Cyanidioschyzon merolae Genome Project

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CMS347C (231 aa)
by blastp 2.2.10 [Oct-19-2004] against nr [Apr-30-2005] (XML result)


similar to Homo sapiens (Human). MAD2-like protein 1 [Dictyostelium discoideum]

MAD2-like 1 [Homo sapiens]

MAD2-like 1 [Homo sapiens]

MAD2 mitotic arrest deficient-like 1 (yeast) [synthetic construct]

MAD2-like 1 variant [Homo sapiens]

Chain A, The Mad2 Spindle Checkpoint Protein Possesses Two Distinct Natively Folded States

Chain A, The Mad2 Spindle Checkpoint Protein Undergoes Similar Major Conformational Changes Upon Binding To Either Mad1 Or Cdc20

Chain D, Crystal Structure Of Mad1-Mad2 Reveals A Conserved Mad2 Binding Motif In Mad1 And Cdc20.

PREDICTED: similar to Mitotic spindle assembly checkpoint protein MAD2A (MAD2-like 1) (HsMAD2) [Canis familiaris]

MAD2 (mitotic arrest deficient, homolog)-like 1 [Mus musculus]

PREDICTED: similar to Mitotic spindle assembly checkpoint protein MAD2A (MAD2-like 1) (HsMAD2) [Gallus gallus]

MGC81153 protein [Xenopus laevis]

Mad2l1-prov protein [Xenopus laevis]

Chain A, Solution Structure Of The Spindle Assembly Checkpoint Protein Human Mad2

PREDICTED: similar to spindle assembly checkpoint protein [Rattus norvegicus]

unnamed protein product [Tetraodon nigroviridis]

mitotic checkpoint component Mad2 [Mus musculus]

hypothetical protein AN2511.2 [Aspergillus nidulans FGSC A4]

unnamed protein product [Yarrowia lipolytica CLIB99]

Unknown (protein for MGC:112133) [Danio rerio]

rev7, putative [Trypanosoma brucei]

hypothetical protein UM04047.1 [Ustilago maydis 521]

MAD2 [Triticum aestivum]

MAD2 [Triticum aestivum]

MAD2 [Triticum aestivum]

cell cycle checkpoint protein MAD2 homolog [Zea mays]

OJ000223_09.14 [Oryza sativa (japonica cultivar-group)]

Hypothetical protein CBG13880 [Caenorhabditis briggsae]

Mad (yeast mitosis arrest deficient) related protein 2, isoform a [Caenorhabditis elegans]

putative mitotic spindle checkpoint protein [Oryza sativa (indica cultivar-group)]

PREDICTED: similar to Mitotic spindle assembly checkpoint protein MAD2A (MAD2-like 1) (HsMAD2) [Pan troglodytes]

mad2 [Schizosaccharomyces pombe]

hypothetical protein CNBC5740 [Cryptococcus neoformans var. neoformans B-3501A]

unnamed protein product [Debaryomyces hansenii CBS767]

unknown [Schistosoma japonicum]

At3g25980 [Arabidopsis thaliana]

GLP_127_6168_5557 [Giardia lamblia ATCC 50803]

ACR043Wp [Ashbya gossypii ATCC 10895]

unnamed protein product [Kluyveromyces lactis NRRL Y-1140]

hypothetical protein [Neurospora crassa]

CG17498-PA [Drosophila melanogaster]

GA14530-PA [Drosophila pseudoobscura]

MAD2 [Saccharomyces cerevisiae]

similar to CG17498-PA [Apis mellifera]

unnamed protein product [Candida glabrata CBS138]

hypothetical protein CaO19.8642 [Candida albicans SC5314]

hypothetical protein CaO19.1040 [Candida albicans SC5314]

ENSANGP00000017449 [Anopheles gambiae str. PEST]

hypothetical protein FG02639.1 [Gibberella zeae PH-1]

unnamed protein product [Mus musculus]

hypothetical protein MG08269.4 [Magnaporthe grisea 70-15]

PREDICTED: similar to Mitotic spindle assembly checkpoint protein MAD2A (MAD2-like 1) (HsMAD2) [Canis familiaris]

PREDICTED: similar to Mitotic spindle assembly checkpoint protein MAD2A (MAD2-like 1) (HsMAD2) [Canis familiaris]

Mad (yeast mitosis arrest deficient) related protein 2, isoform b [Caenorhabditis elegans]

GekBS188P [Gekko japonicus]

MAD2 mitotic arrest deficient-like 1 variant [Homo sapiens]

similar to MAD2 protein [Bos taurus]

hypothetical protein UM01742.1 [Ustilago maydis 521]

PREDICTED: similar to mitotic checkpoint component Mad2 [Canis familiaris]

Unknown (protein for MGC:110299) [Danio rerio]

unnamed protein product [Tetraodon nigroviridis]

Mad2l2-A protein [Xenopus laevis]

MAD2-like protein [Homo sapiens]

GA15539-PA [Drosophila pseudoobscura]

PREDICTED: similar to Mitotic spindle assembly checkpoint protein MAD2B (MAD2-like 2) (hREV7) [Pan troglodytes]
 
gb|AAO51442.1| similar to Homo sapiens (Human). MAD2-like protein 1 [Dictyostelium discoideum]
gb|EAL70818.1| hypothetical protein DDB0168106 [Dictyostelium discoideum]
gb|EAL70554.1| hypothetical protein DDB0217277 [Dictyostelium discoideum]
(203 aa)

Score: 174 bits (441), Expect: 1.95312e-42
Length: 203, Idn/Pos/Gap = 97/129/5 (47%/63%/2%)

Query:   1 MATAGSEQAPISLRGSTDTVIEFLRCAIYSILYQRGIYPPEMFRRASKFGTSVLVAQEAQ  60
           M  A + +  ISL+GST+ V EF   +I +IL+QRG+YPPE F R +K+G  +LV  +  
Sbjct:   1 MQAAVASKTNISLKGSTEIVTEFFSYSINTILFQRGLYPPESFTRVAKYGLPILVTNDQS  60

Query:  61 LDSYIERILQRHLRLWVLRGSVHRVVLAFAATADPGRILERWHFDLHMEQRATEDSSVPR 120
           L  Y++ +L + L  W+L G V ++VL          +LERW FD+  +     ++   +
Sbjct:  61 LKDYLDNVL-KQLSEWLLSGDVQKLVLVITDIVTK-EVLERWVFDVTTDIPKEGEAPRQK 118

Query: 121 DESVVMREIQAIIRQITASVTFLPLLDEPCSFDLLVYTDPALEADANEWEESDAKLITAP 180
            E  +M EIQAIIRQITASVTFLPLL   C+FDLLVYT   L A   +WEESD K IT  
Sbjct: 119 PEKEIMNEIQAIIRQITASVTFLPLLPNACTFDLLVYTSKDL-AVPQKWEESDPKFIT-- 175

Query: 181 RCEQVKLRSFTTNVHRVETGVAY 203
             +QVKLRSFTT +H+VE+ VAY
Sbjct: 176 NSQQVKLRSFTTTIHKVESMVAY 198



gb|AAH70283.1| MAD2-like 1 [Homo sapiens]
(205 aa)

Score: 169 bits (429), Expect: 4.35237e-41
Length: 205, Idn/Pos/Gap = 94/136/8 (45%/66%/3%)

Query:   1 MATAGSEQAPISLRGSTDTVIEFLRCAIYSILYQRGIYPPEMFRRASKFGTSVLVAQEAQ  60
           MA   S +  I+LRGS + V EF    I SILYQRGIYP E F R  K+G ++LV  + +
Sbjct:   1 MALQLSREQGITLRGSAEIVAEFFSFGINSILYQRGIYPSETFTRVQKYGLTLLVTTDLE  60

Query:  61 LDSYIERILQRHLRLWVLRGSVHRVVLAFAATADPGRILERWHFDLHMEQRATEDSSVPR 120
           L  Y+  ++++ L+ W+ + SV ++V+   +  + G +LERW FD+  ++ A +DS+ PR
Sbjct:  61 LIKYLNNVVEQ-LKDWLYKCSVQKLVVVI-SNIESGEVLERWQFDIECDKTAKDDSA-PR 117

Query: 121 DES--VVMREIQAIIRQITASVTFLPLLDEPCSFDLLVYTDPALEADANEWEESDAKLIT 178
           ++S   +  EI+++IRQITA+VTFLPLL+  CSFDLL+YTD  L     +WEES  + IT
Sbjct: 118 EKSQKAIQDEIRSVIRQITATVTFLPLLEVSCSFDLLIYTDKDLVV-PEKWEESGPQFIT 176

Query: 179 APRCEQVKLRSFTTNVHRVETGVAY 203
               E+V+LRSFTT VH+V + VAY
Sbjct: 177 --NSEEVRLRSFTTTVHKVNSMVAY 199



gb|AAH00356.1| MAD2-like 1 [Homo sapiens]
gb|AAH05945.1| MAD2-like 1 [Homo sapiens]
sp|Q13257|MD2L1_HUMAN Mitotic spindle assembly checkpoint protein MAD2A (MAD2-like 1) (HsMAD2)
gb|AAK38174.1| MAD2-like protein 1 [Homo sapiens]
gb|AAC52060.1| mitotic feedback control protein Madp2 homolog [Homo sapiens]
gb|AAC50781.1| Mad2
emb|CAA03943.1| MAD2 [Homo sapiens]
dbj|BAB63410.1| MAD2 [Homo sapiens]
ref|NP_002349.1| MAD2-like 1 [Homo sapiens]
(205 aa)

Score: 169 bits (428), Expect: 6.02626e-41
Length: 205, Idn/Pos/Gap = 93/136/8 (45%/66%/3%)

Query:   1 MATAGSEQAPISLRGSTDTVIEFLRCAIYSILYQRGIYPPEMFRRASKFGTSVLVAQEAQ  60
           MA   S +  I+LRGS + V EF    I SILYQRGIYP E F R  K+G ++LV  + +
Sbjct:   1 MALQLSREQGITLRGSAEIVAEFFSFGINSILYQRGIYPSETFTRVQKYGLTLLVTTDLE  60

Query:  61 LDSYIERILQRHLRLWVLRGSVHRVVLAFAATADPGRILERWHFDLHMEQRATEDSSVPR 120
           L  Y+  ++++ L+ W+ + SV ++V+   +  + G +LERW FD+  ++ A +DS+ PR
Sbjct:  61 LIKYLNNVVEQ-LKDWLYKCSVQKLVVVI-SNIESGEVLERWQFDIECDKTAKDDSA-PR 117

Query: 121 DES--VVMREIQAIIRQITASVTFLPLLDEPCSFDLLVYTDPALEADANEWEESDAKLIT 178
           ++S   +  EI+++IRQITA+VTFLPLL+  CSFDLL+YTD  L     +WEES  + IT
Sbjct: 118 EKSQKAIQDEIRSVIRQITATVTFLPLLEVSCSFDLLIYTDKDLVV-PEKWEESGPQFIT 176

Query: 179 APRCEQVKLRSFTTNVHRVETGVAY 203
               E+V+LRSFTT +H+V + VAY
Sbjct: 177 --NSEEVRLRSFTTTIHKVNSMVAY 199



gb|AAV38572.1| MAD2 mitotic arrest deficient-like 1 (yeast) [synthetic construct]
gb|AAX42727.1| MAD2 mitotic arrest deficient-like 1 [synthetic construct]
(206 aa)

Score: 169 bits (428), Expect: 6.12767e-41
Length: 205, Idn/Pos/Gap = 93/136/8 (45%/66%/3%)

Query:   1 MATAGSEQAPISLRGSTDTVIEFLRCAIYSILYQRGIYPPEMFRRASKFGTSVLVAQEAQ  60
           MA   S +  I+LRGS + V EF    I SILYQRGIYP E F R  K+G ++LV  + +
Sbjct:   1 MALQLSREQGITLRGSAEIVAEFFSFGINSILYQRGIYPSETFTRVQKYGLTLLVTTDLE  60

Query:  61 LDSYIERILQRHLRLWVLRGSVHRVVLAFAATADPGRILERWHFDLHMEQRATEDSSVPR 120
           L  Y+  ++++ L+ W+ + SV ++V+   +  + G +LERW FD+  ++ A +DS+ PR
Sbjct:  61 LIKYLNNVVEQ-LKDWLYKCSVQKLVVVI-SNIESGEVLERWQFDIECDKTAKDDSA-PR 117

Query: 121 DES--VVMREIQAIIRQITASVTFLPLLDEPCSFDLLVYTDPALEADANEWEESDAKLIT 178
           ++S   +  EI+++IRQITA+VTFLPLL+  CSFDLL+YTD  L     +WEES  + IT
Sbjct: 118 EKSQKAIQDEIRSVIRQITATVTFLPLLEVSCSFDLLIYTDKDLVV-PEKWEESGPQFIT 176

Query: 179 APRCEQVKLRSFTTNVHRVETGVAY 203
               E+V+LRSFTT +H+V + VAY
Sbjct: 177 --NSEEVRLRSFTTTIHKVNSMVAY 199



dbj|BAD97153.1| MAD2-like 1 variant [Homo sapiens]
(205 aa)

Score: 167 bits (423), Expect: 1.84339e-40
Length: 205, Idn/Pos/Gap = 92/135/8 (44%/65%/3%)

Query:   1 MATAGSEQAPISLRGSTDTVIEFLRCAIYSILYQRGIYPPEMFRRASKFGTSVLVAQEAQ  60
           MA   S +  I+LRG  + V EF    I SILYQRGIYP E F R  K+G ++LV  + +
Sbjct:   1 MALQLSREQGITLRGCAEIVAEFFSFGINSILYQRGIYPSETFTRVQKYGLTLLVTTDLE  60

Query:  61 LDSYIERILQRHLRLWVLRGSVHRVVLAFAATADPGRILERWHFDLHMEQRATEDSSVPR 120
           L  Y+  ++++ L+ W+ + SV ++V+   +  + G +LERW FD+  ++ A +DS+ PR
Sbjct:  61 LIKYLNNVVEQ-LKDWLYKCSVQKLVVVI-SNIESGEVLERWQFDIECDKTAKDDSA-PR 117

Query: 121 DES--VVMREIQAIIRQITASVTFLPLLDEPCSFDLLVYTDPALEADANEWEESDAKLIT 178
           ++S   +  EI+++IRQITA+VTFLPLL+  CSFDLL+YTD  L     +WEES  + IT
Sbjct: 118 EKSQKAIQDEIRSVIRQITATVTFLPLLEVSCSFDLLIYTDKDLVV-PEKWEESGPQFIT 176

Query: 179 APRCEQVKLRSFTTNVHRVETGVAY 203
               E+V+LRSFTT +H+V + VAY
Sbjct: 177 --NSEEVRLRSFTTTIHKVNSMVAY 199



pdb|1S2H|A Chain A, The Mad2 Spindle Checkpoint Protein Possesses Two Distinct Natively Folded States
(206 aa)

Score: 167 bits (422), Expect: 2.61703e-40
Length: 205, Idn/Pos/Gap = 92/135/8 (44%/65%/3%)

Query:   1 MATAGSEQAPISLRGSTDTVIEFLRCAIYSILYQRGIYPPEMFRRASKFGTSVLVAQEAQ  60
           MA   S +  I+LRGS + V EF    I SILYQRGIYP E F R  K+G ++LV  + +
Sbjct:   2 MALQLSREQGITLRGSAEIVAEFFSFGINSILYQRGIYPSETFTRVQKYGLTLLVTTDLE  61

Query:  61 LDSYIERILQRHLRLWVLRGSVHRVVLAFAATADPGRILERWHFDLHMEQRATEDSSVPR 120
           L  Y+  ++++ L+ W+ + SV ++V+   +  + G +LERW FD+  ++ A +DS+ PR
Sbjct:  62 LIKYLNNVVEQ-LKDWLYKCSVQKLVVVI-SNIESGEVLERWQFDIECDKTAKDDSA-PR 118

Query: 121 DES--VVMREIQAIIRQITASVTFLPLLDEPCSFDLLVYTDPALEADANEWEESDAKLIT 178
           ++S   +  EI+++I QITA+VTFLPLL+  CSFDLL+YTD  L     +WEES  + IT
Sbjct: 119 EKSQKAIQDEIRSVIAQITATVTFLPLLEVSCSFDLLIYTDKDLVV-PEKWEESGPQFIT 177

Query: 179 APRCEQVKLRSFTTNVHRVETGVAY 203
               E+V+LRSFTT +H+V + VAY
Sbjct: 178 --NSEEVRLRSFTTTIHKVNSMVAY 200



pdb|1KLQ|A Chain A, The Mad2 Spindle Checkpoint Protein Undergoes Similar Major Conformational Changes Upon Binding To Either Mad1 Or Cdc20
(197 aa)

Score: 166 bits (421), Expect: 3.19725e-40
Length: 195, Idn/Pos/Gap = 90/132/8 (46%/67%/4%)

Query:  11 ISLRGSTDTVIEFLRCAIYSILYQRGIYPPEMFRRASKFGTSVLVAQEAQLDSYIERILQ  70
           I+LRGS + V EF    I SILYQRGIYP E F R  K+G ++LV  + +L  Y+  +++
Sbjct:   3 ITLRGSAEIVAEFFSFGINSILYQRGIYPSETFTRVQKYGLTLLVTTDLELIKYLNNVVE  62

Query:  71 RHLRLWVLRGSVHRVVLAFAATADPGRILERWHFDLHMEQRATEDSSVPRDES--VVMRE 128
           + L+ W+ + SV ++V+   +  + G +LERW FD+  ++ A +DS+ PR++S   +  E
Sbjct:  63 Q-LKDWLYKCSVQKLVVVI-SNIESGEVLERWQFDIECDKTAKDDSA-PREKSQKAIQDE 119

Query: 129 IQAIIRQITASVTFLPLLDEPCSFDLLVYTDPALEADANEWEESDAKLITAPRCEQVKLR 188
           I+++IRQITA+VTFLPLL+  CSFDLL+YTD  L     +WEES  + IT    E+V+LR
Sbjct: 120 IRSVIRQITATVTFLPLLEVSCSFDLLIYTDKDLVV-PEKWEESGPQFIT--NSEEVRLR 176

Query: 189 SFTTNVHRVETGVAY 203
           SFTT +H+V + VAY
Sbjct: 177 SFTTTIHKVNSMVAY 191



pdb|1GO4|D Chain D, Crystal Structure Of Mad1-Mad2 Reveals A Conserved Mad2 Binding Motif In Mad1 And Cdc20.
pdb|1GO4|C Chain C, Crystal Structure Of Mad1-Mad2 Reveals A Conserved Mad2 Binding Motif In Mad1 And Cdc20.
pdb|1GO4|B Chain B, Crystal Structure Of Mad1-Mad2 Reveals A Conserved Mad2 Binding Motif In Mad1 And Cdc20.
pdb|1GO4|A Chain A, Crystal Structure Of Mad1-Mad2 Reveals A Conserved Mad2 Binding Motif In Mad1 And Cdc20.
(205 aa)

Score: 166 bits (421), Expect: 3.62353e-40
Length: 205, Idn/Pos/Gap = 92/135/8 (44%/65%/3%)

Query:   1 MATAGSEQAPISLRGSTDTVIEFLRCAIYSILYQRGIYPPEMFRRASKFGTSVLVAQEAQ  60
           MA   S +  I+LRGS + V EF    I SILYQRGIYP E F R  K+G ++LV  + +
Sbjct:   1 MALQLSREQGITLRGSAEIVAEFFSFGINSILYQRGIYPSETFTRVQKYGLTLLVTTDLE  60

Query:  61 LDSYIERILQRHLRLWVLRGSVHRVVLAFAATADPGRILERWHFDLHMEQRATEDSSVPR 120
           L  Y+  ++++ L+ W+ + SV ++V+   +  + G +LERW FD+  ++ A +DS+ PR
Sbjct:  61 LIKYLNNVVEQ-LKDWLYKCSVQKLVVVI-SNIESGEVLERWQFDIECDKTAKDDSA-PR 117

Query: 121 DES--VVMREIQAIIRQITASVTFLPLLDEPCSFDLLVYTDPALEADANEWEESDAKLIT 178
           ++S   +  EI+++I QITA+VTFLPLL+  CSFDLL+YTD  L     +WEES  + IT
Sbjct: 118 EKSQKAIQDEIRSVIAQITATVTFLPLLEVSCSFDLLIYTDKDLVV-PEKWEESGPQFIT 176

Query: 179 APRCEQVKLRSFTTNVHRVETGVAY 203
               E+V+LRSFTT +H+V + VAY
Sbjct: 177 --NSEEVRLRSFTTTIHKVNSMVAY 199



ref|XP_533278.1| PREDICTED: similar to Mitotic spindle assembly checkpoint protein MAD2A (MAD2-like 1) (HsMAD2) [Canis familiaris]
(333 aa)

Score: 166 bits (421), Expect: 3.90611e-40
Length: 205, Idn/Pos/Gap = 92/136/8 (44%/66%/3%)

Query:   1 MATAGSEQAPISLRGSTDTVIEFLRCAIYSILYQRGIYPPEMFRRASKFGTSVLVAQEAQ  60
           MA   S +  I+LRGS + V EF    I SILYQRGIYP E F R  K+G ++LV  + +
Sbjct: 130 MALQLSREQGITLRGSAEIVAEFFSFGINSILYQRGIYPSETFTRVQKYGLTLLVTTDPE 189

Query:  61 LDSYIERILQRHLRLWVLRGSVHRVVLAFAATADPGRILERWHFDLHMEQRATEDSSVPR 120
           L  Y+  ++++ L+ W+ + SV ++V+   +  + G +LERW FD+  ++ A +D++ PR
Sbjct: 190 LMKYLNNVVEQ-LKDWLYKCSVQKLVVVI-SNIESGEVLERWQFDIECDKTAKDDNT-PR 246

Query: 121 DES--VVMREIQAIIRQITASVTFLPLLDEPCSFDLLVYTDPALEADANEWEESDAKLIT 178
           ++S   +  EI+++IRQITA+VTFLPLL+  CSFDLL+YTD  L     +WEES  + IT
Sbjct: 247 EKSQKAIQDEIRSVIRQITATVTFLPLLEVSCSFDLLIYTDKDLVV-PEKWEESGPQFIT 305

Query: 179 APRCEQVKLRSFTTNVHRVETGVAY 203
               E+V+LRSFTT +H+V + VAY
Sbjct: 306 --NSEEVRLRSFTTTIHKVNSMVAY 328



ref|NP_062372.2| MAD2 (mitotic arrest deficient, homolog)-like 1 [Mus musculus]
gb|AAF69525.1| spindle assembly checkpoint protein [Mus musculus]
sp|Q9Z1B5|MD2L1_MOUSE Mitotic spindle assembly checkpoint protein MAD2A (MAD2-like 1)
dbj|BAC38700.1| unnamed protein product [Mus musculus]
dbj|BAB28338.1| unnamed protein product [Mus musculus]
gb|AAH89012.1| MAD2 (mitotic arrest deficient, homolog)-like 1 [Mus musculus]
(205 aa)

Score: 165 bits (418), Expect: 8.27698e-40
Length: 205, Idn/Pos/Gap = 91/134/8 (44%/65%/3%)

Query:   1 MATAGSEQAPISLRGSTDTVIEFLRCAIYSILYQRGIYPPEMFRRASKFGTSVLVAQEAQ  60
           MA   + +  I+LRGS + V EF    I SILYQRGIYP E F R  K+G ++L   + +
Sbjct:   1 MAQQLAREQGITLRGSAEIVAEFFSFGINSILYQRGIYPSETFTRVQKYGLTLLTTTDPE  60

Query:  61 LDSYIERILQRHLRLWVLRGSVHRVVLAFAATADPGRILERWHFDLHMEQRATEDSSVPR 120
           L  Y+  ++++ L+ W+ + SV ++V+   +  + G +LERW FD+  ++ A E+  V R
Sbjct:  61 LIKYLNNVVEQ-LKEWLYKCSVQKLVVVI-SNIESGEVLERWQFDIECDKTAKEE-GVRR 117

Query: 121 DES--VVMREIQAIIRQITASVTFLPLLDEPCSFDLLVYTDPALEADANEWEESDAKLIT 178
           ++S   +  EI+++IRQITA+VTFLPLL+  CSFDLL+YTD  L     +WEES  + IT
Sbjct: 118 EKSQKAIQDEIRSVIRQITATVTFLPLLEVSCSFDLLIYTDKDLVV-PEKWEESGPQFIT 176

Query: 179 APRCEQVKLRSFTTNVHRVETGVAY 203
              CE+V+LRSFTT +H+V + VAY
Sbjct: 177 --NCEEVRLRSFTTTIHKVNSMVAY 199



ref|XP_420629.1| PREDICTED: similar to Mitotic spindle assembly checkpoint protein MAD2A (MAD2-like 1) (HsMAD2) [Gallus gallus]
(206 aa)

Score: 165 bits (418), Expect: 8.48678e-40
Length: 204, Idn/Pos/Gap = 89/135/8 (43%/66%/3%)

Query:   2 ATAGSEQAPISLRGSTDTVIEFLRCAIYSILYQRGIYPPEMFRRASKFGTSVLVAQEAQL  61
           A    EQ  I+LRGS + V EF    I SILYQRGIYPPE F R  K+G ++LV  + +L
Sbjct:   3 AQLSREQQGITLRGSAEIVAEFFSYGINSILYQRGIYPPETFTRVQKYGLTLLVTTDPEL  62

Query:  62 DSYIERILQRHLRLWVLRGSVHRVVLAFAATADPGRILERWHFDLHMEQRATEDSSVPRD 121
            +Y+  ++++ ++ W+ + +V R+V+  ++  +   +LERW FD+  ++ A  +S+ PR+
Sbjct:  63 KNYLNNVVEQ-MKEWLYKCTVQRLVVVISSIEN-NEVLERWQFDIECDKNARGESA-PRE 119

Query: 122 ES--VVMREIQAIIRQITASVTFLPLLDEPCSFDLLVYTDPALEADANEWEESDAKLITA 179
           +S   +  EI+++IRQITA+VTFLPLL+  C+FDLL+YTD  L     +WEES  + I  
Sbjct: 120 KSQKAIQDEIRSVIRQITATVTFLPLLETACAFDLLIYTDKDLVV-PEKWEESGPQFIA- 177

Query: 180 PRCEQVKLRSFTTNVHRVETGVAY 203
              E+V+LRSFTT +H+V + VAY
Sbjct: 178 -NSEEVRLRSFTTTIHKVNSMVAY 200



gb|AAH68714.1| MGC81153 protein [Xenopus laevis]
(203 aa)

Score: 164 bits (416), Expect: 1.52194e-39
Length: 193, Idn/Pos/Gap = 83/125/5 (43%/64%/2%)

Query:  11 ISLRGSTDTVIEFLRCAIYSILYQRGIYPPEMFRRASKFGTSVLVAQEAQLDSYIERILQ  70
           I+L+GS + V EF  C I SILYQRGIYP E F R  K+G ++LV+ +  L  Y+ ++  
Sbjct:  10 ITLKGSAEIVSEFFYCGINSILYQRGIYPSETFTRVQKYGLTLLVSTDPALKEYLNKVTD  69

Query:  71 RHLRLWVLRGSVHRVVLAFAATADPGRILERWHFDLHMEQRATEDSSVPRDESVVMREIQ 130
           + L+ W+ +  V ++V+   +  D   ILERW FD+  ++   +     + + V+  EI+
Sbjct:  70 Q-LKEWLYKCQVQKLVVVITSI-DSSEILERWQFDIECDKTVKDGIVREKSQKVIQEEIR 127

Query: 131 AIIRQITASVTFLPLLDEPCSFDLLVYTDPALEADANEWEESDAKLITAPRCEQVKLRSF 190
           ++IRQITA+VTFLPLL+  C+FDLL+YTD  LE    +WEES  + ++    E+V+LRSF
Sbjct: 128 SVIRQITATVTFLPLLETACAFDLLIYTDKDLEV-PEKWEESGPQFVS--NSEEVRLRSF 184

Query: 191 TTNVHRVETGVAY 203
           TT +H+V + VAY
Sbjct: 185 TTTIHKVNSMVAY 197



gb|AAH45227.1| Mad2l1-prov protein [Xenopus laevis]
gb|AAB41527.1| spindle assembly checkpoint component
(203 aa)

Score: 164 bits (415), Expect: 1.9065e-39
Length: 193, Idn/Pos/Gap = 83/125/5 (43%/64%/2%)

Query:  11 ISLRGSTDTVIEFLRCAIYSILYQRGIYPPEMFRRASKFGTSVLVAQEAQLDSYIERILQ  70
           I+L+GS + V EF  C I SILYQRGIYP E F R  K+G ++LV+ +  L  Y+ ++  
Sbjct:  10 ITLKGSAEIVSEFFFCGINSILYQRGIYPSETFTRIQKYGLTLLVSTDPALKEYLNKVTD  69

Query:  71 RHLRLWVLRGSVHRVVLAFAATADPGRILERWHFDLHMEQRATEDSSVPRDESVVMREIQ 130
           + L+ W+ +  V ++V+   +  D   ILERW FD+  ++   +     + + V+  EI+
Sbjct:  70 Q-LKDWLYKCQVQKLVVVITSI-DSNEILERWQFDIECDKTVKDGIVREKSQKVIQEEIR 127

Query: 131 AIIRQITASVTFLPLLDEPCSFDLLVYTDPALEADANEWEESDAKLITAPRCEQVKLRSF 190
           ++IRQITA+VTFLPLL+  C+FDLL+YTD  LE    +WEES  + ++    E+V+LRSF
Sbjct: 128 SVIRQITATVTFLPLLETACAFDLLIYTDKDLEV-PEKWEESGPQFVS--NSEEVRLRSF 184

Query: 191 TTNVHRVETGVAY 203
           TT +H+V + VAY
Sbjct: 185 TTTIHKVNSMVAY 197



pdb|1DUJ|A Chain A, Solution Structure Of The Spindle Assembly Checkpoint Protein Human Mad2
(187 aa)

Score: 162 bits (409), Expect: 8.00762e-39
Length: 191, Idn/Pos/Gap = 87/129/8 (45%/67%/4%)

Query:  11 ISLRGSTDTVIEFLRCAIYSILYQRGIYPPEMFRRASKFGTSVLVAQEAQLDSYIERILQ  70
           I+LRGS + V EF    I SILYQRGIYP E F R  K+G ++LV  + +L  Y+  +++
Sbjct:   3 ITLRGSAEIVAEFFSFGINSILYQRGIYPSETFTRVQKYGLTLLVTTDLELIKYLNNVVE  62

Query:  71 RHLRLWVLRGSVHRVVLAFAATADPGRILERWHFDLHMEQRATEDSSVPRDES--VVMRE 128
           + L+ W+ + SV ++V+   +  + G +LERW FD+  ++ A +DS+ PR++S   +  E
Sbjct:  63 Q-LKDWLYKCSVQKLVVVI-SNIESGEVLERWQFDIECDKTAKDDSA-PREKSQKAIQDE 119

Query: 129 IQAIIRQITASVTFLPLLDEPCSFDLLVYTDPALEADANEWEESDAKLITAPRCEQVKLR 188
           I+++IRQITA+VTFLPLL+  CSFDLL+YTD  L     +WEES  + IT    E+V+LR
Sbjct: 120 IRSVIRQITATVTFLPLLEVSCSFDLLIYTDKDLVV-PEKWEESGPQFIT--NSEEVRLR 176

Query: 189 SFTTNVHRVET 199
           SFTT +H+V +
Sbjct: 177 SFTTTIHKVNS 187



ref|XP_216161.1| PREDICTED: similar to spindle assembly checkpoint protein [Rattus norvegicus]
(205 aa)

Score: 162 bits (409), Expect: 8.34875e-39
Length: 205, Idn/Pos/Gap = 91/133/8 (44%/64%/3%)

Query:   1 MATAGSEQAPISLRGSTDTVIEFLRCAIYSILYQRGIYPPEMFRRASKFGTSVLVAQEAQ  60
           MA   +    I+LRGS + V EF    I SILYQRGIYP E F R  K+G ++LV  + +
Sbjct:   1 MAQQLARDQGITLRGSAEIVAEFFSFGINSILYQRGIYPSETFTRVQKYGLTLLVTTDPE  60

Query:  61 LDSYIERILQRHLRLWVLRGSVHRVVLAFAATADPGRILERWHFDLHMEQRATEDSSVPR 120
           L  Y+  ++++ L+ W+ + SV ++V+   +  + G +LERW FD+  ++ A E+  V R
Sbjct:  61 LIKYLNNVVEQ-LKEWLYKCSVQKLVVVI-SNIESGEVLERWQFDIECDKTAKEE-GVRR 117

Query: 121 DES--VVMREIQAIIRQITASVTFLPLLDEPCSFDLLVYTDPALEADANEWEESDAKLIT 178
           ++S   +  EI+++IRQITA+VTFLPLL+  CSFDLL+YTD  L     +WEES  + IT
Sbjct: 118 EKSQKAIQDEIRSVIRQITATVTFLPLLEVSCSFDLLIYTDKDLVV-PEKWEESGPQFIT 176

Query: 179 APRCEQVKLRSFTTNVHRVETGVAY 203
               E+V+LRSFTT +H+V + VAY
Sbjct: 177 --NSEEVRLRSFTTTIHKVNSMVAY 199



emb|CAF95367.1| unnamed protein product [Tetraodon nigroviridis]
(197 aa)

Score: 160 bits (405), Expect: 2.34938e-38
Length: 200, Idn/Pos/Gap = 90/134/8 (45%/67%/4%)

Query:   6 SEQAPISLRGSTDTVIEFLRCAIYSILYQRGIYPPEMFRRASKFGTSVLVAQEAQLDSYI  65
           S Q  I+LRGS + V +F    I SILYQRGIYPPE F R + +  S+ +  + QL +Y+
Sbjct:   3 STQKGITLRGSAELVADFFSFGISSILYQRGIYPPETFTRVTHYDMSLQLTSDPQLKNYL  62

Query:  66 ERILQRHLRLWVLRGSVHRVVLAFAATADPGRILERWHFDLHMEQRATEDSSVPRDESV- 124
             ++ + L+ W+L  +V ++VL      +  ++LERW FD+  ++ A E SS PR++S+ 
Sbjct:  63 TDVVSQ-LKEWLLECTVQKLVLVITCL-ETSQVLERWQFDIECDKSAKE-SSAPREKSIK 119

Query: 125 -VMREIQAIIRQITASVTFLPLLDEPCSFDLLVYTDPALEADANEWEESDAKLITAPRCE 183
            +  EI+++IRQITA+VTFLPLL+ PC+FDLLVYTD  L     +W ES  ++I   + E
Sbjct: 120 TIQDEIRSVIRQITATVTFLPLLETPCAFDLLVYTDKDLVV-PEKWVESGPQIID--QSE 176

Query: 184 QVKLRSFTTNVHRVETGVAY 203
           +V+LRSFTT++H+V + VAY
Sbjct: 177 EVRLRSFTTSIHKVNSMVAY 196



gb|AAD09238.1| mitotic checkpoint component Mad2 [Mus musculus]
(205 aa)

Score: 159 bits (403), Expect: 4.39265e-38
Length: 205, Idn/Pos/Gap = 89/132/8 (43%/64%/3%)

Query:   1 MATAGSEQAPISLRGSTDTVIEFLRCAIYSILYQRGIYPPEMFRRASKFGTSVLVAQEAQ  60
           MA   + +  I+LRGS + V EF    I SILYQRGIYP E F R  K+G ++L   + +
Sbjct:   1 MAQQLAREQGITLRGSAEIVAEFFSFGINSILYQRGIYPSETFTRVQKYGLTLLTTTDPE  60

Query:  61 LDSYIERILQRHLRLWVLRGSVHRVVLAFAATADPGRILERWHFDLHMEQRATEDSSVPR 120
           L  Y+  ++++ L+ W+ + SV ++V+   +  + G +LERW FD+  ++ A E+  V R
Sbjct:  61 LIKYLNNVVEQ-LKEWLYKCSVQKLVVVI-SNIESGEVLERWQFDIECDKTAKEE-GVRR 117

Query: 121 DES--VVMREIQAIIRQITASVTFLPLLDEPCSFDLLVYTDPALEADANEWEESDAKLIT 178
           ++S   +  EI+++IRQITA+VTFLPLL+  CSFDLL+Y D  L     +WEES  + IT
Sbjct: 118 EKSQKAIQDEIRSVIRQITATVTFLPLLEVSCSFDLLIYADKDLVV-PEKWEESGPQFIT 176

Query: 179 APRCEQVKLRSFTTNVHRVETGVAY 203
               E+V+LRSFTT +H+V + VAY
Sbjct: 177 --NSEEVRLRSFTTTIHKVNSMVAY 199



gb|EAA63996.1| hypothetical protein AN2511.2 [Aspergillus nidulans FGSC A4]
ref|XP_406648.1| hypothetical protein AN2511.2 [Aspergillus nidulans FGSC A4]
(225 aa)

Score: 157 bits (397), Expect: 2.03928e-37
Length: 215, Idn/Pos/Gap = 90/133/30 (41%/61%/13%)

Query:  11 ISLRGSTDTVIEFLRCAIYSILYQRGIYPPEMFRRASKFGTSVLVAQEAQLDSYIERILQ  70
           +S++GS+  V EF   +I SIL+QRG+YPPE F    K+G ++LV  + Q+ +YI++I+ 
Sbjct:  15 LSIKGSSKLVAEFFEYSINSILFQRGVYPPEDFTTVKKYGLNMLVTADDQVKAYIKKIMS  74

Query:  71 RHLRLWVLRGSVHRVVLAFAATADPGRILERWHFDLHM----EQRATEDS---------- 116
           + L  W+L G + ++V+      + G  +ERW FD+ +    + ++T  S          
Sbjct:  75 Q-LNKWMLGGKISKLVVVI-TDKETGEHVERWQFDVQIFGKQKSQSTRKSGDKENDTPGD 132

Query: 117 -----SVPRDESVVMREIQAIIRQITASVTFLPLLDEPCSFDLLVYTDPALEADAN---E 168
                +V + E  +  EIQAI RQITASVTFLP+LD  C+F++LVY D    AD++   E
Sbjct: 133 VGQPETVEKTEKQIQEEIQAIFRQITASVTFLPVLDGDCTFNVLVYAD----ADSDVPVE 188

Query: 169 WEESDAKLITAPRCEQVKLRSFTTNVHRVETGVAY 203
           W +SDAK I  P  E+V+LRSF+TN HRVET V+Y
Sbjct: 189 WGDSDAKDIKNP--EKVQLRSFSTNNHRVETMVSY 221



emb|CAG79505.1| unnamed protein product [Yarrowia lipolytica CLIB99]
ref|XP_503912.1| hypothetical protein [Yarrowia lipolytica]
(210 aa)

Score: 157 bits (396), Expect: 2.82358e-37
Length: 205, Idn/Pos/Gap = 84/136/20 (40%/66%/9%)

Query:  11 ISLRGSTDTVIEFLRCAIYSILYQRGIYPPEMFRRASKFGTSVLVAQEAQLDSYIERILQ  70
           +S+RGS+ TV EF   +I +ILYQRGIYP + F++  K+G +VLV  ++++ +YI +I+ 
Sbjct:  10 LSIRGSSKTVAEFFEYSINTILYQRGIYPADDFQQVKKYGINVLVTVDSEVKAYIRKIMG  69

Query:  71 RHLRLWVLRGSVHRVVLAFAATADPGRILERWHFDLHMEQRATEDSSVPRD--------- 121
           + L  W++ G + ++++A   + + G ++ERW FD+H+  + T+ +S   D         
Sbjct:  70 Q-LHKWLVGGKIQKLIVAI-TSKESGEVVERWQFDIHISGKDTDTASKETDTKTNGDKKS 127

Query: 122 ESVVMREIQAIIRQITASVTFLPLLDEPCSFDLLVYTDPALEADA---NEWEESDAKLIT 178
           +  + +EIQAI+RQITASV+FLP+L++ C+F++LVY     E DA    EW +S  + I 
Sbjct: 128 DDQIQQEIQAIMRQITASVSFLPVLEDECTFNVLVYA----EQDAPVPPEWADSANREIK 183

Query: 179 APRCEQVKLRSFTTNVHRVETGVAY 203
            P  EQV+LRSF+TN H+++T VAY
Sbjct: 184 NP--EQVQLRSFSTNEHKIDTLVAY 206



gb|AAH93212.1| Unknown (protein for MGC:112133) [Danio rerio]
ref|NP_001017739.1| hypothetical protein LOC550434 [Danio rerio]
(202 aa)

Score: 155 bits (393), Expect: 6.83764e-37
Length: 195, Idn/Pos/Gap = 84/130/8 (43%/66%/4%)

Query:  11 ISLRGSTDTVIEFLRCAIYSILYQRGIYPPEMFRRASKFGTSVLVAQEAQLDSYIERILQ  70
           I+L+GS + V EF    I SILYQRGIYP E F R +++  S+ +  + +L +Y+  ++ 
Sbjct:   8 ITLKGSAELVAEFFSFGINSILYQRGIYPAETFTRVTQYDMSLQLTTDTKLKNYLTNVIS  67

Query:  71 RHLRLWVLRGSVHRVVLAFAATADPGRILERWHFDLHMEQRATEDSSVPRDESV--VMRE 128
           + L+ W+   +V ++V+      +   +LERW FD+  ++ A E SS PR++S+  +  E
Sbjct:  68 Q-LKEWLFECTVQKLVVVITCL-ETNEVLERWQFDIQCDKTAKE-SSAPREKSIKAIQEE 124

Query: 129 IQAIIRQITASVTFLPLLDEPCSFDLLVYTDPALEADANEWEESDAKLITAPRCEQVKLR 188
           I+++IRQITA+VTFLPLL+  C+ DLL+YTD  LE    +WEES  +LI   + E+V+LR
Sbjct: 125 IRSVIRQITATVTFLPLLETACALDLLIYTDKDLEV-PEQWEESGPQLID--QSEEVRLR 181

Query: 189 SFTTNVHRVETGVAY 203
           SFTT++H+V + VAY
Sbjct: 182 SFTTSIHKVNSMVAY 196



gb|AAX80262.1| rev7, putative [Trypanosoma brucei]
(201 aa)

Score: 154 bits (390), Expect: 1.44889e-36
Length: 193, Idn/Pos/Gap = 75/120/3 (38%/62%/1%)

Query:  11 ISLRGSTDTVIEFLRCAIYSILYQRGIYPPEMFRRASKFGTSVLVAQEAQLDSYIERILQ  70
           I+ R S  T+ EFL  AIY +LYQRG+YP + F++ +++G  ++V+ + +L+SY+  +LQ
Sbjct:   8 ITFRSSVSTITEFLGFAIYCVLYQRGVYPSDSFQQVTRYGVQLMVSVDEELNSYLAEVLQ  67

Query:  71 RHLRLWVLRGSVHRVVLAFAATADPGRILERWHFDLHMEQRATEDSSVPRDESVVMREIQ 130
           + ++ WV +  + ++VL        G ++ERW FD+  +     +    + +  + +EIQ
Sbjct:  68 QVIK-WVSQDKLRKLVLVLVDAETKGDVVERWVFDIATQGLEAVEGVNSKSDDTLRKEIQ 126

Query: 131 AIIRQITASVTFLPLLDEPCSFDLLVYTDPALEADANEWEESDAKLITAPRCEQVKLRSF 190
           A++RQ+T+SV++LPLL  PC FD+LVY DP  E     WE SD +LI      +V LRSF
Sbjct: 127 AVLRQVTSSVSYLPLLHRPCYFDMLVYADPDTELPTGSWELSDPRLIMGS--SEVTLRSF 184

Query: 191 TTNVHRVETGVAY 203
           +T+ H V   VAY
Sbjct: 185 STSFHSVSASVAY 197



gb|EAK84972.1| hypothetical protein UM04047.1 [Ustilago maydis 521]
ref|XP_401662.1| hypothetical protein UM04047.1 [Ustilago maydis 521]
(217 aa)

Score: 154 bits (389), Expect: 1.71201e-36
Length: 200, Idn/Pos/Gap = 88/126/10 (44%/63%/5%)

Query:  11 ISLRGSTDTVIEFLRCAIYSILYQRGIYPPEMFRRASKFGTSVLVAQEAQLDSYIERILQ  70
           ++L+GST  V EF   ++ SILYQRGIYP + F+   K+G  +L   +  L  Y++  + 
Sbjct:  14 LTLKGSTALVHEFFNYSVQSILYQRGIYPSDDFKTVKKYGLQMLTTTDDGLIEYLDTAMA  73

Query:  71 RHLRLWVLRGSVHRVVLAFAATADPGRILERWHFDLHMEQRATEDSSVP-------RDES 123
           + L+ W+ RG V R+V+      D G   ERW FD+ +     ++SS P       + ++
Sbjct:  74 Q-LKTWLERGDVTRLVVVIIEK-DSGETRERWQFDVDVINTPLDESSTPASTEKPKKTDA 131

Query: 124 VVMREIQAIIRQITASVTFLPLLDEPCSFDLLVYTDPALEADANEWEESDAKLITAPRCE 183
            V  EI AII+QITAS TFLP+LDEPC+F +L YT+   +A A EW +SDA+LI   + E
Sbjct: 132 QVRAEIAAIIKQITASCTFLPVLDEPCAFQILAYTNKDAQAPA-EWIDSDARLIAEGQAE 190

Query: 184 QVKLRSFTTNVHRVETGVAY 203
           QV+LRSF+T+VHRV+  VAY
Sbjct: 191 QVRLRSFSTHVHRVDAMVAY 210



dbj|BAD90975.1| MAD2 [Triticum aestivum]
(207 aa)

Score: 153 bits (387), Expect: 2.89599e-36
Length: 211, Idn/Pos/Gap = 84/125/6 (39%/59%/2%)

Query:   1 MATAGSEQAPISLRGSTDTVIEFLRCAIYSILYQRGIYPPEMFRRASKFGTSVLVAQEAQ  60
           MA+  + +  I+L+GS   V EF   A  SILY RG+YP E F +  K+G  +L+ Q+  
Sbjct:   1 MASRMASKDIITLKGSAAIVSEFFGYAANSILYNRGVYPEESFGKVKKYGLPMLLTQDEA  60

Query:  61 LDSYIERILQRHLRLWVLRGSVHRVVLAFAATADPGRILERWHFDLHMEQRATEDSSVP- 119
           + +++   L   L  W+  G + R+VL   + A  G +LERW+F++  +    E  +V  
Sbjct:  61 VKTFLTN-LTSQLSEWLEGGKLQRIVLVIMSKAT-GEVLERWNFNIITDGEVVEKGAVKE 118

Query: 120 RDESVVMREIQAIIRQITASVTFLPLLDEPCSFDLLVYTDPALEADANEWEESDAKLITA 179
           + +  +MREIQAI+RQ+ + ++FLP LDEPC FD+L YTD         W ESDAKLI  
Sbjct: 119 KSDKEIMREIQAIMRQVNSCISFLPCLDEPCIFDVLAYTDSDTTVPFT-WMESDAKLIDN 177

Query: 180 PRCEQVKLRSFTTNVHRVETGVAYACKELTD 210
           P  + VKL SF T +H+V+T V+Y   +L +
Sbjct: 178 P--QMVKLHSFDTKIHKVDTLVSYKVDDLDE 206



dbj|BAD90976.1| MAD2 [Triticum aestivum]
(207 aa)

Score: 153 bits (387), Expect: 3.04466e-36
Length: 211, Idn/Pos/Gap = 84/125/6 (39%/59%/2%)

Query:   1 MATAGSEQAPISLRGSTDTVIEFLRCAIYSILYQRGIYPPEMFRRASKFGTSVLVAQEAQ  60
           MA+  + +  I+L+GS   V EF   A  SILY RG+YP E F +  K+G  +L+ Q+  
Sbjct:   1 MASRTASKDIITLKGSAAIVSEFFGYAANSILYNRGVYPEESFGKVKKYGLPMLLTQDEA  60

Query:  61 LDSYIERILQRHLRLWVLRGSVHRVVLAFAATADPGRILERWHFDLHMEQRATEDSSVP- 119
           + +++   L   L  W+  G + R+VL   + A  G +LERW+F++  +    E  +V  
Sbjct:  61 VKTFLTN-LTSQLSEWLEGGKLQRIVLVIMSKAT-GEVLERWNFNIITDGEVVEKGAVKE 118

Query: 120 RDESVVMREIQAIIRQITASVTFLPLLDEPCSFDLLVYTDPALEADANEWEESDAKLITA 179
           + +  +MREIQAI+RQ+ + ++FLP LDEPC FD+L YTD         W ESDAKLI  
Sbjct: 119 KSDKEIMREIQAIMRQVNSCISFLPCLDEPCIFDVLAYTDSDTTVPFT-WMESDAKLIEN 177

Query: 180 PRCEQVKLRSFTTNVHRVETGVAYACKELTD 210
           P  + VKL SF T +H+V+T V+Y   +L +
Sbjct: 178 P--QMVKLHSFDTKIHKVDTLVSYKVDDLDE 206



dbj|BAD90977.1| MAD2 [Triticum aestivum]
(207 aa)

Score: 153 bits (386), Expect: 3.62773e-36
Length: 211, Idn/Pos/Gap = 83/124/6 (39%/58%/2%)

Query:   1 MATAGSEQAPISLRGSTDTVIEFLRCAIYSILYQRGIYPPEMFRRASKFGTSVLVAQEAQ  60
           MA+  + +  I+L+GS   V EF   A  SILY RG+YP E F +  K+G  +L+ Q+  
Sbjct:   1 MASRTASKDIITLKGSAAIVSEFFGYAANSILYNRGVYPEESFGKVKKYGLPMLLTQDKA  60

Query:  61 LDSYIERILQRHLRLWVLRGSVHRVVLAFAATADPGRILERWHFDLHMEQRATEDSSVP- 119
           + +++   L   L  W+  G + R+VL   +    G +LERW+F++  +    E  +V  
Sbjct:  61 VKTFLTN-LTSQLSEWLEGGKLQRIVLVIMSKGT-GEVLERWNFNIITDGEVVEKGAVKE 118

Query: 120 RDESVVMREIQAIIRQITASVTFLPLLDEPCSFDLLVYTDPALEADANEWEESDAKLITA 179
           + +  +MREIQAI+RQ+ + ++FLP LDEPC FD+L YTD         W ESDAKLI  
Sbjct: 119 KSDKEIMREIQAIMRQVNSCISFLPCLDEPCIFDVLAYTDSDTTVPFT-WMESDAKLIEN 177

Query: 180 PRCEQVKLRSFTTNVHRVETGVAYACKELTD 210
           P  + VKL SF T +H+V+T V+Y   +L +
Sbjct: 178 P--QMVKLHSFDTKIHKVDTLVSYKVDDLDE 206



gb|AAD30555.1| cell cycle checkpoint protein MAD2 homolog [Zea mays]
sp|Q9XFH3|MAD2_MAIZE Mitotic spindle checkpoint protein MAD2
(208 aa)

Score: 153 bits (386), Expect: 3.65813e-36
Length: 208, Idn/Pos/Gap = 85/125/6 (40%/60%/2%)

Query:   1 MATAGSEQAPISLRGSTDTVIEFLRCAIYSILYQRGIYPPEMFRRASKFGTSVLVAQEAQ  60
           MA+  + +  I+LRGS   V EF   A  SILY R +YP E F +  K+G ++L+ Q+  
Sbjct:   1 MASRSASKDIITLRGSAAIVSEFFGYAANSILYNRAVYPEESFSKVKKYGLTMLLTQDEG  60

Query:  61 LDSYIERILQRHLRLWVLRGSVHRVVLAFAATADPGRILERWHFDLHMEQRATEDSSVP- 119
           + ++I   L   L  W+  G + R+VL   + A    +LERW+F++  +    E  ++  
Sbjct:  61 VKNFIAS-LTSQLSEWLEAGKLQRIVLVIMSKAT-SEVLERWNFNIVTDAEVVEKGAIKE 118

Query: 120 RDESVVMREIQAIIRQITASVTFLPLLDEPCSFDLLVYTDPALEADANEWEESDAKLITA 179
           + +  +MREIQAI+RQI + +T+LP LDEPC FD+L YTD  ++A    W ESDAKLI  
Sbjct: 119 KSDKEIMREIQAIMRQIASCITYLPCLDEPCVFDVLAYTDTDVDAPGT-WVESDAKLIDN 177

Query: 180 PRCEQVKLRSFTTNVHRVETGVAYACKE 207
           P  + VKL SF T +H+V+T V+Y   E
Sbjct: 178 P--QMVKLHSFDTKIHKVDTLVSYKKDE 203



emb|CAD41402.2| OJ000223_09.14 [Oryza sativa (japonica cultivar-group)]
ref|XP_472948.1| OJ000223_09.14 [Oryza sativa (japonica cultivar-group)]
(207 aa)

Score: 153 bits (386), Expect: 3.78228e-36
Length: 208, Idn/Pos/Gap = 85/124/6 (40%/59%/2%)

Query:   1 MATAGSEQAPISLRGSTDTVIEFLRCAIYSILYQRGIYPPEMFRRASKFGTSVLVAQEAQ  60
           MA+  + +  I+LRGS   V EF  CA  SILY RG+YP E F +  K+G ++L+ Q+  
Sbjct:   1 MASRTASKDIITLRGSAAIVSEFFVCAWRSILYNRGVYPEESFTKVKKYGLTMLLTQDEG  60

Query:  61 LDSYIERILQRHLRLWVLRGSVHRVVLAFAATADPGRILERWHFDLHMEQRATEDSSVP- 119
           + ++I   L   L  W+  G + R+VL   + A    +LERW+F +  +    +   +  
Sbjct:  61 VKTFIAN-LNTQLSEWLEAGKLQRIVLVIMSKAT-SEVLERWNFSIQTDPEVVDKGVIKE 118

Query: 120 RDESVVMREIQAIIRQITASVTFLPLLDEPCSFDLLVYTDPALEADANEWEESDAKLITA 179
           + +  +MREIQAI+RQ+ + +T+LP LDEPC FD+L YTD  + A    W ESDAKLI  
Sbjct: 119 KSDKEIMREIQAIMRQVASCITYLPCLDEPCIFDVLAYTDMDV-AVPFTWVESDAKLIEN 177

Query: 180 PRCEQVKLRSFTTNVHRVETGVAYACKE 207
           P  + VKL SF T +H+V+T V+Y   E
Sbjct: 178 P--QMVKLHSFDTKIHKVDTLVSYKVDE 203



emb|CAE68212.1| Hypothetical protein CBG13880 [Caenorhabditis briggsae]
(203 aa)

Score: 152 bits (383), Expect: 1.02086e-35
Length: 198, Idn/Pos/Gap = 81/123/7 (40%/62%/3%)

Query:   8 QAPISLRGSTDTVIEFLRCAIYSILYQRGIYPPEMFRRASKFGTSVLVAQEAQLDSYIER  67
           Q  I+L+GS   V EF    I SILYQR +YP + F+R  ++G ++ V  + +L ++++ 
Sbjct:   7 QNAITLKGSATLVKEFFHFGINSILYQRALYPADSFKREKRYGLALFVTHDKKLQAFMDP  66

Query:  68 ILQRHLRLWVLRGSVHRVVLAFAATADPGRILERWHFDLHMEQRATEDSSVPR--DESVV 125
            LQ+ +  W+ +  + R+V+  +       ++ERW FD+H E  A +  +  R  DE  +
Sbjct:  67 FLQQ-VEYWLAKKQLKRLVMVISEVKTK-EVVERWQFDIHTEDVAEDGENAHRVKDEKKI 124

Query: 126 MREIQAIIRQITASVTFLPLLDEPCSFDLLVYTDPALEADANEWEESDAKLITAPRCEQV 185
            +E+  ++RQITASV+FLPLL+EPCSFD+L+YT    +A   +W ES A LI  P  E V
Sbjct: 125 RQEMSDVLRQITASVSFLPLLEEPCSFDVLIYTGKDTQA-PEDWTESGACLI--PNSETV 181

Query: 186 KLRSFTTNVHRVETGVAY 203
           +LRSF+T+VH V T V Y
Sbjct: 182 QLRSFSTSVHGVNTNVQY 199



gb|AAK68576.1| Mad (yeast mitosis arrest deficient) related protein 2, isoform a [Caenorhabditis elegans]
gb|AAF63495.1| MDF-2 [Caenorhabditis elegans]
ref|NP_741342.1| yeast Mitosis Arrest DeFicient related, component of the spindle-assembly checkpoint, interacts with MDF-1, potential mitotic checkpoint component (23.5 kD) (mdf-2) [Caenorhabditis elegans]
(203 aa)

Score: 150 bits (378), Expect: 3.22872e-35
Length: 198, Idn/Pos/Gap = 84/123/7 (42%/62%/3%)

Query:   8 QAPISLRGSTDTVIEFLRCAIYSILYQRGIYPPEMFRRASKFGTSVLVAQEAQLDSYIER  67
           Q  ISL+GS   V EF    + SILYQR +YP + F+R  K+G ++ VA E +L ++++ 
Sbjct:   7 QNAISLKGSAQLVKEFFHFGLNSILYQRALYPSDSFKREKKYGLTLWVAHEKKLQAFMDP  66

Query:  68 ILQRHLRLWVLRGSVHRVVLAFAATADPGRILERWHFDLHMEQRATEDSSVPR--DESVV 125
           +LQ+ +  W+ +  + R+V+  +       ++ERW FD+H E  A E  +  R  +E  +
Sbjct:  67 LLQQ-VEYWLAKRQLKRLVMVISEVKTK-EVVERWQFDIHTENLAEEGENAHRVKEEKKI 124

Query: 126 MREIQAIIRQITASVTFLPLLDEPCSFDLLVYTDPALEADANEWEESDAKLITAPRCEQV 185
            +EI  +IRQITASV+FLPLL+EP SFD+L+YT    +A   +W ES A LI     E V
Sbjct: 125 RQEISDVIRQITASVSFLPLLEEPVSFDVLIYTGKDTQA-PEDWTESGACLIQ--NSETV 181

Query: 186 KLRSFTTNVHRVETGVAY 203
           +LRSF+T+VH V T V Y
Sbjct: 182 QLRSFSTSVHSVNTNVQY 199



emb|CAD79699.1| putative mitotic spindle checkpoint protein [Oryza sativa (indica cultivar-group)]
(221 aa)

Score: 146 bits (369), Expect: 3.78447e-34
Length: 222, Idn/Pos/Gap = 86/125/20 (38%/56%/9%)

Query:   1 MATAGSEQAPISLRGSTDTVIEF--------------LRCAIYSILYQRGIYPPEMFRRA  46
           MA+  + +  I+LRGS   V EF              L CA  SILY RG+YP E F + 
Sbjct:   1 MASRTASKDIITLRGSAAIVSEFFDSGLISDPGCFVFLVCAWRSILYNRGVYPEESFTKV  60

Query:  47 SKFGTSVLVAQEAQLDSYIERILQRHLRLWVLRGSVHRVVLAFAATADPGRILERWHFDL 106
            K+G ++L+ Q+  + ++I   L   L  W+  G + R+VL   + A    +LERW+F +
Sbjct:  61 KKYGLTMLLTQDEGVKTFIAN-LNTQLSEWLEAGKLQRIVLVIMSKAT-SEVLERWNFSI 118

Query: 107 HMEQRATEDSSVP-RDESVVMREIQAIIRQITASVTFLPLLDEPCSFDLLVYTDPALEAD 165
             +    +   +  + +  +MREIQAI+RQ+ + +T+LP LDEPC FD+L YTD  + A 
Sbjct: 119 QTDPEVVDKGVIKEKSDKEIMREIQAIMRQVASCITYLPCLDEPCIFDVLAYTDMDV-AV 177

Query: 166 ANEWEESDAKLITAPRCEQVKLRSFTTNVHRVETGVAYACKE 207
              W ESDAKLI  P  + VKL SF T +H+V+T V+Y   E
Sbjct: 178 PFTWVESDAKLIENP--QMVKLHSFDTKIHKVDTLVSYKVDE 217



ref|XP_517581.1| PREDICTED: similar to Mitotic spindle assembly checkpoint protein MAD2A (MAD2-like 1) (HsMAD2) [Pan troglodytes]
(299 aa)

Score: 146 bits (368), Expect: 4.547e-34
Length: 205, Idn/Pos/Gap = 85/124/26 (41%/60%/12%)

Query:   1 MATAGSEQAPISLRGSTDTVIEFLRCAIYSILYQRGIYPPEMFRRASKFGTSVLVAQEAQ  60
           MA   S +  I+LRGS + V EF    I SILYQRGIYP E F R  K+G ++LV  + +
Sbjct: 113 MALQLSREQGITLRGSAEIVAEFFSFGINSILYQRGIYPSETFTRVQKYGLTLLVTTDLE 172

Query:  61 LDSYIERILQRHLRLWVLRGSVHRVVLAFAATADPGRILERWHFDLHMEQRATEDSSVPR 120
           L  Y+  ++++ L+ W+ + SV ++V+   +  + G +LERW FD+  ++ A +DS+ PR
Sbjct: 173 LIKYLNNVVEQ-LKDWLYKCSVQKLVVVI-SNIESGEVLERWQFDIECDKTAKDDSA-PR 229

Query: 121 DES--VVMREIQAIIRQITASVTFLPLLDEPCSFDLLVYTDPALEADANEWEESDAKLIT 178
           ++S   +  EI+++IRQITA+VTFLPLL+  CSFDLL+YTD  L                
Sbjct: 230 EKSQKAIQDEIRSVIRQITATVTFLPLLEVSCSFDLLIYTDKDL---------------- 273

Query: 179 APRCEQVKLRSFTTNVHRVETGVAY 203
                 V  RSFTT +H+V + VAY
Sbjct: 274 -----VVPDRSFTTTIHKVNSMVAY 293



emb|CAA16846.1| mad2 [Schizosaccharomyces pombe]
sp|O14417|MAD2_SCHPO Mitotic spindle checkpoint component mad2
gb|AAB68597.1| spindle assembly checkpoint protein Mad2p [Schizosaccharomyces pombe]
ref|NP_596370.1| spindle assembly checkpoint protein mad2p [Schizosaccharomyces pombe]
(203 aa)

Score: 145 bits (366), Expect: 8.08643e-34
Length: 194, Idn/Pos/Gap = 79/125/7 (40%/64%/3%)

Query:  12 SLRGSTDTVIEFLRCAIYSILYQRGIYPPEMFRRASKFGTSVLVAQEAQLDSYIERILQR  71
           SL+GS+  V EF   A+ SIL+QRGIYP E F+   K+G ++LV+ + ++ +YI +I+ +
Sbjct:  11 SLKGSSKLVSEFFEYAVNSILFQRGIYPAEDFKVVRKYGLNMLVSVDEEVKTYIRKIVSQ  70

Query:  72 HLRLWVLRGSVHRVVLAFAATADPGRILERWHFDLHMEQRATEDSSV--PRDESVVMREI 129
            L  W+    + +++L   +    G  LERW F++ M   A +  ++    DE  V +EI
Sbjct:  71 -LHKWMFAKKIQKLILVITSKCS-GEDLERWQFNVEMVDTADQFQNIGNKEDELRVQKEI 128

Query: 130 QAIIRQITASVTFLPLLDEPCSFDLLVYTDPALEADANEWEESDAKLITAPRCEQVKLRS 189
           QA+IRQITA+VTFLP L+E C+F++LVY D   E    +W +SD +++     EQV+LRS
Sbjct: 129 QALIRQITATVTFLPQLEEQCTFNVLVYADKDSEV-PTDWVDSDPRILR--DAEQVQLRS 185

Query: 190 FTTNVHRVETGVAY 203
           F+T++H+++  VAY
Sbjct: 186 FSTSMHKIDCQVAY 199



gb|EAL21710.1| hypothetical protein CNBC5740 [Cryptococcus neoformans var. neoformans B-3501A]
gb|AAW42179.1| mitotic spindle checkpoint-related protein, putative [Cryptococcus neoformans var. neoformans JEC21]
ref|XP_569486.1| mitotic spindle checkpoint-related protein, putative [Cryptococcus neoformans var. neoformans JEC21]
(219 aa)

Score: 143 bits (361), Expect: 2.94728e-33
Length: 209, Idn/Pos/Gap = 83/125/14 (39%/59%/6%)

Query:  11 ISLRGSTDTVIEFLRCAIYSILYQRGIYPPEMFRRASKFGTSVLVAQEAQLDSYIERILQ  70
           I+L+GST  V EF   ++ SILYQRG+YP + FR   K+G  +LV  + +L  YI  +L 
Sbjct:  13 ITLKGSTALVTEFFEYSVNSILYQRGVYPSDDFRMVKKYGLPMLVTADEELKEYISTVLN  72

Query:  71 RHLRLWVLRGSVHRVVLAFAATADPGRILERWHFDLHMEQRATE-----------DSSVP 119
           + ++ W+L  S+ R+VLA   + + G  LERW FD++ ++ A                  
Sbjct:  73 Q-VQEWLLSSSLSRIVLAI-KSVETGETLERWQFDIYTDESALAPLPGGPPKSAGSKKKE 130

Query: 120 RDESVVMREIQAIIRQITASVTFLPLLDEPCSFDLLVYTDPALE-ADANEWEESDAKLIT 178
           + E  V  EI+ I++QIT+SVTFLP+L+E C+F +L +T+ + + A    W ++D  LI 
Sbjct: 131 KTEKEVQGEIREIMKQITSSVTFLPILEEQCTFTILAHTNDSPDVAIPATWNDADPHLID 190

Query: 179 APRCEQVKLRSFTTNVHRVETGVAYACKE 207
             + EQV+LRSF+TNVH +E  VAY   E
Sbjct: 191 KGKVEQVRLRSFSTNVHSLEAMVAYRVGE 219



emb|CAG87370.1| unnamed protein product [Debaryomyces hansenii CBS767]
ref|XP_459199.1| unnamed protein product [Debaryomyces hansenii]
(216 aa)

Score: 143 bits (360), Expect: 4.29028e-33
Length: 219, Idn/Pos/Gap = 84/134/16 (38%/61%/7%)

Query:   1 MATAGSEQAPISLRGSTDTVIEFLRCAIYSILYQRGIYPPEMFRRASKFGTSVLVAQEAQ  60
           M ++ S+ A ++L+GS   V ++   AI SIL+QRGIYPPE F    K+G  +LV+ +  
Sbjct:   1 MTSSSSQLAKLALKGSLKIVADYFEFAINSILFQRGIYPPEDFHTIKKYGLPLLVSADDD  60

Query:  61 LDSYIERILQRHLRLWVLRGSVHRVVLAFAATADPGRILERWHFDLHMEQ---RATEDS- 116
           + +YIE+I+ + ++ W+    + ++V+   + +    ++ERW F++ + Q      ED  
Sbjct:  61 VKAYIEKIMLQ-VKRWIYGRKIGKLVVVIISKST-AEVVERWEFNIEILQDNENNNEDDK 118

Query: 117 ---SVPRDESVVMREIQAIIRQITASVTFLPLLD-EPCSFDLLVYTDPALEAD--ANEWE 170
                PR+ES   REIQ IIRQIT+ V++LPLLD +  +F++LV+TDP  +     +EW 
Sbjct: 119 QEVEKPREES--HREIQMIIRQITSLVSYLPLLDVDEYTFNVLVHTDPNYDTAHIPHEWC 176

Query: 171 ESD--AKLITAPRCEQVKLRSFTTNVHRVETGVAYACKE 207
           ++D  AKLI     EQVK +SF+TN+H + T V+Y   E
Sbjct: 177 DTDGNAKLIEGNSIEQVKFKSFSTNIHEIGTTVSYKLDE 215



gb|AAW25990.1| unknown [Schistosoma japonicum]
(200 aa)

Score: 139 bits (349), Expect: 8.57776e-32
Length: 195, Idn/Pos/Gap = 76/117/5 (38%/60%/2%)

Query:   9 APISLRGSTDTVIEFLRCAIYSILYQRGIYPPEMFRRASKFGTSVLVAQEAQLDSYIERI  68
           + ISL+GS + + ++   A+ SILYQRGIYP   F++  K+  SVLV  +  L  Y+  I
Sbjct:   7 STISLKGSAELLTDYFFYALNSILYQRGIYPSASFKQNIKYDLSVLVTTDENLIKYLNVI  66

Query:  69 LQRHLRLWVLRGSVHRVVLAFAATADPGRILERWHFDLHMEQRATEDSSVPRDESVVMRE 128
           L + ++ W+  G+VHR+ L   +      +LERW FD+  E+  T +S   +  + +  E
Sbjct:  67 LDQ-VKKWLENGNVHRLALIIKSVKTE-EVLERWQFDMMTEKVDTNNSVGTKSLAQIQTE 124

Query: 129 IQAIIRQITASVTFLPLLDEPCSFDLLVYTDPALEADANEWEESDAKLITAPRCEQVKLR 188
           IQ +IRQI AS TFLP+L+  C+F+LLVY D  +    + WEE+  + I      ++KLR
Sbjct: 125 IQGVIRQIVASNTFLPVLNNSCTFELLVYADRNINVPTS-WEETGPQFIV--NSAEIKLR 181

Query: 189 SFTTNVHRVETGVAY 203
           S +T +HRV+  V+Y
Sbjct: 182 SISTTLHRVDHTVSY 196



gb|AAQ89630.1| At3g25980 [Arabidopsis thaliana]
dbj|BAB01061.1| cell cycle checkpoint protein MAD2-like [Arabidopsis thaliana]
ref|NP_189227.1| mitotic spindle checkpoint protein, putative (MAD2) [Arabidopsis thaliana]
dbj|BAD44126.1| putative mitotic checkpoint protein [Arabidopsis thaliana]
dbj|BAD43059.1| putative mitotic checkpoint protein [Arabidopsis thaliana]
sp|Q9LU93|MAD2_ARATH Mitotic spindle checkpoint protein MAD2
(209 aa)

Score: 138 bits (348), Expect: 9.4023e-32
Length: 199, Idn/Pos/Gap = 83/116/8 (41%/58%/4%)

Query:  11 ISLRGSTDTVIEFLRCAIYSILYQRGIYPPEMFRRASKFGTSVLVAQEAQLDSYIERILQ  70
           I+L GS   V EF   A  SILY R +YP E F +  K+G  +L+ ++  + S++   L 
Sbjct:  12 ITLHGSAAIVSEFFCYAANSILYNRAVYPEESFVKVKKYGLPMLLIEDESVKSFMSN-LT  70

Query:  71 RHLRLWVLRGSVHRVVLAFAATADPGRILERWHFDLHMEQRATEDSSVPRDES--VVMRE 128
             +  W+  G + RVVL   + A  G +LERW+F +  +     D  V R++S   +MRE
Sbjct:  71 SQISEWLEAGKLQRVVLVIMSKAT-GEVLERWNFRIETDNEVV-DKGVSREKSDKEIMRE 128

Query: 129 IQAIIRQITASVTFLPLLDEPCSFDLLVYTDPALEADANEWEESDAKLITAPRCEQVKLR 188
           IQAI+RQ+ +SVT+LP LDE C FD+L YTD  + A    W ESD KLI  P  + VKL 
Sbjct: 129 IQAIMRQVASSVTYLPCLDETCVFDVLAYTDTDV-AVPFTWIESDPKLIANP--QMVKLH 185

Query: 189 SFTTNVHRVETGVAYACKE 207
            F T +H+V+T V+Y   E
Sbjct: 186 GFDTKIHKVDTLVSYKNDE 204



gb|EAA38088.1| GLP_127_6168_5557 [Giardia lamblia ATCC 50803]
(203 aa)

Score: 135 bits (341), Expect: 5.99354e-31
Length: 205, Idn/Pos/Gap = 82/120/7 (40%/58%/3%)

Query:   4 AGSEQAPISLRGSTDTVIEFLRCAIYSILYQRGIYPPEMFRRASKFGTSVLVAQEAQLDS  63
           A   +  I+LRGST  V E+   +I SILY RGIY  + F    K+G  ++VA++  L  
Sbjct:   2 ATQTKNAITLRGSTAIVTEYFAYSINSILYLRGIYGQDSFMSQQKYGLPLMVAKDPALSK  61

Query:  64 YIERILQRHLRLWVLRGSVHRVVLAFAATADPGRILERWHFDLHMEQ-RATEDSSVPRDE 122
           Y+  +LQR +  W++ G V ++V+          I E+W F++  E  +A   SS P  E
Sbjct:  62 YLGEVLQR-VAEWLMSGKVQKLVMVLLPIGGSEPI-EKWEFNVENEGVQAGATSSKP--E 117

Query: 123 SVVMREIQAIIRQITASVTFLPLLDEPCSFDLLVYTDPALEADANEWEESDAKLITAPRC 182
           + V REIQAI+RQI ASV+FLP++ +P +FD+++YTD A+   A EWEE   +       
Sbjct: 118 ADVQREIQAILRQINASVSFLPVISDPVTFDIMIYTDAAVPTPA-EWEECPGRDHVHNAV 176

Query: 183 EQVKLRSFTTNVHRVETGVAYACKE 207
           E VK R F+T +H+V+T V Y   E
Sbjct: 177 E-VKFRDFSTKIHKVDTAVIYKSGE 200



gb|AAS51270.1| ACR043Wp [Ashbya gossypii ATCC 10895]
ref|NP_983446.1| ACR043Wp [Eremothecium gossypii]
(199 aa)

Score: 133 bits (335), Expect: 3.07551e-30
Length: 200, Idn/Pos/Gap = 83/120/14 (41%/60%/7%)

Query:  10 PISLRGSTDTVIEFLRCAIYSILYQRGIYPPEMFRRASKFGTSVLVAQEAQLDSYIERIL  69
           PISL+GST  V EF   +I SILYQR +YPPE F    K+  ++L   + +L  YI +IL
Sbjct:   4 PISLKGSTRMVTEFFEYSINSILYQRAVYPPEDFTTVKKYDLNLLKTHDEELKEYIRKIL  63

Query:  70 QRHLRLWVLRGSVHRVVLAFAATADPGRILERWHFDLHMEQRATEDSSVPR-DESVVMRE 128
            +  R W+L G  +++VL      D G +LERW F++   +RA +++++   D     ++
Sbjct:  64 LQVHR-WLLGGKCNKLVLVI-LDKDEGEVLERWEFNVQRSERAPQEAALESADLEETQKQ 121

Query: 129 IQAIIRQITASVTFLPLL--DEPCSFDLLVYTDPALEADAN---EWEESDAKLITAPRCE 183
           I+A+IRQITASVTFLP L  +   +F++L YTD    A+AN   EW +SDA+ I     E
Sbjct: 122 IRALIRQITASVTFLPELANEGNYTFNVLAYTD----ANANVPMEWVDSDARDID--NAE 175

Query: 184 QVKLRSFTTNVHRVETGVAY 203
            V+ R+F T  H V   V+Y
Sbjct: 176 VVQFRNFNTGDHSVNAQVSY 195



emb|CAH00578.1| unnamed protein product [Kluyveromyces lactis NRRL Y-1140]
ref|XP_453482.1| unnamed protein product [Kluyveromyces lactis]
(196 aa)

Score: 132 bits (332), Expect: 8.16364e-30
Length: 201, Idn/Pos/Gap = 84/118/18 (41%/58%/8%)

Query:  11 ISLRGSTDTVIEFLRCAIYSILYQRGIYPPEMFRRASKFGTSVLVAQEAQLDSYIERILQ  70
           ISL+GST  V EF   +I SILYQR +YP E F    K+  S+L  Q+ +L  YI  IL 
Sbjct:   4 ISLKGSTRIVTEFFEYSINSILYQRAVYPAEDFATVKKYDLSLLKTQDTELKQYIREIL-  62

Query:  71 RHLRLWVLRGSVHRVVLAFAATADPGRILERWHF--DLHMEQRATEDS-SVPRDESVVMR 127
           R +  W+L G  H++VL      D G  +ERW F  D H  +  T+D  ++P +E+   +
Sbjct:  63 RQVHRWLLGGKCHQLVLCI-VDKDDGETIERWKFNVDSHSNKNDTDDDMNIPLEET--QK 119

Query: 128 EIQAIIRQITASVTFLPLLDEP--CSFDLLVYTDPALEADAN---EWEESDAKLITAPRC 182
           EI+A++RQITASVTFLP L      +F++L YTD    ++AN   EW +SD+K I   + 
Sbjct: 120 EIRAVLRQITASVTFLPELKNEGNYTFNVLAYTD----SNANVPLEWTDSDSKEIA--KG 173

Query: 183 EQVKLRSFTTNVHRVETGVAY 203
           E V+ +SF T+ + V   V Y
Sbjct: 174 ESVQFKSFGTSAYSVGAEVTY 194



ref|XP_325636.1| hypothetical protein [Neurospora crassa]
gb|EAA30805.1| hypothetical protein [Neurospora crassa]
(244 aa)

Score: 130 bits (326), Expect: 3.91858e-29
Length: 229, Idn/Pos/Gap = 81/126/44 (35%/55%/19%)

Query:  11 ISLRGSTDTVIEFLRCAIYSILYQRGIYPPEMFRRASKFGTSVLVAQEAQLDSYIERILQ  70
           +SL+GS   V EF + +I++IL+QRG+YP E F    K+G ++LV+ + Q+ +YI+RI+ 
Sbjct:  20 LSLKGSAKLVAEFFQYSIHTILFQRGVYPAEDFTTVKKYGLNMLVSADDQVRAYIKRIMS  79

Query:  71 RHLRLWVLRGSVHRVVLAFAATADPGRILERWHFDLHMEQRATEDSS------------- 117
           + L  W++   + ++V+      D G  +ERW FD+ +  +A +  +             
Sbjct:  80 Q-LHKWMVGSKISKLVIVI-TDKDTGEHVERWQFDVQIFSKAAQSKTKSQPASATTDDNQ 137

Query: 118 --------------------VPRDESVVMREIQAIIRQITASVTFLPLLDEPCSFDLLVY 157
                               + + E+ +  EI AI RQITASVTFLP L   C+F++LVY
Sbjct: 138 NQSPNENAAASTAASTPTPPLDKTEAEIQAEIAAIFRQITASVTFLPQLSGDCTFNVLVY 197

Query: 158 TDPALEADAN---EWEESDAKLITAPRCEQVKLRSFTTNVHRVETGVAY 203
            D    AD++   EW +SDAK I     E+V+LR F+T  HRV+T V+Y
Sbjct: 198 AD----ADSDVPVEWGDSDAKEIV--NGERVQLRGFSTTNHRVDTLVSY 240



ref|NP_647991.1| CG17498-PA [Drosophila melanogaster]
gb|AAF50740.1| CG17498-PA [Drosophila melanogaster]
gb|AAL48090.1| RE72064p [Drosophila melanogaster]
(207 aa)

Score: 129 bits (324), Expect: 6.74009e-29
Length: 208, Idn/Pos/Gap = 67/130/10 (32%/62%/4%)

Query:   1 MATAGSEQAPISLRGSTDTVIEFLRCAIYSILYQRGIYPPEMFRRASKFGTSVLVAQEAQ  60
           M+TA + +  I+L+GS   ++E+L+  I SIL+QRGIYP E F    ++G ++L++++ +
Sbjct:   1 MSTAQATKNCITLKGSAQIIVEYLKYGINSILFQRGIYPAEDFNNTQQYGLTILMSKDPK  60

Query:  61 LDSYIERILQRHLRLWVLRGSVHRVVLAFAATADPGRILERWHFDLHMEQRATEDS---- 116
           + ++++ +L +    W+ +  ++++ +     A    +LE W F++  E    + S    
Sbjct:  61 IKTFLQNVLSQ-TEEWLSKNMINKISMVI-TNAHTKEVLECWDFNMQAELGDGDISDPTK 118

Query: 117 -SVPRDESVVMREIQAIIRQITASVTFLPLLDEPCSFDLLVYTDPALEADANEWEESDAK 175
            +  ++ S +  EI+ ++RQI+A+V++LPLLD  C+FD++++T    E  A +W+E+ A 
Sbjct: 119 ATTTKELSRIQNEIRDVMRQISATVSYLPLLDCICTFDIMIHTLQNTELPA-KWDETGAI 177

Query: 176 LITAPRCEQVKLRSFTTNVHRVETGVAY 203
           +I  P  + V+LRSF+T +H+V+T V Y
Sbjct: 178 VIQNP--QAVQLRSFSTGLHKVDTVVNY 203



gb|EAL30208.1| GA14530-PA [Drosophila pseudoobscura]
(207 aa)

Score: 128 bits (322), Expect: 1.02294e-28
Length: 208, Idn/Pos/Gap = 67/132/10 (32%/63%/4%)

Query:   1 MATAGSEQAPISLRGSTDTVIEFLRCAIYSILYQRGIYPPEMFRRASKFGTSVLVAQEAQ  60
           M++A + +  I+L+GS   ++E+L+  I+SIL+QRGIYP E F    ++G ++L++++ +
Sbjct:   1 MSSAQATKNCITLKGSAQIIVEYLKYGIHSILFQRGIYPAENFDSTQQYGLTILMSKDPK  60

Query:  61 LDSYIERILQRHLRLWVLRGSVHRVVLAFAATADPGRILERWHFDLHME---QRATEDS- 116
           + ++++ +L +    W+ +  ++++ +     A    +LE W F +  E    +A + S 
Sbjct:  61 ITTFLQNVLSQ-TEEWLSKNMINKISMVI-TNAHSKEVLECWDFKMQAENGDNQAADPSQ 118

Query: 117 -SVPRDESVVMREIQAIIRQITASVTFLPLLDEPCSFDLLVYTDPALEADANEWEESDAK 175
            +  +D++ +  EI+ ++RQI+A+V++LPLLD  C+FD++++T    E  A +W+E+ A 
Sbjct: 119 RTSSKDQTRIQNEIRDVMRQISATVSYLPLLDCICTFDVMIHTLDNTELPA-KWDETGAI 177

Query: 176 LITAPRCEQVKLRSFTTNVHRVETGVAY 203
           +I     + V+LRSF+T +H+VET V Y
Sbjct: 178 VIQ--NAQAVQLRSFSTGLHKVETVVNY 203



emb|CAA89321.1| MAD2 [Saccharomyces cerevisiae]
sp|P40958|MAD2_YEAST Mitotic spindle checkpoint component MAD2 (Mitotic MAD2 protein)
gb|AAS56569.1| YJL030W [Saccharomyces cerevisiae]
ref|NP_012504.1| Component of the spindle-assembly checkpoint complex, which delays the onset of anaphase in cells with defects in mitotic spindle assembly; forms a complex with Mad1p [Saccharomyces cerevisiae]
gb|AAA21385.1| This is the correct MAD2 coding sequence.; Mutations in this gene inactivate the spindle assembly checkpoint
(196 aa)

Score: 126 bits (317), Expect: 3.72832e-28
Length: 199, Idn/Pos/Gap = 81/118/15 (40%/59%/7%)

Query:  11 ISLRGSTDTVIEFLRCAIYSILYQRGIYPPEMFRRASKFGTSVLVAQEAQLDSYIERILQ  70
           ISL+GST TV EF   +I SILYQRG+YP E F    K+  ++L   + +L  YI +IL 
Sbjct:   5 ISLKGSTRTVTEFFEYSINSILYQRGVYPAEDFVTVKKYDLTLLKTHDDELKDYIRKILL  64

Query:  71 RHLRLWVLRGSVHRVVLAFAATADPGRILERWHFDL-HMEQRATEDSSVPRDESVVMREI 129
           +  R W+L G  +++VL      D G ++ERW F++ H+   +     V  D +    +I
Sbjct:  65 QVHR-WLLGGKCNQLVLCI-VDKDEGEVVERWSFNVQHISGNSNGQDDVV-DLNTTQSQI 121

Query: 130 QAIIRQITASVTFLPLLDEP--CSFDLLVYTDPALEADAN---EWEESDAKLITAPRCEQ 184
           +A+IRQIT+SVTFLP L +    +F +L YTD    ADA    EW +S++K I  P  E 
Sbjct: 122 RALIRQITSSVTFLPELTKEGGYTFTVLAYTD----ADAKVPLEWADSNSKEI--PDGEV 175

Query: 185 VKLRSFTTNVHRVETGVAY 203
           V+ ++F+TN H+V   V+Y
Sbjct: 176 VQFKTFSTNDHKVGAQVSY 194



ref|XP_393696.1| similar to CG17498-PA [Apis mellifera]
(214 aa)

Score: 126 bits (316), Expect: 5.89948e-28
Length: 199, Idn/Pos/Gap = 69/117/15 (34%/58%/7%)

Query:  11 ISLRGSTDTVIEFLRCAIYSILYQRGIYPPEMFRRASKFGTSVLVAQEAQLDSYIERILQ  70
           I+L+GS + V E+L   + SILYQRGIYPPE F  A  FG  VL++ + ++  ++  +L 
Sbjct:  11 ITLKGSAELVKEYLLYGVNSILYQRGIYPPETFEHAEHFGLFVLMSTDEKIKGFLNTVLG  70

Query:  71 RHLRLWVLRGSVHRVVLAFAATADPGRILERWHFDLHMEQRATEDSSVP----------R 120
           + ++ W+++  V ++ L      +   +LE+W F +  E + +  ++            +
Sbjct:  71 Q-IQEWLVQRKVQKITLVI-TNVNTKEVLEKWDFKVDYEGQTSNSTNDNTNNSFPEVGTK 128

Query: 121 DESVVMREIQAIIRQITASVTFLPLLDEPCSFDLLVYTDPALEADANEWEESDAKLITAP 180
           D   + +EI+ +IRQIT +V+FLPLLD  CSFD+L YT P       EW+E+    I   
Sbjct: 129 DVKTIQKEIREVIRQITGTVSFLPLLDCLCSFDILTYTVPDC-GIPKEWDETQPVFIA-- 185

Query: 181 RCEQVKLRSFTTNVHRVET 199
             ++V+LRSF+T++H+++T
Sbjct: 186 NSQEVQLRSFSTSLHKMDT 204



emb|CAG60706.1| unnamed protein product [Candida glabrata CBS138]
ref|XP_447759.1| unnamed protein product [Candida glabrata]
(195 aa)

Score: 124 bits (311), Expect: 1.78961e-27
Length: 198, Idn/Pos/Gap = 79/115/14 (39%/58%/7%)

Query:  11 ISLRGSTDTVIEFLRCAIYSILYQRGIYPPEMFRRASKFGTSVLVAQEAQLDSYIERILQ  70
           +SL+GST ++ EF    I SIL+QRG+YPPE F    K+  S+L   + +L  Y+ +IL 
Sbjct:   5 LSLKGSTRSITEFFEYCINSILFQRGVYPPEDFSTVRKYELSLLRTHDDELKDYLRKILS  64

Query:  71 RHLRLWVLRGSVHRVVLAFAATADPGRILERWHFDLHMEQRATEDSSVPRDESVVMREIQ 130
           +  R W+L G  +++VL      D G ++ERW FD+    +  E ++   DE     +++
Sbjct:  65 QVHR-WLLGGKCNKLVLCI-VDKDDGEVVERWQFDVTHFSKEQETAAEVTDEE-TRNQMR 121

Query: 131 AIIRQITASVTFLPLL--DEPCSFDLLVYTDPALEADAN---EWEESDAKLITAPRCEQV 185
            +I+QITASVTFLP L  +   +F +L YTD    ADA    EW +SD+K +     E V
Sbjct: 122 TLIKQITASVTFLPELVKEGGYTFTVLAYTD----ADAKVPLEWGDSDSKEVKDG--EIV 175

Query: 186 KLRSFTTNVHRVETGVAY 203
           + RSF TN HRV   V+Y
Sbjct: 176 QFRSFETNDHRVGAQVSY 193



gb|EAK94586.1| hypothetical protein CaO19.8642 [Candida albicans SC5314]
(212 aa)

Score: 120 bits (301), Expect: 3.29162e-26
Length: 212, Idn/Pos/Gap = 67/120/12 (31%/56%/5%)

Query:   1 MATAGSEQAPISLRGSTDTVIEFLRCAIYSILYQRGIYPPEMFRRASKFGTSVLVAQEAQ  60
           M ++    + ++L+GS+  V ++   A+ SILYQRGIYP E F    K+   +++  +  
Sbjct:   1 MPSSLEPSSKLALKGSSKIVCDYFEFALNSILYQRGIYPQEDFVTVKKYDLPMVINDDYD  60

Query:  61 LDSYIERILQRHLRLWVLRGSVHRVVLAFAATADPGRILERWHFDLHM--EQRATED--- 115
           +  YI  I+ + ++ W+    + + ++   +  +   I ERW F++    ++  TE+   
Sbjct:  61 VQKYINNIM-KQIKKWIYGSLMSKFIIVIVSKTNLENI-ERWEFNIETKDQEETTENGDG 118

Query: 116 SSVPRDESVVMREIQAIIRQITASVTFLPLL--DEPCSFDLLVYTDPALEADANEW--EE 171
             V +    + +EI+AIIRQIT+SV++LP+L  D+  +F++LVYTDP       EW   +
Sbjct: 119 DGVGKSRQEIQKEIRAIIRQITSSVSYLPVLKDDDEYTFNVLVYTDPNTSIPI-EWCDTQ 177

Query: 172 SDAKLITAPRCEQVKLRSFTTNVHRVETGVAY 203
            D K++     + VK  SF+T++H+V T V+Y
Sbjct: 178 GDGKVLDGDNVDNVKFTSFSTDIHQVGTSVSY 209



gb|EAK94540.1| hypothetical protein CaO19.1040 [Candida albicans SC5314]
(214 aa)

Score: 115 bits (288), Expect: 9.4214e-25
Length: 214, Idn/Pos/Gap = 66/119/14 (30%/55%/6%)

Query:   1 MATAGSEQAPISLRGSTDTVIEFLRCAIYSILYQRGIYPPEMFRRASKFGTSVLVAQEAQ  60
           M ++    + ++L+GS+  V ++   A+ SILYQRGIYP E F    K+   +++  +  
Sbjct:   1 MPSSLEPSSKLALKGSSKIVCDYFEFALNSILYQRGIYPQEDFVTVKKYDLPMVINDDYD  60

Query:  61 LDSYIERILQRHLRLWVLRGSVHRVVLAFAATADPGRILERWHFDLHM--EQRATED--- 115
           +  YI  I+ + ++ W+    + + ++   +  +   I ERW F++    ++  TE+   
Sbjct:  61 VQKYINNIM-KQIKKWIYGSLMSKFIIVIVSKTNLENI-ERWEFNIETKDQEETTENGDG 118

Query: 116 --SSVPRDESVVMREIQAIIRQITASVTFLPLL--DEPCSFDLLVYTDPALEADANEW-- 169
               V +    + +EI+ IIRQIT+SV++LP+L  D+  +F++LVYTDP       EW  
Sbjct: 119 DGDGVGKSRQEIQKEIRTIIRQITSSVSYLPVLKDDDEYTFNVLVYTDPNTSVPI-EWCD 177

Query: 170 EESDAKLITAPRCEQVKLRSFTTNVHRVETGVAY 203
            + D K++     + VK  SF+T++H+V T V+Y
Sbjct: 178 TQGDGKVLDGDNVDNVKFTSFSTDIHQVGTSVSY 211



gb|EAA06865.3| ENSANGP00000017449 [Anopheles gambiae str. PEST]
ref|XP_311286.2| ENSANGP00000017449 [Anopheles gambiae str. PEST]
(209 aa)

Score: 104 bits (259), Expect: 1.96505e-21
Length: 206, Idn/Pos/Gap = 59/119/8 (28%/57%/3%)

Query:   4 AGSEQAPISLRGSTDTVIEFLRCAIYSILYQRGIYPPEMFRRASKFGTSVLVAQEAQLDS  63
           A S+   I+L+GS   + E+L+ + +SI++QRGIYP   F+     G  ++V+++ ++  
Sbjct:   2 ATSQDHCITLQGSAAIIHEYLKYSSHSIIFQRGIYPASDFQPIDYNGVPMMVSRDPRIKE  61

Query:  64 YIERILQRHLRLWVLRGSVHRVVLAFAATADPGRILERWHFDLH--MEQRATEDSSVPRD 121
           YI+ I+++   L +++  + +V +    T +   ++ERW F++    +    E+ +VP++
Sbjct:  62 YIDLIMEQVHDL-IMKRMITKVTMCIV-TVESKEVVERWDFNIQPTYDGEQGEEPAVPKE 119

Query: 122 ESVVMREIQAIIRQITASVTFLPLLDEPCSFDLLVYT-DPALEADAN---EWEESDAKLI 177
              +  EI+ ++RQI A+++FLP LD+ C+FD++++T     EA+     ++ E D   I
Sbjct: 120 LKKIQSEIRDVMRQIVATISFLPCLDQRCTFDIMLHTVGEVFEANPTMIKQFREEDMASI 179

Query: 178 TAPRCEQVKLRSFTTNVHRVETGVAY 203
                + + L+ F+T +  V+T V Y
Sbjct: 180 EIEGAQTIALKQFSTGLQTVDTKVVY 205



gb|EAA69918.1| hypothetical protein FG02639.1 [Gibberella zeae PH-1]
ref|XP_382815.1| hypothetical protein FG02639.1 [Gibberella zeae PH-1]
(207 aa)

Score: 101 bits (251), Expect: 1.71997e-20
Length: 176, Idn/Pos/Gap = 66/99/25 (37%/56%/14%)

Query:  48 KFGTSVLVAQEAQLDSYIERILQRHLRLWVLRGSVHRVVLAFAATADPGRILERWHFDLH 107
           K+G ++LV+ + Q+ +YI++I+ + L  W++ G + ++V+      D G  +ERW FD+ 
Sbjct:  33 KYGLNMLVSADDQVKAYIKKIMSQ-LDKWMVGGKISKLVIVIT-DKDTGEHVERWQFDVQ  90

Query: 108 MEQ---------RATEDSSVP-----------RDESVVMREIQAIIRQITASVTFLPLLD 147
           + Q          A +D   P           + E  +  EI AI RQITASVTFLP L+
Sbjct:  91 IFQPVKKSKSSKSAPKDQENPAAGSAAPTAPEKTEPEIQAEIAAIFRQITASVTFLPQLN 150

Query: 148 EPCSFDLLVYTDPALEADANEWEESDAKLITAPRCEQVKLRSFTTNVHRVETGVAY 203
             C+F++LVY D   E    EW +SDAK I     E+V+LR F+T  HRV+T V+Y
Sbjct: 151 GDCTFNVLVYADADSEVPV-EWGDSDAKEIE--NGEKVQLRGFSTANHRVDTLVSY 203



dbj|BAB25799.1| unnamed protein product [Mus musculus]
(105 aa)

Score: 92 bits (229), Expect: 6.1174e-18
Length: 102, Idn/Pos/Gap = 53/72/6 (51%/70%/5%)

Query: 104 FDLHMEQRATEDSSVPRDES--VVMREIQAIIRQITASVTFLPLLDEPCSFDLLVYTDPA 161
           FD+  E+ A E+  V R++S   +  EI+++IRQITA+VTFLPLL+  CSFDLL+YTD  
Sbjct:   2 FDIECEKTAKEEG-VRREKSQKAIQDEIRSVIRQITATVTFLPLLEVSCSFDLLIYTDKD  60

Query: 162 LEADANEWEESDAKLITAPRCEQVKLRSFTTNVHRVETGVAY 203
           L     +WEES  + IT   CE+V+LRSFTT +H+V + VAY
Sbjct:  61 LVV-PEKWEESGPQFIT--NCEEVRLRSFTTTIHKVNSMVAY  99



gb|EAA57300.1| hypothetical protein MG08269.4 [Magnaporthe grisea 70-15]
ref|XP_362779.1| hypothetical protein MG08269.4 [Magnaporthe grisea 70-15]
(236 aa)

Score: 92 bits (228), Expect: 7.98958e-18
Length: 227, Idn/Pos/Gap = 75/111/35 (33%/48%/15%)

Query:  11 ISLRGSTDTVIEF-LRCAIYSILYQRGIYPPEMFRRASKFGT-SVLVAQEAQLDSYIERI  68
           +SL+GS   V EF     +        + PP+ F            V+ + Q+ +YI++I
Sbjct:  18 LSLKGSAKLVAEFKYGLNMLGTAMNSPLRPPQAFPHPQNAADPRTTVSADDQVKAYIKKI  77

Query:  69 LQRHLRLWVLRGSVHRVVLAFAATADPGRILERWHFDLHM-----------------EQR 111
           + + L  W+++G + ++V+      D G  +ERW FD+ +                    
Sbjct:  78 MSQ-LDRWMVKGKISKLVIVIT-DKDTGEHVERWQFDVQIFGGSSKKSKSSSKSAASASA 135

Query: 112 ATEDSSVP--------RDESVVMREIQAIIRQITASVTFLPLLDEPCSFDLLVYTDPALE 163
             E+SS          + E+ +  EI AI RQITASVTFLP L   C+F++LVY D   E
Sbjct: 136 GQENSSAASDAAQAPEKTEAEIQAEIAAIFRQITASVTFLPQLAGDCTFNVLVYADADSE 195

Query: 164 ADANEWEESDAKLITAPRCEQVKLRSFTTNVHRVETGVAYACKELTD 210
               EW +SDAK I     E+V+LR F+T  HRV+T V+Y    LTD
Sbjct: 196 VPV-EWGDSDAKEIE--NGERVQLRGFSTASHRVDTLVSY---RLTD 236



ref|XP_533306.1| PREDICTED: similar to Mitotic spindle assembly checkpoint protein MAD2A (MAD2-like 1) (HsMAD2) [Canis familiaris]
(306 aa)

Score: 82 bits (203), Expect: 6.54537e-15
Length: 87, Idn/Pos/Gap = 45/60/5 (51%/68%/5%)

Query: 119 PRDES--VVMREIQAIIRQITASVTFLPLLDEPCSFDLLVYTDPALEADANEWEESDAKL 176
           PR+ S   +  EI +IIRQIT +VTFLPLL+  CSFDLL+YTD  L     +WEES  + 
Sbjct: 217 PREMSQKAIQDEILSIIRQITVTVTFLPLLEVSCSFDLLIYTDKDLVV-LEKWEESGPQF 275

Query: 177 ITAPRCEQVKLRSFTTNVHRVETGVAY 203
           +T    E+V+LRSF+T +H+V + VAY
Sbjct: 276 VT--NSEEVRLRSFSTTIHKVNSMVAY 300



ref|XP_537930.1| PREDICTED: similar to Mitotic spindle assembly checkpoint protein MAD2A (MAD2-like 1) (HsMAD2) [Canis familiaris]
(97 aa)

Score: 82 bits (201), Expect: 1.2974e-14
Length: 91, Idn/Pos/Gap = 45/64/5 (49%/70%/5%)

Query: 115 DSSVPRDES--VVMREIQAIIRQITASVTFLPLLDEPCSFDLLVYTDPALEADANEWEES 172
           D + PR++S   +  EI ++I+QITA+VTFLPLL+  CSFDLL+YTD  L     +WEES
Sbjct:   4 DLNTPREKSQKAIQDEILSVIQQITATVTFLPLLEVSCSFDLLIYTDKDLVV-LEKWEES  62

Query: 173 DAKLITAPRCEQVKLRSFTTNVHRVETGVAY 203
             + +T    E+V+LRSF+T +H+V + VAY
Sbjct:  63 GPQFVT--NSEEVRLRSFSTTIHKVNSMVAY  91



gb|AAM15619.1| Mad (yeast mitosis arrest deficient) related protein 2, isoform b [Caenorhabditis elegans]
(116 aa)

Score: 80 bits (197), Expect: 3.01343e-14
Length: 107, Idn/Pos/Gap = 39/64/2 (36%/59%/1%)

Query:   8 QAPISLRGSTDTVIEFLRCAIYSILYQRGIYPPEMFRRASKFGTSVLVAQEAQLDSYIER  67
           Q  ISL+GS   V EF    + SILYQR +YP + F+R  K+G ++ VA E +L ++++ 
Sbjct:   7 QNAISLKGSAQLVKEFFHFGLNSILYQRALYPSDSFKREKKYGLTLWVAHEKKLQAFMDP  66

Query:  68 ILQRHLRLWVLRGSVHRVVLAFAATADPGRILERWHFDLHMEQRATE 114
           +LQ+ +  W+ +  + R+V+  +       ++ERW FD+H E  A E
Sbjct:  67 LLQQ-VEYWLAKRQLKRLVMVISEVKTK-EVVERWQFDIHTENLAEE 111



gb|AAW79034.1| GekBS188P [Gekko japonicus]
(102 aa)

Score: 73 bits (178), Expect: 6.12805e-12
Length: 90, Idn/Pos/Gap = 36/56/1 (40%/62%/1%)

Query:  1 MATAGSEQAPISLRGSTDTVIEFLRCAIYSILYQRGIYPPEMFRRASKFGTSVLVAQEAQ 60
          MA   S +  I+LRGS + V EF    I SILYQRGIYP E F R  K+G ++LV  + +
Sbjct:  1 MALQLSREQGITLRGSAEIVAEFFSFGINSILYQRGIYPSETFTRVQKYGLTLLVTTDPE 60

Query: 61 LDSYIERILQRHLRLWVLRGSVHRVVLAFA 90
          L  Y+  ++++ L+ W+ + SV ++V+  +
Sbjct: 61 LIKYLNNVVEQ-LKEWLYKCSVQKLVVVIS 89



gb|AAN74648.1| MAD2 mitotic arrest deficient-like 1 variant [Homo sapiens]
(90 aa)

Score: 63 bits (154), Expect: 3.04309e-09
Length: 71, Idn/Pos/Gap = 31/44/0 (43%/61%/0%)

Query:  1 MATAGSEQAPISLRGSTDTVIEFLRCAIYSILYQRGIYPPEMFRRASKFGTSVLVAQEAQ 60
          MA   S +  I+LRGS + V EF    I SILYQRGIYP E F R  K+G ++LV  + +
Sbjct:  1 MALQLSREQGITLRGSAEIVAEFFSFGINSILYQRGIYPSETFTRVQKYGLTLLVTTDLE 60

Query: 61 LDSYIERILQR 71
          L  Y+  ++++
Sbjct: 61 LIKYLNNVVEQ 71



dbj|BAC56442.1| similar to MAD2 protein [Bos taurus]
(77 aa)

Score: 62 bits (149), Expect: 1.27815e-08
Length: 69, Idn/Pos/Gap = 29/43/1 (42%/62%/1%)

Query: 15 GSTDTVIEFLRCAIYSILYQRGIYPPEMFRRASKFGTSVLVAQEAQLDSYIERILQRHLR 74
          G+  +V EF    I SILYQRGIYP E F R  K+G ++LV  + +L  Y+  ++ + L+
Sbjct:  1 GAPRSVAEFFSFGINSILYQRGIYPSETFTRVQKYGLTLLVTTDPELIKYLNNVVDQ-LK 59

Query: 75 LWVLRGSVH 83
           W+ + SVH
Sbjct: 60 EWLYKCSVH 68



gb|EAK82558.1| hypothetical protein UM01742.1 [Ustilago maydis 521]
ref|XP_399357.1| hypothetical protein UM01742.1 [Ustilago maydis 521]
(434 aa)

Score: 48 bits (115), Expect: 9.71638e-05
Length: 81, Idn/Pos/Gap = 25/45/1 (30%/55%/1%)

Query:   7 EQAPISLRGSTDTVIEFLRCAIYSILYQRGIYPPEMFRRASKFGTSVLVAQEAQLDSYIE  66
           E +P+S       +I+FL  A ++IL  R +YP ++F R  K+      ++   L+ YI 
Sbjct:  24 EDSPLSYNQLVSGIIDFLEVAFHTILCMRSVYPYDVFARRKKYSHPCYQSRHPGLNEYIS  83

Query:  67 RILQRHLRLWVLRGSVHRVVL  87
           R+L   LR+ + + +V +V+L
Sbjct:  84 RVLAA-LRIEIEKSTVRKVIL 103



ref|XP_537499.1| PREDICTED: similar to mitotic checkpoint component Mad2 [Canis familiaris]
(94 aa)

Score: 47 bits (111), Expect: 0.000309878
Length: 36, Idn/Pos/Gap = 23/26/0 (63%/72%/0%)

Query: 122 ESVVMREIQAIIRQITASVTFLPLLDEPCSFDLLVY 157
           E    + IQ  IRQITA+VTFLPLL   CSFDLL+Y
Sbjct:  24 EEKSQKAIQDEIRQITATVTFLPLLKVSCSFDLLIY  59



gb|AAH92858.1| Unknown (protein for MGC:110299) [Danio rerio]
ref|NP_001017595.1| hypothetical protein LOC550258 [Danio rerio]
(211 aa)

Score: 45 bits (107), Expect: 0.00084339
Length: 189, Idn/Pos/Gap = 43/87/13 (22%/46%/6%)

Query:  18 DTVIEFLRCAIYSILYQRGIYPPEMFRRASKFGTSVLVAQEAQLDSYIERILQRHLRLWV  77
           D + EFL  AI+ ILY R IYP  +F++  K+   V ++   QL+ YI+  L   ++  +
Sbjct:  17 DILCEFLEVAIHLILYVRDIYPSGIFQKRQKYNVPVQMSCHPQLNQYIQDTLH-CVKPLI  75

Query:  78 LRGSVHRVVLAFAATADPGRILERWHFDLHMEQRATEDSSVPRDESVVMREIQAIIRQIT 137
            +    +VV+           +ER+ F++         S      S V + ++A+I +I+
Sbjct:  76 EKNEAEKVVVVIMNKEH--HPVERFVFEISQPPLLAISSETLL--SHVEQLLRAMILKIS 131

Query: 138 ASVTFLPLLDEPCSFDLLVYTDPALEADANE--------WEESDAKLITAPRCEQVKLRS 189
                L      C+F +LV+T  A   +  +        W  +D + +     + + L++
Sbjct: 132 VCDAVLDSNPPGCTFTVLVHTREAATRNMEKVQVIKDFPWIVADEQEVHMEEAKLIPLKT 191

Query: 190 FTTNVHRVE 198
            T+++ +++
Sbjct: 192 MTSDILKMQ 200



emb|CAG01745.1| unnamed protein product [Tetraodon nigroviridis]
(432 aa)

Score: 45 bits (106), Expect: 0.00136836
Length: 141, Idn/Pos/Gap = 38/68/5 (26%/48%/3%)

Query:  18 DTVIEFLRCAIYSILYQRGIYPPEMFRRASKFGTSVLVAQEAQLDSYIERILQRHLRLWV  77
           D + EFL  AI+ ILY R +YP  +F++  K+   V ++   +L+ YI+  L   ++  +
Sbjct:  17 DILCEFLEVAIHLILYVREVYPSGIFQKRKKYNVPVQMSCHPELNQYIQDTLH-CMKPLI  75

Query:  78 LRGSVHRVVLAFAATADPGRILERWHFDLHMEQRATEDSSVPRDESVVMREIQAIIRQIT 137
            +    +VV+         R +ER+ F++      +  S      S V + ++A I +I+
Sbjct:  76 EKNDAEKVVVVIMDKEH--RPVERFVFEISQPTLLSISSDTLL--SHVEQLLRAFILKIS 131

Query: 138 ASVTFLPLLDEPCSFDLLVYT 158
                L      CSF +LV+T
Sbjct: 132 VCDAVLNNNPPGCSFSVLVHT 152



gb|AAH84331.1| Mad2l2-A protein [Xenopus laevis]
emb|CAC86900.1| mitotic arrest defective protein 2B [Xenopus laevis]
(211 aa)

Score: 43 bits (101), Expect: 0.00478351
Length: 194, Idn/Pos/Gap = 44/87/23 (22%/44%/11%)

Query:  18 DTVIEFLRCAIYSILYQRGIYPPEMFRRASKFGTSVLVAQEAQLDSYIERILQRHLRLWV  77
           D + EFL  A++ ILY R +YP  +F++  K+   V ++   +L+ YI+  L   ++  +
Sbjct:  17 DILCEFLEVAVHLILYVREVYPTGIFQKRKKYNVPVQMSCHPELNRYIQDTLH-CVKPLI  75

Query:  78 LRGSVHRVVLAFAATADPGRILERWH-----FDLHMEQRATEDSSVPRDESVVMREIQAI 132
            +  V +VV+          IL++ H     F   + Q      S     S V + ++A 
Sbjct:  76 EKNDVEKVVVV---------ILDKEHHPVERFVFEIAQPPLLSISSDSLLSHVEQLLRAF 126

Query: 133 IRQITASVTFLPLLDEPCSFDLLVYTDPALEADANE--------WEESDAKLITAPRCEQ 184
           I +I+     L      C+F LLV+T  A   +  +        W  +D + +       
Sbjct: 127 ILKISVCDAVLDNNPPGCTFTLLVHTREAATRNMEKIQVIKDFPWILADEQDVHMQEPRL 186

Query: 185 VKLRSFTTNVHRVE 198
           + L++ T+++ +++
Sbjct: 187 IPLKTMTSDILKMQ 200



gb|AAF20267.1| MAD2-like protein [Homo sapiens]
(211 aa)

Score: 42 bits (99), Expect: 0.00815943
Length: 194, Idn/Pos/Gap = 44/87/23 (22%/44%/11%)

Query:  18 DTVIEFLRCAIYSILYQRGIYPPEMFRRASKFGTSVLVAQEAQLDSYIERILQRHLRLWV  77
           D + EFL  A++ ILY R +YP  +F++  K+   V ++   +L+ YI+  L   ++  +
Sbjct:  17 DVLCEFLEVAVHLILYVREVYPVGIFQKRKKYNVPVQMSCHPELNQYIQDTLH-CVKPLL  75

Query:  78 LRGSVHRVVLAFAATADPGRILERWH-----FDLHMEQRATEDSSVPRDESVVMREIQAI 132
            +  V +VV+          IL++ H     F   + Q      S     S V + ++A 
Sbjct:  76 EKNDVEKVVVV---------ILDKEHRPVDKFVFEITQPPLLSISSDSLLSHVEQLLRAF 126

Query: 133 IRQITASVTFLPLLDEPCSFDLLVYTDPALEADANE--------WEESDAKLITAPRCEQ 184
           I +I+     L      C+F +LV+T  A   +  +        W  +D + +       
Sbjct: 127 ILKISVCDAVLDHNPPGCTFTVLVHTREAATRNMEKIQVIKDFPWILADEQDVHMHDPRL 186

Query: 185 VKLRSFTTNVHRVE 198
           + L++ T+++ +V+
Sbjct: 187 IPLKTMTSDILKVQ 200



gb|EAL28694.1| GA15539-PA [Drosophila pseudoobscura]
(200 aa)

Score: 42 bits (99), Expect: 0.00865018
Length: 183, Idn/Pos/Gap = 41/88/9 (22%/48%/4%)

Query:  16 STDTVIEFLRCAIYSILYQRGIYPPEMFRRASKFGTSVLVAQEAQLDSYIERILQRHLRL  75
           + D  +E L   +  ILY RGIYP ++F++   + T + V+    L++Y+  +L+    L
Sbjct:   6 ADDIHLEALEVILNHILYVRGIYPAQIFKKRRIYNTPIFVSIYPPLNTYLAGVLRSAREL  65

Query:  76 WVLRGSVHRVVLAFAATADPGRILERWHFDLHMEQRATEDSSVPRDESVVM---REIQAI 132
              R      +L + +   P   +E +   L +EQ   E +  P  +  ++   ++++A 
Sbjct:  66 LCRRELKCFEILLYHSENTP---IESYM--LQIEQLEPEAARQPAQDPHLIEYEQQLRAA 120

Query: 133 IRQITASVTFLPLLDEPCSFDLLVY-TDPALEADANEWEESDAKLITAPRCEQVKLRSFT 191
           + +++  +  LP L   C F + ++ T  A    ++E +  +   + A   +Q++ RS T
Sbjct: 121 LYKLSERLKPLPRLPGNCQFKVHLHTTQTAFVEFSHEAQYQEFPWLQAETPQQMEARSGT 180

Query: 192 TNV 194
            ++
Sbjct: 181 VSL 183



ref|XP_514391.1| PREDICTED: similar to Mitotic spindle assembly checkpoint protein MAD2B (MAD2-like 2) (hREV7) [Pan troglodytes]
(276 aa)

Score: 42 bits (98), Expect: 0.00924729
Length: 144, Idn/Pos/Gap = 38/70/5 (26%/48%/3%)

Query:  18 DTVIEFLRCAIYSILYQRGIYPPEMFRRASKFGTSVLVAQEAQLDSYIERILQRHLRLWV  77
           D + EFL  A++ ILY R +YP  +F++  K+   V ++   +L+ YI+  L   ++  +
Sbjct:  82 DVLCEFLEVAVHLILYVREVYPVGIFQKRKKYNVPVQMSCHPELNQYIQDTLH-CVKPLL 140

Query:  78 LRGSVHRVVLAFAATADPGRILERWHFDLHMEQRATEDSSVPRDESVVMREIQAIIRQIT 137
            +  V +VV+         R +E++ F++   Q      S     S V + ++A I +I+
Sbjct: 141 EKNDVEKVVVVILDKEH--RPVEKFVFEI--TQPPLLSISSDSLLSHVEQLLRAFILKIS 196

Query: 138 ASVTFLPLLDEPCSFDLLVYTDPA 161
                L      C+F +LV+T  A
Sbjct: 197 VCDAVLDHNPPGCTFTVLVHTREA 220