BLAST output

CMQ436C (389 aa)
by blastp 2.2.10 [Oct-19-2004] against nr [Apr-30-2005] (XML result)


		glycolate oxidase-like protein [Arabidopsis thaliana]
		OSJNBa0053K19.8 [Oryza sativa (japonica cultivar-group)]
		glycolate oxidase
		glycolate oxidase [Arabidopsis thaliana]
		glycolate oxidase [Mesembryanthemum crystallinum]
		glycolate oxidase [Arabidopsis thaliana]
		Three-Dimensional Structure Of Glycolate Oxidase With Bound Active-Site Inhibitors
		glycolate oxidase [Zantedeschia aethiopica]
		AT3g14420/MOA2_2 [Arabidopsis thaliana]
		(S)-2-hydroxy-acid oxidase, peroxisomal (Glycolate oxidase) (GOX) (Short chain alpha-hydroxy acid oxidase)
		Chain B, Glycolate Oxidase (E.C.1.1.3.15) Mutant With Tyr 24 Replaced By Phe (Y24f)
		putative glycolate oxidase [Oryza sativa (japonica cultivar-group)]
		(S)-2-hydroxy-acid oxidase (EC 1.1.3.15) - cucurbit
		glycolate oxidase [Oryza sativa]
		unnamed protein product [Tetraodon nigroviridis]
		(S)-2-hydroxy-acid oxidase, peroxisomal, putative / glycolate oxidase, putative / short chain alpha-hydroxy acid oxidase, putative [Arabidopsis thaliana]
		hypothetical protein DDB0184082 [Dictyostelium discoideum]
		hypothetical protein [Homo sapiens]
		a liver-specific gene similar to the plant glycolate oxidase [Homo sapiens]
		PREDICTED: similar to glycolate oxidase; short-chain alpha-hydroxy acid oxidase [Rattus norvegicus]
		hydroxyacid oxidase 1, liver [Mus musculus]
		glycolate oxidase [Arabidopsis thaliana]
		glycolate oxidase, putative [Arabidopsis thaliana]
		(S)-2-hydroxy-acid oxidase, peroxisomal, putative / glycolate oxidase, putative / short chain alpha-hydroxy acid oxidase, putative [Arabidopsis thaliana]
		MGC82107 protein [Xenopus laevis]
		glycolate oxidase [Arabidopsis thaliana]
		LOC402827 protein [Danio rerio]
		glycolate oxidase, putative [Arabidopsis thaliana]
		LOC398510 protein [Xenopus laevis]
		CG30019-PB, isoform B [Drosophila melanogaster]
		Unknown (protein for MGC:108441) [Xenopus tropicalis]
		COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Trichodesmium erythraeum IMS101]
		GA15579-PA [Drosophila pseudoobscura]
		CG30019-PC, isoform C [Drosophila melanogaster]
		putative (S)-2-hydroxy-acid oxidase [Oryza sativa (japonica cultivar-group)]
		ENSANGP00000018221 [Anopheles gambiae str. PEST]
		PREDICTED: similar to glycolate oxidase; short-chain alpha-hydroxy acid oxidase [Canis familiaris]
		hypothetical protein LOC393455 [Danio rerio]
		COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Nostoc punctiforme PCC 73102]
		COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Anabaena variabilis ATCC 29413]
		hypothetical protein F41E6.5 - Caenorhabditis elegans
		glycolate oxidase [Nostoc sp. PCC 7120]
		unnamed protein product [Tetraodon nigroviridis]
		glycolate oxidase [Lycopersicon esculentum]
		Hypothetical protein CBG01477 [Caenorhabditis briggsae]
		PREDICTED: similar to hydroxyacid oxidase 1; (S)-2-hydroxy-acid oxidase; glycolate oxidase [Gallus gallus]
		PREDICTED: similar to Hydroxyacid oxidase 2 (HAOX2) ((S)-2-hydroxy-acid oxidase, peroxisomal) (Long chain alpha-hydroxy acid oxidase) (Long-chain L-2-hydroxy acid oxidase) [Gallus gallus]
		(S)-2-hydroxy-acid oxidase [Deinococcus radiodurans]
		hydroxyacid oxidase 2 (long chain) [Homo sapiens]
		hydroxyacid oxidase 2 (long chain) [Homo sapiens]
		COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Rubrobacter xylanophilus DSM 9941]
		hypothetical protein CNBD4280 [Cryptococcus neoformans var. neoformans B-3501A]
		unnamed protein product [Yarrowia lipolytica CLIB99]
		PREDICTED: similar to Hydroxyacid oxidase 2 (HAOX2) ((S)-2-hydroxy-acid oxidase, peroxisomal) (Long chain alpha-hydroxy acid oxidase) (Long-chain L-2-hydroxy acid oxidase) [Canis familiaris]
		Chain H, Crystal Structure Analysis Of Recombinant Rat Kidney Long- Chain Hydroxy Acid Oxidase
		hydroxyacid oxidase 3 (medium-chain) [Rattus norvegicus]
		OSJNBa0053K19.9 [Oryza sativa (japonica cultivar-group)]
		long-chain L-2-hydroxy acid oxidase [Homo sapiens]
		unnamed protein product [Debaryomyces hansenii CBS767]
		unnamed protein product [Yarrowia lipolytica CLIB99]
		glycolate oxidase [Arabidopsis thaliana]
		L-lactate:cytochrome c oxidoreductase preprotein [Pichia anomala]
		hypothetical protein FG00145.1 [Gibberella zeae PH-1]
		hypothetical protein AN3901.2 [Aspergillus nidulans FGSC A4]
		glycolate oxidase [Medicago sativa]
		putative hydroxymandelate oxidase [Nonomuraea sp. ATCC 39727]
		long chain 2-hydroxy acid oxidase [Mus musculus]
		hypothetical protein FG05328.1 [Gibberella zeae PH-1]
		Hydroxyacid oxidase 3 (HAOX3) ((S)-2-hydroxy-acid oxidase, peroxisomal) (Medium chain alpha-hydroxy acid oxidase) (Medium-chain L-2-hydroxy acid oxidase)
		hydroxyacid oxidase (glycolate oxidase) 3 [Mus musculus]
		COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Azotobacter vinelandii]
		unnamed protein product [Mus musculus]
		hypothetical protein MG01723.4 [Magnaporthe grisea 70-15]
		lactate oxidase [Lactobacillus plantarum WCFS1]
		NAD-independent L-lactate dehydrogenase [Lactobacillus plantarum]
		glycolate oxidase, (S)-2-hydroxy-acid oxidase (EC 1.1.3.15), peroxisomal [Mesorhizobium loti MAFF303099]
		PREDICTED: similar to hydroxyacid oxidase 1, partial [Bos taurus]
		hypothetical protein [Neurospora crassa]
		glycolate oxidase [Hyacinthus orientalis]
		COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Pediococcus pentosaceus ATCC 25745]
		hypothetical protein plu4371 [Photorhabdus luminescens subsp. laumondii TTO1]
		L-lactate oxidase [Lactococcus lactis subsp. lactis Il1403]
		COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Trichodesmium erythraeum IMS101]
		putative glycolate oxidase [Salmonella enterica subsp. enterica serovar Typhi Ty2]
		glycolate oxidase [Laminaria digitata]
		putative oxidase [Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67]
		putative glycolate oxidase [Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150]
		putative oxidase [Salmonella typhimurium LT2]
		COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Polaromonas sp. JS666]
		L-lactate dehydrogenase [Mesorhizobium loti MAFF303099]
		hypothetical protein CNBI2270 [Cryptococcus neoformans var. neoformans B-3501A]
		Chain A, High Resolution Structure Of Reduced Active Mutant Of (S)- Mandelate Dehydrogenase
		unknown protein [synthetic construct]
		L-lactate dehydrogenase [Agrobacterium tumefaciens str. C58]
		glycolate oxidase [Streptomyces lavendulae]
		hypothetical protein AN9014.2 [Aspergillus nidulans FGSC A4]
		L-lactate dehydrogenase [Bordetella parapertussis 12822]
		LldD, L-lactate dehydrogenase [Brucella abortus biovar 1 str. 9-941]
		glycolate oxidase [Mesorhizobium loti MAFF303099]
		hypothetical protein CaO19.12467 [Candida albicans SC5314]
		hypothetical protein FG01812.1 [Gibberella zeae PH-1]
		ENSANGP00000024226 [Anopheles gambiae str. PEST]
		L-LACTATE DEHYDROGENASE (CYTOCHROME) [Brucella melitensis 16M]
		L-lactate dehydrogenase [Bordetella pertussis Tohama I]
		unnamed protein product [Kluyveromyces lactis NRRL Y-1140]
		cytochrome b2 [Kluyveromyces lactis]
		Hypothetical protein F41E6.5 [Caenorhabditis elegans]
		L-lactate dehydrogenase [Rhodopseudomonas palustris CGA009]
		RH48327p [Drosophila melanogaster]
		COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Crocosphaera watsonii WH 8501]
		lactate 2-monooxygenase [Picrophilus torridus DSM 9790]
		L-lactate dehydrogenase [Pseudomonas aeruginosa PAO1]
		PCZA361.2 [Amycolatopsis orientalis]
		Lactate oxidase [Streptococcus pneumoniae R6]
		L-lactate dehydrogenase [Francisella tularensis subsp. tularensis Schu 4]
		COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Lactobacillus casei ATCC 334]
		COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Burkholderia fungorum LB400]
		COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Burkholderia fungorum LB400]
		putative phenylglycolate oxidase [Amycolatopsis balhimycina]
		lactate oxidase [Streptococcus pneumoniae TIGR4]
		PUTATIVE L-LACTATE DEHYDROGENASE (CYTOCHROME) PROTEIN [Sinorhizobium meliloti]
		hypothetical protein AGR_C_4216 [Agrobacterium tumefaciens str. C58]
		putative L-lactate dehydrogenase [Neisseria gonorrhoeae FA 1090]
		COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Psychrobacter sp. 273-4]
		glycolate oxidase [Lactobacillus johnsonii NCC 533]
		Chain B, Flavocytochrome B2, Arg289lys Mutant
		glycolate oxidase [Nicotiana tabacum]
		lactate oxidase [Streptococcus iniae]
		COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Enterococcus faecium]
		L-lactate dehydrogenase [Bradyrhizobium japonicum USDA 110]
		unnamed protein product [Debaryomyces hansenii CBS767]
		COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Lactobacillus gasseri]
		L-lactate dehydrogenase [Neisseria meningitidis MC58]
		L-lactate dehydrogenase [Neisseria meningitidis Z2491]
		Chain B, Flavocytochrome B2 (E.C.1.1.2.3) Complexed With Sulfite
		cytochrome b2 precursor [Saccharomyces cerevisiae]
		Chain B, Crystallographic Study Of The Recombinant Flavin-Binding Domain Of Baker's Yeast Flavocytochrome B2: Comparison With The Intact Wild-Type Enzyme
		Chain B, L230a Mutant Flavocytochrome B2 With Benzoylformate
		COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Mesorhizobium sp. BNC1]
		Chain B, Crystallographic Study Of The Recombinant Flavin-Binding Domain Of Baker's Yeast Flavocytochrome B2: Comparison With The Intact Wild-Type Enzyme
		hypothetical protein ELI1927 [Erythrobacter litoralis HTCC2594]
		hypothetical protein FG04988.1 [Gibberella zeae PH-1]
		L-lactate dehydrogenase, putative [Silicibacter pomeroyi DSS-3]
		Chain B, L-Lactate Dehydrogenase: Cytochrome C Oxidoreductase (Flavocytochrome B2) (E.C.1.1.2.3) Mutant With Tyr 143 Replaced By Phe (Y143f) Complexed With Pyruvate
		Chain B, A198g:l230a Flavocytochrome B2 With Sulfite Bound
		hypothetical protein CNBL1170 [Cryptococcus neoformans var. neoformans B-3501A]
		cytochrome b2, mitochondrial precursor, putative [Cryptococcus neoformans var. neoformans JEC21]
		putative L-lactate dehydrogenase (cytochrome) protein [Sinorhizobium meliloti 1021]
		unnamed protein product [Candida glabrata CBS138]
		L-lactate oxidase [Streptococcus pyogenes MGAS10394]
		putative lactate oxidase [Streptococcus pyogenes MGAS8232]
		hypothetical protein AN2590.2 [Aspergillus nidulans FGSC A4]
		hypothetical protein FG03709.1 [Gibberella zeae PH-1]
		Hmo [Streptomyces toyocaensis]
		COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Ferroplasma acidarmanus]
		putative lactate oxidase [Streptococcus pyogenes M1 GAS]
		COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Polaromonas sp. JS666]
		S-mandelate dehydrogenase [Pseudomonas putida]
		COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Enterococcus faecium]
		glycolate oxidase, (S)-2-hydroxy-acid oxidase, peroxisomal [Nitrosomonas europaea ATCC 19718]
		NocN [Nocardia uniformis subsp. tsuyamanensis]
		putative L-lactate dehydrogenase [Burkholderia pseudomallei K96243]
		LldD [Pasteurella multocida subsp. multocida str. Pm70]
		putative lactate oxidase [Streptococcus pyogenes MGAS315]
		putative lactate oxidase [Streptococcus pyogenes SSI-1]
		hypothetical protein plu1106 [Photorhabdus luminescens subsp. laumondii TTO1]
		COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Silicibacter sp. TM1040]
		COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Brevibacterium linens BL2]
		Lactate 2-monooxygenase (Lactate oxidase)
		L-mandelate dehydrogenase [Rhodotorula graminis]
		L-mandelate dehydrogenase [Rhodotorula graminis]
		COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Rhodobacter sphaeroides 2.4.1]
		COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Rubrobacter xylanophilus DSM 9941]
		hypothetical protein [Neurospora crassa]
		COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Rubrivivax gelatinosus PM1]
		L-lactate dehydrogenase [Vibrio parahaemolyticus RIMD 2210633]
		COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Rubrivivax gelatinosus PM1]
		hypothetical protein MG07635.4 [Magnaporthe grisea 70-15]
		dehydrogenase [Streptomyces rishiriensis]
		COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Ralstonia metallidurans CH34]
		L-lactate dehydrogenase [Erwinia carotovora subsp. atroseptica SCRI1043]
		L-lactate dehydrogenase (FMN-dependent) related enzyme [Prochlorococcus marinus subsp. marinus str. CCMP1375]
		hypothetical protein UM00123.1 [Ustilago maydis 521]
		hypothetical protein CNBB4110 [Cryptococcus neoformans var. neoformans B-3501A]
		MdlB [Pseudomonas fluorescens]
		hypothetical protein AN4424.2 [Aspergillus nidulans FGSC A4]
		L-lactate dehydrogenase [Yersinia pseudotuberculosis IP 32953]
		hypothetical protein AN7984.2 [Aspergillus nidulans FGSC A4]
		COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Ralstonia eutropha JMP134]
		L-lactate 2-monooxygenase [Caulobacter crescentus CB15]
		hypothetical protein UM04746.1 [Ustilago maydis 521]
		hypothetical protein [Neurospora crassa]
		hypothetical protein CNBI3650 [Cryptococcus neoformans var. neoformans B-3501A]
		HmO protein [Actinoplanes teichomyceticus]
		Lactate oxidase - Aerococcus viridans
		putative L-lactate dehydrogenase [Alcaligenes faecalis]
		L-lactate dehydrogenase [Bradyrhizobium japonicum USDA 110]
		L-lactate oxidase, LOX [Aerococcus viridans, IFO12219, Peptide, 371 aa]
		L-lactate dehydrogenase [Pseudomonas putida KT2440]
		L-lactate dehydrogenase [Vibrio cholerae O1 biovar eltor str. N16961]
		COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Actinobacillus pleuropneumoniae serovar 1 str. 4074]
		hypothetical protein FG03984.1 [Gibberella zeae PH-1]
		L-lactate dehydrogenase [Xanthomonas axonopodis pv. citri str. 306]
		L-lactate dehydrogenase [Xanthomonas campestris pv. campestris str. ATCC 33913]
		FMN-dependent dehydrogenase [Bordetella bronchiseptica RB50]
		L-lactate dehydrogenase [Xanthomonas oryzae pv. oryzae KACC10331]
		hypothetical protein AN8744.2 [Aspergillus nidulans FGSC A4]
		hypothetical protein MAP3486 [Mycobacterium avium subsp. paratuberculosis str. k10]
		L-lactate dehydrogenase [Bradyrhizobium japonicum USDA 110]
		putative dehydrogenase [Burkholderia pseudomallei K96243]
		L-lactate dehydrogenase, FMN linked [Acinetobacter sp. ADP1]
		hypothetical protein CNBD2850 [Cryptococcus neoformans var. neoformans B-3501A]
		L-lactate dehydrogenase LctD [Haemophilus influenzae Rd KW20]
		Putative oxidoreductase [Gluconobacter oxydans 621H]
		putative L-lactate dehydrogenase [Nocardia farcinica IFM 10152]
		L-lactate dehydrogenase [Bartonella henselae str. Houston-1]
		lctD [Escherichia coli]
		COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Haemophilus influenzae R2866]
		L-lactate dehydrogenase [Shigella flexneri 2a str. 301]
		FMN-dependent dehydrogenase [Pseudomonas resinovorans]
		L-lactate dehydrogenase [Escherichia coli K12]
		COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Haemophilus influenzae R2846]
		L-lactate dehydrogenase [Escherichia coli CFT073]
		PA4771 [synthetic construct]
		L-lactate dehydrogenase [Haemophilus ducreyi 35000HP]
		putative glycolate oxidase [Streptomyces coelicolor A3(2)]
		L-lactate dehydrogenase [Pseudomonas aeruginosa PAO1]
		COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Brevibacterium linens BL2]
		COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Pseudomonas aeruginosa UCBPP-PA14]
		L-lactate dehydrogenase [Bartonella quintana str. Toulouse]
		hypothetical protein MG05735.4 [Magnaporthe grisea 70-15]
		hypothetical protein MAP2959c [Mycobacterium avium subsp. paratuberculosis str. k10]
		L-lactate dehydrogenase [Salmonella typhimurium LT2]
		putative FMN-dependent [Sinorhizobium meliloti 1021]
		L-lactate dehydrogenase [Mycobacterium leprae TN]
		putative L-lactate dehydrogenase [Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150]
		putative L-lactate dehydrogenase [Salmonella enterica subsp. enterica serovar Typhi Ty2]
		LldD2 [Mycobacterium avium subsp. paratuberculosis str. k10]
		COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Pseudomonas syringae pv. syringae B728a]
		COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Burkholderia fungorum LB400]
		POSSIBLE L-LACTATE DEHYDROGENASE (CYTOCHROME) LLDD2 [Mycobacterium tuberculosis H37Rv]
		L-lactate dehydrogenase [Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67]
		POSSIBLE L-LACTATE DEHYDROGENASE (CYTOCHROME) LLDD2 [Mycobacterium bovis AF2122/97]
		hypothetical protein AN5146.2 [Aspergillus nidulans FGSC A4]
		hypothetical protein FG03439.1 [Gibberella zeae PH-1]
		L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Corynebacterium glutamicum ATCC 13032]
		COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Ralstonia eutropha JMP134]
		PUTATIVE L-LACTATE DEHYDROGENASE [Corynebacterium glutamicum ATCC 13032]
		putative L-lactate 2-monooxygenase [Streptomyces avermitilis MA-4680]
		glycolate oxidase [Arabidopsis thaliana]
		hypothetical protein AN4421.2 [Aspergillus nidulans FGSC A4]
		hypothetical protein MG00335.4 [Magnaporthe grisea 70-15]
		lactate dehydrogenase [Bordetella pertussis Tohama I]
		unknown [Rhodococcus erythropolis]
		COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Novosphingobium aromaticivorans DSM 12444]
		putative L-lactate dehydrogenase [Bordetella parapertussis 12822]
		putative L-lactate dehydrogenase [Corynebacterium efficiens YS-314]
		COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Rubrobacter xylanophilus DSM 9941]
		hypothetical protein FG01027.1 [Gibberella zeae PH-1]
		unnamed protein product [Kluyveromyces lactis NRRL Y-1140]
		hypothetical protein AN8587.2 [Aspergillus nidulans FGSC A4]
		putative L-lactate dehydrogenase [Bordetella bronchiseptica RB50]
		LldD1 [Mycobacterium avium subsp. paratuberculosis str. k10]
		putative dehydrogenase [Nocardia farcinica IFM 10152]
		hypothetical protein UM04504.1 [Ustilago maydis 521]
		COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Novosphingobium aromaticivorans DSM 12444]
		putative FMN-dependent dehydrogenase [Escherichia coli]
		FMN-dependent alpha-hydroxy acid dehydrogenase family protein [Mycobacterium tuberculosis CDC1551]
		putative dehydrogenase [Nocardia farcinica IFM 10152]
		putative dehydrogenase [Nocardia farcinica IFM 10152]
		lactate 2-monooxygenase [Thermus thermophilus HB27]
		SPAPB1A11.03 [Schizosaccharomyces pombe]
		POSSIBLE L-LACTATE DEHYDROGENASE (CYTOCHROME) LLDD1 [Mycobacterium tuberculosis H37Rv]
		PUTATIVE L-LACTATE DEHYDROGENASE (CYTOCHROME) PROTEIN [Sinorhizobium meliloti]
		PREDICTED: similar to hydroxyacid oxidase 1, partial [Bos taurus]
		COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Burkholderia fungorum LB400]
		COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Thermobifida fusca]
		putative oxidoreductase [Streptomyces coelicolor A3(2)]
		LOC398510 protein [Xenopus laevis]
		putative L-lactate dehydrogenase [Bordetella pertussis Tohama I]
		FMN-dependent alpha-hydroxy acid dehydrogenase family protein [Silicibacter pomeroyi DSS-3]
		COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Magnetospirillum magnetotacticum MS-1]
		putative L(+)-mandelate dehydrogenase [Burkholderia pseudomallei K96243]
		putative glycolate oxidase [Vitis vinifera]
		L-lactate dehydrogenase [Caulobacter crescentus CB15]
		COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Silicibacter sp. TM1040]
		COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Mesorhizobium sp. BNC1]
		COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Lactobacillus casei ATCC 334]
		hypothetical protein FG01531.1 [Gibberella zeae PH-1]
		hypothetical protein [Neurospora crassa]
		FMN-dependent alpha-hydroxy acid dehydrogenase family protein [Silicibacter pomeroyi DSS-3]
		hypothetical protein AN7055.2 [Aspergillus nidulans FGSC A4]
		hypothetical protein MG09162.4 [Magnaporthe grisea 70-15]
		COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365]
		PREDICTED: similar to hydroxyacid oxidase 2 (long chain), partial [Bos taurus]
		COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Burkholderia fungorum LB400]
		PREDICTED: similar to Hydroxyacid oxidase 2 (HAOX2) ((S)-2-hydroxy-acid oxidase, peroxisomal) (Long chain alpha-hydroxy acid oxidase) (Long-chain L-2-hydroxy acid oxidase) [Pan troglodytes]
		NT02FT1139 [synthetic construct]
		probable glycolate oxidase [Clostridium perfringens str. 13]
		hydroxyacid oxidase 2 (long chain) [Homo sapiens]
		hypothetical protein, similar to C-terminal part of L-lactate dehydrogenase (cytochrome) LldD [Sinorhizobium meliloti 1021]
		PREDICTED: similar to glycolate oxidase; short-chain alpha-hydroxy acid oxidase, partial [Bos taurus]
		COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Desulfovibrio desulfuricans G20]
		L-lactate dehydrogenase [Leptospira interrogans serovar Lai str. 56601]
		putative glycolate oxidase [Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130]
		hypothetical protein [Desulfotalea psychrophila LSv54]
		hypothetical protein FG05883.1 [Gibberella zeae PH-1]
		dehydrogenase, FMN-dependent family [Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough]
		NT02FT1138 [synthetic construct]
		L-lactate dehydrogenase, cytochrome-type (lldD) [Archaeoglobus fulgidus DSM 4304]
		dehydrogenase [Agrobacterium tumefaciens str. C58]
		COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Haemophilus influenzae 86-028NP]
		PREDICTED: similar to glycolate oxidase; short-chain alpha-hydroxy acid oxidase, partial [Bos taurus]
		glycolate oxidase like protein [Arabidopsis thaliana]
		lactate 2-monooxygenase [Lactobacillus delbrueckii subsp. lactis]
		putative (s)-2-hydroxy-acid oxidase [Pinus pinaster]
		hypothetical protein AGR_pAT_479 [Agrobacterium tumefaciens str. C58]
		PREDICTED: similar to Hydroxyacid oxidase 2 (HAOX2) ((S)-2-hydroxy-acid oxidase, peroxisomal) (Long chain alpha-hydroxy acid oxidase) (Long-chain L-2-hydroxy acid oxidase), partial [Bos taurus]
		glycolate oxidase [Lactobacillus acidophilus NCFM]
		glycolate oxidase [Lactuca sativa]
		COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Methanosarcina barkeri str. fusaro]
		hypothetical protein TDE0859 [Treponema denticola ATCC 35405]
		T. pallidum predicted coding region TP0291 [Treponema pallidum subsp. pallidum str. Nichols]
		FMN-dependent membrane-bound L(+)-mandelate dehydrogenase {N-terminal} [Pseudomonas putida, Peptide Partial, 58 aa]
		Isopentenyl-diphosphate delta-isomerase [Methanosarcina mazei Go1]
		Isopentenyl-diphosphate delta-isomerase (IPP isomerase) (Isopentenyl pyrophosphate isomerase)
		L-lactate dehydrogenase (FMN-dependent) [Methanopyrus kandleri AV19]
		COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Methanococcoides burtonii DSM 6242]
		isopentenyl-diphosphate delta-isomerase [Methanosarcina acetivorans C2A]
		isopentenyl-pyrophosphate isomerase [Leishmania major]
		hypothetical protein [Legionella pneumophila str. Lens]
		inosine-5'-monophosphate dehydrogenase [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
		isopentenyl-diphosphate delta-isomerase, putative [Entamoeba histolytica HM-1:IMSS]
		conserved hypothetical protein [uncultured archaeon GZfos18C8]
		L-lactate dehydrogenase [uncultured archaeon GZfos26E7]
		isopentenyl-pyrophosphate isomerase [Trypanosoma brucei brucei]
		inosine-5'-monophosphate dehydrogenase [Mycoplasma penetrans HF-2]
		conserved protein [Methanothermobacter thermautotrophicus str. Delta H]
		IMP dehydrogenase family protein [Dehalococcoides ethenogenes 195]
		COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Crocosphaera watsonii WH 8501]
		fnI isopentenyl-diphosphate delta-isomerase (IPP isomerase) (EC 5.3.3.2) [Pyrococcus abyssi GE5]
		Isopentenyl-diphosphate delta-isomerase (IPP isomerase) (Isopentenyl pyrophosphate isomerase)
		IMP dehydrogenase [Clostridium acetobutylicum ATCC 824]
		COG0516: IMP dehydrogenase/GMP reductase [Trichodesmium erythraeum IMS101]
		carotenoid biosynthetic gene ERWCRTS, putative [Archaeoglobus fulgidus DSM 4304]
		inosine-5-monophosphate dehydrogenase [EC:1.1.1.205] [Cryptosporidium parvum]
		inosine-5'-monophosphate dehydrogenase, probable [Cryptosporidium parvum]
		COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Rubrobacter xylanophilus DSM 9941]
		hypothetical protein PF0856 [Pyrococcus furiosus DSM 3638]
		COG0516: IMP dehydrogenase/GMP reductase [Xylella fastidiosa Dixon]
		IMP dehydrogenase / GMP reductase [Propionibacterium acnes KPA171202]
		inosine-5'-monophosphate dehydrogenase [Xylella fastidiosa Temecula1]
		COG0516: IMP dehydrogenase/GMP reductase [Xylella fastidiosa Ann-1]
		IMP dehydrogenase/GMP reductase [Prochlorococcus marinus subsp. marinus str. CCMP1375]
		inosine-5'-monophosphate dehydrogenase [Xylella fastidiosa 9a5c]
		Chain B, Crystal Structure Of Inosine-5'-Monophosphate Dehydrogenase (Tm1347) From Thermotoga Maritima At 2.18 A Resolution
		inosine-5'-monophosphate dehydrogenase [Thermotoga maritima MSB8]
		Inosinic acid dehydrogenase GuaB [Helicobacter hepaticus ATCC 51449]
		hypothetical protein PH1202 [Pyrococcus horikoshii OT3]
		COG0516: IMP dehydrogenase/GMP reductase [Dechloromonas aromatica RCB]
		inosine-5'-monophosphate dehydrogenase [Xanthomonas oryzae pv. oryzae KACC10331]
		inosine-5'-monophosphate dehydrogenase [Xanthomonas axonopodis pv. citri str. 306]
		isopentenyl-diphosphate delta-isomerase [Streptococcus agalactiae 2603V/R]
		inosine-5'-monophosphate dehydrogenase [Xanthomonas campestris pv. campestris str. ATCC 33913]
		Unknown [Streptococcus agalactiae NEM316]
		COG0516: IMP dehydrogenase/GMP reductase [Ralstonia eutropha JMP134]
		inosine-5-monophosphate dehydrogenase [Clostridium tetani E88]
		IMP dehydrogenase [Gloeobacter violaceus PCC 7421]
		COG0516: IMP dehydrogenase/GMP reductase [Thermobifida fusca]
		isopentenyl diphosphate isomerase [Sulfolobus shibatae]
		Glutamate synthase subunit 2 [Methanopyrus kandleri AV19]
		isopentenyl diphosphate isomerase [Bacillus subtilis]
		glutamate synthase (NADPH), alpha subunit [Methanothermobacter thermautotrophicus str. Delta H]
		putative IMP dehydrogenase [Prochlorococcus marinus subsp. pastoris str. CCMP1986]
		COG0516: IMP dehydrogenase/GMP reductase [Crocosphaera watsonii WH 8501]
		COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Lactobacillus casei ATCC 334]
		IMP dehydrogenase subunit [Synechocystis sp. PCC 6803]
		COG0516: IMP dehydrogenase/GMP reductase [Burkholderia fungorum LB400]
		Inosine-5'-monophosphate dehydrogenase (IMP dehydrogenase) (IMPDH) (IMPD)
		Isopentenyl-diphosphate delta-isomerase [Bdellovibrio bacteriovorus HD100]
		glutamate synthase subunit alpha [Pyrococcus furiosus DSM 3638]
		COG0516: IMP dehydrogenase/GMP reductase [Haemophilus somnus 2336]
		orf c05008 [Sulfolobus solfataricus]

emb|CAB78838.1| glycolate oxidase-like protein [Arabidopsis thaliana]
emb|CAA16716.1| glycolate oxidase - like protein [Arabidopsis thaliana]
gb|AAN71944.1| putative glycolate oxidase [Arabidopsis thaliana]
ref|NP_193570.1| (S)-2-hydroxy-acid oxidase, peroxisomal, putative / glycolate oxidase, putative / short chain alpha-hydroxy acid oxidase, putative [Arabidopsis thaliana]
pir||G85206 glycolate oxidase-like protein [imported] - Arabidopsis thaliana
pir||T04532 probable (S)-2-hydroxy-acid oxidase (EC 1.1.3.15), peroxisomal - Arabidopsis thaliana (fragment)
(368 aa)

Score: 434 bits (1115), Expect: 3.07002e-120
Length: 371, Idn/Pos/Gap = 219/283/7 (59%/76%/1%)

Query:  15 NLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQV  74
           N+ EY   AK +LP MVY YYASGA+D+ TL++N  AF R+ FRPR+LIDVS++D++  V
Sbjct:   5 NVMEYEKIAKEKLPKMVYDYYASGAEDQWTLQENRNAFSRILFRPRILIDVSKIDVSTTV  64

Query:  75 MGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLP 134
           +G ++S P+M+APTAMQ+MAHP+GELATARA +  GT+M LSSWAT S+E+VA+  PG+ 
Sbjct:  65 LGFNISMPIMIAPTAMQKMAHPDGELATARATSAAGTIMTLSSWATCSVEEVASTGPGI- 123

Query: 135 KFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANF 194
           +FFQLYVYKDR +  +LV+RAE AGF+AIALTVDTP+LGRRE+DI+N+F LP  L+L NF
Sbjct: 124 RFFQLYVYKDRNVVIQLVKRAEEAGFKAIALTVDTPRLGRRESDIKNRFALPRGLTLKNF 183

Query: 195 ADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQRA 254
             + D  ++      SGLASYVA  +D SL+W DI WL+SIT LPIL+KGV+TAEDA+ A
Sbjct: 184 EGL-DLGKIDK-TNDSGLASYVAGQVDQSLSWKDIKWLQSITSLPILVKGVITAEDARIA 241

Query: 255 LQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALALG 314
           ++YGA GI +SNHGARQLD V ATI  LEEV ++V GRIPVF+D GVRRGTDV KALALG
Sbjct: 242 VEYGAAGIIVSNHGARQLDYVPATIVALEEVVKAVEGRIPVFLDGGVRRGTDVFKALALG 301

Query: 315 ADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLVVRDAFAP 374
           A  V +GRP ++ LA DGE GV ++L +L+DEF+L M L GC+ + +I R  +  D    
Sbjct: 302 ASGVFVGRPSLFSLAADGEAGVRKMLQMLRDEFELTMALSGCRSLREISRTHIKTD---- 357

Query: 375 YDVRQMLSVKM 385
           +D    LS K+
Sbjct: 358 WDTPHYLSAKL 368

ref|XP_473942.1| OSJNBa0053K19.8 [Oryza sativa (japonica cultivar-group)]
emb|CAE03500.2| OSJNBa0053K19.8 [Oryza sativa (japonica cultivar-group)]
(367 aa)

Score: 431 bits (1109), Expect: 1.47362e-119
Length: 357, Idn/Pos/Gap = 216/282/3 (60%/78%/0%)

Query:  15 NLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQV  74
           N++EY   AK +LP M+Y YYASGA+D+ TL++N EAF R+ FRPR+LIDVSR+++   V
Sbjct:   6 NVSEYEQLAKQKLPKMIYDYYASGAEDQWTLKENREAFSRILFRPRILIDVSRINMATNV  65

Query:  75 MGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLP 134
           +G ++S P+M+AP+AMQ+MAHPEGELATARA +  GT+M LSSW+T+S+E+V +  PG+ 
Sbjct:  66 LGFNISMPIMIAPSAMQKMAHPEGELATARAASAAGTIMTLSSWSTSSVEEVNSAAPGI- 124

Query: 135 KFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANF 194
           +FFQLYVYKDR I  +LVRRAE AGF+AIALTVDTP+LGRREADI+N+F LPPHL L NF
Sbjct: 125 RFFQLYVYKDRNIVRQLVRRAELAGFKAIALTVDTPRLGRREADIKNRFNLPPHLVLKNF 184

Query: 195 ADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQRA 254
             + D  ++      SGLASYVAS +D SL+W D+ WL++IT LPIL+KGV+TAED + A
Sbjct: 185 EAL-DLGKMDK-TNDSGLASYVASQVDRSLSWTDVKWLQTITSLPILVKGVMTAEDTRLA 242

Query: 255 LQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALALG 314
           ++ GA GI +SNHGARQLD V ATI CLEEV +  +GR+PVF+D GVRRGTDV KALALG
Sbjct: 243 VESGAAGIIVSNHGARQLDYVPATISCLEEVVREAKGRLPVFLDGGVRRGTDVFKALALG 302

Query: 315 ADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLVVRDA 371
           A  V IGRP+++ LAVDGE GV ++L +L+DE +L M L GC  +++I R+ V+ D+
Sbjct: 303 ASGVFIGRPVLFSLAVDGEAGVRKVLQMLRDELELTMALSGCTSLAEITRNHVITDS 359

prf||1803516A glycolate oxidase
(371 aa)

Score: 427 bits (1099), Expect: 2.29385e-118
Length: 360, Idn/Pos/Gap = 220/284/3 (61%/78%/0%)

Query:  15 NLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQV  74
           N++EY   AK +LP MV+ YYASGA+D+ TL++N  AF R+ FRPR+LIDVS++D+T  V
Sbjct:   5 NVSEYENVAKQKLPKMVFDYYASGAEDQWTLQENRNAFSRILFRPRILIDVSKIDMTTTV  64

Query:  75 MGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLP 134
           +G  +S P+M+APTAMQ+MAHPEGE ATARA +  GT+M LSSWAT+S+E+VA+  PG+ 
Sbjct:  65 LGFKISMPIMIAPTAMQKMAHPEGEYATARAASAAGTIMTLSSWATSSVEEVASTGPGI- 123

Query: 135 KFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANF 194
           +FFQLYVYKDR +  +LVRRAERAGF+AIALTVDTP+LGRREADI+N+F LPP LSL NF
Sbjct: 124 RFFQLYVYKDRNVVAQLVRRAERAGFKAIALTVDTPRLGRREADIKNRFVLPPFLSLKNF 183

Query: 195 ADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQRA 254
             + D  ++   A  SGLASYVA  ID SL+W D+ WL++IT LPIL+KGV+TAEDA+ A
Sbjct: 184 EGL-DLGKMDQ-ANDSGLASYVAGQIDRSLSWKDVKWLQTITSLPILVKGVLTAEDARIA 241

Query: 255 LQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALALG 314
           +Q GA GI +SNHGARQLD V ATI  LEEV ++ +GR+PVF+D GVRRGTDV KALALG
Sbjct: 242 VQSGAAGIIVSNHGARQLDYVLATISALEEVVKAAQGRVPVFLDGGVRRGTDVFKALALG 301

Query: 315 ADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLVVRDAFAP 374
           A  V IGRP+V+ LA +GE GV ++L +L+DEF++ M L GC+ + +I R+++V D   P
Sbjct: 302 ARGVFIGRPVVFSLAAEGEVGVKKVLQMLRDEFEMTMTLSGCRSLKEITREMIVADWDTP 361

dbj|BAB01334.1| glycolate oxidase [Arabidopsis thaliana]
gb|AAL69528.1| AT3g14420/MOA2_2 [Arabidopsis thaliana]
gb|AAL16164.1| AT3g14420/MOA2_2 [Arabidopsis thaliana]
gb|AAK96642.1| AT3g14420/MOA2_2 [Arabidopsis thaliana]
sp|Q9LRR9|GOX2_ARATH Probable (S)-2-hydroxy-acid oxidase, peroxisomal 2 (Glycolate oxidase 2) (GOX 2) (Short chain alpha-hydroxy acid oxidase 2)
ref|NP_850584.1| (S)-2-hydroxy-acid oxidase, peroxisomal, putative / glycolate oxidase, putative / short chain alpha-hydroxy acid oxidase, putative [Arabidopsis thaliana]
ref|NP_188060.1| (S)-2-hydroxy-acid oxidase, peroxisomal, putative / glycolate oxidase, putative / short chain alpha-hydroxy acid oxidase, putative [Arabidopsis thaliana]
(367 aa)

Score: 426 bits (1095), Expect: 6.08881e-118
Length: 360, Idn/Pos/Gap = 216/283/3 (60%/78%/0%)

Query:  15 NLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQV  74
           N+ EY   AK +LP MVY YYASGA+D+ TL++N  AF R+ FRPR+LIDVS++D+T  V
Sbjct:   5 NVTEYDAIAKQKLPKMVYDYYASGAEDQWTLQENRNAFARILFRPRILIDVSKIDMTTTV  64

Query:  75 MGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLP 134
           +G  +S P+MVAPTAMQ+MAHP+GE ATARA +  GT+M LSSWAT+S+E+VA+  PG+ 
Sbjct:  65 LGFKISMPIMVAPTAMQKMAHPDGEYATARAASAAGTIMTLSSWATSSVEEVASTGPGI- 123

Query: 135 KFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANF 194
           +FFQLYVYK+R + E+LVRRAERAGF+AIALTVDTP+LGRRE+DI+N+F LPP+L+L NF
Sbjct: 124 RFFQLYVYKNRNVVEQLVRRAERAGFKAIALTVDTPRLGRRESDIKNRFTLPPNLTLKNF 183

Query: 195 ADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQRA 254
             + D  ++   A  SGLASYVA  ID +L+W D+ WL++IT+LPIL+KGV+T EDA+ A
Sbjct: 184 EGL-DLGKMDE-ANDSGLASYVAGQIDRTLSWKDVQWLQTITKLPILVKGVLTGEDARIA 241

Query: 255 LQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALALG 314
           +Q GA GI +SNHGARQLD V ATI  LEEV ++ +GRIPVF+D GVRRGTDV KALALG
Sbjct: 242 IQAGAAGIIVSNHGARQLDYVPATISALEEVVKATQGRIPVFLDGGVRRGTDVFKALALG 301

Query: 315 ADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLVVRDAFAP 374
           A  + IGRP+V+ LA +GE GV ++L +L+DEF+L M L GC+ + +I R+ +  +   P
Sbjct: 302 ASGIFIGRPVVFSLAAEGEAGVRKVLQMLRDEFELTMALSGCRSLKEISRNHITTEWDTP 361

gb|AAB40396.1| glycolate oxidase [Mesembryanthemum crystallinum]
(370 aa)

Score: 425 bits (1092), Expect: 1.30102e-117
Length: 356, Idn/Pos/Gap = 216/280/3 (60%/78%/0%)

Query:  15 NLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQV  74
           N+ EY   AK +LP MVY YYASGA+D+ TL +N  AF R+ FRPR+LIDV+++D+T  V
Sbjct:   5 NVNEYEAIAKQKLPKMVYDYYASGAEDQWTLAENRNAFSRILFRPRILIDVTKIDMTTTV  64

Query:  75 MGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLP 134
           +G  +S P+M+APTAMQ+MAHPEGE ATARA +  GT+M LSSWAT+S+E+VA+  PG+ 
Sbjct:  65 LGFKISMPIMIAPTAMQKMAHPEGEYATARAASAAGTIMTLSSWATSSVEEVASTGPGI- 123

Query: 135 KFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANF 194
           +FFQLYVYK+R + E+LVRRAERAGF+AIALTVDTP+LGRREADI+N+F LPP L+L NF
Sbjct: 124 RFFQLYVYKNRNVVEQLVRRAERAGFKAIALTVDTPRLGRREADIKNRFTLPPFLTLKNF 183

Query: 195 ADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQRA 254
             + D   +   A  SGLASYVA  ID SL+W D+ WL++IT LPIL+KGV+TAEDA+ +
Sbjct: 184 EGL-DLGTMDK-ADDSGLASYVAGQIDRSLSWKDVKWLQTITSLPILVKGVLTAEDARLS 241

Query: 255 LQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALALG 314
           +Q GA GI +SNHGARQLD V +TI  LEEV ++ +GRIPVF+D GVRRGTDV KALALG
Sbjct: 242 VQNGAAGIIVSNHGARQLDYVPSTIMALEEVVKATQGRIPVFLDGGVRRGTDVFKALALG 301

Query: 315 ADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLVVRD 370
           A  + IGRP+V+ LA +GE GV ++L +++DEF+L M L GC+ + +I R+ +V D
Sbjct: 302 ASGIFIGRPVVFSLAAEGEAGVRKVLQMMRDEFELTMALSGCRSIQEISRNHIVAD 357

gb|AAM97068.1| glycolate oxidase [Arabidopsis thaliana]
dbj|BAD95441.1| glycolate oxidase like protein [Arabidopsis thaliana]
gb|AAL24203.1| AT3g14420/MOA2_2 [Arabidopsis thaliana]
gb|AAN72140.1| glycolate oxidase [Arabidopsis thaliana]
ref|NP_188059.1| (S)-2-hydroxy-acid oxidase, peroxisomal, putative / glycolate oxidase, putative / short chain alpha-hydroxy acid oxidase, putative [Arabidopsis thaliana]
sp|Q9LRS0|GOX1_ARATH Probable (S)-2-hydroxy-acid oxidase, peroxisomal 1 (Glycolate oxidase 1) (GOX 1) (Short chain alpha-hydroxy acid oxidase 1)
(367 aa)

Score: 425 bits (1092), Expect: 1.32291e-117
Length: 360, Idn/Pos/Gap = 214/283/3 (59%/78%/0%)

Query:  15 NLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQV  74
           N+ EY   AKA+LP MVY YYASGA+D+ TL++N  AF R+ FRPR+LIDV+++D+   V
Sbjct:   5 NVTEYDAIAKAKLPKMVYDYYASGAEDQWTLQENRNAFARILFRPRILIDVNKIDMATTV  64

Query:  75 MGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLP 134
           +G  +S P+MVAPTA Q+MAHP+GE ATARA +  GT+M LSSWAT+S+E+VA+  PG+ 
Sbjct:  65 LGFKISMPIMVAPTAFQKMAHPDGEYATARAASAAGTIMTLSSWATSSVEEVASTGPGI- 123

Query: 135 KFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANF 194
           +FFQLYVYK+R + E+LVRRAE+AGF+AIALTVDTP+LGRRE+DI+N+F LPP+L+L NF
Sbjct: 124 RFFQLYVYKNRKVVEQLVRRAEKAGFKAIALTVDTPRLGRRESDIKNRFTLPPNLTLKNF 183

Query: 195 ADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQRA 254
             + D  ++   A  SGLASYVA  ID +L+W DI WL++IT +PIL+KGV+T EDA+ A
Sbjct: 184 EGL-DLGKMDE-ANDSGLASYVAGQIDRTLSWKDIQWLQTITNMPILVKGVLTGEDARIA 241

Query: 255 LQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALALG 314
           +Q GA GI +SNHGARQLD V ATI  LEEV ++ +GR+PVF+D GVRRGTDV KALALG
Sbjct: 242 IQAGAAGIIVSNHGARQLDYVPATISALEEVVKATQGRVPVFLDGGVRRGTDVFKALALG 301

Query: 315 ADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLVVRDAFAP 374
           A  + IGRP+V+ LA +GE GV ++L +L+DEF+L M L GC+ +S+I R+ +V +   P
Sbjct: 302 ASGIFIGRPVVFALAAEGEAGVKKVLQMLRDEFELTMALSGCRSLSEITRNHIVTEWDTP 361

pdb|1AL8| Three-Dimensional Structure Of Glycolate Oxidase With Bound Active-Site Inhibitors
pdb|1AL7| Three-Dimensional Structures Of Glycolate Oxidase With Bound Active-Site Inhibitors
(359 aa)

Score: 425 bits (1092), Expect: 1.41423e-117
Length: 356, Idn/Pos/Gap = 217/279/3 (60%/78%/0%)

Query:  15 NLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQV  74
           N+ EY   AK +LP MVY YYASGA+D+ TL +N  AF R+ FRPR+LIDV+ +D+T  +
Sbjct:   5 NVNEYEAIAKQKLPKMVYDYYASGAEDQWTLAENRNAFSRILFRPRILIDVTNIDMTTTI  64

Query:  75 MGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLP 134
           +G  +S P+M+APTAMQ+MAHPEGE ATARA +  GT+M LSSWAT+S+E+VA+  PG+ 
Sbjct:  65 LGFKISMPIMIAPTAMQKMAHPEGEYATARAASAAGTIMTLSSWATSSVEEVASTGPGI- 123

Query: 135 KFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANF 194
           +FFQLYVYKDR +  +LVRRAERAGF+AIALTVDTP+LGRREADI+N+F LPP L+L NF
Sbjct: 124 RFFQLYVYKDRNVVAQLVRRAERAGFKAIALTVDTPRLGRREADIKNRFVLPPFLTLKNF 183

Query: 195 ADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQRA 254
             + D  ++   A  SGL+SYVA  ID SL+W D+AWL++IT LPIL+KGV+TAEDA+ A
Sbjct: 184 EGI-DLGKMDK-ANDSGLSSYVAGQIDRSLSWKDVAWLQTITSLPILVKGVITAEDARLA 241

Query: 255 LQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALALG 314
           +Q+GA GI +SNHGARQLD V ATI  LEEV ++ +GRIPVF+D GVRRGTDV KALALG
Sbjct: 242 VQHGAAGIIVSNHGARQLDYVPATIMALEEVVKAAQGRIPVFLDGGVRRGTDVFKALALG 301

Query: 315 ADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLVVRD 370
           A  V IGRP+V+ LA +GE GV ++L +++DEF+L M L GC+ + +I R  +  D
Sbjct: 302 AAGVFIGRPVVFSLAAEGEAGVKKVLQMMRDEFELTMALSGCRSLKEISRSHIAAD 357

gb|AAO17067.1| glycolate oxidase [Zantedeschia aethiopica]
(367 aa)

Score: 425 bits (1092), Expect: 1.42608e-117
Length: 357, Idn/Pos/Gap = 212/281/3 (59%/78%/0%)

Query:  15 NLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQV  74
           N++EY   AK +LP MVY YYASGA+D+ TL++N  AF R+ FRPR+LIDV+++D+T  V
Sbjct:   5 NVSEYEAVAKDKLPKMVYDYYASGAEDQWTLKENRNAFSRILFRPRILIDVTKIDMTTTV  64

Query:  75 MGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLP 134
           +G  +S P+M+APTAMQ+MAH +GE ATARA +  GT+M LSSWAT+S+E+VA+  PG+ 
Sbjct:  65 LGYKISMPIMIAPTAMQKMAHLDGEYATARAASAAGTIMTLSSWATSSVEEVASTGPGI- 123

Query: 135 KFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANF 194
           +FFQLYVYKDR +  +LVRRAERAGF+AIALTVDTP+LGRRE+DI+N+F LPPHL+L NF
Sbjct: 124 RFFQLYVYKDRNVVAQLVRRAERAGFKAIALTVDTPRLGRRESDIKNRFTLPPHLTLKNF 183

Query: 195 ADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQRA 254
             + D  ++   +  SGLASYVA  ID SL+W D+ WL++IT +PIL+KGV+TAED + A
Sbjct: 184 EGL-DLGKMDK-SNDSGLASYVAGQIDRSLSWKDVKWLQTITSMPILVKGVMTAEDTRLA 241

Query: 255 LQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALALG 314
           +Q GA GI +SNHGARQLD V ATI CLEEV ++ +GR+PVF+D GVRRGTDV KALALG
Sbjct: 242 VQAGAAGIIVSNHGARQLDYVPATISCLEEVVKAAQGRVPVFLDGGVRRGTDVFKALALG 301

Query: 315 ADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLVVRDA 371
           A  + IGRP+V+ LA +GE GV ++L +L++EF+L M L GC  + DI R+ ++ + 
Sbjct: 302 ASGIFIGRPVVFSLAAEGEAGVRKVLQMLREEFELTMALSGCLSLKDITRNHILTEG 358

gb|AAL16258.1| AT3g14420/MOA2_2 [Arabidopsis thaliana]
(367 aa)

Score: 424 bits (1090), Expect: 2.02459e-117
Length: 360, Idn/Pos/Gap = 215/282/3 (59%/78%/0%)

Query:  15 NLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQV  74
           N+ EY   AK +LP MVY YYASGA+D+ TL++N  AF R+ FRPR+LID S++D+T  V
Sbjct:   5 NVTEYDAIAKQKLPKMVYDYYASGAEDQWTLQENRNAFARILFRPRILIDASKIDMTTTV  64

Query:  75 MGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLP 134
           +G  +S P+MVAPTAMQ+MAHP+GE ATARA +  GT+M LSSWAT+S+E+VA+  PG+ 
Sbjct:  65 LGFKISMPIMVAPTAMQKMAHPDGEYATARAASAAGTIMTLSSWATSSVEEVASTGPGI- 123

Query: 135 KFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANF 194
           +FFQLYVYK+R + E+LVRRAERAGF+AIALTVDTP+LGRRE+DI+N+F LPP+L+L NF
Sbjct: 124 RFFQLYVYKNRNVVEQLVRRAERAGFKAIALTVDTPRLGRRESDIKNRFTLPPNLTLKNF 183

Query: 195 ADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQRA 254
             + D  ++   A  SGLASYVA  ID +L+W D+ WL++IT+LPIL+KGV+T EDA+ A
Sbjct: 184 EGL-DLGKMDE-ANDSGLASYVAGQIDRTLSWKDVQWLQTITKLPILVKGVLTGEDARIA 241

Query: 255 LQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALALG 314
           +Q GA GI +SNHGARQLD V ATI  LEEV ++ +GRIPVF+D GVRRGTDV KALALG
Sbjct: 242 IQAGAAGIIVSNHGARQLDYVPATISALEEVVKATQGRIPVFLDGGVRRGTDVFKALALG 301

Query: 315 ADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLVVRDAFAP 374
           A  + IGRP+V+ LA +GE GV ++L +L+DEF+L M L GC+ + +I R+ +  +   P
Sbjct: 302 ASGIFIGRPVVFSLAAEGEAGVRKVLQMLRDEFELTMALSGCRSLKEISRNHITTEWDTP 361

sp|P05414|GOX_SPIOL (S)-2-hydroxy-acid oxidase, peroxisomal (Glycolate oxidase) (GOX) (Short chain alpha-hydroxy acid oxidase)
gb|AAA34030.1| glycolate oxidase (EC 1.1.3.15)
pdb|1GOX| Glycolate Oxidase (E.C.1.1.3.1)
(369 aa)

Score: 423 bits (1088), Expect: 3.54096e-117
Length: 360, Idn/Pos/Gap = 218/280/3 (60%/77%/0%)

Query:  15 NLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQV  74
           N+ EY   AK +LP MVY YYASGA+D+ TL +N  AF R+ FRPR+LIDV+ +D+T  +
Sbjct:   5 NVNEYEAIAKQKLPKMVYDYYASGAEDQWTLAENRNAFSRILFRPRILIDVTNIDMTTTI  64

Query:  75 MGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLP 134
           +G  +S P+M+APTAMQ+MAHPEGE ATARA +  GT+M LSSWAT+S+E+VA+  PG+ 
Sbjct:  65 LGFKISMPIMIAPTAMQKMAHPEGEYATARAASAAGTIMTLSSWATSSVEEVASTGPGI- 123

Query: 135 KFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANF 194
           +FFQLYVYKDR +  +LVRRAERAGF+AIALTVDTP+LGRREADI+N+F LPP L+L NF
Sbjct: 124 RFFQLYVYKDRNVVAQLVRRAERAGFKAIALTVDTPRLGRREADIKNRFVLPPFLTLKNF 183

Query: 195 ADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQRA 254
             + D  ++   A  SGL+SYVA  ID SL+W D+AWL++IT LPIL+KGV+TAEDA+ A
Sbjct: 184 EGI-DLGKMDK-ANDSGLSSYVAGQIDRSLSWKDVAWLQTITSLPILVKGVITAEDARLA 241

Query: 255 LQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALALG 314
           +Q+GA GI +SNHGARQLD V ATI  LEEV ++ +GRIPVF+D GVRRGTDV KALALG
Sbjct: 242 VQHGAAGIIVSNHGARQLDYVPATIMALEEVVKAAQGRIPVFLDGGVRRGTDVFKALALG 301

Query: 315 ADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLVVRDAFAP 374
           A  V IGRP+V+ LA +GE GV ++L +++DEF+L M L GC+ + +I R  +  D   P
Sbjct: 302 AAGVFIGRPVVFSLAAEGEAGVKKVLQMMRDEFELTMALSGCRSLKEISRSHIAADWDGP 361

pdb|1GYL|B Chain B, Glycolate Oxidase (E.C.1.1.3.15) Mutant With Tyr 24 Replaced By Phe (Y24f)
pdb|1GYL|A Chain A, Glycolate Oxidase (E.C.1.1.3.15) Mutant With Tyr 24 Replaced By Phe (Y24f)
(369 aa)

Score: 422 bits (1084), Expect: 9.71812e-117
Length: 360, Idn/Pos/Gap = 217/280/3 (60%/77%/0%)

Query:  15 NLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQV  74
           N+ EY   AK +LP MVY +YASGA+D+ TL +N  AF R+ FRPR+LIDV+ +D+T  +
Sbjct:   5 NVNEYEAIAKQKLPKMVYDFYASGAEDQWTLAENRNAFSRILFRPRILIDVTNIDMTTTI  64

Query:  75 MGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLP 134
           +G  +S P+M+APTAMQ+MAHPEGE ATARA +  GT+M LSSWAT+S+E+VA+  PG+ 
Sbjct:  65 LGFKISMPIMIAPTAMQKMAHPEGEYATARAASAAGTIMTLSSWATSSVEEVASTGPGI- 123

Query: 135 KFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANF 194
           +FFQLYVYKDR +  +LVRRAERAGF+AIALTVDTP+LGRREADI+N+F LPP L+L NF
Sbjct: 124 RFFQLYVYKDRNVVAQLVRRAERAGFKAIALTVDTPRLGRREADIKNRFVLPPFLTLKNF 183

Query: 195 ADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQRA 254
             + D  ++   A  SGL+SYVA  ID SL+W D+AWL++IT LPIL+KGV+TAEDA+ A
Sbjct: 184 EGI-DLGKMDK-ANDSGLSSYVAGQIDRSLSWKDVAWLQTITSLPILVKGVITAEDARLA 241

Query: 255 LQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALALG 314
           +Q+GA GI +SNHGARQLD V ATI  LEEV ++ +GRIPVF+D GVRRGTDV KALALG
Sbjct: 242 VQHGAAGIIVSNHGARQLDYVPATIMALEEVVKAAQGRIPVFLDGGVRRGTDVFKALALG 301

Query: 315 ADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLVVRDAFAP 374
           A  V IGRP+V+ LA +GE GV ++L +++DEF+L M L GC+ + +I R  +  D   P
Sbjct: 302 AAGVFIGRPVVFSLAAEGEAGVKKVLQMMRDEFELTMALSGCRSLKEISRSHIAADWDGP 361

ref|XP_476669.1| putative glycolate oxidase [Oryza sativa (japonica cultivar-group)]
ref|XP_506164.1| PREDICTED B1364A02.11-1 gene product [Oryza sativa (japonica cultivar-group)]
dbj|BAC84719.1| putative glycolate oxidase [Oryza sativa (japonica cultivar-group)]
dbj|BAD31578.1| putative (S)-2-hydroxy-acid oxidase [Oryza sativa (japonica cultivar-group)]
(369 aa)

Score: 421 bits (1083), Expect: 1.33438e-116
Length: 357, Idn/Pos/Gap = 216/279/3 (60%/78%/0%)

Query:  15 NLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQV  74
           N+ EY   AK +LP M+Y YYASGA+DE TL++N EAF R+ FRPR+LIDVS++D+   V
Sbjct:   6 NVTEYQAIAKQKLPKMIYDYYASGAEDEWTLQENREAFARILFRPRILIDVSKIDMATTV  65

Query:  75 MGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLP 134
           +G  +S P+M+AP+AMQ+MAHP+GE ATARA +  GT+M LSSWAT+S+E+VA+  PG+ 
Sbjct:  66 LGFKISMPIMIAPSAMQKMAHPDGEYATARAASAAGTIMTLSSWATSSVEEVASTGPGI- 124

Query: 135 KFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANF 194
           +FFQLYVYKDR + E+LVRRAERAGF+AIALTVDTP+LGRREADI+N+F LPP L+L NF
Sbjct: 125 RFFQLYVYKDRRVVEQLVRRAERAGFKAIALTVDTPRLGRREADIKNRFVLPPFLTLKNF 184

Query: 195 ADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQRA 254
             ++     +  A  SGLASYVA  ID +L+W D+ WL++IT LPIL+KGV+TAED + A
Sbjct: 185 EGLELGKMDQ--ASDSGLASYVAGQIDRTLSWKDVKWLQTITTLPILVKGVITAEDTRLA 242

Query: 255 LQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALALG 314
           ++ GA GI +SNHGARQLD V ATI  LEEV ++ RG++PVF+D GVRRGTDV KALALG
Sbjct: 243 VENGAAGIIVSNHGARQLDYVPATISALEEVVKAARGQLPVFLDGGVRRGTDVFKALALG 302

Query: 315 ADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLVVRDA 371
           A  V IGRP+V+ LA  GE GV  +L +L+DEF+L M L GC  ++DI R+ V+ +A
Sbjct: 303 AAGVFIGRPVVFSLAAAGEAGVRNVLQMLRDEFELTMALSGCTSLADITRNHVITEA 359

pir||T10242 (S)-2-hydroxy-acid oxidase (EC 1.1.3.15) - cucurbit
dbj|BAA03131.1| glycolate oxidase [Cucurbita cv. Kurokawa Amakuri]
(367 aa)

Score: 412 bits (1060), Expect: 6.51666e-114
Length: 360, Idn/Pos/Gap = 214/278/3 (59%/77%/0%)

Query:  15 NLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQV  74
           N+ EY   AK +LP MVY YYASGA+D+  L++N  AF R+ FRPR+LIDVS++D++  V
Sbjct:   5 NVTEYEAIAKEKLPKMVYDYYASGAEDQWALKENRNAFSRILFRPRILIDVSKIDMSTTV  64

Query:  75 MGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLP 134
           +G  +S P+M+APTAMQ+MAHPEGE ATARA +  GT   LSSWAT+S+E+VA+  PG+ 
Sbjct:  65 LGFKISMPIMIAPTAMQKMAHPEGEYATARAASAAGTTTTLSSWATSSVEEVASTGPGI- 123

Query: 135 KFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANF 194
           +FFQLYVYKDR +  +LVRRAE+AGF+AIALTVDTP+LGRREADI+N+F LPP L+L NF
Sbjct: 124 RFFQLYVYKDRNVVAQLVRRAEKAGFKAIALTVDTPRLGRREADIKNRFTLPPFLTLKNF 183

Query: 195 ADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQRA 254
             + D  ++   A  SGLASYVA  ID +L+W D+ WL++IT+LPIL+KGV+TAED + A
Sbjct: 184 EGL-DLGKMDQ-ADDSGLASYVAGQIDRTLSWQDVKWLQTITKLPILVKGVLTAEDTRIA 241

Query: 255 LQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALALG 314
           +Q GA GI +SNHGARQLD V ATI  LEEV ++ RG +PVF+D GVRRGTDV KALALG
Sbjct: 242 VQSGAAGIIVSNHGARQLDYVPATIMALEEVVKAARGEVPVFLDGGVRRGTDVFKALALG 301

Query: 315 ADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLVVRDAFAP 374
           A  + IGRP+V+ LA +GE GV ++L +L+DEF+L M L GC+ + +I R+ +V D   P
Sbjct: 302 ASGIFIGRPVVFSLAAEGEAGVRKVLQMLRDEFELIMALSGCRSLQEITRNHIVADWDTP 361

gb|AAB82143.1| glycolate oxidase [Oryza sativa]
pir||T02150 probable (S)-2-hydroxy-acid oxidase (EC 1.1.3.15), peroxisomal - rice
(369 aa)

Score: 394 bits (1011), Expect: 3.08072e-108
Length: 357, Idn/Pos/Gap = 200/265/3 (56%/74%/0%)

Query:  15 NLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQV  74
           N+ EY   A   LP M+Y YY+SGA+D+ TL++N EAF  + FRPR+LIDVS++D++  V
Sbjct:   6 NVMEYQAIANQNLPKMIYDYYSSGAEDDWTLKENREAFSAILFRPRILIDVSKIDMSATV  65

Query:  75 MGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLP 134
           +G  +S P+M+AP+AMQ+MAHP+GE ATARA +  GT+M LSSWAT+S+E+VA+  PG P
Sbjct:  66 LGFKISMPIMIAPSAMQKMAHPDGEYATARAASAAGTIMTLSSWATSSVEEVASTGPGNP 125

Query: 135 KFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANF 194
            F  LY+ KDR + E LV++ +RAGF+AIALTVD P+LGRRE DI+N+F LPP+L+L  F
Sbjct: 126 -FLHLYLCKDRNVVEHLVKKTKRAGFKAIALTVDAPRLGRRETDIKNRFVLPPYLTLKKF 184

Query: 195 ADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQRA 254
             + D  ++   +  SGLASYVA  ID +L W D+ WL+SIT LPIL+KGV+TAEDA+ A
Sbjct: 185 EGL-DLPEMDK-SNDSGLASYVAGQIDRALTWKDVKWLQSITSLPILVKGVITAEDAKLA 242

Query: 255 LQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALALG 314
           +  GA GI +SNHGARQLD V ATI  LEEV  +  GRIPV++D GVRRGTDV KALALG
Sbjct: 243 VHSGAAGIIVSNHGARQLDYVPATISALEEVVTAAAGRIPVYLDGGVRRGTDVFKALALG 302

Query: 315 ADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLVVRDA 371
           A  V IG+P+V+ LA +G+ GV  LL ++++EF+L M   GC  ++DI R  +  DA
Sbjct: 303 AAGVFIGKPVVFALAAEGKAGVRNLLRMMREEFELTMAFSGCTSLADITRAHIYTDA 359

emb|CAG06223.1| unnamed protein product [Tetraodon nigroviridis]
(373 aa)

Score: 388 bits (996), Expect: 2.01418e-106
Length: 368, Idn/Pos/Gap = 199/263/5 (54%/71%/1%)

Query:  10 ATQPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVD  69
           ++Q + ++++   A+  LP  VY YY SGADD+ TL+DN  AF R    PRVL +VS VD
Sbjct:   2 SSQRVCVSDFEEEARKVLPKAVYDYYRSGADDQNTLKDNIAAFDRWYLVPRVLRNVSTVD  61

Query:  70 ITKQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAH 129
           ++  V+G  LS P+ VA TAMQRMAHP+GE ATA+A   +GT M LSSWAT+++E+V A 
Sbjct:  62 LSVCVLGEKLSMPVCVAATAMQRMAHPDGETATAKACQAVGTGMMLSSWATSTIEEVMAA 121

Query: 130 VPGLPK-----FFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQ 184
           +          + QLY+YKDR +T  LVRRAE+AG++AI +TVDTP LG+R  D+RN F+
Sbjct: 122 MTSTTGTEGVLWLQLYIYKDRELTLSLVRRAEQAGYKAIFVTVDTPYLGKRRDDMRNHFK 181

Query: 185 LPPHLSLANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKG 244
           LP HLSL+NF+        +     SGLA YVA  ID +L W+DIAWLKS T LP+++KG
Sbjct: 182 LPQHLSLSNFSTASLAFSEESYGNDSGLAVYVAKAIDPTLCWDDIAWLKSHTCLPVIVKG 241

Query: 245 VVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRG 304
           V+  +DA +A+ YG DGI +SNHGARQLDGV AT+D LEEV ++V+GR  V++D GVRRG
Sbjct: 242 VLNGDDAAKAVTYGIDGILVSNHGARQLDGVPATLDVLEEVVKAVQGRCDVYMDGGVRRG 301

Query: 305 TDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRR 364
           TDV+KALALGA AV IGRP++WGL+  GE+GV  +L L+K E +LAM L GC+ VS++ R
Sbjct: 302 TDVLKALALGAKAVFIGRPVLWGLSCQGEQGVIEVLELIKQELRLAMALSGCRSVSEVSR 361

Query: 365 DLVVRDAF 372
            +V R  F
Sbjct: 362 SIVRRMEF 369

ref|NP_850585.1| (S)-2-hydroxy-acid oxidase, peroxisomal, putative / glycolate oxidase, putative / short chain alpha-hydroxy acid oxidase, putative [Arabidopsis thaliana]
(366 aa)

Score: 382 bits (982), Expect: 7.16174e-105
Length: 318, Idn/Pos/Gap = 193/253/3 (60%/79%/0%)

Query:  57 FRPRVLIDVSRVDITKQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLS 116
           FRPR+LIDVS++D+T  V+G  +S P+MVAPTAMQ+MAHP+GE ATARA +  GT+M LS
Sbjct:  46 FRPRILIDVSKIDMTTTVLGFKISMPIMVAPTAMQKMAHPDGEYATARAASAAGTIMTLS 105

Query: 117 SWATTSLEDVAAHVPGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRRE 176
           SWAT+S+E+VA+  PG+ +FFQLYVYK+R + E+LVRRAERAGF+AIALTVDTP+LGRRE
Sbjct: 106 SWATSSVEEVASTGPGI-RFFQLYVYKNRNVVEQLVRRAERAGFKAIALTVDTPRLGRRE 164

Query: 177 ADIRNQFQLPPHLSLANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSIT 236
           +DI+N+F LPP+L+L NF  + D  ++   A  SGLASYVA  ID +L+W D+ WL++IT
Sbjct: 165 SDIKNRFTLPPNLTLKNFEGL-DLGKMDE-ANDSGLASYVAGQIDRTLSWKDVQWLQTIT 222

Query: 237 RLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVF 296
           +LPIL+KGV+T EDA+ A+Q GA GI +SNHGARQLD V ATI  LEEV ++ +GRIPVF
Sbjct: 223 KLPILVKGVLTGEDARIAIQAGAAGIIVSNHGARQLDYVPATISALEEVVKATQGRIPVF 282

Query: 297 IDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGC 356
           +D GVRRGTDV KALALGA  + IGRP+V+ LA +GE GV ++L +L+DEF+L M L GC
Sbjct: 283 LDGGVRRGTDVFKALALGASGIFIGRPVVFSLAAEGEAGVRKVLQMLRDEFELTMALSGC 342

Query: 357 QKVSDIRRDLVVRDAFAP 374
           + + +I R+ +  +   P
Sbjct: 343 RSLKEISRNHITTEWDTP 360

gb|EAL61528.1| hypothetical protein DDB0184082 [Dictyostelium discoideum]
(388 aa)

Score: 382 bits (981), Expect: 9.5906e-105
Length: 354, Idn/Pos/Gap = 182/253/6 (51%/71%/1%)

Query:  14 LNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQ  73
           ++++E H  AK  LP M Y YYASG++D+ TL +NE AF R++  PR L+DVS+V+   +
Sbjct:  32 VSVSELHEEAKRLLPKMAYDYYASGSNDQITLAENENAFSRIKLVPRSLVDVSKVNTKTR  91

Query:  74 VMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGL 133
           + G D+S P+++AP AMQRMA   GEL T  A     T+M LSS +TTS+ED+++   G 
Sbjct:  92 IFGRDISTPILIAPWAMQRMASQRGELDTVEASKEFNTIMTLSSLSTTSVEDLSSATNGN 151

Query: 134 PKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLAN 193
           P +FQLYV+KDR ++E LV+RAE  G+ A+ LTVDTP LG+R AD +N F+LP  LSL  
Sbjct: 152 PGWFQLYVFKDRKVSEELVKRAESIGYSALVLTVDTPFLGKRTADFKNSFKLPNGLSLKI 211

Query: 194 FADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQR 253
           F  +   + + GG     L  Y+A++ID SL WND+ WLKSIT+LPIL+KG++  +DA+ 
Sbjct: 212 FEKLM-LSNLDGG-----LNQYIATMIDPSLTWNDLKWLKSITKLPILVKGIMCPKDAEL 265

Query: 254 ALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALAL 313
           ALQYGADGI +SNHG RQLD   +TI+ L  +++ VRGR+P+ +D G+RRGTDV+KALA 
Sbjct: 266 ALQYGADGIIVSNHGGRQLDTCPSTIEVLPYISKVVRGRVPLILDGGIRRGTDVLKALAF 325

Query: 314 GADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLV 367
           GA+AV IGRPI+WGL+  G++GV ++L+LL  E +LAM L G   +SDI   ++
Sbjct: 326 GANAVCIGRPIIWGLSTGGKDGVLKVLNLLNSELQLAMALTGITNISDINNSII 379

emb|CAB57329.1| hypothetical protein [Homo sapiens]
emb|CAC34364.1| GD:HAO1 [Homo sapiens]
gb|AAF63219.1| glycolate oxidase [Homo sapiens]
gb|AAF40199.1| short chain 2-hydroxy acid oxidase HAOX1 [Homo sapiens]
ref|NP_060015.1| hydroxyacid oxidase 1 [Homo sapiens]
sp|Q9UJM8|HAO1_HUMAN Hydroxyacid oxidase 1 (HAOX1) (Glycolate oxidase) (GOX)
(370 aa)

Score: 381 bits (979), Expect: 1.88522e-104
Length: 357, Idn/Pos/Gap = 189/257/1 (52%/71%/0%)

Query:  18 EYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGI  77
           +Y   AK+ LP  +Y YY SGA+DE+TL DN  AF R +  PR+L +V+  D++  V+G 
Sbjct:  10 DYEQHAKSVLPKSIYDYYRSGANDEETLADNIAAFSRWKLYPRMLRNVAETDLSTSVLGQ  69

Query:  78 DLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFF 137
            +S P+ V  TAMQRMAH +GELAT RA   +GT M LSSWAT+S+E+VA   P   ++ 
Sbjct:  70 RVSMPICVGATAMQRMAHVDGELATVRACQSLGTGMMLSSWATSSIEEVAEAGPEALRWL 129

Query: 138 QLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANF-AD 196
           QLY+YKDR +T++LVR+AE+ G++AI +TVDTP LG R  D+RN+F+LPP L + NF   
Sbjct: 130 QLYIYKDREVTKKLVRQAEKMGYKAIFVTVDTPYLGNRLDDVRNRFKLPPQLRMKNFETS 189

Query: 197 MKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQRALQ 256
              F+  +     SGLA+YVA  ID S++W DI WL+ +T LPI+ KG++  +DA+ A++
Sbjct: 190 TLSFSPEENFGDDSGLAAYVAKAIDPSISWEDIKWLRRLTSLPIVAKGILRGDDAREAVK 249

Query: 257 YGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALALGAD 316
           +G +GI +SNHGARQLDGV ATID L E+ ++V G++ VF+D GVR+GTDV+KALALGA 
Sbjct: 250 HGLNGILVSNHGARQLDGVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAK 309

Query: 317 AVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLVVRDAFA 373
           AV +GRPIVWGLA  GE+GV  +L +LK+EF+LAM L GCQ V  I + LV ++  A
Sbjct: 310 AVFVGRPIVWGLAFQGEKGVQDVLEILKEEFRLAMALSGCQNVKVIDKTLVRKNPLA 366

dbj|BAA82872.1| a liver-specific gene similar to the plant glycolate oxidase [Homo sapiens]
(370 aa)

Score: 380 bits (977), Expect: 3.05867e-104
Length: 357, Idn/Pos/Gap = 189/257/1 (52%/71%/0%)

Query:  18 EYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGI  77
           +Y   AK+ LP  +Y YY SGA+DE+TL DN  AF R +  PR+L +V+  D++  V+G 
Sbjct:  10 DYEQHAKSVLPKSIYDYYRSGANDEETLADNIAAFSRWKLYPRMLRNVAETDLSTSVLGQ  69

Query:  78 DLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFF 137
            +S P+ V  TAMQRMAH +GELAT RA   +GT M LSSWAT+S+E+VA   P   ++ 
Sbjct:  70 RVSMPICVGATAMQRMAHVDGELATVRACQSLGTGMMLSSWATSSIEEVAEAGPEALRWL 129

Query: 138 QLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANF-AD 196
           QLY+YKDR +T++LVR+AE+ G++AI +TVDTP LG R  D+RN+F+LPP L + NF   
Sbjct: 130 QLYIYKDREVTKKLVRQAEKMGYKAIFVTVDTPYLGNRLDDVRNRFKLPPQLRMKNFETS 189

Query: 197 MKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQRALQ 256
              F+  +     SGLA+YVA  ID S++W DI WL+ +T LPI+ KG++  +DA+ A++
Sbjct: 190 TLSFSPEENFGDDSGLAAYVAKAIDPSISWEDIKWLRRLTSLPIVAKGILRGDDAREAVK 249

Query: 257 YGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALALGAD 316
           +G +GI +SNHGARQLDGV ATID L E+ ++V G++ VF+D GVR+GTDV+KALALGA 
Sbjct: 250 HGLNGILVSNHGARQLDGVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAK 309

Query: 317 AVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLVVRDAFA 373
           AV +GRPIVWGLA  GE+GV  +L +LK+EF+LAM L GCQ V  I + LV ++  A
Sbjct: 310 AVFVGRPIVWGLAFQGEKGVQDVLXILKEEFRLAMALSGCQNVKVIDKTLVRKNPLA 366

ref|XP_230613.2| PREDICTED: similar to glycolate oxidase; short-chain alpha-hydroxy acid oxidase [Rattus norvegicus]
(370 aa)

Score: 378 bits (970), Expect: 1.9661e-103
Length: 360, Idn/Pos/Gap = 191/260/3 (53%/72%/0%)

Query:  16 LAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVM  75
           +++Y   A+  L   VY YY SGA+D++TL DN  AF R +  PR+L +V+ +D++  V+
Sbjct:   8 ISDYEQHARTVLQKSVYDYYKSGANDQETLADNIRAFSRWKLYPRMLRNVADIDLSTSVL  67

Query:  76 GIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPK 135
           G  +S P+ V  TAMQ MAH +GELAT RA   +GT M LSSWAT+S+E+VA   P   +
Sbjct:  68 GQRVSMPICVGATAMQCMAHVDGELATVRACQTMGTGMMLSSWATSSIEEVAEAGPEALR 127

Query: 136 FFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANFA 195
           + QLY+YKDR ++ +LV+RAE+ G++AI +TVDTP LG R  D+RN+F+LPP L + NF 
Sbjct: 128 WMQLYIYKDREVSSQLVKRAEQMGYKAIFVTVDTPYLGNRFDDVRNRFKLPPQLRMKNF- 186

Query: 196 DMKDFA-QVKGGAG-ASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQR 253
           +  D A   KG  G  SGLA YVA  ID SL+W+DI WL+ +T LPI++KG++  +DAQ 
Sbjct: 187 ETNDLAFSPKGNFGDNSGLAEYVAQAIDPSLSWDDIKWLRRLTSLPIVVKGILRGDDAQE 246

Query: 254 ALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALAL 313
           A+++G DGI +SNHGARQLDGV ATID L E+ ++V G++ VF+D GVR+GTDV+KALAL
Sbjct: 247 AVKHGVDGILVSNHGARQLDGVPATIDALPEIVEAVEGKVEVFLDGGVRKGTDVLKALAL 306

Query: 314 GADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLVVRDAFA 373
           GA AV +GRPI+WGLA  GE+GV  +L +LK+EF+LAM L GCQ V  I + LV ++  A
Sbjct: 307 GARAVFVGRPIIWGLAFQGEKGVQDVLEILKEEFRLAMALSGCQNVKVIDKTLVRKNPLA 366

ref|NP_034533.1| hydroxyacid oxidase 1, liver [Mus musculus]
gb|AAD25332.1| glycolate oxidase; short-chain alpha-hydroxy acid oxidase [Mus musculus]
sp|Q9WU19|HAO1_MOUSE Hydroxyacid oxidase 1 (HAOX1) (Glycolate oxidase) (GOX)
(370 aa)

Score: 377 bits (967), Expect: 3.70683e-103
Length: 360, Idn/Pos/Gap = 189/261/3 (52%/72%/0%)

Query:  16 LAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVM  75
           +++Y    ++ L   VY YY SGA+D++TL DN +AF R +  PR+L +V+ +D++  V+
Sbjct:   8 ISDYEQHVRSVLQKSVYDYYRSGANDQETLADNIQAFSRWKLYPRMLRNVADIDLSTSVL  67

Query:  76 GIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPK 135
           G  +S P+ V  TAMQ MAH +GELAT RA   +GT M LSSWAT+S+E+VA   P   +
Sbjct:  68 GQRVSMPICVGATAMQCMAHVDGELATVRACQTMGTGMMLSSWATSSIEEVAEAGPEALR 127

Query: 136 FFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANFA 195
           + QLY+YKDR I+ ++V+RAE+ G++AI +TVDTP LG R  D+RN+F+LPP L + NF 
Sbjct: 128 WMQLYIYKDREISRQIVKRAEKQGYKAIFVTVDTPYLGNRIDDVRNRFKLPPQLRMKNF- 186

Query: 196 DMKDFA-QVKGGAG-ASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQR 253
           +  D A   KG  G  SGLA YVA  ID SL+W+DI WL+ +T LPI++KG++  +DA+ 
Sbjct: 187 ETNDLAFSPKGNFGDNSGLAEYVAQAIDPSLSWDDITWLRRLTSLPIVVKGILRGDDAKE 246

Query: 254 ALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALAL 313
           A+++G DGI +SNHGARQLDGV ATID L E+ ++V G++ VF+D GVR+GTDV+KALAL
Sbjct: 247 AVKHGVDGILVSNHGARQLDGVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALAL 306

Query: 314 GADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLVVRDAFA 373
           GA AV +GRPI+WGLA  GE+GV  +L +LK+EF+LAM L GCQ V  I + LV ++  A
Sbjct: 307 GAKAVFVGRPIIWGLAFQGEKGVQDVLEILKEEFRLAMALSGCQNVKVIDKTLVRKNPLA 366

dbj|BAB02977.1| glycolate oxidase [Arabidopsis thaliana]
gb|AAO22568.1| putative glycolate oxidase [Arabidopsis thaliana]
ref|NP_188029.1| (S)-2-hydroxy-acid oxidase, peroxisomal, putative / glycolate oxidase, putative / short chain alpha-hydroxy acid oxidase, putative [Arabidopsis thaliana]
(363 aa)

Score: 368 bits (944), Expect: 1.93524e-100
Length: 356, Idn/Pos/Gap = 188/262/6 (52%/73%/1%)

Query:  12 QPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDIT  71
           Q +N+ E+   AK  LP M Y +Y  GA+D+ TL +N +AFRR+ FRPRVL+DVS +D++
Sbjct:   3 QIVNVDEFQELAKQALPKMYYDFYNGGAEDQHTLNENVQAFRRIMFRPRVLVDVSNIDMS  62

Query:  72 KQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVP 131
             ++G  +S P+M+APTAM ++AHP+GE+ATA+A A   T+M +S  +T ++E+VA+   
Sbjct:  63 TSMLGYPISAPIMIAPTAMHKLAHPKGEIATAKAAAACNTIMIVSFMSTCTIEEVASSCN 122

Query: 132 GLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSL 191
            + +F Q+YVYK R +T ++V+RAE+AGF+AI LTVD P+LGRREADI+N+   P    L
Sbjct: 123 AV-RFLQIYVYKRRDVTAQIVKRAEKAGFKAIVLTVDVPRLGRREADIKNKMISP---QL 178

Query: 192 ANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDA 251
            NF  +    +V+   G SG+ ++ +S  DASL+W DI WL+SIT+LPIL+KG++T EDA
Sbjct: 179 KNFEGLVS-TEVRPNEG-SGVEAFASSAFDASLSWKDIEWLRSITKLPILVKGLLTREDA 236

Query: 252 QRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKAL 311
            +A++ G DGI +SNHGARQLD   ATI  LEEV  +V+GRIPV +D GVRRGTDV KAL
Sbjct: 237 LKAVEAGVDGIVVSNHGARQLDYSPATITVLEEVVHAVKGRIPVLLDGGVRRGTDVFKAL 296

Query: 312 ALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLV 367
           ALGA AVLIGRPIV+GLA  GE+GV +++ +LK+EF++ M L GC  + D+ R+ V
Sbjct: 297 ALGAQAVLIGRPIVYGLAAKGEDGVKKVIDMLKNEFEITMALSGCPTIDDVTRNHV 352

gb|AAM61594.1| glycolate oxidase, putative [Arabidopsis thaliana]
(363 aa)

Score: 365 bits (938), Expect: 9.60451e-100
Length: 356, Idn/Pos/Gap = 187/260/6 (52%/73%/1%)

Query:  12 QPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDIT  71
           Q +N+ E+   AK  LP M Y +Y  GA+D+ TL +N +AFRR+ FRPRVL+DVS +D++
Sbjct:   3 QIVNVDEFQELAKQALPKMYYDFYNGGAEDQHTLNENVQAFRRIMFRPRVLVDVSNIDMS  62

Query:  72 KQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVP 131
             ++G  +S P+M+APTAM ++AHP+GE+ATA+A A   T+M +   +T ++E+VA+   
Sbjct:  63 TSILGYPISAPIMIAPTAMHKLAHPKGEIATAKAAAACNTIMIVPFMSTCTIEEVASSCN 122

Query: 132 GLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSL 191
            + +F Q+YVYK R +T ++V+RAE+AGF+AI LTVD P+LGRREADI+N+   P    L
Sbjct: 123 AV-RFLQIYVYKRRDVTAQIVKRAEKAGFKAIVLTVDVPRLGRREADIKNKMISP---QL 178

Query: 192 ANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDA 251
            NF  +    +V+   G SG+ ++ +S  DASL+W DI WL+SIT+LPIL+KG++T EDA
Sbjct: 179 KNFEGLVS-TEVRPNEG-SGVEAFASSAFDASLSWKDIEWLRSITKLPILVKGLLTREDA 236

Query: 252 QRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKAL 311
            +A++ G DGI +SNHGARQLD   ATI  LEEV   V+GRIPV +D GVRRGTDV KAL
Sbjct: 237 LKAVEAGVDGIVVSNHGARQLDYSPATITVLEEVVHVVKGRIPVLLDGGVRRGTDVFKAL 296

Query: 312 ALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLV 367
           ALGA AVLIGRPIV+GLA  GE+GV +++ +LK+EF++ M L GC  + D+ R+ V
Sbjct: 297 ALGAQAVLIGRPIVYGLAAKGEDGVKKVIDMLKNEFEITMALSGCPTIDDVTRNHV 352

ref|NP_188031.1| (S)-2-hydroxy-acid oxidase, peroxisomal, putative / glycolate oxidase, putative / short chain alpha-hydroxy acid oxidase, putative [Arabidopsis thaliana]
(363 aa)

Score: 364 bits (934), Expect: 2.79449e-99
Length: 356, Idn/Pos/Gap = 184/255/6 (51%/71%/1%)

Query:  12 QPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDIT  71
           Q +N+ E+   AK  LP M Y +Y  GA+D+ TL +N +AFRR+ FRPRVL+DVS++D++
Sbjct:   3 QIVNVDEFQELAKQALPKMYYDFYNGGAEDQHTLNENVQAFRRIMFRPRVLVDVSKIDMS  62

Query:  72 KQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVP 131
            +++G  +S P+M+APT   ++AHPEGE ATA+A A   T+M +S  ++ + E++A+   
Sbjct:  63 TKILGYPISAPIMIAPTGNHKLAHPEGETATAKAAAACNTIMIVSYMSSCTFEEIASSCN 122

Query: 132 GLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSL 191
            + +F Q+YVYK R IT ++V+RAE+AGF+AI LTVD P+LGRREADI+N+   P    L
Sbjct: 123 AV-RFLQIYVYKRRDITAQVVKRAEKAGFKAIVLTVDVPRLGRREADIKNKMISP---QL 178

Query: 192 ANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDA 251
            NF  +  F+     +  SG+ ++ +   DAS +W DI WL+SIT LPIL+KG++T EDA
Sbjct: 179 KNFEGL--FSTEVRPSKGSGVQAFASRAFDASFSWKDIEWLRSITELPILVKGILTREDA 236

Query: 252 QRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKAL 311
            +A++ G DGI +SNHG RQLD   ATI  LEEV Q VRGRIPV +D GVRRGTDV KAL
Sbjct: 237 LKAVEAGVDGIIVSNHGGRQLDYSPATITVLEEVVQVVRGRIPVLLDGGVRRGTDVFKAL 296

Query: 312 ALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLV 367
           ALGA AVLIGRPI++GLA  GE+GV +++ +LK+EF++ M L GC  + DI R+ V
Sbjct: 297 ALGAQAVLIGRPIIYGLAAKGEDGVKKVIDMLKNEFEITMALSGCPTIDDITRNHV 352

gb|AAH74200.1| MGC82107 protein [Xenopus laevis]
(356 aa)

Score: 360 bits (923), Expect: 5.13989e-98
Length: 352, Idn/Pos/Gap = 173/247/6 (49%/70%/1%)

Query:  16 LAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVM  75
           LA++  +AK  LP   + YYA+GAD+  T  DN +AFRR+R RPR+L DVS +D    V+
Sbjct:   6 LADFEAYAKENLPKATWEYYAAGADECCTRDDNLQAFRRIRLRPRMLRDVSVMDTKTTVL  65

Query:  76 GIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPK 135
           G ++S P+ +APTA   +A P+GE++TARA   +  +   S++AT S+E+++   P   +
Sbjct:  66 GEEISCPIGIAPTAFHCLAWPDGEMSTARAAEALNLLYVASTYATCSVEEISQAAPEGLR 125

Query: 136 FFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANFA 195
           +FQLYVY+DR ++E+L+RR E  GF+A+ LTVD P  G+R  DIRN F+LPPHL + NF 
Sbjct: 126 WFQLYVYRDRKLSEQLIRRVEALGFKALVLTVDVPYTGKRRTDIRNNFRLPPHLKVKNFE 185

Query: 196 DMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQRAL 255
            +      +G +G       V +L D S++W DI WL+S+T+LPI++KG++T EDA+ A+
Sbjct: 186 GV-----FEGHSGPDNYGVPVNTL-DPSVSWKDICWLRSVTKLPIVIKGILTKEDAELAV 239

Query: 256 QYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALALGA 315
            YG  GI +SNHG RQLDG  ATID L E+A+ V+GRI V++D G+R G+DV+KA+ALGA
Sbjct: 240 VYGVQGIIVSNHGGRQLDGELATIDALSEIAEVVQGRIEVYLDGGIRTGSDVLKAIALGA 299

Query: 316 DAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLV 367
             V +GRPIVWGL   GEEGV  +L +L DEF+L+M L GC+ VS++ R+L+
Sbjct: 300 KCVFLGRPIVWGLTYKGEEGVKGILQILTDEFRLSMALSGCRNVSEVNRNLI 351

dbj|BAB02979.1| glycolate oxidase [Arabidopsis thaliana]
(365 aa)

Score: 359 bits (921), Expect: 9.06487e-98
Length: 358, Idn/Pos/Gap = 185/255/8 (51%/71%/2%)

Query:  12 QPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDIT  71
           Q +N+ E+   AK  LP M Y +Y  GA+D+ TL +N +AFRR+ FRPRVL+DVS++D++
Sbjct:   3 QIVNVDEFQELAKQALPKMYYDFYNGGAEDQHTLNENVQAFRRIMFRPRVLVDVSKIDMS  62

Query:  72 KQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGL--SSWATTSLEDVAAH 129
            +++G  +S P+M+APT   ++AHPEGE ATA+A A   T+M L  S  ++ + E++A+ 
Sbjct:  63 TKILGYPISAPIMIAPTGNHKLAHPEGETATAKAAAACNTIMVLRVSYMSSCTFEEIASS 122

Query: 130 VPGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHL 189
              + +F Q+YVYK R IT ++V+RAE+AGF+AI LTVD P+LGRREADI+N+   P   
Sbjct: 123 CNAV-RFLQIYVYKRRDITAQVVKRAEKAGFKAIVLTVDVPRLGRREADIKNKMISP--- 178

Query: 190 SLANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAE 249
            L NF  +  F+     +  SG+ ++ +   DAS +W DI WL+SIT LPIL+KG++T E
Sbjct: 179 QLKNFEGL--FSTEVRPSKGSGVQAFASRAFDASFSWKDIEWLRSITELPILVKGILTRE 236

Query: 250 DAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVK 309
           DA +A++ G DGI +SNHG RQLD   ATI  LEEV Q VRGRIPV +D GVRRGTDV K
Sbjct: 237 DALKAVEAGVDGIIVSNHGGRQLDYSPATITVLEEVVQVVRGRIPVLLDGGVRRGTDVFK 296

Query: 310 ALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLV 367
           ALALGA AVLIGRPI++GLA  GE+GV +++ +LK+EF++ M L GC  + DI R+ V
Sbjct: 297 ALALGAQAVLIGRPIIYGLAAKGEDGVKKVIDMLKNEFEITMALSGCPTIDDITRNHV 354

gb|AAH55638.1| LOC402827 protein [Danio rerio]
(372 aa)

Score: 358 bits (920), Expect: 1.02734e-97
Length: 314, Idn/Pos/Gap = 176/233/1 (56%/74%/0%)

Query:  57 FRPRVLIDVSRVDITKQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLS 116
           F PRVL DVS VD++  V+G  +S P+ V+ TAMQRMAHP+GE ATARA    GT M LS
Sbjct:  52 FYPRVLRDVSSVDLSTTVLGQRVSLPICVSATAMQRMAHPDGETATARACLSSGTGMMLS 111

Query: 117 SWATTSLEDVAAHVPGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRRE 176
           SW+T+S+E+V    PG  ++ QLY+YKDR +T+ LVRRAE AG++ I +TVDTP LGRR 
Sbjct: 112 SWSTSSIEEVCEAAPGAVRWLQLYIYKDRGLTQSLVRRAEDAGYKGIFVTVDTPYLGRRR 171

Query: 177 ADIRNQFQLPPHLSLANFADMK-DFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSI 235
            D+RN+F+LP HL +ANF      F++ +G    SGLA YV   IDA++ W DI WLK++
Sbjct: 172 DDVRNRFKLPSHLRMANFESPDLAFSKKEGYGEDSGLAVYVTQAIDATVRWQDIGWLKTL 231

Query: 236 TRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPV 295
           T+LP+++KGV+TAEDA+ AL+YG DGI +SNHGARQLDGV ATID L EV  +V G++ V
Sbjct: 232 TKLPVVVKGVLTAEDAKEALEYGVDGILVSNHGARQLDGVPATIDALPEVVAAVAGQVEV 291

Query: 296 FIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCG 355
           F+D GVR G+DV+KALALGA AV IGRP++W LA  GE+GV  +L +L++E  LA+ L G
Sbjct: 292 FMDGGVRMGSDVLKALALGAKAVFIGRPVLWALACQGEKGVSDVLEILREELHLALALAG 351

Query: 356 CQKVSDIRRDLVVR 369
           C+ + ++ R L+ R
Sbjct: 352 CRSLKEVNRSLLRR 365

gb|AAM67194.1| glycolate oxidase, putative [Arabidopsis thaliana]
(363 aa)

Score: 358 bits (919), Expect: 1.42245e-97
Length: 356, Idn/Pos/Gap = 182/254/6 (51%/71%/1%)

Query:  12 QPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDIT  71
           Q +N+ E+   AK  LP M Y +Y  GA+D+ TL +N +AFRR+ FRPRVL+DVS++D++
Sbjct:   3 QIVNVDEFQELAKQALPKMYYDFYNGGAEDQHTLNENVQAFRRIMFRPRVLVDVSKIDMS  62

Query:  72 KQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVP 131
            +++G  +S P+M+APT   ++AH EGE ATA+A A   T+M +S  ++ + E++A+   
Sbjct:  63 TKILGYPISAPIMIAPTGNHKLAHLEGETATAKAAAACNTIMIVSYMSSCTFEEIASSCN 122

Query: 132 GLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSL 191
            + +F Q+YVYK R IT ++V+RAE+AGF+AI LTVD P+LGRREADI+N+   P    L
Sbjct: 123 AV-RFLQIYVYKRRDITAQVVKRAEKAGFKAIVLTVDVPRLGRREADIKNKMISP---QL 178

Query: 192 ANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDA 251
            NF  +  F+     +  SG+ ++ +   DAS +W DI WL+SIT LPIL+KG++T EDA
Sbjct: 179 KNFEGL--FSTEVRPSKGSGVQAFASRAFDASFSWKDIEWLRSITELPILVKGILTREDA 236

Query: 252 QRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKAL 311
            +A++ G DGI +SNHG RQLD   ATI  LEEV Q VRGRIPV +D GVRRGTDV KAL
Sbjct: 237 LKAVEAGVDGIIVSNHGGRQLDYSPATITVLEEVVQVVRGRIPVLLDGGVRRGTDVFKAL 296

Query: 312 ALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLV 367
           ALGA AVLIGRP+++GLA  GE+GV +++ +LK+EF++ M L GC  + DI R+ V
Sbjct: 297 ALGAQAVLIGRPMIYGLAAKGEDGVKKVIDMLKNEFEITMALSGCPTIDDITRNHV 352

gb|AAH73662.1| LOC398510 protein [Xenopus laevis]
(356 aa)

Score: 357 bits (915), Expect: 4.53654e-97
Length: 354, Idn/Pos/Gap = 172/244/10 (48%/68%/2%)

Query:  16 LAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVM  75
           LA++  +AK  LP   + YYA+GAD+  T  DN + FRR+R RPR+L DVS +D    V+
Sbjct:   6 LADFEAYAKENLPKATWEYYAAGADECYTRDDNLQGFRRIRLRPRMLRDVSVMDTKTTVL  65

Query:  76 GIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPK 135
           G D+S P+ +APTA   +A  +GE++TARA   +  +   S++AT S+E+++   P   +
Sbjct:  66 GEDISCPIAIAPTAFHCLAWSDGEMSTARAAEALKLLYVASTYATCSVEEISQAAPEGLR 125

Query: 136 FFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANFA 195
           +FQLYVY++R ++ERL+RR E  GF+A+ LTVD P  G+R  DIRN FQLPPHL + NF 
Sbjct: 126 WFQLYVYRERKLSERLIRRVEALGFKALVLTVDVPYTGKRRTDIRNNFQLPPHLKVKNFE 185

Query: 196 DMKDFAQVKGGAGASGLASYVASL--IDASLNWNDIAWLKSITRLPILLKGVVTAEDAQR 253
            + +        G SG  +Y   L  +D S++W DI WL+S+T LPI++KG++T EDA+ 
Sbjct: 186 GVFE--------GHSGPDNYGVPLNTLDPSVSWKDICWLRSVTNLPIVIKGILTKEDAEL 237

Query: 254 ALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALAL 313
           A+ YG  GI +SNHG RQLDG  ATID L E+ + V+GRI V++D G+R G+DV+KA+AL
Sbjct: 238 AVVYGVQGIIVSNHGGRQLDGELATIDALSEIVEVVQGRIEVYLDGGIRTGSDVLKAIAL 297

Query: 314 GADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLV 367
           GA  V +GRPIVWGL   GEEGV  +L +L DEF+L+M L GC+ +S++ R+L+
Sbjct: 298 GAKCVFLGRPIVWGLTYKGEEGVKGILQILTDEFRLSMALSGCRNISEVNRNLI 351

ref|NP_724983.2| CG30019-PB, isoform B [Drosophila melanogaster]
gb|AAF58735.3| CG30019-PB, isoform B [Drosophila melanogaster]
(400 aa)

Score: 355 bits (911), Expect: 1.29809e-96
Length: 349, Idn/Pos/Gap = 181/244/0 (51%/69%/0%)

Query:  23 AKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGIDLSFP  82
           A  +L      YY SGA ++ TL  N EAFRRLR RPR L DVSR+DI+ ++ G  + +P
Sbjct:  47 AVGQLEKNALDYYRSGAGEQFTLGLNREAFRRLRLRPRCLRDVSRLDISTKIFGEQMQWP 106

Query:  83 LMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFFQLYVY 142
           L +APTAMQ+MAHP+GE+  ARA  + G++  LS+ +TTSLED+AA  P   K+FQLY+Y
Sbjct: 107 LGIAPTAMQKMAHPDGEVGNARAAGKAGSIFILSTLSTTSLEDLAAGAPDTIKWFQLYIY 166

Query: 143 KDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANFADMKDFAQ 202
           KDR ITE+LVRRAE+A F+A+ LT+D P  G R AD+RN F LP HLSLANF  +K    
Sbjct: 167 KDRTITEKLVRRAEKANFKALVLTIDAPIFGHRRADVRNNFSLPSHLSLANFQGVKATGV 226

Query: 203 VKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQRALQYGADGI 262
                GASG+  YV+S  D ++ W DIAWLK IT LPI++KGV+TAEDA  A ++G  G+
Sbjct: 227 GNAAMGASGINEYVSSQFDPTITWKDIAWLKGITHLPIVVKGVLTAEDAVLAQEFGCAGL 286

Query: 263 WISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALALGADAVLIGR 322
            +SNHGARQ+D V A+I+ L E+ ++V   + V +D G+ +G D+ KALALGA  V +GR
Sbjct: 287 IVSNHGARQIDTVPASIEALPEIVKAVGDNLVVMLDGGIMQGNDIFKALALGAKTVFVGR 346

Query: 323 PIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLVVRDA 371
           P VWGLA +G++GV  +LS+L+ +F+  M L GCQ + DI   +VV ++
Sbjct: 347 PAVWGLAYNGQKGVEEMLSVLRKDFETTMALIGCQNLGDITSAMVVHES 395

gb|AAH91092.1| Unknown (protein for MGC:108441) [Xenopus tropicalis]
(356 aa)

Score: 355 bits (910), Expect: 1.62608e-96
Length: 354, Idn/Pos/Gap = 172/245/10 (48%/69%/2%)

Query:  16 LAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVM  75
           LA++  +AK  LP   + YYA+GAD+  T  DN +AFRR+R RPR+L DVS +D    V+
Sbjct:   6 LADFEAYAKEHLPKATWEYYAAGADECCTRDDNLQAFRRIRLRPRMLRDVSVMDTKTTVL  65

Query:  76 GIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPK 135
           G ++S P+ +APTA   +A P+GE++TARA   +  +   S++AT S+E+++   P   +
Sbjct:  66 GEEISCPIGIAPTAFHCLAWPDGEMSTARAAEALKLLYVASTYATCSVEEISEAAPEGLR 125

Query: 136 FFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANFA 195
           +FQLYVY+DR ++E+L+RR E  GF+A+ LTVD P  G+R  DIRN F+LPPHL + NF 
Sbjct: 126 WFQLYVYRDRKLSEQLIRRVEALGFKALVLTVDVPYTGKRRTDIRNNFRLPPHLKVKNFE 185

Query: 196 DMKDFAQVKGGAGASGLASYVASL--IDASLNWNDIAWLKSITRLPILLKGVVTAEDAQR 253
            + +        G  G  +Y   L  +D S++W DI WL+S+T LPI++KG++T EDA+ 
Sbjct: 186 GVFE--------GHGGPDNYGVPLNTLDPSVSWKDICWLRSVTSLPIVIKGILTKEDAEL 237

Query: 254 ALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALAL 313
           A+ YG  GI +SNHG RQLDG  ATID L E+ + V+GRI V++D G+R G+DV+KA+AL
Sbjct: 238 AVVYGVQGIIVSNHGGRQLDGELATIDALAEIVEVVQGRIEVYLDGGIRTGSDVLKAIAL 297

Query: 314 GADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLV 367
           GA  V +GRPIVWGL   GEEGV  +L +L DEF+L+M L GC+ VS++ R+L+
Sbjct: 298 GAKCVFLGRPIVWGLTYKGEEGVKGILQILTDEFRLSMALSGCRNVSEVNRNLI 351

ref|ZP_00326069.1| COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Trichodesmium erythraeum IMS101]
(359 aa)

Score: 354 bits (908), Expect: 2.53044e-96
Length: 358, Idn/Pos/Gap = 183/248/4 (51%/69%/1%)

Query:  12 QPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDIT  71
           +P+N+ EY   A   L  M   YYASGA DE TLRDN  A+ + + RPR+L+DVS+ +++
Sbjct:   3 KPINIFEYESLAPKYLSQMALDYYASGAWDEVTLRDNRTAYEKYKLRPRMLVDVSQRNLS  62

Query:  72 KQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVA--AH 129
            +++G  +  P+++AP A Q +AHPEGELATAR  A  G  M LS+ +T SLEDVA   +
Sbjct:  63 TKILGQLMKMPILIAPMAFQCLAHPEGELATARVAADHGITMVLSTMSTKSLEDVALATN 122

Query: 130 VPGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHL 189
           VP    +FQLYV++DR +T  LV RA+ AG++A+ LTVD P LG RE D RNQF LP  L
Sbjct: 123 VPQ-SLWFQLYVHRDRFLTRTLVERAKAAGYQALCLTVDAPVLGVRERDRRNQFTLPSGL 181

Query: 190 SLANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAE 249
            LAN   M +  ++      SGL +YVA+  D +L W D+ WL+S+T LP+++KG++  +
Sbjct: 182 ELANLTSMANL-EIPETEEESGLFAYVANQFDPALTWQDLEWLQSLTSLPVIVKGILRGD 240

Query: 250 DAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVK 309
           DA RA+++GA GI +SNHG RQLDG  ATID L EV  +V  ++ V +D G+RRGTD++K
Sbjct: 241 DAVRAVEHGAKGIIVSNHGGRQLDGAIATIDALPEVVAAVGNKVDVLMDGGIRRGTDILK 300

Query: 310 ALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLV 367
           ALALGA AVLIGRP++W LAV+GE GV+ LL LL++E  +AM L GC KV +I   LV
Sbjct: 301 ALALGAKAVLIGRPVLWALAVNGETGVHHLLELLRNELDVAMALSGCAKVENINPSLV 358

gb|EAL25953.1| GA15579-PA [Drosophila pseudoobscura]
(366 aa)

Score: 353 bits (907), Expect: 3.41702e-96
Length: 350, Idn/Pos/Gap = 180/244/0 (51%/69%/0%)

Query:  23 AKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGIDLSFP  82
           A  +L      YY SGA ++ TL  N EAFRRLR RPR L DVSR+DI+  + G  + +P
Sbjct:  13 AAGKLEKNALDYYRSGAGEQFTLGLNREAFRRLRLRPRCLRDVSRLDISCPIFGEQMKWP  72

Query:  83 LMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFFQLYVY 142
           L +APTAMQ+MAH +GE+  ARA  + G++  LS+ +TTSLED+AA  P   K+FQLY+Y
Sbjct:  73 LGIAPTAMQKMAHSDGEVGNARAAGKAGSIFILSTLSTTSLEDLAAGAPDTCKWFQLYIY 132

Query: 143 KDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANFADMKDFAQ 202
           KDR ITE+LVRRAE+A F+A+ LT+D P  G R AD+RN F LP HL+LANF  +K    
Sbjct: 133 KDRTITEKLVRRAEKANFKALVLTIDAPIFGHRRADVRNNFSLPSHLTLANFQGVKATGV 192

Query: 203 VKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQRALQYGADGI 262
                GASG+  YV+S  D ++ W DI WLKSIT LPI++KG++TAEDA  A ++G  GI
Sbjct: 193 ATTSMGASGINEYVSSQFDPTITWQDIKWLKSITHLPIVVKGILTAEDAVLAKEFGCAGI 252

Query: 263 WISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALALGADAVLIGR 322
            +SNHGARQ+D V A+I+ L EVA++V   + V +D G+ +G D+ KALALGA  V +GR
Sbjct: 253 IVSNHGARQIDTVPASIEALPEVAKAVGNDLLVMLDGGIMQGNDIFKALALGAKTVFVGR 312

Query: 323 PIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLVVRDAF 372
           P VWGLA +G++GV  +L +L+ +F++ M L GCQ + DI+  +VV ++ 
Sbjct: 313 PAVWGLAYNGQKGVEEMLGVLRKDFEITMALIGCQTLKDIKSSMVVHESL 362

ref|NP_788326.1| CG30019-PC, isoform C [Drosophila melanogaster]
gb|AAO41411.1| CG30019-PC, isoform C [Drosophila melanogaster]
(366 aa)

Score: 353 bits (906), Expect: 5.05776e-96
Length: 349, Idn/Pos/Gap = 181/244/0 (51%/69%/0%)

Query:  23 AKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGIDLSFP  82
           A  +L      YY SGA ++ TL  N EAFRRLR RPR L DVSR+DI+ ++ G  + +P
Sbjct:  13 AVGQLEKNALDYYRSGAGEQFTLGLNREAFRRLRLRPRCLRDVSRLDISTKIFGEQMQWP  72

Query:  83 LMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFFQLYVY 142
           L +APTAMQ+MAHP+GE+  ARA  + G++  LS+ +TTSLED+AA  P   K+FQLY+Y
Sbjct:  73 LGIAPTAMQKMAHPDGEVGNARAAGKAGSIFILSTLSTTSLEDLAAGAPDTIKWFQLYIY 132

Query: 143 KDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANFADMKDFAQ 202
           KDR ITE+LVRRAE+A F+A+ LT+D P  G R AD+RN F LP HLSLANF  +K    
Sbjct: 133 KDRTITEKLVRRAEKANFKALVLTIDAPIFGHRRADVRNNFSLPSHLSLANFQGVKATGV 192

Query: 203 VKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQRALQYGADGI 262
                GASG+  YV+S  D ++ W DIAWLK IT LPI++KGV+TAEDA  A ++G  G+
Sbjct: 193 GNAAMGASGINEYVSSQFDPTITWKDIAWLKGITHLPIVVKGVLTAEDAVLAQEFGCAGL 252

Query: 263 WISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALALGADAVLIGR 322
            +SNHGARQ+D V A+I+ L E+ ++V   + V +D G+ +G D+ KALALGA  V +GR
Sbjct: 253 IVSNHGARQIDTVPASIEALPEIVKAVGDNLVVMLDGGIMQGNDIFKALALGAKTVFVGR 312

Query: 323 PIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLVVRDA 371
           P VWGLA +G++GV  +LS+L+ +F+  M L GCQ + DI   +VV ++
Sbjct: 313 PAVWGLAYNGQKGVEEMLSVLRKDFETTMALIGCQNLGDITSAMVVHES 361

ref|XP_479166.1| putative (S)-2-hydroxy-acid oxidase [Oryza sativa (japonica cultivar-group)]
dbj|BAC79990.1| putative (S)-2-hydroxy-acid oxidase [Oryza sativa (japonica cultivar-group)]
(366 aa)

Score: 352 bits (903), Expect: 1.054e-95
Length: 359, Idn/Pos/Gap = 179/241/5 (49%/67%/1%)

Query:  13 PLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITK  72
           P+N+ EY   AK  LP M Y Y   GA+DE TLR+N  A+ R+  RPRVL+DVS++D++ 
Sbjct:   6 PVNVREYQELAKKALPKMAYDYINGGAEDEHTLRENIAAYTRIILRPRVLVDVSKIDMST  65

Query:  73 QVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPG 132
            ++G  +  P++VAPT   ++AHPEGE ATARA A    +M LS  ++  +EDVA+    
Sbjct:  66 TLLGYTMRSPIIVAPTGGHKLAHPEGEKATARAAASCNAIMVLSFSSSCKIEDVASSCNA 125

Query: 133 LPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLA 192
           + +F+QLYVYK+R ++  LVRRAE  GF+A+ LTVDTP LGRREADIRN+   P   +L 
Sbjct: 126 I-RFYQLYVYKNRNVSATLVRRAESCGFKALLLTVDTPMLGRREADIRNKMVFPRSGNLE 184

Query: 193 NFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQ 252
                 D     G    S L  +  + +D SL+W DI WLKSIT +PI LKG+VTAEDA+
Sbjct: 185 GLMTTDDHDTTNG----SQLERFARATLDPSLSWKDIEWLKSITSMPIFLKGIVTAEDAR 240

Query: 253 RALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALA 312
           RA++ G  G+ +SNHGARQLD   ATI  LEEV ++V G +PV +D G+RRGTDV KALA
Sbjct: 241 RAVEAGVAGVIVSNHGARQLDYAPATIAALEEVVRAVAGAVPVLVDGGIRRGTDVFKALA 300

Query: 313 LGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLVVRDA 371
           LGA AV++GRP+ +GLA  GE G   ++ +L  E ++AM LCGC+ V +I R  V+ + 
Sbjct: 301 LGARAVMVGRPVFFGLAARGEAGARHVIEMLNGELEVAMALCGCRSVGEITRSHVMTEG 359

gb|EAA05477.2| ENSANGP00000018221 [Anopheles gambiae str. PEST]
ref|XP_309809.2| ENSANGP00000018221 [Anopheles gambiae str. PEST]
(363 aa)

Score: 346 bits (887), Expect: 8.7775e-94
Length: 357, Idn/Pos/Gap = 174/240/3 (48%/67%/0%)

Query:  14 LNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQ  73
           +++ +Y   A   +P     YY SGA DE +L  N   F RLR RPR+L   S  D++  
Sbjct:   4 VSVRDYEKRAHEIIPRNALDYYRSGAGDELSLHLNRTGFDRLRIRPRMLQGGSTRDLSCT  63

Query:  74 VMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGL 133
           V G   S P+ ++PTAMQRMAHP+GE+A A+A A    +  LS+ +T+S+E VA   P  
Sbjct:  64 VFGQRFSMPIAISPTAMQRMAHPDGEVANAKAAATRQVLFTLSTISTSSIEQVAEATPNA 123

Query: 134 PKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLAN 193
           PK+FQLY+Y+DR +TE LVRRAERAGFRAI LTVD P  G R AD+RN+F LPPHLS+AN
Sbjct: 124 PKWFQLYIYRDRQLTEELVRRAERAGFRAIVLTVDAPLFGLRRADMRNKFSLPPHLSMAN 183

Query: 194 FADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQR 253
           F       + +GG   SG+  Y+A  +D +L+W+D+ WL   T+LP+++KG++T EDA  
Sbjct: 184 FVGKAASIRSQGG---SGINEYIAEQLDPTLSWDDVKWLLGFTKLPVIVKGILTREDAII 240

Query: 254 ALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALAL 313
           A   G  GI++SNHGARQLD V A+I+ L E+  +V  R+ +F+D G+ +GTDV KALAL
Sbjct: 241 AADLGVQGIFVSNHGARQLDSVPASIEALPEIVAAVGRRVEIFLDGGITQGTDVFKALAL 300

Query: 314 GADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLVVRD 370
           GA  V  GRP +WGLAV+G+ GV  +L +L++E  L M L GC+ ++DI ++ VV +
Sbjct: 301 GARMVFFGRPALWGLAVNGQAGVEHVLDILRNELDLTMALAGCKTLADITKEYVVHE 357

ref|XP_542897.1| PREDICTED: similar to glycolate oxidase; short-chain alpha-hydroxy acid oxidase [Canis familiaris]
(438 aa)

Score: 344 bits (882), Expect: 3.09415e-93
Length: 433, Idn/Pos/Gap = 187/265/71 (43%/61%/16%)

Query:  11 TQPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFR------------  58
           T+ + +++Y   AK+ L   +Y YY SGA+D++TL DN  AF R + R            
Sbjct:   3 TRLVCISDYEQNAKSVLQKSIYDYYRSGANDQETLADNIAAFSRSKKRAVRVSPKERTSS  62

Query:  59 ----------------------------PRVLIDVSRVDITKQVMGIDLSFPLMVAPTAM  90
                                       PR+L +V+ +D++  V+G  +S P+ V  TAM
Sbjct:  63 SKACGVTENNDDYDVQRNCREIAQWKLYPRMLRNVAEIDLSTSVLGQRVSMPICVGATAM 122

Query:  91 QRMAHPEGELATARAVA----------------------------RIGTVMGLSSWATTS 122
           Q MAH +GELAT R V+                             +GT M LSSW+T+S
Sbjct: 123 QCMAHVDGELATVRDVSTLEPQPEGFGVGKVPDSSLPLPFSSACRSLGTGMMLSSWSTSS 182

Query: 123 LEDVAAHVPGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQ 182
           +E+VA   P   ++ QLY+YKDR +T++LV+RAER G++AI LTVDTP LG R  D+RN+
Sbjct: 183 IEEVAEASPDALRWLQLYIYKDREVTKQLVQRAERKGYKAIFLTVDTPYLGNRFDDVRNR 242

Query: 183 FQLPPHLSLANFADMKD--FAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPI 240
           F+LPP L + NF +  D  F+  +     SGLA+YVA  ID S++W DI WL+ +T LPI
Sbjct: 243 FKLPPQLRMKNF-ETNDLAFSPKENFGDNSGLATYVAKSIDPSISWEDIKWLRGLTSLPI 301

Query: 241 LLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSG 300
           + KG++  +DA+ A+++G +GI +SNHGARQLDGV ATID L E+ ++V G++ +F+D G
Sbjct: 302 VAKGILRGDDAKEAVKHGLNGILVSNHGARQLDGVPATIDALPEIVEAVEGKVEIFLDGG 361

Query: 301 VRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVS 360
           VR+GTDV+KALALGA AV +GRP++WGLA  GE+GV  +L +LK+EF+LAM L GCQ V 
Sbjct: 362 VRKGTDVLKALALGAKAVFVGRPVIWGLASQGEKGVQDVLEILKEEFRLAMALSGCQNVK 421

Query: 361 DIRRDLVVRDAFA 373
            I + LV ++  A
Sbjct: 422 VIDKTLVRKNPLA 434

ref|NP_956777.1| hypothetical protein LOC393455 [Danio rerio]
gb|AAH55205.1| Hypothetical protein MGC63690 [Danio rerio]
(357 aa)

Score: 340 bits (872), Expect: 4.77635e-92
Length: 352, Idn/Pos/Gap = 169/245/5 (48%/69%/1%)

Query:  16 LAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVM  75
           L ++  +AK  L    + YY +GAD+  T  DN +A++R+R RPR+L DVS  D    V+
Sbjct:   6 LDDFEEYAKQHLSKSTWDYYEAGADECCTRDDNLQAYKRIRLRPRILRDVSINDTRTSVL  65

Query:  76 GIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPK 135
           G ++SFP+ +APTA   +A  EGELATARA   + T    S++AT S+E++AA  P   +
Sbjct:  66 GREISFPVGIAPTAFHCLAWHEGELATARATEALNTCYIASTYATCSVEEIAAAAPNGYR 125

Query: 136 FFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANFA 195
           +FQLY+Y+DR ++E++V R E  G++A+ LTVD P  G+R  DIRNQF+LPPHL + NF 
Sbjct: 126 WFQLYLYRDRKLSEQIVHRVEALGYKALVLTVDVPYTGKRRNDIRNQFKLPPHLKVKNFE 185

Query: 196 DMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQRAL 255
            M  F +        G+    A+ +D S++W D+ WL+S+TRLPI++KG++T EDA+ A+
Sbjct: 186 GM--FQEQTEAQEEYGIP---ANTLDPSISWKDVCWLQSLTRLPIIIKGILTKEDAELAV 240

Query: 256 QYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALALGA 315
           ++G  GI +SNHG RQLDG  ATIDCL E+  +V+GR+ V++D G+R G DV+KA+ALGA
Sbjct: 241 EHGVQGIIVSNHGGRQLDGGPATIDCLPEIVDTVQGRVEVYMDGGIRTGNDVLKAIALGA 300

Query: 316 DAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLV 367
             V IGRP +WGLA  GE+GV  +L++L DEF+L+M L GC+ V++I R+L+
Sbjct: 301 RCVFIGRPAIWGLAYKGEDGVKEILNILHDEFRLSMVLAGCRNVAEINRNLI 352

ref|ZP_00106740.1| COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Nostoc punctiforme PCC 73102]
(373 aa)

Score: 333 bits (855), Expect: 3.91184e-90
Length: 364, Idn/Pos/Gap = 179/247/4 (49%/67%/1%)

Query:  12 QPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDIT  71
           QP+NL EY   AK  L  M   YY+SGA DE TLRDN  AF R++ RPR+L+DVS  ++T
Sbjct:  11 QPINLFEYEKLAKEHLSQMTLDYYSSGAWDEITLRDNRAAFERVKLRPRILVDVSDRNLT  70

Query:  72 KQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVP 131
             ++G  L  PL++AP A Q +AHP+GE+ATA A A  G  M LS+ AT S+E+VA    
Sbjct:  71 TSILGQPLQLPLLIAPMAFQCLAHPDGEVATALAAASAGVGMVLSTMATKSIEEVATACD 130

Query: 132 GLP---KFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPH 188
             P   ++FQLY++KD+ +T  LV +A +AG++A+ LTVD P LG+RE D RN+F LP  
Sbjct: 131 KFPESLRWFQLYIHKDKGLTRALVEKAYKAGYKALCLTVDAPVLGQRERDRRNEFALPTD 190

Query: 189 LSLANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTA 248
           L LAN A +     +    G SGL +Y A  ++ ++ W+D+ WL+S++ LP+++KGV+  
Sbjct: 191 LHLANLATISGL-DISHEKGESGLFTYFAQQLNPAVTWDDLEWLQSLSPLPLVIKGVLRG 249

Query: 249 EDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVV 308
           +DA RA++YGA  I +SNHG RQLDG  A++D L E+  +V G+I V +D G+RRGTD++
Sbjct: 250 DDAVRAVEYGAKAIVVSNHGGRQLDGAIASLDALVEIVAAVDGKIEVLLDGGIRRGTDIL 309

Query: 309 KALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLVV 368
           KALALGA AVLIGRPI+WGLAV G+ GV  ++SLL+ E  + M L GC K+ DI   L+ 
Sbjct: 310 KALALGAKAVLIGRPILWGLAVAGQVGVSHVISLLQGELNVGMALSGCAKLQDINLSLLT 369

Query: 369 RDAF 372
              F
Sbjct: 370 LPRF 373

ref|ZP_00160276.2| COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Anabaena variabilis ATCC 29413]
(366 aa)

Score: 331 bits (849), Expect: 2.05819e-89
Length: 355, Idn/Pos/Gap = 176/245/4 (49%/69%/1%)

Query:  11 TQPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDI  70
           + P+NL EY   AK  L  M + YY SGA DE TL++N  AF R++ RPR+L+DVS++++
Sbjct:   5 SSPINLFEYEQLAKTHLSQMAFDYYISGAGDEITLQENRTAFERIKLRPRMLVDVSQINL  64

Query:  71 TKQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVA--- 127
           T  V+G  L  PL++AP A Q +AH EGELATA A A  G  M LS+ +T SLE+VA   
Sbjct:  65 TTSVLGQPLQLPLLIAPMAFQCLAHAEGELATAMAAASAGVGMVLSTLSTKSLEEVAEVG 124

Query: 128 AHVPGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPP 187
           +      ++FQLY++KD+ +T  LV RA  AG++A+ LTVD P LG+RE D RN+F LPP
Sbjct: 125 SKFSDSLQWFQLYIHKDQGLTRALVERAYTAGYKALCLTVDAPVLGQRERDRRNEFALPP 184

Query: 188 HLSLANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVT 247
            L LAN A +     +    G SGL +Y A  ++++L W D+ WL+S++ LP++LKG++ 
Sbjct: 185 GLDLANLATISGL-DIPYVPGESGLLTYFAQQLNSALTWEDLEWLQSLSPLPLVLKGILR 243

Query: 248 AEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDV 307
            +DA RA++YGA  I +SNHG RQLDG  A++D L E+  +V G+  V +D G+RRGTD+
Sbjct: 244 GDDAARAVEYGAKAIVVSNHGGRQLDGAIASLDALPEIVAAVNGKAEVLLDGGIRRGTDI 303

Query: 308 VKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDI 362
           +KALA+GA AVLIGRPI+WGLAV G+ GV  ++SLL+ E  +AM L GC ++ DI
Sbjct: 304 IKALAIGAQAVLIGRPILWGLAVGGQAGVSHVISLLQKELNVAMALMGCSQLQDI 358

pir||T31874 hypothetical protein F41E6.5 - Caenorhabditis elegans
(371 aa)

Score: 330 bits (847), Expect: 3.36729e-89
Length: 355, Idn/Pos/Gap = 170/228/3 (47%/64%/0%)

Query:  14 LNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQ  73
           L L +Y  F++  L  +   YY SGA+ E++LR N  AF  L  RPR L  V  +D +  
Sbjct:   7 LTLDDYRKFSEKNLVKLARDYYESGAEQEESLRRNISAFNNLLIRPRCLRSVENIDTSID  66

Query:  74 VM-GIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVA--AHV 130
            + G    FP+ +APTA Q+MA  +GEL+T R  A   ++M  SSW+TTS+ED+   A +
Sbjct:  67 WLNGKKSVFPVGIAPTAFQKMATLDGELSTVRGAAASNSIMICSSWSTTSVEDIGKEAKI 126

Query: 131 PGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLS 190
            G   +FQLYVYKDRAITE L+ RAE AG  A+ LTVDTP LGRR  D  N+F LP HL 
Sbjct: 127 VGATIWFQLYVYKDRAITESLIHRAEAAGVEALVLTVDTPVLGRRLKDTYNKFSLPKHLK 186

Query: 191 LANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAED 250
            ANF         KG  G SG   YV+S ID SL+WN + W+++ T LP+++KGV+  +D
Sbjct: 187 FANFESNTQAEMPKGHVGESGFMQYVSSQIDPSLDWNTLKWIRTKTNLPVIVKGVMRGDD 246

Query: 251 AQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKA 310
           A  AL+ G DGI +SNHG RQ+D   ATI+ L EV ++V  RIPV++D GVR G D++KA
Sbjct: 247 ALLALEAGVDGIIVSNHGGRQMDCTVATIESLPEVLRAVDNRIPVWMDGGVRNGRDILKA 306

Query: 311 LALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRD 365
           +ALGA  V +GRP++WGLA  G  GV  +L LL+ EF  A+QL G + + +++ D
Sbjct: 307 VALGARGVFVGRPVLWGLATSGSAGVSAVLGLLQSEFYHALQLSGFRSIKELQND 361

dbj|BAB77694.1| glycolate oxidase [Nostoc sp. PCC 7120]
ref|NP_484214.1| glycolate oxidase [Nostoc sp. PCC 7120]
pir||AB1828 glycolate oxidase [imported] - Nostoc sp. (strain PCC 7120)
(365 aa)

Score: 329 bits (844), Expect: 7.50155e-89
Length: 356, Idn/Pos/Gap = 177/245/6 (49%/68%/1%)

Query:  11 TQPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDI  70
           + P+NL EY   AK  L  M + YY SGA DE TL++N   F R++ RPR+L+DVS++++
Sbjct:   5 SSPINLFEYEQLAKTHLSQMAFDYYISGAGDEITLQENRAVFERIKLRPRMLVDVSQINL  64

Query:  71 TKQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVA--- 127
           T  V+G  L  PL++AP A Q +AH EGELATA A A  GT M LS+ +T SLE+VA   
Sbjct:  65 TTSVLGQPLQLPLLIAPMAFQCLAHTEGELATAMAAASAGTGMVLSTLSTKSLEEVAEVG 124

Query: 128 -AHVPGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLP 186
               P L ++FQLY++KDR +T  LV RA  AG++A+ LTVD P LG+RE D RN+F LP
Sbjct: 125 SKFSPSL-QWFQLYIHKDRGLTRALVERAYAAGYKALCLTVDAPVLGQRERDRRNEFVLP 183

Query: 187 PHLSLANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVV 246
           P L LAN   +     +    G SGL +Y A  ++ +L W+D+ WL+S++ LP++LKG++
Sbjct: 184 PGLHLANLTTISGL-NIPHAPGESGLFTYFAQQLNPALTWDDLEWLQSLSPLPLVLKGIL 242

Query: 247 TAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTD 306
             +DA RA++YGA  I +SNHG RQLDG  A++D L E+  +V G+  V +D G+RRGTD
Sbjct: 243 RGDDAARAVEYGAKAIVVSNHGGRQLDGAIASLDALPEIVAAVNGKAEVLLDGGIRRGTD 302

Query: 307 VVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDI 362
           ++KALA+GA AVLIGRP++WGLAV G+ GV  ++SLL+ E  +AM L GC ++ DI
Sbjct: 303 IIKALAIGAQAVLIGRPVLWGLAVGGQAGVSHVISLLQKELNVAMALIGCSQLQDI 358

emb|CAG08223.1| unnamed protein product [Tetraodon nigroviridis]
(367 aa)

Score: 327 bits (838), Expect: 4.21935e-88
Length: 367, Idn/Pos/Gap = 169/243/15 (46%/66%/4%)

Query:  16 LAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVM  75
           L ++  +AK  L    + YYA+GAD+  T  DN  A++R+R RPR+L DVS  D    + 
Sbjct:   6 LTDFEEYAKEHLSKATWDYYAAGADECCTRDDNLLAYKRIRLRPRILRDVSVSDTRTTIQ  65

Query:  76 GIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPK 135
           G ++SFP+ +APTA   +A  EGE+ATARA   + T    S+++T S+E++ A  P   +
Sbjct:  66 GTEISFPVGIAPTAFHCLAWHEGEMATARATEALNTCYITSTYSTCSVEEIVAAAPNGYR 125

Query: 136 FFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANFA 195
           +FQLY+Y+DR ++E++V R E  G++A+ LTVD P  G+R  DIRNQF+LPPHL + NF 
Sbjct: 126 WFQLYLYRDRKLSEQIVHRVEALGYKALVLTVDVPYTGKRRNDIRNQFKLPPHLKVKNFD 185

Query: 196 DMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQRAL 255
            +  F Q        G+    A+ +D S++W D+ WL+SITRLPI++KG++T EDA+ A+
Sbjct: 186 GV--FQQEAAVTEEYGIP---ANTLDPSISWKDVYWLQSITRLPIIIKGILTKEDAELAV 240

Query: 256 QYGADGIWISNHGARQLDGVTAT----------IDCLEEVAQSVRGRIPVFIDSGVRRGT 305
           ++G  GI +SNHG RQLDG  A+          ID L E+  +V+GRI V++D G+R G+
Sbjct: 241 EHGVQGIIVSNHGGRQLDGGPASLHMPPCFALQIDALSEIVDTVQGRIEVYLDGGIRTGS 300

Query: 306 DVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRD 365
           DV+K+LALGA  V IGRP VWGLA  GEEGV  +L +L DEF+L+M L GC+ V++I R+
Sbjct: 301 DVLKSLALGAKCVFIGRPAVWGLAYKGEEGVREVLQILNDEFRLSMALSGCRNVAEINRN 360

Query: 366 LVVRDAF 372
           L+    F
Sbjct: 361 LIQFSKF 367

emb|CAA63482.1| glycolate oxidase [Lycopersicon esculentum]
pir||T07032 (S)-2-hydroxy-acid oxidase (EC 1.1.3.15) - tomato (fragment)
(290 aa)

Score: 325 bits (834), Expect: 1.05644e-87
Length: 285, Idn/Pos/Gap = 171/222/3 (60%/77%/1%)

Query:  91 QRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFFQLYVYKDRAITER 150
           Q+MAHPEGE ATARA +  GT+M LSSWAT+S+E+VA+  PG+ +FFQLYVYKDR +  +
Sbjct:   1 QKMAHPEGEYATARAASAAGTIMTLSSWATSSVEEVASTGPGI-RFFQLYVYKDRNVVAQ  59

Query: 151 LVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANFADMKDFAQVKGGAGAS 210
           LVRRAE+AGF+AIALTVDTP+LGRREADI+N+F LPP L+L NF  + D  ++   A  S
Sbjct:  60 LVRRAEKAGFKAIALTVDTPRLGRREADIKNRFVLPPFLTLKNFEGL-DLGKMDQ-ANDS 117

Query: 211 GLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQRALQYGADGIWISNHGAR 270
           GLASYVA  ID +L+W D+ WL++IT +PIL+KGV+TA+ A+ A+Q GA GI +SNHGAR
Sbjct: 118 GLASYVAGQIDRTLSWKDVQWLQTITSMPILVKGVITADHARLAVQAGAAGIIVSNHGAR 177

Query: 271 QLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAV 330
           QLD V ATI  LEEV +  +GRIPVF+D GVRRGTDV KALALGA  + IGRP+V+ LA 
Sbjct: 178 QLDYVPATISALEEVVKGAQGRIPVFLDGGVRRGTDVFKALALGASGIFIGRPVVFSLAA 237

Query: 331 DGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLVVRDAFAPY 375
           +GE GV ++L +L+DEF+L M L GC+ + +I R+ +V +   P+
Sbjct: 238 EGEAGVKKVLQMLRDEFELTMALSGCRSLKEITRNHIVTEWDTPH 282

emb|CAE58356.1| Hypothetical protein CBG01477 [Caenorhabditis briggsae]
(372 aa)

Score: 321 bits (823), Expect: 2.04287e-86
Length: 362, Idn/Pos/Gap = 168/228/3 (46%/62%/0%)

Query:   7 VNPATQPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVS  66
           + P    L L +Y  +++  L  +   YY SGA+ E TLR N  AF  L  RPR L  V 
Sbjct:   1 MTPLPSLLTLDDYRKYSERNLIKLARDYYESGAEQETTLRRNVSAFDNLLIRPRCLRSVE  60

Query:  67 RVDITKQVM-GIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLED 125
            +D +   + G   ++PL +APTA Q+MA  +GEL+T R  A   ++M  SSW+TTS+E+
Sbjct:  61 SIDTSVTWLNGKRAAYPLGIAPTAFQKMATKDGELSTVRGAAASKSIMICSSWSTTSIEE 120

Query: 126 VA--AHVPGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQF 183
           +   A + G   +FQLYVYKDR +TE L+ RAE AG  A+ LTVDTP LGRR  D  N+F
Sbjct: 121 IGKEAKIVGAALWFQLYVYKDRNVTESLIHRAEAAGVEALVLTVDTPVLGRRLKDTYNKF 180

Query: 184 QLPPHLSLANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLK 243
            LP HL  ANF         KG  G SG   YV+  ID SL+WN + W+K+ T+LP+++K
Sbjct: 181 SLPHHLKFANFESNTQAEMPKGHTGESGFMQYVSLQIDPSLDWNTLEWIKTKTKLPVIVK 240

Query: 244 GVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRR 303
           GV+  +DA  AL  GADGI +SNHG RQ+D   ATI+ L EV  +V  RIPV++D GVR 
Sbjct: 241 GVMRGDDALLALGAGADGIIVSNHGGRQMDSSIATIEALPEVLAAVDKRIPVWMDGGVRN 300

Query: 304 GTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIR 363
           G D+ KA+ALGA  V +GRP++WGLA  G  GV  +L +L+ EF  +MQL G + + +++
Sbjct: 301 GRDIFKAVALGARGVFVGRPVLWGLATSGSSGVVAVLGILQKEFLHSMQLSGYRSIEELQ 360

Query: 364 RD 365
           +D
Sbjct: 361 KD 362

ref|XP_415025.1| PREDICTED: similar to hydroxyacid oxidase 1; (S)-2-hydroxy-acid oxidase; glycolate oxidase [Gallus gallus]
(358 aa)

Score: 315 bits (807), Expect: 1.46402e-84
Length: 317, Idn/Pos/Gap = 162/216/13 (51%/68%/4%)

Query:  54 RLRFRPRVLIDVSRVDITKQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVM 113
           R +  PRVL DVS +D++  V+G  +S P+ VA TAMQRMAHP+GE ATA+A   +GT M
Sbjct:  46 RWKLYPRVLRDVSVMDLSTSVLGQKISMPVCVAATAMQRMAHPDGETATAKACHAMGTGM 105

Query: 114 GLSSWATTSLEDVAAHVPGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLG 173
            LSSWAT+S+E+VA   PG  ++ QLYVYKDR +T+ LV+RAERAG++ I +TVDTP LG
Sbjct: 106 MLSSWATSSIEEVAEAAPGGLRWLQLYVYKDREVTKSLVKRAERAGYKGIFVTVDTPFLG 165

Query: 174 RREADIRNQFQLPPHLSLANFADMK-DFAQVKGGAGASGLASYVASLIDASLNWNDIAWL 232
           RR  D+RN+FQLPPHL L NF+    DF+    G   SGLA YVA+ IDAS+NW DI WL
Sbjct: 166 RRIDDVRNKFQLPPHLRLKNFSSNNLDFSGRDFGED-SGLAVYVANAIDASVNWEDIKWL 224

Query: 233 KSITRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGR 292
           + +T LPI+ KG++                  +N   +    +   ID L E+ ++V G+
Sbjct: 225 RGLTSLPIVAKGILRENIC----------FSFTNSIGKSCASL-CEIDILPEIVEAVEGK 273

Query: 293 IPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQ 352
           + VF+D G+R+GTD++KALALGA AV IGRP++WGL   GEEG   +L +LK+EF+LAM 
Sbjct: 274 VEVFLDGGIRKGTDILKALALGAKAVFIGRPLIWGLVYQGEEGAKEVLQMLKEEFRLAMA 333

Query: 353 LCGCQKVSDIRRDLVVR 369
           L GC+ V +I R L+ R
Sbjct: 334 LTGCRTVKEIGRTLIRR 350

ref|XP_416535.1| PREDICTED: similar to Hydroxyacid oxidase 2 (HAOX2) ((S)-2-hydroxy-acid oxidase, peroxisomal) (Long chain alpha-hydroxy acid oxidase) (Long-chain L-2-hydroxy acid oxidase) [Gallus gallus]
(653 aa)

Score: 314 bits (805), Expect: 2.3952e-84
Length: 330, Idn/Pos/Gap = 148/229/11 (44%/69%/3%)

Query:  16 LAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVM  75
           L ++  +A+  LP + + ++A+GAD+  T  +N  A++R+RFRPR+L DVS +D   +++
Sbjct: 331 LLDFEAYAEKYLPKIAWDFFAAGADECSTRDENILAYKRIRFRPRMLRDVSMLDTRTKIL 390

Query:  76 GIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPK 135
           G ++SFP+ +APT   ++A P+GE +TARA   +GT    S+++T SLE++AA  PG  +
Sbjct: 391 GTEISFPVGIAPTGFHQLAWPDGEKSTARAAKAMGTCYIASTYSTCSLEEIAAAAPGGFR 450

Query: 136 FFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANFA 195
           +FQLY++++RA++ +LV++AE  GF+ + LT D P  G+R  D+RN F+LPPH+ L N  
Sbjct: 451 WFQLYIHRNRAVSRQLVQQAEALGFQGLVLTADLPYTGKRRNDVRNGFRLPPHMKLKN-- 508

Query: 196 DMKDFAQVKGGAGASGLASY--VASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQR 253
                  ++G       + Y    + +D S+ W+DI WL+S+T LPI++KG++T EDA+ 
Sbjct: 509 -------LEGAFEGDDRSEYGLPPNSLDPSVTWDDIYWLRSLTHLPIVIKGILTKEDAEL 561

Query: 254 ALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALAL 313
           A+++G  GI +SNHG RQLDG  ATID L EV ++VR R+ V++D G+R+G+DV+KALAL
Sbjct: 562 AVRHGVQGIIVSNHGGRQLDGAPATIDALVEVVEAVRDRVEVYLDGGIRKGSDVLKALAL 621

Query: 314 GADAVLIGRPIVWGLAVDGEEGVYRLLSLL 343
           GA  V IGRP +WGLA  GEEG+  +L+ L
Sbjct: 622 GAKCVFIGRPALWGLAYKGEEGLQDVLTFL 651

gb|AAF10604.1| (S)-2-hydroxy-acid oxidase [Deinococcus radiodurans]
pir||H75446 (S)-2-hydroxy-acid oxidase - Deinococcus radiodurans (strain R1)
ref|NP_294755.1| (S)-2-hydroxy-acid oxidase [Deinococcus radiodurans R1]
(353 aa)

Score: 305 bits (782), Expect: 1.13133e-81
Length: 356, Idn/Pos/Gap = 170/234/8 (47%/65%/2%)

Query:  14 LNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQ  73
           LNL E    A   LP   + YY  GA+DE TLR+N E + RL+ RPR+L+DVS +D +  
Sbjct:   6 LNLREMEQAAAGVLPPAAFAYYTGGANDEHTLRENREGYARLKLRPRMLVDVSHIDTSTT  65

Query:  74 VMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGL 133
           V+G+ L+FP+ VAP A+  + HP+ E+ATARA A +G++M LS+ +  ++EDV+    G 
Sbjct:  66 VLGLPLAFPVGVAPCALHGLVHPDAEVATARAAASLGSLMTLSTMSHRTIEDVSDAAGG- 124

Query: 134 PKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLAN 193
             +FQLY+YKDR ++  LV+RAE AG RA+ LTVD P LGRREA IR    + P   L N
Sbjct: 125 QFWFQLYLYKDREVSRALVQRAEAAGARALVLTVDAPVLGRREAIIRTPVHIEPGTVLPN 184

Query: 194 FADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQR 253
                   +V G      L  Y  SL+D ++ WNDI WL+ IT LPI+LKG++TAED   
Sbjct: 185 IG-----PRVPGSEHLDDL-QYFDSLLDPAITWNDIGWLRGITGLPIVLKGLLTAEDVAL 238

Query: 254 ALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALAL 313
           A+Q+G   IW SNHG RQLD     +D L E+A++  GR  +++D GV RGTDV+KALAL
Sbjct: 239 AVQHGCH-IWASNHGGRQLDTAVTALDALPEIAEAANGRAEIYLDGGVTRGTDVLKALAL 297

Query: 314 GADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLVVR 369
           GA+AV + R +++GLA+ GE+G    L LL+DE +LAM LCG  +VS++  +L+ R
Sbjct: 298 GANAVFLARAVLYGLALAGEDGARHTLELLRDEVRLAMMLCGKTQVSELGPELIWR 353

emb|CAI23077.1| hydroxyacid oxidase 2 (long chain) [Homo sapiens]
(364 aa)

Score: 305 bits (781), Expect: 1.37068e-81
Length: 359, Idn/Pos/Gap = 157/226/11 (43%/62%/3%)

Query:   9 PATQPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRV  68
           P    + L ++   A+ +L      +   GADD  T  DN  AF+R+R RPR L DVS V
Sbjct:  12 PEMSLVCLTDFQAHAREQLSKSTRDFIEGGADDSITRDDNIAAFKRIRLRPRYLRDVSEV  71

Query:  69 DITKQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAA 128
           D    + G ++S P+ +APT    +  P+GE++TARA    G     S++A+ SLED+  
Sbjct:  72 DTRTTIQGEEISAPICIAPTGFHCLVWPDGEMSTARAAQAAGICYITSTFASCSLEDIVI 131

Query: 129 HVPGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPH 188
             P   ++FQLYV+ D  + ++L++R E  GF+A+ +T+DTP  G R  DIRNQ  L  +
Sbjct: 132 AAPEGLRWFQLYVHPDLQLNKQLIQRVESLGFKALVITLDTPVCGNRRHDIRNQ--LRRN 189

Query: 189 LSLANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTA 248
           L+L +    K     KG A    +  +  + I  SL WND++W +SITRLPI+LKG++T 
Sbjct: 190 LTLTDLQSPK-----KGNA----IPYFQMTPISTSLCWNDLSWFQSITRLPIILKGILTK 240

Query: 249 EDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVV 308
           EDA+ A+++   GI +SNHG RQLD V A+ID L EV  +V+G+I V++D GVR G DV+
Sbjct: 241 EDAELAVKHNVQGIIVSNHGGRQLDEVLASIDALTEVVAAVKGKIEVYLDGGVRTGNDVL 300

Query: 309 KALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLV 367
           KALALGA  + +GRPI+WGLA  GE GV  +L++L +EF  +M L GC+ V++I R+LV
Sbjct: 301 KALALGAKCIFLGRPILWGLACKGEHGVKEVLNILTNEFHTSMALTGCRSVAEINRNLV 359

emb|CAC19798.1| hydroxyacid oxidase 2 (long chain) [Homo sapiens]
gb|AAH20863.1| Hydroxyacid oxidase 2 [Homo sapiens]
sp|Q9NYQ3|HAOX2_HUMAN Hydroxyacid oxidase 2 (HAOX2) ((S)-2-hydroxy-acid oxidase, peroxisomal) (Long chain alpha-hydroxy acid oxidase) (Long-chain L-2-hydroxy acid oxidase)
gb|AAF40200.1| long-chain 2-hydroxy acid oxidase HAOX2 [Homo sapiens]
ref|NP_001005783.1| hydroxyacid oxidase 2 [Homo sapiens]
ref|NP_057611.1| hydroxyacid oxidase 2 [Homo sapiens]
(351 aa)

Score: 304 bits (778), Expect: 3.29168e-81
Length: 352, Idn/Pos/Gap = 156/224/11 (44%/63%/3%)

Query:  16 LAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVM  75
           L ++   A+ +L      +   GADD  T  DN  AF+R+R RPR L DVS VD    + 
Sbjct:   6 LTDFQAHAREQLSKSTRDFIEGGADDSITRDDNIAAFKRIRLRPRYLRDVSEVDTRTTIQ  65

Query:  76 GIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPK 135
           G ++S P+ +APT    +  P+GE++TARA    G     S++A+ SLED+    P   +
Sbjct:  66 GEEISAPICIAPTGFHCLVWPDGEMSTARAAQAAGICYITSTFASCSLEDIVIAAPEGLR 125

Query: 136 FFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANFA 195
           +FQLYV+ D  + ++L++R E  GF+A+ +T+DTP  G R  DIRNQ  L  +L+L +  
Sbjct: 126 WFQLYVHPDLQLNKQLIQRVESLGFKALVITLDTPVCGNRRHDIRNQ--LRRNLTLTDLQ 183

Query: 196 DMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQRAL 255
             K     KG A    +  +  + I  SL WND++W +SITRLPI+LKG++T EDA+ A+
Sbjct: 184 SPK-----KGNA----IPYFQMTPISTSLCWNDLSWFQSITRLPIILKGILTKEDAELAV 234

Query: 256 QYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALALGA 315
           ++   GI +SNHG RQLD V A+ID L EV  +V+G+I V++D GVR G DV+KALALGA
Sbjct: 235 KHNVQGIIVSNHGGRQLDEVLASIDALTEVVAAVKGKIEVYLDGGVRTGNDVLKALALGA 294

Query: 316 DAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLV 367
             + +GRPI+WGLA  GE GV  +L++L +EF  +M L GC+ V++I R+LV
Sbjct: 295 KCIFLGRPILWGLACKGEHGVKEVLNILTNEFHTSMALTGCRSVAEINRNLV 346

ref|ZP_00187505.2| COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Rubrobacter xylanophilus DSM 9941]
(349 aa)

Score: 301 bits (772), Expect: 1.71751e-80
Length: 366, Idn/Pos/Gap = 172/235/25 (46%/64%/6%)

Query:  12 QPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDIT  71
           +P+++ +Y   A+ R+    + Y  +GA+DE TLR+N  AF RLR  PRVL  VS  D+ 
Sbjct:   2 EPISVLDYEPLARERMHPAAWAYLCAGAEDEVTLRENRAAFERLRLVPRVLRGVSAPDLR  61

Query:  72 KQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVP 131
             V+G  +  P++VAP  +  +AHPEGE A+AR     GT+M +S+ ++ S+E+V+A   
Sbjct:  62 TTVLGTPVEAPVLVAPMGVHGLAHPEGECASARGAGEAGTLMAVSTVSSRSIEEVSACAT 121

Query: 132 GLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSL 191
           G P +FQLYVY+ R + ERLVRRAERAG RA+ LT D+P+ GR+E  +R    LPP    
Sbjct: 122 G-PLWFQLYVYRSRGLAERLVRRAERAGCRALVLTADSPRWGRKERFLRVAGSLPP---- 176

Query: 192 ANFADMKDFAQVKGGAGASGLASYVAS--LIDASLNWNDIAWLKSITRLPILLKGVVTAE 249
                         GA A+ + S V    L  A+L W D+AWL+S++ LP++LKGV+  E
Sbjct: 177 --------------GADAASIDSEVGEEDLAPAALTWEDVAWLRSVSSLPVVLKGVLHPE 222

Query: 250 DAQRALQYGADGIWISNHGARQLDGVTATIDCL----EEVAQSVRGRIPVFIDSGVRRGT 305
           DA  A+++GA GI +SNHG RQLDG  A+I+ L    E VA +  GR  V++D GVRRGT
Sbjct: 223 DAVLAVEHGAAGIVVSNHGGRQLDGAPASIEALPAVVEAVAGASGGRAEVYLDGGVRRGT 282

Query: 306 DVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRD 365
           DV+KALALGA AV +GRP++WGLAV G EGV R+L LL+ E + AM LCG   V  +  +
Sbjct: 283 DVLKALALGARAVFVGRPVLWGLAVGGAEGVRRVLGLLRGELEHAMALCGQASVGGLDPE 342

Query: 366 LVVRDA 371
           LV R A
Sbjct: 343 LVSRGA 348

gb|EAL21052.1| hypothetical protein CNBD4280 [Cryptococcus neoformans var. neoformans B-3501A]
gb|AAW42912.1| hypothetical protein CND02080 [Cryptococcus neoformans var. neoformans JEC21]
ref|XP_570219.1| hypothetical protein CND02080 [Cryptococcus neoformans var. neoformans JEC21]
(370 aa)

Score: 300 bits (768), Expect: 5.47754e-80
Length: 349, Idn/Pos/Gap = 162/219/10 (46%/62%/2%)

Query:  23 AKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGIDLSFP  82
           +K  LP MV+ +Y  GA D  T R+N EAF + R RPR+L+DV  +D++ +V G  ++ P
Sbjct:  20 SKKTLPQMVHEFYNGGAMDMITCRENVEAFNQYRIRPRILVDVGNIDMSVEVFGQKVAAP  79

Query:  83 LMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPG-LPKFFQLYV 141
           L  +PTA Q++AHP+GE+AT+ A ++ G  M LS+++TTS+EDV     G +P   QL V
Sbjct:  80 LGFSPTAFQKLAHPDGEIATSMAASKAGIPMCLSTYSTTSIEDVVTAGQGAIPYVMQLSV 139

Query: 142 YKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANFADMKDFA 201
            K R     ++RRAE+AG +A+ +TVD   LGRR  + RN F LP H+ L +     D+ 
Sbjct: 140 MKSRDANLEIIRRAEKAGCKALFVTVDCAVLGRRLNEARNNFTLPDHIELPHMPADCDWR 199

Query: 202 QVKGGAGASGLASYVASLIDASLNWNDIA-WLKSITRLPILLKGVVTAEDAQRALQYGAD 260
            +        +        DAS  W  +  W +S T++ I LKGV TAED   A++YG D
Sbjct: 200 NL--------VVEDDRLKYDASCTWKTLVDWARSHTKMQIWLKGVYTAEDVALAIEYGID 251

Query: 261 GIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALALGADAVLI 320
           G+ +SNHG RQLD VTAT+D L EV ++  GRIPV IDSG+RRGTD+ KALALGAD V I
Sbjct: 252 GVVVSNHGGRQLDSVTATLDALPEVVEAAAGRIPVHIDSGIRRGTDIFKALALGADHVWI 311

Query: 321 GRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLVVR 369
           GR ++WGLA DGE GV   ++LL DE +  M L GC  V  I R  + R
Sbjct: 312 GRAVIWGLAHDGEAGVSLAVNLLLDELRTTMVLAGCANVKQITRAHLAR 360

emb|CAG80943.1| unnamed protein product [Yarrowia lipolytica CLIB99]
ref|XP_502755.1| hypothetical protein [Yarrowia lipolytica]
(382 aa)

Score: 298 bits (764), Expect: 1.54141e-79
Length: 348, Idn/Pos/Gap = 160/217/13 (45%/62%/3%)

Query:  34 YYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQV--MGIDLSFPLMVAPTAMQ  91
           Y+ +G++D  TL +N+ AF  L+ R R +  V  +DI+ +V   G     P+ VAP+A  
Sbjct:  28 YWETGSNDLLTLAENQNAFNYLKIRARAMRGVGTIDISPKVELFGRKFRAPIGVAPSAYH  87

Query:  92 RMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFFQLYVYKDRAITERL 151
           +MA   GE  TA A       MGLSS++   LE+V    P    FFQLYV+K++  +E L
Sbjct:  88 QMADDSGECGTAAACQARNWPMGLSSFSNKPLEEVREAGPDAALFFQLYVFKNKKTSENL 147

Query: 152 VRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANFADMKDFAQVKGGAGASG 211
           V++AE+AGF+AIALTVDTP LG R AD+RN F+LP HLS  NF    D   +   A A  
Sbjct: 148 VKKAEKAGFKAIALTVDTPYLGNRYADVRNNFKLPSHLSARNFEGTTD-QPIDNAAEADS 206

Query: 212 LASYV---------ASLIDASLNWND-IAWLKSITRLPILLKGVVTAEDAQRALQYGADG 261
            A  +         A+++D  +NW + I WL+SIT + I +KGVVTAED   A++ G DG
Sbjct: 207 WARKIFNGEECPPDANVVDPDINWAETIPWLRSITNMQIWVKGVVTAEDTHAAIEAGVDG 266

Query: 262 IWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALALGADAVLIG 321
           IW+SNHG RQLD   ATID L EV ++  GR+P+ ID G+RRG DV K LALGAD V +G
Sbjct: 267 IWVSNHGGRQLDSGLATIDALPEVVEAAAGRVPIHIDGGIRRGGDVFKCLALGADFVWLG 326

Query: 322 RPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLVVR 369
           RP +WGL  DG+ GV  +  +++D+ KL M L G + V++I R  +VR
Sbjct: 327 RPAIWGLKYDGQAGVELMEQIIEDDLKLTMALAGTKTVAEINRSCLVR 374

ref|XP_533023.1| PREDICTED: similar to Hydroxyacid oxidase 2 (HAOX2) ((S)-2-hydroxy-acid oxidase, peroxisomal) (Long chain alpha-hydroxy acid oxidase) (Long-chain L-2-hydroxy acid oxidase) [Canis familiaris]
(513 aa)

Score: 297 bits (761), Expect: 2.95503e-79
Length: 370, Idn/Pos/Gap = 149/227/27 (40%/61%/7%)

Query:  16 LAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVM  75
           L ++  +A+  L    + Y   GAD+  T  DN  AF+R+R RPR L DV  VD    V 
Sbjct: 148 LTDFQAYAQKHLSKSTWDYIEGGADECFTRDDNITAFKRIRLRPRYLKDVQEVDTRTTVQ 207

Query:  76 GIDLSFPLMVAPTAMQRMAHPEGELATARAVAR------------------IGTVMGLSS 117
           G +++ P+ ++PT    +  P+GE++TAR + +                   G     S+
Sbjct: 208 GEEITAPICISPTGFHCLVWPDGEMSTARGMTQPHLEALFSGALNCAAAQAAGICYITST 267

Query: 118 WATTSLEDVAAHVPGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREA 177
           +A+ +LED+ A  P   ++FQLY+  D+ + ++LV++ E  GF+A+ +TVD P+LG R  
Sbjct: 268 YASCALEDIVATAPRGLRWFQLYMQSDKQLNKQLVQKVESLGFKALVITVDVPKLGNRRQ 327

Query: 178 DIRNQFQLPPHLSLANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITR 237
           DI+NQ  L  +L L +    K+          + +  +    IDAS  WND++WL+SITR
Sbjct: 328 DIQNQLDLKMNLLLKDLRSTKE---------RNPMPYFQMFPIDASFCWNDLSWLQSITR 378

Query: 238 LPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFI 297
           LPI+LKG++T EDA+ A+++   GI +SNHG RQLD V A+ID L EV  +V+G++ V++
Sbjct: 379 LPIILKGILTKEDAELAVKHNVHGIIVSNHGGRQLDDVLASIDALAEVVAAVKGKMEVYL 438

Query: 298 DSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQ 357
           D G+R G DV+KALALGA  V +GRPI+WGLA  GE GV  +L+++K+EF  +M L GC+
Sbjct: 439 DGGIRTGNDVLKALALGAKCVFLGRPILWGLAYKGEYGVEEVLNIIKNEFHTSMALTGCR 498

Query: 358 KVSDIRRDLV 367
            V++I +DL+
Sbjct: 499 SVAEINQDLI 508

pdb|1TB3|H Chain H, Crystal Structure Analysis Of Recombinant Rat Kidney Long- Chain Hydroxy Acid Oxidase
pdb|1TB3|G Chain G, Crystal Structure Analysis Of Recombinant Rat Kidney Long- Chain Hydroxy Acid Oxidase
pdb|1TB3|F Chain F, Crystal Structure Analysis Of Recombinant Rat Kidney Long- Chain Hydroxy Acid Oxidase
pdb|1TB3|E Chain E, Crystal Structure Analysis Of Recombinant Rat Kidney Long- Chain Hydroxy Acid Oxidase
pdb|1TB3|D Chain D, Crystal Structure Analysis Of Recombinant Rat Kidney Long- Chain Hydroxy Acid Oxidase
pdb|1TB3|C Chain C, Crystal Structure Analysis Of Recombinant Rat Kidney Long- Chain Hydroxy Acid Oxidase
pdb|1TB3|B Chain B, Crystal Structure Analysis Of Recombinant Rat Kidney Long- Chain Hydroxy Acid Oxidase
pdb|1TB3|A Chain A, Crystal Structure Analysis Of Recombinant Rat Kidney Long- Chain Hydroxy Acid Oxidase
gb|AAB20262.1| long chain alpha-hydroxy acid oxidase=FMN-dependent alpha-hydroxy acid-oxidizing enzyme {EC 1.1.3.15} [rats, kidney, Peptide, 352 aa]
(352 aa)

Score: 295 bits (755), Expect: 1.7329e-78
Length: 352, Idn/Pos/Gap = 153/222/9 (43%/63%/2%)

Query:  16 LAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVM  75
           LA++   A+ +L    + +    ADD  T  +N  AF+R+R RPR L D+S+VD    + 
Sbjct:   5 LADFKAHAQKQLSKTSWDFIEGEADDGITYSENIAAFKRIRLRPRYLRDMSKVDTRTTIQ  64

Query:  76 GIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPK 135
           G ++S P+ ++PTA   +A P+GE +TARA         +SS+A+ SLED+ A  P   +
Sbjct:  65 GQEISAPICISPTAFHSIAWPDGEKSTARAAQEANICYVISSYASYSLEDIVAAAPEGFR 124

Query: 136 FFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANFA 195
           +FQLY+  D    +++V+RAE  GF+A+ +T+DTP LG R  D RNQ  L  ++ L +  
Sbjct: 125 WFQLYMKSDWDFNKQMVQRAEALGFKALVITIDTPVLGNRRRDKRNQLNLEANILLKDLR 184

Query: 196 DMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQRAL 255
            +K+    +         S   S   AS  WND++ L+SITRLPI+LKG++T EDA+ A+
Sbjct: 185 ALKEEKPTQ---------SVPVSFPKASFCWNDLSLLQSITRLPIILKGILTKEDAELAM 235

Query: 256 QYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALALGA 315
           ++   GI +SNHG RQLD V+A+ID L EV  +V+G+I V++D GVR GTDV+KALALGA
Sbjct: 236 KHNVQGIVVSNHGGRQLDEVSASIDALREVVAAVKGKIEVYMDGGVRTGTDVLKALALGA 295

Query: 316 DAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLV 367
             + +GRPI+WGLA  GE+GV  +L +L  E    M L GCQ V++I  DL+
Sbjct: 296 RCIFLGRPILWGLACKGEDGVKEVLDILTAELHRCMTLSGCQSVAEISPDLI 347

ref|NP_114471.1| hydroxyacid oxidase 3 (medium-chain) [Rattus norvegicus]
emb|CAA47629.1| (S)-2-hydroxy-acid oxidase [Rattus norvegicus]
gb|AAH78781.1| Hao2 protein [Rattus norvegicus]
sp|Q07523|HAOX3_RAT Hydroxyacid oxidase 3 (HAOX3) ((S)-2-hydroxy-acid oxidase, peroxisomal) (Long chain alpha-hydroxy acid oxidase) (Long-chain L-2-hydroxy acid oxidase)
(353 aa)

Score: 295 bits (755), Expect: 1.77683e-78
Length: 352, Idn/Pos/Gap = 153/222/9 (43%/63%/2%)

Query:  16 LAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVM  75
           LA++   A+ +L    + +    ADD  T  +N  AF+R+R RPR L D+S+VD    + 
Sbjct:   6 LADFKAHAQKQLSKTSWDFIEGEADDGITYSENIAAFKRIRLRPRYLRDMSKVDTRTTIQ  65

Query:  76 GIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPK 135
           G ++S P+ ++PTA   +A P+GE +TARA         +SS+A+ SLED+ A  P   +
Sbjct:  66 GQEISAPICISPTAFHSIAWPDGEKSTARAAQEANICYVISSYASYSLEDIVAAAPEGFR 125

Query: 136 FFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANFA 195
           +FQLY+  D    +++V+RAE  GF+A+ +T+DTP LG R  D RNQ  L  ++ L +  
Sbjct: 126 WFQLYMKSDWDFNKQMVQRAEALGFKALVITIDTPVLGNRRRDKRNQLNLEANILLKDLR 185

Query: 196 DMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQRAL 255
            +K+    +         S   S   AS  WND++ L+SITRLPI+LKG++T EDA+ A+
Sbjct: 186 ALKEEKPTQ---------SVPVSFPKASFCWNDLSLLQSITRLPIILKGILTKEDAELAM 236

Query: 256 QYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALALGA 315
           ++   GI +SNHG RQLD V+A+ID L EV  +V+G+I V++D GVR GTDV+KALALGA
Sbjct: 237 KHNVQGIVVSNHGGRQLDEVSASIDALREVVAAVKGKIEVYMDGGVRTGTDVLKALALGA 296

Query: 316 DAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLV 367
             + +GRPI+WGLA  GE+GV  +L +L  E    M L GCQ V++I  DL+
Sbjct: 297 RCIFLGRPILWGLACKGEDGVKEVLDILTAELHRCMTLSGCQSVAEISPDLI 348

ref|XP_473943.1| OSJNBa0053K19.9 [Oryza sativa (japonica cultivar-group)]
emb|CAE03501.2| OSJNBa0053K19.9 [Oryza sativa (japonica cultivar-group)]
(276 aa)

Score: 292 bits (748), Expect: 9.27101e-78
Length: 273, Idn/Pos/Gap = 145/205/3 (53%/75%/1%)

Query:  15 NLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQV  74
           N+ EY   AK +LP MVY +YA  A+D+ TLR+N EAF R+ F+P VL+DVS +D++  V
Sbjct:   6 NVCEYEELAKHKLPKMVYDFYAVDAEDQWTLRENSEAFSRILFQPVVLVDVSCIDMSMSV  65

Query:  75 MGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLP 134
           +G ++S P+M+APTA+ ++AHPEGELATARA A   T+M LSSW++ S+E+V    PG+ 
Sbjct:  66 LGYNISMPIMIAPTALHKLAHPEGELATARAAAAAETIMTLSSWSSCSIEEVNLAGPGV- 124

Query: 135 KFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANF 194
           +FFQL +YKDR + ++L++RAE+AG++AI LTVD P LGRREAD++N+F LP ++ L  F
Sbjct: 125 RFFQLSIYKDRNLVQQLIQRAEKAGYKAIVLTVDAPWLGRREADVKNRFTLPQNVMLKIF 184

Query: 195 ADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQRA 254
             + D  ++    G SGLA+YVAS ID S +W DI WL+++T LP+L+KG++TA+D + A
Sbjct: 185 EGL-DQGKIDETNG-SGLAAYVASQIDRSFSWKDIKWLQTVTSLPVLVKGIITAQDTRIA 242

Query: 255 LQYGADGIWISNHGARQLDGVTATIDCLEEVAQ 287
           ++YGA GI +SNHG RQLD + ATI CLEE+  
Sbjct: 243 IEYGAAGIIMSNHGGRQLDYLPATISCLEELCH 275

gb|AAF14000.1| long-chain L-2-hydroxy acid oxidase [Homo sapiens]
(351 aa)

Score: 292 bits (747), Expect: 1.40705e-77
Length: 352, Idn/Pos/Gap = 152/220/11 (43%/62%/3%)

Query:  16 LAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVM  75
           L ++   A+ +L      +   GADD  T  DN  AF+R+R RPR L DVS VD    + 
Sbjct:   6 LTDFQAHAREQLSKSTRDFIEGGADDSITRDDNIAAFKRIRLRPRYLRDVSEVDTRTTIQ  65

Query:  76 GIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPK 135
           G ++S  + +APT    +  P+GE++TARA    G     S++A+ SLED+    P   +
Sbjct:  66 GEEISALICIAPTGYHCLVWPDGEMSTARAAQAAGICYITSTFASCSLEDIVIAAPEGLR 125

Query: 136 FFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANFA 195
           +FQLYV+ D  + ++L++R E  GF+A+ +T+DTP  G R  DIRNQ  L  +L+L +  
Sbjct: 126 WFQLYVHPDLQLNKQLIQRVESLGFKALVITLDTPVCGNRRHDIRNQ--LRRNLTLTDLQ 183

Query: 196 DMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQRAL 255
             K     KG A    +  +  + I  SL WND++W +SITRLPI+LKG++T EDA+ A+
Sbjct: 184 SPK-----KGNA----IPYFQMTPISTSLCWNDLSWFQSITRLPIILKGILTKEDAELAV 234

Query: 256 QYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALALGA 315
           ++   GI +SNHG RQLD V A+ID L EV  +V+G+I V++D GVR G DV+KALA   
Sbjct: 235 KHNVQGIIVSNHGGRQLDEVLASIDALTEVVAAVKGKIEVYLDGGVRTGNDVLKALAHED 294

Query: 316 DAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLV 367
             + +GRPI+WGLA  GE GV  +L++L +EF  +M L GC+ V++I R+LV
Sbjct: 295 KCIFLGRPILWGLACKGEHGVKEVLNILTNEFHTSMALTGCRSVAEINRNLV 346

emb|CAG85782.1| unnamed protein product [Debaryomyces hansenii CBS767]
ref|XP_457751.1| unnamed protein product [Debaryomyces hansenii]
(378 aa)

Score: 290 bits (741), Expect: 6.86755e-77
Length: 356, Idn/Pos/Gap = 153/217/11 (42%/60%/3%)

Query:  16 LAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVM  75
           +A+  L A  +LP MV  +Y  G+ D  T+R+N+ A+ R   RPRV++DV+ VD +   +
Sbjct:  14 IADLELEANKKLPPMVRDFYGGGSMDLNTVRENKSAYDRYSLRPRVMVDVTEVDTSTTCL  73

Query:  76 GIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHV--PGL 133
           G +++FPL  +P+A   +AHP+ E  T+RA A+    M LSSW  TS + VA      G+
Sbjct:  74 GSNVAFPLGFSPSANHGLAHPDAERGTSRAAAKKKINMALSSWTNTSPKVVAEQGKDAGI 133

Query: 134 PKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLAN 193
               QL   KD+ +T  ++R AE  G++AI L+VD P LGRR  +++N F LP +     
Sbjct: 134 SYAHQLSAVKDQDVTMSIIRNAEACGYKAIFLSVDCPLLGRRLNEMKNTFTLPSNCKFPC 193

Query: 194 FADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQR 253
           +  +K         G   ++S   +  + +L W+ I  LK  T + I LKG++T EDA+ 
Sbjct: 194 YPFIK---------GGDMVSSDDRTQYETTLTWSYIKELKKKTNMEIWLKGILTGEDAEM 244

Query: 254 ALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALAL 313
           A+  GADGI +SNHG RQLDG  +T+D L +V  +V GRIPV ID G+RRG+D+ KALAL
Sbjct: 245 AVNAGADGIIVSNHGGRQLDGALSTLDALPDVVAAVNGRIPVHIDGGIRRGSDIFKALAL 304

Query: 314 GADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLVVR 369
           GAD   +GR  VWGLA  GEEGV   L++L DEF+L M L GC  V DI+ + + R
Sbjct: 305 GADHCWVGRVAVWGLAYKGEEGVSIALNILHDEFRLVMALMGCTSVKDIKPEHLAR 360

emb|CAG79819.1| unnamed protein product [Yarrowia lipolytica CLIB99]
ref|XP_504224.1| hypothetical protein [Yarrowia lipolytica]
(493 aa)

Score: 289 bits (739), Expect: 1.10497e-76
Length: 365, Idn/Pos/Gap = 147/224/15 (40%/61%/4%)

Query:   9 PATQPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRV  68
           P +Q  N  ++   A+  +    + YY+SG+DDE T+R+N  AF ++ FRPRVL+DV  V
Sbjct: 103 PLSQIFNSFDFEYVARHTMSPNAWAYYSSGSDDEITVRENHRAFHKIWFRPRVLVDVKNV 162

Query:  69 DITKQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVA- 127
           DI+  ++G   S P  +  TA+ ++ HPEGE+   R   ++  +  + + A+ S +++  
Sbjct: 163 DISTTMLGTKSSVPFYITATALGKLGHPEGEVVLTRGADKMDVIQMIPTLASCSFDEIVD 222

Query: 128 AHVPGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPP 187
           A      ++ QLYV  DR +T+++V+ AE+ G + + +TVD PQLGRRE D+R +F   P
Sbjct: 223 AATDKQTQWMQLYVNMDREVTKKIVQHAEKRGVKGLFITVDAPQLGRREKDMRTKFG-DP 281

Query: 188 HLSLANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVT 247
              +    D  D +Q        G A  ++S ID SL+W DI W +SIT++PI+LKGV  
Sbjct: 282 GAQVQQSDDSVDRSQ--------GAARAISSFIDPSLSWKDIPWFQSITKMPIILKGVQC 333

Query: 248 AEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGR-----IPVFIDSGVR 302
           AEDA +A++Y  DGI +SNHG RQL+    +I+ L EV  ++R +     I V+ID G+R
Sbjct: 334 AEDALKAVEYKVDGILLSNHGGRQLEFARPSIEVLVEVMAALRAKGWQDYIEVYIDGGIR 393

Query: 303 RGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDI 362
           R TDV+KAL LGA  V IGRP ++ ++  GE+GV  L+ LLKDE ++ M+L G  K+ D+
Sbjct: 394 RATDVIKALCLGAKGVGIGRPFLYAMSTYGEDGVCHLIQLLKDEMEMNMRLIGATKIEDL 453

Query: 363 RRDLV 367
              +V
Sbjct: 454 NPSMV 458

gb|AAB80700.1| glycolate oxidase [Arabidopsis thaliana]
(259 aa)

Score: 288 bits (738), Expect: 1.46742e-76
Length: 256, Idn/Pos/Gap = 144/198/3 (56%/77%/1%)

Query: 119 ATTSLEDVAAHVPGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREAD 178
           AT+S+E +A+  PG+ +FFQLYVYK+R + E+LVR+AE+AGF+AIALTV+TP+LG +++D
Sbjct:   1 ATSSVEKIASTGPGI-RFFQLYVYKNRKVVEQLVRKAEKAGFKAIALTVNTPRLGPKKSD  59

Query: 179 IRNQFQLPPHLSLANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRL 238
           I+N+F LPP+L+L NF  + D  ++   A  SGLASYVA  ID +L+W DI WL++IT +
Sbjct:  60 IKNRFTLPPNLTLKNFEGL-DLGKMDE-ANDSGLASYVAGQIDRTLSWKDIQWLQTITNM 117

Query: 239 PILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFID 298
           PIL+KGV+T EDA+ A+Q GA GI +SNHGARQLD V ATI  LEEV ++ +G +PVF+D
Sbjct: 118 PILVKGVLTGEDARIAIQAGAAGIIVSNHGARQLDYVPATISALEEVVKATQGGVPVFLD 177

Query: 299 SGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQK 358
            GVRRGTDV KALALG   + IGRP+V+ LA +GE GV ++L +L+DEF+L M L GC+ 
Sbjct: 178 GGVRRGTDVFKALALGTSGIFIGRPVVFALAAEGEAGVKKVLQMLRDEFELTMALSGCRS 237

Query: 359 VSDIRRDLVVRDAFAP 374
           +S+I R+ +V +   P
Sbjct: 238 ISEITRNHIVTEWDIP 253

emb|CAA34183.1| L-lactate:cytochrome c oxidoreductase preprotein [Pichia anomala]
sp|P09437|CYB2_HANAN Cytochrome b2, mitochondrial precursor (L-lactate dehydrogenase [Cytochrome]) (L-lactate ferricytochrome C oxidoreductase) (L-LCR)
(573 aa)

Score: 286 bits (733), Expect: 6.11219e-76
Length: 365, Idn/Pos/Gap = 149/229/16 (40%/62%/4%)

Query:   9 PATQPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRV  68
           P +Q +NL ++   A+  LP     YY S ADDE TLR+N  A+ R+ F P++LIDV  V
Sbjct: 183 PLSQMINLHDFETIARQILPPPALAYYCSAADDEVTLRENHNAYHRIFFNPKILIDVKDV 242

Query:  69 DITKQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVA- 127
           DI+ +  G   S P  ++ TA+ ++ HPEGE+A A+   R   V  +S+ A+ S +++A 
Sbjct: 243 DISTEFFGEKTSAPFYISATALAKLGHPEGEVAIAKGAGREDVVQMISTLASCSFDEIAD 302

Query: 128 AHVPGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPP 187
           A +PG  +++QLYV  DR+ITE+ VR AE  G + + +TVD P LGRRE D++ +F+   
Sbjct: 303 ARIPGQQQWYQLYVNADRSITEKAVRHAEERGMKGLFITVDAPSLGRREKDMKMKFEADS 362

Query: 188 HLSLANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVT 247
            +      D +D  + +G + A      ++S ID SL+W DIA++KSIT++PI++KGV  
Sbjct: 363 DVQ----GDDEDIDRSQGASRA------LSSFIDPSLSWKDIAFIKSITKMPIVIKGVQR 412

Query: 248 AEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGR-----IPVFIDSGVR 302
            ED   A ++G  G+ +SNHG RQLD   A ++ L EV   ++ R     I +F+D GVR
Sbjct: 413 KEDVLLAAEHGLQGVVLSNHGGRQLDYTRAPVEVLAEVMPILKERGLDQKIDIFVDGGVR 472

Query: 303 RGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDI 362
           RGTDV+KAL LGA  V +GRP ++ ++  G++GV + + LLKDE ++ M+L G  K+ ++
Sbjct: 473 RGTDVLKALCLGAKGVGLGRPFLYAMSSYGDKGVTKAIQLLKDEIEMNMRLLGVNKIEEL 532

Query: 363 RRDLV 367
             +L+
Sbjct: 533 TPELL 537

gb|EAA70224.1| hypothetical protein FG00145.1 [Gibberella zeae PH-1]
ref|XP_380321.1| hypothetical protein FG00145.1 [Gibberella zeae PH-1]
(424 aa)

Score: 285 bits (730), Expect: 1.30602e-75
Length: 371, Idn/Pos/Gap = 164/232/15 (44%/62%/4%)

Query:  12 QPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDIT  71
           +P+ + E    A+  LPA V+ YYA GADD+ T   N+E +R L  RPR+L ++S +D +
Sbjct:   7 KPITVDEIKALAQKILPAYVWRYYADGADDQVTTLRNQEVYRTLVIRPRILRNISSIDTS  66

Query:  72 KQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVP 131
            ++ G     P+ +AP+A QR+A   GE+  ARA     T + LSS ATTSLEDVA  +P
Sbjct:  67 TRIFGKYYDIPIAIAPSAYQRLAGYNGEIDVARAAFARRTNICLSSNATTSLEDVAQALP 126

Query: 132 G----LPK-FFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLP 186
                 PK +FQLY  + R IT+ L+ RAERAG+ A+ LTVDT  +G R  + +N  +LP
Sbjct: 127 KRDGKYPKPWFQLYFVRSRDITKELIERAERAGYEALVLTVDTTTMGNRLHERKNPLKLP 186

Query: 187 PHLSLANFADMKDFAQVKG----GAGASGLASYVAS-----LIDASLNWND-IAWLKSIT 236
             LS+AN   +K     KG     A  +  A+ +       LID++L W + I WL+S T
Sbjct: 187 ADLSMANMTTIKGGGASKGRLILNAETAEEAAKIEREHSDLLIDSALTWAETIPWLRSQT 246

Query: 237 RLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVF 296
            + I+LKG++TAEDA  +++ G D I +SNHG RQLD V AT++ L EV+ +V+GRIPV 
Sbjct: 247 NMKIILKGILTAEDALLSVEAGVDAIIVSNHGGRQLDSVPATLEALPEVSDAVKGRIPVL 306

Query: 297 IDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGC 356
            D G+ +G+DV KALALGAD  L+G+  +WGLAV+G++GV  +L++L+ E    M L G 
Sbjct: 307 YDGGISKGSDVFKALALGADLCLLGQSALWGLAVNGQQGVETVLNILERELWRTMVLSGA 366

Query: 357 QKVSDIRRDLV 367
             + DI R LV
Sbjct: 367 AAIKDISRYLV 377

gb|EAA58832.1| hypothetical protein AN3901.2 [Aspergillus nidulans FGSC A4]
ref|XP_408038.1| hypothetical protein AN3901.2 [Aspergillus nidulans FGSC A4]
(493 aa)

Score: 285 bits (729), Expect: 1.60894e-75
Length: 368, Idn/Pos/Gap = 147/225/20 (39%/61%/5%)

Query:   9 PATQPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRV  68
           P +   NL ++   A++ +    + YY+SGADDE T+R+N +AF+++ FRPRVL+DV  V
Sbjct: 107 PLSACYNLLDFETVARSVMKKTAWAYYSSGADDEITMRENHQAFQKIWFRPRVLVDVENV 166

Query:  69 DITKQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVA- 127
           D + +++G   S P  V  TA+ ++ +PEGE+   RA      +  + + A+ S +++  
Sbjct: 167 DFSTKMLGTKCSIPFYVTATALGKLGNPEGEVVLTRAAHDHDVIQMIPTLASCSFDEIVD 226

Query: 128 AHVPGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPP 187
           A      ++ QLYV KDRAIT+R++  AE  G + + +TVD PQLGRRE D+R++     
Sbjct: 227 ARRGDQVQWLQLYVNKDRAITKRIIEHAEARGCKGLFITVDAPQLGRREKDMRSK----- 281

Query: 188 HLSLANFADMKDFAQVKGGAG---ASGLASYVASLIDASLNWNDIAWLKSITRLPILLKG 244
                 F+D+    Q  GG     + G A  ++S ID SL+W DI W +S+T++PI+LKG
Sbjct: 282 ------FSDVGSNVQATGGDEVDRSQGAARAISSFIDPSLSWKDIPWFQSVTKMPIVLKG 335

Query: 245 VVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVR-----GRIPVFIDS 299
           V   ED  RA++ G  G+ +SNHG RQLD   + I+ L +V   +R      RI +FID 
Sbjct: 336 VQCVEDVLRAVEAGVQGVVLSNHGGRQLDTAPSGIEVLAQVMPILRERGWENRIEIFIDG 395

Query: 300 GVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKV 359
           G+RR TD++KAL LGA  V IGRP ++ ++  G+ GV R + LLKDE ++ M+L G QK+
Sbjct: 396 GIRRATDILKALCLGAKGVGIGRPFLFAMSAYGQPGVNRAMQLLKDELEMNMRLIGAQKI 455

Query: 360 SDIRRDLV 367
           +D+   +V
Sbjct: 456 ADLNPSMV 463

gb|AAC32392.1| glycolate oxidase [Medicago sativa]
pir||T09388 (S)-2-hydroxy-acid oxidase (EC 1.1.3.15) - alfalfa  (fragment)
(283 aa)

Score: 284 bits (727), Expect: 2.74443e-75
Length: 265, Idn/Pos/Gap = 147/197/3 (55%/74%/1%)

Query: 110 GTVMGLSSWATTSLEDVAAHVPGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDT 169
           GT+M LSSWAT+S+E+VA+  PG+ +FFQLYVYKDR +  +LVRRAE+AGF+AIALTVDT
Sbjct:  12 GTIMTLSSWATSSVEEVASTGPGI-RFFQLYVYKDRNVVAQLVRRAEKAGFKAIALTVDT  70

Query: 170 PQLGRREADIRNQFQLPPHLSLANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDI 229
           P+LGRREADI+N+F LPP L+L NF  + +  ++   A  SGLASYVA  ++ +L+W D+
Sbjct:  71 PRLGRREADIKNRFVLPPFLTLKNFEGL-NLGKMDQ-ANDSGLASYVAGQMNRTLSWKDV 128

Query: 230 AWLKSITRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSV 289
             L++IT LPIL+KGV+TAED + A+Q GA GI   NHGARQLD V       +EV ++ 
Sbjct: 129 KGLQNITSLPILVKGVLTAEDTRLAVQSGAAGIIGPNHGARQLDYVPPNNKGFKEVVKAA 188

Query: 290 RGRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKL 349
           +GR+PVF+D GV RGT+V KALALGA  + IGRP+V+ L  +GE GV ++L +L+DEF+L
Sbjct: 189 QGRVPVFLDGGVPRGTNVFKALALGASGIFIGRPVVYSLPAEGEAGVRKVLQMLRDEFEL 248

Query: 350 AMQLCGCQKVSDIRRDLVVRDAFAP 374
            M L GC+ + +I  D +V D   P
Sbjct: 249 TMALSGCRSLKEITSDHIVADWDTP 273

emb|CAD91196.1| putative hydroxymandelate oxidase [Nonomuraea sp. ATCC 39727]
(366 aa)

Score: 284 bits (726), Expect: 3.3529e-75
Length: 348, Idn/Pos/Gap = 158/217/2 (45%/62%/0%)

Query:  13 PLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITK  72
           P+ LAEY   A   LPA V  +   G+  EQTLR N  AF R+   PRVL DVS      
Sbjct:   5 PVCLAEYEEIAAKVLPADVRDFIDGGSGREQTLRANRAAFDRVFLVPRVLQDVSACSTRA  64

Query:  73 QVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPG 132
            ++G   + P+ VAP A  R+ HP+GELATARA    G    +S+ ++  +EDV A   G
Sbjct:  65 TLLGHPATMPVAVAPVAYHRLVHPDGELATARAARDAGVPFTVSTLSSVPVEDVTAL--G 122

Query: 133 LPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLA 192
              +FQLY  ++ A T  L+RRAE AG RA+ LT+D P +GRR  DIRN+F+LPPH+   
Sbjct: 123 GHVWFQLYCLREHAATLGLIRRAEDAGCRALMLTLDVPWMGRRPRDIRNRFRLPPHVRPV 182

Query: 193 NFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQ 252
           +          +G +G S LA++ A  + A+++W+ +  L++ + LP+++KG++  EDA+
Sbjct: 183 HLTANSGTEAHRGASGGSALAAHTAMELSAAVDWSYLETLRAASGLPLVVKGILHPEDAR 242

Query: 253 RALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALA 312
           RA   G DGI +SNHG RQLDG  A++D L  VA+SV GR  + +D GVR G DV+KALA
Sbjct: 243 RAADLGIDGIVVSNHGGRQLDGAVASLDALPGVAESVGGRCEIMLDGGVRSGADVLKALA 302

Query: 313 LGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVS 360
           LGA  VL+GRP++WGLA DGE GV  +L LL  E +  + L GC  V+
Sbjct: 303 LGASGVLVGRPVIWGLAADGERGVRTVLGLLGAEIEDGLGLAGCGDVA 350

emb|CAB96380.1| long chain 2-hydroxy acid oxidase [Mus musculus]
(353 aa)

Score: 283 bits (723), Expect: 8.05198e-75
Length: 354, Idn/Pos/Gap = 149/220/9 (42%/62%/2%)

Query:  14 LNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQ  73
           L LA++   A+ +L    + +    ADD  T  DN  AFRR+R RPR L DVS++D    
Sbjct:   4 LCLADFKAQAQKQLSKTSWDFIEGEADDGITYNDNLAAFRRIRLRPRYLRDVSKIDTRTT  63

Query:  74 VMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGL 133
           + G +++ P+ ++PTA   +A  +GE +TA+A  +      +SS+A+ ++ED+ A  PG 
Sbjct:  64 IQGQEINAPICISPTAFHSIAWADGEKSTAKAAQKANICYVISSYASYTVEDIVAAAPGG 123

Query: 134 PKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLAN 193
             +FQLYV  D  I +++V+R E  GF+A+ +TVD P LG R  + R    L  ++ L +
Sbjct: 124 LHWFQLYVQPDWDINKQMVQRIEALGFKALVVTVDAPVLGHRRGNXRXLLDLEANIKLKD 183

Query: 194 FADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQR 253
                       G   SGL + + S+  +S  WND+  L+S+TRLPI+LKG++T EDA+ 
Sbjct: 184 LR--------SPGESKSGLPTPL-SMPSSSSCWNDLPLLQSMTRLPIILKGILTKEDAEL 234

Query: 254 ALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALAL 313
           A+++   GI +SNHG RQLD V A+ID L EV  +V G+I V++D GVR G DV+KALAL
Sbjct: 235 AVKHNIXGIIVSNHGGRQLDEVPASIDALREVVAAVNGKIEVYMDGGVRTGNDVLKALAL 294

Query: 314 GADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLV 367
           GA  + +GRPI+WGLA  GE+GV  +L +LK+E    M L GC+ V++I  DL+
Sbjct: 295 GARCIFLGRPIIWGLACKGEDGVKEVLDILKEELHTCMALSGCRSVAEISPDLI 348

gb|EAA74045.1| hypothetical protein FG05328.1 [Gibberella zeae PH-1]
ref|XP_385504.1| hypothetical protein FG05328.1 [Gibberella zeae PH-1]
(502 aa)

Score: 283 bits (723), Expect: 8.39501e-75
Length: 369, Idn/Pos/Gap = 146/225/21 (39%/60%/5%)

Query:   1 MVEKPAVNPATQPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPR  60
           M +KP +   +Q  NL ++   A+  +  + +GYY+S ADDE T+R+N  AF R+ FRP+
Sbjct:  99 MEQKPLL---SQCYNLFDFEAVARRVMSKVAWGYYSSAADDEITMRENHSAFHRIWFRPQ 155

Query:  61 VLIDVSRVDITKQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWAT 120
           +L+DV  +D +  ++G     P+ V  TA+ ++ +PEGE+   RA A+   +  + + A+
Sbjct: 156 ILVDVENIDFSTTMLGTKTDIPVYVTATALGKLGNPEGEVVLTRAAAKHNVIQMIPTLAS 215

Query: 121 TSLEDVA-AHVPGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADI 179
            S +++  A      ++ QLYV KDRAIT+++V+ AE+ G + + +TVD PQLGRRE D+
Sbjct: 216 CSFDEIVDAKAGDQVQWLQLYVNKDRAITKKIVQHAEKRGCKGLFITVDAPQLGRREKDM 275

Query: 180 RNQFQLP-PHLSLANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRL 238
           R++F  P  H+      D            + G A  +++ ID +L+W DIAW +SIT +
Sbjct: 276 RSKFTDPGSHVQEGTDTD-----------NSQGAARAISTFIDPALSWKDIAWFQSITSM 324

Query: 239 PILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGR-----I 293
           PI+LKGV   ED  +A+ YG  G+ +SNHG RQL+   + I+ L E    +R R     I
Sbjct: 325 PIILKGVQRVEDVLKAIDYGCQGVVLSNHGGRQLEFARSAIEVLAETMPILRERGLENKI 384

Query: 294 PVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQL 353
            +FID G+RRGTD++KAL LGA  V IGRP ++ ++  GE GV R + LLKDE ++ M+L
Sbjct: 385 EIFIDGGIRRGTDILKALCLGARGVGIGRPFLYAMSTYGEAGVIRAMQLLKDELEMNMRL 444

Query: 354 CGCQKVSDI 362
            G  K+ D+
Sbjct: 445 IGASKIEDL 453

sp|Q9NYQ2|HAOX3_MOUSE Hydroxyacid oxidase 3 (HAOX3) ((S)-2-hydroxy-acid oxidase, peroxisomal) (Medium chain alpha-hydroxy acid oxidase) (Medium-chain L-2-hydroxy acid oxidase)
gb|AAF40201.1| medium-chain 2-hydroxy acid oxidase HAOX3 [Homo sapiens]
dbj|BAC37452.1| unnamed protein product [Mus musculus]
gb|AAF81795.1| long-chain L-2-hydroxy acid oxidase [Mus musculus]
(353 aa)

Score: 281 bits (720), Expect: 1.91762e-74
Length: 354, Idn/Pos/Gap = 149/221/9 (42%/62%/2%)

Query:  14 LNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQ  73
           L LA++   A+ +L    + +    ADD  T  DN  AFRR+R RPR L DVS++D    
Sbjct:   4 LCLADFKAQAQKQLSKTSWDFIEGEADDGITYNDNLAAFRRIRLRPRYLRDVSKIDTRTT  63

Query:  74 VMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGL 133
           + G +++ P+ ++PTA   +A  +GE +TA+A  +      +SS+A+ ++ED+ A  PG 
Sbjct:  64 IQGQEINAPICISPTAFHSIAWADGEKSTAKAAQKANICYVISSYASYTVEDIVAAAPGG 123

Query: 134 PKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLAN 193
             +FQLYV  D  I +++V+R E  GF+A+ +TVD P LG R  + R+   L  ++ L +
Sbjct: 124 LHWFQLYVQPDWDINKQMVQRIEALGFKALVVTVDAPVLGNRRGNKRSLLDLEANIKLKD 183

Query: 194 FADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQR 253
                       G   SGL + + S+  +S  WND+  L+S+TRLPI+LKG++T EDA+ 
Sbjct: 184 LR--------SPGESKSGLPTPL-SMPSSSSCWNDLPLLQSMTRLPIILKGILTKEDAEL 234

Query: 254 ALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALAL 313
           A+++   GI +SNHG RQLD V A+ID L EV  +V G+I V++D GVR G DV+KALAL
Sbjct: 235 AVKHNIRGIIVSNHGGRQLDEVPASIDALREVVAAVNGKIEVYMDGGVRTGNDVLKALAL 294

Query: 314 GADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLV 367
           GA  + +GRPI+WGLA  GE+GV  +L +LK+E    M L GC+ V++I  DL+
Sbjct: 295 GARCIFLGRPIIWGLACKGEDGVKEVLDILKEELHTCMALSGCRSVAEISPDLI 348

ref|NP_062418.2| hydroxyacid oxidase (glycolate oxidase) 3 [Mus musculus]
gb|AAH27754.1| Hydroxyacid oxidase (glycolate oxidase) 3 [Mus musculus]
(353 aa)

Score: 281 bits (719), Expect: 2.34277e-74
Length: 354, Idn/Pos/Gap = 149/220/9 (42%/62%/2%)

Query:  14 LNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQ  73
           L LA++   A+ +L    + +    ADD  T  DN  AFRR+R RPR L DVS++D    
Sbjct:   4 LCLADFKAQAQKQLSKTSWDFIEGEADDGITYNDNLAAFRRIRLRPRYLRDVSKIDTRTT  63

Query:  74 VMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGL 133
           + G +++ P+ ++PTA   +A  +GE +TA+A  +      +SS+A+ ++ED+ A  PG 
Sbjct:  64 IQGQEINAPICISPTAFHSIAWADGEKSTAKAAQKANICYVISSYASYTVEDIVAAAPGG 123

Query: 134 PKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLAN 193
             +FQLYV  D  I +++V+R E  GF+A+ +TVD P LG R  + R+   L  ++ L +
Sbjct: 124 LHWFQLYVQPDWDINKQMVQRIEALGFKALVVTVDAPVLGNRRGNKRSLLDLEANIKLKD 183

Query: 194 FADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQR 253
                       G   SGL + + S+   S  WND+  L+S+TRLPI+LKG++T EDA+ 
Sbjct: 184 LR--------SPGESKSGLPTPL-SMPSTSSCWNDLPLLQSMTRLPIILKGILTKEDAEL 234

Query: 254 ALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALAL 313
           A+++   GI +SNHG RQLD V A+ID L EV  +V G+I V++D GVR G DV+KALAL
Sbjct: 235 AVKHNIRGIIVSNHGGRQLDEVPASIDALREVVAAVNGKIEVYMDGGVRTGNDVLKALAL 294

Query: 314 GADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLV 367
           GA  + +GRPI+WGLA  GE+GV  +L +LK+E    M L GC+ V++I  DL+
Sbjct: 295 GARCIFLGRPIIWGLACKGEDGVKEVLDILKEELHTCMALSGCRSVAEISPDLI 348

ref|ZP_00088694.1| COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Azotobacter vinelandii]
(371 aa)

Score: 280 bits (715), Expect: 6.06492e-74
Length: 354, Idn/Pos/Gap = 162/221/3 (45%/62%/0%)

Query:  16 LAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVM  75
           LA+Y  FA+ R+    + Y A GA DE TLRDN  AF+RLR R R L D++      ++ 
Sbjct:  18 LADYEPFARERMSEQAWAYMAGGAADELTLRDNCAAFQRLRLRSRALPDLTDGHTRLELF  77

Query:  76 GIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPK 135
           G     P+++AP A Q++ HP+GELAT  A +     M +S+ A+ +LED+A      P 
Sbjct:  78 GQRFEQPILLAPVAYQKLVHPDGELATVLAASAARAGMVVSTQASVALEDIARQAQ-TPL 136

Query: 136 FFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANFA 195
           +FQLYV  DRA T  LV+RAE AG++A+ +TVD P  G R  + R  F LP  +   N  
Sbjct: 137 WFQLYVQPDRAFTRELVQRAEAAGYQALVVTVDAPVSGLRNREQRAGFALPEGVEAVNLR 196

Query: 196 DMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQRAL 255
            M+         G S L  +   L+ A+  W ++AWL+S+TRLP+L+KGV+  EDA+RAL
Sbjct: 197 GMRALPPTIARIGDSPL--FGGPLLAAAPTWRELAWLRSLTRLPLLVKGVMHPEDARRAL 254

Query: 256 QYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALALGA 315
             G DGI +SNHG R LD   ATI+ LEE+A  V GR+P+ +D G+RRGTDV+KALALGA
Sbjct: 255 AEGIDGIIVSNHGGRTLDTQPATIEVLEEIAGVVEGRLPLLLDGGIRRGTDVLKALALGA 314

Query: 316 DAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLVVR 369
            AVL+GR  V+ LA  G  GV   L LL+ E ++AM L GC+ ++DI  +L+ R
Sbjct: 315 SAVLVGRSYVFALAAAGAPGVCHALQLLRAELEVAMALTGCRTLADIGPELLWR 368

dbj|BAB31343.1| unnamed protein product [Mus musculus]
(353 aa)

Score: 280 bits (715), Expect: 6.16697e-74
Length: 354, Idn/Pos/Gap = 148/221/9 (41%/62%/2%)

Query:  14 LNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQ  73
           L LA++   A+ +L    + +    ADD  T  DN  AFRR+R RPR L DVS++D    
Sbjct:   4 LCLADFKAQAQKQLSKTSWDFIEGEADDGITYNDNLAAFRRIRLRPRYLRDVSKIDTRTT  63

Query:  74 VMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGL 133
           + G +++ P+ ++PTA   +A  +GE +TA+A  +      +SS+A+ ++ED+ A  PG 
Sbjct:  64 IQGQEINAPICISPTAFHSIAWADGEKSTAKAAQKANICYVISSYASYTVEDIVAAAPGG 123

Query: 134 PKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLAN 193
             +FQLYV  D  I +++V+R E  GF+A+ +TVD P LG R  + R+   L  ++ L +
Sbjct: 124 LHWFQLYVQPDWDINKQMVQRIEALGFKALVVTVDAPVLGNRRGNKRSLLDLEANIKLKD 183

Query: 194 FADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQR 253
                       G   SGL + + S+  +S  WND+  L+S+TRLPI+LKG++T EDA+ 
Sbjct: 184 LR--------SPGESKSGLPTPL-SMPSSSSCWNDLPLLQSMTRLPIILKGILTKEDAEL 234

Query: 254 ALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALAL 313
           A+++   GI +SNHG RQLD V A+ID L +V  +V G+I V++D GVR G DV+KALAL
Sbjct: 235 AVKHNIRGIIVSNHGGRQLDEVPASIDALRKVVAAVNGKIEVYMDGGVRTGNDVLKALAL 294

Query: 314 GADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLV 367
           GA  + +GRPI+WGLA  GE+GV  +L +LK+E    M L GC+ V++I  DL+
Sbjct: 295 GARCIFLGRPIIWGLACKGEDGVKEVLDILKEELHTCMALSGCRSVAEISPDLI 348

gb|EAA56072.1| hypothetical protein MG01723.4 [Magnaporthe grisea 70-15]
ref|XP_363797.1| hypothetical protein MG01723.4 [Magnaporthe grisea 70-15]
(494 aa)

Score: 280 bits (715), Expect: 6.64791e-74
Length: 362, Idn/Pos/Gap = 141/220/16 (38%/60%/4%)

Query:  12 QPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDIT  71
           Q  NL ++   A+  +    +GYY+S ADDE T R+N  AF R+ FRP+VL+DV  VD++
Sbjct: 107 QCYNLLDFEAVARRVMKKTAWGYYSSAADDEITFRENHSAFHRIWFRPKVLVDVENVDVS 166

Query:  72 KQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVA-AHV 130
             ++G   + P  V  TA+ ++ +PEGE+   +A  +   +  + + A+ + +++  A V
Sbjct: 167 TTMLGTKTALPFYVTATALGKLGNPEGEVCLTKAAGKHNVIQMIPTLASCAFDEIMDAAV 226

Query: 131 PGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLS 190
           PG  ++ QLYV KDR +T+R+V+ AE+ G + + +TVD PQLGRRE D+R++F+ P    
Sbjct: 227 PGQVQWLQLYVNKDREVTKRIVQYAEKRGCKGLFITVDAPQLGRREKDMRSKFEDPG--- 283

Query: 191 LANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAED 250
                      Q +    + G A  ++S ID +L+W D+ W +SIT++PI+LKGV   ED
Sbjct: 284 -------TSVQQGQTTDNSQGAARAISSFIDPALSWKDLPWFRSITKMPIVLKGVQRVED 336

Query: 251 AQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRG-----RIPVFIDSGVRRGT 305
             +A+  G DG+ +SNHG RQL+   + I+ L E    +R      +I V++D GVRRGT
Sbjct: 337 VLKAVDAGMDGVILSNHGGRQLEFARSGIEILAETMPVLRSMGLQDKIEVYLDGGVRRGT 396

Query: 306 DVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRD 365
           D++KAL LGA  V IGRP ++ ++  G +GV R + LLKDE ++ M+L GC  +  +   
Sbjct: 397 DIIKALCLGAKGVGIGRPFLYAMSAYGVQGVDRAMQLLKDELEMNMRLIGCTSIDQLSPS 456

Query: 366 LV 367
           LV
Sbjct: 457 LV 458

emb|CAD65663.1| lactate oxidase [Lactobacillus plantarum WCFS1]
ref|NP_786785.1| lactate oxidase [Lactobacillus plantarum WCFS1]
(366 aa)

Score: 274 bits (701), Expect: 2.74682e-72
Length: 357, Idn/Pos/Gap = 151/218/10 (42%/61%/2%)

Query:  14 LNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQ  73
           LNL      AK  +P+  +GY + G++DE TL+ N  AF  ++  PR L D+ +     Q
Sbjct:  19 LNLPSLEAAAKKIIPSGGFGYISGGSEDEWTLKQNTMAFNHVQIVPRALTDMEQPSTQTQ  78

Query:  74 VMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGL 133
             GIDL  P+M+AP A Q +AH  GE ATA  +A++G +M  S++++TS+ D AA   G 
Sbjct:  79 AFGIDLKTPIMMAPAAAQGLAHARGEAATAEGMAQVGALMAQSTYSSTSIADTAAAGKGA 138

Query: 134 PKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLP-PHLSLA 192
           P+FFQLY+ KD    + L+  A +AG +AI LTVD    G READI N FQ P P  +L 
Sbjct: 139 PQFFQLYMSKDWDFNQSLLDEAVKAGAKAIILTVDATVDGYREADIINNFQFPIPMANLT 198

Query: 193 NFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQ 252
            F++         G G   +  Y A+     ++  D+  +   T LP+++KG+ + EDA 
Sbjct: 199 KFSE-------GDGKGKGIMEIYAAAA--QKISPADVRRITEYTNLPVIVKGIQSPEDAL 249

Query: 253 RALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALA 312
            A+  GA GI++SNHG RQL+G  A+ D L E+AQ+V GR+P+  DSGVRRG+ V KALA
Sbjct: 250 LAIGAGAQGIYVSNHGGRQLNGGPASFDVLHEIAQAVNGRVPIIFDSGVRRGSHVFKALA 309

Query: 313 LGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLVVR 369
            GAD V + RPI++GLA+ G +GV  ++S L DE  + MQL G + + D++R  ++R
Sbjct: 310 NGADLVALARPIIYGLALGGAQGVASVVSHLNDELLIDMQLAGTKTIEDVKRAKLLR 366

emb|CAC51461.1| NAD-independent L-lactate dehydrogenase [Lactobacillus plantarum]
(366 aa)

Score: 272 bits (695), Expect: 1.34067e-71
Length: 357, Idn/Pos/Gap = 150/217/10 (42%/60%/2%)

Query:  14 LNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQ  73
           LNL      AK  +P+  +GY + G++DE TL+ N  AF  ++  PR L D+ +     Q
Sbjct:  19 LNLPSLEAAAKKIIPSGGFGYISGGSEDEWTLKQNTMAFNHVQIVPRALTDMEQPSTQTQ  78

Query:  74 VMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGL 133
             GIDL  P+M+AP A Q +AH  GE ATA  +A++G +M  S++++TS+ D AA   G 
Sbjct:  79 AFGIDLKTPIMMAPAAAQGLAHARGEAATAEGMAQVGALMAQSTYSSTSIADTAAAGKGA 138

Query: 134 PKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLP-PHLSLA 192
           P+FFQLY+ KD    + L+  A +AG +AI LTVD    G RE DI N FQ P P  +L 
Sbjct: 139 PQFFQLYMSKDWDFNQSLLDEAVKAGAKAIILTVDATVDGYREDDIINNFQFPIPMANLT 198

Query: 193 NFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQ 252
            F++         G G   +  Y A+     ++  D+  +   T LP+++KG+ + EDA 
Sbjct: 199 KFSE-------GDGKGKGIMEIYAAAA--QKISPADVRRITEYTNLPVIVKGIQSPEDAL 249

Query: 253 RALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALA 312
            A+  GA GI++SNHG RQL+G  A+ D L E+AQ+V GR+P+  DSGVRRG+ V KALA
Sbjct: 250 LAIGAGAQGIYVSNHGGRQLNGGPASFDVLHEIAQAVNGRVPIIFDSGVRRGSHVFKALA 309

Query: 313 LGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLVVR 369
            GAD V + RPI++GLA+ G +GV  ++S L DE  + MQL G + + D++R  ++R
Sbjct: 310 NGADLVALARPIIYGLALGGAQGVASVVSHLNDELLIDMQLAGTKTIEDVKRAKLLR 366

ref|NP_105534.1| glycolate oxidase, (S)-2-hydroxy-acid oxidase (EC 1.1.3.15), peroxisomal [Mesorhizobium loti MAFF303099]
dbj|BAB51320.1| glycolate oxidase (S)-2-hydroxy-acid oxidase, peroxisomal [Mesorhizobium loti MAFF303099]
(352 aa)

Score: 271 bits (693), Expect: 2.4447e-71
Length: 357, Idn/Pos/Gap = 156/215/12 (43%/60%/3%)

Query:  11 TQPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDI  70
           T+ L LA++   A+  LP  VY + A GA DE T RDNE AF R+R R RVL DV+R+D 
Sbjct:   7 TRFLGLADFEPAAREVLPHAVYEFIAGGAGDEITKRDNEAAFDRIRLRQRVLRDVTRLDT  66

Query:  71 TKQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHV 130
              + G  L+ P+++AP A QR+AHPEGE+ATAR       V  L + AT ++ED  A  
Sbjct:  67 AITLFGQRLTHPIILAPIAYQRLAHPEGEVATARGAGVAEAVFILGTTATAAIEDCVAES 126

Query: 131 PGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLS 190
              P +F LY   DR     LV R    G +AI++TVD P  G R    R  F++P  L+
Sbjct: 127 QS-PVWFLLYWQSDRGFNGELVSRMAALGAKAISVTVDLPTPGDRRRQFRAGFKIPDSLA 185

Query: 191 LANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAED 250
              F D        G A    + +           W DIAWL+S+T LP++LKG++  +D
Sbjct: 186 TPYFKDRNTGVLKVGTAQKRAMPT-----------WADIAWLRSLTTLPLILKGILDPDD 234

Query: 251 AQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKA 310
           A++A+  GAD I +SNHG+R LD + A ID L  +A+ V GRIP+ +D GVRRGTDV+KA
Sbjct: 235 AEQAIGTGADAIVVSNHGSRNLDTLPAAIDALPAIAERVAGRIPIILDGGVRRGTDVLKA 294

Query: 311 LALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLV 367
           +ALGA AV+IGRP V+ LA  G EGV   ++LL+ +F++AM L G  ++ +I R ++
Sbjct: 295 IALGASAVMIGRPYVYALATAGAEGVAHCVNLLRRDFEMAMALTGRARLGEIDRSVI 351

ref|XP_613535.1| PREDICTED: similar to hydroxyacid oxidase 1, partial [Bos taurus]
(286 aa)

Score: 269 bits (687), Expect: 1.28627e-70
Length: 265, Idn/Pos/Gap = 133/188/3 (50%/70%/1%)

Query:  16 LAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVM  75
           +++Y   AK+ L   +Y YY SGA+D++TL DN  AF R +  PR+L +++ +D++  V+
Sbjct:   8 ISDYEQHAKSVLQKSIYDYYKSGANDQETLADNIAAFSRWKLYPRMLRNIAEIDLSTSVL  67

Query:  76 GIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPK 135
           G  +S P+ V  TAMQ MAH +GELAT RA   +GT M LSSWAT+S+E+VA   P   +
Sbjct:  68 GQKVSMPICVGATAMQCMAHVDGELATVRACRSLGTGMMLSSWATSSIEEVAEAGPEAIR 127

Query: 136 FFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANFA 195
           + QLY+YKDR +T++LVRRAER G++AI +TVDTP LG R  D+RN+F++PP L + NF 
Sbjct: 128 WLQLYIYKDREVTKQLVRRAERMGYKAIFVTVDTPYLGNRFDDVRNRFKMPPQLRMKNF- 186

Query: 196 DMKD--FAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQR 253
           +  D  F+  +     SGLA+YVA  ID S++W DI WL+ +T LPI+ KG++  +DA+ 
Sbjct: 187 ETNDLAFSPKENFGDKSGLAAYVAKAIDPSISWEDIKWLRRLTSLPIVAKGILRGDDAKA 246

Query: 254 ALQYGADGIWISNHGARQLDGVTAT 278
           A+++G DGI +SNHGARQLDGV AT
Sbjct: 247 AVKHGLDGILVSNHGARQLDGVPAT 271

ref|XP_328978.1| hypothetical protein [Neurospora crassa]
gb|EAA32664.1| hypothetical protein [Neurospora crassa]
(501 aa)

Score: 268 bits (685), Expect: 2.326e-70
Length: 385, Idn/Pos/Gap = 148/224/36 (38%/58%/9%)

Query:   1 MVEKPAVNPATQ---------PL-----NLAEYHLFAKARLPAMVYGYYASGADDEQTLR  46
           + EK  V+P  Q         PL     NL ++   AK  +    + YY+S ADDE TLR
Sbjct:  86 VTEKAEVDPEEQARLKRIEEMPLLEQCYNLLDFEAVAKRVMKKNAWAYYSSAADDEITLR 145

Query:  47 DNEEAFRRLRFRPRVLIDVSRVDITKQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAV 106
           +N  AF R+ FRP+VL+DV +VD +  ++G  +  P  V  TA+ ++ H EGE+   RA 
Sbjct: 146 ENHAAFHRIWFRPKVLVDVEKVDFSTTMLGTKVDIPFYVTATALGKLGHVEGEVLLTRAA 205

Query: 107 ARIGTVMGLSSWATTSLEDVAAHVPG-LPKFFQLYVYKDRAITERLVRRAERAGFRAIAL 165
            +   V  + + A+ + +++     G   ++ QLYV KDRAITER+++ AE+ G +A+ +
Sbjct: 206 KKHNVVQMIPTLASCAFDEIMDAAEGDQVQWLQLYVNKDRAITERIIKHAEKRGCKALFI 265

Query: 166 TVDTPQLGRREADIRNQFQLPPHLSLANFADMKDFAQVKGGAGAS---GLASYVASLIDA 222
           TVD PQLGRRE D+R +F               D + V+ G   +   G A  ++S ID 
Sbjct: 266 TVDAPQLGRREKDMRVKF-------------TDDGSNVQKGHETNRNEGAARAISSFIDP 312

Query: 223 SLNWNDIAWLKSITRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCL 282
           +L+W DI W +S+T++PI+LKGV   ED  +A++ G  G+ +SNHG RQL+   + I+ L
Sbjct: 313 ALSWKDIPWFQSVTKMPIILKGVQRVEDVIKAVEAGVQGVVLSNHGGRQLEFARSGIEVL 372

Query: 283 EEVAQSVR-----GRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVY 337
            E    +R      +I V+ID G+RR TD++KAL LGA  V IGRP ++ ++  G +GV 
Sbjct: 373 AETMPVLRELGLEDKIEVYIDGGIRRATDILKALCLGAKGVGIGRPFLYAMSAYGFDGVD 432

Query: 338 RLLSLLKDEFKLAMQLCGCQKVSDI 362
           R + LLKDE ++ M+L G  K+ D+
Sbjct: 433 RAMQLLKDEMEMNMRLIGATKIEDL 457

gb|AAT08654.1| glycolate oxidase [Hyacinthus orientalis]
(253 aa)

Score: 266 bits (681), Expect: 5.92185e-70
Length: 212, Idn/Pos/Gap = 134/169/3 (63%/79%/1%)

Query:  15 NLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQV  74
           N++EY   AK +LP MVY YYASGA+D+ +LR+N EAF R+ FRPR+LIDVSR+D+T  V
Sbjct:  17 NVSEYEEIAKKKLPKMVYDYYASGAEDQWSLRENIEAFSRILFRPRILIDVSRIDMTTTV  76

Query:  75 MGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLP 134
           +G ++S P+M+APTAMQ+MAHPEGE ATARA +  GT+M LSSWAT+S+E+VA+  PG+ 
Sbjct:  77 LGFNISMPIMIAPTAMQKMAHPEGEYATARAASAAGTIMTLSSWATSSVEEVASTGPGI- 135

Query: 135 KFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANF 194
           +FFQLYVYKDR +  +LV+RAERAGF+AIALTVDTP+LGRREADI+N+F LPP L+L NF
Sbjct: 136 RFFQLYVYKDRNVVAQLVKRAERAGFKAIALTVDTPRLGRREADIKNRFTLPPFLTLKNF 195

Query: 195 ADMKDFAQVKGGAGASGLASYVASLIDASLNW 226
             +      K  A  SGLASYVA  ID SL+W
Sbjct: 196 EGLNLGKMDK--AADSGLASYVAGQIDRSLSW 225

ref|ZP_00323305.1| COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Pediococcus pentosaceus ATCC 25745]
(374 aa)

Score: 266 bits (681), Expect: 6.71138e-70
Length: 352, Idn/Pos/Gap = 141/214/8 (40%/60%/2%)

Query:  14 LNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQ  73
           LNL      A+  +P   +GY + G++DE TLR N  AF+  +  P+ L  + + ++  +
Sbjct:  24 LNLESLEERAEKIIPTGGFGYISGGSEDEWTLRQNRTAFQHRQIAPKALSGIEKPELNTE  83

Query:  74 VMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGL 133
           + GI L+ P+M+AP A Q +AH +GE  TAR +A +G +M  S++++ S+ D AA   G 
Sbjct:  84 IFGIPLNTPVMMAPAAAQGLAHSQGEKDTARGLAAVGGLMAQSTYSSVSIADTAAAGEGA 143

Query: 134 PKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLAN 193
           P+FFQLY+ KD    E L+  A++A  +AI LTVD    G READI+N+F  P  L +AN
Sbjct: 144 PQFFQLYMSKDWNFNESLLDEAKKAHVKAIILTVDATVDGYREADIKNKFAFP--LPMAN 201

Query: 194 FADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQR 253
                +     G     G+    AS    ++   D+  +   T+LP+++KG+ T EDA R
Sbjct: 202 LTKFSE-----GDGQGKGIEEIYASAAQ-NIRPEDVRRIADYTQLPVIVKGIQTPEDAIR 255

Query: 254 ALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALAL 313
           A+  GA GI++SNHG RQL+G   + D LE++A SV  ++P+  DSGVRRG+DV KALA 
Sbjct: 256 AIDAGAAGIYVSNHGGRQLNGGPGSFDVLEDIATSVNKQVPIIFDSGVRRGSDVFKALAS 315

Query: 314 GADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRD 365
           GAD V +GRP+++GLA+ G +GV  +   +  E ++ MQL G + + DI+ +
Sbjct: 316 GADIVALGRPVIYGLALGGAKGVQSVFEHIDHELEIVMQLAGTKTIDDIKNN 367

ref|NP_931544.1| hypothetical protein plu4371 [Photorhabdus luminescens subsp. laumondii TTO1]
emb|CAE16743.1| unnamed protein product [Photorhabdus luminescens subsp. laumondii TTO1]
(362 aa)

Score: 266 bits (680), Expect: 7.86432e-70
Length: 354, Idn/Pos/Gap = 144/204/11 (40%/57%/3%)

Query:  14 LNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQ  73
           +NL +    A+  +P   + Y + G+ DE TLR+N  AF   +  PR L  V   D T +
Sbjct:  17 INLYDLEEEARKLIPTPQFDYISGGSGDEWTLRENTRAFDDFQIIPRYLAGVKEPDTTTE  76

Query:  74 VMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGL 133
           ++G ++  P+ + P A   +AH   EL TAR  A  GT+    + + +SLE++A  V   
Sbjct:  77 LLGSNVDMPIFIPPIAAHGLAHTTAELGTARGAASAGTLFTAQTLSNSSLEEIA-KVSNG 135

Query: 134 PKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLAN 193
           PK+FQ+Y+ KD  I   L+RRA+  G  AI  TVD    G READ RN+F  P  L   N
Sbjct: 136 PKWFQIYLTKDMGINRELIRRAKAMGATAIVFTVDLEWSGNREADKRNKFIFPHSLPFPN 195

Query: 194 FADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQR 253
                       GA      S +  L    LN++D+ +L   + LPI++KG+ +AE+A+ 
Sbjct: 196 IP----------GAPVGATLSEITELFKRDLNFSDLEFLAKESGLPIIVKGIQSAENAKE 245

Query: 254 ALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALAL 313
            + +GA  I +SNHG RQLD V A I  L  + ++V  +IPV++D G+RRGT V KALAL
Sbjct: 246 CVNHGAAAIQVSNHGGRQLDTVPAAIASLPHIVEAVGSKIPVYLDGGIRRGTHVFKALAL 305

Query: 314 GADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLV 367
           GA AV IGRPI++ LA+ G  GV  +L+LLKDE KL+M+L GC  + DI R  +
Sbjct: 306 GAKAVAIGRPILYALALGGAPGVTSILNLLKDELKLSMKLAGCAAIKDIERKFI 359

ref|NP_267408.1| L-lactate oxidase [Lactococcus lactis subsp. lactis Il1403]
gb|AAK05350.1| L-lactate oxidase (1.13.12.) [Lactococcus lactis subsp. lactis Il1403]
pir||D86781 L-lactate oxidase [imported] - Lactococcus lactis subsp. lactis (strain IL1403)
(383 aa)

Score: 266 bits (679), Expect: 1.01858e-69
Length: 333, Idn/Pos/Gap = 145/204/10 (43%/61%/3%)

Query:  32 YGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGIDLSFPLMVAPTAMQ  91
           +GY   G++DE TL +N  AF + +  PRVL  +   D++  + GI L  P++ AP A Q
Sbjct:  54 FGYIRGGSEDEWTLNENTSAFNKKQIMPRVLRGIDSADLSTSLFGIKLKTPIIQAPVAAQ 113

Query:  92 RMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFFQLYVYKDRAITERL 151
            +AH EGE+ATA+A+A +G++  +S++ +TS+ED A   P  P+FFQLY+ KD    E L
Sbjct: 114 GLAHAEGEVATAKAMAEVGSIFSISTYGSTSVEDAAKAAPDAPQFFQLYMSKDDKFNEFL 173

Query: 152 VRRAERAGFRAIALTVDTPQLGRREADIRNQFQLP-PHLSLANFADMKDFAQVKGGAGAS 210
           +++A  AG +AI LT D+   G RE DI N FQ P P  +LA F++         G G  
Sbjct: 174 LKKAVSAGVKAIILTADSTLGGYREEDIVNHFQFPFPMPNLAAFSE-------SDGTGKG 226

Query: 211 GLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQRALQYGADGIWISNHGAR 270
               Y A+     L   DI  +K IT LP+++KGV +  DA  A+  GADGIW+SNHG R
Sbjct: 227 ISEIYAAA--KQGLVLEDIQKIKKITNLPVIVKGVQSPIDADDAINAGADGIWVSNHGGR 284

Query: 271 QLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAV 330
           QLDG  A+ID L  +A+SV  R+P+  DSGVRRG  V KALA GAD V +GRP+++GL +
Sbjct: 285 QLDGGPASIDVLPLIAKSVNHRVPIVFDSGVRRGEHVFKALAQGADVVAVGRPVLYGLNL 344

Query: 331 DGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIR 363
            G +GV  +   L  E  + MQL G + + +I+
Sbjct: 345 GGAKGVQSVFEHLNKELSITMQLAGTKNIEEIK 377

ref|ZP_00324843.1| COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Trichodesmium erythraeum IMS101]
(385 aa)

Score: 265 bits (676), Expect: 2.44612e-69
Length: 371, Idn/Pos/Gap = 146/209/21 (39%/56%/5%)

Query:  15 NLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQV  74
           N  ++   AK RLP  ++ Y    ADDEQ+ R N EA+      P VL+ V  VD++ +V
Sbjct:   8 NFQDFRKLAKRRLPGPIFDYIDGAADDEQSYRRNTEAYGECDLIPNVLVGVENVDMSVEV  67

Query:  75 MGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLP 134
           MG  L  P+  APTA+QR+ H EGE A ARA A+ GT+ G+SS AT ++E++A  +   P
Sbjct:  68 MGQKLDMPIYCAPTALQRLFHHEGERAVARAAAKYGTMFGVSSLATVTVEEIA-EITNTP 126

Query: 135 KFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANF 194
           K FQ Y +KDR + + L+ RA  A F  +ALTVDT   G RE D+R  F  PP L+L +F
Sbjct: 127 KMFQFYFHKDRGLNDALLERARAANFNVLALTVDTITGGNRERDLRTGFTSPPKLTLGSF 186

Query: 195 A------------------DMKDFAQV--KGGAGASGLASYVASLIDASLNWNDIAWLKS 234
                              DM   +    +G   A  +  Y ++++D S+NWND   L +
Sbjct: 187 MSFATHPAWAWNFLTKEKFDMPHLSGYVSQGTNLAVSVGDYFSTMLDQSMNWNDAEKLCA 246

Query: 235 ITRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIP 294
                  LKG+++ EDA+RA+  G  GI +SNHG RQLDG  +  D L E+  +V  +I 
Sbjct: 247 QWNGQFALKGIMSVEDAKRAIDIGCTGIIVSNHGGRQLDGSRSPFDQLAEICDAVGDKID 306

Query: 295 VFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLC 354
           V  + G++RGT V+KAL++GA A   GR  ++ LA  G  GV R+L  ++ E +  M+L 
Sbjct: 307 VICEGGIQRGTHVLKALSVGAKACSGGRLYLYALAAAGRAGVERVLGNMRTEIERDMKLM 366

Query: 355 GCQKVSDIRRD 365
           G  K+  + RD
Sbjct: 367 GVTKLDQLSRD 377

ref|NP_805315.1| putative glycolate oxidase [Salmonella enterica subsp. enterica serovar Typhi Ty2]
ref|NP_455877.1| putative glycolate oxidase [Salmonella enterica subsp. enterica serovar Typhi str. CT18]
emb|CAD01705.1| putative glycolate oxidase [Salmonella enterica subsp. enterica serovar Typhi]
gb|AAO69164.1| putative glycolate oxidase [Salmonella enterica subsp. enterica serovar Typhi Ty2]
pir||AH0666 probable glycolate oxidase STY1444 [imported] - Salmonella enterica subsp. enterica serovar Typhi (strain CT18)
(400 aa)

Score: 263 bits (673), Expect: 4.65048e-69
Length: 360, Idn/Pos/Gap = 146/217/12 (40%/60%/3%)

Query:  10 ATQPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVL--IDVSR  67
           A +  N+A      +AR+    +GY   GA+DE  LR N E+F +    PRVL  I++  
Sbjct:  35 AIKMTNVASLEARVQARMEKGAFGYIRGGAEDENNLRSNTESFDKKYIMPRVLQGIELKE  94

Query:  68 VDITKQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVA 127
           +D++ Q++GI L  P++ AP A Q +AH  GELATA+ +A++G++  LS++   ++E+VA
Sbjct:  95 IDLSTQLLGIPLKTPIIQAPMAAQGLAHASGELATAKGMAQVGSIFSLSTYGNKTIEEVA 154

Query: 128 AHVPGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPP 187
                 P FFQLY+ K+    E ++ +A + G +AI LTVD+P  G RE DI+N FQ P 
Sbjct: 155 NVSGKNPFFFQLYMSKNNQFNEFILAQAVKHGAKAIILTVDSPVGGYREEDIKNNFQFP- 213

Query: 188 HLSLAN---FADMKDFAQVKG-GAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLK 243
            LS AN   FA   D     G GAG S + +        +    DIA++  I+ LP+++K
Sbjct: 214 -LSFANLEMFARKNDDGSKTGKGAGISEIYAQAKQ----AFTPEDIAYVHRISGLPVIVK 268

Query: 244 GVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRR 303
           G+ + EDA+ A+Q GA GIW+SNHG RQLD   ++ D L  +A+ V  R+PV  DSGVRR
Sbjct: 269 GIQSPEDAEIAIQAGAAGIWVSNHGGRQLDSGPSSFDMLPAIAKVVNKRVPVIFDSGVRR 328

Query: 304 GTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIR 363
           G+ V KALA GAD V +GRP+++GL + G +GV  ++  L  E  + M L G + +  ++
Sbjct: 329 GSHVFKALASGADIVAVGRPVLYGLNLGGAQGVASVIEQLNKELTINMMLGGARNIEQVK 388

emb|CAB61335.1| glycolate oxidase [Laminaria digitata]
(239 aa)

Score: 263 bits (673), Expect: 4.84859e-69
Length: 229, Idn/Pos/Gap = 133/170/3 (58%/74%/1%)

Query: 142 YKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANFADM--KD 199
           YKDR IT +LV+RA  AG+ A+A+TVDTP LGRREAD+RN+F+LP HL++ NFA      
Sbjct:   1 YKDRVITAQLVKRALAAGYTALAVTVDTPVLGRREADMRNRFKLPEHLTMGNFASAGGAH  60

Query: 200 FAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSIT-RLPILLKGVVTAEDAQRALQYG 258
            +  K G   SGLA+YVASLID +L+WNDI WL++I   + I++KGV+TAEDA  A++ G
Sbjct:  61 ASGTKDGGNDSGLAAYVASLIDRTLDWNDIKWLRTICGSMKIVVKGVMTAEDASEAVRQG 120

Query: 259 ADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALALGADAV 318
            DGIWISNHGARQLD   ATI+ L EV Q+V GR  V++D G+ RGTDV KA+ALGA AV
Sbjct: 121 VDGIWISNHGARQLDTTPATIEVLPEVVQAVSGRCEVYLDGGICRGTDVFKAIALGAKAV 180

Query: 319 LIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLV 367
            IGRP++WGL   GEEGV ++L LL DE  +A+QL GC ++S   R +V
Sbjct: 181 FIGRPVLWGLGHSGEEGVSKVLKLLNDELIMALQLTGCTRISAATRAMV 229

ref|YP_216603.1| putative oxidase [Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67]
gb|AAX65522.1| putative oxidase [Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67]
(400 aa)

Score: 263 bits (672), Expect: 7.05797e-69
Length: 359, Idn/Pos/Gap = 138/216/10 (38%/60%/2%)

Query:  10 ATQPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVL--IDVSR  67
           A +  N+A      +AR+    +GY   GA+DE  LR N E+F +    PRVL  I++  
Sbjct:  35 AIKMTNVASLEARVQARMEKGAFGYIRGGAEDENNLRSNTESFDKKYIMPRVLQGIELKE  94

Query:  68 VDITKQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVA 127
           +D++ Q++GI L  P++ AP A Q +AH  GELATA+ +A++G++  LS++   ++E+VA
Sbjct:  95 IDLSTQLLGIPLKTPIIQAPMAAQGLAHASGELATAKGMAQVGSIFSLSTYGNKTIEEVA 154

Query: 128 AHVPGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPP 187
                 P FFQLY+ K+    E +  +A + G +AI LTVD+P  G RE DI+N FQ P 
Sbjct: 155 NVSGKNPFFFQLYMSKNNQFNEFIFAQAVKHGAKAIVLTVDSPVGGYREEDIKNNFQFP- 213

Query: 188 HLSLANFADMKDFAQVKGGAGASGLASYVASLI---DASLNWNDIAWLKSITRLPILLKG 244
                 FA+++ FA+       +G  + ++ +      +    DIA++  I+ LP+++KG
Sbjct: 214 ----LGFANLEMFARKNDDGSKTGKGAGISEIYAQAKQAFTPEDIAYVHRISGLPVIVKG 269

Query: 245 VVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRG 304
           + + EDA+ A+Q GA GIW+SNHG RQLD   ++ D L  +A+ V  R+PV  DSGVRRG
Sbjct: 270 IQSPEDAEIAIQAGAAGIWVSNHGGRQLDSGPSSFDMLPAIAKVVNKRVPVIFDSGVRRG 329

Query: 305 TDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIR 363
           + + KALA GAD V +GRP+++GL + G +GV  ++  L  E  + M L G + +  ++
Sbjct: 330 SHIFKALASGADIVAVGRPVLYGLNLGGAQGVASVIEQLNKELTINMMLGGARNIEQVK 388

ref|YP_150512.1| putative glycolate oxidase [Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150]
gb|AAV77200.1| putative glycolate oxidase [Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150]
(400 aa)

Score: 263 bits (671), Expect: 8.48008e-69
Length: 359, Idn/Pos/Gap = 139/217/10 (38%/60%/2%)

Query:  10 ATQPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVL--IDVSR  67
           A +  N+A      +AR+    +GY   GA+DE  LR N E+F +    PRVL  I++  
Sbjct:  35 AIKMTNVASLEARVQARMEKGAFGYIRGGAEDENNLRSNTESFDKKYIMPRVLQGIELKE  94

Query:  68 VDITKQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVA 127
           +D++ Q++GI L  P++ AP A Q +AH  GELATA+ +A++G++  LS++   ++E+VA
Sbjct:  95 IDLSTQLLGIPLKTPIIQAPMAAQGLAHASGELATAKGMAQVGSIFSLSTYGNKTIEEVA 154

Query: 128 AHVPGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPP 187
                 P FFQLY+ K+    E ++ +A + G +AI LTVD+P  G RE DI+N FQ P 
Sbjct: 155 NVSGKNPFFFQLYMSKNNQFNEFILAQAVKHGAKAIILTVDSPVGGYREEDIKNNFQFP- 213

Query: 188 HLSLANFADMKDFAQVKGGAGASGLASYVASLI---DASLNWNDIAWLKSITRLPILLKG 244
                 FA+++ FA+       +G  + ++ +      +    DIA++  I+ LP+++KG
Sbjct: 214 ----LGFANLEMFARKNDDGSKTGKGAGISEIYAQAKQAFTPEDIAYVHRISGLPVIVKG 269

Query: 245 VVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRG 304
           + + EDA+ A+Q GA GIW+SNHG RQLD   ++ D L  +A+ V  R+PV  DSGVRRG
Sbjct: 270 IQSPEDAEIAIQAGAAGIWVSNHGGRQLDSGPSSFDMLPAIAKVVNKRVPVIFDSGVRRG 329

Query: 305 TDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIR 363
           + V KALA GAD V +GRP+++GL + G +GV  ++  L  E  + M L G + +  ++
Sbjct: 330 SHVFKALASGADIVAVGRPVLYGLNLGGAQGVASVIEQLNKELTINMMLGGARNIEQVK 388

gb|AAL20538.1| putative oxidase [Salmonella typhimurium LT2]
ref|NP_460579.1| putative oxidase [Salmonella typhimurium LT2]
(400 aa)

Score: 262 bits (669), Expect: 1.58553e-68
Length: 359, Idn/Pos/Gap = 137/217/10 (38%/60%/2%)

Query:  10 ATQPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVL--IDVSR  67
           A +  N+A      +A++    +GY   GA+DE  LR N E+F +    PRVL  I++  
Sbjct:  35 AIKMTNVASLEARVQAKMEKGAFGYIRGGAEDENNLRSNTESFDKKYIMPRVLQGIELKE  94

Query:  68 VDITKQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVA 127
           +D++ Q++GI L  P++ AP A Q +AH  GELATA+ +A++G++  LS++   ++E+VA
Sbjct:  95 IDLSTQLLGIPLKTPIIQAPMAAQGLAHASGELATAKGMAQVGSIFSLSTYGNKTIEEVA 154

Query: 128 AHVPGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPP 187
                 P FFQLY+ K+    E ++ +A + G +AI LTVD+P  G RE DI+N FQ P 
Sbjct: 155 NVSGKNPFFFQLYMSKNNQFNEFILAQAVKHGAKAIILTVDSPVGGYREEDIKNNFQFP- 213

Query: 188 HLSLANFADMKDFAQVKGGAGASGLASYVASLI---DASLNWNDIAWLKSITRLPILLKG 244
                 FA+++ FA+       +G  + ++ +      +    DIA++  I+ LP+++KG
Sbjct: 214 ----LGFANLEMFARKNDDGSKTGKGAGISEIYAQAKQAFTPEDIAYVHRISGLPVIVKG 269

Query: 245 VVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRG 304
           + + EDA+ A+Q GA GIW+SNHG RQLD   ++ D L  +A+ V  R+PV  DSGVRRG
Sbjct: 270 IQSPEDAEIAIQAGAAGIWVSNHGGRQLDSGPSSFDMLPAIAKVVNKRVPVIFDSGVRRG 329

Query: 305 TDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIR 363
           + + KALA GAD V +GRP+++GL + G +GV  ++  L  E  + M L G + +  ++
Sbjct: 330 SHIFKALASGADIVAVGRPVLYGLNLGGAQGVASVIEQLNKELTINMMLGGARNIEQVK 388

ref|ZP_00361997.1| COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Polaromonas sp. JS666]
(379 aa)

Score: 261 bits (666), Expect: 3.03961e-68
Length: 370, Idn/Pos/Gap = 157/218/9 (42%/58%/2%)

Query:   5 PAVNPATQPL-NLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLI  63
           PAV P    L  LA++   A+ RL    + Y++ GA DE TLR N  A+  L   PRVL 
Sbjct:  10 PAVEPLPSGLVTLADHEAQARERLDDNAWAYFSGGAGDELTLRANRTAWDNLTLLPRVLR  69

Query:  64 DVSRVDITKQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSL 123
            ++      ++MG  L+ PL++AP A QRMAHP+GE+ATA A A  G  + LS+ A+  L
Sbjct:  70 PMAGGHTKIELMGRTLAHPLLLAPVAYQRMAHPDGEIATAHAAASQGAGLVLSTQASVPL 129

Query: 124 EDVA----AHVPGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADI 179
           E VA    A+    P +FQLY   DR  T  LV+RAE AG+ A+ LTVD P  G R+ + 
Sbjct: 130 ETVAEAFGAYAERGPLWFQLYFQHDRGFTRELVQRAEHAGYEALVLTVDAPTSGARDRER 189

Query: 180 RNQFQLPPHLSLANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLP 239
           R  F+LP  +S  N A +       G     G  +    L+  +  W D+ WL+S TRLP
Sbjct: 190 RVAFKLPAGISAVNLARLSPQPSNPG----PGYNALFDGLLAHAPTWADVEWLQSTTRLP 245

Query: 240 ILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDS 299
           ++LKGV+  EDA++A       + +SNHG R LD   AT   L  +A+++ G +P+ +D 
Sbjct: 246 VVLKGVLHPEDARQAAALRLAALIVSNHGGRTLDTAPATATILPRIAEALAGDLPLLVDG 305

Query: 300 GVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKV 359
           G+RRGTDV+KA+ALGA AVL+GRP V+GLA  G  GV  +L LL+DE ++AM LCGC  +
Sbjct: 306 GIRRGTDVLKAIALGARAVLVGRPYVYGLANAGALGVAHVLRLLRDELEIAMALCGCATL 365

Query: 360 SDIRRDLVVR 369
                +L+ +
Sbjct: 366 DQATPELLFK 375

ref|NP_107321.1| L-lactate dehydrogenase [Mesorhizobium loti MAFF303099]
dbj|BAB53107.1| L-lactate dehydrogenase [Mesorhizobium loti MAFF303099]
(378 aa)

Score: 260 bits (664), Expect: 5.27203e-68
Length: 375, Idn/Pos/Gap = 142/213/20 (37%/56%/5%)

Query:  14 LNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQ  73
           L +A+    A+ R+P M + Y  SGA  E T R NEE F++++FR RV++D+S   +   
Sbjct:   5 LTIADLKDLARRRVPKMFFDYADSGAWTESTYRANEEDFQKIKFRQRVMVDMSNRSLEST  64

Query:  74 VMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGL 133
           ++G  +S P+ +APT +  M H +GE+  A+A    G    LS+ +  S+EDVA+     
Sbjct:  65 MIGQKVSMPVALAPTGLTGMQHADGEMLAAKAAEEFGVPFTLSTMSICSIEDVASATTK- 123

Query: 134 PKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLAN 193
           P +FQLYV +D+     L+ RA+ A   A+ LT+D   LG+R  D+RN    PP ++LAN
Sbjct: 124 PFWFQLYVLRDKDFVLDLIDRAKAAKCSALVLTLDLQILGQRHKDVRNGLSAPPKMTLAN 183

Query: 194 FADMKD-------------------FAQVKGGAGASGLASYVASLIDASLNWNDIAWLKS 234
             D+                         KG    S L+S+     D  L+W D+AW+K 
Sbjct: 184 IIDLASKPRWCLGIAGTKRRTFRNIVGHAKGVGDVSSLSSWTNEQFDPQLSWKDVAWIKE 243

Query: 235 ITRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIP 294
                ++LKG++  EDA  A + GAD I +SNHG RQLDG +++I  LEE+A +V  RI 
Sbjct: 244 RWGGKLILKGILDKEDALMAAKTGADAIVVSNHGGRQLDGASSSIMVLEEIADTVGDRIE 303

Query: 295 VFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLC 354
           V +D G+R G DV+KAL LGA    IGRP ++GL   G+EGV + L +++ E  + + LC
Sbjct: 304 VHMDGGIRSGQDVLKALCLGAKGTYIGRPFLYGLGALGKEGVTKALEIIRKEMDITLALC 363

Query: 355 GCQKVSDIRRDLVVR 369
           G + V+D+ +D + R
Sbjct: 364 GKRLVTDMGKDQLRR 378

gb|EAL18966.1| hypothetical protein CNBI2270 [Cryptococcus neoformans var. neoformans B-3501A]
gb|AAW46703.1| conserved hypothetical protein [Cryptococcus neoformans var. neoformans JEC21]
ref|XP_568220.1| conserved hypothetical protein [Cryptococcus neoformans var. neoformans JEC21]
(514 aa)

Score: 258 bits (658), Expect: 2.99017e-67
Length: 413, Idn/Pos/Gap = 151/232/36 (36%/56%/8%)

Query:   2 VEKPAVNPA-TQPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPR  60
           V +  V P+  + L+L ++   A+  +    + YY+SGADDE T+R+N  A+ R+ FRPR
Sbjct: 113 VTEEFVKPSLAEILSLHDFEAVARRTMSKRGWNYYSSGADDEVTMRENHNAYHRVWFRPR 172

Query:  61 VLIDVSRVDITKQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWAT 120
           +L +V  VD + +++G   S P+ +  TA+ ++ HPEGE+   +A      +  + + A+
Sbjct: 173 ILRNVGTVDYSTEILGFKTSMPVYITATALGKLGHPEGEICLTKAAGEHNIIQMIPTLAS 232

Query: 121 TSLED-VAAHVPGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADI 179
              ++ V A +PG  +F QLYV  DR  T++++R A   G +A+ +TVD PQLGRRE D+
Sbjct: 233 CGFDEMVDAAIPGQVQFLQLYVNADRERTKKIIRHAAERGIKALFITVDAPQLGRREKDM 292

Query: 180 RNQFQLPPHLSLANFADMKDFAQVKGG---AGASGLASYVASLIDASLNWNDIAWLKSIT 236
           R +F+                 Q KGG       G A  ++S ID SLNW+D+  L    
Sbjct: 293 RTKFE-----------GTASAQQTKGGDKYQRDQGAARAISSFIDPSLNWSDLKELVDAA 341

Query: 237 R-LPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQ-------- 287
           R L ++LKGV   EDA  A + G DG+ +SNHG RQLD   + +  L  V Q        
Sbjct: 342 RGLKVILKGVQCWEDAVMAAEAGVDGVVLSNHGGRQLDFAPSPLALLPSVVQHLTAHGFM 401

Query: 288 --SVRGRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKD 345
              +R R  +F+D GVRR TDV+KA+ALGA AV IGRP+++ ++  G++GV   L +LKD
Sbjct: 402 NNPLRPRFEIFVDGGVRRATDVLKAVALGATAVGIGRPMIYAMSTYGKDGVSHALQILKD 461

Query: 346 EFKLAMQLCGCQKVSDIRRDLV-VRDAFAPY--------DVRQMLSVKMQSKL 389
           EF++ M+L G   ++D+   +V     F P         +  +ML V +++KL
Sbjct: 462 EFEMNMRLLGAPTMADVVPSMVDTSGLFGPQGSVTMYEENYERMLPVGVKAKL 514

pdb|1P5B|A Chain A, High Resolution Structure Of Reduced Active Mutant Of (S)- Mandelate Dehydrogenase
pdb|1P4C|A Chain A, High Resolution Structure Of Oxidized Active Mutant Of (S)- Mandelate Dehydrogenase
pdb|1HUV|A Chain A, Crystal Structure Of A Soluble Mutant Of The Membrane- Associated (S)-Mandelate Dehydrogenase From Pseudomonas Putida At 2.15a Resolution
(380 aa)

Score: 254 bits (650), Expect: 2.12448e-66
Length: 367, Idn/Pos/Gap = 147/219/11 (40%/59%/2%)

Query:  14 LNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQ  73
            N+ +Y   A+ RLP MVY Y   GA+DE  ++ N + F++ RF+P+ L+DVSR  +  +
Sbjct:   6 FNVEDYRKLAQKRLPKMVYDYLEGGAEDEYGVKHNRDVFQQWRFKPKRLVDVSRRSLQAE  65

Query:  74 VMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGL 133
           V+G   S PL++ PT +     P+G+LA ARA  + G    LS+ +  S+ED+A    G 
Sbjct:  66 VLGKRQSMPLLIGPTGLNGALWPKGDLALARAATKAGIPFVLSTASNMSIEDLARQCDG- 124

Query: 134 PKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLAN 193
             +FQLYV   R I + +V +A   G+  + LT D    G RE D+ N+F++PP L+L N
Sbjct: 125 DLWFQLYVIH-REIAQGMVLKALHTGYTTLVLTTDVAVNGYRERDLHNRFKIPPFLTLKN 183

Query: 194 FADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQR 253
           F  + D  ++   A     A+ ++  +DAS NW  + WL+ +    +L+KG+++AEDA R
Sbjct: 184 FEGI-DLGKMD-KANLEMQAALMSRQMDASFNWEALRWLRDLWPHKLLVKGLLSAEDADR 241

Query: 254 ALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSV-RGRIPVFIDSGVRRGTDVVKALA 312
            +  GADG+ +SNHG RQLD     I  +E +AQSV +   PV IDSG RRG+D+VKALA
Sbjct: 242 CIAEGADGVILSNHGGRQLD---CAISPMEVLAQSVAKTGKPVLIDSGFRRGSDIVKALA 298

Query: 313 LGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLVVRDAF 372
           LGA+AVL+GR  ++GLA  GE GV  +L+LLK +    +   GC  ++ +  D +  +  
Sbjct: 299 LGAEAVLLGRATLYGLAARGETGVDEVLTLLKADIDRTLAQIGCPDITSLSPDYLQNEGV 358

Query: 373 ---APYD 376
              AP D
Sbjct: 359 TNTAPVD 365

gb|AAX77931.1| unknown protein [synthetic construct]
(420 aa)

Score: 253 bits (647), Expect: 4.69352e-66
Length: 373, Idn/Pos/Gap = 135/204/24 (36%/54%/6%)

Query:  26 RLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGIDLSFPLMV  85
           R+P M   Y  +G+  +QTL+ N++ F    FR +VL D+    +  +++G +   PL+ 
Sbjct:  47 RVPKMFVDYCEAGSWQQQTLKYNQQDFGNYLFRQKVLTDIQNRSLKTKILGQEYKMPLVF 106

Query:  86 APTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFFQLYVYKDR 145
           AP  +  M H +GE+  ARA  + G    LS+ +  S E+VA H    P +FQLY+ KDR
Sbjct: 107 APIGLLGMQHADGEIHAARAAEKFGIPFTLSTMSICSTEEVAKHTTK-PFWFQLYMMKDR 165

Query: 146 AITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLAN------------ 193
                L+  A+ AG  A+ LT D   LG R ADI+N   +PP  +L N            
Sbjct: 166 KFMANLIASAKHAGCSALVLTADLQMLGDRHADIKNGLTVPPKPTLKNLINLSTKVPWCL 225

Query: 194 ---------FADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKG 244
                    F ++ + A  KGG  +  L  +     D SLNW+D+ W++      +++KG
Sbjct: 226 NMLKTSNRTFGNIVNHAANKGGFAS--LGKWTNEQFDLSLNWHDVEWVQKQWNGRMIIKG 283

Query: 245 VVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRG 304
           ++  +DA  A   GAD I +SNHG RQLDG  ++I  LEE+  +V  ++ V IDSG+R G
Sbjct: 284 IMDTQDAIMAQNTGADAIVVSNHGGRQLDGAPSSISVLEEIIDAVDRKLEVLIDSGIRTG 343

Query: 305 TDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRR 364
            D++KA ALGA A LIGRP+V+GL   GE+G YR+L +   E    M  CG   ++++ +
Sbjct: 344 QDLLKAKALGATAGLIGRPMVYGLGAYGEQGAYRVLEIFYQEMDKTMAFCGHTNINNVDK 403

Query: 365 DLVVRDAFAPYDV 377
            ++++    PYDV
Sbjct: 404 SILIKRNTYPYDV 416

ref|NP_534364.1| L-lactate dehydrogenase [Agrobacterium tumefaciens str. C58]
gb|AAL44680.1| L-lactate dehydrogenase [Agrobacterium tumefaciens str. C58]
gb|AAK89548.1| AGR_L_1949p [Agrobacterium tumefaciens str. C58]
pir||B98253 L-lactate dehydrogenase PA2382 [imported] - Agrobacterium tumefaciens (strain C58, Cereon)
pir||AB3033 L-lactate dehydrogenase lldA [imported] - Agrobacterium tumefaciens (strain C58, Dupont)
ref|NP_356763.1| hypothetical protein AGR_L_1949 [Agrobacterium tumefaciens str. C58]
(381 aa)

Score: 252 bits (644), Expect: 1.0632e-65
Length: 372, Idn/Pos/Gap = 145/212/21 (38%/56%/5%)

Query:  15 NLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQV  74
           N  ++   AK RLP  ++ Y    ADDE T R N  AF      P VL  V+ VD++  V
Sbjct:   8 NFHDFRRMAKQRLPGPIFNYIDGAADDEVTYRRNTAAFENCDLVPDVLQGVADVDMSVTV  67

Query:  75 MGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLP 134
           MG  L+ P+  +PTA+QR+ H +GE A A A  + GT+ G+SS  TTSLE+ A  + G P
Sbjct:  68 MGQKLAMPVYCSPTALQRLFHHQGEKAVAAAAGKFGTMFGVSSLGTTSLEE-ARRISGGP 126

Query: 135 KFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLA-- 192
           + +Q Y +KDR +   ++ RA+ AG   + LTVD+   G RE D R  F +P  L+L+  
Sbjct: 127 QVYQFYFHKDRGLNRDMMARAKSAGVETMMLTVDSITGGNRERDKRTGFAIPFKLNLSGI 186

Query: 193 -----------NFADMKDFA------QVKGGAGASGLASYVASLIDASLNWNDIAWLKSI 235
                      N+   + F+       +K   GA  ++ Y   ++D S+NW+D+A +   
Sbjct: 187 AQFAMKPAWGINYLTHERFSLPQLDDHIKMDGGALSISRYFTEMLDPSMNWDDVALMVRE 246

Query: 236 TRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPV 295
              P  LKG+++ +DA+RA++ G  GI +SNHG RQLDG  +  D L E+  +V  RI V
Sbjct: 247 WGGPFCLKGIMSVDDARRAVEIGCSGIVLSNHGGRQLDGSRSAFDQLAEIVDAVGDRIDV 306

Query: 296 FIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCG 355
            +D GV+RGT V+KAL+LGA AV +GR  ++ LA  G+ GV R L  ++ E +  M+L G
Sbjct: 307 MMDGGVQRGTHVLKALSLGAKAVGLGRYYLFPLAAAGQPGVERALETMRIEIERGMKLMG 366

Query: 356 CQKVSDI-RRDL 366
           C  V  + RR+L
Sbjct: 367 CTTVDQLTRRNL 378

gb|AAK81834.1| glycolate oxidase [Streptomyces lavendulae]
(372 aa)

Score: 252 bits (644), Expect: 1.25629e-65
Length: 350, Idn/Pos/Gap = 152/207/3 (43%/59%/0%)

Query:  14 LNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQ  73
           L++ +    A A LP  V+ + A G+  E +L  N  AF  +  RPR+L DVS       
Sbjct:  15 LDMEDVERAAAAALPPDVWDFIAGGSGRELSLAANRAAFDAVFVRPRILRDVSGCGAEST  74

Query:  74 VMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGL 133
           ++G  +  P+ + P A  R+  PEGELATARA    G    L++ ++  +E+V A   G 
Sbjct:  75 LLGRAVRMPVAIGPVAYHRLVCPEGELATARAAKAAGVPFTLATLSSVPVEEVTA--VGG 132

Query: 134 PKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLAN 193
             +FQLY  +D   T  LVRR E AG  AI LTVD P +GRR  D+RN F LP H+   +
Sbjct: 133 SVWFQLYWLRDTGRTLDLVRRGEDAGCEAIVLTVDVPWMGRRLRDVRNGFALPDHVRAVH 192

Query: 194 FADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQR 253
                  A  +GG GAS +A + A     SL W+++  L+  TRLPI+LKGV+  EDA+R
Sbjct: 193 LGGGASTAH-RGGDGASAVAVHTAETFSRSLTWSNVERLRECTRLPIVLKGVLAPEDARR 251

Query: 254 ALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALAL 313
           A+++G D + +SNHG RQLDG    +D L EV ++V G   + +D GVR GTDV+KALAL
Sbjct: 252 AVEHGVDAVGVSNHGGRQLDGALTAVDALPEVVEAVGGTCEILLDGGVRSGTDVLKALAL 311

Query: 314 GADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIR 363
           GA  VL+GR  VWGLA  GE+GV ++L LL  E   A+ L GC  V++ R
Sbjct: 312 GASGVLVGRAPVWGLAAGGEDGVRQVLELLAAEVTDALGLAGCAGVAEAR 361

gb|EAA64346.1| hypothetical protein AN9014.2 [Aspergillus nidulans FGSC A4]
ref|XP_413151.1| hypothetical protein AN9014.2 [Aspergillus nidulans FGSC A4]
(323 aa)

Score: 252 bits (643), Expect: 1.37705e-65
Length: 349, Idn/Pos/Gap = 144/196/57 (41%/56%/16%)

Query:  16 LAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVM  75
           +A+      +RLPA    YY  GA D  TLRDNE AF R +  PRVLI+V++VD + +++
Sbjct:  15 IADLKALGSSRLPA-TSDYYNEGAMDLITLRDNEAAFDRYKILPRVLINVAKVDTSTEIL  73

Query:  76 GIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPK 135
           G  +S P   +P A Q++AHP+GELAT+RA A  G  MGLSS++  SLEDVAA   G P 
Sbjct:  74 GTKVSLPFGFSPAASQKLAHPDGELATSRAAANFGICMGLSSYSNYSLEDVAAQGMGNPY 133

Query: 136 FFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANFA 195
             Q+ V +DR+IT +L+                     +R  +  N+  LP         
Sbjct: 134 VMQMCVLRDRSITLQLL---------------------QRAENAPNRPSLP--------- 163

Query: 196 DMKDFAQVKGGAGASGLASYVASLIDASLNW-NDIAWLKSITRLPILLKGVVTAEDAQRA 254
                                    D SL+W + I WL+  T + I LKGV +  D + A
Sbjct: 164 -------------------------DPSLDWASTIPWLREHTSMQIWLKGVCSPADVELA 198

Query: 255 LQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALALG 314
           + YG DGI ISNHG RQLDGV AT+D L   A+  +GRIP+ ID G+RRG+D+ KALALG
Sbjct: 199 IHYGVDGIVISNHGGRQLDGVPATLDSLRLCAEVAKGRIPLAIDGGIRRGSDIFKALALG 258

Query: 315 ADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIR 363
           A    +GR  +WGLA +G+EGV   + +L+ E ++ M L GCQ +S+IR
Sbjct: 259 ARYCFMGRIPIWGLAYNGQEGVELAIKILRQELRVTMALAGCQTISEIR 307

ref|NP_886520.1| L-lactate dehydrogenase [Bordetella parapertussis 12822]
emb|CAE35344.1| L-lactate dehydrogenase [Bordetella bronchiseptica RB50]
emb|CAE39673.1| L-lactate dehydrogenase [Bordetella parapertussis]
ref|NP_891514.1| L-lactate dehydrogenase [Bordetella bronchiseptica RB50]
(387 aa)

Score: 252 bits (643), Expect: 1.48444e-65
Length: 372, Idn/Pos/Gap = 142/210/20 (38%/56%/5%)

Query:  16 LAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVM  75
           + +  + A+ R+P M Y Y  SGA  E T R NE  F+R++ R RV +D+    +   + 
Sbjct:  11 IEDLRVIAQKRVPRMFYDYADSGAWTESTYRANESDFQRIKLRQRVAVDMEGRSLRTTMA  70

Query:  76 GIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPK 135
           G D   P+ +APT +  M H +GE+  ARA A  G    LS+ +  S+EDVA    G P 
Sbjct:  71 GSDAVMPVAIAPTGLTGMQHADGEILAARAAAEFGVPFTLSTMSICSIEDVA-QGSGKPF 129

Query: 136 FFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANFA 195
           +FQLYV +DR     L+ RA+ AG  A+ LT+D   LG+R  DI+N    PP  +L N  
Sbjct: 130 WFQLYVMRDREFVGDLIDRAKAAGCSALVLTLDLQILGQRHKDIKNGLSAPPKPTLRNLI 189

Query: 196 DM---------------KDFAQV----KGGAGASGLASYVASLIDASLNWNDIAWLKSIT 236
           D+               + F  +    KG    S L+S+ A   D  L+W+D+ W+K   
Sbjct: 190 DLAFKPRWCLGMLGTRRRTFGNIVGHAKGVTDLSSLSSWTAEQFDPRLSWDDVEWIKRRW 249

Query: 237 RLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVF 296
              ++LKG++ AEDA+ A + GAD + +SNHG RQLDG  ++I+ L  +A++V  RI V+
Sbjct: 250 GGKLILKGILDAEDARLAAESGADALIVSNHGGRQLDGAISSINALPAIAEAVGSRIEVW 309

Query: 297 IDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGC 356
           +D G+R G DV+KA+ALGA   +IGR  ++GL   G+ GV R L +L  E  + M LCG 
Sbjct: 310 MDGGIRSGQDVLKAVALGARGTMIGRAFLYGLGAYGQAGVTRALEILYKEMDVTMALCGH 369

Query: 357 QKVSDIRRDLVV 368
           + +S I R +++
Sbjct: 370 KHISQIDRGILM 381

ref|YP_223107.1| LldD, L-lactate dehydrogenase [Brucella abortus biovar 1 str. 9-941]
gb|AAX75746.1| LldD, L-lactate dehydrogenase [Brucella abortus biovar 1 str. 9-941]
gb|AAN34092.1| L-lactate dehydrogenase [Brucella suis 1330]
ref|NP_700087.1| L-lactate dehydrogenase [Brucella suis 1330]
(381 aa)

Score: 252 bits (643), Expect: 1.61361e-65
Length: 373, Idn/Pos/Gap = 137/212/20 (36%/56%/5%)

Query:  14 LNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQ  73
           + +A+    A+ R+P M + Y  SGA  E T R NE+ F++++ R RVL+D++   +   
Sbjct:   5 VEIADLKRLARRRVPKMFFDYADSGAWTESTYRANEDDFKKIKLRQRVLVDMTNRSLETT  64

Query:  74 VMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGL 133
           ++G  ++ P+ +APT +  M H  GE+  A+A    G    LS+ +  S+EDVA+ V   
Sbjct:  65 MIGEKVAMPVALAPTGLTGMQHANGEMLAAQAAEAFGVPFTLSTMSICSIEDVAS-VTKK 123

Query: 134 PKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLAN 193
           P +FQLYV +DR   + L+ RA+ AG  A+ LT+D   LG+R  DIRN    PP  +  +
Sbjct: 124 PFWFQLYVMRDRDFVKNLIGRAKAAGCSALVLTLDLQILGQRHKDIRNGLSAPPKFTPKH 183

Query: 194 FADM---------------KDFAQVKGGA----GASGLASYVASLIDASLNWNDIAWLKS 234
              M               + F  + G A      S L+S+ A   D  LNW+D+ W+K 
Sbjct: 184 IWQMATCPAWCLGMLGTQRRTFRNIAGHAKNVTDLSSLSSWTAEQFDPQLNWSDVEWIKE 243

Query: 235 ITRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIP 294
                ++LKG++  EDA+ A + GAD I +SNHG RQLDG  ++I  L+ + ++V  RI 
Sbjct: 244 QWGGKLILKGILDVEDAKMAAKSGADAIIVSNHGGRQLDGAPSSISMLQPIVEAVGDRIE 303

Query: 295 VFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLC 354
           V +D G+R G DV+KA ALGA  V IGRP ++GL   G+EGV   L +++ E  + M LC
Sbjct: 304 VHVDGGIRSGQDVLKARALGAQGVYIGRPFLYGLGAMGKEGVTLALEIIRKEMDITMALC 363

Query: 355 GCQKVSDIRRDLV 367
           G + +++I + ++
Sbjct: 364 GKRDINEIDKSII 376

ref|NP_103982.1| glycolate oxidase [Mesorhizobium loti MAFF303099]
dbj|BAB49768.1| glycolate oxidase [Mesorhizobium loti MAFF303099]
(381 aa)

Score: 251 bits (642), Expect: 1.85952e-65
Length: 372, Idn/Pos/Gap = 141/206/26 (37%/55%/6%)

Query:  15 NLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQV  74
           N +++   A+ RLP  ++ Y    ADDE T R N E+F      P VL  V+ +D++  V
Sbjct:   8 NFSDFRRMAQRRLPGPIFDYIDGAADDEVTYRRNTESFETCDLVPNVLRGVNEIDMSVTV  67

Query:  75 MGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLP 134
           MG  L+ P   +PTA+QR+ H +GE A A+A A+ GT+ G+SS  T SLE+ A  +   P
Sbjct:  68 MGQKLAMPFYCSPTALQRLFHHQGERAVAKAAAKYGTMFGVSSLGTVSLEE-ARSISSSP 126

Query: 135 KFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANF 194
           + +Q Y ++DR +   +++RA++ G   + LTVD+   G RE D R  F +P  L   N 
Sbjct: 127 QVYQFYFHRDRGLNRAMMQRAKQVGVEVMMLTVDSITGGNRERDKRTGFAIPFKL---NL 183

Query: 195 ADMKDFA----------------------QVKGGAGASGLASYVASLIDASLNWNDIAWL 232
           A M  FA                       V  G G   ++ Y   ++D S+ W+D+A +
Sbjct: 184 AGMAQFALKPAWAINYFTHEGFKLPQLDEHVDMGGGTMSISRYFTEMLDPSMTWDDVAEM 243

Query: 233 KSITRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGR 292
                 P  LKG+++ EDA+RA + G  GI +SNHG RQLDG  A  D L E+ ++V  R
Sbjct: 244 VRQWSGPFCLKGIMSVEDAKRAAEIGCSGIVLSNHGGRQLDGSRAAFDQLAEIVEAVGDR 303

Query: 293 IPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQ 352
           I V +D GV+RGT V+KAL+LGA AV IGR  ++ LA  G+ GV R L  ++ E +  M+
Sbjct: 304 IDVIMDGGVQRGTHVLKALSLGAKAVGIGRYYLFPLAAAGQPGVERALEQMRVEIERGMK 363

Query: 353 LCGCQKVSDIRR 364
           L GC  +  + R
Sbjct: 364 LMGCSSIGQLSR 375

gb|EAL03561.1| hypothetical protein CaO19.12467 [Candida albicans SC5314]
gb|EAL03437.1| hypothetical protein CaO19.5000 [Candida albicans SC5314]
(560 aa)

Score: 251 bits (642), Expect: 1.90665e-65
Length: 381, Idn/Pos/Gap = 134/218/27 (35%/57%/7%)

Query:  11 TQPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDI  70
           +Q  NL ++   A+  +  + + YY+S AD E T R N  +++R+ F+PRV+IDV+ +D 
Sbjct: 174 SQIYNLYDFEFVARHTMDPIGWAYYSSSADGEATFRLNTGSYQRIFFKPRVMIDVTEIDT 233

Query:  71 TKQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHV 130
           +  ++G  +S P  +  TA+ ++ HP+GE    R   +   +  + + A+ S +++    
Sbjct: 234 STTMLGTKVSVPFYITATALGKLGHPDGEKVLTRGAQKHDLIQMIPTLASCSFDEIVDEA 293

Query: 131 -PGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHL 189
            P   ++FQLYV  DR IT+++V+ AE  G + + +TVD PQLGRRE D++ +       
Sbjct: 294 KPNQTQWFQLYVNSDREITKKIVQHAEARGMKGLFITVDAPQLGRREKDMKTK------- 346

Query: 190 SLANFADMKDFAQVKG----GAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGV 245
                  + D + V+G       + G A  ++S ID SL+W D+ W KSIT++PI+LKGV
Sbjct: 347 ------SIVDLSFVQGEDDEADRSQGSARAISSFIDTSLSWKDLKWFKSITKMPIILKGV 400

Query: 246 VTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGR-----IPVFIDSG 300
              EDA  A ++G  G+ +SNHG RQL+     I+ L E+   +R +       V+ID G
Sbjct: 401 QRVEDAIIAAEHGCAGVVLSNHGGRQLEFSPPPIEVLAELMPILREKGLADNFEVYIDGG 460

Query: 301 VRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVS 360
           VRR TD++KA+ LGA  V IGRP ++ ++  G+ GV + + LLKDE  + M+L G  K+ 
Sbjct: 461 VRRATDILKAVCLGAKGVGIGRPFLYAMSGYGDAGVNKAIQLLKDEMIMNMRLLGVNKLE 520

Query: 361 DIRRDLV----VRDAFAPYDV 377
           ++    V    ++  + P DV
Sbjct: 521 ELNELFVDTKYMQTRYVPDDV 541

gb|EAA69176.1| hypothetical protein FG01812.1 [Gibberella zeae PH-1]
ref|XP_381988.1| hypothetical protein FG01812.1 [Gibberella zeae PH-1]
(500 aa)

Score: 251 bits (642), Expect: 1.92263e-65
Length: 366, Idn/Pos/Gap = 143/216/13 (39%/59%/3%)

Query:   7 VNPATQPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVS  66
           + P    L+  ++   A+  L A  + +Y+S A D  T   N+E  RRL  RPR+L +VS
Sbjct: 122 IPPLDAILSARDFEEAARDHLSAKTWAFYSSAATDLITHGKNKELVRRLMIRPRILRNVS 181

Query:  67 RVDITKQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDV 126
            V+    ++G+D + P  ++P AM R+AHP+GELA +RA A  G +  +SS A+ SL+ +
Sbjct: 182 NVNFKTNILGLDSNAPFFISPAAMARLAHPDGELALSRAAANEGIIQCISSNASFSLKSI 241

Query: 127 AAHVP-GLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQL 185
              VP   P FFQLYV  D + T  L+R     G +AI +TVD P  G+READ R   + 
Sbjct: 242 VKAVPSSQPFFFQLYVNSDHSKTVELLRMVADLGVKAIFVTVDAPVPGKREADERAAQEQ 301

Query: 186 PPHLSLANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSIT-RLPILLKG 244
               +++     KD    K G   SG    +A  ID +L+W+D+ W++  +  LPI+LKG
Sbjct: 302 TVKSAISGGESSKD----KKG---SGFGRLMAQYIDKTLSWDDLGWIREASGGLPIVLKG 354

Query: 245 VVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQS---VRGRIPVFIDSGV 301
           V TAED  +A +YG +G+ +SNHG R LDG  A+I  L E+ ++   +  +I ++ID G 
Sbjct: 355 VQTAEDVIQAAEYGVEGVLLSNHGGRSLDGAQASILVLLELRKNCPEIFDKIEIYIDGGF 414

Query: 302 RRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSD 361
            RG+D++KA+ LGA AV IGRP ++ L + G++G   L  +LKDE + +M+LCG   +S 
Sbjct: 415 ERGSDILKAICLGATAVGIGRPFLYSL-IHGQDGAEHLCHILKDELETSMRLCGITSLSQ 473

Query: 362 IRRDLV 367
            +  L+
Sbjct: 474 AKPSLI 479

gb|EAA07214.2| ENSANGP00000024226 [Anopheles gambiae str. PEST]
ref|XP_311494.2| ENSANGP00000024226 [Anopheles gambiae str. PEST]
(370 aa)

Score: 251 bits (641), Expect: 2.51103e-65
Length: 353, Idn/Pos/Gap = 150/206/6 (42%/58%/1%)

Query:  15 NLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVL--IDVSRVDITK  72
           ++A+Y       +   V  Y   GA  E+T+  N  AF RL  RPR L  I  SR  +  
Sbjct:   4 SVADYERRVCETVDGTVVDYCRGGAASERTVAQNRAAFDRLIIRPRCLQRIGGSR-SLAV  62

Query:  73 QVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPG 132
              G+    P+ +AP A+Q +AHPEGE A ARA    G    LS  ++ S+E++A  VP 
Sbjct:  63 TSFGVSYRMPIGIAPVALQCLAHPEGEKAMARAARTHGVPFVLSVLSSVSIEELAEAVPR 122

Query: 133 LPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLA 192
            PK+FQLY++KDR +TE LVRRAE+A FRA+ ++VDTP  G   ++ RN   LP  ++ A
Sbjct: 123 APKWFQLYIFKDRELTECLVRRAEKARFRALVVSVDTPAPGLSRSERRNPLTLPAKVTCA 182

Query: 193 NFADMKDFAQVKGGAGASGLAS---YVASLIDASLNWNDIAWLKSITRLPILLKGVVTAE 249
           NF    + A   G A     AS   YV S +D SL W+ I WL SIT LP+++KG++   
Sbjct: 183 NFVPGGNGANGNGKASQPCSASVLDYVRSQLDPSLGWDAIQWLMSITTLPVIVKGILNRA 242

Query: 250 DAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVK 309
           DA  A   G  G+ +SN G RQLD   A I+ L E+  +V  R+ V +DSGV +GTD  K
Sbjct: 243 DALIAADIGVHGLIVSNSGGRQLDYAPAAIEVLPEIVHAVGNRLEVMLDSGVSQGTDTFK 302

Query: 310 ALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDI 362
           ALA+GA  V +GR  V+GLAV+G+ GV  +L +LK E +  M   GC  ++D+
Sbjct: 303 ALAIGARMVFVGRAAVYGLAVNGQRGVEEVLDILKTELESTMLNAGCGTLADV 355

ref|NP_541355.1| L-LACTATE DEHYDROGENASE (CYTOCHROME) [Brucella melitensis 16M]
gb|AAL53619.1| L-LACTATE DEHYDROGENASE (CYTOCHROME) [Brucella melitensis 16M]
pir||AH3556 l-lactate dehydrogenase (cytochrome) (EC 1.1.2.3) [imported] - Brucella melitensis (strain 16M)
(382 aa)

Score: 251 bits (641), Expect: 2.84581e-65
Length: 373, Idn/Pos/Gap = 137/211/20 (36%/56%/5%)

Query:  14 LNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQ  73
           + +A+    A+ R+P M + Y  SGA  E T R NE+ F++++ R RVL+D++   +   
Sbjct:   6 VEIADLKRLARRRVPKMFFDYADSGAWTESTYRANEDDFKKIKLRQRVLVDMTNRSLETT  65

Query:  74 VMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGL 133
           ++G  ++ P+ +APT +  M H  GE+  A+A    G    LS+ +  S+EDVA+ V   
Sbjct:  66 MIGEKVAMPVALAPTGLTGMQHANGEMLAAQAAEAFGVPFTLSTMSICSIEDVAS-VTKK 124

Query: 134 PKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLAN 193
           P +FQLYV +DR   + L+ RA+ AG  A+ LT+D   LG+R  DIRN    PP  +  +
Sbjct: 125 PFWFQLYVMRDRDFVKNLIGRAKAAGCSALVLTLDLQILGQRHKDIRNGLSAPPKFTPKH 184

Query: 194 FADM---------------KDFAQVKGGA----GASGLASYVASLIDASLNWNDIAWLKS 234
              M               + F  + G A      S L+S+ A   D  LNW+D+ W+K 
Sbjct: 185 IWQMATCPAWCLGMLGTQRRTFRNIAGYAKNVTDLSSLSSWTAEQFDPQLNWSDVEWIKE 244

Query: 235 ITRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIP 294
                ++LKG++  EDA+ A + GAD I +SNHG RQLDG  ++I  L+ + ++V  RI 
Sbjct: 245 QWGGKLILKGILDVEDAKMAAKSGADAIIVSNHGGRQLDGAPSSISMLQPIVEAVGDRIE 304

Query: 295 VFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLC 354
           V +D G+R G DV+KA ALGA  V IGRP ++GL   G EGV   L +++ E  + M LC
Sbjct: 305 VHVDGGIRSGQDVLKARALGAQGVYIGRPFLYGLGAMGNEGVTLALEIIRKEMDITMALC 364

Query: 355 GCQKVSDIRRDLV 367
           G + +++I + ++
Sbjct: 365 GKRDINEIDKSII 377

emb|CAE44813.1| L-lactate dehydrogenase [Bordetella pertussis Tohama I]
ref|NP_879338.1| L-lactate dehydrogenase [Bordetella pertussis Tohama I]
(387 aa)

Score: 251 bits (640), Expect: 3.22523e-65
Length: 372, Idn/Pos/Gap = 141/209/20 (37%/56%/5%)

Query:  16 LAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVM  75
           + +  + A+ R+P M Y Y  SGA  E T R NE  F+R++ R RV +D+    +   + 
Sbjct:  11 IEDLRVIAQKRVPRMFYDYADSGAWTESTYRANESDFQRIKLRQRVAVDMEGRSLRTTMA  70

Query:  76 GIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPK 135
           G D   P+ +APT +  M H +GE+  ARA A  G    LS+ +  S+EDVA    G P 
Sbjct:  71 GSDAVMPVAIAPTGLTGMQHADGEILAARAAAEFGVPFTLSTMSICSIEDVA-QGSGKPF 129

Query: 136 FFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANFA 195
           +FQLYV +DR     L+ RA+ AG  A+ LT+D   LG+R  DI+N    PP  +L N  
Sbjct: 130 WFQLYVMRDREFVGNLIDRAKAAGCSALVLTLDLQILGQRHKDIKNGLSAPPRPTLRNLI 189

Query: 196 DM---------------KDFAQV----KGGAGASGLASYVASLIDASLNWNDIAWLKSIT 236
           D+               + F  +    KG    S L+S+ A   D  L+W+D+ W+K   
Sbjct: 190 DLAFKPRWCLGMLGTRRRTFGNIVGHAKGVTDLSSLSSWTAEQFDPRLSWDDVEWIKRRW 249

Query: 237 RLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVF 296
              ++LKG++ AEDA+ A + GAD + +SNHG RQLDG  ++I  L  +A++V  RI V+
Sbjct: 250 GGKLILKGILDAEDARLAAESGADALIVSNHGGRQLDGAVSSISALPAIAEAVGSRIEVW 309

Query: 297 IDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGC 356
           +D G+R G DV+KA+ALGA   +IGR  ++GL   G+ GV R L +L  E  + M LCG 
Sbjct: 310 MDGGIRSGQDVLKAVALGARGTMIGRAFLYGLGAYGQAGVTRALGILYKEMDVTMALCGH 369

Query: 357 QKVSDIRRDLVV 368
           + ++ I R +++
Sbjct: 370 KHINQIDRGILM 381

emb|CAH00282.1| unnamed protein product [Kluyveromyces lactis NRRL Y-1140]
ref|XP_453186.1| unnamed protein product [Kluyveromyces lactis]
(589 aa)

Score: 251 bits (640), Expect: 3.56488e-65
Length: 395, Idn/Pos/Gap = 144/223/36 (36%/56%/9%)

Query:  14 LNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQ  73
           +N+ ++   A   L    + YY+S ADDE T R+N  A+ R+ F+PR+L++V  VD +  
Sbjct: 202 VNIYDFEFLASQILTKQAWSYYSSAADDEVTHRENHAAYHRIFFKPRILVNVKEVDTSTT 261

Query:  74 VMGIDLSFPLMVAPTAMQRMAHP-EGELATARAVAR--IGTVMGLSSWATTSLEDVAAHV 130
           ++G  +  P  V+ TA+ ++ +P EGE   AR      +  V  +S+ A+ SL+++    
Sbjct: 262 MLGEKVGVPFYVSATALCKLGNPKEGEKDIARGCGESDVKPVQMISTLASCSLQEIVEAA 321

Query: 131 PGLPK--FFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPH 188
           P   +  +FQLYV  DR ITE L++  E+ G +AI +TVD P LG RE D + +F     
Sbjct: 322 PSKEQIQWFQLYVNSDRKITEDLIKNVEKLGLKAIFVTVDAPSLGNREKDAKVKF----- 376

Query: 189 LSLANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTA 248
            + +N A   + ++VK   GAS     ++S ID +LNW+DI   K  T+LPI++KGV   
Sbjct: 377 -TNSNGAKAMEKSKVKESKGAS---RALSSFIDPALNWDDIIEFKKKTKLPIVIKGVQCV 432

Query: 249 EDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVR-----GRIPVFIDSGVRR 303
           ED  +A + G  G+ +SNHG RQLD   A I+ L E    +R      +I +FID GVRR
Sbjct: 433 EDVLKAAEIGVAGVVLSNHGGRQLDFSRAPIEVLAETMPVLREKKLDDKIEIFIDGGVRR 492

Query: 304 GTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVS--- 360
           GTD++KAL LGA  V +GRP ++  +  G+EGV + + LLKDE +++M+L G   +    
Sbjct: 493 GTDILKALCLGAKGVGLGRPFLYSNSCYGKEGVKKAIELLKDELEMSMRLLGVTSIDQLS 552

Query: 361 --------------DIRRDLVVRDAFAPYDVRQML 381
                         ++ RD + R+ + P++  Q L
Sbjct: 553 EKYLDLSTIHGRTVNVPRDNLYREVYVPHEPTQFL 587

emb|CAB45871.1| cytochrome b2 [Kluyveromyces lactis]
(585 aa)

Score: 249 bits (636), Expect: 1.05467e-64
Length: 393, Idn/Pos/Gap = 143/222/36 (36%/56%/9%)

Query:  14 LNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQ  73
           +N+ ++   A   L    + YY+S ADDE T R+N  A+ R+ F+PR+L++V  VD +  
Sbjct: 201 VNIYDFEFLASQILTKQAWSYYSSAADDEVTHRENHAAYHRIFFKPRILVNVKEVDTSTT 260

Query:  74 VMGIDLSFPLMVAPTAMQRMAHP-EGELATARAVAR--IGTVMGLSSWATTSLEDVAAHV 130
           ++G  +  P  V+ TA+ ++ +P EGE   AR      +  V  +S+ A+ SL+++    
Sbjct: 261 MLGEKVGVPFYVSATALCKLGNPKEGEKDIARGCGESDVKPVQMISTLASCSLQEIVEAA 320

Query: 131 PGLPK--FFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPH 188
           P   +  +FQLYV  DR ITE L++  E+ G +AI +TVD P LG RE D + +F     
Sbjct: 321 PSKEQIQWFQLYVNSDRKITEDLIKNVEKLGLKAIFVTVDAPSLGNREKDAKVKF----- 375

Query: 189 LSLANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTA 248
            + +N A   + ++VK   GAS     ++S ID +LNW+DI   K  T+LPI++KGV   
Sbjct: 376 -TNSNGAKAMEKSKVKESKGAS---RALSSFIDPALNWDDIIEFKKKTKLPIVIKGVQCV 431

Query: 249 EDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVR-----GRIPVFIDSGVRR 303
           ED  +A + G  G+ +SNHG RQLD   A I+ L E    +R      +I +FID GVRR
Sbjct: 432 EDVLKAAEIGVAGVVLSNHGGRQLDFSRAPIEVLAETMPVLREKKLDDKIEIFIDGGVRR 491

Query: 304 GTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVS--- 360
           GTD++KAL LGA  V +GRP ++  +  G+EGV + + LLKDE +++M+L G   +    
Sbjct: 492 GTDILKALCLGAKGVGLGRPFLYSNSCYGKEGVKKAIELLKDELEMSMRLLGVTSIDQLS 551

Query: 361 --------------DIRRDLVVRDAFAPYDVRQ 379
                         ++ RD + R+ + P++  Q
Sbjct: 552 EKYLDLSTIHGRTVNVPRDNLYREVYVPHEPTQ 584

gb|AAB65955.2| Hypothetical protein F41E6.5 [Caenorhabditis elegans]
ref|NP_505218.2| FMN-dependent alpha-hydroxy acid dehydrogenase (5J85) [Caenorhabditis elegans]
(320 aa)

Score: 249 bits (635), Expect: 1.24621e-64
Length: 269, Idn/Pos/Gap = 128/168/3 (47%/62%/1%)

Query:  14 LNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQ  73
           L L +Y  F++  L  +   YY SGA+ E++LR N  AF  L  RPR L  V  +D +  
Sbjct:   7 LTLDDYRKFSEKNLVKLARDYYESGAEQEESLRRNISAFNNLLIRPRCLRSVENIDTSID  66

Query:  74 VM-GIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVA--AHV 130
            + G    FP+ +APTA Q+MA  +GEL+T R  A   ++M  SSW+TTS+ED+   A +
Sbjct:  67 WLNGKKSVFPVGIAPTAFQKMATLDGELSTVRGAAASNSIMICSSWSTTSVEDIGKEAKI 126

Query: 131 PGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLS 190
            G   +FQLYVYKDRAITE L+ RAE AG  A+ LTVDTP LGRR  D  N+F LP HL 
Sbjct: 127 VGATIWFQLYVYKDRAITESLIHRAEAAGVEALVLTVDTPVLGRRLKDTYNKFSLPKHLK 186

Query: 191 LANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAED 250
            ANF         KG  G SG   YV+S ID SL+WN + W+++ T LP+++KGV+  +D
Sbjct: 187 FANFESNTQAEMPKGHVGESGFMQYVSSQIDPSLDWNTLKWIRTKTNLPVIVKGVMRGDD 246

Query: 251 AQRALQYGADGIWISNHGARQLDGVTATI 279
           A  AL+ G DGI +SNHG RQ+D   AT+
Sbjct: 247 ALLALEAGVDGIIVSNHGGRQMDCTVATV 275

ref|NP_949656.1| L-lactate dehydrogenase [Rhodopseudomonas palustris CGA009]
emb|CAE29761.1| L-lactate dehydrogenase [Rhodopseudomonas palustris CGA009]
(379 aa)

Score: 249 bits (635), Expect: 1.41236e-64
Length: 359, Idn/Pos/Gap = 134/206/21 (37%/57%/5%)

Query:  24 KARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGIDLSFPL  83
           K R+P M + Y   G+  E+TLR N +  +R++FR R+L+D+S+ D+   ++G   + PL
Sbjct:  15 KRRVPKMFFDYVDHGSYAEETLRANVDDLKRIKFRQRILVDISKRDLATTILGDTYAMPL  74

Query:  84 MVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFFQLYVYK 143
           ++AP     M H +GE+   RA    G    LS+ +  S+EDVAA+V   P +FQLYV +
Sbjct:  75 ILAPVGSTGMQHADGEIHACRAAQAAGIPYTLSTMSICSIEDVAANVEK-PFWFQLYVMR 133

Query: 144 DRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHL-SLANFADM----- 197
           DR   + L+ RA  A   A+ LTVD   +G+R  DI+N   +PP L  L N  D+     
Sbjct: 134 DRGFAKALIERAIAAKCSALVLTVDLQVIGQRHQDIKNGMTVPPQLFKLKNVIDIATKPR 193

Query: 198 ----------KDFAQVKGGAGAS----GLASYVASLIDASLNWNDIAWLKSITRLPILLK 243
                     ++F  + G    S     ++++VAS  DASLNW DI W++SI    +++K
Sbjct: 194 WVKGILGTPRRNFGNIAGHLPGSKDLESVSAWVASQFDASLNWRDIDWIRSIWPGKLIIK 253

Query: 244 GVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRR 303
           G++  EDA+ A++ GA+ + +SNHG RQLDG  ++I+ L E+  +V   I V  D G+R 
Sbjct: 254 GILDVEDAREAVKVGAEALVVSNHGGRQLDGAPSSIEVLPEIVHTVGSHIEVMFDGGIRS 313

Query: 304 GTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDI 362
           G DV++ALALGA + +IGR  ++GL   G  GV + + ++  E    M LCG   + +I
Sbjct: 314 GQDVMRALALGAKSCMIGRAYIYGLGAYGGPGVAKAIDIIGKELSTTMGLCGVNSIHEI 372

gb|AAO45191.1| RH48327p [Drosophila melanogaster]
(241 aa)

Score: 248 bits (634), Expect: 1.57418e-64
Length: 229, Idn/Pos/Gap = 118/160/0 (51%/69%/0%)

Query: 143 KDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANFADMKDFAQ 202
           KDR ITE+LVRRAE+A F+A+ LT+D P  G R AD+RN F LP HLSLANF  +K    
Sbjct:   8 KDRTITEKLVRRAEKANFKALVLTIDAPIFGHRRADVRNNFSLPSHLSLANFQGVKATGV  67

Query: 203 VKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQRALQYGADGI 262
                GASG+  YV+S  D ++ W DIAWLK IT LPI++KGV+TAEDA  A ++G  G+
Sbjct:  68 GNAAMGASGINEYVSSQFDPTITWKDIAWLKGITHLPIVVKGVLTAEDAVLAQEFGCAGL 127

Query: 263 WISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALALGADAVLIGR 322
            +SNHGARQ+D V A+I+ L E+ ++V   + V +D G+ +G D+ KALALGA  V +GR
Sbjct: 128 IVSNHGARQIDTVPASIEALPEIVKAVGDNLVVMLDGGIMQGNDIFKALALGAKTVFVGR 187

Query: 323 PIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLVVRDA 371
           P VWGLA +G++GV  +LS+L+ +F+  M L GCQ + DI   +VV ++
Sbjct: 188 PAVWGLAYNGQKGVEEMLSVLRKDFETTMALIGCQNLGDITSAMVVHES 236

ref|ZP_00177642.2| COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Crocosphaera watsonii WH 8501]
(385 aa)

Score: 248 bits (634), Expect: 1.9072e-64
Length: 370, Idn/Pos/Gap = 148/207/21 (40%/55%/5%)

Query:  15 NLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQV  74
           N  ++   AK RLP  ++ Y    ADDEQT R N EA+      P VL+ V  VD++ +V
Sbjct:   8 NFQDFRTLAKRRLPGPIFNYIDGAADDEQTYRRNTEAYGDCDLIPNVLVGVENVDMSVEV  67

Query:  75 MGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLP 134
           MG  L  P+  APTA+QR+ H EGE A ARA A  GT+ G+SS AT ++E++A  +   P
Sbjct:  68 MGQKLDMPIYCAPTALQRLFHHEGERAVARAAAEYGTMFGVSSLATVTVEEIAK-ITNTP 126

Query: 135 KFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHL---SL 191
           K FQ Y +KDR + + L+ RA  A F  +ALTVDT   G RE D+R  F  PP L   SL
Sbjct: 127 KMFQFYFHKDRGLNDALLERARAANFNVLALTVDTITGGNRERDLRTGFTSPPKLTLDSL 186

Query: 192 ANFA---------------DMKDFAQV--KGGAGASGLASYVASLIDASLNWNDIAWLKS 234
            +FA               DM   +    +G   A  +  Y ++++D S+NW D   L S
Sbjct: 187 MSFATHPTWAWNFLTKEKFDMPHLSGYVSQGTNVAVSVGDYFSTMLDQSMNWKDAEKLCS 246

Query: 235 ITRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIP 294
                  LKG+++ EDA+RA+  G  GI +SNHG RQLDG  +  D L E+  +V  +I 
Sbjct: 247 QWNGQFALKGIMSVEDAKRAVDIGCTGIMVSNHGGRQLDGCRSPFDQLAEICDAVGDKID 306

Query: 295 VFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLC 354
           V  + G++RGT V+KAL++GA A   GR  ++ LA  G+ GV R L  ++ E +  M+L 
Sbjct: 307 VICEGGIQRGTHVLKALSVGAKACSGGRLYLFALAAAGQAGVERALGNMRTEIERDMKLM 366

Query: 355 GCQKVSDIRR 364
           G  K+  + R
Sbjct: 367 GVTKLDQLSR 376

ref|YP_023790.1| lactate 2-monooxygenase [Picrophilus torridus DSM 9790]
gb|AAT43597.1| lactate 2-monooxygenase [Picrophilus torridus DSM 9790]
(384 aa)

Score: 248 bits (633), Expect: 1.9393e-64
Length: 362, Idn/Pos/Gap = 129/215/10 (35%/59%/2%)

Query:  13 PLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITK  72
           P+++ ++H  A  +L    +GY    A    T ++NE +F + R RPR L DVS +D++ 
Sbjct:  22 PVSINDWHDLAMKKLDNGPWGYLEGSAGSNDTEKNNERSFLKYRIRPRYLRDVSNIDMSI  81

Query:  73 QVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPG 132
           ++ G     P ++ P  +  + H +G++A A+A   +G    LS+ ++ S+EDVA   P 
Sbjct:  82 RLFGKRFETPFILGPIGVTSIIHNDGDIAIAKAAENLGMPFALSTVSSYSIEDVAKAAPN 141

Query: 133 LPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHL--S 190
             ++FQLY  +D+ I + ++RRAE++G+ AI +TVDT  LG RE D++N + LP  L   
Sbjct: 142 AERWFQLYPGRDKNIMKSMIRRAEKSGYSAIIVTVDTTMLGWRETDLKNAY-LPFLLGYG 200

Query: 191 LANFADMKDF-AQVKGGAGA---SGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVV 246
           +AN+    +F A++         + +  +++  ++    W+D + ++S TRLP+++KG+ 
Sbjct: 201 IANYITDPEFNARLDKSPEEDMNAAIEEFLSIYVNPGFTWDDFSEIRSWTRLPLIIKGIT 260

Query: 247 TAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVA-QSVRGRIPVFIDSGVRRGT 305
             +D ++A  Y AD + ISNHG RQ+DG  ++ID L E++   + G I    DSG+R   
Sbjct: 261 HIDDVKKAFDYNADAVVISNHGGRQVDGAISSIDALHELSLNDINGTI--LFDSGIRHAA 318

Query: 306 DVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRD 365
           D  KA+ALGA AVLIGRP ++ LAV G+ G+ R +  L+ EF L M L G   +S++ R+
Sbjct: 319 DAFKAIALGASAVLIGRPYIYALAVAGQAGIERYMDQLRSEFNLEMALSGYGSLSELNRE 378

Query: 366 LV 367
            +
Sbjct: 379 TI 380

ref|NP_251072.1| L-lactate dehydrogenase [Pseudomonas aeruginosa PAO1]
gb|AAG05770.1| L-lactate dehydrogenase [Pseudomonas aeruginosa PAO1]
ref|ZP_00140103.2| COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Pseudomonas aeruginosa UCBPP-PA14]
pir||E83348 L-lactate dehydrogenase PA2382 [imported] - Pseudomonas aeruginosa (strain PAO1)
(383 aa)

Score: 248 bits (633), Expect: 2.44966e-64
Length: 370, Idn/Pos/Gap = 137/208/20 (37%/56%/5%)

Query:  22 FAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGIDLSF  81
            A+ R+P M Y Y  SG+  E T R N++ F  ++ R RV  ++    +  +++G +++ 
Sbjct:  13 LARKRVPRMFYDYADSGSWSEGTYRANQDDFAAIKLRQRVARNIENRSLRTRMLGQEMAM  72

Query:  82 PLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFFQLYV 141
           P+ +APT +  M H +GE+  ARA A  G    LS+ +  SLED+A  V G P +FQLYV
Sbjct:  73 PVAIAPTGLAGMQHADGEILAARAAAEFGVRYTLSTMSICSLEDIATEV-GQPFWFQLYV 131

Query: 142 YKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANFADMKD-- 199
            +DR   ERL+ RA+ AG  A+ LT+D   +G+R  D++N    PP  +LAN  ++    
Sbjct: 132 MRDRDFIERLIDRAKAAGCDALVLTLDLQIIGQRHKDLKNGLSAPPRPTLANLLNIATKP 191

Query: 200 -----------------FAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILL 242
                               VKG      L+ + A   D  LNW D+ W+K      ++L
Sbjct: 192 RWALGMLGTRRRGFGNIVGHVKGVDDMGSLSEWTARQFDPRLNWGDVEWIKRRWGGKLVL 251

Query: 243 KGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVR 302
           KG++ AEDA+ A   GAD + +SNHG RQLDG  +TI  L  + ++V  RI V++DSG+R
Sbjct: 252 KGILDAEDARLAADSGADALVVSNHGGRQLDGAPSTISALPAIVEAVGERIEVWLDSGIR 311

Query: 303 RGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDI 362
            G DV+KA+ALGA   +IGRP ++GL   G+ GV R L ++  E  L M  CG   + ++
Sbjct: 312 SGQDVLKAIALGARGTMIGRPYLYGLGALGQAGVTRALEIIARELDLTMAFCGHTDIREV 371

Query: 363 RRDLVVRDAF 372
            RD+++  ++
Sbjct: 372 GRDILLPGSY 381

emb|CAA11762.1| PCZA361.2 [Amycolatopsis orientalis]
pir||T17471 probable (S)-2-hydroxy-acid oxidase (EC 1.1.3.15) - Amycolatopsis orientalis
(357 aa)

Score: 247 bits (631), Expect: 3.30794e-64
Length: 351, Idn/Pos/Gap = 149/208/5 (42%/59%/1%)

Query:  14 LNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQ  73
           ++LA+    A+  LP  ++ + A G+  E +L  N  A  R+   PR+L D++ V     
Sbjct:   4 VSLADLERAARDVLPGEIFDFLAGGSGTEASLVANRTALERVFVIPRMLRDLTDVTTEID  63

Query:  74 VMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGL 133
           + G   + P+ VAP A QR+ HPEGELA ARA    G    + + ++ SLE++AA V G 
Sbjct:  64 IFGRRAALPMAVAPVAYQRLFHPEGELAVARAARDAGVPYTICTLSSVSLEEIAA-VGGR 122

Query: 134 PKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLAN 193
           P +FQLY  +D   +  LVRRAE AG  AI  TVD P +GRR  D+RN F LP  ++ AN
Sbjct: 123 P-WFQLYWLRDEKRSLDLVRRAEDAGCEAIVFTVDVPWMGRRLRDMRNGFALPEWVTAAN 181

Query: 194 FADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQR 253
           F      A  +   G S +A + A    A   W  +  +++ T LP++LKG++  EDA+R
Sbjct: 182 FD--AGTAAHRRTQGVSAVADHTAREF-APATWESVEAVRAHTDLPVVLKGILAVEDARR 238

Query: 254 ALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALAL 313
           A+  GA GI +SNHG RQLDG    I+ L E+  +V G   V +D G+R G DV+KA AL
Sbjct: 239 AVDAGAGGIVVSNHGGRQLDGAVPGIEMLGEIVAAVSGGCEVLVDGGIRSGGDVLKATAL 298

Query: 314 GADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRR 364
           GA AVL+GRP++W LA  G++GV +LL LL +E + AM L GC+ V   RR
Sbjct: 299 GASAVLVGRPVMWALAAAGQDGVRQLLELLAEEVRDAMGLAGCESVGAARR 349

ref|NP_358221.1| Lactate oxidase [Streptococcus pneumoniae R6]
gb|AAK99431.1| Lactate oxidase [Streptococcus pneumoniae R6]
pir||C97950 lactate oxidase (EC 1.1.3.-) [imported] - Streptococcus pneumoniae (strain R6)
(378 aa)

Score: 247 bits (630), Expect: 4.50436e-64
Length: 361, Idn/Pos/Gap = 135/198/9 (37%/54%/2%)

Query:  14 LNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQ  73
           +N  +    A+  +P   +GY ASGA+D  TLR+N  AF      P  L DV       +
Sbjct:  15 INTYDLEPMAQQVIPKAAFGYIASGAEDTFTLRENIRAFNHKLIVPHTLCDVENPSTEIE  74

Query:  74 VMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGL 133
             G  LS P+++AP A  ++A+ +GE+ATAR V   G++   SS++T  L +++  + G 
Sbjct:  75 FAGEKLSSPIIMAPVAAHKLANEQGEVATARGVHEFGSLYTTSSYSTVDLPEISEALQGT 134

Query: 134 PKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLAN 193
           P +FQ Y  KD  I   ++ R +  G++AI LT D    G RE D RN F  P  + +  
Sbjct: 135 PHWFQFYFSKDDGINRHIMDRVKAEGYKAIVLTADATVGGNREVDKRNGFVFPVGMPIVE 194

Query: 194 FADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQR 253
                    +  GAG S    +V       L+  D+ ++   + LP+ +KG    ED +R
Sbjct: 195 -------EYLPEGAGKS--MDFVYKSAKQRLSPRDVEFIAEYSGLPVYVKGPQCREDVER 245

Query: 254 ALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALAL 313
           +L  GA GIW++NHG RQ+DG  A  D L+EVA++V  R+P+  DSGVRRG  V KALA 
Sbjct: 246 SLAAGASGIWVTNHGGRQIDGGPAAFDSLQEVAEAVDRRVPIVFDSGVRRGQHVFKALAS 305

Query: 314 GADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLVVRDAFA 373
           GAD V IGRP+++GLA+ G  GV ++   L  E K  MQL G Q + D++   +  + + 
Sbjct: 306 GADLVAIGRPVIYGLALGGSVGVRQVFEHLNAELKTVMQLSGAQTIEDVKHFKLRHNPYN 365

Query: 374 P 374
           P
Sbjct: 366 P 366

ref|YP_169352.1| L-lactate dehydrogenase [Francisella tularensis subsp. tularensis Schu 4]
emb|CAG44936.1| L-lactate dehydrogenase [Francisella tularensis subsp. tularensis SCHU S4]
(385 aa)

Score: 247 bits (630), Expect: 4.50436e-64
Length: 365, Idn/Pos/Gap = 131/200/24 (35%/54%/6%)

Query:  26 RLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGIDLSFPLMV  85
           R+P M   Y  +G+  +QTL+ N++ F    FR +VL D+    +  +++G +   PL+ 
Sbjct:  21 RVPKMFVDYCEAGSWQQQTLKYNQQDFGNYLFRQKVLTDIQNRSLKTKILGQEYKMPLVF  80

Query:  86 APTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFFQLYVYKDR 145
           AP  +  M H +GE+  ARA  + G    LS+ +  S E+VA H    P +FQLY+ KDR
Sbjct:  81 APIGLLGMQHADGEIHAARAAEKFGIPFTLSTMSICSTEEVAKHTTK-PFWFQLYMMKDR 139

Query: 146 AITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLAN------------ 193
                L+  A+ AG  A+ LT D   LG R ADI+N   +PP  +L N            
Sbjct: 140 KFMANLIASAKHAGCSALVLTADLQMLGDRHADIKNGLTVPPKPTLKNLINLSTKVPWCL 199

Query: 194 ---------FADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKG 244
                    F ++ + A  KGG  +  L  +     D SLNW+D+ W++      +++KG
Sbjct: 200 NMLKTSNRTFGNIVNHAANKGGFAS--LGKWTNEQFDLSLNWHDVEWVQKQWNGRMIIKG 257

Query: 245 VVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRG 304
           ++  +DA  A   GAD I +SNHG RQLDG  ++I  LEE+  +V  ++ V IDSG+R G
Sbjct: 258 IMDTQDAIMAQNTGADAIVVSNHGGRQLDGAPSSISVLEEIIDAVDRKLEVLIDSGIRTG 317

Query: 305 TDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRR 364
            D++KA ALGA A LIGRP+V+GL   GE+G YR+L +   E    M  CG   ++++ +
Sbjct: 318 QDLLKAKALGATAGLIGRPMVYGLGAYGEQGAYRVLEIFYQEMDKTMAFCGHTNINNVDK 377

Query: 365 DLVVR 369
            ++++
Sbjct: 378 SILIK 382

ref|ZP_00384906.1| COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Lactobacillus casei ATCC 334]
(371 aa)

Score: 247 bits (630), Expect: 5.27815e-64
Length: 351, Idn/Pos/Gap = 140/207/10 (39%/58%/2%)

Query:  14 LNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQ  73
           LNL      AK  +P   YGY   G++DE TL +N +AF   +   + L ++   D++  
Sbjct:  19 LNLPSLADEAKKIIPTGGYGYIVGGSEDEWTLAENTKAFNHAQIVHKALSNIDSPDLSTN  78

Query:  74 VMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGL 133
            +GIDL  P+M+APTA Q +AH +GE  TAR VA +G +M  S++++TS+ D AA   G 
Sbjct:  79 FLGIDLKTPIMMAPTAAQGLAHSQGEKDTARGVAAVGGLMAQSTYSSTSIADTAAAGNGA 138

Query: 134 PKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLP-PHLSLA 192
           P+ FQLY+ KD    + L+  A++AG + I LTVD    G RE DI N FQ P P  +L 
Sbjct: 139 PQLFQLYMSKDWDFNKSLLDEAKKAGVKGIILTVDATVDGYREEDIINNFQFPIPMPNLE 198

Query: 193 NFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQ 252
            ++         G     G+    AS     ++ +D+  +   T LP+++KGV + EDA 
Sbjct: 199 KYS--------AGDGKGKGIGEIYASAAQ-KISEDDVRRIAEYTDLPVIVKGVQSPEDAL 249

Query: 253 RALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALA 312
           RA+  GA  I++SNHG RQL+G  A+ D L  +A++V  R+P+  DSGVRRG+   KALA
Sbjct: 250 RAIGAGAAAIYVSNHGGRQLNGGPASFDVLPAIAKAVNKRVPIIFDSGVRRGSHAFKALA 309

Query: 313 LGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIR 363
            GAD V  GRP+++GLA+ G EGV  +   +  E ++ MQL G + ++D++
Sbjct: 310 AGADLVAFGRPVIYGLALGGAEGVQSVFEQIDHELEIIMQLAGTKTIADVK 360

ref|ZP_00280744.1| COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Burkholderia fungorum LB400]
(406 aa)

Score: 247 bits (630), Expect: 5.27815e-64
Length: 369, Idn/Pos/Gap = 143/205/20 (38%/55%/5%)

Query:  22 FAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGIDLSF  81
            A+ R+P + Y Y  SG+  E T R NE     LRFR RV  +V  +     ++G   S 
Sbjct:  14 LARRRVPKIFYDYVDSGSWTESTYRANETDLGSLRFRQRVGCNVEAIRTASTLLGHACSL  73

Query:  82 PLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFFQLYV 141
           PL +APT +  M H +GE+  ARA AR G    LS+ +  S+EDVA  V   P +FQLY+
Sbjct:  74 PLALAPTGLAGMVHADGEILAARAAARFGVPFTLSTVSICSIEDVAEQV-AQPFWFQLYM 132

Query: 142 YKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANFADM---- 197
            KDR    RL+ RA  AG  A+ LT+D P  G+R  D+RN   +PP L++ N + M    
Sbjct: 133 MKDRDFIVRLIERARDAGCSALVLTLDLPIQGQRHKDVRNGLSVPPKLNVRNLSTMLSRP 192

Query: 198 -----------KDFAQV----KGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILL 242
                      + F  +    KG +     A +V+   D S+ W+D+ W+K      +++
Sbjct: 193 AWCARMLGTRRRTFGNIVGHAKGVSDTFAFAEWVSRQFDRSVTWDDVRWIKRHWGGRLIV 252

Query: 243 KGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVR 302
           KG++ A+DA+ A+  GAD I +SNHG RQLDG  ++I  L  +A +V  +  V +D G+R
Sbjct: 253 KGILDADDARLAVAAGADAIVVSNHGGRQLDGAPSSISALPAIAAAVGRQTEVLMDGGIR 312

Query: 303 RGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDI 362
            G DV++ALA GA  V+IGR  ++GL   GE GV R L L++ E +  M LCG   V+D+
Sbjct: 313 SGQDVLRALAWGAHGVMIGRAFLYGLGALGEAGVTRTLELIQKELESTMALCGITDVADV 372

Query: 363 RRDLVVRDA 371
            RD +V  A
Sbjct: 373 GRDAIVSPA 381

ref|ZP_00285101.1| COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Burkholderia fungorum LB400]
(394 aa)

Score: 246 bits (628), Expect: 7.61943e-64
Length: 381, Idn/Pos/Gap = 146/215/35 (38%/56%/9%)

Query:  11 TQPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDI  70
           ++PLN+ +Y   A+ RLP +V+ Y   GA+DE  L+ N +AFR ++F+PR L+D+S+   
Sbjct:   2 SKPLNIEDYRRLARKRLPRIVFDYLDGGAEDEIGLQHNRDAFRSVKFQPRRLVDISKRTT  61

Query:  71 TKQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHV 130
           T  + G  ++ PL++APT +  +  P+G+LA  RA  +      LS+ +T+S+E VA   
Sbjct:  62 TASLFGKSVTAPLVIAPTGLNGIFWPDGDLALVRAAGKFDIPFALSTASTSSIEKVADAA 121

Query: 131 PGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLS 190
            G   +FQLYV   R + E LV+RA  AG+  + LT D    G+RE D RN F +P   S
Sbjct: 122 TG-DIWFQLYVVH-RKLAELLVKRALAAGYSTLVLTTDVGVNGKRERDARNGFGMPIKYS 179

Query: 191 ------------------------LANFADMKDFAQVKGGAGASGLASYVASLIDASLNW 226
                                   LANFA   D  Q          A+ ++  +DAS  W
Sbjct: 180 PRTIVDGILHPRWSLDLVRHGVPQLANFA--SDHVQ-----DTELQAALMSRQMDASFAW 232

Query: 227 NDIAWLKSITRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVA 286
           +D+ WL+ +    +L+KG+  A+DA R    GADG+ +SNHG RQLD   A I+ L E A
Sbjct: 233 DDLKWLRDLWPRTLLIKGISRADDAARCFSLGADGVILSNHGGRQLDSAIAPIEALRETA 292

Query: 287 QSVRGRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDE 346
             +    P+ IDSG+RRG+DVVKALALGA AVL+GR  ++GLA  GE GV  +LS++++E
Sbjct: 293 AQLHK--PILIDSGIRRGSDVVKALALGAQAVLLGRATLYGLASRGEAGVADVLSIIQNE 350

Query: 347 FKLAMQLCGCQKVSDIRRDLV 367
             + +   GC   + +  D +
Sbjct: 351 IDITLAQIGCTDAASVTSDFL 371

emb|CAC48372.1| putative phenylglycolate oxidase [Amycolatopsis balhimycina]
(358 aa)

Score: 246 bits (628), Expect: 8.63529e-64
Length: 351, Idn/Pos/Gap = 151/211/5 (43%/60%/1%)

Query:  14 LNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQ  73
           ++L +    A+  LP  ++ + A G+  E +L  N  A  R+   PR+L D++      +
Sbjct:   4 VSLGDLERAARDVLPGEIWDFLAGGSGAEASLTANRTALDRVFVVPRMLCDLTGSTTEAE  63

Query:  74 VMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGL 133
           ++G   + P+ VAP A QR+ HPEGELA ARA    G    + + ++  LE+VAA V G 
Sbjct:  64 LLGRRAALPMAVAPVAYQRLFHPEGELAAARAARDAGVPYTICTLSSVPLEEVAA-VGGR 122

Query: 134 PKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLAN 193
           P +FQLY  +D   +  LVRRAE AG  AI  TVD P +GRR  D+RN F LP  ++ AN
Sbjct: 123 P-WFQLYWLRDEKRSLELVRRAEDAGCEAIVFTVDVPWMGRRWRDMRNGFALPESVTAAN 181

Query: 194 FADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQR 253
           F D    A  +   GAS +A + A    A   W  +A +++ T LP++LKG++ AEDA+R
Sbjct: 182 F-DAGSAAH-RRTRGASAVADHTAREF-APATWESVATVRAHTDLPVVLKGILAAEDARR 238

Query: 254 ALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALAL 313
           A++ GADGI +SNHG RQLDG    I+ L E+A  V GR  V +D G+R G D++KA AL
Sbjct: 239 AVEAGADGIVVSNHGGRQLDGAVPGIEVLGEIAAEVSGRCEVLLDGGIRTGGDILKAAAL 298

Query: 314 GADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRR 364
           GA  VL+GRP++WGLA  G+EGV ++  LL  E + A+ L GC  VS   R
Sbjct: 299 GASGVLVGRPVMWGLAAAGQEGVRQVFELLAAELRNALGLAGCDSVSAAGR 349

ref|NP_345216.1| lactate oxidase [Streptococcus pneumoniae TIGR4]
gb|AAK74856.1| lactate oxidase [Streptococcus pneumoniae TIGR4]
pir||G95082 lactate oxidase [imported] - Streptococcus pneumoniae  (strain TIGR4)
(378 aa)

Score: 245 bits (626), Expect: 1.29968e-63
Length: 361, Idn/Pos/Gap = 134/198/9 (37%/54%/2%)

Query:  14 LNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQ  73
           +N  +    A+  +P   +GY ASGA+D  TLR+N  AF      P  L +V       +
Sbjct:  15 INTYDLEPMAQQVIPKAAFGYIASGAEDTFTLRENIRAFNHKLIVPHTLCNVENPSTEIE  74

Query:  74 VMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGL 133
             G  LS P+++AP A  ++A+ +GE+ATAR V   G++   SS++T  L +++  + G 
Sbjct:  75 FAGEKLSSPIIMAPVAAHKLANEQGEVATARGVHEFGSLYTTSSYSTVDLPEISEALQGT 134

Query: 134 PKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLAN 193
           P +FQ Y  KD  I   ++ R +  G++AI LT D    G RE D RN F  P  + +  
Sbjct: 135 PHWFQFYFSKDDGINRHIMDRVKAEGYKAIVLTADATVGGNREVDKRNGFVFPVGMPIVE 194

Query: 194 FADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQR 253
                    +  GAG S    +V       L+  D+ ++   + LP+ +KG    ED +R
Sbjct: 195 -------EYLPEGAGKS--MDFVYKSAKQRLSPRDVEFIAEYSGLPVYVKGPQCREDVER 245

Query: 254 ALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALAL 313
           +L  GA GIW++NHG RQ+DG  A  D L+EVA++V  R+P+  DSGVRRG  V KALA 
Sbjct: 246 SLAAGASGIWVTNHGGRQIDGGPAAFDSLQEVAEAVDRRVPIVFDSGVRRGQHVFKALAS 305

Query: 314 GADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLVVRDAFA 373
           GAD V IGRP+++GLA+ G  GV ++   L  E K  MQL G Q + D++   +  + + 
Sbjct: 306 GADLVAIGRPVIYGLALGGSVGVRQVFEHLNAELKTVMQLSGTQTIEDVKHFKLRHNPYN 365

Query: 374 P 374
           P
Sbjct: 366 P 366

emb|CAC41891.1| PUTATIVE L-LACTATE DEHYDROGENASE (CYTOCHROME) PROTEIN [Sinorhizobium meliloti]
ref|NP_384560.1| PUTATIVE L-LACTATE DEHYDROGENASE (CYTOCHROME) PROTEIN [Sinorhizobium meliloti 1021]
(403 aa)

Score: 245 bits (625), Expect: 1.62807e-63
Length: 370, Idn/Pos/Gap = 145/211/20 (39%/57%/5%)

Query:  15 NLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQV  74
           N  ++   AK RLP+ ++ Y    ADDE T R N  AF      P VL  V  VD++  V
Sbjct:  30 NFHDFRRMAKRRLPSPIFNYIDGAADDEVTYRRNTAAFEGCDLVPNVLRGVGDVDMSVTV  89

Query:  75 MGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLP 134
           MG  L+ P+  +PTA+QR+ H +GE A A A A+ GT+ G+SS  T SLE+ A  +   P
Sbjct:  90 MGQRLAMPVYCSPTALQRLFHHQGERAVAAAAAKFGTMFGVSSLGTVSLEE-ARRICDGP 148

Query: 135 KFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLA-- 192
           + +Q Y +KDR +   ++ RA++AG   + LTVD+   G RE D R  F +P  L+LA  
Sbjct: 149 QVYQFYFHKDRGLNREMMARAKQAGIEVMMLTVDSITGGNRERDKRTGFAIPFKLNLAGI 208

Query: 193 -----------NFADMKDFA------QVKGGAGASGLASYVASLIDASLNWNDIAWLKSI 235
                      N+   + F        V  G GA  ++ Y   ++D S++W+D+A +   
Sbjct: 209 TQFAIKPSWAVNYVRHEPFRLPQLENHVDMGRGAMSISRYFTEMLDPSMSWDDVAEMVQH 268

Query: 236 TRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPV 295
                 LKGV++ EDA+RA++ G  GI +SNHG RQLDG     D L+E+ Q+V  RI V
Sbjct: 269 WGGQFCLKGVISVEDAKRAVEIGCTGIVLSNHGGRQLDGSRTAFDQLDEIVQAVGDRIDV 328

Query: 296 FIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCG 355
            +D GV+RGT V+KAL+LGA AV +GR  ++ LA  G+ GV R L L++ E +  M+L G
Sbjct: 329 MMDGGVQRGTHVLKALSLGAKAVGLGRYYLFPLAAAGQAGVERALELMRVEIERGMKLMG 388

Query: 356 CQKVSDIRRD 365
           C  V ++ ++
Sbjct: 389 CSSVDELTKE 398

ref|NP_355276.1| hypothetical protein AGR_C_4216 [Agrobacterium tumefaciens str. C58]
ref|NP_532991.1| L-lactate dehydrogenase [Agrobacterium tumefaciens str. C58]
gb|AAL43307.1| L-lactate dehydrogenase [Agrobacterium tumefaciens str. C58]
gb|AAK88061.1| AGR_C_4216p [Agrobacterium tumefaciens str. C58]
pir||D97638 l-lactate dehydrogenase (PA2382) [imported] - Agrobacterium tumefaciens (strain C58, Cereon)
pir||AE2861 L-lactate dehydrogenase lldA [imported] - Agrobacterium tumefaciens (strain C58, Dupont)
(382 aa)

Score: 245 bits (625), Expect: 2.07377e-63
Length: 373, Idn/Pos/Gap = 135/211/20 (36%/56%/5%)

Query:  14 LNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQ  73
           L +A+    A+ R+P M + Y  SGA  E T R NE+ F +++ R RVL+D++   +  +
Sbjct:  10 LTIADLKQQAQRRVPKMFFDYADSGAWTESTYRANEDDFAKIKLRQRVLVDMTDRSLATE  69

Query:  74 VMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGL 133
           ++G  +S P+ ++PT +  M H +GE+  A+A    G    LS+ +  S+EDVA+ V   
Sbjct:  70 MVGEKVSMPVALSPTGLTGMQHADGEMLAAKAAEEFGVPFTLSTMSICSIEDVAS-VTSK 128

Query: 134 PKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLAN 193
           P +FQLYV KDR     L+ RA+ AG  A+ LT+D   LG+R  D+RN    PP  +  +
Sbjct: 129 PFWFQLYVMKDRDFVNNLIDRAKAAGCSALVLTLDLQILGQRHKDLRNGLSAPPKFTPKH 188

Query: 194 FADM---------------KDFAQVKGGA----GASGLASYVASLIDASLNWNDIAWLKS 234
              M               + F  + G A      S L+++ A   D  L+W D+ W+K 
Sbjct: 189 IWQMATRPQWCMDMARTKRRSFGNIVGHAKNVSDLSSLSTWTAEQFDPRLSWQDVEWIKQ 248

Query: 235 ITRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIP 294
                ++LKG++  EDA+ A+  GAD I +SNHG RQLDG  ++I  L ++  +V  RI 
Sbjct: 249 RWGGKLILKGILDEEDARAAIDTGADAIIVSNHGGRQLDGAHSSIAMLPKIVDAVGDRIE 308

Query: 295 VFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLC 354
           V +D G+R G DV+KA+ALGA    IGRP ++GL   G++GV   L +++ E  ++M LC
Sbjct: 309 VHMDGGIRSGQDVLKAVALGARGTYIGRPFLYGLGAGGKQGVTTALEIIRKELDISMALC 368

Query: 355 GCQKVSDIRRDLV 367
           G + ++D+ R ++
Sbjct: 369 GKRLITDVDRSIL 381

ref|YP_207778.1| putative L-lactate dehydrogenase [Neisseria gonorrhoeae FA 1090]
gb|AAW89366.1| putative L-lactate dehydrogenase [Neisseria gonorrhoeae FA 1090]
(390 aa)

Score: 244 bits (624), Expect: 2.29215e-63
Length: 366, Idn/Pos/Gap = 132/207/20 (36%/56%/5%)

Query:  16 LAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVM  75
           + + H  AK ++P M Y Y  SG+  E T R+N   F+ +RFR +VL+++    +  +++
Sbjct:  11 IEDLHRVAKRKMPRMFYDYIDSGSWTETTYRENTSDFKDIRFRQKVLVNMEGRSLETKMI  70

Query:  76 GIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPK 135
           G D+  P+ +APT    MAH +GE+  ARA  + G    LS+ +  S+EDVA +    P 
Sbjct:  71 GGDVKMPVAIAPTGFTGMAHADGEILAARAAEKFGIPFTLSTMSICSIEDVAENTSA-PF 129

Query: 136 FFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANFA 195
           +FQLYV +DR   E L++RA+ A   A+ LT D   LG+R  DI+N    PP  ++AN  
Sbjct: 130 WFQLYVMRDREFMENLIKRAKDAKCSALVLTADLQVLGQRHKDIKNGLSAPPKPTIANLI 189

Query: 196 DM---------------KDFAQVKGGAGASG----LASYVASLIDASLNWNDIAWLKSIT 236
           ++               + F  + G A   G    L+S+ A   D  L+W+D+A +K + 
Sbjct: 190 NLATKPEWCMKMLNTERRTFRNIVGHAKNVGDLSSLSSWTAEQFDPRLSWDDVARIKDLW 249

Query: 237 RLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVF 296
              +++KG++  EDA++A + GAD + +SNHG RQLD   + I  L ++  +V   I V+
Sbjct: 250 GGKLIIKGIMEPEDAEKAAKSGADALVVSNHGGRQLDDTVSAIKALPDIVSAVGSDIEVW 309

Query: 297 IDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGC 356
           +DSG+R G D++KA ALGA   +IGR  ++GL   GEEGV R L +L  E  ++M   G 
Sbjct: 310 MDSGIRSGQDILKAWALGAKGTMIGRAFLYGLGAYGEEGVTRALEILYKEMDVSMAFTGH 369

Query: 357 QKVSDI 362
           + + D+
Sbjct: 370 RDIQDV 375

ref|ZP_00145614.1| COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Psychrobacter sp. 273-4]
(402 aa)

Score: 244 bits (624), Expect: 2.59775e-63
Length: 372, Idn/Pos/Gap = 131/214/23 (35%/57%/6%)

Query:  23 AKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGIDLSFP  82
           A+ ++P M Y Y  SG+  E T R+NE  F R++ R RVL+++    +  +++G  +  P
Sbjct:  17 AQRKIPRMFYDYVDSGSWTETTYRNNETDFDRIKLRQRVLVNMEGRSLATEMLGTPVKMP  76

Query:  83 LMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFFQLYVY 142
           + +APT    M   +GE+  A+A  + G    LS+ +  S+EDVA H    P +FQLY+ 
Sbjct:  77 VAIAPTGFTGMMWADGEILAAQAAEKFGVPFSLSTMSICSIEDVAEHT-SQPFWFQLYMM 135

Query: 143 KDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANFADM----- 197
           +D      L+RRA+ A   A+ LT D   LG+R  DI+N    PP  +LAN  ++     
Sbjct: 136 RDMDFIANLIRRAKEANCSALILTADLQVLGQRHKDIKNGLSAPPKPTLANILNLMTKPE 195

Query: 198 ----------KDFAQVKGGA----GASGLASYVASLIDASLNWNDIAWLKSITRLPILLK 243
                     + F  + G A      S L+++ A   D +L+W+D+A +K +    +++K
Sbjct: 196 WCMNMLGTKRRTFGNIVGHAKNVEDISSLSAWTAEQFDPALSWDDVARIKDMWGGKLIIK 255

Query: 244 GVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRG---RIPVFIDSG 300
           G++  EDA  A + GAD + +SNHG RQLDG  ++I  L ++ Q+VR    +I +++DSG
Sbjct: 256 GIMEPEDAVLAARSGADALVVSNHGGRQLDGAPSSISSLADIVQAVRAEDSQIEIWLDSG 315

Query: 301 VRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVS 360
           +R G DV+KA+ALGA+  +IGR  ++GL   GE+GV R L L+ +E  ++M  CG   ++
Sbjct: 316 IRSGQDVLKAMALGANGTMIGRAFLYGLGAYGEDGVRRALELIYNECDISMAFCGHTDIN 375

Query: 361 DIRRDLVVRDAF 372
           ++R D++V+  +
Sbjct: 376 EVRDDILVKGTY 387

ref|NP_965805.1| glycolate oxidase [Lactobacillus johnsonii NCC 533]
gb|AAS09771.1| glycolate oxidase [Lactobacillus johnsonii NCC 533]
(412 aa)

Score: 244 bits (622), Expect: 4.35777e-63
Length: 353, Idn/Pos/Gap = 134/205/11 (37%/58%/3%)

Query:  14 LNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQ  73
           +NL E    AK  +P   Y Y ASGA++E T R+N +AF   +  PR L  +   ++  +
Sbjct:  20 VNLDELENEAKYVMPEAAYYYVASGAENEWTWRNNTQAFNHFQIVPRALTGMQNPELNTE  79

Query:  74 VMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGL 133
            +G+ L  P+M+ P A   +A+ E E+ TA+     G +  +S++A  S+++V + V   
Sbjct:  80 FLGMKLKTPVMICPIACHGIANAEAEIDTAKGAKAAGALFAMSTYANKSVQEVQSAVGDS 139

Query: 134 PKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLAN 193
           P+F QLY+ K+    + ++  + +AGF    LTVD    G REA++R  F  P  L+   
Sbjct: 140 PRFMQLYLSKNWDFNKMVIEESVKAGFTGFFLTVDALVSGYREANLRTNFTYPVPLAF-- 197

Query: 194 FADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQR 253
                 F +  GG G     + + +    ++  +DI  +K I  +P+++KGV  AEDA  
Sbjct: 198 ------FNEWNGGKGEGQSVAQMYASSAQNIGPDDIRKIKEIADVPVIVKGVECAEDAML 251

Query: 254 ALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRG---RIPVFIDSGVRRGTDVVKA 310
           A+  GADGI +SNHG R++DG  ATID L E+A++VR    R+P+ +D GVRRG+ V KA
Sbjct: 252 AIGAGADGIVVSNHGGREVDGAPATIDVLPEIAKAVRSSNHRVPIILDGGVRRGSHVFKA 311

Query: 311 LALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIR 363
           LALGAD V IGRP ++GLA+ G +GV  ++  L  E  + MQL GC+ + DI+
Sbjct: 312 LALGADLVGIGRPFLYGLALGGAQGVQSVIEQLNKELLIDMQLTGCKTIEDIK 364

pdb|1QCW|B Chain B, Flavocytochrome B2, Arg289lys Mutant
pdb|1QCW|A Chain A, Flavocytochrome B2, Arg289lys Mutant
(410 aa)

Score: 244 bits (622), Expect: 4.65858e-63
Length: 374, Idn/Pos/Gap = 138/221/18 (36%/59%/4%)

Query:   4 KPAVNPATQPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLI  63
           K  + P    +NL ++   A   L    + YY+SGA+DE T R+N  A+ R+ F+P++L+
Sbjct:  12 KSLLPPLDNIINLYDFEYLASQTLTKQAWAYYSSGANDEVTHRENHNAYHRIFFKPKILV  71

Query:  64 DVSRVDITKQVMGIDLSFPLMVAPTAMQRMAHP-EGELATARAVARIGTVMG--LSSWAT 120
           DV +VDI+  ++G  +  P  V+ TA+ ++ +P EGE   AR   +  T +   +S+ A+
Sbjct:  72 DVRKVDISTDMLGSHVDVPFYVSATALCKLGNPLEGEKDVARGCGQGVTKVPQMISTLAS 131

Query: 121 TSLEDVAAHVPGLPK--FFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREAD 178
            S E++    P   +  ++QLYV  DR IT+ LV+  E+ G +A+ +TVD P LG++E D
Sbjct: 132 CSPEEIIEAAPSDKQIQWYQLYVNSDRKITDDLVKNVEKLGVKALFVTVDAPSLGQKEKD 191

Query: 179 IRNQFQLPPHLSLANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRL 238
           ++ +F      + A F  MK    V+   GAS     ++  ID SL W DI  LK  T+L
Sbjct: 192 MKLKFSN----TKAGFKAMKK-TNVEESQGAS---RALSKFIDPSLTWKDIEELKKKTKL 243

Query: 239 PILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEV-----AQSVRGRI 293
           PI++KGV   ED  +A + G  G+ +SNHG RQLD   A I+ L E       ++++ ++
Sbjct: 244 PIVIKGVQRTEDVIKAAEIGVSGVVLSNHGGRQLDFSRAPIEVLAETMPILEQRNLKDKL 303

Query: 294 PVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQL 353
            VF+D GVRRGTDV+KAL LGA  V +GRP ++  +  G  GV + + +L+DE +++M+L
Sbjct: 304 EVFVDGGVRRGTDVLKALCLGAKGVGLGRPFLYANSCYGRNGVEKAIEILRDEIEMSMRL 363

Query: 354 CGCQKVSDIRRDLV 367
            G   +++++ DL+
Sbjct: 364 LGVTSIAELKPDLL 377

gb|AAC33509.1| glycolate oxidase [Nicotiana tabacum]
pir||T04121 (S)-2-hydroxy-acid oxidase (EC 1.1.3.15), peroxisomal - common tobacco (fragment)
(217 aa)

Score: 243 bits (621), Expect: 4.77666e-63
Length: 212, Idn/Pos/Gap = 128/166/4 (60%/78%/1%)

Query:  15 NLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQV  74
           N+ EY   AK +LP MV+ YYASGA+D+ TL +N  AF R+ FRPR+LIDVS++D++  V
Sbjct:   6 NVMEYEAIAKKKLPKMVFDYYASGAEDQWTLAENRNAFSRILFRPRILIDVSKMDMSTTV  65

Query:  75 MGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLP 134
           +G  +S P+M+APTAMQ+MAHPEGE ATARA +  GT+M LSSWAT+S+E+VA+  PG+ 
Sbjct:  66 VGFKISMPIMIAPTAMQKMAHPEGEYATARAASAAGTIMTLSSWATSSVEEVASTGPGI- 124

Query: 135 KFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANF 194
           +FFQLYVYKDR +  +LVRRAERAGF+AIAL +DTP+LGRREADI+N+F LPP L+L NF
Sbjct: 125 RFFQLYVYKDRNVVAQLVRRAERAGFKAIAL-IDTPRLGRREADIKNRFVLPPFLTLKNF 183

Query: 195 ADMKDFAQVKGGAGASGLASYVASLIDASLNW 226
             + D  ++   A  SGLASYVA  ID +L+W
Sbjct: 184 EGL-DLGKMD-QASDSGLASYVAGQIDRTLSW 213

emb|CAA68903.1| lactate oxidase [Streptococcus iniae]
(403 aa)

Score: 243 bits (621), Expect: 4.81668e-63
Length: 350, Idn/Pos/Gap = 132/197/10 (37%/56%/2%)

Query:  14 LNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQ  73
           +N+ +    A+  +P   +GY ASGA D  TL +N  +F   +  P  L  V        
Sbjct:  27 VNVFDLEKMAQKVIPKGAFGYIASGAGDTFTLHENIRSFNH-KLIPHGLKGVENPSTEIT  85

Query:  74 VMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGL 133
            +G  L+ P+++AP A  ++A+ +GE+A+A+ V   GT+   SS++TT L +++  +   
Sbjct:  86 FIGDKLASPIILAPVAAHKLANEQGEIASAKGVKEFGTIYTTSSYSTTDLPEISQTLGDS 145

Query: 134 PKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLAN 193
           P +FQ Y  KD  I   ++ R +  G ++I LTVD    G RE D RN F  P  + +  
Sbjct: 146 PHWFQFYYSKDDGINRHIMDRLKAEGVKSIVLTVDATVGGNREVDKRNGFVFPVGMPIVQ 205

Query: 194 FADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQR 253
                    +  GAG +    YV      +L+  D+ ++   + LP+ +KG   AEDA R
Sbjct: 206 -------EYLPNGAGKT--MDYVYKATKQALSPKDVEYIAQYSGLPVYVKGPQCAEDAFR 256

Query: 254 ALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALAL 313
           AL+ GA GIW++NHG RQLDG  A  D L+EVA+SV  R+P+  DSGVRRG  V KALA 
Sbjct: 257 ALEAGASGIWVTNHGGRQLDGGPAAFDSLQEVAESVDRRVPIVFDSGVRRGQHVFKALAS 316

Query: 314 GADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIR 363
           GAD V +GRP+++GLA+ G  G  ++   + DE K+ MQL G Q + D++
Sbjct: 317 GADLVALGRPVIYGLAMGGSVGTRQVFEKINDELKMVMQLAGTQTIDDVK 366

ref|ZP_00287086.1| COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Enterococcus faecium]
(367 aa)

Score: 243 bits (621), Expect: 5.10638e-63
Length: 352, Idn/Pos/Gap = 138/202/11 (39%/57%/3%)

Query:  14 LNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQ  73
           +N+ +  + A   +PA  YGY +SGA D  T ++NE AF      P VL DV   D T  
Sbjct:  17 INMEDLEIAASQVIPAGGYGYISSGAGDLFTYQENERAFNHRLIIPHVLRDVELPDTTTH  76

Query:  74 VMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDV-AAHVPG 132
                L+ P+++AP A   +AH + E A+A+ VA  GT+   SS+A+ +LE++  A    
Sbjct:  77 FDEEMLTAPIIMAPVAAHGLAHVKAEKASAKGVADFGTIYTASSYASCTLEEIREAGGEK 136

Query: 133 LPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLA 192
            P++FQ Y+ KD  I   ++  A+R G +AI LT D    G RE D RN F  P  + + 
Sbjct: 137 APQWFQFYMSKDNGINLDILEVAKRNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIV 196

Query: 193 NFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQ 252
                      + G G +  A Y +S     L+  D+ ++ + + LP+ +KGV + ED  
Sbjct: 197 Q--------AYQSGVGQTMDAVYKSS--KQKLSPKDVEFIAAHSDLPVYVKGVQSEEDVY 246

Query: 253 RALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALA 312
           R+L+ GA GIW+SNHG RQLDG  A  D L+ VA++V  R+P+  DSGVRRG  V KA+A
Sbjct: 247 RSLESGAGGIWVSNHGGRQLDGGPAAFDSLQYVAEAVDKRVPIVFDSGVRRGQHVFKAIA 306

Query: 313 LGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRR 364
            GAD V IGRP+++GL++ G  GV+++    K E ++ MQL G Q V DI++
Sbjct: 307 SGADLVAIGRPVIYGLSLGGSTGVHQVFDFFKTELEMVMQLAGTQTVEDIKK 358

ref|NP_774049.1| L-lactate dehydrogenase [Bradyrhizobium japonicum USDA 110]
dbj|BAC52674.1| L-lactate dehydrogenase [Bradyrhizobium japonicum USDA 110]
(378 aa)

Score: 243 bits (621), Expect: 5.32392e-63
Length: 358, Idn/Pos/Gap = 132/201/20 (36%/56%/5%)

Query:  24 KARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGIDLSFPL  83
           K R+P   + Y   G+  E+TLR N E  + ++FR R+L+DVS+ D +  ++G   + PL
Sbjct:  15 KRRVPKAFFDYCDRGSYAEETLRANREDMQAIKFRQRILVDVSKRDTSTTILGETSTMPL  74

Query:  84 MVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFFQLYVYK 143
           ++AP  +  M H +GE+   RA    G     S+ +  S+ED+AA V   P +FQLYV K
Sbjct:  75 VLAPVGLLGMQHGDGEIHACRAAQAAGIPFTQSTMSICSIEDIAASVEK-PFWFQLYVMK 133

Query: 144 DRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANFADM------ 197
           DR   + L+ RA  A   A+ LTVD   +G+R  DI+N   +PP  SL+   D       
Sbjct: 134 DRGFIKALIERAIAAKCSALVLTVDLQVIGQRHQDIKNGMTVPPEWSLSKLIDFATKPAW 193

Query: 198 ---------KDFAQVKGGAGAS----GLASYVASLIDASLNWNDIAWLKSITRLPILLKG 244
                    + F  + G    S     L++++ S  D SLNWNDI W++SI    ++LKG
Sbjct: 194 VSGVLQGKRRTFGNLAGHLKVSDDITSLSTWINSQFDTSLNWNDIDWIRSIWPGKLVLKG 253

Query: 245 VVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRG 304
           ++  EDA+ A + GA  I +SNHG RQLDG  ++I+ L E+  +V  R+ +  D G+R G
Sbjct: 254 ILDVEDAELAAKTGAQAIVVSNHGGRQLDGAPSSIEVLPEIVDAVGDRMEIMFDGGIRSG 313

Query: 305 TDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDI 362
            DV++ALALGA + +IGR   +GL   G+ GV + + +++ E    M LCG  ++ +I
Sbjct: 314 QDVMRALALGAKSCMIGRAYAYGLGAGGQAGVAKAIDIIQKELLTTMGLCGVNRIEEI 371

emb|CAG87560.1| unnamed protein product [Debaryomyces hansenii CBS767]
ref|XP_459365.1| unnamed protein product [Debaryomyces hansenii]
(558 aa)

Score: 243 bits (621), Expect: 6.13527e-63
Length: 365, Idn/Pos/Gap = 130/206/20 (35%/56%/5%)

Query:   9 PATQPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRV  68
           P     NL+++   AKA LP   + YY+ G+DDE T+R+N  AF R+ F P+VLID + +
Sbjct: 176 PLAAMFNLSDFEYVAKAILPKSAWSYYSGGSDDEVTMRENNNAFLRIFFNPKVLIDTADI 235

Query:  69 DITKQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAA 128
           D++ +++G     P   +  A  ++ HP+GEL+ A        +  +SS A+ S ++++ 
Sbjct: 236 DMSTEMLGTKTDAPFYCSAAAAAKLGHPDGELSIADGCGSENIIQMISSAASYSFDEISD 295

Query: 129 HV-PGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPP 187
                  ++FQLYV+KDR ++  ++   E+ G +AI +TVDTP  GRRE D+R +     
Sbjct: 296 FAKKSTSQWFQLYVHKDRTLSYEMIDACEKKGIKAIFVTVDTPLFGRREKDLRFK----- 350

Query: 188 HLSLANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVT 247
                   D  +  +  GG        ++ S  DA L W+DI   K  T LPI++KGV  
Sbjct: 351 ----VGQTDDDESDETSGGGD-----DFILSYRDAGLCWDDIDKFKKATNLPIVIKGVQR 401

Query: 248 AEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGR-----IPVFIDSGVR 302
            ED   A+++  DG+ +SNHG RQLD   A I+ L +V   +R +     I +++D G+R
Sbjct: 402 VEDVLLAIEHKVDGVVLSNHGGRQLDFARAPIEVLADVMPVLREKKLENEIEIYVDGGIR 461

Query: 303 RGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDI 362
           RG+DV+KAL LGA  V +GR  ++  +  G++GV +   LLKDE    M+L G  K+ D+
Sbjct: 462 RGSDVIKALCLGAKGVGLGRSFLYANSAYGKKGVVKACELLKDEIARDMKLLGVSKLEDL 521

Query: 363 RRDLV 367
           + +L+
Sbjct: 522 KPELL 526

ref|ZP_00047470.2| COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Lactobacillus gasseri]
(417 aa)

Score: 242 bits (617), Expect: 1.42502e-62
Length: 353, Idn/Pos/Gap = 134/205/11 (37%/58%/3%)

Query:  14 LNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQ  73
           +NL E    AK  +P   Y Y ASGA++E T R+N +AF   +  PR L  +    +  +
Sbjct:  25 VNLDELENEAKYVIPEAAYYYIASGAENEWTWRNNTQAFNHFQIVPRALTGMQDPKLNTE  84

Query:  74 VMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGL 133
            +G++L  P+M+ P A   +A+ E E+ TA+     G + G+S++A  S++DV + V   
Sbjct:  85 FLGMELKTPVMICPIACHGIANAEAEVDTAKGAKAAGALFGMSTYANKSVQDVQSAVGDS 144

Query: 134 PKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLAN 193
           P+F QLY+ K+    + ++  + +AGF    LTVD    G REA++R  F  P  L+   
Sbjct: 145 PRFMQLYLSKNWDFNKMVIEESVKAGFTGFFLTVDALVSGYREANLRTNFTYPVPLAF-- 202

Query: 194 FADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQR 253
                 F +  GG G     + + +    ++  +DI  +K I  +P+++KGV  AEDA  
Sbjct: 203 ------FNEWTGGKGEGQSVAQMYASSAQNIGPDDIRKIKEIADVPVIVKGVECAEDAML 256

Query: 254 ALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRG---RIPVFIDSGVRRGTDVVKA 310
           A+  GADGI +SNHG R++DG  ATID L E+A++V+     +P+ +D GVRRG+ V KA
Sbjct: 257 AIGAGADGIVVSNHGGREVDGAPATIDVLPEIAKAVKSCDHPVPIILDGGVRRGSHVFKA 316

Query: 311 LALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIR 363
           LALGAD V IGRP ++GLA+ G +GV  ++  L  E  + MQL GC+ + DI+
Sbjct: 317 LALGADLVGIGRPFLYGLALGGAQGVQSVIDQLNKELLIDMQLTGCKTIEDIK 369

gb|AAF62327.1| L-lactate dehydrogenase [Neisseria meningitidis MC58]
gb|AAB09666.1| lactate dehydrogenase
ref|NP_274393.1| L-lactate dehydrogenase [Neisseria meningitidis MC58]
(390 aa)

Score: 242 bits (617), Expect: 1.51073e-62
Length: 359, Idn/Pos/Gap = 130/204/20 (36%/56%/5%)

Query:  23 AKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGIDLSFP  82
           AK ++P M Y Y  SG+  E T R+N   F+ +RFR +VL+++    +  +++G D+  P
Sbjct:  18 AKRKMPRMFYDYIDSGSWTETTYRENTSDFKDIRFRQKVLVNMEGRSLETKMIGQDVKMP  77

Query:  83 LMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFFQLYVY 142
           + +APT    MAH +GE+  ARA  + G    LS+ +  S+EDVA +    P +FQLYV 
Sbjct:  78 VAIAPTGFTGMAHADGEILAARAAEKFGIPFTLSTMSICSIEDVAENTSA-PFWFQLYVM 136

Query: 143 KDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANFADM----- 197
           +DR   E L++RA+ A   A+ LT D   LG+R  DI+N    PP  ++AN  ++     
Sbjct: 137 RDREFMENLIKRAKDAKCSALVLTADLQVLGQRHKDIKNGLSAPPKPTIANLINLATKPE 196

Query: 198 ----------KDFAQVKGGAGASG----LASYVASLIDASLNWNDIAWLKSITRLPILLK 243
                     + F  + G A   G    L+S+ +   D  L+W+D+A +K +    +++K
Sbjct: 197 WCMKMLNTERRTFRNIVGHAKNVGDLSSLSSWTSEQFDPRLSWDDVARIKDLWGGKLIIK 256

Query: 244 GVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRR 303
           G++  EDA++A + GAD + +SNHG RQLD   + I  L ++  +V   I V++DSG+R 
Sbjct: 257 GIMEPEDAEKAAKSGADALIVSNHGGRQLDDTVSAIKALPDIVSAVGSDIEVWMDSGIRS 316

Query: 304 GTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDI 362
           G D++KA ALGA   +IGR  ++GL   GEEGV R L +L  E  ++M   G + + D+
Sbjct: 317 GQDILKAWALGAKGTMIGRAFLYGLGAYGEEGVTRALEILYKEMDISMAFTGHRDIQDV 375

emb|CAB84819.1| L-lactate dehydrogenase [Neisseria meningitidis Z2491]
ref|NP_284307.1| L-lactate dehydrogenase [Neisseria meningitidis Z2491]
pir||C81852 L-lactate dehydrogenase (cytochrome) (EC 1.1.2.3) NMA1592 [imported] - Neisseria meningitidis (strain Z2491 serogroup A)
(390 aa)

Score: 242 bits (617), Expect: 1.64219e-62
Length: 359, Idn/Pos/Gap = 130/204/20 (36%/56%/5%)

Query:  23 AKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGIDLSFP  82
           AK ++P M Y Y  SG+  E T R+N   F+ +RFR +VL+++    +  +++G D+  P
Sbjct:  18 AKRKMPRMFYDYIDSGSWTETTYRENTSDFKDIRFRQKVLVNMEGRSLETKMIGQDVKMP  77

Query:  83 LMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFFQLYVY 142
           + +APT    MAH +GE+  ARA  + G    LS+ +  S+EDVA +    P +FQLYV 
Sbjct:  78 VAIAPTGFTGMAHADGEILAARAAEKFGIPFTLSTMSICSIEDVAENTSA-PFWFQLYVM 136

Query: 143 KDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANFADM----- 197
           +DR   E L++RA+ A   A+ LT D   LG+R  DI+N    PP  ++AN  ++     
Sbjct: 137 RDREFMENLIKRAKDAKCSALVLTADLQVLGQRHKDIKNGLSAPPKPTIANLINLATKPE 196

Query: 198 ----------KDFAQVKGGAGASG----LASYVASLIDASLNWNDIAWLKSITRLPILLK 243
                     + F  + G A   G    L+S+ +   D  L+W+D+A +K +    +++K
Sbjct: 197 WCMKMLNTERRTFRNIVGHAKNVGDLSSLSSWTSEQFDPRLSWDDVARIKDLWGGKLIIK 256

Query: 244 GVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRR 303
           G++  EDA++A + GAD + +SNHG RQLD   + I  L ++  +V   I V++DSG+R 
Sbjct: 257 GIMEPEDAEKAAKSGADALVVSNHGGRQLDDTVSAIKALPDIVSAVGSDIEVWMDSGIRS 316

Query: 304 GTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDI 362
           G D++KA ALGA   +IGR  ++GL   GEEGV R L +L  E  ++M   G + + D+
Sbjct: 317 GQDILKAWALGAKGTMIGRAFLYGLGAYGEEGVTRALEILYKEMDISMAFTGHRDIQDV 375

pdb|1LTD|B Chain B, Flavocytochrome B2 (E.C.1.1.2.3) Complexed With Sulfite
pdb|1LTD|A Chain A, Flavocytochrome B2 (E.C.1.1.2.3) Complexed With Sulfite
(506 aa)

Score: 241 bits (616), Expect: 2.16274e-62
Length: 374, Idn/Pos/Gap = 138/220/18 (36%/58%/4%)

Query:   4 KPAVNPATQPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLI  63
           K  + P    +NL ++   A   L    + YY+SGA+DE T R+N  A+ R+ F+P++L+
Sbjct: 108 KSLLPPLDNIINLYDFEYLASQTLTKQAWAYYSSGANDEVTHRENHNAYHRIFFKPKILV 167

Query:  64 DVSRVDITKQVMGIDLSFPLMVAPTAMQRMAHP-EGELATARAVARIGTVMG--LSSWAT 120
           DV +VDI+  ++G  +  P  V+ TA+ ++ +P EGE   AR   +  T +   +S+ A+
Sbjct: 168 DVRKVDISTDMLGSHVDVPFYVSATALCKLGNPLEGEKDVARGCGQGVTKVPQMISTLAS 227

Query: 121 TSLEDVAAHVPGLPK--FFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREAD 178
            S E++    P   +  ++QLYV  DR IT+ LV+  E+ G +A+ +TVD P LG+RE D
Sbjct: 228 CSPEEIIEAAPSDKQIQWYQLYVNSDRKITDDLVKNVEKLGVKALFVTVDAPSLGQREKD 287

Query: 179 IRNQFQLPPHLSLANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRL 238
           ++ +F      + A    MK    V+   GAS     ++  ID SL W DI  LK  T+L
Sbjct: 288 MKLKFSN----TKAGPKAMKK-TNVEESQGAS---RALSKFIDPSLTWKDIEELKKKTKL 339

Query: 239 PILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEV-----AQSVRGRI 293
           PI++KGV   ED  +A + G  G+ +SNHG RQLD   A I+ L E       ++++ ++
Sbjct: 340 PIVIKGVQRTEDVIKAAEIGVSGVVLSNHGGRQLDFSRAPIEVLAETMPILEQRNLKDKL 399

Query: 294 PVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQL 353
            VF+D GVRRGTDV+KAL LGA  V +GRP ++  +  G  GV + + +L+DE +++M+L
Sbjct: 400 EVFVDGGVRRGTDVLKALCLGAKGVGLGRPFLYANSCYGRNGVEKAIEILRDEIEMSMRL 459

Query: 354 CGCQKVSDIRRDLV 367
            G   +++++ DL+
Sbjct: 460 LGVTSIAELKPDLL 473

emb|CAA86721.1| cytochrome b2 precursor [Saccharomyces cerevisiae]
emb|CAA26959.1| unnamed protein product [Saccharomyces cerevisiae]
sp|P00175|CYB2_YEAST Cytochrome b2, mitochondrial precursor (L-lactate dehydrogenase [Cytochrome]) (L-lactate ferricytochrome C oxidoreductase) (L-LCR)
ref|NP_013658.1| Cyb2p [Saccharomyces cerevisiae]
(591 aa)

Score: 241 bits (615), Expect: 2.70921e-62
Length: 374, Idn/Pos/Gap = 138/220/18 (36%/58%/4%)

Query:   4 KPAVNPATQPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLI  63
           K  + P    +NL ++   A   L    + YY+SGA+DE T R+N  A+ R+ F+P++L+
Sbjct: 193 KSLLPPLDNIINLYDFEYLASQTLTKQAWAYYSSGANDEVTHRENHNAYHRIFFKPKILV 252

Query:  64 DVSRVDITKQVMGIDLSFPLMVAPTAMQRMAHP-EGELATARAVARIGTVMG--LSSWAT 120
           DV +VDI+  ++G  +  P  V+ TA+ ++ +P EGE   AR   +  T +   +S+ A+
Sbjct: 253 DVRKVDISTDMLGSHVDVPFYVSATALCKLGNPLEGEKDVARGCGQGVTKVPQMISTLAS 312

Query: 121 TSLEDVAAHVPGLPK--FFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREAD 178
            S E++    P   +  ++QLYV  DR IT+ LV+  E+ G +A+ +TVD P LG+RE D
Sbjct: 313 CSPEEIIEAAPSDKQIQWYQLYVNSDRKITDDLVKNVEKLGVKALFVTVDAPSLGQREKD 372

Query: 179 IRNQFQLPPHLSLANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRL 238
           ++ +F      + A    MK    V+   GAS     ++  ID SL W DI  LK  T+L
Sbjct: 373 MKLKFSN----TKAGPKAMKK-TNVEESQGAS---RALSKFIDPSLTWKDIEELKKKTKL 424

Query: 239 PILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEV-----AQSVRGRI 293
           PI++KGV   ED  +A + G  G+ +SNHG RQLD   A I+ L E       ++++ ++
Sbjct: 425 PIVIKGVQRTEDVIKAAEIGVSGVVLSNHGGRQLDFSRAPIEVLAETMPILEQRNLKDKL 484

Query: 294 PVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQL 353
            VF+D GVRRGTDV+KAL LGA  V +GRP ++  +  G  GV + + +L+DE +++M+L
Sbjct: 485 EVFVDGGVRRGTDVLKALCLGAKGVGLGRPFLYANSCYGRNGVEKAIEILRDEIEMSMRL 544

Query: 354 CGCQKVSDIRRDLV 367
            G   +++++ DL+
Sbjct: 545 LGVTSIAELKPDLL 558

pdb|1KBI|B Chain B, Crystallographic Study Of The Recombinant Flavin-Binding Domain Of Baker's Yeast Flavocytochrome B2: Comparison With The Intact Wild-Type Enzyme
pdb|1KBI|A Chain A, Crystallographic Study Of The Recombinant Flavin-Binding Domain Of Baker's Yeast Flavocytochrome B2: Comparison With The Intact Wild-Type Enzyme
pdb|1FCB|B Chain B, Flavocytochrome b2 (E.C.1.1.2.3)
pdb|1FCB|A Chain A, Flavocytochrome b2 (E.C.1.1.2.3)
(511 aa)

Score: 241 bits (615), Expect: 2.7548e-62
Length: 374, Idn/Pos/Gap = 138/220/18 (36%/58%/4%)

Query:   4 KPAVNPATQPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLI  63
           K  + P    +NL ++   A   L    + YY+SGA+DE T R+N  A+ R+ F+P++L+
Sbjct: 113 KSLLPPLDNIINLYDFEYLASQTLTKQAWAYYSSGANDEVTHRENHNAYHRIFFKPKILV 172

Query:  64 DVSRVDITKQVMGIDLSFPLMVAPTAMQRMAHP-EGELATARAVARIGTVMG--LSSWAT 120
           DV +VDI+  ++G  +  P  V+ TA+ ++ +P EGE   AR   +  T +   +S+ A+
Sbjct: 173 DVRKVDISTDMLGSHVDVPFYVSATALCKLGNPLEGEKDVARGCGQGVTKVPQMISTLAS 232

Query: 121 TSLEDVAAHVPGLPK--FFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREAD 178
            S E++    P   +  ++QLYV  DR IT+ LV+  E+ G +A+ +TVD P LG+RE D
Sbjct: 233 CSPEEIIEAAPSDKQIQWYQLYVNSDRKITDDLVKNVEKLGVKALFVTVDAPSLGQREKD 292

Query: 179 IRNQFQLPPHLSLANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRL 238
           ++ +F      + A    MK    V+   GAS     ++  ID SL W DI  LK  T+L
Sbjct: 293 MKLKFSN----TKAGPKAMKK-TNVEESQGAS---RALSKFIDPSLTWKDIEELKKKTKL 344

Query: 239 PILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEV-----AQSVRGRI 293
           PI++KGV   ED  +A + G  G+ +SNHG RQLD   A I+ L E       ++++ ++
Sbjct: 345 PIVIKGVQRTEDVIKAAEIGVSGVVLSNHGGRQLDFSRAPIEVLAETMPILEQRNLKDKL 404

Query: 294 PVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQL 353
            VF+D GVRRGTDV+KAL LGA  V +GRP ++  +  G  GV + + +L+DE +++M+L
Sbjct: 405 EVFVDGGVRRGTDVLKALCLGAKGVGLGRPFLYANSCYGRNGVEKAIEILRDEIEMSMRL 464

Query: 354 CGCQKVSDIRRDLV 367
            G   +++++ DL+
Sbjct: 465 LGVTSIAELKPDLL 478

pdb|1SZE|B Chain B, L230a Mutant Flavocytochrome B2 With Benzoylformate
pdb|1SZE|A Chain A, L230a Mutant Flavocytochrome B2 With Benzoylformate
(511 aa)

Score: 241 bits (614), Expect: 3.65842e-62
Length: 374, Idn/Pos/Gap = 138/220/18 (36%/58%/4%)

Query:   4 KPAVNPATQPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLI  63
           K  + P    +NL ++   A   L    + YY+SGA+DE T R+N  A+ R+ F+P++L+
Sbjct: 113 KSLLPPLDNIINLYDFEYLASQTLTKQAWAYYSSGANDEVTHRENHNAYHRIFFKPKILV 172

Query:  64 DVSRVDITKQVMGIDLSFPLMVAPTAMQRMAHP-EGELATARAVARIGTVMG--LSSWAT 120
           DV +VDI+  ++G  +  P  V+ TA+ ++ +P EGE   AR   +  T +   +S+ A+
Sbjct: 173 DVRKVDISTDMLGSHVDVPFYVSATALCKLGNPLEGEKDVARGCGQGVTKVPQMISTAAS 232

Query: 121 TSLEDVAAHVPGLPK--FFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREAD 178
            S E++    P   +  ++QLYV  DR IT+ LV+  E+ G +A+ +TVD P LG+RE D
Sbjct: 233 CSPEEIIEAAPSDKQIQWYQLYVNSDRKITDDLVKNVEKLGVKALFVTVDAPSLGQREKD 292

Query: 179 IRNQFQLPPHLSLANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRL 238
           ++ +F      + A    MK    V+   GAS     ++  ID SL W DI  LK  T+L
Sbjct: 293 MKLKFSN----TKAGPKAMKK-TNVEESQGAS---RALSKFIDPSLTWKDIEELKKKTKL 344

Query: 239 PILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEV-----AQSVRGRI 293
           PI++KGV   ED  +A + G  G+ +SNHG RQLD   A I+ L E       ++++ ++
Sbjct: 345 PIVIKGVQRTEDVIKAAEIGVSGVVLSNHGGRQLDFSRAPIEVLAETMPILEQRNLKDKL 404

Query: 294 PVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQL 353
            VF+D GVRRGTDV+KAL LGA  V +GRP ++  +  G  GV + + +L+DE +++M+L
Sbjct: 405 EVFVDGGVRRGTDVLKALCLGAKGVGLGRPFLYANSCYGRNGVEKAIEILRDEIEMSMRL 464

Query: 354 CGCQKVSDIRRDLV 367
            G   +++++ DL+
Sbjct: 465 LGVTSIAELKPDLL 478

ref|ZP_00194824.2| COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Mesorhizobium sp. BNC1]
(391 aa)

Score: 240 bits (613), Expect: 4.01008e-62
Length: 375, Idn/Pos/Gap = 141/215/20 (37%/57%/5%)

Query:  14 LNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQ  73
           +N+ +Y   A+A LP M++ +    A D QT   N   F    FR       +  DI+  
Sbjct:  15 VNVQDYRKAARAVLPRMLFDFVDGSALDGQTASRNCAGFSDWWFRAHSFRSTAEPDISWS  74

Query:  74 VMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGL 133
             G   + P+++APT    +  P GE  TA A AR G VM +S+ +  S+E++AA   G 
Sbjct:  75 AFGQRHAAPVIIAPTGASGLLWPSGEAETAEAAARRGHVMQVSAGSLLSMEEIAAGGKGE 134

Query: 134 -PKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLA 192
             ++ QL++Y+DR +T   + RA+ AG+ AI +T D P  GRRE D+RN F +   L L+
Sbjct: 135 GERWLQLFLYRDRGLTREFLHRAKAAGYTAICVTTDAPVHGRRERDMRNGFTIDQRLRLS 194

Query: 193 NFAD------------------MKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKS 234
              D                  +K+FA  +     + +A+Y+AS++D  + W+DI+WL+S
Sbjct: 195 TLLDAAIHCRWWFRMRGSGRLTLKNFAG-RATGNMNDMAAYIASVLDPDVTWDDISWLRS 253

Query: 235 ITRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIP 294
               P+++KG++  +DA  A+  G DG+ ISNHG RQLDG  + ID L  V+ +V GR+P
Sbjct: 254 EWEGPLIIKGILHPDDACEAIARGCDGVQISNHGGRQLDGTLSAIDALPAVSDAVEGRVP 313

Query: 295 VFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLC 354
           +F+D G+ RGTD++KA+ALGA A +IGR  +WGLAV G +GV  +  +L  E + AM + 
Sbjct: 314 IFLDGGIERGTDILKAIALGATACVIGRAHLWGLAVAGGKGVEAVCDVLVAELRNAMVIG 373

Query: 355 GCQKVSDIRRDLVVR 369
           G + +SD+ R  V R
Sbjct: 374 GWKALSDLDRSAVTR 388

pdb|1KBJ|B Chain B, Crystallographic Study Of The Recombinant Flavin-Binding Domain Of Baker's Yeast Flavocytochrome B2: Comparison With The Intact Wild-Type Enzyme
pdb|1KBJ|A Chain A, Crystallographic Study Of The Recombinant Flavin-Binding Domain Of Baker's Yeast Flavocytochrome B2: Comparison With The Intact Wild-Type Enzyme
(412 aa)

Score: 240 bits (613), Expect: 4.65993e-62
Length: 374, Idn/Pos/Gap = 138/220/18 (36%/58%/4%)

Query:   4 KPAVNPATQPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLI  63
           K  + P    +NL ++   A   L    + YY+SGA+DE T R+N  A+ R+ F+P++L+
Sbjct:  14 KSLLPPLDNIINLYDFEYLASQTLTKQAWAYYSSGANDEVTHRENHNAYHRIFFKPKILV  73

Query:  64 DVSRVDITKQVMGIDLSFPLMVAPTAMQRMAHP-EGELATARAVARIGTVMG--LSSWAT 120
           DV +VDI+  ++G  +  P  V+ TA+ ++ +P EGE   AR   +  T +   +S+ A+
Sbjct:  74 DVRKVDISTDMLGSHVDVPFYVSATALCKLGNPLEGEKDVARGCGQGVTKVPQMISTLAS 133

Query: 121 TSLEDVAAHVPGLPK--FFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREAD 178
            S E++    P   +  ++QLYV  DR IT+ LV+  E+ G +A+ +TVD P LG+RE D
Sbjct: 134 CSPEEIIEAAPSDKQIQWYQLYVNSDRKITDDLVKNVEKLGVKALFVTVDAPSLGQREKD 193

Query: 179 IRNQFQLPPHLSLANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRL 238
           ++ +F      + A    MK    V+   GAS     ++  ID SL W DI  LK  T+L
Sbjct: 194 MKLKFSN----TKAGPKAMKK-TNVEESQGAS---RALSKFIDPSLTWKDIEELKKKTKL 245

Query: 239 PILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEV-----AQSVRGRI 293
           PI++KGV   ED  +A + G  G+ +SNHG RQLD   A I+ L E       ++++ ++
Sbjct: 246 PIVIKGVQRTEDVIKAAEIGVSGVVLSNHGGRQLDFSRAPIEVLAETMPILEQRNLKDKL 305

Query: 294 PVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQL 353
            VF+D GVRRGTDV+KAL LGA  V +GRP ++  +  G  GV + + +L+DE +++M+L
Sbjct: 306 EVFVDGGVRRGTDVLKALCLGAKGVGLGRPFLYANSCYGRNGVEKAIEILRDEIEMSMRL 365

Query: 354 CGCQKVSDIRRDLV 367
            G   +++++ DL+
Sbjct: 366 LGVTSIAELKPDLL 379

ref|ZP_00376686.1| hypothetical protein ELI1927 [Erythrobacter litoralis HTCC2594]
gb|EAL75416.1| hypothetical protein ELI1927 [Erythrobacter litoralis HTCC2594]
(384 aa)

Score: 240 bits (613), Expect: 4.89915e-62
Length: 371, Idn/Pos/Gap = 143/209/21 (38%/56%/5%)

Query:  15 NLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQV  74
           N+ ++   AK RLP  V+ Y    ADDE T   N  A+  +   P VL  V+ +D +  +
Sbjct:   8 NIEDFRRLAKTRLPWPVFDYIDGAADDELTKARNTAAYDDVDLVPDVLAGVAEIDTSCTI  67

Query:  75 MGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLP 134
           MG + + PL+++PTA+QR  H +GE A A+A  + G   G+SS AT S+E++AA   G P
Sbjct:  68 MGRESALPLLLSPTAVQRAFHWQGETAVAKAAEKFGLWFGISSLATRSIEEIAALTQG-P 126

Query: 135 KFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLS---L 191
           K FQLYV+KD+ + + ++ R + A F A+ALTVDT   G+RE  +R+ F  PP  S   +
Sbjct: 127 KLFQLYVHKDKGLNQSMIERCQAAQFDALALTVDTIVSGKRERCLRSGFTTPPKFSPSAV 186

Query: 192 ANFADMK-----------------DFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKS 234
            ++A                    D    +G   A  +A Y  +++D S+NW+  A ++ 
Sbjct: 187 WSYATRPRWTLDYLFRERFRLPNLDTHVAEGSREAVSIAEYFNTMLDTSMNWDTAAKIRQ 246

Query: 235 ITRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIP 294
                  LKGV++A DA+RA++ GAD I ISNHG RQLDG  A  D L E+ ++V G I 
Sbjct: 247 DWGGTFCLKGVMSAGDARRAVEIGADAIMISNHGGRQLDGSRAPFDQLGEIVKAVGGEIE 306

Query: 295 VFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLC 354
           +  D GVRRGT  +KA++ GA A   GR  ++ LA  G+ GV R + +LKDE +  M+L 
Sbjct: 307 IICDGGVRRGTHALKAVSAGATAASGGRLYLYALAAAGQPGVERAIGILKDEIERGMRLM 366

Query: 355 GCQKVSDIRRD 365
           G   V  +  D
Sbjct: 367 GVTSVDQLTAD 377

gb|EAA74089.1| hypothetical protein FG04988.1 [Gibberella zeae PH-1]
ref|XP_385164.1| hypothetical protein FG04988.1 [Gibberella zeae PH-1]
(412 aa)

Score: 240 bits (613), Expect: 5.06542e-62
Length: 375, Idn/Pos/Gap = 148/216/19 (39%/57%/5%)

Query:   2 VEKPAVNPA-TQPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPR  60
           ++ P+  PA  Q L+  ++ L A+  L    + +Y+S A D  T+ +N E  RR+  RPR
Sbjct:  20 IQLPSNVPALDQILSANDFALAAQKALIPKAWAFYSSAATDLVTVTNNRELIRRVMLRPR  79

Query:  61 VLIDVSRVDITKQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWAT 120
           +L +VS+V+I ++++G+    P  + P AM  +AHP+GEL  +RA A  G    +SS A+
Sbjct:  80 ILRNVSQVNIGRKILGLQSKAPFFMCPAAMATLAHPDGELGWSRAAASEGIFEIISSNAS 139

Query: 121 TSLED-VAAHVPGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADI 179
            SL   + A  PG P F QLYV  +R  T +L+ RA   G +AI +TVD P  G+READ 
Sbjct: 140 YSLPSIIGAAPPGHPFFLQLYVNSNRPKTVQLLNRAHSLGIKAIFVTVDAPVPGKREADE 199

Query: 180 RNQFQLPPHLSLANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLP 239
           R      P   +   ++M      K G G SGL   +   ID SL+W+D+ W++  + +P
Sbjct: 200 R-----APQAVVIK-SEMSGSESSKDGKG-SGLGRLMGQYIDKSLSWDDLEWIRRESSVP 252

Query: 240 ILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIP----- 294
           I+LKGV T ED + A+ YG DG+ +SNHG R LDG++A    L  +   VR R P     
Sbjct: 253 IVLKGVQTVEDVKLAVDYGVDGVMLSNHGGRSLDGISAQASIL--ILLEVRKRFPEAFDH 310

Query: 295 --VFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQ 352
             +FID G  RG+D++KA+ALGA AV I RP ++ L V G++GV  L  +LKDE + +M+
Sbjct: 311 LEIFIDGGFERGSDILKAIALGATAVGIARPFLYSL-VYGQKGVEHLSQILKDELETSMR 369

Query: 353 LCGCQKVSDIRRDLV 367
           L G   +      LV
Sbjct: 370 LAGLTSLDQATPSLV 384

gb|AAV94118.1| L-lactate dehydrogenase, putative [Silicibacter pomeroyi DSS-3]
ref|YP_166066.1| L-lactate dehydrogenase, putative [Silicibacter pomeroyi DSS-3]
(387 aa)

Score: 240 bits (612), Expect: 6.72697e-62
Length: 379, Idn/Pos/Gap = 140/211/21 (36%/55%/5%)

Query:  15 NLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQV  74
           N+ +     + R+P M Y Y  SG+  EQT R+N   F  +R R RV +D+S      Q+
Sbjct:   6 NIEDLKRIYERRVPRMFYDYAESGSWTEQTFRENSSDFDLIRLRQRVAVDMSGRSTASQM  65

Query:  75 MGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLP 134
           +G D++ P+ +AP  +  M H +GE+  ARA    G    LS+ +  S+E+VA    G P
Sbjct:  66 VGQDVAMPVALAPVGLTGMQHADGEIKAARAANEFGVPFTLSTMSINSIEEVA-EATGRP 124

Query: 135 KFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLS---L 191
            +FQLY  +D   T RL++RA+ A   A+ +T+D   LG+R  D++N    PP L+   +
Sbjct: 125 FWFQLYTMRDTDYTSRLIQRAKAANCSALVITLDLQILGQRHKDLKNGLSAPPKLTPRTI 184

Query: 192 ANF------------ADMKDFA----QVKGGAGASGLASYVASLIDASLNWNDIAWLKSI 235
           AN             A  ++F      V G +  + L ++ A   D +L+W  +A L   
Sbjct: 185 ANLMTKWAWGIEMLGAKRRNFGNIVGHVHGVSDTANLGAWTAEQFDPTLDWGKVAKLMEQ 244

Query: 236 TRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPV 295
               ++LKG++ AEDA+ A + GAD I +SNHG RQLDG  ++I  L E+  +V G I V
Sbjct: 245 WDGKVILKGILDAEDAKMAAKLGADAIVVSNHGGRQLDGALSSIRVLPEIMDAVGGDIEV 304

Query: 296 FIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCG 355
            +DSG+R G DV+KALALGA   +IGR  V+GL   G++GV   L +++ E    M LCG
Sbjct: 305 HLDSGIRSGQDVLKALALGAKGTMIGRAFVYGLGAMGQKGVTTALEVIRKELDTTMALCG 364

Query: 356 CQKVSDI-RRDLVVRDAFA 373
            + V+D+ R +L+V + F 
Sbjct: 365 ERNVADLGRHNLLVPEDFG 383

pdb|1LDC|B Chain B, L-Lactate Dehydrogenase: Cytochrome C Oxidoreductase (Flavocytochrome B2) (E.C.1.1.2.3) Mutant With Tyr 143 Replaced By Phe (Y143f) Complexed With Pyruvate
pdb|1LDC|A Chain A, L-Lactate Dehydrogenase: Cytochrome C Oxidoreductase (Flavocytochrome B2) (E.C.1.1.2.3) Mutant With Tyr 143 Replaced By Phe (Y143f) Complexed With Pyruvate
pdb|1LCO|B Chain B, Mol_id: 1; Molecule: L-Lactate Dehydrogenase; Chain: A, B; Synonym: Cytochrome C Oxidoreductase, Flavocytochrome B2; Ec: 1.1.2.3; Engineered: Yes; Mutation: Tyr 143 Phe; Heterogen: Phenyl-Pyruvate
pdb|1LCO|A Chain A, Mol_id: 1; Molecule: L-Lactate Dehydrogenase; Chain: A, B; Synonym: Cytochrome C Oxidoreductase, Flavocytochrome B2; Ec: 1.1.2.3; Engineered: Yes; Mutation: Tyr 143 Phe; Heterogen: Phenyl-Pyruvate
(511 aa)

Score: 239 bits (611), Expect: 8.08239e-62
Length: 374, Idn/Pos/Gap = 137/220/18 (36%/58%/4%)

Query:   4 KPAVNPATQPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLI  63
           K  + P    +NL ++   A   L    + +Y+SGA+DE T R+N  A+ R+ F+P++L+
Sbjct: 113 KSLLPPLDNIINLYDFEYLASQTLTKQAWAFYSSGANDEVTHRENHNAYHRIFFKPKILV 172

Query:  64 DVSRVDITKQVMGIDLSFPLMVAPTAMQRMAHP-EGELATARAVARIGTVMG--LSSWAT 120
           DV +VDI+  ++G  +  P  V+ TA+ ++ +P EGE   AR   +  T +   +S+ A+
Sbjct: 173 DVRKVDISTDMLGSHVDVPFYVSATALCKLGNPLEGEKDVARGCGQGVTKVPQMISTLAS 232

Query: 121 TSLEDVAAHVPGLPK--FFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREAD 178
            S E++    P   +  ++QLYV  DR IT+ LV+  E+ G +A+ +TVD P LG+RE D
Sbjct: 233 CSPEEIIEAAPSDKQIQWYQLYVNSDRKITDDLVKNVEKLGVKALFVTVDAPSLGQREKD 292

Query: 179 IRNQFQLPPHLSLANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRL 238
           ++ +F      + A    MK    V+   GAS     ++  ID SL W DI  LK  T+L
Sbjct: 293 MKLKFSN----TKAGPKAMKK-TNVEESQGAS---RALSKFIDPSLTWKDIEELKKKTKL 344

Query: 239 PILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEV-----AQSVRGRI 293
           PI++KGV   ED  +A + G  G+ +SNHG RQLD   A I+ L E       ++++ ++
Sbjct: 345 PIVIKGVQRTEDVIKAAEIGVSGVVLSNHGGRQLDFSRAPIEVLAETMPILEQRNLKDKL 404

Query: 294 PVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQL 353
            VF+D GVRRGTDV+KAL LGA  V +GRP ++  +  G  GV + + +L+DE +++M+L
Sbjct: 405 EVFVDGGVRRGTDVLKALCLGAKGVGLGRPFLYANSCYGRNGVEKAIEILRDEIEMSMRL 464

Query: 354 CGCQKVSDIRRDLV 367
            G   +++++ DL+
Sbjct: 465 LGVTSIAELKPDLL 478

pdb|1SZG|B Chain B, A198g:l230a Flavocytochrome B2 With Sulfite Bound
pdb|1SZG|A Chain A, A198g:l230a Flavocytochrome B2 With Sulfite Bound
pdb|1SZF|B Chain B, A198g:l230a Mutant Flavocytochrome B2 With Pyruvate Bound
pdb|1SZF|A Chain A, A198g:l230a Mutant Flavocytochrome B2 With Pyruvate Bound
(511 aa)

Score: 239 bits (610), Expect: 9.15997e-62
Length: 374, Idn/Pos/Gap = 137/219/18 (36%/58%/4%)

Query:   4 KPAVNPATQPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLI  63
           K  + P    +NL ++   A   L    + YY+SGA+DE T R+N  A+ R+ F+P++L+
Sbjct: 113 KSLLPPLDNIINLYDFEYLASQTLTKQAWAYYSSGANDEVTHRENHNAYHRIFFKPKILV 172

Query:  64 DVSRVDITKQVMGIDLSFPLMVAPTAMQRMAHP-EGELATARAVARIGTVMG--LSSWAT 120
           DV +VDI+  ++G  +  P  V+ T + ++ +P EGE   AR   +  T +   +S+ A+
Sbjct: 173 DVRKVDISTDMLGSHVDVPFYVSATGLCKLGNPLEGEKDVARGCGQGVTKVPQMISTAAS 232

Query: 121 TSLEDVAAHVPGLPK--FFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREAD 178
            S E++    P   +  ++QLYV  DR IT+ LV+  E+ G +A+ +TVD P LG+RE D
Sbjct: 233 CSPEEIIEAAPSDKQIQWYQLYVNSDRKITDDLVKNVEKLGVKALFVTVDAPSLGQREKD 292

Query: 179 IRNQFQLPPHLSLANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRL 238
           ++ +F      + A    MK    V+   GAS     ++  ID SL W DI  LK  T+L
Sbjct: 293 MKLKFSN----TKAGPKAMKK-TNVEESQGAS---RALSKFIDPSLTWKDIEELKKKTKL 344

Query: 239 PILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEV-----AQSVRGRI 293
           PI++KGV   ED  +A + G  G+ +SNHG RQLD   A I+ L E       ++++ ++
Sbjct: 345 PIVIKGVQRTEDVIKAAEIGVSGVVLSNHGGRQLDFSRAPIEVLAETMPILEQRNLKDKL 404

Query: 294 PVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQL 353
            VF+D GVRRGTDV+KAL LGA  V +GRP ++  +  G  GV + + +L+DE +++M+L
Sbjct: 405 EVFVDGGVRRGTDVLKALCLGAKGVGLGRPFLYANSCYGRNGVEKAIEILRDEIEMSMRL 464

Query: 354 CGCQKVSDIRRDLV 367
            G   +++++ DL+
Sbjct: 465 LGVTSIAELKPDLL 478

gb|EAL17855.1| hypothetical protein CNBL1170 [Cryptococcus neoformans var. neoformans B-3501A]
(569 aa)

Score: 239 bits (610), Expect: 9.15997e-62
Length: 371, Idn/Pos/Gap = 144/208/23 (38%/56%/6%)

Query:  14 LNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQ  73
           + L ++   AKA L +  + Y +SGA D+ TL  N +AF  + FRPRVL+DV   D   Q
Sbjct: 198 IGLPDFDAAAKANLTSKAWAYMSSGATDQYTLDLNRKAFNSILFRPRVLVDVEIADTRTQ 257

Query:  74 VMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDV--AAHVP 131
           ++G D S P+ ++P  M ++AHPEGE   A+A  +   +  +S+ A+  L  +  +A  P
Sbjct: 258 MLGQDTSLPIFISPAGMAKLAHPEGECLLAKAAGQSNIIQMISTNASAPLPSIISSATSP 317

Query: 132 GLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSL 191
             P F QLYV ++R  TE L+ +    G +AI +TVD P  G+READ R++         
Sbjct: 318 SQPFFMQLYVDRNRPKTESLLGKINSLGLKAIFVTVDAPAPGKREADERSR--------- 368

Query: 192 ANFADMKDFAQVKGGAGAS-----GLASYVASLIDASLNWNDIAWLKSITRLPILLKGVV 246
              A+++  + + GG   S     G+   V   ID  L+W DI WL+  T+LPI LKGV 
Sbjct: 369 ---AEVEVASGISGGKIGSDNKGGGIGRSVGGFIDPKLSWKDIEWLRQHTKLPIGLKGVQ 425

Query: 247 TAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEE---VAQSVRGRIPVFIDSGVRR 303
           TAEDA +A + G D I++SNHG R LDG    +  L E   +   +  +  V+ID G RR
Sbjct: 426 TAEDAMKAAKMGVDAIYLSNHGGRALDGSPPAMYTLLEMNKICPEIFKKCEVYIDGGCRR 485

Query: 304 GTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIR 363
           GTDVVKAL LGA  V +GRP ++ L   GEEGV   + +++DE +  M+L G  K+  + 
Sbjct: 486 GTDVVKALCLGAKGVGMGRPFLYSLTY-GEEGVVHAIEIMRDEIETTMRLLGVTKLDQLG 544

Query: 364 RDLVVRDAFAP 374
             L+   A  P
Sbjct: 545 PHLLNTKALDP 555

gb|AAW45006.1| cytochrome b2, mitochondrial precursor, putative [Cryptococcus neoformans var. neoformans JEC21]
ref|XP_572313.1| cytochrome b2, mitochondrial precursor, putative [Cryptococcus neoformans var. neoformans JEC21]
(593 aa)

Score: 239 bits (610), Expect: 9.23672e-62
Length: 371, Idn/Pos/Gap = 144/208/23 (38%/56%/6%)

Query:  14 LNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQ  73
           + L ++   AKA L +  + Y +SGA D+ TL  N +AF  + FRPRVL+DV   D   Q
Sbjct: 222 IGLPDFDAAAKANLTSKAWAYMSSGATDQYTLDLNRKAFNSILFRPRVLVDVEIADTRTQ 281

Query:  74 VMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDV--AAHVP 131
           ++G D S P+ ++P  M ++AHPEGE   A+A  +   +  +S+ A+  L  +  +A  P
Sbjct: 282 MLGQDTSLPIFISPAGMAKLAHPEGECLLAKAAGQSNIIQMISTNASAPLPSIISSATSP 341

Query: 132 GLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSL 191
             P F QLYV ++R  TE L+ +    G +AI +TVD P  G+READ R++         
Sbjct: 342 SQPFFMQLYVDRNRPKTESLLGKINSLGLKAIFVTVDAPAPGKREADERSR--------- 392

Query: 192 ANFADMKDFAQVKGGAGAS-----GLASYVASLIDASLNWNDIAWLKSITRLPILLKGVV 246
              A+++  + + GG   S     G+   V   ID  L+W DI WL+  T+LPI LKGV 
Sbjct: 393 ---AEVEVASGISGGKIGSDNKGGGIGRSVGGFIDPKLSWKDIEWLRQHTKLPIGLKGVQ 449

Query: 247 TAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEE---VAQSVRGRIPVFIDSGVRR 303
           TAEDA +A + G D I++SNHG R LDG    +  L E   +   +  +  V+ID G RR
Sbjct: 450 TAEDAMKAAKMGVDAIYLSNHGGRALDGSPPAMYTLLEMNKICPEIFKKCEVYIDGGCRR 509

Query: 304 GTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIR 363
           GTDVVKAL LGA  V +GRP ++ L   GEEGV   + +++DE +  M+L G  K+  + 
Sbjct: 510 GTDVVKALCLGAKGVGMGRPFLYSLTY-GEEGVVHAIEIMRDEIETTMRLLGVTKLDQLG 568

Query: 364 RDLVVRDAFAP 374
             L+   A  P
Sbjct: 569 PHLLNTKALDP 579

emb|CAC49543.1| putative L-lactate dehydrogenase (cytochrome) protein [Sinorhizobium meliloti 1021]
ref|NP_437683.1| putative L-lactate dehydrogenase (cytochrome) protein [Sinorhizobium meliloti 1021]
pir||G95984 probable L-lactate dehydrogenase (cytochrome) (EC 1.1.2.3) [imported] - Sinorhizobium meliloti (strain 1021) magaplasmid pSymB
(378 aa)

Score: 239 bits (610), Expect: 1.03812e-61
Length: 376, Idn/Pos/Gap = 134/210/20 (35%/55%/5%)

Query:  11 TQPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDI  70
           TQ L + +    A+ R+P + + Y  SGA  E T R NEE F  ++ R RVL+D+S   +
Sbjct:   2 TQILEIRDLKALARRRVPKLFFDYADSGAWTEGTYRANEEDFAGIKLRQRVLVDMSDRSL  61

Query:  71 TKQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHV 130
              ++G  +S P+ +APT +  M H +GE+  A+A    G    LS+ +  S+EDVA+ V
Sbjct:  62 ETTMIGQKVSMPVALAPTGLTGMQHADGEMLAAQAAEAFGVPFTLSTMSICSIEDVAS-V 120

Query: 131 PGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLS 190
              P +FQLYV ++R     L+ RA+ A   A+ +T+D   LG+R  D+RN    PP L+
Sbjct: 121 TTKPFWFQLYVMREREFVLDLIDRAKAAKCSALVMTLDLQILGQRHKDLRNGLSAPPRLT 180

Query: 191 LANF---------------ADMKDFAQVKGGAGA----SGLASYVASLIDASLNWNDIAW 231
             +                 + + F  + G A +    S L ++     D  L+W D+ W
Sbjct: 181 PKHLWMMATRPGWCMKMLGTNRRTFRNIVGHAKSVADLSSLQAWTNEQFDPQLSWKDVEW 240

Query: 232 LKSITRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRG 291
           +K     P++LKG++  EDA+ A + GAD I +SNHG RQLDG  ++I  L  + ++V  
Sbjct: 241 IKERWGGPLILKGILDPEDAKMAAKTGADAIIVSNHGGRQLDGAHSSISMLPRIVEAVGD 300

Query: 292 RIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAM 351
           +I V +D G+R G DV+KA+ALGA    IGRP ++GL   G+EGV   L +++ E    M
Sbjct: 301 QIEVHLDGGIRSGQDVLKAIALGAKGTYIGRPFLYGLGALGKEGVTLALDIIRKEMDTTM 360

Query: 352 QLCGCQKVSDIRRDLV 367
            LCG ++++++ RD++
Sbjct: 361 ALCGKRRITEVGRDII 376

emb|CAG61646.1| unnamed protein product [Candida glabrata CBS138]
ref|XP_448683.1| unnamed protein product [Candida glabrata]
(593 aa)

Score: 239 bits (610), Expect: 1.13791e-61
Length: 370, Idn/Pos/Gap = 135/213/20 (36%/57%/5%)

Query:   9 PATQPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRV  68
           P +  +NL ++   A   L    + YY+S +DDE + R+N  A+ R+ F P+VL+DVS+V
Sbjct: 197 PLSSIMNLYDFEYLASQILSKQAWAYYSSASDDEVSYRENHNAYHRIFFNPKVLVDVSKV 256

Query:  69 DITKQVMGIDLSFPLMVAPTAMQRMAHP-EGELATARAVAR--IGTVMGLSSWATTSLED 125
           D + +++G  +  P  V  TA+ ++ +P EGE   AR   +    T   +S+ A+ S+++
Sbjct: 257 DTSTEMLGHKVDVPFYVTATALCKLGNPKEGEKDIARGCGQGPNKTPQMISTLASCSVDE 316

Query: 126 VAAHVPGLPK--FFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQF 183
           +    P   +  ++QLYV  DR ITE L++  E  G +AI +TVD P LG RE D + +F
Sbjct: 317 IVNAAPSKDQVIWYQLYVNSDRKITENLIKHVEDLGVKAIFVTVDAPSLGSREKDKKVKF 376

Query: 184 QLPPHLSLANFADMKDFAQVKGGAGAS-GLASYVASLIDASLNWNDIAWLKSITRLPILL 242
               + +++    MK     K   G S G A  ++  ID SL+W DI  L+  T+LPI++
Sbjct: 377 ----NNTMSGPKSMK-----KSDVGESEGAAQTLSKFIDPSLSWQDIKILRKKTKLPIVI 427

Query: 243 KGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGR-----IPVFI 297
           KGV   +D  +A + G +G+ +SNHG RQLD   A I+ L E    ++ +       VF+
Sbjct: 428 KGVQRVQDVVKAAEIGCNGVVLSNHGGRQLDFARAPIEVLAETMPVLKEKKLDKNFEVFV 487

Query: 298 DSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQ 357
           D GVRRGTDV+KAL LGA  V +GRP ++  +  G++GV + + LLK E ++ M+L G  
Sbjct: 488 DGGVRRGTDVIKALCLGASGVGLGRPFLYANSCYGKDGVQKAIDLLKTEIEMNMRLLGVT 547

Query: 358 KVSDIRRDLV 367
            + D+  +L+
Sbjct: 548 SIKDMNPELL 557

ref|YP_059684.1| L-lactate oxidase [Streptococcus pyogenes MGAS10394]
gb|AAT86501.1| L-lactate oxidase [Streptococcus pyogenes MGAS10394]
(395 aa)

Score: 239 bits (609), Expect: 1.21646e-61
Length: 350, Idn/Pos/Gap = 130/193/9 (37%/55%/2%)

Query:  14 LNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQ  73
           +N+ +    A+  +P   +GY ASGA D  TL +N  +F      P  L  V        
Sbjct:  32 INVFDLEKMAQQVIPKGAFGYIASGAGDTFTLHENIRSFNHKLIVPHSLKGVENPSTEIT  91

Query:  74 VMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGL 133
             G  L+ PL++AP A  ++A+ +GE+A+A+ +   G++   SS++TT L +++A + G 
Sbjct:  92 FDGDHLTSPLILAPVAAHKLANEQGEVASAKGLKEFGSIYTTSSYSTTDLPEISAALGGT 151

Query: 134 PKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLAN 193
           P +FQ Y  KD  I   ++ R +  G +AI LT D    G RE D RN F  P  + +  
Sbjct: 152 PHWFQFYYSKDDGINRNIMDRVKAQGCKAIVLTADATVGGNREVDRRNGFVFPVGMPIVQ 211

Query: 194 FADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQR 253
                    +  GAG +    YV      +L   DI ++ + + LP+ +KG   AED  R
Sbjct: 212 -------EYLPDGAGKT--MDYVYKSAKQALTSKDIEYIATYSGLPVYVKGPQCAEDTLR 262

Query: 254 ALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALAL 313
           AL  GA GIW++NHG RQLDG  A  D L+EVA++V  ++P+  DSG+RRG  + KALA 
Sbjct: 263 ALDAGASGIWVTNHGGRQLDGGPAAFDSLQEVAEAVDHKVPIVFDSGIRRGQHIFKALAS 322

Query: 314 GADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIR 363
           GAD V +GRP ++GLA+ G  G  ++   L DE K+ MQL G Q + D++
Sbjct: 323 GADLVALGRPAIYGLAMGGSIGTRQVFEKLNDELKMVMQLAGTQTIQDVK 372

gb|AAL97194.1| putative lactate oxidase [Streptococcus pyogenes MGAS8232]
ref|NP_606695.1| putative lactate oxidase [Streptococcus pyogenes MGAS8232]
(393 aa)

Score: 239 bits (609), Expect: 1.34457e-61
Length: 350, Idn/Pos/Gap = 130/193/9 (37%/55%/2%)

Query:  14 LNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQ  73
           +N+ +    A+  +P   +GY ASGA D  TL +N  +F      P  L  V        
Sbjct:  30 INVFDLEKMAQQVIPKGAFGYIASGAGDTFTLHENIRSFNHKLIVPHSLKGVENPSTEIT  89

Query:  74 VMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGL 133
             G  L+ PL++AP A  ++A+ +GE+A+A+ +   G++   SS++TT L +++A + G 
Sbjct:  90 FDGDHLTSPLILAPVAAHKLANEQGEVASAKGLKEFGSIYTTSSYSTTDLPEISAALGGT 149

Query: 134 PKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLAN 193
           P +FQ Y  KD  I   ++ R +  G +AI LT D    G RE D RN F  P  + +  
Sbjct: 150 PHWFQFYYSKDDGINRNIMDRVKAQGCKAIVLTADATVGGNREVDRRNGFVFPVGMPIVQ 209

Query: 194 FADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQR 253
                    +  GAG +    YV      +L   DI ++ + + LP+ +KG   AED  R
Sbjct: 210 -------EYLPDGAGKT--MDYVYKSAKQALTSKDIEYIATYSGLPVYVKGPQCAEDTLR 260

Query: 254 ALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALAL 313
           AL  GA GIW++NHG RQLDG  A  D L+EVA++V  ++P+  DSG+RRG  + KALA 
Sbjct: 261 ALDAGASGIWVTNHGGRQLDGGPAAFDSLQEVAEAVDQKVPIVFDSGIRRGQHIFKALAS 320

Query: 314 GADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIR 363
           GAD V +GRP ++GLA+ G  G  ++   L DE K+ MQL G Q + D++
Sbjct: 321 GADLVALGRPAIYGLAMGGSIGTRQVFEKLNDELKMVMQLAGTQTIQDVK 370

gb|EAA64695.1| hypothetical protein AN2590.2 [Aspergillus nidulans FGSC A4]
ref|XP_406727.1| hypothetical protein AN2590.2 [Aspergillus nidulans FGSC A4]
(488 aa)

Score: 239 bits (609), Expect: 1.35583e-61
Length: 362, Idn/Pos/Gap = 134/203/14 (37%/56%/3%)

Query:   9 PATQPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRV  68
           P    +N  ++   A        Y +Y++   D  T   NE   +R+ FRPRV+ DV+ V
Sbjct: 112 PLASLINSYDFEKAAAVSASEKAYTFYSTADTDCWTRDANESMLKRIWFRPRVMRDVASV 171

Query:  69 DITKQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAA 128
           D +  ++GI +S PL + P  +  + +P+ E A ARA    G V  +S+ +   L D+  
Sbjct: 172 DTSTSMLGIQMSIPLFICPAGVGSLINPDAEKALARAAESTGIVEIISTNSAHPLADIVE 231

Query: 129 HVPGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPH 188
             PG P  FQLY+ K R  ++ L+ +AE  G RAI LTVD+   G+RE+D R        
Sbjct: 232 QAPGYPFLFQLYLNKQRQKSKELLLKAESLGCRAIFLTVDSAGRGKRESDER-------- 283

Query: 189 LSLANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTA 248
             L +   ++D    K     +GL   + S ID  + W D+AW++S+T+LPI+LKG+ +A
Sbjct: 284 --LKSDEMLRDPVTGKLMKAGAGLTRIMGSFIDQGMTWKDLAWIRSVTKLPIILKGITSA 341

Query: 249 EDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQS---VRGRIPVFIDSGVRRGT 305
           EDA+ A+QY  DGI +SNHG R LD    TI  L E+ ++   +  ++ +++D G RRG 
Sbjct: 342 EDAKIAMQYKVDGILLSNHGGRNLDYSPPTILLLLELHKNCPEIFDKMEIYVDGGFRRGA 401

Query: 306 DVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRD 365
           D++KAL LGA AV +GR  ++ L   G EGV  L+ LLK E +  M+L G + +S++   
Sbjct: 402 DIIKALCLGAKAVGMGRSFLYALNY-GTEGVEHLIQLLKAEMEAVMKLIGIKDLSEVYPG 460

Query: 366 LV 367
           LV
Sbjct: 461 LV 462

gb|EAA71695.1| hypothetical protein FG03709.1 [Gibberella zeae PH-1]
ref|XP_383885.1| hypothetical protein FG03709.1 [Gibberella zeae PH-1]
(431 aa)

Score: 238 bits (608), Expect: 1.56245e-61
Length: 365, Idn/Pos/Gap = 129/216/17 (35%/59%/4%)

Query:   9 PATQPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRV  68
           P  +  +  ++   A+  +    + YY++G+DDE TLR+N ++F+++RFRP+V+++V  V
Sbjct:  68 PKAKEGSQKDFESVAQNLMKKTSWNYYSTGSDDEFTLRENSQSFQQIRFRPKVMVNVEHV 127

Query:  69 DITKQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVA- 127
           DI+   +G   S P+ ++ TA  ++A PEGE+  ARA  +   +  +  +++  LED+  
Sbjct: 128 DISTNFLGSRTSAPIYISATAHAKIADPEGEVTLARASNKHDIIQMIPLYSSFPLEDITK 187

Query: 128 AHVPGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPP 187
           A  P   ++FQ+YV KDR +T R +  AE+ G +A+ +TVD P LG RE  +R Q     
Sbjct: 188 AREPDRTQWFQVYVKKDRNVTRRAIENAEKHGCKALCITVDNPHLGSRERVLRLQ----- 242

Query: 188 HLSLANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVT 247
                + AD            A+ L   +  +++++L+W+DI+W +SIT++ I+LKGV  
Sbjct: 243 ----QSEADEDGDDDEFEDLPATELDPSL--IMNSTLSWDDISWFRSITKMAIVLKGVQR 296

Query: 248 AEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVR-----GRIPVFIDSGVR 302
            ED  +A + G + + +SNHG RQLD     I+ L EV  ++R      +I V++D G+R
Sbjct: 297 VEDVVKAAECGIEAVILSNHGGRQLDYSEPPIEVLAEVMPTLRELGLHDKIEVYLDGGIR 356

Query: 303 RGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDI 362
           RG+D++KAL LGA  V IGRP ++ +A  G++GV + + + KDE +  M+L GC  +  +
Sbjct: 357 RGSDILKALCLGARGVGIGRPFLYAMAGYGQKGVEKAIRIYKDELERNMRLLGCTSMDQL 416

Query: 363 RRDLV 367
              LV
Sbjct: 417 HPGLV 421

gb|AAM80552.1| Hmo [Streptomyces toyocaensis]
(366 aa)

Score: 238 bits (607), Expect: 2.09235e-61
Length: 349, Idn/Pos/Gap = 153/209/4 (43%/59%/1%)

Query:  16 LAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVM  75
           LA++   A + LPA V  + A G+  E TL  N  A  R+   PRVL DVSR      ++
Sbjct:  15 LADFERAAASVLPADVRDFVAGGSGAEVTLDANRTALDRVFLVPRVLRDVSRCTADSTLL  74

Query:  76 GIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPK 135
              +  P+ VAP A Q++ HP+GE A ARA    G     S+ ++  +E++ A   G   
Sbjct:  75 KRPVPMPVAVAPVAYQQLVHPDGERAAARAAKAAGVPFTASTLSSVPIEELTA--IGGTV 132

Query: 136 FFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANFA 195
           +FQLY  +D A +  LVRRAE AG  AI LTVD P +GRR  D+RN+F LP H+  AN +
Sbjct: 133 WFQLYRLRDAAQSLELVRRAEDAGCEAIMLTVDVPWMGRRLRDVRNRFALPSHVRAANIS 192

Query: 196 DMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQRAL 255
                   +  A +S +A +      ++  W+ +A L+  TRLP+LLKGV+ AEDA RA+
Sbjct: 193 TGS--TAHRRHADSSAVAVHTGQAFSSATTWSSLAALRKQTRLPLLLKGVLAAEDAVRAV 250

Query: 256 QYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALALGA 315
           + G D + +SNHG RQLDG   +ID L EVA +V     V +DSG+R GTDV++ALALGA
Sbjct: 251 ESGVDAVVVSNHGGRQLDGAVPSIDVLPEVAAAVNDGCEVLLDSGIRSGTDVLRALALGA 310

Query: 316 DAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRR 364
             VL+GRP++WGLA  GE G  R+L LL DE + A+ L GC  V+  R+
Sbjct: 311 SGVLVGRPLIWGLAAAGEAGARRVLDLLADELRDALGLSGCDGVAAARQ 359

ref|ZP_00306006.1| COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Ferroplasma acidarmanus]
(388 aa)

Score: 238 bits (607), Expect: 2.16336e-61
Length: 370, Idn/Pos/Gap = 136/212/11 (36%/57%/2%)

Query:  13 PLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITK  72
           P++L  +   A+  L    +GY    A  E T+ +N +AF R R RPR L DV   + + 
Sbjct:  23 PVSLESWRSSARMALQDGPWGYLEGAAGSEDTMIENIKAFSRYRIRPRYLHDVENRNQSI  82

Query:  73 QVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPG 132
            + G     P ++AP  +Q + H + E A+A A A +G    LS+ ++TS+ED+AA  P 
Sbjct:  83 TLFGRKQDSPFIIAPIGVQSIIHKDAEYASAGAAASLGMPYILSTVSSTSIEDIAAKFPE 142

Query: 133 LPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLS-- 190
             K+FQLY  KD  + + +V RAE+AG++ I +TVDT  LG RE DI+N +   P L   
Sbjct: 143 SEKWFQLYPGKDENVMKSMVNRAEKAGYKVIVVTVDTTMLGWREQDIKNAYL--PFLQGE 200

Query: 191 -LANFADMKDFAQVKGGAGASGLASYVASL----IDASLNWNDIAWLKSITRLPILLKGV 245
            +ANF    +F ++   +  + + + +       ++ S  W+    ++S T+LPIL+KG+
Sbjct: 201 GIANFITDPEFLKMLETSPENNMQAAIEEFLMVYVNPSFTWDGFRKIRSWTKLPILIKGI 260

Query: 246 VTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGT 305
            + ED   A++YGADG+ ISNHG RQ+DG  ++++ L+E+    +    +  DSG+R   
Sbjct: 261 SSEEDVHTAVKYGADGVIISNHGGRQVDGSISSLEALDEITGENKPEFTILFDSGIRHAA 320

Query: 306 DVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRD 365
           D +KALALGA  VLIGRP  + +AV G+ G+ R L+ L+ EF L M L G   +S + R 
Sbjct: 321 DAMKALALGASGVLIGRPYCYAMAVAGQRGIERYLNQLRAEFDLQMALSGYSSISQLGRH 380

Query: 366 LVVRDAFAPY 375
            + +   +PY
Sbjct: 381 TIYKK--SPY 388

gb|AAK33443.1| putative lactate oxidase [Streptococcus pyogenes M1 GAS]
ref|NP_268722.1| putative lactate oxidase [Streptococcus pyogenes M1 GAS]
(395 aa)

Score: 238 bits (606), Expect: 2.89706e-61
Length: 350, Idn/Pos/Gap = 130/193/9 (37%/55%/2%)

Query:  14 LNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQ  73
           +N+ +    A+  +P   +GY ASGA D  TL +N  +F      P  L  V        
Sbjct:  32 INVFDLEKMAQQVIPKGAFGYIASGAGDTFTLHENIRSFNHKLIVPHSLKGVENPSTEIT  91

Query:  74 VMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGL 133
             G  L+ PL++AP A  ++A+ +GE+A+A+ +   G++   SS++TT L +++A + G 
Sbjct:  92 FDGDYLTSPLILAPVAAHKLANEQGEVASAKGLKEFGSIYTTSSYSTTDLPEISAALGGT 151

Query: 134 PKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLAN 193
           P +FQ Y  KD  I   ++ R +  G +AI LT D    G RE D RN F  P  + +  
Sbjct: 152 PHWFQFYYSKDDGINRNIMDRVKAQGCKAIVLTADATVGGNREVDRRNGFVFPVGMPIVQ 211

Query: 194 FADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQR 253
                    +  GAG +    YV      +L   DI ++ + + LP+ +KG   AED  R
Sbjct: 212 -------EYLPDGAGKT--MDYVYKSAKQALTSKDIEYIATYSGLPVYVKGPQCAEDTLR 262

Query: 254 ALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALAL 313
           AL  GA GIW++NHG RQLDG  A  D L+EVA++V  ++P+  DSG+RRG  + KALA 
Sbjct: 263 ALDAGASGIWVTNHGGRQLDGGPAAFDSLQEVAEAVDQKVPIVFDSGIRRGQHIFKALAS 322

Query: 314 GADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIR 363
           GAD V +GRP ++GLA+ G  G  ++   L DE K+ MQL G Q + D++
Sbjct: 323 GADLVALGRPAIYGLAMGGSIGTRQVFEKLNDELKMVMQLAGTQTIQDVK 372

ref|ZP_00361558.1| COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Polaromonas sp. JS666]
(383 aa)

Score: 238 bits (606), Expect: 3.28331e-61
Length: 373, Idn/Pos/Gap = 126/206/20 (33%/55%/5%)

Query:  15 NLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQV  74
           N+ +  + A+ R+P M Y Y  SG+  E T R NE  F++++ R RV +++       ++
Sbjct:   6 NIEDLRVLAQKRVPRMFYDYADSGSWTESTYRANESDFQKIKLRQRVAVNMENRSTATRM  65

Query:  75 MGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLP 134
           +G+D++ P+ +AP  +  M H +GE+  A+A  + G    LS+ +  S+ED+AAH    P
Sbjct:  66 VGLDVTMPVAIAPVGLTGMQHADGEILAAKAAEKFGIPFILSTMSICSIEDIAAHTQS-P 124

Query: 135 KFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANF 194
            +FQLY+ +DR     ++ RA +A   A+ LT+D   +G+R  D++N    PP  +LAN 
Sbjct: 125 FWFQLYMMRDRDAMAAMIERARKARCTALVLTLDLQVIGQRHKDLKNGLTAPPKPTLANI 184

Query: 195 ADMKD-------------------FAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSI 235
            ++                        VKG +    L+++     D  L+W D+AW+K  
Sbjct: 185 INLMTKPRWCLGMAGTKRHTFGNLVGHVKGVSDMRSLSAWTNEQFDPRLSWADVAWVKER 244

Query: 236 TRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPV 295
               ++LKG+   EDA+ A+Q GAD I +SNHG RQLDG  ++I+ L  +  +V   I V
Sbjct: 245 WGGKLILKGIQDVEDAKLAVQSGADAIVVSNHGGRQLDGAQSSIEALPAIVDAVGANIEV 304

Query: 296 FIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCG 355
           ++D G+R G DV+KA ALGA   LIGR +V+GL   GE GV + L ++  E  + M  CG
Sbjct: 305 WMDGGIRSGQDVLKAWALGARGTLIGRAMVYGLGAMGEAGVTKALQIIHKELDITMAFCG 364

Query: 356 CQKVSDIRRDLVV 368
              ++ + + +++
Sbjct: 365 RTDINTVDKGILL 377

gb|AAC15503.1| S-mandelate dehydrogenase [Pseudomonas putida]
sp|P20932|MDLB_PSEPU L(+)-mandelate dehydrogenase (S-mandelate dehydrogenase) (MDH)
(393 aa)

Score: 237 bits (605), Expect: 3.59892e-61
Length: 384, Idn/Pos/Gap = 146/216/26 (38%/56%/6%)

Query:  14 LNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQ  73
            N+ +Y    + RLP MVY Y   GA+DE  ++ N + F++ RF+P+ L+DVSR  +  +
Sbjct:   6 FNVEDYRKLRQKRLPKMVYDYLEGGAEDEYGVKHNRDVFQQWRFKPKRLVDVSRRSLQAE  65

Query:  74 VMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGL 133
           V+G   S PL++ PT +     P+G+LA ARA  + G    LS+ +  S+ED+A    G 
Sbjct:  66 VLGKRQSMPLLIGPTGLNGALWPKGDLALARAATKAGIPFVLSTASNMSIEDLARQCDG- 124

Query: 134 PKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLAN 193
             +FQLYV   R I + +V +A   G+  + LT D    G RE D+ N+F++P   S   
Sbjct: 125 DLWFQLYVIH-REIAQGMVLKALHTGYTTLVLTTDVAVNGYRERDLHNRFKIPMSYSAKV 183

Query: 194 FAD-------MKDFAQVKGGAGASGLASYVASL----------IDASLNWNDIAWLKSIT 236
             D         DF +      A+ ++S  +SL          +DAS NW  + WL+ + 
Sbjct: 184 VLDGCLHPRWSLDFVRHGMPQLANFVSSQTSSLEMQAALMSRQMDASFNWEALRWLRDLW 243

Query: 237 RLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSV-RGRIPV 295
              +L+KG+++AEDA R +  GADG+ +SNHG RQLD     I  +E +AQSV +   PV
Sbjct: 244 PHKLLVKGLLSAEDADRCIAEGADGVILSNHGGRQLD---CAISPMEVLAQSVAKTGKPV 300

Query: 296 FIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCG 355
            IDSG RRG+D+VKALALGA+AVL+GR  ++GLA  GE GV  +L+LLK +    +   G
Sbjct: 301 LIDSGFRRGSDIVKALALGAEAVLLGRATLYGLAARGETGVDEVLTLLKADIDRTLAQIG 360

Query: 356 CQKVSDIRRDLVVRDAF---APYD 376
           C  ++ +  D +  +     AP D
Sbjct: 361 CPDITSLSPDYLQNEGVTNTAPVD 384

ref|ZP_00285165.1| COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Enterococcus faecium]
(305 aa)

Score: 237 bits (604), Expect: 5.19532e-61
Length: 308, Idn/Pos/Gap = 130/190/4 (42%/61%/1%)

Query:  27 LPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGIDLSFPLMVA  86
           + A  +GY   G++DE T+++N  +F   +  PR+L  +   D+   V GI+L  P++ A
Sbjct:   1 MEAGAFGYIRGGSEDEWTMKENTTSFNTKKIMPRILRGIDSADLHTSVFGIELDTPIIQA  60

Query:  87 PTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFFQLYVYKDRA 146
           P+A Q +AH +GE  TA+ VA  G++  +S++A T+++D A   PG P+FFQLY+ KD  
Sbjct:  61 PSAAQGLAHEKGEADTAKGVAAAGSIFSISTYANTTIKDAADAAPGAPQFFQLYMSKDDR 120

Query: 147 ITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANFADMKDFAQVKGG 206
             E ++ +A  AG +AI LT D+   G RE D+ NQFQ P  L + N A   + +    G
Sbjct: 121 FNEFILNKAVEAGAKAIILTADSTLGGYREEDVINQFQFP--LPMPNLAAYSEQSASGNG 178

Query: 207 AGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQRALQYGADGIWISN 266
            G      Y A+     L  +DI  +K IT LP+++KG+ + EDA  A+  GADGIW+SN
Sbjct: 179 EGKGIAEIYAAA--KQGLTPDDIKTIKEITHLPVIVKGIQSPEDAVIAISAGADGIWVSN 236

Query: 267 HGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVW 326
           HG RQLDG  A+ + L ++A+ V  R+PV  DSGVRRG  V KALA GAD V IGRP+++
Sbjct: 237 HGGRQLDGGPASFEVLPKIAEVVNKRVPVIFDSGVRRGEHVFKALASGADLVAIGRPVIY 296

Query: 327 GLAVDGEE 334
           GL + G++
Sbjct: 297 GLNLVGQK 304

emb|CAD86037.1| glycolate oxidase, (S)-2-hydroxy-acid oxidase, peroxisomal [Nitrosomonas europaea ATCC 19718]
ref|NP_842132.1| glycolate oxidase, (S)-2-hydroxy-acid oxidase, peroxisomal [Nitrosomonas europaea ATCC 19718]
(361 aa)

Score: 236 bits (602), Expect: 9.39488e-61
Length: 354, Idn/Pos/Gap = 139/201/13 (39%/56%/3%)

Query:  17 AEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMG  76
           A+Y   A+ RL   V+ Y   G+ ++ TL  N   F  +R  PR + DV        + G
Sbjct:  19 ADYLPLARERLLPAVWHYLEEGSGNQVTLHTNNCVFDSIRLIPRPMADVRDGHTRITLFG  78

Query:  77 IDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKF 136
             L+ P+++AP A QR+ HP GE A+A A    G  + +SS A+ +LE++     G P +
Sbjct:  79 QTLAHPVILAPLAYQRLYHPHGESASAMAANAQGGQLCVSSLASQTLEEIIT-AAGQPLW 137

Query: 137 FQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANFAD 196
           FQLY  +DR  T +L+RRA  AG++AI  TVD P    ++A I    QLP  +S  N   
Sbjct: 138 FQLYWQEDRPRTLKLLRRAVTAGYQAIVFTVDAPI---KQATI----QLPASISAVNLDT 190

Query: 197 MKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQRALQ 256
              F      A     +      +  +  W D+AWL++ T LP+L+KG++  EDA++ + 
Sbjct: 191 PAPFP-----ALLPHQSQVFNGWMAQAPRWEDLAWLRAQTSLPLLVKGILHPEDARKVIN 245

Query: 257 YGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALALGAD 316
            G DG+ +SNHG R LDG  A++ CL E+  +V GR  V  DSG+R G D+ KALALGAD
Sbjct: 246 LGYDGLVVSNHGGRVLDGAPASLACLPEIVSTVSGRGKVLFDSGIRNGRDIYKALALGAD 305

Query: 317 AVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLVVRD 370
           AVLIGRP +WGLA  G  GV  ++ LL+DE ++ M L G   + +I R+ ++ D
Sbjct: 306 AVLIGRPYIWGLATVGALGVAHVIRLLRDELEMTMALTGTASIREITREKIISD 359

gb|AAT09795.1| NocN [Nocardia uniformis subsp. tsuyamanensis]
(376 aa)

Score: 236 bits (601), Expect: 1.21681e-60
Length: 362, Idn/Pos/Gap = 150/204/3 (41%/56%/0%)

Query:   2 VEKPAVNPATQPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRV  61
           V   A   A  P +LAE    A ARLP  V  + A G+ DE TL  N  A   +   PRV
Sbjct:   3 VRNSAGGGAEDPEDLAEVERAAAARLPGDVRDFIAGGSGDEVTLAANRAALDDVALLPRV  62

Query:  62 LIDVSRVDITKQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATT 121
           L  V   D +  ++G   + P+ VAP   Q + HP+GE+A A A    G    + + ++ 
Sbjct:  63 LAGVQAADTSTSLVGTAATLPVAVAPMGYQCLVHPDGEVAAAAAAGAAGVPFTVGTLSSR 122

Query: 122 SLEDVAAHVPGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRN 181
           S+E++A    G   +FQLY  +DR +   LV RAE AG RA+ +TVD P +GRR  D+RN
Sbjct: 123 SVEEIAE--TGASLWFQLYWLRDRGLVAELVARAEAAGCRALVITVDVPVMGRRLRDVRN 180

Query: 182 QFQLPPHLSLANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPIL 241
              LP  +   + AD    A      G SG+A + +++ D +  W D+ WL++ TRLP++
Sbjct: 181 GITLPRTVRAVHLADGPSSAHEPRQVG-SGVAQHTSAVFDPAFGWRDLEWLRARTRLPLV 239

Query: 242 LKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGV 301
           +KGV+   DA R ++ GA  + +SNHG RQLDG   +   L  V  +V G   V  DSGV
Sbjct: 240 VKGVLDPRDATRCVELGASAVVVSNHGGRQLDGAAPSAVALPRVVDAVAGAAEVLFDSGV 299

Query: 302 RRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSD 361
           R G DV++ALALGA  VL+GRPI+WGLAV GE G  R+L LL+ EF  A+ L GC  V  
Sbjct: 300 RGGVDVLRALALGATGVLLGRPILWGLAVGGERGAARVLELLRTEFAQALLLAGCADVDA 359

Query: 362 IR 363
            R
Sbjct: 360 AR 361

ref|YP_112124.1| putative L-lactate dehydrogenase [Burkholderia pseudomallei K96243]
emb|CAH39606.1| putative L-lactate dehydrogenase [Burkholderia pseudomallei K96243]
ref|YP_105174.1| L-lactate dehydrogenase [Burkholderia mallei ATCC 23344]
gb|AAU45915.1| L-lactate dehydrogenase [Burkholderia mallei ATCC 23344]
(380 aa)

Score: 236 bits (601), Expect: 1.25811e-60
Length: 373, Idn/Pos/Gap = 139/207/20 (37%/55%/5%)

Query:  16 LAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVM  75
           + +  + AK R+P M Y Y  +G+  E T R NE  FR++R R RV +D+S  ++   + 
Sbjct:   8 IEDLRVLAKKRIPRMFYDYVDTGSYTESTYRANEADFRKIRLRQRVGVDISNRNLRTTMA  67

Query:  76 GIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPK 135
           G D++ P+ +APT +  M   +GE+  ARA    G    LS+ +  S+ED+ AHV G P 
Sbjct:  68 GQDVAMPVALAPTGLVGMMRADGEILAARAARHFGVPFTLSTMSICSIEDIVAHVGG-PF 126

Query: 136 FFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANFA 195
           +FQLY+ +DRA  ERL+ RA  AG  A+ LT+D    G+R  D++N    PP ++L N  
Sbjct: 127 WFQLYMMRDRAFIERLIERASAAGCPALVLTMDLQIAGQRHKDVKNGLSAPPRITLPNLL 186

Query: 196 DM---------------KDFA----QVKGGAGASGLASYVASLIDASLNWNDIAWLKSIT 236
           DM               + F      VKG      L S+     D ++ W D  W++   
Sbjct: 187 DMMRKPGWCLGMARTRRRHFGNIVGHVKGVTDMWSLDSWTREQFDPTIGWRDAEWVRRRW 246

Query: 237 RLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVF 296
              +++KGV+ A+DA RA   GAD I +SNHG RQLDG  ++I+ L  + ++   R+ V+
Sbjct: 247 NGKLIVKGVLDADDALRAADAGADAIVVSNHGGRQLDGAMSSIEALPAIVEAAGKRVEVW 306

Query: 297 IDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGC 356
           +D GVR G DV+KA+ALGA   +IGR  ++G+A  GE+G  R L L+  E    M LCGC
Sbjct: 307 LDGGVRTGQDVLKAVALGARGTMIGRAFLYGVAALGEQGARRALELIARELDTTMALCGC 366

Query: 357 QKVSDIRRDLVVR 369
             +  +  D++ R
Sbjct: 367 TDIRSVNADVLAR 379

ref|NP_245225.1| LldD [Pasteurella multocida subsp. multocida str. Pm70]
gb|AAK02372.1| LldD [Pasteurella multocida subsp. multocida str. Pm70]
(388 aa)

Score: 235 bits (600), Expect: 1.33378e-60
Length: 376, Idn/Pos/Gap = 128/204/20 (34%/54%/5%)

Query:  16 LAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVM  75
           L +    A+ ++P M Y Y  SG+  E TL  N   F+ ++ R RVL+D+    +   ++
Sbjct:  10 LEDLRRVAQRKVPKMFYDYVVSGSWSESTLHANRNDFQAIKLRQRVLVDMEGRSLESTMI  69

Query:  76 GIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPK 135
           G  +  PL +APT    M HP+GE+  ARA  + G    LS+ +  S+EDVA H    P 
Sbjct:  70 GQQVKMPLAIAPTGFTGMVHPDGEIHAARAAEKFGIPFSLSTMSICSIEDVAEHTSA-PF 128

Query: 136 FFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANFA 195
           +FQLYV +DR     L++RA+ A   A+ LT D   LG+R  DI+N    PP  +L N+ 
Sbjct: 129 WFQLYVMRDREFMRNLIKRAQAAKCSALILTADLQVLGQRHRDIKNGLSAPPKPTLRNWI 188

Query: 196 DM---------------KDFAQVKGGAGASG----LASYVASLIDASLNWNDIAWLKSIT 236
           ++               + F  + G A   G    L S+ +   D  L+W+D+A +K++ 
Sbjct: 189 NLATKLEWSLKMLGTQRRTFRNIVGHAKNVGDLSSLTSWTSEQFDPRLSWDDVAEIKALW 248

Query: 237 RLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVF 296
              +++KG++  EDA+ A++ GAD I +SNHG RQLDG  ++I  L  +  +V   I V+
Sbjct: 249 GGKLIIKGIMEPEDAEMAVKSGADAIVVSNHGGRQLDGALSSIQALPNIVSAVGNEIEVW 308

Query: 297 IDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGC 356
           +DSG+  G D++KA A+GA   + G+  + GL   GE GV+RLL +   E  ++M   G 
Sbjct: 309 LDSGITSGQDMLKAWAMGARGFMTGKAFLHGLGAYGEAGVHRLLEIFYKEMDVSMAFTGH 368

Query: 357 QKVSDIRRDLVVRDAF 372
           + + D+   ++V+  +
Sbjct: 369 RNLKDVTEAILVKGTY 384

ref|NP_664101.1| putative lactate oxidase [Streptococcus pyogenes MGAS315]
gb|AAM78904.1| putative lactate oxidase [Streptococcus pyogenes MGAS315]
(393 aa)

Score: 235 bits (600), Expect: 1.49905e-60
Length: 350, Idn/Pos/Gap = 129/192/9 (36%/54%/2%)

Query:  14 LNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQ  73
           +N+ +    A+  +P   +GY ASGA D  TL +N  +F      P  L  V        
Sbjct:  30 INVFDLEKMAQQVIPKGAFGYIASGAGDTFTLHENIRSFNHKLIVPHSLKGVENPSTEIT  89

Query:  74 VMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGL 133
             G  L+ PL++AP A  ++A+ +GE+A+A+ +   G++   SS++TT L +++A + G 
Sbjct:  90 FDGDYLTSPLILAPVAAHKLANEQGEVASAKGLKEFGSIYTTSSYSTTDLPEISAALGGT 149

Query: 134 PKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLAN 193
           P +FQ Y  KD  I   ++ R +  G +AI LT D    G RE D RN F  P  + +  
Sbjct: 150 PHWFQFYYSKDDGINRNIMDRVKAQGCKAIVLTADATVGGNREVDRRNGFVFPVGMPIVQ 209

Query: 194 FADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQR 253
                    +  GAG +    YV      +L   DI ++ + + LP+ +KG   AED  R
Sbjct: 210 -------EYLPDGAGKT--MDYVYKSAKQALTSKDIEYIATYSGLPVYVKGPQCAEDTLR 260

Query: 254 ALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALAL 313
           AL  GA GIW++NHG RQLDG  A  D L+EVA++V  ++P+  DSG+R G  + KALA 
Sbjct: 261 ALDAGASGIWVTNHGGRQLDGGPAAFDSLQEVAEAVDHKVPIVFDSGIRWGQHIFKALAS 320

Query: 314 GADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIR 363
           GAD V +GRP ++GLA+ G  G  ++   L DE K+ MQL G Q + D++
Sbjct: 321 GADLVALGRPAIYGLAMGGSIGTRQVFEKLNDELKMVMQLAGTQTIQDVK 370

ref|NP_802822.1| putative lactate oxidase [Streptococcus pyogenes SSI-1]
dbj|BAC64655.1| putative lactate oxidase [Streptococcus pyogenes SSI-1]
(395 aa)

Score: 235 bits (599), Expect: 1.81618e-60
Length: 350, Idn/Pos/Gap = 129/192/9 (36%/54%/2%)

Query:  14 LNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQ  73
           +N+ +    A+  +P   +GY ASGA D  TL +N  +F      P  L  V        
Sbjct:  32 INVFDLEKMAQQVIPKGAFGYIASGAGDTFTLHENIRSFNHKLIVPHSLKGVENPSTEIT  91

Query:  74 VMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGL 133
             G  L+ PL++AP A  ++A+ +GE+A+A+ +   G++   SS++TT L +++A + G 
Sbjct:  92 FDGDYLTSPLILAPVAAHKLANEQGEVASAKGLKEFGSIYTTSSYSTTDLPEISAALGGT 151

Query: 134 PKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLAN 193
           P +FQ Y  KD  I   ++ R +  G +AI LT D    G RE D RN F  P  + +  
Sbjct: 152 PHWFQFYYSKDDGINRNIMDRVKAQGCKAIVLTADATVGGNREVDRRNGFVFPVGMPIVQ 211

Query: 194 FADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQR 253
                    +  GAG +    YV      +L   DI ++ + + LP+ +KG   AED  R
Sbjct: 212 -------EYLPDGAGKT--MDYVYKSAKQALTSKDIEYIATYSGLPVYVKGPQCAEDTLR 262

Query: 254 ALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALAL 313
           AL  GA GIW++NHG RQLDG  A  D L+EVA++V  ++P+  DSG+R G  + KALA 
Sbjct: 263 ALDAGASGIWVTNHGGRQLDGGPAAFDSLQEVAEAVDHKVPIVFDSGIRWGQHIFKALAS 322

Query: 314 GADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIR 363
           GAD V +GRP ++GLA+ G  G  ++   L DE K+ MQL G Q + D++
Sbjct: 323 GADLVALGRPAIYGLAMGGSIGTRQVFEKLNDELKMVMQLAGTQTIQDVK 372

ref|NP_928426.1| hypothetical protein plu1106 [Photorhabdus luminescens subsp. laumondii TTO1]
emb|CAE13400.1| unnamed protein product [Photorhabdus luminescens subsp. laumondii TTO1]
(382 aa)

Score: 234 bits (597), Expect: 3.59996e-60
Length: 372, Idn/Pos/Gap = 138/208/23 (37%/55%/6%)

Query:  14 LNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQ  73
           LN+A+Y   AK +LP +++ Y   GA+DE+ LR N++ F R RF P  LIDVS+ DI+  
Sbjct:   6 LNVADYRTLAKKKLPKIIFDYLEGGAEDEKGLRYNQQIFDRWRFIPHRLIDVSKRDISCT  65

Query:  74 VMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGL 133
           +     S P  +APT +     P G+L  AR  A+      LSS A  ++EDVA    G 
Sbjct:  66 LFNKVWSAPFAIAPTGLNATFRPNGDLILARVAAKENIPFILSSAANMTIEDVARQCDG- 124

Query: 134 PKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLAN 193
            K+FQLYV     + E++V+RA  + +  + +TVD    G RE DIRNQF LP     A 
Sbjct: 125 EKWFQLYVVCPE-LAEQMVKRALASDYTTLVITVDVAVNGYRERDIRNQFCLPLRYRPAV 183

Query: 194 FAD------------------MKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSI 235
             D                  + +F   +   G     + ++  +DAS NW  +  L+++
Sbjct: 184 LLDGCLHPSWLLRFLCNGMPQLANFVMTE-NIGVDVQVAVMSRQMDASFNWQSLEQLRAL 242

Query: 236 TRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPV 295
               +L+KG+V  E+A++ ++ GADG+ +SNHG RQLDG  + ++ L    Q++    PV
Sbjct: 243 WPHKLLVKGLVRPEEAKKCIELGADGVILSNHGGRQLDGTLSPMETLSATVQAMYQ--PV 300

Query: 296 FIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCG 355
            IDSG RRG+D+VKALALGA+ VL+GR +++GLA  GE+GV  ++ LLK++ +  +   G
Sbjct: 301 LIDSGFRRGSDIVKALALGANMVLLGRAVLYGLAATGEQGVSEVIRLLKEDIERTLVHIG 360

Query: 356 CQKVSDIRRDLV 367
              +  +  D V
Sbjct: 361 SPSIRGLTPDFV 372

ref|ZP_00338510.1| COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Silicibacter sp. TM1040]
(387 aa)

Score: 234 bits (596), Expect: 4.32532e-60
Length: 367, Idn/Pos/Gap = 135/205/21 (36%/55%/5%)

Query:  26 RLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGIDLSFPLMV  85
           R+P M Y Y  SG+  EQT R+N   F ++R R RV +D++      Q++G D++ P+ +
Sbjct:  17 RVPKMFYDYAESGSWTEQTFRENSTDFDQIRLRQRVAVDMAGRSTASQMIGQDVAMPVAL  76

Query:  86 APTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFFQLYVYKDR 145
           AP  +  M   +GE+  ARA    G    LS+ +  S+E+V+      P +FQLY  KD 
Sbjct:  77 APVGLTGMQCADGEIKAARAAEAFGVPFTLSTMSINSIEEVS-EATSKPFWFQLYTMKDD 135

Query: 146 AITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANFADM-------- 197
               RL+ RA+ A   A+ +T+D   LG+R  D++N    PP L+    A++        
Sbjct: 136 DYIRRLIARAKDANCSALVITLDLQILGQRHKDLKNGLSAPPKLTPKTIANLMTKWAWGI 195

Query: 198 -------KDFA----QVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVV 246
                  ++F      V+G + AS L S+ A   D SL+W  I  LK +    ++LKG++
Sbjct: 196 EMLGAKRRNFGNIVGHVEGVSDASSLGSWTAEQFDPSLDWGKIEKLKEMWGGKVILKGIL 255

Query: 247 TAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTD 306
             EDA+ A + GAD I +SNHG RQLDG  ++I  L  +  +V  ++ V +DSG+R G D
Sbjct: 256 DEEDAKMAAKVGADAITVSNHGGRQLDGALSSIRMLPRIMDAVGDQVEVHLDSGIRSGQD 315

Query: 307 VVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDI-RRD 365
           V+KALALGA   +IGR  V+GL   G++GV R L ++  E   +M LCG + V+D+ R +
Sbjct: 316 VLKALALGATGTMIGRAFVYGLGAMGQKGVTRALEVIHKELDTSMALCGEKHVTDLGRHN 375

Query: 366 LVVRDAF 372
           L+V + F
Sbjct: 376 LLVPEDF 382

ref|ZP_00379459.1| COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Brevibacterium linens BL2]
(405 aa)

Score: 233 bits (594), Expect: 8.01988e-60
Length: 353, Idn/Pos/Gap = 135/196/13 (38%/55%/3%)

Query:  23 AKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGIDLSFP  82
           AK   P   + Y   GA DE TLR N + F  +   PR+L  V   + +  + G D+S P
Sbjct:  35 AKRVTPTAPFDYVDGGALDEHTLRKNRQVFADVELLPRILHGVDAPNTSTTIAGQDVSLP  94

Query:  83 LMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFFQLYVY 142
             +APT   RM H EGE+   RA  + G    LS+  T S+E+VA   P   ++FQLY++
Sbjct:  95 FGIAPTGYTRMMHSEGEIGGVRAATKAGIPFSLSTMGTRSIEEVAQAAPSSTRWFQLYLW 154

Query: 143 KDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANFADMK---- 198
           KDRA +  L++RA+ +G+  + +TVDTP  G+R  D RN   +PP L+L    D      
Sbjct: 155 KDRARSLDLLQRAQASGYETLLVTVDTPITGQRLRDNRNGLSIPPKLTLKTIVDASYRPG 214

Query: 199 ---DFAQVKGGAGAS------GLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAE 249
              +F   +    AS       LA    ++ D +L+ +D+ W++   +  + +KGV+TAE
Sbjct: 215 WWFNFLTTEPPKYASLSNTSQSLAEMTRTMFDPTLDLDDLKWIREQWQGKLFVKGVLTAE 274

Query: 250 DAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVK 309
           DA RA   GADG+ +SNHG RQLD    ++  L EV  +V   + + +DSG+  GTDVV 
Sbjct: 275 DANRARSIGADGLVVSNHGGRQLDRAPDSLTALAEVRAAVGDDMELILDSGIMSGTDVVT 334

Query: 310 ALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDI 362
           AL  GAD VLIGR  ++GL   G+ GV R + L+K E   AM L G + ++D+
Sbjct: 335 ALCAGADFVLIGRAYLYGLMAGGQRGVERAIDLIKAEILTAMGLMGARTIADL 387

sp|P21795|LA2M_MYCSM Lactate 2-monooxygenase (Lactate oxidase)
pir||A35745 lactate 2-monooxygenase (EC 1.13.12.4) - Mycobacterium smegmatis
gb|AAA60429.1| L-lactate 2-monooxygenase
(394 aa)

Score: 232 bits (591), Expect: 1.65739e-59
Length: 368, Idn/Pos/Gap = 137/202/14 (37%/54%/3%)

Query:  11 TQPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDI  70
           T P++ A++   A+  LP  V  Y A G+ DE T R N EAF+     PR+L+  +  D+
Sbjct:  22 TLPMSYADWEAHAQQALPPGVLSYVAGGSGDEHTQRANVEAFKHWGLMPRMLMAATERDL  81

Query:  71 TKQVMGIDLSFPLMVAPTAMQRMAHPEG--ELATARAVARIGTVMGLSSWATTSLEDVAA 128
           + ++ G   + P+  AP  +  +   +G  + A+A+A AR G     S+ A +SLED+  
Sbjct:  82 SVELWGKTWAAPMFFAPIGVIALCAQDGHGDAASAQASARTGVPYITSTLAVSSLEDIRK 141

Query: 129 HVPGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIR-NQFQLPP 187
           H    P +FQLY  +DR + E  +RRAE AG+  + +T+DT   G R  D+  + F    
Sbjct: 142 HAGDTPAYFQLYYPEDRDLAESFIRRAEEAGYDGLVITLDTWIFGWRPRDLTISNFPFLR 201

Query: 188 HLSLANFADMKDFAQ---VKGGAGASGL-------ASYVASLIDASLNWNDIAWLKSITR 237
            L L N+     F +      G  A GL       A +   L   S+ W DI W++SIT+
Sbjct: 202 GLCLTNYVTDPVFQKKFKAHSGVEAEGLRDNPRLAADFWHGLFGHSVTWEDIDWVRSITK 261

Query: 238 LPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFI 297
           +P++LKG+   +DA+RA+  G DGI+ SNHG RQ +G    +DCL EV ++  G  PV  
Sbjct: 262 MPVILKGIQHPDDARRAVDSGVDGIYCSNHGGRQANGGLPALDCLPEVVKA-SGDTPVLF 320

Query: 298 DSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQ 357
           DSG+R G DVVKALA+GA AV IGRP  WG A+ G +G+  +   L  E  L M + G +
Sbjct: 321 DSGIRTGADVVKALAMGASAVGIGRPYAWGAALGGSKGIEHVARSLLAEADLIMAVDGYR 380

Query: 358 KVSDIRRD 365
            + ++  D
Sbjct: 381 NLKELTID 388

emb|CAA04759.1| L-mandelate dehydrogenase [Rhodotorula graminis]
(491 aa)

Score: 231 bits (590), Expect: 2.11111e-59
Length: 361, Idn/Pos/Gap = 139/209/12 (38%/57%/3%)

Query:  16 LAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVM  75
           L E+   ++  L  M   YY +GA+ EQTLRD  EA++R+RFRPRVL  +  +D     +
Sbjct: 123 LDEFEEISQKILSEMAMAYYGTGAETEQTLRDEREAWQRVRFRPRVLRKMRHIDTNTTFL 182

Query:  76 GIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDV-AAHVPGLP 134
           GI    P+ VAP  + R+ HP+GE    R VA+   +  +SS A+ S++++     P   
Sbjct: 183 GIPTPLPIFVAPAGLARLGHPDGEQNIVRGVAKHDILQVVSSGASCSIDEIFEVKEPDQN 242

Query: 135 KFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADI----RNQFQLPPHLS 190
             +Q YV+ D+ I E  ++RA   G +AI +TVD P LG+RE D+    R+Q    P  +
Sbjct: 243 LAWQFYVHSDKKIAEEKLKRALALGAKAIFVTVDVPVLGKRERDLKLKARSQNYEHPIAA 302

Query: 191 LANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKS-ITRLPILLKGVVTAE 249
               A  K   +     G S +     + IDA+LNW+DIAW+K     +PI++KGV   E
Sbjct: 303 QWKAAGSK-VEETIAKRGVSDIPD--TAHIDANLNWDDIAWIKERAPGVPIVIKGVGCVE 359

Query: 250 DAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQ---SVRGRIPVFIDSGVRRGTD 306
           D + A QYGADG+ +S HGARQLDG  A +D L EV +   ++   I V++D   RRGTD
Sbjct: 360 DVELAKQYGADGVVLSTHGARQLDGARAPLDVLIEVRRKNPALLKEIEVYVDGQARRGTD 419

Query: 307 VVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDL 366
           V+KAL LGA  V  GR  ++  +  G +GV + + +L++E + AM+L G   ++D++ ++
Sbjct: 420 VLKALCLGARGVGFGRGFLYAQSAYGADGVDKAIRILENEIQNAMRLLGANTLADLKPEM 479

Query: 367 V 367
           V
Sbjct: 480 V 480

emb|CAA04758.1| L-mandelate dehydrogenase [Rhodotorula graminis]
(565 aa)

Score: 230 bits (586), Expect: 5.69802e-59
Length: 361, Idn/Pos/Gap = 139/209/12 (38%/57%/3%)

Query:  16 LAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVM  75
           L E+   ++  L  M   YY +GA+ EQTLRD  EA++R+RFRPRVL  +  +D     +
Sbjct: 197 LDEFEEISQKILSEMAMAYYGTGAETEQTLRDEREAWQRVRFRPRVLRKMRHIDTNTTFL 256

Query:  76 GIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDV-AAHVPGLP 134
           GI    P+ VAP  + R+ HP+GE    R VA+   +  +SS A+ S++++     P   
Sbjct: 257 GIPTPLPIFVAPAGLARLGHPDGEQNIVRGVAKHDILQVVSSGASCSIDEIFEVKEPDQN 316

Query: 135 KFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADI----RNQFQLPPHLS 190
             +Q YV+ D+ I E  ++RA   G +AI +TVD P LG+RE D+    R+Q    P  +
Sbjct: 317 LAWQFYVHSDKKIAEEKLKRALALGAKAIFVTVDVPVLGKRERDLKLKARSQNYEHPIAA 376

Query: 191 LANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKS-ITRLPILLKGVVTAE 249
               A  K   +     G S +     + IDA+LNW+DIAW+K     +PI++KGV   E
Sbjct: 377 QWKAAGSK-VEETIAKRGVSDIPD--TAHIDANLNWDDIAWIKERAPGVPIVIKGVGCVE 433

Query: 250 DAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQ---SVRGRIPVFIDSGVRRGTD 306
           D + A QYGADG+ +S HGARQLDG  A +D L EV +   ++   I V++D   RRGTD
Sbjct: 434 DVELAKQYGADGVVLSTHGARQLDGARAPLDVLIEVRRKNPALLKEIEVYVDGQARRGTD 493

Query: 307 VVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDL 366
           V+KAL LGA  V  GR  ++  +  G +GV + + +L++E + AM+L G   ++D++ ++
Sbjct: 494 VLKALCLGARGVGFGRGFLYAQSAYGADGVDKAIRILENEIQNAMRLLGANTLADLKPEM 553

Query: 367 V 367
           V
Sbjct: 554 V 554

ref|ZP_00006991.2| COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Rhodobacter sphaeroides 2.4.1]
gb|AAD29267.1| lactate dehydrogenase [Rhodobacter sphaeroides]
(387 aa)

Score: 228 bits (581), Expect: 2.49522e-58
Length: 369, Idn/Pos/Gap = 133/201/21 (36%/54%/5%)

Query:  24 KARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGIDLSFPL  83
           + R P M + Y  SG+  EQT RDN   F+++R R +V +D+       +++G  ++ P+
Sbjct:  15 RRRAPRMFFDYCESGSYTEQTFRDNCSDFQKIRLRQKVAVDMLGRSTRSEMIGEPVAMPV  74

Query:  84 MVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFFQLYVYK 143
            +AP  M  M   +GE+  ARA    G    LS+ +  S+EDVAA     P +FQLYV K
Sbjct:  75 ALAPVGMTGMQCADGEIKAARAAEAFGVPYTLSTMSICSVEDVAAATTK-PFWFQLYVMK 133

Query: 144 DRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANFADM------ 197
           D    + ++ R ++AG  A+ LT+D   LG+R  D+RN    PP ++L    D+      
Sbjct: 134 DEEFVDGMLERVKKAGCSALVLTLDLQILGQRHKDLRNGLSAPPKMTLPVMLDLATKWGW 193

Query: 198 ---------KDFAQV----KGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKG 244
                    + F  +    KG    S LAS+ A   D  L+W  IA L+      ++LKG
Sbjct: 194 GLEMLKTHRRSFGNIVGHAKGVGDTSSLASWTAEQFDPQLDWGKIARLRDKWGGKLILKG 253

Query: 245 VVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRG 304
           ++  EDA+RA  +GAD I +SNHG RQLDG  ++I  L  + ++V  ++ + +D G+R G
Sbjct: 254 ILDEEDARRAADFGADAIIVSNHGGRQLDGALSSIRMLPPIVRAVGDQVEIHMDGGIRSG 313

Query: 305 TDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDI-R 363
            DV+KALA+GA    IGR  ++GL   GE GV R L ++  E  ++M LCG + V  +  
Sbjct: 314 QDVLKALAMGAKGTFIGRSYIYGLGAMGEAGVRRALEVIWKELDISMALCGEKDVKALGP 373

Query: 364 RDLVVRDAF 372
            +L+V D F
Sbjct: 374 HNLLVPDDF 382

ref|ZP_00199662.1| COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Rubrobacter xylanophilus DSM 9941]
(431 aa)

Score: 228 bits (580), Expect: 3.20493e-58
Length: 406, Idn/Pos/Gap = 150/218/38 (36%/53%/9%)

Query:  11 TQPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDI  70
           T P++       A+ ++    + Y   GA  E T+R+N  AF R R  PRVL  V   D 
Sbjct:  25 TVPVDPGRLERAARRKMGRRAFAYVVGGAGSESTIRENRAAFERWRIVPRVLRGVVGRDA  84

Query:  71 TKQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHV 130
           + ++ G  LS+PL++AP  +  +AH E ++A ARA AR+G     SS A+ ++E+ AA +
Sbjct:  85 SVELFGRRLSYPLLLAPVGVLEVAHREADVAVARAAARLGVPFIFSSQASKTMEECAAAM 144

Query: 131 PGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADI----------- 179
              P++FQLY  +   + E  V RAE  G   I +T+DT  LG R  D+           
Sbjct: 145 GSAPRWFQLYWSESDELVESFVARAESCGCEVIVVTLDTIMLGWRPRDLDLGSLPFLRGM 204

Query: 180 -----------RNQFQLP-------PHLSLANFADMKDFAQ---------VKGGAGASGL 212
                      R     P       P ++ +    +   A+         ++ G   + +
Sbjct: 205 GIAQYTSDPVFRRSLAGPAGGASERPPVTPSTLRALLGLARRHPGGLLRNLRSGEPLAAV 264

Query: 213 ASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQL 272
             +V++    SL W D+A+L+  TRLP+LLKG++  EDA+ AL++GADG+ +SNHG RQ+
Sbjct: 265 RRFVSTYSRTSLRWEDLAFLRERTRLPVLLKGILHPEDARIALEHGADGVIVSNHGGRQV 324

Query: 273 DGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDG 332
           DG  A +D L  V + V GR PV  DSG+R G DV KALALGA AV +GRP V+GLA+ G
Sbjct: 325 DGEIAALDALPGVVEEVGGRAPVLFDSGIRGGADVFKALALGATAVCLGRPYVYGLALAG 384

Query: 333 EEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLVVRDAFAPYDVR 378
           E GV  ++  +  EF L M L GC+ V++I RDL+   A  P   R
Sbjct: 385 ERGVAEVVENVLAEFDLTMGLAGCRSVAEISRDLLAPAATPPRGSR 430

ref|XP_326490.1| hypothetical protein [Neurospora crassa]
gb|EAA32373.1| hypothetical protein [Neurospora crassa]
(698 aa)

Score: 227 bits (579), Expect: 4.29187e-58
Length: 397, Idn/Pos/Gap = 146/213/33 (36%/53%/8%)

Query:   1 MVEKPAVNPATQPLN-LAEYHLF---AKARLPAMVYGYYASGADDEQTLRDNEEAFRRLR  56
           +   P++ P+  PL+ L   H F   A +  P   + +  S A D  T R N   +  + 
Sbjct: 274 LCHDPSLQPSQPPLHTLLSTHDFLSAAASSFPPKTHAFVTSAATDCHTHRSNSHTYSLIT 333

Query:  57 FRPRVLIDVSRVDITKQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLS 116
            RPR+L DVSRV I+ +++   +S P+  A T++    HP+GE A  RA  ++G  M +S
Sbjct: 334 LRPRILHDVSRVSISTRILDHLVSSPIFAAATSLGTTVHPDGEKAIGRACKKLGVGMTIS 393

Query: 117 SWATTSLEDVAAHVPGL---------------------PKFFQLYVYKDRAITERLVRRA 155
           + A+ S+ ++A  V                        P +FQLYV KDR+ +E+L+++A
Sbjct: 394 TSASFSVGEIARAVEDCETVTERKEKEEKEEKEEKAIPPLWFQLYVDKDRSKSEKLLKQA 453

Query: 156 ERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANFADMKDFAQVKGGAGASGLASY 215
             AG +A+ LTVD P  G+READ R   +    LS +      + A+     G  GL   
Sbjct: 454 VDAGVKAVFLTVDAPVPGKREADERISAEEAVGLSSSGVPMTGEKAENDQSGG--GLGRI 511

Query: 216 VASLIDASLNWNDIAWLKSI--TRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLD 273
               +DAS++W DIAWL+      + I+LKGV TA DA RA++ G +GI +SNHG R LD
Sbjct: 512 TGKFLDASVSWGDIAWLRRCLPEEVKIVLKGVQTAADAVRAMEAGVEGIVVSNHGGRSLD 571

Query: 274 GVTATIDCLEEVAQ---SVRGRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAV 330
              ATI  L E+ +    V  ++ V +D GV RGTDV KAL LGA  V IGR I++GL  
Sbjct: 572 TAPATILVLLELQRCCPQVFDKMEVLVDGGVTRGTDVFKALCLGASGVGIGRGILYGLGY 631

Query: 331 DGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLV 367
            GEEGV R + +L DE +  M++CG   +  +   L+
Sbjct: 632 -GEEGVRRYVQILNDELETTMKMCGITSLDQVHPGLL 667

ref|ZP_00244409.1| COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Rubrivivax gelatinosus PM1]
(368 aa)

Score: 227 bits (578), Expect: 5.11379e-58
Length: 362, Idn/Pos/Gap = 128/197/20 (35%/54%/5%)

Query:  30 MVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGIDLSFPLMVAPTA  89
           M Y Y  SG+  E T R NE  F R+  R RV +++    +   + G D + P+++APT 
Sbjct:   1 MFYDYADSGSWTEGTYRANETDFARILLRQRVAVNMEGRSLRTTLAGQDCAMPVVIAPTG  60

Query:  90 MQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFFQLYVYKDRAITE 149
           +  M H +GE+  ARA    G    LS+ +  S+ED+AAH    P +FQLY  +DR   E
Sbjct:  61 LTGMQHADGEILGARAAEAFGVPFTLSTMSICSIEDIAAHTKA-PFWFQLYWMRDRDFME 119

Query: 150 RLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANFADMKD---------- 199
           RL+ RA+ A   A+ LT+D   LG+R  D++N    PP  +LAN  ++            
Sbjct: 120 RLIERAKAARCSALVLTLDLQVLGQRHKDLKNGMTAPPKPTLANLINLAMKPRWCLGMAG 179

Query: 200 ---------FAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAED 250
                        KG +  S L ++     D  L+W+D+AW+K      ++LKG++   D
Sbjct: 180 TRRHSFGNLVGHAKGVSDMSSLGTWTKEQFDPRLSWDDVAWIKQRWGGRLILKGIMEVAD 239

Query: 251 AQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKA 310
           A+ A   GAD I +SNHG RQLDG  ++I  L  +A++V  RI V++D G+R G DV+KA
Sbjct: 240 AKLAADSGADAIVVSNHGGRQLDGAPSSIAALPAIAEAVGDRIEVWMDGGIRSGQDVLKA 299

Query: 311 LALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLVVRD 370
           +ALGA   +IGR  ++GL   G+ GV R L ++++E  + M   G   +  + R+++V  
Sbjct: 300 VALGARGTMIGRAFLYGLGAMGQAGVTRALEIIRNELDITMAFTGHTDIRRVGREILVPG 359

Query: 371 AF 372
           ++
Sbjct: 360 SY 361

ref|NP_801009.1| L-lactate dehydrogenase [Vibrio parahaemolyticus RIMD 2210633]
dbj|BAC62842.1| L-lactate dehydrogenase [Vibrio parahaemolyticus RIMD 2210633]
(379 aa)

Score: 226 bits (577), Expect: 6.90548e-58
Length: 373, Idn/Pos/Gap = 132/207/24 (35%/55%/6%)

Query:  18 EYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGI  77
           +Y   AKA+LP  ++ Y   G+ DE+TL+ N +    +  R RVL D++ + +  ++ G 
Sbjct:   8 DYRAAAKAKLPPFLFHYIDGGSYDERTLKRNTDDLGDVALRQRVLRDMTDLSLETEIFGE  67

Query:  78 DLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFF 137
            L+ P+ +AP  +  M    GE+  A+A  + G    +S+ +   +E+VA  +   P +F
Sbjct:  68 KLAMPIALAPVGLTGMYARRGEVQAAKAAEKKGIPFTMSTVSVCPIEEVAPAIE-RPMWF 126

Query: 138 QLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADI-----------RNQFQLP 186
           QLYV KDR   + ++ RA+ AG   +  TVD P  G R  D+           R  FQ  
Sbjct: 127 QLYVLKDRGFMKNVLERAKAAGVTTLVFTVDMPVPGARYRDMHSGMSGPNAAMRRVFQAM 186

Query: 187 PHLS-------LANFADMKDFAQVKGGAGASGLASYVASL---IDASLNWNDIAWLKSIT 236
            H S       L    D+ + +  +G    + L  Y+  L    D S++W D+ W++   
Sbjct: 187 RHPSWALDVGLLGKPHDLGNISTYRGEP--TKLEDYIGWLGANFDPSISWKDLEWIRDFW 244

Query: 237 RLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVF 296
             P+++KG++  EDA+ A+++GADGI +SNHG RQLDGV +T   L  +A +V+G + +F
Sbjct: 245 DGPMVIKGILDEEDAKDAVRFGADGIVVSNHGGRQLDGVLSTAKALPSIADAVKGDLKIF 304

Query: 297 IDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGC 356
           +DSG+R G DVV+ LALGAD  L+GR  V+ LA  G  GV  LL L   E ++AM L G 
Sbjct: 305 VDSGIRTGLDVVRMLALGADCTLLGRSFVYALAAQGGAGVENLLDLYDKEMRVAMTLTGA 364

Query: 357 QKVSDIRRDLVVR 369
           + ++D+ RD +V+
Sbjct: 365 KTIADLSRDSLVK 377

ref|ZP_00243710.1| COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Rubrivivax gelatinosus PM1]
(370 aa)

Score: 225 bits (574), Expect: 1.61736e-57
Length: 364, Idn/Pos/Gap = 128/196/20 (35%/53%/5%)

Query:  30 MVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGIDLSFPLMVAPTA  89
           M Y Y  SG+  E T R NE  F R+  R RV +++    +   + G D + P+++APT 
Sbjct:   1 MFYDYADSGSWTEGTYRANETDFARILLRQRVAVNMEGRSLRTTLAGQDCAMPVVIAPTG  60

Query:  90 MQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFFQLYVYKDRAITE 149
           +  M H +GE+  ARA    G    LS+ +  S+ED+AAH    P +FQLY  +DR   E
Sbjct:  61 LTGMQHADGEILGARAAEAFGVPFTLSTMSICSIEDIAAHTKA-PFWFQLYWMRDRDFME 119

Query: 150 RLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANFADMKD---------- 199
           RL+ RA+ A   A+ LT+D   LG+R  D++N    PP  +LAN  ++            
Sbjct: 120 RLIERAKAARCSALVLTLDLQVLGQRHKDLKNGMTAPPKPTLANLINLAMKPRWCLGMAG 179

Query: 200 ---------FAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAED 250
                        KG +  S L ++     D  L+W+D+AW+K      ++LKG++   D
Sbjct: 180 TRRHSFGNLVGHAKGVSDMSSLGTWTKEQFDPRLSWDDVAWIKQRWGGRLILKGIMEVAD 239

Query: 251 AQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKA 310
           A+ A   GAD I +SNHG RQLDG  ++I  L  +A++V  RI V++D G+R G DV+KA
Sbjct: 240 AKLAADSGADAIVVSNHGGRQLDGAPSSIAALPAIAEAVGDRIEVWMDGGIRSGQDVLKA 299

Query: 311 LALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLVVRD 370
           +ALGA   +IGR  ++GL   G+ GV R L ++++E  + M   G   +  + R++++  
Sbjct: 300 VALGARGTMIGRAFLYGLGAMGQAGVTRALEIIRNELDITMAFTGHTDIRRVGREILLNA 359

Query: 371 AFAP 374
              P
Sbjct: 360 PTPP 363

gb|EAA53358.1| hypothetical protein MG07635.4 [Magnaporthe grisea 70-15]
ref|XP_367724.1| hypothetical protein MG07635.4 [Magnaporthe grisea 70-15]
(1634 aa)

Score: 225 bits (573), Expect: 1.80266e-57
Length: 375, Idn/Pos/Gap = 140/202/27 (37%/53%/7%)

Query:   4 KPAVNPATQPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLI  63
           +P   P T  LN++++   AK  L  + + YY+SGA+DE +++D    F R+  RPR+L 
Sbjct: 629 QPIHPPLTSMLNVSDFERAAKKYLSDIGWAYYSSGAEDEISMQDPRRIFNRIALRPRILR 688

Query:  64 DVSRVDITKQVMG--IDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATT 121
            V  +D +    G  I  S P+ + PT + R AH +G+   ARA    G V  + + A  
Sbjct: 689 HVETIDTSCSYFGGRIKSSLPIYITPTGLSRYAHQDGDQCLARACGHEGIVYCMPTTAAH 748

Query: 122 SLEDVAAHVPGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRN 181
                A   P  P  FQLY  +D   T  L+R+ ER G  AI +TVD+P +GRRE D R 
Sbjct: 749 EAVFGARTTPNQPLCFQLYTGRDYDRTRALLRKVERLGAAAIFVTVDSPVIGRRERDDR- 807

Query: 182 QFQLPPHLSLANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPIL 241
                        AD +D     G A +  +     +L++ +L W+D+ WL++ T LP++
Sbjct: 808 ----------IKAADGEDPLFAAGVAKSGSM-----TLLNPTLTWDDLDWLRAATSLPLV 852

Query: 242 LKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEV--------AQSVRGRI 293
           LKGV T EDA  A + G DGI +SNHG R  D   A +  L E+        A   R R 
Sbjct: 853 LKGVQTVEDAVLAHRAGVDGIVLSNHGGRSQDTAQAPMLTLLEIRRHAPHLLAPETRSRF 912

Query: 294 PVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVD-GEEGVYRLLSLLKDEFKLAMQ 352
            VF+D GVRRGTDV+KALALGA AV +GRP ++ +    GE GV RL+ +L+ E +  M 
Sbjct: 913 EVFLDGGVRRGTDVLKALALGASAVGVGRPALYSMTNGWGEAGVRRLIMMLRMEIETNMA 972

Query: 353 LCGCQKVSDIRRDLV 367
           L G  ++ ++  ++V
Sbjct: 973 LAGATRLGEVVPEMV 987

gb|AAG29798.1| dehydrogenase [Streptomyces rishiriensis]
(389 aa)

Score: 225 bits (573), Expect: 1.81776e-57
Length: 378, Idn/Pos/Gap = 141/214/24 (37%/56%/6%)

Query:  12 QPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDIT  71
           +P+++A Y   A+  LP +V+ Y  +GADD  TL  N  AF R   R RVL   +     
Sbjct:  13 RPISIAGYRTAARRVLPDLVWAYVENGADDSVTLAANRSAFARWSLRQRVLRSSAGRKTA  72

Query:  72 KQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVP 131
            +    +L+ P+M+APT +  + H  GELATA   A  G+ + LS+ A+ S+E+VAA  P
Sbjct:  73 ARFGDTELAIPVMIAPTGINGLVHWRGELATACGAAAAGSRIVLSTAASYSVEEVAAASP 132

Query: 132 GLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSL 191
            +  + Q+Y ++DR + + L+ R  R+    + +TVDTP  G RE +      +PP L+ 
Sbjct: 133 -VGHWLQVYPWRDRELMDWLLERGRRSDCPTLVVTVDTPVFGNREPERLQGMSIPPVLTP 191

Query: 192 ANFAD---------------------MKDFAQVKGGAGASGLASYVASLIDASLNWNDIA 230
            +  D                     +   + V+ GA A+ +      ++   L+W+D A
Sbjct: 192 RHVLDAALHPRWAYKVLRHQRVFTGNLVGMSGVRAGALAAKVRR--ERMMAGELDWDDFA 249

Query: 231 WLKSITRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVR 290
            +++  +    +KG++ A+DA+RA+  GADGI +SNHG RQLDG  AT+D L  +A  + 
Sbjct: 250 RVRAQWQGLCYVKGILDADDAERAVSLGADGIIVSNHGGRQLDGAPATLDALPGIADRLA 309

Query: 291 GRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLA 350
            R  V ID G+RRGTDVVKAL LGAD  LIGRP ++GLAV GE GV  +LS+L++E    
Sbjct: 310 HRATVLIDGGIRRGTDVVKALCLGADGCLIGRPALYGLAVGGESGVEHVLSILREEIDRT 369

Query: 351 MQLCGCQKVSDIRRDLVV 368
           + L GC  ++D+ RD ++
Sbjct: 370 LALMGCSDIADLGRDWLI 387

ref|ZP_00275308.1| COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Ralstonia metallidurans CH34]
(361 aa)

Score: 225 bits (573), Expect: 1.92709e-57
Length: 352, Idn/Pos/Gap = 140/205/5 (39%/58%/1%)

Query:  11 TQPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDI  70
           T  ++L +Y      R+   +  Y A  A D  T R+N  AF R+R  PR L+D+S+   
Sbjct:   5 TDTVSLRDYEYRFHERVDPAIRAYIAGAAADAVTQRENGAAFERIRLMPRALVDMSQASA  64

Query:  71 TKQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHV 130
             ++ G  L +P+++APTA  ++ HP+GELAT +  +   T M +S+ A+ +LE+VA   
Sbjct:  65 RSELFGETLDYPILIAPTAYHKLVHPDGELATVQGASLTRTWMTVSTQASVTLEEVA-RA 123

Query: 131 PGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLS 190
              P +FQLY+   R  +  LVRRAE+AG++A+ +T+D    G R  + R  F+LP  +S
Sbjct: 124 STAPLWFQLYMQPRREDSLALVRRAEQAGYKALVVTIDAAVSGIRNVEQRAGFRLPDGVS 183

Query: 191 LANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAED 250
             N A       ++   G+      +A     +  W+DI WL   T LP+L+KG++   D
Sbjct: 184 AVNLAGFAANEPIRASVGSPIFRGMLAH----APTWSDIEWLCGQTTLPVLVKGLLNPAD 239

Query: 251 AQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKA 310
              AL  G  GI +SNHG R LD + ATID L  VA +V G +P+ +D GVRRGTD+VKA
Sbjct: 240 VPAALNAGVSGIIVSNHGGRVLDTLPATIDVLPAVAAAVAGAVPILLDGGVRRGTDIVKA 299

Query: 311 LALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDI 362
           +ALGA AVL+G+P++  LAV G  GV  +L+LL+ E + AM L G   + DI
Sbjct: 300 IALGASAVLLGQPVLHALAVGGMPGVVHMLTLLQTELEAAMALLGRPTLRDI 351

ref|YP_048247.1| L-lactate dehydrogenase [Erwinia carotovora subsp. atroseptica SCRI1043]
emb|CAG73039.1| L-lactate dehydrogenase [Erwinia carotovora subsp. atroseptica SCRI1043]
(386 aa)

Score: 225 bits (573), Expect: 2.043e-57
Length: 371, Idn/Pos/Gap = 135/204/20 (36%/54%/5%)

Query:  18 EYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGI  77
           +Y   A+ RLP  ++ Y   GA  E TLR N      +  R R+L ++S + +  Q+ G 
Sbjct:   8 DYRAAAQRRLPPFLFHYIDGGAYGEHTLRRNTADLADIALRQRILKNMSDLSLETQLFGE  67

Query:  78 DLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFF 137
            L+ P+++AP  +  M    GE+  ARA A+ G    LS+ +   +E+VA  +   P +F
Sbjct:  68 KLAMPVVLAPVGLTGMYARRGEVQAARAAAQKGIPFTLSTVSVCPIEEVAPAI-DRPMWF 126

Query: 138 QLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADI-----------RNQFQLP 186
           QLYV KDR      + RA+ AG + +  TVD P  G R  D            R   Q  
Sbjct: 127 QLYVLKDRGFMRSALERAQAAGVKTLVFTVDMPTPGARYRDAHSGMSGPNAAARRMLQAV 186

Query: 187 PHLSLANFADMK----DFAQVKGGAGA-SGLASYV---ASLIDASLNWNDIAWLKSITRL 238
            H   A    +     D   V    G  + L  Y+   A+  D S++W D+AW++   + 
Sbjct: 187 THPQWAWDVGLNGKPHDLGNVSAYRGKPTTLEDYIGWLAANFDPSISWQDLAWIREFWKG 246

Query: 239 PILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFID 298
           P+++KG++  EDA+ A+++GADGI +SNHG RQLDGV +T   L  +A +V+G I +  D
Sbjct: 247 PMIIKGILDPEDAKEAVRFGADGIVVSNHGGRQLDGVLSTAHALPAIADAVKGDITILAD 306

Query: 299 SGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQK 358
           SG+R G DVV+ +ALGAD V++GR  V+ LA  GE GV  LL+L++ E ++AM L G + 
Sbjct: 307 SGIRSGLDVVRMIALGADGVMLGRAFVYALAAAGEAGVVNLLNLIEKEMRVAMTLTGAKS 366

Query: 359 VSDIRRDLVVR 369
           ++DI  D +V+
Sbjct: 367 IADITSDSLVQ 377

gb|AAQ00798.1| L-lactate dehydrogenase (FMN-dependent) related enzyme [Prochlorococcus marinus subsp. marinus str. CCMP1375]
ref|NP_876145.1| L-lactate dehydrogenase (FMN-dependent) related enzyme [Prochlorococcus marinus subsp. marinus str. CCMP1375]
(390 aa)

Score: 224 bits (572), Expect: 2.47521e-57
Length: 386, Idn/Pos/Gap = 142/204/27 (36%/52%/6%)

Query:   2 VEKPAVNPATQPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRV  61
           V  PAV      +N+++  L A+ RLP MV+ Y  SGAD EQTL  N  AF  + FRPR 
Sbjct:   5 VSSPAV------VNISDLRLLAEKRLPRMVFDYIDSGADREQTLSQNCAAFNEIFFRPRC  58

Query:  62 LIDVSRVDITKQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATT 121
            +     ++T  V+  +   P M+AP    R+ +P+GE+  AR   + GT   LS+ +  
Sbjct:  59 AVATPTCNLTTSVLDQEFQLPFMLAPVGSSRLFYPKGEVVAAREAGKAGTGYTLSTLSGC 118

Query: 122 SLEDVAAHVPGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADI-- 179
            LEDV       P ++QLY+   R +  + ++RA+ AGF AI +T+DTP  G RE D+  
Sbjct: 119 RLEDVK-EATNSPAWYQLYLLGGRDVALKTIQRAKLAGFSAIVVTIDTPVSGLRERDLLN 177

Query: 180 -------RNQFQLPPHLSLANF-----------ADMKDFAQVKGGAGASGLASYVASLID 221
                  RN  ++ P+LS                 +  F  V+   G  G      +L  
Sbjct: 178 GTKELLSRNPIKMLPYLSQMVVKPCWMTQWLGDGGLMSFPNVELEDGPMGYTEIGPALEA 237

Query: 222 ASLNWNDIAWLKSITRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDC 281
           + + W D+ W++      I++KGV   +DA++AL  G D I +SNHGARQLD V  TI  
Sbjct: 238 SVVTWEDLKWIREAWGGKIVVKGVHIGDDARKALALGVDAIVVSNHGARQLDSVAPTIRV 297

Query: 282 LEEVAQSVRGRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLS 341
           L EV ++V G+I V +D G+RRG DV+KAL LGA  VLIGR   +GLA  G  GV R + 
Sbjct: 298 LPEVVKAVNGKIDVLLDGGIRRGGDVIKALCLGAKGVLIGRAYAYGLAAAGGPGVARAIE 357

Query: 342 LLKDEFKLAMQLCGCQKVSDIRRDLV 367
           ++K +    M+L GC  V  +    +
Sbjct: 358 IIKTDVLRTMKLLGCDSVKSLNNSFI 383

gb|EAK81508.1| hypothetical protein UM00123.1 [Ustilago maydis 521]
ref|XP_397738.1| hypothetical protein UM00123.1 [Ustilago maydis 521]
(583 aa)

Score: 224 bits (571), Expect: 3.25981e-57
Length: 363, Idn/Pos/Gap = 130/204/18 (35%/56%/4%)

Query:  14 LNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQ  73
           L+L ++   A+  L    + YY+S ADDE T   N  +F R+ FRPRVL  + +VD + +
Sbjct: 209 LSLDDFERIAETILSDQAWAYYSSAADDEITKAQNRASFNRIVFRPRVLRAIGQVDSSVK 268

Query:  74 VM-----GIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVA- 127
           ++     G   S P+ V+P AM ++ HP+GEL   R       + G+S+ A+  L+++  
Sbjct: 269 LLDSNGKGFTCSIPVYVSPAAMAKLGHPDGELNLTRGAGDAEIIQGISANASVGLDEMLD 328

Query: 128 AHVPGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPP 187
           A   G P  +QLYV KDRA +ER++ + E  G  A+ LTVD P +G+RE D R +     
Sbjct: 329 ARKDGQPVIYQLYVNKDRAASERILEKVEARGVSAVMLTVDAPVMGKRERDRRVK----- 383

Query: 188 HLSLANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVT 247
                   +M             G+A  ++  I+ +L W+DI W +   +LP+ LKG+ T
Sbjct: 384 ----GEEVEMGVNHGKDVKKKGGGVAEAISGYIEPNLTWDDIKWFRKTCKLPLYLKGIQT 439

Query: 248 AEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQ---SVRGRIPVFIDSGVRRG 304
            ED + A+++G +G+ +SNHG R L+   A +D L E+ Q    +  +I VF+D GVRRG
Sbjct: 440 VEDVELAVKHGVEGVVLSNHGGRSLEYAPAALDVLVELRQRRPDLFDKIEVFMDGGVRRG 499

Query: 305 TDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRR 364
           TDV+KA+ALGA AV +GR  ++  +  G+ GV R + +L+DE    MQL G   +  +  
Sbjct: 500 TDVLKAVALGAKAVGLGRSFLFAQSGYGQAGVTRAIQILQDEIHRGMQLLGVSSLDQLTP 559

Query: 365 DLV 367
           +++
Sbjct: 560 EMI 562

gb|EAL22533.1| hypothetical protein CNBB4110 [Cryptococcus neoformans var. neoformans B-3501A]
gb|AAW41524.1| L-lactate dehydrogenase (cytochrome), putative [Cryptococcus neoformans var. neoformans JEC21]
ref|XP_568831.1| L-lactate dehydrogenase (cytochrome), putative [Cryptococcus neoformans var. neoformans JEC21]
(592 aa)

Score: 224 bits (571), Expect: 3.60309e-57
Length: 392, Idn/Pos/Gap = 134/206/50 (34%/52%/12%)

Query:  14 LNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQ  73
           +N+ ++   A+    ++ + YYASGADDE T  +N  +++++ FRPRVL  V++ D +  
Sbjct: 209 VNMRDFEKLAEDMCTSVGWAYYASGADDEFTKNENNTSYQKIHFRPRVLRKVAQADASTT 268

Query:  74 VMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDV-AAHVPG 132
           ++G   + P+M++P AM ++ HP GE+   R  A  G +  +SS+A+ SLE++ AA    
Sbjct: 269 ILGYKSTLPVMISPAAMAKLGHPLGEVNMTRGAANTGIIQCISSFASCSLEEICAARSEN 328

Query: 133 LPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIR--NQFQLPPHLS 190
            P FFQLYV   R +   +++R  R    AI LTVD    G+RE D+R    F+ P   +
Sbjct: 329 QPLFFQLYVNSKRDLAAEVLKRVNRLNLNAILLTVDAAVGGKRERDLRLKGNFEPPKTGA 388

Query: 191 LANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAED 250
                D K            G++  + + +D  L W+DI W++S T+LP+L+KGV T ED
Sbjct: 389 YEKHDDTK------------GVSEAMFAGVDPDLCWDDIKWIRSQTKLPLLIKGVQTVED 436

Query: 251 AQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSV--------RG----------- 291
           A  A + GADG+ +SNHG RQLD     ID L E+ +          RG           
Sbjct: 437 AILAYRMGADGVVLSNHGGRQLDTTHTGIDTLLEIRKHAPYLLRPEYRGPTGVQPAALEH 496

Query: 292 ----------------RIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEG 335
                              +++D G+ RG+D VKAL LGA+AV  GR  ++  AV G++G
Sbjct: 497 PENLTPPDPQEKPTDRPFEIWVDGGIWRGSDAVKALCLGANAVGSGRGFLFANAVGGQKG 556

Query: 336 VYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLV 367
           V   +++   E    M+L G  KV  +R  +V
Sbjct: 557 VEHAVNIFSAEILTTMRLLGVNKVDQLRPSMV 588

gb|AAW79575.1| MdlB [Pseudomonas fluorescens]
(397 aa)

Score: 223 bits (568), Expect: 8.09411e-57
Length: 370, Idn/Pos/Gap = 146/213/31 (39%/57%/8%)

Query:  13 PLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITK  72
           PLN+A+Y   A+ RLP MV+ Y   GA+DEQ L+ N E F+ +RF+PR L+DVS+ D++ 
Sbjct:   6 PLNVADYRELARRRLPKMVFDYLEGGAEDEQGLQHNREVFQNVRFKPRRLMDVSQRDLST  65

Query:  73 QVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPG 132
            + G   S PL++ PT +     PEG+LA ARA +R G    LS+ +  S+ED+A    G
Sbjct:  66 SLFGKRQSLPLLIGPTGLNGALWPEGDLALARAASRAGIPFVLSTASNLSIEDLARRCDG 125

Query: 133 LPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLP------ 186
              +FQLYV   R + E++V RA  AG++ + LT D    G RE D+RNQF++P      
Sbjct: 126 -ELWFQLYVVH-RTLAEQMVERALAAGYKTLVLTTDVAVNGYRERDLRNQFKMPMSYTPR 183

Query: 187 --------PHLSL----ANFADMKDFAQVKGGAGASGL---ASYVASLIDASLNWNDIAW 231
                   P  SL        ++ +F   +    AS L   A+ ++  +DAS +W  + W
Sbjct: 184 VMLDGCLHPRWSLDLVRHGMPELANFVSSE----ASSLEVQAALMSRQMDASFDWQALRW 239

Query: 232 LKSITRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRG 291
           L+      +L+KG++ A+DA R +  G DG+ +SNHG RQLD     I   E +A++VR 
Sbjct: 240 LRDKWPHTLLVKGLLDADDAARCIAEGVDGVILSNHGGRQLD---TAISPFEVLAETVRK 296

Query: 292 RIPVFID-SGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLA 350
             P   D +G RRG D+VKALA+GA+AVL+GR  ++GLA  GE GV  +L LLK +    
Sbjct: 297 VSPPSTDRTGFRRGADIVKALAMGANAVLLGRATLYGLAARGEAGVDDVLRLLKADIDRT 356

Query: 351 MQLCGCQKVS 360
           +   GC  ++
Sbjct: 357 LAQIGCPSIA 366

gb|EAA60189.1| hypothetical protein AN4424.2 [Aspergillus nidulans FGSC A4]
ref|XP_408561.1| hypothetical protein AN4424.2 [Aspergillus nidulans FGSC A4]
(494 aa)

Score: 223 bits (568), Expect: 8.29927e-57
Length: 369, Idn/Pos/Gap = 129/207/15 (34%/56%/4%)

Query:   3 EKPAVNPATQPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVL  62
           +KP   P    +N  ++   A        + +Y+S A D  T   N+  F R+ FRPRVL
Sbjct: 105 DKP---PLETLINSHDFEYVASRTASKKTWAFYSSAATDLITRDANKSCFDRIWFRPRVL 161

Query:  63 IDVSRVDITKQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTS 122
            +V  VD   +++G+D S PL V+P AM ++ H +GE A ARA    G + G+S+ ++ +
Sbjct: 162 RNVRSVDTKSKILGVDSSIPLFVSPAAMAKLIHRDGECAIARACESRGIMQGISNNSSYT 221

Query: 123 LEDVAAHVPGLPKFFQLYVYKDRAITERLVRR-AERAGFRAIALTVDTPQLGRREADIRN 181
           +E++    PG   FFQLYV ++R  +  L+R+ +     +AI +TVD    G+READ R 
Sbjct: 222 MEELKDSAPGANFFFQLYVNREREKSAALLRKCSANPNIKAIFVTVDAAWPGKREADERV 281

Query: 182 QFQLPPHLSLANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPIL 241
           +      + +A        +Q +  +   GL   +A  ID  L W D+ W++  T LP+ 
Sbjct: 282 KADESLSVPMAP-------SQARNDSKGGGLGRVMAGFIDPGLTWEDLVWVRKHTHLPVC 334

Query: 242 LKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQ---SVRGRIPVFID 298
           LKGV++A+DA  A++ G DGI +SNHG R LD    +I  L E+ +    +  R+ +++D
Sbjct: 335 LKGVMSADDAILAMEAGLDGILLSNHGGRNLDTSPPSIITLLELHKRCPEIFDRMEIYVD 394

Query: 299 SGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQK 358
           SG+RRGTD++KA+ LGA AV +GR +++     G+ GV  L+ +++DE + AM+  G   
Sbjct: 395 SGIRRGTDILKAICLGATAVGMGRSMLFATNY-GQAGVEHLIDIMRDELETAMRNIGITS 453

Query: 359 VSDIRRDLV 367
           + +    LV
Sbjct: 454 LDEAGPHLV 462

ref|YP_070106.1| L-lactate dehydrogenase [Yersinia pseudotuberculosis IP 32953]
ref|NP_669900.1| L-lactate dehydrogenase [Yersinia pestis KIM]
gb|AAS61696.1| L-lactate dehydrogenase [Yersinia pestis biovar Medievalis str. 91001]
ref|NP_992819.1| L-lactate dehydrogenase [Yersinia pestis biovar Medievalis str. 91001]
emb|CAH20817.1| L-lactate dehydrogenase [Yersinia pseudotuberculosis IP 32953]
emb|CAC90391.1| L-lactate dehydrogenase [Yersinia pestis CO92]
gb|AAM86151.1| L-lactate dehydrogenase [Yersinia pestis KIM]
ref|NP_405152.1| L-lactate dehydrogenase [Yersinia pestis CO92]
pir||AD0191 L-lactate dehydrogenase (cytochrome) (EC 1.1.2.3) [imported] - Yersinia pestis (strain CO92)
(381 aa)

Score: 222 bits (566), Expect: 1.16845e-56
Length: 367, Idn/Pos/Gap = 130/200/20 (35%/54%/5%)

Query:  18 EYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGI  77
           +Y   A+ +LP  ++ Y   GA +EQTLR N      +  R RVL ++S + +  Q+ G 
Sbjct:   8 DYRAAAQRKLPPFLFHYIDGGAYNEQTLRRNTADLADIALRQRVLKNMSELSLETQLFGE  67

Query:  78 DLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFF 137
             + P+++ P  +  M    GE+  ARA  + G    LS+ +   +E+VA  +   P +F
Sbjct:  68 TQAMPVVLGPVGLSGMYARRGEVQAARAADKKGIPFTLSTLSVCPIEEVAPAI-ARPMWF 126

Query: 138 QLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREAD-----------IRNQFQLP 186
           QLYV KDR      + RA+ AG + +  TVD P  G R  D            R   Q  
Sbjct: 127 QLYVLKDRGFMRNALTRAQAAGVKTLVFTVDMPVPGARYRDAHSGMSGPNAAARRLLQAI 186

Query: 187 PHLSLANFADMK----DFAQVKGGAGA----SGLASYVASLIDASLNWNDIAWLKSITRL 238
            H   A    +     D   +    G          ++A+  D S++W D+ W++   + 
Sbjct: 187 AHPQWAWDVGLNGKPHDLGNISAYLGKPTTLEDYMGWIATNFDPSISWKDLEWVREFWQG 246

Query: 239 PILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFID 298
           P+++KG++  EDA+ A+++GADGI +SNHG RQLDGV +T   L  +A +V+G I +  D
Sbjct: 247 PMIIKGILDPEDAKDAVKFGADGIVVSNHGGRQLDGVLSTARALPAIADAVKGDITILAD 306

Query: 299 SGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQK 358
           SG+R G DVV+ +ALGAD+VL+GR  V+ LA  GE GV  LL+L++ E ++AM L G ++
Sbjct: 307 SGIRTGLDVVRMIALGADSVLLGRAFVYALATAGEAGVINLLTLIEQEMRVAMTLTGAKR 366

Query: 359 VSDIRRD 365
           ++DI RD
Sbjct: 367 IADINRD 373

gb|EAA58787.1| hypothetical protein AN7984.2 [Aspergillus nidulans FGSC A4]
ref|XP_412121.1| hypothetical protein AN7984.2 [Aspergillus nidulans FGSC A4]
(503 aa)

Score: 221 bits (564), Expect: 1.92765e-56
Length: 405, Idn/Pos/Gap = 145/222/24 (35%/54%/5%)

Query:   5 PAVNPATQPL-NLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLI  63
           PA  P    + NL E+   AKA L    + YY S AD   +   N   + ++  RPR+L 
Sbjct: 102 PAPTPHLHTVQNLNEFESIAKACLSPNAWAYYNSAADSLASFHKNLTDWSKIALRPRILR 161

Query:  64 DVSRVDITKQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWAT--- 120
           +VS+V + + +MG   S P+ +APTA  ++ HP+GE+  ARA AR   +  +SS+A+   
Sbjct: 162 NVSKVSLGRTIMGHRSSLPVFIAPTARAKLGHPDGEVCLARAAARHNILYAVSSYASIGH 221

Query: 121 -----------TSLEDVAAHVPGLPKFFQLYVYKDRAITER-LVRRAERAGFRAIALTVD 168
                      T L  ++A        FQLY+  D+    R L+ +A+  GF+A+ +TVD
Sbjct: 222 AELAEEFVKEKTRLVPISARSAQGALGFQLYLPYDKERGGRALIAKAKDLGFQALVVTVD 281

Query: 169 TPQLGRREADIRNQFQLPPHLSLANFADMKDFAQVKGGAGASGLASYVASLIDASLNWND 228
           TP +G+READ R  FQ    +  ++ A ++    V   A   G A  +     +SL W+D
Sbjct: 282 TPVVGKREADER--FQAELEVISSDRAAVQ--VNVPRKAEPGGDAPVLRGFHSSSLEWDD 337

Query: 229 IAWLK-SITRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQ 287
           I W++ +    P+++KG+ TAEDA RA + G DGI++SNHG RQLD   ++I  L E+ +
Sbjct: 338 IPWIREAWGPQPLIIKGIQTAEDALRASEAGIDGIYLSNHGGRQLDYAPSSIQTLLEINR 397

Query: 288 ---SVRGRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLK 344
               V  R+ V++D GVRRGTDV+KA+ LGA  V +GRP+++ L+  G  GV + L +L 
Sbjct: 398 FCPEVLKRVEVYLDGGVRRGTDVIKAICLGAKGVGLGRPLLYALSGYGTGGVDKALQILS 457

Query: 345 DEFKLAMQLCGCQKVSDIRRDLVVRDAFAPYDVRQMLSVKMQSKL 389
           DE + +++L G   VS++    V   A     V   L +K  S +
Sbjct: 458 DEIETSLRLMGVVDVSELDLSFVNTTALEKDLVSSFLHLKDYSSI 502

ref|ZP_00166458.2| COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Ralstonia eutropha JMP134]
(397 aa)

Score: 221 bits (562), Expect: 3.78916e-56
Length: 376, Idn/Pos/Gap = 142/197/24 (37%/52%/6%)

Query:  15 NLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQV  74
           N+AE    A ARLP     Y   GADDE TL  N  ++  + F PR L+DVS  D    +
Sbjct:  18 NIAELRAMASARLPNFCLEYLEGGADDELTLHRNRASYDAIAFTPRTLVDVSVRDPGCTL  77

Query:  75 MGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLP 134
            G  +  P ++APT    +   EG+LA A A    G  M  S  +T +LE VA    G+ 
Sbjct:  78 FGQRIEMPAVIAPTGFNGLLTHEGDLALAHAARDAGIPMCQSMVSTVALERVAE--TGVR 135

Query: 135 KFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANF 194
            + Q+Y +KD      +VRRAE AG  AI +T D P LG RE D RN ++ P  L +AN 
Sbjct: 136 HWMQIYPFKDHENLAGIVRRAEAAGSEAIVVTTDVPVLGNREWDRRN-YRAPMKLDVANL 194

Query: 195 AD----------------MKDFAQV-----KGGAGASGLASYVASLIDASLNWNDIAWLK 233
            +                M  F  +      G   A   A++++  +D SLNW D+ WL+
Sbjct: 195 INVALRPKWWWDVLVPHGMPHFRNLGDILPPGQDDARNAATFLSRQMDPSLNWQDVQWLR 254

Query: 234 SITRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRI 293
            +    ++LKG+V  +DA RA   G D + I+NHG RQLD   A I+ L E+  +V   +
Sbjct: 255 DLWPRKLILKGIVRPDDALRARALGVDALVITNHGGRQLDSCVAPIEVLPEIRAAVGPDM 314

Query: 294 PVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQL 353
            + +DSG+RRG D VKA ALGADA + GR  ++GLA  G  GV   L++L+ E    + L
Sbjct: 315 TLIVDSGLRRGGDFVKARALGADAAMSGRATLYGLAAGGRTGVAHALAILRAEIDRTLGL 374

Query: 354 CGCQKVSDIRRDLVVR 369
            GC  ++D+  D V R
Sbjct: 375 LGCPALTDLGPDCVSR 390

ref|NP_420209.1| L-lactate 2-monooxygenase [Caulobacter crescentus CB15]
gb|AAK23377.1| L-lactate 2-monooxygenase [Caulobacter crescentus CB15]
pir||E87422 L-lactate 2-monooxygenase [imported] - Caulobacter crescentus
(391 aa)

Score: 220 bits (561), Expect: 5.51578e-56
Length: 358, Idn/Pos/Gap = 138/201/9 (38%/56%/2%)

Query:  13 PLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITK  72
           P++       A A +   +  Y   G  DE T R N +AF      PR+++D S+ D++ 
Sbjct:  24 PVDFKTLEARATAAMSPDLLSYVQGGCGDEFTQRRNADAFHDWGVVPRMMVDASKRDLSI  83

Query:  73 QVMGIDLSFPLMVAPTAMQRMAHPEG--ELATARAVARIGTVMGLSSWATTSLEDVAAHV 130
           ++ G+ L  PL ++P  +  M   +G  ++ATA A  R G  +  S+ A   +E V A +
Sbjct:  84 ELFGLKLPTPLFMSPIGVIGMCAQDGHGDIATAVAAQRTGVPVMASTLANDPIEKVGAAL 143

Query: 131 PGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIR--NQFQLPPH 188
                FFQLY  KDR + E L+RRAE AGF+A+ +T+DT   G R  D+   N  QL  H
Sbjct: 144 GDGVGFFQLYTPKDRDLAESLIRRAETAGFKALVVTLDTWVTGWRPRDLNDANFPQLRGH 203

Query: 189 LSLANFADMKDFAQVKGGAGASGLASYVAS---LIDASLNWNDIAWLKSITRLPILLKGV 245
           +    F D + F ++ G   A   A+ + +   L   +L W D+AWL+S T+LPI+LKG+
Sbjct: 204 VLQNYFTDPR-FLEILGKPVAEDPATAIRTWGGLFGKTLTWEDLAWLRSATKLPIVLKGI 262

Query: 246 VTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGT 305
              +DA+RA+  G DG++ SNHG RQ +G  A ID LE+V  +  G  PV  DSGVR G+
Sbjct: 263 CHPDDARRAVDLGVDGVFCSNHGGRQANGGIAAIDLLEDVV-TASGNTPVLFDSGVRSGS 321

Query: 306 DVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIR 363
           D  KALA+GA AV IGRP  +GLA+ G +GV  +L  +  E  L M + G   ++ +R
Sbjct: 322 DAAKALAMGARAVGIGRPYAYGLAIGGVDGVVHVLRSILAELDLLMAVDGFPTLAALR 379

gb|EAK86222.1| hypothetical protein UM04746.1 [Ustilago maydis 521]
ref|XP_402361.1| hypothetical protein UM04746.1 [Ustilago maydis 521]
(451 aa)

Score: 220 bits (560), Expect: 6.85207e-56
Length: 289, Idn/Pos/Gap = 116/176/10 (40%/60%/3%)

Query:   6 AVNPATQPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDV  65
            V P +Q LNL ++ + AK  L    + YY+SGADDE T+R+N  AF R+ FRPR+L DV
Sbjct: 100 GVPPLSQCLNLYDFEVIAKRVLKPTAWAYYSSGADDEVTMRENTSAFGRIWFRPRILRDV 159

Query:  66 SRVDITKQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLED 125
           S+VD +  ++G   + P+ +  TA+ ++ HPEGE     A  + G +  + + A+ S ++
Sbjct: 160 SKVDYSTSLLGQKSTLPIYITATALGKLGHPEGEKNLTVAAGKEGIIQMIPTLASCSFDE 219

Query: 126 -VAAHV-PGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQF 183
            V A +     +F QLYV  +R +TE ++++AE AG + + +TVD PQLGRRE D+R +F
Sbjct: 220 IVGARINDSQVQFLQLYVNSNRKVTENIIQKAEAAGVKGLFVTVDAPQLGRREKDMRMKF 279

Query: 184 QLPPHLSLANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLK 243
                       D  D +Q        G A  ++S ID SL+W+D+ WL+S+T++PI+LK
Sbjct: 280 DDVGSDHQNKNKDNVDRSQ--------GAARAISSFIDPSLSWDDLTWLRSVTKMPIVLK 331

Query: 244 GVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGR 292
           GV T EDA RA + G  G+ +SNHG RQLD   + I+ L EV ++++ R
Sbjct: 332 GVQTWEDAVRAAELGLSGVVLSNHGGRQLDFARSGIEVLGEVVEALKAR 380

ref|XP_327648.1| hypothetical protein [Neurospora crassa]
gb|EAA28754.1| hypothetical protein [Neurospora crassa]
(520 aa)

Score: 219 bits (558), Expect: 1.01422e-55
Length: 373, Idn/Pos/Gap = 137/198/16 (36%/53%/4%)

Query:   3 EKPAVNPATQPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVL  62
           EK A  P    LN  E    AK ++    + YY S ADD  T   N  AFR +  RPRV 
Sbjct: 118 EKAAPPPLHTLLNFDEIEAAAKTQVSKKCWSYYFSAADDLYTKTHNTRAFRDILLRPRVF 177

Query:  63 IDVSRVDITKQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTS 122
           ID ++ D +  ++G  +  PL V+P A+ R+AHP+GE   A+ ++  G +  +S+ A+ +
Sbjct: 178 IDCTKADTSTTLLGHKVGTPLYVSPAALARLAHPDGEAGIAKGISSFGAMQLVSNNASMT 237

Query: 123 LEDVAAH-VPGLPKFFQLYVYKDRAITERLVRRAE--RAGFRAIALTVDTPQLGRREADI 179
            E + A  +PG    +QLYV   R+ +E ++ R    R  F+ I LT+D P  G+RE D 
Sbjct: 238 PEQIVAEAIPGAVFGWQLYVQTTRSKSEAMLARINKLRDHFKCIVLTLDAPHPGKREHDE 297

Query: 180 RNQFQLPPHLSLANFADMKDFAQVKGGAGASGLASYVASLIDASLNW-NDIAWLKSITRL 238
           ++  +      + + ++ K  A+ K G G  G   +  +  D  L W   + WL   T L
Sbjct: 298 KSNLEAAGEF-VESASNAKTDAEKKPGGGGVGQQLFWGTAAD--LTWETTLPWLSKHTDL 354

Query: 239 PILLKGVVTAEDAQRALQYG------ADGIWISNHGARQLDGVTATIDCLEEVAQ---SV 289
           PI+LKG+ T EDA  A QY          I +SNHG R LD     +  L E+ +    V
Sbjct: 355 PIVLKGIQTHEDAYLAAQYARKHPGTVKAIILSNHGGRALDTAPPAVHTLLEIRKYCPEV 414

Query: 290 RGRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKL 349
            G + V+ID GV+RGTDVVKAL LGA AV +GR  +WGL   G +GV R   +L+ E   
Sbjct: 415 FGAVEVWIDGGVKRGTDVVKALCLGAKAVGVGRAALWGLGAGGWQGVERTFDILQQEIIT 474

Query: 350 AMQLCGCQKVSDI 362
            M+L G + V+D+
Sbjct: 475 CMKLLGAKTVNDL 487

gb|EAL18665.1| hypothetical protein CNBI3650 [Cryptococcus neoformans var. neoformans B-3501A]
gb|AAW45177.1| L-mandelate dehydrogenase, putative [Cryptococcus neoformans var. neoformans JEC21]
ref|XP_572484.1| L-mandelate dehydrogenase, putative [Cryptococcus neoformans var. neoformans JEC21]
(555 aa)

Score: 219 bits (558), Expect: 1.09332e-55
Length: 363, Idn/Pos/Gap = 125/197/11 (34%/54%/3%)

Query:   4 KPAVNPATQPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLI  63
           + ++ P    L L ++  + +  L    + YY S AD E T  +N +AFRR   RPR+L 
Sbjct: 177 RKSLPPVDTMLLLQDFEDWGQQVLSGTAWAYYRSAADSENTFHENTDAFRRYWLRPRILR 236

Query:  64 DVSRVDITKQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSL 123
            V++ D     +GID   P+ ++P AM ++ HP GE+   R   R G V  +S+ A+  L
Sbjct: 237 KVAQGDTKTSFLGIDTETPIFISPAAMAKLGHPLGEVNLTRGAGRAGIVQAISANASCGL 296

Query: 124 EDV-AAHVPGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQ 182
           +++  A   G    +Q+Y+ KDR  +E L+++ E+    A+  TVD P   +R  D R +
Sbjct: 297 DEIMEAREEGQKVIYQIYLNKDRKASEVLLQKVEKLKPAAVMFTVDVPWQSKRTMDTRAK 356

Query: 183 FQLPPHLSLANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILL 242
             + P +     ++ K  A +       G++  +    D  L+W DIA+++    +PI++
Sbjct: 357 NTVNPPIQDTAGSEKKSRAPL-------GVSEAIGGYQDRDLSWEDIAFIRKYISVPIIV 409

Query: 243 KGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEV---AQSVRGRIPVFIDS 299
           KGV + ED +  ++ GA+G+ ISNHG R  D   A ID L E+      +  +I V ID 
Sbjct: 410 KGVQSVEDIELCVKAGAEGVLISNHGGRSCDYAPAPIDILYELRCHRPELFNQIDVLIDG 469

Query: 300 GVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKV 359
           GVR G DVVKALALGA AV +GRP ++     G+EGV R+  +L++E    M+  G  KV
Sbjct: 470 GVRTGADVVKALALGAKAVGVGRPFLYANGTHGQEGVERVCEILQEEITNTMRNAGATKV 529

Query: 360 SDI 362
           S++
Sbjct: 530 SEL 532

emb|CAG15041.1| HmO protein [Actinoplanes teichomyceticus]
emb|CAE53379.1| Hmo protein [Actinoplanes teichomyceticus]
(364 aa)

Score: 219 bits (557), Expect: 1.34691e-55
Length: 347, Idn/Pos/Gap = 148/200/2 (42%/57%/0%)

Query:  18 EYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGI  77
           ++ L A+A L A V  + A G+D E TL  N  A  R+   PRVL      +    + G 
Sbjct:  13 DFRLRAEATLTAAVRDFVAGGSDSETTLAANRAALDRVTIVPRVLTGGPDPEPGATLAGA  72

Query:  78 DLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFF 137
             + PL VAP A QR+ HPEGELATARA A  G    +S+ ++  + ++AA   G  ++F
Sbjct:  73 RSALPLAVAPMAYQRLLHPEGELATARAAAAAGVPFVVSTLSSVPVGELAA--AGGEQWF 130

Query: 138 QLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANFADM 197
           QLY   D   T  LV RAE AG R + +TVD P +GRR  DIRN+F LP  +  AN A  
Sbjct: 131 QLYWLNDDRDTMNLVHRAEDAGCRVLMVTVDVPVMGRRLRDIRNEFVLPAEVRAANVASG 190

Query: 198 KDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQRALQY 257
              A        S L ++       +L W  +  L+S T LPI++KG++   DA+RA + 
Sbjct: 191 AMSAAHDRADAGSALIAHTNRAFHPALTWAHLEALRSRTTLPIVVKGILDPADARRAAEI 250

Query: 258 GADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALALGADA 317
           GA G+ ISNHG RQLDG  A++  L     +V     VF+DSG+R GTD+++ALALGA  
Sbjct: 251 GATGVVISNHGGRQLDGAPASVTMLPAAVAAVPDTCQVFVDSGIRSGTDILRALALGAHG 310

Query: 318 VLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRR 364
           VLIGRP++WGLA  GE G   +L++L  E + AM+L GC  V+  RR
Sbjct: 311 VLIGRPMLWGLAAGGETGAAGVLAVLDAELRAAMRLAGCADVAAARR 357

pir||I39549 Lactate oxidase - Aerococcus viridans
dbj|BAA09172.1| lactate oxidase [Aerococcus viridans]
(374 aa)

Score: 218 bits (555), Expect: 2.16713e-55
Length: 342, Idn/Pos/Gap = 121/190/10 (35%/55%/2%)

Query:  23 AKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGIDLSFP  82
           A   +P   + Y A  + DE T R N+ A++     PR+  DV   D + +++G  +  P
Sbjct:  29 ASKVVPHGGFNYIAGASGDEWTKRANDRAWKHKLLYPRLAQDVEAPDTSTEILGHKIKAP  88

Query:  83 LMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFFQLYVY 142
            ++AP A   +AH   E  TARAV+  GT+M +S+++  + E+++  + G P++FQ+Y+ 
Sbjct:  89 FIMAPIAAHGLAHTTKEAGTARAVSEFGTIMSISAYSGATFEEISEGLNGGPRWFQIYMA 148

Query: 143 KDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANFADMKDFAQ 202
           KD      ++  A+  G  AI LT D+   G R+ D++N+F  P  + +           
Sbjct: 149 KDDQQNRDILDEAKSDGATAIILTADSTVSGNRDRDVKNKFVYPFGMPIVQ-------RY 201

Query: 203 VKGGAGASGLAS-YVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQRALQYGADG 261
           ++G A    L + Y AS     ++  DI  +   + LP+ +KG+   EDA  A++ GA G
Sbjct: 202 LRGTAEGMSLNNIYGAS--KQKISPRDIEEIAGHSGLPVFVKGIQHPEDADMAIKRGASG 259

Query: 262 IWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALALGADAVLIG 321
           IW+SNHGARQL     + D L  +A+ V  R+P+  DSGVRRG  V KALA GAD V +G
Sbjct: 260 IWVSNHGARQLYEAPGSFDTLPAIAERVNKRVPIVFDSGVRRGEHVAKALASGADVVALG 319

Query: 322 RPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIR 363
           RP+++GLA+ G +G Y +L   + +    MQL G Q V D++
Sbjct: 320 RPVLFGLALGGWQGAYSVLDYFQKDLTRVMQLTGSQNVEDLK 361

gb|AAQ19817.1| putative L-lactate dehydrogenase [Alcaligenes faecalis]
(379 aa)

Score: 218 bits (555), Expect: 2.25945e-55
Length: 373, Idn/Pos/Gap = 129/203/22 (34%/54%/5%)

Query:  18 EYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGI  77
           +Y   A+ RLP  ++ Y   GA  E TLR N +    +  R RVL D+S++D +  + G 
Sbjct:   8 DYRRAAQKRLPPFLFHYIDGGAYAEHTLRRNVDDLAEVALRQRVLKDMSQLDTSIDLFGE  67

Query:  78 DLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFF 137
            LS P+ ++P  +  M    GE+  ARA    G    +SS +   +E+VA  +   P +F
Sbjct:  68 KLSMPVALSPVGLTGMYARRGEVQAARAADARGIPFTMSSVSVCPIEEVAPRL-SRPMWF 126

Query: 138 QLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANFA-- 195
           QLYV KDR      + RA+ AG   +  TVD P  G R  D  +     P+ +L  +A  
Sbjct: 127 QLYVLKDRGFMRNALERAQAAGCSTLVFTVDMPVPGARYRDAHSGMS-GPNAALRRYAQA 185

Query: 196 -----------------DMKDFAQVKGG-AGASGLASYVASLIDASLNWNDIAWLKSITR 237
                            D+ + ++  G   G      Y+ +  D S++W D+ W++   +
Sbjct: 186 VMHPRWAWDVGLLGRPHDLGNISRYLGKPTGLEDYMGYLGANFDPSISWKDLEWIREFWK 245

Query: 238 LPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFI 297
            P+L+KG++  +DA+ A+++GADGI +SNHG RQLDGV ++   L  +A +V+G+I +  
Sbjct: 246 GPMLIKGILDPDDARDAVRFGADGIIVSNHGGRQLDGVLSSARALPAIADAVKGQIKILA 305

Query: 298 DSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQ 357
           DSG+R G DVV+ +ALGADA ++GR  ++ LA  G+ GV  LL L++ E ++AM L    
Sbjct: 306 DSGIRSGLDVVRMIALGADAAMLGRAYIYALAAAGQSGVDHLLGLIEKEIRVAMTLTSVS 365

Query: 358 KVSDIRRDLVVRD 370
            +S I  +L+VR+
Sbjct: 366 SISQITSELLVRE 378

ref|NP_773041.1| L-lactate dehydrogenase [Bradyrhizobium japonicum USDA 110]
dbj|BAC51666.1| L-lactate dehydrogenase [Bradyrhizobium japonicum USDA 110]
(394 aa)

Score: 218 bits (555), Expect: 2.73746e-55
Length: 373, Idn/Pos/Gap = 136/202/23 (36%/54%/6%)

Query:  13 PLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITK  72
           P+ + +Y   AK RLP MV+ Y   GA+ E++L  N  AF  + F PR L+DVS  + + 
Sbjct:  25 PVCIDDYRSLAKRRLPRMVFDYLDGGAESERSLHRNLGAFAAINFAPRRLVDVSHRNSSV  84

Query:  73 QVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPG 132
            + G  L  P +VAPT +     P+G++A ARA    G    LS+ +  ++EDVA    G
Sbjct:  85 SLFGRTLPTPFVVAPTGLNGALWPDGDVALARAARSAGIPFVLSTASNATIEDVAERAGG 144

Query: 133 LPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLP------ 186
              +FQLYV + R +   LV RA+ AG+R + LTVD    G+R+ D+RN F +P      
Sbjct: 145 -DLWFQLYVVQ-RDLARLLVGRAKEAGYRVLVLTVDVAVNGKRDRDLRNGFAIPFRQTPR 202

Query: 187 --------PHLSLAN----FADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKS 234
                   P  +L         + +FA        +  A+ +   +DAS  W D+  L+ 
Sbjct: 203 SVLDAVTHPRWALGQIRHGLPQLANFAS-PDATDVNAQAALMRRQMDASFCWQDLQALRD 261

Query: 235 ITRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIP 294
                +++KG++TA D  R  + G D + +SNHG RQ++ V A ID L E++   +  +P
Sbjct: 262 AWPGRLIVKGIMTATDVNRCRELGVDAVVLSNHGGRQIEDVQAPIDLLAEISN--QNAMP 319

Query: 295 VFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLC 354
           + +D G+RRG D VKALALGA AVL+GR I++GLA  GEEG   +L +L  EF   + L 
Sbjct: 320 LLVDGGIRRGADAVKALALGAKAVLLGRAILYGLAAAGEEGAGHVLQILTAEFDTTLALV 379

Query: 355 GCQKVSDIRRDLV 367
           GC   + + R  +
Sbjct: 380 GCPDPARLNRQFI 392

gb|AAB36100.1| L-lactate oxidase, LOX [Aerococcus viridans, IFO12219, Peptide, 371 aa]
(371 aa)

Score: 218 bits (554), Expect: 2.97566e-55
Length: 342, Idn/Pos/Gap = 121/191/10 (35%/55%/2%)

Query:  23 AKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGIDLSFP  82
           A   +P   + Y A  + DE T R N+ A++     PR+  DV   D + +++G  +  P
Sbjct:  26 ASKVVPHGGFNYIAGASGDEWTKRANDRAWKHKLLYPRLAQDVEAPDTSTEILGHKIKAP  85

Query:  83 LMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFFQLYVY 142
            ++AP A   +AH   E  TARAV+  GT+M +S+++  + E+++  + G P++FQ+Y+ 
Sbjct:  86 FIMAPIAAHGLAHTTKEAGTARAVSEFGTIMSISAYSGATFEEISEGLNGGPRWFQIYMA 145

Query: 143 KDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANFADMKDFAQ 202
           KD      ++  A+  G  AI LT D+   G R+ D++N+F  P  + +           
Sbjct: 146 KDDQQNRDILDEAKSDGATAIILTADSTVSGNRDRDVKNKFVYPFGMPIVQ-------RY 198

Query: 203 VKGGAGASGLAS-YVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQRALQYGADG 261
           ++G A    L + Y AS     ++  DI  + + + LP+ +KG+   EDA  A++ GA G
Sbjct: 199 LRGTAEGMSLNNIYGAS--KQKISPRDIEEIAAHSGLPVFVKGIQHPEDADMAIKAGASG 256

Query: 262 IWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALALGADAVLIG 321
           IW+SNHGARQL     + D L  +A+ V  R+P+  DSGVRRG  V KALA GAD V +G
Sbjct: 257 IWVSNHGARQLYEAPGSFDTLPAIAERVNKRVPIVFDSGVRRGEHVAKALASGADVVALG 316

Query: 322 RPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIR 363
           RP+++GLA+ G +G Y +L   + +    MQL G Q V D++
Sbjct: 317 RPVLFGLALGGWQGAYSVLDYFQKDLTRVMQLTGSQNVEDLK 358

ref|NP_746844.1| L-lactate dehydrogenase [Pseudomonas putida KT2440]
gb|AAN70308.1| L-lactate dehydrogenase [Pseudomonas putida KT2440]
(381 aa)

Score: 216 bits (551), Expect: 7.57586e-55
Length: 374, Idn/Pos/Gap = 134/206/24 (35%/55%/6%)

Query:  18 EYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGI  77
           +Y   A+ +LP  ++ Y   GA  E TLR N      +  R RVL ++S + +  ++   
Sbjct:   8 DYRAAAQRKLPPFLFHYADGGAYAEHTLRHNVSDLAGIALRQRVLNNMSELSLETKLFDE  67

Query:  78 DLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFF 137
            LS P+ +AP  +  M    GE+  ARA A  G    +S+ +   +E+VA  +   P +F
Sbjct:  68 TLSMPVALAPVGLTGMYARRGEVQAARAAAAHGIPFTMSTVSVCPIEEVAPAI-NRPMWF 126

Query: 138 QLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREAD-----------IRNQFQLP 186
           QLYV KDR      + RA+ AG + +  TVD P  G R  D           +R   Q  
Sbjct: 127 QLYVLKDRGFMRNALERAKAAGVKTLVFTVDMPVPGARYRDAHSGMSGKNGPLRRVLQAM 186

Query: 187 PHLSLA-------NFADMKDFAQVKGGAGASGLASYVASL---IDASLNWNDIAWLKSIT 236
            H   A          D+ + ++ +G    +GLA Y+  L    D S++W D+ W++   
Sbjct: 187 THPEWAWDVGVMGRPHDLGNISKYRGNP--TGLADYIGWLGNNFDPSISWKDLEWIREFW 244

Query: 237 RLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVF 296
             P+++KG++ A+DA+ A+++GADGI +SNHG RQLDGV ++   L  +A +V+G + + 
Sbjct: 245 DGPMIIKGILDADDARDAVKFGADGIVVSNHGGRQLDGVLSSARALPAIADAVKGDLKIL 304

Query: 297 IDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGC 356
            DSG+R G DVV+ +ALGAD VLIGR  ++ LAV G+ GV  LL L + E ++AM L G 
Sbjct: 305 ADSGIRSGLDVVRMIALGADTVLIGRAFLYALAVHGQAGVKNLLELFEKEMRVAMVLTGA 364

Query: 357 QKVSDIRRDLVVRD 370
           + +S+I RD +VR+
Sbjct: 365 KSISEITRDSLVRE 378

gb|AAF96880.1| L-lactate dehydrogenase [Vibrio cholerae O1 biovar eltor str. N16961]
ref|NP_233368.1| L-lactate dehydrogenase [Vibrio cholerae O1 biovar eltor str. N16961]
pir||B82392 L-lactate dehydrogenase VCA0984 [imported] - Vibrio cholerae (strain N16961 serogroup O1)
(378 aa)

Score: 216 bits (549), Expect: 1.14022e-54
Length: 373, Idn/Pos/Gap = 127/206/24 (34%/55%/6%)

Query:  18 EYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGI  77
           +Y   AKA+LP  ++ Y   G+  E TLR N +    +  R RVL D+S + +  ++ G 
Sbjct:   8 DYRAAAKAKLPPFLFHYIDGGSYGEHTLRRNTDDLADIALRQRVLSDMSELSLETELFGE  67

Query:  78 DLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFF 137
            ++ P+ ++P  +  M    GE+  A+A    G    LS+ +   +E+VA  +   P +F
Sbjct:  68 KMALPIALSPVGLTGMYARRGEVQAAQAAEAKGIPFTLSTVSVCPIEEVAPSI-HRPIWF 126

Query: 138 QLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADI-----------RNQFQLP 186
           QLYV KDR   + ++ RA+ AG + +  TVD P  G R  D+           R   Q  
Sbjct: 127 QLYVLKDRGFMKNVLERAKAAGVKNLVFTVDMPVPGARYRDMHSGMSGPNAAMRRVLQAM 186

Query: 187 PHLS-------LANFADMKDFAQVKGGAGASGLASYVASL---IDASLNWNDIAWLKSIT 236
            H S       L    D+ + ++ +G    + L  Y+  L    D S++W D+ W++   
Sbjct: 187 AHPSWAWDVGLLGKPHDLGNISKYRGSP--TKLEDYIGWLGANFDPSISWKDLEWIRDFW 244

Query: 237 RLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVF 296
             P+++KG++  EDA+ A+++GADGI +SNHG RQLDGV +T+  L  +A +V+G + + 
Sbjct: 245 DGPMIIKGILDTEDAKDAVRFGADGIVVSNHGGRQLDGVLSTVQALPAIADAVKGDLKIL 304

Query: 297 IDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGC 356
           +DSG+R G DVV+ LALGAD  ++GR  ++ LA  G  GV  LL L + E ++AM L G 
Sbjct: 305 VDSGIRTGLDVVRMLALGADCTMLGRSFIYALAAQGRAGVENLLDLYEKEMRVAMTLTGA 364

Query: 357 QKVSDIRRDLVVR 369
           + ++++ RD +V+
Sbjct: 365 KSIAELSRDSLVK 377

ref|ZP_00134489.1| COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Actinobacillus pleuropneumoniae serovar 1 str. 4074]
(381 aa)

Score: 216 bits (549), Expect: 1.31399e-54
Length: 370, Idn/Pos/Gap = 133/195/20 (35%/52%/5%)

Query:  18 EYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGI  77
           +Y   A+ R+P  ++ Y   G+  E+TL  N      L  R RVL D+S++D   ++ G 
Sbjct:   8 DYREAARRRVPPFMFHYADGGSFSERTLERNVTDLADLALRQRVLKDMSQLDTEIELFGE  67

Query:  78 DLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFF 137
            L+ P ++AP     M    GE+  A+A    G    LS+ +   +E+V A +   P +F
Sbjct:  68 KLAMPAVLAPVGACGMYARRGEVQAAQAAENKGIPFTLSTVSICPIEEVTAAIK-RPMWF 126

Query: 138 QLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREAD-----------IRNQFQLP 186
           QLYV KDR   + ++ RA+ AG   +  TVD P  G R  D           IR   Q  
Sbjct: 127 QLYVLKDRGFMKHVLERAKAAGCSTLVFTVDMPTPGARYRDRHSGMSGDYKEIRRALQAV 186

Query: 187 PHLSLANFADMKDFAQVKGGAGA-----SGLASYVASL---IDASLNWNDIAWLKSITRL 238
            H   A    +K      G   A      GL  YV  L    D S++W D+ W++     
Sbjct: 187 THPFWAWDVGIKGKPHTLGNVSAYTGKAVGLDDYVVWLGENFDPSISWKDLEWIRDFWDG 246

Query: 239 PILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFID 298
           P+++KG++  EDA+ A+++GADGI +SNHG RQLDG  ++   L  +A +V+G I +  D
Sbjct: 247 PMVIKGILDPEDAKDAVRFGADGIVVSNHGGRQLDGALSSARALPSIADAVKGDIKILAD 306

Query: 299 SGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQK 358
           SG+R G D+V+ LALGADA ++GR  V+ L   G+ GV  +L + K E  +AM L   QK
Sbjct: 307 SGIRNGLDIVRMLALGADATMLGRAFVYALGAAGKAGVENMLDIFKKEMHVAMTLTSNQK 366

Query: 359 VSDIRRDLVV 368
           +SDI RD +V
Sbjct: 367 ISDITRDALV 376

gb|EAA73452.1| hypothetical protein FG03984.1 [Gibberella zeae PH-1]
ref|XP_384160.1| hypothetical protein FG03984.1 [Gibberella zeae PH-1]
(429 aa)

Score: 215 bits (548), Expect: 1.71612e-54
Length: 395, Idn/Pos/Gap = 136/217/41 (34%/54%/10%)

Query:  17 AEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSR--------V  68
           + +   AK  L A  +GY    A +  T ++N  +F R    P  L+   +         
Sbjct:  33 SRWESLAKETLSATSWGYIHGNAGNASTYQNNINSFSRWSIIPNRLVPSRKDENGNEQFA  92

Query:  69 DITKQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAA 128
           D T +V+G  L FP+ +AP  +Q++ +PEGE ATARA   +G    LS+ ++TS+EDVAA
Sbjct:  93 DTTTKVLGQTLPFPVAIAPIGVQKIFNPEGEAATARAATSLGIPYTLSTASSTSIEDVAA 152

Query: 129 -HVPGLPKFFQLYVYKDRA---ITERLVRRAERAGFRAIALTVDTPQLGRREADIRN--- 181
            +    P++FQLY +  R    IT  +++RA+ +G+ A+ +T+DT  LG R +D+ N   
Sbjct: 153 ANGKNAPRWFQLY-WPSREHDDITISMLKRAKESGYTALFVTLDTYVLGWRPSDLDNGYN 211

Query: 182 QFQLPPHLSLA---------------NFADMKD-----FAQVKGGAGASGL---ASYVAS 218
            F  P H+ +                +  D+ D     +   +GG+  +GL   A   A 
Sbjct: 212 PFIHPDHIGVEIGLTDPVFKKQFKEEHGYDITDAPSGVYQAAQGGSTGAGLGVAAREWAK 271

Query: 219 LI--DASLNWNDIAWLKSITRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVT 276
           ++    S +W DI +LK     PI+LKG+ + +DA++ ++ G  GI +SNHG RQ DG  
Sbjct: 272 IVFPGHSHSWEDIEFLKKHWDGPIVLKGIQSVQDAKKCVEVGVQGIVVSNHGGRQQDGGV 331

Query: 277 ATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGV 336
           +++  L  +  +V   I V  DSG+R G D++KALALGA  VL+GRP  +GLA+ GE+GV
Sbjct: 332 SSLGMLPRIVDAVGDNIDVLFDSGIRCGADIMKALALGAKCVLVGRPYTYGLALGGEDGV 391

Query: 337 YRLLSLLKDEFKLAMQLCGCQKVSDIRRDLVVRDA 371
             +L  L  +  + M L G + +S++ RD++V++A
Sbjct: 392 RHVLRALCGDLTMNMHLAGLRNISEVTRDILVKEA 426

gb|AAM35025.1| L-lactate dehydrogenase [Xanthomonas axonopodis pv. citri str. 306]
ref|NP_640489.1| L-lactate dehydrogenase [Xanthomonas axonopodis pv. citri str. 306]
(388 aa)

Score: 214 bits (544), Expect: 4.67075e-54
Length: 385, Idn/Pos/Gap = 138/207/30 (35%/53%/7%)

Query:  17 AEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMG  76
           ++Y   A+ARLP  ++ Y   GA  E TLR N      +  R RVL ++S + ++ ++ G
Sbjct:   7 SDYRAAAEARLPPFLFHYIDGGAYAEHTLRRNVSDLADVALRQRVLRNMSDLRLSTELFG  66

Query:  77 IDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKF 136
             L+ P+ +AP  +  M    GE+  ARA A  G    LS+ +   +E+VA  +   P +
Sbjct:  67 ETLAMPVALAPVGLTGMYARRGEVQAARAAAARGIPFTLSTVSVCPIEEVAPAIE-RPMW 125

Query: 137 FQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRR-----------EADIRNQFQL 185
           FQLYV KDR      + RA+ AG   +  TVD P  G R            A +R   Q 
Sbjct: 126 FQLYVLKDRGFMRNALERAKAAGVTTLVFTVDMPTPGARYRDAHSGMSGPNASLRRMLQA 185

Query: 186 PPHLS-------LANFADMKDFAQVKGGAGASGLASYVASL---IDASLNWNDIAWLKSI 235
             H         L    D+ + +  +G    +GL  Y+  L    D S+ W D+ W++  
Sbjct: 186 VTHPRWAWDVGLLGKPHDLGNISAYRGSP--TGLQDYIGWLGANFDPSIAWKDLEWIREF 243

Query: 236 TRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPV 295
              P+++KG++  EDA+ A+++GADGI +SNHG RQLDGV ++   L  +A +V+G + +
Sbjct: 244 WTGPMVIKGILDPEDARDAVRFGADGIVVSNHGGRQLDGVLSSARALPAIADAVKGELKI 303

Query: 296 FIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCG 355
             DSG+R G DVV+ LALGADAVL+GR  V+ LA  G+ GV  LL+L++ E ++AM L G
Sbjct: 304 LADSGIRSGLDVVRMLALGADAVLLGRAFVYALAAAGQAGVENLLTLIEKEMRVAMTLTG 363

Query: 356 CQKVSDIRRDLVVR------DAFAP 374
              ++DI  D + R      DA +P
Sbjct: 364 THSIADISADALSRVTRERADAISP 388

ref|NP_635501.1| L-lactate dehydrogenase [Xanthomonas campestris pv. campestris str. ATCC 33913]
gb|AAM39425.1| L-lactate dehydrogenase [Xanthomonas campestris pv. campestris str. ATCC 33913]
(386 aa)

Score: 213 bits (543), Expect: 5.24949e-54
Length: 374, Idn/Pos/Gap = 135/205/24 (36%/54%/6%)

Query:  17 AEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMG  76
           ++Y   A+ARLP  ++ Y   GA  E TLR N      +  R RVL ++S + ++ ++ G
Sbjct:   7 SDYRAAAEARLPPFLFHYIDGGAYAEHTLRRNVSDLADIALRQRVLRNMSDLSLSTELFG  66

Query:  77 IDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKF 136
             L+ P+ +AP  +  M    GE+  ARA A  G    LS+ +   +E+VA  +   P +
Sbjct:  67 ETLAMPVALAPVGLTGMYARRGEVQAARAAAARGIPFTLSTVSVCPIEEVAPAI-DRPMW 125

Query: 137 FQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRR-----------EADIRNQFQL 185
           FQLYV KDR      + RA+ AG   +  TVD P  G R            A +R   Q 
Sbjct: 126 FQLYVLKDRGFMRNALERAKTAGVTTLVFTVDMPTPGARYRDAHSGMSGPNASLRRMLQA 185

Query: 186 PPHLS-------LANFADMKDFAQVKGGAGASGLASYV---ASLIDASLNWNDIAWLKSI 235
             H         L    D+ + +  +G    +GL  Y+   A+  D S++W D+ W++  
Sbjct: 186 MTHPRWAWDVGLLGKPHDLGNISTYRGSP--TGLQDYIGWLAANFDPSISWKDLEWIREF 243

Query: 236 TRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPV 295
              P+++KG++  EDA+ A+++GADGI +SNHG RQLDGV ++   L  +A +V+G + +
Sbjct: 244 WTGPMVIKGILDPEDARDAVRFGADGIVVSNHGGRQLDGVLSSARALPAIADAVKGELKI 303

Query: 296 FIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCG 355
             DSG+R G DVV+ LALGADAVL+GR  V+ LA  G+ GV  LL+L++ E ++AM L G
Sbjct: 304 LADSGIRSGLDVVRMLALGADAVLLGRAFVYALAAGGQAGVENLLTLIEREMRVAMILTG 363

Query: 356 CQKVSDIRRDLVVR 369
              V++I  D + R
Sbjct: 364 THSVAEISGDALSR 377

emb|CAE31607.1| FMN-dependent dehydrogenase [Bordetella bronchiseptica RB50]
ref|NP_887655.1| FMN-dependent dehydrogenase [Bordetella bronchiseptica RB50]
(397 aa)

Score: 213 bits (543), Expect: 6.10018e-54
Length: 346, Idn/Pos/Gap = 138/203/23 (39%/58%/6%)

Query:  32 YGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGIDLSFPLMVAPTAMQ  91
           + Y   GA+D +TLR N  A+ +L F PRVL DVS VD    V+G +   P++V PT + 
Sbjct:  30 FDYLEGGAEDGRTLRRNLAAYGKLVFNPRVLTDVSAVDTRVPVLGREQHSPMIVGPTGLN  89

Query:  92 RMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFFQLYVYKDRAITERL 151
            +  P  + A ARA    G    LS+ +T+ +EDV A   G   + QLYV  DR+I E +
Sbjct:  90 GLYWPRADEALARAAHAAGLPFVLSTASTSLIEDVRAASAG-DLWLQLYVQTDRSIAETM 148

Query: 152 VRRAERAGFRAIALTVDTPQLGRREADIRNQFQLP----PHLSLANFA------------ 195
           +RRA  A F  + +TVDTP  G R+ D+RN F+LP    P L L +FA            
Sbjct: 149 MRRAREARFSTLMVTVDTPVHGTRDHDVRNGFRLPLRPGPRLML-DFAAHPRWCLRMLRQ 207

Query: 196 ----DMKDFAQVKG-GAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAED 250
                + + A+  G  A  +  A+ ++  +D  L W+ + WL+   + P+L+KG+++ ED
Sbjct: 208 RGGPQLVNLARSMGEQASLNRQAAAMSRQMDMGLGWDALPWLRRHWQGPVLVKGILSVED 267

Query: 251 AQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKA 310
           A+ AL++GADGI +SNHG RQL+G  + ++ L  V  +V  R+ V +D GVRRG+DV KA
Sbjct: 268 ARLALRHGADGIVLSNHGGRQLEGAPSALEVLPRVMDAVGTRLAVLVDGGVRRGSDVAKA 327

Query: 311 LALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGC 356
            ALGA AVL+GR  ++GLA  G  GV  +L++L+ E +  ++L GC
Sbjct: 328 RALGAQAVLLGRAPLYGLAARGPRGVAEVLAILQRELETTLRLVGC 373

ref|YP_198661.1| L-lactate dehydrogenase [Xanthomonas oryzae pv. oryzae KACC10331]
gb|AAW73276.1| L-lactate dehydrogenase [Xanthomonas oryzae pv. oryzae KACC10331]
(388 aa)

Score: 213 bits (542), Expect: 7.14812e-54
Length: 374, Idn/Pos/Gap = 134/202/24 (35%/54%/6%)

Query:  17 AEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMG  76
           ++Y   A+ARLP  ++ Y   GA  E TLR N      +  R RVL ++S + ++ ++ G
Sbjct:   7 SDYRAAAQARLPPFLFHYIDGGAYAEHTLRRNVSDLADVALRQRVLRNMSDLRLSTELFG  66

Query:  77 IDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKF 136
             L+ P+ + P  +  M    GE+  ARA A  G    LS+ +   +E+VA  +   P +
Sbjct:  67 ETLAMPVALGPVGLTGMYARRGEVQAARAAAARGIPFTLSTVSVCPIEEVAPAIE-RPMW 125

Query: 137 FQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRR-----------EADIRNQFQL 185
           FQLYV KDR      + RA+ AG   +  TVD P  G R            A +R   Q 
Sbjct: 126 FQLYVLKDRGFMRNALERAKAAGVTTLVFTVDMPTPGARYRDAHSGMSGPNASLRRMLQA 185

Query: 186 PPHLS-------LANFADMKDFAQVKGGAGASGLASYVASL---IDASLNWNDIAWLKSI 235
             H         L    D+ + +  +G    +GL  Y+  L    D S+ W D+ W++  
Sbjct: 186 VTHPRWAWDVGVLGKPHDLGNISAYRGNP--TGLQDYIGWLGANFDPSIAWKDLEWIREF 243

Query: 236 TRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPV 295
              P+++KG++  EDA+ A+++GADGI +SNHG RQLDGV ++   L  +A +V+G + +
Sbjct: 244 WTGPMVIKGILDPEDARDAVRFGADGIVVSNHGGRQLDGVLSSARALPAIADAVKGELKI 303

Query: 296 FIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCG 355
             DSG+R G DVV+ LALGADAVL+GR  V+ LA DG+ GV  LL+L++ E ++AM L G
Sbjct: 304 LADSGIRSGLDVVRMLALGADAVLLGRAFVYALAADGQAGVENLLTLIEKEMRVAMTLTG 363

Query: 356 CQKVSDIRRDLVVR 369
              ++ I  D + R
Sbjct: 364 THSIAQISADALSR 377

gb|EAA60537.1| hypothetical protein AN8744.2 [Aspergillus nidulans FGSC A4]
ref|XP_412881.1| hypothetical protein AN8744.2 [Aspergillus nidulans FGSC A4]
(403 aa)

Score: 213 bits (542), Expect: 7.57805e-54
Length: 370, Idn/Pos/Gap = 125/203/13 (33%/54%/3%)

Query:  23 AKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGIDLSFP  82
           A+  L  + Y Y A GA ++ T+  N  AFR+ +  P++L  + + DI+  + G D   P
Sbjct:  36 ARKALSDIAYNYVAGGAGEKATMDSNRLAFRQWKLIPKMLRKMDKQDISVNLFGQDYPTP  95

Query:  83 LMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFFQLYVY 142
           L++AP  +Q + HP+ E   A   A  G    LS+ +T+S+E+VA       ++FQLY  
Sbjct:  96 LIMAPVGVQGLFHPDKETGLAEVCAETGVPYTLSTASTSSIEEVANASGDGKRWFQLYWP 155

Query: 143 KDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANFADMKD--- 199
            D  IT  LV+RA+  G+  + +T+DT  L  R AD+ N + +P    + N     D   
Sbjct: 156 GDDDITLSLVKRAKENGYSVLVVTLDTWSLSWRPADLDNAY-IPFIRGIGNQVGFSDPVF 214

Query: 200 ---FAQVKGGAGASGLASYVASLIDASLN-----WNDIAWLKSITRLPILLKGVVTAEDA 251
              F +  G      +     + I   L+     W+++++L+     P++LKG+   EDA
Sbjct: 215 RAKFEKESGSKVEDDIVGASRAWISKVLSTTPHVWDEVSFLRKHWDGPLVLKGIQHVEDA 274

Query: 252 QRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKAL 311
           + AL+ G DGI +SNHG RQ+DG  A+++ L E+  +V  ++ V  DSG+R G D++KAL
Sbjct: 275 KLALEAGCDGIVVSNHGGRQVDGAIASLEVLPEIVDAVGDKLTVLFDSGIRTGADIIKAL 334

Query: 312 ALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLVVRDA 371
            LGA  VL+GRP+++GL++DG+ G   ++  L+ +   +M L G   V++  RD  +R  
Sbjct: 335 CLGAKGVLVGRPVIYGLSIDGKNGAKAVIKGLQADLWQSMSLSGICTVAECTRD-KIRKI 393

Query: 372 FAPYDVRQML 381
             P D + ML
Sbjct: 394 QYPGDTKAML 403

ref|NP_962420.1| hypothetical protein MAP3486 [Mycobacterium avium subsp. paratuberculosis str. k10]
gb|AAS06036.1| hypothetical protein MAP3486 [Mycobacterium avium subsp. paratuberculosis str. k10]
(392 aa)

Score: 213 bits (542), Expect: 7.90089e-54
Length: 366, Idn/Pos/Gap = 134/188/5 (36%/51%/1%)

Query:   8 NPATQPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSR  67
           N    P+   E    A A +   V GY A GA DE T R N EAF+R    PR+ I   +
Sbjct:  18 NQPQYPIRFEELEAKASAAMTPKVLGYVAGGAGDEHTQRANCEAFKRWGLYPRMGIAPEQ  77

Query:  68 VDITKQVMGIDLSFPLMVAPTAMQRMAHPEG--ELATARAVARIGTVMGLSSWATTSLED 125
            D++ ++ G     P+ +AP  +  +  P+G  +LA  RA  R G    + + +   +ED
Sbjct:  78 RDMSVELFGTRFPSPIFMAPIGVIGVCDPDGHGDLACVRASIRTGVPFFVGTLSADPMED 137

Query: 126 VAAHVPGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRN-QFQ 184
           +A  +   P FFQLY   DR +   LV RAE A F  IA+T+DT   G R  D+    + 
Sbjct: 138 LADELGDTPAFFQLYTPPDRKMAASLVHRAEAASFSGIAVTLDTWVTGWRPRDLSGGNYP 197

Query: 185 LPPHLSLANFADMKDF-AQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLK 243
             P   LAN+     F A +  G   +  A     +      W D+ WL+S T LP++ K
Sbjct: 198 QVPSGCLANYTSDPVFRAGLSRGEDPTEAAVRKLPIFGGPFRWEDLEWLRSRTSLPLMAK 257

Query: 244 GVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRR 303
           G+   +D +RA   G D ++ SNHG RQ +G    +DCL  V ++  G +PV  DSGVR 
Sbjct: 258 GICHPDDVRRAKDIGVDAVYCSNHGGRQANGGLPCLDCLPGVVEAADG-LPVLFDSGVRS 316

Query: 304 GTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIR 363
           G D+VKALALGA AV IGRP  +GLA+ G +G+  +L  L  E  L M + G   + D+ 
Sbjct: 317 GADIVKALALGATAVGIGRPYAYGLALGGVDGIVHVLRSLLAEADLIMAVDGYPSLKDLT 376

Query: 364 RDLVVR 369
            D + R
Sbjct: 377 PDALRR 382

ref|NP_771463.1| L-lactate dehydrogenase [Bradyrhizobium japonicum USDA 110]
dbj|BAC50088.1| L-lactate dehydrogenase [Bradyrhizobium japonicum USDA 110]
(377 aa)

Score: 213 bits (542), Expect: 8.73292e-54
Length: 373, Idn/Pos/Gap = 133/189/33 (35%/50%/8%)

Query:   1 MVEKPAVNP--------ATQPL-NLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEA  51
           M EKP + P        +++P  NL E+   A+A L    + Y    A+ E T+R N  A
Sbjct:   1 MNEKPRIQPERNVELGASSEPFQNLHEFIRKARANLNQNAWDYIVGAAETETTMRRNRMA  60

Query:  52 FRRLRFRPRVLIDVSRVDITKQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGT 111
              + FRPRVL DV +VD + +  G  +  P+++AP     +  P+G  + ARA    G 
Sbjct:  61 LDEIAFRPRVLRDVRKVDGSVEQFGRRMRLPVVLAPVGALEIFDPDGAASVARAAGTFGA 120

Query: 112 VMGLSSWATTSLEDVAAHVPGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQ 171
              LSS +   LE  AA  P   + +QLYV  D A    +V RAE+  + A  LTVDT  
Sbjct: 121 AHMLSSVSEPGLEKTAAAAPDALRLYQLYVRGDDAFVADVVSRAEKHAYAAFCLTVDTAH 180

Query: 172 LGRREADIRNQFQLPPHLSLANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAW 231
             RRE DI  ++     L            +  GG    GL             W  +  
Sbjct: 181 YSRRERDIAKRYVRESRL------------RATGGDFQKGL------------EWRTVKM 216

Query: 232 LKSITRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRG 291
           +K   ++P++LKG+ TAEDA  AL +G + I++SNHG RQLD     +  L E+ ++V+G
Sbjct: 217 IKDKFKIPLILKGIATAEDALIALDHGVEWIYVSNHGGRQLDHGRGAMHVLPEIVEAVKG 276

Query: 292 RIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAM 351
           R  + +D G  RGTD+VKA+A GAD V IGR   W LA  GE GV R+L LL+DE    +
Sbjct: 277 RAKIMVDGGFGRGTDIVKAIAAGADLVGIGRLQCWALAAAGEAGVTRMLELLEDEVLRCL 336

Query: 352 QLCGCQKVSDIRR 364
            L G    +++ +
Sbjct: 337 GLLGATSFAEVNK 349

ref|YP_111804.1| putative dehydrogenase [Burkholderia pseudomallei K96243]
emb|CAH39276.1| putative dehydrogenase [Burkholderia pseudomallei K96243]
ref|YP_105096.1| FMN-dependent dehydrogenase [Burkholderia mallei ATCC 23344]
gb|AAU46217.1| FMN-dependent dehydrogenase [Burkholderia mallei ATCC 23344]
(412 aa)

Score: 213 bits (541), Expect: 1.12168e-53
Length: 370, Idn/Pos/Gap = 139/201/22 (37%/54%/5%)

Query:  15 NLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDV-SRV-DITK  72
           N+ +    A+ R+P   + Y   GA+ E T+R NE  F R R R +VL    SRV  +  
Sbjct:   9 NIDDLRKMARKRVPKYFFDYLDGGANSETTMRANENDFARWRLRQKVLTGAQSRVAGLGA  68

Query:  73 QVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPG 132
             +G +   P+++ P     M    GE+A  RA    G    LS+++  SLEDVAA   G
Sbjct:  69 TYLGAEHRLPILLGPVGFAGMYWSRGEIAAGRAADDAGIGQCLSTFSICSLEDVAAARSG 128

Query: 133 LPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLA 192
            P +FQLY+++DR +TE ++ R   A   A+ LTVDT  +  RE D RN F+    LS  
Sbjct: 129 -PLYFQLYMFRDRDLTEDILARCRLANVDAVFLTVDTCYIPIRERDARNGFRADTRLSAR 187

Query: 193 NFADMKDFAQVKGGAGASGL-------------------ASYVASLIDASLNWNDIAWLK 233
               M        GA + G+                   ++ V  +I+  L+W D+ WL+
Sbjct: 188 GVWSMLKRPGWCAGALSHGVPRIGNVLRYPELGASLLEQSAAVGRMIETRLSWADVKWLR 247

Query: 234 SITRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRI 293
           +     I++KG++  +DA+RA+  G DGI ISNHG RQLD   + +D L E+A++V  R 
Sbjct: 248 ARWPGRIVIKGILDPDDARRAVDEGVDGILISNHGGRQLDPAPSVMDVLPEIAEAVGKRT 307

Query: 294 PVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQL 353
            + +D GVRRG DV+KALALGA AV IGR  V+GL   GE+GV R L LLK E   A+ +
Sbjct: 308 EILMDGGVRRGADVIKALALGASAVSIGRAYVYGLGAAGEKGVSRCLELLKGEMLPALNM 367

Query: 354 CGCQKVSDIR 363
            G + ++++R
Sbjct: 368 MGFESIAELR 377

ref|YP_044908.1| L-lactate dehydrogenase, FMN linked [Acinetobacter sp. ADP1]
emb|CAG67086.1| L-lactate dehydrogenase, FMN linked [Acinetobacter sp. ADP1]
(384 aa)

Score: 212 bits (540), Expect: 1.17926e-53
Length: 370, Idn/Pos/Gap = 123/200/20 (33%/54%/5%)

Query:  18 EYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGI  77
           +Y   AK RLP  ++ Y   GA  E TL+ N E   ++  R RVL D+S + +  ++   
Sbjct:   8 DYREAAKRRLPPFLFHYIDGGAYAEYTLKRNVEDLSQIALRQRVLNDMSSLSLETKLFNE  67

Query:  78 DLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFF 137
            LS P+ ++P  +  M    GE+  A A  + G    +S+ +   +E+V   +   P +F
Sbjct:  68 TLSMPVALSPVGLTGMYARRGEVQAAVAADKKGIPFTMSTVSVCPIEEVTPAIK-RPMWF 126

Query: 138 QLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRN-------------QFQ 184
           QLYV +DR   +  + RA+ AG   +  TVD P  G R  D  +             Q  
Sbjct: 127 QLYVLRDRGFMKNALERAKAAGCSTLVFTVDMPVPGARYRDAHSGMSGPNAAMRRYLQSM 186

Query: 185 LPPHLS-----LANFADMKDFAQVKGGA-GASGLASYVASLIDASLNWNDIAWLKSITRL 238
           + P  +     L    D+ + ++  G   G     S++ S  D S++W D+ W++     
Sbjct: 187 MHPQWAWDVGLLGRPHDLGNISKYLGKTTGLEDYISWLGSNFDPSISWKDLEWIREFWDG 246

Query: 239 PILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFID 298
           P+++KG++  EDA+ A+++GADGI +SNHG RQLDGV ++   +  +A++V+G + +  D
Sbjct: 247 PMVIKGILDPEDAKDAVRFGADGIVVSNHGGRQLDGVMSSARAMPAIAEAVKGDLTILAD 306

Query: 299 SGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQK 358
           SG+R G DVV+ LALGAD+V++GR  ++ LA  G +GV  LL L+  E ++AM L G + 
Sbjct: 307 SGIRNGLDVVRMLALGADSVMLGRAFIYALAAQGGQGVSNLLDLIDKEMRVAMTLTGAKT 366

Query: 359 VSDIRRDLVV 368
           ++DI    +V
Sbjct: 367 IADINESCLV 376

gb|EAL21230.1| hypothetical protein CNBD2850 [Cryptococcus neoformans var. neoformans B-3501A]
gb|AAW43255.1| conserved hypothetical protein [Cryptococcus neoformans var. neoformans JEC21]
ref|XP_570562.1| conserved hypothetical protein [Cryptococcus neoformans var. neoformans JEC21]
(552 aa)

Score: 212 bits (540), Expect: 1.48961e-53
Length: 358, Idn/Pos/Gap = 127/193/13 (35%/53%/3%)

Query:  14 LNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQ  73
           L + ++  +A+  +    + YY S AD E+T  +NE+AF R  FRPR+L D +      +
Sbjct: 186 LLVQDFEDWAEKVMSGTAWNYYKSAADREKTAAENEKAFDRYFFRPRILRDATTGSTETE 245

Query:  74 VMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDV-AAHVPG 132
            MG+  + P+ ++P AM ++ +P GE+   R     G V G+S  A+ SL+++  A   G
Sbjct: 246 FMGMKTTMPVFISPAAMAKLGNPLGEVNLTRGAGACGIVQGISINASCSLDEIMTARKEG 305

Query: 133 LPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLA 192
            P  FQ+Y+ KDRA +  L++R    G  AI  TVDT    +R  D+R +  + P  S +
Sbjct: 306 QPVMFQIYLNKDRAASIALLKRVTALGANAIIFTVDTAWRSKRTMDVRAKAHVAPPPSSS 365

Query: 193 NFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQ 252
                    Q K  A   G++  ++   D +L W DI +++  T LPI++KGV   ED  
Sbjct: 366 --------GQQK-SASPLGVSQAISGYQDTNLTWKDIDFIREHTNLPIIVKGVQCVEDVD 416

Query: 253 RALQYGADGIWISNHGARQLDGVTATIDCLEEV---AQSVRGRIPVFIDSGVRRGTDVVK 309
              + G  G+ +SNHG RQ D   A ID L E+      +  +I V +D GVR G DVVK
Sbjct: 417 LCAKAGVQGVILSNHGGRQCDYAPAPIDLLYELRCKRPDLFDKIEVMMDGGVRSGADVVK 476

Query: 310 ALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLV 367
           A+ALGA AV IGR  ++     GEEGV RL  +L +E    M+  G  ++ D++ ++V
Sbjct: 477 AIALGAKAVGIGRSFLYANGTHGEEGVVRLCQILAEEITNTMRNIGAPRLEDLKPEMV 534

ref|NP_439882.1| L-lactate dehydrogenase LctD [Haemophilus influenzae Rd KW20]
gb|AAC23385.1| L-lactate dehydrogenase (lctD) [Haemophilus influenzae Rd KW20]
pir||T09429 L-lactate dehydrogenase (EC 1.1.1.27) - Haemophilus influenzae (strain Rd)
sp|P46454|LLDD_HAEIN L-lactate dehydrogenase (Cytochrome)
(381 aa)

Score: 212 bits (539), Expect: 1.68821e-53
Length: 371, Idn/Pos/Gap = 128/195/20 (34%/52%/5%)

Query:  17 AEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMG  76
           ++Y   A+ R+P  ++ Y   G+  EQTL  N      +  R RVL D+S +D + ++ G
Sbjct:   7 SDYREAARRRVPPFMFHYADGGSYAEQTLARNVSDLENIALRQRVLKDMSELDTSIELFG  66

Query:  77 IDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKF 136
             LS P ++AP     M    GE+  A+A    G    LS+ +   +E+VA  +   P +
Sbjct:  67 EKLSMPTILAPVGACGMYARRGEVQAAQAADNKGVPFTLSTVSICPIEEVAPAIK-RPMW 125

Query: 137 FQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREAD-----------IRNQFQL 185
           FQLYV KDR   +  + RA+ AG   +  TVD P  G R  D           IR   Q 
Sbjct: 126 FQLYVLKDRGFMKNALERAKAAGCSTLVFTVDMPTPGARYRDMHSGMSGPYKEIRRVLQG 185

Query: 186 PPHLSLANFADMKDFAQVKGGAGAS-----GLASYVASL---IDASLNWNDIAWLKSITR 237
             H   A    +K      G          GL  Y+  L    D S++W D+ W++    
Sbjct: 186 FTHPFWAYDVGIKGKPHTLGNVSTYMGRQIGLDDYIGWLTENFDPSISWKDLEWIREFWE 245

Query: 238 LPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFI 297
            P+++KG++  EDA+ A+++GADGI +SNHG RQLDGV ++   L  +A +V+G I +  
Sbjct: 246 GPMVIKGILDPEDAKDAVRFGADGIVVSNHGGRQLDGVLSSARALPPIADAVKGDIKIIA 305

Query: 298 DSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQ 357
           DSG+R G D+V+ LALGADA ++GR  V+ L  +G +GV  +L + K E  +AM L   +
Sbjct: 306 DSGIRNGLDIVRMLALGADATMLGRAFVYALGAEGRQGVENMLDIFKKEMHVAMTLTSNR 365

Query: 358 KVSDIRRDLVV 368
            ++DI+ + +V
Sbjct: 366 TIADIKPEALV 376

ref|YP_191585.1| Putative oxidoreductase [Gluconobacter oxydans 621H]
gb|AAW60929.1| Putative oxidoreductase [Gluconobacter oxydans 621H]
(381 aa)

Score: 212 bits (539), Expect: 1.70236e-53
Length: 366, Idn/Pos/Gap = 132/191/19 (36%/52%/5%)

Query:  16 LAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVM  75
           +A  H  A   LP +   Y   G+  E+T+R N  AF R    P+ L+DVS  D++   +
Sbjct:   6 IAALHRRADRVLPRIFRDYVNGGSHSERTVRANRRAFERWAVVPKCLVDVSDCDLSGSFL  65

Query:  76 GIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPK 135
           G     P M AP     +  P+GE+  AR  A  G  M +S++A  SLE ++  VPG+  
Sbjct:  66 GATHRLPFMFAPLGFGGLMCPDGEIRAARVAASAGLPMAVSTFAIQSLETLS-RVPGVTL 124

Query: 136 FFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANFA 195
             Q+YV++DR IT  ++RRAE  G R I LTVDTP    R  D+RN F+     SL +  
Sbjct: 125 AAQIYVFRDRGITRDMLRRAESCGIRNIILTVDTPITPLRLRDVRNGFRNLTRPSLRHVL 184

Query: 196 DMKDFAQVKGGAGASGL------------------ASYVASLIDASLNWNDIAWLKSITR 237
            M    +   G   +G+                  A   AS ID +L W D+ WL+S+  
Sbjct: 185 SMAAHPRWTAGMLRNGMPKIGNLAPYGMGSNLMEQARNAASQIDPTLTWKDLDWLRSVWP 244

Query: 238 LPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFI 297
             + +KG++ A DA    + GA  + +SNHG RQ+D   +++  L ++ ++++G   V +
Sbjct: 245 GQLAVKGIMDAGDALACQKAGAQTVIVSNHGGRQMDPAPSSLSVLSDIVEALKGETDVIL 304

Query: 298 DSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQ 357
           D GVR G DVV ALALGA AV IGRP  W LA  GE GV  L+  L  E +  ++L G  
Sbjct: 305 DGGVRWGGDVVTALALGAKAVGIGRPWAWALAAGGERGVRSLVDGLGGEIRDVLRLGGMV 364

Query: 358 KVSDIR 363
            ++ +R
Sbjct: 365 DLASLR 370

ref|YP_119507.1| putative L-lactate dehydrogenase [Nocardia farcinica IFM 10152]
dbj|BAD58143.1| putative L-lactate dehydrogenase [Nocardia farcinica IFM 10152]
(416 aa)

Score: 211 bits (537), Expect: 2.95265e-53
Length: 370, Idn/Pos/Gap = 133/195/17 (35%/52%/4%)

Query:   3 EKPAVNPATQPLNLA----EYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFR  58
           +KP +NP  + L+ A    +    AK R P   + Y    A+ E ++    +AF+ + F 
Sbjct:  18 KKPRLNPTRRRLDAALTIEDLRRIAKRRTPRAAFDYTDGAAEAEISIDRARKAFQDIEFH  77

Query:  59 PRVLIDVSRVDITKQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSW 118
           P +L DVS+V    +V+G  +S P  +APT   RM   EGE A AR   R G    LS+ 
Sbjct:  78 PAILRDVSKVTTGWEVLGGPVSLPFGIAPTGFTRMMQTEGEHAGARVAGRAGIPFSLSTM 137

Query: 119 ATTSLEDVAAHVPGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREAD 178
            T S+EDVAA  P    +FQLY++KDR  +  LV RA  AGF  + +TVD P  G R  D
Sbjct: 138 GTASIEDVAAANPHGRNWFQLYMWKDRDRSMALVERAATAGFDTLLVTVDVPVAGARLRD 197

Query: 179 IRNQFQLPPHLSLANFADMK-------DFAQVKGGAGAS------GLASYVASLIDASLN 225
            RN   +PP L+ A   D         DF   +  A AS       +A  + ++ D ++ 
Sbjct: 198 TRNGMSIPPALTPATVLDALPRPRWWIDFLTTEPLAFASLDRWSGTVAELLDTMFDPTVT 257

Query: 226 WNDIAWLKSITRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEV 285
           + D+AW++      +++KG+ T  DA+  +  G DGI +SNHG RQLD        L EV
Sbjct: 258 FEDLAWIRDQWPGKVVVKGIQTLADARAVVDTGVDGIVLSNHGGRQLDRAPVPFHLLPEV 317

Query: 286 AQSVRGRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKD 345
           A+ + G   + +D+G+  G D+V A+ALGA   L+GR  ++GL   GE GV R + +L  
Sbjct: 318 ARELGGDTEILLDTGIMSGADIVAAVALGARCTLVGRAYLYGLMAGGEAGVQRAVDILTG 377

Query: 346 EFKLAMQLCG 355
           + +  M+L G
Sbjct: 378 QLERTMRLLG 387

ref|YP_033123.1| L-lactate dehydrogenase [Bartonella henselae str. Houston-1]
emb|CAF27083.1| L-lactate dehydrogenase [Bartonella henselae str. Houston-1]
(383 aa)

Score: 211 bits (537), Expect: 3.31851e-53
Length: 369, Idn/Pos/Gap = 126/197/24 (34%/53%/6%)

Query:  18 EYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGI  77
           +Y   AK RLP  ++ Y   GA  E+T+R N    + L  R R+L  V  VD++ ++   
Sbjct:   8 DYRKAAKRRLPPFLFHYIDGGAYAEETMRRNYADLQALALRQRILRGVGEVDLSTKLFDQ  67

Query:  78 DLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFF 137
            L  P+++AP  +  M    GE+  ARA    G    LSS +   + +V   V G   +F
Sbjct:  68 TLDLPIILAPVGLTGMYARRGEVQAARAAVAKGIPFTLSSVSVCPIAEVQKAV-GSAFWF 126

Query: 138 QLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRN-------------QFQ 184
           QLYV KDR     ++ R+  +G R +  TVD P  G R  D  +             Q  
Sbjct: 127 QLYVLKDRGFMRDVLERSWASGVRTLVFTVDMPVPGARYRDAHSGMSGSYAGLRRILQAF 186

Query: 185 LPPHLSLA--------NFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSIT 236
           + PH +          +  ++  + Q K          ++ +  D S+ W+D+ W++   
Sbjct: 187 IHPHWAWNVGIMGRPHDLGNVSTYLQKK--IALDDYIGWLGANFDPSIGWHDLQWIRDFW 244

Query: 237 RLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVF 296
           +  ++LKG++  EDA+ A+Q+GADGI +SNHG RQLDGV +T+  L  +A++V+  + + 
Sbjct: 245 KGKMILKGILDPEDAREAIQFGADGIVVSNHGGRQLDGVLSTVRALPAIAEAVKSDLTIL 304

Query: 297 IDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGC 356
           +DSGVR G DVV+ +A GADAV+IGR  V+ LA  GE+GV  L+ L  +E ++AM L G 
Sbjct: 305 VDSGVRSGLDVVRMIAQGADAVMIGRAFVYALAAAGEKGVAHLIDLFANEMRVAMTLTGV 364

Query: 357 QKVSDIRRD 365
           + + +I R+
Sbjct: 365 RAIKEITRE 373

gb|AAB18582.1| lctD [Escherichia coli]
(396 aa)

Score: 211 bits (536), Expect: 3.6375e-53
Length: 372, Idn/Pos/Gap = 129/199/20 (34%/53%/5%)

Query:  17 AEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMG  76
           ++Y   A+  LP  ++ Y   GA  E TLR N E    +  R R+L ++S + +   +  
Sbjct:   7 SDYRAAAQRILPPFLFHYMDGGAYSEYTLRRNVEDLSEVALRQRILKNMSDLSLETTLFN  66

Query:  77 IDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKF 136
             LS P+ +AP  +  M    GE+  A+A    G    LS+ +   +E+VA  +   P +
Sbjct:  67 EKLSMPVALAPVGLCGMYARRGEVQAAKAADAHGIPFTLSTVSVCPIEEVAPXIK-RPMW 125

Query: 137 FQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREAD-----------IRNQFQL 185
           FQLYV +DR      + RA+ AG   +  TVD P  G R  D           +R   Q 
Sbjct: 126 FQLYVLRDRGFMRNALERAKAAGCSTLVFTVDMPTPGARYRDAHSGMSGPNAAMRRYLQA 185

Query: 186 PPHLSLANFADMK----DFAQVKGGAGA-SGLASYVASL---IDASLNWNDIAWLKSITR 237
             H   A    +     D   +    G  +GL  Y+  L    D S++W D+ W++    
Sbjct: 186 VTHPQWAWDVGLNGRPHDLGNISAYLGKPTGLEDYIGWLGNNFDPSISWKDLEWIRDFWD 245

Query: 238 LPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFI 297
            P+++KG++  EDA+ A+++GADGI +SNHG RQLDGV ++   L  +A +V+G I +  
Sbjct: 246 GPMVIKGILDPEDARDAVRFGADGIVVSNHGGRQLDGVLSSARALPAIADAVKGDIAILA 305

Query: 298 DSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQ 357
           DSG+R G DVV+ +ALGAD VL+GR  ++ LA  G+ GV  LL+L++ E K+AM L G +
Sbjct: 306 DSGIRNGLDVVRMIALGADTVLLGRAFLYALATAGQAGVANLLNLIEKEMKVAMTLTGAK 365

Query: 358 KVSDIRRDLVVR 369
            +S+I +D +V+
Sbjct: 366 SISEITQDSLVQ 377

ref|ZP_00157502.2| COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Haemophilus influenzae R2866]
(381 aa)

Score: 211 bits (536), Expect: 3.76095e-53
Length: 371, Idn/Pos/Gap = 128/195/20 (34%/52%/5%)

Query:  17 AEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMG  76
           ++Y   A+ R+P  ++ Y   G+  EQTL  N      +  R RVL D+S +D + ++ G
Sbjct:   7 SDYREAARRRVPPFMFHYADGGSYAEQTLARNVSDLENIALRQRVLKDMSELDTSIELFG  66

Query:  77 IDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKF 136
             LS P ++AP     M    GE+  A+A    G    LS+ +   +E+VA  +   P +
Sbjct:  67 EKLSMPTILAPVGACGMYARRGEVQAAQAADNKGVPFTLSTVSICPIEEVAPAIK-RPMW 125

Query: 137 FQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREAD-----------IRNQFQL 185
           FQLYV KDR   +  + RA+ AG   +  TVD P  G R  D           IR   Q 
Sbjct: 126 FQLYVLKDRGFMKNALERAKAAGCSTLVFTVDMPTPGARYRDMHSGMSGPYKEIRRVLQG 185

Query: 186 PPHLSLANFADMKDFAQVKGGAGAS-----GLASYVASL---IDASLNWNDIAWLKSITR 237
             H   A    +K      G          GL  Y+  L    D S++W D+ W++    
Sbjct: 186 FTHPFWAYDVGIKGKPHTLGNVSTYMGRQIGLDDYIGWLTENFDPSISWKDLEWIREFWE 245

Query: 238 LPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFI 297
            P+++KG++  EDA+ A+++GADGI +SNHG RQLDGV ++   L  +A +V+G I +  
Sbjct: 246 GPMVIKGILDPEDAKDAVRFGADGIVVSNHGGRQLDGVLSSARALPPIADAVKGDIKIIA 305

Query: 298 DSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQ 357
           DSG+R G D+V+ LALGADA ++GR  V+ L   G +GV  +L + K E ++AM L   +
Sbjct: 306 DSGIRNGLDIVRMLALGADATMLGRAFVYALGAAGRQGVENMLDIFKKEMRVAMTLTSNR 365

Query: 358 KVSDIRRDLVV 368
            ++DI+ + +V
Sbjct: 366 TIADIKPEALV 376

ref|NP_709384.1| L-lactate dehydrogenase [Shigella flexneri 2a str. 301]
gb|AAN45091.1| L-lactate dehydrogenase [Shigella flexneri 2a str. 301]
ref|NP_839290.1| L-lactate dehydrogenase [Shigella flexneri 2a str. 2457T]
gb|AAP19101.1| L-lactate dehydrogenase [Shigella flexneri 2a str. 2457T]
gb|AAG58752.1| L-lactate dehydrogenase [Escherichia coli O157:H7 EDL933]
dbj|BAB37906.1| L-lactate dehydrogenase [Escherichia coli O157:H7]
ref|NP_312510.1| L-lactate dehydrogenase [Escherichia coli O157:H7]
pir||D86036 L-lactate dehydrogenase [imported] - Escherichia coli  (strain O157:H7, substrain EDL933)
pir||C91189 L-lactate dehydrogenase [imported] - Escherichia coli  (strain O157:H7, substrain RIMD 0509952)
ref|NP_290188.1| L-lactate dehydrogenase [Escherichia coli O157:H7 EDL933]
(396 aa)

Score: 210 bits (535), Expect: 4.51874e-53
Length: 372, Idn/Pos/Gap = 129/199/20 (34%/53%/5%)

Query:  17 AEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMG  76
           ++Y   A+  LP  ++ Y   GA  E TLR N E    +  R R+L ++S + +   +  
Sbjct:   7 SDYRAAAQRILPPFLFHYMDGGAYSEYTLRRNVEDLSEVALRQRILKNMSDLSLETTLFN  66

Query:  77 IDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKF 136
             LS P+ +AP  +  M    GE+  A+A    G    LS+ +   +E+VA  +   P +
Sbjct:  67 EKLSMPVALAPVGLCGMYARRGEVQAAKAADAHGIPFTLSTVSVCPIEEVAPAIK-RPMW 125

Query: 137 FQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREAD-----------IRNQFQL 185
           FQLYV +DR      + RA+ AG   +  TVD P  G R  D           +R   Q 
Sbjct: 126 FQLYVLRDRGFMRNALERAKAAGCSTLVFTVDMPTPGARYRDAHSGMSGPNAAMRRYLQA 185

Query: 186 PPHLSLANFADMK----DFAQVKGGAGA-SGLASYVASL---IDASLNWNDIAWLKSITR 237
             H   A    +     D   +    G  +GL  Y+  L    D S++W D+ W++    
Sbjct: 186 VTHPQWAWDVGLNGRPHDLGNISAYLGKPTGLEDYIGWLGNNFDPSISWKDLEWIRDFWD 245

Query: 238 LPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFI 297
            P+++KG++  EDA+ A+++GADGI +SNHG RQLDGV ++   L  +A +V+G I +  
Sbjct: 246 GPMVIKGILDPEDARDAVRFGADGIVVSNHGGRQLDGVLSSARALPAIADAVKGDIAILA 305

Query: 298 DSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQ 357
           DSG+R G DVV+ +ALGAD VL+GR  ++ LA  G+ GV  LL+L++ E K+AM L G +
Sbjct: 306 DSGIRNGLDVVRMIALGADTVLLGRAFLYALATAGQAGVANLLNLIEKEMKVAMTLTGAK 365

Query: 358 KVSDIRRDLVVR 369
            +S+I +D +V+
Sbjct: 366 SISEITQDSLVQ 377

ref|NP_758729.1| FMN-dependent dehydrogenase [Pseudomonas resinovorans]
dbj|BAC41707.1| FMN-dependent dehydrogenase [Pseudomonas resinovorans]
(392 aa)

Score: 210 bits (534), Expect: 6.30904e-53
Length: 372, Idn/Pos/Gap = 138/196/22 (37%/52%/5%)

Query:  15 NLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQV  74
           ++AE    A+ RLP   + Y + GA DE TL DN + F       R ++        + V
Sbjct:  15 SVAELADMARRRLPYFAWEYLSGGAQDELTLTDNLDGFSAYGLHARAMVPCHPPATARAV  74

Query:  75 MGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLP 134
           +G  L  PL++ PT    + H + ++  ARA    G    LS+ A TSLE + A VP + 
Sbjct:  75 LGRVLPVPLLIGPTGYNGLLHRDADIHLARAATARGLPFCLSTAANTSLEALVAAVPEVN 134

Query: 135 KFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANF 194
            +FQLY   D  +   L+RRA   G R + LT D   LG RE D RN F  P  L+  N 
Sbjct: 135 LWFQLYAMGDPRVQNDLLRRAAAVGSRTLLLTCDAMVLGNREWDRRN-FAKPRQLAWRNT 193

Query: 195 ADM----KDFAQVKGGAGASGLA-----------------SYVASLIDASLNWNDIAWLK 233
            D+    +   QV   AG  G+                  +++   +D+ L+W+ +A L+
Sbjct: 194 LDVLRHPRWLQQVMWPAGLPGMGNLEPYLPLNERNALGSMAFIGRQMDSLLDWDKLARLR 253

Query: 234 SITRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRI 293
                 +LLKGV+   D +RA+  G DG+ +SNHG RQLDG  +++  L  VA   RGR+
Sbjct: 254 DQWGERLLLKGVLHPADVERAIALGLDGVVVSNHGGRQLDGAPSSLAALAAVAPQARGRL 313

Query: 294 PVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQL 353
            + +D G+RRG+D+VKALALGADAVL+GR  ++G+AV GE G  R L LL  E    + L
Sbjct: 314 SLLLDGGIRRGSDIVKALALGADAVLLGRATLYGVAVAGEAGAGRALDLLTQELVQTLNL 373

Query: 354 CGCQKVSDIRRD 365
            GC  +S + RD
Sbjct: 374 MGCTHLSHLGRD 385

ref|NP_418062.1| L-lactate dehydrogenase [Escherichia coli K12]
gb|AAC76629.1| L-lactate dehydrogenase; L-lactate dehydrogenase, FMN-linked [Escherichia coli K12]
pir||C49904 L-lactate dehydrogenase (EC 1.1.1.27), FMN-dependent - Escherichia coli (strain K-12)
sp|P33232|LLDD_ECOLI L-lactate dehydrogenase (Cytochrome)
gb|AAA03585.1| L-lactate dehydrogenase
(396 aa)

Score: 210 bits (534), Expect: 6.80105e-53
Length: 372, Idn/Pos/Gap = 129/199/20 (34%/53%/5%)

Query:  17 AEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMG  76
           ++Y   A+  LP  ++ Y   GA  E TLR N E    +  R R+L ++S + +   +  
Sbjct:   7 SDYRAAAQRILPPFLFHYMDGGAYSEYTLRRNVEDLSEVALRQRILKNMSDLSLETTLFN  66

Query:  77 IDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKF 136
             LS P+ +AP  +  M    GE+  A+A    G    LS+ +   +E+VA  +   P +
Sbjct:  67 EKLSMPVALAPVGLCGMYARRGEVQAAKAADAHGIPFTLSTVSVCPIEEVAPAIK-RPMW 125

Query: 137 FQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREAD-----------IRNQFQL 185
           FQLYV +DR      + RA+ AG   +  TVD P  G R  D           +R   Q 
Sbjct: 126 FQLYVLRDRGFMRNALERAKAAGCSTLVFTVDMPTPGARYRDAHSGMSGPNAAMRRYLQA 185

Query: 186 PPHLSLANFADMK----DFAQVKGGAGA-SGLASYVASL---IDASLNWNDIAWLKSITR 237
             H   A    +     D   +    G  +GL  Y+  L    D S++W D+ W++    
Sbjct: 186 VTHPQWAWDVGLNGRPHDLGNISAYLGKPTGLEDYIGWLGNNFDPSISWKDLEWIRDFWD 245

Query: 238 LPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFI 297
            P+++KG++  EDA+ A+++GADGI +SNHG RQLDGV ++   L  +A +V+G I +  
Sbjct: 246 GPMVIKGILDPEDARDAVRFGADGIVVSNHGGRQLDGVLSSARALPAIADAVKGDIAILA 305

Query: 298 DSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQ 357
           DSG+R G DVV+ +ALGAD VL+GR  ++ LA  G+ GV  LL+L++ E K+AM L G +
Sbjct: 306 DSGIRNGLDVVRMIALGADTVLLGRAFLYALATAGQAGVANLLNLIEKEMKVAMTLTGAK 365

Query: 358 KVSDIRRDLVVR 369
            +S+I +D +V+
Sbjct: 366 SISEITQDSLVQ 377

ref|ZP_00154725.2| COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Haemophilus influenzae R2846]
(381 aa)

Score: 209 bits (533), Expect: 7.9694e-53
Length: 371, Idn/Pos/Gap = 128/194/20 (34%/52%/5%)

Query:  17 AEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMG  76
           ++Y   A+ R+P  ++ Y   G+  EQTL  N      +  R RVL D+S +D + ++ G
Sbjct:   7 SDYREAARRRVPPFMFHYADGGSYAEQTLARNVSDLENIALRQRVLKDMSELDTSIELFG  66

Query:  77 IDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKF 136
             LS P ++AP     M    GE+  A+A    G    LS+ +   +E+VA  +   P +
Sbjct:  67 EKLSMPTILAPVGACGMYARRGEVQAAQAADNKGVPFTLSTVSICPIEEVAPAIK-RPMW 125

Query: 137 FQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREAD-----------IRNQFQL 185
           FQLYV KDR   +  + RA+ AG   +  TVD P  G R  D           IR   Q 
Sbjct: 126 FQLYVLKDRGFMKNALERAKAAGCSTLVFTVDMPTPGARYRDMHSGMSGPYKEIRRVLQG 185

Query: 186 PPHLSLANFADMKDFAQVKGGAGAS-----GLASYVASL---IDASLNWNDIAWLKSITR 237
             H   A    +K      G          GL  Y+  L    D S++W D+ W++    
Sbjct: 186 FTHPFWAYDVGIKGKPHTLGNVSTYMGRQIGLDDYIGWLTENFDPSISWKDLEWIREFWE 245

Query: 238 LPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFI 297
            P+++KG++  EDA+ A+++GADGI +SNHG RQLDGV ++   L  +A +V+G I +  
Sbjct: 246 GPMVIKGILDPEDAKDAVRFGADGIVVSNHGGRQLDGVLSSARALPPIADAVKGDIKIIA 305

Query: 298 DSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQ 357
           DSG+R G D+V+ LALGADA ++GR  V+ L   G +GV  +L + K E ++AM L   +
Sbjct: 306 DSGIRNGLDIVRMLALGADATMLGRAFVYALGAAGRQGVENMLDIFKKEMRVAMTLTSNR 365

Query: 358 KVSDIRRDLVV 368
            + DI+ + +V
Sbjct: 366 TIVDIKPEALV 376

ref|NP_756289.1| L-lactate dehydrogenase [Escherichia coli CFT073]
gb|AAN82863.1| L-lactate dehydrogenase [Escherichia coli CFT073]
(396 aa)

Score: 209 bits (532), Expect: 1.28225e-52
Length: 372, Idn/Pos/Gap = 128/198/20 (34%/53%/5%)

Query:  17 AEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMG  76
           ++Y   A+  LP  ++ Y   GA  E TLR N E    +  R R+L ++S + +   +  
Sbjct:   7 SDYRAAAQRILPPFLFHYMDGGAYSEYTLRRNVEDLSEVALRQRILKNMSDLSLETTLFN  66

Query:  77 IDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKF 136
             LS P+ + P  +  M    GE+  A+A    G    LS+ +   +E+VA  +   P +
Sbjct:  67 EKLSMPVALGPVGLCGMYARRGEVQAAKAADAHGIPFTLSTVSVCPIEEVAPAIK-RPMW 125

Query: 137 FQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREAD-----------IRNQFQL 185
           FQLYV +DR      + RA+ AG   +  TVD P  G R  D           +R   Q 
Sbjct: 126 FQLYVLRDRGFMRNALERAKAAGCSTLVFTVDMPTPGARYRDAHSGMSGPNAAMRRYLQA 185

Query: 186 PPHLSLANFADMK----DFAQVKGGAGA-SGLASYVASL---IDASLNWNDIAWLKSITR 237
             H   A    +     D   +    G  +GL  Y+  L    D S++W D+ W++    
Sbjct: 186 VTHPQWAWDVGLNGRPHDLGNISAYLGKPTGLEDYIGWLGNNFDPSISWKDLEWIRDFWD 245

Query: 238 LPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFI 297
            P+++KG++  EDA+ A+++GADGI +SNHG RQLDGV ++   L  +A +V+G I +  
Sbjct: 246 GPMVIKGILDPEDARDAVRFGADGIVVSNHGGRQLDGVLSSARALPAIADAVKGDIAILA 305

Query: 298 DSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQ 357
           DSG+R G DVV+ +ALGAD VL+GR  ++ LA  G+ GV  LL+L++ E K+AM L G +
Sbjct: 306 DSGIRNGLDVVRMIALGADTVLLGRAFLYALATAGQAGVANLLNLIEKEMKVAMTLTGAK 365

Query: 358 KVSDIRRDLVVR 369
            +S+I +D +V+
Sbjct: 366 SISEITQDSLVQ 377

gb|AAT51599.1| PA4771 [synthetic construct]
(382 aa)

Score: 208 bits (530), Expect: 1.89795e-52
Length: 374, Idn/Pos/Gap = 133/202/24 (35%/54%/6%)

Query:  18 EYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGI  77
           +Y   A+ +LP  ++ Y   GA  E TLR N E    +  R RVL ++S + +  ++   
Sbjct:   8 DYRAAAQRKLPPFLFHYIDGGAYAEYTLRRNVEDLSAIALRQRVLKNMSELSLETRLFDE  67

Query:  78 DLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFF 137
            L+ P+ +AP  +  M    GE+  ARA A  G    LS+ +   +E+VA  +   P +F
Sbjct:  68 TLAMPVALAPVGLTGMYARRGEVQAARAAAAKGVPFTLSTVSVCPIEEVAPAI-DRPMWF 126

Query: 138 QLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADI-----------RNQFQLP 186
           QLYV KDR      + RAE AG   +  TVD P  G R  D            R   Q  
Sbjct: 127 QLYVLKDRGFMRNALERAEAAGVTTLVFTVDMPVPGARYRDAHSGMSGPYAAPRRILQAM 186

Query: 187 PHLS-------LANFADMKDFAQVKGGAGASGLASYVASL---IDASLNWNDIAWLKSIT 236
            H +       L    D+ + +  +G    +GL  Y+  L    D S++W D+ W++   
Sbjct: 187 THPAWAWDVGLLGKPHDLGNISAYRGNP--TGLEDYIGWLGANFDPSISWKDLEWIREFW 244

Query: 237 RLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVF 296
             P+++KG++  EDA+ A+++GADGI +SNHG RQLDGV ++   L  +A +V+G + + 
Sbjct: 245 DGPMVIKGILDPEDARDAVKFGADGIVVSNHGGRQLDGVLSSARALPAIADAVKGELAIL 304

Query: 297 IDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGC 356
            DSG+R G DVV+ +ALGAD+VL+GR  V+ LA  GE GV  LL L++ E ++AM L G 
Sbjct: 305 ADSGIRTGLDVVRMIALGADSVLLGRAFVYALAAAGEAGVRNLLELIEKEMRVAMVLTGA 364

Query: 357 QKVSDIRRDLVVRD 370
           + + +I  D +VR+
Sbjct: 365 KSIGEISADSLVRE 378

gb|AAP95092.1| L-lactate dehydrogenase [Haemophilus ducreyi 35000HP]
ref|NP_872703.1| L-lactate dehydrogenase [Haemophilus ducreyi 35000HP]
(381 aa)

Score: 208 bits (529), Expect: 2.22399e-52
Length: 370, Idn/Pos/Gap = 129/195/20 (34%/52%/5%)

Query:  18 EYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGI  77
           +Y   A+ R+P  ++ Y   G+  E+TL  N      L  R RVL D+S+++   ++ G 
Sbjct:   8 DYREAARRRVPPFMFHYADGGSFSERTLARNVSDLADLALRQRVLKDMSQLNTEIELFGE  67

Query:  78 DLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFF 137
            L+ P+++AP     M    GE+  A+A    G    LS+ +   +E+V   +   P ++
Sbjct:  68 KLAMPIVLAPVGALGMYARRGEVQAAQAAENKGLPFTLSTVSVCPIEEVTPAIK-RPMWY 126

Query: 138 QLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREAD-----------IRNQFQLP 186
           QLYV KDR   + ++ RA+ AG   +  TVD P  G R  D           IR   Q  
Sbjct: 127 QLYVLKDRGFMKSVLERAKAAGCSTLVFTVDMPTPGARYRDLHSGMSGKYKEIRRVLQAM 186

Query: 187 PHLSLANFADMK----DFAQVKGGAGAS-GLASY---VASLIDASLNWNDIAWLKSITRL 238
            H   A    +         V G  G S GL  Y   +A   D S++W D+ W++     
Sbjct: 187 THPRWAWDVGINGKPHTLGNVSGYTGKSVGLDDYAVWLADNFDPSISWKDLEWIRDFWDG 246

Query: 239 PILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFID 298
           P+++KG++  EDA+ A+++GADGI +SNHG RQLDG  ++   L  +A +V+G I +  D
Sbjct: 247 PMVIKGILDVEDAKDAVRFGADGIVVSNHGGRQLDGALSSAKALPSIADAVKGEIKILAD 306

Query: 299 SGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQK 358
           SG+R G DVV+ +ALGADA LIGR  V+ L+  G  GV  +L + + E  +AM L    +
Sbjct: 307 SGIRNGLDVVRMIALGADATLIGRAFVYALSAAGRAGVENMLDIFRKEMHVAMTLTSNAR 366

Query: 359 VSDIRRDLVV 368
           +SDI RD +V
Sbjct: 367 ISDINRDALV 376

emb|CAB38520.1| putative glycolate oxidase [Streptomyces coelicolor A3(2)]
ref|NP_627441.1| putative glycolate oxidase [Streptomyces coelicolor A3(2)]
pir||T36246 probable glycolate oxidase - Streptomyces coelicolor
(377 aa)

Score: 207 bits (526), Expect: 4.91338e-52
Length: 344, Idn/Pos/Gap = 150/208/8 (43%/60%/2%)

Query:  12 QPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDIT  71
           +PL L ++   A+ +LPA  + + A GA  E+TL  NE  F  +R RPR L  +   D +
Sbjct:   3 EPLTLDDFARLARGQLPAATWDFIAGGAGRERTLAANEAVFGAVRLRPRALPGIEEPDTS  62

Query:  72 KQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVP 131
            +V+G     P+ +AP A   +AHP+GE ATA A   +G  + +S++A  SLE+VA    
Sbjct:  63 VEVLGSRWPAPVGIAPVAYHGLAHPDGEPATAAAAGALGLPLVVSTFAGRSLEEVA-RAA 121

Query: 132 GLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSL 191
             P + QLY ++D   T  L RRA  +G++A+ LTVDTP  GRR  D+RN F +P H++ 
Sbjct: 122 SAPLWLQLYCFRDHETTLGLARRARDSGYQALVLTVDTPFTGRRLRDLRNGFAVPAHITP 181

Query: 192 ANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDA 251
           AN            G+   G  S +A   D  L+W+ +A L + + LP+L KGV+TA DA
Sbjct: 182 ANLT-----GTAAAGSATPGAHSRLA--FDRRLDWSFVARLGAASGLPVLAKGVLTAPDA 234

Query: 252 QRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKAL 311
           + A+  G  GI +SNHG RQLDG  AT++ L EV  +VRGR PV +D GVR G DV+ AL
Sbjct: 235 EAAVAAGVAGIVVSNHGGRQLDGAPATLEALPEVVSAVRGRCPVLLDGGVRTGADVLAAL 294

Query: 312 ALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCG 355
           ALGA AVL+GRP ++ LAV G  GV R+L+LL ++F   M L G
Sbjct: 295 ALGARAVLVGRPALYALAVGGASGVRRMLTLLTEDFADTMVLTG 338

ref|NP_253459.1| L-lactate dehydrogenase [Pseudomonas aeruginosa PAO1]
gb|AAG08157.1| L-lactate dehydrogenase [Pseudomonas aeruginosa PAO1]
pir||G83050 L-lactate dehydrogenase PA4771 [imported] - Pseudomonas aeruginosa (strain PAO1)
(381 aa)

Score: 206 bits (525), Expect: 7.09284e-52
Length: 374, Idn/Pos/Gap = 132/202/24 (35%/54%/6%)

Query:  18 EYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGI  77
           +Y   A+ +LP  ++ Y   GA  E TLR N E    +  R RVL ++S + +  ++   
Sbjct:   8 DYRAAAQRKLPPFLFHYIDGGAYAEYTLRRNVEDLSAIALRQRVLKNMSELSLETRLFDE  67

Query:  78 DLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFF 137
            L+ P+ +AP  +  M    GE+  ARA A  G    LS+ +   +E+VA  +   P +F
Sbjct:  68 TLAMPVALAPVGLTGMYARRGEVQAARAAAAKGVPFTLSTVSVCPIEEVAPAI-DRPMWF 126

Query: 138 QLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADI-----------RNQFQLP 186
           QLYV KDR      + RA+ AG   +  TVD P  G R  D            R   Q  
Sbjct: 127 QLYVLKDRGFMRNALERAKAAGVTTLVFTVDMPVPGARYRDAHSGMSGPYAAPRRILQAM 186

Query: 187 PHLS-------LANFADMKDFAQVKGGAGASGLASYVASL---IDASLNWNDIAWLKSIT 236
            H +       L    D+ + +  +G    +GL  Y+  L    D S++W D+ W++   
Sbjct: 187 THPAWAWDVGLLGKPHDLGNISAYRGNP--TGLEDYIGWLGANFDPSISWKDLEWIREFW 244

Query: 237 RLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVF 296
             P+++KG++  EDA+ A+++GADGI +SNHG RQLDGV ++   L  +A +V+G + + 
Sbjct: 245 DGPMVIKGILDPEDARDAVKFGADGIVVSNHGGRQLDGVLSSARALPAIADAVKGELAIL 304

Query: 297 IDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGC 356
            DSG+R G DVV+ +ALGAD+VL+GR  V+ LA  GE GV  LL L++ E ++AM L G 
Sbjct: 305 ADSGIRTGLDVVRMIALGADSVLLGRAFVYALAAAGEAGVRNLLELIEKEMRVAMVLTGA 364

Query: 357 QKVSDIRRDLVVRD 370
           + + +I  D +VR+
Sbjct: 365 KSIGEISADSLVRE 378

ref|ZP_00380514.1| COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Brevibacterium linens BL2]
(422 aa)

Score: 206 bits (524), Expect: 9.11024e-52
Length: 355, Idn/Pos/Gap = 127/187/17 (35%/52%/4%)

Query:  23 AKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGIDLSFP  82
           AK R PA  + Y    A+ E ++  + +AF+ + F P +L DVS+VD T Q++G   + P
Sbjct:  43 AKRRTPAAAFDYTDGAAEGEISMERSVQAFQDIEFHPSILHDVSQVDTTTQILGGSSAMP 102

Query:  83 LMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFFQLYVY 142
             +APT   R+   EGE A A A    G    LS+  TTS+EDV    P    +FQLYV 
Sbjct: 103 FGIAPTGFTRLMQTEGETAGASASGAAGIPFTLSTLGTTSIEDVKKVNPNGRNWFQLYVM 162

Query: 143 KDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANF-------- 194
           + R I+  LV RA  AG+  +  TVDTP  G R  D RN F +PP LS            
Sbjct: 163 RQREISYGLVERAAAAGYDTLFFTVDTPIAGARLRDSRNGFSIPPQLSPKTVLNAIPRPW 222

Query: 195 -------ADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVT 247
                   +   FA +    G  G    + S +D S+++ D+A ++ +    + +KGV T
Sbjct: 223 WWWDFLTTEKLQFASLSETGGTVG--ELLNSAMDPSIDFEDLATIRKMWPGKLAIKGVQT 280

Query: 248 AEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDV 307
             DA++    G D I +SNHG RQLD      + L  VA+ V   + + +D+G+R G D+
Sbjct: 281 VADARKLADLGVDAIVLSNHGGRQLDRAPVPFELLPSVAKEVGQELEIIVDTGIRNGADI 340

Query: 308 VKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDI 362
           V A+ALGAD  LIGR  ++GL   G EGV R +++L ++ +  M+L     V+++
Sbjct: 341 VAAMALGADFTLIGRAYLYGLMAGGREGVDRTIAILSEQVERTMKLLQVSNVAEL 395

ref|ZP_00141209.1| COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Pseudomonas aeruginosa UCBPP-PA14]
(381 aa)

Score: 206 bits (523), Expect: 1.30421e-51
Length: 374, Idn/Pos/Gap = 132/201/24 (35%/53%/6%)

Query:  18 EYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGI  77
           +Y   A+ +LP  ++ Y   GA  E TLR N E    +  R RVL ++S + +  ++   
Sbjct:   8 DYRAAAQRKLPPFLFHYIDGGAYAEYTLRRNVEDLSAIALRQRVLKNMSELSLETRLFDE  67

Query:  78 DLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFF 137
            L+ P+ +AP  +  M    GE+  ARA A  G    LS+ +   +E+VA  +   P +F
Sbjct:  68 TLAMPVALAPVGLTGMYARRGEVQAARAAAAKGVPFTLSTVSVCPIEEVAPAI-DRPMWF 126

Query: 138 QLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADI-----------RNQFQLP 186
           QLYV KDR      + RA+ AG   +  TVD P  G R  D            R   Q  
Sbjct: 127 QLYVLKDRGFMRNALERAKAAGVTTLVFTVDMPVPGARYRDAHSGMSGPYAAPRRILQAM 186

Query: 187 PHLS-------LANFADMKDFAQVKGGAGASGLASYVASL---IDASLNWNDIAWLKSIT 236
            H +       L    D+ + +  +G    +GL  Y+  L    D S+ W D+ W++   
Sbjct: 187 THPAWAWDVGLLGKPHDLGNISAYRGNP--TGLEDYIGWLGANFDPSIAWKDLEWIREFW 244

Query: 237 RLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVF 296
             P+++KG++  EDA+ A+++GADGI +SNHG RQLDGV ++   L  +A +V+G + + 
Sbjct: 245 DGPMVIKGILDPEDARDAVKFGADGIVVSNHGGRQLDGVLSSARALPAIADAVKGELAIL 304

Query: 297 IDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGC 356
            DSG+R G DVV+ +ALGAD+VL+GR  V+ LA  GE GV  LL L++ E ++AM L G 
Sbjct: 305 ADSGIRTGLDVVRMIALGADSVLLGRAFVYALAAAGEAGVRNLLELIEKEMRVAMVLTGA 364

Query: 357 QKVSDIRRDLVVRD 370
           + + +I  D +VR+
Sbjct: 365 KSIGEISADSLVRE 378

ref|YP_031962.1| L-lactate dehydrogenase [Bartonella quintana str. Toulouse]
emb|CAF25762.1| L-lactate dehydrogenase [Bartonella quintana str. Toulouse]
(383 aa)

Score: 206 bits (523), Expect: 1.38265e-51
Length: 372, Idn/Pos/Gap = 134/196/30 (36%/52%/8%)

Query:  18 EYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGI  77
           +Y   AK RLP  ++ Y   GA  E+T+R N    + L  R R+L  V  VD++ ++   
Sbjct:   8 DYRKAAKRRLPPFLFHYIDGGAYAEETMRRNYADLQALALRQRILRQVGEVDLSIKLFDQ  67

Query:  78 DLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFF 137
            L+ P+++AP  +  M    GE+  ARA    G    LSS +  SL +V A V G   +F
Sbjct:  68 RLNLPIVLAPVGLTGMYARRGEVKAARAAVAKGIPFTLSSVSVCSLAEVHAEV-GSGFWF 126

Query: 138 QLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLP----------- 186
           QLYV KDR     ++ R+  AG R +  TVD P  G R  D  +    P           
Sbjct: 127 QLYVLKDRGFMRDVLERSWLAGVRTLVFTVDMPVPGARYRDAHSGMSGPYAGLRRILQAV 186

Query: 187 --PHLSLA--------NFADMKDFAQVKGGAGASGLASYVASL---IDASLNWNDIAWLK 233
             PH +          +  ++  + Q K       L  YV  L    D S+ W+D+ W++
Sbjct: 187 VHPHWAWNVGIMGRPHDLGNVSTYLQKK-----ITLEDYVGWLGANFDPSIGWSDLQWIR 241

Query: 234 SITRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRI 293
              +  ++LKG++  +DA+ A+Q+GADGI +SNHG RQLDGV +T   L  +A+ V G +
Sbjct: 242 DFWKGKMILKGILDPQDAREAVQFGADGIVVSNHGGRQLDGVLSTARALPAIAEVVTGDL 301

Query: 294 PVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQL 353
            +  DSGVR G DVV+ +A GADAV+IGR  ++ LA  GE+GV  LL L  +E ++AM L
Sbjct: 302 TILADSGVRSGLDVVRMIAQGADAVMIGRAFIYALAAAGEKGVMHLLDLFANEMRVAMTL 361

Query: 354 CGCQKVSDIRRD 365
            G + V +I  +
Sbjct: 362 TGVRAVKEITHE 373

gb|EAA54944.1| hypothetical protein MG05735.4 [Magnaporthe grisea 70-15]
ref|XP_360361.1| hypothetical protein MG05735.4 [Magnaporthe grisea 70-15]
(437 aa)

Score: 205 bits (522), Expect: 1.59336e-51
Length: 393, Idn/Pos/Gap = 140/210/28 (35%/53%/7%)

Query:   1 MVEKPAVNPATQPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPR  60
           ++E  A    T P  L +    A+  +    +GY A GA  E+T+  N  AF   R  PR
Sbjct:  41 LLEGRAPPATTDPRGLEQQ---AREHMSPEGFGYVAGGAGAEETVTANRVAFGNWRLVPR  97

Query:  61 VLIDVSRVDITKQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWAT 120
           +L   +  D+  ++ G     PL++AP  +Q   H + EL TARA A +G    +S+ A+
Sbjct:  98 LLRPTAPRDLGVKLFGTRYDNPLVMAPVGVQEAYHEDRELGTARACAELGVPFCVSTAAS 157

Query: 121 TSLEDVAAHVPGLPK--FFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREAD 178
           +++E++A    G     ++QLY   D  IT  L+ RA RAG R + +T+DT  +  R  D
Sbjct: 158 STVEEIAEASSGSSAGLWYQLYWPLDDEITASLLGRARRAGCRVLLVTLDTHSMSWRPRD 217

Query: 179 IRNQFQLPPHLSLAN---FAD----MKDFAQV-KGGAGASGLASYVASLIDASLNWNDIA 230
           +   F +P  +   N   F+D     K  AQV +GG     LA+   + I ASL W    
Sbjct: 218 LDRGF-IPFAVGSGNAMGFSDPVFRRKFAAQVNEGGEEDEDLATPEGNPIAASLAWTAEV 276

Query: 231 W---------LKSITRL-----PILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVT 276
           +         L  + R+     PI+LKG+++ EDA+ AL+YG DGI +SNHG RQLDG  
Sbjct: 277 FSGYAHRWTELAKLRRMWGEGNPIVLKGILSVEDARLALEYGMDGIVVSNHGGRQLDGAI 336

Query: 277 ATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGV 336
           A +D L E+  +V G + V  DSGVR G DV+ AL LGA  VL+GRP+++GL + G+EG 
Sbjct: 337 AALDVLPEIVDAVGGNMTVLFDSGVRSGADVINALCLGAKGVLVGRPVIYGLGIAGKEGA 396

Query: 337 YRLLSLLKDEFKLAMQLCGCQKVSDIRRDLVVR 369
             +L+ +  +   +M L G   + ++ RD + R
Sbjct: 397 QHVLASILADLDQSMGLAGVNNIGELTRDRLRR 429

ref|NP_961893.1| hypothetical protein MAP2959c [Mycobacterium avium subsp. paratuberculosis str. k10]
gb|AAS05276.1| hypothetical protein MAP2959c [Mycobacterium avium subsp. paratuberculosis str. k10]
(386 aa)

Score: 205 bits (522), Expect: 1.71762e-51
Length: 363, Idn/Pos/Gap = 138/192/7 (38%/52%/1%)

Query:  13 PLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITK  72
           P+  AE    A+  +   V+ Y   GA DE+T R N EAF R    PR+ +  +  D++ 
Sbjct:  23 PMAFAELESRAERAMSPSVWSYVTGGAGDERTQRANREAFDRWGLIPRMFVGAAERDLSV  82

Query:  73 QVMGIDLSFPLMVAPTAMQRMAHPEG--ELATARAVARIGTVMGLSSWATTSLEDVAAHV 130
           Q+ G+ L  P+ +AP  +  +   +G  +LATARA A  G  M +S+     +EDVAA  
Sbjct:  83 QMFGLTLPSPVFMAPIGVIGICAQDGHGDLATARAAAATGVPMVVSTLTADPMEDVAAQF 142

Query: 131 PGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRN-QFQLPPHL 189
              P FFQLY  KDR +   LV RAE AGF+ I +T+DT   G R  D+    F     +
Sbjct: 143 GDTPGFFQLYTPKDRELAASLVHRAEAAGFKGIIVTLDTWIPGWRPRDLSTANFPQLRGM 202

Query: 190 SLANFADMKDFAQVKGGAGASGLASYVASLIDA---SLNWNDIAWLKSITRLPILLKGVV 246
            L+N+     F               V   I      L W+D+ WL+S+T LP+++KG+ 
Sbjct: 203 CLSNYTSDPVFRAALARPPEEDPQGTVLQWISTFGNPLTWDDLPWLRSLTDLPLIIKGIC 262

Query: 247 TAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTD 306
             +DA+RA   G DGI+ S HG RQ +G    +DCL  V ++  G +PV  DSG+R G D
Sbjct: 263 HPDDARRARDGGVDGIYCSTHGGRQANGGLPALDCLPGVIEAADG-LPVLFDSGIRSGAD 321

Query: 307 VVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDL 366
           VVKALALGA AV IGRP  +GLA+ G +G+   L  +  E  L M + G     D+  D 
Sbjct: 322 VVKALALGATAVGIGRPYAYGLALGGVDGIVHALRSILAEADLIMAVDGYPTRKDLTPDT 381

Query: 367 VVR 369
           + R
Sbjct: 382 LRR 384

gb|AAL22553.1| L-lactate dehydrogenase [Salmonella typhimurium LT2]
ref|NP_462594.1| L-lactate dehydrogenase [Salmonella typhimurium LT2]
(396 aa)

Score: 204 bits (520), Expect: 2.92981e-51
Length: 373, Idn/Pos/Gap = 130/199/20 (34%/53%/5%)

Query:  17 AEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMG  76
           ++Y   A+  LP  ++ Y   GA  E TLR N E   ++  R RVL ++S + +   +  
Sbjct:   7 SDYRAAAQRTLPPFLFHYIDGGAYAEYTLRRNVEDLSQVALRQRVLKNMSDLSLETTLFN  66

Query:  77 IDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKF 136
             LS P+ +AP  +  M    GE+  A A    G    LS+ +   +E+VA  +   P +
Sbjct:  67 ETLSMPVALAPVGLCGMYARRGEVQAAAAADAKGIPFTLSTVSVCPIEEVAPTIK-RPMW 125

Query: 137 FQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREAD-----------IRNQFQL 185
           FQLYV +DR      + RA+ AG   +  TVD P  G R  D           +R  +Q 
Sbjct: 126 FQLYVLRDRGFMRNALERAKAAGCSTLVFTVDMPTPGARYRDAHSGMSGPNAAMRRYWQA 185

Query: 186 PPHLSLANFADMK----DFAQVKGGAGA-SGLASYVASL---IDASLNWNDIAWLKSITR 237
             H   A    +     D   +    G  +GL  Y+  L    D S++W D+ W++    
Sbjct: 186 VMHPKWAWDVGLNGRPHDLGNISAYLGKPTGLEDYIGWLANNFDPSISWKDLEWIREFWD 245

Query: 238 LPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFI 297
            P+++KG++  EDA+ A+++GADGI +SNHG RQLDGV ++   L  +A +V+G I +  
Sbjct: 246 GPMVIKGILDPEDARDAVRFGADGIVVSNHGGRQLDGVLSSARALPAIADAVKGDIAILA 305

Query: 298 DSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQ 357
           DSG+R G DVV+ +ALGAD VL+GR  ++ LA  G+ GV  LL L++ E K+AM L G +
Sbjct: 306 DSGIRNGLDVVRMIALGADTVLLGRAYLYALATAGKAGVANLLDLIEKEMKVAMTLTGAK 365

Query: 358 KVSDIRRDLVVRD 370
            +S+I  D +V++
Sbjct: 366 SISEISGDSLVQE 378

ref|NP_435462.1| putative FMN-dependent [Sinorhizobium meliloti 1021]
gb|AAK64874.1| putative FMN-dependent [Sinorhizobium meliloti 1021]
pir||H95288 probable FMN-dependent [imported] - Sinorhizobium meliloti  (strain 1021) magaplasmid pSymA
(381 aa)

Score: 204 bits (520), Expect: 2.95436e-51
Length: 369, Idn/Pos/Gap = 126/194/20 (34%/52%/5%)

Query:  14 LNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQ  73
           +N+ ++   A+ R P + + Y   G+ +E+T+R N   F RL  R  VL++    D+   
Sbjct:   4 VNIDDFRDLARRRRPKIFFDYIDGGSFEEETMRANRSDFSRLTLRQNVLVEPQPQDLATA  63

Query:  74 VMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGL 133
            +G     P M+ P     +   +GE+   RA    G    LS+++  SL D+     G 
Sbjct:  64 YLGKRHPLPFMLGPVGFLGLYSGKGEVKAVRAAHAAGIPFCLSTFSIASLADLRIVTDG- 122

Query: 134 PKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQL-------- 185
           P  FQLYV +DR++ E  +R AE AG   + +TVDT   G RE D+RN F+         
Sbjct: 123 PLHFQLYVLEDRSLCEEFLRAAEYAGVDTLFVTVDTAITGIRERDVRNGFRSLTRVTPDL 182

Query: 186 -------PPHLSLANFADMKDFAQVKG----GAGASGLASYVASLIDASLNWNDIAWLKS 234
                  P  L+    A M     V+     G GA   A+ ++  ID +L+W DIAWL+ 
Sbjct: 183 FARLALKPRWLAEVVLAGMPSVRAVEHRPEFGRGALEQAANLSRRIDKTLSWKDIAWLRE 242

Query: 235 ITRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIP 294
                +++KGV+T  DA RA   G DG+ +SNHG RQLDG  +TI  L  +  +V     
Sbjct: 243 RWAGKLVIKGVLTPADAVRARDLGCDGVVVSNHGGRQLDGAPSTIRALPSIRATVGTDFC 302

Query: 295 VFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLC 354
           + +D G+RRG DV+KA+ALGAD V++GR   +GL+  G+ GV  ++++L+ E  +++ L 
Sbjct: 303 LMLDGGIRRGADVIKAIALGADGVMLGRAYAYGLSAAGQAGVAEVIAILEREISISLALM 362

Query: 355 GCQKVSDIR 363
           G   V  ++
Sbjct: 363 GIASVEQLK 371

ref|NP_302368.1| L-lactate dehydrogenase [Mycobacterium leprae TN]
emb|CAC31001.1| L-lactate dehydrogenase [Mycobacterium leprae]
pir||A87165 L-lactate dehydrogenase [imported] - Mycobacterium leprae
(414 aa)

Score: 204 bits (519), Expect: 3.70085e-51
Length: 357, Idn/Pos/Gap = 127/193/17 (35%/54%/4%)

Query:  14 LNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQ  73
           L + +    AK R P   + Y    A+DE +++  ++AFR + F P +L DV+ V     
Sbjct:  35 LTIQDLRCIAKQRTPKAAFDYTDGAAEDELSIKRAQQAFRDIEFHPAILRDVTNVCAGWD  94

Query:  74 VMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGL 133
           V+G  +  P  +APT   R+ H EGE+A ARA A  G    LS+ AT+++EDV A VP  
Sbjct:  95 VLGHSVLLPFGIAPTGFTRLMHTEGEIAGARAAAAAGIPFSLSTLATSAIEDVVAAVPQG 154

Query: 134 PKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLAN 193
            K+FQLY+++DR  +  LV RA  AG+ A+ +TVD P  G R  D RN   +PP L+L  
Sbjct: 155 RKWFQLYMWRDRDRSMALVERAADAGYDALLVTVDVPVAGARLRDTRNGMSIPPALTLRT 214

Query: 194 FADMKD---------------FAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRL 238
             D                  FA +   +G   ++ Y+ ++ D S+ ++D+AW+K+    
Sbjct: 215 VFDALPHPRWWIDLLTTEPLAFASLDRWSGT--VSDYLNTMFDPSVTFDDLAWIKTQWPG 272

Query: 239 PILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFID 298
             ++KG+ T +DA+  ++ G DG+ +SNHG RQLD        L  VA+       + +D
Sbjct: 273 KFVVKGIQTLDDARAVVERGIDGVVLSNHGGRQLDRAPVPFHLLPTVAREFGKDTEILLD 332

Query: 299 SGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCG 355
           +G+  G D+V A+ALGA   L+GR  ++GL   GE GV R + +L+      MQL G
Sbjct: 333 TGIMSGADIVAAIALGARCTLVGRAYLYGLMAGGEAGVRRAIEILESGVIRTMQLLG 389

ref|YP_152659.1| putative L-lactate dehydrogenase [Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150]
gb|AAV79347.1| putative L-lactate dehydrogenase [Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150]
(396 aa)

Score: 204 bits (519), Expect: 3.95632e-51
Length: 373, Idn/Pos/Gap = 130/199/20 (34%/53%/5%)

Query:  17 AEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMG  76
           ++Y   A+  LP  ++ Y   GA  E TLR N E   ++  R RVL ++S + +   +  
Sbjct:   7 SDYRAAAQRTLPPFLFHYIDGGAYAEYTLRRNVEDLSQVALRQRVLKNMSDLSLETTLFN  66

Query:  77 IDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKF 136
             LS P+ +AP  +  M    GE+  A A    G    LS+ +   +E+VA  +   P +
Sbjct:  67 ETLSMPVALAPVGLCGMYARRGEVQAAAAADAKGIPFTLSTVSVCPIEEVAPTIQ-RPMW 125

Query: 137 FQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREAD-----------IRNQFQL 185
           FQLYV +DR      + RA+ AG   +  TVD P  G R  D           +R  +Q 
Sbjct: 126 FQLYVLRDRGFMRNALERAKAAGCSTLVFTVDMPTPGARYRDAHSGMSGPNAAMRRYWQA 185

Query: 186 PPHLSLANFADMK----DFAQVKGGAGA-SGLASYVASL---IDASLNWNDIAWLKSITR 237
             H   A    +     D   +    G  +GL  Y+  L    D S++W D+ W++    
Sbjct: 186 VMHPKWAWDVGLNGRPHDLGNISAYLGKPTGLEDYIGWLANNFDPSISWKDLEWIREFWD 245

Query: 238 LPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFI 297
            P+++KG++  EDA+ A+++GADGI +SNHG RQLDGV ++   L  +A +V+G I +  
Sbjct: 246 GPMVIKGILDPEDARDAVRFGADGIVVSNHGGRQLDGVLSSARALPAIADAVKGDIAILA 305

Query: 298 DSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQ 357
           DSG+R G DVV+ +ALGAD VL+GR  ++ LA  G+ GV  LL L++ E K+AM L G +
Sbjct: 306 DSGIRNGLDVVRMIALGADTVLLGRAYLYALATAGKAGVANLLDLVEKEMKVAMTLTGAK 365

Query: 358 KVSDIRRDLVVRD 370
            +S+I  D +V++
Sbjct: 366 SISEISGDSLVQE 378

ref|NP_807446.1| putative L-lactate dehydrogenase [Salmonella enterica subsp. enterica serovar Typhi Ty2]
ref|NP_458232.1| putative L-lactate dehydrogenase [Salmonella enterica subsp. enterica serovar Typhi str. CT18]
emb|CAD03300.1| putative L-lactate dehydrogenase [Salmonella enterica subsp. enterica serovar Typhi]
gb|AAO71306.1| putative L-lactate dehydrogenase [Salmonella enterica subsp. enterica serovar Typhi Ty2]
pir||AH0975 L-lactate dehydrogenase (cytochrome) (EC 1.1.2.3) - Salmonella enterica subsp. enterica serovar Typhi (strain CT18)
(396 aa)

Score: 204 bits (519), Expect: 4.02289e-51
Length: 375, Idn/Pos/Gap = 132/200/24 (35%/53%/6%)

Query:  17 AEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMG  76
           ++Y   A+  LP  ++ Y   GA  E TLR N E   ++  R RVL ++S + +   +  
Sbjct:   7 SDYRAAAQRTLPPFLFHYIDGGAYAEYTLRRNVEDLSQVALRQRVLKNMSDLSLETTLFN  66

Query:  77 IDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGL--P 134
             LS P+ +AP  +  M    GE+  A A    G    LS+ +   +E+VA   P L  P
Sbjct:  67 ETLSMPVALAPVGLCGMYARRGEVQAAAAADAKGIPFTLSTVSVCPIEEVA---PTLKRP 123

Query: 135 KFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREAD-----------IRNQF 183
            +FQLYV +DR      + RA+ AG   +  TVD P  G R  D           +R  +
Sbjct: 124 MWFQLYVLRDRGFMRNALERAKAAGCSTLVFTVDMPTPGARYRDAHSGMSGPNAAMRRYW 183

Query: 184 QLPPHLSLANFADMK----DFAQVKGGAGA-SGLASYVASL---IDASLNWNDIAWLKSI 235
           Q   H   A    +     D   +    G  +GL  Y+  L    D S++W D+ W++  
Sbjct: 184 QAVMHPKWAWDVGLNGRPHDLGNISAYLGKPTGLEDYIGWLANNFDPSISWKDLEWIREF 243

Query: 236 TRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPV 295
              P+++KG++  EDA+ A+++GADGI +SNHG RQLDGV ++   L  +A +V+G I +
Sbjct: 244 WDGPMVIKGILDPEDARDAVRFGADGIVVSNHGGRQLDGVLSSARALPAIADAVKGDIAI 303

Query: 296 FIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCG 355
             DSG+R G DVV+ +ALGAD VL+GR  ++ LA  G+ GV  LL L++ E K+AM L G
Sbjct: 304 LADSGIRNGLDVVRMIALGADTVLLGRAYLYALATAGKTGVANLLDLIEKEMKVAMTLTG 363

Query: 356 CQKVSDIRRDLVVRD 370
            + +S+I  D +V++
Sbjct: 364 AKSISEISGDSLVQE 378

ref|NP_960519.1| LldD2 [Mycobacterium avium subsp. paratuberculosis str. k10]
gb|AAS03902.1| LldD2 [Mycobacterium avium subsp. paratuberculosis str. k10]
(420 aa)

Score: 203 bits (517), Expect: 6.05476e-51
Length: 346, Idn/Pos/Gap = 131/191/13 (37%/55%/3%)

Query:  23 AKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGIDLSFP  82
           AK R P   + Y    A+DE +++   +AFR + F P +L DVS V     V+G  ++ P
Sbjct:  44 AKRRTPKAAFDYTDGAAEDELSIQRARQAFRDIEFHPTILRDVSTVTAGWDVLGGPVALP 103

Query:  83 LMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFFQLYVY 142
             +APT   R+ H EGE+A ARA AR G    LS+  T ++ED+AA VP   K+FQLY++
Sbjct: 104 FGIAPTGFTRLMHTEGEIAGARAAARAGIPFSLSTLGTCAIEDLAAAVPQSRKWFQLYMW 163

Query: 143 KDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANFADMK---- 198
           K+R  +  LVRRA  AGF  +  TVD P  G R  D RN   +PP L+L    D      
Sbjct: 164 KNRERSMALVRRAADAGFDTLLATVDVPVSGARLRDNRNGMTIPPTLTLRTVLDAVPHPK 223

Query: 199 ---DFAQVKGGAGAS------GLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAE 249
              D    +  A AS       +A Y++++ D SL ++D+ W+K+     +++KG+ T +
Sbjct: 224 WWFDLLTTEPLAFASLDRWPGTVAEYLSTMFDPSLTFDDLEWIKARWPGKLVVKGIQTLD 283

Query: 250 DAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVK 309
           DA+  +  GADGI +SNHG RQLD        L  VA+ +     + +D+G+  G D+V 
Sbjct: 284 DARAVVDRGADGIVLSNHGGRQLDRAPVPFHLLSTVARELGKHTEILLDTGIMSGADIVA 343

Query: 310 ALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCG 355
           A+ALGA   L+GR  ++GL   GE GV R + +L +     M+L G
Sbjct: 344 AIALGARCTLVGRAYLYGLMAGGEAGVTRAIEILAEGVIRTMRLLG 389

ref|ZP_00125426.1| COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Pseudomonas syringae pv. syringae B728a]
(380 aa)

Score: 203 bits (517), Expect: 6.97748e-51
Length: 372, Idn/Pos/Gap = 127/191/20 (34%/51%/5%)

Query:  17 AEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMG  76
           ++Y   AK +LP  ++ Y   GA  E TLR N      +  R RVL +V  V +  ++ G
Sbjct:   7 SDYRAAAKRKLPRFLFDYIDGGAYAEHTLRANGSDLADISLRQRVLKNVDNVSLETRLFG  66

Query:  77 IDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKF 136
             L+ P++++P  +  M    GE+  ARA A       LS+ +  S+E+VA+       +
Sbjct:  67 ESLAMPIILSPVGLSGMYARRGEVQVARAAANKRIPFCLSTVSVCSIEEVASQ-SDQAIW 125

Query: 137 FQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLP---PH----- 188
           FQLYV KDR   +  + RA+ AG   +  TVD P  G R  D  +    P   P      
Sbjct: 126 FQLYVLKDRGFMKNALERAKAAGVTTLVFTVDMPTPGARYRDAHSGMSGPYAAPRRILQA 185

Query: 189 -------LSLANFADMKDFAQVKGGAG-ASGLASYVASL---IDASLNWNDIAWLKSITR 237
                  L++       D   +    G A+ L  YV  L    D S++W D+ W++   +
Sbjct: 186 MTKPDWALNVGLLGRPHDLGNISRYLGKATTLEDYVGWLANNFDPSISWKDLEWIREFWQ 245

Query: 238 LPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFI 297
            P+++KG++  +DA+ AL +GADGI +SNHG RQLDGV +T   L  + Q+V   + V  
Sbjct: 246 GPMIIKGILDPQDARDALSFGADGIVVSNHGGRQLDGVLSTAKALPPIVQAVGSDLTVLA 305

Query: 298 DSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQ 357
           DSG+R G DVV+ LALGA  VL+GR + + L  DG+ GV  +L +   E  +AM L G  
Sbjct: 306 DSGIRSGLDVVRMLALGAKGVLLGRSMAYALGADGQRGVENMLDIFAREMHVAMTLTGVT 365

Query: 358 KVSDIRRDLVVR 369
            +  I   ++V+
Sbjct: 366 SIEQIDASILVK 377

ref|ZP_00279244.1| COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Burkholderia fungorum LB400]
(405 aa)

Score: 202 bits (515), Expect: 1.12266e-50
Length: 363, Idn/Pos/Gap = 132/195/24 (36%/53%/6%)

Query:  23 AKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVL--IDVSRVDITKQVMGIDLS  80
           A   +P     Y   GA+ E T++ N   F +     +VL  I  +  D+    +G    
Sbjct:   2 ASHNVPKHFLDYLQGGANSETTMQSNRLDFAQWALIQKVLAGIQENSTDLGTTYLGERHE  61

Query:  81 FPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVA-AHVPGLPKFFQL 139
            P+++ P     M H  GE+A  RA  + G    LS+++  SLE+VA +H   L  +FQL
Sbjct:  62 LPVLLGPVGFAGMYHRNGEIAAGRAAGKAGIAQVLSTFSIASLEEVAQSHRCSL--YFQL 119

Query: 140 YVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANFADMKD 199
           YV++ R +TE ++ R  +A    I LTVDTP    RE D RN F+    LS      M  
Sbjct: 120 YVFRKRELTEHMLERCRKAKIGTIFLTVDTPFAPVRERDARNGFRARTTLSPGMLLSMLR 179

Query: 200 FAQVKGGAGASGLASY-------------------VASLIDASLNWNDIAWLKSITRLPI 240
                 GA A+G+ S                    +  +ID +L W+DI WL+      I
Sbjct: 180 HPLWCMGAIANGIPSVGNCKPYPELGSSLMEQSVNLGRMIDPTLAWSDIKWLRDRWEGKI 239

Query: 241 LLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSG 300
           ++KG++ A+DA+RA+  GA+GI +SNHG RQLD   +TI  L E+A++V  R  V +D G
Sbjct: 240 VIKGILDADDARRAVDAGANGIVVSNHGGRQLDPAPSTISVLPEIAKAVGKRTEVLMDGG 299

Query: 301 VRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVS 360
           +RRG DV+KALALGA AVL+GR  ++GL   GE+GV R L LL++E + A+ + G + + 
Sbjct: 300 IRRGADVLKALALGATAVLLGRAYIYGLGAGGEKGVTRCLDLLREEMRPALNMMGFRTID 359

Query: 361 DIR 363
            ++
Sbjct: 360 QLK 362

ref|NP_216388.1| POSSIBLE L-LACTATE DEHYDROGENASE (CYTOCHROME) LLDD2 [Mycobacterium tuberculosis H37Rv]
emb|CAB06144.1| POSSIBLE L-LACTATE DEHYDROGENASE (CYTOCHROME) LLDD2 [Mycobacterium tuberculosis H37Rv]
gb|AAK46192.1| L-lactate dehydrogenase [Mycobacterium tuberculosis CDC1551]
ref|NP_336378.1| L-lactate dehydrogenase [Mycobacterium tuberculosis CDC1551]
pir||H70667 probable oxidoreductase - Mycobacterium tuberculosis (strain H37RV)
(414 aa)

Score: 202 bits (513), Expect: 1.67564e-50
Length: 357, Idn/Pos/Gap = 129/187/17 (36%/52%/4%)

Query:  14 LNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQ  73
           L + +    AK R P   + Y   GA+DE ++    + FR + F P +L DV+ V     
Sbjct:  35 LTIQDLRRIAKRRTPRAAFDYADGGAEDELSIARARQGFRDIEFHPTILRDVTTVCAGWN  94

Query:  74 VMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGL 133
           V+G     P  +APT   R+ H EGE+A ARA A  G    LS+ AT ++ED+   VP  
Sbjct:  95 VLGQPTVLPFGIAPTGFTRLMHTEGEIAGARAAAAAGIPFSLSTLATCAIEDLVIAVPQG 154

Query: 134 PKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLAN 193
            K+FQLY+++DR  +  LVRR   AGF  + +TVD P  G R  D+RN   +PP L+L  
Sbjct: 155 RKWFQLYMWRDRDRSMALVRRVAAAGFDTMLVTVDVPVAGARLRDVRNGMSIPPALTLRT 214

Query: 194 FADMKD---------------FAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRL 238
             D                  FA +    G  G   Y+ ++ D SL ++D+AW+KS    
Sbjct: 215 VLDAMGHPRWWFDLLTTEPLAFASLDRWPGTVG--EYLNTVFDPSLTFDDLAWIKSQWPG 272

Query: 239 PILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFID 298
            +++KG+ T +DA+  +  G DGI +SNHG RQLD        L  VA+ +     + +D
Sbjct: 273 KLVVKGIQTLDDARAVVDRGVDGIVLSNHGGRQLDRAPVPFHLLPHVARELGKHTEILVD 332

Query: 299 SGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCG 355
           +G+  G D+V A+ALGA   LIGR  ++GL   GE GV R + +L+      M+L G
Sbjct: 333 TGIMSGADIVAAIALGARCTLIGRAYLYGLMAGGEAGVNRAIEILQTGVIRTMRLLG 389

ref|YP_218605.1| L-lactate dehydrogenase [Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67]
gb|AAX67524.1| L-lactate dehydrogenase [Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67]
(396 aa)

Score: 202 bits (513), Expect: 1.71812e-50
Length: 373, Idn/Pos/Gap = 127/196/20 (34%/52%/5%)

Query:  17 AEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMG  76
           ++Y   A+  LP  ++ Y   GA  E TLR N E   ++  R RVL ++S + +   +  
Sbjct:   7 SDYRAAAQRTLPPFLFHYIDGGAYAEYTLRRNVEDLSQVALRQRVLKNMSDLSLETTLFN  66

Query:  77 IDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKF 136
             L  P+ +AP  +  M    GE+  A A    G    LS+ +   +E+VA  +   P +
Sbjct:  67 ETLPMPVALAPVGLCGMYARRGEVQAAAAADAKGIPFTLSTVSVCPIEEVAPTIQ-RPMW 125

Query: 137 FQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANFAD 196
           FQLYV +DR      + RA+ AG   +  TVD P  G R  D  +    P    L  +  
Sbjct: 126 FQLYVLRDRGFMRNALERAKAAGCSTLVFTVDMPTPGARYRDAHSGMSGPNAAMLRYWQA 185

Query: 197 M---------------KDFAQVKGGAGA-SGLASYVASL---IDASLNWNDIAWLKSITR 237
           +                D   +    G  +GL  Y+  L    D S++W D+ W++    
Sbjct: 186 VMHPKWAWDVGLNGRPHDLGNISAYLGKPTGLEDYIGWLANNFDPSISWKDLEWIREFWD 245

Query: 238 LPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFI 297
            P+++KG++  EDA+ A+++GADGI +SNHG RQLDGV ++   L  +A +V+G I +  
Sbjct: 246 GPMVIKGILDPEDARDAVRFGADGIVVSNHGGRQLDGVLSSARALPAIADAVKGDIAILA 305

Query: 298 DSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQ 357
           DSG+R G DVV+ +ALGAD VL+GR  ++ LA  G+ GV  LL L++ E K+AM L G +
Sbjct: 306 DSGIRNGLDVVRMIALGADTVLLGRAYLYALATAGKAGVANLLDLIEKEMKVAMTLTGAK 365

Query: 358 KVSDIRRDLVVRD 370
            +S+I  D +V++
Sbjct: 366 TISEISGDSLVQE 378

ref|NP_855555.1| POSSIBLE L-LACTATE DEHYDROGENASE (CYTOCHROME) LLDD2 [Mycobacterium bovis AF2122/97]
emb|CAD94606.1| POSSIBLE L-LACTATE DEHYDROGENASE (CYTOCHROME) LLDD2 [Mycobacterium bovis AF2122/97]
(414 aa)

Score: 201 bits (512), Expect: 2.60756e-50
Length: 357, Idn/Pos/Gap = 129/187/17 (36%/52%/4%)

Query:  14 LNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQ  73
           L + +    AK R P   + Y    A+DE ++    + FR + F P +L DV+ V     
Sbjct:  35 LTIQDLRRIAKRRTPRAAFDYADGAAEDELSIARARQGFRDIEFHPTILRDVTTVCAGWN  94

Query:  74 VMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGL 133
           V+G     P  +APT   R+ H EGE+A ARA A  G    LS+ AT ++ED+   VP  
Sbjct:  95 VLGQPTVLPFGIAPTGFTRLMHTEGEIAGARAAAAAGIPFSLSTLATCAIEDLVIAVPQG 154

Query: 134 PKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLAN 193
            K+FQLY+++DR  +  LVRRA  AGF  + +TVD P  G R  D+RN   +PP L+L  
Sbjct: 155 RKWFQLYMWRDRDRSMALVRRAAAAGFDTMLVTVDVPVAGARLRDVRNGMSIPPALTLRT 214

Query: 194 FADMKD---------------FAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRL 238
             D                  FA +    G  G   Y+ ++ D SL ++D+AW+KS    
Sbjct: 215 VLDAMGHPRWWFDLLTTEPLAFASLDRWPGTVG--EYLNTVFDPSLTFDDLAWIKSQWPG 272

Query: 239 PILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFID 298
            +++KG+ T +DA+  +  G DGI +SNHG RQLD        L  VA+ +     + +D
Sbjct: 273 KLVVKGIQTLDDARAVVDRGVDGIVLSNHGGRQLDRAPVPFHLLPHVARELGKHTEILVD 332

Query: 299 SGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCG 355
           +G+  G D+V A+ALGA   LIGR  ++GL   GE GV R + +L+      M+L G
Sbjct: 333 TGIMSGADIVAAIALGARCTLIGRAYLYGLMAGGEAGVNRAIEILQTGVIRTMRLLG 389

gb|EAA62327.1| hypothetical protein AN5146.2 [Aspergillus nidulans FGSC A4]
ref|XP_409283.1| hypothetical protein AN5146.2 [Aspergillus nidulans FGSC A4]
(475 aa)

Score: 200 bits (508), Expect: 6.75041e-50
Length: 362, Idn/Pos/Gap = 131/186/26 (36%/51%/7%)

Query:   9 PATQPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRV  68
           P    LN+ +    A  ++    + YY S +DD+ T + N + +R +  RPRV ID S+ 
Sbjct: 100 PMEALLNMDDIEQLATKKVSKKAWAYYYSASDDKITKQFNTDVYRAITLRPRVFIDCSKC 159

Query:  69 DITKQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAA 128
           D+    +G  L  P+ V+P AM R+ +P GE   A A    G +  +S+ A+ + E +  
Sbjct: 160 DLDISCLGYKLGIPIYVSPAAMARLGNPAGEAGIAEACRSFGAMQIISNNASMTPEQIVE 219

Query: 129 HVPGLPKF-FQLYVYKDRAITE-RLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLP 186
           +      F +QLYV  +R  +E +L R  +    + + LT+D P  G+RE D R      
Sbjct: 220 NAAPDQVFGWQLYVQTNRKKSEAQLARVNKLKAIKFVVLTLDAPVPGKREDDERGN---- 275

Query: 187 PHLSLANFADMKDFAQVKGGAGASGLASYVASLIDASLNWND-IAWLKSITRLPILLKGV 245
                         A    G G SG+   +    D +L W D + WLK  T LPI+LKG+
Sbjct: 276 --------------AATGAGQGESGVGKQLFQGTDPTLTWRDTLPWLKKHTDLPIILKGL 321

Query: 246 VTAEDAQRALQYG--ADGIWISNHGARQLDGVTATIDCLEEVAQ---SVRGRIPVFIDSG 300
            T EDA  A  +G    GI +SNHG R LD     +  L E+ +    V  ++ V +D G
Sbjct: 322 QTHEDAYIASLHGPQVKGIILSNHGGRALDTAPPAVHTLLEIRKYCPEVFDKLEVLVDGG 381

Query: 301 VRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVS 360
           +RRGTDVVKAL LGA AV IGRP +WGL   G  GV R L +L DE   AM+L GC++V 
Sbjct: 382 IRRGTDVVKALCLGAKAVGIGRPALWGLGAGGVAGVKRTLQILADETSTAMRLLGCERVE 441

Query: 361 DI 362
            +
Sbjct: 442 QL 443

gb|EAA71109.1| hypothetical protein FG03439.1 [Gibberella zeae PH-1]
ref|XP_383615.1| hypothetical protein FG03439.1 [Gibberella zeae PH-1]
(452 aa)

Score: 199 bits (506), Expect: 1.23093e-49
Length: 379, Idn/Pos/Gap = 134/196/45 (35%/51%/11%)

Query:   9 PATQPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRV  68
           P     N A++   A  ++PA  +GY    A    T + N +AF R R RPR L+DV+R 
Sbjct:  36 PPLFSTNPAQWESLASEKVPAANFGYVYGSASSAATAKANTDAFNRYRLRPRFLVDVTRR  95

Query:  69 DITKQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAA 128
           D+  ++ G +   PL+V+P  +Q + HP+ E ATARA   +G  M LS+ AT S+E VA 
Sbjct:  96 DVGVELFGTEYRSPLLVSPIGVQSILHPDAEEATARACHNVGVPMILSTAATRSIEQVAN 155

Query: 129 HVPGLPKFFQLYVYKDR--AITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLP 186
                 ++FQLY  K +   +T  L+ RA+ +G++ + +T+DT  LG R  D+   + LP
Sbjct: 156 ANADGDRWFQLYWPKPQYEEVTASLLARAKASGYKVLVVTLDTFSLGWRPTDLDTSY-LP 214

Query: 187 ---PHLSLANFAD----------------------------MKDFAQVKGGAGASGLASY 215
                     F+D                            M+    V G A     A  
Sbjct: 215 FVWGQGCQVGFSDPVFNQLFDEMQKNDSRGVGEKLAELWSIMRRPGTVYGAARVLANART 274

Query: 216 VAS------LIDASL--NWNDIAWLKSITRLPILLKGVVTAEDAQRALQYGADGIWISNH 267
           +A       +I++     W  +  LK +   PI+LKG+ T EDA  A+++G DGI +SNH
Sbjct: 275 MAKSKAWIDVINSGTYREWAHLKILKELWDGPIVLKGIQTVEDAHLAIEHGMDGIIVSNH 334

Query: 268 GARQLDGVTATIDCLEEVAQSVR---GRIPVFIDSGVRRGTDVVKALALGADAVLIGRPI 324
           G RQLDG  A++D L E+A   +     + +  DSGVR G+D++KALALGA AV IGRP 
Sbjct: 335 GGRQLDGAVASLDALAEIAADEKVKSSNLTIIFDSGVRTGSDILKALALGAKAVSIGRPY 394

Query: 325 VWGLAVDGEEGVYRLLSLL 343
            +GLA  G++GV  +L  L
Sbjct: 395 AYGLAAGGQQGVEHVLKCL 413

dbj|BAC00312.1| L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Corynebacterium glutamicum ATCC 13032]
(405 aa)

Score: 199 bits (505), Expect: 1.60764e-49
Length: 379, Idn/Pos/Gap = 132/194/21 (34%/51%/5%)

Query:   3 EKPAVNPATQPLN--LAEYHL--FAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFR  58
           +KP +N   + L+  L  Y L   AK R PA  + Y    A+ E ++    EAF  + F 
Sbjct:   4 KKPELNGKKRRLDSALTIYDLRKIAKRRTPAAAFDYTDGAAEAELSITRAREAFENIEFH  63

Query:  59 PRVLIDVSRVDITKQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSW 118
           P +L     VD T Q++G   S P  +APT   R+   EGE+A A A    G    LS+ 
Sbjct:  64 PDILKPAEHVDTTTQILGGTSSMPFGIAPTGFTRLMQTEGEIAGAGAAGAAGIPFTLSTL 123

Query: 119 ATTSLEDVAAHVPGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREAD 178
            TTS+EDV A  P    +FQLYV +DR I+  LV RA +AGF  +  TVDTP  G R  D
Sbjct: 124 GTTSIEDVKATNPNGRNWFQLYVMRDREISYGLVERAAKAGFDTLMFTVDTPIAGYRIRD 183

Query: 179 IRNQFQLPPHLSLANFAD---------------MKDFAQVKGGAGASGLASYVASLIDAS 223
            RN F +PP L+ +   +                 +FA +    G  G    + S +D +
Sbjct: 184 SRNGFSIPPQLTPSTVLNAIPRPWWWIDFLTTPTLEFASLSSTGGTVG--DLLNSAMDPT 241

Query: 224 LNWNDIAWLKSITRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLE 283
           +++ D+  ++ +    +++KGV   ED+ + L  G DG+ +SNHG RQLD        L 
Sbjct: 242 ISYEDLKVIREMWPGKLVVKGVQNVEDSVKLLDQGVDGLILSNHGGRQLDRAPVPFHLLP 301

Query: 284 EVAQSVRGRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLL 343
           +V + V     + ID+G+  G D+V A+A+GAD  LIGR  ++GL   G EGV R +++L
Sbjct: 302 QVRKEVGSEPTIMIDTGIMNGADIVAAVAMGADFTLIGRAYLYGLMAGGREGVDRTIAIL 361

Query: 344 KDEFKLAMQLCGCQKVSDI 362
           + E    M L G   + ++
Sbjct: 362 RSEITRTMALLGVSSLEEL 380

ref|ZP_00165986.1| COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Ralstonia eutropha JMP134]
(363 aa)

Score: 199 bits (505), Expect: 1.69017e-49
Length: 366, Idn/Pos/Gap = 133/196/28 (36%/53%/7%)

Query:  27 LPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGIDLSFPLMVA  86
           LP  ++GY A  A+DE++L  N  AF  +RFRPRVL+DVS      ++ G   + P  +A
Sbjct:   2 LPRPIFGYIAGAAEDEKSLAANRSAFDAVRFRPRVLVDVSGRSQATEIFGQRYASPFGIA  61

Query:  87 PTAMQRMAHPEGELATARAV--ARIGTVMGLSSWATTSLEDVAAHVPGLPKFFQLYVYKD 144
           P  +  +A   G++  A+A   A+I  +M  S  +   +E+V A  PG   +FQ Y+  D
Sbjct:  62 PVGISAIAAYRGDVVLAQAARDAQIPAIM--SGTSLIPMEEVHAAAPG--TWFQAYLPGD 117

Query: 145 RAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLP--PHLSLANFADMK---- 198
               + L+ R   AGF  + LTVD P    RE ++R  F LP  P + LA     +    
Sbjct: 118 ALRRDALIERICAAGFGTLVLTVDIPVWANRENNVRTGFSLPLRPSVRLAFDGVSRPRWL 177

Query: 199 --DFAQVKGGAG----ASGLASYVASLIDAS----------LNWNDIAWLKSITRLPILL 242
              FA+    +G     +  A+  A ++ AS          LNW DI  ++      +++
Sbjct: 178 AGTFARTLLTSGMPHFENSFATRGAPILSASAIRDTTGRDHLNWIDIERIRQRWPGNLVI 237

Query: 243 KGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVR 302
           KG++   DA+RA+  GADGI +SNHG RQLDG    +  L E+  SV     V +DSG+R
Sbjct: 238 KGILHKADAERAVALGADGIIVSNHGGRQLDGAVEPLAVLPEICDSVGHNTAVMMDSGIR 297

Query: 303 RGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDI 362
           RG DV+KALALGA  V +GRP ++  +V G EGV   ++LL+DE    M + G   V+D+
Sbjct: 298 RGGDVLKALALGARFVFLGRPFIYAASVGGPEGVCHAITLLRDEVDRNMAMLGANTVADV 357

Query: 363 RRDLVV 368
            R ++V
Sbjct: 358 NRSVIV 363

ref|YP_227156.1| PUTATIVE L-LACTATE DEHYDROGENASE [Corynebacterium glutamicum ATCC 13032]
emb|CAF20940.1| PUTATIVE L-LACTATE DEHYDROGENASE [Corynebacterium glutamicum ATCC 13032]
ref|NP_602107.1| L-lactate dehydrogenase [Corynebacterium glutamicum ATCC 13032]
(420 aa)

Score: 198 bits (503), Expect: 2.65221e-49
Length: 379, Idn/Pos/Gap = 132/194/21 (34%/51%/5%)

Query:   3 EKPAVNPATQPLN--LAEYHL--FAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFR  58
           +KP +N   + L+  L  Y L   AK R PA  + Y    A+ E ++    EAF  + F 
Sbjct:  19 KKPELNGKKRRLDSALTIYDLRKIAKRRTPAAAFDYTDGAAEAELSITRAREAFENIEFH  78

Query:  59 PRVLIDVSRVDITKQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSW 118
           P +L     VD T Q++G   S P  +APT   R+   EGE+A A A    G    LS+ 
Sbjct:  79 PDILKPAEHVDTTTQILGGTSSMPFGIAPTGFTRLMQTEGEIAGAGAAGAAGIPFTLSTL 138

Query: 119 ATTSLEDVAAHVPGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREAD 178
            TTS+EDV A  P    +FQLYV +DR I+  LV RA +AGF  +  TVDTP  G R  D
Sbjct: 139 GTTSIEDVKATNPNGRNWFQLYVMRDREISYGLVERAAKAGFDTLMFTVDTPIAGYRIRD 198

Query: 179 IRNQFQLPPHLSLANFAD---------------MKDFAQVKGGAGASGLASYVASLIDAS 223
            RN F +PP L+ +   +                 +FA +    G  G    + S +D +
Sbjct: 199 SRNGFSIPPQLTPSTVLNAIPRPWWWIDFLTTPTLEFASLSSTGGTVG--DLLNSAMDPT 256

Query: 224 LNWNDIAWLKSITRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLE 283
           +++ D+  ++ +    +++KGV   ED+ + L  G DG+ +SNHG RQLD        L 
Sbjct: 257 ISYEDLKVIREMWPGKLVVKGVQNVEDSVKLLDQGVDGLILSNHGGRQLDRAPVPFHLLP 316

Query: 284 EVAQSVRGRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLL 343
           +V + V     + ID+G+  G D+V A+A+GAD  LIGR  ++GL   G EGV R +++L
Sbjct: 317 QVRKEVGSEPTIMIDTGIMNGADIVAAVAMGADFTLIGRAYLYGLMAGGREGVDRTIAIL 376

Query: 344 KDEFKLAMQLCGCQKVSDI 362
           + E    M L G   + ++
Sbjct: 377 RSEITRTMALLGVSSLEEL 395

dbj|BAC75193.1| putative L-lactate 2-monooxygenase [Streptomyces avermitilis MA-4680]
ref|NP_828658.1| putative L-lactate 2-monooxygenase [Streptomyces avermitilis MA-4680]
(389 aa)

Score: 198 bits (503), Expect: 2.71944e-49
Length: 349, Idn/Pos/Gap = 132/187/7 (37%/53%/2%)

Query:  13 PLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITK  72
           P +L       + RL     GY A GA +  T R N  A  R R  PR+L DV   D++ 
Sbjct:  25 PTDLTRLEELTEQRLGPGPVGYVAGGAGNGSTARANRSALDRRRIVPRMLRDVHERDLSV  84

Query:  73 QVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPG 132
           +V+G  L  PL +AP  +  + HP+ E A ARA A  G    LSS ++T +E VA  +  
Sbjct:  85 EVLGRTLPAPLALAPVGVLSIMHPDAESAAARAAAAQGVPYILSSASSTPMERVAEAMGD 144

Query: 133 LPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLA 192
             ++FQLY  KDR +T   + RA+ AG+ A+ +T+DTP L  R  D+ +Q  LP    + 
Sbjct: 145 AERWFQLYWAKDREVTRSFLNRAKAAGYTALFVTLDTPLLAWRPRDL-DQAYLPFLHGVG 203

Query: 193 NFADMKDFAQVKGGAGA------SGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVV 246
                 D A   G A        + +  +V+   D    W D+ +L+     PI+LKG++
Sbjct: 204 TANYFTDPAFRAGLAKPVHEDPNAAVMHFVSMFADPGKTWPDLEFLRENWDGPIVLKGIL 263

Query: 247 TAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTD 306
             +DA+RA   G DG+ +SNHG RQ+ G  A  D L  V ++   R+ V  DSG+R G D
Sbjct: 264 HPDDARRAASAGMDGVVVSNHGGRQVAGSVAAADALPRVVEAAGDRLTVLFDSGIRTGDD 323

Query: 307 VVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCG 355
           + KALALGA AVL+GRP  +GL +DG+ GV  ++  L  EF L + L G
Sbjct: 324 IFKALALGARAVLVGRPYAYGLGLDGQAGVEHVVRCLLAEFDLTLALSG 372

gb|AAM10128.1| glycolate oxidase [Arabidopsis thaliana]
gb|AAL38298.1| glycolate oxidase [Arabidopsis thaliana]
(177 aa)

Score: 198 bits (503), Expect: 2.85904e-49
Length: 168, Idn/Pos/Gap = 98/128/0 (58%/76%/0%)

Query: 207 AGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQRALQYGADGIWISN 266
           A  SGLASYVA  ID +L+W D+ WL++IT+LPIL+KGV+T EDA+ A+Q GA GI +SN
Sbjct:   4 ANDSGLASYVAGQIDRTLSWKDVQWLQTITKLPILVKGVLTGEDARIAIQAGAAGIIVSN  63

Query: 267 HGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVW 326
           HGARQLD V ATI  LEEV ++ +GRIPVF+D GVRRGTDV KALALGA  + IGRP+V+
Sbjct:  64 HGARQLDYVPATISALEEVVKATQGRIPVFLDGGVRRGTDVFKALALGASGIFIGRPVVF 123

Query: 327 GLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLVVRDAFAP 374
            LA +GE GV ++L +L+DEF+L M L GC+ + +I R+ +  +   P
Sbjct: 124 SLAAEGEAGVRKVLQMLRDEFELTMALSGCRSLKEISRNHITTEWDTP 171

gb|EAA60338.1| hypothetical protein AN4421.2 [Aspergillus nidulans FGSC A4]
ref|XP_408558.1| hypothetical protein AN4421.2 [Aspergillus nidulans FGSC A4]
(458 aa)

Score: 197 bits (502), Expect: 3.0564e-49
Length: 373, Idn/Pos/Gap = 132/194/20 (35%/52%/5%)

Query:  11 TQPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDI  70
           T P  L +    AK  L    + Y +S A    T   N +AF R R  P  L+D +  D 
Sbjct:  75 TDPTKLEQQ---AKETLSKGGWFYASSNAGLSTTHLANRQAFYRHRIIPNQLVDTNLRDT 131

Query:  71 TKQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVA-AH 129
           T  + G  +S P+  AP  + ++ HP  ELA A+    +     LS+  +T +E V  A+
Sbjct: 132 TTTIFGHTVSAPIGFAPIGINKIYHPSAELAVAKVAGELNLPYCLSTAGSTPIEKVGEAN 191

Query: 130 VPGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHL 189
            PG P+F+QLY+  D  +T  L++RA  +GF A+ LT DT QLG R  D+ N      + 
Sbjct: 192 GPGNPRFYQLYMPHDDELTVSLLKRAWDSGFDAVMLTTDTWQLGWRHDDVANS-NYAFYR 250

Query: 190 SLANFADMKD--FAQVKGGAGASGLASYVAS---LIDA-----SLNWNDIAWL----KSI 235
            L     + D  F +    AG       VA+    ID+     +  W  I WL    K I
Sbjct: 251 GLGADLGLTDPVFQKRCREAGIDPEKDVVAASTKWIDSVWHGRAWTWEKIPWLIKTWKEI 310

Query: 236 T-RLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIP 294
           +   P  +KG+ +  DA++ ++ G DGI +SNH  RQ+DG  A++D LE +A +V  +I 
Sbjct: 311 SGGRPFAIKGIQSVPDAKKCVELGVDGIVVSNHAGRQVDGAIASLDALENIANAVGDQIY 370

Query: 295 VFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLC 354
           +  DSGVR  +DV KALALGA  V +GR  +WGL++ GEEGV  ++  L  +F + M + 
Sbjct: 371 IMYDSGVRGASDVGKALALGAKFVFVGRLWIWGLSIMGEEGVRHVMKSLLADFDILMAVG 430

Query: 355 GCQKVSDIRRDLV 367
           G + V D  R ++
Sbjct: 431 GFKSVKDFDRSIL 443

gb|EAA48677.1| hypothetical protein MG00335.4 [Magnaporthe grisea 70-15]
ref|XP_368909.1| hypothetical protein MG00335.4 [Magnaporthe grisea 70-15]
(510 aa)

Score: 197 bits (501), Expect: 4.05895e-49
Length: 376, Idn/Pos/Gap = 131/194/25 (34%/51%/6%)

Query:   3 EKPAVNPATQPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVL  62
           +K A  P     NL E    AK ++    + YY S  DD+ +   N   +R +  RPRV 
Sbjct: 113 KKQAPPPLETLFNLDEIEEVAKQQVSRKCWAYYWSAGDDQISKVLNGRVYRDILLRPRVF 172

Query:  63 IDVSRVDITKQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTS 122
           +D +  D++  ++G  +  PL V+P AM R+AHP+GE   A+ ++  G +  +S+ A+ +
Sbjct: 173 VDCTSCDLSTTMLGNKVGTPLYVSPAAMARLAHPDGEHGIAKGISSFGGLQIVSNNASQT 232

Query: 123 LED-VAAHVPGLPKFFQLYVYKDRAITERLVRR--AERAGFRAIALTVDTPQLGRREADI 179
            E  V    PG    +QLYV  DR     +++R  A R  ++ I LT+D P  G+RE D 
Sbjct: 233 PEQIVEGAAPGQVFGWQLYVQNDRNKNYAMLKRIHALRDHYKFIVLTLDAPVPGKRELDE 292

Query: 180 RNQFQLPPHLSLANFADMKDFAQVKGGA----GASGLASYVASLIDASLNW-NDIAWLKS 234
           + QF L   ++++        A   GGA       G+   +     A L W   + WL  
Sbjct: 293 KQQF-LESGMTMS--------AASAGGAPKHPAGGGVGQQLFWGTAADLTWTTTLPWLAE 343

Query: 235 ITRLPILLKGVVTAEDAQRALQYGA-----DGIWISNHGARQLDGVTATIDCLEEVAQ-- 287
            T LPI+LKG+ T EDA  A QY A       I +SNHG R LD     +  L E+ +  
Sbjct: 344 HTDLPIVLKGIQTHEDAYLAAQYAAKYGTVKAIILSNHGGRALDTAPPAVHTLLEIRKYC 403

Query: 288 -SVRGRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDE 346
             V  +I V++D G++RGTDV+KAL LGA AV +GR  ++GL   G +GV R   +L  E
Sbjct: 404 PEVFDQIEVWVDGGIKRGTDVIKALCLGAKAVGVGRAALYGLGAGGWKGVERTFEILNGE 463

Query: 347 FKLAMQLCGCQKVSDI 362
               M+L G + V+D+
Sbjct: 464 MATCMKLLGAKTVADL 479

emb|CAE41956.1| lactate dehydrogenase [Bordetella pertussis Tohama I]
ref|NP_880392.1| lactate dehydrogenase [Bordetella pertussis Tohama I]
(398 aa)

Score: 197 bits (501), Expect: 4.83627e-49
Length: 369, Idn/Pos/Gap = 128/187/25 (34%/50%/6%)

Query:  22 FAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGIDLSF  81
           +A+  LP  ++ +   G +DE  L  N  +   LR  PRV+ DVSR + +    G   S 
Sbjct:  20 WARKALPKGLFEFVDRGTEDEFLLSRNRRSLDELRLLPRVMRDVSRRNCSTHYFGQASSM  79

Query:  82 PLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFFQLYV 141
           P+++APT    +   EGE   A+A AR G    LS+ +  S+E VA    G   +FQLY+
Sbjct:  80 PMIIAPTGAAGLLAYEGEYLMAKAAARAGIPFVLSTASIVSMERVAQ--AGGDLWFQLYM 137

Query: 142 YKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANFADMKD-- 199
             D   + RL+ RA  AG+RA+ +T+DTP    RE ++RN F LP  +S  N  D+    
Sbjct: 138 LPDLGASYRLMDRARNAGYRALMVTLDTPVSPNREYNVRNHFTLPMQISSRNALDVMRRP 197

Query: 200 ------FAQVKGGAGASGLASY---VASLIDAS------------LNWNDIAWLKSITRL 238
                 F +     G   L +Y       +DAS            + W  +  L+   R 
Sbjct: 198 AWIWNVFFRYLLRNGVPMLENYPDEYRQRLDASGKGRMSLPKTDSITWESLRALRRHWRG 257

Query: 239 PILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFID 298
           P++ KG++  EDA+ A   G D I +SNHG R  D     I+ L  +   +  +  VF+D
Sbjct: 258 PLIAKGILHPEDARMARDCGVDAIVVSNHGGRNFDAAATPIEALPRIVDEIADKAEVFVD 317

Query: 299 SGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQK 358
           SG RRG DV KALALGA  VL+GR  +WG+A  GE G    L L+++E   +M   GC+ 
Sbjct: 318 SGFRRGVDVAKALALGARGVLLGRAPLWGVASAGEPGALHALELMREELLRSMAFLGCES 377

Query: 359 VSDIRRDLV 367
           ++ + R L+
Sbjct: 378 LAALDRGLL 386

gb|AAC77479.1| unknown [Rhodococcus erythropolis]
(392 aa)

Score: 197 bits (500), Expect: 6.42265e-49
Length: 379, Idn/Pos/Gap = 132/202/25 (34%/53%/6%)

Query:  16 LAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVM  75
           +AE    AK RLP  VY    +G++   T+ DN  AF  L F P       + +++  +M
Sbjct:  10 VAEAQRRAKKRLPKSVYAALVAGSEKGLTVDDNVAAFSELGFAPHAAGLSDKREMSTTIM  69

Query:  76 GIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPK 135
           G D+S P+M++PT +Q + HP+GE+A ARA A  GT +GLSS+A+ S+E+VAA  P +  
Sbjct:  70 GQDISLPVMISPTGVQAV-HPDGEVAVARAAAARGTAIGLSSFASKSIEEVAAANPQV-- 126

Query: 136 FFQLYVYKDRAITERLVRRAERAGFRAIALTVD-TPQLGR--------READIRNQFQLP 186
           FFQ+Y    R +  + + RA  AG + + +T D +   GR         + D++  FQ  
Sbjct: 127 FFQMYWVGSRDVLLQRMERARAAGAKGLIITTDWSFSYGRDWGSPSIPEKMDLKAMFQFA 186

Query: 187 PH--------LSLANFADMKDFAQ----VKGGAGASGLASYVASLIDASLNWNDIAWLKS 234
           P         L  A    + D         G    +   +Y   +      W DIAWL+ 
Sbjct: 187 PEGIMRPKWLLEFAKTGKIPDLTTPNLAAPGQPAPTFFGAYGEWMQTPLPTWEDIAWLRE 246

Query: 235 ITRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIP 294
               P +LKG++  +DA+RA+  G   I +SNHG   LDG  A I  L  +A++V  ++ 
Sbjct: 247 QWGGPFMLKGIMRIDDAKRAVDAGVSAISVSNHGGNNLDGTPAPIRVLPGIAEAVGDQVE 306

Query: 295 VFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLC 354
           V +D G+RRG DVVKALALGA AV++GR  +WGL+ +G+ GV  +L L++      +   
Sbjct: 307 VVLDGGIRRGGDVVKALALGAKAVMLGRAYLWGLSANGQAGVENVLDLMRMGIDSGLMGL 366

Query: 355 GCQKVSDIR-RDLVVRDAF 372
           G   ++++   DLV+ + F
Sbjct: 367 GHSSITELSPADLVIPEGF 385

ref|ZP_00305147.1| COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Novosphingobium aromaticivorans DSM 12444]
(361 aa)

Score: 196 bits (498), Expect: 9.11816e-49
Length: 356, Idn/Pos/Gap = 121/190/23 (33%/53%/6%)

Query:  14 LNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQ  73
           L++ E+   A+  +P   Y  + +    E+TL D+  A++ +  RPR L+DVS +D +  
Sbjct:  16 LDVGEFRAAAEPMMPD-PYRNFVNNVGMERTLHDDIAAWQAMHLRPRALVDVSHIDTSAT  74

Query:  74 VMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGL 133
           V+G  ++ P+M AP     +  PEGE+ATAR     GT+  LS   T   E V A   G 
Sbjct:  75 VLGQQIAMPIMTAPFVGSTLVDPEGEVATARGAVAAGTITTLSMMGTRPPEAVGAVASG- 133

Query: 134 PKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIR-------NQFQLP 186
             + Q+Y  +DR + + ++ RA  AG  A+  TVD P +      +R        ++Q P
Sbjct: 134 RYWQQIYFMRDRGVVKDVIERAVAAGASALCFTVDLPVMPAFPRPMRLAAQALFQRWQEP 193

Query: 187 PHLSLANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVV 246
            H+  A    ++D+A    GA          +  DA+  W D+ W+++++ LP++LKGV+
Sbjct: 194 EHVMYA----VRDYADRPMGA----------TFPDAAATWADVEWMRTLSNLPLILKGVI 239

Query: 247 TAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTD 306
             +DA RA  +GA  + +SNH  + L         L  + ++V   I V+ DSG+R G D
Sbjct: 240 RTDDAARARDHGASALIVSNHAGQGLRHSQPVAHALPAIVEAVGRDIEVYADSGIRTGAD 299

Query: 307 VVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDI 362
           V++ALALGA AVL+GRP++WGL   G +GV R+L LL+ E    M + G   +  I
Sbjct: 300 VLRALALGARAVLVGRPVLWGLTTGGSQGVERVLKLLQAELAEIMAITGASSIGAI 355

ref|NP_885118.1| putative L-lactate dehydrogenase [Bordetella parapertussis 12822]
emb|CAE38218.1| putative L-lactate dehydrogenase [Bordetella parapertussis]
(402 aa)

Score: 196 bits (498), Expect: 1.09554e-48
Length: 378, Idn/Pos/Gap = 135/195/25 (35%/51%/6%)

Query:  14 LNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQ  73
           L+L ++   A+ RLP  ++GY A  A+D Q L DN  AF    F PRVL+DVS      +
Sbjct:  27 LSLNDFEAAARRRLPRPIFGYVAGAAEDNQALDDNRRAFAEYGFLPRVLVDVSARHTRTE  86

Query:  74 VMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGL 133
           + G + + P  VAP  +  ++   G++  ARA    G    +S  +   LE+VA   PG 
Sbjct:  87 LFGQEWAAPFGVAPMGISALSAYRGDIVLARAARAAGIPAIMSGSSLIPLEEVARQAPG- 145

Query: 134 PKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLP--PHLSL 191
             +FQ Y+  D A  + LV R  RAG+R + LTVD P    RE ++R  F  P  P L L
Sbjct: 146 -TWFQAYLPGDPARIDALVERVARAGYRTLVLTVDIPVSANRENNVRTGFSTPLKPGLRL 204

Query: 192 A------------NFA------DMKDFAQVKGGAGASGLASYVASLIDAS--LNWNDIAW 231
           A             F        M  F       GA  L++ V     A   L+W+ +  
Sbjct: 205 AWDGLSRPRWLTGTFLRTLLAHGMPHFENSFATRGAPILSANVLRDFSARDHLDWSHVQR 264

Query: 232 LKSITRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRG 291
           ++   R  +++KG++   DA  A  +GADGI +SNHG RQLDG  A +  L ++A++  G
Sbjct: 265 IRRSWRGELVIKGIMHPRDAALARAHGADGIIVSNHGGRQLDGACAPLRVLPDIAEAA-G 323

Query: 292 RIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAM 351
            + V +DSG+RRG DV+KALALGA  V +GRP  +  AV GE GV   + LL++E    M
Sbjct: 324 AMAVMMDSGIRRGGDVLKALALGARFVFLGRPFNYAAAVGGEAGVAHAIGLLREEIDRNM 383

Query: 352 QLCGCQKVSDIRRDLVVR 369
            + G  + + +   L+ R
Sbjct: 384 AMLGVTRCTAMAPGLLRR 401

ref|NP_739372.1| putative L-lactate dehydrogenase [Corynebacterium efficiens YS-314]
dbj|BAC19572.1| putative L-lactate dehydrogenase [Corynebacterium efficiens YS-314]
(417 aa)

Score: 194 bits (494), Expect: 2.5874e-48
Length: 379, Idn/Pos/Gap = 131/192/21 (34%/50%/5%)

Query:   3 EKPAVNPATQPLN--LAEYHL--FAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFR  58
           +KP +N   + L+  L  Y L   AK R PA  + Y    A+ E +++   EAF  + F 
Sbjct:  19 KKPELNAKKRRLDSALTIYDLRKIAKRRTPAAAFDYTDGAAEAELSIKRAREAFENIEFH  78

Query:  59 PRVLIDVSRVDITKQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSW 118
           P +L     VD + Q++G   + P  +APT   R+   EGE+A A A    G    LS+ 
Sbjct:  79 PDILKPAENVDPSTQILGGHSALPFGIAPTGFTRLMQTEGEIAGAGAAGAAGIPFTLSTL 138

Query: 119 ATTSLEDVAAHVPGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREAD 178
            TTS+EDV A  P    +FQLYV +DR I+  LV RA  AGF  +  TVDTP  G R  D
Sbjct: 139 GTTSIEDVKATNPQGRNWFQLYVMRDREISYGLVERAAAAGFDTLMFTVDTPIAGYRIRD 198

Query: 179 IRNQFQLPPHLSLANFAD---------------MKDFAQVKGGAGASGLASYVASLIDAS 223
            RN F +PP L+     +                 +FA +    G  G    + S +D +
Sbjct: 199 TRNGFSIPPQLTPGTVLNAIPRPWWWIDFLTTPTLEFASLSSTGGTVG--DLLNSAMDPT 256

Query: 224 LNWNDIAWLKSITRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLE 283
           +++ D+  ++ +    +L+KGV    DA + L+ G DG+ +SNHG RQLD        L 
Sbjct: 257 ISYEDLKVIREMWPGKLLVKGVQNVPDAVKLLEGGVDGLILSNHGGRQLDRAPVPFHLLP 316

Query: 284 EVAQSVRGRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLL 343
           +V + V     + ID+G+  G D+V A+ALGAD  LIGR  ++GL   G +GV R + +L
Sbjct: 317 QVRREVGSEPTIMIDTGIMNGADIVAAIALGADFTLIGRAYLYGLMAGGRQGVDRTIEIL 376

Query: 344 KDEFKLAMQLCGCQKVSDI 362
           + E    M L G   + ++
Sbjct: 377 RTEITRTMALLGVSTLDEL 395

ref|ZP_00188684.1| COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Rubrobacter xylanophilus DSM 9941]
(400 aa)

Score: 194 bits (494), Expect: 2.65298e-48
Length: 383, Idn/Pos/Gap = 138/209/29 (36%/54%/7%)

Query:  15 NLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQV  74
           ++AE H  A+ RLP  VY    +G +   TLRDN  AF  L   PR++      +++ +V
Sbjct:  10 SVAEAHRRARRRLPRSVYKALLAGTEKGLTLRDNVAAFDELGLVPRLVGAPGGFELSTRV  69

Query:  75 MGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLP 134
           MG ++S P++V+PT +Q + HPEGELA ARA A  GT MGLSS+A+  +E+V A  P   
Sbjct:  70 MGQEVSLPVLVSPTGVQAV-HPEGELAVARAAASRGTAMGLSSFASKPVEEVVAANP--K 126

Query: 135 KFFQLYVYKDRAITERLVRRAERAGFRAIALTVD----------TPQLGRREADIRNQFQ 184
            FFQ Y    R    R++ RA  AG   + LT+D          +P++  +  D+R   +
Sbjct: 127 TFFQTYWVGGRDRMLRVLERAREAGAAGLILTLDWSFSHSRDWGSPRIPDK-IDLRTALR 185

Query: 185 LPPHLS-----LANFADMK--------DFAQVKGGAGASGLASYVASLIDASLNWNDIAW 231
             P ++     L  +A  +        + A        +   +Y   +      W D+AW
Sbjct: 186 FAPEVAGRPGWLLRYARARRLPELTVPNMAPSPKDPAPTFFGAYAEWMQTPPPTWEDVAW 245

Query: 232 LKSITRLPILLKGVVTAEDAQRALQ-YGADGIWISNHGARQLDGVTATIDCLEEVAQSVR 290
           L+     P +LKGV+ A++A RA++  G   + +SNHG   +DG+ A++  L  VA++V 
Sbjct: 246 LRGRWEGPFMLKGVMRADEALRAVEGAGVTAVSVSNHGGNNIDGLPASVRALPAVAEAVG 305

Query: 291 GRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLA 350
            R  V +D G+RRG+DVVKALALGA AV+IGR  +WGLA  G+ GV  +L +L+   +  
Sbjct: 306 DRAEVLLDGGIRRGSDVVKALALGARAVMIGRAYLWGLAAGGQAGVENVLDILRAGVEST 365

Query: 351 MQLCGCQKVSDI-RRDLVVRDAF 372
           ++  G   V ++ R DLVV + F
Sbjct: 366 LRGVGKGSVHEVGREDLVVPEGF 388

gb|EAA67845.1| hypothetical protein FG01027.1 [Gibberella zeae PH-1]
ref|XP_381203.1| hypothetical protein FG01027.1 [Gibberella zeae PH-1]
(488 aa)

Score: 194 bits (493), Expect: 3.73511e-48
Length: 365, Idn/Pos/Gap = 125/188/23 (34%/51%/6%)

Query:   9 PATQPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRV  68
           P    +NL E    A  R+    + YY S ADD  +   N   F+ +  RPRV +D +  
Sbjct: 104 PLASLMNLDEIEQEATKRISKKAWAYYFSAADDLFSKSYNNHVFKNILIRPRVFVDCTAC 163

Query:  69 DITKQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAA 128
           D +  ++G  +  P+ V+P AM R+AHP+GE   A+A AR G +  +S+ A+ + E +  
Sbjct: 164 DTSTTLIGNKVGLPIFVSPAAMARLAHPDGEQGIAKACARFGAMQIVSNNASMTPEQIIE 223

Query: 129 HV-PGLPKFFQLYVYKDRAITERLVRR--AERAGFRAIALTVDTPQLGRREADIRNQFQL 185
              PG    +QLYV   R  +E +++R  + R  ++ I LT+D P  G+RE D +  F  
Sbjct: 224 GAKPGQIFGWQLYVQNQRDKSEAMLKRINSMRDYYKFICLTLDAPVPGKRELDEKQNFDY 283

Query: 186 --PPHLSLANFADMKDFAQVKGGAGASGLASYVASLIDASLNW-NDIAWLKSITRLPILL 242
             P   S           + K GAG  G   +  +  D  L W   + WL + T LPI+L
Sbjct: 284 SEPSPAS----------GESKPGAGGVGQQLFFGTAAD--LTWKTTLPWLAAHTDLPIVL 331

Query: 243 KGVVTAEDAQRALQYG--ADGIWISNHGARQLDGVTATIDCLEEVAQ---SVRGRIPVFI 297
           KG+   EDA  A +Y      I +SNHG R  D     +  L E+ +    +  ++ ++I
Sbjct: 332 KGLQAHEDAFLAAKYAPQVKAIILSNHGGRAADTAPPAMHTLLEIRKYCPEIMSKVQIWI 391

Query: 298 DSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQ 357
           D G++RGTDVVKAL LGA  V IGR  ++GL   G+ GV R L +L+ E    M+L G +
Sbjct: 392 DGGIKRGTDVVKALCLGASGVGIGRAALFGLGAGGQAGVERTLEILEAETATCMRLLGAK 451

Query: 358 KVSDI 362
            +S++
Sbjct: 452 NISEL 456

emb|CAH02583.1| unnamed protein product [Kluyveromyces lactis NRRL Y-1140]
ref|XP_452190.1| unnamed protein product [Kluyveromyces lactis]
(556 aa)

Score: 193 bits (490), Expect: 7.52817e-48
Length: 373, Idn/Pos/Gap = 118/183/28 (31%/49%/7%)

Query:   4 KPAVNPATQPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLI  63
           K  + P  +   L+++   AK  LP   + YYA+G+ DE TLR+N  A+ R+ FRP++L 
Sbjct: 173 KAKIPPLRKIFCLSDFEAVAKQVLPKSTFFYYATGSSDEYTLRENHYAYSRVFFRPKILQ 232

Query:  64 DVSRVDITKQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSL 123
           D+  VD + + +G  +  P+ +   A  R+AHP GEL    A      +  +    + S 
Sbjct: 233 DIEEVDTSTKFLGAKVDLPIYITAFAGSRLAHPMGELNLQSAAYDANVMQMVPKQNSYSH 292

Query: 124 EDVAAHVPGLPKFFQLYVYKDRAITERLVRRAERAGF----RAIALTVDTPQLGRREADI 179
           E+   HVP     +  + +  +   + L +  ERAG     + +   VD   +G RE D 
Sbjct: 293 EEFFPHVPDDQNQWLQFHFDTQEELDNLDKWVERAGTLPSAKGLFFNVDLADIGNREKDS 352

Query: 180 RNQFQLPPHLSLANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLP 239
           R +   P    L    D K  +  K                   + W+ I  +   T LP
Sbjct: 353 RQRASQPGSEYLDEMTDNKFGSHPK-------------------ITWSTIERVMKNTHLP 393

Query: 240 ILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVR-----GRIP 294
           + LKGV   ED   A Q G   + +SNHG RQLD     ++ L E  Q ++     G+I 
Sbjct: 394 VALKGVQRGEDVVIAAQKGVKAVILSNHGGRQLDFSRPPLEVLVEAKQMLKEKNLDGKIE 453

Query: 295 VFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLC 354
           +++D GVRRG+D++KAL LGA  V +GRP ++ ++  GEEGV  L ++L+ E +  M+L 
Sbjct: 454 IYLDGGVRRGSDILKALCLGATGVGMGRPFLYAMSGYGEEGVTHLFNILRTEIENNMRLL 513

Query: 355 GCQKVSDIRRDLV 367
           G  K+ D+   LV
Sbjct: 514 GVDKIEDLDESLV 526

gb|EAA60621.1| hypothetical protein AN8587.2 [Aspergillus nidulans FGSC A4]
ref|XP_412724.1| hypothetical protein AN8587.2 [Aspergillus nidulans FGSC A4]
(400 aa)

Score: 193 bits (490), Expect: 8.32095e-48
Length: 369, Idn/Pos/Gap = 131/198/20 (35%/53%/5%)

Query:  19 YHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGID  78
           +   AK RL A  +GY    A   QT  +N  AF++    P  L+  +  ++   + G +
Sbjct:  32 WEALAKERLSADSFGYVWGSAGTRQTDDNNRAAFKKWGIVPSRLVKANFTNLKTTLFGDE  91

Query:  79 LSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFFQ 138
             +PL +AP  +QR+ H EGE A A+A    G    LS+  +TSLE+VA      P+++Q
Sbjct:  92 YEYPLALAPVGVQRIFHQEGESAAAKAAGEEGVTFILSTATSTSLENVAKANRDGPRWYQ 151

Query: 139 LY--VYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLAN--- 193
           LY    +   IT  L++RA+  G++ + +T+DT  LG R +D+ N +   P L   N   
Sbjct: 152 LYWPSNEHHDITASLLKRAKENGYKVLVVTLDTYMLGWRPSDLDNGYN--PFLRNDNIGV 209

Query: 194 ---FAD--------MKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILL 242
              F+D         K  A+V+   G +            S  W DI++LK     PI+L
Sbjct: 210 EIGFSDPVFRKRFKEKHGAEVEEDVGKAAQEWAHTIFPGTSHGWEDISFLKEHWDGPIVL 269

Query: 243 KGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVR 302
           KG+ T  DA+RA++ G  GI +SNHG RQ DG   +++ L E+  +V  +I V  DSGVR
Sbjct: 270 KGIQTVADAKRAIEVGVHGIVVSNHGGRQQDGGVGSLEVLPEIVDAVGQKIEVLFDSGVR 329

Query: 303 RGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSD- 361
            G D+ KALALGA  VL+GRP V+GLA+ G+EGV  ++  L  + +L + L G   +S  
Sbjct: 330 CGADIAKALALGAKMVLVGRPYVYGLAISGQEGVRHVIRSLLGDLQLILHLSGVPDISSR 389

Query: 362 -IRRDLVVR 369
            + R+++ R
Sbjct: 390 KLNREVLRR 398

emb|CAE33387.1| putative L-lactate dehydrogenase [Bordetella bronchiseptica RB50]
ref|NP_889431.1| putative L-lactate dehydrogenase [Bordetella bronchiseptica RB50]
(402 aa)

Score: 193 bits (490), Expect: 8.96987e-48
Length: 378, Idn/Pos/Gap = 134/194/25 (35%/51%/6%)

Query:  14 LNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQ  73
           L+L ++   A+ RLP  ++GY A  A+D Q   DN  AF    F PRVL+DVS      +
Sbjct:  27 LSLNDFEAAARRRLPRPIFGYVAGAAEDNQAHDDNRRAFAEYGFLPRVLVDVSARHTRTE  86

Query:  74 VMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGL 133
           + G + + P  VAP  +  ++   G++  ARA    G    +S  +   LE+VA   PG 
Sbjct:  87 LFGQEWAAPFGVAPMGISALSAYRGDIVLARAARAAGIPAIMSGSSLIPLEEVARQAPG- 145

Query: 134 PKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLP--PHLSL 191
             +FQ Y+  D A  + LV R  RAG+R + LTVD P    RE ++R  F  P  P L L
Sbjct: 146 -TWFQAYLPGDPARIDALVERVARAGYRTLVLTVDIPVSANRENNVRTGFSTPLKPGLRL 204

Query: 192 A------------NFA------DMKDFAQVKGGAGASGLASYVASLIDAS--LNWNDIAW 231
           A             F        M  F       GA  L++ V     A   L+W+ +  
Sbjct: 205 AWDGLSRPRWLAGTFLRTLLAHGMPRFENSFATRGAPILSANVLRDFSARDHLDWSHVQR 264

Query: 232 LKSITRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRG 291
           ++   R  +++KG++   DA  A  +GADGI +SNHG RQLDG  A +  L ++A++  G
Sbjct: 265 IRRSWRGELVIKGIMHPRDAALARAHGADGIIVSNHGGRQLDGACAPLRVLPDIAEAA-G 323

Query: 292 RIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAM 351
            + V +DSG+RRG DV+KALALGA  V +GRP  +  AV GE GV   + LL++E    M
Sbjct: 324 AMAVMMDSGIRRGGDVLKALALGARFVFLGRPFNYAAAVGGEAGVAHAIGLLREEIDRNM 383

Query: 352 QLCGCQKVSDIRRDLVVR 369
            + G  + + +   L+ R
Sbjct: 384 AMLGVTRCTAMAPGLLRR 401

ref|NP_963088.1| LldD1 [Mycobacterium avium subsp. paratuberculosis str. k10]
gb|AAS06704.1| LldD1 [Mycobacterium avium subsp. paratuberculosis str. k10]
(394 aa)

Score: 192 bits (487), Expect: 1.64935e-47
Length: 370, Idn/Pos/Gap = 138/200/42 (37%/54%/11%)

Query:  23 AKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGIDLSFP  82
           AK RLP  VY    + ++   T+ DN EAF  L F P V+   ++ ++T  VMG ++S P
Sbjct:  16 AKRRLPKSVYAALIAASEKGITVSDNVEAFGELGFAPHVVGAPAKRELTTTVMGQEISMP  75

Query:  83 LMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFFQLYVY 142
           ++++PT +Q +  P+GE+A ARA A  GT MGLSS+A+  +E+V A  P +  FFQ+Y  
Sbjct:  76 VLISPTGVQAV-DPDGEVAVARAAAARGTAMGLSSFASKPIEEVIAVNPKV--FFQVYWL 132

Query: 143 KDR-AITERLVRRAERAGFRAIALTVD----------TPQLGRREADIRNQFQL------ 185
             R AI ER V RA +AG   + +T D          +P++   E ++R   +L      
Sbjct: 133 GGRDAIAER-VERARQAGAVGLIVTTDWSFSHGRDWGSPKI-PEEMNLRTILRLSPEAVF 190

Query: 186 -------------PPHLSLANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWL 232
                        PP L + N          +G  G    A+Y   +      W DIAWL
Sbjct: 191 KPRWLWKFGKTLRPPELRVPNQGR-------RGEPGPPFFAAYGEWMGTPPPTWEDIAWL 243

Query: 233 KSITRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGR 292
           + +   P +LKGV+  +DA+RA+  G   I +SNHG   LDG  A+I  L  +A++V  +
Sbjct: 244 RELWGGPFMLKGVMRVDDAKRAVDAGVSAISVSNHGGNNLDGTPASIRALPAIAEAVGDQ 303

Query: 293 IPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQ 352
           I V +D GVRRG+DVVKA+ALGA AV+IGR  +WGLA  G+ GV  +L +L+     A+ 
Sbjct: 304 IEVLLDGGVRRGSDVVKAVALGARAVMIGRAYLWGLAAAGQAGVENVLDILRGGIDSALM 363

Query: 353 LCGCQKVSDI 362
             G   V D+
Sbjct: 364 GLGHSSVHDL 373

ref|YP_116429.1| putative dehydrogenase [Nocardia farcinica IFM 10152]
dbj|BAD55065.1| putative dehydrogenase [Nocardia farcinica IFM 10152]
(391 aa)

Score: 192 bits (487), Expect: 1.6771e-47
Length: 358, Idn/Pos/Gap = 126/189/17 (35%/52%/4%)

Query:  23 AKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVS---RVDITKQVMGIDL  79
           A+  L A  + Y A  A   +T   N  AF R R  PR+L   +     D++ +V+G  L
Sbjct:  34 AREVLGASEFAYVAGSASSGRTAAANRAAFDRYRIVPRMLRGATGPGNRDLSTEVLGTRL  93

Query:  80 SFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFFQL 139
           + P++ AP  +  +  P GE+  A     +G    LS+ +++++E+V A       ++QL
Sbjct:  94 AAPVLTAPIGVLELMRPGGEVTVAEVTKELGIGSVLSTASSSTIEEVGAAAGDW--WYQL 151

Query: 140 YVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHL---SLANF-- 194
           Y   D  +    V RAERAG +AI +TVDTP LG R  D+  +    P L    +AN+  
Sbjct: 152 YWPADHDLARSFVERAERAGAKAIMVTVDTPSLGWRPQDL--ELAHLPFLVGKGIANYLS 209

Query: 195 -----ADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAE 249
                A +    +    A    + ++V    + +L   DIA L+  T LPI +KG++  +
Sbjct: 210 DPVFRAKLPSPPEESEDAMRIAILTWVGLFGNHTLRPADIARLREWTDLPIAVKGILHPD 269

Query: 250 DAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVK 309
           DA+  +  GADG+ +SNHG RQ+D   A +D L  V  ++  R  V  DSG+R G+DV+ 
Sbjct: 270 DARAVIDAGADGVVVSNHGGRQVDNSIAALDALPAVVSAIGDRADVLFDSGIRTGSDVLV 329

Query: 310 ALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLV 367
           AL+LGA AVL GRP  +GL + G  GV+  L LL  +F  AM LCGC   + + R L+
Sbjct: 330 ALSLGAKAVLFGRPYAYGLGIAGRAGVHHALRLLLADFDSAMGLCGCTSAAALDRSLI 387

gb|EAK85386.1| hypothetical protein UM04504.1 [Ustilago maydis 521]
ref|XP_402119.1| hypothetical protein UM04504.1 [Ustilago maydis 521]
(421 aa)

Score: 192 bits (487), Expect: 1.82304e-47
Length: 399, Idn/Pos/Gap = 146/210/42 (36%/52%/10%)

Query:   9 PATQPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVS--  66
           P T  L L E    AK++L    Y Y A  A  E T + N +AF +    P +L DVS  
Sbjct:  22 PQTTNLKLLEQQ--AKSKLTPEAYAYVAGSASTESTAQANLDAFSKWHIVPSMLRDVSLA  79

Query:  67 RVDITKQVMGIDLSFPLMVAPTAMQRMAHP-EGELATARAVARIGTVMGLSSWATTSLED 125
             D T ++ G + S PL+VAP  +Q   H  E + ATARA A +     LSS  +  LE 
Sbjct:  80 EFDSTTRLFGREYSSPLVVAPIGVQAQLHAAEADCATARAAADLEIPFTLSSATSRPLEK 139

Query: 126 VAAHVP--------GLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREA 177
           V  H          G+  +FQLY  +D  +TE L+ RA++AG+R + +T+DT +LG   A
Sbjct: 140 VHEHAGFSKGSEEGGVDAWFQLYWPQDDELTESLLSRAKKAGYRVLVVTLDTWELGM--A 197

Query: 178 DIRNQFQLP--PHLS-------------LANFADMKDFAQV---KGGAGASGLASYVASL 219
             R++F  P  P L+             +  + + KD  +    K     + +A+     
Sbjct: 198 PKRSRFSKPYNPFLTGEGVANVFSDPVFIERYCEGKDPRRSDVSKEEITEASVAAIAQLS 257

Query: 220 IDASLNWNDIAWLKSI-TRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTAT 278
              S  W+D+A L+ +    PI+LKG+ T  DA RA++ G DG+W+SNHG RQ+DG   +
Sbjct: 258 PGVSRTWSDLALLRRLWGSNPIVLKGIQTLSDAARAVEAGMDGVWVSNHGGRQVDGAVPS 317

Query: 279 IDCLEEVAQSVRG--------RIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAV 330
           ++ L  +A+ +R         R  V  DSGVR G D++KAL LGADAV +GRP  WGLA+
Sbjct: 318 LNQLPVIAEYIRSLPLKEGEERKTVIFDSGVRCGADIMKALCLGADAVAVGRPWCWGLAL 377

Query: 331 DGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLVVR 369
           +GE+GV  +L  L  +F+L   L G Q  S + R  +VR
Sbjct: 378 NGEDGVRDVLKTLLADFELNAGLAGFQSASQLSRHALVR 416

ref|ZP_00305422.1| COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Novosphingobium aromaticivorans DSM 12444]
(381 aa)

Score: 191 bits (486), Expect: 2.56664e-47
Length: 383, Idn/Pos/Gap = 124/191/39 (32%/49%/10%)

Query:  15 NLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQV  74
           ++ ++   A+ RLP  ++ Y   G+  E TLR N E  R +  R RVL DVS +D++ ++
Sbjct:   5 SIPDFRELARRRLPHFLFEYIDGGSYSETTLRRNVEDLRDIALRQRVLRDVSGLDLSTEL  64

Query:  75 MGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLP 134
            G  ++ P+ +AP  +  M    GE    RA    G    LS+ +  SL +VA      P
Sbjct:  65 FGQKVALPVALAPIGLAGMNARRGECQAVRAAETAGIPFTLSTVSACSLAEVAG-AASKP 123

Query: 135 KFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANF 194
            +FQLY+ +DR     L++ A       +  TVD P  G R  D         H  LA  
Sbjct: 124 FWFQLYMTRDRGFMRELLQEAVELKCSTLVFTVDMPVPGSRYRDY--------HSGLAGA 175

Query: 195 ADMKD------------------------------FAQVKGGAGASGLASYVASLIDASL 224
           + MK                                 ++ G  G     +++ +  D+S+
Sbjct: 176 SGMKGALRRTLQGAMKPGWAWDVGVMGRPHGLGNVVRKLDGKTGIEDFFAWMRNNFDSSI 235

Query: 225 NWNDIAWLKSITRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEE 284
            W+D+ +++S    P+++KG++  EDA  A   GADGI +SNHG RQLDGV ++   L  
Sbjct: 236 AWSDLDFIRSEWNGPLVIKGLLDPEDAVEAANLGADGIVVSNHGGRQLDGVLSSAKALPA 295

Query: 285 VAQSVRGRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLK 344
           +A +V  R+ V  D GVR G DVV+ LALGA  VL+GR  V+ LA  G+ GV  +L L++
Sbjct: 296 IADAVGDRMTVLADGGVRSGLDVVRLLALGAKGVLLGRAWVFALAAQGQAGVEHMLRLIE 355

Query: 345 DEFKLAMQLCGCQKVSDIRRDLV 367
            E ++AM L G + + +I R ++
Sbjct: 356 AEMRVAMTLTGVKNIGEIDRSIL 378

emb|CAD33731.1| putative FMN-dependent dehydrogenase [Escherichia coli]
(405 aa)

Score: 191 bits (486), Expect: 2.65375e-47
Length: 351, Idn/Pos/Gap = 128/182/24 (36%/51%/6%)

Query:  23 AKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVS--RVDITKQVMGIDLS  80
           AK  +    Y Y A GA DE T  +N  AF      P  L  V+   +DI   ++G  L 
Sbjct:  66 AKDVMTEAAYAYIAHGAGDEWTYHENRRAFSDYPLLPHRLSGVAAHSIDIRTDLLGHHLE 125

Query:  81 FPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFFQLY 140
            PL++AP       HPEGE+  A    + G +   S  +  SLED+A    G PK+FQLY
Sbjct: 126 HPLLIAPMGAHMFVHPEGEVIAAAGAEKAGALYESSGASNRSLEDIAKASKG-PKWFQLY 184

Query: 141 VYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLAN----FAD 196
              D  +T  L+ RA+ AG+ AI +T D    G  +A +      P   +  N    +  
Sbjct: 185 FNADAGVTRSLLERAKAAGYSAIIITADALGPGTSDAFLSMSSPFPAGATFGNHDPRYGG 244

Query: 197 MKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQRALQ 256
             DF   K                   L   DI ++K IT LP+++KG++  EDA  A+ 
Sbjct: 245 KGDFFNQK-----------------VELTPADIEFVKKITGLPVIVKGILRGEDAVVAID 287

Query: 257 YGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALALGAD 316
            GAD I +SNHG RQ+DGV + I  L+EVA  V  ++PV  DSG+RRG DVV+A++LGA 
Sbjct: 288 AGADAIQVSNHGGRQIDGVPSAISQLQEVAARVGHKVPVIFDSGIRRGIDVVRAISLGAT 347

Query: 317 AVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLV 367
           AV +GRP+++G+A  G  GV  ++  LK E + AM L G + + D+ +  +
Sbjct: 348 AVAVGRPVLYGIAAGGVGGVASVIEHLKTELRTAMLLSGARTLKDLSQGFI 398

gb|AAK44950.1| FMN-dependent alpha-hydroxy acid dehydrogenase family protein [Mycobacterium tuberculosis CDC1551]
ref|NP_335136.1| FMN-dependent alpha-hydroxy acid dehydrogenase family protein [Mycobacterium tuberculosis CDC1551]
(419 aa)

Score: 188 bits (478), Expect: 1.83885e-46
Length: 361, Idn/Pos/Gap = 134/194/24 (37%/53%/6%)

Query:  23 AKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGIDLSFP  82
           AK RLP  VY    + ++   T+ DN  AF  L F P V+    + D++  VMG ++S P
Sbjct:  16 AKRRLPKSVYSSLIAASEKGITVADNVAAFSELGFAPHVIGATDKRDLSTTVMGQEVSLP  75

Query:  83 LMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFFQLYVY 142
           ++++PT +Q +  P GE+A ARA A  GTVMGLSS+A+  +E+V A  P    FFQ+Y  
Sbjct:  76 VIISPTGVQAV-DPGGEVAVARAAAARGTVMGLSSFASKPIEEVIAANP--KTFFQVYWQ 132

Query: 143 KDRAITERLVRRAERAGFRAIALTVD-TPQLGR--------READIRNQFQLPPHLS--- 190
             R      V RA +AG   + +T D T   GR         E +++   +L P      
Sbjct: 133 GGRDALAERVERARQAGAVGLVVTTDWTFSHGRDWGSPKIPEEMNLKTILRLSPEAITRP 192

Query: 191 --LANFA------DMKDFAQ-VKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPIL 241
             L  FA      D++   Q  +G  G    A+Y   +      W DI WL+ +   P +
Sbjct: 193 RWLWKFAKTLRPPDLRVPNQGRRGEPGPPFFAAYGEWMATPPPTWEDIGWLRELWGGPFM 252

Query: 242 LKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGV 301
           LKGV+  +DA+RA+  G   I +SNHG   LDG  A+I  L  V+ +V  ++ V +D G+
Sbjct: 253 LKGVMRVDDAKRAVDAGVSAISVSNHGGNNLDGTPASIRALPAVSAAVGDQVEVLLDGGI 312

Query: 302 RRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSD 361
           RRG+DVVKA+ALGA AV+IGR  +WGLA +G+ GV  +L +L+     A+   G   V D
Sbjct: 313 RRGSDVVKAVALGARAVMIGRAYLWGLAANGQAGVENVLDILRGGIDSALMGLGHASVHD 372

Query: 362 I 362
           +
Sbjct: 373 L 373

ref|YP_119419.1| putative dehydrogenase [Nocardia farcinica IFM 10152]
dbj|BAD58055.1| putative dehydrogenase [Nocardia farcinica IFM 10152]
(400 aa)

Score: 188 bits (478), Expect: 2.30348e-46
Length: 381, Idn/Pos/Gap = 139/207/29 (36%/54%/7%)

Query:  16 LAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVM  75
           +AE    AK RLP  VYG   +G++  QT+ DNE AF  L F P V   +   D +  V+
Sbjct:   8 VAEAQRRAKKRLPKSVYGALIAGSERGQTIADNERAFTELGFAPHVAGPIGERDQSTTVL  67

Query:  76 GIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPK 135
           G  +S P++++PT +Q + HP+GE+A ARA A  G  MGLSS+A+  +E+V A  P    
Sbjct:  68 GQQISMPVLISPTGVQAV-HPDGEVAVARAAAARGIAMGLSSFASKPIEEVVAANPA--T 124

Query: 136 FFQLYVYKDR-AITERLVRRAERAGFRAIALTVD----------TPQLGRREADIRNQFQ 184
           FFQLY    +  I+ER+ R A       + LT+D          +P++  +  D++   +
Sbjct: 125 FFQLYWCGSKDEISERMARAAAAGAV-GLILTLDWSFSHGRDWGSPEIPEK-LDLKTMLK 182

Query: 185 LPPHLS-----LANFAD---MKDFA----QVKGGAGASGLASYVASLIDASLNWNDIAWL 232
             P        LA +A    + D       V GG       +Y   +   + +W+D+AW+
Sbjct: 183 FAPQTLVRPRWLATYAKSGRIPDLTAPNMSVGGGPAPGFFGAYGQWMGTPAPDWDDVAWI 242

Query: 233 KSITRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGR 292
                 P++LKGV+  +DA+RA+  G   I +SNHG   LDG  A +  L  +A +V   
Sbjct: 243 CEQWNGPVMLKGVIRVDDARRAVDAGVAAISVSNHGGNNLDGTPAAVRALPVIADTVGHE 302

Query: 293 IPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQ 352
           I V +D G+RRG+DVVKA+ALGA AV+IGR  +WGLA +G+ GV  +L +L+     A+ 
Sbjct: 303 IEVLLDGGIRRGSDVVKAVALGARAVMIGRAYLWGLAANGQAGVENVLDILRGGIDSALL 362

Query: 353 LCGCQKVSDIRR-DLVVRDAF 372
                KV+D+ R D+VV + F
Sbjct: 363 GLRKTKVTDLDRGDIVVPEGF 383

ref|YP_118443.1| putative dehydrogenase [Nocardia farcinica IFM 10152]
dbj|BAD57079.1| putative dehydrogenase [Nocardia farcinica IFM 10152]
(390 aa)

Score: 188 bits (477), Expect: 2.7676e-46
Length: 380, Idn/Pos/Gap = 134/197/27 (35%/51%/7%)

Query:  16 LAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVM  75
           +AE    AK R+P  VY    +G+    TL DN  AF  L FRP +            V+
Sbjct:  11 VAEAQERAKKRVPEPVYRALLAGSQAGVTLADNTAAFAELGFRPHIADLPPVRSQATTVL  70

Query:  76 GIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPK 135
           G ++S P++++PT +Q +  P GE+  ARA A  GT MGLSS+A+  +EDV A    +  
Sbjct:  71 GQEISLPVIISPTGVQAV-DPHGEVGVARAAAASGTAMGLSSFASKPIEDVIAANEKV-- 127

Query: 136 FFQLYVYKDRAITERLVRRAERAGFRAIALTVD----------TPQLGRREADIRNQFQL 185
           FFQ+Y   D+      + RA+RAG + + +T+D          +P L  R  D+R   + 
Sbjct: 128 FFQIYWLGDKDAMLARLDRAKRAGAKGLIVTLDWVFATARDWGSPPLPER-IDVRTAIRF 186

Query: 186 PPH-----------LSLANFADMKDFAQVKGG-AGASGLASYVASLIDASLNWNDIAWLK 233
            P            L      D+     V  G  G +   +Y   +      W D+AWL+
Sbjct: 187 APRVLTRPGWLWRFLRAGALPDLTTPNLVGAGETGPTFFGAYGEWMGTPPPTWADLAWLR 246

Query: 234 SITRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRI 293
                P+L+KG+   +DA+RA+  GA  I +SNHG   LD   A I  L  +A++V  ++
Sbjct: 247 EQWSGPLLIKGITHPDDARRAVDIGATAISVSNHGGNNLDSTPAAIRLLPGIAEAVGDQL 306

Query: 294 PVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQL 353
            V +D GVRRG+DVVKA+ALGA AV+IGRP +WG+A  GE GV+ +L +L+      +  
Sbjct: 307 EVLLDGGVRRGSDVVKAVALGARAVMIGRPYLWGMAAGGERGVHNVLEILRQGIDSTLYG 366

Query: 354 CGCQKVSDIR-RDLVVRDAF 372
            G   + D+R  D++V D F
Sbjct: 367 LGRADIHDVRAEDVLVPDGF 386

ref|YP_005713.1| lactate 2-monooxygenase [Thermus thermophilus HB27]
gb|AAS82086.1| lactate 2-monooxygenase [Thermus thermophilus HB27]
(430 aa)

Score: 188 bits (477), Expect: 2.98344e-46
Length: 353, Idn/Pos/Gap = 134/183/39 (37%/51%/11%)

Query:  23 AKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGIDLSFP  82
           A+ R+    + Y A GA  E T+  N EAFRRL   PR+L       +  ++ G   + P
Sbjct:  33 AQKRMSPEAFAYVAGGAGLEWTMEANREAFRRLALLPRMLRGTKPPGLGVELWGRRWAAP  92

Query:  83 LMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVA----AHVPGLPKFFQ 138
           L + P  +  +AHPE ELA  RA A+ G    +S+ A+  LE V     A  P  P FFQ
Sbjct:  93 LFLCPIGVLELAHPEAELAAVRAAAKRGLPFMVSNQASHPLERVVEAAKAVNPEAPVFFQ 152

Query: 139 LYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREAD--------IRNQ-------- 182
           LY   D    E  +RRAE+AG   + LTVDT QLG R  D        ++ Q        
Sbjct: 153 LYHSTDPRAVESFLRRAEKAGCAGVVLTVDTVQLGWRPRDLDLGHLPFLKGQGLAVYLTD 212

Query: 183 ---------------FQLPPHLSLANFADMKDFAQVKGGAG----ASGLASYVASLIDAS 223
                          F+  P L+L            + G         +  +VA+     
Sbjct: 213 PAFLGALDEPLEGPAFRPKPTLALLRNLLALRRTGRRYGLSLIQMQKAVRRFVATYSYPE 272

Query: 224 LNWNDIAWLKSITRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLE 283
           L+W ++  ++  T LP+LLKG++  EDA RA++ G DG+++SNHG RQ+DG  A +  L 
Sbjct: 273 LSWEEVRRVRESTALPLLLKGILHPEDALRAVELGVDGVYVSNHGGRQVDGSLAALHALP 332

Query: 284 EVAQSVRGRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGV 336
           +V Q+V GR+PV +DSGVR G D VKALALGA AV +GRP V+ LA+ GEEGV
Sbjct: 333 QVVQAVEGRVPVLMDSGVRTGADAVKALALGARAVGLGRPYVYALALGGEEGV 385

emb|CAC19728.1| SPAPB1A11.03 [Schizosaccharomyces pombe]
ref|NP_593999.1| putative FMN dependent dehydrogenase; similar to lactate dehydrogenase [Schizosaccharomyces pombe]
(407 aa)

Score: 187 bits (476), Expect: 3.11053e-46
Length: 366, Idn/Pos/Gap = 124/196/18 (33%/53%/4%)

Query:  22 FAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGIDLSF  81
            A  R+     GY    A   +T   N E+F++    P  LI     D++  V G    F
Sbjct:  42 LAVERMTKDAAGYVYGCAGKRETYDKNMESFKKWSIIPNRLIKSGFPDLSTTVFGQKYPF 101

Query:  82 PLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDV-AAHVPGLPKFFQLY 140
           P+ +AP  +Q++ +PEGE  +  A  R      +S+ + TS ED+  A  PG  +++QLY
Sbjct: 102 PIALAPVGVQKIFNPEGESGSCAAATREHIPYIISTASATSFEDIEKASGPG-ERWYQLY 160

Query: 141 VYKD--RAITERLVRRAERAGFRAIALTVDTPQLGRREADIRN---QFQLPPHLSLAN-F 194
              +  + IT  L+ RA++ G R + +T+DT  LG R +D+ N    F  P  + + + F
Sbjct: 161 WPSNDHQDITISLLNRAKKTGCRVLIVTLDTFILGWRPSDMDNGYDPFLNPDSIGVEHGF 220

Query: 195 AD---MKDFAQVKGGAGASGL---ASYVASLI--DASLNWNDIAWLKSITRLPILLKGVV 246
           +D    K F +  G      +   A   A ++    S +W D+ +L+     PI+LKG++
Sbjct: 221 SDPVFRKQFKEKHGVEVEENMLEAAKEFAGIVFPGISHDWEDLKFLRKHWDGPIVLKGIM 280

Query: 247 TAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTD 306
              DA++A++YG  GI +SNHG RQ DG  A++  L ++  +V  ++ V  DSGVR G D
Sbjct: 281 NVPDAKKAVEYGMQGIVVSNHGGRQQDGGVASLTMLPKIVDAVGDKLDVLFDSGVRSGAD 340

Query: 307 VVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKV--SDIRR 364
           + KALALGA  VLIGRP V+GLA++G  GV  ++  L  + +L + L G   V   D+ R
Sbjct: 341 IAKALALGAKMVLIGRPYVYGLALEGSSGVSHVIRCLLGDLELTLHLSGIVSVKPKDLNR 400

Query: 365 DLVVRD 370
           D++ ++
Sbjct: 401 DVLYKE 406

ref|NP_215208.1| POSSIBLE L-LACTATE DEHYDROGENASE (CYTOCHROME) LLDD1 [Mycobacterium tuberculosis H37Rv]
ref|NP_854371.1| POSSIBLE L-LACTATE DEHYDROGENASE (CYTOCHROME) LLDD1 [Mycobacterium bovis AF2122/97]
emb|CAB06457.1| POSSIBLE L-LACTATE DEHYDROGENASE (CYTOCHROME) LLDD1 [Mycobacterium tuberculosis H37Rv]
emb|CAD93575.1| POSSIBLE L-LACTATE DEHYDROGENASE (CYTOCHROME) LLDD1 [Mycobacterium bovis AF2122/97]
pir||A70641 probable lldD1 protein - Mycobacterium tuberculosis (strain H37RV)
(396 aa)

Score: 187 bits (476), Expect: 3.29762e-46
Length: 372, Idn/Pos/Gap = 137/199/25 (36%/53%/6%)

Query:  23 AKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGIDLSFP  82
           AK RLP  VY    + ++   T+ DN  AF  L F P V+    + D++  VMG ++S P
Sbjct:  16 AKRRLPKSVYSSLIAASEKGITVADNVAAFSELGFAPHVIGATDKRDLSTTVMGQEVSLP  75

Query:  83 LMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFFQLYVY 142
           ++++PT +Q +  P GE+A ARA A  GTVMGLSS+A+  +E+V A  P    FFQ+Y  
Sbjct:  76 VIISPTGVQAV-DPGGEVAVARAAAARGTVMGLSSFASKPIEEVIAANP--KTFFQVYWQ 132

Query: 143 KDRAITERLVRRAERAGFRAIALTVD-TPQLGR--------READIRNQFQLPPHLS--- 190
             R      V RA +AG   + +T D T   GR         E +++   +L P      
Sbjct: 133 GGRDALAERVERARQAGAVGLVVTTDWTFSHGRDWGSPKIPEEMNLKTILRLSPEAITRP 192

Query: 191 --LANFA------DMKDFAQ-VKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPIL 241
             L  FA      D++   Q  +G  G    A+Y   +      W DI WL+ +   P +
Sbjct: 193 RWLWKFAKTLRPPDLRVPNQGRRGEPGPPFFAAYGEWMATPPPTWEDIGWLRELWGGPFM 252

Query: 242 LKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGV 301
           LKGV+  +DA+RA+  G   I +SNHG   LDG  A+I  L  V+ +V  ++ V +D G+
Sbjct: 253 LKGVMRVDDAKRAVDAGVSAISVSNHGGNNLDGTPASIRALPAVSAAVGDQVEVLLDGGI 312

Query: 302 RRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSD 361
           RRG+DVVKA+ALGA AV+IGR  +WGLA +G+ GV  +L +L+     A+   G   V D
Sbjct: 313 RRGSDVVKAVALGARAVMIGRAYLWGLAANGQAGVENVLDILRGGIDSALMGLGHASVHD 372

Query: 362 IR-RDLVVRDAF 372
           +   D++V   F
Sbjct: 373 LSPADILVPTGF 384

emb|CAC46871.1| PUTATIVE L-LACTATE DEHYDROGENASE (CYTOCHROME) PROTEIN [Sinorhizobium meliloti]
ref|NP_386398.1| PUTATIVE L-LACTATE DEHYDROGENASE (CYTOCHROME) PROTEIN [Sinorhizobium meliloti 1021]
(364 aa)

Score: 187 bits (475), Expect: 4.80026e-46
Length: 361, Idn/Pos/Gap = 127/182/31 (35%/50%/8%)

Query:  10 ATQPLNLAEYHLF------AKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLI  63
           AT P +L ++         A+  LP   +     GA+ E TL+ N  A   + F+PRVL 
Sbjct:   7 ATCPPHLGDFESLQEIIQKAQGALPKEKWDSLVGGAETETTLKRNRLAIDSIAFKPRVLR  66

Query:  64 DVSRVDITKQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSL 123
           +VS VD++ +  G  L  P+ +APT    +  P G  A A      G    LSS   T L
Sbjct:  67 NVSVVDLSIEHFGRRLRLPIFLAPTGPLNLFGPGGGAAVASGAQVFGVAHMLSS-GCTPL 125

Query: 124 EDVAAHVPGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQF 183
           E VA   P   +  QLYV  D A   + V RA  +G  AI LTVD+  L RR+ DI N+ 
Sbjct: 126 ESVAEAAPSALRMAQLYVRGDDASVHKYVGRALASGCAAICLTVDSAVLARRDRDIANRH 185

Query: 184 QLPPHLSLANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLK 243
           +                         +GL  +      A L+W  +  +K    +P++LK
Sbjct: 186 R------------------------TAGLGKWPGQAYQAGLDWRTVKLIKDSYDIPLVLK 221

Query: 244 GVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRR 303
           G+ T EDA+ A+ +G D I++SNHG RQLD    T+D L E+  +V G+  V +D G  R
Sbjct: 222 GIATVEDARIAVDHGVDWIYVSNHGGRQLDHGRGTMDVLPEIIDAVGGQAKVMVDGGFCR 281

Query: 304 GTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIR 363
           GTD++KALA+GA+ V +GR   + LA  GE  + R+L L++DE   +M L G   + D+ 
Sbjct: 282 GTDIIKALAIGANLVGLGRMQCYALAAGGEAAIIRMLELIEDEMLRSMALLGVPTIGDLD 341

Query: 364 R 364
           R
Sbjct: 342 R 342

ref|XP_588492.1| PREDICTED: similar to hydroxyacid oxidase 1, partial [Bos taurus]
(189 aa)

Score: 186 bits (473), Expect: 6.87197e-46
Length: 172, Idn/Pos/Gap = 92/127/3 (53%/73%/1%)

Query: 109 IGTVMGLSSWATTSLEDVAAHVPGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVD 168
           +GT M LSSWAT+S+E+VA   P   ++ QLY+YKDR +T++LVRRAER G++AI +TVD
Sbjct:   4 LGTGMMLSSWATSSIEEVAEAGPEAIRWLQLYIYKDREVTKQLVRRAERMGYKAIFVTVD  63

Query: 169 TPQLGRREADIRNQFQLPPHLSLANFADMKD--FAQVKGGAGASGLASYVASLIDASLNW 226
           TP LG R  D+RN+F++PP L + NF +  D  F+  +     SGLA+YVA  ID S++W
Sbjct:  64 TPYLGNRFDDVRNRFKMPPQLRMKNF-ETNDLAFSPKENFGDKSGLAAYVAKAIDPSISW 122

Query: 227 NDIAWLKSITRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTAT 278
            DI WL+ +T LPI+ KG++  +DA+ A+++G DGI +SNHGARQLDGV AT
Sbjct: 123 EDIKWLRRLTSLPIVAKGILRGDDAKAAVKHGLDGILVSNHGARQLDGVPAT 174

ref|ZP_00281523.1| COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Burkholderia fungorum LB400]
(415 aa)

Score: 186 bits (472), Expect: 9.43582e-46
Length: 364, Idn/Pos/Gap = 129/184/25 (35%/50%/6%)

Query:  14 LNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQ  73
           L+  ++   AK RLPA +Y + A G++D      + EAF   RF PRVL +V+RV     
Sbjct:  18 LSAHDFDALAKKRLPAPLYSFVAGGSEDHHAHVGSREAFLAYRFVPRVLCNVARVQQHVT  77

Query:  74 VMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGL 133
           V G     P  +AP     +   +G+LA AR  A     M +S  A TSLE + A     
Sbjct:  78 VFGRSYQSPFGIAPMGGVALTAYDGDLALARGAAHADIPMVVSGAALTSLEAIRAQASN- 136

Query: 134 PKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLP--PHLSL 191
             +FQ Y+  DR     L+ R   AG+  + +TVD P    RE + R+ +  P  P+ +L
Sbjct: 137 -AWFQAYLSADRDADAALLDRVAAAGYETLVVTVDVPVAANREHNKRSGYTAPLRPNAAL 195

Query: 192 ANFA------------------DMKDFAQVKGGAGASGLASYVASLID--ASLNWNDIAW 231
           A  A                   +  +  +  G GA   +S  A      A+ +W D+A 
Sbjct: 196 AWQALTHPRWLVGTLARTLLMGGVPRYRNLAAGNGARVFSSEAAHQFSRRAAFDWQDLAR 255

Query: 232 LKSITRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRG 291
           ++   R  ++LKG+++A D   A ++G DG+ +SNHG RQLD   A +  L E+  +  G
Sbjct: 256 IRQRWRGNLVLKGILSAADTVIAREHGVDGVIVSNHGGRQLDSAIAPLTVLPEIVDAAAG 315

Query: 292 RIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAM 351
            + V IDSG+RRGTD++KALALGA  V IGRP  +  AV G  GV  L +LL+DE    M
Sbjct: 316 -LTVMIDSGIRRGTDILKALALGAQMVFIGRPFNFAAAVGGAPGVAHLAALLRDEIARDM 374

Query: 352 QLCG 355
            L G
Sbjct: 375 ALLG 378

ref|ZP_00293245.1| COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Thermobifida fusca]
(402 aa)

Score: 182 bits (463), Expect: 9.9231e-45
Length: 388, Idn/Pos/Gap = 133/207/32 (34%/53%/8%)

Query:  11 TQPL-NLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVS-RV  68
           + PL ++AE    AK RLP  VY    +G +   TL DN +AF  +   PR+  D+  + 
Sbjct:   5 SAPLESVAEAQRRAKKRLPTAVYASLIAGTEKGLTLHDNIQAFDEIGLIPRIAADLPPQR  64

Query:  69 DITKQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAA 128
           +++  VMG ++SFP++V+P   Q +  P GE+A ARA A  GT +GLSS+A+   EDVAA
Sbjct:  65 EMSTTVMGQEISFPVIVSPAGAQAV-DPGGEVAVARAAAAAGTAIGLSSFASMPFEDVAA 123

Query: 129 HVPGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPH 188
             P    FFQLY    R      V  A +AG + + LT+D     RR+        +P  
Sbjct: 124 ANP--KAFFQLYWVGTRDDIAERVEHARQAGAKGLILTLDWSFASRRDW---GSPTIPER 178

Query: 189 LSLANFADMKDFAQVKGGAG-------------------ASGLASYVASLIDASLN---- 225
           ++L+   +       + G                     A G  ++  + ++ +      
Sbjct: 179 VTLSTLVEFLPMGLSRPGWALRFLLGGIPDLKAPNLRTRAKGTPTFKQAYVEWTQTPLPT 238

Query: 226 WNDIAWLKSITRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEV 285
           W+D+ WL+ +     ++KGV   +DA+RA+  GA  I +SNHG   LDG+ A++  L  V
Sbjct: 239 WDDVRWLRELWGGEFMVKGVFYPDDARRAVDCGATAISVSNHGGNNLDGIPASLRALPAV 298

Query: 286 AQSVRGRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKD 345
            ++V  ++ V +D G+RRG+DVVKALA+GA AVL+GR  +WGLA  GEEGV ++L +L+ 
Sbjct: 299 VEAVGDQVEVLMDGGIRRGSDVVKALAMGAKAVLVGRVWLWGLAAGGEEGVRQVLEILRS 358

Query: 346 EFKLAMQLCGCQKVSDIR-RDLVVRDAF 372
               A+   G + + ++   DLV+ + F
Sbjct: 359 GIDEALIGLGHKSIRELSPNDLVIPEGF 386

emb|CAB61541.1| putative oxidoreductase [Streptomyces coelicolor A3(2)]
ref|NP_625066.1| putative oxidoreductase [Streptomyces coelicolor A3(2)]
(389 aa)

Score: 182 bits (463), Expect: 1.26396e-44
Length: 349, Idn/Pos/Gap = 137/187/7 (39%/53%/2%)

Query:  13 PLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITK  72
           P +L       + RL    +GY A  A D  T R N  A  R R  PR+L DV   D+  
Sbjct:  25 PTDLTRLEELTERRLGPGPFGYVAGSAGDGSTARANRAALARRRIVPRMLRDVHERDLRV  84

Query:  73 QVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPG 132
           +V+G  L  PL +AP  +  + HPE E A ARA A  G    LSS ++T +E+VA  +  
Sbjct:  85 EVLGRSLPAPLALAPVGVLSIMHPEAEPAAARAAAAQGVPYILSSASSTPMEEVAEAMGD 144

Query: 133 LPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLA 192
             ++FQLY  KDR +    + RA  AG+ A+ +T+DTP L  R  D+ +Q  LP    + 
Sbjct: 145 AERWFQLYWPKDREVARSFLDRARAAGYTALFVTLDTPLLSWRPRDL-DQAYLPFLHGVG 203

Query: 193 NFADMKDFAQVKGGAGA------SGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVV 246
                 D A   G A        + +  +V    D + +W D+A+L+     PI+LKGV+
Sbjct: 204 TANYFSDPAFRAGLAKPVHEDPNAAVMHFVGMFSDPAKSWPDLAFLRENWDGPIVLKGVL 263

Query: 247 TAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTD 306
             +DA+ A   G DG+ +SNHG RQ+ G  A  D L  VA++V  R+ V  DSGVR G D
Sbjct: 264 HPDDARLAADAGMDGVVVSNHGGRQVAGSVAAADALPRVAEAVGDRLTVLFDSGVRTGDD 323

Query: 307 VVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCG 355
           V KALALGA AVL+GRP V+GL +DG  GV  ++  L  E  L + L G
Sbjct: 324 VFKALALGARAVLLGRPYVYGLGLDGRPGVEHVIRCLLAELDLTLALSG 372

gb|AAH44114.1| LOC398510 protein [Xenopus laevis]
(251 aa)

Score: 181 bits (460), Expect: 2.30481e-44
Length: 179, Idn/Pos/Gap = 86/123/0 (48%/68%/0%)

Query:  16 LAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVM  75
           LA++  +AK  LP   + YYA+GAD+  T  DN +AFRR+R RPR+L DVS +D    V+
Sbjct:  39 LADFEAYAKENLPKATWEYYAAGADECYTRDDNLQAFRRIRLRPRMLRDVSVMDTKTTVL  98

Query:  76 GIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPK 135
           G ++S P+ +APTA   +A  +GE++TARA   +  +   S++AT S+E+++   P   +
Sbjct:  99 GEEISCPIAIAPTAFHCLAWSDGEMSTARAAEALKLLYVASTYATCSVEEISQAAPEGLR 158

Query: 136 FFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANF 194
           +FQLYVY+DR ++ERL+RR E  GF+A+ LTVD P  G+R  DIRN FQLPPHL + NF
Sbjct: 159 WFQLYVYRDRKLSERLIRRVEALGFKALVLTVDVPYTGKRRTDIRNNFQLPPHLKVKNF 217

emb|CAE41589.1| putative L-lactate dehydrogenase [Bordetella pertussis Tohama I]
ref|NP_880060.1| putative L-lactate dehydrogenase [Bordetella pertussis Tohama I]
(393 aa)

Score: 181 bits (459), Expect: 3.24493e-44
Length: 361, Idn/Pos/Gap = 126/182/25 (34%/50%/6%)

Query:  31 VYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGIDLSFPLMVAPTAM  90
           ++GY A  A+D Q   DN  AF    F PRVL+DVS      ++ G + + P  VAP  +
Sbjct:  35 IFGYVAGAAEDNQAHDDNRRAFAEYGFLPRVLVDVSARHTRTELFGQEWAAPFGVAPMGI  94

Query:  91 QRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFFQLYVYKDRAITER 150
             ++   G++  ARA    G    +S  +   LE+VA   PG   +FQ Y+  D    + 
Sbjct:  95 SALSAYRGDIVLARAARAAGIPAIMSGSSLIPLEEVARQAPG--TWFQAYLPGDPGRIDA 152

Query: 151 LVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLP--PHLSLA------------NFA- 195
           LV R  RAG+  + LTVD P    RE ++R  F  P  P L LA             F  
Sbjct: 153 LVERVARAGYWTLVLTVDIPVSANRENNVRTGFSTPLKPGLRLAWDGLSRPRWLAGTFLR 212

Query: 196 -----DMKDFAQVKGGAGASGLASYVASLIDAS--LNWNDIAWLKSITRLPILLKGVVTA 248
                 M  F       GA  L++ V     A   L+W+ +  ++   R  +++KG++  
Sbjct: 213 TLLAHGMPHFENSFATRGAPILSANVLRDFSARDHLDWSHVQRIRRSWRGELVIKGIMHP 272

Query: 249 EDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVV 308
            DA  A  +GADGI +SNHG RQLDG  A +  L ++A++  G + V +DSG+RRG DV+
Sbjct: 273 RDAALARAHGADGIIVSNHGGRQLDGACAPLRVLPDIAEAA-GAMAVMMDSGIRRGGDVL 331

Query: 309 KALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLVV 368
           KALALGA  V +GRP  +  AV GE GV   + LL++E    M + G  + + +   L+ 
Sbjct: 332 KALALGARFVFLGRPFNYAAAVGGEAGVAHAIGLLREEIDRNMAMLGVTRCTAMAPGLLR 391

Query: 369 R 369
           R
Sbjct: 392 R 392

gb|AAV93913.1| FMN-dependent alpha-hydroxy acid dehydrogenase family protein [Silicibacter pomeroyi DSS-3]
ref|YP_165858.1| FMN-dependent alpha-hydroxy acid dehydrogenase family protein [Silicibacter pomeroyi DSS-3]
(371 aa)

Score: 179 bits (455), Expect: 8.6855e-44
Length: 352, Idn/Pos/Gap = 116/186/11 (32%/52%/3%)

Query:  22 FAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGIDLSF  81
            A+ RLP MV+ Y    A +E        A + +R  PRVL +VSR ++  Q+       
Sbjct:  16 LARKRLPWMVFDYVDGAAGEEHGAMLARRAIQDIRLTPRVLRNVSRRELRVQLFDKLAVR  75

Query:  82 PLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFFQLYV 141
           P  ++P  M  ++ P+ +L  AR  AR     G+S+ A+T +E +     G+  +FQLY 
Sbjct:  76 PFGISPMGMCNLSAPDADLMLARLAARDRVPHGVSTVASTDMETLLKASGGM-AWFQLYF 134

Query: 142 YKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANFADMKDFA 201
             D + T +LV RA  AG+  + LTVD P++GRR  ++R+ F++P  +    F D     
Sbjct: 135 SGDGSGTMKLVERARAAGYGTLVLTVDVPEVGRRPRELRHGFKMPFRIGPRQFVDFALHP 194

Query: 202 Q------VKGGAGASGL--ASYVASLID--ASLNWNDIAWLKSITRLPILLKGVVTAEDA 251
           +      ++G    +     +YV    +  A+ +W     L++     +++KGV+   DA
Sbjct: 195 RWSLSTLIRGRPQMANFDGRNYVFDRTESRAAADWTTFETLRATWPGKLVVKGVLHPGDA 254

Query: 252 QRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKAL 311
            R    GAD I +S+HG RQLD     I+ L  + Q+V    P+F DSG+R G DVVKA 
Sbjct: 255 LRLKALGADAIQVSSHGCRQLDAAPPAIEALAAIRQAVGPSYPLFYDSGIRSGEDVVKAY 314

Query: 312 ALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIR 363
           A+GAD V +GRP+++ +A  GE G+++L  +L  E  L +   G  +++ +R
Sbjct: 315 AMGADFVFLGRPLLYAMAAGGEAGLHQLWEVLAQEVSLTLAQLGLTEMAALR 366

ref|ZP_00055191.1| COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Magnetospirillum magnetotacticum MS-1]
(376 aa)

Score: 179 bits (455), Expect: 9.2079e-44
Length: 318, Idn/Pos/Gap = 114/165/20 (35%/51%/6%)

Query:  23 AKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGIDLSFP  82
           A+ R+P   +G+   G+ +E  LR N +    +   P+     ++ D T  + G D   P
Sbjct:  14 ARWRIPGFAFGFLDGGSGEEDGLRRNRDRLEAVILAPKACTG-AKPDTTATLFGRDYRLP  72

Query:  83 LMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFFQLYVY 142
              AP  M  +  P  +L  AR  AR+G  +  S+ ATT+LED+A    G   +FQLYV 
Sbjct:  73 FGAAPVGMGNLLWPGADLMVARQAARLGFPVVASTVATTALEDIAKAADG-NAWFQLYVS 131

Query: 143 KDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLP--------PHLSLANF 194
           ++  I   L+ RA  AG R + +TVD P  G R  D+RN+F LP          L++A F
Sbjct: 132 REERINRDLLARAWAAGIRELVVTVDVPVAGDRRRDLRNRFVLPFKPGARFVAQLAMAPF 191

Query: 195 ADMK----------DFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKG 244
             +           + A+  G      LA +++S I   L W+D+  L+   +  +L+KG
Sbjct: 192 WALSTLKHGSPGFPNLARYVGEVDGKTLAGFISSQIKDDLTWDDLKSLRDQWQGRMLVKG 251

Query: 245 VVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRG 304
           ++TA DA+ AL  GADGIW+SNHG RQLD   A ID L  +  ++     V +D G+R G
Sbjct: 252 IMTASDAKTALGLGADGIWVSNHGGRQLDSAPAAIDSLSAIRAALGPDPVVVMDGGIRSG 311

Query: 305 TDVVKALALGADAVLIGR 322
            DVV+A A GAD V  GR
Sbjct: 312 EDVVRAGATGADFVFCGR 329

ref|YP_111566.1| putative L(+)-mandelate dehydrogenase [Burkholderia pseudomallei K96243]
emb|CAH39033.1| putative L(+)-mandelate dehydrogenase [Burkholderia pseudomallei K96243]
ref|YP_106149.1| dehydrogenase, FMN-dependent family [Burkholderia mallei ATCC 23344]
gb|AAU45818.1| dehydrogenase, FMN-dependent family [Burkholderia mallei ATCC 23344]
(407 aa)

Score: 179 bits (453), Expect: 1.6651e-43
Length: 378, Idn/Pos/Gap = 129/189/24 (34%/50%/6%)

Query:  14 LNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQ  73
           L+L ++   A+  LP  ++GY    A+D +T  DN  AF    F  RVL DVS+     +
Sbjct:  30 LSLHDFEARARRALPRPIFGYVGGAAEDNRTRDDNRAAFDEYGFVTRVLRDVSQRQQGVE  89

Query:  74 VMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGL 133
           + G   + P  +AP  +  ++   G++  ARA    G    +S  +   LEDVAA  P  
Sbjct:  90 LFGRRYASPFGIAPMGINALSTYRGDIVLARAAQHAGIASIMSGSSLIPLEDVAAAAPD- 148

Query: 134 PKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLP------- 186
             +FQ Y+  D      LV R  RAG+R + +TVD P    RE ++R+ F  P       
Sbjct: 149 -TWFQAYLPGDAGRIRALVERVARAGYRTLVVTVDIPVSANRENNVRSGFSTPLRPSPRL 207

Query: 187 -------PHLSLANFA------DMKDFAQVKGGAGASGLASYVASLIDAS--LNWNDIAW 231
                  P   L  FA       M  F       GA  L++ V     A   L+W  +  
Sbjct: 208 FWDGLTRPRWLLGTFARTLLAHGMPHFENSFATRGAPILSANVLRDFSARDHLSWAHVRQ 267

Query: 232 LKSITRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRG 291
           ++      +++KGV++ EDA+ A + GADGI +SNHG RQLDG  + +  L +V Q+V  
Sbjct: 268 IREQWAGELVIKGVLSVEDARIAREAGADGIILSNHGGRQLDGAVSPMRILRDVVQAVGN 327

Query: 292 RIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAM 351
             PV IDSG RRG+DV+KA+ALGA  V +GRP  +  AV GE GV   + LL++E    +
Sbjct: 328 GYPVMIDSGFRRGSDVLKAVALGARMVFVGRPFNYAAAVAGEAGVAHAIRLLREEVDRNL 387

Query: 352 QLCGCQKVSDIRRDLVVR 369
            + G      +  D+++R
Sbjct: 388 AMLGANGCDALTPDMLIR 405

gb|AAP69813.1| putative glycolate oxidase [Vitis vinifera]
(156 aa)

Score: 178 bits (452), Expect: 1.95114e-43
Length: 148, Idn/Pos/Gap = 88/115/0 (59%/77%/0%)

Query: 228 DIAWLKSITRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQ 287
           D+ WL++IT+LPIL+KGV+TAEDA+ A+  GA GI +SNHGARQLD V ATI  LEEV +
Sbjct:   2 DVKWLQTITKLPILVKGVLTAEDARIAVNVGAAGIIVSNHGARQLDYVPATIMALEEVVK  61

Query: 288 SVRGRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEF 347
           + +GRIPVF+D GVRRGTDV KALALGA  + IGRP+V+ LA DGE GV + L +L+DEF
Sbjct:  62 ATQGRIPVFLDGGVRRGTDVFKALALGASGIFIGRPVVYSLAADGEAGVRKALQMLRDEF 121

Query: 348 KLAMQLCGCQKVSDIRRDLVVRDAFAPY 375
           +L M L GC+ + +I R+ ++ D  AP+
Sbjct: 122 ELTMALSGCRSLKEISRNHIMTDWDAPH 149

ref|NP_419967.1| L-lactate dehydrogenase [Caulobacter crescentus CB15]
gb|AAK23135.1| L-lactate dehydrogenase [Caulobacter crescentus CB15]
pir||C87392 L-lactate dehydrogenase [imported] - Caulobacter crescentus
(383 aa)

Score: 175 bits (444), Expect: 1.58425e-42
Length: 364, Idn/Pos/Gap = 132/190/20 (36%/52%/5%)

Query:  23 AKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGIDLSFP  82
           A+ RLP  ++ Y   GA  E+T+  N +    +  R RVL+DVS VD +  + G+  + P
Sbjct:  13 ARRRLPRFLFDYIDGGAYAERTMARNIDDLADIALRQRVLMDVSVVDPSTTLFGVRQALP  72

Query:  83 LMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFFQLYVY 142
           + +AP  +  M    GE   ARA A  G    LS+ +   +++V A     P +FQLYV 
Sbjct:  73 VALAPVGLTGMYARRGECQAARAAAAKGVPFCLSTVSVCDVDEVRA-ASATPFWFQLYVL 131

Query: 143 KDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLS--LANFADMKDF 200
           +DR     L+ RA  AG   +  TVD P  G R  D  +    P   +  L   A    +
Sbjct: 132 RDRGFMRDLLARASAAGATTLVFTVDMPVPGARYRDAHSGMSGPNAAARRLVQAALKPAW 191

Query: 201 AQVKGGAG--------------ASGLASY---VASLIDASLNWNDIAWLKSITRLPILLK 243
           A   G  G              ASGL  +   +A+  D S+ W+D+ W++   + P+++K
Sbjct: 192 AWDVGVMGHPHRLGNVAPALGKASGLQDFMGWLAANFDPSIQWSDLKWIRDAWKGPLVIK 251

Query: 244 GVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRR 303
           GV+  EDA+ A   GADG+ +SNHG RQLDGV ++   L  +A +V  R+ V  D GVR 
Sbjct: 252 GVLDPEDAKAAADIGADGVVVSNHGGRQLDGVLSSARALPAIADAVGDRLTVLADGGVRS 311

Query: 304 GTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIR 363
           G DVV+ LALGA  VLIGR   + LA  GE GV +LL L+  E ++AM L G + V+ I 
Sbjct: 312 GLDVVRMLALGARGVLIGRAYAYALAARGEAGVTQLLDLIDKEMRVAMALTGVRDVASIN 371

Query: 364 RDLV 367
             ++
Sbjct: 372 ETIL 375

ref|ZP_00335964.1| COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Silicibacter sp. TM1040]
(390 aa)

Score: 171 bits (433), Expect: 3.11505e-41
Length: 365, Idn/Pos/Gap = 119/178/27 (32%/48%/7%)

Query:  23 AKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGIDLSFP  82
           A+ RLP  V+ Y  S    E T   N     R+   P +L     VD+   + G  L  P
Sbjct:  21 ARTRLPRFVWEYLDSATGREATQARNRLCLDRIGLMPAILGGPQEVDLGTTLFGTPLPRP  80

Query:  83 LMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFFQLYVY 142
             +AP  M  +  P+ E   AR  A+     GLS+ A+ S ED+A H+ G   +FQ+Y  
Sbjct:  81 FGIAPVGMSGLIWPDAEGHLARHAAQTNIPYGLSTVASQSPEDLAPHL-GAQGWFQMYPP 139

Query: 143 KDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLS---LANFADMKD 199
           KD  I + ++ RA  AGF+ + LTVD P   RRE   R+    PP L+   LA  A    
Sbjct: 140 KDEGIRKDMLERARAAGFKVLVLTVDVPVASRRERQTRSGLTQPPRLTPRLLAQVAIRPA 199

Query: 200 FA---------------------QVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRL 238
           +A                      ++G A A    +++  L+  + +W  + WL+     
Sbjct: 200 WALGMARQHRGEGGMPHMRTLDKYIEGAASALSSTAHIGYLLRTAPDWAYLEWLRDHWEG 259

Query: 239 PILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFID 298
           P+++KGV+ A DA R    GAD IWISNH  RQ D   A I+ LE++  +    +P+ +D
Sbjct: 260 PLVVKGVLDACDAPRLEAAGADAIWISNHAGRQFDAAPAPIEVLEDIRAAT--TLPLILD 317

Query: 299 SGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQK 358
           SG+  G D+++ALALGAD V++GR   + LA  G  G   L  +L  +    M   G + 
Sbjct: 318 SGIEGGLDILRALALGADFVMLGRAWHYALAALGAAGPAHLHDILSKDLTANMGQLGIRT 377

Query: 359 VSDIR 363
           ++++R
Sbjct: 378 LAEVR 382

ref|ZP_00196129.2| COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Mesorhizobium sp. BNC1]
(374 aa)

Score: 171 bits (433), Expect: 3.61985e-41
Length: 355, Idn/Pos/Gap = 114/179/25 (32%/50%/7%)

Query:  23 AKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVS-RVDITKQVMGIDLSF  81
           A+ R+P   + +    A  E  L  N  AF     RPR L++    +   ++ +G + S 
Sbjct:  19 ARRRMPRFAFDFIDGAAGSEAGLARNRAAFEAELLRPRALVNTDGDLKTGRRFLGQEWSV  78

Query:  82 PLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFFQLYV 141
           P  ++P  +  +A P  +L  A A  R G     S+ AT SLED+      +  +FQLYV
Sbjct:  79 PFGISPIGLAGIAWPGIDLVLAGAAERNGAPYIASTPATASLEDLK-RTAAVSAWFQLYV 137

Query: 142 YKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLP--------------P 187
            + + I + L+ RA  AG+  + +TVD P+ G+R  D+RN F LP              P
Sbjct: 138 GRSQEIVDDLIDRAAAAGYEVLVVTVDVPRPGKRRRDLRNGFALPLKIGPRMIADLMTHP 197

Query: 188 HLSL-------ANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPI 240
             SL         FA+++ +A    GAGA  LA  +A      L+W  +A L+   +  +
Sbjct: 198 KWSLEVLRKGAPRFANLERYA--PPGAGARSLAELMAGQSSGRLDWTLLAQLRERWQGRL 255

Query: 241 LLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSG 300
           ++KG++  EDA RA + G D + +SNHG RQLD   AT+  L+++ ++V     + +D G
Sbjct: 256 VVKGIMAPEDAMRAREEGVDAVIVSNHGGRQLDSAPATLHALKQIREAVGPDYSLAVDGG 315

Query: 301 VRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCG 355
           +R G D++K+L  GAD   +GRP ++ +A  G  G   L  +L+ E   AM   G
Sbjct: 316 IRTGEDILKSLFAGADFTFLGRPFLYAVAARGTNGANDLFDMLRAELVNAMAQVG 370

ref|ZP_00385571.1| COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Lactobacillus casei ATCC 334]
(264 aa)

Score: 170 bits (431), Expect: 5.09635e-41
Length: 274, Idn/Pos/Gap = 107/161/10 (39%/58%/3%)

Query: 100 LATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFFQLYVYKDRAITERLVRRAERAG 159
           +  A+     G +M  S++A+ ++ + AA   G P  FQLY+ KD +  + L+ +A++AG
Sbjct:   1 MGLAKGAKEAGIMMSQSTFASKTIAETAAVSDGAPYMFQLYMPKDWSYCQYLLDQAKQAG  60

Query: 160 FRAIALTVDTPQLGRREADIRNQFQLPPHLSLANFADMKDFAQVKGGAGASGLASYVASL 219
             AI LT D+   G RE D+ N + L   L     A+++ +   + G GA GL       
Sbjct:  61 ALAIILTADSTLGGYREKDVMNHYHLKGRL-----ANLEGYNTGQQGVGAGGLFKESMQK 115

Query: 220 IDASLNWNDIAWLKSITRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATI 279
           +D +     I  L S + LPI++KG+   +DA  A+  GA GI++SNHG RQLDG    I
Sbjct: 116 LDLA----TIDKLASYSGLPIIVKGIQHPDDAVAAITAGAAGIYVSNHGGRQLDGAPGAI 171

Query: 280 DCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRL 339
           + L  +A +V  R+P+  D GV+RGT V+KALALGAD V IGRP  +GLA+ G EGV  +
Sbjct: 172 EALPAIAAAVDHRVPIIFDGGVQRGTHVLKALALGADLVGIGRPFSYGLALGGWEGVKAV 231

Query: 340 LSLLKDEFKLAMQLCGCQKVSDIRRDLVVRDAFA 373
              +K E  +AMQL GCQ ++D+++ + ++  FA
Sbjct: 232 ADHMKMEINIAMQLTGCQTMADVKQ-MQIKTTFA 264

gb|EAA68157.1| hypothetical protein FG01531.1 [Gibberella zeae PH-1]
ref|XP_381707.1| hypothetical protein FG01531.1 [Gibberella zeae PH-1]
(383 aa)

Score: 170 bits (431), Expect: 6.12322e-41
Length: 344, Idn/Pos/Gap = 112/179/38 (32%/52%/11%)

Query:  12 QPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDIT  71
           Q + L ++   A+  LP   Y YY +GA  E + R+N E F+R RF+PR ++D++ V+ T
Sbjct:  45 QMIGLPDFEWAAQNYLPIENYTYYRNGAAGEWSYRNNLEVFQRYRFKPRTMVDITNVENT 104

Query:  72 --KQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVA-A 128
               ++G + S P  ++P A    AHP+ E    +  A    +   + +A+ ++E++A A
Sbjct: 105 LPTTILGHNFSAPFFISPCAKGGNAHPDAEKNFVKGAAAGDILYMPALYASLTIEEIAKA 164

Query: 129 HVPGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPH 188
              G   F QLY+  +   T+ L+ R+E+AG  AI  TVD+   G R    R        
Sbjct: 165 KAEGQVVFQQLYLSSNDTETQELLDRSEKAGAAAIIFTVDSAADGNRHRAARF------- 217

Query: 189 LSLANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTA 248
                           G   A    SY+         W+    L+ +T+LP+++KG+ +A
Sbjct: 218 ----------------GVGSADSDYSYIT--------WDYYKKLQKMTKLPVVIKGIGSA 253

Query: 249 EDAQRALQYGADGIWISNHGARQLDGVTATIDC---LEEVAQSVRGRIPVFIDSGVRRGT 305
            DA+ A+Q+GA  I +SNHG RQLDG  + ++    + E A  V  +I V+ D GVR G 
Sbjct: 254 ADAKLAVQHGAPAIILSNHGGRQLDGSPSGLEVALEIHEEAPEVFKKIEVYADGGVRYGA 313

Query: 306 DVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKL 349
           DV+K L+LG  AV +GRP ++   V G +GV +++ +LK E  +
Sbjct: 314 DVLKLLSLGVKAVGLGRPFMYA-NVFGVDGVKKVIDILKHEIAI 356

ref|XP_323892.1| hypothetical protein [Neurospora crassa]
gb|EAA26743.1| hypothetical protein [Neurospora crassa]
(459 aa)

Score: 168 bits (426), Expect: 2.44627e-40
Length: 398, Idn/Pos/Gap = 125/185/54 (31%/46%/13%)

Query:  22 FAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMG--IDL  79
            A  +L    + Y +S A    T   N +AF R +  PR LID +       +     ++
Sbjct:  45 LASRKLSQNGWLYASSNAGLSHTHLANRQAFFRHKLVPRQLIDTNERSTRISLFDGKWEV 104

Query:  80 SFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDV------------- 126
           S P  +AP  + ++ H +GELA A+A   +G V  LS+  +  +EDV             
Sbjct: 105 SAPFGIAPVGINKIYHDQGELAVAKAAGELGLVYSLSTAGSFPIEDVGEANEEGRANRFK 164

Query: 127 ------------------AAHVPGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVD 168
                             +  VP  P+FFQLY+  D  +T  L++RA  +GF+A  LT D
Sbjct: 165 ANENLDVDGEGSEGGNENSKKVPEAPRFFQLYMPHDDKLTLSLLKRAHESGFQACILTTD 224

Query: 169 TPQLGRREADIRNQFQ-----LPPHLSLANFADMKDFAQVKGGAGASGLASYVASL-IDA 222
           T QLG R  D+          +   L   +    K  A+   G      A   AS+ ID 
Sbjct: 225 TSQLGWRHDDVATSNYAFYRGIGGELGFTDPVFQKRMAE--AGVDPQKDAVKAASMWIDT 282

Query: 223 -----SLNWNDIAWLKSITR------LPILLKGVVTAEDAQRALQYGADGIWISNHGARQ 271
                + +W    W +   +         L+KG+ +  DA++A   G +G+ +SNH  RQ
Sbjct: 283 IWHGRAWSWEKAVWAREKWQEIAGKDKLFLIKGIQSVNDAKKAADLGFEGVVVSNHAGRQ 342

Query: 272 LDGVTATIDCLEEVAQSVRGR--IPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLA 329
           +DG   ++D LE + ++V  R    V  DSGVR   DV+KALALGA  V IGR  +WGLA
Sbjct: 343 VDGAVGSLDALESIVKAVGERRGFTVMFDSGVRGAADVMKALALGAKFVFIGRLWIWGLA 402

Query: 330 VDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLV 367
           + GEEGV  +L  L  +F + M + G + V +I   L+
Sbjct: 403 IMGEEGVRHVLRSLLADFDILMNVMGVRSVDEIDASLL 440

gb|AAV94468.1| FMN-dependent alpha-hydroxy acid dehydrogenase family protein [Silicibacter pomeroyi DSS-3]
ref|YP_166419.1| FMN-dependent alpha-hydroxy acid dehydrogenase family protein [Silicibacter pomeroyi DSS-3]
(371 aa)

Score: 165 bits (417), Expect: 2.40649e-39
Length: 358, Idn/Pos/Gap = 118/178/21 (32%/49%/5%)

Query:  23 AKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGIDLSFP  82
           A+ RLP  V+ Y  SG   E T   N  +  R+ F P VL      D+T  ++G   + P
Sbjct:   7 ARRRLPRFVWEYLDSGTGVEATKARNRASLDRVGFLPSVLHGPLEHDLTTTLLGTTYALP  66

Query:  83 LMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFFQLYVY 142
             VAP  M  +  P+ E   ARA A       LS+ A+ S ED+A H+ G   +FQLY  
Sbjct:  67 FGVAPVGMSGLIWPDAEGHLARAAAAANIPYCLSTVASQSPEDLAPHI-GPQAWFQLYPP 125

Query: 143 KDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLS---LANFA---- 195
           K+  I   LV RA +AGF+ + LTVD P   RRE  +R+    PP L+   LA  A    
Sbjct: 126 KNPDIRRDLVERARQAGFKTLVLTVDVPVASRRERQVRSGLTQPPTLTPRLLAQVAMRPA 185

Query: 196 -----------DMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKG 244
                       M+   +   G       +++  L+  S   + +AWL+   + P ++KG
Sbjct: 186 WAMGMARRGMPHMRTLDKYSQGLTNLPPTAHIGYLLRTSPTEDYVAWLRDAWQGPFVVKG 245

Query: 245 VVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRG 304
           V+  ED +R  + G D +W+SNH  RQ DG     + L  +  +   R+P+  DSGV  G
Sbjct: 246 VLRPEDGERMERLGVDALWVSNHAGRQFDGAPGAAEMLPHIRAAT--RLPLIFDSGVESG 303

Query: 305 TDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDI 362
            D+++ALALGAD V++GR   +GLA  G  G    + +L+ + +  +   G  +++D+
Sbjct: 304 LDILRALALGADFVMLGRAFHFGLAALGPRGAAHAIDILQKDIESNLGQLGAARLTDL 361

gb|EAA61701.1| hypothetical protein AN7055.2 [Aspergillus nidulans FGSC A4]
ref|XP_411192.1| hypothetical protein AN7055.2 [Aspergillus nidulans FGSC A4]
(387 aa)

Score: 160 bits (406), Expect: 4.28095e-38
Length: 344, Idn/Pos/Gap = 111/174/40 (32%/50%/11%)

Query:  14 LNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDIT--  71
           L L ++   AK  L A  Y YY +GA  E + R+N E + R RFRPRV++D+++++ T  
Sbjct:  49 LGLPDFEWAAKRYLNASSYTYYRNGAAGEWSYRNNLEVYGRFRFRPRVMVDITQIEKTLP 108

Query:  72 KQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVP 131
             ++G + S P  ++P A   +AHP+ E    +A      +   +  AT S++++AA  P
Sbjct: 109 TTILGHNFSAPFYISPCASAGLAHPDAEANFVKAAYEENILYIPALLATLSMDEIAAAKP 168

Query: 132 ---GLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPH 188
                  F Q Y+  +   T+++   AER G +AI  T+D+P  G R    R        
Sbjct: 169 EDGSQVLFQQAYLNSNDTATQQVFDDAERLGAKAIVWTIDSPADGNRHRANRY------- 221

Query: 189 LSLANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTA 248
                            G G+S  + Y  S       W   A L+++T LPI+LKG+   
Sbjct: 222 -----------------GVGSSD-SDYTLS------TWEFYAKLQNMTTLPIVLKGIQHV 257

Query: 249 EDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQS---VRGRIPVFIDSGVRRGT 305
           ED + A+++G   I +SNHG RQLD   ++++   EV Q    +  +I ++ D G+R G 
Sbjct: 258 EDVKLAIKHGVPAIILSNHGGRQLDSSPSSLEVALEVYQEDPDLFNQIEIYADGGIRYGA 317

Query: 306 DVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKL 349
           DV+K L+LG  AV +GR  ++  A  G EGV   + LLK E  +
Sbjct: 318 DVLKLLSLGVKAVGLGRSFMYANAY-GAEGVRHAIQLLKHEIAI 360

gb|EAA48032.1| hypothetical protein MG09162.4 [Magnaporthe grisea 70-15]
ref|XP_364317.1| hypothetical protein MG09162.4 [Magnaporthe grisea 70-15]
(383 aa)

Score: 152 bits (384), Expect: 1.81419e-35
Length: 338, Idn/Pos/Gap = 100/165/38 (29%/48%/11%)

Query:  16 LAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRV--DITKQ  73
           L ++   A+  LP + Y YY +GA  E + R+N E + R + RP+ ++D++ +   +   
Sbjct:  49 LHDFEWAARRYLPKVNYTYYRNGAGGEWSYRNNLEVYNRYKLRPKTMVDITNIAESMPTT 108

Query:  74 VMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAA-HVPG 132
           ++G + S P  + P A     HP+ EL   +       +   SS++T  +E +AA   P 
Sbjct: 109 ILGHNFSAPFFICPCARAGYGHPDAELNLVQGAGAGKILYIPSSFSTLPIEQIAAKRAPD 168

Query: 133 LPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLA 192
              F Q+Y   +    + L  RAE+AG +A+   +D P    R+                
Sbjct: 169 QILFSQVYTNDNDTANQILFDRAEKAGSKALVWAIDAPGSPSRQR--------------- 213

Query: 193 NFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQ 252
                         A   G+ S  A  I  +  W  +   +++T+LP +LKG+ T EDA+
Sbjct: 214 --------------AARYGVGSANAVFITNT--WEVLDKFRTMTKLPFILKGIQTVEDAK 257

Query: 253 RALQYGADGIWISNHGARQLDGVTATIDCLEEV---AQSVRGRIPVFIDSGVRRGTDVVK 309
            A+Q+    I +SNHG R LDG  ++++   E+   A  +  +I V  D GVR GTD ++
Sbjct: 258 LAVQHKVPAIILSNHGGRNLDGSPSSLEIALEIHREAPEIFEQIEVLADGGVRYGTDALR 317

Query: 310 ALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEF 347
            LALG  AV IGRP+++   V G +GV R + + ++E 
Sbjct: 318 LLALGVKAVGIGRPMMYS-NVFGVDGVKRAVEIFRNEL 354

ref|ZP_00387640.1| COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365]
(203 aa)

Score: 143 bits (361), Expect: 7.56098e-33
Length: 126, Idn/Pos/Gap = 67/91/0 (53%/72%/0%)

Query: 238 LPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFI 297
           LP+++KGV  AED + AL  GADG++++NHG R++DG  ATID L EV ++V GR PV  
Sbjct:  31 LPVIVKGVNCAEDVEVALTAGADGVYVTNHGGREIDGAPATIDVLPEVVEAVNGRCPVIF  90

Query: 298 DSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQ 357
           D GVRRG+ V KALALGAD V I RP ++GLA+ G  GV  +++ L DE K+ MQL GC+
Sbjct:  91 DGGVRRGSHVFKALALGADLVGIDRPYLYGLALGGPHGVASIINELNDELKIDMQLTGCK 150

Query: 358 KVSDIR 363
            + D++
Sbjct: 151 TIEDVK 156

ref|XP_586447.1| PREDICTED: similar to hydroxyacid oxidase 2 (long chain), partial [Bos taurus]
(236 aa)

Score: 138 bits (348), Expect: 2.66609e-31
Length: 175, Idn/Pos/Gap = 66/107/0 (37%/61%/0%)

Query:   8 NPATQPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSR  67
           +P    + L ++   A+  L    + +   GADD  T  +N  AF+++R RPR L DVS+
Sbjct:  45 SPEMPLVCLTDFREHAREHLSKSTWDFIEGGADDCCTRDENMAAFKKIRLRPRYLKDVSK 104

Query:  68 VDITKQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVA 127
           VD+   + G ++S P+ +APT   R+A P+GE++TARA          S++A+ SLED+ 
Sbjct: 105 VDMRTTIQGAEISAPICIAPTGFHRLAWPDGEMSTARAAQAASICYITSTYASCSLEDIV 164

Query: 128 AHVPGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQ 182
           A  P   ++FQLYV+ +R I ++++++ E  GF+A+ +TVD P++G R  DI NQ
Sbjct: 165 AAAPRGLRWFQLYVHPNRQINKQMIQKVESLGFKALVITVDVPKVGNRRNDITNQ 219

ref|ZP_00277167.1| COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Burkholderia fungorum LB400]
(396 aa)

Score: 138 bits (347), Expect: 3.12409e-31
Length: 380, Idn/Pos/Gap = 118/179/25 (31%/47%/6%)

Query:  14 LNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQ  73
           L L ++   AK RLP  +Y Y    ++D  T R N   F    F PRVL+D+ R D    
Sbjct:  19 LCLNDFANVAKRRLPGAMYAYVHGWSEDGATHRRNLYGFETRAFVPRVLVDIERRDTRTT  78

Query:  74 VMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGL 133
           + G++ + P  +AP    R+A    +   AR  A  G    LS  + T LE V A   G 
Sbjct:  79 LFGVEYAAPFGIAPMGCSRLAAAHADELLAREAATAGLPFILSGASLTPLETVRA--AGS 136

Query: 134 PKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLP--PHLSL 191
             +FQ Y+  D A  + ++ R   AG+  + + VDT    + E   +  F+ P  P   L
Sbjct: 137 TSWFQAYIPGDFARIDPMLERVALAGYDTLVVNVDTAVHPQHEYADKRGFRSPFRPSAQL 196

Query: 192 ANFADMK------------------DFAQVKGGAGASGLASYVASLID--ASLNWNDIAW 231
           A  A  +                   F  +    G    +  +   I    +L+W  I  
Sbjct: 197 AWQALTRLPWCWRVLGESVLTRHPLRFENMDAIGGPPVFSRTLVRDIGRRGALSWAHIER 256

Query: 232 LKSITRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSV-R 290
           ++      ++LKGV++A+DA  A + G DGI +SNHG RQ+D     +D L+ +A  V R
Sbjct: 257 IRQRWPGRLVLKGVMSADDALLAQRAGIDGIIVSNHGGRQVDCALGALDALDAIAARVDR 316

Query: 291 GRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLA 350
            R+ +  D G+RRG+DV+KAL  GA  VL+GRP++   A     G+   LSLL+ E    
Sbjct: 317 DRLALIYDGGIRRGSDVLKALHGGAHFVLVGRPLLMAAAAADAIGIAYALSLLQREIGTN 376

Query: 351 MQLCGCQKVSDIRRDLVVRD 370
           M L G  ++ ++ +  + RD
Sbjct: 377 MGLLGINRIDEVAQLELRRD 396

ref|XP_513689.1| PREDICTED: similar to Hydroxyacid oxidase 2 (HAOX2) ((S)-2-hydroxy-acid oxidase, peroxisomal) (Long chain alpha-hydroxy acid oxidase) (Long-chain L-2-hydroxy acid oxidase) [Pan troglodytes]
(216 aa)

Score: 134 bits (336), Expect: 5.69839e-30
Length: 176, Idn/Pos/Gap = 67/102/0 (38%/57%/0%)

Query:   9 PATQPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRV  68
           P    + L ++   A+ +L    + +   GADD  T  DN  AF+R+R RPR L DVS V
Sbjct:  12 PEMSLVCLTDFQAHAREQLCKSTWDFIEGGADDSITRDDNIAAFKRIRLRPRYLRDVSEV  71

Query:  69 DITKQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAA 128
           D    + G ++S P+ +APT    +  P+GE++TARA    G     S++A+ SLED+  
Sbjct:  72 DTRTTIQGEEISAPICIAPTGFHCLVWPDGEMSTARAAQAAGICYITSTFASCSLEDIVI 131

Query: 129 HVPGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQ 184
             P   ++FQLYV+    + ++L++R E  GF+A+ +T+DTP  G R  DIRNQ +
Sbjct: 132 AAPEGLRWFQLYVHPVLQLNKQLIQRVESLGFKALVITLDTPVCGNRRHDIRNQLR 187

gb|AAV29906.1| NT02FT1139 [synthetic construct]
(196 aa)

Score: 132 bits (332), Expect: 1.83258e-29
Length: 207, Idn/Pos/Gap = 72/115/28 (34%/55%/13%)

Query: 179 IRNQFQLPPHLSLANFADM---------------KDFAQVKGG--AGASGLASYVASLID 221
           +RN   +PP   + +  ++               K F  + G    GA G+ S       
Sbjct:   1 MRNGLSIPPKFGIRDIINIAAKQSWVWGYLLSKYKQFGNLSGHIPTGAKGMKSVT-----  55

Query: 222 ASLNWNDIAWLKSITRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDC 281
                 D+ WL++I    +++KG++  + A+ A++ GADGI +SNH  RQLDGV  TI+ 
Sbjct:  56 ------DLEWLRNIWDGNLIIKGLLNTQGAENAVKVGADGIVVSNHRGRQLDGVLPTIEA 109

Query: 282 LEEVAQSVRGRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLS 341
           L  +A  V+G I + +DSG+R G D++KALALGAD  L+GRP ++GL+  G++GV ++  
Sbjct: 110 LPAIADKVKGDIKIILDSGIRSGQDIIKALALGADFTLVGRPFLYGLSAFGQKGVEKVYD 169

Query: 342 LLKDEFKLAMQLCGCQKVSDIRRDLVV 368
           +LK E    M L G   +++I  ++VV
Sbjct: 170 ILKKEIDNTMALAGISDLNNISTNVVV 196

dbj|BAB81584.1| probable glycolate oxidase [Clostridium perfringens str. 13]
ref|NP_562794.1| probable glycolate oxidase [Clostridium perfringens str. 13]
(340 aa)

Score: 127 bits (320), Expect: 4.01616e-28
Length: 174, Idn/Pos/Gap = 67/102/8 (38%/58%/4%)

Query: 204 KGGAGASGLASYVASLIDASLN--------WNDIAWLKSITRLPILLKGVVTAEDAQRAL 255
           K GA A G+    A LI  ++N          +I  L + T+LP +LKG++T ++A+ A+
Sbjct: 164 KAGAFAVGVDIDAAGLITLAMNGKPVEPKNLEEIKELVNSTKLPFILKGIMTPDEAELAV 223

Query: 256 QYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALALGA 315
           + G D I +SNHG R LD   A+ + L E+A  V+G++ + +D GVR G D++K +ALGA
Sbjct: 224 EAGVDAIVVSNHGGRVLDQTPASCEVLPEIAARVKGKVKILVDGGVRTGVDILKMIALGA 283

Query: 316 DAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLVVR 369
           D VLIGRP +      G +GV   ++ LK E K AM L GC  + +I   ++ +
Sbjct: 284 DCVLIGRPFITATFAHGAKGVEEYVNSLKGELKSAMVLTGCNSIENIDNRVIYK 337

emb|CAI23078.1| hydroxyacid oxidase 2 (long chain) [Homo sapiens]
(186 aa)

Score: 122 bits (307), Expect: 1.27057e-26
Length: 217, Idn/Pos/Gap = 74/110/36 (34%/50%/16%)

Query:  16 LAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVM  75
           L ++   A+ +L      +   GADD  T  DN  AF+R+R RPR L DVS VD    + 
Sbjct:   6 LTDFQAHAREQLSKSTRDFIEGGADDSITRDDNIAAFKRIRLRPRYLRDVSEVDTRTTIQ  65

Query:  76 GIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPK 135
           G ++S P+ +APT    +  P+GE++TARA                         P   +
Sbjct:  66 GEEISAPICIAPTGFHCLVWPDGEMSTARA-------------------------PEGLR 100

Query: 136 FFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANFA 195
           +FQLYV+ D  + ++L++R E  GF+A+ +T+DTP  G R  DIRN  QL  +L+L +  
Sbjct: 101 WFQLYVHPDLQLNKQLIQRVESLGFKALVITLDTPVCGNRRHDIRN--QLRRNLTLTDLQ 158

Query: 196 DMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWL 232
             K     KG A    +  +  + I  SL WND++W 
Sbjct: 159 SPK-----KGNA----IPYFQMTPISTSLCWNDLSWF 186

emb|CAC49551.1| hypothetical protein, similar to C-terminal part of L-lactate dehydrogenase (cytochrome) LldD [Sinorhizobium meliloti 1021]
ref|NP_437691.1| hypothetical protein, similar to C-terminal part of L-lactate dehydrogenase (cytochrome) LldD [Sinorhizobium meliloti 1021]
pir||G95985 hypothetical protein SMb20858 [imported] - Sinorhizobium meliloti (strain 1021) magaplasmid pSymB
(161 aa)

Score: 119 bits (297), Expect: 2.1143e-25
Length: 129, Idn/Pos/Gap = 55/87/0 (42%/67%/0%)

Query: 239 PILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFID 298
           P++LKG++  EDA+ A + GAD I +SNHG RQLDG  ++I  L  + ++V  +I V +D
Sbjct:  31 PLILKGILDPEDAKMAAKTGADAIIVSNHGGRQLDGAHSSISMLPRIVEAVGDQIEVHLD  90

Query: 299 SGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQK 358
            G+R G DV+KA+ALGA    IGRP ++GL   G+EG+   L +++ E    M LCG ++
Sbjct:  91 GGIRSGHDVLKAIALGAKGTYIGRPFLYGLGALGKEGMTLALDIIRKEMDTTMALCGKRR 150

Query: 359 VSDIRRDLV 367
           ++++ RD++
Sbjct: 151 ITEVGRDII 159

ref|XP_591592.1| PREDICTED: similar to glycolate oxidase; short-chain alpha-hydroxy acid oxidase, partial [Bos taurus]
(99 aa)

Score: 112 bits (279), Expect: 2.29962e-23
Length: 95, Idn/Pos/Gap = 54/71/0 (56%/74%/0%)

Query: 279 IDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYR 338
           ID L E+ ++V G++ VF+D GVR+GTDV+KALALGA AV +GRPI+WGLA  GE+GV  
Sbjct:   1 IDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIIWGLASQGEKGVQD  60

Query: 339 LLSLLKDEFKLAMQLCGCQKVSDIRRDLVVRDAFA 373
           +L +LK+EF LAM L GCQ V  I + LV ++  A
Sbjct:  61 VLEILKEEFWLAMALSGCQNVKVIDKTLVRKNPLA  95

ref|ZP_00130067.1| COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Desulfovibrio desulfuricans G20]
(340 aa)

Score: 108 bits (271), Expect: 1.8363e-22
Length: 127, Idn/Pos/Gap = 60/77/0 (47%/60%/0%)

Query: 241 LLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSG 300
           +LKG++T  DAQ A++ GAD I +SNHG R LD      + L E+A +V+GRI V  D G
Sbjct: 211 ILKGIMTVVDAQLAVEVGADAIVVSNHGGRVLDHTPGAAEVLPEIADAVKGRITVLADGG 270

Query: 301 VRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVS 360
           VR G DV+K LALGADAVLIGRP          EGV   L  L+ +   AM L GC+ V 
Sbjct: 271 VRDGFDVIKMLALGADAVLIGRPFSIAAVGGQAEGVAAYLEALRGQLVQAMVLTGCRSVQ 330

Query: 361 DIRRDLV 367
           +  R ++
Sbjct: 331 EAGRHIL 337

ref|NP_711669.1| L-lactate dehydrogenase [Leptospira interrogans serovar Lai str. 56601]
gb|AAN48687.1| L-lactate dehydrogenase [Leptospira interrogans serovar lai str. 56601]
(760 aa)

Score: 108 bits (271), Expect: 1.85168e-22
Length: 335, Idn/Pos/Gap = 88/141/48 (26%/42%/14%)

Query:  44 TLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGIDLSFPLMVAPT--AMQRMAHPEGELA 101
           T +DN  A R     P+ + + ++  +    +G     P+M AP   A+  M     E  
Sbjct: 454 TFQDNINALREYSILPKYIREHTQASVETHFLGKKFRTPVMAAPMTGAVTNMNGAMDEFT 513

Query: 102 TARAVARIGTVMGLSSWAT--TSLEDVAAHVPGLPKFFQLYVY-----KDRAITERLVRR 154
            A  +       G  +W     S E     +  + K     V      +D  + +   + 
Sbjct: 514 FAATLLEGCHTSGTLAWLGDGASPEKYLIMLEAIRKTKADAVLICKPREDEGLLKERFQE 573

Query: 155 AERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANFADMKDFAQVKGGAGASGLAS 214
           +E++G  AI + VD                        NF  M                 
Sbjct: 574 SEKSGLLAIGMDVDA----------------------VNFKTMT---------------- 595

Query: 215 YVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDG 274
            + ++   + N + +A ++S T+LP ++KG++T +DAQ A+  GAD I +SNHG R LD 
Sbjct: 596 -LKNISSITRNVSKLAKIRSFTKLPFIVKGIMTPQDAQLAIDAGADCIVVSNHGGRVLDD 654

Query: 275 VTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEE 334
           +  T   L  +   +  +I +  D GVR G DV K +ALGAD VL+GRP+       G  
Sbjct: 655 MPGTARVLSGIRNVIGDKIQIVADGGVRSGMDVFKMIALGADTVLVGRPMAIFAVGGGVA 714

Query: 335 GVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLVVR 369
           GV  L+S   D    +M + G + + DI  +L+ R
Sbjct: 715 GVRFLISQYTDNLLQSMNVTGTETLKDIGMELLFR 749

ref|YP_002203.1| putative glycolate oxidase [Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130]
gb|AAS70840.1| putative glycolate oxidase [Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130]
(760 aa)

Score: 107 bits (266), Expect: 7.84255e-22
Length: 335, Idn/Pos/Gap = 87/140/48 (25%/41%/14%)

Query:  44 TLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGIDLSFPLMVAPT--AMQRMAHPEGELA 101
           T +DN  A R     P+ + + ++  +    +G     P+M AP   A+  M     E  
Sbjct: 454 TFQDNINALREYSILPKYIREHTQASVEAHFLGKKFRTPVMAAPMTGAVTNMNGAMDEFT 513

Query: 102 TARAVARIGTVMGLSSWAT--TSLEDVAAHVPGLPKFFQLYVY-----KDRAITERLVRR 154
            A  +       G  +W     S E     +  + K     V      +D  + +   + 
Sbjct: 514 FAATLLEGCHTSGTLAWLGDGASPEKYLIMLEAIRKTKADAVLICKPREDEGLLKERFQE 573

Query: 155 AERAGFRAIALTVDTPQLGRREADIRNQFQLPPHLSLANFADMKDFAQVKGGAGASGLAS 214
           +E++G  AI + VD                        NF  M                 
Sbjct: 574 SEKSGLLAIGMDVDA----------------------VNFKTMT---------------- 595

Query: 215 YVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDG 274
            + ++   + N + +A ++S T+LP ++KG++  +DAQ A+  GAD I +SNHG R LD 
Sbjct: 596 -LKNISSITRNVSKLAKIRSFTKLPFIVKGIMAPQDAQLAIDAGADCIVVSNHGGRVLDD 654

Query: 275 VTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEE 334
           +  T   L  +   +  +I +  D GVR G DV K +ALGAD VL+GRP+       G  
Sbjct: 655 MPGTARVLSGIRNVIGDKIQIVADGGVRSGMDVFKMIALGADTVLVGRPMAIFAVGGGVA 714

Query: 335 GVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLVVR 369
           GV  L+S   D    +M + G + + DI  +L+ R
Sbjct: 715 GVRFLISQYTDNLLQSMNVTGTETLKDIGMELLFR 749

emb|CAG35572.1| hypothetical protein [Desulfotalea psychrophila LSv54]
ref|YP_064579.1| hypothetical protein DP0843 [Desulfotalea psychrophila LSv54]
(353 aa)

Score: 106 bits (265), Expect: 9.5017e-22
Length: 134, Idn/Pos/Gap = 56/83/0 (41%/61%/0%)

Query: 236 TRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPV 295
           T +  +LKGV+TA++A+ AL+ G + I +S+HG R LD    T + L E+A+ V+GR+ +
Sbjct: 220 TGMKFVLKGVMTADEAELALEAGCEAIVVSDHGGRVLDHTPGTAEVLPEIAERVKGRMTI 279

Query: 296 FIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCG 355
           F+D GVR G DV+K LALGADAV+IGRP         + GV + +  L  E K AM L G
Sbjct: 280 FVDGGVRTGGDVLKMLALGADAVMIGRPFSVAAVGGLQAGVEKYIDQLSTELKQAMTLTG 339

Query: 356 CQKVSDIRRDLVVR 369
               + +  +++ R
Sbjct: 340 TAAAASVSPNIIRR 353

gb|EAA73690.1| hypothetical protein FG05883.1 [Gibberella zeae PH-1]
ref|XP_386059.1| hypothetical protein FG05883.1 [Gibberella zeae PH-1]
(202 aa)

Score: 106 bits (265), Expect: 1.04151e-21
Length: 126, Idn/Pos/Gap = 57/83/4 (45%/65%/3%)

Query: 224 LNWNDIAWLKSITRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLE 283
           L+W+    +K+ T+LPI+LKG+ T EDA RA++ GADGIW+SNHG RQ+D   + ++   
Sbjct:  42 LSWDLFKEIKAHTKLPIILKGITTTEDALRAVEAGADGIWLSNHGGRQVDYSPSPLEIAY 101

Query: 284 EV---AQSVRGRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLL 340
           E+   A  +  +  V  DSG+R G+DV+K LALG  AV +GRP ++   V G EG  +L+
Sbjct: 102 EIRRNAPEIFAKTEVIADSGIRYGSDVIKLLALGVKAVGLGRPFMYS-NVYGVEGPKKLI 160

Query: 341 SLLKDE 346
            +LK E
Sbjct: 161 QILKSE 166

ref|YP_011996.1| dehydrogenase, FMN-dependent family [Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough]
gb|AAS97256.1| dehydrogenase, FMN-dependent family [Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough]
(341 aa)

Score: 101 bits (252), Expect: 3.24043e-20
Length: 128, Idn/Pos/Gap = 61/77/8 (47%/60%/6%)

Query: 241 LLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSG 300
           +LKG++ A+DA RA + G D I +SNHG R LD    T + L  +A +V+GR+ V +D G
Sbjct: 211 ILKGIMCADDALRAAEVGVDAIVVSNHGGRVLDHTPGTAEVLPAIADAVKGRLAVLVDGG 270

Query: 301 VRRGTDVVKALALGADAVLIGRPI----VWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGC 356
           VR G DV K LALGADAV+IGRP     V GLA    EGV   +  LK +   AM L G 
Sbjct: 271 VRDGVDVFKMLALGADAVMIGRPFSIAAVGGLA----EGVASYVDTLKAQLVQAMILTGS 326

Query: 357 QKVSDIRR 364
             V+ I R
Sbjct: 327 ADVAGISR 334

gb|AAV29920.1| NT02FT1138 [synthetic construct]
(185 aa)

Score: 97 bits (240), Expect: 9.0456e-19
Length: 161, Idn/Pos/Gap = 55/85/1 (34%/52%/0%)

Query:  15 NLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQV  74
           ++ + H  AK RLP +   Y  S +  +QT+ +NE+AFR++R       D S+ + T ++
Sbjct:   8 DITDMHKAAKKRLPRVFLDYIDSRSYQQQTVYENEQAFRKIRINQSAFKDCSQRNQTIEI  67

Query:  75 MGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLP 134
            G   S P  +APT +  M  P+GE+A A A  ++     +S+ A  SLE VA       
Sbjct:  68 FGFKSSVPFAIAPTGLAVMFWPKGEIALALAAEKLDIAYTMSTMAICSLETVAKEANN-H 126

Query: 135 KFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRR 175
            +FQLY+ K R  T+ L+ RA+  G + I +  D P  G R
Sbjct: 127 FWFQLYLMKARGFTKSLLERAKACGCQTIFVNADLPVSGIR 167

ref|NP_069641.1| L-lactate dehydrogenase, cytochrome-type (lldD) [Archaeoglobus fulgidus DSM 4304]
gb|AAB90435.1| L-lactate dehydrogenase, cytochrome-type (lldD) [Archaeoglobus fulgidus DSM 4304]
pir||G69350 L-lactate dehydrogenase, cytochrome-type (lldD) homolog - Archaeoglobus fulgidus
(366 aa)

Score: 93 bits (232), Expect: 6.98602e-18
Length: 141, Idn/Pos/Gap = 57/86/7 (40%/60%/4%)

Query: 228 DIAWLKSITRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQ 287
           ++A L S T+LP ++KGV++  D   +L   +  I +SNHG R LD   + ++ L  + +
Sbjct: 232 ELADLASTTKLPFIVKGVLSERD-YYSLADISSAIVVSNHGGRVLDSAISPLELLPYLEK 290

Query: 288 SVRGRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEF 347
            V    P  +DSG R G+DV KALALGAD VL GR +V+ LA+  E GV   L++++DE 
Sbjct: 291 VV----PTGVDSGFRYGSDVFKALALGADFVLFGRLMVYALAI--ENGVQTALNMIRDEL 344

Query: 348 KLAMQLCGCQKVSDIRRDLVV 368
              M+L G + V +I ++ VV
Sbjct: 345 LRIMKLTGAKSVKEISKEAVV 365

ref|NP_535707.1| dehydrogenase [Agrobacterium tumefaciens str. C58]
gb|AAL46023.1| dehydrogenase [Agrobacterium tumefaciens str. C58]
pir||AI3200 dehydrogenase Atu5335 [imported] - Agrobacterium tumefaciens (strain C58, Dupont) plasmid AT
(219 aa)

Score: 90 bits (222), Expect: 1.0004e-16
Length: 170, Idn/Pos/Gap = 56/85/2 (32%/50%/1%)

Query:  14 LNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQ  73
           L L ++   A+  LP  ++GY +  ++   +LR N E F    FRPRVL DVS+      
Sbjct:  12 LCLDDFEKAARRHLPRPLFGYVSGASETGASLRHNREDFADYAFRPRVLRDVSQRSTRTT  71

Query:  74 VMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGL 133
           ++G   S P  + P  +  +   +G+L  A+  ++ G  M +S  +   LE+V A  P  
Sbjct:  72 ILGESYSAPFGIVPMGISALMAYQGDLVLAQGASQAGIPMIMSGSSLIRLEEVVAKAPA- 130

Query: 134 PKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQF 183
             +FQ Y+  +    + LV R   AGF+   LTVDT  L  RE +IR  F
Sbjct: 131 -TWFQAYLPGEPERIDALVDRVAEAGFKTSVLTVDTSALANRENNIRAGF 179

ref|ZP_00321613.1| COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Haemophilus influenzae 86-028NP]
(183 aa)

Score: 90 bits (222), Expect: 1.04302e-16
Length: 165, Idn/Pos/Gap = 55/84/1 (33%/50%/0%)

Query:  17 AEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMG  76
           ++Y   A+ R+P  ++ Y   G+  EQTL  N      +  R RVL D+S +D + ++ G
Sbjct:   7 SDYREAARRRVPPFMFHYADGGSYAEQTLARNVSDLENIALRQRVLKDMSELDTSIELFG  66

Query:  77 IDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKF 136
             LS P ++AP     M    GE+  A+A    G    LS+ +   +E+VA  +   P +
Sbjct:  67 EKLSMPTILAPVGACGMYARRGEVQAAQAADNKGVPFTLSTVSICPIEEVAPAIK-RPMW 125

Query: 137 FQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRN 181
           FQLYV KDR   +  + RA+ AG   +  TVD P  G R  D+ +
Sbjct: 126 FQLYVLKDRGFMKNALERAKAAGCSTLVFTVDMPTPGARYRDMHS 170

ref|XP_582670.1| PREDICTED: similar to glycolate oxidase; short-chain alpha-hydroxy acid oxidase, partial [Bos taurus]
(96 aa)

Score: 86 bits (213), Expect: 1.06976e-15
Length: 89, Idn/Pos/Gap = 40/60/0 (44%/67%/0%)

Query:  16 LAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVM  75
           +++Y   AK+ L   +Y YY SGA+D++TL DN  AF R +  PR+L +++ +D++  V+
Sbjct:   8 ISDYEQHAKSVLQKSIYDYYKSGANDQETLADNIAAFSRWKLYPRMLRNIAEIDLSTSVL  67

Query:  76 GIDLSFPLMVAPTAMQRMAHPEGELATAR 104
           G  +S P+ V  TAMQ MAH +GELAT R
Sbjct:  68 GQKVSMPICVGATAMQCMAHVDGELATVR  96

dbj|BAD94421.1| glycolate oxidase like protein [Arabidopsis thaliana]
(80 aa)

Score: 81 bits (199), Expect: 4.92652e-14
Length: 74, Idn/Pos/Gap = 38/53/0 (51%/71%/0%)

Query: 301 VRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVS 360
           VRRGTDV KALALGA  + IGRP+V+ LA +GE GV ++L +L+DEF+L M L GC+ + 
Sbjct:   1 VRRGTDVFKALALGASGIFIGRPVVFSLAAEGEAGVRKVLQMLRDEFELTMALSGCRSLK  60

Query: 361 DIRRDLVVRDAFAP 374
           +I R+ +  +   P
Sbjct:  61 EISRNHITTEWDTP  74

gb|AAQ06983.1| lactate 2-monooxygenase [Lactobacillus delbrueckii subsp. lactis]
(128 aa)

Score: 80 bits (197), Expect: 7.2315e-14
Length: 114, Idn/Pos/Gap = 38/64/0 (33%/56%/0%)

Query:  73 QVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPG 132
           + +G+ L  P+M++P A   ++H + E+AT +  A  G +   S++    +E++AA  P 
Sbjct:   1 EFLGMKLKTPIMISPIACHGISHADAEVATQKGAALAGAMFTSSTYGNKPVEEIAAAAPD  60

Query: 133 LPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQLP 186
            P+ FQLY+ K+    + +      AG++AI LTVD    G REA++R  F  P
Sbjct:  61 APRMFQLYLSKNWDFNKMVFDAINAAGYKAILLTVDALVSGYREANLRTNFAFP 114

emb|CAC83303.1| putative (s)-2-hydroxy-acid oxidase [Pinus pinaster]
(79 aa)

Score: 80 bits (197), Expect: 7.53957e-14
Length: 70, Idn/Pos/Gap = 38/50/0 (54%/71%/0%)

Query: 302 RRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSD 361
           RRGTDV KALALGA  + IGRP+V+ LA +GE GV  +L +L+DEF+L M L GC  V +
Sbjct:   1 RRGTDVFKALALGASGIFIGRPVVFSLAAEGEAGVRNVLKMLRDEFELTMALAGCCSVKE  60

Query: 362 IRRDLVVRDA 371
           I R+ +  +A
Sbjct:  61 INRNYIQTEA  70

ref|NP_396268.1| hypothetical protein AGR_pAT_479 [Agrobacterium tumefaciens str. C58]
gb|AAK90709.1| AGR_pAT_479p [Agrobacterium tumefaciens str. C58]
(187 aa)

Score: 78 bits (192), Expect: 2.88904e-13
Length: 148, Idn/Pos/Gap = 52/74/3 (35%/50%/2%)

Query:  37 SGADDE-QTLRDNEEAFRRLRFRPRVLIDVSRVDITKQVMGIDLSFPLMVAPTAMQRMAH  95
           SGA +   +LR N E F    FRPRVL DVS+      ++G   S P  + P  +  +  
Sbjct:   2 SGASETGASLRHNREDFADYAFRPRVLRDVSQRSTRTTILGESYSAPFGIVPMGISALMA  61

Query:  96 PEGELATARAVARIGTVMGLSSWATTSLEDVAAHVPGLPKFFQLYVYKDRAITERLVRRA 155
            +G+L  A+  ++ G  M +S  +   LE+V A  P    +FQ Y+  +    + LV R 
Sbjct:  62 YQGDLVLAQGASQAGIPMIMSGSSLIRLEEVVAKAPA--TWFQAYLPGEPERIDALVDRV 119

Query: 156 ERAGFRAIALTVDTPQLGRREADIRNQF 183
             AGF+   LTVDT  L  RE +IR  F
Sbjct: 120 AEAGFKTSVLTVDTSALANRENNIRAGF 147

ref|XP_606384.1| PREDICTED: similar to Hydroxyacid oxidase 2 (HAOX2) ((S)-2-hydroxy-acid oxidase, peroxisomal) (Long chain alpha-hydroxy acid oxidase) (Long-chain L-2-hydroxy acid oxidase), partial [Bos taurus]
(207 aa)

Score: 76 bits (187), Expect: 1.29721e-12
Length: 61, Idn/Pos/Gap = 33/47/0 (54%/77%/0%)

Query: 218 SLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTA 277
           S ID S+ W D++W +S+TRLPI+LKG++T EDA+ A+++   GI +SNHG RQLD V A
Sbjct:  10 SPIDPSICWQDLSWFQSMTRLPIILKGILTKEDAELAVKHNVHGIIVSNHGGRQLDEVPA  69

Query: 278 T 278
           +
Sbjct:  70 S  70


Score: 70 bits (170), Expect: 9.45285e-11
Length: 51, Idn/Pos/Gap = 30/40/0 (58%/78%/0%)

Query: 279 IDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLA 329
           ID L EV  +V+G++ V++D G+R G DV+KALALGA  V +GRPI+WGLA
Sbjct: 155 IDALTEVVAAVKGKVEVYLDGGIRTGNDVLKALALGAKCVFVGRPILWGLA 205

ref|YP_194444.1| glycolate oxidase [Lactobacillus acidophilus NCFM]
gb|AAV43413.1| glycolate oxidase [Lactobacillus acidophilus NCFM]
(340 aa)

Score: 72 bits (177), Expect: 1.59855e-11
Length: 155, Idn/Pos/Gap = 49/80/2 (31%/51%/1%)

Query: 207 AGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQRALQYGADGIWISN 266
           AG +G    V  +   S+  +D+    + T LP + KGV++  DA +A Q G   I +S+
Sbjct: 176 AGENGKYDVVDGIPLGSIRMDDLKKYAASTELPFIAKGVLSVADALKARQAGCKAIVVSH 235

Query: 267 HGARQLDGVTATIDCLEEVAQSVRGR-IPVFIDSGVRRGTDVVKALALGADAVLIGRPIV 325
           H  R   G+   +  L E+ +++ G  + +F+D  +  G D  KALALGADAVLIGR I+
Sbjct: 236 HHGRVPFGIPP-LSILPEIKKALIGSGMQIFVDGSLMSGYDAYKALALGADAVLIGRGIL 294

Query: 326 WGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVS 360
             +  +G E     L  + ++    M   G + ++
Sbjct: 295 PEVLKNGTEATKNKLQKMNEQLSEMMLYTGIKDMN 329

gb|AAF03097.1| glycolate oxidase [Lactuca sativa]
(58 aa)

Score: 65 bits (159), Expect: 2.17798e-09
Length: 55, Idn/Pos/Gap = 32/42/0 (58%/76%/0%)

Query: 207 AGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQRALQYGADG 261
           A  SGLASYVA  ID +L+W D+ WL++IT + IL+KGV+TAED + A+Q GA G
Sbjct:   4 ANDSGLASYVAGQIDRTLSWKDVKWLQTITSMLILVKGVITAEDTRLAIQAGAAG  58

ref|ZP_00297154.1| COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Methanosarcina barkeri str. fusaro]
(365 aa)

Score: 60 bits (145), Expect: 9.62028e-08
Length: 86, Idn/Pos/Gap = 37/53/3 (43%/61%/3%)

Query: 285 VAQSVRGRI--PVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSL 342
           VA  +  R+  P+    G+R G D+ K++ALGA A     P V G A++G+E V R+LS 
Sbjct: 255 VASIIESRVSLPIIATGGIRTGIDIAKSIALGASAASAALPFV-GPALEGKESVVRVLSR 313

Query: 343 LKDEFKLAMQLCGCQKVSDIRRDLVV 368
           + DEF++AM LCGC  + D+R   VV
Sbjct: 314 MLDEFRIAMFLCGCANIQDLRNAPVV 339

ref|NP_971469.1| hypothetical protein TDE0859 [Treponema denticola ATCC 35405]
gb|AAS11350.1| conserved hypothetical protein [Treponema denticola ATCC 35405]
(308 aa)

Score: 59 bits (143), Expect: 1.43589e-07
Length: 132, Idn/Pos/Gap = 44/68/8 (33%/51%/6%)

Query: 228 DIAWLKSITRLPILLKGVVTAEDAQRALQYGADGIWISNHGAR-QLD--GVTATIDCLEE 284
           D+A LK   +LP  +KG+ T+ D +   +   D   ISNHG R + D   V A ++   +
Sbjct: 168 DLAALKKYAKLPFAVKGIFTSYDIEVVKELKPDIAIISNHGGRIETDRGSVAAFVNSHLK 227

Query: 285 VAQSVRGRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLL-SLL 343
             +   G   V+ D G+R+  D + A +LG + VLIGRP +  L  D E G+   + S+L
Sbjct: 228 EIKKYSGE--VWADGGLRKREDFMAASSLGIEEVLIGRPCITALLRDRENGIKNFIDSIL 285

Query: 344 KDEFKLAMQLCG 355
             +  L  + CG
Sbjct: 286 GKD--LTKEACG 295

gb|AAC65283.1| T. pallidum predicted coding region TP0291 [Treponema pallidum subsp. pallidum str. Nichols]
ref|NP_218732.1| hypothetical protein TP0291 [Treponema pallidum subsp. pallidum str. Nichols]
pir||F71344 hypothetical protein TP0291 - syphilis spirochete
(293 aa)

Score: 57 bits (138), Expect: 6.23568e-07
Length: 115, Idn/Pos/Gap = 37/56/1 (32%/48%/0%)

Query: 232 LKSITRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVA-QSVR 290
           ++   +LPI++KG+    D +   +   D   +SNHG R      +T D L E   +  R
Sbjct: 173 VRRFAKLPIVVKGIFAPRDVELVRELKPDVAIVSNHGGRVETARGSTADFLFEYGGELAR 232

Query: 291 GRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKD 345
               V++D G+R    +  A  LGA  VLIGRP +  L   G+ GV  L+  + D
Sbjct: 233 CAGEVWVDGGIRSYAHLCAARELGAQQVLIGRPFITALLKGGKGGVQLLVRNMTD 287

gb|AAB27970.1| FMN-dependent membrane-bound L(+)-mandelate dehydrogenase {N-terminal} [Pseudomonas putida, Peptide Partial, 58 aa]
(58 aa)

Score: 56 bits (134), Expect: 1.71137e-06
Length: 53, Idn/Pos/Gap = 23/35/0 (43%/66%/0%)

Query: 14 LNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVS 66
           N+ +Y   A+ RLP MVY Y   GA+DE  ++ N + F++ RF+P+ L+DVS
Sbjct:  6 FNVEDYRKLAQKRLPKMVYDYLEGGAEDEYGVKHNRDVFQQWRFKPKRLVDVS 58

ref|NP_633788.1| Isopentenyl-diphosphate delta-isomerase [Methanosarcina mazei Go1]
gb|AAM31460.1| Isopentenyl-diphosphate delta-isomerase [Methanosarcina mazei Goe1]
sp|Q8PW37|IDI2_METMA Isopentenyl-diphosphate delta-isomerase (IPP isomerase) (Isopentenyl pyrophosphate isomerase)
(365 aa)

Score: 55 bits (131), Expect: 3.81254e-06
Length: 79, Idn/Pos/Gap = 33/48/1 (41%/60%/1%)

Query: 290 RGRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKL 349
           R  +P+    G+R G D+ K++ALGA A     P V G +++G+E V R+LS + +EFK 
Sbjct: 262 RVSLPLIATGGIRNGLDIAKSIALGASAASAALPFV-GPSLEGKESVVRVLSCMLEEFKA 320

Query: 350 AMQLCGCQKVSDIRRDLVV 368
           AM LCGC  + D+    VV
Sbjct: 321 AMFLCGCGNIKDLHNSPVV 339

sp|Q8TX99|IDI2_METKA Isopentenyl-diphosphate delta-isomerase (IPP isomerase) (Isopentenyl pyrophosphate isomerase)
(365 aa)

Score: 54 bits (130), Expect: 5.23496e-06
Length: 325, Idn/Pos/Gap = 77/130/58 (23%/40%/17%)

Query:  63 IDVSRVDITKQVMGIDLSFPLMVAPTAMQRMAHPE-GELATARAVARIGTVMGLSSWATT 121
           +D   VD+  ++ G  LSFPL++A        HP+ GE+   R +AR+   + +     +
Sbjct:  38 LDFDDVDMEIELFGKRLSFPLIIAGMTG---GHPKTGEIN--RKLARVARELEIGIGVGS  92

Query: 122 SLEDVAAHVPGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRN 181
               V    P +   F++       + E        A      L  + P L     D+ +
Sbjct:  93 QRAGVKD--PEVRWTFEV-------VREEYPDGLVLANIGLPQLRENGPDLALEVVDMVD 143

Query: 182 QFQLPPHLSLANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPIL 241
              L  H+++     +++  Q++G A A+G    +A + +                +P++
Sbjct: 144 ADALAVHVNV-----LQEAVQLEGEADAAGFVDVLAEVCET-------------VDVPVV 185

Query: 242 LKGV---VTAEDAQRALQYGADGIWISNHGARQLDGVTA--------------------- 277
           LK     V+AEDA + ++   DGI +   G      V A                     
Sbjct: 186 LKETGAGVSAEDA-KLVRDIVDGIDVGGAGGTNWAVVEAVRSKAHGEIPLGYAFSDWGVP 244

Query: 278 TIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVY 337
           T   + EV   V   + +    GVR G DV K LALGAD   +  P++  +  +G  G  
Sbjct: 245 TAASILEVRSVVGNDLAIIGTGGVRTGMDVAKVLALGADCAGMALPVLRKVLAEGVRGCV 304

Query: 338 RLLSLLKDEFKLAMQLCGCQKVSDI 362
           R L  +  E K+AM + GC  V ++
Sbjct: 305 RFLKSIAREVKIAMLMAGCSSVEEM 329

ref|NP_614060.1| L-lactate dehydrogenase (FMN-dependent) [Methanopyrus kandleri AV19]
gb|AAM01990.1| L-lactate dehydrogenase (FMN-dependent) [Methanopyrus kandleri AV19]
(374 aa)

Score: 54 bits (129), Expect: 5.36765e-06
Length: 325, Idn/Pos/Gap = 77/130/58 (23%/40%/17%)

Query:  63 IDVSRVDITKQVMGIDLSFPLMVAPTAMQRMAHPE-GELATARAVARIGTVMGLSSWATT 121
           +D   VD+  ++ G  LSFPL++A        HP+ GE+   R +AR+   + +     +
Sbjct:  47 LDFDDVDMEIELFGKRLSFPLIIAGMTG---GHPKTGEIN--RKLARVARELEIGIGVGS 101

Query: 122 SLEDVAAHVPGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRN 181
               V    P +   F++       + E        A      L  + P L     D+ +
Sbjct: 102 QRAGVKD--PEVRWTFEV-------VREEYPDGLVLANIGLPQLRENGPDLALEVVDMVD 152

Query: 182 QFQLPPHLSLANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPIL 241
              L  H+++     +++  Q++G A A+G    +A + +                +P++
Sbjct: 153 ADALAVHVNV-----LQEAVQLEGEADAAGFVDVLAEVCET-------------VDVPVV 194

Query: 242 LKGV---VTAEDAQRALQYGADGIWISNHGARQLDGVTA--------------------- 277
           LK     V+AEDA + ++   DGI +   G      V A                     
Sbjct: 195 LKETGAGVSAEDA-KLVRDIVDGIDVGGAGGTNWAVVEAVRSKAHGEIPLGYAFSDWGVP 253

Query: 278 TIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVY 337
           T   + EV   V   + +    GVR G DV K LALGAD   +  P++  +  +G  G  
Sbjct: 254 TAASILEVRSVVGNDLAIIGTGGVRTGMDVAKVLALGADCAGMALPVLRKVLAEGVRGCV 313

Query: 338 RLLSLLKDEFKLAMQLCGCQKVSDI 362
           R L  +  E K+AM + GC  V ++
Sbjct: 314 RFLKSIAREVKIAMLMAGCSSVEEM 338

ref|ZP_00147456.2| COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Methanococcoides burtonii DSM 6242]
(362 aa)

Score: 54 bits (129), Expect: 5.45798e-06
Length: 99, Idn/Pos/Gap = 33/52/12 (33%/52%/12%)

Query: 290 RGRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKL 349
           R  +PV    GVR G D+ K+L+LGA A     P V G A+ G + V   LS + +E ++
Sbjct: 259 RSFVPVVATGGVRTGLDIAKSLSLGAYAASAALPFV-GPALIGADEVVSSLSKMLNELRV 317

Query: 350 AMQLCGCQKVSDIR-----------RDLVVRDAFAPYDV 377
           AM LCGC  ++++R           ++ + +  F P D+
Sbjct: 318 AMFLCGCGNINELRTSSKVTVTGWTKEYITQRGFDPKDL 356

ref|NP_615568.1| isopentenyl-diphosphate delta-isomerase [Methanosarcina acetivorans C2A]
gb|AAM04048.1| isopentenyl-diphosphate delta-isomerase [Methanosarcina acetivorans str. C2A]
sp|Q8TT35|IDI2_METAC Isopentenyl-diphosphate delta-isomerase (IPP isomerase) (Isopentenyl pyrophosphate isomerase)
(365 aa)

Score: 54 bits (129), Expect: 5.64321e-06
Length: 171, Idn/Pos/Gap = 52/81/24 (30%/47%/14%)

Query: 221 DASLNWNDIAWLKSITRLPILLKGV---VTAEDAQRALQYGADGIWISNHGARQLDGVTA 277
           DA+   + IA + S+ R+P++ K     ++ EDA    + G   I +   G     GV  
Sbjct: 170 DATGCLDMIAEICSMVRIPVIAKETGAGISREDALLLHKAGVSAIDVGGVGGTSWAGVEV 229

Query: 278 -----TIDCLEE-------------VAQSVRGRI--PVFIDSGVRRGTDVVKALALGADA 317
                + D + E             VA  +  R+  P+    GVR G D+ K++ALGA A
Sbjct: 230 YRAKESKDPVSERLGELFWDFGIPTVASLIESRVSLPLIATGGVRTGLDIAKSIALGASA 289

Query: 318 VLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLVV 368
                P V G +++G+E V ++LS + DEF+ AM LCGC  +  +    VV
Sbjct: 290 ASAALPFV-GPSLEGKESVVKVLSCMLDEFRAAMFLCGCANIQALHNSPVV 339

emb|CAI29178.1| isopentenyl-pyrophosphate isomerase [Leishmania major]
(357 aa)

Score: 53 bits (128), Expect: 7.30902e-06
Length: 158, Idn/Pos/Gap = 41/70/27 (25%/44%/17%)

Query: 237 RLPILLKGVVTAEDAQRALQYGADGI------------WISNHGARQ------------L 272
           ++P+L+KGV    D +  +   A G+            W    G RQ            L
Sbjct: 196 KVPVLVKGVGHGIDYESMVAIKASGVKYVDVSGCGGTSWAWIEGRRQPYKAEEENIGYLL 255

Query: 273 DGVTATID-CLEEVAQ-SVRGRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAV 330
             +    D CL E A  +V G + +    G+R G DV KAL +GA+      P +   A+
Sbjct: 256 RDIGVPTDVCLRESAPLTVNGDLHLIAGGGIRNGMDVAKALMMGAEYATAAMPFL-AAAL 314

Query: 331 DGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLVV 368
           +  E V  ++  ++ E +++M  CG + + ++RR  V+
Sbjct: 315 ESSEAVRAVIQRMRQELRVSMFTCGARNIEELRRMKVI 352

emb|CAH15927.1| hypothetical protein [Legionella pneumophila str. Lens]
ref|YP_127026.1| hypothetical protein lpl1687 [Legionella pneumophila str. Lens]
(490 aa)

Score: 51 bits (123), Expect: 2.84782e-05
Length: 152, Idn/Pos/Gap = 44/71/24 (28%/46%/15%)

Query: 194 FADMKDFAQVKGGAG---ASGLASYVASLIDASLN--------------WNDIAWLK-SI 235
           +A    F Q++ GA      G    VA+L+++ ++               N + W+K + 
Sbjct: 209 YACKDSFEQLRVGAAVGVGEGTDERVAALVESGVDVIVVDTAHGHSQGVLNRVKWIKKNY 268

Query: 236 TRLPILLKGVVTAEDAQRALQYGADGIWI-----SNHGARQLDGV-TATIDCLEEVAQSV 289
             + ++   + TA  A+   + GAD + +     S    R + GV    I  +  VAQ +
Sbjct: 269 PDVQVIGGNIATAAAARDLYEAGADAVKVGIGPGSICTTRIVTGVGIPQISAIANVAQEL 328

Query: 290 RGRIPVFIDSGVRRGTDVVKALALGADAVLIG 321
           +G IPV  D G+R   DV KALA GAD V++G
Sbjct: 329 KGIIPVIADGGIRFSGDVCKALAAGADTVMLG 360

ref|YP_095750.1| inosine-5'-monophosphate dehydrogenase [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
emb|CAH12840.1| hypothetical protein [Legionella pneumophila str. Paris]
ref|YP_124006.1| hypothetical protein lpp1688 [Legionella pneumophila str. Paris]
gb|AAU27803.1| inosine-5'-monophosphate dehydrogenase [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
(490 aa)

Score: 51 bits (123), Expect: 2.84782e-05
Length: 152, Idn/Pos/Gap = 44/71/24 (28%/46%/15%)

Query: 194 FADMKDFAQVKGGAG---ASGLASYVASLIDASLN--------------WNDIAWLK-SI 235
           +A    F Q++ GA      G    VA+L+++ ++               N + W+K + 
Sbjct: 209 YACKDSFEQLRVGAAVGVGEGTDERVAALVESGVDVIVVDTAHGHSQGVLNRVKWIKKNY 268

Query: 236 TRLPILLKGVVTAEDAQRALQYGADGIWI-----SNHGARQLDGV-TATIDCLEEVAQSV 289
             + ++   + TA  A+   + GAD + +     S    R + GV    I  +  VAQ +
Sbjct: 269 PDVQVIGGNIATAAAARDLYEAGADAVKVGIGPGSICTTRIVTGVGIPQISAIANVAQEL 328

Query: 290 RGRIPVFIDSGVRRGTDVVKALALGADAVLIG 321
           +G IPV  D G+R   DV KALA GAD V++G
Sbjct: 329 KGIIPVIADGGIRFSGDVCKALAAGADTVMLG 360

gb|EAL49309.1| isopentenyl-diphosphate delta-isomerase, putative [Entamoeba histolytica HM-1:IMSS]
(358 aa)

Score: 51 bits (123), Expect: 2.84782e-05
Length: 70, Idn/Pos/Gap = 22/42/1 (31%/60%/1%)

Query: 293 IPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQ 352
           +P+    G+R G ++VK++ LGA    I +P V  L ++G E     ++ +K+E + ++ 
Sbjct: 264 LPIIASGGIRNGLEIVKSMTLGASLASITKPFV-SLYLEGSEACINYVNFIKNEIQSSLF 322

Query: 353 LCGCQKVSDI 362
           LCGC  V+++
Sbjct: 323 LCGCPSVNEV 332

gb|AAU82528.1| conserved hypothetical protein [uncultured archaeon GZfos18C8]
(109 aa)

Score: 51 bits (122), Expect: 3.91032e-05
Length: 100, Idn/Pos/Gap = 35/52/5 (35%/52%/5%)

Query: 285 VAQSVRGRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLK 344
           V + V   +PV    GVR G D+ K++ALGA       P+V   A+   + V   LS + 
Sbjct:  13 VVECVSCGLPVIATGGVRTGIDIAKSIALGASLSGTALPLV-APAMKNADAVIDRLSSMI  71

Query: 345 DEFKLAMQLCGCQKVSDIRRDLVVRDAFAPYDVRQMLSVK 384
            E ++AM LCGC+ V+D++   VV        VR+ML  +
Sbjct:  72 SELEIAMFLCGCRDVADLKTAPVVIGG----RVREMLDAR 107

gb|AAU83074.1| L-lactate dehydrogenase [uncultured archaeon GZfos26E7]
(375 aa)

Score: 50 bits (119), Expect: 8.08107e-05
Length: 92, Idn/Pos/Gap = 32/48/5 (34%/52%/5%)

Query: 293 IPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQ 352
           +PV    GVR G D+ K++ALGA       P+V   A+   + V   LS +  E ++AM 
Sbjct: 287 LPVIATGGVRTGIDIAKSIALGASLSGTALPLV-APAMKNADAVIDRLSCMISELEIAMF 345

Query: 353 LCGCQKVSDIRRDLVVRDAFAPYDVRQMLSVK 384
           LCGC  V+D++   VV        +R+ML  +
Sbjct: 346 LCGCPDVADLKTAPVVIGG----RIREMLDAR 373

emb|CAI29176.1| isopentenyl-pyrophosphate isomerase [Trypanosoma brucei brucei]
(356 aa)

Score: 50 bits (119), Expect: 8.71127e-05
Length: 92, Idn/Pos/Gap = 30/51/3 (32%/55%/3%)

Query: 274 GVTATIDCLEEVAQ-SVRGRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDG 332
           GVT T  CL E A  + +G + +    G+R G D+ K+L +GA+      P +   A++G
Sbjct: 258 GVT-TDQCLTECAPLAKKGGLHLIAGGGIRTGLDIAKSLMMGAECATAALPFLKA-ALEG 315

Query: 333 EEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRR 364
            E V +++  L+ E  +AM  CG + ++ +RR
Sbjct: 316 PEAVRKVIQRLRRELVVAMFACGVKDIASLRR 347

ref|NP_757703.1| inosine-5'-monophosphate dehydrogenase [Mycoplasma penetrans HF-2]
dbj|BAC44107.1| inosine-5'-monophosphate dehydrogenase [Mycoplasma penetrans HF-2]
(483 aa)

Score: 49 bits (117), Expect: 0.000131111
Length: 99, Idn/Pos/Gap = 35/52/13 (35%/52%/13%)

Query: 233 KSITRLPILLKGVVTAEDAQRALQYGADGIWIS-NHGA----RQLDGV-----TATIDCL 282
           K   +L +++  VVTA       + GAD + I    GA    R + GV     +A ++C 
Sbjct: 268 KLFPKLFLIVGNVVTANGVNDLYKAGADAVKIGVGPGAICTTRTVSGVGIPQFSAILECY 327

Query: 283 EEVAQSVRGRIPVFIDSGVRRGTDVVKALALGADAVLIG 321
           EE  +     IP+  D G++   D+VKALA GADAV++G
Sbjct: 328 EEAKKL---NIPIIADGGIKNSGDMVKALAAGADAVMLG 363

gb|AAB84555.1| conserved protein [Methanothermobacter thermautotrophicus str. Delta H]
ref|NP_275191.1| hypothetical protein MTH48 [Methanothermobacter thermautotrophicus str. Delta H]
pir||H69162 conserved hypothetical protein MTH48 - Methanobacterium thermoautotrophicum (strain Delta H)
sp|O26154|IDI2_METTH Isopentenyl-diphosphate delta-isomerase (IPP isomerase) (Isopentenyl pyrophosphate isomerase)
(349 aa)

Score: 49 bits (116), Expect: 0.000190855
Length: 327, Idn/Pos/Gap = 66/129/60 (20%/39%/18%)

Query:  63 IDVSRVDITKQVMGIDLSFPLMVAPTAMQRMAHPEGELATARAVARIGTVMGLSSWATTS 122
           I+  ++DI+   +G +LS P+M++       A  +     ARA  ++G  +GL S     
Sbjct:  39 INKEKIDISLDFLGRELSSPVMISAITGGHPASMKINRELARAAEKLGIALGLGS-----  93

Query: 123 LEDVAAHVPGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQ 182
            +      P L   +   + ++ A +  L+     +            +   R  ++ + 
Sbjct:  94 -QRAGVEHPELEGTYT--IAREEAPSAMLIGNIGSSHI----------EYAERAVEMIDA 140

Query: 183 FQLPPHLSLANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILL 242
             L  HL+      +++  Q  G   +SG    +++++++               +P+++
Sbjct: 141 DALAVHLN-----PLQESIQPGGDVDSSGALESISAIVES-------------VDVPVMV 182

Query: 243 KGV---VTAEDAQRALQYGADGIWISNHGARQLDGVTA------------------TIDC 281
           K     + +EDA      G   I ++  G      V                    T   
Sbjct: 183 KETGAGICSEDAIELESCGVSAIDVAGAGGTSWAAVETYRADDRYLGELFWDWGIPTAAS 242

Query: 282 LEEVAQSVRGRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLS 341
             EV +SV   IPV    G+R G D  KA++LGA+ V I  P++   A  G   V +++ 
Sbjct: 243 TVEVVESVS--IPVIASGGIRSGIDAAKAISLGAEMVGIALPVLEA-AGHGYREVIKVIE 299

Query: 342 LLKDEFKLAMQLCGCQKVSDIRRDLVV 368
              +  + AM L G + + D+++  V+
Sbjct: 300 GFNEALRTAMYLAGAETLDDLKKSPVI 326

ref|YP_181129.1| IMP dehydrogenase family protein [Dehalococcoides ethenogenes 195]
gb|AAW40323.1| IMP dehydrogenase family protein [Dehalococcoides ethenogenes 195]
(381 aa)

Score: 49 bits (116), Expect: 0.000202334
Length: 146, Idn/Pos/Gap = 44/72/17 (30%/49%/11%)

Query: 195 ADMKDFAQVKGGAGAS--GLASYVASLIDASLNWNDIAW--LKSITRLPILLKGVVTAED 250
           A+ K  A V   AGA    +AS V S    S + + + +     + ++P+L+   V+ + 
Sbjct: 139 ANAKKLAPVAVEAGADIISVASTVTSARHVSKSSHGLIFEEFVKMIKVPVLVGNCVSYQA 198

Query: 251 AQRALQYGADGIWIS-NHGA----RQLDGV-----TATIDCL--EEVAQSVRGR-IPVFI 297
               ++ G  G+ I    GA    R++ G+     TA++DC    E      GR +P+  
Sbjct: 199 CLELMRTGVHGVIIGVGPGAACTSREVLGIGVPQITASMDCAAARETYYKETGRYVPIIT 258

Query: 298 DSGVRRGTDVVKALALGADAVLIGRP 323
           D G ++G DV KA+  GADAV++G P
Sbjct: 259 DGGFKKGGDVCKAICAGADAVMLGSP 284

ref|ZP_00177788.1| COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Crocosphaera watsonii WH 8501]
(356 aa)

Score: 48 bits (114), Expect: 0.000365888
Length: 328, Idn/Pos/Gap = 78/128/61 (23%/39%/18%)

Query:  63 IDVSRVDITKQVMGIDLSFPLMVAP-TAMQRMAHPEGELATARAVARIGTVMGLSSWATT 121
           +D+  VD++ QV G  L  PL+++  T     AH    L  A     +G  MG+ S    
Sbjct:  50 VDLDEVDLSLQVWGKTLQAPLLISSMTGGTDNAHFI-NLNLAETAQALGIAMGVGS---- 104

Query: 122 SLEDVAAHVPGLPKFFQLYVYKDRAITERLVRRAERAGFRA-IALTVDTPQLGRREADIR 180
             +      P L K +Q+     R +   ++  A     +      +D     ++  D+ 
Sbjct: 105 --QRAGIEQPNLGKTYQI-----RGVAPDILLFANLGAVQLNYGYGIDE---AKKAVDMI 154

Query: 181 NQFQLPPHLSLANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPI 240
               L  HL+      +++  Q +G     GL             +N IA L +   +PI
Sbjct: 155 EADALILHLN-----PLQEAVQAEGDRNWKGL-------------YNKIATLATKLDVPI 196

Query: 241 LLKGV---VTAEDAQRALQYGADGIWISNHGARQLDGVTA-------------------- 277
           + K V   ++ + A+R    G   I I+  G      V A                    
Sbjct: 197 IAKEVGNGISGKIARRLADCGVSAIDIAGAGGTSWSEVEAYRESDPRRRQIAHCFAGWGI 256

Query: 278 -TIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGV 336
            T   L +V ++V   +PVF   G+R G DV KA+ALGA  V    P++   A    + V
Sbjct: 257 PTAVSLMQVRKAVP-ELPVFASGGIRSGIDVAKAIALGATLVGSAAPLL-DAATYQSQAV 314

Query: 337 YRLLSLLKDEFKLAMQLCGCQKVSDIRR 364
           Y   S+L +  K+A    G   +S +++
Sbjct: 315 YDKFSILLETLKIATFCAGSSNLSQLKQ 342

emb|CAB49977.1| fnI isopentenyl-diphosphate delta-isomerase (IPP isomerase) (EC 5.3.3.2) [Pyrococcus abyssi GE5]
ref|NP_126746.1| carotenoid biosynthetic gene erwcrts related [Pyrococcus abyssi GE5]
pir||D75084 carotenoid biosynthetic gene erwcrts related PAB1662 - Pyrococcus abyssi (strain Orsay)
sp|Q9UZS9|IDI2_PYRAB Isopentenyl-diphosphate delta-isomerase (IPP isomerase) (Isopentenyl pyrophosphate isomerase)
(370 aa)

Score: 48 bits (113), Expect: 0.000469957
Length: 333, Idn/Pos/Gap = 80/137/48 (24%/41%/14%)

Query:  63 IDVSRVDITKQVMGIDLSFPLMVAPTAMQRMAHPEGELA------TARAVARIGTVMGLS 116
           ID   +D++ + +G    +P+M+  T M      +GE+A       A+A   +   +GL 
Sbjct:  42 IDKDEIDLSVKFLGRKFDYPIMI--TGMTGGTR-KGEIAWRINRTLAQAAQELNIPLGLG  98

Query: 117 S----------WATTSLEDVAAHV-----PGLPKFFQLYVYKDRAITERLVRRAERAGFR 161
           S          W +  + DVA  V      G P+F +    K R   + ++   E+    
Sbjct:  99 SQRAMIEKPETWESYYVRDVAPDVFLVGNLGAPQFGR--NAKKRYSVDEVLYAIEKIEAD 156

Query: 162 AIALTVDTPQLG-RREADIRNQFQLPPHLSLANFADMKDFAQVKGGAGASGLASYVASLI 220
           AIA+ ++  Q   + E D      L    +LA      D+  +    GA G++  VA  +
Sbjct: 157 AIAIHMNPLQESIQPEGDTTFSGVLE---ALAEITSTIDYPVIAKETGA-GVSKEVAVEL 212

Query: 221 DA-SLNWNDIAWLKSITRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATI 279
           +A  ++  DI+ L   +   +        E    AL++   GI               T 
Sbjct: 213 EAVGVDAIDISGLGGTSWSAVEYYRTKDGEKRNLALKFWDWGI--------------KTA 258

Query: 280 DCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRL 339
             L EV  +    +P+    G+R G  + KALA+GA  V I  P++   A    EGV R+
Sbjct: 259 ISLAEVRWATN--LPIIASGGMRDGITMAKALAMGASMVGIALPVLRPAAKGDVEGVIRI 316

Query: 340 LSLLKDEFKLAMQLCGCQKVSDIRRDLVVRDAF 372
           +    +E +  M L G + + ++R+  +V   F
Sbjct: 317 IKGYAEEIRNVMFLVGARNIKELRKVPLVITGF 349

sp|O27997|IDI2_ARCFU Isopentenyl-diphosphate delta-isomerase (IPP isomerase) (Isopentenyl pyrophosphate isomerase)
(345 aa)

Score: 47 bits (112), Expect: 0.000583811
Length: 334, Idn/Pos/Gap = 74/125/78 (22%/37%/23%)

Query:  63 IDVSRVDITKQVMGIDLSFPLMVAPTAMQRMAHPEGELATAR---AVARIGTVMGLSSWA 119
           +D  ++D   +  G  LSFPL++A        HPE +   AR   AV   G  MG+ S  
Sbjct:  39 VDYWKIDTEIEFFGKKLSFPLLIASMTG---GHPETKEINARLGEAVEEAGIGMGVGS--  93

Query: 120 TTSLEDVAAHVPGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADI 179
                             Q    +D ++ +      E+A    +   +  PQ+  R  +I
Sbjct:  94 ------------------QRAAIEDESLADSFTVVREKAPNAFVYANIGMPQVIERGVEI 135

Query: 180 RNQFQLPPHLSLANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSI---- 235
            ++             +M D         A  +A ++  L +A     D+   K +    
Sbjct: 136 VDRA-----------VEMID---------ADAVAIHLNYLQEAIQPEGDLNAEKGLEVLE 175

Query: 236 -----TRLPILLKGV---VTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQ 287
                 ++P++ K     ++ E A    + G   I +   G     GV       +EV++
Sbjct: 176 EVCRSVKVPVIAKETGAGISREVAVMLKRAGVSAIDVGGKGGTTFSGVE-VYRVNDEVSK 234

Query: 288 SV------------------RGRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLA 329
           SV                  RG +PV    G+R G DV K++A+GA+      P +   A
Sbjct: 235 SVGIDFWDWGLPTAFSIVDCRGILPVIATGGLRSGLDVAKSIAIGAELGSAALPFLRA-A 293

Query: 330 VDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIR 363
           V+  E V   +   +   K AM L GC+ V +++
Sbjct: 294 VESAEKVREEIEYFRRGLKTAMFLTGCKNVEELK 327

ref|NP_349307.1| IMP dehydrogenase [Clostridium acetobutylicum ATCC 824]
gb|AAK80647.1| IMP dehydrogenase [Clostridium acetobutylicum ATCC 824]
pir||D97232 IMP dehydrogenase (EC 1.1.1.205) [similarity] - Clostridium acetobutylicum
(485 aa)

Score: 47 bits (111), Expect: 0.000650699
Length: 137, Idn/Pos/Gap = 39/62/15 (28%/45%/10%)

Query: 233 KSITRLPILLKGVVTAEDAQRALQYGADGIWI-----SNHGARQLDGV-----TATIDCL 282
           K+   L ++   V TA      ++ GAD + +     S    R + G+     TA +DC+
Sbjct: 265 KAYPELQVIAGNVATAAAVHDLIEAGADCVKVGIGPGSICTTRVVAGIGVPQLTAVMDCV 324

Query: 283 EEVAQSVRGRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVY--RLL 340
           EE  +     +P+  D G++   D+VKALA GA AV++G          GE  +Y  R  
Sbjct: 325 EEANKY---GVPIIADGGIKYSGDIVKALAAGAKAVMMGSMFAGCEEAPGETEIYQGRSY 381

Query: 341 SLLKDEFKLAMQLCGCQ 357
            + +    LA   CG +
Sbjct: 382 KVYRGMGSLAAMQCGSK 398

ref|ZP_00328609.1| COG0516: IMP dehydrogenase/GMP reductase [Trichodesmium erythraeum IMS101]
(219 aa)

Score: 47 bits (111), Expect: 0.00076887
Length: 133, Idn/Pos/Gap = 42/60/24 (31%/45%/18%)

Query: 221 DASLNWNDIAWLKSITRLPILLKGVVTAEDAQRALQYGADGIWIS-NHGA----RQLDGV 275
           D S+   D+  L     +P++L   VT E A   ++ GA G+ +    GA    R + GV
Sbjct:   3 DESVEKLDLVKLCQEMPMPVVLGNCVTYEVALSLMKAGAAGVLVGIGPGAACTSRGVLGV  62

Query: 276 -----TATIDCL---EEVAQSVRGRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIV-- 325
                TA  DC     +  Q     +PV  D G+  G D+ K++A GAD V+IG PI   
Sbjct:  63 GVPQVTAIADCAAARNDYYQVTGNYVPVIADGGLITGGDICKSIACGADGVMIGSPIARA 122

Query: 326 ---------WGLA 329
                    WG+A
Sbjct: 123 AEAPGAGYHWGMA 135

ref|NP_071112.1| carotenoid biosynthetic gene ERWCRTS, putative [Archaeoglobus fulgidus DSM 4304]
gb|AAB88970.1| carotenoid biosynthetic gene ERWCRTS, putative [Archaeoglobus fulgidus DSM 4304]
pir||G69535 carotenoid biosynthetic protein ERWCRTS homolog - Archaeoglobus fulgidus
(317 aa)

Score: 47 bits (111), Expect: 0.000781808
Length: 334, Idn/Pos/Gap = 74/125/78 (22%/37%/23%)

Query:  63 IDVSRVDITKQVMGIDLSFPLMVAPTAMQRMAHPEGELATAR---AVARIGTVMGLSSWA 119
           +D  ++D   +  G  LSFPL++A        HPE +   AR   AV   G  MG+ S  
Sbjct:  11 VDYWKIDTEIEFFGKKLSFPLLIASMTG---GHPETKEINARLGEAVEEAGIGMGVGS--  65

Query: 120 TTSLEDVAAHVPGLPKFFQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLGRREADI 179
                             Q    +D ++ +      E+A    +   +  PQ+  R  +I
Sbjct:  66 ------------------QRAAIEDESLADSFTVVREKAPNAFVYANIGMPQVIERGVEI 107

Query: 180 RNQFQLPPHLSLANFADMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSI---- 235
            ++             +M D         A  +A ++  L +A     D+   K +    
Sbjct: 108 VDRA-----------VEMID---------ADAVAIHLNYLQEAIQPEGDLNAEKGLEVLE 147

Query: 236 -----TRLPILLKGV---VTAEDAQRALQYGADGIWISNHGARQLDGVTATIDCLEEVAQ 287
                 ++P++ K     ++ E A    + G   I +   G     GV       +EV++
Sbjct: 148 EVCRSVKVPVIAKETGAGISREVAVMLKRAGVSAIDVGGKGGTTFSGVE-VYRVNDEVSK 206

Query: 288 SV------------------RGRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLA 329
           SV                  RG +PV    G+R G DV K++A+GA+      P +   A
Sbjct: 207 SVGIDFWDWGLPTAFSIVDCRGILPVIATGGLRSGLDVAKSIAIGAELGSAALPFLRA-A 265

Query: 330 VDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIR 363
           V+  E V   +   +   K AM L GC+ V +++
Sbjct: 266 VESAEKVREEIEYFRRGLKTAMFLTGCKNVEELK 299

gb|EAK87356.1| inosine-5-monophosphate dehydrogenase [EC:1.1.1.205] [Cryptosporidium parvum]
(402 aa)

Score: 46 bits (110), Expect: 0.000849839
Length: 97, Idn/Pos/Gap = 33/50/7 (34%/51%/7%)

Query: 232 LKSITRLPILLKGVVTAEDAQRALQYGADGIWI-----SNHGARQLDGVTATIDCLEEVA 286
           +KS   + +++  VVT E  +  ++ GADGI +     S    R + GV        E  
Sbjct: 181 IKSKMNIDVIVGNVVTEEATKELIENGADGIKVGIGPGSICTTRIVAGVGVPQITAIEKC 240

Query: 287 QSVRGR--IPVFIDSGVRRGTDVVKALALGADAVLIG 321
            SV  +  IP+  D G+R   D+ KALA+GA +V+IG
Sbjct: 241 SSVASKFGIPIIADGGIRYSGDIGKALAVGASSVMIG 277

emb|CAD98604.1| inosine-5'-monophosphate dehydrogenase, probable [Cryptosporidium parvum]
gb|AAL83208.1| inosine-5-monophosphate dehydrogenase [Cryptosporidium parvum]
(400 aa)

Score: 46 bits (110), Expect: 0.000849839
Length: 97, Idn/Pos/Gap = 33/50/7 (34%/51%/7%)

Query: 232 LKSITRLPILLKGVVTAEDAQRALQYGADGIWI-----SNHGARQLDGVTATIDCLEEVA 286
           +KS   + +++  VVT E  +  ++ GADGI +     S    R + GV        E  
Sbjct: 179 IKSKMNIDVIVGNVVTEEATKELIENGADGIKVGIGPGSICTTRIVAGVGVPQITAIEKC 238

Query: 287 QSVRGR--IPVFIDSGVRRGTDVVKALALGADAVLIG 321
            SV  +  IP+  D G+R   D+ KALA+GA +V+IG
Sbjct: 239 SSVASKFGIPIIADGGIRYSGDIGKALAVGASSVMIG 275

ref|ZP_00186807.2| COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Rubrobacter xylanophilus DSM 9941]
(359 aa)

Score: 46 bits (110), Expect: 0.00087138
Length: 185, Idn/Pos/Gap = 52/74/29 (28%/40%/15%)

Query: 207 AGASGLASYVASLIDASLNWNDIAWLKSITRL---------PILLKGVVTAEDAQRALQY 257
           +GA GL  ++ +L +A+    D  W     +L         P+++K V      + A   
Sbjct: 164 SGADGLCLHLNALQEAAQPGGDTDWSGIAEKLAAVAGELGVPVIVKEVGFGIGPRTARML 223

Query: 258 GADGIWISNHGAR----------------QLDGVTATIDCLEEVAQSVRGRIP---VFID 298
           G   +W  + G                   LD   A      E    VR   P   V   
Sbjct: 224 GGLPVWGVDVGGAGGTSWLEVEKRAWGRDDLDAFDAFGTPTAESISVVRKHCPDKLVIGS 283

Query: 299 SGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQK 358
            GVR G D VKALALGAD V   RP++   A + EE V R L   ++E +LA    G   
Sbjct: 284 GGVRTGVDAVKALALGADMVGAARPLLRP-ATESEEAVIRWLRRFREEMRLAAFCAGAPD 342

Query: 359 VSDIR 363
           ++ +R
Sbjct: 343 LNALR 347

ref|NP_578585.1| hypothetical protein PF0856 [Pyrococcus furiosus DSM 3638]
gb|AAL80980.1| hypothetical protein [Pyrococcus furiosus DSM 3638]
sp|Q8U2H9|IDI2_PYRFU Isopentenyl-diphosphate delta-isomerase (IPP isomerase) (Isopentenyl pyrophosphate isomerase)
(394 aa)

Score: 46 bits (110), Expect: 0.00103826
Length: 101, Idn/Pos/Gap = 32/52/4 (31%/51%/3%)

Query: 293 IPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQ 352
           +P+    G+R G  + KALA+GA  V I  P++   A    EGV +++    +E K AM 
Sbjct: 272 LPIIASGGMRDGITMAKALAMGASLVGIALPVLKPAAKGDVEGVIKVIKGYVEEIKNAMF 331

Query: 353 LCGCQKVSDIRRDLVVRDAFAPYDVRQMLS----VKMQSKL 389
           L G + V ++R+  +V   F    + Q +     VK ++KL
Sbjct: 332 LVGARNVEELRKVPIVFTGFVREWLEQRIDLQEFVKKRAKL 372

ref|ZP_00038799.1| COG0516: IMP dehydrogenase/GMP reductase [Xylella fastidiosa Dixon]
(485 aa)

Score: 46 bits (109), Expect: 0.00115721
Length: 100, Idn/Pos/Gap = 32/53/7 (32%/53%/7%)

Query: 229 IAWLKS-ITRLPILLKGVVTAEDAQRALQYGADGIWI-----SNHGARQLDGV-TATIDC 281
           +AW+K    +L ++   +VT + A   +  GAD + +     S    R + GV    I  
Sbjct: 260 VAWIKRYFPQLQVIGGNIVTGDAALALMDVGADAVKVGVGPGSICTTRMVAGVGVPQITA 319

Query: 282 LEEVAQSVRGRIPVFIDSGVRRGTDVVKALALGADAVLIG 321
           ++ V+ +++ RIP+  D G+R   D+ KALA GA  V+IG
Sbjct: 320 VQMVSDALQDRIPLIADGGIRYSGDIGKALAAGASTVMIG 359

ref|YP_056454.1| IMP dehydrogenase / GMP reductase [Propionibacterium acnes KPA171202]
gb|AAT83496.1| IMP dehydrogenase / GMP reductase [Propionibacterium acnes KPA171202]
(367 aa)

Score: 46 bits (109), Expect: 0.00117668
Length: 101, Idn/Pos/Gap = 31/55/14 (30%/54%/13%)

Query: 238 LPILLKGVVTAEDAQRALQYGADGIWI-----SNHGARQLDGVTATI-DCLEEVAQSVR- 290
           +P+++ G  T + A   ++ GA G+ +     + H  RQ+ G+  ++   + +VA++ R 
Sbjct: 187 VPVIVGGCATYQAALHLMRTGAAGVLVGFGGGATHTTRQVLGIQVSMASAIADVAEARRD 246

Query: 291 ------GR-IPVFIDSGVRRGTDVVKALALGADAVLIGRPI 324
                 GR + V  D  V R  D+ KA+A GADAV++G P+
Sbjct: 247 YMDESGGRYVHVIADGSVGRSGDIAKAIACGADAVMVGSPL 287

ref|NP_779643.1| inosine-5'-monophosphate dehydrogenase [Xylella fastidiosa Temecula1]
gb|AAO29292.1| inosine-5'-monophosphate dehydrogenase [Xylella fastidiosa Temecula1]
(485 aa)

Score: 46 bits (109), Expect: 0.00127907
Length: 100, Idn/Pos/Gap = 32/53/7 (32%/53%/7%)

Query: 229 IAWLKS-ITRLPILLKGVVTAEDAQRALQYGADGIWI-----SNHGARQLDGV-TATIDC 281
           +AW+K    +L ++   +VT + A   +  GAD + +     S    R + GV    I  
Sbjct: 260 VAWIKRYFPQLQVIGGNIVTGDAALALMDVGADAVKVGVGPGSICTTRMVAGVGVPQITA 319

Query: 282 LEEVAQSVRGRIPVFIDSGVRRGTDVVKALALGADAVLIG 321
           ++ V+ +++ RIP+  D G+R   D+ KALA GA  V+IG
Sbjct: 320 VQMVSDALQDRIPLIADGGIRYSGDIGKALAAGASTVMIG 359

ref|ZP_00040944.1| COG0516: IMP dehydrogenase/GMP reductase [Xylella fastidiosa Ann-1]
(485 aa)

Score: 46 bits (109), Expect: 0.00127907
Length: 100, Idn/Pos/Gap = 32/53/7 (32%/53%/7%)

Query: 229 IAWLKS-ITRLPILLKGVVTAEDAQRALQYGADGIWI-----SNHGARQLDGV-TATIDC 281
           +AW+K    +L ++   +VT + A   +  GAD + +     S    R + GV    I  
Sbjct: 260 VAWIKRYFPQLQVIGGNIVTGDAALALMDVGADAVKVGVGPGSICTTRMVAGVGVPQITA 319

Query: 282 LEEVAQSVRGRIPVFIDSGVRRGTDVVKALALGADAVLIG 321
           ++ V+ +++ RIP+  D G+R   D+ KALA GA  V+IG
Sbjct: 320 VQMVSDALQDRIPLIADGGIRYSGDIGKALAAGASTVMIG 359

gb|AAQ00183.1| IMP dehydrogenase/GMP reductase [Prochlorococcus marinus subsp. marinus str. CCMP1375]
ref|NP_875530.1| IMP dehydrogenase/GMP reductase [Prochlorococcus marinus subsp. marinus str. CCMP1375]
(387 aa)

Score: 46 bits (109), Expect: 0.00141377
Length: 116, Idn/Pos/Gap = 37/53/24 (31%/45%/20%)

Query: 238 LPILLKGVVTAEDAQRALQYGADGIWIS-NHGA----RQLDGV-----TATIDC---LEE 284
           +P+++   VT E A   ++ G  GI +    GA    R + GV     TA  DC    ++
Sbjct: 188 IPVIVGNCVTYEVALNLMRAGVSGILVGIGPGAACTSRGVLGVGVPQATAISDCSAARDD 247

Query: 285 VAQSVRGRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIV-----------WGLA 329
             +     +PV  D G+  G DV K +A GAD V+IG PI            WG+A
Sbjct: 248 YKKETGNHVPVIADGGIITGGDVCKCIACGADGVMIGSPIARASEAPGNGYHWGMA 303

ref|NP_299709.1| inosine-5'-monophosphate dehydrogenase [Xylella fastidiosa 9a5c]
gb|AAF85229.1| inosine-5'-monophosphate dehydrogenase [Xylella fastidiosa 9a5c]
pir||B82558 IMP dehydrogenase (EC 1.1.1.205) XF2430 [similarity] - Xylella fastidiosa (strain 9a5c)
(485 aa)

Score: 46 bits (108), Expect: 0.00151136
Length: 100, Idn/Pos/Gap = 32/53/7 (32%/53%/7%)

Query: 229 IAWLKS-ITRLPILLKGVVTAEDAQRALQYGADGIWI-----SNHGARQLDGV-TATIDC 281
           +AW+K    +L ++   +VT + A   +  GAD + +     S    R + GV    I  
Sbjct: 260 VAWIKRYFPQLQVIGGNIVTGDAALALMDAGADAVKVGVGPGSICTTRMVAGVGVPQITA 319

Query: 282 LEEVAQSVRGRIPVFIDSGVRRGTDVVKALALGADAVLIG 321
           ++ V+ +++ RIP+  D G+R   D+ KALA GA  V+IG
Sbjct: 320 VQMVSDALQDRIPLIADGGIRYSGDIGKALAAGASTVMIG 359

pdb|1VRD|B Chain B, Crystal Structure Of Inosine-5'-Monophosphate Dehydrogenase (Tm1347) From Thermotoga Maritima At 2.18 A Resolution
pdb|1VRD|A Chain A, Crystal Structure Of Inosine-5'-Monophosphate Dehydrogenase (Tm1347) From Thermotoga Maritima At 2.18 A Resolution
(494 aa)

Score: 46 bits (108), Expect: 0.00154967
Length: 111, Idn/Pos/Gap = 35/57/13 (31%/51%/11%)

Query: 238 LPILLKGVVTAEDAQRALQYGADGIWI-----SNHGARQLDGV-----TATIDCLEEVAQ 287
           LP++   V T E  +  ++ GAD + +     S    R + GV     TA ++C  EVA+
Sbjct: 279 LPVVAGNVATPEGTEALIKAGADAVKVGVGPGSICTTRVVAGVGVPQLTAVMEC-SEVAR 337

Query: 288 SVRGRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYR 338
             +  +P+  D G+R   D+VKALA GA++V++G          GE  +Y+
Sbjct: 338 --KYDVPIIADGGIRYSGDIVKALAAGAESVMVGSIFAGTEEAPGETILYQ 386

ref|NP_229148.1| inosine-5'-monophosphate dehydrogenase [Thermotoga maritima MSB8]
gb|AAD36418.1| inosine-5'-monophosphate dehydrogenase [Thermotoga maritima MSB8]
pir||C72264 IMP dehydrogenase (EC 1.1.1.205) - Thermotoga maritima  (strain MSB8)
(482 aa)

Score: 46 bits (108), Expect: 0.00154967
Length: 111, Idn/Pos/Gap = 35/57/13 (31%/51%/11%)

Query: 238 LPILLKGVVTAEDAQRALQYGADGIWI-----SNHGARQLDGV-----TATIDCLEEVAQ 287
           LP++   V T E  +  ++ GAD + +     S    R + GV     TA ++C  EVA+
Sbjct: 267 LPVVAGNVATPEGTEALIKAGADAVKVGVGPGSICTTRVVAGVGVPQLTAVMEC-SEVAR 325

Query: 288 SVRGRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYR 338
             +  +P+  D G+R   D+VKALA GA++V++G          GE  +Y+
Sbjct: 326 --KYDVPIIADGGIRYSGDIVKALAAGAESVMVGSIFAGTEEAPGETILYQ 374

gb|AAP77299.1| Inosinic acid dehydrogenase GuaB [Helicobacter hepaticus ATCC 51449]
ref|NP_860233.1| Inosinic acid dehydrogenase GuaB [Helicobacter hepaticus ATCC 51449]
(481 aa)

Score: 46 bits (108), Expect: 0.00156265
Length: 99, Idn/Pos/Gap = 32/53/11 (32%/53%/11%)

Query: 232 LKSITRLPILLKGVVTAEDAQRALQYGADGIWI-----SNHGARQLDGV----TATIDCL 282
           +KS   + I++  VVT +  Q  +  GAD + +     S    R + GV     + ID  
Sbjct: 260 IKSKLTIDIVVGNVVTPQATQDLINAGADAVKVGIGPGSICTTRIVAGVGMPQISAIDDC 319

Query: 283 EEVAQSVRGRIPVFIDSGVRRGTDVVKALALGADAVLIG 321
            ++AQ  + +IP+  D G++   D+ KALA+GA +V+IG
Sbjct: 320 SQIAQ--KHKIPIIADGGIKYSGDIAKALAVGASSVMIG 356

ref|NP_143100.1| hypothetical protein PH1202 [Pyrococcus horikoshii OT3]
dbj|BAA30302.1| 371aa long hypothetical protein [Pyrococcus horikoshii OT3]
sp|O58893|IDI2_PYRHO Isopentenyl-diphosphate delta-isomerase (IPP isomerase) (Isopentenyl pyrophosphate isomerase)
(371 aa)

Score: 46 bits (108), Expect: 0.00158895
Length: 357, Idn/Pos/Gap = 83/139/47 (23%/38%/13%)

Query:  42 EQTLRDNEEA-----FRRLRFRPRVL--IDVSRVDITKQVMGIDLSFPLMVAP-TAMQRM  93
           E  L+ N EA     F  + F  + L  ID   +D+T + +G    +P+M+   T   R 
Sbjct:  15 EHCLKRNVEAHVSNGFEDVYFVHKSLPEIDKDEIDLTVEFLGRKFDYPIMITGMTGGTRR  74

Query:  94 AHPEGEL--ATARAVARIGTVMGLSS----------WATTSLEDVAAHV-----PGLPKF 136
               G++    A A   +    G+ S          W +  + DVA  +      G P+F
Sbjct:  75 EEIAGKINRTLAMAAEELNIPFGVGSQRAMIEKPETWESYYVRDVAPDIFLIGNLGAPQF 134

Query: 137 FQLYVYKDRAITERLVRRAERAGFRAIALTVDTPQLG-RREADIRNQFQLPPHLSLANFA 195
            +    K R   + ++   E+    AIA+ ++  Q   + E D      L    +LA   
Sbjct: 135 GK--NAKKRYSVKEVLYAIEKIEADAIAIHMNPLQESVQPEGDTTYAGVLE---ALAEIK 189

Query: 196 DMKDFAQVKGGAGASGLASYVASLIDASLNWNDIAWLKSITRLPILLKGVVTAEDAQRAL 255
              ++  +    GA         L    ++  DI+ L   +   +       +E  + AL
Sbjct: 190 SSINYPVIAKETGAGVSKEVAIELESVGIDAIDISGLGGTSWSAVEYYRAKDSEKRKIAL 249

Query: 256 QYGADGIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALALGA 315
           ++   GI               T   L EV  +    +P+    G+R G  + KALA+GA
Sbjct: 250 KFWDWGI--------------KTAISLAEVRWATN--LPIIASGGMRDGVMMAKALAMGA 293

Query: 316 DAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLVVRDAF 372
             V I  P++   A    EGV R++    +E K  M L G + + ++RR  +V   F
Sbjct: 294 SLVGIALPVLRPAARGDVEGVVRIIRGYAEEIKNVMFLVGARNIRELRRVPLVITGF 350

ref|ZP_00151382.2| COG0516: IMP dehydrogenase/GMP reductase [Dechloromonas aromatica RCB]
(487 aa)

Score: 45 bits (107), Expect: 0.00223707
Length: 101, Idn/Pos/Gap = 30/56/8 (29%/55%/7%)

Query: 229 IAWLK-SITRLPILLKGVVTAEDAQRALQYGADGIWI-----SNHGARQLDGV-TATIDC 281
           + W+K +  ++ ++   + TA+ A+  +  GADG+ +     S    R + GV    I  
Sbjct: 260 VQWVKKNFPQIEVIGGNIATADAARALVDMGADGVKVGIGPGSICTTRIVAGVGVPQITA 319

Query: 282 LEEVAQSVRGR-IPVFIDSGVRRGTDVVKALALGADAVLIG 321
           ++ V+ S++G  +P+  D G+R   D+ KA+A GAD V++G
Sbjct: 320 IQNVSDSLKGTGVPMIADGGIRYSGDIAKAIAAGADTVMLG 360

ref|YP_200833.1| inosine-5'-monophosphate dehydrogenase [Xanthomonas oryzae pv. oryzae KACC10331]
gb|AAW75448.1| inosine-5'-monophosphate dehydrogenase [Xanthomonas oryzae pv. oryzae KACC10331]
(485 aa)

Score: 45 bits (106), Expect: 0.00302086
Length: 100, Idn/Pos/Gap = 31/54/7 (31%/54%/7%)

Query: 229 IAWLK-SITRLPILLKGVVTAEDAQRALQYGADGIWI-----SNHGARQLDGV-TATIDC 281
           +AW+K +  +L ++   +VT + A   +  GAD + +     S    R + GV    I  
Sbjct: 260 VAWVKKTYPQLQVIGGNIVTGDAALALMDAGADAVKVGVGPGSICTTRVVAGVGVPQITA 319

Query: 282 LEEVAQSVRGRIPVFIDSGVRRGTDVVKALALGADAVLIG 321
           ++ VA++++ RIP+  D G+R   D+ KAL  GA  V++G
Sbjct: 320 VDMVAEALQDRIPLIADGGIRYSGDIGKALVAGASTVMVG 359

gb|AAM37141.1| inosine-5'-monophosphate dehydrogenase [Xanthomonas axonopodis pv. citri str. 306]
ref|NP_642605.1| inosine-5'-monophosphate dehydrogenase [Xanthomonas axonopodis pv. citri str. 306]
(485 aa)

Score: 45 bits (106), Expect: 0.00312338
Length: 100, Idn/Pos/Gap = 31/54/7 (31%/54%/7%)

Query: 229 IAWLK-SITRLPILLKGVVTAEDAQRALQYGADGIWI-----SNHGARQLDGV-TATIDC 281
           +AW+K +  +L ++   +VT + A   +  GAD + +     S    R + GV    I  
Sbjct: 260 VAWVKKTYPQLQVIGGNIVTGDAALALMDAGADAVKVGVGPGSICTTRVVAGVGVPQITA 319

Query: 282 LEEVAQSVRGRIPVFIDSGVRRGTDVVKALALGADAVLIG 321
           ++ VA++++ RIP+  D G+R   D+ KAL  GA  V++G
Sbjct: 320 VDMVAEALQDRIPLIADGGIRYSGDIGKALVAGASTVMVG 359

ref|NP_688321.1| isopentenyl-diphosphate delta-isomerase [Streptococcus agalactiae 2603V/R]
gb|AAN00194.1| isopentenyl-diphosphate delta-isomerase [Streptococcus agalactiae 2603V/R]
(331 aa)

Score: 45 bits (105), Expect: 0.00414791
Length: 79, Idn/Pos/Gap = 23/45/0 (29%/56%/0%)

Query: 286 AQSVRGRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKD 345
           AQS+  ++ +    G+R   D+VK L LGA AV + R ++  +     + V  +L+  K+
Sbjct: 238 AQSMMDKMDILASGGIRHPLDMVKCLVLGAKAVGLSRTVLELVERYPVDDVIAILNSWKE 297

Query: 346 EFKLAMQLCGCQKVSDIRR 364
           + ++ M    C+K++D+R+
Sbjct: 298 DLRMIMCALNCKKITDLRQ 316

ref|NP_637540.1| inosine-5'-monophosphate dehydrogenase [Xanthomonas campestris pv. campestris str. ATCC 33913]
gb|AAM41464.1| inosine-5'-monophosphate dehydrogenase [Xanthomonas campestris pv. campestris str. ATCC 33913]
(485 aa)

Score: 44 bits (104), Expect: 0.00421771
Length: 100, Idn/Pos/Gap = 31/53/7 (31%/53%/7%)

Query: 229 IAWLK-SITRLPILLKGVVTAEDAQRALQYGADGIWI-----SNHGARQLDGV-TATIDC 281
           +AW+K +   L ++   +VT + A   +  GAD + +     S    R + GV    I  
Sbjct: 260 VAWVKKTYPHLQVIGGNIVTGDAALALMDAGADAVKVGVGPGSICTTRVVAGVGVPQITA 319

Query: 282 LEEVAQSVRGRIPVFIDSGVRRGTDVVKALALGADAVLIG 321
           ++ VA++++ RIP+  D G+R   D+ KAL  GA  V++G
Sbjct: 320 VDMVAEALQDRIPLIADGGIRYSGDIGKALVAGASTVMVG 359

emb|CAD47052.1| Unknown [Streptococcus agalactiae NEM316]
ref|NP_735830.1| hypothetical protein gbs1393 [Streptococcus agalactiae NEM316]
(331 aa)

Score: 44 bits (104), Expect: 0.00470093
Length: 79, Idn/Pos/Gap = 23/45/0 (29%/56%/0%)

Query: 286 AQSVRGRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKD 345
           AQS+  ++ +    G+R   D+VK L LGA AV + R ++  +     + V  +L+  K+
Sbjct: 238 AQSMMDKMDILASGGIRHPLDMVKCLVLGAKAVGLSRTVLELVERYPVDDVIAILNSWKE 297

Query: 346 EFKLAMQLCGCQKVSDIRR 364
           + ++ M    C+K++D+R+
Sbjct: 298 DLRMIMCALNCKKITDLRQ 316

ref|ZP_00166814.2| COG0516: IMP dehydrogenase/GMP reductase [Ralstonia eutropha JMP134]
(487 aa)

Score: 44 bits (104), Expect: 0.00474032
Length: 101, Idn/Pos/Gap = 35/54/8 (34%/53%/7%)

Query: 229 IAWLKSITRLPILLKGVVTAEDAQRAL-QYGADGIWI-----SNHGARQLDGV-TATIDC 281
           + W+K       ++ G +   DA RAL ++GADG+ +     S    R + GV    I  
Sbjct: 259 VRWVKQNFPQVQVVGGNIATGDAARALVEHGADGVKVGIGPGSICTTRIVAGVGVPQITA 318

Query: 282 LEEVAQSVRGR-IPVFIDSGVRRGTDVVKALALGADAVLIG 321
           +  VA++++G  +P+  D GVR   DV KALA GA  V++G
Sbjct: 319 VSNVAEALKGTGVPLIADGGVRYSGDVAKALAAGAHTVMMG 359

ref|NP_782942.1| inosine-5-monophosphate dehydrogenase [Clostridium tetani E88]
gb|AAO36879.1| inosine-5-monophosphate dehydrogenase [Clostridium tetani E88]
(484 aa)

Score: 44 bits (104), Expect: 0.00478003
Length: 132, Idn/Pos/Gap = 39/59/15 (29%/44%/11%)

Query: 238 LPILLKGVVTAEDAQRALQYGADGIWI-----SNHGARQLDGV-----TATIDCLEEVAQ 287
           L I+   V T E  +  +  GAD + +     S    R + GV     TA +DC+EE  +
Sbjct: 269 LQIIAGNVATPEATRDLILAGADCVKVGIGPGSICTTRVVAGVGVPQLTAVMDCVEEAQK 328

Query: 288 SVRGRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVY--RLLSLLKD 345
                +PV  D G++   D+VKALA GA   ++G  +       GE  +Y  R   + + 
Sbjct: 329 H---GVPVIADGGIKYSGDIVKALAAGASVCMMGSLLAGCAESPGETEIYQGRSYKVYRG 385

Query: 346 EFKLAMQLCGCQ 357
              LA   CG +
Sbjct: 386 MGSLASMACGSK 397

ref|NP_924549.1| IMP dehydrogenase [Gloeobacter violaceus PCC 7421]
dbj|BAC89544.1| IMP dehydrogenase [Gloeobacter violaceus PCC 7421]
(385 aa)

Score: 44 bits (104), Expect: 0.00486047
Length: 127, Idn/Pos/Gap = 40/59/26 (31%/46%/20%)

Query: 228 DIAWLKSITRLPILLKGVVTAEDAQRALQYGADGIWI-----SNHGARQLDGV-----TA 277
           D+A   +   +P++L  VVT E A   +Q GA  + +     +   +R + GV     TA
Sbjct: 176 DLAEFCAAMPIPVVLGNVVTYEVALDLMQAGAAAVLVGIGPGAACTSRGVLGVGIPQATA 235

Query: 278 TIDCL----EEVAQSVRGRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIV-------- 325
             DC     +  AQ+ R  +PV  D G+  G D+ K +A GAD V+IG P          
Sbjct: 236 VSDCAAARDDYFAQTGR-YVPVIADGGLVTGGDICKCIACGADGVMIGSPFARAAEAPGN 294

Query: 326 ---WGLA 329
              WG+A
Sbjct: 295 GFHWGMA 301

ref|ZP_00292007.1| COG0516: IMP dehydrogenase/GMP reductase [Thermobifida fusca]
(370 aa)

Score: 44 bits (104), Expect: 0.00506753
Length: 109, Idn/Pos/Gap = 34/54/14 (31%/49%/12%)

Query: 238 LPILLKGVVTAEDAQRALQYGADGIWI-----SNHGARQLDGVTATI-DCLEEVAQSVR- 290
           +P+++ G  T   A   ++ GA G+ +     S H  R + GV   +   + +VA + R 
Sbjct: 188 VPVVVGGCATYTAALHLMRTGAAGVLVGFGGGSGHTTRSVLGVAVPMATAIGDVAAARRD 247

Query: 291 ------GR-IPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDG 332
                 GR + V  D G+ R  D+ KALA GADAV++G P+   +   G
Sbjct: 248 YLDESGGRYVHVIADGGMTRSGDIAKALACGADAVMVGSPLARAVEAPG 296

dbj|BAC82424.1| isopentenyl diphosphate isomerase [Sulfolobus shibatae]
sp|P61615|IDI2_SULSH Isopentenyl-diphosphate delta-isomerase (IPP isomerase) (Isopentenyl pyrophosphate isomerase)
(368 aa)

Score: 44 bits (104), Expect: 0.00528342
Length: 108, Idn/Pos/Gap = 33/51/2 (30%/47%/1%)

Query: 261 GIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALALGADAVLI 320
           G W +      LD    T   + EV  SV     V    G+R G D  KA+ALGAD   +
Sbjct: 237 GNWKAESAKNFLDWGVPTAASIMEVRYSVPDSFLVG-SGGIRSGLDAAKAIALGADIAGM 295

Query: 321 GRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLVV 368
             P++   A++G+E + +    +  E K AM L G + V  +++  +V
Sbjct: 296 ALPVLKS-AIEGKESLEQFFRKIIFELKAAMMLTGSKDVDALKKTSIV 342

ref|NP_613835.1| Glutamate synthase subunit 2 [Methanopyrus kandleri AV19]
gb|AAM01765.1| Glutamate synthase subunit 2 [Methanopyrus kandleri AV19]
(429 aa)

Score: 44 bits (104), Expect: 0.00528342
Length: 112, Idn/Pos/Gap = 38/55/23 (33%/49%/20%)

Query: 229 IAWLKSIT--RLPILLK---GVVTAEDAQRALQYGADGIWI---------------SNHG 268
           I  L+ IT  ++PI++K   G V  ED + A + GAD I I                N G
Sbjct: 222 IEQLREITDWKIPIIVKYSPGRVK-EDVKIAAKAGADIIAIDGMQGGTGASPEIATENAG 280

Query: 269 ARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALALGADAVLI 320
              +  +   ++ L E+   +R  + + I  G+R G DV KALALGADAV +
Sbjct: 281 IPTIAALVQAVEALNEIG--MRDEVDIIISGGIRDGADVAKALALGADAVYV 330

dbj|BAB32625.1| isopentenyl diphosphate isomerase [Bacillus subtilis]
pdb|1P0N|B Chain B, Ipp:dmapp Isomerase Type Ii, Fmn Complex
pdb|1P0N|A Chain A, Ipp:dmapp Isomerase Type Ii, Fmn Complex
pdb|1P0K|B Chain B, Ipp:dmapp Isomerase Type Ii Apo Structure
pdb|1P0K|A Chain A, Ipp:dmapp Isomerase Type Ii Apo Structure
sp|P50740|IDI2_BACSU Isopentenyl-diphosphate delta-isomerase (IPP isomerase) (Isopentenyl pyrophosphate isomerase)
emb|CAG77478.1| isopentenyl diphosphate isomerase, type II [Bacillus subtilis]
(349 aa)

Score: 44 bits (104), Expect: 0.00541734
Length: 254, Idn/Pos/Gap = 55/105/40 (21%/41%/15%)

Query: 147 ITERLVRRAERAGFRAIALTVDTPQLGRREADIRNQFQL-----PPHLSLANFADMKDFA 201
           I + L R A +AG   I L V +     ++   R  +++     P  L  AN       A
Sbjct:  74 INKSLARAASQAG---IPLAVGSQMSALKDPSERLSYEIVRKENPNGLIFANLGSEATAA 130

Query: 202 QVKGGA---GASGLASYVASLIDASLNWNDIAWLKSITRL---------PILLKGV---V 246
           Q K      GA+ L  ++  + +  +   D ++  ++ R+         P+++K V   +
Sbjct: 131 QAKEAVEMIGANALQIHLNVIQEIVMPEGDRSFSGALKRIEQICSRVSVPVIVKEVGFGM 190

Query: 247 TAEDAQRALQYGADGIWISNHGARQLDGV-------------TATIDCLEEVAQSVRGRI 293
           +   A +  + GA  + I  +G      +             +  I     +A+ +R   
Sbjct: 191 SKASAGKLYEAGAAAVDIGGYGGTNFSKIENLRRQRQISFFNSWGISTAASLAE-IRSEF 249

Query: 294 P---VFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKDEFKLA 350
           P   +    G++   DV KA+ALGA    +    +  L   GEEG+   + L+ +E KL 
Sbjct: 250 PASTMIASGGLQDALDVAKAIALGASCTGMAGHFLKALTDSGEEGLLEEIQLILEELKLI 309

Query: 351 MQLCGCQKVSDIRR 364
           M + G + ++D+++
Sbjct: 310 MTVLGARTIADLQK 323

gb|AAB84700.1| glutamate synthase (NADPH), alpha subunit [Methanothermobacter thermautotrophicus str. Delta H]
ref|NP_275337.1| glutamate synthase (NADPH), alpha subunit [Methanothermobacter thermautotrophicus str. Delta H]
pir||E69123 glutamate synthase (NADPH), alpha subunit - Methanobacterium thermoautotrophicum (strain Delta H)
(499 aa)

Score: 44 bits (103), Expect: 0.00645479
Length: 112, Idn/Pos/Gap = 34/56/21 (30%/50%/18%)

Query: 229 IAWLKSIT--RLPILLKGVV--TAEDAQRALQYGADGIWI---------------SNHGA 269
           I+ L+ IT  ++PI++K      A+D + A + GAD + +                + G 
Sbjct: 291 ISQLREITDWKVPIMVKFTSGRVADDVKIAAKAGADAVVVDGMQGGTGAGPDVVTEHSGI 350

Query: 270 RQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALALGADAVLIG 321
             +  +    + L+EV  ++R  + +    G+R G DV KA+ALGADAV IG
Sbjct: 351 PTIAAIVEADEALKEV--NLRDEVSLIAAGGIRSGADVAKAIALGADAVYIG 400

ref|NP_893179.1| putative IMP dehydrogenase [Prochlorococcus marinus subsp. pastoris str. CCMP1986]
emb|CAE19521.1| putative IMP dehydrogenase [Prochlorococcus marinus subsp. pastoris str. CCMP1986]
(387 aa)

Score: 44 bits (103), Expect: 0.00645479
Length: 121, Idn/Pos/Gap = 38/54/32 (31%/44%/26%)

Query: 237 RLPILLKGVVTAEDAQRALQYGADGIWIS-NHGA----RQLDGV-----TATIDC----- 281
           ++P++    VT E A   ++ G  G+ +    GA    R + G+     TA  DC     
Sbjct: 187 KIPVVAGNCVTYEVADLLMKAGVAGLMVGIGPGAACTSRGVLGIGIPQATAISDCSSARD 246

Query: 282 --LEEVAQSVRGRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIV-----------WGL 328
              EE  + V    P+  D G+  G D+ K LA GADAV+IG PI            WG+
Sbjct: 247 DYFEETGRYV----PIIADGGIITGGDICKCLACGADAVMIGSPIAKSSSAPGNGFHWGM 302

Query: 329 A 329
           A
Sbjct: 303 A 303

ref|ZP_00178103.2| COG0516: IMP dehydrogenase/GMP reductase [Crocosphaera watsonii WH 8501]
(387 aa)

Score: 44 bits (103), Expect: 0.00650887
Length: 116, Idn/Pos/Gap = 39/54/24 (33%/46%/20%)

Query: 238 LPILLKGVVTAEDAQRALQYGADGIWIS-NHGA----RQLDGV-----TATIDCL--EEV 285
           +P++    VT E A   ++ GA  + +    GA    R + GV     TA  DC    + 
Sbjct: 188 MPVIFGNCVTYEVALNLMKAGAAALLVGIGPGAACTSRGVLGVGVPQPTAIADCAAARDD 247

Query: 286 AQSVRGR-IPVFIDSGVRRGTDVVKALALGADAVLIGRPIV-----------WGLA 329
            Q   GR +PV  D G+  G D+ K +A GADAV+IG PI            WG+A
Sbjct: 248 YQRETGRYVPVVADGGIVTGGDICKCIACGADAVMIGSPIARAAESPGRDYHWGMA 303

ref|ZP_00385572.1| COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Lactobacillus casei ATCC 334]
(106 aa)

Score: 44 bits (103), Expect: 0.00678616
Length: 75, Idn/Pos/Gap = 27/39/0 (36%/52%/0%)

Query: 10 ATQPLNLAEYHLFAKARLPAMVYGYYASGADDEQTLRDNEEAFRRLRFRPRVLIDVSRVD 69
          A   L+LA     A+  L    +GY + G+DD  T+R N  AF  ++  PRVL  V + D
Sbjct: 15 AIDVLDLASLEARAEKILGRGEFGYISEGSDDGYTMRRNTTAFTDVQMLPRVLQGVEKPD 74

Query: 70 ITKQVMGIDLSFPLM 84
           +   MG  L+ PL+
Sbjct: 75 QSTTFMGARLASPLL 89

ref|NP_441232.1| IMP dehydrogenase subunit [Synechocystis sp. PCC 6803]
dbj|BAA17912.1| IMP dehydrogenase subunit [Synechocystis sp. PCC 6803]
pir||S75050 IMP dehydrogenase homolog (EC 1.-.-.-) guaB - Synechocystis sp. (strain PCC 6803)
(387 aa)

Score: 44 bits (103), Expect: 0.00701647
Length: 116, Idn/Pos/Gap = 35/54/24 (30%/46%/20%)

Query: 238 LPILLKGVVTAEDAQRALQYGADGIWI-----SNHGARQLDGV-----TATIDCL---EE 284
           +P++L   VT E +   ++ GA  + +     +   +R + GV     TA  DC    ++
Sbjct: 188 MPVVLGNCVTYEVSLELMRAGAAAVLVGIGPGAACTSRGVLGVGVPQPTAIADCAAARDD 247

Query: 285 VAQSVRGRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIV-----------WGLA 329
             Q     +PV  D G+  G D+ K +A GADAV+IG PI            WG+A
Sbjct: 248 YLQETGRYVPVIADGGIITGGDICKCIACGADAVMIGSPIARAAEAPGRGFHWGMA 303

ref|ZP_00283648.1| COG0516: IMP dehydrogenase/GMP reductase [Burkholderia fungorum LB400]
(486 aa)

Score: 44 bits (103), Expect: 0.00713454
Length: 101, Idn/Pos/Gap = 34/58/8 (33%/57%/7%)

Query: 229 IAWLK-SITRLPILLKGVVTAEDAQRALQYGADGIWI-----SNHGARQLDGV-TATIDC 281
           + W+K +  R+ ++   + TA  A+  ++YGADG+ +     S    R + GV    +  
Sbjct: 259 VKWVKQNFPRVEVIGGNIATAAAAKALVEYGADGVKVGIGPGSICTTRIVAGVGVPQVTA 318

Query: 282 LEEVAQSVRGR-IPVFIDSGVRRGTDVVKALALGADAVLIG 321
           +  V+++++G  +PV  D GVR   DV KALA GA+AV++G
Sbjct: 319 ISNVSEALKGSGVPVIADGGVRFSGDVSKALAAGANAVMMG 359

sp|P21620|IMDH_LEIDO Inosine-5'-monophosphate dehydrogenase (IMP dehydrogenase) (IMPDH) (IMPD)
gb|AAA29253.1| IMP dehydrogenase
(514 aa)

Score: 43 bits (102), Expect: 0.00788587
Length: 102, Idn/Pos/Gap = 33/52/10 (32%/50%/9%)

Query: 229 IAWLKSI-TRLPILLKGVVTAEDAQRALQYGADGIWISNHGARQLDGVTATIDC------ 281
           I W+KS    L ++   VVT + A+  +  GADGI I   G+  +      + C      
Sbjct: 283 IKWVKSTYPHLEVVAGNVVTQDQAKNLIDAGADGIRIG-MGSGSICITQEVLACGRPQGT 341

Query: 282 -LEEVAQSVRGR-IPVFIDSGVRRGTDVVKALALGADAVLIG 321
            + +VAQ    R +P   D G+R+  D+ KALA+GA+  ++G
Sbjct: 342 AVYKVAQYCASRGVPCTADGGLRQVGDICKALAIGANCAMLG 383

ref|NP_968509.1| Isopentenyl-diphosphate delta-isomerase [Bdellovibrio bacteriovorus HD100]
emb|CAE79502.1| Isopentenyl-diphosphate delta-isomerase [Bdellovibrio bacteriovorus HD100]
(347 aa)

Score: 43 bits (102), Expect: 0.0086439
Length: 84, Idn/Pos/Gap = 25/46/1 (29%/54%/1%)

Query: 286 AQSVRGRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYRLLSLLKD 345
           A   R    ++   GVR G ++ K +ALGA  V + +P +   A+ G+E + +LL+ L+ 
Sbjct: 265 AIDARVEYQLWASGGVRNGLEIGKLMALGASKVGVAKPFLEA-ALQGDEALEKLLTQLET 323

Query: 346 EFKLAMQLCGCQKVSDIRRDLVVR 369
           E K+ M   G + + D++   V++
Sbjct: 324 ELKVTMFCTGSRNLKDLQSKKVIQ 347

ref|NP_577934.1| glutamate synthase subunit alpha [Pyrococcus furiosus DSM 3638]
gb|AAL80329.1| glutamate synthase subunit alpha; (NADPH) [Pyrococcus furiosus DSM 3638]
(502 aa)

Score: 43 bits (101), Expect: 0.0094748
Length: 106, Idn/Pos/Gap = 31/46/29 (29%/43%/27%)

Query: 287 QSVRGRIPVFIDSGVRRGTDVVKALALGADAVLIGRPIV-----------------WGLA 329
           + +R R+ + +  G+R   DVVKA+ALGADAV IG   +                 WG+ 
Sbjct: 371 EGIRNRVSLIVSGGIRNAADVVKAIALGADAVYIGTAALIAIGCTMCQKCYTGKCPWGIT 430

Query: 330 ---------VDGEEGVYRLLSLLKD---EFKLAMQLCGCQKVSDIR 363
                    +D  E   RL++LLK    E K  +   G   +  +R
Sbjct: 431 TQDPILSRRLDPNEASKRLINLLKAWSLEIKEMLGAMGINAIESLR 476

ref|ZP_00132545.2| COG0516: IMP dehydrogenase/GMP reductase [Haemophilus somnus 2336]
(487 aa)

Score: 43 bits (101), Expect: 0.00971496
Length: 108, Idn/Pos/Gap = 34/51/7 (31%/47%/6%)

Query: 238 LPILLKGVVTAEDAQRALQYGADGIWI-----SNHGARQLDGV-TATIDCLEEVAQSVRG 291
           LPI+   + TAE A      GA  + +     S    R + GV    I  + + A+++R 
Sbjct: 271 LPIIAGNIATAEGAIALADAGASAVKVGIGPGSICTTRIVTGVGVPQITAIADAAEALRE 330

Query: 292 R-IPVFIDSGVRRGTDVVKALALGADAVLIGRPIVWGLAVDGEEGVYR 338
           R IPV  D G+R   D+ KA+A GA  V++G          GE  +Y+
Sbjct: 331 RGIPVIADGGIRYSGDIAKAIAAGASCVMVGSMFAGTEEAPGEIELYQ 378

emb|CAA69539.1| orf c05008 [Sulfolobus solfataricus]
gb|AAK40424.1| FMN-dependent dehydrogenase, conserved hypothetical [Sulfolobus solfataricus P2]
ref|NP_341634.1| FMN-dependent dehydrogenase, conserved hypothetical [Sulfolobus solfataricus P2]
pir||S75425 hypothetical protein c05008 - Sulfolobus solfataricus
sp|P95997|IDI2_SULSO Isopentenyl-diphosphate delta-isomerase (IPP isomerase) (Isopentenyl pyrophosphate isomerase)
(368 aa)

Score: 43 bits (101), Expect: 0.0099612
Length: 108, Idn/Pos/Gap = 32/50/2 (29%/46%/1%)

Query: 261 GIWISNHGARQLDGVTATIDCLEEVAQSVRGRIPVFIDSGVRRGTDVVKALALGADAVLI 320
           G W +      LD    T   + EV  S+     V    G+R G D  KA+ALGAD   +
Sbjct: 237 GNWKAESAKNFLDWGVPTAASIIEVRYSIPDAFLVG-SGGIRSGLDAAKAIALGADIAGM 295

Query: 321 GRPIVWGLAVDGEEGVYRLLSLLKDEFKLAMQLCGCQKVSDIRRDLVV 368
             P++   A++G+E + +    +  E K  M L G + V  ++R  +V
Sbjct: 296 ALPVLKS-AIEGKESLEQFFRKIIFELKATMMLTGSKNVEALKRSSIV 342

Cyanidioschyzon merolae Genome Project