
Sbjct: 267 GANEAC----INMLEEIGSVDRIPEYIARA--KDKNDPFRLMGFGHRVYKNYDPRAKVMR 320

Query: 376 EFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNP-------WPNVDQHSGILLRYYGL 428
           +   + L       + + L++V   +  E+  + +P       +PNVD +SGI+L+  G 
Sbjct: 321 QTCHEVLKE---LNIQTPLFDVAMEL--ERIALNDPYFIDHKLYPNVDFYSGIILKAIG- 374

Query: 429 VESNFYTVLFGVSRALGTLSSLVWDRAL---GLPIERPKSVTTQWIREHFE 476
           + ++ +TV+F ++R +G ++   W        + I RP+ +       +F+
Sbjct: 375 IPTSMFTVIFALARTVGWIAH--WKEMFKPGNMKIVRPRQLYKGHTERNFD 423


emb|CAE22195.1| Citrate synthase [Prochlorococcus marinus str. MIT 9313]
ref|NP_895846.1| Citrate synthase [Prochlorococcus marinus str. MIT 9313]
(404 aa)

Score: 88 bits (217), Expect: 5.12567e-16
Length: 369, Idn/Pos/Gap = 104/157/44 (28%/42%/11%)

Query: 112 RLLPRAKPSGEQPLPEGLL---WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDEL 168
           RL  R  P  E       L   +LL+ G++P+  Q+     +++    V   V  ++   
Sbjct:  49 RLAYRGYPIAELSAHSSFLETTYLLIWGDLPSPQQLRDFEAEVQMHRRVSFRVRDMMKCF 108

Query: 169 PHERMHPMTQF-SVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARI 227
           P    HPM    S A SL    S+ A       PK     Y     + LIA++P + A  
Sbjct: 109 PASG-HPMDALQSSAASLGLFYSRRA----IDDPK-----YVYNAVVRLIAKIPTMVAAF 158

Query: 228 YRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDEL----MRLYLVLHADHEGGNV 283
                  G+    + I+  DD+             E D L    +   L+LHA+H   N 
Sbjct: 159 --KLIRKGQ----DPIQPRDDLAYSANFLYMLTEREPDPLAARVLDRCLILHAEHSL-NA 211

Query: 284 SAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLR 343
           S  + R+  S L+DPY   A+ +  LAGPLHG AN++V    L M E++G    + E+  
Sbjct: 212 STFSARVTASTLTDPYAVVASAVGTLAGPLHGGANEDV----LAMLEEIG----SPEHAG 263

Query: 344 ELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFA---LKHLPHDEMFQLVSKLYEVVPR 400
           +   E +     + GFGH   R  DPR    +  A         DEM+ +   L +    
Sbjct: 264 DYLDEAIASKRKVMGFGHREYRVKDPRAVILQGLAEELFARFGTDEMYDVAKALEQAAAT 323

Query: 401 VLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP- 459
            L  +G     +PNVD +SG++ R  G +  + +T +F +SR  G L+   W   LG   
Sbjct: 324 RLGPKGI----YPNVDFYSGLVYRKLG-IPRDLFTPVFAISRVAGWLAH--WREQLGANR 376

Query: 460 IERPKSVTT 468
           I RP  + T
Sbjct: 377 IFRPSQIYT 385


ref|YP_032322.1| Citrate synthase [Bartonella quintana str. Toulouse]
emb|CAF26174.1| Citrate synthase [Bartonella quintana str. Toulouse]
sp|P51034|CISY_BARQU Citrate synthase
(438 aa)

Score: 87 bits (216), Expect: 6.05653e-16
Length: 355, Idn/Pos/Gap = 94/158/39 (26%/44%/10%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSV---AVSLLQ 187
           +LLL GE+PT+ +     + + +   V  +  R       +  HPM        A+S   
Sbjct:  88 YLLLYGELPTKQEKIDFDRCIMQHMMVHEQFTRFFHGFRRDS-HPMAVMVACLGAMSAFY 146

Query: 188 HESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVD 247
           H+S   +   Q           +  A+ LI+++P +AA  Y+ +       P   +    
Sbjct: 147 HDSIDIKDAQQR----------MIAAIRLISKVPTLAAMAYKYSIGQAFVYPRNDLSYAA 196

Query: 248 DMGMRLARSLGFELNEFDEL----MRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFA 303
           +  + +  S+  E  + + +    M     LHADHE  N S   VRLVGS+ ++P+   A
Sbjct: 197 NF-LHMCFSVPCEEYKINPVLSRAMDRIFTLHADHEQ-NASTSTVRLVGSSGANPFACIA 254

Query: 304 AGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAV 363
           AG+  L GP HG AN+  L+    M +K+G+     E +     +   +   + GFGH V
Sbjct: 255 AGVACLWGPAHGGANEACLK----MLQKIGSVERIPEFIARA--KDKNDPFRLMGFGHRV 308

Query: 364 LRRTDPRYTAQREF---ALKHL--PHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQH 418
            +  DPR    ++     LK L    D +  +   L      + +E    K  +PNVD +
Sbjct: 309 YKNYDPRAKIMQQTCHEVLKELNIQDDPLLDIAIALENTA--LNDEYFIEKKLYPNVDFY 366

Query: 419 SGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPKSVTTQW 470
           SGI L+  G   +  +TVLF ++R++G ++   W   +  P   I RP+ + T +
Sbjct: 367 SGITLKALGF-PTEMFTVLFALARSIGWVAQ--WKEMIEDPAQKIGRPRQLYTGY 418


emb|CAA05174.1| citrate synthase [Haloferax volcanii]
pir||T44615 citrate (si)-synthase (EC 4.1.3.7) [imported] - Haloferax volcanii (fragment)
(379 aa)

Score: 87 bits (216), Expect: 6.31454e-16
Length: 331, Idn/Pos/Gap = 98/145/32 (29%/43%/9%)

Query: 127 EGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLL 186
           E +L+LL  G +PT  ++++   +L     +   VL +  EL  +   PM      VS +
Sbjct:  46 EEVLYLLWHGALPTGEELDAFSDELAAHRDLDDGVLDVARELAEQDESPMAALRTLVSAM 105

Query: 187 QHESKMAEAYAQGA--PKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIE 244
                   AY + A     T  E  LE A  + A++P+V A  Y     G  +V  E  E
Sbjct: 106 S-------AYDESADFEDVTDREVNLEKAKRITAKMPSVLA-AYARFRRGDDYV--EPDE 155

Query: 245 KVDDMGMRLARSLGFELNE-FDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFA 303
            ++     L    G E NE   E   + LVLHADH G N S  +  +  S LSD Y +  
Sbjct: 156 SLNHAANFLYMLNGEEPNEVLAETFDMALVLHADH-GLNASTFSAMVTSSTLSDLYSAVT 214

Query: 304 AGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAV 363
           + +  L+G LHG AN  V+R L  + +       +  +  E   + L  G  + GF H V
Sbjct: 215 SAIGTLSGSLHGGANANVMRMLKDVDD-------SDMDPTEWVKDALDRGERVAGFVHRV 267

Query: 364 LRRTDPRYT--AQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGI 421
               DPR      +  AL     D       K YE+   + E  G+ K   PNVD +S  
Sbjct: 268 YNVKDPRAKILGAKSEALGEAAGD------MKWYEMSVAIEEYIGEEKGLAPNVDFYSAS 321

Query: 422 LLRYYGL-VESNFYTVLFGVSRALGTLSSLV 451
              YY + +  + YT +F VSRA G ++ ++
Sbjct: 322 --TYYQMGIPIDLYTPIFAVSRAGGWIAHVL 350


ref|ZP_00124190.2| COG0372: Citrate synthase [Pseudomonas syringae pv. syringae B728a]
(379 aa)

Score: 87 bits (216), Expect: 6.58355e-16
Length: 333, Idn/Pos/Gap = 87/149/35 (26%/44%/10%)

Query: 127 EGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLL 186
           E + +LLL GE+P ++++ +    LKR   +P  +  +L+ +P +  HPM       S+L
Sbjct:  53 EEVAYLLLYGELPNQAELSAYMDKLKRLRDLPQALKEVLERIPAD-THPMDVMRTGASML 111

Query: 187 QHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKV 246
                         P+ +F +   +    L+A  PA+    YR + H G+ +     E  
Sbjct: 112 ----------GTLEPERSF-DQQRDSTGRLLAAFPAIMCYWYRFS-HDGRRIDCTSAE-- 157

Query: 247 DDMGMRLARSL----GFELNEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSF 302
           D +G      L      EL+   ++M + L+L+A+HE  N S    R+  S LSD Y   
Sbjct: 158 DSIGGHFLHLLLDKAPSELHR--KVMDVSLILYAEHEF-NASTFTARVCASTLSDLYSCV 214

Query: 303 AAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHA 362
            A +  L GPLHG AN+  +  +         R  + E   +     L     I GFGHA
Sbjct: 215 TAAIGTLRGPLHGGANEAAMEMI--------QRFASAEEATKGTLGMLERKEKIMGFGHA 266

Query: 363 VLRRTDPRYTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGIL 422
           + + +DPR    + ++ K L  +    ++  + E + +V+ EQ K+   +PN D +    
Sbjct: 267 IYKESDPRNEVIKGWS-KKLADEVGDTVLFPVSEAIDKVMWEQKKL---FPNADFYHASA 322

Query: 423 LRYYGLVESNFYTVLFGVSRALGTLSSLVWDRA 455
             + G + +  +T +F  SR  G  + +   RA
Sbjct: 323 YHFMG-IPTKLFTPIFVCSRLTGWAAHVFEQRA 354


gb|AAC02810.1| citrate synthase [Rickettsia sp.]
(356 aa)

Score: 87 bits (216), Expect: 6.75042e-16
Length: 381, Idn/Pos/Gap = 95/168/42 (24%/44%/11%)

Query:  80 GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEI 138
           G  S  +     + +D  +GI R RG+ I          K   E+     + +LL+ GE+
Sbjct:   1 GFMSTASCRSTITYIDGDQGILRHRGYDI----------KDLAEKSDFLEVAYLLIYGEL  50

Query: 139 PTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAV-SLLQHESKMAEAYA 197
           P   Q     + +   A V  E L  L +      HPM     AV SL      +   + 
Sbjct:  51 PNSKQYNDFTKKVAHHALVN-ERLHYLFQTFCSSSHPMAIMLAAVGSLSAFYPDLLNFFK 109

Query: 198 QGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDD-MGMRLARS 256
           +   + T        A+ +IA++P +AA  Y+ +       P   ++  ++ + M  A  
Sbjct: 110 EADYELT--------AIRMIAKIPTIAAMSYKYSIGQPFVYPDNSLDFTENFLHMMFATP 161

Query: 257 L-GFELNEF--DELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPL 313
              +++N    + L +++ +LHADHE  N S   VR+ GS+ ++P+   + G+  L GP 
Sbjct: 162 CEKYKVNPVVKNALNKIF-ILHADHEQ-NASTSTVRIAGSSGANPFACVSTGIASLWGPA 219

Query: 314 HGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTA 373
           HG AN+ V+  L  +   + N P      ++       +   + GFGH V +  DPR   
Sbjct: 220 HGGANEAVINMLKDIGS-VENIPKYIAKAKD-----KNDNFRLMGFGHRVYKNYDPRAAV 273

Query: 374 QREFA------LKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYG 427
            +E        L  L ++ + Q+  +L  +  +  +E    +  +PNVD +SGI+ +  G
Sbjct: 274 LKETCKEVLKELGQLDNNPLLQIAIELEAIALK--DEYFIERKLYPNVDFYSGIIYKAMG 331

Query: 428 LVESNFYTVLFGVSRALGTLS 448
            +    +TVLF  +R +G ++
Sbjct: 332 -IPPQMFTVLFATARTVGWMA 351


gb|AAP31416.1| citrate synthase [Anaplasma platys]
(411 aa)

Score: 87 bits (216), Expect: 6.86402e-16
Length: 397, Idn/Pos/Gap = 106/168/44 (26%/42%/11%)

Query:  80 GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEI 138
           G  S  A   E + +D ++GI R RG  I         A   G +     +  LLL G +
Sbjct:  45 GFMSTAACSSEITFIDGEKGILRHRGLDI---------ADLIGIKGGFCSVAHLLLYGVL  95

Query: 139 PTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQ 198
           P+++  E     +  + A+  +VL ++     +  HPM       S L        A   
Sbjct:  96 PSDTVFEQFSAAIGAQHALSSDVLGVISSFRRD-AHPMAILMACFSTLA-------AKYH 147

Query: 199 GAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDD-MGMRLARSL 257
           G  +        E A+  IA++P++ A IYR+        P   +    + + M      
Sbjct: 148 GDNRGN-----EELAVLAIAQVPSLVAAIYRHRMGLELVSPDTSLSYTGNFVKMMFGALE 202

Query: 258 GFELNEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLA 317
               +  +E +    ++HADHE  N S   VR+ GSA ++ +   AAG   L GP HG A
Sbjct: 203 KTRADAIEEALDAIFIMHADHEQ-NASTATVRMAGSAGTELFACLAAGTATLWGPAHGGA 261

Query: 318 NQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREF 377
           N+ V+R    M E +G+ P   E       +   +  ++ GFGH V +  DPR     + 
Sbjct: 262 NEAVIR----MLESIGS-PDKVEEFIGFVKDNNSKVRLM-GFGHRVYKSYDPRAKILGQI 315

Query: 378 ALKHLPH----DEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNF 433
           +   L +    DE+  +  +L      + +E    +  +PNVD +SGI+LR  G V    
Sbjct: 316 SRSVLDNLGCSDELLGVAEELERCA--LQDEYFVERKLYPNVDFYSGIVLRAMG-VPVEM 372

Query: 434 YTVLFGVSRALGTLSSLVWDRAL----GLPIERPKSV 466
           YT  F ++R  G +S   W   L     L I RP+ +
Sbjct: 373 YTTFFALARTAGWVSQ--WCELLRGSESLKICRPRQL 407


ref|YP_018992.1| citrate synthase mmgd [Bacillus anthracis str. 'Ames Ancestor']
ref|NP_844731.1| citrate synthase MmgD [Bacillus anthracis str. Ames]
ref|YP_036452.1| citrate synthase [Bacillus thuringiensis serovar konkukian str. 97-27]
ref|YP_028449.1| citrate synthase MmgD [Bacillus anthracis str. Sterne]
ref|NP_656204.1| citrate_synt, Citrate synthase [Bacillus anthracis str. A2012]
gb|AAP26217.1| citrate synthase MmgD [Bacillus anthracis str. Ames]
gb|AAT62187.1| citrate synthase [Bacillus thuringiensis serovar konkukian str. 97-27]
gb|AAT31467.1| citrate synthase MmgD [Bacillus anthracis str. 'Ames Ancestor']
gb|AAT54500.1| citrate synthase MmgD [Bacillus anthracis str. Sterne]
(372 aa)

Score: 87 bits (216), Expect: 7.09697e-16
Length: 323, Idn/Pos/Gap = 89/147/30 (27%/45%/9%)

Query: 132 LLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESK 191
           LLL   +P E +  ++ + LK   AVP  V  +L  LP E  HPM      VS L     
Sbjct:  53 LLLEEHLPNEDEKATLEKKLKEEYAVPEGVFNVLKALPKE-THPMDGLRTGVSALAGYDN 111

Query: 192 MAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFH-GGKHVPAEKIEKVDDMG 250
             E  +    KS  ++        L++++P + A    N++H      P E ++++    
Sbjct: 112 DIENRSLEVNKSRGYK--------LLSKVPNIVA----NSYHILNNEEPIEPLKELSYSA 159

Query: 251 MRLARSLGFELNEFDE-LMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGL 309
                  G +  E +E +    LVL+++HE  N S    R++ S  SD Y +    +  L
Sbjct: 160 NFFYMLTGKKPTELEEKIFDRSLVLYSEHEMPN-STFTARVIASTQSDLYGALTGAVASL 218

Query: 310 AGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAV-LRRTD 368
            G LHG AN+ V+  LL+     GN     E   EL  + L     I GFGH V +++ D
Sbjct: 219 KGSLHGGANEAVMYMLLEA----GN----VEKFEELLQKKLYNKEKIMGFGHRVYMKKMD 270

Query: 369 PRYTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGL 428
           PR    +E ALK L   +    + ++ E   +++E++   K  +PN+D ++  +    G 
Sbjct: 271 PRALMMKE-ALKQLCDVKGDYTLYEMCEAGEKIMEKE---KGIYPNLDYYAAPVYWMLG- 325

Query: 429 VESNFYTVLFGVSRALGTLSSLV 451
           +    YT +F  SR +G  + ++
Sbjct: 326 IPIQLYTPIFFSSRTVGLCAHVI 348


ref|YP_052208.1| citrate synthase [Erwinia carotovora subsp. atroseptica SCRI1043]
emb|CAG77018.1| citrate synthase [Erwinia carotovora subsp. atroseptica SCRI1043]
(427 aa)

Score: 87 bits (216), Expect: 7.15643e-16
Length: 350, Idn/Pos/Gap = 87/161/34 (24%/46%/9%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           ++LL G+ P+         ++ R   V  ++ R+      +  HPM      V  L    
Sbjct:  88 YILLHGDAPSPEAYAKFADNITRHTLVHEQITRMFSGFRRDS-HPMALMCAVVGALA--- 143

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMG 250
               A+          E+    A+ L++++P +AA  Y+ +       P   +    +  
Sbjct: 144 ----AFYHDVLDINNAEHRELAAVRLLSKMPTLAAMCYKYSVEQPSVYPRNSLSYTGNF- 198

Query: 251 MRLARSL---GFELNE-FDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGL 306
           + +  S+    +E+N   +  M   L+LHADH G   S  AVR  GS+ ++P+   AAGL
Sbjct: 199 LHMLFSIPAEKYEVNPVLERAMNRILILHADH-GQCPSTMAVRASGSSGANPFACIAAGL 257

Query: 307 NGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRR 366
             + GPLHG AN+  +R L ++K  +   P      ++ C ++ R    + GFG++V + 
Sbjct: 258 ASMWGPLHGGANEACMRMLEEIK-TVDRVPEFVRRAKDRC-DSFR----LMGFGNSVYQH 311

Query: 367 TDPRYTAQREFALKHLP----HDEMFQLVSKLYEVVPRVLEEQGKVKNP-WPNVDQHSGI 421
            DPR    R+   + L      D + Q+  +L  +    + +   ++N  +P+VD ++ +
Sbjct: 312 FDPRAAILRKTCYEVLNELGMEDSLLQVAMELEHI---AMTDAYFLENKLYPSVDFYTSV 368

Query: 422 LLRYYGLVESNFYTVLFGVSRALGTLSSLVWD---RALGLPIERPKSVTT 468
           +L+  GL  S+ +TV+  V R +G ++   WD   +   + I RP+ + T
Sbjct: 369 ILKAMGL-PSSMFTVISTVGRTIGWIAH--WDEMHKQQEISIYRPRQIYT 415


ref|NP_148116.1| citrate synthase [Aeropyrum pernix K1]
dbj|BAA80714.1| 394aa long hypothetical citrate synthase [Aeropyrum pernix K1]
pir||E72553 probable citrate synthase APE1713 - Aeropyrum pernix (strain K1)
(394 aa)

Score: 87 bits (215), Expect: 7.91007e-16
Length: 361, Idn/Pos/Gap = 102/159/42 (28%/44%/11%)

Query:  92 SLLDPQ-EGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQD 150
           S +DP+ E   +RG++I +           GE         L+L G +P + +++ +   
Sbjct:  31 SGVDPKGEATIYRGYTIEDI----------GEHASFYEAAHLILFGRLPCDEELKEIKSK  80

Query: 151 LKRRAAVPPEVLRLLDELPHERM-HPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYC 209
           + +     PE  +L D + H  + HPM       +LL       + YA   P+  F E  
Sbjct:  81 IDKYRGQIPE--KLFDAMKHVPVTHPMYYGIYGTALL------GQYYA---PEWRFDEDF 129

Query: 210 LED-ALTLIARLPAVAARIYRNTFHGGKHVP-AEKIEKVDDMGMRLARSLG-FELNEFDE 266
           L D AL L A+LP +    +    HG    P   K    D + M + R     E   F+ 
Sbjct: 130 LYDHALRLTAQLPVIFTTGWNLAHHGTFLRPDPSKDHAWDVLRMIVMREPSDIEARAFES 189

Query: 267 LMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLL 326
                LVL+ DH G N S    R++GS LSD Y + A G+  L GPLHG AN++ +   L
Sbjct: 190 T----LVLYMDH-GFNASTFTTRVIGSTLSDLYSAVAGGIAALKGPLHGGANEKAMEMFL 244

Query: 327 QMKEKLGNRPMTT-ENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHD 385
              +K   + +   + + E   E L     I GFGH + +  DPR     +F  K    +
Sbjct: 245 DAMKKAEEKGVPLYDYIEEYIKEKLARKEKIMGFGHRIYKLHDPRTDVAAKFVAKLKDGE 304

Query: 386 EMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGL-VESNFYTVLFGVSRAL 444
              +++ K  EV+ R      + K P  N+D ++ +L  YY L +    YT +F + R +
Sbjct: 305 FWMKVLKKAEEVMWR------EKKIP-ANIDLYTAVL--YYQLGIPIPMYTPIFAMGRVV 355

Query: 445 G 445
           G
Sbjct: 356 G 356


ref|YP_171622.1| citrate synthase [Synechococcus elongatus PCC 6301]
dbj|BAD79102.1| citrate synthase [Synechococcus elongatus PCC 6301]
(393 aa)

Score: 87 bits (215), Expect: 8.11057e-16
Length: 415, Idn/Pos/Gap = 101/176/54 (24%/42%/13%)

Query:  65 GEEVLDACTVNQAYGGMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQ 123
           G+  +    V++   G+  + A +   S +D Q G+  +RG SI +            +Q
Sbjct:   2 GKPRIAMTAVSEFRPGLEGVPATLSSISFVDGQRGVLEYRGISIEQL----------AQQ  51

Query: 124 PLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAV 183
                  +LL+ G +PT+ ++     +++    +   +  ++   P +  HPM     + 
Sbjct:  52 SSFLETAYLLIWGHLPTQQELTEFEHEIRYHRRIKFRIRDMMKCFP-DSGHPMDALQASA 110

Query: 184 SLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKI 243
           + L         Y++ A      EY     + L+A++P + A         G   P +  
Sbjct: 111 AAL------GLFYSRRALDDP--EYIRAAVVRLLAKIPTMVAAF--QLIRKGND-PIQPR 159

Query: 244 EKVDDMGMRLARSLGFELNEFD------ELMRLYLVLHADHEGGNVSAHAVRLVGSALSD 297
           +++D      A +  + L E +       +  + L LHA+H   N S  +  +  S L+D
Sbjct: 160 DELD-----YAANFLYMLTEREPDPVAARIFDICLTLHAEHTI-NASTFSAMVTASTLTD 213

Query: 298 PYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIP 357
           PY   A+ +  LAGPLHG AN+EV    L M E +G    + EN+       +     I 
Sbjct: 214 PYAVVASAVGTLAGPLHGGANEEV----LDMLEAIG----SVENVEPYLDHCIATKTRIM 265

Query: 358 GFGHAVLRRTDPRYTAQREFA---LKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPN 414
           GFGH V +  DPR    +  A        HD  +++   + +     L  +G     +PN
Sbjct: 266 GFGHRVYKVKDPRAVILQNLAEQLFDIFGHDPYYEIAVAVEKAAAERLSHKGI----YPN 321

Query: 415 VDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP-IERPKSVTT 468
           VD +SG++ R  G + S+ +T +F ++R  G L+   W   L    I RP  + T
Sbjct: 322 VDFYSGLVYRKLG-IPSDLFTPVFAIARVAGWLAH--WKEQLNENRIFRPTQIYT 373


gb|AAR96315.1| citrate synthase [Rickettsia bellii]
(384 aa)

Score: 87 bits (215), Expect: 8.38583e-16
Length: 400, Idn/Pos/Gap = 99/175/47 (24%/43%/11%)

Query:  80 GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEI 138
           G  S  +     + +D  +GI R RG+ I          K   E+     + +LL+ GE+
Sbjct:  17 GFMSTASCRSTITYIDGDQGILRHRGYDI----------KDLAEKSDFLEVAYLLIYGEL  66

Query: 139 PTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAV-SLLQHESKMAEAYA 197
           P   Q     + +   A V  E L  L +      HPM     AV SL      +   + 
Sbjct:  67 PNNKQYNDFTKKVAHHALVN-ERLHYLFQTFCSSSHPMAIMLAAVGSLSAFYPDLLNFFK 125

Query: 198 QGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDD-MGMRLARS 256
           +   + T        A+ +IA++P +AA  Y+ +       P   ++  ++ + M  A  
Sbjct: 126 EADYELT--------AIRMIAKIPTIAAMSYKYSIGQPFVYPDNSLDFTENFLHMMFATP 177

Query: 257 L-GFELNEF--DELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPL 313
              +++N    + L +++ +LHADHE  N S   VR+ GS+ ++P+   + G+  L GP 
Sbjct: 178 CEKYKVNPVIKNALNKIF-ILHADHEQ-NASTSTVRIAGSSGANPFACVSTGIASLWGPA 235

Query: 314 HGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTA 373
           HG AN+ V+  L ++   + N P      ++       +   + GFGH V +  DPR   
Sbjct: 236 HGGANEAVINMLKEIGS-VENIPKYIAKAKD-----KNDNFRLMGFGHRVYKNYDPRAAV 289

Query: 374 QREFA------LKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYG 427
            +E        L  L ++ + Q+  +L  +  +  +E    +  +P+VD +SGI+ +  G
Sbjct: 290 LKETCKEVLKELGQLDNNPLLQIAIELEAIALK--DEYFIERKLYPDVDFYSGIIYKAMG 347

Query: 428 LVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPK 464
            +    +TVLF  +R +G ++   W      P   I RP+
Sbjct: 348 -IPPQMFTVLFATARTVGWMAQ--WKEMHEDPEQKISRPR 384


ref|NP_693089.1| citrate synthase II [Oceanobacillus iheyensis HTE831]
dbj|BAC14124.1| citrate synthase II [Oceanobacillus iheyensis HTE831]
(373 aa)

Score: 87 bits (215), Expect: 8.74307e-16
Length: 333, Idn/Pos/Gap = 88/144/40 (26%/43%/12%)

Query: 127 EGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLL 186
           E +++LL   ++P +S+++ +   L     +P  ++  L       +HPM     A+SLL
Sbjct:  43 EEIIYLLWNQKLPNKSELDELKSQLAENMDIPDAIINHLRSYDLNTVHPMAALRTAISLL 102

Query: 187 QHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKV 246
                 A+   + A K          A+ + A++  +     R     G+    E ++  
Sbjct: 103 GLYDNEADVMDEQANK--------RKAVRIQAQIATIVTTFSR--IRKGQ----EPVKPK 148

Query: 247 DDMGMRLARSLGFELNEFD------ELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYL 300
            D+    A +  + LN  +      E +   LVLHADHE  N S    R+  + LSD Y 
Sbjct: 149 KDLSY--AENFIYMLNGKEPEDIEVEAINKALVLHADHEL-NASTFTARVCVATLSDIYS 205

Query: 301 SFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFG 360
              A +  L GPLHG AN+ V++ L ++ E+        EN      E L     I G G
Sbjct: 206 GITAAIGALKGPLHGGANENVMKMLTEIGEE--------ENAIPYIKEKLANKDKIMGMG 257

Query: 361 HAVLRRTDPRYTAQREFALKHLPHDEMFQLV--SKLYEVVPRVLEEQGKVKNPWPNVDQH 418
           H V R  DPR    RE +       E+ +L    K Y +  ++ +   + K    NVD +
Sbjct: 258 HRVYRTGDPRAKFLREMS------KELTKLTGQEKWYNMSVKIEDYIKENKGLPANVDFY 311

Query: 419 SGILLRYYGLVESNFYTVLFGVSRALGTLSSLV 451
           S  +    GL + + +T LF VSR  G ++ ++
Sbjct: 312 SASVYHSLGL-DHDIFTPLFAVSRTSGWIAHIL 343


ref|ZP_00236744.1| 2-methylcitrate synthase [Bacillus cereus G9241]
gb|EAL15668.1| 2-methylcitrate synthase [Bacillus cereus G9241]
(372 aa)

Score: 87 bits (215), Expect: 8.8902e-16
Length: 323, Idn/Pos/Gap = 89/147/30 (27%/45%/9%)

Query: 132 LLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESK 191
           LLL   +P E +  ++ + LK   AVP  V  +L  LP E  HPM      VS L     
Sbjct:  53 LLLEEHLPNEDEKATLERKLKEEYAVPEGVFNVLKALPKE-THPMDGLRTGVSALAGYDN 111

Query: 192 MAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFH-GGKHVPAEKIEKVDDMG 250
             E  +    KS  ++        L++++P + A    N++H      P E ++++    
Sbjct: 112 DIENRSLEVNKSRGYK--------LLSKVPNIVA----NSYHILNNEEPIEPLKELSYSA 159

Query: 251 MRLARSLGFELNEFDE-LMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGL 309
                  G +  E +E +    LVL+++HE  N S    R++ S  SD Y +    +  L
Sbjct: 160 NFFYMLTGKKPTELEEKIFDRSLVLYSEHEMPN-STFTARVIASTQSDLYGALTGAVASL 218

Query: 310 AGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAV-LRRTD 368
            G LHG AN+ V+  LL+     GN     E   EL  + L     I GFGH V +++ D
Sbjct: 219 KGSLHGGANEAVMYMLLEA----GN----VEKFEELLQKKLYNKEKIMGFGHRVYMKKMD 270

Query: 369 PRYTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGL 428
           PR    +E ALK L   +    + ++ E   +++E++   K  +PN+D ++  +    G 
Sbjct: 271 PRALMMKE-ALKQLCDVKGDYTLYEMCEAGEKIMEKE---KGIYPNLDYYAAPVYWMLG- 325

Query: 429 VESNFYTVLFGVSRALGTLSSLV 451
           +    YT +F  SR +G  + ++
Sbjct: 326 IPIQLYTPIFFSSRTVGLCAHVI 348


ref|ZP_00163326.1| COG0372: Citrate synthase [Synechococcus elongatus PCC 7942]
(386 aa)

Score: 87 bits (215), Expect: 9.11554e-16
Length: 406, Idn/Pos/Gap = 100/173/54 (24%/42%/13%)

Query:  74 VNQAYGGMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWL 132
           V++   G+  + A +   S +D Q G+  +RG SI +            +Q       +L
Sbjct:   4 VSEFRPGLEGVPATLSSISFVDGQRGVLEYRGISIEQL----------AQQSSFLETAYL  53

Query: 133 LLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKM 192
           L+ G +PT+ ++     +++    +   +  ++   P +  HPM     + + L      
Sbjct:  54 LIWGHLPTQQELTEFEHEIRYHRRIKFRIRDMMKCFP-DSGHPMDALQASAAAL------ 106

Query: 193 AEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMR 252
              Y++ A      EY     + L+A++P + A         G   P +  +++D     
Sbjct: 107 GLFYSRRALDDP--EYIRAAVVRLLAKIPTMVAAF--QLIRKGND-PIQPRDELD----- 156

Query: 253 LARSLGFELNEFD------ELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGL 306
            A +  + L E +       +  + L LHA+H   N S  +  +  S L+DPY   A+ +
Sbjct: 157 YAANFLYMLTEREPDPVAARIFDICLTLHAEHTI-NASTFSAMVTASTLTDPYAVVASAV 215

Query: 307 NGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRR 366
             LAGPLHG AN+EV    L M E +G    + EN+       +     I GFGH V + 
Sbjct: 216 GTLAGPLHGGANEEV----LDMLEAIG----SVENVEPYLDHCIATKTRIMGFGHRVYKV 267

Query: 367 TDPRYTAQREFA---LKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILL 423
            DPR    +  A        HD  +++   + +     L  +G     +PNVD +SG++ 
Sbjct: 268 KDPRAVILQNLAEQLFDIFGHDPYYEIAVAVEKAAAERLSHKGI----YPNVDFYSGLVY 323

Query: 424 RYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP-IERPKSVTT 468
           R  G + S+ +T +F ++R  G L+   W   L    I RP  + T
Sbjct: 324 RKLG-IPSDLFTPVFAIARVAGWLAH--WKEQLNENRIFRPTQIYT 366


ref|NP_832048.1| 2-methylcitrate synthase [Bacillus cereus ATCC 14579]
gb|AAP09249.1| 2-methylcitrate synthase [Bacillus cereus ATCC 14579]
(373 aa)

Score: 87 bits (215), Expect: 9.6638e-16
Length: 327, Idn/Pos/Gap = 90/148/30 (27%/45%/9%)

Query: 132 LLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESK 191
           LLL   +P E +  ++ + LK   AVP  V  +L  LP E  HPM      VS L     
Sbjct:  54 LLLEEHLPNEDEKVTLEKKLKEEYAVPEGVFNVLKALPKE-THPMDGLRTGVSALAGYDN 112

Query: 192 MAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFH-GGKHVPAEKIEKVDDMG 250
             E  +    KS  ++        L++++P + A    N++H      P E ++++    
Sbjct: 113 DIENRSLEVNKSRGYK--------LLSKVPNIVA----NSYHILNNEEPIEPLKELSYSA 160

Query: 251 MRLARSLGFELNEFDE-LMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGL 309
                  G +  E +E +    LVL+++HE  N S    R++ S  SD Y +    +  L
Sbjct: 161 NFFYMLTGKKPTELEEKIFDRSLVLYSEHEMPN-STFTARVIASTQSDLYGALTGAVASL 219

Query: 310 AGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAV-LRRTD 368
            G LHG AN+ V+  LL+     GN     E   EL  + L     I GFGH V +++ D
Sbjct: 220 KGSLHGGANEAVMYMLLEA----GN----VEKFEELLQKKLYNKEKIMGFGHRVYMKKMD 271

Query: 369 PRYTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGL 428
           PR    +E ALK L   +    + ++ E   +++E++   K  +PN+D ++  +    G 
Sbjct: 272 PRALMMKE-ALKQLCDVKGDYTLYEMCEAGEKIMEKE---KGIYPNLDYYAAPVYWMLG- 326

Query: 429 VESNFYTVLFGVSRALGTLSSLVWDRA 455
           +    YT +F  SR +G  + ++   A
Sbjct: 327 IPIQLYTPIFFSSRTVGLCAHVIEQHA 353


emb|CAB96386.1| citrate synthase [male-killing Rickettsia from Adalia bipunctata]
(355 aa)

Score: 87 bits (214), Expect: 1.03309e-15
Length: 390, Idn/Pos/Gap = 96/176/61 (24%/45%/15%)

Query:  80 GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEI 138
           G  S  +     + +D  +GI R+RG+ I          K   E+     + +LL+ GE+
Sbjct:   1 GFMSTASCRSTITYIDGDKGILRYRGYDI----------KDLAEKSDFLEVAYLLIYGEL  50

Query: 139 PTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQ 198
           P+  Q      +  ++ AV          L +ER+H + Q     +       MA   A 
Sbjct:  51 PSSEQY----NNFTKKVAV--------HSLVNERLHYLFQ-----TFCSSSHPMAIMLAA  93

Query: 199 GAPKSTFWEYCLE--------DALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDD-M 249
               S F+   L          A+ +IA++P +AA  Y+ +       P   ++  ++ +
Sbjct:  94 VGSLSAFYPDLLNFKEADYELTAIRMIAKIPTIAAMSYKYSIGQPFIYPDNALDFTENFL 153

Query: 250 GMRLARSL-GFELNEF--DELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGL 306
            M  A     +++N    + L +++ +LHADHE  N S   VR+ GS+ ++P+   + G+
Sbjct: 154 HMMFATPCEKYKVNPIIKNALNKIF-ILHADHEQ-NASTSTVRIAGSSGANPFACVSTGI 211

Query: 307 NGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHV--IPGFGHAVL 364
             L GP HG AN+ V    + M +++G    ++EN+ +   +   +     + GFGH V 
Sbjct: 212 ASLWGPAHGGANEAV----INMLKEIG----SSENIPQYIAKAKDKNDPFRLMGFGHRVY 263

Query: 365 RRTDPRYTAQREFA------LKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQH 418
           +  D R    +E        L  L  + + Q+  +L  +  +  +E    +  +PNVD +
Sbjct: 264 KNYDLRAAVLKETCKDVLKELGQLDGNPLLQIAIELEAIALK--DEYFIERKLYPNVDFY 321

Query: 419 SGILLRYYGLVESNFYTVLFGVSRALGTLS 448
           SGI+ +  G + S  +TVLF ++R +G ++
Sbjct: 322 SGIIYKAMG-IPSQMFTVLFAIARTVGWMA 350


dbj|BAB87841.1| citrate synthase [Anaplasma platys]
gb|AAS22130.1| citrate synthase [Anaplasma platys]
(411 aa)

Score: 87 bits (214), Expect: 1.05047e-15
Length: 397, Idn/Pos/Gap = 106/168/44 (26%/42%/11%)

Query:  80 GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEI 138
           G  S  A   E + +D ++GI R RG  I         A   G +     +  LLL G +
Sbjct:  45 GFMSTAACSSEITFIDGEKGILRHRGLDI---------ADLIGIKGGFCSVAHLLLYGVL  95

Query: 139 PTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQ 198
           P+++  E     +  + A+  +VL ++     +  HPM       S L        A   
Sbjct:  96 PSDTVFEQFLAAIGAQHALSSDVLGVISSFRRD-AHPMAILMACFSTLA-------AKYH 147

Query: 199 GAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDD-MGMRLARSL 257
           G  +        E A+  IA++P++ A IYR+        P   +    + + M      
Sbjct: 148 GDNRGN-----EELAVLAIAQVPSLVAAIYRHRMGLELVSPDPSLSYTGNFVKMMFGALE 202

Query: 258 GFELNEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLA 317
               +  +E +    ++HADHE  N S   VR+ GSA ++ +   AAG   L GP HG A
Sbjct: 203 KTRADAIEEALDAIFIMHADHEQ-NASTATVRMAGSAGTELFACLAAGTATLWGPAHGGA 261

Query: 318 NQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREF 377
           N+ V+R    M E +G+ P   E       +   +  ++ GFGH V +  DPR     + 
Sbjct: 262 NEAVIR----MLESIGS-PDKVEEFIGFVKDNNSKVRLM-GFGHRVYKSYDPRAKILGQI 315

Query: 378 ALKHLPH----DEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNF 433
           +   L +    DE+  +  +L      + +E    +  +PNVD +SGI+LR  G V    
Sbjct: 316 SRSVLDNLGCSDELLGVAEELERCA--LQDEYFVERKLYPNVDFYSGIVLRAMG-VPVEM 372

Query: 434 YTVLFGVSRALGTLSSLVWDRAL----GLPIERPKSV 466
           YT  F ++R  G +S   W   L     L I RP+ +
Sbjct: 373 YTTFFALARTAGWVSQ--WCELLRGSESLKICRPRQL 407


gb|AAU25534.1| citrate synthase III [Bacillus licheniformis ATCC 14580]
ref|YP_093600.1| MmgD [Bacillus licheniformis ATCC 14580]
ref|YP_081172.1| citrate synthase III [Bacillus licheniformis ATCC 14580]
gb|AAU42907.1| MmgD [Bacillus licheniformis DSM 13]
(371 aa)

Score: 87 bits (214), Expect: 1.19053e-15
Length: 390, Idn/Pos/Gap = 103/172/44 (26%/44%/11%)

Query:  80 GMRSLKAMVYETSLLDPQ-EGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEI 138
           G+  + A     S LD + E I  +G+ + E            EQ     L++LLL  ++
Sbjct:  10 GLEGVIAGETNISFLDTEAEQIVIKGYDLIEL----------AEQKTYLDLVYLLLQDKL  59

Query: 139 PTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQ 198
           P   +++ +   LK    +P  +  +L  LP+   HPM      +S L          +Q
Sbjct:  60 PDPMELKGIESALKSAYELPGGIYTILKSLPNN-THPMDALRTGISALAGYDPELNDRSQ 118

Query: 199 GAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARS-- 256
            A +S         AL LIA++P + A  YR         P +++    +    L     
Sbjct: 119 AANRSK--------ALRLIAQVPNITANSYRILHQKNVITPDKQLSFSQNFLYMLTEKEP 170

Query: 257 LGFELNEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGL 316
              E   FD+ + LY    ++HE  N S  A R++ S  +D Y +F      L G LHG 
Sbjct: 171 TPQETAVFDQTLMLY----SEHEMPN-STFAARVIASTNTDIYGAFTGAAASLKGHLHGG 225

Query: 317 ANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAV-LRRTDPRYTAQR 375
           AN+ V+  LL+ + K G          +L    L     I GFGH V +R+ DPR    +
Sbjct: 226 ANEAVMYMLLEGETKSG--------FCKLIEHKLSRKEKIMGFGHRVYMRKMDPRAALLK 277

Query: 376 EFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGL-VESNFY 434
           + AL  L H    Q + ++ +   +++ E+   K  +PN+D ++  +  YY L +  + Y
Sbjct: 278 K-ALYSLSHKTGRQDLYEMCDAGEKLMREE---KGLYPNLDYYAAPV--YYLLGIPIDLY 331

Query: 435 TVLFGVSRALGTLSSLVWDRALGLPIERPK 464
           T +F  +R++G LS+ V ++     + RP+
Sbjct: 332 TPIFFAARSVG-LSAHVIEQHEDNRLFRPR 360


emb|CAB96387.1| citrate synthase [male-killing Rickettsia from Adalia decempunctata]
(355 aa)

Score: 87 bits (214), Expect: 1.21056e-15
Length: 390, Idn/Pos/Gap = 96/176/61 (24%/45%/15%)

Query:  80 GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEI 138
           G  S  +     + +D  +GI R+RG+ I          K   E+     + +LL+ GE+
Sbjct:   1 GFMSTASCRSTITYIDGDKGILRYRGYDI----------KDLAEKSDFLEVAYLLIYGEL  50

Query: 139 PTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQ 198
           P+  Q      +  ++ AV          L +ER+H + Q     +       MA   A 
Sbjct:  51 PSSEQY----NNFTKKVAV--------HSLVNERLHYLFQ-----TFCSSSHPMAIMLAA  93

Query: 199 GAPKSTFWEYCLE--------DALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDD-M 249
               S F+   L          A+ +IA++P +AA  Y+ +       P   ++  ++ +
Sbjct:  94 VGSLSAFYPDLLNFKEADYELTAIRMIAKIPTIAAMSYKYSIGQPFIYPDNSLDFTENFL 153

Query: 250 GMRLARSL-GFELNEF--DELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGL 306
            M  A     +++N    + L +++ +LHADHE  N S   VR+ GS+ ++P+   + G+
Sbjct: 154 HMMFATPCEKYKVNPIIKNALNKIF-ILHADHEQ-NASTSTVRIAGSSGANPFACVSTGI 211

Query: 307 NGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHV--IPGFGHAVL 364
             L GP HG AN+ V    + M +++G    ++EN+ +   +   +     + GFGH V 
Sbjct: 212 ASLWGPAHGGANEAV----INMLKEIG----SSENIPKYIAKAKDKNDPFRLMGFGHRVY 263

Query: 365 RRTDPRYTAQREFA------LKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQH 418
           +  D R    +E        L  L  + + Q+  +L  +  +  +E    +  +PNVD +
Sbjct: 264 KNYDLRAAVLKETCKEVLKELGQLDGNPLLQIAIELEAIALK--DEYFIERKLYPNVDFY 321

Query: 419 SGILLRYYGLVESNFYTVLFGVSRALGTLS 448
           SGI+ +  G + S  +TVLF ++R +G ++
Sbjct: 322 SGIIYKAMG-IPSQMFTVLFAIARTVGWMA 350


gb|AAS49632.1| citrate synthase [Rickettsia sp. R300]
(383 aa)

Score: 87 bits (214), Expect: 1.26213e-15
Length: 407, Idn/Pos/Gap = 96/180/62 (23%/44%/15%)

Query:  80 GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEI 138
           G  S  +     + +D  +GI R RG+ I          K   E+     + +LL+ GE+
Sbjct:  17 GFMSTASCQSTITYIDGDKGILRHRGYDI----------KDLAEKSDFLEVAYLLIYGEL  66

Query: 139 PTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQ 198
           P+  Q  +  + +   + V            +ER+H + Q     +       MA   A 
Sbjct:  67 PSGEQYNNFTKQVAHHSLV------------NERLHYLFQ-----TFCSSSHPMAIMLAA 109

Query: 199 GAPKSTFWEYCLE--------DALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDD-M 249
               S F+   L          A+ +IA++P +AA  Y+ +       P   ++  ++ +
Sbjct: 110 VGSLSAFYPDLLNFKEADYELTAIRMIAKIPTIAAMSYKYSIGQPFIYPDNSLDFTENFL 169

Query: 250 GMRLARS-LGFELNEF--DELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGL 306
            M  A     +++N    + L +++ +LHADHE  N S   VR+ GS+ ++P+   + G+
Sbjct: 170 HMMFATPCTKYKVNPIIKNALNKIF-ILHADHEQ-NASTSTVRIAGSSGANPFACISTGI 227

Query: 307 NGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRR 366
             L GP HG AN+ V    + M +++G+     + + +   +   +   + GFGH + + 
Sbjct: 228 ASLWGPAHGGANEVV----INMLKEIGSSEYIPKYIAKA--KDKNDPFRLMGFGHRIYKN 281

Query: 367 TDPRYTAQREFA------LKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSG 420
            DPR    +E        L  L ++ + ++  +L  +  +  +E    +  +PNVD +SG
Sbjct: 282 YDPRAAVLKETCKEVLKELGQLDNNPLLRIAIELEAIALK--DEYFIERKLYPNVDFYSG 339

Query: 421 ILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPK 464
           I+ +  G + S  +TVLF ++R +G ++   W      P   I RP+
Sbjct: 340 IIYKAMG-IPSQMFTVLFAIARTVGWMAQ--WKEMHEDPEQKISRPR 383


ref|NP_969318.1| hypothetical protein Bd2511 [Bdellovibrio bacteriovorus HD100]
emb|CAE80311.1| cit [Bdellovibrio bacteriovorus HD100]
(388 aa)

Score: 87 bits (214), Expect: 1.27271e-15
Length: 345, Idn/Pos/Gap = 84/151/36 (24%/43%/10%)

Query: 108 PECQRLLPRAKPS---GEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRL 164
           P    L+ R  P     E    E + +L+  GE+P   Q+    +  +    +   +L +
Sbjct:  37 PHTNSLIYRGYPVQDLAENCSFEEVAFLMYNGELPNAGQLAEFSKKERSYREISTTLLNV  96

Query: 165 LDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYC----LEDALTLIARL 220
           +  LP ++ HPM     AVS L            GA  +  W+      ++ A+ L+A++
Sbjct:  97 IKALP-QKCHPMDSIRTAVSFL------------GAEDARIWDASPATNMDKAMMLLAKI 143

Query: 221 PAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVLHADHEG 280
           P + A  YR    G   +P +    + +    +         E  +   + L+L+A+H  
Sbjct: 144 PTMVAADYRFK-KGLDFIPPKADLSIAENFFHMCFG-KVPQKEVVKAFDVSLILYAEHSF 201

Query: 281 GNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTE 340
            N S    R+V S  SD Y +  AG+  L GPLHG AN+ V+  + ++ +     P   E
Sbjct: 202 -NASTFTARVVTSTQSDIYSATVAGIGALKGPLHGGANEMVMHMMKEIAD-----PAKAE 255

Query: 341 NLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSKLYEVVPR 400
              +   + L +   + GFGH V R  D R    +++A + +      Q   ++Y  + +
Sbjct: 256 ---QWMLDALAQKKKVMGFGHRVYRSGDSRVPTMKKYA-QVMADVTGEQKWMQMYTALEK 311

Query: 401 VLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALG 445
           V+ ++ K+   +PN+D  +G      G  E +F+T +F ++R  G
Sbjct: 312 VMVDKKKI---YPNLDFPAGPAYYMMGF-EIDFFTPIFVMARTTG 352


ref|NP_792107.1| 2-methylcitrate synthase [Pseudomonas syringae pv. tomato str. DC3000]
gb|AAO55802.1| 2-methylcitrate synthase [Pseudomonas syringae pv. tomato str. DC3000]
(375 aa)

Score: 86 bits (213), Expect: 1.39504e-15
Length: 359, Idn/Pos/Gap = 95/161/41 (26%/44%/11%)

Query:  99 GIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVP 158
           G+ +RG+ + E          + E    E + +LLL GE+PT+SQ+ +    LK    +P
Sbjct:  31 GLTYRGYDVREL---------AAEAQFEE-VAYLLLYGELPTQSQLAAYLGKLKGLRDLP  80

Query: 159 PEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALT-LI 217
             +  +L+ +P +  HPM       S+L              P+ +F +    DA   L+
Sbjct:  81 QALKEVLERIPAD-THPMDVMRTGASML----------GTLEPELSFDQQ--RDATDRLL 127

Query: 218 ARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFD-ELMRLYLVLHA 276
           A  PA+    YR + H G+ +     E     G  L   L    +E   ++M + L+L+A
Sbjct: 128 AAFPAIMCYWYRFS-HDGQRIDCTTDESSIG-GHFLHLLLDKTPSELHRKVMDVSLILYA 185

Query: 277 DHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRP 336
           +HE  N S    R+  S LSD Y    A +  L GPLHG AN+      ++M ++  +  
Sbjct: 186 EHEF-NASTFTARVCASTLSDLYSCVTAAIGTLRGPLHGGANEAA----MEMIQRFASAD 240

Query: 337 MTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSKLYE 396
             T+    +    L     I GFGHA+ + +DPR    + ++ K L  +    ++  + E
Sbjct: 241 EATQGTLGM----LERKEKIMGFGHAIYKESDPRNEVIKGWS-KKLADEAGDSVLFPVSE 295

Query: 397 VVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRA 455
            + +V+ EQ K+   +PN D +      + G + +  +T +F  SR  G  + +   RA
Sbjct: 296 AIDKVMWEQKKL---FPNADFYHASAYHFMG-IPTKLFTPIFVCSRLTGWAAHVFEQRA 350


emb|CAB96385.1| citrate synthase [male-killing Rickettsia from Adalia bipunctata]
(355 aa)

Score: 86 bits (213), Expect: 1.41852e-15
Length: 390, Idn/Pos/Gap = 96/176/61 (24%/45%/15%)

Query:  80 GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEI 138
           G  S  +     + +D  +GI R+RG+ I          K   E+     + +LL+ GE+
Sbjct:   1 GFMSTASCRSTITYIDGDKGILRYRGYDI----------KDLAEKSDFLEVAYLLIYGEL  50

Query: 139 PTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQ 198
           P+  Q      +  ++ AV          L +ER+H + Q     +       MA   A 
Sbjct:  51 PSSEQY----NNFTKKVAV--------HSLVNERLHYLFQ-----TFCSSSHPMAIMLAA  93

Query: 199 GAPKSTFWEYCLE--------DALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDD-M 249
               S F+   L          A+ +IA++P +AA  Y+ +       P   ++  ++ +
Sbjct:  94 VGSLSAFYPDLLNFKEADYELTAIRMIAKIPTIAAMSYKYSIGQPFIYPDNALDFTENFL 153

Query: 250 GMRLARSL-GFELNEF--DELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGL 306
            M  A     +++N    + L +++ +LHADHE  N S   VR+ GS+ ++P+   + G+
Sbjct: 154 HMMFATPCEKYKVNPIIKNALNKIF-ILHADHEQ-NASTSTVRIAGSSGANPFACVSTGI 211

Query: 307 NGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHV--IPGFGHAVL 364
             L GP HG AN+ V    + M +++G    ++EN+ +   +   +     + GFGH V 
Sbjct: 212 ASLWGPAHGGANEAV----INMLKEIG----SSENIPKYIAKAKDKNDPFRLMGFGHRVY 263

Query: 365 RRTDPRYTAQREFA------LKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQH 418
           +  D R    +E        L  L  + + Q+  +L  +  +  +E    +  +PNVD +
Sbjct: 264 KNYDLRAAVLKETCKEVLKELGQLDGNPLLQIAIELEAIALK--DEYFIERKLYPNVDFY 321

Query: 419 SGILLRYYGLVESNFYTVLFGVSRALGTLS 448
           SGI+ +  G + S  +TVLF ++R +G ++
Sbjct: 322 SGIIYKAMG-IPSQMFTVLFAIARTVGWMA 350


ref|YP_188831.1| citrate synthase [Staphylococcus epidermidis RP62A]
gb|AAW54630.1| citrate synthase [Staphylococcus epidermidis RP62A]
(373 aa)

Score: 86 bits (212), Expect: 1.80685e-15
Length: 328, Idn/Pos/Gap = 87/144/30 (26%/43%/9%)

Query: 127 EGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLL 186
           E +++LL    +P E+++  + + L     +   V +  +E   + +HPMT    +VS +
Sbjct:  43 EEIIFLLWNYRLPNENELSELKEKLFDYMTLNNRVYKHFEEYVTDHVHPMTALRTSVSYV 102

Query: 187 QHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKH--VPAEKIE 244
            H    AE  +         E   + A+ + A++ ++     R     GK    P  ++ 
Sbjct: 103 AHFDPEAENESD--------ENKYDRAIRIQAKIASLVTAFAR--VRDGKEPVKPNSELS 152

Query: 245 KVDDMGMRLARSLGFELNEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAA 304
              +    L   L  E+    E     L+LHADHE  N SA   R   S+LSD Y    A
Sbjct: 153 YAANFLYMLRGELPTEVEV--EAFNKALILHADHEL-NASAFTARCAVSSLSDMYSGVVA 209

Query: 305 GLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVL 364
            +  L GPLHG AN+ V    + M +++G    + +N+     E       I GFGH V 
Sbjct: 210 AIGSLKGPLHGGANERV----MSMLKEIG----SIDNVDHYLDERFANKDKIMGFGHRVY 261

Query: 365 RRTDPRYTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLR 424
           +  DPR    RE + K        +L      +  R+ EE+G +    PNVD  S  +  
Sbjct: 262 KDGDPRAKYLREMSRKITEETGQSELFEMSLAIEKRMKEEKGLI----PNVDFFSATV-- 315

Query: 425 YYGL-VESNFYTVLFGVSRALGTLSSLV 451
           Y+ + +  + +T +F VSR  G ++ ++
Sbjct: 316 YHSMNIPHDLFTPIFAVSRTSGWIAHIL 343


emb|CAB96384.1| citrate synthase [male-killing Rickettsia from Adalia bipunctata]
(355 aa)

Score: 86 bits (212), Expect: 1.88382e-15
Length: 369, Idn/Pos/Gap = 91/167/60 (24%/45%/16%)

Query: 100 IRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPP 159
           +R+RG+ I          K   E+     + +LL+ GE+P+  Q      +  ++ AV  
Sbjct:  22 LRYRGYDI----------KDLAEKSDFLEVAYLLIYGELPSSEQY----NNFTKKVAV--  65

Query: 160 EVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLE-------- 211
                   L +ER+H + Q     +       MA   A     S F+   L         
Sbjct:  66 ------HSLVNERLHYLFQ-----TFCSSSHPMAIMLAAVGSLSAFYPDLLNFKEADYEL 114

Query: 212 DALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDM--GMRLARSLGFELNEF--DEL 267
            A+ +IA++P +AA  Y+ +       P   ++  ++    M  A    +++N    + L
Sbjct: 115 TAIRMIAKIPTIAAMSYKYSIGQPFIYPDNSLDFTENFLHMMFAAPCEKYKVNPIIKNAL 174

Query: 268 MRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQ 327
            +++ +LHADHE  N S   VR+ GS+ ++P+   + G+  L GP HG AN+ V    + 
Sbjct: 175 NKIF-ILHADHEQ-NASTSTVRIAGSSGANPFACVSTGIASLWGPAHGGANEAV----IN 228

Query: 328 MKEKLGNRPMTTENLRELCWETLREGHV--IPGFGHAVLRRTDPRYTAQREFA------L 379
           M +++G    ++EN+ +   +   +     + GFGH V +  D R    +E        L
Sbjct: 229 MLKEIG----SSENIPKYIAKAKDKNDPFRLMGFGHRVYKNYDLRAAVLKETCKEVLKEL 284

Query: 380 KHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFG 439
             L  + + Q+  +L  +  +  +E    +  +PNVD +SGI+ +  G + S  +TVLF 
Sbjct: 285 GQLDGNPLLQIAIELEAIALK--DEYFIERKLYPNVDFYSGIIYKAMG-IPSQMFTVLFA 341

Query: 440 VSRALGTLS 448
           ++R +G ++
Sbjct: 342 IARTVGWMA 350


ref|ZP_00054766.1| COG0372: Citrate synthase [Magnetospirillum magnetotacticum MS-1]
(438 aa)

Score: 86 bits (212), Expect: 1.8996e-15
Length: 348, Idn/Pos/Gap = 91/155/33 (26%/44%/9%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +L+L GE+P   Q      D+   + V  ++         +  HPM      V  +    
Sbjct:  96 YLILKGELPNAEQKTKFEFDIAHHSMVHEQINFFFRGFRRDS-HPMAVLCGVVGAMA--- 151

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMG 250
               A+   +       + +  +  L+A++P + A  Y+         P  K+   ++  
Sbjct: 152 ----AFYHDSIDINDPHHRMVASYRLVAKMPTIVAWAYKYAQGQPFMFPQNKLSYSENFL 207

Query: 251 MRLARSLGFELNEFDELMRLY---LVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLN 307
             +  +   E      L R     L+LHADHE  N S   VRL GS+ ++P+   AAG+ 
Sbjct: 208 HMMYATPCEEYKVSPVLARAMDRILILHADHEQ-NASTSTVRLAGSSGANPFACIAAGIA 266

Query: 308 GLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRT 367
            L GP HG AN+ V    LQM  ++G+     E +++   +   +   + GFGH V +  
Sbjct: 267 SLWGPAHGGANEAV----LQMLHEIGSVERIPEFIKKA--KDKDDPFRLMGFGHRVYKNY 320

Query: 368 DPRYTAQREFALKHLP----HDE-MFQLVSKLYEVVPRVLEEQGKVKNP-WPNVDQHSGI 421
           DPR    ++   + L     HDE + +L  +L  +    LE+   V+   +PNVD +SGI
Sbjct: 321 DPRAKIMQKTCHEVLSELGVHDEPLLKLAMELERI---ALEDPYFVERKLFPNVDFYSGI 377

Query: 422 LLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPKSV 466
           + R  G + +  +T LF ++R +G ++   W+  L  P   I RP+ +
Sbjct: 378 IFRAMG-IPTQVFTCLFALARTVGWIAQ--WNEMLTDPDQKIGRPRQL 422


ref|NP_377788.1| hypothetical citrate synthase [Sulfolobus tokodaii str. 7]
dbj|BAB66897.1| 378aa long hypothetical citrate synthase [Sulfolobus tokodaii str. 7]
(378 aa)

Score: 86 bits (212), Expect: 1.93157e-15
Length: 387, Idn/Pos/Gap = 105/170/62 (27%/43%/16%)

Query:  82 RSLKAMVYETSLLDPQEGI----RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGE 137
           R L+ ++ +T+ L   +GI    R+RG+ I +   L+  A         E L+ L+L GE
Sbjct:   7 RGLENVIIKTTGLTYIDGINGILRYRGYDIND---LVNYASY-------EELIHLMLYGE  56

Query: 138 IPTESQVESVCQDLKRRAAVPPEVLRLLDELPH--ERMHPM-TQFSVAVSLLQHESKMAE 194
           +P   Q+  +   +     VP +V+  +  +P   + +  M T F +  S+  ++ K   
Sbjct:  57 LPNRQQLNQIKGIINESFEVPEQVISTIFSMPRNCDAIGMMETAFGILASI--YDPKWNR 114

Query: 195 AYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLA 254
           A  +            E A+ +IA+   + A IYR        +P       +     LA
Sbjct: 115 ATNK------------ELAVQIIAKTATITANIYRAKEGLKPKIPEPSESYAESF---LA 159

Query: 255 RSLGFE-LNEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPL 313
            + G +   E  + M   L+L+ DHE    S  A  +  S LSD Y    A L  L GPL
Sbjct: 160 ATFGKKPTQEEIKAMDASLILYTDHEV-PASTTAALVASSTLSDMYSCIVAALAALKGPL 218

Query: 314 HGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHV-IPGFGHAVLRRTDPRY- 371
           HG A +E  +  +++         + EN  +   E + +G   + GFGH V +  DPR  
Sbjct: 219 HGGAAEEAFKQFVEIG--------SVENADKWFEEKIIKGKSRLMGFGHRVYKTYDPRAK 270

Query: 372 ---TAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQG----KVKNPWPNVDQHSGILLR 424
              T  + FA K+       + V K YE+  R+ E+ G      K+ +PN D +SGI+  
Sbjct: 271 IFKTLAKSFAEKN-------ENVKKYYEIAERI-EKLGVDTFGSKHIYPNTDFYSGIVFY 322

Query: 425 YYGLVESNFYTVLFGVSRALGTLSSLV 451
             G      +T LF +SR LG L+ ++
Sbjct: 323 ALGF-PIYMFTSLFALSRVLGWLAHII 348


ref|NP_764926.1| citrate synthase II [Staphylococcus epidermidis ATCC 12228]
gb|AAO04970.1| citrate synthase II [Staphylococcus epidermidis ATCC 12228]
(373 aa)

Score: 86 bits (212), Expect: 1.99712e-15
Length: 327, Idn/Pos/Gap = 86/141/28 (26%/43%/8%)

Query: 127 EGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLL 186
           E +++LL    +P E+++  + + L     +   V +  +E   + +HPMT    +VS +
Sbjct:  43 EEIIFLLWNYRLPNENELSELKEKLFDYMTLNNRVYKHFEEYVTDHVHPMTALRTSVSYV 102

Query: 187 QHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKH--VPAEKIE 244
            H    AE  +         E   + A+ + A++ ++     R     GK    P  ++ 
Sbjct: 103 AHFDPEAENESD--------ENKYDRAIRIQAKIASLVTAFAR--VRDGKEPVKPNSELS 152

Query: 245 KVDDMGMRLARSLGFELNEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAA 304
              +    L   L  E+    E     L+LHADHE  N SA   R   S+LSD Y    A
Sbjct: 153 YAANFLYMLRGELPTEVEV--EAFNKALILHADHEL-NASAFTARCAVSSLSDMYSGVVA 209

Query: 305 GLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVL 364
            +  L GPLHG AN+ V    + M +++G    + +N+     E       I GFGH V 
Sbjct: 210 AIGSLKGPLHGGANERV----MSMLKEIG----SIDNVDHYLDERFANKDKIMGFGHRVY 261

Query: 365 RRTDPRYTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLR 424
           +  DPR    RE + K        +L      +  R+ EE+G +    PNVD  S  +  
Sbjct: 262 KDGDPRAKYLREMSRKITEETGQSELFEMSLAIEKRMKEEKGLI----PNVDFFSATVFH 317

Query: 425 YYGLVESNFYTVLFGVSRALGTLSSLV 451
               +  + +T +F VSR  G ++ ++
Sbjct: 318 SMN-IPHDLFTPIFAVSRTSGWIAHIL 343


gb|AAR17677.1| citrate synthase [Rickettsia bellii]
(384 aa)

Score: 86 bits (212), Expect: 2.04774e-15
Length: 400, Idn/Pos/Gap = 99/174/47 (24%/43%/11%)

Query:  80 GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEI 138
           G  S  +     + +D  +GI R RG+ I          K   E+     + +LL+ GE+
Sbjct:  17 GFMSTASCRSTITYIDGDQGILRHRGYDI----------KDLAEKSDFLEVAYLLIYGEL  66

Query: 139 PTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAV-SLLQHESKMAEAYA 197
           P         + +   A V  E L  L +      HPM     AV SL      +   + 
Sbjct:  67 PNNKLYNDFTKKVAHHALVN-ERLHYLFQTFCSSSHPMAIMLAAVGSLSAFYPDLLNFFK 125

Query: 198 QGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDD-MGMRLARS 256
           +   + T        A+ +IA++P +AA  Y+ +       P   ++  ++ + M  A  
Sbjct: 126 EADYELT--------AIRMIAKIPTIAAMSYKYSIGQPFVYPDNSLDFTENFLHMMFATP 177

Query: 257 L-GFELNEF--DELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPL 313
              +++N    + L +++ +LHADHE  N S   VR+ GS+ ++P+   + G+  L GP 
Sbjct: 178 CEKYKVNPVIKNALNKIF-ILHADHEQ-NASTSTVRIAGSSGANPFACVSTGIASLWGPA 235

Query: 314 HGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTA 373
           HG AN+ V+  L ++   + N P      ++       +   + GFGH V +  DPR   
Sbjct: 236 HGGANEAVINMLKEIGS-VENIPKYIAKAKD-----KNDNFRLMGFGHRVYKNYDPRAAV 289

Query: 374 QREFA------LKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYG 427
            +E        L  L ++ + Q+  +L  +  +  +E    +  +PNVD +SGI+ +  G
Sbjct: 290 LKETCKEVLKELGQLDNNPLLQIAIELEAIALK--DEYFIERKLYPNVDFYSGIIYKAMG 347

Query: 428 LVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPK 464
            +    +TVLF  +R +G ++   W      P   I RP+
Sbjct: 348 -IPPQMFTVLFATARTVGWMAQ--WKEMHEDPEQKISRPR 384


gb|AAL52017.1| CITRATE SYNTHASE [Brucella melitensis 16M]
ref|NP_539753.1| CITRATE SYNTHASE [Brucella melitensis 16M]
pir||AF3356 citrate (si)-synthase (EC 4.1.3.7) [imported] - Brucella melitensis (strain 16M)
(437 aa)

Score: 85 bits (211), Expect: 2.35981e-15
Length: 364, Idn/Pos/Gap = 97/156/61 (26%/42%/16%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LLL GE+PT +Q       + R   +  ++ +       +  HPM   +V V  L   S
Sbjct:  95 YLLLYGELPTATQKADFDYRVTRHTMLHEQMTKFFTGFRRD-AHPM---AVMVGCLGAMS 150

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYR------------------NTF 232
               A+   +   T     +  ++ LIA++P +AA  Y+                  N  
Sbjct: 151 ----AFYHDSTDITDPHQRMVASIRLIAKVPTLAAMAYKYHIGQPFVYPKNDLDFASNFL 206

Query: 233 HGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVLHADHEGGNVSAHAVRLVG 292
           H    VP E+  KV+ +   LAR+           M    +LHADHE  N S   VRL G
Sbjct: 207 HMCFTVPCEEY-KVNPV---LARA-----------MDRIFILHADHEQ-NASTSTVRLAG 250

Query: 293 SALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLRE 352
           S+ ++P+   AAG+  L GP HG AN+      L M  ++G+     E +     +   +
Sbjct: 251 SSGANPFACIAAGVACLWGPAHGGANEAA----LNMLSEIGSVDRIPEYIARA--KDKND 304

Query: 353 GHVIPGFGHAVLRRTDPRY-----TAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGK 407
              + GFGH V +  DPR      T         +  D +  +  +L  +   + +E   
Sbjct: 305 PFRLMGFGHRVYKNYDPRAKIMQKTCHEVLGELGIKDDPLLDVAMELERIA--LTDEYFI 362

Query: 408 VKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPK 464
            K  +PN+D +SGI L+  G   +  +TVLF ++R +G ++   W   +  P   I RP+
Sbjct: 363 EKKLYPNIDFYSGITLKALGF-PTEMFTVLFALARTVGWVAQ--WKEMIEDPQQKIGRPR 419

Query: 465 SVTT 468
            + T
Sbjct: 420 QLYT 423


gb|AAN30068.1| citrate synthase [Brucella suis 1330]
ref|NP_698153.1| citrate synthase [Brucella suis 1330]
(430 aa)

Score: 85 bits (211), Expect: 2.54384e-15
Length: 364, Idn/Pos/Gap = 97/156/61 (26%/42%/16%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LLL GE+PT +Q       + R   +  ++ +       +  HPM   +V V  L   S
Sbjct:  88 YLLLYGELPTATQKADFDYRVTRHTMLHEQMTKFFTGFRRD-AHPM---AVMVGCLGAMS 143

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYR------------------NTF 232
               A+   +   T     +  ++ LIA++P +AA  Y+                  N  
Sbjct: 144 ----AFYHDSTDITDPHQRMVASIRLIAKVPTLAAMAYKYHIGQPFVYPKNDLDFASNFL 199

Query: 233 HGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVLHADHEGGNVSAHAVRLVG 292
           H    VP E+  KV+ +   LAR+           M    +LHADHE  N S   VRL G
Sbjct: 200 HMCFTVPCEEY-KVNPV---LARA-----------MDRIFILHADHEQ-NASTSTVRLAG 243

Query: 293 SALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLRE 352
           S+ ++P+   AAG+  L GP HG AN+      L M  ++G+     E +     +   +
Sbjct: 244 SSGANPFACIAAGVACLWGPAHGGANEAA----LNMLSEIGSVDRIPEYIARA--KDKND 297

Query: 353 GHVIPGFGHAVLRRTDPRY-----TAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGK 407
              + GFGH V +  DPR      T         +  D +  +  +L  +   + +E   
Sbjct: 298 PFRLMGFGHRVYKNYDPRAKIMQKTCHEVLGELGIKDDPLLDVAMELERIA--LTDEYFI 355

Query: 408 VKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPK 464
            K  +PN+D +SGI L+  G   +  +TVLF ++R +G ++   W   +  P   I RP+
Sbjct: 356 EKKLYPNIDFYSGITLKALGF-PTEMFTVLFALARTVGWVAQ--WKEMIEDPQQKIGRPR 412

Query: 465 SVTT 468
            + T
Sbjct: 413 QLYT 416


ref|YP_221854.1| GltA, citrate synthase [Brucella abortus biovar 1 str. 9-941]
gb|AAX74493.1| GltA, citrate synthase [Brucella abortus biovar 1 str. 9-941]
(430 aa)

Score: 85 bits (211), Expect: 2.65222e-15
Length: 364, Idn/Pos/Gap = 97/156/61 (26%/42%/16%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LLL GE+PT +Q       + R   +  ++ +       +  HPM   +V V  L   S
Sbjct:  88 YLLLYGELPTATQKADFDYRVTRHTMLHEQMTKFFTGFRRD-AHPM---AVMVGCLGAMS 143

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYR------------------NTF 232
               A+   +   T     +  ++ LIA++P +AA  Y+                  N  
Sbjct: 144 ----AFYHDSTDITDPHQRMVASIRLIAKVPTLAAMAYKYHIGQPFVYPKNNLDFASNFL 199

Query: 233 HGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVLHADHEGGNVSAHAVRLVG 292
           H    VP E+  KV+ +   LAR+           M    +LHADHE  N S   VRL G
Sbjct: 200 HMCFTVPCEEY-KVNPV---LARA-----------MDRIFILHADHEQ-NASTSTVRLAG 243

Query: 293 SALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLRE 352
           S+ ++P+   AAG+  L GP HG AN+      L M  ++G+     E +     +   +
Sbjct: 244 SSGANPFACIAAGVACLWGPAHGGANEAA----LNMLSEIGSVDRIPEYIARA--KDKND 297

Query: 353 GHVIPGFGHAVLRRTDPRY-----TAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGK 407
              + GFGH V +  DPR      T         +  D +  +  +L  +   + +E   
Sbjct: 298 PFRLMGFGHRVYKNYDPRAKIMQKTCHEVLGELGIKDDPLLDVAMELERIA--LTDEYFI 355

Query: 408 VKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPK 464
            K  +PN+D +SGI L+  G   +  +TVLF ++R +G ++   W   +  P   I RP+
Sbjct: 356 EKKLYPNIDFYSGITLKALGF-PTEMFTVLFALARTVGWVAQ--WKEMIEDPQQKIGRPR 412

Query: 465 SVTT 468
            + T
Sbjct: 413 QLYT 416


ref|YP_155815.1| Citrate synthase [Idiomarina loihiensis L2TR]
gb|AAV82266.1| Citrate synthase [Idiomarina loihiensis L2TR]
(374 aa)

Score: 85 bits (210), Expect: 3.3502e-15
Length: 365, Idn/Pos/Gap = 97/154/53 (26%/42%/14%)

Query:  99 GIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVP 158
           G+ +RG+ I E            E+   E + +LL  GE+P + Q+    + LK    +P
Sbjct:  30 GLTYRGYDISEL----------AEKVSFEEVAYLLAKGELPNKQQLTDYKKRLKSLRTLP  79

Query: 159 PEVLRLLDELPHERMHPMTQFSVAVSLL---QHESKMAEAYAQGAPKSTFWEYCLEDALT 215
            EV  +L+ +P +  HPM       S+L   + E    EA               +D + 
Sbjct:  80 QEVKDVLERIP-KSAHPMDVMRTGCSMLGNLETEESFDEA---------------DDHIE 123

Query: 216 -LIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLG----FELNEFDELMRL 270
            L+A  P +    YR T H G  +  +  E  + +G    R L      EL+    +M  
Sbjct: 124 RLLATFPGIVLYWYRYT-HDGVRIDTDSEE--ESIGAHFLRLLHDKAPSELHA--AVMNT 178

Query: 271 YLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKE 330
            L+L+A+HE  N S    R+  S LSD +      +  L GPLHG AN+  +  +  MK+
Sbjct: 179 SLILYAEHEF-NASTFTARVCASTLSDIHSCVTGAIGSLRGPLHGGANEAAMELIEGMKD 237

Query: 331 KLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQL 390
                    ++  +     L     I GFGHA+ R  DPR    + ++ K    +E+   
Sbjct: 238 --------ADDAEQKLKGMLERKEKIMGFGHAIYRDFDPRNDVIKAWSKKL--SEEVGD- 286

Query: 391 VSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSL 450
            S+LY+V  R  +     K  +PN D        Y G + +  +T +F +SR  G  + +
Sbjct: 287 -SRLYDVSVRCEKVMWDEKKLFPNADFFHASAYHYMG-IPTKLFTPIFVMSRVTGWTAHV 344

Query: 451 VWDRA 455
              RA
Sbjct: 345 KEQRA 349


ref|NP_693190.1| citrate synthase III [Oceanobacillus iheyensis HTE831]
dbj|BAC14225.1| citrate synthase III [Oceanobacillus iheyensis HTE831]
(368 aa)

Score: 85 bits (210), Expect: 3.40658e-15
Length: 318, Idn/Pos/Gap = 86/144/28 (27%/45%/8%)

Query: 136 GEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEA 195
           G++P + ++    + LK    VP  VL +L  LP E  HPM     A+S+L    K  E 
Sbjct:  57 GDLPKKVEITKTEKLLKDHYEVPQAVLDILKLLPKE-THPMDGMRTALSVLAGYDKNIED 115

Query: 196 YAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLAR 255
            +  A K        + A  L+ +LP +    YR   +     PA ++    +    L  
Sbjct: 116 RSASANK--------DRAYQLLGQLPTITVNSYRILNNQEVVQPATELSYSANF---LYM 164

Query: 256 SLGFELNEFD-ELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLH 314
             G E ++   E+    L+L+++HE  N S    R++ S  SD Y +    ++ L G LH
Sbjct: 165 ITGKEPSDLQVEIFDRLLLLYSEHEMPN-STFTARVISSTNSDMYGALTGAISSLKGNLH 223

Query: 315 GLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAV-LRRTDPRYTA 373
           G AN+ V+  L        N   T +   +L ++ L     I GFGH V +++ DPR   
Sbjct: 224 GGANEAVMYML--------NEVETADEFEQLLYKKLENKEKIMGFGHRVYMKKMDPRALI 275

Query: 374 QREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNF 433
            +E ALK L   +    + ++ E    V++++   K  +PN+D ++  +    G+  S  
Sbjct: 276 TKE-ALKKLCEKDNDYTLLEMCEAGEEVMKKE---KGLYPNLDYYAAPVYWKLGIPIS-L 330

Query: 434 YTVLFGVSRALGTLSSLV 451
           YT +F  +R  G  + +V
Sbjct: 331 YTPIFFSARTAGLAAHIV 348


gb|AAV90587.1| citrate synthase [Zymomonas mobilis subsp. mobilis ZM4]
ref|YP_163698.1| citrate synthase [Zymomonas mobilis subsp. mobilis ZM4]
(429 aa)

Score: 85 bits (209), Expect: 3.86076e-15
Length: 403, Idn/Pos/Gap = 107/170/47 (26%/42%/11%)

Query:  80 GMRSLKAMVYETSLLDPQEGIR-FRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEI 138
           G  S  +   + + +D ++GI  +RG+ I +            +   PE + +LLL GE+
Sbjct:  47 GFLSTASCQSKITYVDGEKGILLYRGYPIEQLAE---------KSSFPE-VAYLLLHGEL  96

Query: 139 PTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQ 198
           P      S   D+     +  E L           HPM      V  L   +   EA   
Sbjct:  97 PKADDF-STFSDVITHHTMVNEQLSAFYRGFRRDAHPMAVLCGVVGALS--AFYPEAIHI 153

Query: 199 GAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLG 258
             P        +     L+A+LP +AA  Y+ +       P   +  V +  +R+  S+ 
Sbjct: 154 HDPAQR-----MASCHRLLAKLPTIAAMAYKYSVGQPFVYPDNSLSYVGNF-LRMTFSVP 207

Query: 259 FELNEFDELMRLYL----VLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLH 314
            E    D L+   L    +LHADHE  N S   VRL GS+ ++PY   AAG+  L GP H
Sbjct: 208 AEPYHVDPLIESALNKIFILHADHEQ-NASTSTVRLAGSSGANPYACIAAGIACLWGPSH 266

Query: 315 GLANQEVLRWLLQMKEKLGNRPMTTENLRELC--WETLREGHVIPGFGHAVLRRTDPRYT 372
           G AN+      L M +++G    T EN+       +   +   + GFGH + +  DPR  
Sbjct: 267 GGANEAT----LAMLKEIG----TPENIPHFIDRAKDRNDPFRLMGFGHRLYKNYDPRAR 318

Query: 373 AQREFALKHL----PHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGL 428
              + A   L     ++ +F     L E+  +  +     +  +PNVD +SG++L   G 
Sbjct: 319 VLAKTAAAILDKTGANNPIFDTARALEEIARK--DSYFIERKLYPNVDFYSGLILSAIGF 376

Query: 429 VESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPKSVTT 468
             S F T LF ++R  G ++   W+  +  P   I RP+ + T
Sbjct: 377 PTSMF-TALFALARTAGWMAQ--WNEMITDPEQKIGRPRQIYT 416


ref|NP_715984.1| methylcitrate synthase [Shewanella oneidensis MR-1]
gb|AAN53429.1| methylcitrate synthase [Shewanella oneidensis MR-1]
(375 aa)

Score: 84 bits (208), Expect: 5.30116e-15
Length: 359, Idn/Pos/Gap = 89/156/41 (24%/43%/11%)

Query:  99 GIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVP 158
           G+ +RG+ +          K   E    E + +L+L GE+PT +Q+ +    LK    +P
Sbjct:  31 GLTYRGYDV----------KDLAENATFEEVAYLILYGELPTTAQLAAYKTKLKGMRGLP  80

Query: 159 PEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIA 218
             +  +L+ +P +  HPM       S+L +     EA    + +S         A  L+A
Sbjct:  81 QALKEVLERIPAD-AHPMDVMRTGCSMLGN----LEAEHSFSEQSQI-------ADRLLA 128

Query: 219 RLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNE--FDELMRLYLVLHA 276
             P++    YR + H G  +  E  +  D +G      L  +       ++M + L+L+A
Sbjct: 129 AFPSIICYWYRFS-HDGVRIDTETDD--DQIGAHFLHLLHGKAPSALHTKVMDVSLILYA 185

Query: 277 DHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRP 336
           +HE  N S    R+  S LSD +      +  L GPLHG AN+  +  +  MK++     
Sbjct: 186 EHEF-NASTFTARVCASTLSDMHSCVTGAIGSLRGPLHGGANEAAMELIQDMKDE----- 239

Query: 337 MTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSKLYE 396
               + R++    L     I GFGHA+ R +DPR    +E++ K L  D     + ++  
Sbjct: 240 ---ADARDVLMGKLERKEKIMGFGHAIYRDSDPRNAIIKEWSEK-LAADYGDDRLYRVSV 295

Query: 397 VVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRA 455
               ++ EQ K+   + N D        + G + +  +T +F  SR  G  + ++  R+
Sbjct: 296 ACEALMWEQKKL---FCNADFFHASAYHFMG-IPTKLFTPIFVCSRVTGWTAHVMEQRS 350


ref|ZP_00356499.1| COG0372: Citrate synthase [Chloroflexus aurantiacus]
(428 aa)

Score: 84 bits (208), Expect: 6.21184e-15
Length: 418, Idn/Pos/Gap = 109/185/53 (26%/44%/12%)

Query:  63 RFGEEVLDACTVNQAYGGMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQRLLPRAKPSG 121
           +  E+     + + AY    S K+ +   + +D  +GI  +RG+ I +            
Sbjct:  35 KVSEDDFGLMSYDPAYLNTASCKSSI---TYIDGDKGILEYRGYPIEQL----------A  81

Query: 122 EQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPM---TQ 178
           EQ     + +LLL GE+P++ ++      + R   +   ++ L+    ++  HPM     
Sbjct:  82 EQSSYLEVAYLLLYGELPSKERLAWWEYRISRHLFLHNSLVELIQAFRYD-AHPMGILIS 140

Query: 179 FSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHV 238
              A+S L  E+K    +     +   W         +I ++P +AA  YR+      ++
Sbjct: 141 SVAAMSTLYPEAK--NIHDPAVREKQIWR--------IIGQIPTIAAFAYRHRIGRPFNL 190

Query: 239 PAEKIEKVDDM--GMRLARSLGFELNE-FDELMRLYLVLHADHEGGNVSAHAVRLVGSAL 295
           P   +    ++   M       +E+N    + + +  +LHADHE  N S   +R VGS+ 
Sbjct: 191 PDSSLSYTANLLYMMDYMNQREYEVNPVLAKALDVLFILHADHEQ-NCSTSVMRSVGSSH 249

Query: 296 SDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHV 355
           +DPY + AA    L GPLHG AN+ VLR L Q+     N P   E +++     +R    
Sbjct: 250 ADPYNALAAAAAALYGPLHGGANEAVLRMLQQIGHP-KNVPAFIERVKK---GEMR---- 301

Query: 356 IPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKV-KNPWPN 414
           + GFGH V +  DPR    R+ A +         L+    E+    LE++  + +  +PN
Sbjct: 302 LMGFGHRVYKNYDPRAKIIRKIAHEVFAATAANPLLDVAMELERTALEDEYFISRKLYPN 361

Query: 415 VDQHSGIL---LRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLP---IERPKSV 466
           VD +SG++   LR+       ++  LF + RA G L+   W   L  P   I RP+ V
Sbjct: 362 VDFYSGLIYQALRF----PIEYFPFLFAIPRASGWLAQ--WIEMLEDPEQKITRPRQV 413


dbj|BAB07643.1| citrate synthase III [Bacillus halodurans C-125]
ref|NP_244792.1| citrate synthase III [Bacillus halodurans C-125]
pir||D84140 citrate synthase III mmgD [imported] - Bacillus halodurans  (strain C-125)
(368 aa)

Score: 84 bits (207), Expect: 6.42266e-15
Length: 336, Idn/Pos/Gap = 92/155/31 (27%/46%/9%)

Query: 132 LLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESK 191
           LLL G +P  S+  ++   LK+   +P  V+ +L  LP E  HPM      +S L    K
Sbjct:  53 LLLDGTLPNASEKSALEDTLKKHYDIPSYVMEILSLLP-ETTHPMDGLRTGLSALSSVDK 111

Query: 192 MAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGM 251
             E  +  A K+         A  L+ +LPA+    YR   +G K V  + +  +     
Sbjct: 112 EIENRSTEANKAR--------AYKLLGKLPAITVNSYR-LINGLKTV--QPVPTLSYSAN 160

Query: 252 RLARSLGFELNEFD-ELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLA 310
            L    G E   F+ ++    L+L+++HE  N S    R++ S  SD Y +   G+  L 
Sbjct: 161 FLYMITGKEPKPFEAKIFDRSLLLYSEHEMPN-STFTARVIASTHSDLYGALTGGVASLK 219

Query: 311 GPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAV-LRRTDP 369
           G LHG AN+ V+ ++LQ  +       +    ++L  + L     + GFGH V +++ DP
Sbjct: 220 GNLHGGANEAVM-YMLQSVD-------SAAEFQQLIQKKLVNKEKVMGFGHRVYMKKMDP 271

Query: 370 RYTAQREFALKHLPHDEM-FQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGL 428
           R    +E +LK L   +  + L+ +       +LEE+G     +PN+D ++  +    G 
Sbjct: 272 RALEMKE-SLKQLCEKKGDYSLLDRCEAGEKTMLEEKGL----YPNLDYYAAPVYWMLG- 325

Query: 429 VESNFYTVLFGVSRALGTLSSLVWDRALGLPIERPK 464
           +    YT +F  +R  G L++ V ++     I RP+
Sbjct: 326 IPIELYTPIFFTARTAG-LAAHVMEQHQNNRIFRPR 360


gb|AAS89947.1| GltA [Bartonella rattimassiliensis]
(338 aa)

Score: 84 bits (207), Expect: 7.09903e-15
Length: 319, Idn/Pos/Gap = 84/148/28 (26%/46%/8%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LLL GE+PT+ +     Q + +   V  +  R       +  HPM   +V VS L   S
Sbjct:  39 YLLLYGELPTQQEKSDFDQCIMQHTMVHEQFARFFHGFRRDS-HPM---AVMVSCLGAMS  94

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMG 250
               A+   +   T  +  +  ++ LI+++P +AA  Y+ +       P   +    +  
Sbjct:  95 ----AFYHDSIDITDPQQRMIASIRLISKVPTLAAMAYKYSIGQPFVYPRNDLSYAANF- 149

Query: 251 MRLARSLGFELNEFDEL----MRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGL 306
           +R+  ++  E  + + +    M    +LHADHE  N S   VRL GS+ ++P+   AAG+
Sbjct: 150 LRMCFAVPCEEYKTNPVLARAMDQIFILHADHEQ-NASTSTVRLAGSSGANPFACIAAGV 208

Query: 307 NGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRR 366
             L GP HG AN+  L+    M +++G+     E +     +   +   + GFGH V + 
Sbjct: 209 ACLWGPAHGGANEACLK----MLQEIGSIKRIPEFIARA--KDKNDPFRLIGFGHRVYKN 262

Query: 367 TDPRY-----TAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGI 421
            DPR      T  +     ++  D +  +  +L ++   + +E    K  +PNVD +SGI
Sbjct: 263 YDPRAKIMQKTCHKVLKELNIQDDPLLDIAIELEKIA--LSDEYFIEKKLYPNVDFYSGI 320

Query: 422 LLRYYGLVESNFYTVLFGV 440
           +L+  G   +  +TVLF +
Sbjct: 321 ILKALGF-PTEMFTVLFAL 338


gb|AAP92456.1| citrate synthase [Rickettsia aeschlimannii]
(386 aa)

Score: 84 bits (207), Expect: 7.526e-15
Length: 406, Idn/Pos/Gap = 96/177/63 (23%/43%/15%)

Query:  60 VRERFGEEVLDACTVNQAYG------GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQR 112
           ++   GE+V+D   V+          G  S  +     + +D  +GI R RG+ I     
Sbjct:  19 LKASIGEDVIDISRVSAEADCFTYDPGFMSTASCQSTITYIDGDKGILRHRGYDI-----  73

Query: 113 LLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHER 172
                K   E+     + +LL+ GE+P   Q  +  + +   + V            +ER
Sbjct:  74 -----KDLAEKSDFLEVAYLLIYGELPNGEQYNNFTKQVAHHSLV------------NER 116

Query: 173 MHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLE--------DALTLIARLPAVA 224
           +H + Q     +       MA   A     S F+   L          A+ +IA++P +A
Sbjct: 117 LHYLFQ-----TFCSSSHPMAIMLAAVGSLSAFYPDLLNFKEADYELTAIRMIAKIPTIA 171

Query: 225 ARIYRNTFHGGKHVPAEKIEKVDD-MGMRLARS-LGFELNEF--DELMRLYLVLHADHEG 280
           A  Y+ +       P   ++  ++ + M  A     +++N    + L +++ +LHADHE 
Sbjct: 172 AMSYKYSIGQPFIYPDNSLDFTENFLHMMFATPCTKYKVNPIIKNALNKIF-ILHADHEQ 230

Query: 281 GNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTE 340
            N S   VR+ GS+ ++P+   + G+  L GP HG AN+ V    + M +++G+     +
Sbjct: 231 -NASTSTVRIAGSSGANPFACISTGIASLWGPAHGGANEVV----INMLKEIGSSEYIPK 285

Query: 341 NLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFA------LKHLPHDEMFQLVSKL 394
            + +   +   +   + GFGH V +  DPR    +E        L  L ++ + Q+  +L
Sbjct: 286 YIAKA--KDKNDPFRLMGFGHRVYKNYDPRAAVLKETCKEVLKELGQLDNNPLLQIAIEL 343

Query: 395 YEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGV 440
             +  +  +E    +  +PNVD +SGI+ +  G + S  +TVLF +
Sbjct: 344 EAIALK--DEYFIERKLYPNVDFYSGIIYKAMG-IPSQMFTVLFAI 386


gb|AAL79563.1| citrate synthase [Anaplasma platys]
(411 aa)

Score: 83 bits (206), Expect: 8.96728e-15
Length: 397, Idn/Pos/Gap = 105/167/44 (26%/42%/11%)

Query:  80 GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEI 138
           G  S  A   E + +D ++GI R RG  I         A   G +     +  LLL G +
Sbjct:  45 GFMSTAACSSEITFIDGEKGILRHRGLDI---------ADLIGIKGGFCSVAHLLLYGVL  95

Query: 139 PTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQ 198
           P+++  E     +  + A+  +VL ++     +  HPM       S L        A   
Sbjct:  96 PSDTVFEQFLAAIGAQHALSSDVLGVISSFRRD-AHPMAILMACFSTLA-------AKYH 147

Query: 199 GAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDD-MGMRLARSL 257
           G  +        E A+  IA++P++ A IY +        P   +    + + M      
Sbjct: 148 GDNRGN-----EELAVLAIAQVPSLVAAIYLHRMGLELVSPDPSLSYTGNFVKMMFGALE 202

Query: 258 GFELNEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLA 317
               +  +E +    ++HADHE  N S   VR+ GSA ++ +   AAG   L GP HG A
Sbjct: 203 KTRADAIEEALDAIFIMHADHEQ-NASTATVRMAGSAGTELFACLAAGTATLWGPAHGGA 261

Query: 318 NQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREF 377
           N+ V+R    M E +G+ P   E       +   +  ++ GFGH V +  DPR     + 
Sbjct: 262 NEAVIR----MLESIGS-PDKVEEFIGFVKDNNSKVRLM-GFGHRVYKSYDPRAKILGQI 315

Query: 378 ALKHLPH----DEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNF 433
           +   L +    DE+  +  +L      + +E    +  +PNVD +SGI+LR  G V    
Sbjct: 316 SRSVLDNLGCSDELLGVAEELERCA--LQDEYFVERKLYPNVDFYSGIVLRAMG-VPVEM 372

Query: 434 YTVLFGVSRALGTLSSLVWDRAL----GLPIERPKSV 466
           YT  F ++R  G +S   W   L     L I RP+ +
Sbjct: 373 YTTFFALARTAGWVSQ--WCELLRGSESLKICRPRQL 407


emb|CAH15736.1| 2-methylcitrate synthase [Legionella pneumophila str. Lens]
ref|YP_126842.1| 2-methylcitrate synthase [Legionella pneumophila str. Lens]
gb|AAD42885.1| PrpC [Legionella pneumophila]
(372 aa)

Score: 83 bits (206), Expect: 9.27162e-15
Length: 372, Idn/Pos/Gap = 93/169/46 (25%/45%/12%)

Query:  98 EGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAV 157
           +G+ +RG+SI +            E    E + +LL  GE+PT+ +++   + L     +
Sbjct:  26 KGLNYRGYSINDL----------AEYASFEEVAYLLHYGELPTQKELDVYIKKLVNLRHI  75

Query: 158 PPEVLRLLDELPHERMHPMTQFSVAVSLL---QHESKMAEAYAQGAPKSTFWEYCLEDAL 214
           P +VL+ + +L  +  HPM     A S L   + E    + Y              E A 
Sbjct:  76 P-DVLKTVLKLIPKNTHPMDVLRTACSFLGTIEPEENFKQQY--------------EIAD 120

Query: 215 TLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFD-ELMRLYLV 273
            L+A  P +    Y  T+H      +   E+    G  LA   G + ++ + ++M + L+
Sbjct: 121 RLLALFPGIMCYWY--TYHFKNKEISGLSEENTTGGHFLALLHGRKPSKIETDMMNVSLI 178

Query: 274 LHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLG 333
           L+A+HE  N S  A R+  + L+D Y +  + +  L GPLHG AN+      +++ E+  
Sbjct: 179 LYAEHEF-NASTFAARVTAATLADFYSAITSAIGTLRGPLHGGANEAA----MELIERFK 233

Query: 334 NRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSK 393
                   ++++    L    +I GFGH V    DPR    ++++ +    +E   L+  
Sbjct: 234 TPDEAAIGIKQM----LASKELIMGFGHRVYTTCDPRSDIIKKWSFRL--GEEKGNLL-- 285

Query: 394 LYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWD 453
           LY +  R+ E   + K  +PN+D +S     Y   + ++ +T +F +SR  G  S+ V++
Sbjct: 286 LYHISERIEEIMWQEKKLFPNLDFYSASAYHYCD-IPTHLFTPIFVMSRITG-WSAHVFE 343

Query: 454 RALGLPIERPKS 465
           +     + RP S
Sbjct: 344 QRANNKLIRPTS 355


gb|AAO48735.1| citrate synthase [Rickettsia sp. RDa420]
(362 aa)

Score: 83 bits (206), Expect: 9.3493e-15
Length: 371, Idn/Pos/Gap = 94/163/42 (25%/43%/11%)

Query:  80 GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEI 138
           G  S  +     + +D  +GI R RG+ I          K   E+     + +LL+ GE+
Sbjct:  22 GFMSTASCRSTITYIDGDQGILRHRGYDI----------KDLAEKSDFLEVAYLLIYGEL  71

Query: 139 PTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAV-SLLQHESKMAEAYA 197
           P   Q     + +   A V  E L  L +      HPM     AV SL      +   + 
Sbjct:  72 PNSKQYNDFTKKVAHHALVN-ERLHYLFQTFCSSSHPMAIMLAAVGSLSAFYPDLLNFFK 130

Query: 198 QGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDD-MGMRLARS 256
           +   + T        A+ +IA++P +AA  Y+ +       P   I+  ++ + M  A  
Sbjct: 131 EADYELT--------AIRMIAKIPTIAAMSYKYSIGQPFVYPDNSIDFTENFLHMMFATP 182

Query: 257 L-GFELNEF--DELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPL 313
              +++N    + L +++ +LHADHE  N S   VR+ GS+ ++P+   + G+  L GP 
Sbjct: 183 CEKYKVNPVIKNALNKIF-ILHADHEQ-NASTSTVRIAGSSGANPFACVSTGIASLWGPA 240

Query: 314 HGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTA 373
           HG AN+ V+  L ++   + N P      ++       +   + GFGH V +  DPR   
Sbjct: 241 HGGANEAVINMLKEIGS-VENIPKYIAKAKD-----KNDNFRLMGFGHRVYKNYDPRAAV 294

Query: 374 QREFA------LKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYG 427
            +E        L  L ++ + Q+  +L  +  +  +E    +  +PNVD +SGI+ +  G
Sbjct: 295 LKETCKEVLKELGQLDNNPLLQIAIELEAIALK--DEYFIERKLYPNVDFYSGIIYKAMG 352

Query: 428 LVESNFYTVLF 438
            +    +TVLF
Sbjct: 353 -IPPQMFTVLF 362


gb|AAL01666.1| citrate synthase [Ehrlichia sennetsu]
(398 aa)

Score: 83 bits (206), Expect: 9.42764e-15
Length: 349, Idn/Pos/Gap = 93/151/47 (26%/43%/13%)

Query: 113 LLPRAKPSGEQPLPEGLL---WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELP 169
           LL R  P  E       L   +LL+ G++P  +      + +K    +P  VL+ +   P
Sbjct:  58 LLHRGYPIEELAQTSDFLQVGYLLIDGKLPDSAATREFEERIKHVPQLPECVLKNIRSFP 117

Query: 170 HERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYR 229
               HPM   +V +S L   + +A  Y +            +  L L+A  P + A IYR
Sbjct: 118 -TSAHPM---AVLISAL---ASLASVYGEMDFN--------QKKLLLVAYTPWLIAHIYR 162

Query: 230 NTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDE-------LMRLYLVLHADHEGGN 282
                  H+ + +  + D   +RL  +  F    F E       ++    +LHADH G  
Sbjct: 163 -------HINSLEFVEPD---IRLPYTENFLYMMFGEKKPKDAEILDKIFILHADH-GQT 211

Query: 283 VSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENL 342
            S    R+V S+ + P  + +A    L GPLHG AN+ VL  L  + E       + E +
Sbjct: 212 ASTSVARMVVSSGASPIAACSAATASLWGPLHGGANERVLEMLRGIVE-------SGEKV 264

Query: 343 RELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDE-MFQLVSKLYEVVPRV 401
                   R+   + GFGH V +  DPR    ++ A   L  D  + +   +L  +  R 
Sbjct: 265 ENFIERVKRKEERLMGFGHRVYKNYDPRAAILKQKAHDVLKADSPILKTAGELETITAR- 323

Query: 402 LEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSL 450
            EE    +  +PNVD +SGI+L   G + S  +T +F ++R +G ++ +
Sbjct: 324 -EEYFLSRKLYPNVDFYSGIVLDALG-ISSCMFTPIFALARTVGWVAQI 370


ref|YP_129460.1| putative methylcitrate synthase [Photobacterium profundum SS9]
emb|CAG19658.1| putative methylcitrate synthase [Photobacterium profundum SS9]
(375 aa)

Score: 83 bits (206), Expect: 9.82926e-15
Length: 364, Idn/Pos/Gap = 95/154/51 (26%/42%/14%)

Query:  99 GIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVP 158
           G+ +RG+ I +            E    E + +LLL G++PT++Q+++    L     +P
Sbjct:  30 GLTYRGYDISDL----------AESADFEEVAYLLLKGKLPTQAQLDAYKTVLISYRGLP  79

Query: 159 PEVLRLLDELPHERMHPMTQFSVAVSLL---QHESKMAEAYAQGAPKSTFWEYCLEDALT 215
             +  +L+++P +  HPM       S+L   + E + +E Y              + A  
Sbjct:  80 LALKVVLEQIPAD-AHPMDVMRTGCSMLGNLEQEHEFSEEY--------------DKADR 124

Query: 216 LIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLG----FELNEFDELMRLY 271
           L+A  PA+    YR + HG   V  E     D +G    + L      EL++    M   
Sbjct: 125 LLALFPAIICYWYRYSHHG---VRIETYCDQDSLGGYFLKMLTDKSPSELHK--RAMHCS 179

Query: 272 LVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEK 331
           L+L+A+HE  N S  A R+  S LSD +   A  +  L GPLHG AN+  +  + Q +  
Sbjct: 180 LILYAEHEF-NASTFAARVCASTLSDLHSCIATAIGTLRGPLHGGANEAAMAMIEQWQ-- 236

Query: 332 LGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLV 391
                 TT+         L     I GFGHAV   +DPR    + ++   L  +E    V
Sbjct: 237 ------TTDEAEAGILTMLANKDKIMGFGHAVYSESDPRNVLIKRWS--KLLSEEADDAV 288

Query: 392 SKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLV 451
             LY +  RV     + K  + N D        +   + +  +T +F +SR  G  + + 
Sbjct: 289 --LYAISERVETVMKREKGLFCNADFFHASAYHFLN-IPTKLFTPIFVMSRLTGWAAHVF 345

Query: 452 WDRA 455
             RA
Sbjct: 346 EQRA 349


gb|AAQ85066.1| citrate synthase [Rickettsia sp. ARANHA]
(262 aa)

Score: 83 bits (206), Expect: 1.04205e-14
Length: 246, Idn/Pos/Gap = 65/126/21 (26%/51%/8%)

Query: 213 ALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDD-MGMRLARS-LGFELNEF--DELM 268
           A+ +IA++P +AA  Y+ +       P   ++  ++ + M  A     +++N    + L 
Sbjct:  26 AIRMIAKIPTIAAMSYKYSIGQPFIYPDNSLDFTENFLHMMFATPCTKYKVNPIIKNALN  85

Query: 269 RLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQM 328
           +++ +LHADHE  N S   VR+ GS+ ++P+   + G+  L GP HG AN+ V    + M
Sbjct:  86 KIF-ILHADHEQ-NASTSTVRIAGSSGANPFACISTGIASLWGPAHGGANEAV----INM 139

Query: 329 KEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFA------LKHL 382
            +++G+     + + +   +   +   + GFGH V +  DPR    +E        L  L
Sbjct: 140 LKEIGSSEYIPKYIAKA--KDKNDPFRLMGFGHRVYKNYDPRAAVLKETCKEVLKELGQL 197

Query: 383 PHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSR 442
            ++ + Q+  +L  +  +  +E    +  +PNVD +SGI+ +  G + S  +TVLF ++R
Sbjct: 198 DNNPLLQIAIELEAIALK--DEYFIERKLYPNVDFYSGIIYKAMG-IPSQMFTVLFAIAR 254

Query: 443 ALGTLS 448
            +G ++
Sbjct: 255 TVGWMA 260


gb|AAL01662.1| citrate synthase [Ehrlichia muris]
(416 aa)

Score: 83 bits (205), Expect: 1.34964e-14
Length: 427, Idn/Pos/Gap = 106/190/65 (24%/44%/15%)

Query:  42 LQEAVRSKIEPMRAQVHEVRERFGEEVLDACTVNQAYG------GMRSLKAMVYETSLLD  95
           ++EAV  +++  R ++  + +  G + +D  ++ +  G      G  S  A   + + +D
Sbjct:   2 IKEAVL-ELDDQRIKLPVLYDTNGNKAVDITSLYKDTGVLTYDPGFMSTAACESKITFID  60

Query:  96 PQEGIR-FRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRR 154
             +GI  +RG +I +          +G +   E +++LL  G  P+   +++    + + 
Sbjct:  61 GNKGILCYRGHNIVDLV--------NGNKSFVE-IIYLLFYGVFPSSEDLQNFTLQISQE 111

Query: 155 AAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDAL 214
              PP+V+  + +   +  HPM       S L      A  + + A K       L+ A 
Sbjct: 112 YT-PPQVVYDVIKAFSQDSHPMAILMACFSALA-----AYYHDREADKDE-----LKCAK 160

Query: 215 TLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFD--------- 265
             +A++ ++ A IYR       ++  +     D    +L+ S  F    FD         
Sbjct: 161 LAVAKIASIVALIYR-------YITNQDFITAD---TKLSYSENFVHMMFDISSYKFTQV 210

Query: 266 --ELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLR 323
             + + +  VLHADHE  N S   VRL GSA +D +    AG   L GP HG AN+ V+ 
Sbjct: 211 VAKALDIIFVLHADHEQ-NASTATVRLAGSAGADLFACLVAGTATLWGPAHGGANEAVIN 269

Query: 324 WLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLP 383
            L+ + EK  N     + +++   +T R    + GFGH V +  DPR     E   + L 
Sbjct: 270 MLMTI-EKPSNVKQFIQKVKDGS-KTTR----LMGFGHRVYKNYDPRAKMMCEICREVLN 323

Query: 384 ----HDEMFQLVSKLYEVVPRVLEEQGKV-KNPWPNVDQHSGILLRYYGLVESNFYTVLF 438
                D + ++  +L  +    L++   + +N +PNVD +SGI+L+  G +    +T LF
Sbjct: 324 DLGIDDPLLEVAVELENI---ALQDSYFIERNLYPNVDFYSGIVLKAIG-IPVKMFTTLF 379

Query: 439 GVSRALG 445
            ++R  G
Sbjct: 380 ALARTSG 386


gb|AAP47137.1| citrate synthase [Rickettsia sp. Chad]
(384 aa)

Score: 83 bits (204), Expect: 1.44281e-14
Length: 404, Idn/Pos/Gap = 96/176/63 (23%/43%/15%)

Query:  60 VRERFGEEVLDACTVNQAYG------GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQR 112
           ++   GE+V+D   V+          G  S  +     + +D  +GI R RG+ I     
Sbjct:  19 LKASIGEDVIDISRVSAEADCFTYDPGFMSTASCQSTITYIDGDKGILRHRGYDI-----  73

Query: 113 LLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHER 172
                K   E+     + +LL+ GE+P+  Q  +  + +   + V            +ER
Sbjct:  74 -----KDLAEKSDFLEVAYLLIYGELPSGEQYNNFTKQVAHHSLV------------NER 116

Query: 173 MHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLE--------DALTLIARLPAVA 224
           +H + Q     +       MA   A     S F+   L          A+ +IA++P +A
Sbjct: 117 LHYLFQ-----TFCSSSHPMAIMLAAVGSLSAFYPDLLNFKEADYELTAIRMIAKIPTIA 171

Query: 225 ARIYRNTFHGGKHVPAEKIEKVDD-MGMRLARS-LGFELNEF--DELMRLYLVLHADHEG 280
           A  Y+ +       P   ++  ++ + M  A     + +N    + L +++ +LHADHE 
Sbjct: 172 AMSYKYSIGQPFIYPDNSLDFTENFLHMMFATPCTKYTVNPIIKNALNKIF-ILHADHEQ 230

Query: 281 GNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTE 340
            N S   VR+ GS+ ++P+   + G+  L GP HG AN+ V+     M +++G+     +
Sbjct: 231 -NASTSTVRIAGSSGANPFACISTGIASLWGPAHGGANEAVI----NMLKEIGSSEYIPK 285

Query: 341 NLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREF------ALKHLPHDEMFQLVSKL 394
            + +   +   +   + GFGH V +  DPR    +E       AL  L ++ + Q+  +L
Sbjct: 286 YIAKA--KDKNDPFRLMGFGHRVYKNYDPRAAVLKETCKEVLKALGQLDNNPLLQIAIEL 343

Query: 395 YEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLF 438
             +  +  +E    +  +PNVD +SGI+ +  G + S  +TVL 
Sbjct: 344 EAIALK--DEYFVERKLYPNVDFYSGIIYKAMG-IPSQMFTVLL 384


ref|NP_394280.1| probable citrate (si)-synthase [Thermoplasma acidophilum DSM 1728]
emb|CAC11948.1| probable citrate (si)-synthase [Thermoplasma acidophilum]
(391 aa)

Score: 83 bits (204), Expect: 1.47938e-14
Length: 332, Idn/Pos/Gap = 97/146/41 (29%/43%/12%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +L L GE+P    +E     +++   +P  V  ++ ELP E        S AV++     
Sbjct:  53 YLFLYGELPNRLDLELFQSKVQKGYELPDFVKDIIFELPRE--------SDAVAM-----  99

Query: 191 KMAEAYAQGAPKSTF-WEYCLE--DALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVD 247
           +MA   A       F W   L+   A   I  + AV A +YR+    G   P + +E  D
Sbjct: 100 QMAAFSALATSTYNFKWNADLDRDQAAKAIGLMSAVTANVYRHIMGKG---PVD-LEPSD 155

Query: 248 DMGMRLARSLGFELNEFDEL--MRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAG 305
                  RS        DE+  M   L+L+ DHE    S  A  +  S LSD Y   AA 
Sbjct: 156 SFAESFLRSTLDRTPSEDEIDAMNAALILYTDHEV-PASTTAGLVAVSTLSDMYSGIAAA 214

Query: 306 LNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHV-IPGFGHAVL 364
           L  L GPLHG A +     ++Q +E +G+     +N+     + +  G+  + GFGH V 
Sbjct: 215 LAALKGPLHGGAAEAS---IMQFQE-IGD----PDNVDAWFRDNIVNGNKRLMGFGHRVY 266

Query: 365 RRTDPRYTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQG----KVKNPWPNVDQHSG 420
           +  DPR    R +A K   +D       K++++  R LE+ G      K  +PN D  SG
Sbjct: 267 KTYDPRARIFRRYAEKLSANDPE---AKKMFDIATR-LEKIGIDTFGSKKIYPNTDYFSG 322

Query: 421 ILLRYYGL-VESNFYTVLFGVSRALGTLSSLV 451
           I+    G  + +N YT  F +SR  G +S  +
Sbjct: 323 IVYLALGYPLRNNIYTSFFALSRVTGWISHFM 354


ref|YP_095559.1| 2-methylcitrate synthase [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
gb|AAU27612.1| 2-methylcitrate synthase [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
(372 aa)

Score: 83 bits (204), Expect: 1.64887e-14
Length: 372, Idn/Pos/Gap = 94/167/46 (25%/44%/12%)

Query:  98 EGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAV 157
           +G+ +RG+SI +            E    E + +LL  GE+PT+ +++   + L     +
Sbjct:  26 KGLNYRGYSINDL----------AEYASFEEVAYLLHYGELPTQKELDVYIKKLVNLRHI  75

Query: 158 PPEVLRLLDELPHERMHPMTQFSVAVSLL---QHESKMAEAYAQGAPKSTFWEYCLEDAL 214
           P +VL+ + +L  +  HPM     A S L   + E    + Y              E A 
Sbjct:  76 P-DVLKTVLKLIPKNTHPMDVLRTACSFLGTIEPEENFKQQY--------------EIAD 120

Query: 215 TLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFD-ELMRLYLV 273
            L+A  P +    Y  T+H      +   E+    G  LA   G + ++ + ++M + L+
Sbjct: 121 RLLALFPGIMCYWY--TYHFKNKEISGLSEEDTTGGHFLALLHGRKPSKIETDMMNVSLI 178

Query: 274 LHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLG 333
           L+A+HE  N S  A R+  + L+D Y +  + +  L GPLHG AN+  +  + + K    
Sbjct: 179 LYAEHEF-NASTFAARVTAATLADFYSAITSAIGTLRGPLHGGANEAAMGLIERFK---- 233

Query: 334 NRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSK 393
               T +       + L    +I GFGH V    DPR    ++++ +    +E   L+  
Sbjct: 234 ----TPDEAAIGIKQMLASKELIMGFGHRVYTTCDPRSDIIKKWSFRL--GEEKGNLL-- 285

Query: 394 LYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWD 453
           LY +  R+ E   + K  +PN+D +S     Y   + ++ +T +F +SR  G  S+ V++
Sbjct: 286 LYHISERIEEIMWQEKKLFPNLDFYSASAYHYCD-IPTHLFTPIFVMSRITG-WSAHVFE 343

Query: 454 RALGLPIERPKS 465
           +     + RP S
Sbjct: 344 QRANNKLIRPTS 355


gb|AAS89949.1| GltA [Bartonella phoceensis]
(338 aa)

Score: 82 bits (202), Expect: 2.44061e-14
Length: 319, Idn/Pos/Gap = 85/149/28 (26%/46%/8%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LLL GE+PT+ +     + + +   V  +  R       +  HPM   +V V+ L   S
Sbjct:  39 YLLLYGELPTKQEKNDFDRCITQHTMVHEQFARFFHGFRRDS-HPM---AVMVACLGAMS  94

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMG 250
               A+   +   T  +  +  ++ LI+++P +AA  Y+ +       P   +    +  
Sbjct:  95 ----AFYHDSIDITDPQQRMIASVRLISKVPTLAAMAYKYSIGQAFVYPRNDLSYAANF- 149

Query: 251 MRLARSLGFELNEFDEL----MRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGL 306
           +R+  S+  E  + + +    M    +LHADHE  N S   VRL GS+ ++P+   AAG+
Sbjct: 150 LRMCFSVPCEEYKINPVLVRAMDRIFILHADHEQ-NASTSTVRLAGSSGANPFACIAAGV 208

Query: 307 NGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRR 366
             L GP HG AN+  L+    M +++G+     E +     +   +   + GFGH V + 
Sbjct: 209 ACLWGPAHGGANEACLK----MLQEIGSVERIPEFIARA--KDKNDPFRLMGFGHRVYKN 262

Query: 367 TDPRYTAQREF---ALKHL--PHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGI 421
            DPR    ++     LK L    D + ++  +L ++   + +E    K  +PNVD +SGI
Sbjct: 263 YDPRAKIMQKTCHEVLKELNIQDDPLLEIAMELEKIA--LNDEYFVEKKLYPNVDFYSGI 320

Query: 422 LLRYYGLVESNFYTVLFGV 440
            L+  G   +  +TVLF +
Sbjct: 321 TLKALGF-PTEMFTVLFAL 338


gb|AAU85590.1| citrate synthase [Rickettsia marmionii]
(360 aa)

Score: 82 bits (202), Expect: 2.46106e-14
Length: 380, Idn/Pos/Gap = 91/167/57 (23%/43%/15%)

Query:  80 GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEI 138
           G  S  +     + +D  +GI R RG+ I          K   E+     + +LL+ GE+
Sbjct:  19 GFMSTASCQSTITYIDGDKGILRHRGYDI----------KDLAEKSDFLEVAYLLIYGEL  68

Query: 139 PTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQ 198
           P+  Q  +  + +   + V            +ER+H + Q     +       MA   A 
Sbjct:  69 PSGEQYNNFTKQVAHHSLV------------NERLHYLFQ-----TFCSSSHPMAIMLAA 111

Query: 199 GAPKSTFWEYCLE--------DALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDD-M 249
               S F+   L          A+ +IA++P +AA  Y+ +       P   ++  ++ +
Sbjct: 112 VGSLSAFYPDLLNFKEADYELTAIRMIAKIPTIAAMSYKYSIGQPFIYPDNALDFTENFL 171

Query: 250 GMRLARS-LGFELNEF--DELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGL 306
            M  A     + +N    + L +++ +LHADHE  N S   VR+ GS+ ++P+   + G+
Sbjct: 172 HMMFATPCTKYTVNPIIKNALNKIF-ILHADHEQ-NASTSTVRIAGSSGANPFACISTGI 229

Query: 307 NGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRR 366
             L GP HG AN+ V    + M +++G+     + + +   +   +   + GFGH V + 
Sbjct: 230 ASLWGPAHGGANEAV----INMLKEIGSSEYIPKYIAKA--KDKNDPFRLMGFGHRVYKN 283

Query: 367 TDPRYTAQREFA------LKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSG 420
            DPR    +E        L  L ++ + Q+  +L  +  +  +E    +  +PNVD +SG
Sbjct: 284 YDPRAAVLKETCKEVLKELGQLDNNPLLQIAIELEAIALK--DEYFIERKLYPNVDFYSG 341

Query: 421 ILLRYYGLVESNFYTVLFGV 440
           I+ +  G + S  +TVLF +
Sbjct: 342 IIYKAMG-IPSQMFTVLFAI 360


emb|CAH12638.1| 2-methylcitrate synthase [Legionella pneumophila str. Paris]
ref|YP_123811.1| 2-methylcitrate synthase [Legionella pneumophila str. Paris]
(372 aa)

Score: 82 bits (202), Expect: 2.50247e-14
Length: 372, Idn/Pos/Gap = 93/168/46 (25%/45%/12%)

Query:  98 EGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAV 157
           +G+ +RG+SI +            E    E + +LL  GE+PT+ ++    + L     +
Sbjct:  26 KGLNYRGYSINDL----------AEYASFEEVAYLLHYGELPTQKELNVYIKKLVNLRHM  75

Query: 158 PPEVLRLLDELPHERMHPMTQFSVAVSLL---QHESKMAEAYAQGAPKSTFWEYCLEDAL 214
           P +VL+ + +L  +  HPM     A S L   + E    + Y              E A 
Sbjct:  76 P-DVLKTVLKLIPKNTHPMDVLRTACSFLGTIEPEENFKQQY--------------EIAD 120

Query: 215 TLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFD-ELMRLYLV 273
            L+A  P +    Y  T+H      +   E+    G  LA   G + ++ + ++M + L+
Sbjct: 121 RLLALFPGIMCYWY--TYHFKNKEISGLSEEDTTGGHFLALLHGRKPSKIEADMMNVSLI 178

Query: 274 LHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLG 333
           L+A+HE  N S  A R+  + L+D Y +  + +  L GPLHG AN+      +++ E+  
Sbjct: 179 LYAEHEF-NASTFAARVTAATLADFYSAITSAIGTLRGPLHGGANEAA----MELIERFK 233

Query: 334 NRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSK 393
                   ++++    L    +I GFGH V    DPR    ++++ +    +E   L+  
Sbjct: 234 TPDEAAIGIKQM----LASKELIMGFGHRVYTTCDPRSDIIKKWSFRL--GEEKGNLL-- 285

Query: 394 LYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWD 453
           LY +  R+ E   + K  +PN+D +S     Y   + ++ +T +F +SR  G  S+ V++
Sbjct: 286 LYHISERIEEIMWQEKKLFPNLDFYSASAYHYCN-IPTHLFTPIFVMSRITG-WSAHVFE 343

Query: 454 RALGLPIERPKS 465
           +     + RP S
Sbjct: 344 QRANNKLIRPTS 355


gb|AAQ08231.1| citrate synthase [Rickettsia sp. RF2125]
(389 aa)

Score: 82 bits (202), Expect: 2.766e-14
Length: 405, Idn/Pos/Gap = 97/178/67 (23%/43%/16%)

Query:  60 VRERFGEEVLDACTVNQAYG------GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQR 112
           ++   GE+V+D   V+          G  S  +     + +D  +GI R RG+ I     
Sbjct:  25 LKASIGEDVIDISRVSSEADCFTYDPGFMSTASCQSTITYIDGDKGILRHRGYDI-----  79

Query: 113 LLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHER 172
                K   E+     + +LL+ GE+P+  Q  +  + +   + V            +ER
Sbjct:  80 -----KDLAEKSDFLEVAYLLIYGELPSIEQYNNFTKQVAHHSLV------------NER 122

Query: 173 MHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLE--------DALTLIARLPAVA 224
           +H + Q     +       MA   A     S F+   L          A+ +IA++P +A
Sbjct: 123 LHYLFQ-----TFCSSSHPMAIMLAAVGSLSAFYPDLLNFKEADYELTAIRMIAKIPTIA 177

Query: 225 ARIYRNTFHGGKHVPAEKIEKVDD-MGMRLARS-LGFELNEF--DELMRLYLVLHADHEG 280
           A  Y+ +       P   ++  ++ + M  A     +++N    + L +++ +LHADHE 
Sbjct: 178 AMSYKYSIGQPFIYPDNSLDFTENFLHMMFATPCTKYKVNPIIKNALNKIF-ILHADHEQ 236

Query: 281 GNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTE 340
            N S   VR+ GS+ ++P+   + G+  L GP HG AN+ V    + M +++G    ++E
Sbjct: 237 -NASTSTVRIAGSSGANPFACVSTGIASLWGPAHGGANEAV----INMLKEIG----SSE 287

Query: 341 NLRELCWETLREGHV--IPGFGHAVLRRTDPRYTAQREFA------LKHLPHDEMFQLVS 392
           N+ +   +   +     + GFGH V +  DPR    +E        L  L ++ + Q+  
Sbjct: 288 NIPKYIAKAKDKNDPFRLMGFGHRVYKNYDPRAAVLKETCKEVLKELGQLENNPLLQIAI 347

Query: 393 KLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVL 437
           +L  +  +  +E    +  +PNVD +SGI+ +  G + S  +TVL
Sbjct: 348 ELEAIALK--DEYFIERKLYPNVDFYSGIIYKAMG-IPSQMFTVL 389


gb|AAL01663.1| citrate synthase [Ehrlichia sp. Yamaguchi]
(409 aa)

Score: 82 bits (201), Expect: 3.61251e-14
Length: 404, Idn/Pos/Gap = 104/182/64 (25%/45%/15%)

Query:  65 GEEVLDACTVNQAYG------GMRSLKAMVYETSLLDPQEGIR-FRGFSIPECQRLLPRA 117
           G++ +D  ++ +  G      G  S  A   + + +D  +GI  +RG +I +   L+ + 
Sbjct:  24 GDKAVDITSLYKNTGILTYDPGFMSTAACESKITFIDGNKGILCYRGHNIVD---LVNKN  80

Query: 118 KPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMT 177
           K   E      +++LL  G  P+   +++    + +   +PP+V+  + +   +  HPM+
Sbjct:  81 KSFVE------IIYLLFYGVFPSAEDLQNFTLQISQEY-MPPQVVYDVIKSFSQDSHPMS 133

Query: 178 QFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKH 237
                 S L      +  + Q A K       L+ A   +A++ ++ A IYR       +
Sbjct: 134 ILMACFSALA-----SYYHDQEADKDE-----LKYAKLAVAKIASMVALIYR-------Y 176

Query: 238 VPAEKIEKVDDMGMRLARSLGFELNEFD-----------ELMRLYLVLHADHEGGNVSAH 286
           +  +     D    +L+ S  F    FD           + + +  +LHADHE  N S  
Sbjct: 177 ITNQDFITAD---TKLSYSKNFVHMMFDISSYKFTQVVAKALDIIFILHADHEQ-NASTA 232

Query: 287 AVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELC 346
            VRL GS+ +D +    AG   L GP HG AN+ V+  L+ + EK  N     + +++  
Sbjct: 233 TVRLAGSSGADLFACLVAGTATLWGPAHGGANEAVINMLMTI-EKPSNVKQFIQKVKDGS 291

Query: 347 WETLREGHVIPGFGHAVLRRTDPRYTAQ----REFALKHLPHDEMFQLVSKLYEVVPRVL 402
            +T R    + GFGH V +  DPR        RE  L  L  D+    V++  E +   L
Sbjct: 292 -KTTR----LMGFGHRVYKNYDPRAKIMCKICRE-VLNDLGIDDPLLEVAQELENI--AL 343

Query: 403 EEQGKV-KNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALG 445
           ++   + +N +PNVD +SGI+L+  G +    +T LF ++R  G
Sbjct: 344 QDSYFIERNLYPNVDFYSGIILKAIG-IPVRMFTTLFALARTTG 386


gb|AAV47314.1| citrate synthase II [Haloarcula marismortui ATCC 43049]
ref|YP_137020.1| citrate synthase II [Haloarcula marismortui ATCC 43049]
(381 aa)

Score: 82 bits (201), Expect: 3.70408e-14
Length: 371, Idn/Pos/Gap = 99/157/39 (26%/42%/10%)

Query:  80 GMRSLKAMVYETSLLDPQEG-IRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEI 138
           G+  +     E S++D   G + +RG++I +       AK +      E +L+LL  G +
Sbjct:   8 GLEGVIVAESELSVIDGDAGKLVYRGYTIEDL------AKGASY----EEVLYLLWHGHL  57

Query: 139 PTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQ 198
           P   ++    Q +     V  +V+  + +L     +PM     AVS+L   S    A   
Sbjct:  58 PNRDELSEFKQAMVDARGVDDDVISTVRQLAEADENPMAALRTAVSML---SAFDPAPED 114

Query: 199 GAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLG 258
             P        LE    + A++P + A   R     GK  P E  + +D     L    G
Sbjct: 115 AEPTDEMVN--LETGRRITAKIPTIIAAFTR--IRDGKE-PVEPHDDLDHAANFLYMLNG 169

Query: 259 FELNE-FDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLA 317
            E ++   ++    LVLHADH G N S  +     S LSD + +  + +  L GPLHG A
Sbjct: 170 EEPDDVLADVFDQALVLHADH-GLNASTFSAITTASTLSDVHSAVTSAIGTLKGPLHGGA 228

Query: 318 NQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREF 377
           NQ+V+  L ++ +   +     +N        L EG  + GFGH V    DPR     E 
Sbjct: 229 NQDVMEMLKEVDDAESDPLDWVKN-------ALDEGRRVSGFGHRVYNVKDPRAKILGER 281

Query: 378 ALKHLPHDEMFQLVSKL--YEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGL-VESNFY 434
           +       E+ +    L  YE+   + +   + K   PNVD +S     YY + +  + Y
Sbjct: 282 S------KELGEAAGTLKWYEMSTTIEDYLMEEKGLAPNVDFYSAS--TYYQMGIPIDIY 333

Query: 435 TVLFGVSRALG 445
           T +F +SR  G
Sbjct: 334 TPIFAMSRVGG 344


ref|NP_978686.1| citrate synthase MmgD [Bacillus cereus ATCC 10987]
gb|AAS41294.1| citrate synthase MmgD [Bacillus cereus ATCC 10987]
(372 aa)

Score: 81 bits (200), Expect: 4.71809e-14
Length: 327, Idn/Pos/Gap = 90/147/30 (27%/44%/9%)

Query: 132 LLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESK 191
           LLL   +P E +   + + LK   AVP  V  +L  LP E  HPM      VS L     
Sbjct:  53 LLLEEHLPNEDEKAKLEKKLKEEYAVPEGVFNVLKALPKE-THPMDGLRTGVSALAGYDN 111

Query: 192 MAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFH-GGKHVPAEKIEKVDDMG 250
             E  +    KS  ++        L++++P + A    N++H      P E ++++    
Sbjct: 112 DIENRSLEVNKSRGYK--------LLSKVPNIVA----NSYHILNNEEPIEPLKELSYSA 159

Query: 251 MRLARSLGFELNEFDE-LMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGL 309
                  G +  E +E +    LVL+++HE  N S    R++ S  SD Y +    +  L
Sbjct: 160 NFFYMLTGKKPTELEEKIFDRSLVLYSEHEMPN-STFTARVIASTQSDLYGALTGAVASL 218

Query: 310 AGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAV-LRRTD 368
            G LHG AN+ V+  LL+     GN     E   EL  + L     I GFGH V +++ D
Sbjct: 219 KGSLHGGANEAVMYMLLEA----GN----VEKFEELLQKKLYNKEKIMGFGHRVYMKKMD 270

Query: 369 PRYTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGL 428
           PR    +E ALK L   +    + ++ E   +++E++   K  +PN+D ++  +    G 
Sbjct: 271 PRALMMKE-ALKQLCDVKGDYTLYEMCEAGEKIMEKE---KGIYPNLDYYAAPVYWMLG- 325

Query: 429 VESNFYTVLFGVSRALGTLSSLVWDRA 455
           +    YT +F  SR +G  + ++   A
Sbjct: 326 IPIQLYTPIFFSSRTVGLCAHVIEQHA 352


ref|NP_245213.1| GltA [Pasteurella multocida subsp. multocida str. Pm70]
gb|AAK02360.1| GltA [Pasteurella multocida subsp. multocida str. Pm70]
(428 aa)

Score: 81 bits (199), Expect: 5.62164e-14
Length: 361, Idn/Pos/Gap = 90/156/42 (24%/43%/11%)

Query: 132 LLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMT---QFSVAVSLLQH 188
           LLL GE P+  + ++  Q ++R   V  ++ R       +  HPM      S A++   H
Sbjct:  89 LLLFGERPSPEEYKNFTQLVRRHTLVHEQISRFFHGFRRDS-HPMAIMCGVSGALAAFYH 147

Query: 189 ESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDD 248
           +S                      A+ L+A++P +AA  Y+ +       P   +    +
Sbjct: 148 DSLDINDITHREIT----------AIRLLAKMPTLAAMCYKYSIGQPFMFPQNHLSYSGN 197

Query: 249 -MGMRLARSLG-FELNE-FDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAG 305
            + M  A     + +N   +  M    +LHADHE  N S   VR   S+ ++P+   AAG
Sbjct: 198 FLYMMFATPCEPYIVNPVLERAMDRIFILHADHEQ-NASTSTVRTAASSGANPFACIAAG 256

Query: 306 LNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLR 365
           +  L GP HG AN+      + M E++G      E +     +   +   + GFGH V +
Sbjct: 257 IASLWGPAHGGANEAC----INMLEEIGTVDRIPEFIARA--KDKNDPFRLMGFGHRVYK 310

Query: 366 RTDPRYTAQREF---ALKHLP-HDEMFQLVSKLYEVV---PRVLEEQGKVKNPWPNVDQH 418
             DPR    R+     LK L   + +F +  +L  +    P  ++ +      +PNVD +
Sbjct: 311 NYDPRAKVMRQTCHEVLKELNIQNPLFDVAMELERIALSDPYFIDHK-----LYPNVDFY 365

Query: 419 SGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRAL---GLPIERPKSVTTQWIREHF 475
           SGI+L+  G + ++ +TV+F ++R +G ++   W        + I RP+ +        F
Sbjct: 366 SGIILKAIG-IPTSMFTVMFALARTVGWIAH--WKEMFKPGNMKIVRPRQLYMGEKERSF 422

Query: 476 E 476
           E
Sbjct: 423 E 423


emb|CAG35123.1| probable citrate synthase [Desulfotalea psychrophila LSv54]
ref|YP_064130.1| citrate synthase [Desulfotalea psychrophila LSv54]
(428 aa)

Score: 81 bits (199), Expect: 6.37114e-14
Length: 454, Idn/Pos/Gap = 110/185/59 (24%/40%/12%)

Query:  32 RALSTSSATSLQEAVRSKIEPMRA-QVHEVRERFGEEVLDACTVNQAYGGMRSLKAMVYE  90
           +A  T    S +  V S  E  R   +  +R + G   +D         G  S  A   +
Sbjct:   4 KATLTVGGASYELDVTSGTEDERCIDIQSLRAKSGYITMDP--------GFGSTGACFSD  55

Query:  91 TSLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQ 149
            + +D + GI R+RG+ I +        +             L++ GE+P    +    +
Sbjct:  56 ITYVDGERGILRYRGYPIEQIAERASFVETCS----------LIIYGELPDAETLNRFRR 105

Query: 150 DLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQ-HESKMAEAYAQGAPKSTFWEY 208
            L   A +   +       P E   PM   S  ++L+      + E +++G         
Sbjct: 106 ALAEHAPLHTSLYHYFSGFP-ESSPPMAILSAMLNLVSCFHPGVLEVHSEGHGFD----- 159

Query: 209 CLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFE----LNEF 264
               A  L++++  +AA  YR +     + P   +    +  + +  S  F+        
Sbjct: 160 --RTAALLLSKVRTIAAWSYRMSVGKPFNQPNPHLTYCANF-LHMMFSEPFQEYIPSPAV 216

Query: 265 DELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRW 324
           +  + L+L+LHADHE  N S   VR V S+ ++ + S A+G+  L GPLHG AN  V+  
Sbjct: 217 ERALALFLILHADHEQ-NCSTSTVRTVASSRANLFSSVASGVCALWGPLHGGANAAVIEM 275

Query: 325 LLQMK------EKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFA 378
           L ++       +   NR     N  +L            GFGH V +  DPR +  ++  
Sbjct: 276 LEEIMASGRKIDYYINRAKDKSNDYKLM-----------GFGHRVYKNFDPRASILKKRV 324

Query: 379 LKHLPH----DEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFY 434
            + L      D +  +  +L E   +  +E    +  +PNVD +SGILLR  G +    Y
Sbjct: 325 YEVLAELHKSDPLLDIALELEEKTLK--DEYFISRKLYPNVDFYSGILLRAIG-IPPEMY 381

Query: 435 TVLFGVSRALGTLSSLVWDRALGLPIERPKSVTT 468
           TV+F + R  G +++        L I RP+ V T
Sbjct: 382 TVMFAIGRMPGWIANWRELHDQNLRITRPRQVYT 415


ref|NP_930369.1| hypothetical protein plu3138 [Photorhabdus luminescens subsp. laumondii TTO1]
emb|CAE15512.1| unnamed protein product [Photorhabdus luminescens subsp. laumondii TTO1]
(403 aa)

Score: 81 bits (199), Expect: 6.58737e-14
Length: 220, Idn/Pos/Gap = 62/105/18 (28%/47%/8%)

Query: 253 LARSLGFELNEF-DELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAG 311
           LA   G + ++  +E++  +L+LHA+H G N S   VR V S+ +DP+ + AAG+   +G
Sbjct: 194 LATCFGQQCDDVAEEMLNKFLILHAEH-GLNCSTATVRAVASSGADPFNAVAAGICAFSG 252

Query: 312 PLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRY 371
           PLHG A+  V   +  + +        ++N+     E +     + GFGH + ++ DPR 
Sbjct: 253 PLHGGASGAVGLMIDDIHD-------NSKNISTFIDELVERKQRLMGFGHRIYKQPDPRA 305

Query: 372 TAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGK-----VKNPWPNVDQHSGILLRYY 426
           +   +  +K       F ++S    +   +  E  K      +  +PN D  +G+LLR  
Sbjct: 306 SYMSDILIK---QKAKFDVISSYVNISQELASEVSKRPYFSQRGLYPNPDLFNGLLLRRA 362

Query: 427 GLVESNFYTVLFGVSRALGTLSSLVWDRALGLPIERPKSV 466
           G  +S+  T L   SRA G L+          PI RP+ +
Sbjct: 363 GF-KSHMNTALLCFSRAAGWLAHYYDSIDSKAPILRPQEL 401


ref|YP_023667.1| citrate synthase [Picrophilus torridus DSM 9790]
gb|AAT43474.1| citrate synthase [Picrophilus torridus DSM 9790]
(373 aa)

Score: 81 bits (199), Expect: 6.75434e-14
Length: 370, Idn/Pos/Gap = 93/159/52 (25%/42%/14%)

Query:  91 TSL--LDPQEG-IRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESV 147
           TSL  +D ++G +R+RG+ I          K   E    E + +L+  GE+P   ++E  
Sbjct:  15 TSLTSIDGEKGELRYRGYDI----------KDLVEHCSFEEVAYLMFYGELPKRDELEHF  64

Query: 148 CQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWE 207
             ++ +   +P  V  ++  +P +          A+++      M  A+A  + +   WE
Sbjct:  65 KSNVMKNYKIPENVKNIIKNMPRD--------GDALAI------MEAAFAALSTEEYTWE 110

Query: 208 --YCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFD 265
                E A  ++ R   + + ++R  +  G+ +   + +   +  +      G + ++  
Sbjct: 111 KERDREKAAEIMGRALGIVSAVFR--YRDGREIKDPENKGYAEAFLNACFDSGIDEDKI- 167

Query: 266 ELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWL 325
           + M   L+L+ DHE    S  A  +  S LSD Y    A +  L GPLHG A +   +  
Sbjct: 168 KAMNAALILYIDHEV-PASTTAALVASSTLSDMYSCVTAAIAALKGPLHGGAAEAAYKQF 226

Query: 326 LQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHD 385
           L +K          EN+       L     + GFGH V +  DPR    +E A K+   D
Sbjct: 227 LAIKSPENVDSWFNENI-------LNNKKRLMGFGHRVYKTYDPRMLIFKELARKNAKTD 279

Query: 386 EMFQLVSKLYEVVPRVLEEQGKVKN-----PWPNVDQHSGILLRYYGLVESNFYTVLFGV 440
           E      K+ E+  R LE  G VKN      +PN D +SGI+    G      +T LF +
Sbjct: 280 EQ----KKILELAER-LEALG-VKNFGQKKIFPNTDYYSGIVFNEIGF-PLYMFTTLFAL 332

Query: 441 SRALGTLSSL 450
           SR +G ++ +
Sbjct: 333 SRVVGWVAHI 342


ref|NP_636407.1| citrate synthase 2 [Xanthomonas campestris pv. campestris str. ATCC 33913]
gb|AAM40331.1| citrate synthase 2 [Xanthomonas campestris pv. campestris str. ATCC 33913]
(384 aa)

Score: 80 bits (198), Expect: 7.10109e-14
Length: 344, Idn/Pos/Gap = 91/146/29 (26%/42%/8%)

Query: 127 EGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLL 186
           E + +LL+ G++P   ++      L+    VP  V   L++LP    HPM      VS+L
Sbjct:  54 EEIAYLLVHGKLPNSGELRGYKAKLRSLRGVPAAVKTALEQLP-PSAHPMDVMRTGVSVL 112

Query: 187 QHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKV 246
                  + +     +          A  L+A L ++    Y  + H GK +  E  +  
Sbjct: 113 GCLQPEKDDHNHPGARDI--------ADKLMASLGSMLLYWYHYS-HNGKRIEVETDD-- 161

Query: 247 DDMGMRLARSL-GFELNE-FDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAA 304
           D +G      L GF   E +   M   L+L+A+HE  N S  A R++    SD Y + A 
Sbjct: 162 DSIGGHFLHLLHGFAPKESWVRAMHTSLILYAEHEF-NASTFASRVIAGTGSDMYSAIAG 220

Query: 305 GLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVL 364
           G+  L GP HG AN+           ++  R  T +         +    V+ GFGH V 
Sbjct: 221 GIGALRGPKHGGANEVAF--------EVQKRYDTPDEAEADIKARVERKEVVIGFGHPVY 272

Query: 365 RRTDPRYTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLR 424
             +DPR    ++ A +    DE  Q   K+Y++  R+      +K  +PN+D  S +   
Sbjct: 273 TVSDPRNKVIKDVAREL--SDE--QGSRKMYDIAERLETVMWDIKKMFPNLDWFSAVSYH 328

Query: 425 YYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLPIERPKSVTT 468
             G V +  +T LF ++R  G  + ++  R  G  I RP +  T
Sbjct: 329 MMG-VPTAMFTPLFVLARTAGWSAHIIEQRVDG-KIIRPSANYT 370


ref|NP_633551.1| Citrate synthase [Methanosarcina mazei Go1]
gb|AAM31223.1| Citrate synthase [Methanosarcina mazei Goe1]
(355 aa)

Score: 80 bits (198), Expect: 7.52818e-14
Length: 348, Idn/Pos/Gap = 91/161/35 (26%/46%/10%)

Query: 125 LP-EGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAV 183
           LP + + +LL+ GE+  E ++      L     +  EV+ ++  + +  +  M      V
Sbjct:  28 LPYDAVSYLLIKGELSEEKELAEYSARLHAERGINREVMDVI-RMCNLNIDSMEALLTVV  86

Query: 184 SLL-QHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEK 242
           S + Q +  + +   +G          +  A+ LIA +P + A  YR T +G + VP + 
Sbjct:  87 SFISQFDPDLYDNSLEGN---------MRKAIRLIAVVPTIVAAYYR-TANGKEPVPPDP 136

Query: 243 IEKVDDMGMRLARSLGFELNEFD-ELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLS 301
              +      L    G + +  + E+M    +L A+HE  N S  + R+  S +SD Y +
Sbjct: 137 --SLAHGANFLYMIKGSKPDPLEAEVMEKDFILSAEHEL-NASTFSSRVTASTMSDLYSA 193

Query: 302 FAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGH 361
             +GL  L GPLHG A  EV    + M E +G    + EN  +   E + +   I GFGH
Sbjct: 194 VVSGLCTLKGPLHGGARSEV----MTMIETIG----SPENAEKFVLEKIEKREKIMGFGH 245

Query: 362 AVLRRTDPRYTAQREFA--LKHLPHDEMFQLVSKLYE--VVPRVLEEQGKVKNP-WPNVD 416
            V +  DPR T  ++ +  L     D  +   ++  E  V+  ++E++GK   P +PN+D
Sbjct: 246 RVYKTYDPRGTIFKQLSRRLAEAKGDMHWYETAEAIENAVIRELVEKRGK---PIYPNID 302

Query: 417 QHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLPIERPK 464
            +SG++ +Y   +     T +F + R  G ++   +D+     I RP+
Sbjct: 303 FYSGVIYKYME-IPPQLATSIFAIGRISGWIAH-CFDQYEKKKIIRPR 348


gb|AAL01660.1| citrate synthase [Ehrlichia chaffeensis]
(433 aa)

Score: 80 bits (198), Expect: 7.78368e-14
Length: 337, Idn/Pos/Gap = 86/148/56 (25%/43%/16%)

Query: 129 LLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQ----FSVAVS 184
           +++LL  G +P    +++    + +    P  V  ++   P +  HPM+     FS   S
Sbjct: 103 IVYLLFYGVLPGLEDLQNFISQISQEYNPPKIVHDVIKSFPRDS-HPMSILMACFSALAS 161

Query: 185 LLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIE 244
              ++   A+               L+ A   +A++ ++ A IYR       ++  +   
Sbjct: 162 CYHNQDNSADQ--------------LKCAKLAVAKVASIIALIYR-------YITNQDFV 200

Query: 245 KVDDMGMRLARSLGFELNEFD-----------ELMRLYLVLHADHEGGNVSAHAVRLVGS 293
           + D    +L+ S  F    FD           + + +  VLHADHE  N S   VRL GS
Sbjct: 201 ESD---TKLSYSENFVHMMFDISSYKFTQVVAKALDIIFVLHADHEQ-NASTATVRLSGS 256

Query: 294 ALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREG 353
           + +D +    AG   L GP HG AN+ V+  L+ + EK  N     + +++    T    
Sbjct: 257 SGADLFACLVAGTATLWGPAHGGANEAVINMLMAI-EKPSNVKQFIQKVKDGNKSTR--- 312

Query: 354 HVIPGFGHAVLRRTDPR----YTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKV- 408
             + GFGH V +  DPR    Y   RE       +D + ++  +L  +    L++   + 
Sbjct: 313 --LMGFGHRVYKNYDPRAKIMYKICREVLNNLNVNDPLLEIALELENI---ALQDSYFID 367

Query: 409 KNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALG 445
           +N +PNVD +SGI+L+  G +    +T LF ++R  G
Sbjct: 368 RNLYPNVDFYSGIVLKAIG-IPVRMFTTLFALARTSG 403


gb|AAT70226.1| citrate synthase [Ehrlichia canis]
gb|AAL01661.1| citrate synthase [Ehrlichia canis]
gb|AAT37164.1| citrate synthase [Ehrlichia canis]
ref|ZP_00211186.1| COG0372: Citrate synthase [Ehrlichia canis str. Jake]
(416 aa)

Score: 80 bits (198), Expect: 8.11527e-14
Length: 394, Idn/Pos/Gap = 95/176/44 (24%/44%/11%)

Query:  65 GEEVLDACTVNQAYG------GMRSLKAMVYETSLLDPQEGIR-FRGFSIPECQRLLPRA 117
           G +V+D  ++ +  G      G  S  A   + + +D  +GI  +RG++I +   L+   
Sbjct:  24 GNKVIDITSLYKGTGILTYDPGFMSTAACESKITFIDGNKGILCYRGYNIAD---LVNNN  80

Query: 118 KPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMT 177
           K   E      +++LL  G  P+   ++     + +   +PPE++  + +   +  HPMT
Sbjct:  81 KSFIE------IVYLLFYGSFPSVDNLKDFMLQISQEY-MPPEMVCDVIKSFSQDSHPMT 133

Query: 178 QFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKH 237
                 S L      +  + Q   K       L+     +A++ ++ A IYR T +    
Sbjct: 134 ILMACFSALA-----SYYHDQAVDKDG-----LKHPKLAVAKVASIIAMIYRYTTNQDFI 183

Query: 238 VPAEKIEKVDDMGMRLARSLGFELNEF-DELMRLYLVLHADHEGGNVSAHAVRLVGSALS 296
            P   +   ++    +     ++  +   + + +   LHADHE  N S   VRL GS+ +
Sbjct: 184 EPNHGLSYSENFIHMMFDISSYKFTQVVAKALDVIFTLHADHEQ-NASTATVRLAGSSGA 242

Query: 297 DPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVI 356
           D +    AG+  L GP HG AN+ V+  L+ + EK  N     + +++    T      +
Sbjct: 243 DLFACLVAGIATLWGPAHGGANEAVINMLMAI-EKPSNVKQFIQKVKDGNKSTR-----L 296

Query: 357 PGFGHAVLRRTDPRYTAQREFALKHLP----HDEMFQLVSKLYEVVPRVLEEQGKV-KNP 411
            GFGH V +  DPR     E   + L     +D + ++  +L  +    L++   + ++ 
Sbjct: 297 MGFGHRVYKNYDPRAKIICEICKEVLNDLGVNDPLLEIALELENI---ALQDSYFIERSL 353

Query: 412 WPNVDQHSGILLRYYGLVESNFYTVLFGVSRALG 445
           +PNVD +SGI+L+  G +    +T LF ++R  G
Sbjct: 354 YPNVDFYSGIILKAIG-IPVRMFTTLFALARTSG 386


ref|ZP_00265711.1| COG0372: Citrate synthase [Pseudomonas fluorescens PfO-1]
(375 aa)

Score: 80 bits (198), Expect: 8.53188e-14
Length: 333, Idn/Pos/Gap = 88/147/35 (26%/44%/10%)

Query: 127 EGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLL 186
           E + +LLL GE+PT++Q+      L +   +P  +  +L+ +P +  HPM       S L
Sbjct:  49 EEVAYLLLYGELPTKAQLADYQGKLSKLRDLPQALKEVLERIPAD-AHPMDVMRTGCSFL 107

Query: 187 QHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKV 246
                         P+  F E   +    L+A  PA+    YR + H GK +     E  
Sbjct: 108 ----------GNIEPEKDFSEQ-RDKTDRLLAAFPAIMCYWYRFS-HDGKRINCVSDEP- 154

Query: 247 DDMGMRLARSLG----FELNEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSF 302
             +G      L      EL+   ++M + L+L+A+HE  N S    R+  S LSD Y   
Sbjct: 155 -SIGGHFLHLLHDKKPSELHV--KVMNVSLILYAEHEF-NASTFTARVCASTLSDLYSCV 210

Query: 303 AAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHA 362
            A +  L GPLHG AN+      ++M E+      + E   +     L     I GFGHA
Sbjct: 211 TAAIGSLRGPLHGGANEAA----MEMIERFS----SPEEAVKGTLGMLERKDKIMGFGHA 262

Query: 363 VLRRTDPRYTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGIL 422
           + + +DPR    + ++ K L  +   +++  + E + + + EQ K+   +PN D +    
Sbjct: 263 IYKDSDPRNEVIKGWS-KKLADEVGDKVLFAVSEAIDKTMWEQKKL---FPNADFYHASA 318

Query: 423 LRYYGLVESNFYTVLFGVSRALGTLSSLVWDRA 455
             + G + +  +T +F  SR  G  + +   RA
Sbjct: 319 YHFMG-IPTKLFTPIFVCSRLTGWAAHVFEQRA 350


ref|NP_615222.1| citrate (si)-synthase [Methanosarcina acetivorans C2A]
gb|AAM03702.1| citrate (si)-synthase [Methanosarcina acetivorans str. C2A]
(355 aa)

Score: 80 bits (197), Expect: 9.91449e-14
Length: 345, Idn/Pos/Gap = 85/157/32 (24%/45%/9%)

Query: 127 EGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLL 186
           + + +LL+ G +P E ++      L     +  EV+ ++  + +  +  M      +S +
Sbjct:  31 DAVSYLLIRGRLPGEQELAEYSARLHAERRINKEVIDVI-RMCNFNIDAMAALRTVISFI  89

Query: 187 -QHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEK 245
            Q +  + ++  +G          +  A+ LIA +P + A  YR   +G + +P +    
Sbjct:  90 SQFDPDLNDSSPEGN---------MRKAIRLIAIVPTIVATYYRMA-NGKEPLPPDP--S 137

Query: 246 VDDMGMRLARSLGFELNEFD-ELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAA 304
           +      L    G + +  D E+M    +L A+HE  N S  + R+  S +SD Y +  +
Sbjct: 138 LSHGANFLYMIKGSKPDPLDAEVMEKDFILSAEHEL-NASTFSSRVTASTMSDLYSAVVS 196

Query: 305 GLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVL 364
           GL  L GPLHG A  EV+  L ++         + EN  +   E + +   I GFGH V 
Sbjct: 197 GLCTLKGPLHGGARAEVMTMLDEVA--------SPENAEKFVLEKISQREKIMGFGHRVY 248

Query: 365 RRTDPRYTAQREFA--LKHLPHDEMFQLVSKLYE--VVPRVLEEQGKVKNPWPNVDQHSG 420
           +  DPR    ++ +  L     D  +   ++  E  VV  ++E++G  K  +PNVD +SG
Sbjct: 249 KTYDPRGVIFKQLSKKLAESKGDMHWYTTAEAVENVVVRELVEKRG--KPIYPNVDFYSG 306

Query: 421 ILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLPIERPKS 465
           ++ +Y   +     T +F + R  G ++   +D+     I RP++
Sbjct: 307 VIYKYME-IPPQLATSIFAIGRVSGWIAH-CFDQYERKKIIRPRA 349


gb|AAF94495.1| methylcitrate synthase [Vibrio cholerae O1 biovar eltor str. N16961]
ref|NP_230981.1| methylcitrate synthase [Vibrio cholerae O1 biovar eltor str. N16961]
pir||A82213 methylcitrate synthase VC1337 [imported] - Vibrio cholerae  (strain N16961 serogroup O1)
(377 aa)

Score: 80 bits (197), Expect: 1.1715e-13
Length: 330, Idn/Pos/Gap = 91/144/38 (27%/43%/11%)

Query: 132 LLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESK 191
           LLL G +PT+++++     L     +P ++ + L+ +P E  HPM       S+L +   
Sbjct:  54 LLLVGYLPTQAELDQYKTRLIGLRGLPEKLKQALELIPAE-AHPMDVMRTGCSILGNLE- 111

Query: 192 MAEAYAQGAPKSTFWEYCLEDALT--LIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDM 249
                    P+ TF E   + A T  ++A  PA+    YR +  G +   A++ E  D +
Sbjct: 112 ---------PEHTFAE---QQAATERMLALFPAIICYWYRFSHEGVRIDTADQSE--DSI 157

Query: 250 GMRLARSL-GFELNE-FDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLN 307
           G    + L G   +E F ++M   L L+A+HE  N S  A R+  S LSD +      + 
Sbjct: 158 GGYFLKMLTGQAPSELFKKVMHCSLTLYAEHEF-NASTFAARVCASTLSDIHSCVTGAIG 216

Query: 308 GLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRT 367
            L GPLHG AN+  +  + Q          + +         L     I GFGHA+ R +
Sbjct: 217 TLRGPLHGGANEAAMAMIEQWH--------SADEAEAGIMRMLASKEKIMGFGHAIYRES 268

Query: 368 DPRYTAQREF--ALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRY 425
           DPR    +E+  AL     D      S LY V  RV     + K+ + N D        +
Sbjct: 269 DPRNALIKEWSKALSEAVGD------SHLYAVSERVEAVMKREKDLFCNADFFHASAYHF 322

Query: 426 YGLVESNFYTVLFGVSRALGTLSSLVWDRA 455
            G + +  +T +F +SR  G  + +   RA
Sbjct: 323 MG-IPTKLFTPIFVMSRLTGWAAHVYEQRA 351


emb|CAD92107.1| citrate synthase [Bartonella schoenbuchensis]
(337 aa)

Score: 80 bits (196), Expect: 1.35004e-13
Length: 331, Idn/Pos/Gap = 92/147/56 (27%/44%/16%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LLL GE+PT+ + +   + +     V  +  R       +  HPM   +V V+ L   S
Sbjct:  40 YLLLYGELPTKQEKDDFDRRIMHHTMVHEQFSRFFHGFRRDS-HPM---AVMVACLGAMS  95

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYR------------------NTF 232
               A+   +   T  +  +  ++ LIA++P +AA  Y+                  N  
Sbjct:  96 ----AFYHDSIDITDAKQRMIASIRLIAKVPTLAAMAYKYSIGQPFVYPRNDLSYAANFL 151

Query: 233 HGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVLHADHEGGNVSAHAVRLVG 292
           H    VP E+  KV+ +   LAR+           M     LHADHE  N S   VRL G
Sbjct: 152 HMCFSVPCEEY-KVNPV---LARA-----------MDRIFTLHADHEQ-NASTSTVRLAG 195

Query: 293 SALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLRE 352
           S+ ++P+   AAG+  L GP HG AN+  L+    M +++G+     E +     +   +
Sbjct: 196 SSGANPFACIAAGVACLWGPAHGGANEACLK----MLQEIGSIEKIPEFIARA--KDKND 249

Query: 353 GHVIPGFGHAVLRRTDPRYTAQREF---ALKHL--PHDEMFQLVSKLYEVVPRVLEEQGK 407
              + GFGH V +  DPR    ++     LK L    D +  +  +L ++   + +E   
Sbjct: 250 PFRLMGFGHRVYKNYDPRAKLMQKTCHEVLKELNIKDDPLLDIAMELEKIA--LSDEYFI 307

Query: 408 VKNPWPNVDQHSGILLRYYGLVESNFYTVLF 438
            K  +PNVD +SGI L+  G   +  +TVLF
Sbjct: 308 EKKLYPNVDFYSGITLKALGF-PTEMFTVLF 337


ref|YP_047323.1| methylcitrate synthase (citrate synthase 2) [Acinetobacter sp. ADP1]
emb|CAG69501.1| methylcitrate synthase (citrate synthase 2) [Acinetobacter sp. ADP1]
(364 aa)

Score: 80 bits (196), Expect: 1.35004e-13
Length: 340, Idn/Pos/Gap = 87/151/31 (25%/44%/9%)

Query: 132 LLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESK 191
           LL+ G++P ++++++    LK    +P  +   L++LP    HPM      VS+L   + 
Sbjct:  39 LLVHGKLPNQAELKAYKAKLKALRGLPAALKTALEQLP-PSAHPMDVMRTGVSVLGCLTP  97

Query: 192 MAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGM 251
             E + +   K          A  L+A L ++    Y  + + G+ +  E  +  D +  
Sbjct:  98 EHEDHNEAGAKDI--------ADKLMASLGSMLLYWYHFS-NNGRRIEVETDD--DSIAA 146

Query: 252 RLARSLGFEL--NEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGL 309
                L  E    E+ + M   L+L+A+HE  N S    R+V    SD Y +   G+  L
Sbjct: 147 HFLHLLHGEKPSEEWIQAMHTSLILYAEHEF-NASTFTSRVVAGTGSDMYSAITGGIGAL 205

Query: 310 AGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDP 369
            GP HG AN+        ++++  N      ++R      + +  V+ GFGH V   +DP
Sbjct: 206 RGPKHGGANEVA----FVIQQRYDNADEAEADIR----SRVEKKEVVIGFGHPVYTVSDP 257

Query: 370 RYTAQREFALKHLPHD-EMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGL 428
           R        +K + +D    Q  +K+Y +  R+     +VKN +PN+D  S +     G 
Sbjct: 258 RNE-----VIKKVAYDLAQSQQNTKMYLIAERLEAVMKEVKNMFPNLDWFSAVSYHLMG- 311

Query: 429 VESNFYTVLFGVSRALGTLSSLVWDRALGLPIERPKSVTT 468
           V +  +T LF ++R  G  + ++  R  G  I RP +  T
Sbjct: 312 VPTAMFTPLFVIARTAGWSAHVIEQRQDG-KIIRPSANYT 350


emb|CAB85272.1| citrate synthase [Neisseria meningitidis Z2491]
gb|AAF40869.1| methylcitrate synthase/citrate synthase 2 [Neisseria meningitidis MC58]
ref|NP_284754.1| citrate synthase [Neisseria meningitidis Z2491]
pir||A81200 citrate (si)-synthase (EC 4.1.3.7) NMA2054 [imported] - Neisseria meningitidis (strain MC58 serogroup B, strain Z2491 serogroup A)
ref|NP_273479.1| methylcitrate synthase/citrate synthase 2 [Neisseria meningitidis MC58]
(384 aa)

Score: 80 bits (196), Expect: 1.35004e-13
Length: 341, Idn/Pos/Gap = 89/151/33 (26%/44%/9%)

Query: 132 LLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESK 191
           LL+ G +P + ++ +    LK    +P  V+++L+ LP    HPM      VS+L     
Sbjct:  60 LLIHGHLPNKFELAAYKTKLKSMRGLPIRVIKVLESLP-AHTHPMDVMRTGVSMLGCVHP 118

Query: 192 MAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGM 251
             E++ +   +          A  LIA L ++    Y+ + H GK +  E  E+   +G 
Sbjct: 119 ERESHPESEARDI--------ADKLIASLGSILLYWYQYS-HNGKRIEVESDEET--IGG 167

Query: 252 RLARSL-GFELNEFD-ELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGL 309
              + L G   +E   + M + L+L+A+HE  N S    R++    SD Y S    +  L
Sbjct: 168 HFLQLLHGKRPSESHIKAMHVSLILYAEHEF-NASTFTARVIAGTGSDMYSSITGAIGAL 226

Query: 310 AGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDP 369
            GP HG AN+        ++++  N      ++R    E +    ++ GFGH V   +DP
Sbjct: 227 KGPKHGGANEVA----YDIQKRYRNADEAEADIR----ERIGRKEIVIGFGHPVYTISDP 278

Query: 370 RYTAQREFA--LKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYG 427
           R    +E A  L     D       +L+++  R+     + K  +PN+D  S +  +  G
Sbjct: 279 RNVVIKEVARGLSKETGD------MRLFDIAERLESVMWEEKKMFPNLDWFSAVSYQKLG 332

Query: 428 LVESNFYTVLFGVSRALGTLSSLVWDRALGLPIERPKSVTT 468
            V +  +T LF +SR  G  + ++  R  G  I RP +  T
Sbjct: 333 -VPTAMFTPLFVISRTTGWSAHVLEQRKDG-KIIRPSANYT 371


ref|ZP_00298090.1| COG0372: Citrate synthase [Methanosarcina barkeri str. fusaro]
(355 aa)

Score: 80 bits (196), Expect: 1.53003e-13
Length: 349, Idn/Pos/Gap = 90/162/35 (25%/46%/10%)

Query: 125 LP-EGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAV 183
           LP + + +LL+ G++P + ++      L     V  EV+ ++  + +  +  +      V
Sbjct:  28 LPYDAVSYLLILGDLPGDQELAEYSACLHGEREVNREVIDVI-HMCNFNIDSIEALRTIV  86

Query: 184 SLL-QHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEK 242
           S + Q +  + ++  +G          +  A  LIA++P + A  YR   +G + VP + 
Sbjct:  87 SFISQFDPDINDSSPEGN---------MRKATRLIAKIPTIVAAYYR-IANGKEPVPPDP 136

Query: 243 IEKVDDMGMRLARSLGFELNEFD-ELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLS 301
                   + + R  G +  + + E+M    +L A+HE  N S  + R+  S LSD Y +
Sbjct: 137 SLSHGANFLYMLR--GNKPTQLEAEVMEKDFILSAEHEL-NASTFSSRVTASTLSDLYSA 193

Query: 302 FAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGH 361
             +GL  L GPLHG A  EV      M E++       EN      + L +   I GFGH
Sbjct: 194 VVSGLCTLKGPLHGGARAEV----TAMIEEIA----CPENAENYVLDKLSKKEKIMGFGH 245

Query: 362 AVLRRTDPRYTAQREFA--LKHLPHDEMFQLVSKLYE--VVPRVLEEQGKVKNP-WPNVD 416
            V +  DPR    ++ A  L     D  +  ++++ E  V+  ++E++GK   P +PNVD
Sbjct: 246 RVYKTYDPRGMIFKQLAKQLAEAKGDMHWYNIAEVVENTVIRELVEKKGK---PIYPNVD 302

Query: 417 QHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLPIERPKS 465
            +SG++ +Y   +     T +F + R  G ++   +D+     I RP++
Sbjct: 303 FYSGVIYKYMD-IPPQLATSIFAIGRVSGWIAH-CFDQYEKKKIIRPRA 349


emb|CAD92106.1| citrate synthase [Bartonella schoenbuchensis]
(336 aa)

Score: 79 bits (195), Expect: 1.86925e-13
Length: 332, Idn/Pos/Gap = 93/147/60 (28%/44%/18%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LLL GE+PT+ + +   + +     V  +  R       +  HPM   +V V+ L   S
Sbjct:  40 YLLLYGELPTKQEKDDFDRRIMHHTMVHEQFSRFFHGFRRDS-HPM---AVMVACLGAMS  95

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYR------------------NTF 232
               A+   +   T  +  +  ++ LIA++P +AA  Y+                  N  
Sbjct:  96 ----AFYHDSIDITDAKQRMIASIRLIAKVPTLAAMAYKYSIGQPFVYPRNDLGYAANFL 151

Query: 233 HGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVLHADHEGGNVSAHAVRLVG 292
           H    VP E+  KV+ +   LAR+           M     LHADHE  N S   VRL G
Sbjct: 152 HMCFSVPCEEY-KVNPV---LARA-----------MDRIFTLHADHEQ-NASTSPVRLAG 195

Query: 293 SALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLRE 352
           S+ ++P+   AAG+  L GP HG AN+  L+    M +++G    + E +RE       +
Sbjct: 196 SSGANPFACIAAGVACLWGPAHGGANEACLK----MLQEIG----SIEKIREFIARAKDK 247

Query: 353 GHV--IPGFGHAVLRRTDPRYTAQREF---ALKHL--PHDEMFQLVSKLYEVVPRVLEEQ 405
                + GFGH V +  DPR    ++     LK L    D +  +  +L ++   + +E 
Sbjct: 248 NDPFRLMGFGHRVYKNYDPRAKLMQKTCHEVLKELNIKDDPLLDIAMELEKIA--LSDEY 305

Query: 406 GKVKNPWPNVDQHSGILLRYYGLVESNFYTVL 437
              K  +PNVD +SGI L+  G   +  +TVL
Sbjct: 306 FIEKKLYPNVDFYSGITLKALGF-PTEMFTVL 336


gb|AAQ08230.1| citrate synthase [Rickettsia sp. Rf31]
(387 aa)

Score: 79 bits (195), Expect: 1.88491e-13
Length: 403, Idn/Pos/Gap = 94/173/63 (23%/42%/15%)

Query:  60 VRERFGEEVLDACTVNQAYG------GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQR 112
           ++   GE+V+D   V+          G  S  +     + ++  +GI R RG+ I     
Sbjct:  23 LKASIGEDVIDISRVSSEADCFTYDPGFMSTASCQSTITYINGDKGILRHRGYDI-----  77

Query: 113 LLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHER 172
                K   E+     + +LL+ GE+P+  Q  +  + +   + V            +ER
Sbjct:  78 -----KDLAEKSDFLEVAYLLIYGELPSIEQYNNFTKQVAHHSLV------------NER 120

Query: 173 MHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLE--------DALTLIARLPAVA 224
           +H + Q     +       MA   A     S F+   L          A+ +IA++P +A
Sbjct: 121 LHYLFQ-----TFCSSSHPMAIMLAAVGSLSAFYPDLLNFKEADYELTAIRMIAKIPTIA 175

Query: 225 ARIYRNTFHGGKHVPAEKIEKVDD-MGMRLARS-LGFELNEF--DELMRLYLVLHADHEG 280
           A  Y+ +       P   ++  ++ + M  A     +++N    + L +++ +LHADHE 
Sbjct: 176 AMSYKYSIGQPFIYPDNSLDFTENFLHMMFATPCTKYKVNPIIKNALNKIF-ILHADHEQ 234

Query: 281 GNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTE 340
            N S   VR+ GS+ ++P+   + G+  L GP HG AN+ V+  L ++     N P    
Sbjct: 235 -NASTSTVRIAGSSGANPFACVSTGIASLWGPAHGGANEAVINMLKEIGSS-KNIPKYIA 292

Query: 341 NLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFA------LKHLPHDEMFQLVSKL 394
             ++       +   + GFGH V +  DPR    +E        L  L ++ + Q+  +L
Sbjct: 293 KAKD-----KNDPFRLMGFGHRVYKNYDPRAVVLKETCKEVLKELGQLENNPLLQIAIEL 347

Query: 395 YEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVL 437
             +  +  +E    +  +PNVD +SG++ +  G + S  +TVL
Sbjct: 348 EAIALK--DEYFIERKLYPNVDFYSGVIYKAMG-IPSQMFTVL 387


ref|NP_393647.1| citrate synthase [Thermoplasma acidophilum DSM 1728]
emb|CAA38996.1| citrate synthase [Thermoplasma acidophilum]
emb|CAC11315.1| citrate synthase [Thermoplasma acidophilum]
pir||YKYT citrate (si)-synthase (EC 4.1.3.7) - Thermoplasma acidophilum
sp|P21553|CISY_THEAC Citrate synthase
(385 aa)

Score: 79 bits (195), Expect: 1.91663e-13
Length: 362, Idn/Pos/Gap = 93/156/43 (25%/43%/11%)

Query:  92 SLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQD 150
           + +D  +GI R+ G+S+ +          SG Q   E + +L L G +PTE ++    + 
Sbjct:  22 TTIDGNKGILRYGGYSVEDI-------IASGAQD--EEIQYLFLYGNLPTEQELRKYKET  72

Query: 151 LKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCL 210
           +++   +P  V+  + +LP E      Q +   ++   E+K    + +   +        
Sbjct:  73 VQKGYKIPDFVINAIRQLPRESDAVAMQMAAVAAMAASETKF--KWNKDTDRDV------ 124

Query: 211 EDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMR-LARSLGFELNEFD-ELM 268
             A  +I R+ A+   +YR+      ++PAE  +  D      L  + G +  + + + M
Sbjct: 125 --AAEMIGRMSAITVNVYRHIM----NMPAELPKPSDSYAESFLNAAFGRKATKEEIDAM 178

Query: 269 RLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQM 328
              L+L+ DHE    S  A  +  S LSD Y    A L  L GPLHG A +  +    ++
Sbjct: 179 NTALILYTDHE-VPASTTAGLVAVSTLSDMYSGITAALAALKGPLHGGAAEAAIAQFDEI 237

Query: 329 KEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMF 388
           K+         +N+       +     + GFGH V +  DPR    +  A K        
Sbjct: 238 KDPAMVEKWFNDNI-------INGKKRLMGFGHRVYKTYDPRAKIFKGIAEKLSSKKPE- 289

Query: 389 QLVSKLYEVVPRVLEEQG----KVKNPWPNVDQHSGILLRYYGL-VESNFYTVLFGVSRA 443
             V K+YE+  + LE+ G      K  +PN D  SGI+    G  + +N YT LF +SR 
Sbjct: 290 --VHKVYEIATK-LEDFGIKAFGSKGIYPNTDYFSGIVYMSIGFPLRNNIYTALFALSRV 346

Query: 444 LG 445
            G
Sbjct: 347 TG 348


emb|CAB95653.1| citrate synthase [Bartonella schoenbuchensis]
(344 aa)

Score: 79 bits (195), Expect: 1.96521e-13
Length: 331, Idn/Pos/Gap = 92/146/56 (27%/44%/16%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LLL GE+PT+ +     + +     V  +  R       +  HPM   +V V+ L   S
Sbjct:  45 YLLLYGELPTQQEKADFDRRIMHHTMVHEQFSRFFHGFRRDS-HPM---AVMVACLGAMS 100

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYR------------------NTF 232
               A+   +   T  +  +  ++ LIA++P +AA  Y+                  N  
Sbjct: 101 ----AFYHDSIDITDAKQRMIASIRLIAKVPTLAAMAYKYSIGQPFVYPRNDLGYAANFL 156

Query: 233 HGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVLHADHEGGNVSAHAVRLVG 292
           H    VP E+  KV+ +   LAR+           M     LHADHE  N S   VRL G
Sbjct: 157 HMCFSVPCEEY-KVNPV---LARA-----------MDRIFTLHADHEQ-NASTSTVRLAG 200

Query: 293 SALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLRE 352
           S+ ++P+   AAG+  L GP HG AN+  L+    M +++G+     E +     +   +
Sbjct: 201 SSGANPFACIAAGVACLWGPAHGGANEACLK----MLQEIGSIEKIPEFIARA--KDKND 254

Query: 353 GHVIPGFGHAVLRRTDPRYTAQREF---ALKHL--PHDEMFQLVSKLYEVVPRVLEEQGK 407
              + GFGH V +  DPR    ++     LK L    D +  +  +L ++   + +E   
Sbjct: 255 PFRLMGFGHRVYKNYDPRAKLMQKTCHEVLKELNIKDDPLLDIAMELEKIA--LSDEYFI 312

Query: 408 VKNPWPNVDQHSGILLRYYGLVESNFYTVLF 438
            K  +PNVD +SGI L+  G   +  +TVLF
Sbjct: 313 EKKLYPNVDFYSGITLKALGF-PTEMFTVLF 342


gb|AAG43955.1| citrate synthase [Bartonella henselae subsp. arupensis]
(326 aa)

Score: 79 bits (195), Expect: 2.01502e-13
Length: 317, Idn/Pos/Gap = 85/147/28 (26%/46%/8%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LLL GE+PT+ +     + + +   V  +  R       +  HPM   +V V+ L   S
Sbjct:  28 YLLLYGELPTKQEKSDFDRCIMQHTMVHEQFARFFHGFRRDS-HPM---AVMVACLGAMS  83

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMG 250
               A+   +   T  +  +  ++ LI+++P +AA  Y+ +       P   +    +  
Sbjct:  84 ----AFYHDSIDITDPQQRMIASVRLISKVPTLAAMAYKYSIGQAFVYPRNDLSYAANF- 138

Query: 251 MRLARSLGFELNEFDEL----MRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGL 306
           +R+  S+  E  + + +    M    +LHADHE  N S   VRL GS+ ++P+   AAG+
Sbjct: 139 LRMCFSVPCEEYKTNPVLTRAMDRIFILHADHEQ-NASTSTVRLAGSSGANPFACIAAGV 197

Query: 307 NGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRR 366
             L GP HG AN+  L+    M +++G+     E +     +   +   + GFGH V + 
Sbjct: 198 ACLWGPAHGGANEACLK----MLQEIGSVKRIPEFIARA--KDKNDPFRLMGFGHRVYKN 251

Query: 367 TDPRYTAQREF---ALKHL--PHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGI 421
            DPR    ++     LK L    D +  +  +L ++   + +E    K  +PNVD +SGI
Sbjct: 252 YDPRAKIMQKTCHEVLKELNIQDDPLLDIAIELEKIA--LNDEYFVEKKLYPNVDFYSGI 309

Query: 422 LLRYYGLVESNFYTVLF 438
            L+  G   +  +TVLF
Sbjct: 310 TLKALGF-PTEMFTVLF 325


ref|ZP_00306000.1| COG0372: Citrate synthase [Ferroplasma acidarmanus]
(372 aa)

Score: 79 bits (195), Expect: 2.04893e-13
Length: 381, Idn/Pos/Gap = 95/168/52 (24%/44%/13%)

Query:  80 GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEI 138
           G+ ++     E + +D Q+GI R+RG+ I E            E+   E + +L+L G+ 
Sbjct:   7 GLENVYIKYTELTFIDGQKGIMRYRGYDINEL----------AEKSSFEKVSYLMLFGKF  56

Query: 139 PTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQ 198
           P +S++++    +    A        LD+   + +  M + S ++ +LQ         + 
Sbjct:  57 PDDSELKNFQNKINSHLA--------LDDYLKDILRAMPETSDSLGILQ------TLLSA 102

Query: 199 GAPKSTFWEYCLED----ALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLA 254
            A K + ++Y  E+       ++  + ++ A IYR    G   +  E  E   +  ++ A
Sbjct: 103 KASKESNYKYTKENDGEKIPEILGSVLSMVANIYRLK-SGNNIIDPEPGESYAETFLK-A 160

Query: 255 RSLGFELNEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLH 314
            S   + N+    M   L+L+ DHE    S  A  +  S LSD Y S A+ +  L GPLH
Sbjct: 161 CSGSADKNKISA-MDSALILYMDHEI-PASTTAALVTASTLSDMYSSLASAIAALRGPLH 218

Query: 315 GLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREG-HVIPGFGHAVLRRTDPRYTA 373
           G A +   R  L++ E         EN+       +  G   + GFGH V R  DPR   
Sbjct: 219 GGAAEGAYRQFLEIGEP--------ENVNAWFENNILNGKRRLVGFGHRVYRTYDPRLKT 270

Query: 374 QREFALKHLPHDEMFQLVSKLYEVVPRVLEEQG----KVKNPWPNVDQHSGILLRYYGLV 429
            +++A      +E  ++++     + + LEE G      K  + N D ++G++    G  
Sbjct: 271 FKKYADILSTTEEQKKILA-----IAKRLEEAGVKAFGSKGIYTNTDFYAGMVFNAIGF- 324

Query: 430 ESNFYTVLFGVSRALGTLSSL 450
             + +T LFG+SR  G L+ +
Sbjct: 325 PVDMFTTLFGLSRISGILAHI 345


ref|YP_199532.1| citrate synthase 2 [Xanthomonas oryzae pv. oryzae KACC10331]
gb|AAW74147.1| citrate synthase 2 [Xanthomonas oryzae pv. oryzae KACC10331]
(389 aa)

Score: 79 bits (194), Expect: 2.0661e-13
Length: 344, Idn/Pos/Gap = 90/146/29 (26%/42%/8%)

Query: 127 EGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLL 186
           E + +LL+ G++P   ++      L+    VP  V   L++LP    HPM      VS+L
Sbjct:  59 EEIAYLLVHGKLPNSGELRGYKAKLRSLRGVPAAVKAALEQLP-PSAHPMDVMRTGVSVL 117

Query: 187 QHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKV 246
                  + +     +          A  L+A L ++    Y  + H GK +  E  +  
Sbjct: 118 GCLQPEKDDHNHPGARDI--------ADKLMASLGSMLLYWYHYS-HNGKRIDVETDD-- 166

Query: 247 DDMGMRLARSL-GFELNE-FDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAA 304
           D +G      L GF   + +   M   L+L+A+HE  N S  A R++    SD Y + A 
Sbjct: 167 DSIGGHFLHLLHGFAPKDAWVRAMHTSLILYAEHEF-NASTFASRVIAGTGSDMYSAIAG 225

Query: 305 GLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVL 364
           G+  L GP HG AN+           ++  R  T +         +    V+ GFGH V 
Sbjct: 226 GIGALRGPKHGGANEVAF--------EVQKRYDTPDEAEADIKARVERKEVVIGFGHPVY 277

Query: 365 RRTDPRYTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLR 424
             +DPR    ++ A +    DE  Q   K+Y++  R+      +K  +PN+D  S +   
Sbjct: 278 TLSDPRNKVIKDVAREL--SDE--QGSRKMYDIAERLESVMWDIKKMFPNLDWFSAVSYH 333

Query: 425 YYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLPIERPKSVTT 468
             G V +  +T LF ++R  G  + ++  R  G  I RP +  T
Sbjct: 334 MMG-VPTAMFTPLFVLARTAGWSAHIIEQRVDG-KIIRPSANYT 375


ref|NP_737328.1| putative citrate synthase [Corynebacterium efficiens YS-314]
dbj|BAC17528.1| putative citrate synthase [Corynebacterium efficiens YS-314]
(382 aa)

Score: 79 bits (194), Expect: 2.20872e-13
Length: 361, Idn/Pos/Gap = 93/156/49 (25%/43%/13%)

Query: 107 IPECQRLLPRAKPSG---EQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLR 163
           +PE   L  R  P     E    E +++LL  GE+PT  Q+       +    +   ++ 
Sbjct:  26 MPETNSLTYRGYPVQDLVEHCSFEEVIYLLWNGELPTAEQLREFNTRGRSYRVLDAGLIA  85

Query: 164 LLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAV 223
           L+  LP    HPM     AVS +   +K  E +  GA      ++ L     L+A+LP V
Sbjct:  86 LIHSLPMG-CHPMDVLRTAVSYMG--TKDPEPFTTGA------DHVLRIGHNLLAQLPMV 136

Query: 224 AARIYRNTFHGGKHVPAEKIEKVDDMGMR---LARSLGF----------ELNEFDELMRL 270
            A   R      +   A+ I    D G+    L+   G           ++ +F++    
Sbjct: 137 VAMDIR------RRSGADIIAPDPDKGIAENFLSMVFGTASASVATNPEDVRDFEK---- 186

Query: 271 YLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKE 330
            L+L+A+H   N S    R++ S  SD Y + A  +  L GPLHG AN+ V+  +L + +
Sbjct: 187 SLILYAEHSF-NASTFTSRVITSTRSDAYSAIAGAIGALKGPLHGGANEFVMHTMLDIDD 245

Query: 331 KLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQL 390
                    +N        L    +I GFGH V +  D R  +  E +++ L      + 
Sbjct: 246 P--------DNAAAWVHRALDNKDLIMGFGHRVYKSGDSRVPSM-EKSMRALAQRHDAEK 296

Query: 391 VSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSL 450
             ++YE + +V+E++  +K   PN+D  +G      G    +F+T LF ++R  G  + +
Sbjct: 297 WVRMYEQMQQVMEDRTGIK---PNLDFPAGPAYHILGF-PVDFFTPLFVLARLAGWTAHI 352

Query: 451 V 451
           V
Sbjct: 353 V 353


ref|NP_907612.1| CITRATE SYNTHASE [Wolinella succinogenes DSM 1740]
emb|CAE10512.1| CITRATE SYNTHASE [Wolinella succinogenes]
(422 aa)

Score: 78 bits (193), Expect: 2.81337e-13
Length: 330, Idn/Pos/Gap = 91/147/54 (27%/44%/16%)

Query: 139 PTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQ 198
           PT+ + +   ++L RR+ +   + +++D  P +  HPM   S +VS L            
Sbjct:  98 PTKEESDQFERELVRRSYIHEGLRKIIDAFP-DGAHPMANLSSSVSAL------------ 144

Query: 199 GAPKSTFW------EYCLED---ALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDD- 248
               STF+      EY  E    A  +IA+ P +AA  YR++       P      V++ 
Sbjct: 145 ----STFYYDHIDMEYEAEYQTMARRIIAKTPTLAAFAYRSSVGSPFVYPDADRGYVENF 200

Query: 249 MGMRLARSLG--------FELNEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYL 300
           + M  A   G         E++  D +     +LHADH G N S   VR V S    PY 
Sbjct: 201 LYMLRAYPHGKLKEEISPIEVSALDTI----FMLHADH-GQNASTATVRNVASTGVHPYA 255

Query: 301 SFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFG 360
           + +AGL+ L G  HG AN+ V+  L    E +G+       + +   +   +   + GFG
Sbjct: 256 ALSAGLSALWGKAHGGANESVMDQL----EMIGDVKNVDRYIAKA--KDKNDSFRLMGFG 309

Query: 361 HAVLRRTDPRYTAQREFALKHLPHDEMFQLVSKLYEVVPRVLE-----EQGKVKNPWPNV 415
           H V +  DPR    R+  LK     +  ++  +L E+  ++ E     E    ++ +PNV
Sbjct: 310 HRVYKSYDPRARILRK--LKDDLDQKGVKMNQRLVEIAEKIEEVATQDEYFLSRSLYPNV 367

Query: 416 DQHSGILLRYYGLVESNFYTVLFGVSRALG 445
           D +SGI+L    + +S F T +F + R  G
Sbjct: 368 DFYSGIILTALKIPKSMF-TPIFAIGRMPG 396


emb|CAB12783.1| citrate synthase I [Bacillus subtilis subsp. subtilis str. 168]
ref|NP_388825.1| citrate synthase I [Bacillus subtilis subsp. subtilis str. 168]
emb|CAA74489.1| Citrate synthase I [Bacillus subtilis]
pir||I40380 citrate (si)-synthase (EC 4.1.3.7) citA [validated] - Bacillus subtilis
sp|P39119|CISY_BACSU Citrate synthase I
gb|AAA20936.1| citrate synthase I
(366 aa)

Score: 78 bits (193), Expect: 2.88468e-13
Length: 345, Idn/Pos/Gap = 89/151/31 (25%/43%/8%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +L+L G++P+  +++     L     +P  + RL+  LP+     M   SV  +++   S
Sbjct:  47 YLILFGKLPSTEELQVFKDKLAAERNLPEHIERLIQSLPNN----MDDMSVVRTVV---S  99

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHV--PAEKIEKVDD 248
            + E      PK+       E+A+ LIA  P++ A  YR  +  G+    P+ +   V++
Sbjct: 100 ALGENTYTFHPKT-------EEAIRLIAITPSIIA--YRKRWTRGEQAIAPSSQYGHVEN 150

Query: 249 MGMRLARSLGFELNEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNG 308
               L      E  +  + +  Y++L  +H G N S  + R+  S  SD   +  A L  
Sbjct: 151 YYYMLTGEQPSEAKK--KALETYMILATEH-GMNASTFSARVTLSTESDLVSAVTAALGT 207

Query: 309 LAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTD 368
           + GPLHG A   V + L  + EK        E+      E L +G  + GFGH V +  D
Sbjct: 208 MKGPLHGGAPSAVTKMLEDIGEK--------EHAEAYLKEKLEKGERLMGFGHRVYKTKD 259

Query: 369 PRYTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGL 428
           PR  A R+ A +   +D    L   +     R+LE     +  + NV+ ++  ++R    
Sbjct: 260 PRAEALRQKAEEVAGNDRDLDLALHVEAEAIRLLEIYKPGRKLYTNVEFYAAAVMRAIDF 319

Query: 429 VESNFYTVLFGVSRALGTLSSLVWDRALGLPIERPKSVTTQWIRE 473
            +   +T  F  SR +G  +  V ++A    I RP +  T  I E
Sbjct: 320 -DDELFTPTFSASRMVGWCAH-VLEQAENNMIFRPSAQYTGAIPE 362


ref|NP_280766.1| CitZ [Halobacterium sp. NRC-1]
gb|AAG20246.1| citrate synthase; CitZ [Halobacterium sp. NRC-1]
pir||B84360 citrate synthase [imported] - Halobacterium sp. NRC-1
(376 aa)

Score: 78 bits (193), Expect: 3.10964e-13
Length: 330, Idn/Pos/Gap = 91/141/45 (27%/42%/13%)

Query: 127 EGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLL 186
           E +L+LL  G++PT S++++   D+     +  +VL L++ L      PM     A S L
Sbjct:  46 EEVLYLLWHGDLPTRSELDAFRADMASHREIDDDVLALVENLAAADADPMAALRTAASAL 105

Query: 187 QHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKV 246
                 A        +        E    + A+LP + A   R     G  V A +    
Sbjct: 106 SAHDDTAGGSDPDDAR--------ESGKRITAKLPTIVAAFTR--LRNGDDVVAPR---- 151

Query: 247 DDMGMRLARSLGFELN---EFDELMRLY---LVLHADHEGGNVSAHAVRLVGSALSDPYL 300
           DD+G   A +  + LN     D L  ++   LVLHADH G N S  +  +  S L+D + 
Sbjct: 152 DDLGH--AANFLYMLNGEAPDDVLADVFDQALVLHADH-GLNASTFSGMVTASTLADVHA 208

Query: 301 SFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCW--ETLREGHVIPG 358
           +  + +  L+G LHG AN  V+R L ++ +          +   L W  + L  G  + G
Sbjct: 209 AVTSAIGTLSGSLHGGANANVMRMLKEVDD---------SDKDPLSWVQDALANGERVMG 259

Query: 359 FGHAVLRRTDPR--YTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVD 416
           FGH V    DPR    ++R   L     D      +K YE+   + +     K   PNVD
Sbjct: 260 FGHRVYNVKDPRAHILSERSEELGAAAGD------TKWYEMSVAIEDYMADEKGLAPNVD 313

Query: 417 QHSGILLRYYGL-VESNFYTVLFGVSRALG 445
            +S     YY + +  + YT +F +SR  G
Sbjct: 314 FYSAS--TYYQMGIPVDIYTPIFAMSRVGG 341


ref|ZP_00267781.1| COG0372: Citrate synthase [Rhodospirillum rubrum]
(386 aa)

Score: 78 bits (193), Expect: 3.32429e-13
Length: 330, Idn/Pos/Gap = 88/141/28 (26%/42%/8%)

Query: 127 EGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLL 186
           E +  LL+ G +PT +Q  S    LK    +P  V   L+ +P    HPM      VS L
Sbjct:  51 EEIAHLLIHGGLPTAAQYASYKAKLKVSRGLPRSVKEALETIP-AAAHPMDVMRSGVSAL 109

Query: 187 QHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKV 246
                + EAY      +       + A  LIA L ++    Y    HG + +  E  E  
Sbjct: 110 G--CALPEAYDHHPVDAR------DIADRLIASLGSMLLYWYHYAHHG-RRIEVETDE-- 158

Query: 247 DDMGMRLARSLGFE--LNEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAA 304
           D +G    R L  +   ++F + M   L+L+A+HE  N S    R++    SD Y   + 
Sbjct: 159 DSIGGHFLRLLHGKPPSDDFVQAMHTSLILYAEHEF-NASTFTARVIAGTGSDMYSCISG 217

Query: 305 GLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVL 364
            +  L GP HG AN+        ++++  +     E++R      +    V+ GFGH V 
Sbjct: 218 AIGALRGPKHGGANEVA----FGIQKRYASLQHAEEDIR----RRVEAKEVVIGFGHPVY 269

Query: 365 RRTDPRYTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLR 424
              DPR    +  A K L  +    L    Y+V  R+ +     K  +PN+D +S +   
Sbjct: 270 TTADPRNAVIKRVA-KGLADEVRSHL---QYDVAERIEQVMWDTKAMFPNLDWYSAVSYH 325

Query: 425 YYGLVESNFYTVLFGVSRALGTLSSLVWDR 454
             G V ++ +T LF ++R  G  + ++  R
Sbjct: 326 LMG-VPTSMFTPLFVIARTCGWAAHVIEQR 354


emb|CAA93835.1| citrate synthase [Bartonella taylorii]
sp|Q59258|CISY_BARTA Citrate synthase
(322 aa)

Score: 78 bits (192), Expect: 3.7362e-13
Length: 310, Idn/Pos/Gap = 84/142/33 (27%/45%/10%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LLL GE+PT+ +     + + +   V  +  R       +  HPM   +V V+ L   S
Sbjct:  31 YLLLYGELPTKQEKHDFDRCIMQHTMVHEQFARFFHGFRRDS-HPM---AVMVACLGAMS  86

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMG 250
               A+   +   T  +  +  ++ LI+++P +AA  Y+ +       P   +    +  
Sbjct:  87 ----AFYHDSIDITDPQQRMIASVRLISKVPTLAAMAYKYSIGQAFVYPRNDLSYAANF- 141

Query: 251 MRLARSL---GFELNE-FDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGL 306
           +R+  S+   G+ +N      M     LHADHE  N S   VRL GS+ ++P+   AAG+
Sbjct: 142 LRMCFSVPCEGYNINSVLTRAMDRIFTLHADHEQ-NASTSTVRLAGSSGANPFACIAAGV 200

Query: 307 NGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREG---HVIPGFGHAV 363
             L GP HG AN+  L+    M +++G    + E + E       +    H++ GFGH V
Sbjct: 201 ACLWGPAHGGANEACLK----MLQEIG----SVERIPEFIARAKDKNDPFHLM-GFGHRV 251

Query: 364 LRRTDPRYTAQREF---ALKHL--PHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQH 418
            +  DPR    ++     LK L    D +  +  +L ++   + +E    K  +PNVD +
Sbjct: 252 YKNYDPRAKIMQKTCHEVLKELNIQDDPLLDIAMELEKIA--LNDEYFVEKKLYPNVDFY 309

Query: 419 SGILLRYYGL 428
           SGI L+  G 
Sbjct: 310 SGITLKALGF 319


gb|AAG59873.1| citrate synthase [Ehrlichia sp. EHt224]
(396 aa)

Score: 78 bits (192), Expect: 4.16426e-13
Length: 401, Idn/Pos/Gap = 100/174/58 (24%/43%/14%)

Query:  65 GEEVLDACTVNQAYG------GMRSLKAMVYETSLLDPQEGIR-FRGFSIPECQRLLPRA 117
           G +V+D  ++ ++ G      G  S  A   + + +D  +GI  +RG++I +   L+   
Sbjct:  12 GNKVVDITSLYKSTGILTYDPGFMSTAACESKITFIDGSKGILCYRGYNIAD---LVNSN  68

Query: 118 KPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMT 177
           K   E      +++LL  G  P+    +     + +    P  +  ++     +  HPMT
Sbjct:  69 KSFIE------IVYLLFYGSFPSVDDFKDFMLQISQEYMPPKMICDVIKSFSQD-AHPMT 121

Query: 178 QFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKH 237
                  L+   S +A  Y          E  L+ A   ++++  + A IYR       H
Sbjct: 122 ------ILMACFSGLASYYNN----QQHCENELKYARLAVSQIAGIIAMIYR-------H 164

Query: 238 VPAEKIEKVDDMGMRLARSLGFELNEFD-----------ELMRLYLVLHADHEGGNVSAH 286
           +  +   + +     L+ S  F    FD           + + +  +LHADHE  N S  
Sbjct: 165 ITDQDFIQAN---TELSYSENFIHMMFDISSYEFTKIVSKALDIIFILHADHEQ-NASTA 220

Query: 287 AVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELC 346
            VRL GS  ++ +   AAG   L GP HG AN+ V+  L+++ E+  N     + +++  
Sbjct: 221 TVRLTGSTGANLFACLAAGAATLWGPAHGGANEAVINMLMEI-EQPSNVKQFVQKVKD-- 277

Query: 347 WETLREGHVIPGFGHAVLRRTDPRYTAQREFALKHLPHDEMFQ-LVSKLYEVVPRVLEEQ 405
                 G  + GFGH V +  DPR     E   + L   ++   L+    E+    L++ 
Sbjct: 278 ---KNNGIRLMGFGHRVYKNYDPRAKIICEICKEVLKDLKVSHPLLEIALELENIALQDS 334

Query: 406 GKV-KNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALG 445
             + +N +PNVD +SGI+L+  G+  S F T LF ++R  G
Sbjct: 335 YFIERNLYPNVDFYSGIVLKAIGIPVSMF-TTLFALARTSG 374


gb|AAP78090.1| citrate synthase [Helicobacter hepaticus ATCC 51449]
ref|NP_861024.1| citrate synthase [Helicobacter hepaticus ATCC 51449]
(427 aa)

Score: 78 bits (192), Expect: 4.34166e-13
Length: 340, Idn/Pos/Gap = 90/147/41 (26%/43%/12%)

Query: 132 LLLTGEIP-TESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLL---- 186
           LL+TGE+P  E++ +    +L  R+ +   ++ + +  P +  HPM   S ++S L    
Sbjct:  89 LLITGEVPKNETETKEFEIELVHRSFLNEGLINIFNAFP-DSAHPMANLSASLSALSTFH 147

Query: 187 -------QHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVP 239
                    E +   A    A   T   +    +L +    P VA     N  +  +  P
Sbjct: 148 FRHLDMGNEEERQVMARRAIAKIPTLAAFSYRHSLGIPYIYPDVARGYVENFLYMLRAYP 207

Query: 240 AEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPY 299
             K++      + +      E+   D++      LHADH G N S   VR V S  + PY
Sbjct: 208 GGKMKHTIKGEVEITP---LEIEALDKI----FTLHADH-GQNASTTTVRNVASTGAHPY 259

Query: 300 LSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGF 359
            + +AG+N L G  HG AN++V    L M  ++G+     + + +   +   +   + GF
Sbjct: 260 AALSAGVNALWGAAHGGANEKV----LDMLNEIGDAKNVDKFINKA--KDKNDPFRLMGF 313

Query: 360 GHAVLRRTDPRYTAQREFALKHLPHD------EMFQLVSKLYEVVPRV-LEEQGKV-KNP 411
           GH V +  DPR        LK L  D      +M   +S L   V  V L +   V +N 
Sbjct: 314 GHRVYKNYDPRAK-----ILKKLKDDLDAKGIKMNTRLSDLAHKVEEVALSDSYFVERNL 368

Query: 412 WPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLV 451
           +PNVD +SGI+L    +  S  +T +F + R  G  + L+
Sbjct: 369 YPNVDFYSGIILSALKIPVS-LFTPIFVIGRMPGWCAQLL 407


pdb|1A59| Cold-Active Citrate Synthase
(378 aa)

Score: 78 bits (191), Expect: 4.68024e-13
Length: 371, Idn/Pos/Gap = 98/163/47 (26%/43%/12%)

Query: 102 FRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEV 161
           +RG+ + E       AK S EQ     + +LL   E+P +S++++   + +R      E 
Sbjct:  31 YRGYPVQELA-----AKCSFEQ-----VAYLLWNSELPNDSELKAFV-NFERSHRKLDEN  79

Query: 162 LRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLP 221
           ++   +L     HPM     AVS+L      A+     +P++      LE A++L+A  P
Sbjct:  80 VKGAIDLLSTACHPMDVARTAVSVLGANHARAQ---DSSPEAN-----LEKAMSLLATFP 131

Query: 222 AVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELN-EFDELMRLYLVLHADHEG 280
           +V A  Y      G+ +  E  E +D     L  + G E   E  E   + ++L+A+H  
Sbjct: 132 SVVA--YDQRRRRGEEL-IEPREDLDYSANFLWMTFGEEAAPEVVEAFNVSMILYAEHSF 188

Query: 281 GNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNR---PM 337
            N S    R++ S L+D + +    +  L GPLHG AN+ V+       E++G R    +
Sbjct: 189 -NASTFTARVITSTLADLHSAVTGAIGALKGPLHGGANEAVMHTF----EEIGIRKDESL 243

Query: 338 TTENLRELCW--ETLREGHVIPGFGHAVLRRTDPRYTAQR---EFALKHLPHDEMFQLVS 392
                R   W  + L +   + GFGH V +  D R    +   +  +KH    EM     
Sbjct: 244 DEAATRSKAWMVDALAQKKKVMGFGHRVYKNGDSRVPTMKSALDAMIKHYDRPEML---- 299

Query: 393 KLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSL-- 450
            LY  +   +EE  ++K   PN+D  +G      G  ++  +T LF  +R  G  + +  
Sbjct: 300 GLYNGLEAAMEEAKQIK---PNLDYPAGPTYNLMGF-DTEMFTPLFIAARITGWTAHIME 355

Query: 451 -VWDRALGLPI 460
            V D AL  P+
Sbjct: 356 QVADNALIRPL 366


gb|AAC45662.1| citrate synthase [Antarctic bacterium DS2-3R]
sp|O34002|CISY_ABDS2 Citrate synthase
(379 aa)

Score: 78 bits (191), Expect: 4.79887e-13
Length: 371, Idn/Pos/Gap = 98/163/47 (26%/43%/12%)

Query: 102 FRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEV 161
           +RG+ + E       AK S EQ     + +LL   E+P +S++++   + +R      E 
Sbjct:  32 YRGYPVQELA-----AKCSFEQ-----VAYLLWNSELPNDSELKAFV-NFERSHRKLDEN  80

Query: 162 LRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLP 221
           ++   +L     HPM     AVS+L      A+     +P++      LE A++L+A  P
Sbjct:  81 VKGAIDLLSTACHPMDVARTAVSVLGANHARAQ---DSSPEAN-----LEKAMSLLATFP 132

Query: 222 AVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELN-EFDELMRLYLVLHADHEG 280
           +V A  Y      G+ +  E  E +D     L  + G E   E  E   + ++L+A+H  
Sbjct: 133 SVVA--YDQRRRRGEEL-IEPREDLDYSANFLWMTFGEEAAPEVVEAFNVSMILYAEHSF 189

Query: 281 GNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNR---PM 337
            N S    R++ S L+D + +    +  L GPLHG AN+ V+       E++G R    +
Sbjct: 190 -NASTFTARVITSTLADLHSAVTGAIGALKGPLHGGANEAVMHTF----EEIGIRKDESL 244

Query: 338 TTENLRELCW--ETLREGHVIPGFGHAVLRRTDPRYTAQR---EFALKHLPHDEMFQLVS 392
                R   W  + L +   + GFGH V +  D R    +   +  +KH    EM     
Sbjct: 245 DEAATRSKAWMVDALAQKKKVMGFGHRVYKNGDSRVPTMKSALDAMIKHYDRPEML---- 300

Query: 393 KLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSL-- 450
            LY  +   +EE  ++K   PN+D  +G      G  ++  +T LF  +R  G  + +  
Sbjct: 301 GLYNGLEAAMEEAKQIK---PNLDYPAGPTYNLMGF-DTEMFTPLFIAARITGWTAHIME 356

Query: 451 -VWDRALGLPI 460
            V D AL  P+
Sbjct: 357 QVADNALIRPL 367


emb|CAA93834.1| citrate synthase [Bartonella sp.]
(322 aa)

Score: 78 bits (191), Expect: 4.83908e-13
Length: 307, Idn/Pos/Gap = 79/141/27 (25%/45%/8%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LLL GE+PT+ +     + + +   V  +  R       +  HPM   +V V+ L   S
Sbjct:  31 YLLLYGELPTKQEKNDFDRCIMQHTMVHEQFARFFHGFRRDS-HPM---AVMVACLGAMS  86

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMG 250
               A+   +   T  +  +  ++ LI+++P +AA  Y+ +       P   +    +  
Sbjct:  87 ----AFYHDSIDITDPQQRMIASVRLISKVPTLAAMAYKYSIGQAFVYPRNDLSYAANF- 141

Query: 251 MRLARSLGFELNEFDEL----MRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGL 306
           +R+  S+  E  + + +    M    +LHADHE  N S   VRL GS+ ++P+   AAG+
Sbjct: 142 LRMCFSVPCEEYKTNPVLTRAMDQIFILHADHEQ-NASTSTVRLAGSSGANPFACIAAGV 200

Query: 307 NGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRR 366
             L+GP HG AN+  L+    M +++G+     E +     +   +   + GFGH V + 
Sbjct: 201 ACLSGPAHGGANEACLK----MLQEIGSVKRIPEFIARA--KDKNDPFRLMGFGHRVYKN 254

Query: 367 TDPRY-----TAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGI 421
            DPR      T  +     ++  D +  +  +L ++   + +E    K  +PNVD +SGI
Sbjct: 255 YDPRAKIMQKTCHKVLKELNIQDDPLLDIAIELEKIA--LNDEYFVEKKLYPNVDFYSGI 312

Query: 422 LLRYYGL 428
            L+  G 
Sbjct: 313 TLKALGF 319


gb|AAS89948.1| GltA [Bartonella rattimassiliensis]
(334 aa)

Score: 78 bits (191), Expect: 5.17312e-13
Length: 312, Idn/Pos/Gap = 80/142/27 (25%/45%/8%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LLL GE+PT+ +     Q + +   V  +  R       +  HPM   +V VS L   S
Sbjct:  39 YLLLYGELPTQQEKSDFDQCIMQHTMVHEQFARFFHGFRRDS-HPM---AVMVSCLGAMS  94

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMG 250
               A+   +   T  +  +  ++ LI+++P +AA  Y+ +       P   +    +  
Sbjct:  95 ----AFYHDSIDITDPQQRMIASIRLISKVPTLAAMAYKYSIGQPFVYPRNDLSYAANF- 149

Query: 251 MRLARSLGFELNEFDEL----MRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGL 306
           +R+  ++  E  + + +    M    +LHADHE  N S   VRL GS+ ++P+   AAG+
Sbjct: 150 LRMCFAVPCEEYKTNPVLARAMDQIFILHADHEQ-NASTSTVRLAGSSGANPFACIAAGV 208

Query: 307 NGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRR 366
             L GP HG AN+  L+    M +++G+     E +     +   +   + GFGH V + 
Sbjct: 209 ACLWGPAHGGANEACLK----MLQEIGSIKRIPEFIARA--KDKNDPFRLIGFGHRVYKN 262

Query: 367 TDPRY-----TAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGI 421
            DPR      T  +     ++  D +  +  +L ++   + ++    K  +PNVD +SGI
Sbjct: 263 YDPRAKIMQKTCHKVLKELNIQDDPLLDIAIELEKIA--LSDKYFIEKKLYPNVDFYSGI 320

Query: 422 LLRYYGLVESNF 433
           +L+  G     F
Sbjct: 321 ILKALGFPTEMF 332


ref|NP_110758.1| Citrate synthase [Thermoplasma volcanium GSS1]
dbj|BAB59383.1| citrate synthase [Thermoplasma volcanium GSS1]
(386 aa)

Score: 78 bits (191), Expect: 5.26017e-13
Length: 381, Idn/Pos/Gap = 92/162/43 (24%/42%/11%)

Query:  73 TVNQAYGGMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLW 131
           T  +   G+  +       + +D  +GI R+ G+S+ +          +G Q   E + +
Sbjct:   4 TTEEISKGLEDVNIKWTRLTTIDGNKGILRYGGYSVEDIIN-------NGAQA--EEIQY  54

Query: 132 LLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESK 191
           L L GE+P   +++   +++++   +P  V+  + +LP E      Q +   S+   E K
Sbjct:  55 LFLYGELPNAQELKIFKENVQKGYNIPDFVINSIRQLPRESDAVAMQMAAVASMAASEIK 114

Query: 192 MAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMG- 250
               + +   +          A  +I  + A+ A +YR+       +PAE+ +  D    
Sbjct: 115 FK--WNKDTDRDV--------AAQMIGSMSAITANVYRHILG----MPAERPKPSDSYAE 160

Query: 251 --MRLARSLGFELNEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNG 308
             ++ A        E D +    L+L+ DHE    S  A  +  S LSD Y    A L  
Sbjct: 161 SFLKAAFGRNVTKEEVDAI-NTALILYTDHEV-PASTTAGLVAVSTLSDIYSGITAALAA 218

Query: 309 LAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTD 368
           L GPLHG A +  +    ++KE         +N+       +     + GFGH V +  D
Sbjct: 219 LKGPLHGGAAEAAIAQFDEIKEPSNVEKWFNDNI-------INGKKRLMGFGHRVYKTYD 271

Query: 369 PRYTAQREFALKHLPHDEMFQLVSKLYEVVPRVLE---EQGKVKNPWPNVDQHSGILLRY 425
           PR    +  A ++L  +     V K+Y++  ++ +   +Q   K  +PN D  SGI+   
Sbjct: 272 PRAKIFKGIA-ENLSKNN--AEVKKIYDIATKLEDLGVKQFGSKGIYPNTDYFSGIVYMS 328

Query: 426 YGL-VESNFYTVLFGVSRALG 445
            G  + +N YT LF +SR  G
Sbjct: 329 VGFPLRNNIYTALFALSRVTG 349


gb|AAC44815.1| PrpC [Salmonella typhimurium]
(389 aa)

Score: 78 bits (191), Expect: 5.30424e-13
Length: 325, Idn/Pos/Gap = 84/137/28 (25%/42%/8%)

Query: 132 LLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESK 191
           LL+ G++PT  ++ +    LK    +P  V  +L+ LP    HPM      VS L     
Sbjct:  64 LLIHGKLPTRDELNAYKSKLKALRGLPANVRTVLEALPAAS-HPMDVMRTGVSALGCTLP 122

Query: 192 MAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGM 251
             E +     +          A  L+A L ++    Y  + H G+ +  E  +  D +G 
Sbjct: 123 EKEGHTVSGARDI--------ADKLLASLNSILLYWYHYS-HNGERIQPETDD--DSIGG 171

Query: 252 RLARSLGFE--LNEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGL 309
                L  E     +++ M + LVL+A+HE  N S    R++    SD Y +    +  L
Sbjct: 172 HFLHLLHGEKPTQSWEKAMHISLVLYAEHEF-NASTFTSRVIAGTGSDVYSAIIGAIGAL 230

Query: 310 AGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDP 369
            GP HG AN+  L        ++  R  T +       + +    V+ GFGH V    DP
Sbjct: 231 RGPKHGGANEVSL--------EIQQRYETPDEAEADIRKRVENKEVVIGFGHPVYTIADP 282

Query: 370 RYTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLV 429
           R+   +  A K L  +E   L  K+Y +  R+     + K  +PN+D  S +     G V
Sbjct: 283 RHQVIKRVA-KQLS-EEGGSL--KMYHIADRLETVMWETKKMFPNLDWFSAVSYNMMG-V 337

Query: 430 ESNFYTVLFGVSRALGTLSSLVWDR 454
            +  +T LF ++R  G  + ++  R
Sbjct: 338 PTEMFTPLFVIARVTGWAAHIIEQR 362


gb|AAB41629.1| putative citrate synthase [Acidithiobacillus ferrooxidans]
pir||D59237 probable citrate synthase (EC 4.1.3.-) [imported] - Thiobacillus ferrooxidans
sp|P51045|CISY_THIFE Citrate synthase
(386 aa)

Score: 77 bits (190), Expect: 6.58928e-13
Length: 405, Idn/Pos/Gap = 107/174/57 (26%/42%/14%)

Query:  80 GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEI 138
           G+  + A     S +D   G+  +RGF+I +       A  S E+     +  LLL G +
Sbjct:   9 GLEGVAATQSSISNIDGAAGLLSYRGFAIADLA-----AHSSFEE-----VALLLLDGVL  58

Query: 139 PTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLL-----QHESKMA 193
           P  + +E     L+    V   V  ++  +P    HPM     AV+ L     Q E   A
Sbjct:  59 PGAADLERFDHGLRAHRQVKYNVREIMKFMP-VTGHPMDMLHCAVASLGMFYPQQELSDA 117

Query: 194 EAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRL 253
           E        +T     +  A+ +IAR+P + A   +  F      P   +    +    L
Sbjct: 118 ER------GNTLHLDAM--AMRIIARMPTIVAMWEQMRFGNDPISPRPDLSHAANFLYML 169

Query: 254 ARSLGFELN-EFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGP 312
           +   G E +    +++   L+LHA+H   N S  +V + GS L++PY      +  LAGP
Sbjct: 170 S---GREPDPAHTKILDSCLILHAEHTI-NASTFSVLVTGSTLTNPYHVIGGAIGTLAGP 225

Query: 313 LHGLANQEVLRWLLQMK--EKLG---NRPMTTENLRELCWETLREGHVIPGFGHAVLRRT 367
           LHG ANQ+V+  L ++   +++G   +R M     +E  W          GFGH + +  
Sbjct: 226 LHGGANQKVVEMLEEISSVQQVGAYLDRKMAN---KEKIW----------GFGHRIYKTR 272

Query: 368 DPRYTAQREFALKHLPHDEMFQLVSKLYEV---VPRVLEEQGKVKNPWPNVDQHSGILLR 424
           DPR    +        H  +    S L+E+   V R   E+   +    NVD +SG+L  
Sbjct: 273 DPRAVILKGMMEDMASHGNLRH--SSLFEIAIEVERQATERLGAQGIHANVDFYSGVLYH 330

Query: 425 YYGLVESNFYTVLFGVSRALGTLSSLVWDRALG-LPIERPKSVTT 468
             G ++++ +T +F ++R+ G L+   W   L    I RP  V T
Sbjct: 331 EMG-IKADLFTPIFAMARSAGWLAH--WREQLADNRIFRPTQVYT 372


emb|CAB95651.1| citrate synthase [Bartonella schoenbuchensis]
(342 aa)

Score: 77 bits (190), Expect: 6.92755e-13
Length: 331, Idn/Pos/Gap = 91/146/56 (27%/44%/16%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LLL GE+PT+ + +   + +     V  +  R       +  HPM   +V V+ L   S
Sbjct:  45 YLLLYGELPTKQEKDDFDRRIMHHTMVHEQFSRFFHGFRRDS-HPM---AVMVACLGAMS 100

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYR------------------NTF 232
               A+   +   T  +  +  ++ LIA++P +AA  Y+                  N  
Sbjct: 101 ----AFYHDSIDITDAKQRMIASIRLIAKVPTLAAMAYKYSIGQPFVYPRNDLSYAANFL 156

Query: 233 HGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVLHADHEGGNVSAHAVRLVG 292
           H    VP E+  KV+ +   LAR+           M     LHADHE  N S   VRL G
Sbjct: 157 HMCFSVPCEEY-KVNPV---LARA-----------MDRIFTLHADHEQ-NASTSTVRLAG 200

Query: 293 SALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLRE 352
           S+ ++P+   AAG+  L GP HG AN+  L+    M +++G+     E +     +   +
Sbjct: 201 SSGANPFACIAAGVACLWGPAHGGANEACLK----MLQEIGSIEKIPEFIARA--KDKND 254

Query: 353 GHVIPGFGHAVLRRTDPRYTAQREF---ALKHL--PHDEMFQLVSKLYEVVPRVLEEQGK 407
              + GFGH V +  DPR    ++     LK L    D +  +  +L ++   + +E   
Sbjct: 255 PFRLMGFGHRVYKNYDPRAKLMQKTCHEVLKELNIKDDPLLDIAMELEKIA--LSDEYFI 312

Query: 408 VKNPWPNVDQHSGILLRYYGLVESNFYTVLF 438
            K  +PNVD +SGI L+  G   +  +TVL 
Sbjct: 313 EKKLYPNVDFYSGITLKALGF-PTEMFTVLL 342


emb|CAB95650.1| citrate synthase [Bartonella schoenbuchensis]
(337 aa)

Score: 77 bits (190), Expect: 7.04412e-13
Length: 331, Idn/Pos/Gap = 91/146/56 (27%/44%/16%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LLL GE+PT+ + +   + +     V  +  R       +  HPM   +V V+ L   S
Sbjct:  40 YLLLYGELPTKQEKDDFDRRIMHHTMVHEQFSRFFHGFRRDS-HPM---AVMVACLGAMS  95

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYR------------------NTF 232
               A+   +   T  +  +  ++ LIA++P +AA  Y+                  N  
Sbjct:  96 ----AFYHDSIDITDAKQRMIASIRLIAKVPTLAAMAYKYSIGQPFVYPRNDLGYAANFL 151

Query: 233 HGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVLHADHEGGNVSAHAVRLVG 292
           H    VP E+  KV+ +   LAR+           M     LHADHE  N S   VRL G
Sbjct: 152 HMCFSVPCEEY-KVNPV---LARA-----------MDRIFTLHADHEQ-NASTSTVRLAG 195

Query: 293 SALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLRE 352
           S+ ++P+   AAG+  L GP HG AN+  L+    M +++G+     E +     +   +
Sbjct: 196 SSGANPFACIAAGVACLWGPAHGGANEACLK----MLQEIGSIEKIPEFIARA--KDKND 249

Query: 353 GHVIPGFGHAVLRRTDPRYTAQREF---ALKHL--PHDEMFQLVSKLYEVVPRVLEEQGK 407
              + GFGH V +  DPR    ++     LK L    D +  +  +L ++   + +E   
Sbjct: 250 PFRLMGFGHRVYKNYDPRAKLMQKTCHEVLKELNIKDDPLLDIAMELEKIA--LSDEYFI 307

Query: 408 VKNPWPNVDQHSGILLRYYGLVESNFYTVLF 438
            K  +PNVD +SGI L+  G   +  +TVL 
Sbjct: 308 EKKLYPNVDFYSGITLKALGF-PTEMFTVLL 337


emb|CAB95652.1| citrate synthase [Bartonella schoenbuchensis]
(341 aa)

Score: 77 bits (190), Expect: 7.34421e-13
Length: 330, Idn/Pos/Gap = 91/146/56 (27%/44%/16%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LLL GE+PT+ + +   + +     V  +  R       +  HPM   +V V+ L   S
Sbjct:  45 YLLLYGELPTKQEKDDFDRRIMHHTMVHEQFSRFFHGFRRDS-HPM---AVMVACLGAMS 100

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYR------------------NTF 232
               A+   +   T  +  +  ++ LIA++P +AA  Y+                  N  
Sbjct: 101 ----AFYHDSIDITDAKQRMIASIRLIAKVPTLAAMAYKYSIGQPFVYPRNDLSYAANFL 156

Query: 233 HGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVLHADHEGGNVSAHAVRLVG 292
           H    VP E+  KV+ +   LAR+           M     LHADHE  N S   VRL G
Sbjct: 157 HMCFSVPCEEY-KVNPV---LARA-----------MDRIFTLHADHEQ-NASTSTVRLAG 200

Query: 293 SALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLRE 352
           S+ ++P+   AAG+  L GP HG AN+  L+    M +++G+     E +     +   +
Sbjct: 201 SSGANPFACIAAGVACLWGPAHGGANEACLK----MLQEIGSIEKIPEFIARA--KDKND 254

Query: 353 GHVIPGFGHAVLRRTDPRYTAQREF---ALKHL--PHDEMFQLVSKLYEVVPRVLEEQGK 407
              + GFGH V +  DPR    ++     LK L    D +  +  +L ++   + +E   
Sbjct: 255 PFRLMGFGHRVYKNYDPRAKLMQKTCHEVLKELNIKDDPLLDIAMELEKIA--LSDEYFI 312

Query: 408 VKNPWPNVDQHSGILLRYYGLVESNFYTVL 437
            K  +PNVD +SGI L+  G   +  +TVL
Sbjct: 313 EKKLYPNVDFYSGITLKALGF-PTEMFTVL 341


gb|AAM36010.1| citrate synthase 2 [Xanthomonas axonopodis pv. citri str. 306]
ref|NP_641474.1| citrate synthase 2 [Xanthomonas axonopodis pv. citri str. 306]
(384 aa)

Score: 77 bits (190), Expect: 7.78593e-13
Length: 344, Idn/Pos/Gap = 90/145/29 (26%/42%/8%)

Query: 127 EGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLL 186
           E + +LL+ G++P   ++      L+    VP  V   L++LP    HPM      VS+L
Sbjct:  54 EEIAYLLVHGKLPNRGELRGYKAKLRSLRGVPAAVKTALEQLP-PSAHPMDVMRTGVSVL 112

Query: 187 QHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKV 246
                  + +     +          A  L+A L ++    Y  + H GK +  E  +  
Sbjct: 113 GCLQPEKDDHNHPGARDI--------ADKLMASLGSMLLYWYHYS-HNGKRIEVETED-- 161

Query: 247 DDMGMRLARSL-GFE-LNEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAA 304
           D +G      L GF   + +   M   L+L+A+HE  N S  A R++    SD Y + A 
Sbjct: 162 DSIGGHFLHLLHGFAPKDSWVRAMHTSLILYAEHEF-NASTFASRVIAGTGSDMYSAIAG 220

Query: 305 GLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVL 364
           G+  L GP HG AN+           ++  R  T +         +    V+ GFGH V 
Sbjct: 221 GIGALRGPKHGGANEVAF--------EVQKRYDTPDEAEADIKARVERKEVVIGFGHPVY 272

Query: 365 RRTDPRYTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLR 424
             +DPR    +  A +    DE  Q   K+Y++  R+      +K  +PN+D  S +   
Sbjct: 273 TVSDPRNKVIKVVAREL--SDE--QGSRKMYDIAERLESVMWDIKKMFPNLDWFSAVSYH 328

Query: 425 YYGLVESNFYTVLFGVSRALGTLSSLVWDRALGLPIERPKSVTT 468
             G V +  +T LF ++R  G  + ++  R  G  I RP +  T
Sbjct: 329 MMG-VPTAMFTPLFVLARTAGWSAHIIEQRVDG-KIIRPSANYT 370


ref|YP_224951.1| METHYLCITRATE SYNTHASE [Corynebacterium glutamicum ATCC 13032]
emb|CAF19365.1| METHYLCITRATE SYNTHASE [Corynebacterium glutamicum ATCC 13032]
dbj|BAB98052.1| Citrate synthase [Corynebacterium glutamicum ATCC 13032]
gb|AAM21506.1| PrpC2 [Corynebacterium glutamicum]
sp|Q8NSL1|PRPC2_CORGL 2-methylcitrate synthase 2 (Methylcitrate synthase 2) (Citrate synthase 2)
ref|NP_599891.1| citrate synthase [Corynebacterium glutamicum ATCC 13032]
(383 aa)

Score: 77 bits (189), Expect: 7.85117e-13
Length: 336, Idn/Pos/Gap = 88/147/42 (26%/43%/12%)

Query: 127 EGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLL 186
           E + +LL  GE+PT  Q+    +  +   ++   ++ L+  LP E  HPM     AVS +
Sbjct:  50 EEVFYLLWHGELPTAQQLAEFNERGRSYRSLDAGLISLIHSLPKE-AHPMDVMRTAVSYM 108

Query: 187 QHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRN-------TFHGGKHVP 239
              +K +E +      +T  E+  +   TL+A+LP V A   R             K V 
Sbjct: 109 G--TKDSEYF------TTDSEHIRKVGHTLLAQLPMVLAMDIRRRKGLDIIAPDSSKSVA 160

Query: 240 AEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPY 299
              +  V   G     S   ++ +F++     L+L+A+H   N S    R++ S  SD Y
Sbjct: 161 ENLLSMVFGTGPESPASNPADVRDFEK----SLILYAEHSF-NASTFTARVITSTKSDVY 215

Query: 300 LSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGF 359
            +    +  L GPLHG AN+ V+  +L + +   N+     N        L   +V+ GF
Sbjct: 216 SAITGAIGALKGPLHGGANEFVMHTMLAIDDP--NKAAAWIN------NALDNKNVVMGF 267

Query: 360 GHAVLRRTDPRYTAQ----REFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNV 415
           GH V +R D R  +     RE A +H     +      +YE +   ++ +  +K   PN+
Sbjct: 268 GHRVYKRGDSRVPSMEKSFRELAARHDGEKWV-----AMYENMRDAMDARTGIK---PNL 319

Query: 416 DQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLV 451
           D  +G      G    +F+T LF ++R  G  + +V
Sbjct: 320 DFPAGPAYHLLGF-PVDFFTPLFVIARVAGWTAHIV 354


gb|AAO11076.1| Citrate synthase [Vibrio vulnificus CMCP6]
ref|NP_761549.1| Citrate synthase [Vibrio vulnificus CMCP6]
(380 aa)

Score: 77 bits (189), Expect: 8.32338e-13
Length: 332, Idn/Pos/Gap = 85/139/32 (25%/41%/9%)

Query: 127 EGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLL 186
           E + +LLL G +PT+ ++++    L     +P E+ + L+ +P    HPM       S+L
Sbjct:  53 EEVAYLLLRGHLPTQQELDAYKTRLIGLRGLPVELKQALELIP-ASAHPMDVMRTGCSVL 111

Query: 187 QHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKV 246
            +  +  +   Q           L+    ++A  PA+    YR + H G  +  +   + 
Sbjct: 112 GNLEQETDFSQQ-----------LDATERMLALFPAIICYWYRFS-HDGVRIDTQDQSQD 159

Query: 247 DDMGMRLARSLGFELNEF-DELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAG 305
              G  L    G E +E   ++M   L+L+A+HE  N S  A R+  S LSD +    A 
Sbjct: 160 CIGGYFLKMLTGKEPSELHKQVMHCSLILYAEHEF-NASTFAARVCASTLSDIHSCVTAA 218

Query: 306 LNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLR 365
           +  L GPLHG AN+  +  +   +        T E         L     I GFGHA+ R
Sbjct: 219 IGTLRGPLHGGANEAAMEMIENWQ--------TPEEAESNILRMLANKEKIMGFGHAIYR 270

Query: 366 RTDPRYTAQREF--ALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILL 423
            +DPR    + +  AL     D      + LY V  RV     + K+ + N D       
Sbjct: 271 ESDPRNALIKRWSKALSEAVGD------THLYAVSERVEAVMKREKDLFCNADFFHASAY 324

Query: 424 RYYGLVESNFYTVLFGVSRALGTLSSLVWDRA 455
            +   + +  +T +F +SR  G  + +   RA
Sbjct: 325 HFMD-IPTKLFTPIFVMSRLTGWTAHVFEQRA 355


ref|YP_224987.1| (METHYL)CITRATE SYNTHASE [Corynebacterium glutamicum ATCC 13032]
emb|CAF19401.1| (METHYL)CITRATE SYNTHASE [Corynebacterium glutamicum ATCC 13032]
gb|AAM21502.1| PrpC1 [Corynebacterium glutamicum]
sp|Q8NSH7|PRPC1_CORGL 2-methylcitrate synthase 1 (Methylcitrate synthase 1) (Citrate synthase 1)
ref|NP_599928.1| citrate synthase [Corynebacterium glutamicum ATCC 13032]
(381 aa)

Score: 76 bits (187), Expect: 1.37315e-12
Length: 331, Idn/Pos/Gap = 85/143/32 (25%/43%/9%)

Query: 127 EGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLL 186
           E +++LL  GE+PT  Q+ +     +   ++   ++ L+  LP+   HPM     AVS +
Sbjct:  47 EEVIYLLWFGELPTTEQLRTFNTTGRSYRSLDAGLISLIHSLPNT-CHPMDVLRTAVSYM 105

Query: 187 QHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEK- 245
                         P +   ++       L+A+LP V A   R     G+ + A    K 
Sbjct: 106 --------GTFDPDPFTRDADHIRSIGHNLLAQLPMVVAMDIRR--RSGEEIIAPDHNKG 155

Query: 246 --VDDMGMRLARSLGFELNEFDEL--MRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLS 301
              + + M      G   N  D++      L+L+A+H   N S  + R++ S  SD Y +
Sbjct: 156 IASNFLSMVFGNDDGSVANSADDIRDFERSLILYAEHSF-NASTFSARVISSTRSDTYSA 214

Query: 302 FAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGH 361
               +  L GPLHG AN+ V+  +L + +          N  +   + L     I GFGH
Sbjct: 215 ITGAIGALKGPLHGGANEFVMHTMLDIDDP--------NNAADWMGKALDRKERIMGFGH 266

Query: 362 AVLRRTDPRYTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGI 421
            V +  D R  +  E +++ L      Q    +YE +  V+E +  +K   PN+D  +G 
Sbjct: 267 RVYKNGDSRVPSM-EKSMRSLAARHRGQKWVHMYESMQEVMEARTGIK---PNLDFPAGP 322

Query: 422 LLRYYGL-VESNFYTVLFGVSRALGTLSSLV 451
              YY L    +F+T LF ++R  G  + +V
Sbjct: 323 --AYYMLGFPVDFFTPLFVLARVSGWTAHIV 351


gb|AAP76995.1| citrate synthase PrpC [Helicobacter hepaticus ATCC 51449]
ref|NP_859929.1| citrate synthase PrpC [Helicobacter hepaticus ATCC 51449]
(382 aa)

Score: 76 bits (187), Expect: 1.45574e-12
Length: 394, Idn/Pos/Gap = 91/166/37 (23%/42%/9%)

Query:  75 NQAYGGMRSLKAMVYETSLLDPQEGIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLL 134
           N   GG+  + A       +    G+ +RG+ I +  R          +   E + +LLL
Sbjct:   7 NTKVGGLAGITAGQSAICTVGTGHGLNYRGYDIYDLAR----------ECEFEEVAYLLL  56

Query: 135 TGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQ-HESKMA 193
             ++P  +++ +  ++L     +P  +   L  LP +  HPM       S+L   E +  
Sbjct:  57 KEKLPNANELAAFKKELIAARDLPKALKDTLKLLP-KNAHPMDIMRTTCSMLGCLEPETY 115

Query: 194 EAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRL 253
           +      P         + A+ L+   P+ A   + +  H GK +  +  +  D +    
Sbjct: 116 DIVKMSFPMQN------QIAIRLLGIFPS-ALTFWHHYHHNGKEISTQSNQ--DSIAGHF 166

Query: 254 ARSLGFELNE--FDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAG 311
              L  +  +  + + M   L+L+A+HE  N S    R++ + +SD Y      +  L G
Sbjct: 167 LELLHQKPPKELWIKAMHASLILYAEHEF-NASTFTARVITATMSDVYSGVTGAIGALRG 225

Query: 312 PLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRY 371
           PLHG AN+  +  + + K        T +   +   + L     I GFGH V  + DPR 
Sbjct: 226 PLHGGANEAAMELIAEYK--------TPQEAEKGILDKLARKDKIMGFGHRVYVKADPRN 277

Query: 372 TAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVES 431
              +E++ K        + +  + E + +V+ EQ K+   +PN+D +S     + G + +
Sbjct: 278 VVIKEWSKKLSEDVGDTKGLYPISEAIEKVMWEQKKL---FPNLDFYSASAYHFMG-IPT 333

Query: 432 NFYTVLFGVSRALGTLSSLVWDRALGLPIERPKS 465
            ++T +F  SR  G L+ +   RA    I RP S
Sbjct: 334 PYFTPIFIFSRTAGWLAHIFEQRANNKLI-RPSS 366


dbj|BAB98089.1| Citrate synthase [Corynebacterium glutamicum ATCC 13032]
(394 aa)

Score: 76 bits (187), Expect: 1.58242e-12
Length: 331, Idn/Pos/Gap = 85/143/32 (25%/43%/9%)

Query: 127 EGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLL 186
           E +++LL  GE+PT  Q+ +     +   ++   ++ L+  LP+   HPM     AVS +
Sbjct:  60 EEVIYLLWFGELPTTEQLRTFNTTGRSYRSLDAGLISLIHSLPNT-CHPMDVLRTAVSYM 118

Query: 187 QHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEK- 245
                         P +   ++       L+A+LP V A   R     G+ + A    K 
Sbjct: 119 --------GTFDPDPFTRDADHIRSIGHNLLAQLPMVVAMDIRR--RSGEEIIAPDHNKG 168

Query: 246 --VDDMGMRLARSLGFELNEFDEL--MRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLS 301
              + + M      G   N  D++      L+L+A+H   N S  + R++ S  SD Y +
Sbjct: 169 IASNFLSMVFGNDDGSVANSADDIRDFERSLILYAEHSF-NASTFSARVISSTRSDTYSA 227

Query: 302 FAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGH 361
               +  L GPLHG AN+ V+  +L + +          N  +   + L     I GFGH
Sbjct: 228 ITGAIGALKGPLHGGANEFVMHTMLDIDDP--------NNAADWMGKALDRKERIMGFGH 279

Query: 362 AVLRRTDPRYTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGI 421
            V +  D R  +  E +++ L      Q    +YE +  V+E +  +K   PN+D  +G 
Sbjct: 280 RVYKNGDSRVPSM-EKSMRSLAARHRGQKWVHMYESMQEVMEARTGIK---PNLDFPAGP 335

Query: 422 LLRYYGL-VESNFYTVLFGVSRALGTLSSLV 451
              YY L    +F+T LF ++R  G  + +V
Sbjct: 336 --AYYMLGFPVDFFTPLFVLARVSGWTAHIV 364


gb|AAN05014.1| citrate synthase [Rickettsia sp. DmS1]
(252 aa)

Score: 76 bits (186), Expect: 1.77849e-12
Length: 236, Idn/Pos/Gap = 63/117/20 (26%/49%/8%)

Query: 213 ALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDD-MGMRLARS-LGFELNEF--DELM 268
           A+ +IA +P +AA  Y+ +       P   ++   + + M  A     +++N    + L 
Sbjct:  28 AIRMIAEIPTIAAMSYKYSIGQPFIYPDNSLDFTKNFLHMMFAMPCTKYKVNPIIKNALN  87

Query: 269 RLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQM 328
           +++ +LHADHE  N S   VR+ GS+ ++P+   + G+  L GP HG AN+ V    + M
Sbjct:  88 KIF-ILHADHEQ-NASTSTVRIAGSSGANPFACISTGIASLWGPAHGGANEAV----INM 141

Query: 329 KEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFA-----LKHLP 383
            +++G+     + + +   +   +   + GFGH V +  DPR    +E       L  L 
Sbjct: 142 LKEIGSSEYIPKYIAKA--KDKNDPFRLMGFGHRVYKNYDPRTAVLKEMCKVLKELGQLD 199

Query: 384 HDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFG 439
           ++ + Q+  +L  +  +  +E    +  +PNVD +SGI+ +  G + S  +TVLF 
Sbjct: 200 NNPLLQIAIELEAIALK--DEYFIERKLYPNVDFYSGIIYKAMG-IPSQMFTVLFA 252


gb|AAN05015.1| citrate synthase [Rickettsia slovaca]
(253 aa)

Score: 76 bits (186), Expect: 1.83885e-12
Length: 237, Idn/Pos/Gap = 63/118/21 (26%/49%/8%)

Query: 213 ALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDD-MGMRLARS-LGFELNEF--DELM 268
           A+ +IA++P +AA  Y+ +       P   ++  ++ + M  A     + +N    + L 
Sbjct:  28 AIRMIAKIPTIAAMSYKYSIGQPFIYPDNSLDFTENFLHMMFATPCTKYTVNPIIKNALN  87

Query: 269 RLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQM 328
           +++ +LHADHE  N S   VR+ GS+ ++P+   + G+  L GP HG AN+ V    + M
Sbjct:  88 KIF-ILHADHEQ-NASTSTVRIAGSSGANPFACISTGIASLWGPAHGGANEAV----INM 141

Query: 329 KEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFA------LKHL 382
            +++G+     + + +   +   +   + GFGH V +  DPR    +E        L  L
Sbjct: 142 LKEIGSSEYIPKYIAKA--KDKNDPFRLMGFGHRVYKNYDPRAAVLKETCKEVLKELGQL 199

Query: 383 PHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFG 439
            ++ + Q+  +L  +  +  +E    +  +PNVD +SGI+ +  G + S  +TVLF 
Sbjct: 200 DNNPLLQIAIELEAIALK--DEYFIERKLYPNVDFYSGIIYKAMG-IPSQMFTVLFA 253


emb|CAA93844.1| citrate synthase [Bartonella sp.]
(319 aa)

Score: 76 bits (186), Expect: 2.04953e-12
Length: 306, Idn/Pos/Gap = 81/141/27 (26%/46%/8%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LLL GE+PT+ +     + + +   V  +  R       +  HPM   +V V+ L   S
Sbjct:  32 YLLLYGELPTKQEKNDFDRCIMQHTMVHEQFARFFHGFRRDS-HPM---AVMVACLGAMS  87

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMG 250
               A+   +   T  +  +  ++ LI+++P +AA  Y+ +       P   +    +  
Sbjct:  88 ----AFYHDSIDITDPQQRMIASVRLISKVPTLAAMAYKYSIGQAFVYPRNDLSYAANF- 142

Query: 251 MRLARSLGFELNEFDEL----MRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGL 306
           +R+  S+  E  + + +    M    +LHADHE  N S   VRL GS+ ++P+   AAG+
Sbjct: 143 LRMCFSVPCEEYKTNPVLTRAMDRIFILHADHEQ-NASTSTVRLAGSSGANPFACIAAGV 201

Query: 307 NGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRR 366
             L GP HG AN+  L+    M +++G+     E +     +   +   + GFGH V + 
Sbjct: 202 ACLWGPAHGGANEACLK----MLQEIGDVKRIPEFIARA--KDRNDPFRLMGFGHRVYKN 255

Query: 367 TDPRYTAQREF---ALKHL--PHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGI 421
            DPR    ++     LK L    D +  +  +L ++   + +E    K  +PNVD +SGI
Sbjct: 256 YDPRAKIMQKTCHEVLKELNIQDDPLLDIAIELEKIA--LNDEYFVEKKLYPNVDFYSGI 313

Query: 422 LLRYYG 427
            L+  G
Sbjct: 314 TLKALG 319


gb|AAG59872.1| citrate synthase [Ehrlichia sp. ERm58]
(380 aa)

Score: 76 bits (186), Expect: 2.1728e-12
Length: 381, Idn/Pos/Gap = 97/166/54 (25%/43%/14%)

Query:  80 GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEI 138
           G  S  A     + +D  +GI R+RG++I +   L+   K   E      +++LL  G +
Sbjct:  18 GFMSTAACESRITFIDGNKGILRYRGYNIAD---LVNSNKSFIE------IVYLLFYGVL  68

Query: 139 PTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQ 198
           P  + +++    + +       V  ++   P    HPM   ++ +S     S +A  Y  
Sbjct:  69 PDANDLQNFVLQVSQEYMPIKIVNDIIKSFPRNS-HPM---AILISCF---SGLASYYNN 121

Query: 199 GAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLG 258
                   +Y    A   ++++  + A IYR       H+  +   + +     L+ S  
Sbjct: 122 QRHNEDELKY----ARLAVSQIAGIVAMIYR-------HITDQDFIQAN---TELSYSEN 167

Query: 259 FELNEFD-----------ELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLN 307
           F    FD           + + +  +LHADHE  N S   VRL GS  ++ +   AAG  
Sbjct: 168 FIHMMFDISSYEFTKVVSKALDVIFILHADHEQ-NASTATVRLTGSTGANLFACLAAGAA 226

Query: 308 GLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRT 367
            L GP HG AN+ V+  L+++ EK  N     + +++        G  + GFGH V +  
Sbjct: 227 TLWGPAHGGANEAVINMLMEI-EKPSNVKQFVQKVKD-----KNNGIRLMGFGHRVYKNY 280

Query: 368 DPRYTAQREFALKHLPHD--EMFQLVSKLYEVVPRVLEEQGKV-KNPWPNVDQHSGILLR 424
           DPR     E   K + +D      L+    E+    L++   + ++ +PNVD +SGI+L+
Sbjct: 281 DPRAKIICEIC-KEVLNDLKTSHPLLEVALELESIALQDSYFIERSLYPNVDFYSGIVLK 339

Query: 425 YYGLVESNFYTVLFGVSRALG 445
             G+  S F T LF ++R  G
Sbjct: 340 AIGIPVSMF-TTLFALARTSG 359


ref|YP_090611.1| CitA [Bacillus licheniformis ATCC 14580]
gb|AAU39918.1| CitA [Bacillus licheniformis DSM 13]
(363 aa)

Score: 76 bits (186), Expect: 2.20936e-12
Length: 381, Idn/Pos/Gap = 93/157/61 (24%/41%/16%)

Query:  78 YGGMRSLKAMVYETSLLDPQEG-IRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTG 136
           Y G++ +  +    S +D ++G + +RG++  E                 E + +L+L G
Sbjct:   3 YHGLKGITCVETAISRIDGEKGKLIYRGYNADEL----------ALSSTFEEVAYLILNG  52

Query: 137 EIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAY 196
             PTE+++    + L     +P    RL+  LP E +  M     AVS            
Sbjct:  53 AFPTEAELSRFNELLASFRVLPEACERLIRSLPAE-LDDMAVLRTAVSSF---------- 101

Query: 197 AQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARS 256
                 S  ++  +E AL LIA +P++ A  +R     G+    E ++ +D+        
Sbjct: 102 ---GDISFAFKPTMEQALRLIAAVPSIIA--FRKRLADGE----EPVQPLDE-------- 144

Query: 257 LGFELNEFDEL------------MRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAA 304
           LGF  N F  L            +  Y++L  +H G N S  + R+  S  SD   +  +
Sbjct: 145 LGFVENYFYMLKGKRPTEAQKKALETYMILAMEH-GMNASTFSARVTVSTESDLVSAVTS 203

Query: 305 GLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVL 364
            L  + GPLHG A   V      M E +G +      +RE     L +G  + GFGH V 
Sbjct: 204 ALGTMKGPLHGGAPSAVT----DMLEGIGEKQHAESYIRE----KLEKGERLMGFGHRVY 255

Query: 365 RRTDPRYTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLR 424
           +  DPR  A R  A +    D    L   +     R+LEE    +  + NV+ ++  +++
Sbjct: 256 KTHDPRAKALRVKAEEIAGGDRDIDLALHVENTAIRLLEEYKPGRKLYTNVEFYAAAVMK 315

Query: 425 YYGLVESNFYTVLFGVSRALG 445
                ++  +T  F  +R +G
Sbjct: 316 AIDF-DAALFTPTFSAARMVG 335


ref|NP_934323.1| citrate synthase [Vibrio vulnificus YJ016]
dbj|BAC94294.1| citrate synthase [Vibrio vulnificus YJ016]
(401 aa)

Score: 75 bits (185), Expect: 2.90969e-12
Length: 327, Idn/Pos/Gap = 84/136/32 (25%/41%/9%)

Query: 132 LLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESK 191
           LLL G +PT+ ++++    L     +P E+ + L+ +P    HPM       S+L +  +
Sbjct:  79 LLLRGHLPTQQELDAYKTRLIGLRGLPAELKQALELIP-ASAHPMDVMRTGCSVLGNLEQ 137

Query: 192 MAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGM 251
             +   Q           L+    ++A  PA+    YR + H G  +  +   +    G 
Sbjct: 138 ETDFSQQ-----------LDATERMLALFPAIICYWYRFS-HDGVRINTQDQSQDCIGGY 185

Query: 252 RLARSLGFELNEF-DELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLA 310
            L    G E +E   ++M   L+L+A+HE  N S  A R+  S LSD +    A +  L 
Sbjct: 186 FLKMLTGKEPSELHKQVMHCSLILYAEHEF-NASTFAARVCASTLSDIHSCVTAAIGTLR 244

Query: 311 GPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPR 370
           GPLHG AN+  +  +   +        T E         L     I GFGHA+ R +DPR
Sbjct: 245 GPLHGGANEAAMEMIENWQ--------TPEEAESNILRMLANKEKIMGFGHAIYRESDPR 296

Query: 371 YTAQREF--ALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGL 428
               + +  AL     D      + LY V  RV     + K+ + N D        +   
Sbjct: 297 NALIKRWSKALSEAVGD------THLYAVSERVEAVMKREKDLFCNADFFHASAYHFMD- 349

Query: 429 VESNFYTVLFGVSRALGTLSSLVWDRA 455
           + +  +T +F +SR  G  + +   RA
Sbjct: 350 IPTKLFTPIFVMSRLTGWTAHVFEQRA 376


ref|YP_208573.1| putative citrate synthase [Neisseria gonorrhoeae FA 1090]
gb|AAW90161.1| putative citrate synthase [Neisseria gonorrhoeae FA 1090]
(382 aa)

Score: 75 bits (185), Expect: 2.95865e-12
Length: 337, Idn/Pos/Gap = 88/148/33 (26%/43%/9%)

Query: 132 LLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESK 191
           LL+ G +P + ++ +    LK    +P  V+++L+ LP    HPM      VS+L     
Sbjct:  60 LLIHGHLPNKFELAAYKTKLKSMRGLPIRVIKVLESLP-AHTHPMDVMRTGVSMLGCVHP 118

Query: 192 MAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGM 251
             E++     +          A  LIA L ++    Y+ + H GK +  E  E+    G 
Sbjct: 119 ERESHPDSEARDI--------ADKLIASLGSILLYWYQYS-HNGKRIEVESDEETVG-GH 168

Query: 252 RLARSLGFELNEFD-ELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLA 310
            L    G   +E   + M + L+L+A+HE  N S    R++    SD Y      +  L 
Sbjct: 169 FLHLLHGKRPSESHIKAMHVSLILYAEHEF-NASTFTARVIAGTGSDMYSCITGAIGALK 227

Query: 311 GPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPR 370
           GP HG AN+  + + +Q +     R     ++R    E +    ++ GFGH V   +DPR
Sbjct: 228 GPKHGGANE--VAYDIQKRY----RNADEADIR----ERIGRKEIVIGFGHPVYTISDPR 277

Query: 371 YTAQREFA--LKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGL 428
               +E A  L     D       +L+++  R+     + K  +PN+D  S +  +  G 
Sbjct: 278 NVVIKEVARGLSREAGD------MRLFDIAERLESVMWEEKKMFPNLDWFSAVSYQKLG- 330

Query: 429 VESNFYTVLFGVSRALGTLSSLVWDRALGLPIERPKS 465
           V +  +T LF +SR+ G  + ++  R  G  I RP +
Sbjct: 331 VPTAMFTPLFVISRSTGWAAHVLEQRKDG-KIIRPSA 366


emb|CAA93837.1| citrate synthase [Bartonella vinsonii]
sp|P51036|CISY_BARVI Citrate synthase
(319 aa)

Score: 75 bits (184), Expect: 3.03365e-12
Length: 307, Idn/Pos/Gap = 81/141/27 (26%/45%/8%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LLL GE+PT+ +     + + +   V  +  R       +  HPM   +V V+ L   S
Sbjct:  28 YLLLYGELPTQQEKSDFDRCIMQHTMVHEQFARFFHGFRRDS-HPM---AVMVACLGAMS  83

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMG 250
               A+   +   T  +  +  ++ LI+++P +AA  Y+ +       P   +    +  
Sbjct:  84 ----AFYHDSIDITDPQQRMIASVRLISKVPTLAAMAYKYSIGQAFVYPRNDLSYAANF- 138

Query: 251 MRLARSLGFELNEFDEL----MRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGL 306
           +R+  S+  E  + + +    M    +LHADHE  N S   VRL GS+ ++P+   AAG+
Sbjct: 139 LRMCFSVPCEEYKTNPVLTRAMDRIFILHADHEQ-NASTSTVRLAGSSGANPFACIAAGV 197

Query: 307 NGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRR 366
             L GP HG AN+  L+    M +++G+     E +     +   +   + GFGH V + 
Sbjct: 198 ACLWGPAHGGANEACLK----MLQEIGSVKRIPEFIARA--KDKNDPFRLMGFGHRVYKN 251

Query: 367 TDPRYTAQREF---ALKHL--PHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGI 421
            DPR    ++     LK L    D +  +  +L ++   + +E    K  +PNVD +SGI
Sbjct: 252 YDPRAKIMQKTCHEVLKELNIQDDPLLDIAIELEKIA--LNDEYFVEKKLYPNVDFYSGI 309

Query: 422 LLRYYGL 428
            L+  G 
Sbjct: 310 TLKALGF 316


ref|ZP_00367535.1| 2-methylcitrate synthase [Campylobacter coli RM2228]
gb|EAL56883.1| 2-methylcitrate synthase [Campylobacter coli RM2228]
(375 aa)

Score: 75 bits (184), Expect: 3.05906e-12
Length: 369, Idn/Pos/Gap = 92/163/42 (24%/44%/11%)

Query:  99 GIRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVP 158
           G+ + G+SI E            +    E + +LL  GE+P   ++E+  + +  + A+ 
Sbjct:  31 GLNYYGYSIEEL----------AQNAEFEEIAYLLQFGELPNAKELENYKEKIIAQRALS  80

Query: 159 PEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIA 218
             +  +L  +P E +HPM     AV+ L       E ++             E  + L+ 
Sbjct:  81 ENLKNVLKAIPKE-VHPMNLMQTAVAALGALEGENEDFSDQD----------EKIIRLLG 129

Query: 219 RLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLAR-SLGFELNEFDELMRLYLVLHAD 277
            LP++    + +  + GK +  +   +    G  L +  L     +F + M+  L+L+A+
Sbjct: 130 ILPSMLC-YWHHYVNFGKEIDFDS-NQTSIAGYFLEKLKLEAPKEDFIKAMQCSLILYAE 187

Query: 278 HEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPM 337
           HE  N S    R+  S  SD + + AA +  L GPLHG AN+  +  +   K        
Sbjct: 188 HEF-NASTFTARICASTKSDIFSAVAAAIGALRGPLHGGANEAAMHLIESFK-------- 238

Query: 338 TTENLRELCWETLREGHVIPGFGHAVL-RRTDPRYTAQREFALKHLPHDEMFQLVSKLYE 396
           + E+  E   + L    ++ GFGH V     DPR    + ++ KHL  D+   L+ K+ E
Sbjct: 239 SVEDAIEGVNKKLENKELLMGFGHRVYGLGGDPRNALIKVWS-KHLGGDD---LLFKISE 294

Query: 397 VVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRAL 456
            +  +++E  K  +  PN D +S     + G + + ++T +F +SR  G  + +   RA 
Sbjct: 295 AIEALMKE--KRPSLPPNADFYSASAYHFMG-IPTEYFTPIFIMSRVSGWCAHIKEQRAN 351

Query: 457 GLPIERPKS 465
              I RP S
Sbjct: 352 NKLI-RPSS 359


emb|CAA93839.1| citrate synthase [Bartonella doshiae]
sp|Q59198|CISY_BARDO Citrate synthase
(320 aa)

Score: 75 bits (184), Expect: 3.11054e-12
Length: 307, Idn/Pos/Gap = 80/140/27 (26%/45%/8%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LLL GE+PT+ +     + + +   V  +  R       +  HPM   +V V+ L   S
Sbjct:  31 YLLLYGELPTQQEKNDFDRRIMQHTMVHEQFSRFFQGFRRDS-HPM---AVMVACLGAMS  86

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMG 250
               A+   +   T  +  +  ++ LI+++P +AA  Y+ +       P   +    +  
Sbjct:  87 ----AFYHDSIDITDPQQRMIASIRLISKVPTLAAMAYKYSIGQAFVYPHNSLSYAANF- 141

Query: 251 MRLARSLGFELNEFDEL----MRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGL 306
           +R+  ++  E  + + +    M    +LHADHE  N S   VRL GS+ ++P+   AAG+
Sbjct: 142 LRMCFAVPCEEYQVNPVLTRAMDRIFILHADHEQ-NASTSTVRLAGSSGANPFACIAAGV 200

Query: 307 NGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRR 366
             L GP HG AN+  L+    M +++G+     E +     +   +   + GFGH V + 
Sbjct: 201 ACLWGPAHGGANEACLK----MLKEIGSVKKIPEFIARA--KDKNDPFRLMGFGHRVYKN 254

Query: 367 TDPRYTAQREF---ALKHLPH--DEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGI 421
            DPR    ++     LK L    D +  +  +L  +   + +E    K  +PNVD +SGI
Sbjct: 255 YDPRAKIMQKTCHEVLKELNRQDDPLLDIAIELEHIA--LNDEYFIEKKLYPNVDFYSGI 312

Query: 422 LLRYYGL 428
            L+  G 
Sbjct: 313 TLKALGF 319


gb|AAK52340.1| 2-methylcitrate synthase [Burkholderia sacchari]
(388 aa)

Score: 75 bits (184), Expect: 3.1366e-12
Length: 330, Idn/Pos/Gap = 85/147/28 (25%/44%/8%)

Query: 127 EGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLL 186
           E + +LL+ G++P  +++ +    LK    +P  V   L+ +P    HPM      VS+L
Sbjct:  59 EEVAYLLVHGKLPNIAELAAYKTKLKALRGLPANVKAALEWVP-ASAHPMDVMRTGVSVL 117

Query: 187 QHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKV 246
              + + E      P +       + A  L+A L ++    Y N+ H GK +  E  +  
Sbjct: 118 G--TVLPEKDDHNLPGAR------DIADRLMASLGSMLLYWYHNS-HNGKRIEVETDD-- 166

Query: 247 DDMGMRLARSL-GFELNE-FDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAA 304
           D +G      L G E ++ + + M + L L+A+HE  N S    R++    SD Y +   
Sbjct: 167 DSIGGHFLHLLHGREPSKSWVDAMHVSLNLYAEHEF-NASTFTGRVIAGTGSDMYSAITG 225

Query: 305 GLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVL 364
            +  L GP HG AN+       +++ +         ++R      +    V+ GFGH V 
Sbjct: 226 AIGALRGPKHGGANEVA----FEIQSRYDTPDQAESDIR----RRVEAKAVVIGFGHPVY 277

Query: 365 RRTDPRYTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLR 424
             +DPR    +E A K L  +   Q   KL+++  R+     ++K  +PN+D  S +   
Sbjct: 278 TISDPRNKVIKEVA-KKLSKE---QSNLKLFDIAERLESTMWEIKKMFPNLDWFSAVSYH 333

Query: 425 YYGLVESNFYTVLFGVSRALGTLSSLVWDR 454
             G V +  +T LF +SR  G  + ++  R
Sbjct: 334 MMG-VPTAMFTPLFVISRTAGWSAHIIEQR 362


emb|CAA93841.1| citrate synthase [Bartonella sp.]
(315 aa)

Score: 75 bits (184), Expect: 3.35312e-12
Length: 306, Idn/Pos/Gap = 81/141/27 (26%/46%/8%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LLL GE+PT+ +     + + +   V  +  R       +  HPM   +V V+ L   S
Sbjct:  28 YLLLYGELPTKQEKNDFDRCIMQHTMVHEQFARFFHGFRRDS-HPM---AVMVACLGAMS  83

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMG 250
               A+   +   T  +  +  ++ LI+++P +AA  Y+ +       P   +    +  
Sbjct:  84 ----AFYHDSIDITDPQQRMIASVRLISKVPTLAAMAYKYSIGQAFVYPRNDLSYAANF- 138

Query: 251 MRLARSLGFELNEFDEL----MRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGL 306
           +R+  S+  E  + + +    M    +LHADHE  N S   VRL GS+ ++P+   AAG+
Sbjct: 139 LRMCFSVPCEEYKTNPVLTRAMDRIFILHADHEQ-NASTSTVRLAGSSGANPFACIAAGV 197

Query: 307 NGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRR 366
             L GP HG AN+  L+    M +++G+     E +     +   +   + GFGH V + 
Sbjct: 198 ACLWGPAHGGANEACLK----MLQEIGSVKRIPEFIARA--KDRNDPFRLMGFGHRVYKN 251

Query: 367 TDPRYTAQREF---ALKHL--PHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGI 421
            DPR    ++     LK L    D +  +  +L ++   + +E    K  +PNVD +SGI
Sbjct: 252 YDPRAKIMQKTCHEVLKELNIQDDPLLDIAIELEKIA--LNDEYFVEKKLYPNVDFYSGI 309

Query: 422 LLRYYG 427
            L+  G
Sbjct: 310 TLKALG 315


gb|AAO48736.1| citrate synthase [Rickettsia sp. RDla440]
(369 aa)

Score: 75 bits (184), Expect: 3.46691e-12
Length: 388, Idn/Pos/Gap = 90/168/62 (23%/43%/15%)

Query:  60 VRERFGEEVLDACTVNQAYG------GMRSLKAMVYETSLLDPQEGI-RFRGFSIPECQR 112
           ++   GE+V+D   V+          G  S  +     + +D  +GI R RG+ I     
Sbjct:  19 LKASIGEDVIDISRVSAEADCFTYDPGFMSTASCQSTITYIDGDKGILRHRGYDI-----  73

Query: 113 LLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHER 172
                K   E+     + +LL+ GE+P+  Q  +  + +   + V            +ER
Sbjct:  74 -----KDLAEKSDFLEVAYLLIYGELPSGEQYNNFTKQVAHHSLV------------NER 116

Query: 173 MHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLE--------DALTLIARLPAVA 224
           +H + Q     +       MA   A     S F+   L          A+ +IA++P +A
Sbjct: 117 LHYLFQ-----TFCSSSHPMAIMLAAVGSLSAFYPDLLNFKEADYELTAIRMIAKIPTIA 171

Query: 225 ARIYRNTFHGGKHVPAEKIEKVDD-MGMRLARS-LGFELNEF--DELMRLYLVLHADHEG 280
           A  Y+ +       P   ++  ++ + M  A     +++N    + L +++ +LHADHE 
Sbjct: 172 AMSYKYSIGQPFIYPDNSLDFTENFLHMMFATPCTKYKVNPIIKNALNKIF-ILHADHEQ 230

Query: 281 GNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTE 340
            N S   VR+ GS+ ++P+   + G+  L GP HG AN+ V    + M +++G+     +
Sbjct: 231 -NASTSTVRIAGSSGANPFACISTGIASLWGPAHGGANEAV----INMLKEIGSFEYIPK 285

Query: 341 NLRELCWETLREGHVIPGFGHAVLRRTDPRYTAQREFA------LKHLPHDEMFQLVSKL 394
            + +   +   +   + GFGH V +  DPR    +E        L  L ++ + Q+  +L
Sbjct: 286 YIAKA--KDKNDPFRLMGFGHRVYKNYDPRAAVLKETCKEVLKELGQLDNNPLLQIAIEL 343

Query: 395 YEVVPRVLEEQGKVKNPWPNVDQHSGIL 422
             +  +  +E    +  +PNVD +SGI+
Sbjct: 344 EAIALK--DEYFIERKLYPNVDFYSGII 369


ref|ZP_00372394.1| citrate synthase [Wolbachia endosymbiont of Drosophila simulans]
gb|EAL60091.1| citrate synthase [Wolbachia endosymbiont of Drosophila simulans]
(362 aa)

Score: 75 bits (184), Expect: 3.46691e-12
Length: 314, Idn/Pos/Gap = 79/148/34 (25%/47%/10%)

Query:  92 SLLDPQEGI-RFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQD 150
           + +D  EG+ ++RG +I +            E      +++LLL GE+P+  Q +     
Sbjct:  58 TFIDGDEGVLKYRGHNIADL----------AENNNFTAVIYLLLYGELPSSEQHKKFLLK 107

Query: 151 LKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCL 210
           ++  + V  +V  ++   P +  HPM   S+ V+     + ++ +Y +    +   E  L
Sbjct: 108 IQESSKVSEQVTNVIKAFP-KTAHPM---SILVACF---ASLSASYHEKHGNNVNGED-L 159

Query: 211 EDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNE---FDEL 267
           +  ++ IA++  + A I R+  +  + + A       +  +++      + ++   F + 
Sbjct: 160 DFGISAIAQVSTIIAMICRHN-NNQEFINANNELSYSENFLKMIFGDAVDNDKSALFAKA 218

Query: 268 MRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQ 327
           +     LHADHE  N S  AVRLVGSA S+ + S +AG+  L GP HG AN+ V+  L +
Sbjct: 219 LDKIFTLHADHEQ-NASTAAVRLVGSAGSNLFASLSAGVATLWGPAHGGANEAVINMLKE 277

Query: 328 MKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRRTDPRYT----AQREFALKHLP 383
           + E+ G+     E  ++      ++   + GFGH V +  DPR      A  E   K   
Sbjct: 278 I-EQSGDIDKFIEKAKD-----DKDPFKLMGFGHRVYKNYDPRARILKGACHEVLSKLEQ 331

Query: 384 HDEMFQLVSKLYEV 397
           ++E+ ++  KL E+
Sbjct: 332 NNELLKIAKKLEEI 345


ref|ZP_00272783.1| COG0372: Citrate synthase [Ralstonia metallidurans CH34]
(399 aa)

Score: 75 bits (184), Expect: 3.7686e-12
Length: 330, Idn/Pos/Gap = 84/143/28 (25%/43%/8%)

Query: 127 EGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLL 186
           E +  LL+ G++PT+S++ +    LK    +P  V   L+ +P    HPM      VS+L
Sbjct:  69 EEIAHLLVHGKLPTKSELAAYKVKLKALRGLPANVKAALEWVP-ASAHPMDVMRTGVSVL 127

Query: 187 QHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKV 246
              + + E      P +       + A  L+A L ++    Y  + H G+ +  E  +  
Sbjct: 128 G--TVLPEKDDHNTPGAR------DIADRLMASLGSMLLYWYHYS-HNGRRIEVETDD-- 176

Query: 247 DDMGMRLARSLGFELNE--FDELMRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAA 304
           D +       L  E     ++  M+  L+L+A+HE  N S  A R+V    SD Y +   
Sbjct: 177 DSIAAHFLHLLHGEAPSKLWERAMQTSLILYAEHEF-NASTFACRVVAGTGSDMYSAICG 235

Query: 305 GLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVL 364
           G+  L GP HG AN+       +++++         ++R      +    V+ GFGH V 
Sbjct: 236 GIGALRGPKHGGANEVA----FEIQKRYDTPDEAEADIR----RRVENKEVVIGFGHPVY 287

Query: 365 RRTDPRYTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGILLR 424
             +DPR    +E A K L  D       K++ +  R+       K  +PN+D  S +   
Sbjct: 288 TISDPRNVVIKEVARK-LSKDAGSM---KMFNIAERLETVMADAKKMFPNLDWFSAVSYH 343

Query: 425 YYGLVESNFYTVLFGVSRALGTLSSLVWDR 454
             G V +  +T LF ++R  G  + ++  R
Sbjct: 344 MMG-VPTAMFTPLFVIARTSGWAAHVIEQR 372


emb|CAA93832.1| citrate synthase [Bartonella sp.]
(321 aa)

Score: 75 bits (184), Expect: 3.80017e-12
Length: 310, Idn/Pos/Gap = 82/137/33 (26%/44%/10%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSV---AVSLLQ 187
           +LLL GE+PT+ +     + + +   V  +  R       +  HPM        A+S L 
Sbjct:  30 YLLLYGELPTKQEKNDFDRCIMQHTMVHEQFARFFHGFRRDS-HPMAVMVACLGAMSALY  88

Query: 188 HESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVD 247
           H+S       Q    S          + LI+++P +AA  Y+ +       P   +    
Sbjct:  89 HDSIDITDPQQRMIAS----------VRLISKVPTLAAMAYKYSIGQAFIYPRNDLSYAA 138

Query: 248 DMGMRLARSLGFELNEFDEL----MRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFA 303
           +  +R+  S+  E  + + +    M    +LHADHE  N S   VRL GS+ ++P+   A
Sbjct: 139 NF-LRMCFSVPCEEYKTNPVLTRAMDRIFILHADHEQ-NASTSTVRLAGSSGANPFACIA 196

Query: 304 AGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAV 363
           AG+  L GP HG AN+  L+    M +++G+     E +     +   +   + GFGH V
Sbjct: 197 AGVACLWGPAHGGANEACLK----MLQEIGSVERIPEFIARA--KDKNDPFRLMGFGHRV 250

Query: 364 LRRTDPRYTAQREF---ALKHL--PHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQH 418
            +  DPR    ++     LK L    D +  +  +L ++   + +E    K  +PNVD +
Sbjct: 251 YKNYDPRAKIMQKTCHEVLKELNIQDDPLLDIAIELEKIA--LNDEYFVEKKLYPNVDFY 308

Query: 419 SGILLRYYGL 428
           SGI L+  G 
Sbjct: 309 SGITLKALGF 318


emb|CAD56502.1| citrate synthase 1 [Thermoproteus tenax]
(374 aa)

Score: 75 bits (183), Expect: 4.416e-12
Length: 358, Idn/Pos/Gap = 97/159/46 (27%/44%/12%)

Query: 100 IRFRGFSIPECQRLLPRAKPSGEQPLPEGLLWLLLTGEIPTESQVESVCQDLKRRAAVPP 159
           I +RG+ I E            ++   E   +LL+ G++P  S++++  + L      P 
Sbjct:  27 IYYRGYDIEEL----------ADKSTFEETAYLLIYGQLPRASELDAFKERLASLRRPPE  76

Query: 160 EVLRLLDELPHERMHPMTQFSVAVSLLQHESKMAEAYAQGAPKSTFWEYCLEDALTLIAR 219
            V++LL  LP +   P+     AVS +     M    +  +P++      LE  L +IA 
Sbjct:  77 HVVKLLGLLP-KSAEPIDVLRTAVSAM----GMGRNLSDRSPEAE-----LERGLEVIAS 126

Query: 220 LPAVAARIYRNTFHGGKHVPAEKIEKVDDMGMRLARSLGFELNEFDELMRLYLVLHADHE 279
           +P +AA   R     G  +   + E   +  +R  +  G       + M + L+++A+H 
Sbjct: 127 MPFIAANWDRT--RRGLEIADPQAEGHAEYFLRALK--GDASPRQIKAMDVMLIIYAEH- 181

Query: 280 GGNVSAHAVRLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTT 339
           G N SA     V S LSD Y   +A +  L GPLHG AN +  +    M E++G      
Sbjct: 182 GMNNSAFTAVTVASTLSDMYSVISAAIASLKGPLHGGANIDAAK----MIEEVG------ 231

Query: 340 ENLRELCW--ETLREGHVIPGFGHAVLRR-TDPRYTAQREFALKHLPHD---EMFQLVSK 393
           E  R   W  E L  G  IPGFGH + +R  DPR    R  A +        + +++  +
Sbjct: 232 EPGRVQRWVDEALAAGKRIPGFGHRLYKRGPDPRLRVLRRLARELAEEAGDYKYYEIAER 291

Query: 394 LYEVVPRVLEEQGKVKNPWPNVDQHSGILLRYYGLVESNFYTVLFGVSRALGTLSSLV 451
           L E V   L  +G     + N D ++ ++ +Y GL  ++     F +SRA G ++  V
Sbjct: 292 LEEYVHSRLSHKGI----YANTDLYAAVIFKYLGL-PTDLNLPAFAMSRAAGWVAHAV 344


sp|P51031|CISY_BARBA Citrate synthase
(321 aa)

Score: 75 bits (183), Expect: 4.60412e-12
Length: 307, Idn/Pos/Gap = 80/135/27 (26%/43%/8%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LLL GE+P + Q     + + R   V  +  R       +  HPM   +V V+ L   S
Sbjct:  30 YLLLYGELPNKQQKIDFDRCIMRHTMVHEQFARFFHGFRRDS-HPM---AVMVACLGAMS  85

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMG 250
               A+   +   T  +  +  ++ LI+++P +AA  Y+ +       P   +    +  
Sbjct:  86 ----AFYHDSINITDPQQRMIASIRLISKVPTLAAMAYKYSIGQPFVYPRNDLNYATNF- 140

Query: 251 MRLARSLGFELNEFDEL----MRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGL 306
           + +  S+  E ++   +    M     LHADHE  N S   VRL GS+ ++PY   AAG+
Sbjct: 141 LHMCFSVPCEEHKISPVIARAMDRIFTLHADHEQ-NASTSTVRLAGSSGANPYACIAAGV 199

Query: 307 NGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRR 366
             L GP HG AN+  L+    M +++G+     E +     +   +   + GFGH V + 
Sbjct: 200 ACLWGPAHGGANEACLK----MLQEIGSVKKIPEFIARA--KDKNDPFRLMGFGHRVYKN 253

Query: 367 TDPRY-----TAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGI 421
            DPR      T        ++  D +  +  +L  +   + +E    K  +PNVD +SGI
Sbjct: 254 YDPRAKIMQKTCHEVLQELNIQDDPLLDIAMELEHIA--LNDEYFINKKLYPNVDFYSGI 311

Query: 422 LLRYYGL 428
            L+  G 
Sbjct: 312 TLKALGF 318


gb|AAT37467.1| citrate synthase [Bartonella taylorii]
(330 aa)

Score: 74 bits (182), Expect: 5.17462e-12
Length: 307, Idn/Pos/Gap = 80/140/27 (26%/45%/8%)

Query: 131 WLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLLQHES 190
           +LLL GE+PT+ +     + + +   V  +  R       +  HPM   +V V+ L   S
Sbjct:  40 YLLLYGELPTQQEKHDFDRCIMQHTMVHEQFARFFHGFRRDS-HPM---AVMVACLGAMS  95

Query: 191 KMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKVDDMG 250
               A+   +   T  +  +  ++ LI+++P +AA  Y+ +       P   +    +  
Sbjct:  96 ----AFYHDSIDITDPQQRMIASVRLISKVPTLAAMAYKYSIGQAFVYPRNDLSYAANF- 150

Query: 251 MRLARSLGFELNEFDEL----MRLYLVLHADHEGGNVSAHAVRLVGSALSDPYLSFAAGL 306
           +R+   +  E  + + +    M    +LHADHE  N S   VRL GS+ ++P+   AAG+
Sbjct: 151 LRMCFCVPCEEYKINPVLTRAMDRIFILHADHEQ-NASTSTVRLAGSSGANPFACIAAGV 209

Query: 307 NGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPGFGHAVLRR 366
             L GP HG AN+  L+    M +++G+     E +     +   +   + GFGH V + 
Sbjct: 210 ACLWGPAHGGANEACLK----MLQEIGSVERIPEFIARA--KDKNDPFRLMGFGHRVYKN 263

Query: 367 TDPRYTAQREF---ALKHL--PHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQHSGI 421
            DPR    ++     LK L    D +  +  +L ++   + +E    K  +PNVD +SGI
Sbjct: 264 YDPRAKIMQKTCHEVLKELNIQGDPLLDIAMELEKIA--LNDEYFVEKKLYPNVDFYSGI 321

Query: 422 LLRYYGL 428
            L+  G 
Sbjct: 322 TLKALGF 328


ref|ZP_00380229.1| COG0372: Citrate synthase [Brevibacterium linens BL2]
(373 aa)

Score: 74 bits (182), Expect: 5.39506e-12
Length: 337, Idn/Pos/Gap = 87/150/41 (25%/44%/12%)

Query: 127 EGLLWLLLTGEIPTESQVESVCQDLKRRAAVPPEVLRLLDELPHERMHPMTQFSVAVSLL 186
           E + +L+   E+PT++Q+E      + +  +  ++++L+ +LP +  HPM     AVS L
Sbjct:  46 EEVAYLIWNSELPTKAQLEEFQARERGQRGIDDKLVQLILDLPKD-CHPMHVVQTAVSYL 104

Query: 187 QHESKMAEAYAQGAPKSTFWEYCLEDALTLIARLPAVAARIYRNTFHGGKHVPAEKIEKV 246
                 A+   +        E  L  A  L A+LP + A  +R   HG   V   K    
Sbjct: 105 GAVDPDADVEGE--------EANLAKAERLYAQLPTIVAIDHRRR-HGLDPVAPTK---- 151

Query: 247 DDMGMRLARSLGFELNEFDEL--------MRLYLVLHADHEGGNVSAHAVRLVGSALSDP 298
            D+G     +  F    FDE+          + ++L+A+H   N S    R++ S  +D 
Sbjct: 152 -DLGY----AANFFKMVFDEVPDEAVVRCFDISMILYAEHSF-NASTFTTRVITSTTADL 205

Query: 299 YLSFAAGLNGLAGPLHGLANQEVLRWLLQMKEKLGNRPMTTENLRELCWETLREGHVIPG 358
           Y + A G+  L GPLHG AN+ V    + M E++G    T +       + L +   I G
Sbjct: 206 YSAVAGGVGALKGPLHGGANEAV----MAMLEEVG----TADKASAWIDDALAKKAKIMG 257

Query: 359 FGHAVLRRTDPRYTAQREFALKHLPHDEMFQLVSKLYEVVPRVLEEQGKVKNPWPNVDQH 418
           FGH V +  D R    R+ A +++   +    +  LY       E+    K  +PN+D  
Sbjct: 258 FGHRVYKNGDSRVPTMRK-AFENMVEAKGATDLLDLYNAFE---EDFVGRKGIYPNLDYP 313

Query: 419 SGILLRYYGLVESNFYTVLFGVSRALGTLSSLVWDRA 455
           SG      G  +++ +T +F ++R  G  + ++  +A
Sbjct: 314 SGPAYHLMGF-DTDQFTPIFVMARITGWTAHIMEQQA 349