BLAST output

CMS112C (787 aa)
by blastp 2.2.10 [Oct-19-2004] against nr [Apr-30-2005] (XML result)


		orc1 [Schizosaccharomyces pombe]
		origin recognition protein Orc1+p
		origin recognition complex 1a protein [Arabidopsis thaliana]
		replication control protein 1 like [Arabidopsis thaliana]
		origin recognition complex 1 protein [Plasmodium yoelii yoelii]
		origin recognition complex 1 [Arabidopsis thaliana]
		origin recognition complex 1 protein [Plasmodium falciparum 3D7]
		origin recognition complex 1 protein, putative [Plasmodium berghei]
		Origin recognition complex, subunit 1-like [Danio rerio]
		origin recognition complex, subunit 1 [Rattus norvegicus]
		hypothetical protein [Gallus gallus]
		origin recognition complex subunit 1-like protein [Arabidopsis thaliana]
		PREDICTED: similar to origin recognition complex, subunit 1 [Canis familiaris]
		Origin recognition complex subunit 1 (Replication control protein 1)
		Origin recognition complex, subunit 1 [Homo sapiens]
		origin recognition complex, subunit 1-like (yeast) [Homo sapiens]
		origin recognition complex subunit 1 [Cricetulus griseus]
		XORC1 protein [Xenopus laevis]
		CG10667-PA [Drosophila melanogaster]
		origin recognition complex protein 1 [Xenopus laevis]
		origin recognition complex subunit 1 [Drosophila melanogaster]
		origin recognition complex, subunit 1 isoform B [Mus musculus]
		hypothetical protein DDB0218435 [Dictyostelium discoideum]
		PREDICTED: similar to origin recognition complex protein 1 [Gallus gallus]
		unnamed protein product [Mus musculus]
		origin recognition complex, subunit 1 isoform A [Mus musculus]
		Orc1l protein [Mus musculus]
		origin recognition complex subunit 1 [Bos taurus]
		unnamed protein product [Tetraodon nigroviridis]
		GA10479-PA [Drosophila pseudoobscura]
		putative origin recognition complex 1 [Oryza sativa (japonica cultivar-group)]
		similar to Origin recognition complex subunit 1 (DmORC1) [Apis mellifera]
		origin recognition complex subunit 1 [Zea mays]
		unnamed protein product [Yarrowia lipolytica CLIB99]
		origin recognition complex 1 [Oryza sativa (japonica cultivar-group)]
		ENSANGP00000011420 [Anopheles gambiae str. PEST]
		hypothetical protein FG01336.1 [Gibberella zeae PH-1]
		hypothetical protein AN1207.2 [Aspergillus nidulans FGSC A4]
		hypothetical protein MG05615.4 [Magnaporthe grisea 70-15]
		related to origin recognition protein Orc1p [Neurospora crassa]
		hypothetical protein CNBE3430 [Cryptococcus neoformans var. neoformans B-3501A]
		origin recognition complex subunit 1 homolog [MIPS] [Neurospora crassa]
		hypothetical protein CaO19.3000 [Candida albicans SC5314]
		unnamed protein product [Debaryomyces hansenii CBS767]
		hypothetical protein CaO19.10518 [Candida albicans SC5314]
		origin recognition complex 1 protein [Candida albicans]
		hypothetical protein UM06087.1 [Ustilago maydis 521]
		origin recognition complex 1 protein, putative [Plasmodium chabaudi]
		cell division control protein 6 [Strongylocentrotus purpuratus]
		PREDICTED: similar to origin recognition complex, subunit 1; origin recognition complex, subunit 1, S. cerevisiae, homolog-like; origin recognition complex 1; replication control protein 1; origin recognition complex, subunit 1 (yeast homolog)-like ... [Pan troglodytes]
		unnamed protein product [Candida glabrata CBS138]
		ORC1_KLULA [Kluyveromyces lactis NRRL Y-1140]
		KlORC1
		Hypothetical protein Y39A1A.12 [Caenorhabditis elegans]
		unnamed protein product [Saccharomyces cerevisiae]
		Hypothetical protein CBG18335 [Caenorhabditis briggsae]
		cell division cycle 6 [Cricetulus griseus]
		Cdc6-prov protein [Xenopus tropicalis]
		putative cdc6-2 protein [Arabidopsis thaliana]
		unknown [Schistosoma japonicum]
		cell division control protein 6 [validated] - African clawed frog
		Xcdc6 protein [Xenopus laevis]
		AER133Cp [Ashbya gossypii ATCC 10895]
		cell division control protein 6 [Eisenia fetida]
		PREDICTED: similar to Cell division control protein 6 homolog (CDC6-related protein) (p62(cdc6)) [Rattus norvegicus]
		LOC402825 protein [Danio rerio]
		probable CDC6 protein [imported] - Arabidopsis thaliana
		putative cell division control protein 6 [Oryza sativa (japonica cultivar-group)]
		cell division cycle 6 homolog [Mus musculus]
		putative CDC6 [Arabidopsis thaliana]
		unnamed protein product [Mus musculus]
		Cdc6 protein [Mus musculus]
		Cdc6-related protein [Xenopus laevis]
		CDC6 homolog [Homo sapiens]
		CDC6 cell division cycle 6 homolog (S. cerevisiae) [Homo sapiens]
		putative cell division control protein 6 [Oryza sativa (japonica cultivar-group)]
		PREDICTED: similar to CDC6 homolog [Canis familiaris]
		cdc18 [Schizosaccharomyces pombe]
		ENSANGP00000015641 [Anopheles gambiae str. PEST]
		PREDICTED: similar to CDC6 homolog, partial [Bos taurus]
		Cdc6-related protein [Xenopus laevis]
		Cdc6B protein [Xenopus laevis]
		CDC6 protein [Candida albicans]
		hypothetical protein CaO19.12707 [Candida albicans SC5314]
		ORC/CDC6 like AAA+ ATpase [Cryptosporidium parvum]
		hypothetical protein MG01614.4 [Magnaporthe grisea 70-15]
		putative CDC6 [Oryza sativa (japonica cultivar-group)]
		unnamed protein product [Tetraodon nigroviridis]
		hypothetical protein FG01030.1 [Gibberella zeae PH-1]
		putative CDC6 protein [Arabidopsis thaliana]
		cell division control protein 6 [Arabidopsis thaliana]
		unnamed protein product [Candida glabrata CBS138]
		hypothetical protein [Neurospora crassa]
		unnamed protein product [Debaryomyces hansenii CBS767]
		PREDICTED: similar to CDC6 homolog; CDC18 (cell division cycle 18, S.pombe, homolog)-like; CDC6-related protein; CDC6 (cell division cycle 6, S. cerevisiae) homolog [Pan troglodytes]
		hypothetical protein [imported] - Arabidopsis thaliana
		hypothetical protein UM03496.1 [Ustilago maydis 521]
		CG5971-PA [Drosophila melanogaster]
		GA19269-PA [Drosophila pseudoobscura]
		hypothetical cell division control protein 6 [Sulfolobus tokodaii str. 7]
		hypothetical protein CaO19.5242 [Candida albicans SC5314]
		hypothetical protein DDB0203551 [Dictyostelium discoideum]
		ORIGIN RECOGNITION COMPLEX SUBUNIT 1 [Encephalitozoon cuniculi GB-M1]
		cell division control protein 6, putative [Archaeoglobus fulgidus DSM 4304]
		unnamed protein product [Kluyveromyces lactis NRRL Y-1140]
		Cell division control protein 6 homolog (CDC6 homolog)
		cell division cycle protein [Saccharomyces cerevisiae]
		Cell division cycle related protein 6 [Caenorhabditis elegans]
		DNA polymerase II [Aeropyrum pernix K1]
		hypothetical protein AN5676.2 [Aspergillus nidulans FGSC A4]
		CDC6 protein
		unnamed protein product [Yarrowia lipolytica CLIB99]
		Cell division control 6/orc1 protein homolog (cdc6-1) [Sulfolobus solfataricus P2]
		COG1474: Cdc6-related protein, AAA superfamily ATPase [Methanococcoides burtonii DSM 6242]
		Hypothetical protein CBG12183 [Caenorhabditis briggsae]
		hypothetical protein PH0124 [Pyrococcus horikoshii OT3]
		Cell division control protein 6 homolog (CDC6 homolog)
		Cdc6/orc1 cell division control protein 6 [Pyrococcus abyssi GE5]
		unnamed protein product [Saccharomyces cerevisiae]
		Cell division control protein 6 homolog (CDC6 homolog)
		cell division control protein 6 homolog [Thermococcus kodakaraensis KOD1]
		origin recognition protein subunit 1 [Pyrococcus furiosus DSM 3638]
		cell division cycle protein [Nicotiana tabacum]
		GLP_49_8463_9581 [Giardia lamblia ATCC 50803]
		COG1474: Cdc6-related protein, AAA superfamily ATPase [Methanosarcina barkeri str. fusaro]
		AFR621Cp [Ashbya gossypii ATCC 10895]
		Cdc6 related protein [Methanothermobacter thermautotrophicus str. Delta H]
		origin recognition complex subunit [Methanosarcina mazei Go1]
		Cell division control protein 6 homolog 5 (CDC6 homolog 5)
		Orc7 [Halobacterium sp. NRC-1]
		Orc5 [Halobacterium sp. NRC-1]
		Cell division control protein 6 homolog 1 (CDC6 homolog 1)
		cell division control protein 6 [Methanosarcina acetivorans C2A]
		cell division control protein 6-like [Haloarcula marismortui ATCC 43049]
		hypothetical protein Chro.70263 [Cryptosporidium hominis]
		ORC/CDC6 like AAA ATpase [Cryptosporidium parvum]
		origin recognition complex subunit [Picrophilus torridus DSM 9790]
		cell division control protein 6 [Haloarcula marismortui ATCC 43049]
		Orc4 [Halobacterium sp. NRC-1]
		hypothetical protein 224.t00013 [Entamoeba histolytica HM-1:IMSS]
		origin recognition complex protein 1 [Thermoplasma volcanium GSS1]
		ATPase (AAA superfamily) [Thermoplasma volcanium GSS1]
		unnamed protein product [Methanothermobacter thermautotrophicus]
		probable DNA polymerase II (DP2), subunit 1 [Thermoplasma acidophilum DSM 1728]
		unnamed protein product [Methanothermobacter thermautotrophicus]
		hypothetical protein VNG0045C [Halobacterium sp. NRC-1]
		Cell division control protein 6 homolog 1 (CDC6 homolog 1)
		cell division control protein 6 homolog 6 [Haloarcula marismortui ATCC 43049]
		Cell division control 6/orc1 protein homolog (cdc6-3) [Sulfolobus solfataricus P2]
		hypothetical protein CNBJ2200 [Cryptococcus neoformans var. neoformans B-3501A]
		hypothetical protein ST2165 [Sulfolobus tokodaii str. 7]
		origin recognition complex subunit 4-like [Oryza sativa (japonica cultivar-group)]
		origin recognition complex 4 [Oryza sativa (japonica cultivar-group)]
		COG1474: Cdc6-related protein, AAA superfamily ATPase [Methanosarcina barkeri str. fusaro]
		cell division control protein 6 [Haloarcula marismortui ATCC 43049]
		ES43 like protein [Arabidopsis thaliana]
		Cell division control protein 6 homolog 10 (CDC6 homolog 10)
		P0445E10.5 [Oryza sativa (japonica cultivar-group)]
		Zgc:85772 [Danio rerio]
		cell division control protein 6 homolog 1 [Haloarcula marismortui ATCC 43049]
		putative ES43 protein [Arabidopsis thaliana]
		ES43 like protein [Arabidopsis thaliana]
		unnamed protein product [Yarrowia lipolytica CLIB99]
		Origin recognition complex, subunit 4-like [Xenopus tropicalis]
		origin recognition complex subunit 4 [Xenopus laevis]
		origin recognition complex 4 subunit [Arabidopsis thaliana]
		putative origin recognition complex subunit 4 [Arabidopsis thaliana]
		COG1474: Cdc6-related protein, AAA superfamily ATPase [Ferroplasma acidarmanus]
		hypothetical protein AN5892.2 [Aspergillus nidulans FGSC A4]
		putative DNA-binding protein [Oryza sativa (japonica cultivar-group)]
		hypothetical protein AF0695 [Archaeoglobus fulgidus DSM 4304]
		origin recognition complex subunit 4 [Zea mays]
		cell division control protein 6 [Haloarcula marismortui ATCC 43049]
		origin recognition complex protein 4 [Arabidopsis thaliana]
		putative ES43 protein [Oryza sativa (japonica cultivar-group)]
		Cell division control protein 6 homolog 1 (CDC6 homolog 1)
		cell division control protein 6 homolog 6 [Haloarcula marismortui ATCC 43049]
		Orc2 [Halobacterium sp. NRC-1]

emb|CAA22443.1| orc1 [Schizosaccharomyces pombe]
sp|P54789|ORC1_SCHPO Origin recognition complex subunit 1
gb|AAC49141.1| orc1+ protein
gb|AAC49129.1| Orp1
ref|NP_596060.1| origin recognition complex protein, subunit 1. [Schizosaccharomyces pombe]
(707 aa)

Score: 190 bits (483), Expect: 1.34712e-46
Length: 416, Idn/Pos/Gap = 145/208/64 (34%/50%/15%)

Query: 264 EQVDLHD----TGDEDAWDPAEERALQLRLRSRQRAAAGRSRGNNCSQESDMTPRPRAGG 319
           E  DL D    + D     P   R    R R      A   + N   Q   +TP P    
Sbjct: 253 ENFDLQDDSESSEDNLTIQPQTPRRRHKRSRHNSSNLASTPKRNGYKQPLQITPLPIR-- 310

Query: 320 QLLLWPSDVGAHEHRQSRISKNAVEFAEVSEPTGSVPRLLQVSRFGAPRVQLVCRDVETE 379
             +L   +     HR++R   +            SVP  LQ            CRD E  
Sbjct: 311 --MLSLEEFQGSPHRKARAMLH----------VASVPSTLQ------------CRDNEFS 346

Query: 380 RVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHFQYIEINGMT 439
            +   L   +   +  CLYISG PGTGKTA V   +  L++  ++GQ+P F + EINGM 
Sbjct: 347 TIFSNLESAIEEETGACLYISGTPGTGKTATVHEVIWNLQELSREGQLPEFSFCEINGMR 406

Query: 440 IPDPTRAYNILLQRL-GHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHNRKHHSSILV 498
           +    +AY+IL + L G R T          P  A  LLD RF      H   + SS +V
Sbjct: 407 VTSANQAYSILWESLTGERVT----------PIHAMDLLDNRF-----THASPNRSSCVV 451

Query: 499 LLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLLP-RLASRLGM 557
           L+DE+D LV ++    Q+VLY+F +W S P S L+++ +ANT+DLPER+L  R++SRLG+
Sbjct: 452 LMDELDQLVTHN----QKVLYNFFNWPSLPHSRLIVVAVANTMDLPERILSNRISSRLGL 507

Query: 558 NRQVFKPYSVTQLQQILRHKL-GPQLLQHFDEDALELCTRRVAAVSGDIRRALAICLHAY 616
           +R  F+PY+ TQL+ I+  +L   +    F  DA+    R+VAAVSGD RRAL IC    
Sbjct: 508 SRVPFEPYTHTQLEIIIAARLEAVRDDDVFSSDAIRFAARKVAAVSGDARRALDIC---- 563

Query: 617 ARSHSEDCSLRASENEHDRLVSAVDIDEAIRELTPSSVQSAVKQLSQIEQQVLMSA 672
            R  SE      +EN++ ++   + I +AI E+T S +Q  ++ LS + Q+V + A
Sbjct: 564 -RRASE-----LAENKNGKVTPGL-IHQAISEMTASPLQKVLRNLSFM-QKVFLCA 611

gb|AAB38247.1| origin recognition protein Orc1+p
(544 aa)

Score: 187 bits (476), Expect: 8.65921e-46
Length: 416, Idn/Pos/Gap = 145/208/64 (34%/50%/15%)

Query: 264 EQVDLHD----TGDEDAWDPAEERALQLRLRSRQRAAAGRSRGNNCSQESDMTPRPRAGG 319
           E  DL D    + D     P   R    R R      A   + N   Q   +TP P    
Sbjct:  90 ENFDLQDDSESSEDNLTIQPQTPRRRHKRSRHNSSNLASTPKRNGYKQPLQITPLPIR-- 147

Query: 320 QLLLWPSDVGAHEHRQSRISKNAVEFAEVSEPTGSVPRLLQVSRFGAPRVQLVCRDVETE 379
             +L   +     HR++R   +            SVP  LQ            CRD E  
Sbjct: 148 --MLSLEEFQGSPHRKARAMLH----------VASVPSTLQ------------CRDNEFS 183

Query: 380 RVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHFQYIEINGMT 439
            +   L   +   +  CLYISG PGTGKTA V   +  L++  ++GQ+P F + EINGM 
Sbjct: 184 TIFSNLESAIEEETGACLYISGTPGTGKTATVHEVIWNLQELSREGQLPEFSFCEINGMR 243

Query: 440 IPDPTRAYNILLQRL-GHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHNRKHHSSILV 498
           +    +AY+IL + L G R T          P  A  LLD RF      H   + SS +V
Sbjct: 244 VTSANQAYSILWESLTGERVT----------PIHAMDLLDNRF-----THASPNRSSCVV 288

Query: 499 LLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLLP-RLASRLGM 557
           L+DE+D LV ++    Q+VLY+F +W S P S L+++ +ANT+DLPER+L  R++SRLG+
Sbjct: 289 LMDELDQLVTHN----QKVLYNFFNWPSLPHSRLIVVAVANTMDLPERILSNRISSRLGL 344

Query: 558 NRQVFKPYSVTQLQQILRHKL-GPQLLQHFDEDALELCTRRVAAVSGDIRRALAICLHAY 616
           +R  F+PY+ TQL+ I+  +L   +    F  DA+    R+VAAVSGD RRAL IC    
Sbjct: 345 SRVPFEPYTHTQLEIIIAARLEAVRDDDVFSSDAIRFAARKVAAVSGDARRALDIC---- 400

Query: 617 ARSHSEDCSLRASENEHDRLVSAVDIDEAIRELTPSSVQSAVKQLSQIEQQVLMSA 672
            R  SE      +EN++ ++   + I +AI E+T S +Q  ++ LS + Q+V + A
Sbjct: 401 -RRASE-----LAENKNGKVTPGL-IHQAISEMTASPLQKVLRNLSFM-QKVFLCA 448

emb|CAD13174.1| origin recognition complex 1a protein [Arabidopsis thaliana]
ref|NP_567440.1| replication control protein, putative [Arabidopsis thaliana]
(809 aa)

Score: 183 bits (464), Expect: 2.11512e-44
Length: 553, Idn/Pos/Gap = 159/262/85 (28%/47%/15%)

Query: 258 NDGD----CAEQVDLH----------DTGDEDA---WDPAEERALQLRLRSRQRAAAGRS 300
           NDGD    C  + D+H            GDED+   W+  +E  +       +       
Sbjct: 318 NDGDDVFLCEYEYDVHWGSFKRVAELADGDEDSDQEWNGRKEEEIDYSDEEIEFDDEESV 377

Query: 301 RGNNCSQESDMTPRP-RAGGQLLLWPSDVGAHE--HRQSRISKNAVEFAEVSEPTGSVPR 357
           RG + S+      R  R  G   +    +  H   H+QS + K        + P  S+P 
Sbjct: 378 RGVSKSKRGGANSRKGRFFGLEKVGMKRIPEHVRCHKQSELEKAKATLLLATRPK-SLP- 435

Query: 358 LLQVSRFGAPRVQLVCRDVETERVLKFLTDCLRGSS--ERCLYISGVPGTGKTAVVRCAV 415
                          CR  E E +  F+   +       RC+YI GVPGTGKT  V   +
Sbjct: 436 ---------------CRSKEMEEITAFIKGSISDDQCLGRCMYIHGVPGTGKTISVLSVM 480

Query: 416 QQLEQRRQQGQVPHFQYIEINGMTIPDPTRAYNILLQRL-GHRSTGAAGGRRPPAPAEAA 474
           + L+   + G V  + ++EING+ +  P   Y+++ + L GHR     G ++      A 
Sbjct: 481 KNLKAEVEAGSVSPYCFVEINGLKLASPENIYSVIYEGLSGHR----VGWKK------AL 530

Query: 475 RLLDQRFRQRRGVHNRKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVI 534
           + L++RF + + +  +++    ++L+DE+D LV  +    Q VLY+ LDW ++P S+LV+
Sbjct: 531 QSLNERFAEGKKI-GKENEKPCILLIDELDVLVTRN----QSVLYNILDWPTKPNSKLVV 585

Query: 535 IGIANTLDLPERLLPRLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQHFDEDALELC 594
           +GIANT+DLPE+LLPR++SR+G+ R  F PY+  QLQ+I+  +L  + +  F++ A+E  
Sbjct: 586 LGIANTMDLPEKLLPRISSRMGIQRLCFGPYNHRQLQEIISTRL--EGINAFEKTAIEFA 643

Query: 595 TRRVAAVSGDIRRALAICLHAYARSHSEDCSLRASE-NEHDRLVSAVDIDEAIRELTPSS 653
           +R+VAA+SGD RRAL IC  A   +   D  L+ S  +   +LV   D++ AI+E+  + 
Sbjct: 644 SRKVAAISGDARRALEICRRA---AEVADYRLKKSNISAKSQLVIMADVEVAIQEMFQAP 700

Query: 654 VQSAVKQLSQIEQQVLMSAALCGRQAVQQGSETFRFQQIWHRFRQFHASTEGHPAYPLPL 713
               +K +S++  ++ ++A +   +  + G     F ++          T G  A+P   
Sbjct: 701 HIQVMKSVSKL-SRIFLTAMV--HELYKTGMAETSFDRVATTVSSI-CLTNGE-AFP--- 752

Query: 714 QDQIEEVWHILMGLCACNLLSCSVPSSSCAYAGFASTRLPNLHESQFVLNPLFDDIAFAF 773
                  W IL+ +  C+L  C +             RL  L      LN   DD+AFA 
Sbjct: 753 ------GWDILLKI-GCDLGECRIVLCEPG----EKHRLQKLQ-----LNFPSDDVAFAL 796

Query: 774 RENRSFAQAAGEL 786
           ++N+     A  L
Sbjct: 797 KDNKDLPWLANYL 809

emb|CAB10249.1| replication control protein 1 like [Arabidopsis thaliana]
emb|CAB78512.1| replication control protein 1 like [Arabidopsis thaliana]
pir||G71409 probable replication control protein - Arabidopsis thaliana
(771 aa)

Score: 182 bits (463), Expect: 2.58406e-44
Length: 553, Idn/Pos/Gap = 159/262/85 (28%/47%/15%)

Query: 258 NDGD----CAEQVDLH----------DTGDEDA---WDPAEERALQLRLRSRQRAAAGRS 300
           NDGD    C  + D+H            GDED+   W+  +E  +       +       
Sbjct: 280 NDGDDVFLCEYEYDVHWGSFKRVAELADGDEDSDQEWNGRKEEEIDYSDEEIEFDDEESV 339

Query: 301 RGNNCSQESDMTPRP-RAGGQLLLWPSDVGAHE--HRQSRISKNAVEFAEVSEPTGSVPR 357
           RG + S+      R  R  G   +    +  H   H+QS + K        + P  S+P 
Sbjct: 340 RGVSKSKRGGANSRKGRFFGLEKVGMKRIPEHVRCHKQSELEKAKATLLLATRPK-SLP- 397

Query: 358 LLQVSRFGAPRVQLVCRDVETERVLKFLTDCLRGSS--ERCLYISGVPGTGKTAVVRCAV 415
                          CR  E E +  F+   +       RC+YI GVPGTGKT  V   +
Sbjct: 398 ---------------CRSKEMEEITAFIKGSISDDQCLGRCMYIHGVPGTGKTISVLSVM 442

Query: 416 QQLEQRRQQGQVPHFQYIEINGMTIPDPTRAYNILLQRL-GHRSTGAAGGRRPPAPAEAA 474
           + L+   + G V  + ++EING+ +  P   Y+++ + L GHR     G ++      A 
Sbjct: 443 KNLKAEVEAGSVSPYCFVEINGLKLASPENIYSVIYEGLSGHR----VGWKK------AL 492

Query: 475 RLLDQRFRQRRGVHNRKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVI 534
           + L++RF + + +  +++    ++L+DE+D LV  +    Q VLY+ LDW ++P S+LV+
Sbjct: 493 QSLNERFAEGKKI-GKENEKPCILLIDELDVLVTRN----QSVLYNILDWPTKPNSKLVV 547

Query: 535 IGIANTLDLPERLLPRLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQHFDEDALELC 594
           +GIANT+DLPE+LLPR++SR+G+ R  F PY+  QLQ+I+  +L  + +  F++ A+E  
Sbjct: 548 LGIANTMDLPEKLLPRISSRMGIQRLCFGPYNHRQLQEIISTRL--EGINAFEKTAIEFA 605

Query: 595 TRRVAAVSGDIRRALAICLHAYARSHSEDCSLRASE-NEHDRLVSAVDIDEAIRELTPSS 653
           +R+VAA+SGD RRAL IC  A   +   D  L+ S  +   +LV   D++ AI+E+  + 
Sbjct: 606 SRKVAAISGDARRALEICRRA---AEVADYRLKKSNISAKSQLVIMADVEVAIQEMFQAP 662

Query: 654 VQSAVKQLSQIEQQVLMSAALCGRQAVQQGSETFRFQQIWHRFRQFHASTEGHPAYPLPL 713
               +K +S++  ++ ++A +   +  + G     F ++          T G  A+P   
Sbjct: 663 HIQVMKSVSKL-SRIFLTAMV--HELYKTGMAETSFDRVATTVSSI-CLTNGE-AFP--- 714

Query: 714 QDQIEEVWHILMGLCACNLLSCSVPSSSCAYAGFASTRLPNLHESQFVLNPLFDDIAFAF 773
                  W IL+ +  C+L  C +             RL  L      LN   DD+AFA 
Sbjct: 715 ------GWDILLKI-GCDLGECRIVLCEPG----EKHRLQKLQ-----LNFPSDDVAFAL 758

Query: 774 RENRSFAQAAGEL 786
           ++N+     A  L
Sbjct: 759 KDNKDLPWLANYL 771

gb|EAA17284.1| origin recognition complex 1 protein [Plasmodium yoelii yoelii]
(1049 aa)

Score: 181 bits (460), Expect: 5.43008e-44
Length: 316, Idn/Pos/Gap = 108/174/36 (34%/55%/11%)

Query: 348 VSEPTGSVPRLLQVSRFGAPRVQLVCRDVETERVLKFLTDCLRGS-SERCLYISGVPGTG 406
           ++ PT    R++Q+     P+  L CR+ E + V  FL   ++ S S + LYISG+PGTG
Sbjct: 624 ITHPTDRAIRMMQLDV--VPKY-LPCREKEIKEVHGFLESGIKQSGSNQILYISGMPGTG 680

Query: 407 KTAVVRCAVQQLEQRRQQGQVPHFQYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRR 466
           KTA V   +Q L+ +  +  +P F   EINGM +  P  AY +  ++L +         +
Sbjct: 681 KTATVYSVIQLLKNKSNKKLLPPFNVYEINGMNVVHPNAAYQVFYKQLFNS--------K 732

Query: 467 PPAPAEAARLLDQRFRQRRGVHNRKHHSSILVLL-DEMDALVLNHSAAAQRVLYDFLDWA 525
           PP    + +++D+ F +     N+K + ++ +L+ DE+D L+       Q+VL+   DW 
Sbjct: 733 PPNALSSFKIIDRLFNK-----NKKDNRNVSILIIDEIDYLI----TKTQKVLFTLFDWP 783

Query: 526 SRPASELVIIGIANTLDLPERLLPRLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQH 585
           ++  S+L++I I+NT+DLPERL+PR  SRL   R VF PY   ++++I++ +L       
Sbjct: 784 TKVNSKLILIAISNTMDLPERLIPRCRSRLAFGRLVFSPYKGDEIEKIIKERLN-NCKDI 842

Query: 586 FDEDALELCTRRVAAVSGDIRRALAICLHAYARSHSEDCSLRASENEHDRLVSAVDIDEA 645
            D  A++LC R+VA VSGDIR+AL IC  A+             EN+  + +   DI EA
Sbjct: 843 IDHTAIQLCARKVANVSGDIRKALQICRKAF-------------ENKRGQKIVPRDIIEA 889

Query: 646 IRELTPSSVQSAVKQL 661
             +L  S + +A+  L
Sbjct: 890 TNQLFDSPLTNAINYL 905

gb|AAK69447.1| origin recognition complex 1 [Arabidopsis thaliana]
(809 aa)

Score: 181 bits (460), Expect: 5.66141e-44
Length: 544, Idn/Pos/Gap = 160/268/81 (29%/49%/14%)

Query: 258 NDGD----CAEQVDLH----------DTGDEDA---WDPAEERALQLRLRSRQRAAAGRS 300
           NDGD    C  + D+H            GDED+   W+  +E  +       +       
Sbjct: 318 NDGDDVFLCEYEYDVHWGSFKRVAELADGDEDSDQEWNGRKEEEIDYSDEEIEFDDEESV 377

Query: 301 RGNNCSQESDMTPRPRAGGQLLLWPSDVGAHEHRQSRISKNAVEFAEVSEPTGSVPRLLQ 360
           RG + S+      R    G+        G  +    RI ++ V   + SE   +   LL 
Sbjct: 378 RGVSKSKRGGANSRK---GRFF------GVEKVGMKRIPEH-VRCHKQSELEKAKATLLL 427

Query: 361 VSRFGAPRVQLVCRDVETERVLKFLTDCLRGSS--ERCLYISGVPGTGKTAVVRCAVQQL 418
            +R   P+  L CR  E E +  F+   +       RC+YI GVPGTGKT  V   ++ L
Sbjct: 428 ATR---PK-SLPCRSKEMEEITAFIKGSISDDQCLGRCMYIHGVPGTGKTISVLSVMKNL 483

Query: 419 EQRRQQGQVPHFQYIEINGMTIPDPTRAYNILLQRL-GHRSTGAAGGRRPPAPAEAARLL 477
           +   + G V  + ++EING+ +  P   Y+++ + L GHR     G ++      A + L
Sbjct: 484 KAEVEAGSVSPYCFVEINGLKLASPENIYSVIYEGLSGHR----VGWKK------ALQSL 533

Query: 478 DQRFRQRRGVHNRKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGI 537
           ++RF + + +  +++    ++L+DE+D LV  +    Q VLY+ LDW ++P S+LV++GI
Sbjct: 534 NERFAEGKKI-GKENEKPCILLIDELDVLVTRN----QSVLYNILDWPTKPNSKLVVLGI 588

Query: 538 ANTLDLPERLLPRLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQHFDEDALELCTRR 597
           ANT+DLPE LLPR++SR+G+ R  F PY+  QLQ+I+  +L  + +  F++ A+E  +R+
Sbjct: 589 ANTMDLPEMLLPRISSRMGIQRLCFGPYNHRQLQEIISTRL--EGINAFEKTAIEFASRK 646

Query: 598 VAAVSGDIRRALAICLHAYARSHSEDCSLRASE-NEHDRLVSAVDIDEAIRELTPSSVQS 656
           VAA+SGD RRAL IC  A   +   D  L+ S  +   +LV   D++ AI+E+  +    
Sbjct: 647 VAAISGDARRALEICRRA---AEVADYRLKKSNISAKSQLVIMADVEVAIQEMFQAPHIQ 703

Query: 657 AVKQLSQIEQQVLMSAALCGRQAVQQGSETFRFQQIWHRFRQFHASTEGHPAYPLPLQD- 715
            +K +S++  ++ ++A +   +  + G     F ++        A+T      P+ L + 
Sbjct: 704 VMKSVSKL-SRIFLTAMV--HELYKTGMAETSFDRV--------ATT----VSPICLTNG 748

Query: 716 QIEEVWHILMGLCACNLLSCSVPSSSCAYAGFASTRLPNLHESQFVLNPLFDDIAFAFRE 775
           +    W IL+ +  C+L  C +  + C        RL  L      LN   DD+AFA ++
Sbjct: 749 EAFPGWDILLKI-GCDLGECRI--ALCEPG--EKHRLQKLQ-----LNFPSDDVAFALKD 798

Query: 776 NRSF 779
           N+  
Sbjct: 799 NKDL 802

ref|NP_701395.1| origin recognition complex 1 protein [Plasmodium falciparum 3D7]
gb|AAN36119.1| origin recognition complex 1 protein [Plasmodium falciparum 3D7]
gb|AAK54602.1| origin recognition complex 1 protein [Plasmodium falciparum]
(1189 aa)

Score: 181 bits (459), Expect: 7.21124e-44
Length: 315, Idn/Pos/Gap = 104/174/34 (33%/55%/10%)

Query:  348 VSEPTGSVPRLLQVSRFGAPRVQLVCRDVETERVLKFLTDCLRGS-SERCLYISGVPGTG  406
            + +PT    R++Q+     P+  L CR+ E + V  FL   ++ S S + LYISG+PGTG
Sbjct:  764 IKDPTDKAIRMMQLDV--VPKY-LPCREKEIKEVHGFLESGIKQSGSNQILYISGMPGTG  820

Query:  407 KTAVVRCAVQQLEQRRQQGQVPHFQYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRR  466
            KTA V   +Q L+ + ++  +P F   EINGM +  P  AY +  ++L ++        +
Sbjct:  821 KTATVYSVIQLLQIKSRKKLLPSFNVFEINGMNVVHPNAAYQVFYKQLFNK--------K  872

Query:  467 PPAPAEAARLLDQRFRQRRGVHNRKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWAS  526
            PP    + +++D+ F + +    + +    ++++DE+D L+       Q+VL+   DW +
Sbjct:  873 PPNALNSFKIIDRLFNKSQ----KDNRDVSILIIDEIDYLI----TKTQKVLFTLFDWPT  924

Query:  527 RPASELVIIGIANTLDLPERLLPRLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQHF  586
            +  S+L++I I+NT+DLP+RL+PR  SRL   R VF PY   ++++I++ +L     +  
Sbjct:  925 KINSKLILIAISNTMDLPDRLIPRCRSRLAFGRLVFSPYKGDEIEKIIKERL-ENCKEII  983

Query:  587 DEDALELCTRRVAAVSGDIRRALAICLHAYARSHSEDCSLRASENEHDRLVSAVDIDEAI  646
            D  A++LC R+VA VSGDIR+AL IC  A+             EN+    +   DI EA 
Sbjct:  984 DHTAIQLCARKVANVSGDIRKALQICRKAF-------------ENKRGHKIVPRDITEAT 1030

Query:  647 RELTPSSVQSAVKQL  661
             +L  S + +A+  L
Sbjct: 1031 NQLFDSPLTNAINYL 1045

emb|CAH98221.1| origin recognition complex 1 protein, putative [Plasmodium berghei]
(733 aa)

Score: 180 bits (457), Expect: 1.38247e-43
Length: 316, Idn/Pos/Gap = 108/173/36 (34%/54%/11%)

Query: 348 VSEPTGSVPRLLQVSRFGAPRVQLVCRDVETERVLKFLTDCLRGS-SERCLYISGVPGTG 406
           ++ PT    R++Q+     P+  L CR+ E + V  FL   ++ S S + LYISG+PGTG
Sbjct: 308 IAHPTDRAIRMMQLDV--VPKY-LPCREKEIKEVHGFLESGIKQSGSNQILYISGMPGTG 364

Query: 407 KTAVVRCAVQQLEQRRQQGQVPHFQYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRR 466
           KTA V   +Q L+ +  +  +P F   EINGM +  P  AY +  ++L +         +
Sbjct: 365 KTATVYSVIQLLKNKSNKKLLPPFNVYEINGMNVVHPNAAYQVFYKQLFNS--------K 416

Query: 467 PPAPAEAARLLDQRFRQRRGVHNRKHHSSILVLL-DEMDALVLNHSAAAQRVLYDFLDWA 525
           PP    + +++D+ F +     N+K + ++ +L+ DE+D L+       Q+VL+   DW 
Sbjct: 417 PPNALSSFKIIDRLFNK-----NKKDNRNVSILIIDEIDYLI----TKTQKVLFTLFDWP 467

Query: 526 SRPASELVIIGIANTLDLPERLLPRLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQH 585
           ++  S+L++I I+NT+DLPERL+PR  SRL   R VF PY   ++++I++ +L       
Sbjct: 468 TKVNSKLILIAISNTMDLPERLIPRCRSRLAFGRLVFSPYKGDEIEKIIKERL-YNCKDI 526

Query: 586 FDEDALELCTRRVAAVSGDIRRALAICLHAYARSHSEDCSLRASENEHDRLVSAVDIDEA 645
            D  A++LC R+VA VSGDIR+AL IC  A+             EN+    +   DI EA
Sbjct: 527 IDHTAIQLCARKVANVSGDIRKALQICRKAF-------------ENKRGHKIVPRDIIEA 573

Query: 646 IRELTPSSVQSAVKQL 661
             +L  S + +A+  L
Sbjct: 574 TNQLFDSPLTTAINYL 589

gb|AAH47200.1| Origin recognition complex, subunit 1-like [Danio rerio]
ref|NP_956227.1| origin recognition complex, subunit 1-like [Danio rerio]
(910 aa)

Score: 176 bits (447), Expect: 2.09876e-42
Length: 324, Idn/Pos/Gap = 117/186/29 (36%/57%/8%)

Query: 371 LVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHF 430
           L CR+ E + +  F+   +   +  C+YISGVPGTGKTA V   ++ L+Q  +Q ++PHF
Sbjct: 553 LPCREQELQDIYNFVESKVIDGTGGCMYISGVPGTGKTATVHEVIRSLQQSAEQDEIPHF 612

Query: 431 QYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHNR 490
            +IEINGM + DP +AY  +LQ+L  +   +           AA LL++RF         
Sbjct: 613 NFIEINGMKMTDPHQAYVQILQKLTDQKATS---------DHAAALLEKRF----SAPAP 659

Query: 491 KHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPER-LLP 549
           K  +++L++ +             Q V+Y+  DW +R  + LV++ IANT+DLPER ++ 
Sbjct: 660 KKETTVLLVDELDLLW-----TRKQNVMYNLFDWPTRRNARLVVLTIANTMDLPERIMIN 714

Query: 550 RLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQHFDEDALELCTRRVAAVSGDIRRAL 609
           R+ASRLG+ R  F+PY+  QLQQI+  +L    ++ F+EDAL+L +R+VAA+SGD RR L
Sbjct: 715 RVASRLGLTRMSFQPYTFKQLQQIITSRL--NRVKAFEEDALQLVSRKVAALSGDARRCL 772

Query: 610 AICLHAYARSHSEDCSLRASENEHDRLVSAVDIDEAIRELTPSSVQSAVKQLSQIEQQVL 669
            IC     R  +E C    ++ +   LV    + EA+ E+  SS  +A++  S ++ Q+L
Sbjct: 773 DIC-----RRATEICEHSGNQQKGSGLVGMSHVMEALDEMFSSSYIAAIRSAS-VQGQLL 826

Query: 670 MSAALCGRQAVQQGSETFRFQQIW 693
           + A +   +  + G E   FQQ++
Sbjct: 827 LRAVIA--EFRRLGLEEATFQQVF 848

ref|NP_808792.1| origin recognition complex, subunit 1 [Rattus norvegicus]
dbj|BAC65338.1| origin recognition complex subunit 1 [Rattus norvegicus]
(848 aa)

Score: 176 bits (446), Expect: 2.33921e-42
Length: 408, Idn/Pos/Gap = 141/206/47 (34%/50%/11%)

Query: 290 RSRQRAAAGRSRGNNCSQESDMTPRPRAGGQLLLWPSDVGAHEHRQSRISKNAVEFAEVS 349
           +SR R  A +      S+    T RPR              H   Q R    AV+     
Sbjct: 426 QSRTRRTASKPSSQTPSKSPKKTFRPRPP-----------LHATPQIRDRNLAVQ----- 469

Query: 350 EPTGSVPRLLQVSRFGAPRVQLVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTA 409
           EP   +          A    L CR+ E + +  F+   L   +  C+YISGVPGTGKTA
Sbjct: 470 EPASVLEEARLRLHVSAVPDSLPCREQEFQDIYSFVESKLLDGTGGCMYISGVPGTGKTA 529

Query: 410 VVRCAVQQLEQRRQQGQVPHFQYIEINGMTIPDPTRAYNILLQRL-GHRSTGAAGGRRPP 468
            V   ++ L+Q  Q   VP F+Y+E+NGM + +P + Y  +LQ+L G ++T         
Sbjct: 530 TVHEVIRCLQQAAQTNDVPPFEYVEVNGMKLTEPHQVYVQILQKLTGQKATA-------- 581

Query: 469 APAEAARLLDQRFRQRRGVHNRKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRP 528
               AA LL ++F       +R       VLL +   L+  H    Q VLY+  DW +  
Sbjct: 582 --NHAAELLAKQF------CSRGSQKETTVLLVDELDLLWTHK---QDVLYNLFDWPTHK 630

Query: 529 ASELVIIGIANTLDLPER-LLPRLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQHFD 587
            + LV++ IANT+DLPER ++ R+ASRLG+ R  F+PYS +QL+QIL  +L  + L+ F+
Sbjct: 631 GARLVVLTIANTMDLPERIMMNRVASRLGLTRMSFQPYSHSQLKQILVSRL--KHLKAFE 688

Query: 588 EDALELCTRRVAAVSGDIRRALAICLHAYARSHSEDCSLRASENEHDRLVSAVDIDEAIR 647
           +DA++L  R+VAA+SGD RR L IC     R  +E C +     +   LV+   + EAI 
Sbjct: 689 DDAVQLVARKVAALSGDARRCLDIC-----RRATEICEVSHQRGDSQCLVTVAHLMEAID 743

Query: 648 ELTPSSVQSAVKQLSQIEQQVLMSAALCGRQAVQQGSETFRFQQIWHR 695
           E+  SS  +A+K  S +EQ  L +     R++   G E   FQQI+ +
Sbjct: 744 EMFSSSYITAIKNSSVLEQSFLRAIIAEFRRS---GLEEATFQQIYSQ 788

emb|CAG31118.1| hypothetical protein [Gallus gallus]
(858 aa)

Score: 176 bits (446), Expect: 2.65109e-42
Length: 326, Idn/Pos/Gap = 119/182/30 (36%/55%/9%)

Query: 371 LVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHF 430
           L CR+ E + +  F+   L   +  C+YISGVPGTGKTA V   ++ L++  +   +P F
Sbjct: 502 LPCREEEFQDIYNFVESKLIDGTGGCMYISGVPGTGKTATVHEVIRCLQRATEDDDLPSF 561

Query: 431 QYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHNR 490
           Q+IEINGM + DP +AY  +L+ L  +   A           AA LL   F         
Sbjct: 562 QFIEINGMKLTDPHQAYVQILELLTGQKVTA---------THAAVLLANLF----CTPGP 608

Query: 491 KHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPER-LLP 549
           K  +++LV +DE+D L        Q V+Y+  DW ++  S+L+I+ IANT+DLPER ++ 
Sbjct: 609 KRKTTVLV-VDELDLL----WTRKQNVMYNLFDWPTQKHSKLIILAIANTMDLPERIMMN 663

Query: 550 RLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQHFDEDALELCTRRVAAVSGDIRRAL 609
           R++SRLG+ R  F+PY+  QLQQI+  +L    ++ F+EDA++L +R+VAA+SGD RR L
Sbjct: 664 RVSSRLGLTRMSFQPYTYKQLQQIISSRLNS--VKAFEEDAIQLVSRKVAALSGDARRCL 721

Query: 610 AICLHAYARSHSEDCSLRASENEHDRLVSAVDIDEAIRELTPSSVQSAVKQLSQIEQQVL 669
            IC     R  +E C   +S+   D +V    I +AI E+  S    A++  S + +Q+ 
Sbjct: 722 DIC-----RRAAEICEF-SSQKSTDEIVRMTHITQAIDEMFSSPYIQAIRNAS-LHEQIF 774

Query: 670 MSAALCGRQAVQQGSETFRFQQIWHR 695
             A L   + V  G E    QQ++ +
Sbjct: 775 FKAILAEFRRV--GVEEATVQQVYRQ 798

emb|CAB78305.1| origin recognition complex subunit 1-like protein [Arabidopsis thaliana]
emb|CAB53755.1| origin recognition complex subunit 1-like protein [Arabidopsis thaliana]
emb|CAD20132.1| origin recognition complex 1b protein [Arabidopsis thaliana]
pir||E85135 hypothetical protein AT4g12620 [imported] - Arabidopsis thaliana
ref|NP_192999.1| replication control protein, putative [Arabidopsis thaliana]
(813 aa)

Score: 176 bits (445), Expect: 3.15879e-42
Length: 419, Idn/Pos/Gap = 130/216/47 (31%/51%/11%)

Query: 371 LVCRDVETERVLKFLTDCLRGSS--ERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVP 428
           L CR  E E +  F+   +       RC+YI GVPGTGKT  V   ++ L+   ++G V 
Sbjct: 439 LPCRSKEMEEITSFIKGSISDDQCLGRCMYIHGVPGTGKTISVLSVMKNLKAEVEEGSVS 498

Query: 429 HFQYIEINGMTIPDPTRAYNILLQRL-GHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGV 487
            + ++EING+ +  P   Y+++ + L GHR     G ++      A + L++RF + + +
Sbjct: 499 PYCFVEINGLKLASPENIYSVIYEALSGHR----VGWKK------ALQCLNERFAEGKRI 548

Query: 488 HNRKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERL 547
                   IL++ +    +  N     Q VLY+ LDW ++P S+LV++GIANT+DLPE+L
Sbjct: 549 GKEDEKPCILLIDELDLLVTRN-----QSVLYNILDWPTKPNSKLVVLGIANTMDLPEKL 603

Query: 548 LPRLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQHFDEDALELCTRRVAAVSGDIRR 607
           LPR++SR+G+ R  F PY+ TQLQ+I+  +L    +  F++ A+E  +R+VAA+SGD RR
Sbjct: 604 LPRISSRMGIQRLCFGPYNHTQLQEIISTRLNG--IDAFEKTAIEFASRKVAAISGDARR 661

Query: 608 ALAICLHAYARSHSEDCSLRASENEHDRLVSAVDIDEAIRELTPSSVQSAVKQLSQIEQQ 667
           AL IC  A   +   D  L  +++  ++LV   D++ AI+E+  +     +K +S++  +
Sbjct: 662 ALEICRRA---AEVADHRLNTNKSAKNQLVIMADVEAAIQEMFQAPHIQVMKSVSKL-SK 717

Query: 668 VLMSAALCGRQAVQQGSETFRFQQIWHRFRQFHASTEGHPAYPLPLQDQIEEVWHILMGL 727
           + ++A +   +  + G     F ++          T G  A+P          W IL+ +
Sbjct: 718 IFLTAMV--HELYKTGMAETTFDRVATTVSSI-CLTNGE-AFP---------GWDILLKI 764

Query: 728 CACNLLSCSVPSSSCAYAGFASTRLPNLHESQFVLNPLFDDIAFAFRENRSFAQAAGEL 786
             C+L  C +             RL  L      LN   DD+AFA ++N+     A  L
Sbjct: 765 -GCDLGECRIILCEPG----EKHRLQKLQ-----LNFPSDDVAFALKDNKDLPWLANYL 813

ref|XP_532575.1| PREDICTED: similar to origin recognition complex, subunit 1 [Canis familiaris]
(762 aa)

Score: 176 bits (445), Expect: 3.60993e-42
Length: 365, Idn/Pos/Gap = 125/193/38 (34%/52%/10%)

Query: 371 LVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHF 430
           L CR+ E + +  F+   L   +  C+YISGVPGTGKTA V   ++ L+Q  +   VP F
Sbjct: 406 LPCREQEFQNIYNFVESKLLDHTGGCMYISGVPGTGKTATVHEVIRCLQQAAKANDVPPF 465

Query: 431 QYIEINGMTIPDPTRAYNILLQRL-GHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHN 489
           QYIE+NGM + +P + Y  +LQ+L G ++T             AA LL +RF  +R    
Sbjct: 466 QYIEVNGMKLTEPHQVYVQILQKLTGQKATA----------NHAAELLAKRFLTQRSSQE 515

Query: 490 RKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPER-LL 548
                        +   +       Q V+Y+  DW +   + LV++ IANT+DLPER ++
Sbjct: 516 TT---------VLLVDELDLLWTQKQDVMYNLFDWPTHKEARLVVLTIANTMDLPERIMM 566

Query: 549 PRLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQHFDEDALELCTRRVAAVSGDIRRA 608
            R++SRLG+ R  F+PY+ +QLQQIL  +L  + ++ F++DA++L  R+VAA+SGD RR 
Sbjct: 567 NRVSSRLGLTRMSFQPYTHSQLQQILISRL--KNIKAFEDDAIQLVARKVAALSGDARRC 624

Query: 609 LAICLHAYARSHSEDCSLRASENEHDRLVSAVDIDEAIRELTPSSVQSAVKQLSQIEQQV 668
           L IC     R  +E C     + +   LV+   + +A+ E+  SS  +A+K  S +EQ  
Sbjct: 625 LDIC-----RRATEICEFSCRKPDSPGLVTIAHLLQAVDEMFSSSYITAIKNSSVLEQSF 679

Query: 669 LMSAALCGRQAVQQGSETFRFQQIWHRFRQFHASTEGHPAYPLPLQDQIEEVWHILMGLC 728
           L +     R++   G E   FQQ++ +        EG P YP      + E   +   L 
Sbjct: 680 LRAILAEFRRS---GLEEATFQQVYSQHVAL-CRMEGLP-YP-----TMSETMAVCSNLG 729

Query: 729 ACNLL 733
           +C+LL
Sbjct: 730 SCHLL 734

sp|Q13415|ORC1_HUMAN Origin recognition complex subunit 1 (Replication control protein 1)
gb|AAC50325.1| HsORC1
(861 aa)

Score: 174 bits (442), Expect: 7.52281e-42
Length: 365, Idn/Pos/Gap = 133/196/38 (36%/53%/10%)

Query: 371 LVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHF 430
           L CR+ E + +  F+   L   +  C+YISGVPGTGKTA V   ++ L+Q  Q   VP F
Sbjct: 504 LPCREQEFQDIYNFVESKLLDHTGGCMYISGVPGTGKTATVHEVIRCLQQAAQANDVPPF 563

Query: 431 QYIEINGMTIPDPTRAYNILLQRL-GHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHN 489
           QYIE+NGM + +P + Y  +LQ+L G ++T             AA LL ++F        
Sbjct: 564 QYIEVNGMKLTEPHQVYVHILQKLTGQKATA----------NHAAELLAKQF------CT 607

Query: 490 RKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPER-LL 548
           R       VLL +   L+  H    Q ++Y+  DW +   + LV++ IANT+DLPER ++
Sbjct: 608 RGSPQETTVLLVDELDLLWTHK---QDIMYNLFDWPTHKEARLVVLAIANTMDLPERIMM 664

Query: 549 PRLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQHFDEDALELCTRRVAAVSGDIRRA 608
            R++SRLG+ R  F+PY+ +QLQQILR +L  + L+ F++DA++L  R+VAA+SGD RR 
Sbjct: 665 NRVSSRLGLTRMCFQPYTYSQLQQILRSRL--KHLKAFEDDAIQLVARKVAALSGDARRC 722

Query: 609 LAICLHAYARSHSEDCSLRASENEHDRLVSAVDIDEAIRELTPSSVQSAVKQLSQIEQQV 668
           L IC     R  +E C     + +   LV+     EA+ E+  SS  +A+K  S +EQ  
Sbjct: 723 LDIC-----RRATEICEFSQQKPDSPGLVTIAHSMEAVDEMFSSSYITAIKNSSVLEQSF 777

Query: 669 LMSAALCGRQAVQQGSETFRFQQIWHRFRQFHASTEGHPAYPLPLQDQIEEVWHILMGLC 728
           L +     R++   G E   FQQI+ +        EG P YP      + E   +   L 
Sbjct: 778 LRAILAEFRRS---GLEEATFQQIYSQHVAL-CRMEGLP-YP-----TMSETMAVCSHLG 827

Query: 729 ACNLL 733
           +C LL
Sbjct: 828 SCRLL 832

gb|AAH11539.1| Origin recognition complex, subunit 1 [Homo sapiens]
(861 aa)

Score: 174 bits (442), Expect: 7.84329e-42
Length: 365, Idn/Pos/Gap = 133/196/38 (36%/53%/10%)

Query: 371 LVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHF 430
           L CR+ E + +  F+   L   +  C+YISGVPGTGKTA V   ++ L+Q  Q   VP F
Sbjct: 504 LPCREQEFQDIYNFVESKLLDHTGGCMYISGVPGTGKTATVHEVIRCLQQAAQANDVPPF 563

Query: 431 QYIEINGMTIPDPTRAYNILLQRL-GHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHN 489
           QYIE+NGM + +P + Y  +LQ+L G ++T             AA LL ++F        
Sbjct: 564 QYIEVNGMKLTEPHQVYVQILQKLTGQKATA----------NHAAELLAKQF------CT 607

Query: 490 RKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPER-LL 548
           R       VLL +   L+  H    Q ++Y+  DW +   + LV++ IANT+DLPER ++
Sbjct: 608 RGSPQETTVLLVDELDLLWTHK---QDIMYNLFDWPTHKEARLVVLAIANTMDLPERIMM 664

Query: 549 PRLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQHFDEDALELCTRRVAAVSGDIRRA 608
            R++SRLG+ R  F+PY+ +QLQQILR +L  + L+ F++DA++L  R+VAA+SGD RR 
Sbjct: 665 NRVSSRLGLTRMCFQPYTYSQLQQILRSRL--KHLKAFEDDAIQLVARKVAALSGDARRC 722

Query: 609 LAICLHAYARSHSEDCSLRASENEHDRLVSAVDIDEAIRELTPSSVQSAVKQLSQIEQQV 668
           L IC     R  +E C     + +   LV+     EA+ E+  SS  +A+K  S +EQ  
Sbjct: 723 LDIC-----RRATEICEFSQQKPDSPGLVTIAHSMEAVDEMFSSSYITAIKNSSVLEQSF 777

Query: 669 LMSAALCGRQAVQQGSETFRFQQIWHRFRQFHASTEGHPAYPLPLQDQIEEVWHILMGLC 728
           L +     R++   G E   FQQI+ +        EG P YP      + E   +   L 
Sbjct: 778 LRAILAEFRRS---GLEEATFQQIYSQHVAL-CRMEGLP-YP-----TMSETMAVCSHLG 827

Query: 729 ACNLL 733
           +C LL
Sbjct: 828 SCRLL 832

emb|CAI12288.1| origin recognition complex, subunit 1-like (yeast) [Homo sapiens]
gb|AAA86260.1| replication control protein 1
ref|NP_004144.2| origin recognition complex, subunit 1 [Homo sapiens]
(861 aa)

Score: 174 bits (442), Expect: 7.84329e-42
Length: 365, Idn/Pos/Gap = 133/196/38 (36%/53%/10%)

Query: 371 LVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHF 430
           L CR+ E + +  F+   L   +  C+YISGVPGTGKTA V   ++ L+Q  Q   VP F
Sbjct: 504 LPCREQEFQDIYNFVESKLLDHTGGCMYISGVPGTGKTATVHEVIRCLQQAAQANDVPPF 563

Query: 431 QYIEINGMTIPDPTRAYNILLQRL-GHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHN 489
           QYIE+NGM + +P + Y  +LQ+L G ++T             AA LL ++F        
Sbjct: 564 QYIEVNGMKLTEPHQVYVQILQKLTGQKATA----------NHAAELLAKQF------CT 607

Query: 490 RKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPER-LL 548
           R       VLL +   L+  H    Q ++Y+  DW +   + LV++ IANT+DLPER ++
Sbjct: 608 RGSPQETTVLLVDELDLLWTHK---QDIMYNLFDWPTHKEARLVVLAIANTMDLPERIMM 664

Query: 549 PRLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQHFDEDALELCTRRVAAVSGDIRRA 608
            R++SRLG+ R  F+PY+ +QLQQILR +L  + L+ F++DA++L  R+VAA+SGD RR 
Sbjct: 665 NRVSSRLGLTRMCFQPYTYSQLQQILRSRL--KHLKAFEDDAIQLVARKVAALSGDARRC 722

Query: 609 LAICLHAYARSHSEDCSLRASENEHDRLVSAVDIDEAIRELTPSSVQSAVKQLSQIEQQV 668
           L IC     R  +E C     + +   LV+     EA+ E+  SS  +A+K  S +EQ  
Sbjct: 723 LDIC-----RRATEICEFSQQKPDSPGLVTIAHSMEAVDEMFSSSYITAIKNSSVLEQSF 777

Query: 669 LMSAALCGRQAVQQGSETFRFQQIWHRFRQFHASTEGHPAYPLPLQDQIEEVWHILMGLC 728
           L +     R++   G E   FQQI+ +        EG P YP      + E   +   L 
Sbjct: 778 LRAILAEFRRS---GLEEATFQQIYSQHVAL-CRMEGLP-YP-----TMSETMAVCSHLG 827

Query: 729 ACNLL 733
           +C LL
Sbjct: 828 SCRLL 832

gb|AAF66067.1| origin recognition complex subunit 1 [Cricetulus griseus]
sp|Q9JI69|ORC1_CRIGR Origin recognition complex subunit 1
(850 aa)

Score: 173 bits (439), Expect: 1.7473e-41
Length: 388, Idn/Pos/Gap = 130/199/38 (33%/51%/9%)

Query: 348 VSEPTGSVPRLLQVSRFGAPRVQLVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGK 407
           V EPT  +     +    A    L CR+ E + +  F+   L   +  C+YISGVPGTGK
Sbjct: 470 VQEPTSVLEEARLMLHVSAVPDSLPCREQEFQDIYSFVESKLLDGTGGCMYISGVPGTGK 529

Query: 408 TAVVRCAVQQLEQRRQQGQVPHFQYIEINGMTIPDPTRAYNILLQRL-GHRSTGAAGGRR 466
           TA V   ++ L+Q  Q   VP F+Y+++NGM + +P + Y  +LQ+L G ++T       
Sbjct: 530 TATVNEVIRCLQQAAQTNDVPPFEYVDVNGMKLTEPHQVYVQILQKLTGQKATA------ 583

Query: 467 PPAPAEAARLLDQRFRQRRGVHNRKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWAS 526
                 AA+LL +RF  +          S       +   +     + Q V+Y+  DW +
Sbjct: 584 ----NHAAQLLAKRFCSQ---------GSQQETTVLLVDELDLLWTSKQDVMYNLFDWPT 630

Query: 527 RPASELVIIGIANTLDLPER-LLPRLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQH 585
              + L+++ IANT+DLPER ++ R++SRLG+ R  F+PYS  QL++IL  +L  + L+ 
Sbjct: 631 HKGARLIVLAIANTMDLPERIMMNRVSSRLGLTRMSFQPYSHNQLKEILVSRL--KHLKA 688

Query: 586 FDEDALELCTRRVAAVSGDIRRALAICLHAYARSHSEDCSLRASENEHDRLVSAVDIDEA 645
           F++DA++L  R+VAA+SGD RR L IC     R  +E C L  +       V+   + EA
Sbjct: 689 FEDDAIQLVARKVAALSGDARRCLDIC-----RRATEICELSHNHGNSLGPVTVSHLMEA 743

Query: 646 IRELTPSSVQSAVKQLSQIEQQVLMSAALCGRQAVQQGSETFRFQQIWHRFRQFHASTEG 705
           I E+  SS  +A+K  S +EQ  L +     R++   G E   FQQI+ +        EG
Sbjct: 744 IDEMFSSSYITAIKNCSLLEQGFLRAIIAEFRRS---GLEEATFQQIYSQHVAL-CRMEG 799

Query: 706 HPAYPLPLQDQIEEVWHILMGLCACNLL 733
            P YP      + E   +   L +C LL
Sbjct: 800 LP-YP-----TMSETMAVCSNLGSCRLL 821

gb|AAH90562.1| XORC1 protein [Xenopus laevis]
(886 aa)

Score: 172 bits (437), Expect: 2.52237e-41
Length: 355, Idn/Pos/Gap = 123/192/36 (34%/54%/10%)

Query: 347 EVSEPTGSVPRLLQVSRF----GAPRVQLVCRDVETERVLKFLTDCLRGSSERCLYISGV 402
           E ++P      +L+ +R      A    L CR+ E + V  F+   L   +  C+YISGV
Sbjct: 502 ERNQPVKKPSNMLEEARIRLHVSAVPESLPCREQEYQDVYNFVESKLLDGTGGCMYISGV 561

Query: 403 PGTGKTAVVRCAVQQLEQRRQQGQVPHFQYIEINGMTIPDPTRAYNILLQRL-GHRSTGA 461
           PGTGKTA V   ++ L++  ++ ++P F YIEINGM + DP +AY  +L+ L G ++T  
Sbjct: 562 PGTGKTATVHEVIRSLQESAEEEELPMFHYIEINGMKLTDPHQAYVQILKLLTGQKATA- 620

Query: 462 AGGRRPPAPAEAARLLDQRFRQRRGVHNRKHHSSILVLLDEMDALVLNHSAAAQRVLYDF 521
                      AA LL++RF         K  +++L++ +             Q V+Y  
Sbjct: 621 ---------DHAAALLEKRF----STPASKKETTVLLVDELDLLW-----TRKQNVMYSL 662

Query: 522 LDWASRPASELVIIGIANTLDLPER-LLPRLASRLGMNRQVFKPYSVTQLQQILRHKLGP 580
            DW +R  ++L+++ IANT+DLPER ++ R+ASRLG+ R  F+PY+  QLQQI+  +L  
Sbjct: 663 FDWPTRKQAKLIVLAIANTMDLPERIMMNRVASRLGLTRMSFQPYTHKQLQQIITSRLNH 722

Query: 581 QLLQHFDEDALELCTRRVAAVSGDIRRALAICLHAYARSHSEDCSLRASENEHDRLVSAV 640
             ++ FD+DA++L  R+VAA+SGD RR L IC     R  +E C    S  +   LV   
Sbjct: 723 --IKAFDDDAIQLVARKVAALSGDARRCLDIC-----RRATEICEFSHSMAD-SSLVKMS 774

Query: 641 DIDEAIRELTPSSVQSAVKQLSQIEQQVLMSAALCGRQAVQQGSETFRFQQIWHR 695
            + EA+ E+  S   +A++  S +EQ  L +     R++   G E   FQQI+ +
Sbjct: 775 HVIEALEEMFSSPYVTAIRNSSLMEQTFLRAVIAEFRRS---GLEEATFQQIYRQ 826

ref|NP_477303.1| CG10667-PA [Drosophila melanogaster]
gb|AAF59236.1| CG10667-PA [Drosophila melanogaster]
gb|AAM11133.1| LD11626p [Drosophila melanogaster]
sp|O16810|ORC1_DROME Origin recognition complex subunit 1 (DmORC1)
(924 aa)

Score: 172 bits (437), Expect: 2.5435e-41
Length: 324, Idn/Pos/Gap = 112/185/32 (34%/57%/9%)

Query: 371 LVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHF 430
           L CR+ E E +  FL   ++     C+Y+SGVPGTGKTA V   ++ L++  +Q ++P F
Sbjct: 568 LPCREREFENIYAFLEGKIQDQCGGCMYVSGVPGTGKTATVTGVIRTLQRMAKQNELPAF 627

Query: 431 QYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHNR 490
           +Y+EINGM + +P +AY  + ++L  ++          +  +A  LL++RF         
Sbjct: 628 EYLEINGMRLTEPRQAYVQIYKQLTGKTV---------SWEQAHALLEKRF-----TTPA 673

Query: 491 KHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLL-P 549
               + ++L+DE+D L        Q V+Y+ LDW ++ A++LV++ IANT+DLPERLL  
Sbjct: 674 PRRVTTVLLVDELDILCNRR----QDVVYNLLDWPTKSAAKLVVVTIANTMDLPERLLMG 729

Query: 550 RLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQHFDEDALELCTRRVAAVSGDIRRAL 609
           ++ SRLG+ R  F+PYS  QLQ+I+  +LG    + F  +A++L  R+VAAVSGD RRAL
Sbjct: 730 KVTSRLGLTRLTFQPYSHKQLQEIVTARLGGS--ETFKGEAVQLVARKVAAVSGDARRAL 787

Query: 610 AICLHAYARSHSEDCSLRASENEHDRLVSAVDIDEAIRELTPSSVQSAVKQLSQIEQQVL 669
            IC  A             ++    + V+ + + +A+ E+  S+   A++  S++EQ  L
Sbjct: 788 DICRRA----------TEIADTAAVKCVTMLHVQQALAEMIASAKVQAIRNCSRMEQIFL 837

Query: 670 MS-AALCGRQAVQQGSETFRFQQI 692
            + AA   R  V++ +    +QQ+
Sbjct: 838 QAIAAEVTRTGVEETTFMGVYQQV 861

gb|AAC60033.1| origin recognition complex protein 1 [Xenopus laevis]
(886 aa)

Score: 172 bits (437), Expect: 2.65186e-41
Length: 355, Idn/Pos/Gap = 123/192/36 (34%/54%/10%)

Query: 347 EVSEPTGSVPRLLQVSRF----GAPRVQLVCRDVETERVLKFLTDCLRGSSERCLYISGV 402
           E ++P      +L+ +R      A    L CR+ E + V  F+   L   +  C+YISGV
Sbjct: 502 ERNQPVKKPSNMLEEARIRLHVSAVPESLPCREQEYQDVYNFVESKLLDGTGGCMYISGV 561

Query: 403 PGTGKTAVVRCAVQQLEQRRQQGQVPHFQYIEINGMTIPDPTRAYNILLQRL-GHRSTGA 461
           PGTGKTA V   ++ L++  ++ ++P F YIEINGM + DP +AY  +L+ L G ++T  
Sbjct: 562 PGTGKTATVHEVIRSLQESAEEEELPMFHYIEINGMKLTDPHQAYVQILKLLTGQKATA- 620

Query: 462 AGGRRPPAPAEAARLLDQRFRQRRGVHNRKHHSSILVLLDEMDALVLNHSAAAQRVLYDF 521
                      AA LL++RF         K  +++L++ +             Q V+Y  
Sbjct: 621 ---------DHAAALLEKRF----STPASKKETTVLLVDELDLLW-----TRKQNVMYSL 662

Query: 522 LDWASRPASELVIIGIANTLDLPER-LLPRLASRLGMNRQVFKPYSVTQLQQILRHKLGP 580
            DW +R  ++L+++ IANT+DLPER ++ R+ASRLG+ R  F+PY+  QLQQI+  +L  
Sbjct: 663 FDWPTRKQAKLIVLAIANTMDLPERIMMNRVASRLGLTRMSFQPYTHKQLQQIITSRLNH 722

Query: 581 QLLQHFDEDALELCTRRVAAVSGDIRRALAICLHAYARSHSEDCSLRASENEHDRLVSAV 640
             ++ FD+DA++L  R+VAA+SGD RR L IC     R  +E C    S  +   LV   
Sbjct: 723 --IKAFDDDAIQLVARKVAALSGDARRCLDIC-----RRATEICEFSHSMAD-SSLVKMS 774

Query: 641 DIDEAIRELTPSSVQSAVKQLSQIEQQVLMSAALCGRQAVQQGSETFRFQQIWHR 695
            + EA+ E+  S   +A++  S +EQ  L +     R++   G E   FQQI+ +
Sbjct: 775 HVIEALEEMFSSPYVTAIRNSSLMEQTFLRAVIAEFRRS---GLEEATFQQIYRQ 826

gb|AAC47802.1| origin recognition complex subunit 1 [Drosophila melanogaster]
(924 aa)

Score: 172 bits (437), Expect: 2.81136e-41
Length: 324, Idn/Pos/Gap = 112/185/32 (34%/57%/9%)

Query: 371 LVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHF 430
           L CR+ E E +  FL   ++     C+Y+SGVPGTGKTA V   ++ L++  +Q ++P F
Sbjct: 568 LPCREREFENIYAFLEGKIQDQCGGCMYVSGVPGTGKTATVTGVIRTLQRMAKQNELPAF 627

Query: 431 QYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHNR 490
           +Y+EINGM + +P +AY  + ++L  ++          +  +A  LL++RF         
Sbjct: 628 EYLEINGMRLTEPRQAYVQIYKQLTGKTV---------SWEQAHALLEKRF-----TTPA 673

Query: 491 KHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLL-P 549
               + ++L+DE+D L        Q V+Y+ LDW ++ A++LV++ IANT+DLPERLL  
Sbjct: 674 PRRVTTVLLVDELDILCNRR----QDVVYNLLDWPTKSAAKLVVVTIANTMDLPERLLMG 729

Query: 550 RLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQHFDEDALELCTRRVAAVSGDIRRAL 609
           ++ SRLG+ R  F+PYS  QLQ+I+  +LG    + F  +A++L  R+VAAVSGD RRAL
Sbjct: 730 KVTSRLGLTRLTFQPYSHKQLQEIVTARLGGS--ETFKGEAVQLVARKVAAVSGDARRAL 787

Query: 610 AICLHAYARSHSEDCSLRASENEHDRLVSAVDIDEAIRELTPSSVQSAVKQLSQIEQQVL 669
            IC  A             ++    + V+ + + +A+ E+  S+   A++  S++EQ  L
Sbjct: 788 DICRRA----------TEIADTAAVKCVTMLHVQQALAEMIASAKVQAIRNCSRMEQIFL 837

Query: 670 MS-AALCGRQAVQQGSETFRFQQI 692
            + AA   R  V++ +    +QQ+
Sbjct: 838 QAIAAEVTRTGVEETTFMGVYQQV 861

ref|NP_001014425.1| origin recognition complex, subunit 1 isoform B [Mus musculus]
dbj|BAD91663.1| origin recognition complex subunit 1 isoform B [Mus musculus]
(805 aa)

Score: 172 bits (436), Expect: 3.58098e-41
Length: 388, Idn/Pos/Gap = 134/202/38 (34%/52%/9%)

Query: 348 VSEPTGSVPRLLQVSRFGAPRVQLVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGK 407
           V EP  ++          A    L CR+ E + +  F+   L   +  C+YISGVPGTGK
Sbjct: 425 VQEPASALEEARLRLHVSAVPDSLPCREQEFQDIYSFVESKLLDGTGGCMYISGVPGTGK 484

Query: 408 TAVVRCAVQQLEQRRQQGQVPHFQYIEINGMTIPDPTRAYNILLQRL-GHRSTGAAGGRR 466
           TA V   ++ L+Q  +   VP FQY+E+NGM + +P + Y  +L++L G ++T       
Sbjct: 485 TATVHEVIRCLQQAAETDDVPPFQYVEVNGMKLTEPHQVYVQILKKLTGQKATA------ 538

Query: 467 PPAPAEAARLLDQRFRQRRGVHNRKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWAS 526
                 AA LL ++F        +       VLL +   L+  H    Q V+Y+  DW +
Sbjct: 539 ----NHAAELLAKQF------CGQGSQKETTVLLVDELDLLWTHK---QDVMYNLFDWPT 585

Query: 527 RPASELVIIGIANTLDLPER-LLPRLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQH 585
              + L+++ IANT+DLPER ++ R++SRLG+ R  F+PYS +QL+QIL  +L  + L+ 
Sbjct: 586 HKGAHLIVLTIANTMDLPERIMMNRVSSRLGLTRMSFQPYSHSQLKQILVSRL--RNLRA 643

Query: 586 FDEDALELCTRRVAAVSGDIRRALAICLHAYARSHSEDCSLRASENEHDRLVSAVDIDEA 645
           F++DA++L  R+VAA+SGD RR L IC     R  +E C L     +   LV+   + EA
Sbjct: 644 FEDDAIQLVARKVAALSGDARRCLDIC-----RRATEICELSHLRGDSLSLVTVAHLMEA 698

Query: 646 IRELTPSSVQSAVKQLSQIEQQVLMSAALCGRQAVQQGSETFRFQQIWHRFRQFHASTEG 705
           I E+  SS  +A+K  S +EQ  L +     R++   G E   FQQI+ +        EG
Sbjct: 699 IDEMFSSSYITAIKNSSVVEQSFLRAIIAEFRRS---GLEEATFQQIYSQHVAL-CRMEG 754

Query: 706 HPAYPLPLQDQIEEVWHILMGLCACNLL 733
            P YP      + E   +   L +C LL
Sbjct: 755 LP-YP-----TMSETMAVCSRLGSCRLL 776

gb|EAL65980.1| hypothetical protein DDB0218435 [Dictyostelium discoideum]
(631 aa)

Score: 172 bits (435), Expect: 4.52339e-41
Length: 257, Idn/Pos/Gap = 96/163/17 (37%/63%/6%)

Query: 370 QLVCRDVETERVLKFLTDCLRGS-SERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVP 428
           +L  R+ E   +  F+   L+ + S  CLYI+G+PGTGKTA V+  +++L+ +++Q    
Sbjct: 233 KLPGREKEKATIASFIRAKLKANESGGCLYIAGMPGTGKTATVKEIIKELQAKKKQQGGG 292

Query: 429 ---HFQYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRR 485
              +FQ+IEINGM + DP + Y+IL  ++  + T  +   +  +  +A RL+ + F    
Sbjct: 293 GGLNFQFIEINGMQLSDPHQLYHILYNKM--QKTRKSLEPKKISSQDALRLIQRNFE--- 347

Query: 486 GVHNRKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPE 545
            + N+K    + +L+DE D+L+       Q V+Y+  +W ++P S+L+II IANT++LP+
Sbjct: 348 -LKNKKKQFRV-ILVDEFDSLI----TKKQTVIYNLFEWPNKPNSKLIIIAIANTMNLPD 401

Query: 546 RLLPRLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQHFDEDALELCTRRVAAVSGDI 605
            LLPR+ SR+G+ +  F PY++ QL+ I++++L  Q L  FDE+++++C++RVAAV GD 
Sbjct: 402 TLLPRVKSRMGLQKVPFTPYNIEQLETIIKYRL--QDLDAFDEESIQICSKRVAAVCGDA 459

Query: 606 RRALAICLHAYARSHSE 622
           RRAL IC  A   ++ E
Sbjct: 460 RRALEICRKAATIANQE 476

ref|XP_422474.1| PREDICTED: similar to origin recognition complex protein 1 [Gallus gallus]
(1944 aa)

Score: 171 bits (434), Expect: 5.61925e-41
Length: 333, Idn/Pos/Gap = 120/185/29 (36%/55%/8%)

Query: 371 LVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHF 430
           L CR+ E + +  F+   L   +  C+YISGVPGTGKTA V   ++ L++  +   +P F
Sbjct: 573 LPCREEEFQDIYNFVESKLIDGTGGCMYISGVPGTGKTATVHEVIRCLQRATEDDDLPSF 632

Query: 431 QYIEINGMTIPDPTRAYNILLQRLGHRS-------TGAAGGRRPPAPAEAARLLDQRFRQ 483
           Q+IEINGM + DP +AY  +L+  G  +            G++  A   AA LL   F  
Sbjct: 633 QFIEINGMKLTDPHQAYVQILESSGVINLQYNLILVQLLTGQKVTA-THAAVLLANLF-- 689

Query: 484 RRGVHNRKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDL 543
                  K  +++LV +DE+D L        Q V+Y+  DW ++  S+L+I+ IANT+DL
Sbjct: 690 --CTPGPKRKTTVLV-VDELDLL----WTRKQNVMYNLFDWPTQKHSKLIILAIANTMDL 742

Query: 544 PER-LLPRLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQHFDEDALELCTRRVAAVS 602
           PER ++ R++SRLG+ R  F+PY+  QLQQI+  +L    ++ F+EDA++L +R+VAA+S
Sbjct: 743 PERIMMNRVSSRLGLTRMSFQPYTYKQLQQIISSRLNS--VKAFEEDAIQLVSRKVAALS 800

Query: 603 GDIRRALAICLHAYARSHSEDCSLRASENEHDRLVSAVDIDEAIRELTPSSVQSAVKQLS 662
           GD RR L IC     R  +E C   +S+   D +V    I +AI E+  S    A++  S
Sbjct: 801 GDARRCLDIC-----RRAAEICEF-SSQKSTDEIVRMTHITQAIDEMFSSPYIQAIRNAS 854

Query: 663 QIEQQVLMSAALCGRQAVQQGSETFRFQQIWHR 695
            + +Q+   A L   + V  G E    QQ++ +
Sbjct: 855 -LHEQIFFKAILAEFRRV--GVEEATVQQVYRQ 884

dbj|BAC31178.1| unnamed protein product [Mus musculus]
(840 aa)

Score: 171 bits (434), Expect: 6.86508e-41
Length: 388, Idn/Pos/Gap = 134/202/38 (34%/52%/9%)

Query: 348 VSEPTGSVPRLLQVSRFGAPRVQLVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGK 407
           V EP  ++          A    L CR+ E + +  F+   L   +  C+YISGVPGTGK
Sbjct: 460 VQEPASALEEARLRLHVSAVPDSLPCREQEFQDIYSFVESKLLDGTGGCMYISGVPGTGK 519

Query: 408 TAVVRCAVQQLEQRRQQGQVPHFQYIEINGMTIPDPTRAYNILLQRL-GHRSTGAAGGRR 466
           TA V   ++ L+Q  +   VP FQY+E+NGM + +P + Y  +L++L G ++T       
Sbjct: 520 TATVHEVIRCLQQAAETDDVPPFQYVEVNGMKLTEPHQVYVQILKKLTGQKATA------ 573

Query: 467 PPAPAEAARLLDQRFRQRRGVHNRKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWAS 526
                 AA LL ++F        +       VLL +   L+  H    Q V+Y+  DW +
Sbjct: 574 ----NHAAELLAKQF------CGQGSQKETTVLLVDELDLLWTHK---QDVMYNLFDWPT 620

Query: 527 RPASELVIIGIANTLDLPER-LLPRLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQH 585
              + L+++ IANT+DLPER ++ R++SRLG+ R  F+PYS +QL+QIL  +L  + L+ 
Sbjct: 621 HKGAHLIVLTIANTMDLPERIMMNRVSSRLGLTRMSFQPYSHSQLKQILVSRL--RNLRA 678

Query: 586 FDEDALELCTRRVAAVSGDIRRALAICLHAYARSHSEDCSLRASENEHDRLVSAVDIDEA 645
           F++DA++L  R+VAA+SGD RR L IC     R  +E C L     +   LV+   + EA
Sbjct: 679 FEDDAIQLVARKVAALSGDARRCLDIC-----RRATEICELSHLRGDSLSLVTVAHLMEA 733

Query: 646 IRELTPSSVQSAVKQLSQIEQQVLMSAALCGRQAVQQGSETFRFQQIWHRFRQFHASTEG 705
           I E+  SS  +A+K  S +EQ  L +     R++   G E   FQQI+ +        EG
Sbjct: 734 IDEMFSSSYITAIKNSSVVEQSFLRAIIAEFRRS---GLEEATFQQIYSQHVAL-CRMEG 789

Query: 706 HPAYPLPLQDQIEEVWHILMGLCACNLL 733
            P YP      + E   +   L +C LL
Sbjct: 790 LP-YP-----TMSETMAVCSRLGSCRLL 811

ref|NP_035145.1| origin recognition complex, subunit 1 isoform A [Mus musculus]
gb|AAH15073.1| Origin recognition complex, subunit 1 [Mus musculus]
sp|Q9Z1N2|ORC1_MOUSE Origin recognition complex subunit 1
emb|CAA05890.1| ORC1-related protein [Mus musculus]
(840 aa)

Score: 171 bits (434), Expect: 6.92261e-41
Length: 388, Idn/Pos/Gap = 134/202/38 (34%/52%/9%)

Query: 348 VSEPTGSVPRLLQVSRFGAPRVQLVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGK 407
           V EP  ++          A    L CR+ E + +  F+   L   +  C+YISGVPGTGK
Sbjct: 460 VQEPASALEEARLRLHVSAVPDSLPCREQEFQDIYSFVESKLLDGTGGCMYISGVPGTGK 519

Query: 408 TAVVRCAVQQLEQRRQQGQVPHFQYIEINGMTIPDPTRAYNILLQRL-GHRSTGAAGGRR 466
           TA V   ++ L+Q  +   VP FQY+E+NGM + +P + Y  +L++L G ++T       
Sbjct: 520 TATVHEVIRCLQQAAETDDVPPFQYVEVNGMKLTEPHQVYVQILKKLTGQKATA------ 573

Query: 467 PPAPAEAARLLDQRFRQRRGVHNRKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWAS 526
                 AA LL ++F        +       VLL +   L+  H    Q V+Y+  DW +
Sbjct: 574 ----NHAAELLAKQF------CGQGSQKETTVLLVDELDLLWTHK---QDVMYNLFDWPT 620

Query: 527 RPASELVIIGIANTLDLPER-LLPRLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQH 585
              + L+++ IANT+DLPER ++ R++SRLG+ R  F+PYS +QL+QIL  +L  + L+ 
Sbjct: 621 HKGAHLIVLTIANTMDLPERIMMNRVSSRLGLTRMSFQPYSHSQLKQILVSRL--RNLRA 678

Query: 586 FDEDALELCTRRVAAVSGDIRRALAICLHAYARSHSEDCSLRASENEHDRLVSAVDIDEA 645
           F++DA++L  R+VAA+SGD RR L IC     R  +E C L     +   LV+   + EA
Sbjct: 679 FEDDAIQLVARKVAALSGDARRCLDIC-----RRATEICELSHLRGDSLSLVTVAHLMEA 733

Query: 646 IRELTPSSVQSAVKQLSQIEQQVLMSAALCGRQAVQQGSETFRFQQIWHRFRQFHASTEG 705
           I E+  SS  +A+K  S +EQ  L +     R++   G E   FQQI+ +        EG
Sbjct: 734 IDEMFSSSYITAIKNSSVVEQSFLRAIIAEFRRS---GLEEATFQQIYSQHVAL-CRMEG 789

Query: 706 HPAYPLPLQDQIEEVWHILMGLCACNLL 733
            P YP      + E   +   L +C LL
Sbjct: 790 LP-YP-----TMSETMAVCSRLGSCRLL 811

gb|AAH38007.1| Orc1l protein [Mus musculus]
(840 aa)

Score: 169 bits (429), Expect: 2.42e-40
Length: 388, Idn/Pos/Gap = 134/202/38 (34%/52%/9%)

Query: 348 VSEPTGSVPRLLQVSRFGAPRVQLVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGK 407
           V EP  ++          A    L CR+ E + +  F+   L   +  C+YISGVPGTGK
Sbjct: 460 VQEPASALEEARLRLHVSAVPDSLPCREQEFQDIYSFVESKLLDGTGGCMYISGVPGTGK 519

Query: 408 TAVVRCAVQQLEQRRQQGQVPHFQYIEINGMTIPDPTRAYNILLQRL-GHRSTGAAGGRR 466
           TA V   ++ L+Q  +   VP FQY+E+NGM + +P + Y  +L++L G ++T       
Sbjct: 520 TATVHEVIRCLQQAAETDDVPPFQYVEVNGMKLTEPHQVYVQILKKLTGQKATA------ 573

Query: 467 PPAPAEAARLLDQRFRQRRGVHNRKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWAS 526
                 AA LL ++F        +       VLL +   L+  H    Q V+Y+  DW +
Sbjct: 574 ----NHAAELLAKQF------CGQGSQKETTVLLVDELDLLWTHK---QDVMYNLFDWPT 620

Query: 527 RPASELVIIGIANTLDLPER-LLPRLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQH 585
              + L+++ IANT+DLPER ++ R++SRLG+ R  F+PYS +QL+QIL  +L  + L+ 
Sbjct: 621 HKGAHLIVLTIANTMDLPERIMMNRVSSRLGLTRMSFQPYSHSQLKQILVSRL--RNLRA 678

Query: 586 FDEDALELCTRRVAAVSGDIRRALAICLHAYARSHSEDCSLRASENEHDRLVSAVDIDEA 645
           F++DA++L  R+VAA+SGD RR L IC     R  +E C L     +   LV+   + EA
Sbjct: 679 FEDDAIQLVARKVAALSGDARRCLDIC-----RRATEICELSHLRGDSLSLVTVAHLMEA 733

Query: 646 IRELTPSSVQSAVKQLSQIEQQVLMSAALCGRQAVQQGSETFRFQQIWHRFRQFHASTEG 705
           I E+  SS  +A+K  S +EQ  L +     R++   G E   FQQI+ +        EG
Sbjct: 734 IDEMFSSSYITAIKNSSVVEQSFLRAIIAEFRRS---GLEEATFQQIYSQHVAL-CRMEG 789

Query: 706 HPAYPLPLQDQIEEVWHILMGLCACNLL 733
            P YP      + E   +   L +C LL
Sbjct: 790 LP-YP-----TMSETMAVCSRLGSCRLL 811

ref|NP_001014918.1| origin recognition complex subunit 1 [Bos taurus]
gb|AAX46516.1| origin recognition complex, subunit 1 [Bos taurus]
(871 aa)

Score: 169 bits (429), Expect: 2.60873e-40
Length: 365, Idn/Pos/Gap = 128/192/38 (35%/52%/10%)

Query: 371 LVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHF 430
           L CR+ E + +  F+   L   +  C+YISGVPGTGKTA V   +  L+Q  Q  +VP F
Sbjct: 506 LPCREQEFQDIYNFVESKLLDQTGGCMYISGVPGTGKTATVHEVICCLQQAAQANEVPPF 565

Query: 431 QYIEINGMTIPDPTRAYNILLQRL-GHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHN 489
           QYIE+NGM + +P + Y  +LQ+L G R+T             AA LL +RF  +     
Sbjct: 566 QYIEVNGMKLTEPHQVYVQILQKLTGKRATA----------NHAAALLAKRFCTQ----- 610

Query: 490 RKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPER-LL 548
                S       +   +       Q V+Y+  +W +   + LV++ IANT+DLPER ++
Sbjct: 611 ----GSSQETTVLLVDELDLLWTQKQDVMYNLFEWPTHKEARLVVLTIANTMDLPERIMM 666

Query: 549 PRLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQHFDEDALELCTRRVAAVSGDIRRA 608
            R++SRLG+ R  F+PY+ +QL+QIL  +L  + ++ F++DA++L  R+VAA+SGD RR 
Sbjct: 667 NRVSSRLGLTRMCFQPYTHSQLRQILLSRL--RHVKAFEDDAIQLVARKVAALSGDARRC 724

Query: 609 LAICLHAYARSHSEDCSLRASENEHDRLVSAVDIDEAIRELTPSSVQSAVKQLSQIEQQV 668
           L IC     R  +E C     + +   LV+   + EAI E+  SS  +A+K  S +EQ  
Sbjct: 725 LDIC-----RRATEICEFSCQKPDSPGLVTTAHLLEAIDEMFSSSYITAIKNSSVLEQSF 779

Query: 669 LMSAALCGRQAVQQGSETFRFQQIWHRFRQFHASTEGHPAYPLPLQDQIEEVWHILMGLC 728
           L +     R++   G E   FQQ++ +        EG P YP      + E   +   L 
Sbjct: 780 LRAILAEFRRS---GLEEATFQQVYIQHVAL-CRMEGLP-YP-----TMSETMAVCSRLG 829

Query: 729 ACNLL 733
           AC LL
Sbjct: 830 ACRLL 834

emb|CAF94103.1| unnamed protein product [Tetraodon nigroviridis]
(884 aa)

Score: 169 bits (427), Expect: 3.76591e-40
Length: 329, Idn/Pos/Gap = 120/184/31 (36%/55%/9%)

Query: 371 LVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHF 430
           L CR+ E + +  F+   +   +  C+YISGVPGTGKTA V   ++ L+      Q+P F
Sbjct: 529 LPCREQEFQDIYSFVESKITDGTGGCMYISGVPGTGKTATVHEVIRCLQHAADADQIPPF 588

Query: 431 QYIEINGMTIPDPTRAYNILLQRL-GHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHN 489
            ++EINGM + +P +AY  +LQ+L G ++T             AA LL++RF +      
Sbjct: 589 TFVEINGMKMTEPHQAYVQVLQKLTGQKATA----------DHAAALLERRFSKPA---P 635

Query: 490 RKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPER-LL 548
           RK  + +LV   ++           Q V+Y+  DW +R  + LV++ IANT+DLPER ++
Sbjct: 636 RKETTVLLVDELDLLW------TRKQNVMYNLFDWPTRRHARLVVLTIANTMDLPERIMI 689

Query: 549 PRLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQHFDEDALELCTRRVAAVSGDIRRA 608
            R+ASRLG+ R  F+PY+  QLQQIL  +L    L+ F+EDAL+L +R+VAA+SGD RR 
Sbjct: 690 NRVASRLGLTRMSFQPYTFKQLQQILTSRLNK--LKAFEEDALQLVSRKVAALSGDARRC 747

Query: 609 LAICLHAYARSHSEDCSLRASENEHDRLVSAVDIDEAIRELTPSSVQSAVKQLSQIEQQV 668
           L IC     R  +E C   A       LV    + EA+ E+  S+  +A++  S +++Q+
Sbjct: 748 LDIC-----RRATEICEQAAGAAPAPGLVGMGHVMEALNEMFSSAYVAAIRSAS-LQEQL 801

Query: 669 LMSAALCGRQAVQQGSETFRFQQIWHRFR 697
            + A +   +  + G E   FQQ+  R R
Sbjct: 802 FLRAVIA--EFRRLGLEEATFQQVGGRNR 828

gb|EAL25977.1| GA10479-PA [Drosophila pseudoobscura]
(931 aa)

Score: 169 bits (427), Expect: 4.30376e-40
Length: 324, Idn/Pos/Gap = 110/180/32 (33%/55%/9%)

Query: 371 LVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHF 430
           L CR+ E E +  FL   ++     C+Y+SGVPGTGKTA V   ++ L++   Q ++  F
Sbjct: 577 LPCREKEFENIYSFLEGKIQDQCGGCMYVSGVPGTGKTATVTGVIRTLQRLVSQDKLADF 636

Query: 431 QYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHNR 490
            ++EINGM + +P +AY  + ++L  ++          +   A  LL++RF         
Sbjct: 637 DFLEINGMRLTEPRQAYVQIYKQLTGKTV---------SWEHAHTLLEKRF-----TTPA 682

Query: 491 KHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLL-P 549
               + ++L+DE+D L        Q V+Y+ LDW ++ A+ LV++ IANT+DLPERLL  
Sbjct: 683 PRRVTTVLLVDELDILCNRR----QDVVYNLLDWPTKSAARLVVVTIANTMDLPERLLMG 738

Query: 550 RLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQHFDEDALELCTRRVAAVSGDIRRAL 609
           ++ SRLG+ R  F+PY+  QLQ+I+  +LG    + F  +A++L  R+VAAVSGD RRAL
Sbjct: 739 KVTSRLGLTRLTFQPYTHKQLQEIVTARLGGS--EAFKGEAVQLVARKVAAVSGDARRAL 796

Query: 610 AICLHAYARSHSEDCSLRASENEHDRLVSAVDIDEAIRELTPSSVQSAVKQLSQIEQQVL 669
            IC  A             ++   D+ V+ + + +A+ E+  S+   A+K  S++EQ  L
Sbjct: 797 DICRRA----------TEIADTARDKCVTMLHVQQALGEMIASAKVQAIKNCSRLEQIFL 846

Query: 670 MS-AALCGRQAVQQGSETFRFQQI 692
            + AA   R  V++ +    + Q+
Sbjct: 847 QAVAAEVTRTGVEESTFMGVYTQV 870

dbj|BAD72454.1| putative origin recognition complex 1 [Oryza sativa (japonica cultivar-group)]
(814 aa)

Score: 164 bits (414), Expect: 1.27364e-38
Length: 283, Idn/Pos/Gap = 108/158/21 (38%/55%/7%)

Query: 371 LVCRDVETERVLKFLTD--CLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVP 428
           L CRD E E +  F+ D  C      RCLYI GVPGTGKT  V   +++L      G + 
Sbjct: 436 LPCRDKEMEEISAFVKDAICNDQCLGRCLYIHGVPGTGKTMSVLAVMRRLRSELDSGNLR 495

Query: 429 HFQYIEINGMTIPDPTRAYNILLQRL-GHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGV 487
            + +IEING+ +  P   Y ++ ++L GHR     G ++      A   L + F     +
Sbjct: 496 PYSFIEINGLKLASPENIYKVIYEQLSGHR----VGWKK------ALHYLTEHFSGGTKI 545

Query: 488 HNRKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERL 547
             + +   IL++ +    L  N     Q VLY+ LDW +RP S LV+IGIANT+DLPE+L
Sbjct: 546 GKQANQPIILLIDELDLLLTRN-----QSVLYNILDWPTRPNSNLVVIGIANTMDLPEKL 600

Query: 548 LPRLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQHFDEDALELCTRRVAAVSGDIRR 607
           LPR++SR+G+ R  F PY+  QLQ+I+  +L  + +  F++ A+E  +R+VAA+SGD RR
Sbjct: 601 LPRISSRMGIQRLCFGPYNYRQLQEIITSRL--KGIDAFEDQAIEFASRKVAAMSGDARR 658

Query: 608 ALAICLHAYARS-HSEDCSLRASENEHDRLVSAVDIDEAIREL 649
           AL IC  A   + +    S   S N    +V   DI+ AI+E+
Sbjct: 659 ALEICRRAAEFADYRVKQSGHTSVNRGKNVVCMGDIEAAIQEV 701

ref|XP_392056.1| similar to Origin recognition complex subunit 1 (DmORC1) [Apis mellifera]
(526 aa)

Score: 163 bits (413), Expect: 1.67737e-38
Length: 304, Idn/Pos/Gap = 104/169/38 (34%/55%/12%)

Query: 371 LVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHF 430
           L CR+ E   +  FL   L   S       GVPGTGKTA V  A++ L++   +GQ+  F
Sbjct: 178 LPCREEEFNNIFTFLRGKLEDKSG-----GGVPGTGKTATVNEAIRCLQKLILKGQLDDF 232

Query: 431 QYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHNR 490
            Y+ INGM + +P + Y  +L++L +++             ++  +L++RF      HN 
Sbjct: 233 DYVTINGMKLTEPRQGYVQILKQLYNKTA---------TWEQSYSILEKRF------HNT 277

Query: 491 KHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPER-LLP 549
               ++L L+DE+D L        Q V+Y+ LDW ++  ++L+++ IANT+DLPER L+ 
Sbjct: 278 NSKMTLL-LVDELDFLCTKR----QDVVYNLLDWPTKSTAQLIVVTIANTMDLPERVLMG 332

Query: 550 RLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQHFDEDALELCTRRVAAVSGDIRRAL 609
           R+ SRLG+ R  F+PY+  QLQ+I+  +L  +    F  +A++L  R+V+AVSGD RRAL
Sbjct: 333 RVTSRLGLTRLTFQPYNYKQLQEIVMSRL--KNFDGFRSEAIQLVARKVSAVSGDARRAL 390

Query: 610 AICLHAYARSHSEDCSLRASENEHDRLVSAVDIDEAIRELTPSSVQSAVKQLSQIEQQVL 669
            IC  A          +  +E+ +   +S  D+ EA+ E+  S+   A+K  S++EQ  L
Sbjct: 391 DICRRA----------IEIAESRNAETISLQDVTEAVSEMIASAKVQAIKHCSKMEQIFL 440

Query: 670 MSAA 673
            + +
Sbjct: 441 QAVS 444

gb|AAL10452.1| origin recognition complex subunit 1 [Zea mays]
(810 aa)

Score: 163 bits (412), Expect: 2.1725e-38
Length: 310, Idn/Pos/Gap = 110/169/26 (35%/54%/8%)

Query: 371 LVCRDVETERVLKFLTD--CLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVP 428
           L CRD E E +  F+ D  C      RCLYI GVPGTGKT  V   +++L      G + 
Sbjct: 427 LPCRDKEMEEISIFVKDAICNDQCLGRCLYIHGVPGTGKTMSVLAVMRRLRSEFDSGTLR 486

Query: 429 HFQYIEINGMTIPDPTRAYNILLQRL-GHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGV 487
            + +IEING+ +  P   Y ++ ++L GHR     G ++      A   L + F     +
Sbjct: 487 PYCFIEINGLKLASPENIYKVVYEQLSGHR----VGWKK------ALHYLTEHFSGGTKI 536

Query: 488 HNRKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERL 547
             + +   IL++ +    L  +     Q VLY+ LDW ++P S LV+IGIANT+DLPE+L
Sbjct: 537 GKQANQPIILLIDELDLLLTRD-----QSVLYNILDWPTKPYSNLVVIGIANTMDLPEKL 591

Query: 548 LPRLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQHFDEDALELCTRRVAAVSGDIRR 607
           LPR++SR+G+ R  F PY+  QLQ+I+  +L  + +  F+E A+E  +R+VAA+SGD RR
Sbjct: 592 LPRISSRMGIQRLCFGPYNYRQLQEIITSRL--KGIDAFEEQAIEFASRKVAAMSGDARR 649

Query: 608 ALAICLHA------YARSHSEDCSLRASENEHDRLVSAVDIDEAIRELTPSSVQSAVKQL 661
           AL IC  A        +   +      S N+ D +VS  DI+ AI+E+  +     +K  
Sbjct: 650 ALEICRRAAEFADYRVKQSRQSAQNTVSANKGDGVVSMGDIEAAIQEVFQAPHIQVMKNC 709

Query: 662 SQIEQQVLMS 671
            +  + +L++
Sbjct: 710 PKFGKVILVA 719

emb|CAG80833.1| unnamed protein product [Yarrowia lipolytica CLIB99]
ref|XP_502645.1| hypothetical protein [Yarrowia lipolytica]
(718 aa)

Score: 160 bits (406), Expect: 1.25293e-37
Length: 250, Idn/Pos/Gap = 95/148/25 (38%/59%/10%)

Query: 371 LVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHF 430
           L CR+ E   V   +   +R  S  C+++SG PG+GKTA VR  V QL+ R +  ++P F
Sbjct: 344 LPCRETEFSNVYLGIESAIRSGSGTCIFVSGTPGSGKTATVREVVSQLQIRVEDNEIPDF 403

Query: 431 QYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHNR 490
            ++E+NGM + +P   Y +L ++L       +G R   A   A +LL+ RF+Q      +
Sbjct: 404 LFVELNGMKLTNPHTTYELLWEQL-------SGERL--AYNNAIKLLEHRFQQ------K 448

Query: 491 KHHSSILVLLDEMDALV-LNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLLP 549
            + + ++V+LDE+D LV LN     Q V+Y+F +W + P S+L+++ IANT+DLPER L 
Sbjct: 449 SNDTPLVVVLDELDQLVTLN-----QSVMYNFFNWPTLPHSKLIVVAIANTMDLPERTLS 503

Query: 550 -RLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQH---FDEDALELCTRRVAAVSGDI 605
            +++SRLG+ R  F  Y+  QL+ I+  +LG            DA+E  +R++A+VSGD 
Sbjct: 504 NKISSRLGLTRIQFPGYTHEQLKLIIESRLGDIAESSGTVVRPDAIEFASRKIASVSGDA 563

Query: 606 RRALAICLHA 615
           RRAL +C  A
Sbjct: 564 RRALDLCRRA 573

dbj|BAA89785.2| origin recognition complex 1 [Oryza sativa (japonica cultivar-group)]
(812 aa)

Score: 160 bits (404), Expect: 1.74933e-37
Length: 283, Idn/Pos/Gap = 107/156/21 (37%/55%/7%)

Query: 371 LVCRDVETERVLKFLTD--CLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVP 428
           L CRD E E +  F+ D  C      RCLYI GVPGTGKT  V   +++L      G + 
Sbjct: 434 LPCRDKEMEEISAFVKDAICNDQCIGRCLYIHGVPGTGKTMSVLAVMRRLRSELDSGNLR 493

Query: 429 HFQYIEINGMTIPDPTRAYNILLQRL-GHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGV 487
            + +IEING+ +  P   Y ++ ++L GHR     G ++      A   L + F     +
Sbjct: 494 PYSFIEINGLKLASPENIYKVIYEQLSGHR----VGWKK------ALHYLTEHFSGGTKI 543

Query: 488 HNRKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERL 547
             + +   IL++ +    L  N     Q VLY+ LDW +RP S LV+IGIANT+DLPE+L
Sbjct: 544 GKQANQPIILLIDELDLLLTRN-----QSVLYNILDWPTRPNSNLVVIGIANTMDLPEKL 598

Query: 548 LPRLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQHFDEDALELCTRRVAAVSGDIRR 607
           L R++SR+G+ R  F PY+  QLQ+I+  +L  + +  F++ A+E  +R+VAA+SGD RR
Sbjct: 599 LLRISSRMGIQRLCFGPYNYRQLQEIITSRL--KGIDAFEDQAIEFASRKVAAMSGDARR 656

Query: 608 ALAICLHAYA-RSHSEDCSLRASENEHDRLVSAVDIDEAIREL 649
           AL IC  A     +    S   S N    +V   DI+ AI+E+
Sbjct: 657 ALEICRRAAEFADYRVKQSGHTSVNRGKNVVCMGDIEAAIQEV 699

gb|EAA10354.3| ENSANGP00000011420 [Anopheles gambiae str. PEST]
ref|XP_315055.2| ENSANGP00000011420 [Anopheles gambiae str. PEST]
(875 aa)

Score: 158 bits (400), Expect: 5.3959e-37
Length: 332, Idn/Pos/Gap = 108/183/29 (32%/55%/8%)

Query: 371 LVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHF 430
           L CR+ E E +  FL   +      C+YISGVPGTGKTA     ++ L+   ++  +P F
Sbjct: 515 LPCREKEYEEIYNFLEGKIFDGCGGCMYISGVPGTGKTATTTAVLRALKHLSEEEDIPKF 574

Query: 431 QYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHNR 490
           ++++INGM + +P +AY  + ++L  ++          A  +A  LL++RF  +      
Sbjct: 575 EFVDINGMRLTEPRQAYVHIYRQLTGKTL---------AWEQAYNLLNKRFTTK-----A 620

Query: 491 KHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLL-P 549
               + ++L+DE+D L        Q V+Y+ L+W + P ++L+++ IANT+DLPERLL  
Sbjct: 621 PRRITTVLLVDELDILC----NKRQDVVYNLLNWPTMPTAQLIVVTIANTMDLPERLLMG 676

Query: 550 RLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQHFDEDALELCTRRVAAVSGDIRRAL 609
           +++SRLG+ R  F+PY+  QLQ+I+  +L    +  F+ DA++L  R+VAAVSGD RRAL
Sbjct: 677 KISSRLGLTRLTFQPYNFRQLQEIVMARLVG--MSAFNSDAVQLVARKVAAVSGDARRAL 734

Query: 610 AICLHAYARSHSEDCSLRASENEHDRLVSAVDIDEAIRELTPSSVQSAVKQLSQIEQQVL 669
            IC     R  +E    +A ++     VS + + +A+ E+  S+    ++  S++EQ  L
Sbjct: 735 DIC-----RRATELADDQARKSNESVTVSMMHVQQALTEMITSAKVKTIRSCSRLEQLFL 789

Query: 670 MSAALCGRQAVQQGSETFRFQQIWHRFRQFHA 701
            +      +  + G E   F  ++ +F    A
Sbjct: 790 QAVT---AEVTRTGIEECNFLGVYSQFESLAA 818

gb|EAA70645.1| hypothetical protein FG01336.1 [Gibberella zeae PH-1]
ref|XP_381512.1| hypothetical protein FG01336.1 [Gibberella zeae PH-1]
(721 aa)

Score: 157 bits (396), Expect: 1.72088e-36
Length: 385, Idn/Pos/Gap = 122/194/42 (31%/50%/10%)

Query: 312 TPRPRAGGQLLLWPSDVGAHEHRQSRISKNA---VEFAEVSEPTGSVPRLLQVSRFGAPR 368
           TP     G +   P+   +     SRI ++A   +EF  ++    S P  ++ S F   R
Sbjct: 247 TPTKTGRGSVAATPTSRRSTATPGSRIKRSASKRLEFTPLATRKLS-PSQVESSPFQIAR 305

Query: 369 ---------VQLVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLE 419
                      L CR+ E   V   L   +   +  C+YISG PGTGKTA VR  V +LE
Sbjct: 306 SRLHVSSVPTSLPCREGEFSLVYSHLEAAISDGTGNCIYISGTPGTGKTATVREVVSRLE 365

Query: 420 QRRQQGQVPHFQYIEINGMTIPDPTRAYNILLQRL-GHRSTGAAGGRRPPAPAEAARLLD 478
           +     ++  F ++EINGM I DP ++Y +L + L G R++          PA+A  LL+
Sbjct: 366 ESVGSDELDDFIFVEINGMKITDPHQSYTLLWEALKGERAS----------PAQALDLLE 415

Query: 479 QRFRQRRGVHNRKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIA 538
           + F      +        +VL+DE+D LV  +    Q V+Y+F +W +   S L+++ +A
Sbjct: 416 REFS-----NPSPRRIPCVVLMDELDQLVTKN----QAVMYNFFNWPTLRHSRLIVLAVA 466

Query: 539 NTLDLPERLLP-RLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQHFDEDALELCTRR 597
           NT+DLPER L  +++SRLG+ R  F  Y+  QL +I++ +L        D DA++  +R+
Sbjct: 467 NTMDLPERTLSNKISSRLGLTRITFPGYNHEQLMRIIQSRLEGVPGNIVDPDAIQFASRK 526

Query: 598 VAAVSGDIRRALAICLHAYARSHSE---DCSLRASENEHDR-----LVSAVDIDEAIREL 649
           VAAVSGD RRAL IC  A   + ++   D S  +  +   +      V+   I +AI E 
Sbjct: 527 VAAVSGDARRALDICRRAVELAEADAPIDPSTPSKRDPQTQSKGSGRVTIATIKKAINEA 586

Query: 650 TPSSVQSAVKQLSQIEQQVLMSAAL 674
           T + +Q  ++ L  + + V+ +  L
Sbjct: 587 TTNPIQQHLRSLPLMSKLVMAALLL 611

gb|EAA65800.1| hypothetical protein AN1207.2 [Aspergillus nidulans FGSC A4]
ref|XP_405344.1| hypothetical protein AN1207.2 [Aspergillus nidulans FGSC A4]
(796 aa)

Score: 155 bits (392), Expect: 4.23744e-36
Length: 346, Idn/Pos/Gap = 116/175/48 (33%/50%/13%)

Query: 338 ISKNAVEFAEVSEPTGSVPRLLQVSRFGAPRVQ-------------LVCRDVETERVLKF 384
           I K  +EF     P G+  R+L  + F +P  Q             L CR  E + V   
Sbjct: 309 IVKKPLEFT----PLGT--RVLSPAHFASPYRQARNLLHVSAVPDSLPCRKKEFDTVYSH 362

Query: 385 LTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHFQYIEINGMTIPDPT 444
           L+  +   +  C+YISG PGTGKTA VR  V QL       ++  F ++EINGM + DP 
Sbjct: 363 LSAAIMEGTGTCIYISGTPGTGKTATVREVVAQLNAAVLAEEMDDFIFVEINGMKVTDPH 422

Query: 445 RAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHNRKHHSSILVLLDEMD 504
           ++Y++L + L        G R   +P+ A  LLD+ F      +      S +VL+DE+D
Sbjct: 423 QSYSLLWEAL-------KGDR--VSPSHALDLLDREFS-----NPSPRRVSCVVLMDELD 468

Query: 505 ALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLLP-RLASRLGMNRQVFK 563
            LV  +    Q V+Y+F +W +   S L+++ +ANT+DLPER L  +++SRLG+ R  F 
Sbjct: 469 QLVTKN----QSVMYNFFNWPALRHSRLIVLAVANTMDLPERTLSNKISSRLGLTRITFP 524

Query: 564 PYSVTQLQQILRHKLGPQLLQHFDEDALELCTRRVAAVSGDIRRALAICLHAYARSHSED 623
            Y  T L +I+  +L     +  D DA++  +R+VAAVSGD RRAL IC  A        
Sbjct: 525 GYKHTDLMEIITTRLASVPGKIVDSDAIQFASRKVAAVSGDARRALDICRRAVE------ 578

Query: 624 CSLRASENEHDRLVSAVDIDEAIRELTPSSVQSAVKQLSQIEQQVL 669
               A ++     V A+D D+    L P+  ++A ++     +Q L
Sbjct: 579 ---IAEQSNEAAGVEALDADDT-ESLPPTPSKTAARKERANAKQTL 620

gb|EAA54824.1| hypothetical protein MG05615.4 [Magnaporthe grisea 70-15]
ref|XP_360241.1| hypothetical protein MG05615.4 [Magnaporthe grisea 70-15]
(785 aa)

Score: 155 bits (391), Expect: 5.77004e-36
Length: 330, Idn/Pos/Gap = 116/172/39 (35%/52%/11%)

Query: 312 TPR-PRAGGQLLLWPSDVG--------AHEHRQSRISKNAVEFAEVSEPTGSVPRLLQVS 362
           TP+ PR G    + PS  G           HR+  + K+ +EF  ++  T S P   Q S
Sbjct: 268 TPKKPRTGLATAVTPSKGGRTPSKPATPSSHRRIVVKKH-LEFTPLATRTLS-PSHHQNS 325

Query: 363 RFGAPRVQL---------VCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRC 413
            F   R QL          CR+ E   V   L   +   +  C+YISG PGTGKTA VR 
Sbjct: 326 PFQIARAQLHVASVPTSLPCREAEFSEVYSHLEAAITDGTGSCIYISGTPGTGKTATVRE 385

Query: 414 AVQQLEQRRQQGQVPHFQYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEA 473
            V  L+   +  ++  F ++EINGM + DP +AY++L +        A  G+R  +PA+A
Sbjct: 386 VVASLDHAVRNDELDDFIFVEINGMKVSDPHQAYSLLWE--------ALKGQR-VSPAQA 436

Query: 474 ARLLDQRFRQRRGVHNRKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELV 533
             LL++ F      +        +VL+DE+D LV  +    Q V+Y+F +W     S L+
Sbjct: 437 LDLLEREFS-----NPSPRRVPCVVLMDELDQLVTKN----QGVMYNFFNWPGLRHSRLI 487

Query: 534 IIGIANTLDLPERLLP-RLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQHFDEDALE 592
           ++ +ANT+DLPER L  +++SRLG+ R  F  Y+  QL +I++ +L        D DA++
Sbjct: 488 VLAVANTMDLPERTLSNKISSRLGLTRITFPGYTHEQLMKIIQSRLEGVPGNIVDPDAIQ 547

Query: 593 LCTRRVAAVSGDIRRALAICLHAYARSHSE 622
             +R+VAAVSGD RRAL IC  A   + +E
Sbjct: 548 FASRKVAAVSGDARRALDICRRAVELAEAE 577

emb|CAE76259.1| related to origin recognition protein Orc1p [Neurospora crassa]
(766 aa)

Score: 154 bits (389), Expect: 1.00078e-35
Length: 314, Idn/Pos/Gap = 110/163/30 (35%/51%/9%)

Query: 312 TPRPRAGGQLLLWPSDVGAHEHRQSRISKNAVEFAEVSEPTGSVPRLLQVSRFGAPRVQL 371
           TP  R  G      + V    HR+  I ++ +EF  ++    S P  +  S +   R QL
Sbjct: 274 TPTSRRKGTKAALSAAVTPTSHRKIMIKRH-LEFTPLATRVLS-PMHIHNSPYQLARTQL 331

Query: 372 ---------VCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRR 422
                     CR+ E   V   L   +   S  C+YISG PGTGKTA VR  V  L+   
Sbjct: 332 HVASVPTSLPCREAEFSLVYSHLEAAITDGSGTCIYISGTPGTGKTATVREVVSHLDAAV 391

Query: 423 QQGQVPHFQYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFR 482
           +  ++  F ++EINGM I DP ++Y++L +        A  G+R  +P++A  LL++ F 
Sbjct: 392 RADELDDFIFVEINGMKITDPHQSYSLLWE--------ALKGQR-VSPSQALDLLEREFS 442

Query: 483 QRRGVHNRKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLD 542
                H        +VL+DE+D LV  +    Q V+Y+F +W     S L+++ +ANT+D
Sbjct: 443 -----HPSPRRVPCVVLMDELDQLVTKN----QGVMYNFFNWPGLRHSRLIVLAVANTMD 493

Query: 543 LPERLLP-RLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQHFDEDALELCTRRVAAV 601
           LPER L  +++SRLG+ R  F  Y+  QL +I++ +L        D DA++   R+VAAV
Sbjct: 494 LPERTLSNKISSRLGLTRITFPGYNHEQLMRIVQSRLEGVPGDIVDADAVQFAARKVAAV 553

Query: 602 SGDIRRALAICLHA 615
           SGD RRAL IC  A
Sbjct: 554 SGDARRALDICRRA 567

gb|EAL20422.1| hypothetical protein CNBE3430 [Cryptococcus neoformans var. neoformans B-3501A]
gb|AAW43603.1| replication control protein 1, putative [Cryptococcus neoformans var. neoformans JEC21]
ref|XP_570910.1| replication control protein 1, putative [Cryptococcus neoformans var. neoformans JEC21]
(711 aa)

Score: 153 bits (387), Expect: 1.87117e-35
Length: 271, Idn/Pos/Gap = 91/147/18 (33%/54%/6%)

Query: 351 PTGSVPRLLQVSRFGAPRVQLVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAV 410
           PT    R L++   GA    L CR+ E   VL  + + +      CLYI+GVPGTGKTA 
Sbjct: 285 PTDPFERALRMLHVGATPESLPCREEEFVDVLSKVEEGVESGGGGCLYIAGVPGTGKTAT 344

Query: 411 VRCAVQQLEQRRQQGQVPHFQYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAP 470
           V   V++L+++ + G++P F Y+EING+ IP P  AY +L + +   S+   G +     
Sbjct: 345 VHAVVKELKRKAEDGEIPPFSYVEINGLKIPAPQHAYTVLWEAIS--SSKGVGAK----- 397

Query: 471 AEAARLLDQRFRQRRGVHNRKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPAS 530
             A + L++ F ++ G        + +VL+DE+D L+     + Q V+Y+F +W +   S
Sbjct: 398 -TALKGLERHFGKKGGGARGPRGHTFVVLMDELDQLL----TSKQDVVYNFFNWPTMRDS 452

Query: 531 ELVIIGIANTLDLPERLLPRLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQHFDE-- 588
           +L +I +AN +DLP++L  ++ SRLG+   +F+PY    L  I++ +L P  L    +  
Sbjct: 453 QLFVIAVANRMDLPQQLAAKIKSRLGLQTILFEPYDRAALVSIVQSRLIPHPLMPSQDPK 512

Query: 589 ----DALELCTRRVAAVSGDIRRALAICLHA 615
               DA+ L   ++A  +GD RR L  C  A
Sbjct: 513 VLLPDAISLAAMKMAGTNGDARRVLDACRRA 543

ref|XP_330153.1| origin recognition complex subunit 1 homolog [MIPS] [Neurospora crassa]
gb|EAA36116.1| origin recognition complex subunit 1 homolog [MIPS] [Neurospora crassa]
pir||T50982 origin recognition complex subunit 1 homolog (ORC1) [imported] - Neurospora crassa
(468 aa)

Score: 153 bits (386), Expect: 2.56928e-35
Length: 246, Idn/Pos/Gap = 95/139/19 (38%/56%/7%)

Query: 371 LVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHF 430
           L CR+ E   V   L   +   S  C+YISG PGTGKTA VR  V  L+   +  ++  F
Sbjct:  42 LPCREAEFSLVYSHLEAAITDGSGTCIYISGTPGTGKTATVREVVSHLDAAVRADELDDF 101

Query: 431 QYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHNR 490
            ++EINGM I DP ++Y++L +        A  G+R  +P++A  LL++ F      H  
Sbjct: 102 IFVEINGMKITDPHQSYSLLWE--------ALKGQR-VSPSQALDLLEREFS-----HPS 147

Query: 491 KHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLLP- 549
                 +VL+DE+D LV  +    Q V+Y+F +W     S L+++ +ANT+DLPER L  
Sbjct: 148 PRRVPCVVLMDELDQLVTKN----QGVMYNFFNWPGLRHSRLIVLAVANTMDLPERTLSN 203

Query: 550 RLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQHFDEDALELCTRRVAAVSGDIRRAL 609
           +++SRLG+ R  F  Y+  QL +I++ +L        D DA++   R+VAAVSGD RRAL
Sbjct: 204 KISSRLGLTRITFPGYNHEQLMRIVQSRLEGVPGDIVDADAVQFAARKVAAVSGDARRAL 263

Query: 610 AICLHA 615
            IC  A
Sbjct: 264 DICRRA 269

gb|EAL02700.1| hypothetical protein CaO19.3000 [Candida albicans SC5314]
(805 aa)

Score: 150 bits (380), Expect: 1.2858e-34
Length: 345, Idn/Pos/Gap = 104/169/53 (30%/48%/15%)

Query: 396 CLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHFQYIEINGMTIPDPTRAYNILLQRLG 455
           C+Y+ GVPG GKTA ++  V+Q+    ++G++  F Y+E+NG+ +  PT AY  L   + 
Sbjct: 423 CVYVCGVPGMGKTATIKDVVEQMTYSSERGEMEQFSYLELNGLKLLSPTVAYEALWHHIS 482

Query: 456 HRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHNRKHHSSILVLLDEMDALVLNHSAAAQ 515
                A         + AA LL++ F  +R  H RK    +++L+DE D +    +   Q
Sbjct: 483 GDKVSA---------SNAALLLEEYF--KREDHKRK---PLVILMDEFDQI----ATKKQ 524

Query: 516 RVLYDFLDWASRPASELVIIGIANTLDLPERLLP-RLASRLGMNRQVFKPYSVTQLQQIL 574
            V+Y+F +W +   S+L++I +ANT+DLPER+L  ++ASRLG+ R  F+ Y+  QL  I+
Sbjct: 525 NVMYNFFNWPTYSTSKLIVIAVANTMDLPERMLTNKIASRLGLRRIQFRGYTFQQLGDII 584

Query: 575 RHKLGPQLLQH-------FDEDALELCTRRVAAVSGDIRRALAICLHAYARSHSEDCSLR 627
            H+L  +++            DA+   +R+VA+VSGD RRAL IC  A   +  E    +
Sbjct: 585 THRL--EMITKNNRRKVVITSDAIGFASRKVASVSGDARRALTICRRAVEIAEKEYLENK 642

Query: 628 ASENEHDRL-VSAVDIDEAIRELTPSSVQSAVKQLSQIEQQVLMSAALCGRQ-------- 678
             E++ +   V    I  AI E   S +   +  L    + VL S     R+        
Sbjct: 643 KGEDDSEPYQVLISHISTAINETVNSPLSKYIASLPFASKLVLASLLRRSRRTGLAENSL 702

Query: 679 ----------------AVQQGSETFRFQQIWHRFRQFHASTEGHP 707
                           + +QGS+    Q + +  + F A+ E  P
Sbjct: 703 GDIIDEMRNSFAMATHSEEQGSDELNMQDVLYSDKTFTATNETAP 747

emb|CAG87030.1| unnamed protein product [Debaryomyces hansenii CBS767]
ref|XP_458878.1| unnamed protein product [Debaryomyces hansenii]
sp|Q6BSE2|ORC1_DEBHA Origin recognition complex subunit 1
(810 aa)

Score: 150 bits (379), Expect: 1.32944e-34
Length: 317, Idn/Pos/Gap = 104/160/33 (32%/50%/10%)

Query: 371 LVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHF 430
           L CR+ E   +   L   ++  +  CLY+SG PG GKTA VR  + QL +  + G++  F
Sbjct: 393 LPCREDEFTSIYLNLETAIQEQTGCCLYVSGTPGVGKTATVREVIAQLRELTEMGELNDF 452

Query: 431 QYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHNR 490
            Y+EING+ +  P  AY  L +++      A         + AA LL+  F Q       
Sbjct: 453 DYLEINGLKLLSPNVAYEKLWEKISGLKVTA---------SNAALLLESYFSQ------D 497

Query: 491 KHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLLP- 549
                ++VL+DE+D +V       Q V+Y+F +W +   S+L++I +ANT+DLPER+L  
Sbjct: 498 TPRKPLIVLMDELDQIV----TKKQNVMYNFFNWPTYSNSKLIVIAVANTMDLPERVLSN 553

Query: 550 RLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQH-----FDEDALELCTRRVAAVSGD 604
           +++SRLG+ R  F  Y+  QL  I++H+L     Q+      + DA+   +R+VA+VSGD
Sbjct: 554 KISSRLGLRRIQFIGYTFEQLGSIIKHRLDMLTKQNKRKVIINSDAIGFASRKVASVSGD 613

Query: 605 IRRALAICLHA-------YARSHSEDCSLRASENEHDRLVSAVDIDEAIRELTPSSVQSA 657
            RRAL IC  A       +  S  +  + +  ENE    V    I +AI E   S +   
Sbjct: 614 ARRALTICRRAVEIAEKDFLSSKEDPGNEQEIENESYH-VQISHISKAINETVNSPISQF 672

Query: 658 VKQLSQIEQQVLMSAAL 674
           +  L    + VL    L
Sbjct: 673 LMSLPFASKLVLAGVLL 689

gb|EAL02420.1| hypothetical protein CaO19.10518 [Candida albicans SC5314]
(805 aa)

Score: 150 bits (379), Expect: 1.32944e-34
Length: 345, Idn/Pos/Gap = 104/169/53 (30%/48%/15%)

Query: 396 CLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHFQYIEINGMTIPDPTRAYNILLQRLG 455
           C+Y+ GVPG GKTA ++  V+Q+    ++G++  F Y+E+NG+ +  PT AY  L   + 
Sbjct: 423 CVYVCGVPGMGKTATIKDVVEQMTYSSERGEMEQFSYLELNGLKLLSPTVAYEALWHHIS 482

Query: 456 HRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHNRKHHSSILVLLDEMDALVLNHSAAAQ 515
                A         + AA LL++ F  +R  H RK    +++L+DE D +    +   Q
Sbjct: 483 GDKVSA---------SNAALLLEEYF--KREDHKRK---PLVILMDEFDQI----ATKKQ 524

Query: 516 RVLYDFLDWASRPASELVIIGIANTLDLPERLLP-RLASRLGMNRQVFKPYSVTQLQQIL 574
            V+Y+F +W +   S+L++I +ANT+DLPER+L  ++ASRLG+ R  F+ Y+  QL  I+
Sbjct: 525 NVMYNFFNWPTYSTSKLIVIAVANTMDLPERMLTNKIASRLGLRRIQFRGYTFQQLGDII 584

Query: 575 RHKLGPQLLQH-------FDEDALELCTRRVAAVSGDIRRALAICLHAYARSHSEDCSLR 627
            H+L  +++            DA+   +R+VA+VSGD RRAL IC  A   +  E    +
Sbjct: 585 THRL--EMITKNNRRKVVITSDAIGFASRKVASVSGDARRALTICRRAVEIAEKEYLENK 642

Query: 628 ASENEHDRL-VSAVDIDEAIRELTPSSVQSAVKQLSQIEQQVLMSAALCGRQ-------- 678
             E++ +   V    I  AI E   S +   +  L    + VL S     R+        
Sbjct: 643 KGEDDSEPYQVLISHISTAINETVNSPLSKYIASLPFASKLVLASLLRRSRRTGLAENSL 702

Query: 679 ----------------AVQQGSETFRFQQIWHRFRQFHASTEGHP 707
                           + +QGS+    Q + +  + F A+ E  P
Sbjct: 703 GDIIDEMRNSFAMATHSEEQGSDELNMQDVLYSDKTFTATNETAP 747

emb|CAA76762.1| origin recognition complex 1 protein [Candida albicans]
sp|O74270|ORC1_CANAL Origin recognition complex subunit 1
(805 aa)

Score: 149 bits (376), Expect: 3.52887e-34
Length: 345, Idn/Pos/Gap = 103/169/53 (29%/48%/15%)

Query: 396 CLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHFQYIEINGMTIPDPTRAYNILLQRLG 455
           C+Y+ G+PG GKTA ++  V+Q+    ++G++  F Y+E+NG+ +  PT AY  L   + 
Sbjct: 423 CVYVCGLPGMGKTATIKDVVEQMTYSSERGEMEQFSYLELNGLKLLSPTVAYEALWHHIS 482

Query: 456 HRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHNRKHHSSILVLLDEMDALVLNHSAAAQ 515
                A         + AA LL++ F  +R  H RK    +++L+DE D +    +   Q
Sbjct: 483 GDKVSA---------SNAALLLEEYF--KREDHKRK---PLVILMDEFDQI----ATKKQ 524

Query: 516 RVLYDFLDWASRPASELVIIGIANTLDLPERLLP-RLASRLGMNRQVFKPYSVTQLQQIL 574
            V+Y+F +W +   S+L++I +ANT+DLPER+L  ++ASRLG+ R  F+ Y+  QL  I+
Sbjct: 525 NVMYNFFNWPTYSTSKLIVIAVANTMDLPERMLTNKIASRLGLRRIQFRGYTFQQLGDII 584

Query: 575 RHKLGPQLLQH-------FDEDALELCTRRVAAVSGDIRRALAICLHAYARSHSEDCSLR 627
            H+L  +++            DA+   +R+VA+VSGD RRAL IC  A   +  E    +
Sbjct: 585 THRL--EMITKNNRRKVVITSDAIGFASRKVASVSGDARRALTICRRAVEIAEKEYLENK 642

Query: 628 ASENEHDRL-VSAVDIDEAIRELTPSSVQSAVKQLSQIEQQVLMSAALCGRQ-------- 678
             E++ +   V    I  AI E   S +   +  L    + VL S     R+        
Sbjct: 643 KGEDDSEPYQVLISHISTAINETVNSPLSKYIASLPFASKLVLASLLRRSRRTGLAENSL 702

Query: 679 ----------------AVQQGSETFRFQQIWHRFRQFHASTEGHP 707
                           + +QGS+    Q + +  + F A+ E  P
Sbjct: 703 GDIIDEMRNSFAMATHSEEQGSDELNMQDVLYSDKTFTATNETVP 747

gb|EAK86910.1| hypothetical protein UM06087.1 [Ustilago maydis 521]
ref|XP_403702.1| hypothetical protein UM06087.1 [Ustilago maydis 521]
(980 aa)

Score: 141 bits (355), Expect: 8.84074e-32
Length: 327, Idn/Pos/Gap = 103/166/41 (31%/50%/12%)

Query: 315 PRAGGQLLLWPSDVGAHEHRQSRISKNAVEFAEVSEPTGSVPRLLQVSRFGAPRVQLVCR 374
           PR+  +L+   +    H    +R  K ++  ++ ++   +  R  ++   GA    L CR
Sbjct: 509 PRSKARLMGLKARSLPHPTLPARPPKLSLLPSQEAQTLSAHDRAKRLLHVGATPDHLPCR 568

Query: 375 DVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHFQYIE 434
           + + E ++  + D +      C+Y+SGVPGTGKTA VR  ++ L  R ++ ++  F ++E
Sbjct: 569 EDQYEEIMACVEDAVEEGIGGCVYVSGVPGTGKTATVREVIRALTARAERNEMNPFSFVE 628

Query: 435 INGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQ----------R 484
           INGM + D ++AY +L        +  +GG+R  +P  A  LL   F +           
Sbjct: 629 INGMKLADASQAYTLLW-------SAISGGQR-TSPKTALGLLSSHFARVGAKMSGAAGG 680

Query: 485 RGVHNRKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLP 544
            GV      ++ +VL+DE+D LV     A Q V+Y+  +W +   S LV+I +ANT+DLP
Sbjct: 681 AGVGAGPGRAATVVLMDELDQLV----TARQDVMYNMFNWPNTRGSRLVVIAVANTMDLP 736

Query: 545 ERLL-PRLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQHFDE--------------- 588
           ER L  ++ASRLGM R  F PY+  QL +I++ +LG    +  D                
Sbjct: 737 ERTLNAKVASRLGMTRITFMPYTDRQLVEIVKSRLGICSQETDDSAVVDKASIDNGCSKV 796

Query: 589 ---DALELCTRRVAAVSGDIRRALAIC 612
              DA+    +RV+ VSGD RR L +C
Sbjct: 797 LSLDAITYVGKRVSNVSGDARRMLDVC 823

emb|CAH80805.1| origin recognition complex 1 protein, putative [Plasmodium chabaudi]
(360 aa)

Score: 137 bits (345), Expect: 1.48348e-30
Length: 235, Idn/Pos/Gap = 78/128/32 (33%/54%/13%)

Query: 416 QQLEQRRQQGQVPHFQYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAAR 475
           Q L+ +  +  +P F   EINGM +  P  AY +  ++L +         +PP    + +
Sbjct:   1 QLLKNKSNKKLLPPFNVYEINGMNVVHPNAAYQVFYKQLFNS--------KPPNALNSFK  52

Query: 476 LLDQRFRQRRGVHNRKHHSSILVLL-DEMDALVLNHSAAAQRVLYDFLDWASRPASELVI 534
           ++D+ F +     N+K + ++ +L+ DE+D L+       Q+VL+   DW ++  S+L++
Sbjct:  53 IIDRLFNK-----NKKDNRNVSILIIDEIDYLI----TKTQKVLFTLFDWPTKVNSKLIL 103

Query: 535 IGIANTLDLPERLLPRLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQHFDEDALELC 594
           I I+NT+DLPERL+PR  SRL   R VF PY   ++++I++ +L        D  A++LC
Sbjct: 104 IAISNTMDLPERLIPRCRSRLAFGRLVFSPYKGDEIEKIIKERLD-NCKDIIDHTAIQLC 162

Query: 595 TRRVAAVSGDIRRALAICLHAYARSHSEDCSLRASENEHDRLVSAVDIDEAIREL 649
            R+VA VSGDIR+AL IC  A+             EN+  + +   DI EA  +L
Sbjct: 163 ARKVANVSGDIRKALQICRKAF-------------ENKRGQKIVPRDIIEATNQL 204

ref|NP_999666.1| cell division control protein 6 [Strongylocentrotus purpuratus]
gb|AAL37208.1| cell division control protein 6 [Strongylocentrotus purpuratus]
(582 aa)

Score: 133 bits (334), Expect: 2.40756e-29
Length: 252, Idn/Pos/Gap = 89/138/29 (35%/54%/11%)

Query: 370 QLVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPH 429
           +L+CR+ ET+ +  FL + L       LYISG PGTGKTA ++  +QQ +  R+     +
Sbjct: 164 RLLCREKETQTIQSFLKNHLEARKPGSLYISGAPGTGKTACLKQILQQQKSSRR-----N 218

Query: 430 FQYIEINGMTIPDPTRAYNILLQRLGHR-STGAAGGRRPPAPAEAARLLDQRFRQRRGVH 488
            Q+I +N M +      YN +L+ +    ST     +       AA+ L + F       
Sbjct: 219 TQHIFVNCMLVRQSQGIYNTVLKEVKQDVSTDKLSAKM------AAKALQKAFAS----- 267

Query: 489 NRKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLL 548
              +  ++L++LDE+D L     +  Q VLY   +W S P S LV++G+AN+LDL +R+L
Sbjct: 268 ---NGPTVLLVLDEIDHL----DSKGQEVLYTMFEWPSLPKSRLVLVGVANSLDLTDRIL 320

Query: 549 PRLASRLGMNRQV--FKPYSVTQLQQILRHKLGPQLLQH---FDEDALELCTRRVAAVSG 603
           PRL SR     ++  F PY+ TQ+  IL+ +L    +      D  A++LC R+VAAV+G
Sbjct: 321 PRLQSRPKCRPELLHFAPYTRTQISTILQDRLKESTVDGTAVVDPMAVQLCARKVAAVAG 380

Query: 604 DIRRALAICLHA 615
           D+R+AL +C  A
Sbjct: 381 DVRKALDVCRRA 392

ref|XP_513408.1| PREDICTED: similar to origin recognition complex, subunit 1; origin recognition complex, subunit 1, S. cerevisiae, homolog-like; origin recognition complex 1; replication control protein 1; origin recognition complex, subunit 1 (yeast homolog)-like ... [Pan troglodytes]
(762 aa)

Score: 133 bits (334), Expect: 2.42773e-29
Length: 233, Idn/Pos/Gap = 90/136/24 (38%/58%/10%)

Query: 371 LVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHF 430
           L CR+ E + +  F+   L   +  C+YISGVPGTGKTA V   ++ L+Q  Q   VP F
Sbjct: 502 LPCREQEFQDIYNFVESKLLDHTGGCMYISGVPGTGKTATVHEVIRCLQQAAQANDVPPF 561

Query: 431 QYIEINGMTIPDPTRAYNILLQRL-GHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHN 489
           QYIE+NGM + +P + Y  +LQ+L G ++T             AA LL ++F        
Sbjct: 562 QYIEVNGMKLTEPHQVYVQILQKLTGQKATA----------NHAAELLAKQF------CT 605

Query: 490 RKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPER-LL 548
           R       VLL +   L+  H    Q ++Y+  DW +   + LV++ IANT+DLPER ++
Sbjct: 606 RGSPQETTVLLVDELDLLWTHK---QDIMYNLFDWPTHKEARLVVLTIANTMDLPERIMM 662

Query: 549 PRLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQHFDEDALEL-CTRRVAA 600
            R++SRLG+ R  F+PY+ +QLQQILR +L  + L+ F++DA++L C+  + A
Sbjct: 663 NRVSSRLGLTRMCFQPYTYSQLQQILRSRL--KHLKAFEDDAIQLECSGTIMA 713

emb|CAG62232.1| unnamed protein product [Candida glabrata CBS138]
ref|XP_449258.1| unnamed protein product [Candida glabrata]
(1017 aa)

Score: 133 bits (334), Expect: 2.55237e-29
Length: 279, Idn/Pos/Gap = 88/140/51 (31%/50%/18%)

Query: 370 QLVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPH 429
            L  R+ E   +   +   +   S   +YI+G PG GKT  VR  +  L+    QG++P 
Sbjct: 567 HLPARENEFASIYLSVYSAIESGSATTVYIAGTPGVGKTLTVREVISDLQAASLQGELPK 626

Query: 430 FQYIEINGMTIPDPTRAYNILLQRL-GHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVH 488
           FQY+EING+ +  PT +Y     ++ G   T AA             +    F   +   
Sbjct: 627 FQYVEINGLKMVKPTDSYEFFWNKISGEELTWAAA------------MESLEFYFNKVPK 674

Query: 489 NRKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLL 548
           N+K    I+VLLDE+DALV      +Q V+Y+F +W++   ++LV+I +ANT+DLPE+ L
Sbjct: 675 NKKR--PIVVLLDELDALV----TKSQDVMYNFFNWSTYENAKLVVISVANTMDLPEKQL 728

Query: 549 -PRLASRLGMNRQVFKPYSVTQLQQILRHKL---------------GPQLLQ-------- 584
             +++SR+G  R +F  YS  +L+ I++ +L                 +L +        
Sbjct: 729 GNKVSSRIGFTRIMFTGYSHEELKTIIKFRLRGLNNSSFYVDPKTGNAKLAEATSNENVP 788

Query: 585 --------HFDEDALELCTRRVAAVSGDIRRALAICLHA 615
                      +DA+E+ +R+VA+VSGD RRAL +C  A
Sbjct: 789 EGMLKVRLKMTDDAIEIASRKVASVSGDARRALKVCKRA 827

emb|CAH02150.1| ORC1_KLULA [Kluyveromyces lactis NRRL Y-1140]
ref|XP_451757.1| ORC1_KLULA [Kluyveromyces lactis]
sp|P54788|ORC1_KLULA Origin recognition complex subunit 1
(886 aa)

Score: 131 bits (329), Expect: 1.03685e-28
Length: 396, Idn/Pos/Gap = 111/180/78 (28%/45%/19%)

Query: 327 DVGAHEHRQSRIS-KNAVE--FAEVSEPTGSVPRLLQVSRFGAPRVQLVCRDVETERVLK 383
           D+ A E R   +S K  +E  F++V +   S     ++ +       L  R+ E   +  
Sbjct: 394 DIAALEERFRTVSAKGKMETIFSKVKKQLNSRNSKEEIVKAADFDNYLPARENEFASIYL 453

Query: 384 FLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHFQYIEINGMTIPDP 443
            L   +   +   +YI+G PG GKT  VR  V+ L     Q ++P FQYIEING+ I   
Sbjct: 454 SLYSAIEAGTSTSIYIAGTPGVGKTLTVREVVKDLMTSADQKELPRFQYIEINGLKIVKA 513

Query: 444 TRAYNILLQRL-GHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHNRKHHSSILVLLDE 502
           + +Y +  Q++ G + T  A          A   L+  F +      R     I+VLLDE
Sbjct: 514 SDSYEVFWQKISGEKLTSGA----------AMESLEFYFNKVPATKKR----PIVVLLDE 559

Query: 503 MDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLL-PRLASRLGMNRQV 561
           +DALV    + +Q V+Y+F +WA+   ++L+++ +ANTLDLPER L  +++SR+G  R +
Sbjct: 560 LDALV----SKSQDVMYNFFNWATYSNAKLIVVAVANTLDLPERHLGNKISSRIGFTRIM 615

Query: 562 FKPYSVTQLQQILRHKLG----------------------------------------PQ 581
           F  Y+  +L+ I+  +L                                          +
Sbjct: 616 FTGYTHEELRTIINLRLKYLNESSFYVDPETGSSYMISPDSSTIETDEEEKRKDFSNYKR 675

Query: 582 LLQHFDEDALELCTRRVAAVSGDIRRALAICLHA-------------YAR--SHSEDCSL 626
           L    + DA+E+ +R++A+VSGD+RRAL +   A             Y R  +  +D S 
Sbjct: 676 LKLRINPDAIEIASRKIASVSGDVRRALKVVKRAVEYAENDYLKRLRYERLVNSKKDTSG 735

Query: 627 RASENEHDRLVSAVDIDEAIRELTPSSVQSAVKQLS 662
             + NE  + V    I +A+ E + S  Q  +  LS
Sbjct: 736 NGTGNEELQSVEIKHITKALNESSTSPEQQFISGLS 771

gb|AAC49130.1| KlORC1
(886 aa)

Score: 131 bits (329), Expect: 1.04554e-28
Length: 396, Idn/Pos/Gap = 111/180/78 (28%/45%/19%)

Query: 327 DVGAHEHRQSRIS-KNAVE--FAEVSEPTGSVPRLLQVSRFGAPRVQLVCRDVETERVLK 383
           D+ A E R   +S K  +E  F++V +   S     ++ +       L  R+ E   +  
Sbjct: 394 DIAALEERFRTVSAKGKMETIFSKVKKQLNSRNSKEEIVKAADFDNYLPARENEFASIYL 453

Query: 384 FLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHFQYIEINGMTIPDP 443
            L   +   +   +YI+G PG GKT  VR  V+ L     Q ++P FQYIEING+ I   
Sbjct: 454 SLYSAIEAGTSTSIYIAGTPGVGKTLTVREVVKDLMTSADQKELPRFQYIEINGLKIVKA 513

Query: 444 TRAYNILLQRL-GHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHNRKHHSSILVLLDE 502
           + +Y +  Q++ G + T  A          A   L+  F +      R     I+VLLDE
Sbjct: 514 SDSYEVFWQKISGEKLTSGA----------AMESLEFYFNKVPATKKR----PIVVLLDE 559

Query: 503 MDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLL-PRLASRLGMNRQV 561
           +DALV    + +Q V+Y+F +WA+   ++L+++ +ANTLDLPER L  +++SR+G  R +
Sbjct: 560 LDALV----SKSQDVMYNFFNWATYSNAKLIVVAVANTLDLPERHLGNKISSRIGFTRIM 615

Query: 562 FKPYSVTQLQQILRHKLG----------------------------------------PQ 581
           F  Y+  +L+ I+  +L                                          +
Sbjct: 616 FTGYTHEELRTIINLRLKYLNESSFYVDPETGSSYMISPDSSTIETDEEEKRKDFSNYKR 675

Query: 582 LLQHFDEDALELCTRRVAAVSGDIRRALAICLHA-------------YAR--SHSEDCSL 626
           L    + DA+E+ +R++A+VSGD+RRAL +   A             Y R  +  +D S 
Sbjct: 676 LKLRINPDAIEIASRKIASVSGDVRRALKVVKRAVEYAENDYLKRLRYERLVNSKKDTSG 735

Query: 627 RASENEHDRLVSAVDIDEAIRELTPSSVQSAVKQLS 662
             + NE  + V    I +A+ E + S  Q  +  LS
Sbjct: 736 NGTGNEELQSVEIKHITKALNESSTSPEQQFISGLS 771

emb|CAA21023.1| Hypothetical protein Y39A1A.12 [Caenorhabditis elegans]
ref|NP_499347.1| origin recognition complex (72.1 kD) (3L735) [Caenorhabditis elegans]
pir||T26734 hypothetical protein Y39A1A.12 - Caenorhabditis elegans
(636 aa)

Score: 129 bits (323), Expect: 4.24728e-28
Length: 286, Idn/Pos/Gap = 101/156/29 (35%/54%/10%)

Query: 335 QSRISKNAVEFAEVSEP--TGSVPRLLQV-SRFGAPRV--QLVCRDVETERVLKFLTDCL 389
           + R  +N+ E  ++ +P  + S   L ++ SR    +V  +L CRD+E+  + KF+ + +
Sbjct: 226 RRRARQNSEELEDLVDPLDSRSASTLKELASRLHLSKVPEKLPCRDIESREIEKFIREVI 285

Query: 390 ---RGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHFQYIEINGMTIPDPTRA 446
              RG S   +YISGVPGTGKTA VR  V  +++ ++      F Y+E+N M        
Sbjct: 286 DPKRGESS-AMYISGVPGTGKTATVRAVVNSMKKSKK---CQKFVYVEVNAMIFKKTV-- 339

Query: 447 YNILLQRLGHRSTGAAGGRRPPAPAEAARL-LDQRFRQRRGVHNRKHHSSILVLLDEMDA 505
           +  +   +      +   +R    A AAR  L+  F++            I+VL+DE+D+
Sbjct: 340 FVEIYNGIQEEYNISKKPQRAKITATAARQELNSIFKRED-----PKRPPIVVLIDELDS 394

Query: 506 LVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLL-PRLASRLGMNRQVFKP 564
           L        Q VLYD  +W + P S++ IIGIANTLD PER+L  R ASRL   R VF+P
Sbjct: 395 LC----NRKQDVLYDIFEWTALPQSKVTIIGIANTLDFPERMLCQRNASRLDKRRLVFQP 450

Query: 565 YSVTQLQQILRHKL-GPQLLQHFDEDALELCTRRVAAVSGDIRRAL 609
           Y   Q+++I+R +L G  L+   D  A+EL  ++VA  +GD+R+AL
Sbjct: 451 YQHEQIEEIVRARLQGSNLI---DPKAVELVAKKVAMNTGDLRQAL 493

emb|CAA86256.1| unnamed protein product [Saccharomyces cerevisiae]
gb|AAB38248.1| Orc1p [Saccharomyces cerevisiae]
ref|NP_013646.1| Largest subunit of the origin recognition complex, which directs DNA replication by binding to replication origins and is also involved in transcriptional silencing; may be phosphorylated by Cdc28p [Saccharomyces cerevisiae]
pir||S48333 ORC1 protein - yeast (Saccharomyces cerevisiae)
sp|P54784|ORC1_YEAST Origin recognition complex subunit 1 (Origin recognition complex protein 120 kDa subunit)
(914 aa)

Score: 127 bits (320), Expect: 9.46196e-28
Length: 265, Idn/Pos/Gap = 86/134/56 (32%/50%/21%)

Query: 389 LRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHFQYIEINGMTIPDPTRAYN 448
           +   S   +Y++G PG GKT  VR  V++L     Q ++P F Y+EING+ +  PT  Y 
Sbjct: 467 IESDSATTIYVAGTPGVGKTLTVREVVKELLSSSAQREIPDFLYVEINGLKMVKPTDCYE 526

Query: 449 ILLQRL-GHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHNRKHHSSILVLLDEMDALV 507
            L  ++ G R T AA             +    F  +R   N+K   +I+VLLDE+DA+V
Sbjct: 527 TLWNKVSGERLTWAAS------------MESLEFYFKRVPKNKK--KTIVVLLDELDAMV 572

Query: 508 LNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLL-PRLASRLGMNRQVFKPYS 566
                 +Q ++Y+F +W +   ++L++I +ANT+DLPER L  ++ SR+G  R +F  Y+
Sbjct: 573 ----TKSQDIMYNFFNWTTYENAKLIVIAVANTMDLPERQLGNKITSRIGFTRIMFTGYT 628

Query: 567 VTQLQQILRHKL--------------GPQLL-----------QHFDE-----------DA 590
             +L+ I+  +L              G  +L           Q   E           DA
Sbjct: 629 HEELKNIIDLRLKGLNDSFFYVDTKTGNAILIDAAGNDTTVKQTLPEDVRKVRLRMSADA 688

Query: 591 LELCTRRVAAVSGDIRRALAICLHA 615
           +E+ +R+VA+VSGD RRAL +C  A
Sbjct: 689 IEIASRKVASVSGDARRALKVCKRA 713

emb|CAE71424.1| Hypothetical protein CBG18335 [Caenorhabditis briggsae]
(682 aa)

Score: 127 bits (319), Expect: 1.36591e-27
Length: 287, Idn/Pos/Gap = 98/157/30 (34%/54%/10%)

Query: 335 QSRISKNAVEFAEVSEP--TGSVPRLLQV-SRFGAPRV--QLVCRDVETERVLKFLTDCL 389
           + R+ +N+ E  +V +P  + S   L ++ SR    +V  QL CR+ E   +  F+ + +
Sbjct: 271 RRRMRQNSEELDDVVDPLDSNSAKTLKELASRLHLSKVPEQLPCREAEAREIESFIREVI 330

Query: 390 ---RGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHFQYIEINGMTIPDP--T 444
              RG S   +YISGVPGTGKTA VR  V  +   ++  + P F Y+E+N M        
Sbjct: 331 DRKRGESS-AMYISGVPGTGKTATVRAVVNAM---KKNAKCPKFVYVEVNAMIFKKTVFV 386

Query: 445 RAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHNRKHHSSILVLLDEMD 504
             +N + +      +  +  R   + + A + L+  F+++           I++L+DE+D
Sbjct: 387 EIHNGIQEEF--NISKKSQTRAKISASTARQELNDIFKKQ-----DSKRPPIVILIDELD 439

Query: 505 ALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLL-PRLASRLGMNRQVFK 563
           +L        Q VLYD  +W + P S++ IIGIANTLD PER+L  R ASRL   R VF+
Sbjct: 440 SLC----NRKQDVLYDIFEWTALPQSKVTIIGIANTLDFPERMLCQRNASRLDKRRLVFQ 495

Query: 564 PYSVTQLQQILRHKL-GPQLLQHFDEDALELCTRRVAAVSGDIRRAL 609
           PY   Q+Q+I+R +L G  L++   + A+EL  +++A  +GD+R+AL
Sbjct: 496 PYRHEQIQEIVRARLQGSNLVE---KKAVELVAKKIAMNTGDLRQAL 539

gb|AAR83016.1| cell division cycle 6 [Cricetulus griseus]
(561 aa)

Score: 126 bits (317), Expect: 2.0558e-27
Length: 249, Idn/Pos/Gap = 88/130/25 (35%/52%/10%)

Query: 370 QLVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPH 429
           +L  RD E + +  FL + + G     LY+SG PGTGKTA +   +Q L++     +V  
Sbjct: 172 RLPARDKEMDVIRAFLKEHICGKKAGSLYLSGAPGTGKTACLSRILQDLKK-----EVKG 226

Query: 430 FQYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHN 489
           F+ I +N M++      +  + Q +GH           PA  +  R L++     +G   
Sbjct: 227 FKTIMLNCMSLRSAQAVFPAIAQEIGHEEMCR------PAGKDLMRKLEKHMTAEKG--- 277

Query: 490 RKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLLP 549
                 I+++LDEMD L     +  Q VLY   +W     S LV+IGIANTLDL +R+LP
Sbjct: 278 ----PMIVLVLDEMDQL----DSKGQDVLYTLFEWPWLSNSRLVLIGIANTLDLTDRILP 329

Query: 550 RLASRLGMNRQV--FKPYSVTQLQQILRHKLGP-QLLQHFDEDALELCTRRVAAVSGDIR 606
           RL +R     Q+  F PY+  Q+  IL+ +L      Q  D  A++ C R+V+AVSGDIR
Sbjct: 330 RLEARENCKPQLLNFPPYTRNQIATILQDRLNQVSREQVLDSAAIQFCARKVSAVSGDIR 389

Query: 607 RALAICLHA 615
           +AL +C  A
Sbjct: 390 KALDVCRRA 398

gb|AAH80872.1| Cdc6-prov protein [Xenopus tropicalis]
ref|NP_001007994.1| cdc6-prov protein [Xenopus tropicalis]
(554 aa)

Score: 124 bits (312), Expect: 8.14482e-27
Length: 318, Idn/Pos/Gap = 101/156/33 (31%/49%/10%)

Query: 304 NCSQESDMTPRPRAGGQLLLWPSDVGAHEHRQSRISKNAVEFAEVSEPTGSVPRLLQVSR 363
           N S  + ++P  R     LL P   G      SR ++     A + +  GS  +  + + 
Sbjct:  99 NQSATTPVSPLKRVQDPYLLSPLRRGQETPSSSRNNERKSVGARLFKQEGSCYQKAKHAL 158

Query: 364 FGAPRVQLVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQ 423
             A   +L+ RD ET  +  FLT  + G     LYISG PGTGKTA +   +Q+ +   +
Sbjct: 159 NTAIPERLLARDSETATIKAFLTSHVSGGKPGSLYISGAPGTGKTACLNKLLQESKDDLK 218

Query: 424 QGQVPHFQYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQ 483
           Q +      + IN M++      +  + + +       +GG+   A  +  R L++    
Sbjct: 219 QCKT-----VYINCMSLRSSQAVFPAIAEEI-------SGGKSSIAAKDIVRSLEKTVTS 266

Query: 484 RRGVHNRKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDL 543
           +  +        IL++LDEMD L     +  Q VLY   +W   P S +V+IGIAN LDL
Sbjct: 267 KGPI--------ILLVLDEMDQL----DSRGQDVLYTVFEWPWLPNSRVVLIGIANALDL 314

Query: 544 PERLLPRLASRLGMNRQV--FKPYSVTQLQQILRHKL----GPQLLQHFDEDALELCTRR 597
            +R+LPRL +R     Q+  F PY+  Q+  IL+ +L    G Q+L   D  A++ C R+
Sbjct: 315 TDRILPRLQARPQCKPQLLNFSPYTKDQIATILQERLNQVSGDQVL---DNAAIQFCARK 371

Query: 598 VAAVSGDIRRALAICLHA 615
           ++AVSGD R+AL IC  A
Sbjct: 372 ISAVSGDARKALDICRRA 389

emb|CAD22139.1| putative cdc6-2 protein [Arabidopsis thaliana]
emb|CAC83650.1| CDC6b protein [Arabidopsis thaliana]
ref|NP_172207.2| cell division control protein CDC6b, putative (CDC6b) [Arabidopsis thaliana]
(505 aa)

Score: 121 bits (304), Expect: 7.49499e-26
Length: 334, Idn/Pos/Gap = 97/156/32 (29%/46%/9%)

Query: 350 EPTGSVPRLLQVSRFGAPRVQLVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTA 409
           E   +V   L VS+  AP   ++CR+ E  R+ +F+  C+       LYI G PGTGK+ 
Sbjct: 108 EQMRAVKEALHVSK--APST-ILCREDEQIRIFEFVKGCIDQQKAGSLYICGCPGTGKSL 164

Query: 410 VVRCAVQQLEQRRQQGQVPHFQYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPA 469
            +   VQQ+     Q  +P    + +N  ++   T  ++ +L  +               
Sbjct: 165 SMEKVVQQVGDWSTQAGLPPVDTLSVNCTSLSKTTDIFSKILGEI--------------K 210

Query: 470 PAEAARLLDQRFRQRRGVHNRKHHSS----ILVLLDEMDALVLNHSAAAQRVLYDFLDWA 525
           P + A       +  + + ++K  SS    +L++ DEMD L+         VLYD     
Sbjct: 211 PGKNANTNSSPLQHLQNLFSQKQESSSSRMMLIIADEMDYLITKDRG----VLYDLFMLT 266

Query: 526 SRPASELVIIGIANTLDLPERLLPRLASRLGMNRQV--FKPYSVTQLQQILRHKLGPQLL 583
           + P S  ++IG+AN +DL +R LP+L S L     V  F+ YS  Q+ +IL+ +L     
Sbjct: 267 TLPFSRCILIGVANAIDLADRFLPKLKS-LNCKPMVITFRAYSKDQILRILQERLRVLSY 325

Query: 584 QHFDEDALELCTRRVAAVSGDIRRALAICLHAYARSHSEDCSLRASENE----HDRLVSA 639
             F   ALELC R+VAA SGD+R+AL +C  A      E       E++     D +V  
Sbjct: 326 VAFQPKALELCARKVAAASGDMRKALCVCRSALEILEIETRGSTGPESQGPTPDDSVVRM 385

Query: 640 VDIDEAIRELTPSSVQSAVKQLSQIEQQVLMSAA 673
             +  A+ +   S V   ++ L Q +Q ++ +AA
Sbjct: 386 DHMAAALSKTFKSPVVETIQSLPQHQQIIICAAA 419

gb|AAX26889.1| unknown [Schistosoma japonicum]
(326 aa)

Score: 121 bits (304), Expect: 8.01235e-26
Length: 238, Idn/Pos/Gap = 86/128/30 (36%/53%/12%)

Query: 424 QGQVPHFQYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRF-- 481
           + Q+P FQ I +NGM + DP + Y  + ++L    TG     +      A  LL++ F  
Sbjct:  11 ESQLPVFQTIYVNGMRVSDPKQIYIQIYEQL----TGLIATTK-----SACDLLEKEFCS  61

Query: 482 -RQRRGVHNRKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASE--LVIIGIA 538
              ++  H       +++++DE+D L        Q +LY   D  +R  +   L+++ IA
Sbjct:  62 STNKKLNHREVSEKPVILVIDELDLLCTRR----QDILYSLFDGPTRHNNRRVLIVLAIA 117

Query: 539 NTLDLPERLL-PRLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQHFDEDALELCTRR 597
           NT+DLPERLL PR+ASRLG+ R  F PYS  QL QI+RH+L   L       ALEL  R+
Sbjct: 118 NTMDLPERLLHPRVASRLGLTRLTFAPYSHEQLSQIVRHRLS-SLSNILQPKALELAARK 176

Query: 598 VAAVSGDIRRALAICLHAYARSHSEDCSLRASENEHDRLVSAVDIDEAIREL--TPSS 653
           VAAVSGD+RRAL IC  A          + +S  + ++ +    I+ A++E+  TP S
Sbjct: 177 VAAVSGDVRRALDICKRA--------AEIVSSSEKTNKEIDISHINAALKEMFVTPKS 226

pir||T46977 cell division control protein 6 [validated] - African clawed frog
gb|AAB17973.1| cell division control protein 6 [Xenopus laevis]
(554 aa)

Score: 121 bits (303), Expect: 9.46745e-26
Length: 319, Idn/Pos/Gap = 98/157/34 (30%/49%/10%)

Query: 303 NNCSQESDMTPRPRAGGQLLLWPSDVGAHEHRQSRISKNAVEFAEVSEPTGSVPRLLQVS 362
           N  +  + ++P  +     LL P   G      SR  +N+V   ++ +  GS  +  + +
Sbjct:  99 NQAAAATPLSPLKKLQDPYLLSPVRKGQETPPSSRKQRNSVG-VQLFKQEGSCYQKAKHA 157

Query: 363 RFGAPRVQLVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRR 422
              A   +L+ R+ ET  +  FLT  +       LYISG PGTGKTA +   +Q+ +   
Sbjct: 158 LNTAIPERLLARESETAFIKTFLTSHVSAGKAGSLYISGAPGTGKTACLNKLLQESKDDL 217

Query: 423 QQGQVPHFQYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFR 482
           +Q +      + IN M++      +  + + +       +GG+   A  +  R L++   
Sbjct: 218 KQCKT-----VYINCMSLRSSQAVFPAIAEEI-------SGGKSSLAAKDMVRNLEKLVT 265

Query: 483 QRRGVHNRKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLD 542
            +  +        IL++LDEMD L     +  Q VLY   +W   P S +V+IGIAN LD
Sbjct: 266 SKGPI--------ILLVLDEMDQL----DSRGQDVLYTVFEWPWLPNSRMVLIGIANALD 313

Query: 543 LPERLLPRLASRLGMNRQV--FKPYSVTQLQQILRHKL----GPQLLQHFDEDALELCTR 596
           L +R+LPRL +R     Q+  F PY+  Q+  IL+ +L    G Q+L   D  A++ C R
Sbjct: 314 LTDRILPRLQARPQCKPQLLNFSPYTKDQIATILQDRLNQVSGDQVL---DNAAIQFCAR 370

Query: 597 RVAAVSGDIRRALAICLHA 615
           +++AVSGD R+AL IC  A
Sbjct: 371 KISAVSGDARKALDICRRA 389

gb|AAH70554.1| Xcdc6 protein [Xenopus laevis]
(554 aa)

Score: 120 bits (302), Expect: 1.12805e-25
Length: 319, Idn/Pos/Gap = 98/157/34 (30%/49%/10%)

Query: 303 NNCSQESDMTPRPRAGGQLLLWPSDVGAHEHRQSRISKNAVEFAEVSEPTGSVPRLLQVS 362
           N  +  + ++P  +     LL P   G      SR  +N+V   ++ +  GS  +  + +
Sbjct:  99 NQAAAATPLSPLKKLQDPYLLSPVRKGQETPPSSRKQRNSVG-VQLFKQEGSCYQKAKHA 157

Query: 363 RFGAPRVQLVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRR 422
              A   +L+ R+ ET  +  FLT  +       LYISG PGTGKTA +   +Q+ +   
Sbjct: 158 LNTAIPERLLARESETAFIKTFLTSHVSAGKAGSLYISGAPGTGKTACLNKLLQESKDDL 217

Query: 423 QQGQVPHFQYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFR 482
           +Q +      + IN M++      +  + + +       +GG+   A  +  R L++   
Sbjct: 218 KQCKT-----VYINCMSLRSSQAVFPAIAEEI-------SGGKSSLAAKDMVRNLEKLVT 265

Query: 483 QRRGVHNRKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLD 542
            +  +        IL++LDEMD L     +  Q VLY   +W   P S +V+IGIAN LD
Sbjct: 266 SKGPI--------ILLVLDEMDQL----DSRGQDVLYTVFEWPWLPNSRMVLIGIANALD 313

Query: 543 LPERLLPRLASRLGMNRQV--FKPYSVTQLQQILRHKL----GPQLLQHFDEDALELCTR 596
           L +R+LPRL +R     Q+  F PY+  Q+  IL+ +L    G Q+L   D  A++ C R
Sbjct: 314 LTDRILPRLQARPQCKPQLLNFSPYTKDQIATILQDRLNQVSGDQVL---DNAAIQFCAR 370

Query: 597 RVAAVSGDIRRALAICLHA 615
           +++AVSGD R+AL IC  A
Sbjct: 371 KISAVSGDARKALDICRRA 389

gb|AAS52816.1| AER133Cp [Ashbya gossypii ATCC 10895]
ref|NP_984992.1| AER133Cp [Eremothecium gossypii]
(997 aa)

Score: 120 bits (301), Expect: 1.52328e-25
Length: 327, Idn/Pos/Gap = 94/157/55 (28%/48%/16%)

Query: 327 DVGAHE-HRQSRISKNAVE--FAEVSEPTGSVPRLLQVSRFGAPRVQLVCRDVETERVLK 383
           D+ A E H +S   + +VE  F++V     S     ++ +       L  R+ E   +  
Sbjct: 509 DISALENHFRSPTKQKSVETIFSKVKRQLNSTHSKEEIVKASNFEDYLPARENEFATIYL 568

Query: 384 FLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHFQYIEINGMTIPDP 443
            +   +   +   +YI+G  G GKT  VR  V++L     + ++P FQYIEING+ +   
Sbjct: 569 SMYSAIEAGTGTSIYIAGTRGVGKTLTVREVVKELLISSDRKELPQFQYIEINGLKMVKA 628

Query: 444 TRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHNRKHHSSILVLLDEM 503
           + +Y +L +++   ST  +G         A   L+  F++      R     ++VLLDE+
Sbjct: 629 SDSYEVLWKKISG-STLTSGA--------AMESLEYYFKEVPQTKKR----PVVVLLDEL 675

Query: 504 DALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLL-PRLASRLGMNRQVF 562
           DALV  +    Q V+Y+F +W +   S+ V++ +ANT+DLPER L  +++SR+G  R +F
Sbjct: 676 DALVTKN----QDVMYNFFNWTTYENSKFVVVAVANTMDLPERQLGNKVSSRIGFTRIMF 731

Query: 563 KPYSVTQLQQILRHKLGPQLLQHF----------------------------------DE 588
             Y+  +L+ I+  +L      HF                                   E
Sbjct: 732 TGYTHEELKTIINLRLMDLNDSHFYVDPETGNSYLIQDGDTTQLPKDVSKLQKVLLKISE 791

Query: 589 DALELCTRRVAAVSGDIRRALAICLHA 615
           DA+E+ +R++A+VSGD RRAL +C  A
Sbjct: 792 DAVEIASRKIASVSGDARRALKVCKRA 818

dbj|BAD91026.1| cell division control protein 6 [Eisenia fetida]
(407 aa)

Score: 120 bits (301), Expect: 1.8766e-25
Length: 281, Idn/Pos/Gap = 88/136/35 (31%/48%/12%)

Query: 374 RDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHFQYI 433
           R+ ET+ V  FLT  +      CLYISG PG+GKTAVV   V   +  +          I
Sbjct:  62 REKETDAVKSFLTKHISCKHPGCLYISGAPGSGKTAVVAKTVDSFKNNKD------CHII 115

Query: 434 EINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHNRKHH 493
            IN M++ +    Y+ +L  LG+  +                   +  R R   +     
Sbjct: 116 YINCMSVRNSVAIYDNILSLLGNSKSSMTA---------------KESRSRIEEYLTSST 160

Query: 494 SSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLLPRLAS 553
            +++++LDEMD+L     +  Q VLY   +W + P S L++IGIAN+LDL +R LPRL +
Sbjct: 161 LAVVLVLDEMDSL----DSRNQDVLYTMFEWPALPNSSLILIGIANSLDLTDRTLPRLQT 216

Query: 554 RLGMNRQV--FKPYSVTQLQQILRHKLGP-QLLQHFDEDALELCTRRVAAVSGDIRRALA 610
           R     Q+  F PYS  ++ +++  +L   +    F+  A++ C  +VAA++GD+R AL 
Sbjct: 217 RPNFRPQILNFPPYSKDEMIEVITKRLSEIEGDSIFEAKAVQFCAAKVAAMAGDVRMALD 276

Query: 611 ICLHAYARSHSEDCSLR-------ASENEHDRLVSAVDIDE 644
           IC  A     +E    R       AS N H  L+  V + +
Sbjct: 277 ICRRAVETVEAEVRHQRIAAPQGIASTNFHSTLLKRVGVQQ 317

ref|XP_340897.2| PREDICTED: similar to Cell division control protein 6 homolog (CDC6-related protein) (p62(cdc6)) [Rattus norvegicus]
(561 aa)

Score: 120 bits (300), Expect: 2.0399e-25
Length: 249, Idn/Pos/Gap = 85/129/25 (34%/51%/10%)

Query: 370 QLVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPH 429
           +L  R+ E   +  FL + + G     LY+SG PGTGKTA +   +Q  ++     +V  
Sbjct: 172 RLPAREQEMGVIRDFLKEHICGKKAGSLYLSGAPGTGKTACLSRILQDFKK-----EVKG 226

Query: 430 FQYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHN 489
           F+ I +N M++ +    +  + Q +G        G+      +  R L++     RG   
Sbjct: 227 FKTIVLNCMSLRNAQAVFPAIAQEIGREELCRPTGK------DLMRKLEKHLTAERG--- 277

Query: 490 RKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLLP 549
                 I+++LDEMD L     +  Q VLY   +W     S LV+IGIANTLDL +R+LP
Sbjct: 278 ----PMIVLVLDEMDQL----DSKGQDVLYTLFEWPWLSNSRLVLIGIANTLDLTDRILP 329

Query: 550 RLASRLGMNRQV--FKPYSVTQLQQILRHKLGP-QLLQHFDEDALELCTRRVAAVSGDIR 606
           RL +R G   ++  F PY+  Q+  IL+ +L      Q  D  A++ C R+V+AVSGDIR
Sbjct: 330 RLEAREGCKPKLLNFPPYTRNQIAAILQDRLSQVSKDQVLDSAAIQFCARKVSAVSGDIR 389

Query: 607 RALAICLHA 615
           +AL +C  A
Sbjct: 390 KALDVCRRA 398

gb|AAH56313.1| LOC402825 protein [Danio rerio]
(588 aa)

Score: 119 bits (299), Expect: 3.1744e-25
Length: 287, Idn/Pos/Gap = 93/143/38 (32%/49%/13%)

Query: 370 QLVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPH 429
           +L+ R+ E   ++ FL + +       LYISG PGTGKTA + C +Q+     Q+  +  
Sbjct: 214 RLLSREAERAAIVSFLQNHVVAEKPSSLYISGAPGTGKTACLNCVLQE-----QKALLKG 268

Query: 430 FQYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHN 489
            Q + IN M +      + +L ++L             P     ARL  +++    G   
Sbjct: 269 IQTVVINCMNLRSSHAIFPLLGEQL-----------EVPKGNSQARL--EKYLTSSG--- 312

Query: 490 RKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLLP 549
                ++L++LDEMD L     + +Q VLY   +W   P S + +IGIAN LDL +R+LP
Sbjct: 313 ----PTVLLVLDEMDQL----DSKSQEVLYTIFEWPYLPKSRVCLIGIANALDLTDRILP 364

Query: 550 RLASRLGMNRQV--FKPYSVTQLQQILRHKL----GPQLLQHFDEDALELCTRRVAAVSG 603
           RL ++     ++  F PYS  +L  I++ +L    G  +L   D  A++ C R+V+AVSG
Sbjct: 365 RLQAKPHCRPKLLNFPPYSHEELNAIVQDRLTQVSGEGVL---DAAAVQFCARKVSAVSG 421

Query: 604 DIRRALAICLHAYARSHSEDCSLRASENEHDRLVSAVDIDEAIRELT 650
           D R+AL IC  A     + D S  ASE      VS V + +  R L+
Sbjct: 422 DARKALDICRRAVEIVEAGDRSKMASEPTASSKVSRVSVPQVARVLS 468

pir||C84699 probable CDC6 protein [imported] - Arabidopsis thaliana
(535 aa)

Score: 119 bits (299), Expect: 3.1744e-25
Length: 335, Idn/Pos/Gap = 97/162/34 (28%/48%/10%)

Query: 350 EPTGSVPRLLQVSRFGAPRVQLVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTA 409
           E   +V   L VS+  AP   +VCR+ E  RV +F+  C+       LYI G PGTGK+ 
Sbjct: 111 EQMKAVKEALHVSK--APST-VVCREDEQRRVFEFVKGCMEQKKAGSLYICGCPGTGKSL 167

Query: 410 VVRCAVQQLEQRRQQGQVPHFQYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPA 469
            +     Q E+  +Q  +   + + +N  ++   T++ +I  + LG+  +G         
Sbjct: 168 SMEKVRLQAEEWAKQAGLHCPETVSVNCTSL---TKSTDIFSKILGNYESGKKANGSFSP 224

Query: 470 PAEAARLLDQRFRQRRGVHNRKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPA 529
             +  RL  Q+ +Q R          +L++ DEMD L+         VL++     + P 
Sbjct: 225 LQQLQRLFSQKQQQSRS-------KMMLIIADEMDYLITRDRG----VLHELFMLTTLPL 273

Query: 530 SELVIIGIANTLDLPERLLPRLASRLGMNRQ----VFKPYSVTQLQQILRHKLGPQLLQH 585
           S  ++IG+AN +DL +R LP+L S   +N +     F+ YS  Q+ +IL+ +L       
Sbjct: 274 SRCILIGVANAIDLADRFLPKLKS---LNCKPLVVTFRAYSKDQILRILQERLVALPFVA 330

Query: 586 FDEDALELCTRRVAAVSGDIRRALAICLHAYARSHSEDCSLRASENEHDR----LVSAVD 641
           F  +ALE+C R+V+A SGD+R+AL +C  A      E   +R S ++  +        V 
Sbjct: 331 FQSNALEICARKVSAASGDMRKALCVCRSALEILEIE---VRGSIDQEPKGPVPECQVVK 387

Query: 642 IDEAIRELT---PSSVQSAVKQLSQIEQQVLMSAA 673
           +D  I  L+    S +   ++ L Q +Q ++ SAA
Sbjct: 388 MDHMIAALSKTFKSPIVDTIQSLPQHQQIIVCSAA 422

dbj|BAD82304.1| putative cell division control protein 6 [Oryza sativa (japonica cultivar-group)]
(440 aa)

Score: 119 bits (297), Expect: 4.62089e-25
Length: 313, Idn/Pos/Gap = 93/148/29 (29%/47%/9%)

Query: 367 PRVQLVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQ 426
           P   LVCRD E  RVL+F   C+       LY+ G PGTGKT  +    + + +   +  
Sbjct:  60 PSCGLVCRDDEQSRVLEFCKGCVEQERSGSLYVCGCPGTGKTLSINKVKESVARWADETG 119

Query: 427 VPHFQYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRG 486
           +     + IN  ++      ++ +L +   R       ++        + L   F  +  
Sbjct: 120 METPDALSINCTSLAKTHEIFSKILAKFQTR-------KKATCKLSPLQQLQTMFSHKES 172

Query: 487 VHNRKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPER 546
              R     +LV++DEMD L+    A    VL+D     +   S  ++IGIAN +DL +R
Sbjct: 173 APRRM----LLVVVDEMDYLITRDRA----VLHDLFMLTTYQFSRCILIGIANAIDLADR 224

Query: 547 LLPRLASRLGMNRQ----VFKPYSVTQLQQILRHKLGPQLLQHFDEDALELCTRRVAAVS 602
            LP+L S   +N +     F+ YS  Q+  I++H+L       F+  ALE C R+VAA S
Sbjct: 225 FLPKLES---LNCKPLVVTFRAYSKDQISDIIKHRLKVLEYDVFEPLALEFCARKVAAAS 281

Query: 603 GDIRRALAICLHAYARSHSE--DCSLRASENEHDRLVSAVDIDEAIRELTPSSVQSAVKQ 660
           GD+R+AL +C     RS  E  +  L+ S ++   LV+   +D A+ +   S V  ++  
Sbjct: 282 GDMRKALGVC-----RSAVEVFEARLQESSDQEFGLVTFDHMDIALSKAFKSPVVDSILC 336

Query: 661 LSQIEQQVLMSAA 673
           L Q +Q VL + A
Sbjct: 337 LPQHQQMVLCALA 349

ref|NP_035929.1| cell division cycle 6 homolog [Mus musculus]
emb|CAA08752.1| CDC6 protein [Mus musculus]
emb|CAA11110.1| Cdc6-related protein [Mus musculus]
(589 aa)

Score: 119 bits (297), Expect: 5.55195e-25
Length: 249, Idn/Pos/Gap = 85/127/25 (34%/51%/10%)

Query: 370 QLVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPH 429
           +L  R+ E   +  FL + + G     LY+SG PGTGKTA +   +Q  ++     +V  
Sbjct: 200 RLPAREQEMGVIRNFLKEHICGKKAGSLYLSGAPGTGKTACLSRILQDFKK-----EVKG 254

Query: 430 FQYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHN 489
           F+ I +N M++      +  + Q +G            PA  +  R L++     +G   
Sbjct: 255 FKSILLNCMSLRSAQAVFPAIAQEIGREELCR------PAGKDLMRKLEKHLTAEKG--- 305

Query: 490 RKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLLP 549
                 I+++LDEMD L     +  Q VLY   +W     S LV+IGIANTLDL +R+LP
Sbjct: 306 ----PMIVLVLDEMDQL----DSKGQDVLYTLFEWPWLSNSRLVLIGIANTLDLTDRILP 357

Query: 550 RLASRLGMNRQV--FKPYSVTQLQQILRHKLGP-QLLQHFDEDALELCTRRVAAVSGDIR 606
           RL +R     Q+  F PY+  Q+  IL+ +L      Q  D  A++ C R+V+AVSGDIR
Sbjct: 358 RLEARENCKPQLLNFPPYTRNQIAAILQDRLSQVSKDQVLDSAAIQFCARKVSAVSGDIR 417

Query: 607 RALAICLHA 615
           +AL +C  A
Sbjct: 418 KALDVCRRA 426

emb|CAC59688.1| putative CDC6 [Arabidopsis thaliana]
emb|CAC81074.1| CDC6 protein [Arabidopsis thaliana]
ref|NP_850137.1| cell division control protein CDC6, putative [Arabidopsis thaliana]
(508 aa)

Score: 118 bits (296), Expect: 5.64538e-25
Length: 335, Idn/Pos/Gap = 97/162/34 (28%/48%/10%)

Query: 350 EPTGSVPRLLQVSRFGAPRVQLVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTA 409
           E   +V   L VS+  AP   +VCR+ E  RV +F+  C+       LYI G PGTGK+ 
Sbjct: 111 EQMKAVKEALHVSK--APST-VVCREDEQRRVFEFVKGCMEQKKAGSLYICGCPGTGKSL 167

Query: 410 VVRCAVQQLEQRRQQGQVPHFQYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPA 469
            +     Q E+  +Q  +   + + +N  ++   T++ +I  + LG+  +G         
Sbjct: 168 SMEKVRLQAEEWAKQAGLHCPETVSVNCTSL---TKSTDIFSKILGNYESGKKANGSFSP 224

Query: 470 PAEAARLLDQRFRQRRGVHNRKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPA 529
             +  RL  Q+ +Q R          +L++ DEMD L+         VL++     + P 
Sbjct: 225 LQQLQRLFSQKQQQSRS-------KMMLIIADEMDYLITRDRG----VLHELFMLTTLPL 273

Query: 530 SELVIIGIANTLDLPERLLPRLASRLGMNRQ----VFKPYSVTQLQQILRHKLGPQLLQH 585
           S  ++IG+AN +DL +R LP+L S   +N +     F+ YS  Q+ +IL+ +L       
Sbjct: 274 SRCILIGVANAIDLADRFLPKLKS---LNCKPLVVTFRAYSKDQILRILQERLVALPFVA 330

Query: 586 FDEDALELCTRRVAAVSGDIRRALAICLHAYARSHSEDCSLRASENEHDR----LVSAVD 641
           F  +ALE+C R+V+A SGD+R+AL +C  A      E   +R S ++  +        V 
Sbjct: 331 FQSNALEICARKVSAASGDMRKALCVCRSALEILEIE---VRGSIDQEPKGPVPECQVVK 387

Query: 642 IDEAIRELT---PSSVQSAVKQLSQIEQQVLMSAA 673
           +D  I  L+    S +   ++ L Q +Q ++ SAA
Sbjct: 388 MDHMIAALSKTFKSPIVDTIQSLPQHQQIIVCSAA 422

dbj|BAB28090.1| unnamed protein product [Mus musculus]
(562 aa)

Score: 118 bits (296), Expect: 6.08563e-25
Length: 249, Idn/Pos/Gap = 85/127/25 (34%/51%/10%)

Query: 370 QLVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPH 429
           +L  R+ E   +  FL + + G     LY+SG PGTGKTA +   +Q  ++     +V  
Sbjct: 173 RLPAREQEMGVIRNFLKEHICGKKAGSLYLSGAPGTGKTACLSRILQDFKK-----EVKG 227

Query: 430 FQYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHN 489
           F+ I +N M++      +  + Q +G            PA  +  R L++     +G   
Sbjct: 228 FKSILLNCMSLRSAQAVFPAIAQEIGREELCR------PAGKDLMRKLEKHLTAEKG--- 278

Query: 490 RKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLLP 549
                 I+++LDEMD L     +  Q VLY   +W     S LV+IGIANTLDL +R+LP
Sbjct: 279 ----PMIVLVLDEMDQL----DSKGQDVLYTLFEWPWLSNSRLVLIGIANTLDLTDRILP 330

Query: 550 RLASRLGMNRQV--FKPYSVTQLQQILRHKLGP-QLLQHFDEDALELCTRRVAAVSGDIR 606
           RL +R     Q+  F PY+  Q+  IL+ +L      Q  D  A++ C R+V+AVSGDIR
Sbjct: 331 RLEARENCKPQLLNFPPYTRNQIAAILQDRLSQVSKDQVLDSAAIQFCARKVSAVSGDIR 390

Query: 607 RALAICLHA 615
           +AL +C  A
Sbjct: 391 KALDVCRRA 399

gb|AAH52434.1| Cdc6 protein [Mus musculus]
sp|O89033|CDC6_MOUSE Cell division control protein 6 homolog (CDC6-related protein) (p62(cdc6))
dbj|BAC39341.1| unnamed protein product [Mus musculus]
(562 aa)

Score: 118 bits (296), Expect: 6.18804e-25
Length: 249, Idn/Pos/Gap = 85/127/25 (34%/51%/10%)

Query: 370 QLVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPH 429
           +L  R+ E   +  FL + + G     LY+SG PGTGKTA +   +Q  ++     +V  
Sbjct: 173 RLPAREQEMGVIRNFLKEHICGKKAGSLYLSGAPGTGKTACLSRILQDFKK-----EVKG 227

Query: 430 FQYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHN 489
           F+ I +N M++      +  + Q +G            PA  +  R L++     +G   
Sbjct: 228 FKSILLNCMSLRSAQAVFPAIAQEIGREELCR------PAGKDLMRKLEKHLTAEKG--- 278

Query: 490 RKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLLP 549
                 I+++LDEMD L     +  Q VLY   +W     S LV+IGIANTLDL +R+LP
Sbjct: 279 ----PMIVLVLDEMDQL----DSKGQDVLYTLFEWPWLSNSRLVLIGIANTLDLTDRILP 330

Query: 550 RLASRLGMNRQV--FKPYSVTQLQQILRHKLGP-QLLQHFDEDALELCTRRVAAVSGDIR 606
           RL +R     Q+  F PY+  Q+  IL+ +L      Q  D  A++ C R+V+AVSGDIR
Sbjct: 331 RLEARENCKPQLLNFPPYTRNQIAAILQDRLSQVSKDQVLDSAAIQFCARKVSAVSGDIR 390

Query: 607 RALAICLHA 615
           +AL +C  A
Sbjct: 391 KALDVCRRA 399

gb|AAC69366.1| Cdc6-related protein [Xenopus laevis]
(554 aa)

Score: 118 bits (295), Expect: 7.55998e-25
Length: 319, Idn/Pos/Gap = 97/156/34 (30%/48%/10%)

Query: 303 NNCSQESDMTPRPRAGGQLLLWPSDVGAHEHRQSRISKNAVEFAEVSEPTGSVPRLLQVS 362
           N  +  + ++P  +      L P   G      SR  +N+V   ++ +  GS  +  + +
Sbjct:  99 NQAAAATPLSPLKKLQDPYQLSPVRKGQETPPSSRKQRNSVG-VQLFKQEGSCYQKAKHA 157

Query: 363 RFGAPRVQLVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRR 422
              A   +L+ R+ ET  +  FLT  +       LYISG PGTGKTA +   +Q+ +   
Sbjct: 158 LNTAIPERLLARESETAFIKTFLTSHVSARKAGSLYISGAPGTGKTACLNKLLQESKDDL 217

Query: 423 QQGQVPHFQYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFR 482
           +Q +      + IN M++      +  + + +       +GG+   A  +  R L++   
Sbjct: 218 KQCKT-----VYINCMSLRSSQAVFPAIAEEI-------SGGKSSLAAKDMVRNLEKLVT 265

Query: 483 QRRGVHNRKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLD 542
            +  +        IL++LDEMD L     +  Q VLY   +W   P S +V+IGIAN LD
Sbjct: 266 SKGPI--------ILLVLDEMDQL----DSRGQDVLYTVFEWPWLPNSRMVLIGIANALD 313

Query: 543 LPERLLPRLASRLGMNRQV--FKPYSVTQLQQILRHKL----GPQLLQHFDEDALELCTR 596
           L +R+LPRL +R     Q+  F PY+  Q+  IL+ +L    G Q+L   D  A++ C R
Sbjct: 314 LTDRILPRLQARPQCKPQLLNFSPYTKDQIATILQDRLNQVSGDQVL---DNAAIQFCAR 370

Query: 597 RVAAVSGDIRRALAICLHA 615
           +++AVSGD R+AL IC  A
Sbjct: 371 KISAVSGDARKALDICRRA 389

gb|AAH25232.1| CDC6 homolog [Homo sapiens]
(560 aa)

Score: 117 bits (293), Expect: 1.41349e-24
Length: 249, Idn/Pos/Gap = 83/128/25 (33%/51%/10%)

Query: 370 QLVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPH 429
           +L  R+ E + +  FL + + G     LY+SG PGTGKTA +   +Q L++     ++  
Sbjct: 171 RLPAREREMDVIRNFLREHICGKKAGSLYLSGAPGTGKTACLSRILQDLKK-----ELKG 225

Query: 430 FQYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHN 489
           F+ I +N M++      +  + Q +             PA  +  R L++     +G   
Sbjct: 226 FKTIMLNCMSLRTAQAVFPAIAQEICQEEVSR------PAGKDMMRKLEKHMTAEKG--- 276

Query: 490 RKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLLP 549
                 I+++LDEMD L     +  Q VLY   +W     S LV+IGIANTLDL +R+LP
Sbjct: 277 ----PMIVLVLDEMDQL----DSKGQDVLYTLFEWPWLSNSHLVLIGIANTLDLTDRILP 328

Query: 550 RLASRLGMNRQV--FKPYSVTQLQQILRHKLGP-QLLQHFDEDALELCTRRVAAVSGDIR 606
           RL +R     Q+  F PY+  Q+  IL+ +L      Q  D  A++ C R+V+AVSGD+R
Sbjct: 329 RLQAREKCKPQLLNFPPYTRNQIVTILQDRLNQVSRDQVLDNAAVQFCARKVSAVSGDVR 388

Query: 607 RALAICLHA 615
           +AL +C  A
Sbjct: 389 KALDVCRRA 397

gb|AAN10296.1| CDC6 cell division cycle 6 homolog (S. cerevisiae) [Homo sapiens]
gb|AAB38317.1| Cdc6-related protein [Homo sapiens]
sp|Q99741|CDC6_HUMAN Cell division control protein 6 homolog (CDC6-related protein) (p62(cdc6)) (HsCDC6) (HsCDC18)
gb|AAC52071.1| HsCdc18p [Homo sapiens]
ref|NP_001245.1| CDC6 homolog [Homo sapiens]
(560 aa)

Score: 117 bits (293), Expect: 1.52373e-24
Length: 249, Idn/Pos/Gap = 83/128/25 (33%/51%/10%)

Query: 370 QLVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPH 429
           +L  R+ E + +  FL + + G     LY+SG PGTGKTA +   +Q L++     ++  
Sbjct: 171 RLPAREREMDVIRNFLREHICGKKAGSLYLSGAPGTGKTACLSRILQDLKK-----ELKG 225

Query: 430 FQYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHN 489
           F+ I +N M++      +  + Q +             PA  +  R L++     +G   
Sbjct: 226 FKTIMLNCMSLRTAQAVFPAIAQEICQEEVSR------PAGKDMMRKLEKHMTAEKG--- 276

Query: 490 RKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLLP 549
                 I+++LDEMD L     +  Q VLY   +W     S LV+IGIANTLDL +R+LP
Sbjct: 277 ----PMIVLVLDEMDQL----DSKGQDVLYTLFEWPWLSNSHLVLIGIANTLDLTDRILP 328

Query: 550 RLASRLGMNRQV--FKPYSVTQLQQILRHKLGP-QLLQHFDEDALELCTRRVAAVSGDIR 606
           RL +R     Q+  F PY+  Q+  IL+ +L      Q  D  A++ C R+V+AVSGD+R
Sbjct: 329 RLQAREKCKPQLLNFPPYTRNQIVTILQDRLNQVSRDQVLDNAAVQFCARKVSAVSGDVR 388

Query: 607 RALAICLHA 615
           +AL +C  A
Sbjct: 389 KALDVCRRA 397

dbj|BAD82303.1| putative cell division control protein 6 [Oryza sativa (japonica cultivar-group)]
(515 aa)

Score: 117 bits (292), Expect: 1.62891e-24
Length: 313, Idn/Pos/Gap = 93/148/29 (29%/47%/9%)

Query: 367 PRVQLVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQ 426
           P   LVCRD E  RVL+F   C+       LY+ G PGTGKT  +    + + +   +  
Sbjct: 135 PSCGLVCRDDEQSRVLEFCKGCVEQERSGSLYVCGCPGTGKTLSINKVKESVARWADETG 194

Query: 427 VPHFQYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRG 486
           +     + IN  ++      ++ +L +   R       ++        + L   F  +  
Sbjct: 195 METPDALSINCTSLAKTHEIFSKILAKFQTR-------KKATCKLSPLQQLQTMFSHKES 247

Query: 487 VHNRKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPER 546
              R     +LV++DEMD L+    A    VL+D     +   S  ++IGIAN +DL +R
Sbjct: 248 APRRM----LLVVVDEMDYLITRDRA----VLHDLFMLTTYQFSRCILIGIANAIDLADR 299

Query: 547 LLPRLASRLGMNRQ----VFKPYSVTQLQQILRHKLGPQLLQHFDEDALELCTRRVAAVS 602
            LP+L S   +N +     F+ YS  Q+  I++H+L       F+  ALE C R+VAA S
Sbjct: 300 FLPKLES---LNCKPLVVTFRAYSKDQISDIIKHRLKVLEYDVFEPLALEFCARKVAAAS 356

Query: 603 GDIRRALAICLHAYARSHSE--DCSLRASENEHDRLVSAVDIDEAIRELTPSSVQSAVKQ 660
           GD+R+AL +C     RS  E  +  L+ S ++   LV+   +D A+ +   S V  ++  
Sbjct: 357 GDMRKALGVC-----RSAVEVFEARLQESSDQEFGLVTFDHMDIALSKAFKSPVVDSILC 411

Query: 661 LSQIEQQVLMSAA 673
           L Q +Q VL + A
Sbjct: 412 LPQHQQMVLCALA 424

ref|XP_537648.1| PREDICTED: similar to CDC6 homolog [Canis familiaris]
(606 aa)

Score: 116 bits (290), Expect: 3.2558e-24
Length: 246, Idn/Pos/Gap = 80/126/25 (32%/51%/10%)

Query: 370 QLVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPH 429
           +L  R+ E   +  FL + + G     LY+SG PGTGKTA +   +Q LE+     ++  
Sbjct: 170 RLPAREKEMNVIRNFLREHICGKKAGSLYLSGAPGTGKTACLSRILQDLEK-----ELKD 224

Query: 430 FQYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHN 489
           F+ I +N M++ +    +  + Q +         GR      +  + L+      +G   
Sbjct: 225 FKTIMLNCMSLRNAQAVFPAIAQEICQEEVSRPAGR------DMMKKLENHMTAEKG--- 275

Query: 490 RKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLLP 549
                 I+++LDE+D L     +  Q VLY   +W     S LV+IGIANTLDL +R+LP
Sbjct: 276 ----PMIVLVLDEVDQL----DSKGQDVLYTLFEWPWLSNSRLVLIGIANTLDLTDRILP 327

Query: 550 RLASRLGMNRQV--FKPYSVTQLQQILRHKLG-PQLLQHFDEDALELCTRRVAAVSGDIR 606
           RL +R     Q+  F PY+  Q+  IL+ +L      Q  D  A++ C R+V+A+SGD+R
Sbjct: 328 RLQAREKCKPQLLNFPPYTKNQIATILQERLDLVSRAQVLDNAAIQFCARKVSALSGDVR 387

Query: 607 RALAIC 612
           +AL +C
Sbjct: 388 KALDVC 393

emb|CAA18425.1| cdc18 [Schizosaccharomyces pombe]
sp|P41411|CDC18_SCHPO Cell division control protein 18
ref|NP_595910.1| cell division control protein 18 [Schizosaccharomyces pombe]
gb|AAA02871.1| cell division cycle protein
(577 aa)

Score: 115 bits (289), Expect: 3.65923e-24
Length: 350, Idn/Pos/Gap = 98/160/63 (28%/45%/18%)

Query: 371 LVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHF 430
           +V R+ E   V  F    L  ++   LY+SG PGTGKT ++   +  +         P  
Sbjct: 169 VVGRENEKSIVESFFRQHLDANAGGALYVSGAPGTGKTVLLHNVLDHV-----VSDYPKV 223

Query: 431 QYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHNR 490
               IN MTI +P   +  +  ++                 E    L+  F Q       
Sbjct: 224 NVCYINCMTINEPKAIFEKIHSKIVKEEILENEDHHINFQCE----LESHFTQSAN---- 275

Query: 491 KHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLLPR 550
           + ++ ++++LDEMD L+    A  Q+VLY   +W SRP S L+++GIAN LD+ +R LPR
Sbjct: 276 ELYNPVIIVLDEMDHLI----AREQQVLYTLFEWPSRPTSRLILVGIANALDMTDRFLPR 331

Query: 551 LASRLGMNRQV-FKPYSVTQLQQILRHKLGPQ--------------------------LL 583
           L ++    + + F PY+  ++  I++ +L                             + 
Sbjct: 332 LRTKHITPKLLSFTPYTAQEISTIIKARLKTAATTSEKNNPFTPIKSISEVSDDSINVVS 391

Query: 584 QHFDED------ALELCTRRVAAVSGDIRRALAICLHAYARSHSEDCSLRASENEHDRLV 637
           QH DE       A+ELC R+VAA SGD+R+AL IC HA       + + R  + +HD  +
Sbjct: 392 QHADETPFIHPAAIELCARKVAASSGDLRKALDICRHAI------ELAEREWKAQHDNTL 445

Query: 638 SAVDIDEA----IRELTPSSVQSA---VKQLSQIEQQVLMSAALCGRQAV 680
           S+VDI  A    +   T +  QSA   +K L   ++ +L +  +C + ++
Sbjct: 446 SSVDIPRASIAHVVRATSAMSQSASARLKNLGLQQKAILCTLVVCEKTSL 495

gb|EAA09435.2| ENSANGP00000015641 [Anopheles gambiae str. PEST]
ref|XP_314072.2| ENSANGP00000015641 [Anopheles gambiae str. PEST]
(376 aa)

Score: 115 bits (289), Expect: 4.21688e-24
Length: 253, Idn/Pos/Gap = 80/125/28 (31%/49%/11%)

Query: 374 RDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHFQYI 433
           R+ E + ++ F+   L       LYISG PGTGKTA ++  +      ++       + +
Sbjct:   4 REKEYDELVGFVEGVLSSDGSGSLYISGPPGTGKTATLQRILNHPSFAKK------LKPV  57

Query: 434 EINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHNRKHH 493
            IN  +I      Y  + + LG +  G                 +++++     H  + H
Sbjct:  58 YINCTSIKSVGSIYKKISEELGLKVGGTT---------------EKQYQGAIEAHLERKH 102

Query: 494 SSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLLPRLAS 553
            +I+++LDE+D L    S++ Q +LY   +W +RP + L++IGIAN LDL +RLL RL +
Sbjct: 103 KTIMLVLDEIDQL----SSSKQTILYSIFEWPARPTTRLILIGIANALDLTDRLLARLQA 158

Query: 554 RLGMNRQV--FKPYSVTQLQQILRHKL-GPQLLQHFDEDALELCTRRVAAVSGDIRRALA 610
           R  +  Q+  F PY+  Q+  IL+  L     L  F E AL L   +VA+ SGDIRRAL 
Sbjct: 159 RCELKPQLIQFLPYTKQQIVAILKASLEESNSLSRFPEAALGLLAAKVASTSGDIRRALF 218

Query: 611 ICLHAYARSHSED 623
           I       +  ED
Sbjct: 219 IARRLVESAKKED 231

ref|XP_593299.1| PREDICTED: similar to CDC6 homolog, partial [Bos taurus]
(1036 aa)

Score: 115 bits (288), Expect: 5.74204e-24
Length: 249, Idn/Pos/Gap = 85/127/25 (34%/51%/10%)

Query:  370 QLVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPH  429
            QL  R+ E + +  FL + + G     LY+SG PGTGKTA +   +Q L++     ++  
Sbjct:  789 QLPAREKEMDVIRNFLREHIYGKKAGSLYLSGAPGTGKTACLSRILQDLKK-----ELKG  843

Query:  430 FQYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHN  489
            F+ I +N M++      +  + Q +             PA  +  R L+      +G   
Sbjct:  844 FKTIVLNCMSLRSAQAVFPAIAQEICQEEVSR------PAGKDMMRRLENHMTAEKG---  894

Query:  490 RKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLLP  549
                  I+++LDEMD L     +  Q VLY   +W     S LV+IGIANTLDL +R+LP
Sbjct:  895 ----PMIVLVLDEMDQL----DSRGQDVLYTLFEWPWLSNSRLVLIGIANTLDLTDRILP  946

Query:  550 RLASRLGMNRQV--FKPYSVTQLQQILRHKLG-PQLLQHFDEDALELCTRRVAAVSGDIR  606
            RL +R     Q+  F PY+  Q+  IL+ +L      Q  D  A++ C R+V+AVSGD+R
Sbjct:  947 RLQAREKCKPQLLNFPPYTKNQIATILQDRLNQASNDQVLDNAAIQFCARKVSAVSGDVR 1006

Query:  607 RALAICLHA  615
            +AL IC  A
Sbjct: 1007 KALDICRRA 1015

gb|AAO73965.1| Cdc6-related protein [Xenopus laevis]
(553 aa)

Score: 113 bits (283), Expect: 1.80097e-23
Length: 252, Idn/Pos/Gap = 85/130/33 (33%/51%/13%)

Query: 370 QLVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPH 429
           +L+ R+ ET  +  FLT  +       LYISG PGTGKTA +   +Q+ +   QQ +   
Sbjct: 164 RLLARESETAFIKTFLTSHVSDGKPGSLYISGAPGTGKTACLNKLLQESKDDLQQCKT-- 221

Query: 430 FQYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHN 489
              + IN M++      +  + + +       +GG+   A  +  R L++    +  +  
Sbjct: 222 ---VYINCMSLRSSQAVFPAIAEEI-------SGGKSSLAAKDLVRSLEKLVTSKGPI-- 269

Query: 490 RKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLLP 549
                 IL++LDEMD L     +  Q VLY   +W     S +V+IGIAN LDL +R+LP
Sbjct: 270 ------ILLVLDEMDQL----DSRGQDVLYTVFEWPWLTNSRMVLIGIANALDLTDRILP 319

Query: 550 RLASRLGMNRQV--FKPYSVTQLQQILRHKL----GPQLLQHFDEDALELCTRRVAAVSG 603
           RL +R     Q+  F PY+  Q+  IL+ +L    G Q+L   D  A++ C R+++AVSG
Sbjct: 320 RLQARPRCRPQLLNFSPYTKDQIATILQDRLNTVSGDQVL---DNAAIQFCARKISAVSG 376

Query: 604 DIRRALAICLHA 615
           D R+AL IC  A
Sbjct: 377 DARKALDICRRA 388

gb|AAH72028.1| Cdc6B protein [Xenopus laevis]
(554 aa)

Score: 113 bits (283), Expect: 2.16384e-23
Length: 252, Idn/Pos/Gap = 85/130/33 (33%/51%/13%)

Query: 370 QLVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPH 429
           +L+ R+ ET  +  FLT  +       LYISG PGTGKTA +   +Q+ +   QQ +   
Sbjct: 165 RLLARESETAFIKTFLTSHVSDGKPGSLYISGAPGTGKTACLNKLLQESKDDLQQCKT-- 222

Query: 430 FQYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHN 489
              + IN M++      +  + + +       +GG+   A  +  R L++    +  +  
Sbjct: 223 ---VYINCMSLRSSQAVFPAIAEEI-------SGGKSSLAAKDIVRSLEKLVTSKGPI-- 270

Query: 490 RKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLLP 549
                 IL++LDEMD L     +  Q VLY   +W     S +V+IGIAN LDL +R+LP
Sbjct: 271 ------ILLVLDEMDQL----DSRGQDVLYTVFEWPWLTNSRMVLIGIANALDLTDRILP 320

Query: 550 RLASRLGMNRQV--FKPYSVTQLQQILRHKL----GPQLLQHFDEDALELCTRRVAAVSG 603
           RL +R     Q+  F PY+  Q+  IL+ +L    G Q+L   D  A++ C R+++AVSG
Sbjct: 321 RLQARPRCRPQLLNFSPYTKDQIATILQDRLNTVSGDQVL---DNAAIQFCARKISAVSG 377

Query: 604 DIRRALAICLHA 615
           D R+AL IC  A
Sbjct: 378 DARKALDICRRA 389

emb|CAB41412.1| CDC6 protein [Candida albicans]
pir||T46606 cell cycle control protein cdc6 [imported] - yeast (Candida albicans)
(481 aa)

Score: 112 bits (280), Expect: 5.11047e-23
Length: 248, Idn/Pos/Gap = 71/131/26 (28%/52%/10%)

Query: 371 LVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHF 430
           L  R+ E + +  F+ + ++      LYISG PGTGKTA V+  +Q  +Q  +       
Sbjct:  95 LTSREKEAKYITDFVANSIQQKISNSLYISGPPGTGKTAQVQLILQPYQQNSR------I 148

Query: 431 QYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHNR 490
           + ++IN MT+ +P + Y+ +  ++ ++ + +   R+              F      +  
Sbjct: 149 RVVKINCMTLNNPEQIYHEIYCKIMNKLSISFHKRKTC----------DDFMTLMNDNEN 198

Query: 491 KHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWAS-----RPASELVIIGIANTLDLPE 545
           +   S++VLLDE+D+L+     + Q+VL+     AS     +   +LV+IGI+NTLDL  
Sbjct: 199 QQFDSVIVLLDELDSLI----TSDQQVLFQLFKMASINCIPQTKIKLVLIGISNTLDLNS 254

Query: 546 RLLPRLA-SRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQHFDEDALELCTRRVAAVSGD 604
           + LPRL  + + ++   F PY+  Q++ I+ ++L     + F   A++ C ++ A++SGD
Sbjct: 255 KFLPRLVRNNIQLDNLQFLPYNADQIKSIIMNRLSNLKQEIFHPGAIQFCCKKSASISGD 314

Query: 605 IRRALAIC 612
           +R+A  IC
Sbjct: 315 LRKAFDIC 322

gb|EAK97377.1| hypothetical protein CaO19.12707 [Candida albicans SC5314]
(481 aa)

Score: 112 bits (280), Expect: 5.11047e-23
Length: 248, Idn/Pos/Gap = 71/131/26 (28%/52%/10%)

Query: 371 LVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHF 430
           L  R+ E + +  F+ + ++      LYISG PGTGKTA V+  +Q  +Q  +       
Sbjct:  95 LTSREKEAKYITDFVANSIQQKISNSLYISGPPGTGKTAQVQLILQPYQQNSR------I 148

Query: 431 QYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHNR 490
           + ++IN MT+ +P + Y+ +  ++ ++ + +   R+              F      +  
Sbjct: 149 RVVKINCMTLNNPEQIYHEIYCKIMNKLSISFHKRKTC----------DDFMTLMNDNEN 198

Query: 491 KHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWAS-----RPASELVIIGIANTLDLPE 545
           +   S++VLLDE+D+L+     + Q+VL+     AS     +   +LV+IGI+NTLDL  
Sbjct: 199 QQFDSVIVLLDELDSLI----TSDQQVLFQLFKMASINCIPQTKIKLVLIGISNTLDLNS 254

Query: 546 RLLPRLA-SRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQHFDEDALELCTRRVAAVSGD 604
           + LPRL  + + ++   F PY+  Q++ I+ ++L     + F   A++ C ++ A++SGD
Sbjct: 255 KFLPRLVRNNIQLDNLQFLPYNADQIKSIIMNRLSNLKQEIFHPGAIQFCCKKSASISGD 314

Query: 605 IRRALAIC 612
           +R+A  IC
Sbjct: 315 LRKAFDIC 322

gb|EAK87413.1| ORC/CDC6 like AAA+ ATpase [Cryptosporidium parvum]
(868 aa)

Score: 110 bits (275), Expect: 1.8318e-22
Length: 301, Idn/Pos/Gap = 87/130/67 (28%/43%/22%)

Query: 367 PRVQLVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLE-----QR 421
           P+  L CR+ E E +   L   +       L+I+G+PGTGKTA V   +  LE       
Sbjct: 379 PKKVLPCREKEHEEITLVLKTSILNEGGGVLFIAGLPGTGKTATVLNTLDMLETEMNLSN 438

Query: 422 RQQGQVPHFQYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRF 481
           + Q ++       IN + +  P   Y   LQ+L   +T A      P        LD+  
Sbjct: 439 KNQSKI---SVCYINALHLSSPDHFYRTFLQKLNGANTWA------PNKEACYTSLDKYL 489

Query: 482 RQRRGVHNRKHHSSILVLLDEMDALVLN---HS---AAAQRVLYDFLDWASRPASELVII 535
           +        K     ++++DE+D L  N   HS    +   +LY  +DW  +  ++L+II
Sbjct: 490 KA-------KGSPITILVIDEIDWLQKNGTSHSTMEGSNNSLLYTLIDWPFQKNTKLIII 542

Query: 536 GIANTLDLPERLLPRLASRLGMNRQVFKPYSVTQLQQILR-------------------- 575
            IANT+DLPERL+PR  SR G  R  F P+SV  +  IL                     
Sbjct: 543 AIANTMDLPERLIPRCTSRCGYARVNFTPFSVEDMITILNDRVKYFSPGLPDINIETCDK 602

Query: 576 ----HKLGPQL--------LQHFDED--------ALELCTRRVAAVSGDIRRALAICLHA 615
                +L P++        ++   ED        A+E C RR+A  S D+RRAL +   A
Sbjct: 603 NDQGRRLSPRIRNKNKNKNIETLQEDLESVFCHKAVEFCARRIAQQSSDVRRALQVLHRA 662

Query: 616 Y 616
           +
Sbjct: 663 W 663

gb|EAA55963.1| hypothetical protein MG01614.4 [Magnaporthe grisea 70-15]
ref|XP_363688.1| hypothetical protein MG01614.4 [Magnaporthe grisea 70-15]
(598 aa)

Score: 110 bits (274), Expect: 2.09342e-22
Length: 315, Idn/Pos/Gap = 91/147/34 (28%/46%/10%)

Query: 370 QLVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPH 429
           +L+ RD E   +  FL  C   +   CLY+SG PGTGK+A+V     +L  +      P 
Sbjct: 131 RLIGRDGERASLETFLAKCTSSTPNGCLYVSGPPGTGKSAMVNAVTDELVSK-----TPS 185

Query: 430 FQYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHN 489
            +   IN M++      Y  LL++LG               +E A  L Q F     +  
Sbjct: 186 VRKAYINCMSVKSSNDLYVTLLEQLGDEIN--------ILESEPAAALQQVF-----IPK 232

Query: 490 RKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLLP 549
           RK   + LV+LDE+D ++    +     LY   +W+ + +S + ++GIAN LDL +R LP
Sbjct: 233 RKVAGAFLVVLDEIDHIL----SLDLESLYKIFEWSMQKSSRVSLVGIANALDLTDRFLP 288

Query: 550 RLASR-LGMNRQVFKPYSVTQLQQILRHKLGPQL---------LQHFDEDALELCTRRVA 599
           RL SR L      F PYS  Q++ I+  +L   +         +  F   A+ELC+R+V+
Sbjct: 289 RLKSRNLKPELLPFLPYSAPQIKAIVTDRLKSLMPAGSTNAGFIPFFHPAAIELCSRKVS 348

Query: 600 AVSGDIRRALAICLHAYARSHSEDCSLRASENEHDRLVSAVDIDEAIRELTPSSVQSAVK 659
           + +GD+R+A  I   A     +E    +  E    +++        + E TP++  S  K
Sbjct: 349 SQTGDLRKAYEILRRALDLVEAE-TKRKLEEEARQKILQMTPSKRPLGE-TPNNAASPSK 406

Query: 660 QLSQIEQQVLMSAAL 674
             S+      ++A+L
Sbjct: 407 DASRRTVPTELAASL 421

ref|NP_915553.1| putative CDC6 [Oryza sativa (japonica cultivar-group)]
(525 aa)

Score: 108 bits (270), Expect: 6.78877e-22
Length: 258, Idn/Pos/Gap = 82/123/26 (31%/47%/10%)

Query: 367 PRVQLVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQ 426
           P   LVCRD E  RVL+F   C+       LY+ G PGTGKT  +    + + +   +  
Sbjct: 151 PSCGLVCRDDEQSRVLEFCKGCVEQERSGSLYVCGCPGTGKTLSINKVKESVARWADETG 210

Query: 427 VPHFQYIEINGMTIPDPTRAYN---ILLQRLGHRSTGAAGGRRPPAPAEAARL--LDQRF 481
           +     + IN  ++      ++    L+Q L    T      R  A  + + L  L   F
Sbjct: 211 METPDALSINCTSLAKTHEIFSTDKFLMQILAKFQT------RKKATCKLSPLQQLQTMF 264

Query: 482 RQRRGVHNRKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTL 541
             +     R     +LV++DEMD L+    A    VL+D     +   S  ++IGIAN +
Sbjct: 265 SHKESAPRRM----LLVVVDEMDYLITRDRA----VLHDLFMLTTYQFSRCILIGIANAI 316

Query: 542 DLPERLLPRLASRLGMNRQ----VFKPYSVTQLQQILRHKLGPQLLQHFDEDALELCTRR 597
           DL +R LP+L S   +N +     F+ YS  Q+  I++H+L       F+  ALE C R+
Sbjct: 317 DLADRFLPKLES---LNCKPLVVTFRAYSKDQISDIIKHRLKVLEYDVFEPLALEFCARK 373

Query: 598 VAAVSGDIRRALAICLHA 615
           VAA SGD+R+AL +C  A
Sbjct: 374 VAAASGDMRKALGVCRSA 391

emb|CAF95343.1| unnamed protein product [Tetraodon nigroviridis]
(441 aa)

Score: 107 bits (266), Expect: 1.99178e-21
Length: 287, Idn/Pos/Gap = 88/131/67 (30%/45%/23%)

Query: 370 QLVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPH 429
           +L+ R+ E E +  FL + +       LYISG PGTGKTA   C +Q+++ R     +  
Sbjct:  15 RLLSREAERESIRSFLEEKVLQRRPGSLYISGAPGTGKTACFNCVLQEMKPR-----LSA  69

Query: 430 FQYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRR---PPAPAEAARLLDQRFRQRRG 486
            Q + +N M +      + +L ++L  R  G +G +R    P PA               
Sbjct:  70 VQCVMVNCMALRSSHAIFPLLAEKLKARG-GQSGLQRFLCGPGPA--------------- 113

Query: 487 VHNRKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPER 546
                    +L++LDEMD L     + AQ VLY   +W   P S L ++GIAN LDL +R
Sbjct: 114 ---------VLLVLDEMDQL----DSKAQDVLYTIFEWPYLPGSRLCLVGIANALDLTDR 160

Query: 547 LLPRLASRLGMNRQV--FKPYSVTQLQQILRHKLGP----------------------QL 582
           +LPRL +R     Q+  F PYS  +L  I++ +L                         L
Sbjct: 161 ILPRLQARPHCRPQLLHFPPYSREELVAIVQDRLAQVRRSRDRSILVVPGCFVLTALGML 220

Query: 583 LQH------FDEDALELCTRRVAAVSGDIRRALAICLHAYARSHSED 623
           +         D  A++ C R+V+AVSGD R+AL IC  A     S++
Sbjct: 221 VNQASAGGIVDASAVQFCARKVSAVSGDARKALDICRRAVEVVESDE 267

gb|EAA67848.1| hypothetical protein FG01030.1 [Gibberella zeae PH-1]
ref|XP_381206.1| hypothetical protein FG01030.1 [Gibberella zeae PH-1]
(602 aa)

Score: 104 bits (259), Expect: 1.15832e-20
Length: 260, Idn/Pos/Gap = 82/124/32 (31%/47%/12%)

Query: 365 GAPRVQLVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQ 424
           GA   QLV R+ E  ++ +FL      +   CLY+SG PGTGK+A++       E  RQ 
Sbjct: 136 GAEPGQLVGREEERNQLTEFLNRYSSPTPHGCLYVSGPPGTGKSAMIT------EMTRQY 189

Query: 425 GQVPHFQYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQR 484
                 +Y  +N M++      Y  LL        GA G     + A+A   L   F   
Sbjct: 190 ANHKDVRYAYVNCMSVKSSKDLYTTLL--------GALGQGFDASEADAITTLQALF--- 238

Query: 485 RGVHNRKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLP 544
             V   K  +  LV LDE+D ++          LY   +W+ +  S L+++GIAN LDL 
Sbjct: 239 --VPKTKSSTVHLVTLDEIDHIL----TMGLESLYRIFEWSLQKNSRLILVGIANALDLT 292

Query: 545 ERLLPRL-ASRLGMNRQVFKPYSVTQLQQILRHKLGPQL--------LQHFDEDALELCT 595
           +R LPRL A  L  +   F PY+ TQ++ I+  +L   +        +      A++LC+
Sbjct: 293 DRFLPRLKAKNLKPDLLSFLPYTATQVKNIIITRLQSLMPAGGKEGYVPFIHPAAIDLCS 352

Query: 596 RRVAAVSGDIRRALAICLHA 615
           R+V+  +GD+R+A  IC  A
Sbjct: 353 RKVSKQTGDLRKAFEICRRA 372

gb|AAC35241.2| putative CDC6 protein [Arabidopsis thaliana]
ref|NP_565686.1| cell division control protein CDC6, putative [Arabidopsis thaliana]
(539 aa)

Score: 103 bits (257), Expect: 2.07723e-20
Length: 368, Idn/Pos/Gap = 98/164/69 (26%/44%/18%)

Query: 350 EPTGSVPRLLQVSRFGAPRVQLVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTA 409
           E   +V   L VS+  AP   +VCR+ E  RV +F+  C+       LYI G PGTGK+ 
Sbjct: 111 EQMKAVKEALHVSK--APST-VVCREDEQRRVFEFVKGCMEQKKAGSLYICGCPGTGKSL 167

Query: 410 VVRCAVQQLEQRRQQGQVPHFQYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPA 469
            +     Q E+  +Q  +   + + +N  ++   T++ +I  + LG+  +G         
Sbjct: 168 SMEKVRLQAEEWAKQAGLHCPETVSVNCTSL---TKSTDIFSKILGNYESGKKANGSFSP 224

Query: 470 PAEAARLLDQRFRQRRGVHNRKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPA 529
             +  RL  Q+ +Q R          +L++ DEMD L+         VL++     + P 
Sbjct: 225 LQQLQRLFSQKQQQSRS-------KMMLIIADEMDYLITRDRG----VLHELFMLTTLPL 273

Query: 530 SELVIIG-------------------------------IANTLDLPERLLPRLASRLGMN 558
           S  ++IG                               +AN +DL +R LP+L S   +N
Sbjct: 274 SRCILIGTVFCVINVHFLKSVSYGQTSFKFKVRICPPGVANAIDLADRFLPKLKS---LN 330

Query: 559 RQ----VFKPYSVTQLQQILRHKLGPQLLQHFDEDALELCTRRVAAVSGDIRRALAICLH 614
            +     F+ YS  Q+ +IL+ +L       F  +ALE+C R+V+A SGD+R+AL +C  
Sbjct: 331 CKPLVVTFRAYSKDQILRILQERLVALPFVAFQSNALEICARKVSAASGDMRKALCVC-- 388

Query: 615 AYARSHSE--DCSLRASENEHDR----LVSAVDIDEAIRELT---PSSVQSAVKQLSQIE 665
              RS  E  +  +R S ++  +        V +D  I  L+    S +   ++ L Q +
Sbjct: 389 ---RSALEILEIEVRGSIDQEPKGPVPECQVVKMDHMIAALSKTFKSPIVDTIQSLPQHQ 445

Query: 666 QQVLMSAA 673
           Q ++ SAA
Sbjct: 446 QIIVCSAA 453

gb|AAK68875.1| cell division control protein 6 [Arabidopsis thaliana]
(539 aa)

Score: 103 bits (256), Expect: 2.47504e-20
Length: 368, Idn/Pos/Gap = 98/164/69 (26%/44%/18%)

Query: 350 EPTGSVPRLLQVSRFGAPRVQLVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTA 409
           E   +V   L VS+  AP   +VCR+ E  RV +F+  C+       LYI G PGTGK+ 
Sbjct: 111 EQMKAVKEALHVSK--APST-VVCREDEQRRVFEFVKGCMEQKKAGSLYICGCPGTGKSL 167

Query: 410 VVRCAVQQLEQRRQQGQVPHFQYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPA 469
            +     Q E+  +Q  +   + + +N  ++   T++ +I  + LG+  +G         
Sbjct: 168 SMEKVRLQAEEWAKQAGLHCPETVSVNCTSL---TKSTDIFSKILGNYESGKKANGSFSP 224

Query: 470 PAEAARLLDQRFRQRRGVHNRKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPA 529
             +  RL  Q+ +Q R          +L++ DEMD L+         VL++     + P 
Sbjct: 225 LQQLQRLFSQKQQQSRS-------KMMLIIADEMDYLITRDRG----VLHELFMLTTLPF 273

Query: 530 SELVIIG-------------------------------IANTLDLPERLLPRLASRLGMN 558
           S  ++IG                               +AN +DL +R LP+L S   +N
Sbjct: 274 SRCILIGTVFCVINVHFLKSVSYGQTSFKFKVRICPPGVANAIDLADRFLPKLKS---LN 330

Query: 559 RQ----VFKPYSVTQLQQILRHKLGPQLLQHFDEDALELCTRRVAAVSGDIRRALAICLH 614
            +     F+ YS  Q+ +IL+ +L       F  +ALE+C R+V+A SGD+R+AL +C  
Sbjct: 331 CKPLVVTFRAYSKDQILRILQERLVALPFVAFQSNALEICARKVSAASGDMRKALCVC-- 388

Query: 615 AYARSHSE--DCSLRASENEHDR----LVSAVDIDEAIRELT---PSSVQSAVKQLSQIE 665
              RS  E  +  +R S ++  +        V +D  I  L+    S +   ++ L Q +
Sbjct: 389 ---RSALEILEIEVRGSIDQEPKGPVPECQVVKMDHMIAALSKTFKSPIVDTIQSLPQHQ 445

Query: 666 QQVLMSAA 673
           Q ++ SAA
Sbjct: 446 QIIVCSAA 453

emb|CAG61211.1| unnamed protein product [Candida glabrata CBS138]
ref|XP_448250.1| unnamed protein product [Candida glabrata]
(523 aa)

Score: 102 bits (255), Expect: 3.57291e-20
Length: 299, Idn/Pos/Gap = 90/137/39 (30%/45%/13%)

Query: 371 LVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAV-----------VRCAVQQLE 419
           LV R  + ++V++FL   +       LYI+G PGTGKTA            V   V  L 
Sbjct:  95 LVSRRTQFDQVIQFLNSAISEGRSDSLYITGPPGTGKTAQLNSILKHRFTPVASPVSPLS 154

Query: 420 QRRQ-------QGQVPHFQYIEINGMTIPDPTRAYN-ILLQRLGHRSTGAAGGRRPPAPA 471
                       G V     I IN +T+ DP+  +N I L  L        G R  P   
Sbjct: 155 DITNLHDFVLPNGNVEKVAIISINCITVNDPSSIFNKIYLSFL----NSDGGNRAVPQRY 210

Query: 472 EAARLLD-QRFRQRRGVHNRKHHSSILVLLDEMDALVLNHSAA--AQRVLYDFLDWASRP 528
               +LD + F  R          + +V+LDEMD LV  +SA+  A +V+++    A  P
Sbjct: 211 SVKTMLDLKNFMTRYA-----SEMTFIVILDEMDKLVHTNSASVNATKVIFELFLLAKLP 265

Query: 529 ASELVIIGIANTLDLPERLLPR--LASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQH- 585
             +L++IGIAN+LDL +R L R  L   L     VF+PY+  Q+ +I+ H++   LL   
Sbjct: 266 EIKLLLIGIANSLDLKDRFLSRLNLKQELLPETVVFQPYTADQMYEIINHRINSVLLATE 325

Query: 586 ---FDEDALELCTRRVAAVSGDIRRALAICLHAYARSHSE--DCSLRASENEHDRLVSA 639
              F+  A+    ++ +  +GD+R+ L I  ++      E    S R   +E+DR + A
Sbjct: 326 ESLFNPMAIRFAAKKCSGNTGDLRKLLDILRNSVEVMELERITASRRCVTDENDRPLPA 384

ref|XP_329964.1| hypothetical protein [Neurospora crassa]
gb|EAA35035.1| hypothetical protein [Neurospora crassa]
(685 aa)

Score: 100 bits (250), Expect: 1.20802e-19
Length: 295, Idn/Pos/Gap = 86/132/40 (29%/44%/13%)

Query: 370 QLVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPH 429
           +L+ RD E E++  FL  C       CLY+SG PGTGK+A+V     +        +  +
Sbjct: 171 ELIGRDDEREKLNTFLDCCTTAHPSGCLYVSGPPGTGKSAIVNKVTDKFASETSTVRKAY 230

Query: 430 FQYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHN 489
                IN M+I      Y  LL +L  +             ++    L +    R     
Sbjct: 231 -----INCMSIKSSKDLYVTLLDQLVSKDEDK---EELSTESDVVAALQKLILPR----- 277

Query: 490 RKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWA-SRPASELVIIGIANTLDLPERLL 548
           +K     LV+LDE+D ++     +    LY   +W+  +  S L +IGIAN LDL +R L
Sbjct: 278 KKTQDVFLVVLDEIDHILTLDPES----LYSLFEWSLEKKNSRLALIGIANALDLTDRFL 333

Query: 549 PRLASR-LGMNRQVFKPYSVTQLQQILRHKL----------GPQLLQHFDEDALELCTRR 597
           PRL SR L        PY+  Q++ I+  +L           P  +  F   A+ELC+R+
Sbjct: 334 PRLKSRNLKPELLPILPYTAPQVKNIIITRLKSLLPGGTPKDPNYIPFFHPAAIELCSRK 393

Query: 598 VAAVSGDIRRALAICLHAYARSHSEDCSLRASENEHDRLVSAVDIDEAIRELTPS 652
           V++ +GD+RRA  IC  A     SE            RL    ++ E + +++PS
Sbjct: 394 VSSQTGDLRRAFEICRRAIDLVESE-----------TRLKHENEVKEQMLQMSPS 437

emb|CAG90448.1| unnamed protein product [Debaryomyces hansenii CBS767]
ref|XP_461978.1| unnamed protein product [Debaryomyces hansenii]
(533 aa)

Score: 98 bits (245), Expect: 4.70683e-19
Length: 280, Idn/Pos/Gap = 80/132/49 (28%/47%/17%)

Query: 365 GAPRVQLVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQ 424
           G     L  RD E E + +FL D +  ++   LYISG PGTGKTA +  ++  + +   +
Sbjct: 103 GINTTHLTTRDEEAELLNRFLVDNINNNTSDSLYISGPPGTGKTAQIEISLNHVMKEIGK 162

Query: 425 G------QVPHF--QYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARL 476
                  QV  +  + +++N M+I  P   ++ +   +  R             A+   L
Sbjct: 163 AVNVNVSQVGLYRTRLVKMNCMSISKPENVFHEIFCAMESREGQPKKSYNKKKTADDVFL 222

Query: 477 LDQRFRQRRGVHNRKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPAS-----E 531
           L         +       + ++LLDEMD L+       Q+VL+   ++AS+  S     +
Sbjct: 223 L---------LTTECDIDTTILLLDEMDYLITKD----QQVLFQLFNFASKQKSHILTNK 269

Query: 532 LVIIGIANTLDLPERLLPRLASRLGMNRQV--FKPYSVTQLQQILRHKLGPQLLQHFDED 589
           LV+IGI+N LDL ++ LPRL  R  +N Q   F PY+  Q++ I+  KL   +   +DE 
Sbjct: 270 LVLIGISNALDLTDKFLPRL-KRNCLNPQSLQFMPYTSDQIKTIIITKLKSLV---YDES 325

Query: 590 -----------------ALELCTRRVAAVSGDIRRALAIC 612
                            A++LC ++ A+V+GD+R+A  IC
Sbjct: 326 TKENQHPMSSIPIIHPAAIQLCCKKSASVTGDLRKAFDIC 365

ref|XP_523625.1| PREDICTED: similar to CDC6 homolog; CDC18 (cell division cycle 18, S.pombe, homolog)-like; CDC6-related protein; CDC6 (cell division cycle 6, S. cerevisiae) homolog [Pan troglodytes]
(967 aa)

Score: 93 bits (231), Expect: 1.92863e-17
Length: 199, Idn/Pos/Gap = 65/100/20 (32%/50%/10%)

Query: 420 QRRQQGQVPHFQYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQ 479
           +R    ++  F+ I +N M++      +  + Q +             PA  +  R L++
Sbjct: 623 EREMDKELKGFKTIMLNCMSLRTAQAVFPAIAQEICQEEVSR------PAGKDMMRKLEK 676

Query: 480 RFRQRRGVHNRKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIAN 539
                +G         I+++LDEMD L     +  Q VLY   +W     S LV+IGIAN
Sbjct: 677 HMTAEKG-------PMIVLVLDEMDQL----DSKGQDVLYTLFEWPWLSNSHLVLIGIAN 725

Query: 540 TLDLPERLLPRLASRLGMNRQV--FKPYSVTQLQQILRHKLGP-QLLQHFDEDALELCTR 596
           TLDL +R+LPRL +R     Q+  F PY+  Q+  IL+ +L      Q  D  A++ C R
Sbjct: 726 TLDLTDRILPRLQAREKCKPQLLNFPPYTRNQIVTILQDRLNQVSRDQVLDNAAIQFCAR 785

Query: 597 RVAAVSGDIRRALAICLHA 615
           +V+AVSGD+R+AL +C  A
Sbjct: 786 KVSAVSGDVRKALDVCRRA 804

pir||A86208 hypothetical protein [imported] - Arabidopsis thaliana
gb|AAF82194.1| Contains similarity to a putative CDC6 protein At2g29680 gi|3582344 from Arabidopsis thaliana BAC T27A16 gb|AC005496
(473 aa)

Score: 92 bits (229), Expect: 3.91976e-17
Length: 330, Idn/Pos/Gap = 86/141/58 (26%/42%/17%)

Query: 350 EPTGSVPRLLQVSRFGAPRVQLVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTA 409
           E   +V   L VS+  AP   ++CR+ E  R+ +F+  C+       LYI G PGTGK+ 
Sbjct: 108 EQMRAVKEALHVSK--APST-ILCREDEQIRIFEFVKGCIDQQKAGSLYICGCPGTGKSL 164

Query: 410 VVRCAVQQLEQRRQQGQVPHFQYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPA 469
            +   VQQ+     Q  +P    + +N  ++   T  ++ +L  +               
Sbjct: 165 SMEKVVQQVGDWSTQAGLPPVDTLSVNCTSLSKTTDIFSKILGEI--------------K 210

Query: 470 PAEAARLLDQRFRQRRGVHNRKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPA 529
           P + A       +  + + ++K  SS                  + R++Y          
Sbjct: 211 PGKNANTNSSPLQHLQNLFSQKQESS------------------SSRMMY---------- 242

Query: 530 SELVIIGIANTLDLPERLLPRLASRLGMNRQV--FKPYSVTQLQQILRHKLGPQLLQHFD 587
                 G+AN +DL +R LP+L S L     V  F+ YS  Q+ +IL+ +L       F 
Sbjct: 243 ------GVANAIDLADRFLPKLKS-LNCKPMVITFRAYSKDQILRILQERLRVLSYVAFQ 295

Query: 588 EDALELCTRRVAAVSGDIRRALAICLHAYARSHSEDCSLRASENE----HDRLVSAVDID 643
             ALELC R+VAA SGD+R+AL +C  A      E       E++     D +V    + 
Sbjct: 296 PKALELCARKVAAASGDMRKALCVCRSALEILEIETRGSTGPESQGPTPDDSVVRMDHMA 355

Query: 644 EAIRELTPSSVQSAVKQLSQIEQQVLMSAA 673
            A+ +   S V   ++ L Q +Q ++ +AA
Sbjct: 356 AALSKTFKSPVVETIQSLPQHQQIIICAAA 385

gb|EAK84634.1| hypothetical protein UM03496.1 [Ustilago maydis 521]
ref|XP_401111.1| hypothetical protein UM03496.1 [Ustilago maydis 521]
(793 aa)

Score: 90 bits (224), Expect: 1.45269e-16
Length: 259, Idn/Pos/Gap = 79/122/56 (30%/47%/21%)

Query: 389 LRGSSER-CLYISGVPGTGKTAVVRCAVQQLEQ----RRQQGQVPHFQYIEINGMTIPDP 443
           L G +E  CLY+ G+PGTGKTA+VR  +  L +          +P   +  +N MT+  P
Sbjct: 237 LDGDAEAACLYVCGLPGTGKTALVRSVLNSLSETVVCSSTSPSLPRVAF--VNCMTLSHP 294

Query: 444 TRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHNRKHHSSILVLLDEM 503
              +  +LQ LG   + AA G+      +A   L +   QR           IL++LDEM
Sbjct: 295 RLIFAKVLQALG---SNAAEGQSDAFAEQALSTLIRDGNQR-----------ILIVLDEM 340

Query: 504 DALVLNHSAAAQRVLYDFLDW-----------ASRPASELVIIGIANTLDLPERLLPRLA 552
           D L+   S A Q +LY    W            +R  +   +IGIAN+LDL ER +P LA
Sbjct: 341 DHLL--QSRAHQNILYKIFSWTCKSNAAAATSGARGGAACGLIGIANSLDLTERFVPLLA 398

Query: 553 SRLGMNRQV-FKPYSVTQLQQILRHKLGPQLLQHFDED---------------------A 590
           S+      + F+P+   ++  ++R +L     ++ D+D                     A
Sbjct: 399 SKGASPALLHFRPFDADEIVSVIRDRLSALYERYDDQDNETVAAERCAEHDSLALFTPTA 458

Query: 591 LELCTRRVAAVSGDIRRAL 609
           +EL  +R+AA +GD+R+AL
Sbjct: 459 VELLAKRIAAATGDLRKAL 477

ref|NP_648247.1| CG5971-PA [Drosophila melanogaster]
gb|AAF50387.1| CG5971-PA [Drosophila melanogaster]
gb|AAK93146.1| LD25083p [Drosophila melanogaster]
(662 aa)

Score: 89 bits (221), Expect: 3.15625e-16
Length: 241, Idn/Pos/Gap = 74/122/28 (30%/50%/11%)

Query: 374 RDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHFQYI 433
           R+ + + + +F ++ L   +   LY+SG PGTGKTA +   ++  +  ++       Q +
Sbjct: 270 RESQLQELREFFSNHLESQTSGSLYVSGQPGTGKTACLSLLLRDPDFSKR------LQRV 323

Query: 434 EINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHNRKHH 493
            IN  +I      Y  L   L  + +G    R      EA         QR   H +   
Sbjct: 324 YINCTSIASVGAVYKKLCTELQLKVSG----RTERDHLEAI--------QR---HLKTAK 368

Query: 494 SSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLLPRLAS 553
             +L++LDE+D L      + Q VLY   +W + P S ++++GIAN+LDL +R L RL +
Sbjct: 369 RMLLLVLDEIDQLC----TSRQEVLYTIFEWPALPGSRILLVGIANSLDLTDRALMRLNA 424

Query: 554 RLGMNRQV--FKPYSVTQLQQILRHKLG-PQLLQHFDEDALELCTRRVAAVSGDIRRALA 610
           R  +  ++  F PYS  Q+ +I + +L   ++L  F    L+L   +V+A+SGD+RRAL 
Sbjct: 425 RCELKPRLMHFPPYSKQQIVEIFKSRLAEAEVLDVFPPVTLQLLAAKVSAISGDVRRALD 484

Query: 611 I 611
           I
Sbjct: 485 I 485

gb|EAL30609.1| GA19269-PA [Drosophila pseudoobscura]
(616 aa)

Score: 88 bits (218), Expect: 7.83697e-16
Length: 241, Idn/Pos/Gap = 76/117/28 (31%/48%/11%)

Query: 374 RDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHFQYI 433
           R+ + + + ++ T  L   S   LY+SG PGTGKTA +   ++  E  ++       Q +
Sbjct: 225 REAQLQELREYFTSHLESQSSGSLYVSGQPGTGKTACLSLLLRDPEFSKR------LQRV 278

Query: 434 EINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHNRKHH 493
            IN  +I      Y  L   L  +      GR      EA         QR   H R   
Sbjct: 279 YINCTSIASVGAVYKKLCAELQLKP----AGRTERDHLEAI--------QR---HLRTAK 323

Query: 494 SSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLLPRLAS 553
             +L++LDE+D L        Q VLY   +W + P S ++++GIAN+LDL +R L RL +
Sbjct: 324 RMLLLVLDEIDQLC----TTRQAVLYTIFEWPALPGSRILLVGIANSLDLTDRTLTRLNA 379

Query: 554 RLGMNRQV--FKPYSVTQLQQILRHKLG-PQLLQHFDEDALELCTRRVAAVSGDIRRALA 610
           R  +  ++  F  Y+  Q+ +I + +L    +L  F    L+L   +V+AVSGD+RRAL 
Sbjct: 380 RCELKPRLMHFPSYTKQQIVEIFKSRLAEADVLDVFPPVTLQLLAAKVSAVSGDVRRALD 439

Query: 611 I 611
           I
Sbjct: 440 I 440

ref|NP_376166.1| hypothetical cell division control protein 6 [Sulfolobus tokodaii str. 7]
dbj|BAB65275.1| 398aa long hypothetical cell division control protein 6 [Sulfolobus tokodaii str. 7]
sp|Q975X3|CDC61_SULTO Cell division control protein 6 homolog 1 (CDC6 homolog 1)
(398 aa)

Score: 87 bits (214), Expect: 1.97867e-15
Length: 247, Idn/Pos/Gap = 73/118/32 (29%/47%/12%)

Query: 370 QLVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPH 429
           +L  R+ + +R+++ L+  +RG     ++I G+ GTGKTAV +  V++L ++        
Sbjct:  32 ELPHREEQIKRLVEILSPLMRGEKPNNIFIYGLTGTGKTAVTKFVVKKLHEKISNS----  87

Query: 430 FQYIEINGMTIPDPTRAYNILLQRLGHRS--TGAAGGRRPPAPAEAARLLDQRFRQRRGV 487
           F Y+ IN      P R    LL+ LG +   TG        + AE  R   ++  + + +
Sbjct:  88 FIYVYINTRQTDTPYRILADLLENLGSKVPFTGI-------STAELYRRFIKKVLELKPI 140

Query: 488 HNRKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPA-SELVIIGIANTLDLPER 546
                   ++++LDE+DALV  H      +LY           S++ IIGI N +   E 
Sbjct: 141 --------LVIVLDEIDALVKKH---GDDILYRLTRANYEMGKSKVSIIGITNDIKFVEF 189

Query: 547 LLPRLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQHFD----EDALELCTRRVAAVS 602
           L PR+ S L     VF PY+  +L+ IL+ +     L  +D    +D ++LC    A   
Sbjct: 190 LDPRVKSSLSEEEIVFPPYNAEELEDILKRR---ATLAFYDSVVSDDVIKLCAAIAARDH 246

Query: 603 GDIRRAL 609
           GD RRAL
Sbjct: 247 GDARRAL 253

gb|EAK97315.1| hypothetical protein CaO19.5242 [Candida albicans SC5314]
(326 aa)

Score: 82 bits (202), Expect: 4.48349e-14
Length: 128, Idn/Pos/Gap = 44/77/10 (34%/60%/7%)

Query: 491 KHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWAS-----RPASELVIIGIANTLDLPE 545
           +   S++VLLDE+D+L+     + Q+VL+     AS     +   +LV+IGI+NTLDL  
Sbjct:  44 QQFDSVIVLLDELDSLI----TSDQQVLFQLFKMASINCIPQTKIKLVLIGISNTLDLNS  99

Query: 546 RLLPRLA-SRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQHFDEDALELCTRRVAAVSGD 604
           + LPRL  + + ++   F PY+  Q++ I+ ++L     + F   A++ C ++ A++SGD
Sbjct: 100 KFLPRLVRNNIQLDNLQFLPYNADQIKSIIMNRLSNLKQEIFHPGAIQFCCKKSASISGD 159

Query: 605 IRRALAIC 612
           +R+A  IC
Sbjct: 160 LRKAFDIC 167

gb|EAL69448.1| hypothetical protein DDB0203551 [Dictyostelium discoideum]
(440 aa)

Score: 81 bits (200), Expect: 9.58004e-14
Length: 258, Idn/Pos/Gap = 63/117/32 (24%/45%/12%)

Query: 374 RDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHFQYI 433
           RD +  ++  F+    +      LYI G PGTGK+  +    + L  ++       ++ I
Sbjct:  39 RDSQYRKLKTFIDKTAKSGKGDSLYICGPPGTGKSLTLTTLSKNLSTKK-------YKPI  91

Query: 434 EINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVH----- 488
            IN M    P + Y  + ++L +  +   G        E+    D   ++  G+      
Sbjct:  92 YINCMQFNQPIKIYIEIYRKLENLVSTKKGVNESLDLIESKYFYDFDNKEEEGMEKHSDK 151

Query: 489 --NRKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPER 546
             N K    +     E+D L+   S     +LY   +W ++ +S+L++ GIAN L L ++
Sbjct: 152 NENEKKTMWVKYREYEIDILIEKFS----NILYRIFEWPTKDSSKLILFGIANDLGLVQK 207

Query: 547 LLPRLASRLGMNRQV--FKPYSVTQLQQILRHKLG-----------PQLLQHFDEDALEL 593
            LPR A ++GM  +V  FKPY+  ++ +I  H++             Q  Q F+ + LE+
Sbjct: 208 SLPRFA-KIGMEIEVLHFKPYTEEEILKIFHHRIDLVFKEYKLKEEDQKEQLFEPETLEM 266

Query: 594 CTRRVAAVSGDIRRALAI 611
            +++++    DIR+A  +
Sbjct: 267 ISKQLSVNGCDIRKAFDV 284

emb|CAD26247.1| ORIGIN RECOGNITION COMPLEX SUBUNIT 1 [Encephalitozoon cuniculi GB-M1]
ref|NP_597612.1| ORIGIN RECOGNITION COMPLEX SUBUNIT 1 [Encephalitozoon cuniculi GB-M1]
(347 aa)

Score: 81 bits (199), Expect: 1.26168e-13
Length: 284, Idn/Pos/Gap = 73/132/53 (25%/46%/18%)

Query: 374 RDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHFQYI 433
           R+ E  ++ ++L       +   +Y+SGVPG+GKT  +   ++ +E+R+    +PH   +
Sbjct:   6 REEEYLKLERYLDMFFSTGAGGIVYVSGVPGSGKTHTI---LRLMEERK----IPH---L  55

Query: 434 EINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHNRKHH 493
            +N   +      Y  +L  L          RR    +     L Q F +   +H     
Sbjct:  56 FLNATRLRSRREVYGWILTNLP-----CCSDRRCMGLSH----LRQHFIECASLH----- 101

Query: 494 SSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLL-PRLA 552
              +V++DE+D LV      +Q VLY+  D      S+L++  ++NT++LPE+L  P++ 
Sbjct: 102 ---VVVIDEVDILV----GRSQEVLYNIFDMPYLEGSKLLLFVVSNTMNLPEKLFEPKVC 154

Query: 553 SRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQHFDEDALELCTRRVAAVSGDIRRALAIC 612
           SR+G  R  F PY+  QL  ++            D   +EL ++R+ A+SGD+R+     
Sbjct: 155 SRIGGRRINFMPYTSAQLCTVVGD-------CGMDRGCVELVSKRIGAISGDVRKV---- 203

Query: 613 LHAYARSHSEDCSLRASENEHDRLVSAVDIDEAIREL-TPSSVQ 655
                    +D   R  E++ +     +D+D  +R++ TP  V 
Sbjct: 204 ---------KDVIDRVKESKGEENAGILDVDGVMRKMYTPVYVH 238

ref|NP_069082.1| cell division control protein 6, putative [Archaeoglobus fulgidus DSM 4304]
gb|AAB90989.1| cell division control protein 6, putative [Archaeoglobus fulgidus DSM 4304]
pir||D69280 cell division control protein 6 homolog - Archaeoglobus fulgidus
sp|O29995|CD61_ARCFU Cell division control protein 6 homolog 1 (CDC6 homolog 1)
(409 aa)

Score: 80 bits (196), Expect: 2.45946e-13
Length: 349, Idn/Pos/Gap = 86/147/35 (24%/42%/10%)

Query: 374 RDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHFQYI 433
           R+ +  ++   L+  LRG +   ++I G  GTGKTA V    +QLE+  ++ ++ +    
Sbjct:  32 REEQINQLALLLSPMLRGGTPSNIFIYGKTGTGKTATVLFVARQLEEASRKAKL-NVAVH  90

Query: 434 EINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHNRKHH 493
            IN   +    R    L ++ G  +    G        E  + L     +RRG       
Sbjct:  91 YINCEIVDTAYRVLASLARKFG-SNVPMTGWPTDQVYEEVKKAL-----ERRG------- 137

Query: 494 SSILVLLDEMDALVLNHSAAAQRVLYDFLDWASR-PASELVIIGIANTLDLPERLLPRLA 552
           + ++V+LDE+D LV      A+  LY      S    S + I+GI+N L   E L  R+ 
Sbjct: 138 TRVVVILDEIDKLV----KKAEEALYGLTRINSELENSSICIVGISNNLKFKEYLDARIL 193

Query: 553 SRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQHFDEDA-LELCTRRVAAVSGDIRRALAI 611
           S L     VF PY+  QL+ IL+ +          ED  ++LC    A   GD R+AL +
Sbjct: 194 SSLSEEEIVFPPYNAEQLEDILQQRAKLAFEDGVLEDGVIQLCAAIAAQEHGDARKALDL 253

Query: 612 CLHAYARSHSEDCSLRASENEHDRLVSAVDIDEAIRELTPSSVQSAVKQLSQIEQQVLMS 671
                        S   +E E D +V    + +A+R++    +   V+ L    + +L S
Sbjct: 254 L----------RVSAEIAERERDSMVRVEHVKKAVRKIETDYMIETVRTLPVHSKILLYS 303

Query: 672 AALCGRQAVQQGSETFRFQQIWHRFRQFHASTEGHPAYPLPLQDQIEEV 720
            +L     + + S  F   +++  +++        P     + D I E+
Sbjct: 304 MSL-----ISENSPKFTTGEVYCVYKKLCGKVGVDPLTQRRISDLISEL 347

emb|CAH01207.1| unnamed protein product [Kluyveromyces lactis NRRL Y-1140]
ref|XP_452356.1| unnamed protein product [Kluyveromyces lactis]
(523 aa)

Score: 79 bits (194), Expect: 4.63699e-13
Length: 351, Idn/Pos/Gap = 83/150/52 (23%/42%/14%)

Query: 358 LLQVSRFGAPRVQLVCRDVETERVLKFLTDCL--RGSSERCLYISGVPGTGKTA------ 409
           L Q S     +  L  R  E + ++ F  + +  R S++  LYI+G PGTGKTA      
Sbjct:  94 LQQSSVSNLEQTWLATRKSEYDEIMHFFHNSISDRESADNSLYITGPPGTGKTAQLDLIL 153

Query: 410 ---------------VVRCAVQQLEQRRQQGQVPHFQYI---EINGMTIPDPTRAYNILL 451
                          V +   + L     + Q   FQ I   ++N + +  P      + 
Sbjct: 154 RDKFHEIILDPKNKKVTKHDPELLNTSYFETQSDIFQSIAVAKVNCIALSKP----ECIF 209

Query: 452 QRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHNRKHHSSILVLLDEMDALVLNHS 511
           Q+L          ++     ++ + L    R +   H        + +LDEMD L+   +
Sbjct: 210 QKLLLEIVNGKYKQQHHKACDSVKNLKSFCRSKPNTH-------FIFILDEMDKLIKQTT 262

Query: 512 --AAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLLPRLASRLGMNRQV--FKPYSV 567
             ++A +++ D    A  P   + IIGIAN++DL +R+L RL  +  +  +V  F PY+ 
Sbjct: 263 VLSSATKIILDLFLLAKEPGINVTIIGIANSIDLKDRVLNRLNLQKELLPKVIHFHPYNS 322

Query: 568 TQLQQILRHKLG--PQLLQHFDEDALELCTRRVAAVSGDIRRALAICLHAYARSHSEDCS 625
            Q+ +I+R KL   P   + F   A++  T + +  +GD+RR     L    RS  +   
Sbjct: 323 EQMFEIVRSKLSIFPACFEIFQPMAIKFATTKCSGSTGDLRR-----LFDLLRSSVQLLE 377

Query: 626 LRA----SENEHDRLVSAVDIDEAIRELTPSSVQSAVKQLSQIEQQVLMSA 672
           L +    S+    R V+   + +A+ +   S+          I+Q++++ +
Sbjct: 378 LESLKGNSDKTRGRKVTITHVAKAVSKYMNSATTKTRIAPLNIQQKIILCS 428

sp|Q9YEV6|CDC6_AERPE Cell division control protein 6 homolog (CDC6 homolog)
(406 aa)

Score: 78 bits (193), Expect: 6.2096e-13
Length: 248, Idn/Pos/Gap = 77/111/37 (31%/44%/14%)

Query: 374 RDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHFQYI 433
           R+ E  R+ + L   LRG       + G+ GTGKTAV R  +++LE R     V   + I
Sbjct:  43 REAELRRLAEVLAPALRGEKPSNALLYGLTGTGKTAVARLVLRRLEARASSLGV-LVKPI 101

Query: 434 EINGMTIPDPTRAYNILLQRLGHRS--TGAAGGRRPPAPAEAARLLDQRFRQRRGVHNRK 491
            +N      P R  + + + +G R   TG + G       E    L +R  + RG++   
Sbjct: 102 YVNARHRETPYRVASAIAEAVGVRVPFTGLSVG-------EVYERLVKRLSRLRGIY--- 151

Query: 492 HHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASEL------VIIGIANTLDLPE 545
                +++LDE+D   L      Q +LY      +R   EL       ++GI N+L   E
Sbjct: 152 -----IIVLDEID--FLPKRPGGQDLLYRI----TRINQELGDRVWVSLVGITNSLGFVE 200

Query: 546 RLLPRLASRLGMNRQVFKPYSVTQLQQILRHK----LGPQLLQHFDEDALELCTRRVAAV 601
            L PR+ S LG    VF PY+  QL+ IL  +      P +L   D D + LC    A  
Sbjct: 201 NLEPRVKSSLGEVELVFPPYTAPQLRDILETRAEEAFNPGVL---DPDVVPLCAALAARE 257

Query: 602 SGDIRRAL 609
            GD RRAL
Sbjct: 258 HGDARRAL 265

emb|CAA54766.1| cell division cycle protein [Saccharomyces cerevisiae]
emb|CAA89490.1| CDC6 [Saccharomyces cerevisiae]
emb|CAA46392.1| CDC6 [Saccharomyces cerevisiae]
sp|P09119|CDC6_YEAST Cell division control protein 6
ref|NP_012341.1| Cdc6p [Saccharomyces cerevisiae]
gb|AAA34483.1| cell division cycle protein
(513 aa)

Score: 78 bits (191), Expect: 9.03916e-13
Length: 267, Idn/Pos/Gap = 70/122/41 (26%/45%/15%)

Query: 371 LVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQ--------LEQRR 422
           L  R  E E+V+ FL   +       LYI+G PGTGKTA +   ++Q        L   R
Sbjct:  78 LPARTAEYEQVMNFLAKAISEHRSDSLYITGPPGTGKTAQLDMIIRQKFQSLPLSLSTPR 137

Query: 423 QQGQV----PHFQYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLD 478
            +  +    P+ Q   ++   +PD  R  ++ +  +   S G         P+   + + 
Sbjct: 138 SKDVLRHTNPNLQ--NLSWFELPD-GRLESVAVTSINCISLGE--------PSSIFQKIF 186

Query: 479 QRFRQRRG----VHNRKH----------HSSILVLLDEMDALVLNHSAAAQ--RVLYDFL 522
             F+   G    + N +H           ++ +V+LDEMD L+  +++  Q  R + +  
Sbjct: 187 DSFQDLNGPTLQIKNMQHLQKFLEPYHKKTTFVVVLDEMDRLLHANTSETQSVRTILELF 246

Query: 523 DWASRPASELVIIGIANTLDLPERLLPRLASRLGMNRQ--VFKPYSVTQLQQILRHKLGP 580
             A  P    V+IG+AN+LD+ +R L RL    G+  Q  VF+PY+  Q+ +I+  K+  
Sbjct: 247 LLAKLPTVSFVLIGMANSLDMKDRFLSRLNLDRGLLPQTIVFQPYTAEQMYEIVIQKMSS 306

Query: 581 QLLQHFDEDALELCTRRVAAVSGDIRR 607
                F   A++   ++ A  +GD+R+
Sbjct: 307 LPTIIFQPMAIKFAAKKCAGNTGDLRK 333

gb|AAB37629.1| Cell division cycle related protein 6 [Caenorhabditis elegans]
ref|NP_491343.1| cell Division Cycle related (57.7 kD) (cdc-6) [Caenorhabditis elegans]
pir||E87754 protein C43E11.10 [imported] - Caenorhabditis elegans
(518 aa)

Score: 78 bits (191), Expect: 9.11489e-13
Length: 136, Idn/Pos/Gap = 49/78/5 (36%/57%/3%)

Query: 488 HNRKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERL 547
           H ++  + ++++LDE+D L    +AA    LY    W    + +++I+GIAN++DL ERL
Sbjct: 261 HVKQFKTPLVLVLDEIDHLANRKNAA----LYAAFQWPETLSRKIIILGIANSIDLTERL 316

Query: 548 LPRLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQHFDEDALELCTRRVAAVSGDIRR 607
           LP+L       R VF+PY+   + +IL  K+  +     D  A+EL  R+VAA+SGD+R 
Sbjct: 317 LPKLMLAKPPKRLVFEPYTKDDIVEILNDKMKNEETS-IDAKAIELTARKVAAMSGDLRT 375

Query: 608 ALAICLHAYARSHSED 623
           AL I     +R   +D
Sbjct: 376 ALHIFKQQKSRMIPDD 391

ref|NP_147262.1| DNA polymerase II [Aeropyrum pernix K1]
dbj|BAA79440.1| 377aa long hypothetical DNA polymerase II [Aeropyrum pernix K1]
pir||D72743 probable DNA polymerase II APE0475 - Aeropyrum pernix  (strain K1)
(377 aa)

Score: 78 bits (191), Expect: 1.01592e-12
Length: 248, Idn/Pos/Gap = 77/111/37 (31%/44%/14%)

Query: 374 RDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHFQYI 433
           R+ E  R+ + L   LRG       + G+ GTGKTAV R  +++LE R     V   + I
Sbjct:  14 REAELRRLAEVLAPALRGEKPSNALLYGLTGTGKTAVARLVLRRLEARASSLGV-LVKPI  72

Query: 434 EINGMTIPDPTRAYNILLQRLGHRS--TGAAGGRRPPAPAEAARLLDQRFRQRRGVHNRK 491
            +N      P R  + + + +G R   TG + G       E    L +R  + RG++   
Sbjct:  73 YVNARHRETPYRVASAIAEAVGVRVPFTGLSVG-------EVYERLVKRLSRLRGIY--- 122

Query: 492 HHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASEL------VIIGIANTLDLPE 545
                +++LDE+D   L      Q +LY      +R   EL       ++GI N+L   E
Sbjct: 123 -----IIVLDEID--FLPKRPGGQDLLYRI----TRINQELGDRVWVSLVGITNSLGFVE 171

Query: 546 RLLPRLASRLGMNRQVFKPYSVTQLQQILRHK----LGPQLLQHFDEDALELCTRRVAAV 601
            L PR+ S LG    VF PY+  QL+ IL  +      P +L   D D + LC    A  
Sbjct: 172 NLEPRVKSSLGEVELVFPPYTAPQLRDILETRAEEAFNPGVL---DPDVVPLCAALAARE 228

Query: 602 SGDIRRAL 609
            GD RRAL
Sbjct: 229 HGDARRAL 236

gb|EAA62769.1| hypothetical protein AN5676.2 [Aspergillus nidulans FGSC A4]
ref|XP_409813.1| hypothetical protein AN5676.2 [Aspergillus nidulans FGSC A4]
(612 aa)

Score: 77 bits (190), Expect: 1.32683e-12
Length: 258, Idn/Pos/Gap = 63/121/49 (24%/46%/18%)

Query: 365 GAPRVQLVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQ 424
           GA   +++ R+VE E++  F+ D ++     C+Y+SG PGTGK+A+V+  + ++E     
Sbjct: 165 GANSGRIIGREVEKEKLASFIADGMKFKKGGCMYVSGPPGTGKSALVKEVLDEVE----- 219

Query: 425 GQVPHFQYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQR 484
             +   +  ++N  ++      Y+ L + L                              
Sbjct: 220 --IKPARVAQLNCASMRTARDVYSKLTEDLCDDDD------------------------- 252

Query: 485 RGVHNRKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLP 544
             V  +     + ++LDE+D L+ + +     +L    +W+ +  S+L++IGIAN LDL 
Sbjct: 253 --VFKKSEADRLKIMLDEIDHLLTSDAG----ILQSLFEWSLQGESKLLLIGIANALDLT 306

Query: 545 ERLLPRL-ASRLGMNRQVFKPYSVTQLQQILRHKL----------GPQLLQHFDEDALEL 593
           +R LP+L A  L      F PY+ +Q+  ++  +L           P  +      A++L
Sbjct: 307 DRSLPQLKAKNLKPLLLPFLPYNASQIAGVVIERLRSLLPEGQVEDPNFIPFVQPAAIQL 366

Query: 594 CTRRVAAVSGDIRRALAI 611
           C ++VA+ +GD+R+A  +
Sbjct: 367 CAKKVASQTGDLRKAFEL 384

gb|AAA34484.1| CDC6 protein
(513 aa)

Score: 76 bits (186), Expect: 3.46366e-12
Length: 267, Idn/Pos/Gap = 69/122/41 (25%/45%/15%)

Query: 371 LVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQ--------LEQRR 422
           L  R  E E+V+ FL   +       LYI+G PGTGKTA +   ++Q        L   R
Sbjct:  78 LPARTAEYEQVMNFLAKAISEHRSDSLYITGPPGTGKTAQLDMIIRQKFQSLPLSLSTPR 137

Query: 423 QQGQV----PHFQYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLD 478
            +  +    P+ Q   ++   +PD  R  ++ +  +   S G         P+   + + 
Sbjct: 138 SKDVLRHTNPNLQ--NLSWFELPD-GRLESVAVTSINCISLGE--------PSSIFQKIF 186

Query: 479 QRFRQRRG----VHNRKH----------HSSILVLLDEMDALVLNHSAAAQ--RVLYDFL 522
             F+   G    + N +H           ++ +V+LDE+D L+  +++  Q  R + +  
Sbjct: 187 DSFQDLNGPTLQIKNIQHLQKFLEPYHKKTTFVVVLDEIDRLLHANTSETQSVRTILELF 246

Query: 523 DWASRPASELVIIGIANTLDLPERLLPRLASRLGMNRQ--VFKPYSVTQLQQILRHKLGP 580
             A  P    V+IG+AN+LD+ +R L RL    G+  Q  VF+PY+  Q+ +I+  K+  
Sbjct: 247 LLAKLPTVSFVLIGMANSLDMKDRFLSRLNFDRGLLPQTIVFQPYTAEQMYEIVIQKMSS 306

Query: 581 QLLQHFDEDALELCTRRVAAVSGDIRR 607
                F   A++   ++ A  +GD+R+
Sbjct: 307 LPTIIFQPMAIKFAAKKCAGNTGDLRK 333

emb|CAG81590.1| unnamed protein product [Yarrowia lipolytica CLIB99]
ref|XP_501295.1| hypothetical protein [Yarrowia lipolytica]
(604 aa)

Score: 74 bits (182), Expect: 1.04197e-11
Length: 213, Idn/Pos/Gap = 60/105/15 (28%/49%/7%)

Query: 370 QLVCRDVETERVLKFLTDCLRGSSER---CLYISGVPGTGKTAVVRCAVQQLEQRRQQGQ 426
           ++V R VE   +L++    L+    +    LY+SG PGTGKTA+++  + ++ + ++  +
Sbjct: 123 EMVGRQVEEATLLRYFEGRLQAKYSQPGAALYVSGPPGTGKTALLQRVMDKVFRGKEGIK 182

Query: 427 VPHFQYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRG 486
           V       IN M  P      N++ ++L       A           A+L ++ F  +  
Sbjct: 183 VA-----SINCMLAPSARAIMNLIYKQLSGVEENEALSADISFDKSVAKL-EELFMCQTS 236

Query: 487 VHNRKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPER 546
               +  +SI+VL DE+D ++       Q +L+   +WA    S L+++GIAN LDL +R
Sbjct: 237 KEFAERGTSIVVL-DEIDHIMTRD----QDILFRIFEWAFCKGSRLILVGIANALDLTDR 291

Query: 547 LLPRL-ASRLGMNRQVFKPYSVTQLQQILRHKL 578
            LPRL A+        FKPY   Q+  I++ ++
Sbjct: 292 FLPRLKANNFYPQLLKFKPYDAVQIASIIKSRI 324

ref|NP_341806.1| Cell division control 6/orc1 protein homolog  (cdc6-1) [Sulfolobus solfataricus P2]
gb|AAK40596.1| Cell division control 6/orc1 protein homolog  (cdc6-1) [Sulfolobus solfataricus P2]
sp|Q980N4|CD61_SULSO Cell division control protein 6 homolog 1 (CDC6 homolog 1)
pir||E90167 hypothetical protein cdc6-1 [imported] - Sulfolobus solfataricus
(397 aa)

Score: 74 bits (182), Expect: 1.14213e-11
Length: 245, Idn/Pos/Gap = 65/111/28 (26%/45%/11%)

Query: 370 QLVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPH 429
           +L  R+ +  ++   L    R      ++I G+ GTGKTAVV+  + +L ++     +  
Sbjct:  32 ELPHREDQIRKIASILAPLYREEKPNNIFIYGLTGTGKTAVVKFVLSKLHKKF----LGK  87

Query: 430 FQYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHN 489
           F+++ IN   I  P R    LL+ L  +            P     + +   R  + V  
Sbjct:  88 FKHVYINTRQIDTPYRVLADLLESLDVK-----------VPFTGLSIAELYRRLVKAV-- 134

Query: 490 RKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASR-PASELVIIGIANTLDLPERLL 548
           R + S ++++LDE+DA V  ++     +LY      S    S++  IGI N +   + L 
Sbjct: 135 RDYGSQVVIVLDEIDAFVKKYN---DDILYKLSRINSEVNKSKISFIGITNDVKFVDLLD 191

Query: 549 PRLASRLGMNRQVFKPYSVTQLQQILRHK----LGPQLLQHFDEDALELCTRRVAAVSGD 604
           PR+ S L     +F PY+  +L+ IL  +      P +L    ++ ++LC    A   GD
Sbjct: 192 PRVKSSLSEEEIIFPPYNAEELEDILTKRAQMAFKPGVLP---DNVIKLCAALAAREHGD 248

Query: 605 IRRAL 609
            RRAL
Sbjct: 249 ARRAL 253

ref|ZP_00148200.2| COG1474: Cdc6-related protein, AAA superfamily ATPase [Methanococcoides burtonii DSM 6242]
(411 aa)

Score: 73 bits (178), Expect: 2.81235e-11
Length: 288, Idn/Pos/Gap = 81/122/30 (28%/42%/10%)

Query: 374 RDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHFQYI 433
           R  +   +   L   LRG +   + I G  GTGKTAV R    +LE++ +   VP    +
Sbjct:  38 RTEQVNNLATILVSALRGDTPSNILIYGKTGTGKTAVARYVGIELERKSEDLDVP-CSVL  96

Query: 434 EINGMTIPDPTRAYNILLQRLGHR--STGAAGGRRPPAPAEAARLLDQRFRQ-RRGVHNR 490
            +N   I    R    L ++ G     TG                 DQ F + +  + ++
Sbjct:  97 YLNCEVIDTQYRLLANLAKQFGEDIPMTGWP--------------TDQVFSKFKEAIDSK 142

Query: 491 KHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASR-PASELVIIGIANTLDLPERLLP 549
           K    I+++LDE+D LV         VLY+     +    ++L +IGI+N L   + L P
Sbjct: 143 KQ--VIMIILDEIDKLV----KKGDDVLYNLSRINTDLKNAKLSMIGISNDLKFTDFLDP 196

Query: 550 RLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQH-FDEDALELCTRRVAAVSGDIRRA 608
           R+ S LG    +F PY   Q+  IL  +          DE  + LC+   A   GD RRA
Sbjct: 197 RVKSSLGEEEIIFPPYDAEQISDILGQRAAIAYKDDVLDEMVIPLCSAFAAQEHGDARRA 256

Query: 609 LAICLHAYARSHSEDCSLRASENEHDRLVSAVDID---EAIRELTPSS 653
           L +   A   +  ++ S  A EN   R    ++ID   E +R L   S
Sbjct: 257 LDLLRVAGELAERDNQSYVAEENVR-RAQEKIEIDRIVEVVRTLPTQS 303

emb|CAE66818.1| Hypothetical protein CBG12183 [Caenorhabditis briggsae]
(513 aa)

Score: 72 bits (177), Expect: 3.64252e-11
Length: 123, Idn/Pos/Gap = 47/73/6 (38%/59%/4%)

Query: 490 RKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLLP 549
           +K    ++++LDE+D L    + A    LY    W    + +++I+GIAN++DL ERLLP
Sbjct: 254 KKFKVPLVLVLDEIDNLANRRNEA----LYAAFQWPVTLSYKVIILGIANSIDLTERLLP 309

Query: 550 RLA-SRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQHFDEDALELCTRRVAAVSGDIRRA 608
           +L   +  + R VF+PY+   + +IL  KL  Q     D  A+EL  R+V+A+SGD+R A
Sbjct: 310 KLELGKHPLKRLVFEPYTKDDIVEILNDKL-KQEEAVVDAKAIELTARKVSAMSGDLRTA 368

Query: 609 LAI 611
           L I
Sbjct: 369 LHI 371

ref|NP_142132.1| hypothetical protein PH0124 [Pyrococcus horikoshii OT3]
dbj|BAA29193.1| 437aa long hypothetical protein [Pyrococcus horikoshii OT3]
(437 aa)

Score: 71 bits (173), Expect: 1.13297e-10
Length: 248, Idn/Pos/Gap = 66/106/35 (26%/42%/14%)

Query: 374 RDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHFQYI 433
           R  + E + + L   L+G +   +++ G  GTGKT  V+   ++L++   +  +P    I
Sbjct:  59 RHEQIETLAQILVPVLKGETPSNIFVYGKTGTGKTVTVKFVTEELKKVSHKYNIP-VDVI 117

Query: 434 EINGMTIPDPTRAYNILLQRLGHRS---TGAAGGRRPPAPAEAARLLDQRFRQRRGVHNR 490
            IN   +    R    ++    H +       G       A+  +++D R R        
Sbjct: 118 YINCEIVDTHYRVLANIVNHFKHETGIEVPLVGWPTDEVYAKLKQVIDMRER-------- 169

Query: 491 KHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASEL-----VIIGIANTLDLPE 545
                ++++LDE+D LV     +   VLY      +R  +EL      +IGI+N L   E
Sbjct: 170 ----FVIIVLDEIDKLV---KKSGDEVLYSL----TRINTELKRAKVSVIGISNDLKFKE 218

Query: 546 RLLPRLASRLGMNRQVFKPYSVTQLQQILRHK----LGPQLLQHFDEDALELCTRRVAAV 601
            L PR+ S L     VF PY   QL+ IL  +      P +L   D+  + LC    A  
Sbjct: 219 YLDPRVLSSLSEEEVVFPPYDANQLRDILMQRAEEAFYPGVL---DDGVIPLCAALAARE 275

Query: 602 SGDIRRAL 609
            GD R+AL
Sbjct: 276 HGDARKAL 283

sp|O57864|CDC6_PYRHO Cell division control protein 6 homolog (CDC6 homolog)
(419 aa)

Score: 71 bits (173), Expect: 1.23156e-10
Length: 248, Idn/Pos/Gap = 66/106/35 (26%/42%/14%)

Query: 374 RDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHFQYI 433
           R  + E + + L   L+G +   +++ G  GTGKT  V+   ++L++   +  +P    I
Sbjct:  41 RHEQIETLAQILVPVLKGETPSNIFVYGKTGTGKTVTVKFVTEELKKVSHKYNIP-VDVI  99

Query: 434 EINGMTIPDPTRAYNILLQRLGHRS---TGAAGGRRPPAPAEAARLLDQRFRQRRGVHNR 490
            IN   +    R    ++    H +       G       A+  +++D R R        
Sbjct: 100 YINCEIVDTHYRVLANIVNHFKHETGIEVPLVGWPTDEVYAKLKQVIDMRER-------- 151

Query: 491 KHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASEL-----VIIGIANTLDLPE 545
                ++++LDE+D LV     +   VLY      +R  +EL      +IGI+N L   E
Sbjct: 152 ----FVIIVLDEIDKLV---KKSGDEVLYSL----TRINTELKRAKVSVIGISNDLKFKE 200

Query: 546 RLLPRLASRLGMNRQVFKPYSVTQLQQILRHK----LGPQLLQHFDEDALELCTRRVAAV 601
            L PR+ S L     VF PY   QL+ IL  +      P +L   D+  + LC    A  
Sbjct: 201 YLDPRVLSSLSEEEVVFPPYDANQLRDILMQRAEEAFYPGVL---DDGVIPLCAALAARE 257

Query: 602 SGDIRRAL 609
            GD R+AL
Sbjct: 258 HGDARKAL 265

emb|CAB49046.1| Cdc6/orc1 cell division control protein 6 [Pyrococcus abyssi GE5]
ref|NP_125815.1| cell division control protein 6, putative [Pyrococcus abyssi GE5]
(432 aa)

Score: 70 bits (170), Expect: 2.50302e-10
Length: 251, Idn/Pos/Gap = 69/110/41 (27%/43%/16%)

Query: 374 RDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHFQYI 433
           R  + E + + L   L+G +   +++ G  GTGKT  V+   ++L++  Q+  +P  + I
Sbjct:  54 RHEQIEALAQILVPVLKGETPSNIFVYGKTGTGKTVTVKFVTEELKKVSQKYNIP-VEVI 112

Query: 434 EINGMTIPDPTRAYNILLQRLGH--RSTGA----AGGRRPPAPAEAARLLDQRFRQRRGV 487
            IN   +      Y +L   + H    TG      G       A+  +++D + R     
Sbjct: 113 YINCEIV---DTHYRVLANIVNHFKDETGIEVPLVGWPTDEVYAKLKQVIDMKER----- 164

Query: 488 HNRKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASEL-----VIIGIANTLD 542
                   ++++LDE+D LV     +   VLY      +R  +EL      +IGI+N L 
Sbjct: 165 -------FVIIVLDEIDKLV---KKSGDEVLYSL----TRINTELKRAKVSVIGISNDLK 210

Query: 543 LPERLLPRLASRLGMNRQVFKPYSVTQLQQILRHK----LGPQLLQHFDEDALELCTRRV 598
             E L PR+ S L     VF PY   QL+ IL  +      P +L+   E  + LC    
Sbjct: 211 FKEYLDPRVLSSLSEEEVVFPPYDANQLKDILTQRAEEAFYPGVLE---EGVIPLCAALA 267

Query: 599 AAVSGDIRRAL 609
           A   GD R+AL
Sbjct: 268 AREHGDARKAL 278

emb|CAA31510.1| unnamed protein product [Saccharomyces cerevisiae]
(426 aa)

Score: 69 bits (169), Expect: 3.29644e-10
Length: 256, Idn/Pos/Gap = 64/115/41 (25%/44%/16%)

Query: 382 LKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQ--------LEQRRQQGQV----PH 429
           + FL   +       LYI+G PGTGKTA +   ++Q        L   R +  +    P+
Sbjct:   1 MNFLAKAISEHRSDSLYITGPPGTGKTAQLDMIIRQKFQSLPLSLSTPRSKDVLRHTNPN  60

Query: 430 FQYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRG--- 486
            Q   ++   +PD  R  ++ +  +   S G         P+   + +   F+   G   
Sbjct:  61 LQ--NLSWFELPD-GRLESVAVTSINCISLGE--------PSSIFQKIFDSFQDLNGPTL 109

Query: 487 -VHNRKH----------HSSILVLLDEMDALVLNHSAAAQ--RVLYDFLDWASRPASELV 533
            + N +H           ++ +V+LDEMD L+  +++  Q  R + +    A  P    V
Sbjct: 110 QIKNMQHLQKFLEPYHKKTTFVVVLDEMDRLLHANTSETQSVRTILELFLLAKLPTVSFV 169

Query: 534 IIGIANTLDLPERLLPRLASRLGMNRQ--VFKPYSVTQLQQILRHKLGPQLLQHFDEDAL 591
           +IG+AN+LD+ +R   RL    G+  Q  VF+PY+  Q+ +I+  K+       F   A+
Sbjct: 170 LIGMANSLDMKDRFPSRLNLDRGLLPQTIVFQPYTAEQMYEIVIQKMSSLPTIIFQPMAI 229

Query: 592 ELCTRRVAAVSGDIRR 607
           +   ++ A  +GD+R+
Sbjct: 230 KFAAKKCAGNTGDLRK 245

sp|Q9V2F2|CDC6_PYRAB Cell division control protein 6 homolog (CDC6 homolog)
(419 aa)

Score: 69 bits (169), Expect: 3.4947e-10
Length: 251, Idn/Pos/Gap = 69/110/41 (27%/43%/16%)

Query: 374 RDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHFQYI 433
           R  + E + + L   L+G +   +++ G  GTGKT  V+   ++L++  Q+  +P  + I
Sbjct:  41 RHEQIEALAQILVPVLKGETPSNIFVYGKTGTGKTVTVKFVTEELKKVSQKYNIP-VEVI  99

Query: 434 EINGMTIPDPTRAYNILLQRLGH--RSTGA----AGGRRPPAPAEAARLLDQRFRQRRGV 487
            IN   +      Y +L   + H    TG      G       A+  +++D + R     
Sbjct: 100 YINCEIV---DTHYRVLANIVNHFKDETGIEVPLVGWPTDEVYAKLKQVIDMKER----- 151

Query: 488 HNRKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASEL-----VIIGIANTLD 542
                   ++++LDE+D LV     +   VLY      +R  +EL      +IGI+N L 
Sbjct: 152 -------FVIIVLDEIDKLV---KKSGDEVLYSL----TRINTELKRAKVSVIGISNDLK 197

Query: 543 LPERLLPRLASRLGMNRQVFKPYSVTQLQQILRHK----LGPQLLQHFDEDALELCTRRV 598
             E L PR+ S L     VF PY   QL+ IL  +      P +L+   E  + LC    
Sbjct: 198 FKEYLDPRVLSSLSEEEVVFPPYDANQLKDILTQRAEEAFYPGVLE---EGVIPLCAALA 254

Query: 599 AAVSGDIRRAL 609
           A   GD R+AL
Sbjct: 255 AREHGDARKAL 265

dbj|BAD86090.1| cell division control protein 6 homolog [Thermococcus kodakaraensis KOD1]
ref|YP_184314.1| cell division control protein 6 homolog [Thermococcus kodakaraensis KOD1]
(415 aa)

Score: 69 bits (169), Expect: 3.52398e-10
Length: 242, Idn/Pos/Gap = 68/108/15 (28%/44%/6%)

Query: 370 QLVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPH 429
           +L  R  + + +   L   LRG +   +++ G  GTGKT  V+   ++L++  Q+  +P 
Sbjct:  34 ELPHRHKQIDDLAHILVPVLRGETPSNVFVYGKTGTGKTVTVKFVTEELKKISQKYNIP-  92

Query: 430 FQYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHN 489
            + I IN   I    R    +L R+ +     +G   P          D+ + + + V +
Sbjct:  93 VEVIYINCEIIDTHYR----VLARIVNHFKEESGIEVPLVGWPT----DEVYAKLKEVID 144

Query: 490 RKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASR-PASELVIIGIANTLDLPERLL 548
            K    I+VL DE+D L+     +   +LY      S    +++ IIGI+N L   E L 
Sbjct: 145 AKERFVIIVL-DEIDKLI---KKSGDDILYSLTRINSELSKAKVSIIGISNDLKFKEYLD 200

Query: 549 PRLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQHFDEDA-LELCTRRVAAVSGDIRR 607
            R+ S L     VF PY   QL+ IL  +      +   +DA + LC    A   GD RR
Sbjct: 201 ARVLSSLSEEEVVFPPYDANQLRDILMQRAKEAFYEGVLDDAVVPLCAALAAREHGDARR 260

Query: 608 AL 609
           AL
Sbjct: 261 AL 262

ref|NP_577746.1| origin recognition protein subunit 1 [Pyrococcus furiosus DSM 3638]
gb|AAL80141.1| origin recognition protein subunit 1; (ORC1) [Pyrococcus furiosus DSM 3638]
pir||T43932 cell division control protein 6 homolog [imported] - Pyrococcus furiosus
sp|P81413|CDC6_PYRFU Cell division control protein 6 homolog (CDC6 homolog)
dbj|BAA25162.1| ORF1 [Pyrococcus furiosus]
(420 aa)

Score: 68 bits (167), Expect: 5.57615e-10
Length: 245, Idn/Pos/Gap = 66/105/29 (26%/42%/11%)

Query: 374 RDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHFQYI 433
           R  + E + + L   LRG +   +++ G  GTGKT  V+   ++L++  ++  +P    I
Sbjct:  42 RHEQIETLAQILVPVLRGETPSNIFVYGKTGTGKTVTVKFVTEELKRISEKYNIP-VDVI 100

Query: 434 EINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHNRKHH 493
            IN   +    R    ++      +     G   P        +  + +Q   +  R   
Sbjct: 101 YINCEIVDTHYRVLANIVNYFKDET-----GIEVPMVGWPTDEVYAKLKQVIDMKER--- 152

Query: 494 SSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASEL-----VIIGIANTLDLPERLL 548
             ++++LDE+D LV     +   VLY      +R  +EL      +IGI+N L   E L 
Sbjct: 153 -FVIIVLDEIDKLV---KKSGDEVLYSL----TRINTELKRAKVSVIGISNDLKFKEYLD 204

Query: 549 PRLASRLGMNRQVFKPYSVTQLQQILRHK----LGPQLLQHFDEDALELCTRRVAAVSGD 604
           PR+ S L     VF PY   QL+ IL  +      P +L   DE  + LC    A   GD
Sbjct: 205 PRVLSSLSEEEVVFPPYDANQLRDILTQRAEEAFYPGVL---DEGVIPLCAALAAREHGD 261

Query: 605 IRRAL 609
            R+AL
Sbjct: 262 ARKAL 266

emb|CAC18552.1| cell division cycle protein [Nicotiana tabacum]
(185 aa)

Score: 68 bits (167), Expect: 5.8137e-10
Length: 115, Idn/Pos/Gap = 42/62/11 (36%/53%/9%)

Query: 496 ILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLLPRLASRL 555
           +L++ DE+D L+         VL++     + P S  ++IGIAN +DL +R LP+L S  
Sbjct:  78 LLIVADELDYLITKDKV----VLHELFMLTTSPFSRFILIGIANAIDLADRFLPKLQS-- 131

Query: 556 GMNRQ----VFKPYSVTQLQQILRHKLGPQLLQHFDEDALELCTRRVAAVSGDIR 606
            MN +     F  YS  Q+  IL+ +        F   ALELC R+VA+ SGD+R
Sbjct: 132 -MNCKPAVITFCAYSKDQIISILQQRFEAFPYTVFQPQALELCARKVASASGDMR 185

gb|EAA42197.1| GLP_49_8463_9581 [Giardia lamblia ATCC 50803]
(372 aa)

Score: 64 bits (156), Expect: 1.07827e-08
Length: 264, Idn/Pos/Gap = 79/116/36 (29%/43%/13%)

Query: 369 VQLVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVR--CAVQQLEQRRQQGQ 426
           V +V RD E   +   L+      +   L++SG PGTGKT  +R  C +    Q   Q  
Sbjct:  16 VAVVGRDAELSVLADVLSLGFADGTAHGLFLSGNPGTGKTLCLRHVCRLSPSLQGALQ--  73

Query: 427 VPHFQYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRG 486
                 I IN   +  P + Y  L  R+  +S       R  AP  A + L+  F QR+ 
Sbjct:  74 ------IWINAALLARPEQVYQELHCRIFSQS-------RRMAPLRAKKALEAHF-QRQP 119

Query: 487 VHNRKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPER 546
              R    + L+++DE+D L   +       LY+ L  A  P   L+ + IAN+L  P  
Sbjct: 120 QTKR----NTLIVIDEVDHLQSKNDQIFY-FLYNTLLTAPHP---LLFVSIANSLYFP-- 169

Query: 547 LLPRLASRL-GMNRQVFKPYSVTQLQQILRHKLG------PQLLQHFDEDA-LELCTRRV 598
              R+ASRL G+ +  F  YS      I++ ++        ++ Q F  DA L+L   RV
Sbjct: 170 YTDRIASRLSGITKLEFPAYSPETFTSIIKARIQELSAEYTEVNQLFQNDAVLKLLVGRV 229

Query: 599 AAVSGDIRRALAICLHAYARSHSE 622
               GDIR AL       AR+ +E
Sbjct: 230 LHRGGDIRTALQFTFRTIARTVAE 253

ref|ZP_00296681.1| COG1474: Cdc6-related protein, AAA superfamily ATPase [Methanosarcina barkeri str. fusaro]
(414 aa)

Score: 63 bits (154), Expect: 1.74944e-08
Length: 245, Idn/Pos/Gap = 69/102/28 (28%/41%/11%)

Query: 371 LVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHF 430
           L+ R+ +   +   L   LRG +   + I G  GTGKTAV R   ++LE+  ++  +   
Sbjct:  36 LLHRNEQINSLATILVSALRGETPSNVLIYGKTGTGKTAVTRYVGKELERVSEEKSL-FC  94

Query: 431 QYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHNR 490
             + IN   I    R    LL  L             P         DQ F + +   + 
Sbjct:  95 SVVYINCEVIDTQYR----LLANLARHFEEEVPMTGWPT--------DQVFMKFKEAIDS 142

Query: 491 KHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASEL-----VIIGIANTLDLPE 545
           K    I+++LDE+D L+         VLY+     SR  ++L      +IG++N L   E
Sbjct: 143 KEQV-IVIILDEIDKLI----KKGDDVLYNL----SRINTDLQRAKVSMIGVSNDLKFTE 193

Query: 546 RLLPRLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQ-HFDEDALELCTRRVAAVSGD 604
            L PR+ S LG    +F PY   Q+  IL+ +           E  + LC    A   GD
Sbjct: 194 FLDPRVKSSLGEEELIFPPYDAEQISDILKQRAKMAYTDGSLGEMVIPLCAAFAAQEHGD 253

Query: 605 IRRAL 609
            RRAL
Sbjct: 254 ARRAL 258

gb|AAS53992.1| AFR621Cp [Ashbya gossypii ATCC 10895]
ref|NP_986168.1| AFR621Cp [Eremothecium gossypii]
(507 aa)

Score: 63 bits (154), Expect: 2.10194e-08
Length: 334, Idn/Pos/Gap = 68/147/49 (20%/44%/14%)

Query: 371 LVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQL--------EQRR 422
           L  R+ +   +  FL + +  +    LYI+G PGTGKTA +  AV+Q         E RR
Sbjct:  95 LPTREAQYREISAFLGETIGSNGGNSLYITGPPGTGKTAQLELAVRQSFHTILIGEENRR 154

Query: 423 QQ-----------------GQVPHFQYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGR 465
                              G+      + +N + +  P   ++ + ++L          +
Sbjct: 155 NAPKHDPALANTMYYELGPGKYQSVAMVSLNCIALRRPESLWSKIHEQL----------K 204

Query: 466 RPPAPAEAARLLDQRFRQRRGVHNRKHHSSILVLLDEMDALVLN--HSAAAQRVLYDFLD 523
           +     +  R +D      +       +++ +V+LDEMD L+ +    + A +++ D   
Sbjct: 205 KNAGCGDTVRSMDDL----QAFFKSYPNTAFVVILDEMDKLLTSTLEDSNATKIIVDLFL 260

Query: 524 WASRPASELVIIGIANTLDLPERLLPRLASRLGMNRQV--FKPYSVTQLQQILRHKLGP- 580
            A  P+    ++GIAN+LD+ +R L RL        +V  F PY+  ++ +I+  KL   
Sbjct: 261 LARLPSVRFTLVGIANSLDMKDRFLNRLLLSPEFLPKVINFAPYTSEEMFEIVTSKLKSV 320

Query: 581 -QLLQHFDEDALELCTRRVAAVSGDIRRALAICLHAYARSHSEDCSLRASENEHDRLVSA 639
            ++       A++   ++ ++ +GD+R+   +  ++   +  E  SL    ++    V+ 
Sbjct: 321 DKVDTIIQPMAIKFAAKKCSSNTGDLRKLFDVLRNSIELAELE--SLNRKADKTPVRVTL 378

Query: 640 VDIDEAIRE-LTPSSVQSAVKQLSQIEQQVLMSA 672
             + +     +  SS ++ + +L+ ++Q++++ A
Sbjct: 379 THVSKVFSTYMNSSSTKTRISKLN-LQQKIVLCA 411

gb|AAB85889.1| Cdc6 related protein [Methanothermobacter thermautotrophicus str. Delta H]
ref|NP_276528.1| Cdc6 related protein [Methanothermobacter thermautotrophicus str. Delta H]
pir||B69055 probable cell division control protein 6 - Methanobacterium thermoautotrophicum (strain Delta H)
sp|O27463|CD61_METTH Cell division control protein 6 homolog 1 (CDC6 homolog 1)
(382 aa)

Score: 62 bits (151), Expect: 3.67624e-08
Length: 240, Idn/Pos/Gap = 63/99/25 (26%/41%/10%)

Query: 374 RDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHFQYI 433
           R+ +   + K+  + L G +   + I G  GTGKTAV + A++QL++  +   V     I
Sbjct:  32 REEQIRSIAKYWVEALNGVTPPDITIYGKTGTGKTAVAKFAMKQLKEASKDCDVN----I  87

Query: 434 EINGMTIPDPTRAYNI---LLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHNR 490
               +   D T  Y +   L Q+L         GR  P        +   FR     +  
Sbjct:  88 RTEYIRCTDYTTEYQVIARLCQQL---------GRDVPYRGWTKAEIVNTFRNMFKKNAF 138

Query: 491 KHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLLPR 550
                ++V+LDE+D L+ N          D L +       + I+ I+N ++  + + PR
Sbjct: 139 GQDMILMVVLDEIDILLRNDG--------DGLLYTLTRTDNVSILSISNYVEFKKFIKPR 190

Query: 551 LASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQ-HFDEDALELCTRRVAAVSGDIRRAL 609
           + S L     VF PY   QL  IL  +      +   D+D + LC    A   GD R AL
Sbjct: 191 VRSSLRDREIVFPPYGAQQLVDILEERSKMSFKEGALDDDVIPLCAALAAKEEGDARYAL 250

ref|NP_633338.1| origin recognition complex subunit [Methanosarcina mazei Go1]
gb|AAM31010.1| origin recognition complex subunit [Methanosarcina mazei Goe1]
sp|Q8PXA8|CD61_METMA Cell division control protein 6 homolog 1 (CDC6 homolog 1)
(414 aa)

Score: 62 bits (151), Expect: 3.76942e-08
Length: 249, Idn/Pos/Gap = 71/106/36 (28%/42%/14%)

Query: 371 LVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHF 430
           L+ R+ +   +   L   LRG +   + I G  GTGKTAV R   ++LE R  + +    
Sbjct:  36 LLHRNDQINSLATILVSALRGETPSNVLIYGKTGTGKTAVTRYVGKELE-RVSEDKSIFC  94

Query: 431 QYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQ-RRGVHN 489
             + IN   I    R    LL  L             P         DQ F + +  + +
Sbjct:  95 SVVYINCEVIDTQYR----LLANLARHFEEEVPMTGWPT--------DQVFMKFKEAIDS 142

Query: 490 RKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASEL-----VIIGIANTLDLP 544
           R+    I+++LDE+D L+         VLY+     SR  ++L      +IG++N L   
Sbjct: 143 REQ--VIIIILDEIDKLI----KKGDDVLYNL----SRINTDLRKAKVSMIGVSNDLKFT 192

Query: 545 ERLLPRLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQHFD----EDALELCTRRVAA 600
           E L PR+ S LG    +F PY   Q+  IL+ +     + + D    E  + LC    A 
Sbjct: 193 EFLDPRVKSSLGEEELIFPPYDAEQISDILKQRAK---MAYNDGVLGEMVIPLCAAFAAQ 249

Query: 601 VSGDIRRAL 609
             GD RRAL
Sbjct: 250 EHGDARRAL 258

sp|Q9HHR1|CD65_HALN1 Cell division control protein 6 homolog 5 (CDC6 homolog 5)
(428 aa)

Score: 62 bits (150), Expect: 4.88211e-08
Length: 247, Idn/Pos/Gap = 65/111/17 (26%/44%/6%)

Query: 370 QLVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQ-LEQRRQQGQVP 428
           ++V RD + E V+ FL   L+G+    + + G  GTGK+ ++    QQ +E    +G+  
Sbjct:  27 RIVGRDEQLESVVSFLKPTLQGNRPPNMLLYGPAGTGKSLIIGAVTQQIIELCHSKGE--  84

Query: 429 HFQYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVH 488
            F  +++N   I    +A   L+Q     +  +  G  P  P E      +++R+   + 
Sbjct:  85 RFGVVQVNCQPINTLDQAVYELVQ-----TVASDVGIEPGVP-ETGVSTKRKYRRLYDLI 138

Query: 489 NRKHHSSILVLLDEMDALV---LNHSAAAQRVLYDFLDWASRP---ASELVIIGIANTLD 542
           N +H+ S++ +LDE+D LV    N   A  ++LY  L  AS       ++ +  + N   
Sbjct: 139 N-EHYDSVIFILDEIDLLVGRRANDEPAYSKLLYQ-LSRASNTNDIEGQVSVAALTNDPK 196

Query: 543 LPERLLPRLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQHFDEDALELCTRRVAAVS 602
             E +  R  S        F  Y  TQL+QIL ++          +D L L +   A   
Sbjct: 197 FMENIDGRAESSFNPRDIYFPDYDATQLRQILENRRDAFRQDALTDDVLPLVSAFAAQSH 256

Query: 603 GDIRRAL 609
           GD R+A+
Sbjct: 257 GDARKAI 263

ref|NP_281018.1| Orc7 [Halobacterium sp. NRC-1]
gb|AAG20498.1| orc / cell division control protein 6; Orc7 [Halobacterium sp. NRC-1]
pir||F84391 orc / cell division control protein 6 [imported] - Halobacterium sp. NRC-1
sp|Q9HMS3|CD63_HALN1 Cell division control protein 6 homolog 3 (CDC6 homolog 3)
(518 aa)

Score: 62 bits (150), Expect: 4.92302e-08
Length: 158, Idn/Pos/Gap = 56/74/21 (35%/46%/13%)

Query: 497 LVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASEL-----VIIGIANTLDLPERLLPRL 551
           +++LDE+D LV     +    LY+     SR  SEL      IIGI+N L   + L PR+
Sbjct: 252 VIMLDEIDKLV---EKSGDDTLYNL----SRMNSELDNSRVSIIGISNDLKFTDFLDPRV 304

Query: 552 ASRLGMNRQVFKPYSVTQLQQILRHKLGPQL-LQHFDEDALELCTRRVAAVSGDIRRALA 610
            S LG    VF PY   QL+ IL+H+           +D L LC    A   GD RRAL 
Sbjct: 305 KSSLGEEEIVFPPYDANQLRDILQHRSDVAFKADALSDDVLPLCAAFAAQEHGDARRALD 364

Query: 611 ICLHA-------YARSHSEDCSLRASEN-EHDRLVSAV 640
           +   A        A + +ED   RA +  E DR+V  V
Sbjct: 365 LLRTAGELAERDQAENVTEDHVRRAQDKIELDRVVEVV 402

ref|NP_395780.1| Orc5 [Halobacterium sp. NRC-1]
gb|AAG20915.1| orc / cell division control protein 6; Orc5 [Halobacterium sp. NRC-1]
(481 aa)

Score: 61 bits (148), Expect: 8.25843e-08
Length: 247, Idn/Pos/Gap = 65/111/17 (26%/44%/6%)

Query: 370 QLVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQ-LEQRRQQGQVP 428
           ++V RD + E V+ FL   L+G+    + + G  GTGK+ ++    QQ +E    +G+  
Sbjct:  80 RIVGRDEQLESVVSFLKPTLQGNRPPNMLLYGPAGTGKSLIIGAVTQQIIELCHSKGE-- 137

Query: 429 HFQYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVH 488
            F  +++N   I    +A   L+Q     +  +  G  P  P E      +++R+   + 
Sbjct: 138 RFGVVQVNCQPINTLDQAVYELVQ-----TVASDVGIEPGVP-ETGVSTKRKYRRLYDLI 191

Query: 489 NRKHHSSILVLLDEMDALV---LNHSAAAQRVLYDFLDWASRP---ASELVIIGIANTLD 542
           N +H+ S++ +LDE+D LV    N   A  ++LY  L  AS       ++ +  + N   
Sbjct: 192 N-EHYDSVIFILDEIDLLVGRRANDEPAYSKLLYQ-LSRASNTNDIEGQVSVAALTNDPK 249

Query: 543 LPERLLPRLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQHFDEDALELCTRRVAAVS 602
             E +  R  S        F  Y  TQL+QIL ++          +D L L +   A   
Sbjct: 250 FMENIDGRAESSFNPRDIYFPDYDATQLRQILENRRDAFRQDALTDDVLPLVSAFAAQSH 309

Query: 603 GDIRRAL 609
           GD R+A+
Sbjct: 310 GDARKAI 316

sp|Q8TUR2|CD61_METAC Cell division control protein 6 homolog 1 (CDC6 homolog 1)
(414 aa)

Score: 61 bits (148), Expect: 8.82849e-08
Length: 248, Idn/Pos/Gap = 70/104/34 (28%/41%/13%)

Query: 371 LVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHF 430
           L+ R+ +   +   L   LRG +   + I G  GTGKTAV R   ++LE R  + +    
Sbjct:  36 LLHRNEQINSLATILVSALRGETPSNVLIYGKTGTGKTAVTRYVGKELE-RVSEDKSLFC  94

Query: 431 QYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHNR 490
             + IN   I    R    LL  L             P         DQ F + +   + 
Sbjct:  95 SVVYINCEVIDTQYR----LLANLARHFEEEVPMTGWPT--------DQVFMKFKEAIDA 142

Query: 491 KHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASEL-----VIIGIANTLDLPE 545
           +    I+++LDE+D L+         VLY+     SR  ++L      +IG++N L   E
Sbjct: 143 RDQV-IIIILDEIDKLI----KKGDDVLYNL----SRINTDLRKAKVSMIGVSNDLKFTE 193

Query: 546 RLLPRLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQHFD----EDALELCTRRVAAV 601
            L PR+ S LG    +F PY   Q+  IL+ +     + + D    E  + LC    A  
Sbjct: 194 FLDPRVKSSLGEEELIFPPYDAEQISDILKQRAK---MAYNDGVLGEMVIPLCAAFAAQE 250

Query: 602 SGDIRRAL 609
            GD RRAL
Sbjct: 251 HGDARRAL 258

ref|NP_614975.1| cell division control protein 6 [Methanosarcina acetivorans C2A]
gb|AAM03455.1| cell division control protein 6 [Methanosarcina acetivorans str. C2A]
(420 aa)

Score: 61 bits (148), Expect: 9.75821e-08
Length: 248, Idn/Pos/Gap = 70/104/34 (28%/41%/13%)

Query: 371 LVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHF 430
           L+ R+ +   +   L   LRG +   + I G  GTGKTAV R   ++LE R  + +    
Sbjct:  42 LLHRNEQINSLATILVSALRGETPSNVLIYGKTGTGKTAVTRYVGKELE-RVSEDKSLFC 100

Query: 431 QYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHNR 490
             + IN   I    R    LL  L             P         DQ F + +   + 
Sbjct: 101 SVVYINCEVIDTQYR----LLANLARHFEEEVPMTGWPT--------DQVFMKFKEAIDA 148

Query: 491 KHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASEL-----VIIGIANTLDLPE 545
           +    I+++LDE+D L+         VLY+     SR  ++L      +IG++N L   E
Sbjct: 149 RDQV-IIIILDEIDKLI----KKGDDVLYNL----SRINTDLRKAKVSMIGVSNDLKFTE 199

Query: 546 RLLPRLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQHFD----EDALELCTRRVAAV 601
            L PR+ S LG    +F PY   Q+  IL+ +     + + D    E  + LC    A  
Sbjct: 200 FLDPRVKSSLGEEELIFPPYDAEQISDILKQRAK---MAYNDGVLGEMVIPLCAAFAAQE 256

Query: 602 SGDIRRAL 609
            GD RRAL
Sbjct: 257 HGDARRAL 264

gb|AAV47479.1| cell division control protein 6-like [Haloarcula marismortui ATCC 43049]
ref|YP_137185.1| cell division control protein 6-like [Haloarcula marismortui ATCC 43049]
sp|Q5UZ24|CDC64_HALMA Cell division control protein 6 homolog 4 (CDC6 homolog 4)
(524 aa)

Score: 58 bits (140), Expect: 8.39983e-07
Length: 124, Idn/Pos/Gap = 44/59/13 (35%/47%/10%)

Query: 492 HHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASEL-----VIIGIANTLDLPER 546
           H   ++++LDE+D LV     +    LY+     SR  SEL      I+GI+N L   + 
Sbjct: 254 HERVVVIMLDEIDKLV---EKSGDDTLYNL----SRMNSELENSRVSIMGISNDLKFTDF 306

Query: 547 LLPRLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLL-QHFDEDALELCTRRVAAVSGDI 605
           L PR+ S LG    VF PY   QL+ IL+ +           ED + LC    A   GD 
Sbjct: 307 LDPRVKSSLGEEEIVFPPYDANQLRDILQARSDVAFKGDALTEDVIPLCAAFAAQEHGDA 366

Query: 606 RRAL 609
           RRAL
Sbjct: 367 RRAL 370

gb|EAL37159.1| hypothetical protein Chro.70263 [Cryptosporidium hominis]
(550 aa)

Score: 56 bits (135), Expect: 3.06151e-06
Length: 390, Idn/Pos/Gap = 85/163/52 (21%/41%/13%)

Query: 370 QLVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQ-GQV- 427
           + + R  E + + +++  C+  S    +YISG PGTGKT  +   +  LE    + G V 
Sbjct:  52 EFLGRANEFKEISEYIRSCILCSISGIIYISGSPGTGKTCTINRILNILESDSSKLGFVK 111

Query: 428 -PHFQYIEINGMTI----------PDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARL 476
              ++ I  N   +          P+    +  LL  +  ++      +R  + +E  + 
Sbjct: 112 PSSYKIIRTNASKVVSYFNKNSGLPNGISLFVHLLDLMKFQTRIIEEFKRI-SRSEGFQE 170

Query: 477 LDQRFRQRRGVHNRKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIG 536
               F ++  + N++  +  +V +DE+D L  ++      V   F    + P S  V+I 
Sbjct: 171 CIMYFMKQ--ISNKR--AKFIVFIDEID-LARSNRNHGDAVFELFKAIINFPNSGFVLIV 225

Query: 537 IANTLDLPERLLPRLASRLG----MNRQVFKPYSVTQLQQILRHKLGPQLLQHFDEDAL- 591
            +NT+ +   ++ ++   L     +   VF PYS   L+ I+  ++  +   +F  D+L 
Sbjct: 226 ASNTVQIGNEIVKKIGVNLKNKGRIKLMVFSPYSHNTLRDIVLQRI--ERASNFKNDSLL 283

Query: 592 -----ELCTRRVAAVSGDIRRALAICLHAYAR------SHSEDCSLRASENEHDRLVSAV 640
                ELC R+VA++ GD RR L  C     +      S  +   + + E+E    +   
Sbjct: 284 NKAGIELCVRKVASIYGDCRRTLDACYLTLGKFVFERQSQIQKEKIASDESEDGNSIQME 343

Query: 641 DIDE-AIRELTPSSVQSAVKQLSQIEQQVLMSAALCGRQAVQQGSETFRFQQIWHRFRQF 699
           D+   + RE +P   +S +          L + ++    +V   S    FQ +  R    
Sbjct: 344 DLSNVSTRESSPKYNRSPLDSQEVNNLHRLRTRSMPANMSVPIAS----FQNVIGR---I 396

Query: 700 HASTEG--HPAYPLPLQDQIEEVWHILMGL 727
           H + +G  +    LPL  Q     +++MG+
Sbjct: 397 HQTNQGRLNLIKTLPLHQQ-----YVIMGI 421

gb|EAK90256.1| ORC/CDC6 like AAA ATpase [Cryptosporidium parvum]
(551 aa)

Score: 56 bits (134), Expect: 3.6175e-06
Length: 266, Idn/Pos/Gap = 61/115/31 (22%/43%/11%)

Query: 370 QLVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQ-GQV- 427
           + + R  E + + +++ +C+  S    +YISG PGTGKT  +   +  LE    + G V 
Sbjct:  52 EFLGRANEFKEISEYIRNCISCSISGIIYISGSPGTGKTCTINRILNILENDSSKLGFVK 111

Query: 428 -PHFQYIEINGMTI----------PDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARL 476
              ++ +  N   +          P+    +  LL  +  ++      +R          
Sbjct: 112 PSSYKIVRTNASKVVSCFNKNSGLPNGISLFVHLLDLMKFQTRIIEEFKRISRNEGFQEC 171

Query: 477 LDQRFRQRRGVHNRKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIG 536
           +    +Q   + N++  +  +V +DE+D L  ++      V   F    + P S  V+I 
Sbjct: 172 IMYFMKQ---ISNKR--AKFIVFIDEID-LARSNRNHGDAVFELFKAIINFPNSGFVLIV 225

Query: 537 IANTLDLPERLLPRLASRLG----MNRQVFKPYSVTQLQQILRHKLGPQLLQHFDEDAL- 591
            +NT+ +   ++ ++   L     +   VF PYS   L+ I+  ++  +   +F  D+L 
Sbjct: 226 ASNTVQIGNEIVKKIGVNLKNKGRIKLMVFSPYSHNTLKDIVLQRI--ERASNFKNDSLL 283

Query: 592 -----ELCTRRVAAVSGDIRRALAIC 612
                ELC R+VA++ GD RR L  C
Sbjct: 284 NKAGIELCVRKVASIYGDCRRTLDAC 309

ref|YP_024035.1| origin recognition complex subunit [Picrophilus torridus DSM 9790]
gb|AAT43842.1| origin recognition complex subunit [Picrophilus torridus DSM 9790]
sp|Q6KZL0|CDC6_PICTO Cell division control protein 6 homolog (CDC6 homolog)
(408 aa)

Score: 56 bits (134), Expect: 4.06574e-06
Length: 179, Idn/Pos/Gap = 52/83/16 (29%/46%/8%)

Query: 497 LVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLLPRLASRLG 556
           L++LDE+D L+  + + +  V+   L       +E  IIGI N      +L  R+ SRL 
Sbjct: 142 LIILDEIDRLLSKNGSDSLYVILKLLG-----DTEGSIIGITNDSSFINKLDMRVRSRLN 196

Query: 557 MNRQVFKPYSVTQLQQILRHKLGPQLLQHFDED-ALELCTRRVAAVSGDIRRALAICLHA 615
               +F PY+  +L+ IL+ ++   +   F ED A+ LC    A   GD R+A+ +    
Sbjct: 197 AESIIFTPYNADELRDILKFRINGVIKNGFIEDSAINLCAAIGAQEHGDARKAIELL--- 253

Query: 616 YARSHSEDCSLRASENEHDRLVSAVDIDEAIRELTPSSVQSAVKQLSQIEQQVLMSAAL 674
             R   E C       E+   V+  DI  A      + ++ +VK L    + VL+SA L
Sbjct: 254 --RIAIEYCI-----RENRERVTIDDIYMARERFEMNILKESVKTLPIHSKMVLLSAIL 305

gb|AAV46486.1| cell division control protein 6 [Haloarcula marismortui ATCC 43049]
ref|YP_136192.1| cell division control protein 6 [Haloarcula marismortui ATCC 43049]
sp|Q5V1W6|CDC63_HALMA Cell division control protein 6 homolog 3 (CDC6 homolog 3)
(403 aa)

Score: 55 bits (133), Expect: 5.49023e-06
Length: 286, Idn/Pos/Gap = 63/118/21 (22%/41%/7%)

Query: 371 LVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHF 430
           +  R+ E    +  L   + G+  R +++ G  G GKTAV R  ++QL++   Q      
Sbjct:  26 ITAREDEISTYMAALQPIVNGAQPRNIFLYGKTGVGKTAVSRYLLKQLQRDTDQYDDVDL  85

Query: 431 QYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHNR 490
               +N   +    +    L+ +L  R    +    P       R+ D  + +   +   
Sbjct:  86 SLCWLNCTNLSSSYQVAVNLVNQLRPRDDRISTTGYP-----QQRVFDILYEELDQIG-- 138

Query: 491 KHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASR---PASELVIIGIANTLDLPERL 547
               +IL++LDE+D     H  +   +LY+     S      ++  +IGI+N     + L
Sbjct: 139 ---GTILLVLDEID-----HIGSDDEILYEIPQARSNGYLSEAKPGVIGISNDFGFRDNL 190

Query: 548 LPRLASRLGMNRQVFKPYSVTQLQQILRHKL-GPQLLQHFDEDALELCTRRVAAVSGDIR 606
            P++   L      F PY+  +L+ IL  ++ G       D+  + LC    A  +G  R
Sbjct: 191 SPKVKDTLCEEEIHFSPYNAPELRAILEERVTGAMYDDAVDDAVIALCAAIAAQDTGSAR 250

Query: 607 RALAICLHA--YARSHSEDCSLRASENEHDRLVSAVDIDEAIRELT 650
           +AL I   +   AR++ E+       ++    +    ++  +RELT
Sbjct: 251 QALDILYKSGEIARTNGEERLTEDHVHQAREKLEQSQVEHGMRELT 296

ref|NP_395848.1| Orc4 [Halobacterium sp. NRC-1]
gb|AAG20983.1| orc / cell division control protein 6; Orc4 [Halobacterium sp. NRC-1]
sp|Q9HHJ7|CD66_HALN1 Cell division control protein 6 homolog 6 (CDC6 homolog 6)
(410 aa)

Score: 55 bits (133), Expect: 5.58262e-06
Length: 303, Idn/Pos/Gap = 71/128/28 (23%/42%/9%)

Query: 370 QLVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPH 429
           ++V RD E  ++ K L   + G S   + I G  GTGK+ V +   Q+ +   Q G    
Sbjct:  38 RIVGRDEEISKLAKRLNGAVHGYSPENVMIYGKTGTGKSLVSKHVCQRAQNAAQDGVEIG  97

Query: 430 FQYIEINGMTIPDPTRAYNILLQRLG-HRSTGAAGGRRPPAPAEAARL----LDQRFRQR 484
             YI+         T+A + L  +L    STG +      + ++  +L    LD +F   
Sbjct:  98 TAYIDCAEDNT--ETQAISSLAAKLNDESSTGISVPHTGLSTSKYYKLLWKTLDAQF--- 152

Query: 485 RGVHNRKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLP 544
                     S++++LDE+D  ++N  +   ++     + A +    + +I I+N +   
Sbjct: 153 ---------DSVIIILDEID--LMNDDSVLMKL--SRAEEAGKIDCSVGVIAISNKIQYV 199

Query: 545 ERLLPRLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQHFDEDALELCTRRVAAVSGD 604
           + +  R+ S        FKPY   QL++I+ ++          ED + L     A   GD
Sbjct: 200 DNVNERVKSSFQHKELFFKPYDANQLREIMFNREDAFQDGVLSEDVIPLSAAFAAQEHGD 259

Query: 605 IRRALAICLHAYARSHSEDCSLRASENEHDRLVSAVDIDEAIREL---TPSSVQSAVKQL 661
            R+A+ I  HA   ++     L     EH R        +  REL    P+  ++A+  L
Sbjct: 260 ARKAIDILRHAGEVAYEAGAELVTE--EHVRQAQQHAEKDRFRELVNGAPTQAKAALLAL 317

Query: 662 SQI 664
           +++
Sbjct: 318 TEL 320

gb|EAL44975.1| hypothetical protein 224.t00013 [Entamoeba histolytica HM-1:IMSS]
(371 aa)

Score: 55 bits (133), Expect: 5.67656e-06
Length: 322, Idn/Pos/Gap = 69/133/69 (21%/41%/21%)

Query: 395 RCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHFQYIEINGMTIPDPTRAYNILLQRL 454
           R L+I+G PGTGKT +V     Q   ++ Q ++  F +  I   +I +  R         
Sbjct:  48 RILFINGTPGTGKTMMV-----QYLLKKHQNEITTFFFNAIKEKSIINICRK--------  94

Query: 455 GHRSTGAAGGRRPPAPAEAA--RLLDQRFRQRRGVHNRKHHSSILVLLDEMDALVLNHSA 512
                   GG +  +  E    RLL +  + + G+          +++DE D L+ +   
Sbjct:  95 -------VGGLKKSSSEEKVMERLLKRLDKIKNGI----------IVIDEYDVLMNDEGP 137

Query: 513 AAQRVLYDFLDWASRPASELVIIGIANTLDLPERLLPRLASRLGMNRQVFKPYSVTQLQQ 572
                LY F DW    +  +++I I+N     + L  R+ASR       F  Y+  +++ 
Sbjct: 138 -----LYRFFDWIFNKSPLMMLILISNNSQYSQILHSRVASRNVTFNYNFYQYTSEEIKN 192

Query: 573 ILRHKLGPQLL---------QHFDEDALELCTRRVAAVSGDIRRALAICLHAYARSHSED 623
           IL  ++G +++          +F  + +E+  +     +GD+R+AL +  +    +    
Sbjct: 193 ILLKRIGEEVIYEIFNKKDFDYFINERIEMSLQ-----NGDVRKALGMMFNILLNTKER- 246

Query: 624 CSLRASENEHDRLVSAVDIDEAIRELTPSSVQSAVKQLSQIEQQVLMSAALC-----GRQ 678
                 E   D  +S   ++E I   T +S    +   SQ+E  +L     C     G +
Sbjct: 247 -----IEKGEDIKLSHQKVNELI---TSNSSYPTLNTCSQMELIILYCIMKCKEEEYGYE 298

Query: 679 AVQQGSETFRFQQI----WHRF 696
           ++ +  +  R+++     W+ F
Sbjct: 299 SIMKYLDGIRYKKSDLINWNEF 320

dbj|BAB59911.1| origin recognition complex protein 1 [Thermoplasma volcanium GSS1]
(429 aa)

Score: 55 bits (132), Expect: 6.76366e-06
Length: 228, Idn/Pos/Gap = 58/102/23 (25%/44%/10%)

Query: 497 LVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLLPRLASRLG 556
           +++LDEMD L+      +  VL   +        ++ +IGI N   L E L  R+ SRL 
Sbjct: 164 VIVLDEMDRLIKKSGGDSLYVLLKLM--TDVENVKVSMIGITNDTTLLENLDSRIKSRLN 221

Query: 557 MNRQVFKPYSVTQLQQILRHKL----GPQLLQHFDEDALELCTRRVAAVSGDIRRALAIC 612
               VF PY+ T+++ I+  +L    GP ++   D+ A+ LC    A   GD R+A+ + 
Sbjct: 222 QESIVFPPYNATEIRDIIASRLEKVFGPGVV---DDTAINLCAAIGAQEHGDARKAIDLM 278

Query: 613 LHAYARSHSEDCSLRASENEHDRLVSAVDIDEAIRELTPSSVQSAVKQLSQIEQQVLMSA 672
             A   +  E+  L+ +E E         + EA  +   + +  A+  L    + VL+SA
Sbjct: 279 RIAIEIAIREN-RLKVTEKE---------VYEARDKYEMNVMHEAINTLPIHSKIVLLSA 328

Query: 673 ALCGRQAVQQGSETFRFQQIWHRFRQFHASTEGHPAYPLPLQDQIEEV 720
            +   Q ++  S      +I+  +R+        P  P  + D + E+
Sbjct: 329 IVT--QEIEPNSVI--TGEIYENYRRICEDLGFTPLTPRRISDLLTEL 372

ref|NP_111277.1| ATPase (AAA superfamily) [Thermoplasma volcanium GSS1]
sp|Q97AP1|CDC6_THEVO Cell division control protein 6 homolog (CDC6 homolog)
(404 aa)

Score: 55 bits (131), Expect: 8.05894e-06
Length: 228, Idn/Pos/Gap = 58/102/23 (25%/44%/10%)

Query: 497 LVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLLPRLASRLG 556
           +++LDEMD L+      +  VL   +        ++ +IGI N   L E L  R+ SRL 
Sbjct: 139 VIVLDEMDRLIKKSGGDSLYVLLKLM--TDVENVKVSMIGITNDTTLLENLDSRIKSRLN 196

Query: 557 MNRQVFKPYSVTQLQQILRHKL----GPQLLQHFDEDALELCTRRVAAVSGDIRRALAIC 612
               VF PY+ T+++ I+  +L    GP ++   D+ A+ LC    A   GD R+A+ + 
Sbjct: 197 QESIVFPPYNATEIRDIIASRLEKVFGPGVV---DDTAINLCAAIGAQEHGDARKAIDLM 253

Query: 613 LHAYARSHSEDCSLRASENEHDRLVSAVDIDEAIRELTPSSVQSAVKQLSQIEQQVLMSA 672
             A   +  E+  L+ +E E         + EA  +   + +  A+  L    + VL+SA
Sbjct: 254 RIAIEIAIREN-RLKVTEKE---------VYEARDKYEMNVMHEAINTLPIHSKIVLLSA 303

Query: 673 ALCGRQAVQQGSETFRFQQIWHRFRQFHASTEGHPAYPLPLQDQIEEV 720
            +   Q ++  S      +I+  +R+        P  P  + D + E+
Sbjct: 304 IVT--QEIEPNSVI--TGEIYENYRRICEDLGFTPLTPRRISDLLTEL 347

emb|CAA48438.1| unnamed protein product [Methanothermobacter thermautotrophicus]
pir||S26458 hypothetical protein 1' - Methanobacterium thermoformicicum plasmid pFZ1
ref|NP_039767.1| hypothetical protein pFZ1_p01 [Methanothermobacter thermautotrophicus]
sp|P29570|CDC6Z_METTF Cell division control protein 6 homolog (CDC6 homolog)
(364 aa)

Score: 54 bits (130), Expect: 1.03511e-05
Length: 303, Idn/Pos/Gap = 69/131/48 (22%/43%/15%)

Query: 374 RDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHFQYI 433
           R  E   + ++L   L G++   L I G PG+GKT   +  + +LE+      +   +YI
Sbjct:  27 RKEEVGAISQYLGYILDGATPPHLLIVGPPGSGKTVTTKYVINELEKHTSDAVI---EYI  83

Query: 434 EINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHNRKHH 493
             +G        AY +           A    R P        + ++ R+      R   
Sbjct:  84 VADGT-------AYQV-----------ATSIARAPRRGLGFLNIVEKIRE------RASE 119

Query: 494 SSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLLPR-LA 552
             +++++DE+D  +   S    ++LY      SR  + + I+G++N L + + +    + 
Sbjct: 120 GKMIIVMDEIDKTL---SRDGDKLLYHL----SREPN-VCIVGLSNKLTVMDMIGDSGVI 171

Query: 553 SRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQH-FDEDALELCTRRVAAVSGDIRRALAI 611
           S     R  F PYS  QL++IL +++         ++D + LC    A  +GD R AL +
Sbjct: 172 SSFKPRRISFAPYSAPQLEEILNYRVEMAFNDGVLEDDVVPLCAALAAQRNGDARYALDL 231

Query: 612 CLHAYARSHSEDCSLRASENEHDRLVSAVDIDEAIRELTPSSVQSAVKQLSQIEQQVLMS 671
                  S + D ++R  +     +VS  D+  A  E+    ++ +++QL    Q++L+ 
Sbjct: 232 L------SFAADIAIRQLKG----VVSESDVRMATDEVEVEFIRRSIEQLRD-NQKILLY 280

Query: 672 AAL 674
           A +
Sbjct: 281 AVM 283

ref|NP_394108.1| probable DNA polymerase II (DP2), subunit 1 [Thermoplasma acidophilum DSM 1728]
emb|CAC11775.1| probable DNA polymerase II (DP2), subunit 1 [Thermoplasma acidophilum]
sp|Q9HKG3|CDC6_THEAC Cell division control protein 6 homolog (CDC6 homolog)
(404 aa)

Score: 54 bits (129), Expect: 1.3519e-05
Length: 228, Idn/Pos/Gap = 54/105/23 (23%/46%/10%)

Query: 497 LVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLLPRLASRLG 556
           +++LDEMD L+  +   +  VL   +      +  + +IGI N   + E +  R+ SRL 
Sbjct: 139 IIILDEMDRLIKKNGGDSLYVLLKLM--TDVDSVRVSMIGITNDTTVLENIDARIKSRLN 196

Query: 557 MNRQVFKPYSVTQLQQILRHK----LGPQLLQHFDEDALELCTRRVAAVSGDIRRALAIC 612
               VF PY+ ++++ I+  +    LGP ++   D+ A+ LC    A   GD R+A+ + 
Sbjct: 197 QESIVFPPYNASEIRDIISSRLDKVLGPGVV---DDTAINLCAAIGAQEHGDARKAIDLM 253

Query: 613 LHAYARSHSEDCSLRASENEHDRLVSAVDIDEAIRELTPSSVQSAVKQLSQIEQQVLMSA 672
             A       + ++R + N+    ++  +I EA      + ++ A+  L    + VL+SA
Sbjct: 254 RIAI------EIAIRENRNK----ITENEIYEARERYEMNVLREAISTLPLHSKIVLLSA 303

Query: 673 ALCGRQAVQQGSETFRFQQIWHRFRQFHASTEGHPAYPLPLQDQIEEV 720
            +   Q ++  S      +I+  +R+        P  P  + D + E+
Sbjct: 304 VVT--QEIEPNSVI--TGEIYENYRRICDDLGFSPLSPRRISDLLTEL 347

emb|CAA48437.1| unnamed protein product [Methanothermobacter thermautotrophicus]
pir||S26448 hypothetical protein 1 - Methanobacterium thermoformicicum plasmid pFV1
ref|NP_039754.1| hypothetical protein pFV1_p02 [Methanothermobacter thermautotrophicus]
sp|P29569|CDC6V_METTF Cell division control protein 6 homolog (CDC6 homolog)
(364 aa)

Score: 54 bits (129), Expect: 1.54498e-05
Length: 303, Idn/Pos/Gap = 69/131/48 (22%/43%/15%)

Query: 374 RDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHFQYI 433
           R  E   + ++L   L G++   L I G PG+GKT   +  + +LE+      +   +YI
Sbjct:  27 RKEEVGAISQYLGYILDGATPPHLLIVGPPGSGKTVTTKYVINELEKHTSDAVI---EYI  83

Query: 434 EINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHNRKHH 493
             +G        AY +           A    R P        + ++ R+      R   
Sbjct:  84 VADGT-------AYQV-----------ATSIARAPRRGLGFLNIVEKIRE------RASE 119

Query: 494 SSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLLPR-LA 552
             +++++DE+D  +   S    ++LY      SR  + + I+G++N L + + +    + 
Sbjct: 120 GKMIIVMDEIDKTL---SRDGDKLLYHL----SREPN-VCIVGLSNKLTVMDMIGDSGVI 171

Query: 553 SRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQH-FDEDALELCTRRVAAVSGDIRRALAI 611
           S     R  F PYS  QL++IL +++         ++D + LC    A  +GD R AL +
Sbjct: 172 SSFKPRRISFAPYSAPQLEEILNYRVEMAFNDGVLEDDVVPLCAALAAQRNGDARYALDL 231

Query: 612 CLHAYARSHSEDCSLRASENEHDRLVSAVDIDEAIRELTPSSVQSAVKQLSQIEQQVLMS 671
                  S + D ++R  +     +VS  D+  A  E+    ++ +++QL    Q++L+ 
Sbjct: 232 L------SFAADIAIRQLKG----VVSESDVRMATDEVEVEFIRRSIEQLRD-NQKILLY 280

Query: 672 AAL 674
           A +
Sbjct: 281 AVM 283

ref|NP_279204.1| hypothetical protein VNG0045C [Halobacterium sp. NRC-1]
gb|AAG18684.1| Vng0045c [Halobacterium sp. NRC-1]
pir||H84164 hypothetical protein Vng0045c [imported] - Halobacterium sp. NRC-1
(471 aa)

Score: 54 bits (129), Expect: 1.55792e-05
Length: 287, Idn/Pos/Gap = 69/116/29 (24%/40%/10%)

Query: 374 RDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHFQYI 433
           RD E E+ +  L   + G     +++ G  G GKTAV    + QL+   +         I
Sbjct:  90 RDDEIEKYMDALQPVIDGWEPNNIFVYGNTGVGKTAVTDHLLDQLQTDVEAYDDVTLSVI 149

Query: 434 EINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHNRKHH 493
            +N  T+    +    L+ +L          RRP A   +     Q   ++         
Sbjct: 150 YLNCKTLSSSYQVAVELVNKL----------RRPGAEISSTGYPQQSVFKKLYQELEALG 199

Query: 494 SSILVLLDEMDALVLNHSAAAQRVLYDFLDWASR---PASELVIIGIANTLDLPERLLPR 550
            +IL++LDE+DA+          +LY+     S+     +++ IIGI+N     E+L PR
Sbjct: 200 GTILIVLDEVDAI-----GDRDDLLYELPRARSQGNLEDAKVGIIGISNDYKFQEQLDPR 254

Query: 551 LASRLGMNRQVFKPYSVTQLQQILRHKLGPQLL-QHFDEDALELCTRRVAAVSGDIRRAL 609
           +   L      F PY   +L  IL  +    +      E   + C    A  SG  R+AL
Sbjct: 255 VQDTLCERELQFPPYDALELANILDSRTDIAIADDSLAEGVTQHCAALAARDSGSARQAL 314

Query: 610 AICLHAYARSHSEDCS------LRASENEHDRLVSAVDIDEAIRELT 650
            +   A   + ++D        + A+ +E +R      ++E +RELT
Sbjct: 315 DLLRLAGELAENQDADAISTDHVEAARSELER----ERVEEGMRELT 357

sp|Q9HSW6|CD61_HALN1 Cell division control protein 6 homolog 1 (CDC6 homolog 1)
(413 aa)

Score: 54 bits (129), Expect: 1.67942e-05
Length: 287, Idn/Pos/Gap = 69/116/29 (24%/40%/10%)

Query: 374 RDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHFQYI 433
           RD E E+ +  L   + G     +++ G  G GKTAV    + QL+   +         I
Sbjct:  32 RDDEIEKYMDALQPVIDGWEPNNIFVYGNTGVGKTAVTDHLLDQLQTDVEAYDDVTLSVI  91

Query: 434 EINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHNRKHH 493
            +N  T+    +    L+ +L          RRP A   +     Q   ++         
Sbjct:  92 YLNCKTLSSSYQVAVELVNKL----------RRPGAEISSTGYPQQSVFKKLYQELEALG 141

Query: 494 SSILVLLDEMDALVLNHSAAAQRVLYDFLDWASR---PASELVIIGIANTLDLPERLLPR 550
            +IL++LDE+DA+          +LY+     S+     +++ IIGI+N     E+L PR
Sbjct: 142 GTILIVLDEVDAI-----GDRDDLLYELPRARSQGNLEDAKVGIIGISNDYKFQEQLDPR 196

Query: 551 LASRLGMNRQVFKPYSVTQLQQILRHKLGPQLL-QHFDEDALELCTRRVAAVSGDIRRAL 609
           +   L      F PY   +L  IL  +    +      E   + C    A  SG  R+AL
Sbjct: 197 VQDTLCERELQFPPYDALELANILDSRTDIAIADDSLAEGVTQHCAALAARDSGSARQAL 256

Query: 610 AICLHAYARSHSEDCS------LRASENEHDRLVSAVDIDEAIRELT 650
            +   A   + ++D        + A+ +E +R      ++E +RELT
Sbjct: 257 DLLRLAGELAENQDADAISTDHVEAARSELER----ERVEEGMRELT 299

ref|YP_134416.1| cell division control protein 6 homolog 6 [Haloarcula marismortui ATCC 43049]
gb|AAV44710.1| cell division control protein 6 homolog 6 [Haloarcula marismortui ATCC 43049]
sp|Q5V7B0|CDC6B_HALMA Cell division control protein 6 homolog 11 (CDC6 homolog 11)
(422 aa)

Score: 53 bits (127), Expect: 2.63533e-05
Length: 238, Idn/Pos/Gap = 54/95/17 (22%/39%/7%)

Query: 401 GVPGTGKTAVVRCAVQQLEQRRQQGQVPHFQYIEINGMTIPDPTRAYNILLQRLGHRSTG 460
           G  GTGKT V R   ++LE   +    P      +     PDP   Y    +++  +   
Sbjct:  76 GETGTGKTLVARHVCERLEAATEGTDSP-----IVTAYINPDPISTYTSTFRKIAEQVNA 130

Query: 461 AAGGRRPPAPAEAARLLDQRFRQRR--GVHNRKHHSSILVLLDEMDALVLNHSAAAQRVL 518
            A     P       L  + +R ++   V  R+    ++V++DE+D            VL
Sbjct: 131 KA---ENPLEVPYQGLSAEHYRDQKLWPVVQREFSGGLVVIIDEID-----KHGEVNEVL 182

Query: 519 YDFLDWASRPASE--LVIIGIANTLDLPERLLPRLASRLGMNRQVFKPYSVTQLQQILRH 576
           Y      S+   +  ++ IGI+N ++    +  R+ S L    + F PY   QL  IL +
Sbjct: 183 YTLSRTQSKDDVDFPVITIGISNDIEFKGEIESRVQSTLQPEHRTFTPYEEDQLIAILEN 242

Query: 577 KLGPQLLQHFDEDALELCTRRVAAVSGDIRRALAICLHAYARSHSEDCSLRASENEHD 634
           +         D++ +       A   GD RRA+ +  +A   +  E   +  +E+ H+
Sbjct: 243 RRDAFYDGVLDDEVIPTTAELAAEEHGDARRAVRLFRNAGEIADEEGDDIVTAEHVHE 300

ref|NP_343568.1| Cell division control 6/orc1 protein homolog  (cdc6-3) [Sulfolobus solfataricus P2]
gb|AAK42358.1| Cell division control 6/orc1 protein homolog  (cdc6-3) [Sulfolobus solfataricus P2]
sp|Q97WM8|CD63_SULSO Cell division control protein 6 homolog 3 (CDC6 homolog 3)
pir||G90387 hypothetical protein cdc6-3 [imported] - Sulfolobus solfataricus
(394 aa)

Score: 53 bits (126), Expect: 2.91286e-05
Length: 280, Idn/Pos/Gap = 69/124/37 (24%/44%/13%)

Query: 401 GVPGTGKTAVVRCAVQQLEQ-RRQQGQVPHFQYIEINGMTIPDPTRAYNILLQRLGHRST 459
           G+ GTGKT V +    ++E+ +++  +    +   +N   +    +A   +L  L  + T
Sbjct:  62 GLTGTGKTFVSKYIFNEIEEVKKEDEEYKDVKQAYVNCREVGGTPQA---VLSSLAGKLT 118

Query: 460 GAAGGRRPPAPAEAARLLDQRFRQRRGVHNRKHHSSILVLLDEMDALVLNHSAAAQRVLY 519
           G +       P     L +   + + G  N +     ++ LDE+D LV         VLY
Sbjct: 119 GFS------VPKHGINLGEYIDKIKNGTRNIR----AIIYLDEVDTLV--KRRGGDIVLY 166

Query: 520 DFLDWASRPASELVIIGIANTLDLPERLLPRLASRLGMNRQVFKPYSVTQLQQILRHKLG 579
             L    R  + + +I I+N +++ + + PR+ S LG +  +FKPY   QL+ IL     
Sbjct: 167 QLL----RSDANISVIMISNDINVRDYMEPRVLSSLGPS-VIFKPYDAEQLKFILSKYAE 221

Query: 580 PQLLQ-HFDEDALELCTRRVAAVSGDIRRALAICLHAYARS------HSEDCSLRASENE 632
             L++  +D++ L       A   GD R+A+ +   A   +        E       + E
Sbjct: 222 YGLIKGTYDDEILSYIAAISAKEHGDARKAVNLLFRAAQLASGGGIIRKEHVDKAIVDYE 281

Query: 633 HDRLVSAVDIDEAIRELTPSSVQSAVKQLSQIEQQVLMSA 672
            +RL+      EA++ L P   + A++ L  IE + +MSA
Sbjct: 282 QERLI------EAVKAL-PFHYKLALRSL--IESEDVMSA 312

gb|EAL18297.1| hypothetical protein CNBJ2200 [Cryptococcus neoformans var. neoformans B-3501A]
gb|AAW45987.1| DNA clamp loader, putative [Cryptococcus neoformans var. neoformans JEC21]
ref|XP_567504.1| DNA clamp loader, putative [Cryptococcus neoformans var. neoformans JEC21]
(834 aa)

Score: 52 bits (125), Expect: 3.93342e-05
Length: 292, Idn/Pos/Gap = 75/128/38 (25%/43%/13%)

Query: 357 RLLQVSRFGAPRVQLVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQ 416
           RL  +S + A  + +V R+ E   + ++L D      +  +Y+SG PGTGKTA+V    +
Sbjct: 384 RLCTISGYTANDM-IVGREEEKAAISQYLFD-EENDKDVGMYVSGPPGTGKTALVTAFGR 441

Query: 417 QLEQRRQQGQVPHFQYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARL 476
           Q   + +QG    ++ +E+  M +       N L  RLG        G+      +  +L
Sbjct: 442 Q---KAEQG----WRVVEVGCMGL-----KVNDLWPRLGDE---LGCGKTEEEVTKFVKL 486

Query: 477 LDQRFRQRRGVHNRKHHSSILVLLDEMDALVL-NHSAAAQRVLYDFLDWASRP--ASELV 533
                          + S IL++LDE+D+L+    S       + F    S P  +    
Sbjct: 487 ---------------NASQILIILDEVDSLMPPTPSTVPPATSHLFAKLFSLPFGSPNTK 531

Query: 534 IIGIANTLDLPERLLPRLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQHF--DEDAL 591
           +I I+NTLDL  R    L + L  +   FK Y   ++  I+  ++    +Q    D  A+
Sbjct: 532 LIAISNTLDLTIRARLVLPNGLQPSVLPFKAYGAPEISNIVNARIATANIQDIKVDSAAI 591

Query: 592 ELCTRRVAAVSGDIRRALAICLHAYARSHSEDCSLRASE-NEHDRLVSAVDI 642
            L  R+V A +GD+R  L +   A + + +E    R+   N+  R V  + +
Sbjct: 592 TLLGRKVEAQNGDLRMCLGVLGSAISLAEAEWIKKRSQAVNDPSRKVPMIKV 643

ref|NP_378161.1| hypothetical protein ST2165 [Sulfolobus tokodaii str. 7]
dbj|BAB67270.1| 386aa long conserved hypothetical protein [Sulfolobus tokodaii str. 7]
sp|Q96YK7|CDC63_SULTO Cell division control protein 6 homolog 3 (CDC6 homolog 3)
(386 aa)

Score: 52 bits (125), Expect: 3.99961e-05
Length: 253, Idn/Pos/Gap = 65/108/38 (25%/42%/15%)

Query: 401 GVPGTGKTAVVRCAVQQLEQRRQQG------QVPHFQYIEINGMTIPDPTRAYNILLQRL 454
           G+ GTGKT V R  + ++E+ +Q+       +  +    E+ G     P    + L +RL
Sbjct:  61 GLTGTGKTFVARYMLNEIEEVKQEDSDYSKVKQAYVNCREVGGT----PQAVLSALTERL 116

Query: 455 GHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHNRKHHSSILVLLDEMDALVLNHSAAA 514
                          P     L +   + +  ++ +K     LV LDE+D L+       
Sbjct: 117 ----------TTDEVPKHGINLGEYIEKIKEELNGKK----ALVYLDEVDTLI--KRRGG 160

Query: 515 QRVLYDFLDWASRPASELVIIGIANTLDLPERLLPRLASRLGMNRQVFKPYSVTQLQQIL 574
             VLY  L    R  +++ +I I+N +++ + + PR+ S LG     FKPY   QL+ IL
Sbjct: 161 DIVLYQLL----RADADISVIMISNDINIRDYMEPRVLSSLGPT-VFFKPYDAEQLKHIL 215

Query: 575 RHKLGPQLLQ-HFDEDALELCTRRVAAVSGDIRRALAICLHAYARSHSE-----DCSLRA 628
                  L +  +D++ L       A   GD R+A+ +   A   +  E     D   RA
Sbjct: 216 SIYAEYGLYRGTYDDNILSYIAAISAKEHGDARKAVNLLFRAAQLASGEGFIRKDHVDRA 275

Query: 629 -SENEHDRLVSAV 640
             E E +RL+ A+
Sbjct: 276 IIEYEQERLIEAI 288

dbj|BAD82152.1| origin recognition complex subunit 4-like [Oryza sativa (japonica cultivar-group)]
(470 aa)

Score: 52 bits (124), Expect: 5.96971e-05
Length: 87, Idn/Pos/Gap = 29/46/4 (33%/52%/4%)

Query: 493 HSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLLPRLA 552
           H +I+ +L+E D      +   QR+LY  LD      S+ V+IG++  LD  + L  R+ 
Sbjct: 189 HKTIIFVLEEFDLF----AQGKQRLLYSLLDAMQSLTSQAVVIGVSCRLDADQLLEKRVR 244

Query: 553 SRLGMNRQVFKPYSVTQLQQILRHKLG 579
           SR    + +F P SV  LQ+++ H L 
Sbjct: 245 SRFSHRKLLFVPSSVDSLQRLMEHLLA 271

dbj|BAC77041.1| origin recognition complex 4 [Oryza sativa (japonica cultivar-group)]
(425 aa)

Score: 51 bits (123), Expect: 6.48917e-05
Length: 87, Idn/Pos/Gap = 29/46/4 (33%/52%/4%)

Query: 493 HSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLLPRLA 552
           H +I+ +L+E D      +   QR+LY  LD      S+ V+IG++  LD  + L  R+ 
Sbjct: 144 HKTIIFVLEEFDLF----AQGKQRLLYSLLDAMQSLTSQAVVIGVSCRLDADQLLEKRVR 199

Query: 553 SRLGMNRQVFKPYSVTQLQQILRHKLG 579
           SR    + +F P SV  LQ+++ H L 
Sbjct: 200 SRFSHRKLLFVPSSVDSLQRLMEHLLA 226

ref|ZP_00294831.1| COG1474: Cdc6-related protein, AAA superfamily ATPase [Methanosarcina barkeri str. fusaro]
(435 aa)

Score: 50 bits (120), Expect: 0.000167991
Length: 312, Idn/Pos/Gap = 69/131/42 (22%/41%/13%)

Query: 370 QLVCRDVETERVLKFLTDCLRG--SSERCLYISGVPGTGKTAVVR-CAVQQLEQRRQQGQ 426
           +++ R+ E     +++ D  R    S   ++I G PG GKT + + C  + ++    Q +
Sbjct:  50 EILHRNEEIRLFYEYMKDIFREIPVSPGNVFIYGKPGLGKTIITKWCMTEVIKLADIQNK 109

Query: 427 VPHFQYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRG 486
             +   I IN   I    ++ + +LQ L  +     G +R       ++        R  
Sbjct: 110 --NLCVININCEKI----KSEHAVLQILNEKIPIPEGEKRKSIGNSLSK------NNRYF 157

Query: 487 VHNRKHHSS-ILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELV-----IIGIANT 540
            H   H++  I+++ DE+D       A    ++ + +    R  SEL      ++ I N 
Sbjct: 158 THLVNHYNGMIIIVFDELD------KATKPEMINNII----RTKSELTGQYPCVVCITNN 207

Query: 541 LDLPERLLPRLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQH-FDEDALELCTRRVA 599
           L+L +   P L + LG    +  PY   QLQ IL  ++      +  +E  + LC    A
Sbjct: 208 LNLIDTFPPHLQNTLGQQELIINPYDAEQLQDILNARVKTAFKPNTVEELVVPLCAAFAA 267

Query: 600 AVSGDIRRALAICLHAYARSHSEDCSLRASENEHDRLVSAVDIDEAIRELTPSSVQSAVK 659
             +GD R+A+ +      R   E      +E + + +V   D+ EA  ++  + +  A K
Sbjct: 268 QENGDARKAIELL-----RVAGE-----IAEAKGNPVVVEQDVREAKDKIELNKIIEATK 317

Query: 660 QLSQIEQQVLMS 671
           +L    +  L++
Sbjct: 318 KLPTQHKIALLA 329

ref|YP_134241.1| cell division control protein 6 [Haloarcula marismortui ATCC 43049]
gb|AAV44535.1| cell division control protein 6 [Haloarcula marismortui ATCC 43049]
(473 aa)

Score: 50 bits (120), Expect: 0.000178094
Length: 302, Idn/Pos/Gap = 65/117/26 (21%/38%/8%)

Query: 368 RVQLVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQ-RRQQGQ 426
           R ++V RD +   V+  L   L  +    L + G  GTGK+ +     +Q+    + +G 
Sbjct:  67 RDRIVGRDDQLRTVVSNLRKVLNENRPPNLLLYGPAGTGKSLIFDAVARQIRDISKNRGY 126

Query: 427 VPHFQYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAA-----RLLDQRF 481
              F  + IN   +     A   L++   H      G  R              LLD+ +
Sbjct: 127 --EFGTLRINCQNLRSLDEAVYALVREAAHDLNEEIGVARHGVSTSTKYDRLYDLLDEGY 184

Query: 482 RQRRGVHNRKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELV-----IIG 536
                        S++ +LDE+D L+   S++++    D +   SR + E +     +  
Sbjct: 185 ------------DSVVFVLDEIDLLLGRRSSSSEPAYSDLIYQLSRASIESIDIQVSVAA 232

Query: 537 IANTLDLPERLLPRLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQHFDEDALELCTR 596
           + N  +    L  R  S        F  Y   QLQ+ILR++    +     ED + L + 
Sbjct: 233 LTNDPEFMNNLDARAESSFNPRDIPFSDYDANQLQEILRNREDAFIQDALSEDVIPLTSA 292

Query: 597 RVAAVSGDIRRALAICLHAYARSHSEDCSLRASENEHDRLVSAVDIDEAIRELTPSSVQS 656
             A   GD R+A+ + L       +E+  L  +EN        V+ D +++ +   + Q 
Sbjct: 293 FAAQSHGDARKAIDL-LRKAGDVANENGDLTVTENHVREAQEDVETDRSLKLVEGLTTQK 351

Query: 657 AV 658
            +
Sbjct: 352 KI 353

emb|CAB80573.1| ES43 like protein [Arabidopsis thaliana]
emb|CAB38830.1| ES43 like protein [Arabidopsis thaliana]
pir||H85462 ES43 like protein [imported] - Arabidopsis thaliana
pir||T06070 ES43 protein homolog F19H22.200 - Arabidopsis thaliana  (fragment)
(258 aa)

Score: 50 bits (118), Expect: 0.000268046
Length: 114, Idn/Pos/Gap = 30/56/18 (26%/49%/15%)

Query: 106 WIAQILKISRESTGNDERILVKWFYRMKDLY----HWHTTVGHEEVFESEHLDENESDCV 161
           ++A++  I  ++ G+  ++ V+W+YR ++       +H   G +EVF S+H D   +D +
Sbjct:  41 YVARVEAIETDARGSHAKVRVRWYYRPEESIGGRRQFH---GAKEVFLSDHFDFQSADTI  97

Query: 162 VGRCHIVCEMEWRMLLEKRTRSSSVSKQEELRVFLCRERYDFITGSFAPSTMTI 215
            G+C +             T+  SV   +    F CR  Y+  TG+F P  +T+
Sbjct:  98 EGKCKV-------HSFSSYTKLDSVGNDD----FFCRFEYNSTTGAFDPDRVTV 140

sp|Q5V7E8|CDC6A_HALMA Cell division control protein 6 homolog 10 (CDC6 homolog 10)
(431 aa)

Score: 50 bits (118), Expect: 0.000296273
Length: 299, Idn/Pos/Gap = 65/117/20 (21%/39%/6%)

Query: 368 RVQLVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQ-RRQQGQ 426
           R ++V RD +   V+  L   L  +    L + G  GTGK+ +     +Q+    + +G 
Sbjct:  25 RDRIVGRDDQLRTVVSNLRKVLNENRPPNLLLYGPAGTGKSLIFDAVARQIRDISKNRGY  84

Query: 427 VPHFQYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAA--RLLDQRFRQR 484
              F  + IN   +     A   L++   H      G  R          RL D      
Sbjct:  85 --EFGTLRINCQNLRSLDEAVYALVREAAHDLNEEIGVARHGVSTSTKYDRLYDLL---- 138

Query: 485 RGVHNRKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELV-----IIGIAN 539
                 + + S++ +LDE+D L+   S++++    D +   SR + E +     +  + N
Sbjct: 139 -----DEGYDSVVFVLDEIDLLLGRRSSSSEPAYSDLIYQLSRASIESIDIQVSVAALTN 193

Query: 540 TLDLPERLLPRLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQHFDEDALELCTRRVA 599
             +    L  R  S        F  Y   QLQ+ILR++    +     ED + L +   A
Sbjct: 194 DPEFMNNLDARAESSFNPRDIPFSDYDANQLQEILRNREDAFIQDALSEDVIPLTSAFAA 253

Query: 600 AVSGDIRRALAICLHAYARSHSEDCSLRASENEHDRLVSAVDIDEAIRELTPSSVQSAV 658
              GD R+A+ + L       +E+  L  +EN        V+ D +++ +   + Q  +
Sbjct: 254 QSHGDARKAIDL-LRKAGDVANENGDLTVTENHVREAQEDVETDRSLKLVEGLTTQKKI 311

ref|NP_916954.1| P0445E10.5 [Oryza sativa (japonica cultivar-group)]
(716 aa)

Score: 50 bits (118), Expect: 0.000303783
Length: 87, Idn/Pos/Gap = 29/46/4 (33%/52%/4%)

Query: 493 HSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLLPRLA 552
           H +I+ +L+E D      +   QR+LY  LD      S+ V+IG++  LD  + L  R+ 
Sbjct: 506 HKTIIFVLEEFDLF----AQGKQRLLYSLLDAMQSLTSQAVVIGVSCRLDADQLLEKRVR 561

Query: 553 SRLGMNRQVFKPYSVTQLQQILRHKLG 579
           SR    + +F P SV  LQ+++ H L 
Sbjct: 562 SRFSHRKLLFVPSSVDSLQRLMEHLLA 588

gb|AAH67614.1| Zgc:85772 [Danio rerio]
ref|NP_998348.1| origin recognition complex subunit 4 [Danio rerio]
(432 aa)

Score: 50 bits (118), Expect: 0.000308895
Length: 350, Idn/Pos/Gap = 82/148/49 (23%/42%/14%)

Query: 370 QLVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPH 429
           Q +  D + + +L+ L           + I G  G+GKT ++ C +++L   ++  +  +
Sbjct:  34 QPIGLDSQYKHLLELLRRTAVHGESNSVLIVGPRGSGKTMLLGCVLRELMSLKEVQK--N  91

Query: 430 FQYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHN 489
              +E+NG+   D   A   + ++L        G +   + AE    L +  ++     +
Sbjct:  92 VLLVELNGLLQTDDKIALKEITRQL--HLENVVGDKVFGSFAENLAFLLEALKK----GD 145

Query: 490 RKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLLP 549
           +     +L LLDE D L  +H    Q +LY+ LD +    + + ++G    LD+ E L  
Sbjct: 146 KSSSRPVLFLLDEFD-LFAHHKN--QTLLYNLLDVSQSAQTPVAVVGFTCRLDVLELLEK 202

Query: 550 RLASRLGMNRQV--FKPYSVTQLQQILRHKLG-PQ------LLQHFDEDALELCT----- 595
           R+ SR   +RQ+  F   S +Q   ++R +L  PQ          +++   +LC      
Sbjct: 203 RVKSRFS-HRQIHLFSSLSFSQYVDVVRLQLSLPQDFPDHRFSSQWNQSVTKLCEDKSVL 261

Query: 596 ---RRVAAVSGDIRRALAICLHAYAR---SHSEDCSLRASENEHDRLVSAVDIDEAIREL 649
              +R    S D R   ++   A +R   SHS  C   A   E  RL+SA          
Sbjct: 262 EVLKRSFNSSKDFRSLFSLLFMAVSRVSVSHSTLC--EADFLESGRLISA---------- 309

Query: 650 TPSSVQSAVKQLSQIEQQVLMSAALCGRQAVQQGSETFRFQQIWHRFRQF 699
              S  + +  LS +E  +++  A+        G E F FQ + + F++F
Sbjct: 310 --DSKANVLHGLSILELCLII--AMKHLNDTYDG-EPFNFQMVHNEFKKF 354

gb|AAV48219.1| cell division control protein 6 homolog 1 [Haloarcula marismortui ATCC 43049]
ref|YP_137925.1| cell division control protein 6 homolog 1 [Haloarcula marismortui ATCC 43049]
sp|Q5UWY4|CDC66_HALMA Cell division control protein 6 homolog 6 (CDC6 homolog 6)
(412 aa)

Score: 49 bits (117), Expect: 0.000358952
Length: 338, Idn/Pos/Gap = 73/134/45 (21%/39%/13%)

Query: 371 LVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHF 430
           +V RD E E     L   + G     ++I G  G GKTAV    + +L +     +V   
Sbjct:  27 IVGRDNEIEEYEAALQPIINGEYPDNIFIYGKTGVGKTAVTNFLLNELRESADHFEV-DL  85

Query: 431 QYIEINGMTIPDPTRAYNILLQRL-GHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHN 489
             I +N   +    +A   L+  L GH +  A  G      ++  RLL     +  G   
Sbjct:  86 TVISLNCDGLSTSYQAAISLVNNLRGHENHIAETGH---PQSKVYRLLWNELNKLSG--- 139

Query: 490 RKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPAS-------ELVIIGIANTLD 542
                S++++LDE+D +  +           FL   +R  +       +L +IGI+N   
Sbjct: 140 -----SVIIVLDEIDHITDD----------TFLYQITRADNNGYIDNIQLGVIGISNDST 184

Query: 543 LPERLLPRLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQHFDEDA-LELCTRRVAAV 601
             E+L  ++ S L      F PY   +LQ++L  +      +   ED  + LC       
Sbjct: 185 FREQLDAKVQSSLCETEISFPPYGTEELQKVLEQRAEIAFHESALEDGVIPLCAALGRQD 244

Query: 602 SGDIRRALAICLHAYARSHSEDCSLRASENEHDRLVSAVDIDEAIRELTPSSVQSAVKQL 661
            GD RRA+ +   A   + +E+ +   +++          ++ A  +L        ++ L
Sbjct: 245 GGDARRAITLLRKAGDLARTENANSVTTDH----------VERAQEKLEAQQSMDIMRDL 294

Query: 662 SQIEQQVLMSAALCGRQAVQQGSETFRFQQIWHRFRQF 699
           ++ EQ  L +          +G    R + ++ R+++ 
Sbjct: 295 TEHEQLTLYALT----TLAAEGETPARSRIVYQRYKEL 328

gb|AAL85127.1| putative ES43 protein [Arabidopsis thaliana]
gb|AAK93611.1| putative ES43 protein [Arabidopsis thaliana]
ref|NP_568053.1| PHD finger family protein / bromo-adjacent homology (BAH) domain-containing protein [Arabidopsis thaliana]
gb|AAG21353.1| putative PHD finger transcription factor [Arabidopsis thaliana]
(228 aa)

Score: 48 bits (114), Expect: 0.000735648
Length: 111, Idn/Pos/Gap = 29/54/12 (26%/48%/10%)

Query: 106 WIAQILKISRESTGNDERILVKWFYRMKDLYHWHTTV-GHEEVFESEHLDENESDCVVGR 164
           ++A++  I  ++ G+  ++ V+W+YR ++         G +EVF S+H D   +D + G+
Sbjct:  41 YVARVEAIETDARGSHAKVRVRWYYRPEESIGGRRQFHGAKEVFLSDHFDFQSADTIEGK 100

Query: 165 CHIVCEMEWRMLLEKRTRSSSVSKQEELRVFLCRERYDFITGSFAPSTMTI 215
           C +             T+  SV   +    F CR  Y+  TG+F P  +T+
Sbjct: 101 CKV-------HSFSSYTKLDSVGNDD----FFCRFEYNSTTGAFDPDRVTV 140

gb|AAM66132.1| ES43 like protein [Arabidopsis thaliana]
(228 aa)

Score: 48 bits (114), Expect: 0.000754294
Length: 111, Idn/Pos/Gap = 29/55/12 (26%/49%/10%)

Query: 106 WIAQILKISRESTGNDERILVKWFYRMKDLYHWHTTV-GHEEVFESEHLDENESDCVVGR 164
           ++A++  I  ++ G+  ++ V+W+YR ++         G +EVF S+H D   +D + G+
Sbjct:  41 YVARVEAIETDARGSHAKVRVRWYYRPEESIGGRRQFHGAKEVFLSDHFDFQSADTIEGK 100

Query: 165 CHIVCEMEWRMLLEKRTRSSSVSKQEELRVFLCRERYDFITGSFAPSTMTI 215
           C +     +       T+  SV   +    F CR  Y+  TG+F P  +T+
Sbjct: 101 CKVHSFTSY-------TKLDSVGNDD----FFCRFEYNSTTGAFDPDRVTV 140

emb|CAG79595.1| unnamed protein product [Yarrowia lipolytica CLIB99]
ref|XP_504002.1| hypothetical protein [Yarrowia lipolytica]
(511 aa)

Score: 48 bits (114), Expect: 0.000754294
Length: 207, Idn/Pos/Gap = 51/87/7 (24%/42%/3%)

Query: 375 DVETERVLKFLTDCLR-GSSERCLYISGVPGTGKTAVVRCAVQQLEQR-RQQGQVPHFQY 432
           D E  RV   + + +R G    C+ I G  GTGKT +V  A+ +LE++    G   +F  
Sbjct:  74 DGEKARVYSLMENAIRFGEGNSCI-IVGPRGTGKTLIVESALTELEEKYNSAGSQNNFIT 132

Query: 433 IEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHNRKH 492
           I ++G    D   A   + ++L              + +E    +   F +     + K 
Sbjct: 133 IRLSGYAQTDDKMAVREIARQLDTVLLNQGQLIENKSISETLNQILSLFDRADIDESEKE 192

Query: 493 HSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLLPRLA 552
             S++ +LDE D      S   Q +LY   D A    + + +IG+   ++  E L  R+ 
Sbjct: 193 TVSLVFILDEFDRFC---STTKQTLLYTLFDVAQSSRAPIAVIGLTPRINARELLEKRVR 249

Query: 553 SRLGMN-RQVFKPYSVTQLQQILRHKL 578
           SR      QV + + +     ILR+ +
Sbjct: 250 SRFSQRVVQVKRQHGMNDFWAILRNAV 276

gb|AAH74668.1| Origin recognition complex, subunit 4-like [Xenopus tropicalis]
ref|NP_001005654.1| origin recognition complex, subunit 4-like [Xenopus tropicalis]
(432 aa)

Score: 48 bits (113), Expect: 0.000960786
Length: 343, Idn/Pos/Gap = 79/142/55 (23%/41%/16%)

Query: 389 LRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHFQYIEINGMTIPDPTRAYN 448
           + G S   L I G  G+GK+ +++ A++++   +Q  +  +   + +NG+       A  
Sbjct:  54 VHGESNSALII-GPRGSGKSMLLKGALEEILAMKQVKE--NALQVRLNGLLQTTDKIALK 110

Query: 449 ILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHNRKHHSSILVLLDEMDALVL 508
            + ++L        G R   + AE    L +  +      +RK    +L LLDE D L  
Sbjct: 111 EITRQL--HLENVVGDRVFGSFAENLAFLLEALK----TGDRKSSCPVLFLLDEFD-LFA 163

Query: 509 NHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLLPRLASRLGMNRQV--FKPYS 566
           +H    Q +LY+  D A    + + +IG+   LD+ E L  R+ SR   +RQ+     +S
Sbjct: 164 HHKN--QTLLYNLFDIAQSAQTPVAVIGLTCRLDVMELLEKRVKSRFS-HRQIHLLNSFS 220

Query: 567 VTQLQQILRHKL-------GPQLLQHFDEDALELCTRRVA--------AVSGDIRR---- 607
             Q  +I + KL         Q  + ++E    L   ++         + S D+R     
Sbjct: 221 FIQYLEIFQEKLFLPASFPDSQFAEKWNESIKSLVESKMVEDILQKQYSASKDVRSLHML 280

Query: 608 -ALAICLHAYARSHSEDCSLRASENEHDRLVSAVDIDEAIRELTPSSVQSAVKQLSQIEQ 666
             LA+C  + +  H                ++A D  E  R     S  + +  LS +E 
Sbjct: 281 LLLAVCRVSVSHPH----------------ITAADFLEVFRLRNQDSKANIMHGLSVLEL 324

Query: 667 QVLMSAALCGRQAVQQGSETFRFQQIWHRFRQFHASTEGHPAY 709
            +++  A+   Q +  G E F FQ + + F++F    + H  Y
Sbjct: 325 CLII--AMKHLQDIYDG-EPFNFQMVHNEFQKF-IQRKAHSVY 363

emb|CAA76187.1| origin recognition complex subunit 4 [Xenopus laevis]
sp|O93479|ORC4_XENLA Origin recognition complex subunit 4
(432 aa)

Score: 48 bits (113), Expect: 0.00111648
Length: 338, Idn/Pos/Gap = 78/138/45 (23%/40%/13%)

Query: 389 LRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHFQYIEINGMTIPDPTRAYN 448
           + G S   L I G  G+GK+ +++ A++ +   +Q  +      + +NG+       A  
Sbjct:  54 IHGESNSALII-GPRGSGKSMLLKGALEDIFGMKQMKETA--LQVNLNGLLQTTDKIALK 110

Query: 449 ILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHNRKHHSSILVLLDEMDALVL 508
            + ++L        G R   + AE    L +  +      +RK    +L +LDE D L  
Sbjct: 111 EITRQL--HLENVVGDRVFGSFAENLSFLLEALK----TGDRKSSCPVLFVLDEFD-LFA 163

Query: 509 NHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLLPRLASRLGMNRQV--FKPYS 566
           +H    Q +LY+  D A    + + +IG+   LD+ E L  R+ SR   +RQ+     +S
Sbjct: 164 HHKN--QTLLYNLFDIAQSAQTPVAVIGLTCRLDVMELLEKRVKSRFS-HRQIHLLNSFS 220

Query: 567 VTQLQQILRHKLG-------PQLLQHFDEDALELCTRRVAA--------VSGDIRRALAI 611
            +Q  QI + KL         Q  + ++E    L   ++           S D+R    +
Sbjct: 221 FSQYLQIFQEKLSLPASFPDSQFAEKWNESIKSLVESKLVEDVLQKQYNASKDVRSLHML 280

Query: 612 CLHAYARSHSEDCSLRASENEHDRLVSAVDIDEAIRELTPSSVQSAVKQLSQIEQQVLMS 671
            L A  R            N     ++A D  E  R     S  + +  +S +E  +++ 
Sbjct: 281 MLLAVCRV-----------NVSHPHITAADFLEVFRLRNQDSKANILHGVSVLELCLII- 328

Query: 672 AALCGRQAVQQGSETFRFQQIWHRFRQFHASTEGHPAY 709
            A+   Q +  G E F FQ + + F++F    + H  Y
Sbjct: 329 -AMKHLQDIYDG-EPFNFQMVHNEFQKF-IQRKAHSVY 363

emb|CAE01428.1| origin recognition complex 4 subunit [Arabidopsis thaliana]
(417 aa)

Score: 48 bits (113), Expect: 0.00114478
Length: 86, Idn/Pos/Gap = 28/44/4 (32%/51%/4%)

Query: 493 HSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLLPRLA 552
           H +I+ +LDE D      +   QR+LY  LD      S+ V++GI++ LD  + L  R+ 
Sbjct: 140 HKTIIFVLDEFDMF----AQGKQRLLYSLLDAMQSVTSQAVVVGISSRLDADQLLEKRVR 195

Query: 553 SRLGMNRQVFKPYSVTQLQQILRHKL 578
           SR    + +F P S  +L  +  H L
Sbjct: 196 SRFSHRKFLFLPPSREELDGLFVHLL 221

emb|CAE52912.1| putative origin recognition complex subunit 4 [Arabidopsis thaliana]
(442 aa)

Score: 48 bits (113), Expect: 0.00115437
Length: 86, Idn/Pos/Gap = 28/44/4 (32%/51%/4%)

Query: 493 HSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLLPRLA 552
           H +I+ +LDE D      +   QR+LY  LD      S+ V++GI++ LD  + L  R+ 
Sbjct: 140 HKTIIFVLDEFDMF----AQGKQRLLYSLLDAMQSVTSQAVVVGISSRLDADQLLEKRVR 195

Query: 553 SRLGMNRQVFKPYSVTQLQQILRHKL 578
           SR    + +F P S  +L  +  H L
Sbjct: 196 SRFSHRKFLFLPPSREELDGLFVHLL 221

ref|ZP_00305991.1| COG1474: Cdc6-related protein, AAA superfamily ATPase [Ferroplasma acidarmanus]
(422 aa)

Score: 47 bits (112), Expect: 0.00135268
Length: 304, Idn/Pos/Gap = 69/125/34 (22%/41%/11%)

Query: 374 RDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHFQYI 433
           R+ + + + + L+  + G     L + G  G+GKT+ V      L++  +     +   I
Sbjct:  34 REKQIDSIARVLSSIVTGGLSSNLLLYGKSGSGKTSSVIYVTGMLKETLKG----NINII  89

Query: 434 EINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHNRKHH 493
            IN   I D    Y+IL+      ++G A     P P          F   + ++    +
Sbjct:  90 YIN-CEIYDSQ--YSILVYLTNAINSGDA-----PIPILGLPQDKIYFELVKRLNKSGRY 141

Query: 494 SSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLLPRLAS 553
           +  +++LDE+D L+    + A  VL   +       S   +IGI N       L  R+ S
Sbjct: 142 T--VIILDEIDKLIQKSGSDALYVLLKIM-----ADSNTSLIGITNDASFVNALDARVQS 194

Query: 554 RLGMNRQVFKPYSVTQLQQILRHKLGPQLLQHF-DEDALELCTRRVAAVSGDIRRALAIC 612
           RL     +F PY+  +L+ IL  ++   +   F  E ++ LC    A   GD R+++ + 
Sbjct: 195 RLNQESIIFPPYNAMELRDILNFRVSGIIKDGFITEASINLCAALGAQEHGDARKSIDLL 254

Query: 613 LHAY--ARSHSEDCSLRASENEHDRLVSAVDIDEAIRELTPSSVQSAVKQLSQIEQQVLM 670
             A   A    +DC            V+  D+  A      + ++ +++ L    + VL+
Sbjct: 255 RIAIDSALKDGKDC------------VTIDDVYLARDRFEMNVLKESIRTLPIHSKMVLL 302

Query: 671 SAAL 674
           SA L
Sbjct: 303 SACL 306

gb|EAA58401.1| hypothetical protein AN5892.2 [Aspergillus nidulans FGSC A4]
ref|XP_410029.1| hypothetical protein AN5892.2 [Aspergillus nidulans FGSC A4]
(742 aa)

Score: 47 bits (112), Expect: 0.00148271
Length: 201, Idn/Pos/Gap = 47/84/15 (23%/41%/7%)

Query: 375 DVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPHFQYIE 434
           D E  +V + +   +       + + G  G GKTA++   V  L+Q  +      F  + 
Sbjct: 299 DTEYLKVHQLIEQTVTFGEGNSMLLLGSRGAGKTAIIESIVSSLKQEHKN----DFHVVR 354

Query: 435 INGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAAR----LLDQRFRQRRGVHNR 490
           +NG    D   A   + ++LG  +       +  + A+       LL      +    N+
Sbjct: 355 LNGFLHTDDRLALREIWRQLGRETNTEEEAGKVTSYADTMATLLALLSHPEELQASADNQ 414

Query: 491 KHHS---SILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERL 547
              +   SI+++LDE D  V   +   Q +LY+  D A    + L ++G+   +D+ E L
Sbjct: 415 NGTTTAKSIVIVLDEFDLFV---THPRQTLLYNLFDIAQARKAPLAVLGVTTKVDVTEML 471

Query: 548 LPRLASRLGMNRQVFKPYSVT 568
             R+ SR   +R V+ P   T
Sbjct: 472 EKRVKSRFS-HRSVYVPLPRT 491

ref|NP_909931.1| putative DNA-binding protein [Oryza sativa (japonica cultivar-group)]
gb|AAO37525.1| putative DNA-binding protein [Oryza sativa (japonica cultivar-group)]
(218 aa)

Score: 46 bits (109), Expect: 0.00319471
Length: 114, Idn/Pos/Gap = 33/57/17 (28%/50%/14%)

Query: 106 WIAQILKISRESTG---NDERILVKWFYRMKDLYHWHTTV-GHEEVFESEHLDENESDCV 161
           ++A++ +I  E+TG   +  +I V+W+YR ++         G +EVF S+H D   +D +
Sbjct:  42 YVARVEEI--EATGPQASQVKIKVRWYYRPEESIGGRRPFHGSKEVFLSDHYDSQSADTI  99

Query: 162 VGRCHIVCEMEWRMLLEKRTRSSSVSKQEELRVFLCRERYDFITGSFAPSTMTI 215
            G+C++             T+  SVS ++    F CR  Y   TGSF P  + +
Sbjct: 100 EGKCYV-------HTFRDYTKLRSVSAED----FFCRFEYKSATGSFVPDRIAV 142

ref|NP_069529.1| hypothetical protein AF0695 [Archaeoglobus fulgidus DSM 4304]
gb|AAB90547.1| conserved hypothetical protein [Archaeoglobus fulgidus DSM 4304]
pir||G69336 conserved hypothetical protein AF0695 - Archaeoglobus fulgidus
sp|O29563|CD62_ARCFU Cell division control protein 6 homolog 2 (CDC6 homolog 2)
(376 aa)

Score: 46 bits (109), Expect: 0.0035018
Length: 304, Idn/Pos/Gap = 64/127/42 (21%/41%/13%)

Query: 370 QLVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPH 429
           +L+ RD +  +++  +   +  SS    +  G P TGKT+ +R  +++ E  R+ G +  
Sbjct:  38 ELLFRDGQIRQLVSCIKPAMLNSSPINAFCLGPPSTGKTSTIRYVLREAE--RETGLL--  93

Query: 430 FQYIEINGMTIPDPTRAYNILLQRLGHRSTGAAGGRRPPAPAEAARLLDQRFRQRRGVHN 489
           + YI I      +P + ++ + Q +        G + PP+      L+D+ +        
Sbjct:  94 YSYIRIP--RFKEPYKVFSKIFQDV-------LGQQSPPSGISKTVLMDRVWSNL----- 139

Query: 490 RKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLLP 549
                 +LV+LD+++ L  N+   A  +LY+ L        ++ I+  A  +  P  L P
Sbjct: 140 ---DEPLLVVLDDINFLGKNY---ANEILYEILKAPDEYGVKVGIVAAATDVKFPLLLDP 193

Query: 550 RLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQH-FDEDALELCTRRVAAV---SGDI 605
            + +        +  Y   +++ ILR ++     +  FD+ A     RRV  +   + D+
Sbjct: 194 FVGASFHYMEIHYPSYGYAEIEGILRKRVEHGFYEGVFDDGAF----RRVVELAYRASDV 249

Query: 606 RRALAICLHAYARSHSEDCSLRASENEHDRLVSAVDIDEAIRELTPSSVQSAVKQLSQIE 665
           R  + +   A   + S     R S    +R V      E++     S +   +  L+  E
Sbjct: 250 RYGIYLLKAAGMNAES-----RGSRKVEERDVEVAHAGESL-----SFIAKILTALNSEE 299

Query: 666 QQVL 669
           + VL
Sbjct: 300 RAVL 303

gb|AAL10455.1| origin recognition complex subunit 4 [Zea mays]
(422 aa)

Score: 46 bits (108), Expect: 0.00374352
Length: 86, Idn/Pos/Gap = 27/45/4 (31%/52%/4%)

Query: 493 HSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLLPRLA 552
           H +IL +L+E D      +   QR+LY  LD      S+ V+IG++  LD  + L  R+ 
Sbjct: 141 HKTILFILEEFDLF----AQGKQRLLYSLLDAMQSLTSQAVVIGVSCRLDADQLLEKRVR 196

Query: 553 SRLGMNRQVFKPYSVTQLQQILRHKL 578
           SR    + +F   S+  +Q+++ H L
Sbjct: 197 SRFSHRKLLFISPSLDDMQRLVEHLL 222

ref|YP_134157.1| cell division control protein 6 [Haloarcula marismortui ATCC 43049]
gb|AAV44451.1| cell division control protein 6 [Haloarcula marismortui ATCC 43049]
sp|Q5V7I2|CDC69_HALMA Cell division control protein 6 homolog 9 (CDC6 homolog 9)
(408 aa)

Score: 46 bits (108), Expect: 0.00374352
Length: 214, Idn/Pos/Gap = 49/97/23 (22%/45%/10%)

Query: 495 SILVLLDEMDALVLNHSAAAQRVLYDFLDWASR---PASELVIIGIANTLDLPERLLPRL 551
           +IL++LDE+D++          +LY+     +     ++++ +IGI+N     ++L PR+
Sbjct: 140 TILIVLDEVDSI-----GDRDELLYELPRARANGNLDSAKVGVIGISNDFKFRDQLDPRV 194

Query: 552 ASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQ-HFDEDALELCTRRVAAVSGDIRRALA 610
              L      F PY  T+L+ IL  ++   +     D   L+LC    A  SG  R+AL 
Sbjct: 195 QDTLCERELQFPPYDATELKNILESRVEVAVTDGSTDTGVLQLCAALAARDSGSARQALD 254

Query: 611 ICLHAYARSHSEDCSLRASENEHDRLVSAVDIDEAIRELTPSSVQSAVKQLSQIEQQVLM 670
           +      R   E      +EN    ++    I++A  +L    V+  +++L+   +  L+
Sbjct: 255 LL-----RLGGE-----IAENREAEMIKEGHIEDARSQLEQERVEEGMRELTTHGRLALL 304

Query: 671 SAALCGRQAVQQGSETFRFQQIWHRFRQFHASTE 704
             A+  + A ++     R + ++  +R    S+E
Sbjct: 305 --AVISKAAKEE--TPCRTRDLYEEYRSLCESSE 334

gb|AAT37464.2| origin recognition complex protein 4 [Arabidopsis thaliana]
(383 aa)

Score: 46 bits (108), Expect: 0.00457349
Length: 86, Idn/Pos/Gap = 28/43/4 (32%/50%/4%)

Query: 493 HSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLPERLLPRLA 552
           H +I+ +LDE D      +A    VLY  LD      S+ V++GI++ LD  + L  R+ 
Sbjct: 140 HKTIIFVLDEFDMFAQGKAA----VLYSLLDAMQSVTSQAVVVGISSRLDADQLLEKRVR 195

Query: 553 SRLGMNRQVFKPYSVTQLQQILRHKL 578
           SR    + +F P S  +L  +  H L
Sbjct: 196 SRFSHRKFLFLPPSREELDGLFVHLL 221

ref|XP_476919.1| putative ES43 protein [Oryza sativa (japonica cultivar-group)]
dbj|BAC79935.1| putative ES43 protein [Oryza sativa (japonica cultivar-group)]
dbj|BAD30193.1| putative ES43 protein [Oryza sativa (japonica cultivar-group)]
(218 aa)

Score: 45 bits (107), Expect: 0.00488919
Length: 100, Idn/Pos/Gap = 29/48/12 (29%/48%/12%)

Query: 117 STGNDERILVKWFYRMKDLYHWHTTV-GHEEVFESEHLDENESDCVVGRCHIVCEMEWRM 175
           S G + R+ V+W+YR ++         G +EVF S+H D   +D + G+C++        
Sbjct:  53 SRGTNVRVRVRWYYRPEESMGGRRPFHGAKEVFLSDHYDVQSADTIEGKCNV-------H 105

Query: 176 LLEKRTRSSSVSKQEELRVFLCRERYDFITGSFAPSTMTI 215
                T+  SV+ ++    F CR  Y   TGSF P  + +
Sbjct: 106 SFRSYTKLDSVNAED----FFCRFEYKSATGSFVPDRIAV 141

sp|Q5V385|CDC61_HALMA Cell division control protein 6 homolog 1 (CDC6 homolog 1)
(416 aa)

Score: 45 bits (107), Expect: 0.00497147
Length: 95, Idn/Pos/Gap = 32/52/12 (33%/54%/12%)

Query: 534 IIGIANTLDLPERLLPRLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQHFDEDAL-E 592
           II I+N ++  E++  R+ S LG N  +F PY   QL+QIL ++        F ED L  
Sbjct: 195 IISISNKVNFREQMTERVKSSLGHNEMIFDPYDGEQLRQILENR-----KDAFQEDILMP 249

Query: 593 LCTRRVAAVS----GDIRRALAICLHA--YARSHS 621
               + AA++    GD R+A+ +  HA  YA++++
Sbjct: 250 GVIPKTAALAAQRHGDARKAIRLLRHAGDYAKTNN 284

gb|AAV46017.1| cell division control protein 6 homolog 6 [Haloarcula marismortui ATCC 43049]
ref|YP_135723.1| cell division control protein 6 homolog 6 [Haloarcula marismortui ATCC 43049]
(424 aa)

Score: 45 bits (107), Expect: 0.00497147
Length: 95, Idn/Pos/Gap = 32/52/12 (33%/54%/12%)

Query: 534 IIGIANTLDLPERLLPRLASRLGMNRQVFKPYSVTQLQQILRHKLGPQLLQHFDEDAL-E 592
           II I+N ++  E++  R+ S LG N  +F PY   QL+QIL ++        F ED L  
Sbjct: 203 IISISNKVNFREQMTERVKSSLGHNEMIFDPYDGEQLRQILENR-----KDAFQEDILMP 257

Query: 593 LCTRRVAAVS----GDIRRALAICLHA--YARSHS 621
               + AA++    GD R+A+ +  HA  YA++++
Sbjct: 258 GVIPKTAALAAQRHGDARKAIRLLRHAGDYAKTNN 292

ref|NP_395700.1| Orc2 [Halobacterium sp. NRC-1]
gb|AAG20835.1| orc / cell division control protein 6; Orc2 [Halobacterium sp. NRC-1]
(264 aa)

Score: 45 bits (106), Expect: 0.00665751
Length: 210, Idn/Pos/Gap = 50/93/23 (23%/44%/10%)

Query: 370 QLVCRDVETERVLKFLTDCLRGSSERCLYISGVPGTGKTAVVRCAVQQLEQRRQQGQVPH 429
           ++V RD E  ++ K L   + G S   + I G  GTGK+ V +   Q+ +   Q G    
Sbjct:  38 RIVGRDEEISKLAKRLNGAVHGYSPENVMIYGKTGTGKSLVSKHVCQRAQNAAQDGVEIG  97

Query: 430 FQYIEINGMTIPDPTRAYNILLQRLGHR-STGAAGGRRPPAPAEAARL----LDQRFRQR 484
             YI+         T+A + L  +L +  STG +      + ++  +L    LD +F   
Sbjct:  98 TAYIDCAEDNT--ETQAISSLAAKLNNESSTGISVPHTGLSTSKYYKLLWKTLDAQF--- 152

Query: 485 RGVHNRKHHSSILVLLDEMDALVLNHSAAAQRVLYDFLDWASRPASELVIIGIANTLDLP 544
                     S++++LDE+D  ++N  +   ++     + A +    + +I I+N +   
Sbjct: 153 ---------DSVIIILDEID--LMNDDSVLMKL--SRAEEAGKIDCSVGVIAISNKIQYV 199

Query: 545 ERLLPRLASRLGMNRQVFKPYSVTQLQQIL 574
           + +  R+ S        FKPY   QL++I+
Sbjct: 200 DNVNERVKSSFQHKELFFKPYDANQLREIM 229

Cyanidioschyzon merolae Genome Project